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Search of human proteins with 222136585
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222136585 timeless homolog [Homo sapiens]
(1208 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222136585 timeless homolog [Homo sapiens] 2386 0.0
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 44 0.001
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 43 0.002
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 42 0.004
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 42 0.004
gi|221219020 NYD-SP11 protein [Homo sapiens] 42 0.005
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 42 0.005
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 42 0.005
gi|118421089 chromodomain helicase DNA binding protein 2 isoform... 41 0.006
gi|110611184 chromodomain helicase DNA binding protein 2 isoform... 41 0.006
gi|17975763 myelin transcription factor 1 [Homo sapiens] 40 0.010
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 40 0.013
gi|55741661 hypothetical protein LOC57653 [Homo sapiens] 40 0.018
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 40 0.018
gi|112807226 hypothetical protein LOC91748 [Homo sapiens] 40 0.018
gi|44890062 hypothetical protein LOC91748 [Homo sapiens] 40 0.018
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 39 0.023
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 39 0.023
gi|4504063 golgin 97 [Homo sapiens] 39 0.023
gi|28274705 family with sequence similarity 9, member A [Homo sa... 39 0.030
gi|19913406 DNA topoisomerase II, alpha isozyme [Homo sapiens] 39 0.039
gi|16262452 cingulin [Homo sapiens] 39 0.039
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 38 0.051
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 38 0.051
gi|20336305 B-cell CLL/lymphoma 11A isoform 1 [Homo sapiens] 38 0.051
gi|20336307 B-cell CLL/lymphoma 11A isoform 2 [Homo sapiens] 38 0.051
gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sap... 38 0.051
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 38 0.051
gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo sa... 38 0.051
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi... 38 0.067
>gi|222136585 timeless homolog [Homo sapiens]
Length = 1208
Score = 2386 bits (6184), Expect = 0.0
Identities = 1208/1208 (100%), Positives = 1208/1208 (100%)
Query: 1 MDLHMMNCELLATCSALGYLEGDTYHKEPDCLESVKDLIRYLRHEDETRDVRQQLGAAQI 60
MDLHMMNCELLATCSALGYLEGDTYHKEPDCLESVKDLIRYLRHEDETRDVRQQLGAAQI
Sbjct: 1 MDLHMMNCELLATCSALGYLEGDTYHKEPDCLESVKDLIRYLRHEDETRDVRQQLGAAQI 60
Query: 61 LQSDLLPILTQHHQDKPLFDAVIRLMVNLTQPALLCFGNLPKEPSFRHHFLQVLTYLQAY 120
LQSDLLPILTQHHQDKPLFDAVIRLMVNLTQPALLCFGNLPKEPSFRHHFLQVLTYLQAY
Sbjct: 61 LQSDLLPILTQHHQDKPLFDAVIRLMVNLTQPALLCFGNLPKEPSFRHHFLQVLTYLQAY 120
Query: 121 KEAFASEKAFGVLSETLYELLQLGWEERQEEDNLLIERILLLVRNILHVPADLDQEKKID 180
KEAFASEKAFGVLSETLYELLQLGWEERQEEDNLLIERILLLVRNILHVPADLDQEKKID
Sbjct: 121 KEAFASEKAFGVLSETLYELLQLGWEERQEEDNLLIERILLLVRNILHVPADLDQEKKID 180
Query: 181 DDASAHDQLLWAIHLSGLDDLLLFLASSSAEEQWSLHVLEIVSLMFRDQNPEQLAGVGQG 240
DDASAHDQLLWAIHLSGLDDLLLFLASSSAEEQWSLHVLEIVSLMFRDQNPEQLAGVGQG
Sbjct: 181 DDASAHDQLLWAIHLSGLDDLLLFLASSSAEEQWSLHVLEIVSLMFRDQNPEQLAGVGQG 240
Query: 241 RLAQERSADFAELEVLRQREMAEKKTRALQRGNRHSRFGGSYIVQGLKSIGERDLIFHKG 300
RLAQERSADFAELEVLRQREMAEKKTRALQRGNRHSRFGGSYIVQGLKSIGERDLIFHKG
Sbjct: 241 RLAQERSADFAELEVLRQREMAEKKTRALQRGNRHSRFGGSYIVQGLKSIGERDLIFHKG 300
Query: 301 LHNLRNYSSDLGKQPKKVPKRRQAARELSIQRRSALNVRLFLRDFCSEFLENCYNRLMGS 360
LHNLRNYSSDLGKQPKKVPKRRQAARELSIQRRSALNVRLFLRDFCSEFLENCYNRLMGS
Sbjct: 301 LHNLRNYSSDLGKQPKKVPKRRQAARELSIQRRSALNVRLFLRDFCSEFLENCYNRLMGS 360
Query: 361 VKDHLLREKAQQHDETYYMWALAFFMAFNRAASFRPGLVSETLSVRTFHFIEQNLTNYYE 420
VKDHLLREKAQQHDETYYMWALAFFMAFNRAASFRPGLVSETLSVRTFHFIEQNLTNYYE
Sbjct: 361 VKDHLLREKAQQHDETYYMWALAFFMAFNRAASFRPGLVSETLSVRTFHFIEQNLTNYYE 420
Query: 421 MMLTDRKEAASWARRMHLALKAYQELLATVNEMDISPDEAVRESSRIIKNNIFYVMEYRE 480
MMLTDRKEAASWARRMHLALKAYQELLATVNEMDISPDEAVRESSRIIKNNIFYVMEYRE
Sbjct: 421 MMLTDRKEAASWARRMHLALKAYQELLATVNEMDISPDEAVRESSRIIKNNIFYVMEYRE 480
Query: 481 LFLALFRKFDERCQPRSFLRDLVETTHLFLKMLERFCRSRGNLVVQNKQKKRRKKKKKVL 540
LFLALFRKFDERCQPRSFLRDLVETTHLFLKMLERFCRSRGNLVVQNKQKKRRKKKKKVL
Sbjct: 481 LFLALFRKFDERCQPRSFLRDLVETTHLFLKMLERFCRSRGNLVVQNKQKKRRKKKKKVL 540
Query: 541 DQAIVSGNVPSSPEEVEAVWPALAEQLQCCAQNSELSMDSVVPFDAASEVPVEEQRAEAM 600
DQAIVSGNVPSSPEEVEAVWPALAEQLQCCAQNSELSMDSVVPFDAASEVPVEEQRAEAM
Sbjct: 541 DQAIVSGNVPSSPEEVEAVWPALAEQLQCCAQNSELSMDSVVPFDAASEVPVEEQRAEAM 600
Query: 601 VRIQDCLLAGQAPQALTLLRSAREVWPEGDVFGSQDISPEEEIQLLKQILSAPLPRQQGP 660
VRIQDCLLAGQAPQALTLLRSAREVWPEGDVFGSQDISPEEEIQLLKQILSAPLPRQQGP
Sbjct: 601 VRIQDCLLAGQAPQALTLLRSAREVWPEGDVFGSQDISPEEEIQLLKQILSAPLPRQQGP 660
Query: 661 EERGAEEEEEEEEEEEEELQVVQVSEKEFNFLDYLKRFACSTVVRAYVLLLRSYQQNSAH 720
EERGAEEEEEEEEEEEEELQVVQVSEKEFNFLDYLKRFACSTVVRAYVLLLRSYQQNSAH
Sbjct: 661 EERGAEEEEEEEEEEEEELQVVQVSEKEFNFLDYLKRFACSTVVRAYVLLLRSYQQNSAH 720
Query: 721 TNHCIVKMLHRLAHDLKMEALLFQLSVFCLFNRLLSDPAAGAYKELVTFAKYILGKFFAL 780
TNHCIVKMLHRLAHDLKMEALLFQLSVFCLFNRLLSDPAAGAYKELVTFAKYILGKFFAL
Sbjct: 721 TNHCIVKMLHRLAHDLKMEALLFQLSVFCLFNRLLSDPAAGAYKELVTFAKYILGKFFAL 780
Query: 781 AAVNQKAFVELLFWKNTAVVREMTEGYGSLDDRSSSRRAPTWSPEEEAHLRELYLANKDV 840
AAVNQKAFVELLFWKNTAVVREMTEGYGSLDDRSSSRRAPTWSPEEEAHLRELYLANKDV
Sbjct: 781 AAVNQKAFVELLFWKNTAVVREMTEGYGSLDDRSSSRRAPTWSPEEEAHLRELYLANKDV 840
Query: 841 EGQDVVEAILAHLNTVPRTRKQIIHHLVQMGLADSVKDFQRKGTHIVLWTGDQELELQRL 900
EGQDVVEAILAHLNTVPRTRKQIIHHLVQMGLADSVKDFQRKGTHIVLWTGDQELELQRL
Sbjct: 841 EGQDVVEAILAHLNTVPRTRKQIIHHLVQMGLADSVKDFQRKGTHIVLWTGDQELELQRL 900
Query: 901 FEEFRDSDDVLGHIMKNITAKRSRARIVDKLLALGLVAERRELYKKRQKKLASSILPNGA 960
FEEFRDSDDVLGHIMKNITAKRSRARIVDKLLALGLVAERRELYKKRQKKLASSILPNGA
Sbjct: 901 FEEFRDSDDVLGHIMKNITAKRSRARIVDKLLALGLVAERRELYKKRQKKLASSILPNGA 960
Query: 961 ESLKDFCQEDLEEEENLPEEDSEEEEEGGSEAEQVQGSLVLSNENLGQSLHQEGFSIPLL 1020
ESLKDFCQEDLEEEENLPEEDSEEEEEGGSEAEQVQGSLVLSNENLGQSLHQEGFSIPLL
Sbjct: 961 ESLKDFCQEDLEEEENLPEEDSEEEEEGGSEAEQVQGSLVLSNENLGQSLHQEGFSIPLL 1020
Query: 1021 WLQNCLIRAADDREEDGCSQAVPLVPLTEENEEAMENEQFQQLLRKLGVRPPASGQETFW 1080
WLQNCLIRAADDREEDGCSQAVPLVPLTEENEEAMENEQFQQLLRKLGVRPPASGQETFW
Sbjct: 1021 WLQNCLIRAADDREEDGCSQAVPLVPLTEENEEAMENEQFQQLLRKLGVRPPASGQETFW 1080
Query: 1081 RIPAKLSPTQLRRAAASLSQPEEEQKLQPELQPKVPGEQGSDEEHCKEHRAQALRALLLA 1140
RIPAKLSPTQLRRAAASLSQPEEEQKLQPELQPKVPGEQGSDEEHCKEHRAQALRALLLA
Sbjct: 1081 RIPAKLSPTQLRRAAASLSQPEEEQKLQPELQPKVPGEQGSDEEHCKEHRAQALRALLLA 1140
Query: 1141 HKKKAGLASPEEEDAVGKEPLKAAPKKRQLLDSDEEQEEDEGRNRAPELGAPGIQKKKRY 1200
HKKKAGLASPEEEDAVGKEPLKAAPKKRQLLDSDEEQEEDEGRNRAPELGAPGIQKKKRY
Sbjct: 1141 HKKKAGLASPEEEDAVGKEPLKAAPKKRQLLDSDEEQEEDEGRNRAPELGAPGIQKKKRY 1200
Query: 1201 QIEDDEDD 1208
QIEDDEDD
Sbjct: 1201 QIEDDEDD 1208
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 43.5 bits (101), Expect = 0.001
Identities = 66/249 (26%), Positives = 98/249 (39%), Gaps = 26/249 (10%)
Query: 914 IMKNITAKRSRARIVDKLLALGLVAERRELYKKR-QKKLASSILPNGAE---SLKDFCQE 969
++ ++ AK S+A KL GL A R K +K +L AE S D +E
Sbjct: 1760 LLCSMVAKNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPFCLLLREAEARSSFSDSSEE 1819
Query: 970 DLEEEENLPEEDSEEEEEGGSEAEQVQGSLVLSNENLGQSLHQEGFSIPLLWLQNCLIRA 1029
+++E+ EED EEE E EA L L L + G + + A
Sbjct: 1820 SFDQDESSEEEDEEEELEEEDEASGGGYRLGARERALSPGLEESGLGLLARF-------A 1872
Query: 1030 ADDREEDGCSQAVPLVPLTEENEEAMENEQFQQLLRKLGVRPPASGQETFWRIPAKLSPT 1089
A ++ +V L E ++A + E+ Q L LG + E+ ++ K SP
Sbjct: 1873 ASALPSPTVGPSLSVVQL-EAKQKARKKEERQSL---LGTEFEYTDSESEVKV-RKRSPA 1927
Query: 1090 QLRRAAASLSQPEEEQKLQPELQPKVPGEQGSD---EEHCKEHRAQALRALLLAHKKKAG 1146
L R L +P P L PG +G D + K + +A L K+ G
Sbjct: 1928 GLLRPKKGLGEP------GPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPG 1981
Query: 1147 L-ASPEEED 1154
A PE D
Sbjct: 1982 FEAGPEASD 1990
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 42.7 bits (99), Expect = 0.002
Identities = 59/225 (26%), Positives = 87/225 (38%), Gaps = 44/225 (19%)
Query: 968 QEDLEEEENLPEEDSEEEEEGGSEAEQVQGSLVLSNENLGQSLHQEGFSIPLLWLQNCLI 1027
+E+ EEEE EE+ EEEEE E E+ E + +E F
Sbjct: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEF------------ 935
Query: 1028 RAADDREEDGCSQAVPLVPLTEENEEAMENEQFQQLLRKLGVRPPASGQETFWRIPAKLS 1087
EE+G + EE EE E E+ + + L E P L
Sbjct: 936 -----EEEEGELE-------EEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLP 983
Query: 1088 PTQLRRAAASLSQPEEEQKLQPELQPKVPGEQGSDEEHCKEHRAQALRALLLAHKKKAGL 1147
P +L PE K+QPE +P+ PG EE E A A LA + L
Sbjct: 984 P--------ALPPPESPPKVQPEPEPE-PGLLLEVEEPGTEEERGADTAPTLAPE---AL 1031
Query: 1148 ASPEEEDAVGKEPLKAAPKKRQLLDSDE-------EQEEDEGRNR 1185
S E + G+ P A P ++L++ + E+E ++G ++
Sbjct: 1032 PSQGEVEREGESP-AAGPPPQELVEEEPSAPPTLLEEETEDGSDK 1075
Score = 38.5 bits (88), Expect = 0.039
Identities = 22/63 (34%), Positives = 35/63 (55%), Gaps = 4/63 (6%)
Query: 627 PEGDVFGSQDISPEEEIQLLKQILSAPLPRQQGPEERGAEEEEEEEEEEEEELQVVQVSE 686
PEG G + EE++ +++ ++ EE EEEEEEEEEEEE+ + + E
Sbjct: 862 PEGTPGGGGPPALEEDLT----VININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDE 917
Query: 687 KEF 689
+E+
Sbjct: 918 EEY 920
Score = 37.0 bits (84), Expect = 0.11
Identities = 17/29 (58%), Positives = 22/29 (75%)
Query: 661 EERGAEEEEEEEEEEEEELQVVQVSEKEF 689
EE G EEEEEEE+EEEE ++ +V + EF
Sbjct: 937 EEEGELEEEEEEEDEEEEEELEEVEDLEF 965
Score = 32.0 bits (71), Expect = 3.7
Identities = 16/36 (44%), Positives = 23/36 (63%)
Query: 961 ESLKDFCQEDLEEEENLPEEDSEEEEEGGSEAEQVQ 996
E ++F +E EEE L EE+ EE+EE E E+V+
Sbjct: 926 EEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVE 961
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo
sapiens]
Length = 916
Score = 42.0 bits (97), Expect = 0.004
Identities = 59/264 (22%), Positives = 107/264 (40%), Gaps = 35/264 (13%)
Query: 945 KKRQKKLASSILPNGAESLKDFCQEDLEEEENLPEEDSEE----------------EEEG 988
K ++ ++I A S+K+ +E EE+E PE + EE EEEG
Sbjct: 466 KSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEG 525
Query: 989 GSEAEQVQGSLVLSNENLGQSLHQEGFSIPLLWLQNCLIRAADDREEDGCSQAVPLVPLT 1048
E E+ Q +E +EG S + + +E+G ++A
Sbjct: 526 EKEEEEGQEEEEEEDEGAKSDQAEEGGS-----EKEGSSEKEEGEQEEGETEAEAEGEEA 580
Query: 1049 EENEEAMENEQFQQLLRKLGVRPPASGQE-TFWRIPAKLSPTQLRRAAASLSQPEEEQKL 1107
E EE E+ +++ K + A ++ + P SP + + + P EE+
Sbjct: 581 EAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGK 640
Query: 1108 QPELQPKVPGEQGSDEEHCKEHRAQALRALLLAHKKKAGLASPEEEDA---VGKEPLKAA 1164
P PK P E+ + ++ ++ + K SP EE A V K P++ A
Sbjct: 641 SP--VPKSPVEE--------KGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEA 690
Query: 1165 PKKRQLLDSDEEQEEDEGRNRAPE 1188
K ++ ++++EE++ AP+
Sbjct: 691 KSKAEVGKGEQKEEEEKEVKEAPK 714
Score = 37.0 bits (84), Expect = 0.11
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 7/90 (7%)
Query: 589 EVPVEEQRAEAMVRIQDCLLAGQAPQALTLLRSAREVWPEGDVFGSQDISPEEEIQLLKQ 648
E VE++++E +++ L A A+++ +E E + + + EEE+ K
Sbjct: 459 ETKVEDEKSE----MEEALTAITEELAVSMKEEKKEAAEEKE---EEPEAEEEEVAAKKS 511
Query: 649 ILSAPLPRQQGPEERGAEEEEEEEEEEEEE 678
+ A P + E EEE +EEEEEE+E
Sbjct: 512 PVKATAPEVKEEEGEKEEEEGQEEEEEEDE 541
Score = 31.2 bits (69), Expect = 6.2
Identities = 35/155 (22%), Positives = 61/155 (39%), Gaps = 20/155 (12%)
Query: 534 KKKKKVLDQAIVSGNVPSSPEEVEAVWPALAEQLQCCAQNSELSMDSVVPFDAASEVPVE 593
K + K +++ I V E+E A+ E+L + + A+E E
Sbjct: 447 KVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKE---------AAEEKEE 497
Query: 594 EQRAEAMVRIQDCLLAGQAPQALTLLRSAREVWPEGDVFGSQDISPEEEIQLLKQILSAP 653
E AE ++ + A ++P T E + + G ++ E+E Q
Sbjct: 498 EPEAE-----EEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQA---- 548
Query: 654 LPRQQGPEERGAEEEEEEEEEEEEELQVVQVSEKE 688
+ G E+ G+ E+EE E+EE E + E E
Sbjct: 549 --EEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAE 581
Score = 30.8 bits (68), Expect = 8.1
Identities = 33/117 (28%), Positives = 53/117 (45%), Gaps = 18/117 (15%)
Query: 1103 EEQKLQPELQPKVPGEQGSDEE---HCKEHRAQALRALLLAHKKKAGLASPEEEDAVGKE 1159
EE K++ E EE KE + +A A +K+ + EEE A K
Sbjct: 458 EETKVEDEKSEMEEALTAITEELAVSMKEEKKEA------AEEKEEEPEAEEEEVAAKKS 511
Query: 1160 PLKA-AP-------KKRQLLDSDEEQEEDEGRNRAPELGAPGIQKKKRYQIEDDEDD 1208
P+KA AP +K + +EE+EEDEG ++ + G +K+ + E+ E +
Sbjct: 512 PVKATAPEVKEEEGEKEEEEGQEEEEEEDEGA-KSDQAEEGGSEKEGSSEKEEGEQE 567
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo
sapiens]
Length = 540
Score = 42.0 bits (97), Expect = 0.004
Identities = 59/264 (22%), Positives = 107/264 (40%), Gaps = 35/264 (13%)
Query: 945 KKRQKKLASSILPNGAESLKDFCQEDLEEEENLPEEDSEE----------------EEEG 988
K ++ ++I A S+K+ +E EE+E PE + EE EEEG
Sbjct: 90 KSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEG 149
Query: 989 GSEAEQVQGSLVLSNENLGQSLHQEGFSIPLLWLQNCLIRAADDREEDGCSQAVPLVPLT 1048
E E+ Q +E +EG S + + +E+G ++A
Sbjct: 150 EKEEEEGQEEEEEEDEGAKSDQAEEGGS-----EKEGSSEKEEGEQEEGETEAEAEGEEA 204
Query: 1049 EENEEAMENEQFQQLLRKLGVRPPASGQE-TFWRIPAKLSPTQLRRAAASLSQPEEEQKL 1107
E EE E+ +++ K + A ++ + P SP + + + P EE+
Sbjct: 205 EAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGK 264
Query: 1108 QPELQPKVPGEQGSDEEHCKEHRAQALRALLLAHKKKAGLASPEEEDA---VGKEPLKAA 1164
P PK P E+ + ++ ++ + K SP EE A V K P++ A
Sbjct: 265 SP--VPKSPVEE--------KGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEA 314
Query: 1165 PKKRQLLDSDEEQEEDEGRNRAPE 1188
K ++ ++++EE++ AP+
Sbjct: 315 KSKAEVGKGEQKEEEEKEVKEAPK 338
Score = 37.0 bits (84), Expect = 0.11
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 7/90 (7%)
Query: 589 EVPVEEQRAEAMVRIQDCLLAGQAPQALTLLRSAREVWPEGDVFGSQDISPEEEIQLLKQ 648
E VE++++E +++ L A A+++ +E E + + + EEE+ K
Sbjct: 83 ETKVEDEKSE----MEEALTAITEELAVSMKEEKKEAAEEKE---EEPEAEEEEVAAKKS 135
Query: 649 ILSAPLPRQQGPEERGAEEEEEEEEEEEEE 678
+ A P + E EEE +EEEEEE+E
Sbjct: 136 PVKATAPEVKEEEGEKEEEEGQEEEEEEDE 165
Score = 31.2 bits (69), Expect = 6.2
Identities = 35/155 (22%), Positives = 61/155 (39%), Gaps = 20/155 (12%)
Query: 534 KKKKKVLDQAIVSGNVPSSPEEVEAVWPALAEQLQCCAQNSELSMDSVVPFDAASEVPVE 593
K + K +++ I V E+E A+ E+L + + A+E E
Sbjct: 71 KVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKE---------AAEEKEE 121
Query: 594 EQRAEAMVRIQDCLLAGQAPQALTLLRSAREVWPEGDVFGSQDISPEEEIQLLKQILSAP 653
E AE ++ + A ++P T E + + G ++ E+E Q
Sbjct: 122 EPEAE-----EEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQA---- 172
Query: 654 LPRQQGPEERGAEEEEEEEEEEEEELQVVQVSEKE 688
+ G E+ G+ E+EE E+EE E + E E
Sbjct: 173 --EEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAE 205
Score = 30.8 bits (68), Expect = 8.1
Identities = 33/117 (28%), Positives = 53/117 (45%), Gaps = 18/117 (15%)
Query: 1103 EEQKLQPELQPKVPGEQGSDEE---HCKEHRAQALRALLLAHKKKAGLASPEEEDAVGKE 1159
EE K++ E EE KE + +A A +K+ + EEE A K
Sbjct: 82 EETKVEDEKSEMEEALTAITEELAVSMKEEKKEA------AEEKEEEPEAEEEEVAAKKS 135
Query: 1160 PLKA-AP-------KKRQLLDSDEEQEEDEGRNRAPELGAPGIQKKKRYQIEDDEDD 1208
P+KA AP +K + +EE+EEDEG ++ + G +K+ + E+ E +
Sbjct: 136 PVKATAPEVKEEEGEKEEEEGQEEEEEEDEGA-KSDQAEEGGSEKEGSSEKEEGEQE 191
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 41.6 bits (96), Expect = 0.005
Identities = 66/282 (23%), Positives = 118/282 (41%), Gaps = 68/282 (24%)
Query: 938 AERRELYKKRQKKLASSI--LPNGAESLKDFCQEDLEEEENLPEEDSE----EEEEGGSE 991
+E+R K +KKLA L N + + ++ EEE L + SE +EEEGG E
Sbjct: 2126 SEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIE 2185
Query: 992 AEQVQGSLVLSNENLGQSLHQEGFSIPLL---WLQNCLIRAADDREEDGCSQAVPLVPLT 1048
E+V IP L W + + D +E SQ +
Sbjct: 2186 EEEV---------------------IPFLKRRWRKRKEAKRGDKPKEKFSSQ------VD 2218
Query: 1049 EENEEAMENEQFQQLLRKLGVRPPASGQETFWRIPAKLSPTQLRRAAASLSQPEEEQKLQ 1108
E E +E+ + LL +L + S +E R + R + + EEE+K +
Sbjct: 2219 EVESEEHFSEEMESLLDELEKQESLSSEEEEER------EEEEEREEEEVREEEEERKEE 2272
Query: 1109 PELQPK-VPGEQGSDEEHCKEHRAQALRALLLAHKKKAGLASPEEEDAVGKEPLKAAPKK 1167
E + K V E+ ++ KE + + ++ ++K + S EE +++
Sbjct: 2273 EEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESL----------- 2321
Query: 1168 RQLLDSDEEQEE-----DEGRNRAPELGAPGIQKKKRYQIED 1204
SDEE+EE +E +R E+ ++K+K++++++
Sbjct: 2322 -----SDEEEEEESCSLEEEVDREKEI----LKKEKQFKLQE 2354
Score = 37.4 bits (85), Expect = 0.087
Identities = 24/94 (25%), Positives = 49/94 (52%), Gaps = 3/94 (3%)
Query: 1112 QPKVPGEQGSDEEHCKEHRAQALRALLLAHKKKAGLASPEEEDAVGKEPLKAAPKKRQLL 1171
+PK DE +EH ++ + +LL +K+ L+S EEE+ +E + ++
Sbjct: 2208 KPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEE---REEEEEREEEEVRE 2264
Query: 1172 DSDEEQEEDEGRNRAPELGAPGIQKKKRYQIEDD 1205
+ +E +EE+EG + E +KKK+ + +++
Sbjct: 2265 EEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEE 2298
Score = 34.3 bits (77), Expect = 0.74
Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 632 FGSQ--DISPEEEIQLLKQILSAPLPRQQGPEERGAEEEEEEEEEEEEELQVVQVSEKE 688
F SQ ++ EE + L L +Q+ EE EEEEE EEEE++ + KE
Sbjct: 2213 FSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKE 2271
Score = 32.0 bits (71), Expect = 3.7
Identities = 19/50 (38%), Positives = 30/50 (60%), Gaps = 2/50 (4%)
Query: 641 EEIQLLKQILSAPLPRQQGPEERGAEE--EEEEEEEEEEELQVVQVSEKE 688
+E++ + + S ++ EER EE EEEEE +EEEE + QV ++E
Sbjct: 2235 DELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEE 2284
Score = 31.2 bits (69), Expect = 6.2
Identities = 21/59 (35%), Positives = 28/59 (47%)
Query: 630 DVFGSQDISPEEEIQLLKQILSAPLPRQQGPEERGAEEEEEEEEEEEEELQVVQVSEKE 688
D S++ EE LL ++ + EER EEE EEEE EEE + + E E
Sbjct: 2218 DEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGE 2276
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens]
Length = 436
Score = 41.6 bits (96), Expect = 0.005
Identities = 44/240 (18%), Positives = 98/240 (40%), Gaps = 17/240 (7%)
Query: 972 EEEENLPEEDS---EEEEEGGSEAEQVQGSLVLSNENLGQSLHQEGFSIPLLWLQNCLIR 1028
E+E + E++ E+EE+ G + EQ+Q E +G+ Q + Q ++
Sbjct: 189 EQEGQMGEQEGQMGEQEEQMGEQEEQMQKQ----EEQMGEQEEQMRKQEEQMGEQEEQVQ 244
Query: 1029 AADDREEDGCSQAVPLVPLTEENEEAMENEQFQQLLRKLGVRPPASGQETFWRIPAKLSP 1088
+++ + Q E EE M ++ Q L +K ++T
Sbjct: 245 KQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQK---------EQTEQEEQTGEQE 295
Query: 1089 TQLRRAAASLSQPEEEQKLQPELQPKVPGEQGSDEEHCKEHRAQALRALLLAHKKKAGLA 1148
Q+R + + EE+ + Q E + + G EE E + Q K++ +
Sbjct: 296 EQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMG 355
Query: 1149 SPEEEDAVGKEPLKAAPKKRQLLDSDEEQEEDEGRNRAPELGAPGIQK-KKRYQIEDDED 1207
EE+ +E ++ ++ + + ++E++ R + ++G Q +++ Q+ + E+
Sbjct: 356 EQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEE 415
Score = 33.9 bits (76), Expect = 0.96
Identities = 43/226 (19%), Positives = 87/226 (38%), Gaps = 23/226 (10%)
Query: 972 EEEENLPEEDSE---EEEEGGSEAEQVQGSLVLSNENLGQSLHQEGFSIPLLWLQNCLIR 1028
++EE + E++ + +EE+ G + EQVQ + Q QE
Sbjct: 217 KQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQE--------------E 262
Query: 1029 AADDREEDGCSQAVPLVPLTEENE-EAMENEQFQQLLRKLGVRPPASGQETFWRIPAKLS 1087
++EE Q ++ E+ E E EQ +Q+ + Q +
Sbjct: 263 QMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQ 322
Query: 1088 PTQLRRAAASLSQPEEEQKLQPELQPKVPGEQGSDEEHCKEHRAQALRALLLAHKKKAGL 1147
Q+ + + + +E+ Q E K + G EE ++ Q + K++ +
Sbjct: 323 EEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQM 382
Query: 1148 ASPEE-----EDAVGKEPLKAAPKKRQLLDSDEEQEEDEGRNRAPE 1188
EE E+ +G++ + +K Q+ + +E+ E + + R E
Sbjct: 383 RKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQE 428
Score = 33.5 bits (75), Expect = 1.3
Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 2/51 (3%)
Query: 640 EEEIQLLKQILSAPLPRQQGPEERGAEEEEEEEEEEEEEL--QVVQVSEKE 688
E+E Q+LKQ Q G +E E+EE+ E+EE++ Q Q+ E+E
Sbjct: 273 EQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQE 323
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 41.6 bits (96), Expect = 0.005
Identities = 58/321 (18%), Positives = 129/321 (40%), Gaps = 41/321 (12%)
Query: 893 QELELQRLFEEFRDSDDVLGHIMKNITAKRSRARIVDKLLALGLVAERRE---LYKKRQK 949
QE ++Q E+ ++ ++ + + I + + R ++++ RR+ +++K +K
Sbjct: 366 QEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 425
Query: 950 -KLASSILPNGAESLKDFCQEDLEEEENLPEEDSEEEEEGGSEAEQVQGSLVLSNENLGQ 1008
+ ++ E +++ ++ E+E+ +E+ +EEE E E+ Q
Sbjct: 426 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ------------ 473
Query: 1009 SLHQEGFSIPLLWLQNCLIRAADDREEDGCSQAVPLVPLTEENEEAMENEQFQQLLRKLG 1068
QE +W Q IR +++ + E+ E+ E+ K+
Sbjct: 474 --EQEA----KMWRQEEKIREQEEK-------------IREQEEKMWRQEEKIHEQEKIR 514
Query: 1069 VRPPASGQETFWRIPAKL-SPTQLRRAAASLSQPEEEQKLQPELQPKVPGEQGSDEEHCK 1127
QE WR K+ ++ R + + EE+ + Q E + + EE +
Sbjct: 515 EEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIR 574
Query: 1128 EHRAQALRALLLAHKKKAGLASPEE-----EDAVGKEPLKAAPKKRQLLDSDEEQEEDEG 1182
E + R +++ + EE E+ ++ K ++ ++ + +E+ +E E
Sbjct: 575 EQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 634
Query: 1183 RNRAPELGAPGIQKKKRYQIE 1203
+ R E +KK R Q E
Sbjct: 635 KMRRQEEKIREQEKKIREQEE 655
>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
[Homo sapiens]
Length = 1828
Score = 41.2 bits (95), Expect = 0.006
Identities = 59/253 (23%), Positives = 95/253 (37%), Gaps = 30/253 (11%)
Query: 968 QEDLEEEENLPEEDSEEEEEG---GSEAEQVQGSLVLSNENLGQSLHQEGFSIPLLWLQN 1024
+ED N + EE G GS++E QGS S + E
Sbjct: 10 EEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSE-------- 61
Query: 1025 CLIRAADDREEDGCSQAVPLVPLTEENEEAMENEQFQQLLRKLGVRPPASGQETFWRIPA 1084
++ E S++ P++P +E + A + E+ + + P G R
Sbjct: 62 ---SQSESESESAGSKSQPVLPEAKE-KPASKKERIADVKKMWEEYPDVYGVRRSNRSRQ 117
Query: 1085 KLSPTQLRRAAASLSQ---PEEEQKLQPELQPKVPGEQGSDEEHCKEHRAQALRALLLAH 1141
+ S ++ A+S S+ P+ + Q + Q K E DE+ Q A
Sbjct: 118 EPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQE------QGTSAESEPE 171
Query: 1142 KKKAGLASPEEEDAVGKEPLKAAPK----KRQLLDS-DEEQEEDEG-RNRAPELGAPGIQ 1195
+KK P V K +K PK KR+ DS DE+ ++DE + + A +
Sbjct: 172 QKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVS 231
Query: 1196 KKKRYQIEDDEDD 1208
K+ E D DD
Sbjct: 232 YKEDDDFETDSDD 244
>gi|110611184 chromodomain helicase DNA binding protein 2 isoform 2
[Homo sapiens]
Length = 501
Score = 41.2 bits (95), Expect = 0.006
Identities = 59/253 (23%), Positives = 95/253 (37%), Gaps = 30/253 (11%)
Query: 968 QEDLEEEENLPEEDSEEEEEG---GSEAEQVQGSLVLSNENLGQSLHQEGFSIPLLWLQN 1024
+ED N + EE G GS++E QGS S + E
Sbjct: 10 EEDSSLHSNASSHSASEEASGSDSGSQSESEQGSDPGSGHGSESNSSSESSE-------- 61
Query: 1025 CLIRAADDREEDGCSQAVPLVPLTEENEEAMENEQFQQLLRKLGVRPPASGQETFWRIPA 1084
++ E S++ P++P +E + A + E+ + + P G R
Sbjct: 62 ---SQSESESESAGSKSQPVLPEAKE-KPASKKERIADVKKMWEEYPDVYGVRRSNRSRQ 117
Query: 1085 KLSPTQLRRAAASLSQ---PEEEQKLQPELQPKVPGEQGSDEEHCKEHRAQALRALLLAH 1141
+ S ++ A+S S+ P+ + Q + Q K E DE+ Q A
Sbjct: 118 EPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQE------QGTSAESEPE 171
Query: 1142 KKKAGLASPEEEDAVGKEPLKAAPK----KRQLLDS-DEEQEEDEG-RNRAPELGAPGIQ 1195
+KK P V K +K PK KR+ DS DE+ ++DE + + A +
Sbjct: 172 QKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVS 231
Query: 1196 KKKRYQIEDDEDD 1208
K+ E D DD
Sbjct: 232 YKEDDDFETDSDD 244
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 40.4 bits (93), Expect = 0.010
Identities = 26/62 (41%), Positives = 34/62 (54%), Gaps = 7/62 (11%)
Query: 634 SQDISPE-------EEIQLLKQILSAPLPRQQGPEERGAEEEEEEEEEEEEELQVVQVSE 686
SQD+ P+ EE K ILS ++ EE EEE+EEEEEEEEE + + E
Sbjct: 232 SQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEE 291
Query: 687 KE 688
+E
Sbjct: 292 EE 293
Score = 37.0 bits (84), Expect = 0.11
Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 6/97 (6%)
Query: 592 VEEQRAEAMVRIQDCLLAGQAPQALTLLRSAREVWPEGDVFGSQDISPEEEIQLLKQILS 651
++ + AE +V + PQ+L S +G + ++ EEE + ++
Sbjct: 216 IQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEE--- 272
Query: 652 APLPRQQGPEERGAEEEEEEEEEEEEELQVVQVSEKE 688
++ EE EEEEEEEEEEEEE + + E+E
Sbjct: 273 ---EDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306
Score = 32.3 bits (72), Expect = 2.8
Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 11/93 (11%)
Query: 968 QEDLEEEENLPEEDSEEEEEGGSEAEQVQGSLVLSNENLGQSLHQE-----GFSIPLLWL 1022
+E+ EEEE EE+ EEEEE E E+ V+ E+ + Q+ G P
Sbjct: 279 EEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKP 338
Query: 1023 QNCLI---RAADDREEDGCSQAVPLVPLTEENE 1052
+ +I R+ DD++ED S+ +T+E+E
Sbjct: 339 EYSVIVEVRSDDDKDEDTHSRK---STVTDESE 368
Score = 31.6 bits (70), Expect = 4.8
Identities = 15/27 (55%), Positives = 18/27 (66%)
Query: 968 QEDLEEEENLPEEDSEEEEEGGSEAEQ 994
+ED EEEE EE+ EEEEE E E+
Sbjct: 272 EEDEEEEEEEEEEEEEEEEEEEEEEEE 298
Score = 30.8 bits (68), Expect = 8.1
Identities = 27/104 (25%), Positives = 45/104 (43%), Gaps = 9/104 (8%)
Query: 581 VVPFDAASEVPVEEQRAEAMV--RIQDCLLAGQAPQALTLLRSAREVWPEGDVFGSQDIS 638
+ P DA V V +R++ + ++D + Q L + E + ++
Sbjct: 216 IQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDE 275
Query: 639 PEEEIQLLKQILSAPLPRQQGPEERGAEEEEEEEEEEEEELQVV 682
EEE + ++ ++ EE EEEEEEEEEEE V+
Sbjct: 276 EEEEEEEEEE-------EEEEEEEEEEEEEEEEEEEEEAAPDVI 312
Score = 30.8 bits (68), Expect = 8.1
Identities = 18/48 (37%), Positives = 27/48 (56%)
Query: 947 RQKKLASSILPNGAESLKDFCQEDLEEEENLPEEDSEEEEEGGSEAEQ 994
+QK + S + E ++ +E+ EEEE EE+ EEEEE E E+
Sbjct: 250 KQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 297
Score = 30.8 bits (68), Expect = 8.1
Identities = 16/34 (47%), Positives = 21/34 (61%)
Query: 961 ESLKDFCQEDLEEEENLPEEDSEEEEEGGSEAEQ 994
E +D +E+ EEEE EE+ EEEEE E E+
Sbjct: 270 EEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 40.0 bits (92), Expect = 0.013
Identities = 64/349 (18%), Positives = 136/349 (38%), Gaps = 40/349 (11%)
Query: 888 LWTGDQELELQRLFEEFRDSDDVLGHIMKNITAKRSRARIVDKLLALGLVAERRELYKKR 947
LW +QE +++ ++ RD ++ + + + K R R +K+ + E ++R
Sbjct: 340 LW--EQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRER 397
Query: 948 QKKLASSILPNGAESLKDFCQEDLEEEENLPEEDSEE----------EEEGGSEAEQVQG 997
+KK+ E++++ ++ ++EEN+ E++ +E E+ E Q Q
Sbjct: 398 EKKMREE-----EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQE 452
Query: 998 SLVLSNENLGQSLHQEGFSIPLLWLQNCLIRAAD----------DREEDGCSQAVPL--- 1044
+ E + + +W Q + D D+E+ Q +
Sbjct: 453 EKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQ 512
Query: 1045 -VPLTEENEEAMENEQFQQLLRKLGVRPPASGQE-TFWRIPAKLSPTQLRRAAASLSQPE 1102
L E+ E E ++ Q K+ QE W K+ + R + E
Sbjct: 513 DERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 572
Query: 1103 EEQKLQPELQPKVPGEQGSDEEHC---KEHRAQALRALLLAHKKKAGLAS-----PEEED 1154
EE + E + + E+ ++E +E + Q + ++K E+E+
Sbjct: 573 EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEE 632
Query: 1155 AVGKEPLKAAPKKRQLLDSDEEQEEDEGRNRAPELGAPGIQKKKRYQIE 1203
+ ++ K ++ ++ + +E+ E E + R E G ++K R Q E
Sbjct: 633 MMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681
>gi|55741661 hypothetical protein LOC57653 [Homo sapiens]
Length = 1646
Score = 39.7 bits (91), Expect = 0.018
Identities = 52/214 (24%), Positives = 89/214 (41%), Gaps = 33/214 (15%)
Query: 475 VMEYRELFLALFRKFDERCQPRSFLRDLVETTHLFLKMLERFCRSRGNLVVQNKQKKRRK 534
VMEY + L + F+R++ E +L +++ +F + + K+ K+ +
Sbjct: 749 VMEYPAIMLKELNSYSSALSQYFFVREIFEQ-NLAGEVIFKFRQPEAHEKPSQKRVKKLR 807
Query: 535 KKKKVLDQAIVSGNVPSSPEEVEAVWPALAEQLQCCAQNSELSMDSVVPFDAASEVPVEE 594
KK+ S E++ SE S+ S A S VEE
Sbjct: 808 KKQ-------------GSKEDMT---------------RSEESISSGTS-TARSVEEVEE 838
Query: 595 QRAEAMVRIQDCLLAGQAPQALTLLRSAREVWPEGDVFGSQDISPEEEIQLLKQILSAPL 654
+ + M + GQ Q + L + + EG + G +++ E E L + +
Sbjct: 839 ENDQEMESFITEEVLGQ--QKKSPLHAKMDESKEGSIQGLEEMQVEREGSLNPSLNEENV 896
Query: 655 PRQQGPEERGAEEEEEEEEEEEEELQVVQVSEKE 688
Q +E EE+E+EEEEEEE+L+ + EKE
Sbjct: 897 KGQGEKKEESEEEDEKEEEEEEEKLE-EEKEEKE 929
Score = 32.0 bits (71), Expect = 3.7
Identities = 23/98 (23%), Positives = 51/98 (52%), Gaps = 8/98 (8%)
Query: 1095 AASLSQPEEE--QKLQPELQPKVPGEQGSDEEHCK--EHRAQALRALLLAHKKKAGLASP 1150
A S+ + EEE Q+++ + +V G+Q H K E + +++ L ++ G +P
Sbjct: 830 ARSVEEVEEENDQEMESFITEEVLGQQKKSPLHAKMDESKEGSIQGLEEMQVEREGSLNP 889
Query: 1151 EEEDAVGKEPLKAAPKKRQLLDSDEEQEEDEGRNRAPE 1188
++ +E +K +K++ + ++E+EE+E + E
Sbjct: 890 ----SLNEENVKGQGEKKEESEEEDEKEEEEEEEKLEE 923
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 39.7 bits (91), Expect = 0.018
Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 8/131 (6%)
Query: 553 PEEVEAVWPALAEQ-LQCCAQNSELSMDSVVPFDAASEVPVEEQRAEAMVRIQDCLLAGQ 611
P + + VWP ++ L QN E + E P+E + V +++ +
Sbjct: 1241 PLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEP---DEQVTVEEQKETSE 1297
Query: 612 APQALTLLRSAREVWPEGDVFGSQDISPEEEIQLLKQILSAPLPRQQG----PEERGAEE 667
+ + +R EV G+ Q+ + EE ++P + + PEE EE
Sbjct: 1298 GKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEE 1357
Query: 668 EEEEEEEEEEE 678
EEEEEEEEEEE
Sbjct: 1358 EEEEEEEEEEE 1368
Score = 39.3 bits (90), Expect = 0.023
Identities = 36/131 (27%), Positives = 61/131 (46%), Gaps = 8/131 (6%)
Query: 565 EQLQCCAQNSELSMDSV--VPFDAASEVPVEEQR-----AEAMVRIQDCLLAGQAPQALT 617
E+L+ C++ +EL DS+ P ++ EE+R AE ++ C + + L+
Sbjct: 969 EKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCW-EKEEQEILS 1027
Query: 618 LLRSAREVWPEGDVFGSQDISPEEEIQLLKQILSAPLPRQQGPEERGAEEEEEEEEEEEE 677
++R+ + SPE ++ L ++ EE E+EEEEEEEEEE
Sbjct: 1028 TRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEE 1087
Query: 678 ELQVVQVSEKE 688
E + E+E
Sbjct: 1088 EEDEEEEEEEE 1098
Score = 36.6 bits (83), Expect = 0.15
Identities = 51/206 (24%), Positives = 86/206 (41%), Gaps = 28/206 (13%)
Query: 945 KKRQKKLASSILPN---GAESLKDFCQEDLEEEENLPEEDSEEEEEGGSEAEQVQGSLVL 1001
+ R+++ + + PN G + D + + EEEE EE+ EEEEEG E E+ G++
Sbjct: 1323 ENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEG--EEEEGGGNVEK 1380
Query: 1002 SNENLGQSLHQEGFSIPLLWLQNCLIRAADDREEDGCSQAVPL----VPLTEENEEAMEN 1057
+ +E P + + DD EE+ P +E++ ME+
Sbjct: 1381 DPDGAKSQEKEE----PEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMES 1436
Query: 1058 EQFQ-QLLRKLGVRPPASGQETFWRI---PAKLSPTQLRRA----AASLSQPEEEQKLQP 1109
+ + + L + + QETF + P +P L AS + +E P
Sbjct: 1437 AEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDP 1496
Query: 1110 ELQPK-----VPGEQG--SDEEHCKE 1128
E P+ PGEQ D+++ KE
Sbjct: 1497 EAVPESDEEPPPGEQAQKQDQKNSKE 1522
Score = 35.0 bits (79), Expect = 0.43
Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 8/111 (7%)
Query: 892 DQELELQRLFEEF----RDSDDVLGHIMKNITAKRSRARIVDKLLALGLVAERRELYKKR 947
+ E E +RL E+ ++ ++L +++S A++ K L E R + +R
Sbjct: 1003 EAEKEAERLMEQASCWEKEEQEILS---TRANSRQSPAKVQSKNKYLHS-PESRPVTGER 1058
Query: 948 QKKLASSILPNGAESLKDFCQEDLEEEENLPEEDSEEEEEGGSEAEQVQGS 998
+ L S + E ++ +E+ EEEE +E+ EEEEE E E +Q S
Sbjct: 1059 GQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSS 1109
Score = 33.9 bits (76), Expect = 0.96
Identities = 16/29 (55%), Positives = 21/29 (72%)
Query: 657 QQGPEERGAEEEEEEEEEEEEELQVVQVS 685
++ EE +EEEEEEEEEEEE + +Q S
Sbjct: 1081 EEEEEEEEEDEEEEEEEEEEEEEENIQSS 1109
Score = 32.0 bits (71), Expect = 3.7
Identities = 27/126 (21%), Positives = 52/126 (41%), Gaps = 2/126 (1%)
Query: 1083 PAKLSPTQLRRAAASLSQPEEEQKLQPELQPKVPGEQGSDEEHCKEHRAQALRALLLAHK 1142
P L T + + A++S+ E E + + E + +E+ RA + ++
Sbjct: 982 PDSLRWTPILISNAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQS 1041
Query: 1143 KKAGLASPEEEDAVGKEPLKAAPKKRQLLDSDEEQEEDEGRNRAPELGAPGIQKKKRYQI 1202
K L SPE G+ K +EE+EEDE E ++++ +
Sbjct: 1042 KNKYLHSPESRPVTGERGQLLELSKES--SEEEEEEEDEEEEEEEEEEEEDEEEEEEEEE 1099
Query: 1203 EDDEDD 1208
E++E++
Sbjct: 1100 EEEEEN 1105
Score = 31.2 bits (69), Expect = 6.2
Identities = 16/39 (41%), Positives = 23/39 (58%)
Query: 968 QEDLEEEENLPEEDSEEEEEGGSEAEQVQGSLVLSNENL 1006
+ED EEEE EE+ +EEEE E E+ + ++ S L
Sbjct: 1075 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRL 1113
>gi|112807226 hypothetical protein LOC91748 [Homo sapiens]
Length = 1045
Score = 39.7 bits (91), Expect = 0.018
Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 15/105 (14%)
Query: 629 GDVFGSQDISPEEEIQL----LKQILSAPLPRQQGPEERGAE---EEEEEEEEEEEELQV 681
GDV S + S +EE+++ ++ PLPR++ P E E E +E +E EEE+
Sbjct: 889 GDVDTSDEKSAQEEVEVDIKTSQKFPRVPLPRRESPSEERLEPKREVKEPRKEGEEEVPE 948
Query: 682 VQVSEKEFNFLDYLKRFACSTVVRAY--------VLLLRSYQQNS 718
+Q E++ + +R A + +L+LRS++ N+
Sbjct: 949 IQEKEEQEEGRERSRRAAAVKATQTLQANESASDILILRSHESNA 993
>gi|44890062 hypothetical protein LOC91748 [Homo sapiens]
Length = 1045
Score = 39.7 bits (91), Expect = 0.018
Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 15/105 (14%)
Query: 629 GDVFGSQDISPEEEIQL----LKQILSAPLPRQQGPEERGAE---EEEEEEEEEEEELQV 681
GDV S + S +EE+++ ++ PLPR++ P E E E +E +E EEE+
Sbjct: 889 GDVDTSDEKSAQEEVEVDIKTSQKFPRVPLPRRESPSEERLEPKREVKEPRKEGEEEVPE 948
Query: 682 VQVSEKEFNFLDYLKRFACSTVVRAY--------VLLLRSYQQNS 718
+Q E++ + +R A + +L+LRS++ N+
Sbjct: 949 IQEKEEQEEGRERSRRAAAVKATQTLQANESASDILILRSHESNA 993
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 39.3 bits (90), Expect = 0.023
Identities = 29/135 (21%), Positives = 59/135 (43%), Gaps = 2/135 (1%)
Query: 857 PRTRKQIIHHLVQMGLADSVKDFQRKGTHIVLWTGDQELELQRLFEEFRDSDDVLGHIMK 916
PR R +++ H + + +S ++ + K G ++ E+ DSD + +
Sbjct: 1296 PRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSS--EDSEDSDFQESGVSE 1353
Query: 917 NITAKRSRARIVDKLLALGLVAERRELYKKRQKKLASSILPNGAESLKDFCQEDLEEEEN 976
++ R + + E + YK+++K+ + + + K +E+ EE+E
Sbjct: 1354 EVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEE 1413
Query: 977 LPEEDSEEEEEGGSE 991
EE+ EEEEE E
Sbjct: 1414 EEEEEEEEEEEEEDE 1428
Score = 33.5 bits (75), Expect = 1.3
Identities = 37/165 (22%), Positives = 72/165 (43%), Gaps = 12/165 (7%)
Query: 1050 ENEEAMENEQFQQLLR-KLGVRPPASGQETFWRIPAKLSPTQLRRAAASLSQPEEEQKLQ 1108
++EE+ + +LLR KL V SG+E + P + + R S+ E+ Q
Sbjct: 1289 DSEESKKPRYRHRLLRHKLTVSDGESGEEKKTK-PKEHKEVKGRNRRKVSSEDSEDSDFQ 1347
Query: 1109 PELQPKVPGEQGSDEEHCKEHRAQALRALLLAH-------KKKAGLASPEEEDAVGKEPL 1161
+ V E E+ + A +A L + KK+ + E+ + K
Sbjct: 1348 ---ESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNS 1404
Query: 1162 KAAPKKRQLLDSDEEQEEDEGRNRAPELGAPGIQKKKRYQIEDDE 1206
+ ++++ + +EE+EE+E + + +PG +KK +I D+
Sbjct: 1405 EEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDD 1449
Score = 33.5 bits (75), Expect = 1.3
Identities = 15/22 (68%), Positives = 18/22 (81%)
Query: 657 QQGPEERGAEEEEEEEEEEEEE 678
++ EE+ EEEEEEEEEEEEE
Sbjct: 1405 EEEEEEKEEEEEEEEEEEEEEE 1426
Score = 33.1 bits (74), Expect = 1.6
Identities = 21/59 (35%), Positives = 29/59 (49%)
Query: 620 RSAREVWPEGDVFGSQDISPEEEIQLLKQILSAPLPRQQGPEERGAEEEEEEEEEEEEE 678
RSA++ E + + I++ + S + EE EEEEEEEEEEEEE
Sbjct: 1367 RSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEE 1425
Score = 31.6 bits (70), Expect = 4.8
Identities = 53/251 (21%), Positives = 103/251 (41%), Gaps = 51/251 (20%)
Query: 975 ENLPEEDSEEEEEGGSE------AEQVQGSLVLSNENLGQSLHQEGFSIPLLWLQNCL-- 1026
+N+P E+ + G E E+ Q ++E+L + S+P +N
Sbjct: 438 QNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETA 497
Query: 1027 --IRAADDREEDGCS--------QAVPLVPLTEENEEAMENEQFQQLLRKLGVRPPASGQ 1076
++++ D + DG S +V L +++N ++++ ++ ++L V+
Sbjct: 498 MEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVK------ 551
Query: 1077 ETFWRIPAKLSPTQLRRA-AASLSQPEEEQK---LQPELQPKVPGEQGSDEEHCKEHRAQ 1132
P LS + ++ A + Q ++ K L P+L+ G++ SD EH E+
Sbjct: 552 ----LTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEV- 606
Query: 1133 ALRALLLAHKKKAGLASPEEEDAVGKEPLKAAPKKRQL----LDSDEEQEEDEGRNRAPE 1188
+LLL EE D +K P +R + S+ ++E +E +
Sbjct: 607 ---SLLL-----------EESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQK 652
Query: 1189 LGAPGIQKKKR 1199
L P +K KR
Sbjct: 653 LSVPVRKKDKR 663
Score = 30.8 bits (68), Expect = 8.1
Identities = 14/26 (53%), Positives = 20/26 (76%)
Query: 665 AEEEEEEEEEEEEELQVVQVSEKEFN 690
+EEEEEE+EEEEEE + + E++ N
Sbjct: 1404 SEEEEEEKEEEEEEEEEEEEEEEDEN 1429
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 39.3 bits (90), Expect = 0.023
Identities = 29/135 (21%), Positives = 59/135 (43%), Gaps = 2/135 (1%)
Query: 857 PRTRKQIIHHLVQMGLADSVKDFQRKGTHIVLWTGDQELELQRLFEEFRDSDDVLGHIMK 916
PR R +++ H + + +S ++ + K G ++ E+ DSD + +
Sbjct: 1334 PRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSS--EDSEDSDFQESGVSE 1391
Query: 917 NITAKRSRARIVDKLLALGLVAERRELYKKRQKKLASSILPNGAESLKDFCQEDLEEEEN 976
++ R + + E + YK+++K+ + + + K +E+ EE+E
Sbjct: 1392 EVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEE 1451
Query: 977 LPEEDSEEEEEGGSE 991
EE+ EEEEE E
Sbjct: 1452 EEEEEEEEEEEEEDE 1466
Score = 33.5 bits (75), Expect = 1.3
Identities = 37/165 (22%), Positives = 72/165 (43%), Gaps = 12/165 (7%)
Query: 1050 ENEEAMENEQFQQLLR-KLGVRPPASGQETFWRIPAKLSPTQLRRAAASLSQPEEEQKLQ 1108
++EE+ + +LLR KL V SG+E + P + + R S+ E+ Q
Sbjct: 1327 DSEESKKPRYRHRLLRHKLTVSDGESGEEKKTK-PKEHKEVKGRNRRKVSSEDSEDSDFQ 1385
Query: 1109 PELQPKVPGEQGSDEEHCKEHRAQALRALLLAH-------KKKAGLASPEEEDAVGKEPL 1161
+ V E E+ + A +A L + KK+ + E+ + K
Sbjct: 1386 ---ESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNS 1442
Query: 1162 KAAPKKRQLLDSDEEQEEDEGRNRAPELGAPGIQKKKRYQIEDDE 1206
+ ++++ + +EE+EE+E + + +PG +KK +I D+
Sbjct: 1443 EEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDD 1487
Score = 33.5 bits (75), Expect = 1.3
Identities = 15/22 (68%), Positives = 18/22 (81%)
Query: 657 QQGPEERGAEEEEEEEEEEEEE 678
++ EE+ EEEEEEEEEEEEE
Sbjct: 1443 EEEEEEKEEEEEEEEEEEEEEE 1464
Score = 33.1 bits (74), Expect = 1.6
Identities = 21/59 (35%), Positives = 29/59 (49%)
Query: 620 RSAREVWPEGDVFGSQDISPEEEIQLLKQILSAPLPRQQGPEERGAEEEEEEEEEEEEE 678
RSA++ E + + I++ + S + EE EEEEEEEEEEEEE
Sbjct: 1405 RSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEE 1463
Score = 31.6 bits (70), Expect = 4.8
Identities = 53/251 (21%), Positives = 103/251 (41%), Gaps = 51/251 (20%)
Query: 975 ENLPEEDSEEEEEGGSE------AEQVQGSLVLSNENLGQSLHQEGFSIPLLWLQNCL-- 1026
+N+P E+ + G E E+ Q ++E+L + S+P +N
Sbjct: 476 QNVPTEEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETA 535
Query: 1027 --IRAADDREEDGCS--------QAVPLVPLTEENEEAMENEQFQQLLRKLGVRPPASGQ 1076
++++ D + DG S +V L +++N ++++ ++ ++L V+
Sbjct: 536 MEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVK------ 589
Query: 1077 ETFWRIPAKLSPTQLRRA-AASLSQPEEEQK---LQPELQPKVPGEQGSDEEHCKEHRAQ 1132
P LS + ++ A + Q ++ K L P+L+ G++ SD EH E+
Sbjct: 590 ----LTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEV- 644
Query: 1133 ALRALLLAHKKKAGLASPEEEDAVGKEPLKAAPKKRQL----LDSDEEQEEDEGRNRAPE 1188
+LLL EE D +K P +R + S+ ++E +E +
Sbjct: 645 ---SLLL-----------EESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQK 690
Query: 1189 LGAPGIQKKKR 1199
L P +K KR
Sbjct: 691 LSVPVRKKDKR 701
Score = 30.8 bits (68), Expect = 8.1
Identities = 14/26 (53%), Positives = 20/26 (76%)
Query: 665 AEEEEEEEEEEEEELQVVQVSEKEFN 690
+EEEEEE+EEEEEE + + E++ N
Sbjct: 1442 SEEEEEEKEEEEEEEEEEEEEEEDEN 1467
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 39.3 bits (90), Expect = 0.023
Identities = 80/382 (20%), Positives = 154/382 (40%), Gaps = 47/382 (12%)
Query: 825 EEEAHLRELY-----LANKDVEGQDV---VEAILAHLNTVPRTRKQIIHHLVQMGLADSV 876
E EA REL L N + D+ +E + H +T+ R +I + G +
Sbjct: 201 ELEARTRELSRTQEELMNSNQMSSDLSQKLEELQRHYSTLEEQRDHVIAS--KTGAESKI 258
Query: 877 KDFQRKGTHIVLWTGDQELELQRLFEEFRDSDDVLGHIMKNITAKRSR-------ARIVD 929
++K + ++LQ++ E ++ +DV+ H+ + + + R V
Sbjct: 259 TALEQKEQELQALIQQLSIDLQKVTAETQEKEDVITHLQEKVASLEKRLEQNLSGEEHVQ 318
Query: 930 KLLALGLVAERRELYKKRQKKLASSILPNGAESLKDFCQEDLEEEENLPEEDSEEEEEGG 989
+LL +AE + L RQ+ LA+ A + + +LE+ EE ++ +G
Sbjct: 319 ELLKEKTLAE-QNLEDTRQQLLAARSSQAKAINTLETRVRELEQTLQASEEQL-QQSKGI 376
Query: 990 SEAEQVQGSLVLSNENLGQSLHQEGFSIPLLWLQNC-----------LIRAADD-REEDG 1037
A++ Q + + + Q+ ++ +L+ RAAD E G
Sbjct: 377 VAAQETQIQELAAANQESSHVQQQALALEQQFLERTQALEAQIVALERTRAADQTTAEQG 436
Query: 1038 CSQA----VPLVPLTEENEEAMENEQFQ--QLLRKLGVRPPASGQETFWRIPAKLSPTQL 1091
Q L E E +++N QF+ +L + R S + +
Sbjct: 437 MRQLEQENAALKECRNEYERSLQNHQFELKKLKEEWSQREIVSVAMAQALEEVRKQREEF 496
Query: 1092 RRAAASLSQ--PEEEQKLQPELQPKVPGEQ-------GSDEEHCKEHRAQA-LRALLLAH 1141
++ AA+L+ E+EQ L+ + + + EQ G + + H+ QA L AL
Sbjct: 497 QQQAANLTAIIDEKEQNLREKTEVLLQKEQEILQLERGHNSALLQIHQLQAELEALRTLK 556
Query: 1142 KKKAGLASPEEEDAVGKEPLKA 1163
++A + + +E+ + PL+A
Sbjct: 557 AEEAAVVAEQEDLLRLRGPLQA 578
>gi|28274705 family with sequence similarity 9, member A [Homo
sapiens]
Length = 332
Score = 38.9 bits (89), Expect = 0.030
Identities = 30/75 (40%), Positives = 39/75 (52%), Gaps = 14/75 (18%)
Query: 659 GPEERGAEEEEEEEEEEEEELQVVQVSEKEFNFLDYLKRFACSTVVRAYVL-----LLRS 713
G E EEEEEEEEEEEEE Q+ EK+ KR+ T VR++ L LL
Sbjct: 255 GGEGEETEEEEEEEEEEEEEEQIKAFQEKQ-------KRWQQPTGVRSWRLREMKPLLEQ 307
Query: 714 YQQNSAHT--NHCIV 726
+ + T N+CI+
Sbjct: 308 LLKAAKDTKDNYCII 322
Score = 32.7 bits (73), Expect = 2.1
Identities = 29/108 (26%), Positives = 49/108 (45%), Gaps = 19/108 (17%)
Query: 896 ELQRLFEEFRDSDDVLGHIMKNITAKRSRARIVDKLLALGLVAERRELYKKRQKKLASSI 955
+L+R ++R + +L +++K A++ + ++ A AE A++
Sbjct: 160 QLKRQKRDYRHTRKLL-NVLKEYIAEKQKDDEAEEAEAAAAAAE------------AAAA 206
Query: 956 LPNGAESLKDFCQEDLEEEENLPEEDSEEEEE------GGSEAEQVQG 997
A + + ED EEEE EE+ EEEEE GG E E+ G
Sbjct: 207 AEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGG 254
>gi|19913406 DNA topoisomerase II, alpha isozyme [Homo sapiens]
Length = 1531
Score = 38.5 bits (88), Expect = 0.039
Identities = 59/281 (20%), Positives = 112/281 (39%), Gaps = 32/281 (11%)
Query: 946 KRQKKLASSILPNGAESLKDFCQEDLEEEENLPEEDSEEEEEGGSEAEQVQGSLVLSNEN 1005
K +K+L ++ G +S D + E ++ +P+E+ EE + E E+ S+ S
Sbjct: 1068 KPKKELIKVLIQRGYDS--DPVKAWKEAQQKVPDEEENEESDNEKETEK-SDSVTDSGPT 1124
Query: 1006 LGQSLHQEGFSIPLLWLQN------CLIRAADDREEDGCSQAVP-------LVPLTEENE 1052
L +PL +L C +R ++E D + P L EE E
Sbjct: 1125 FNYLL-----DMPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDLWKEDLATFIEELE 1179
Query: 1053 EAMENEQFQQLLRKLGVRPPASGQETFWR--IPAKLSPTQLRRAAASLSQPEEEQKLQPE 1110
E+ + + G A G++T +P+ + R + + E E+K + +
Sbjct: 1180 AVEAKEKQDEQVGLPGKGGKAKGKKTQMAEVLPSPRGQRVIPRITIEM-KAEAEKKNKKK 1238
Query: 1111 LQPKVPGEQGSDEEHCKEHRAQALRALLLAHKKKAGLASPEEEDAVGKEPLKAAPKKRQL 1170
+ K +GS +E E + L+ L +K+ +++ + +P+K K+
Sbjct: 1239 I--KNENTEGSPQEDGVE--LEGLKQRLEKKQKREPGTKTKKQTTLAFKPIKKGKKRNPW 1294
Query: 1171 LDSDEEQEEDEGRNRAP----ELGAPGIQKKKRYQIEDDED 1207
DS+ ++ DE P E + K ++ DED
Sbjct: 1295 SDSESDRSSDESNFDVPPRETEPRRAATKTKFTMDLDSDED 1335
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 38.5 bits (88), Expect = 0.039
Identities = 87/380 (22%), Positives = 150/380 (39%), Gaps = 68/380 (17%)
Query: 825 EEEAHLRELYLANK-DVEGQD-----VVEAILAHLNTVPRTRKQIIHHLVQMGLAD---- 874
EEE RE+ K ++E Q V+ + L + KQ + L Q L D
Sbjct: 824 EEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQL-QAQLEDYKEK 882
Query: 875 ---SVKDFQRKGTHIVLWTGDQELELQRLFEEFRDSDDVLGHIMKNITAKRSRARIVDKL 931
V D QR+ W + E L +D L ++ A+R AR+ +L
Sbjct: 883 ARREVADAQRQAKD---WASEAEKTSGGL-SRLQDEIQRLRQALQASQAERDTARLDKEL 938
Query: 932 LALGLVAERRELYKKRQKKLASSILPNGAESLKDFCQEDLEEEENLPEEDSEEEEEGGSE 991
LA L +E K++ + + G E + +L+EE+N E ++ G +
Sbjct: 939 LAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQ 998
Query: 992 AEQVQGSLV-------------LSNENLGQSL-----HQEGF-----SIPLLWLQNCLIR 1028
+Q++ L+ +S E + L EGF S+ L QN L++
Sbjct: 999 VDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSASLSQLESQNQLLQ 1058
Query: 1029 ---AADDREED-------GCSQAVPLVPLTEENEEAMENEQFQQLLRKLGV--RPPASGQ 1076
A++RE+ + V + + E+E N+Q QL ++ R +
Sbjct: 1059 ERLQAEEREKTVLQSTNRKLERKVKELSIQIEDERQHVNDQKDQLSLRVKALKRQVDEAE 1118
Query: 1077 ETFWRIPAKLSPTQLRRAAASLSQPEEEQKLQPELQPKVPGEQGSDEEHCKEHRAQALRA 1136
E R+ LR+ A + EE+ ++ +LQ ++ + K+ +A R+
Sbjct: 1119 EEIERLDG------LRKKAQ--REVEEQHEVNEQLQARIKSLE-------KDSWRKASRS 1163
Query: 1137 LLLAHKKKAGLASPEEEDAV 1156
+ K GL+S EE D+V
Sbjct: 1164 AAESALKNEGLSSDEEFDSV 1183
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
isoform b [Homo sapiens]
Length = 1176
Score = 38.1 bits (87), Expect = 0.051
Identities = 19/43 (44%), Positives = 26/43 (60%)
Query: 636 DISPEEEIQLLKQILSAPLPRQQGPEERGAEEEEEEEEEEEEE 678
D + E++ L + LS ++ EE EEEEEEEEEE+EE
Sbjct: 284 DSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEE 326
Score = 32.7 bits (73), Expect = 2.1
Identities = 16/38 (42%), Positives = 23/38 (60%)
Query: 961 ESLKDFCQEDLEEEENLPEEDSEEEEEGGSEAEQVQGS 998
E+L + E+ EEEE EE+ EEEEE E ++ G+
Sbjct: 292 EALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGN 329
Score = 31.2 bits (69), Expect = 6.2
Identities = 12/27 (44%), Positives = 21/27 (77%)
Query: 968 QEDLEEEENLPEEDSEEEEEGGSEAEQ 994
+E+ EEEE EE+ EE+EE G+++++
Sbjct: 307 EEEEEEEEEEEEEEEEEDEESGNQSDR 333
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
isoform a [Homo sapiens]
Length = 1210
Score = 38.1 bits (87), Expect = 0.051
Identities = 19/43 (44%), Positives = 26/43 (60%)
Query: 636 DISPEEEIQLLKQILSAPLPRQQGPEERGAEEEEEEEEEEEEE 678
D + E++ L + LS ++ EE EEEEEEEEEE+EE
Sbjct: 284 DSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEE 326
Score = 32.7 bits (73), Expect = 2.1
Identities = 16/38 (42%), Positives = 23/38 (60%)
Query: 961 ESLKDFCQEDLEEEENLPEEDSEEEEEGGSEAEQVQGS 998
E+L + E+ EEEE EE+ EEEEE E ++ G+
Sbjct: 292 EALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGN 329
Score = 31.2 bits (69), Expect = 6.2
Identities = 12/27 (44%), Positives = 21/27 (77%)
Query: 968 QEDLEEEENLPEEDSEEEEEGGSEAEQ 994
+E+ EEEE EE+ EE+EE G+++++
Sbjct: 307 EEEEEEEEEEEEEEEEEDEESGNQSDR 333
>gi|20336305 B-cell CLL/lymphoma 11A isoform 1 [Homo sapiens]
Length = 835
Score = 38.1 bits (87), Expect = 0.051
Identities = 20/62 (32%), Positives = 32/62 (51%)
Query: 630 DVFGSQDISPEEEIQLLKQILSAPLPRQQGPEERGAEEEEEEEEEEEEELQVVQVSEKEF 689
D+ GS + + + K L + G EE ++EEEEEEEEEEE ++ + ++
Sbjct: 454 DLVGSASSALKSVVAKFKSENDPNLIPENGDEEEEEDDEEEEEEEEEEEEELTESERVDY 513
Query: 690 NF 691
F
Sbjct: 514 GF 515
Score = 32.7 bits (73), Expect = 2.1
Identities = 16/33 (48%), Positives = 21/33 (63%)
Query: 662 ERGAEEEEEEEEEEEEELQVVQVSEKEFNFLDY 694
E G EEEEE++EEEEEE + + E +DY
Sbjct: 481 ENGDEEEEEDDEEEEEEEEEEEEELTESERVDY 513
>gi|20336307 B-cell CLL/lymphoma 11A isoform 2 [Homo sapiens]
Length = 773
Score = 38.1 bits (87), Expect = 0.051
Identities = 20/62 (32%), Positives = 32/62 (51%)
Query: 630 DVFGSQDISPEEEIQLLKQILSAPLPRQQGPEERGAEEEEEEEEEEEEELQVVQVSEKEF 689
D+ GS + + + K L + G EE ++EEEEEEEEEEE ++ + ++
Sbjct: 454 DLVGSASSALKSVVAKFKSENDPNLIPENGDEEEEEDDEEEEEEEEEEEEELTESERVDY 513
Query: 690 NF 691
F
Sbjct: 514 GF 515
Score = 32.7 bits (73), Expect = 2.1
Identities = 16/33 (48%), Positives = 21/33 (63%)
Query: 662 ERGAEEEEEEEEEEEEELQVVQVSEKEFNFLDY 694
E G EEEEE++EEEEEE + + E +DY
Sbjct: 481 ENGDEEEEEDDEEEEEEEEEEEEELTESERVDY 513
>gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sapiens]
Length = 525
Score = 38.1 bits (87), Expect = 0.051
Identities = 62/272 (22%), Positives = 110/272 (40%), Gaps = 58/272 (21%)
Query: 936 LVAERRELYKKRQKKLASSILPNGAESLKDFCQ--EDLEEEENLPEEDSEEEEEGGSEAE 993
L+ + ++ +++QKKL L G +SL+D + ++EE PE +++E+ + E E
Sbjct: 144 LIEDWKKAREEKQKKLIE--LQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWE-E 200
Query: 994 QVQGSLVLSNENLGQSLHQEGFSIPLLWLQNCLIRAADDREEDGCSQAVPLVP---LTEE 1050
Q+ + + L +E D + DG L L +
Sbjct: 201 QLAAAKAQQEQELAADAFKEL-----------------DDDMDGTVSVTELQTHPELDTD 243
Query: 1051 NEEAMENEQFQQLLRKLGVRPPASGQETFW-----RIPAKLSPTQLRRAAA-SLSQPEEE 1104
+ A+ + Q LL S + W + ++ PT L +A L++P+EE
Sbjct: 244 GDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEE 303
Query: 1105 QKLQPELQPKVPGEQGSDEEHCKEHRAQALRALLLAHKKKAGLASPEEEDA--VGKEPLK 1162
QP + P P E+ +EE +E A+ EEED+ G++P
Sbjct: 304 ---QPPV-PSSPTEEEEEEEEEEEEEAE---------------EEEEEEDSEVQGEQPKP 344
Query: 1163 AAPKKRQLLDSDEEQEE------DEGRNRAPE 1188
A+P + + +EQ + E RN+ E
Sbjct: 345 ASPAEEDKMPPYDEQTQAFIDAAQEARNKFEE 376
Score = 34.3 bits (77), Expect = 0.74
Identities = 17/36 (47%), Positives = 22/36 (61%)
Query: 653 PLPRQQGPEERGAEEEEEEEEEEEEELQVVQVSEKE 688
P+P EE EEEEEEE EEEEE + +V ++
Sbjct: 306 PVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQ 341
Score = 33.5 bits (75), Expect = 1.3
Identities = 15/34 (44%), Positives = 22/34 (64%)
Query: 655 PRQQGPEERGAEEEEEEEEEEEEELQVVQVSEKE 688
P+++ P + EEEEEEEEEEE + + E+E
Sbjct: 300 PKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEE 333
Score = 33.5 bits (75), Expect = 1.3
Identities = 15/30 (50%), Positives = 20/30 (66%)
Query: 651 SAPLPRQQGPEERGAEEEEEEEEEEEEELQ 680
S+P ++ EE EE EEEEEEE+ E+Q
Sbjct: 309 SSPTEEEEEEEEEEEEEAEEEEEEEDSEVQ 338
Score = 32.0 bits (71), Expect = 3.7
Identities = 17/37 (45%), Positives = 20/37 (54%)
Query: 650 LSAPLPRQQGPEERGAEEEEEEEEEEEEELQVVQVSE 686
L+ P Q EEEEEEEEEEEEE + + E
Sbjct: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEE 333
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 38.1 bits (87), Expect = 0.051
Identities = 52/219 (23%), Positives = 85/219 (38%), Gaps = 32/219 (14%)
Query: 916 KNITAKRSRARIVDKLLALGLVAERRELYKKRQKKLASSILP--NGAESLKDFCQEDLEE 973
++++ R RAR+++++ +G L Q LA + P NG E ++ +++ EE
Sbjct: 690 RDLSDYRERARLLNRVRRVGF---SHMLLTTPQVPLAP-VQPQANGKEEEEEEEEDEEEE 745
Query: 974 EENLPEEDSEEEEEGGSEAEQVQGSLVLSNENLGQSLHQEGFSIPLLWLQNCLIRAADDR 1033
EE+ EE+ EEEEE E E+ + + LG+ L S +R
Sbjct: 746 EEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGS----------SSEGSER 795
Query: 1034 EEDGCSQAVPLVPLTEENEEAMENEQFQQLLRKLGVRPPASGQETF----------WRIP 1083
D + P L ++ +E+ G P G +T +
Sbjct: 796 STDRSQEGAPSTLLADDQKESRGRASMAD-----GDLEPEEGSKTLVLVSPGDMKKSPVT 850
Query: 1084 AKLSP-TQLRRAAASLSQPEEEQKLQPELQPKVPGEQGS 1121
A+L+P L AA Q E Q +L PG S
Sbjct: 851 AELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSS 889
Score = 38.1 bits (87), Expect = 0.051
Identities = 20/42 (47%), Positives = 28/42 (66%), Gaps = 1/42 (2%)
Query: 648 QILSAPL-PRQQGPEERGAEEEEEEEEEEEEELQVVQVSEKE 688
Q+ AP+ P+ G EE EEE+EEEEEE+EE + + E+E
Sbjct: 719 QVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEE 760
Score = 34.3 bits (77), Expect = 0.74
Identities = 16/33 (48%), Positives = 23/33 (69%)
Query: 656 RQQGPEERGAEEEEEEEEEEEEELQVVQVSEKE 688
+++ EE EEEEEE+EEEEEE + + E+E
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEE 764
Score = 34.3 bits (77), Expect = 0.74
Identities = 16/32 (50%), Positives = 22/32 (68%)
Query: 657 QQGPEERGAEEEEEEEEEEEEELQVVQVSEKE 688
++ EE EEEEE+EEEEEEE + + E+E
Sbjct: 734 EEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEE 765
Score = 34.3 bits (77), Expect = 0.74
Identities = 16/32 (50%), Positives = 22/32 (68%)
Query: 657 QQGPEERGAEEEEEEEEEEEEELQVVQVSEKE 688
++ EE +EEEEEEEEEEEE + + E+E
Sbjct: 739 EEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 770
Score = 34.3 bits (77), Expect = 0.74
Identities = 17/28 (60%), Positives = 20/28 (71%)
Query: 661 EERGAEEEEEEEEEEEEELQVVQVSEKE 688
EE EEEEEEEEEEEEE + + E+E
Sbjct: 744 EEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 33.9 bits (76), Expect = 0.96
Identities = 16/32 (50%), Positives = 22/32 (68%)
Query: 657 QQGPEERGAEEEEEEEEEEEEELQVVQVSEKE 688
++ EE E+EEEEEEEEEEE + + E+E
Sbjct: 738 EEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEE 769
Score = 33.1 bits (74), Expect = 1.6
Identities = 16/32 (50%), Positives = 22/32 (68%)
Query: 657 QQGPEERGAEEEEEEEEEEEEELQVVQVSEKE 688
++ EE EEEE+EEEEEEEE + + E+E
Sbjct: 735 EEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEE 766
Score = 33.1 bits (74), Expect = 1.6
Identities = 16/30 (53%), Positives = 19/30 (63%)
Query: 657 QQGPEERGAEEEEEEEEEEEEELQVVQVSE 686
++ EE EEEEEEEEEEEE V + E
Sbjct: 751 EEEEEEEEEEEEEEEEEEEEEAAAAVALGE 780
>gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo
sapiens]
Length = 1925
Score = 38.1 bits (87), Expect = 0.051
Identities = 20/40 (50%), Positives = 26/40 (65%), Gaps = 7/40 (17%)
Query: 656 RQQGPEERGAEEEEE-------EEEEEEEELQVVQVSEKE 688
+++G EE+G EEEEE EEE EEEEL ++ EKE
Sbjct: 1760 KEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKE 1799
Score = 36.2 bits (82), Expect = 0.19
Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 12/114 (10%)
Query: 959 GAESLKDFCQEDLEEEENLPEEDSEEEEEGGSEAEQVQGSLVLSNENLG--------QSL 1010
G E + +E+LEEEE EE++EEEE G E E+ + E + Q
Sbjct: 1763 GEEEKGEEEEEELEEEEE-EEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPTPQPE 1821
Query: 1011 HQEGFSIPLLWLQNCLIRAADDREEDGCSQAVPLVPLTEENEEAMENEQFQQLL 1064
QE S+ W Q + +++E+D +A+ +P +EA+ Q +L
Sbjct: 1822 SQE--SMQWQWQQQLNVMVKEEQEQDE-KEAIRRLPAFANLQEALLENMIQNIL 1872
>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
sapiens]
Length = 631
Score = 37.7 bits (86), Expect = 0.067
Identities = 40/145 (27%), Positives = 60/145 (41%), Gaps = 38/145 (26%)
Query: 551 SSPEEVEAVWPALAEQLQCCAQNSELSM----------DSVVPFDAASEVPVEEQRA--- 597
SSPEE A SELS+ D P DA++E +Q +
Sbjct: 21 SSPEEQSGAVAATEASSDIDIATSELSVTVTGDGSDSRDGGFPNDASTENRSSDQESASE 80
Query: 598 ----EAMVRIQDCLLAGQAPQALTLLRSAREVWPEGDVFGSQDISPEEEIQLLKQILSAP 653
E++ + L++G++ L+ G ++ EEE + +++
Sbjct: 81 DIELESLEDFEHFLMSGESLFHYPLV-------------GEEETEREEEDEEIQE----- 122
Query: 654 LPRQQGPEERGAEEEEEEEEEEEEE 678
+ G EE EEEEEEEEEEEEE
Sbjct: 123 ---EGGEEEEEEEEEEEEEEEEEEE 144
Score = 35.8 bits (81), Expect = 0.25
Identities = 16/28 (57%), Positives = 21/28 (75%)
Query: 661 EERGAEEEEEEEEEEEEELQVVQVSEKE 688
+E G EEEEEEEEEEEEE + + E++
Sbjct: 121 QEEGGEEEEEEEEEEEEEEEEEEEEEEQ 148
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,465,870
Number of Sequences: 37866
Number of extensions: 2291819
Number of successful extensions: 34264
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 224
Number of HSP's successfully gapped in prelim test: 257
Number of HSP's that attempted gapping in prelim test: 22184
Number of HSP's gapped (non-prelim): 8995
length of query: 1208
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1094
effective length of database: 13,930,794
effective search space: 15240288636
effective search space used: 15240288636
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.