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Search of human proteins with 222080100
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222080100 BAI1-associated protein 2 isoform 4 [Homo sapiens]
(534 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222080100 BAI1-associated protein 2 isoform 4 [Homo sapiens] 1058 0.0
gi|9257199 BAI1-associated protein 2 isoform 2 [Homo sapiens] 1047 0.0
gi|5453565 BAI1-associated protein 2 isoform 3 [Homo sapiens] 1012 0.0
gi|9257197 BAI1-associated protein 2 isoform 1 [Homo sapiens] 1012 0.0
gi|32171238 BAI1-associated protein 2-like 1 [Homo sapiens] 403 e-112
gi|113205091 BAI1-associated protein 2-like 2 [Homo sapiens] 216 5e-56
gi|144226234 metastasis suppressor 1 [Homo sapiens] 70 5e-12
gi|46195763 metastasis suppressor 1-like [Homo sapiens] 60 4e-09
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 49 9e-06
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 49 9e-06
gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens] 43 8e-04
gi|7706706 sorting nexin 9 [Homo sapiens] 43 8e-04
gi|46094081 development and differentiation enhancing factor 1 [... 41 0.002
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 41 0.003
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 41 0.003
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 41 0.003
gi|5453710 LIM and SH3 protein 1 [Homo sapiens] 40 0.004
gi|148747351 protein kinase C and casein kinase substrate in neu... 40 0.004
gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo ... 40 0.005
gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo ... 40 0.005
gi|29648315 small G protein signaling modulator 3 [Homo sapiens] 39 0.012
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens] 39 0.016
gi|19924129 RAD50 homolog isoform 1 [Homo sapiens] 39 0.016
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa... 38 0.026
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa... 38 0.026
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 37 0.035
gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens] 37 0.035
gi|49640009 tetratricopeptide repeat domain 3 [Homo sapiens] 37 0.035
gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens] 37 0.045
gi|11034811 catenin (cadherin-associated protein), delta 2 (neur... 37 0.045
>gi|222080100 BAI1-associated protein 2 isoform 4 [Homo sapiens]
Length = 534
Score = 1058 bits (2735), Expect = 0.0
Identities = 534/534 (100%), Positives = 534/534 (100%)
Query: 1 MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG 60
MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG
Sbjct: 1 MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG 60
Query: 61 ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL 120
ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL
Sbjct: 61 ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL 120
Query: 121 KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS 180
KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS
Sbjct: 121 KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS 180
Query: 181 DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA 240
DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA
Sbjct: 181 DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA 240
Query: 241 VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN 300
VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN
Sbjct: 241 VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN 300
Query: 301 GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT 360
GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT
Sbjct: 301 GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT 360
Query: 361 LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK 420
LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK
Sbjct: 361 LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK 420
Query: 421 TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA 480
TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA
Sbjct: 421 TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA 480
Query: 481 QTASGFKQRPYSVAVPAFSQGLDDYGARSMSRNPFAHVQLKPTVTNDRSAPLLS 534
QTASGFKQRPYSVAVPAFSQGLDDYGARSMSRNPFAHVQLKPTVTNDRSAPLLS
Sbjct: 481 QTASGFKQRPYSVAVPAFSQGLDDYGARSMSRNPFAHVQLKPTVTNDRSAPLLS 534
>gi|9257199 BAI1-associated protein 2 isoform 2 [Homo sapiens]
Length = 552
Score = 1047 bits (2708), Expect = 0.0
Identities = 528/528 (100%), Positives = 528/528 (100%)
Query: 1 MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG 60
MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG
Sbjct: 1 MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG 60
Query: 61 ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL 120
ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL
Sbjct: 61 ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL 120
Query: 121 KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS 180
KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS
Sbjct: 121 KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS 180
Query: 181 DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA 240
DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA
Sbjct: 181 DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA 240
Query: 241 VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN 300
VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN
Sbjct: 241 VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN 300
Query: 301 GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT 360
GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT
Sbjct: 301 GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT 360
Query: 361 LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK 420
LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK
Sbjct: 361 LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK 420
Query: 421 TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA 480
TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA
Sbjct: 421 TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA 480
Query: 481 QTASGFKQRPYSVAVPAFSQGLDDYGARSMSRNPFAHVQLKPTVTNDR 528
QTASGFKQRPYSVAVPAFSQGLDDYGARSMSRNPFAHVQLKPTVTNDR
Sbjct: 481 QTASGFKQRPYSVAVPAFSQGLDDYGARSMSRNPFAHVQLKPTVTNDR 528
>gi|5453565 BAI1-associated protein 2 isoform 3 [Homo sapiens]
Length = 520
Score = 1012 bits (2616), Expect = 0.0
Identities = 511/511 (100%), Positives = 511/511 (100%)
Query: 1 MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG 60
MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG
Sbjct: 1 MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG 60
Query: 61 ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL 120
ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL
Sbjct: 61 ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL 120
Query: 121 KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS 180
KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS
Sbjct: 121 KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS 180
Query: 181 DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA 240
DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA
Sbjct: 181 DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA 240
Query: 241 VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN 300
VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN
Sbjct: 241 VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN 300
Query: 301 GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT 360
GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT
Sbjct: 301 GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT 360
Query: 361 LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK 420
LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK
Sbjct: 361 LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK 420
Query: 421 TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA 480
TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA
Sbjct: 421 TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA 480
Query: 481 QTASGFKQRPYSVAVPAFSQGLDDYGARSMS 511
QTASGFKQRPYSVAVPAFSQGLDDYGARSMS
Sbjct: 481 QTASGFKQRPYSVAVPAFSQGLDDYGARSMS 511
>gi|9257197 BAI1-associated protein 2 isoform 1 [Homo sapiens]
Length = 521
Score = 1012 bits (2616), Expect = 0.0
Identities = 511/511 (100%), Positives = 511/511 (100%)
Query: 1 MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG 60
MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG
Sbjct: 1 MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG 60
Query: 61 ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL 120
ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL
Sbjct: 61 ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL 120
Query: 121 KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS 180
KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS
Sbjct: 121 KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS 180
Query: 181 DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA 240
DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA
Sbjct: 181 DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA 240
Query: 241 VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN 300
VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN
Sbjct: 241 VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN 300
Query: 301 GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT 360
GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT
Sbjct: 301 GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT 360
Query: 361 LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK 420
LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK
Sbjct: 361 LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK 420
Query: 421 TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA 480
TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA
Sbjct: 421 TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA 480
Query: 481 QTASGFKQRPYSVAVPAFSQGLDDYGARSMS 511
QTASGFKQRPYSVAVPAFSQGLDDYGARSMS
Sbjct: 481 QTASGFKQRPYSVAVPAFSQGLDDYGARSMS 511
>gi|32171238 BAI1-associated protein 2-like 1 [Homo sapiens]
Length = 511
Score = 403 bits (1035), Expect = e-112
Identities = 220/542 (40%), Positives = 326/542 (60%), Gaps = 52/542 (9%)
Query: 7 EEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASES 66
EE++RLTE+ Y+ +MEQFNP LRN I +GKNYEKA+ + A K Y+D + K+GE+A+ S
Sbjct: 6 EEVNRLTESTYRNVMEQFNPGLRNLINLGKNYEKAVNAMILAGKAYYDGVAKIGEIATGS 65
Query: 67 QGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTE 126
S ELG VL +++ H+++ L+E K FH E++ +LE+K+ELD +Y++A LK+YQTE
Sbjct: 66 PVSTELGHVLIEISSTHKKLNESLDENFKKFHKEIIHELEKKIELDVKYMNATLKRYQTE 125
Query: 127 QRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTA 186
++K ++L+K QAELKK+R+KSQGS+N KY KE++Y++ ++++Q E++ +++DG K A
Sbjct: 126 HKNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEA 185
Query: 187 LTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQLMQQ 246
L EE+RRFCFLV+K C A + YH + ELL KLP WQ+ C D K+PE+ + ++++
Sbjct: 186 LLEEKRRFCFLVDKHCGFANHIHYYHLQSAELLNSKLPRWQETCVDAIKVPEKIMNMIEE 245
Query: 247 VASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMNGVTGPD 306
+ + P + P+ P+ +P + R +
Sbjct: 246 IKT----------------------PASTPVSGTPQASPMIERSNVVR------------ 271
Query: 307 GEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSN-TLPVRKSVTPKNSYATTENKTLPRSS 365
+DY + P + S S L D ++N S NS T+E+ +L RS
Sbjct: 272 -KDYDTLSKCSPKMPPAPSGRAYTSPLIDMFNNPATAAPNSQRVNNSTGTSEDPSLQRSV 330
Query: 366 SMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRG 425
S+A GL + +VK IF H AG N TLLSF +GD+ITLL+PE +DGW YGE + +K RG
Sbjct: 331 SVATGLNMMKKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARG 390
Query: 426 WFPFSYTRVLDSDGSDRLHM---SLQQGKSSSTGNLLDKDDLAIPPPDY------GAAS- 475
WFP SYT++L+ + ++ + + S +S ST NL + + IPPPDY GAA+
Sbjct: 391 WFPSSYTKLLEENETEAVTVPTPSPTPVRSISTVNLSENSSVVIPPPDYLECLSMGAAAD 450
Query: 476 -RAFPAQTASGFK---QRPYSVAVPAFSQGLDDYGARSMSRNPFAHVQLKPTVTNDRSAP 531
RA A+T S FK +P A P + G S NPFA V+L+PTVTNDRSAP
Sbjct: 451 RRADSARTTSTFKAPASKP-ETAAPNDANGTAKPPFLS-GENPFATVKLRPTVTNDRSAP 508
Query: 532 LL 533
++
Sbjct: 509 II 510
>gi|113205091 BAI1-associated protein 2-like 2 [Homo sapiens]
Length = 529
Score = 216 bits (549), Expect = 5e-56
Identities = 156/575 (27%), Positives = 271/575 (47%), Gaps = 100/575 (17%)
Query: 7 EEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASES 66
++ +R T +YK+IMEQFNP+L N + +G NY +A ++ AA+ YF A+ K+GE A +S
Sbjct: 6 DQFYRSTMAIYKSIMEQFNPALENLVYLGNNYLRAFHALSEAAEVYFSAIQKIGERALQS 65
Query: 67 QGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTE 126
S+ LG++L QM++ R + + LE ++++FH LL +E+ +LD +++ + + Y+ E
Sbjct: 66 PTSQILGEILVQMSDTQRHLNSDLEVVVQTFHGGLLQHMEKNTKLDMQFIKDSRQHYELE 125
Query: 127 QRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTA 186
R + L+KC +EL ++ +K + K ++++ +++ +VS+ + A
Sbjct: 126 YRHRAANLEKCMSELWRMERKRDKNVREMK---------ESVNRLHAQMQAFVSESQRAA 176
Query: 187 LTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQLMQQ 246
EE+RR+ FL EK ++ + + + +L ++ LW++ ++ S+ P RA
Sbjct: 177 ELEEKRRYRFLAEKHLLLSNTFLQFFGRARGMLQNRVLLWKEQ-SEASRSPSRA------ 229
Query: 247 VASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMNGVTGPD 306
S G P+ + P P + P ++ P R + S+P +G
Sbjct: 230 -HSPGLLGPA----------LGPPYPSGRLTPTCLDMPP---RPLGEFSSPRSRHGSGSY 275
Query: 307 GEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKTLPRSSS 366
G + A+P S P +S LP S + S + +++
Sbjct: 276 GTE-------PDARPASQLEPDRRS---------LPRTPSASSLYSGSAQSSRSNSFGER 319
Query: 367 MAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGW 426
G G RV+A+ SH+ G N TLL F GD++ +LVPEA++GW YG+ E + GW
Sbjct: 320 PGGG---GGARRVRALVSHSEGANHTLLRFSAGDVVEVLVPEAQNGWLYGKLEGSSASGW 376
Query: 427 FPFSYTRVLD-------------------------SDGSDRLHMSLQQGKSSSTGNLLDK 461
FP +Y + L+ + G++ S S S +LLD+
Sbjct: 377 FPEAYVKALEEGPVNPMTPVTPMTSMTSMSPMTPMNPGNELPSRSYPLRGSHSLDDLLDR 436
Query: 462 DDLAIPPPDY--GAASRAFPAQTASGFKQRPYSVAVPAFSQGLDDYGARSMS-------- 511
+I P +Y G + P++ S + P P S G+ +++
Sbjct: 437 PGNSIAPSEYWDGQSRSRTPSRVPS---RAPSPAPPPLPSSRRSSMGSTAVATDVKKLMS 493
Query: 512 -------------RNPFAHVQLKPTVTNDRSAPLL 533
NPFA V+L+PT+TNDRSAPL+
Sbjct: 494 SEQYPPQELFPRGTNPFATVKLRPTITNDRSAPLI 528
>gi|144226234 metastasis suppressor 1 [Homo sapiens]
Length = 755
Score = 70.1 bits (170), Expect = 5e-12
Identities = 83/379 (21%), Positives = 164/379 (43%), Gaps = 35/379 (9%)
Query: 16 VYKTIMEQFN---PSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQG-SKE 71
+++TI+ P +FI + L AA + DA K+ ++A+ ++G ++E
Sbjct: 15 LFQTIISDMKGSYPVWEDFINKAGKLQSQLRTTVVAAAAFLDAFQKVADMATNTRGGTRE 74
Query: 72 LGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKG 131
+G L +M HR I+ +L + + + L+ L++++E + + K + E +
Sbjct: 75 IGSALTRMCMRHRSIEAKLRQFSSALIDCLINPLQEQMEEWKKVANQLDKDHAKEYKKAR 134
Query: 132 DALDKCQAELKKLRKKS-QGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEE 190
+ K ++ KL+KK+ +G + Q D LQ +++K LE + AL EE
Sbjct: 135 QEIKKKSSDTLKLQKKAKKGRGDIQPQLDSALQ---DVNDKYLLLEETEKQAVRKALIEE 191
Query: 191 RRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQLMQQV--- 247
R RFC + V + + + L L + DP K+P + Q++ +
Sbjct: 192 RGRFCTFISMLRPVIEEEISMLGEITHLQTISEDL-KSLTMDPHKLPSSSEQVILDLKGS 250
Query: 248 ------------ASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQES 295
S + S++ +S +++ SD P + AQ++
Sbjct: 251 DYSWSYQTPPSSPSTTMSRKSSVCSSLNSVNSSDSRSSGSHSHSPSSHYRYRSSNLAQQA 310
Query: 296 TPIMNGVTGPDGEDYSPWADRKAAQPKSLS--PPQSQSKLSDSYSN-TLPVRKSVTPKNS 352
++ V+ D S + + A Q KS S PP++ ++LS+ +S+ +L V P +
Sbjct: 311 PVRLSSVSSHD----SGFISQDAFQSKSPSPMPPEAPNQLSNGFSHYSLSSESHVGPTGA 366
Query: 353 ----YATTENKTLPRSSSM 367
+ ++ LPR +S+
Sbjct: 367 GLFPHCLPASRLLPRVTSV 385
>gi|46195763 metastasis suppressor 1-like [Homo sapiens]
Length = 747
Score = 60.5 bits (145), Expect = 4e-09
Identities = 80/381 (20%), Positives = 149/381 (39%), Gaps = 36/381 (9%)
Query: 21 MEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQGS-KELGDVLFQM 79
M+ P +F + L AA + DA K+ ++A+ ++G+ +++G L +M
Sbjct: 22 MKSSYPIWEDFNSKATKLHSQLRTTVLAAVAFLDAFQKVADMATNTRGATRDIGSALTRM 81
Query: 80 AEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQA 139
HR I+ +L + + L+ L++++E + + K + E + + K +
Sbjct: 82 CMRHRSIETKLRQFTNALLESLINPLQERIEDWKKAANQLDKDHAKEYKRARHEIKKKSS 141
Query: 140 ELKKLRKKSQ----GSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEERRRFC 195
+ KL+KK++ G + Q D LQ +++ LE + AL EER RFC
Sbjct: 142 DTLKLQKKARKELLGKGDLQPQLDSALQ---DVNDMYLLLEETEKQAVRRALIEERGRFC 198
Query: 196 FLVEKQCAVAKNSAAYHSKGKEL--LAQKLPLWQQACADPSKIPERAVQLMQQV------ 247
+ V + L + L + A+P K+P + Q+++ +
Sbjct: 199 TFITFLQPVVNGELTMLGEITHLQGIIDDLVV---LTAEPHKLPPASEQVIKDLKGSDYS 255
Query: 248 -------------ASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQE 294
+S +++ SA S+S S P PG P +
Sbjct: 256 WSYQTPPSSPSSSSSRKSSMCSAPSSSSSAKGGGAPWPGGAQTYSPSSTCRYRSLAQPAT 315
Query: 295 STPIMNGVTGPDGEDYSPWADRKAAQPKSLSPPQ--SQSKLSDSYSNTLPVRKSVTPKNS 352
+T ++ V+ D S D ++P S P SQ S + S +SV+ +S
Sbjct: 316 TTARLSSVSSHDSGFVS--QDATYSKPPSPMPSDITSQKSSSSASSEASETCQSVSECSS 373
Query: 353 YATTENKTLPRSSSMAAGLER 373
+ +K A L+R
Sbjct: 374 PTSDWSKVGSHEQPSGATLQR 394
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 49.3 bits (116), Expect = 9e-06
Identities = 93/435 (21%), Positives = 177/435 (40%), Gaps = 83/435 (19%)
Query: 78 QMAEVHRQIQNQLEEMLKSFHNEL--LTQLEQKVELDSRYLSAALKKYQTEQRSKGDALD 135
Q+ EV ++ +++L+E + F+N+L L ++ K +L + A + Q EQ K L+
Sbjct: 585 QLDEVEKETRSKLQE-IDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELE 643
Query: 136 KCQAE------------LKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGY 183
K + E L+ ++++ + + + + +++L+ +++ K GE G
Sbjct: 644 KQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGE-----EKGK 698
Query: 184 KTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQL 243
+ A +++ F ++ A A + + A+K PL A + + RA+
Sbjct: 699 QEA--QDKLGRLFHQHQEPAKPAVQAPWST------AEKGPLTISAQENVKVVYYRALYP 750
Query: 244 MQQVASNGATL-PSALSASKSNLVISD-------------------PIPGAKPLP---VP 280
+ + + T+ P + K V P A+ +P VP
Sbjct: 751 FESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKIPENEVP 810
Query: 281 PELAPFVGRMSAQ------ESTPIMNGVTGPDGEDY-SPWADRKAAQPKSLSPPQ----- 328
+ P SA TP VT + + WAD + P S +
Sbjct: 811 APVKPVTDSTSAPAPKLALRETPAPLAVTSSEPSTTPNNWADFSSTWPTSTNEKPETDNW 870
Query: 329 ----SQSKLSDSYSNTLPVRKSVTPKNSYATTENKTLPRSSSMAAGLERNGRMRVKAIFS 384
+Q L+ + L R + TP + ++ + L + + ++ +A++
Sbjct: 871 DAWAAQPSLTVPSAGQLRQRSAFTPATATGSSPSPVLGQGEKVEG-------LQAQALYP 923
Query: 385 -HAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDSDGSDRL 443
A DN L+F + D+IT+L E +D W +GE + K GWFP SY +++ G R
Sbjct: 924 WRAKKDNH--LNFNKNDVITVL--EQQDMWWFGEVQGQK--GWFPKSYVKLI--SGPIRK 975
Query: 444 HMSLQQGKSSSTGNL 458
S+ G S S +L
Sbjct: 976 STSMDSGSSESPASL 990
Score = 40.0 bits (92), Expect = 0.005
Identities = 37/124 (29%), Positives = 65/124 (52%), Gaps = 16/124 (12%)
Query: 342 PVRKSVTPKNSYATTENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDL 401
P+RKS T +S ++ +L R +S AA +G + A++++ + + L +F++GD+
Sbjct: 972 PIRKS-TSMDSGSSESPASLKRVASPAAKPVVSGEEFI-AMYTYESSEQGDL-TFQQGDV 1028
Query: 402 ITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDK 461
I L+ + D W +K G FP +Y R+ DS+GS G + TG+L K
Sbjct: 1029 I-LVTKKDGDWWTGTVGDKA---GVFPSNYVRLKDSEGS---------GTAGKTGSLGKK 1075
Query: 462 DDLA 465
++A
Sbjct: 1076 PEIA 1079
Score = 31.6 bits (70), Expect = 1.9
Identities = 33/140 (23%), Positives = 66/140 (47%), Gaps = 10/140 (7%)
Query: 57 VKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLK-SFHNELLTQLEQKVE---LD 112
+++ E+ Q +E +L ++ + + +QL+++ + S H + L L++ +E L
Sbjct: 519 LRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELA 578
Query: 113 SRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQ 172
++L L + + E RSK +D +LK+LR + + QK E + + KQ
Sbjct: 579 RQHLRDQLDEVEKETRSKLQEIDIFNNQLKELR-EIHNKQQLQKQKSMEAERL-----KQ 632
Query: 173 GELENYVSDGYKTALTEERR 192
E E + + K +RR
Sbjct: 633 KEQERKIIELEKQKEEAQRR 652
Score = 29.6 bits (65), Expect = 7.2
Identities = 33/146 (22%), Positives = 72/146 (49%), Gaps = 11/146 (7%)
Query: 56 LVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRY 115
L K + E Q ++ + AE R+ + + +E + EL QLE++ EL+ +
Sbjct: 365 LEKRRQALLEQQRKEQERLAQLERAEQERK-ERERQEQERKRQLELEKQLEKQRELERQR 423
Query: 116 LSAALKKYQTEQRSKGDALDKCQAELKKLRKK---SQGSKNPQ-----KYSDKELQY-ID 166
K+ + + +K + + Q E ++ R++ +Q +K + K K L++ ++
Sbjct: 424 EEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELE 483
Query: 167 AISNKQGELENYVSDGYKTALTEERR 192
A+++K+ +LE + D + LT +R+
Sbjct: 484 ALNDKKHQLEGKLQD-IRCRLTTQRQ 508
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 49.3 bits (116), Expect = 9e-06
Identities = 93/435 (21%), Positives = 177/435 (40%), Gaps = 83/435 (19%)
Query: 78 QMAEVHRQIQNQLEEMLKSFHNEL--LTQLEQKVELDSRYLSAALKKYQTEQRSKGDALD 135
Q+ EV ++ +++L+E + F+N+L L ++ K +L + A + Q EQ K L+
Sbjct: 585 QLDEVEKETRSKLQE-IDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELE 643
Query: 136 KCQAE------------LKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGY 183
K + E L+ ++++ + + + + +++L+ +++ K GE G
Sbjct: 644 KQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGE-----EKGK 698
Query: 184 KTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQL 243
+ A +++ F ++ A A + + A+K PL A + + RA+
Sbjct: 699 QEA--QDKLGRLFHQHQEPAKPAVQAPWST------AEKGPLTISAQENVKVVYYRALYP 750
Query: 244 MQQVASNGATL-PSALSASKSNLVISD-------------------PIPGAKPLP---VP 280
+ + + T+ P + K V P A+ +P VP
Sbjct: 751 FESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKIPENEVP 810
Query: 281 PELAPFVGRMSAQ------ESTPIMNGVTGPDGEDY-SPWADRKAAQPKSLSPPQ----- 328
+ P SA TP VT + + WAD + P S +
Sbjct: 811 APVKPVTDSTSAPAPKLALRETPAPLAVTSSEPSTTPNNWADFSSTWPTSTNEKPETDNW 870
Query: 329 ----SQSKLSDSYSNTLPVRKSVTPKNSYATTENKTLPRSSSMAAGLERNGRMRVKAIFS 384
+Q L+ + L R + TP + ++ + L + + ++ +A++
Sbjct: 871 DAWAAQPSLTVPSAGQLRQRSAFTPATATGSSPSPVLGQGEKVEG-------LQAQALYP 923
Query: 385 -HAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDSDGSDRL 443
A DN L+F + D+IT+L E +D W +GE + K GWFP SY +++ G R
Sbjct: 924 WRAKKDNH--LNFNKNDVITVL--EQQDMWWFGEVQGQK--GWFPKSYVKLI--SGPIRK 975
Query: 444 HMSLQQGKSSSTGNL 458
S+ G S S +L
Sbjct: 976 STSMDSGSSESPASL 990
Score = 40.0 bits (92), Expect = 0.005
Identities = 37/124 (29%), Positives = 65/124 (52%), Gaps = 16/124 (12%)
Query: 342 PVRKSVTPKNSYATTENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDL 401
P+RKS T +S ++ +L R +S AA +G + A++++ + + L +F++GD+
Sbjct: 972 PIRKS-TSMDSGSSESPASLKRVASPAAKPVVSGEEFI-AMYTYESSEQGDL-TFQQGDV 1028
Query: 402 ITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDK 461
I L+ + D W +K G FP +Y R+ DS+GS G + TG+L K
Sbjct: 1029 I-LVTKKDGDWWTGTVGDKA---GVFPSNYVRLKDSEGS---------GTAGKTGSLGKK 1075
Query: 462 DDLA 465
++A
Sbjct: 1076 PEIA 1079
Score = 31.6 bits (70), Expect = 1.9
Identities = 33/140 (23%), Positives = 66/140 (47%), Gaps = 10/140 (7%)
Query: 57 VKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLK-SFHNELLTQLEQKVE---LD 112
+++ E+ Q +E +L ++ + + +QL+++ + S H + L L++ +E L
Sbjct: 519 LRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELA 578
Query: 113 SRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQ 172
++L L + + E RSK +D +LK+LR + + QK E + + KQ
Sbjct: 579 RQHLRDQLDEVEKETRSKLQEIDIFNNQLKELR-EIHNKQQLQKQKSMEAERL-----KQ 632
Query: 173 GELENYVSDGYKTALTEERR 192
E E + + K +RR
Sbjct: 633 KEQERKIIELEKQKEEAQRR 652
Score = 29.6 bits (65), Expect = 7.2
Identities = 33/146 (22%), Positives = 72/146 (49%), Gaps = 11/146 (7%)
Query: 56 LVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRY 115
L K + E Q ++ + AE R+ + + +E + EL QLE++ EL+ +
Sbjct: 365 LEKRRQALLEQQRKEQERLAQLERAEQERK-ERERQEQERKRQLELEKQLEKQRELERQR 423
Query: 116 LSAALKKYQTEQRSKGDALDKCQAELKKLRKK---SQGSKNPQ-----KYSDKELQY-ID 166
K+ + + +K + + Q E ++ R++ +Q +K + K K L++ ++
Sbjct: 424 EEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELE 483
Query: 167 AISNKQGELENYVSDGYKTALTEERR 192
A+++K+ +LE + D + LT +R+
Sbjct: 484 ALNDKKHQLEGKLQD-IRCRLTTQRQ 508
>gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens]
Length = 476
Score = 42.7 bits (99), Expect = 8e-04
Identities = 25/63 (39%), Positives = 36/63 (57%), Gaps = 4/63 (6%)
Query: 378 RVKAIFSHAAGDNSTLLSFKEGDLITLL-VPEARDGWHYGESEKTKMRGWFPFSYTRVLD 436
R + ++ + + L F G+LITLL VP+ GW GE E +RGWFP SY ++L+
Sbjct: 5 RCRTLYPFSGERHGQGLRFAAGELITLLQVPDG--GWWEGEKEDG-LRGWFPASYVQLLE 61
Query: 437 SDG 439
G
Sbjct: 62 KPG 64
>gi|7706706 sorting nexin 9 [Homo sapiens]
Length = 595
Score = 42.7 bits (99), Expect = 8e-04
Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Query: 378 RVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDS 437
+ + ++ AA + L+ EG++IT+ P+ GW G + K + RG P Y +L S
Sbjct: 4 KARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGE-RGLVPTDYVEILPS 62
Query: 438 DGSDR 442
DG D+
Sbjct: 63 DGKDQ 67
>gi|46094081 development and differentiation enhancing factor 1 [Homo
sapiens]
Length = 1129
Score = 41.2 bits (95), Expect = 0.002
Identities = 37/166 (22%), Positives = 64/166 (38%), Gaps = 20/166 (12%)
Query: 270 PIPGAKPLPVPPELAPFVGRMSAQESTPIMNGVTGPDGEDYSPWADRKAAQPKSLSPPQS 329
P P K LP P+L + + + +P KA QP ++
Sbjct: 982 PKPQMKDLPPKPQLGDLLAKSQTGDVSP-------------------KAQQPSEVTLKSH 1022
Query: 330 QSKLSDSYSNTLPVRKSVTPKNSYATTENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGD 389
LS + + ++K + ++ T P +N RVK I+ A D
Sbjct: 1023 PLDLSPNVQSRDAIQKQASEDSNDLTPTLPETPVPLPRKINTGKNKVRRVKTIYDCQA-D 1081
Query: 390 NSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVL 435
N L+F EG++I + E ++ W + + +G FP S+ +L
Sbjct: 1082 NDDELTFIEGEVIIVTGEEDQEWWIGHIEGQPERKGVFPVSFVHIL 1127
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 40.8 bits (94), Expect = 0.003
Identities = 31/137 (22%), Positives = 59/137 (43%), Gaps = 12/137 (8%)
Query: 307 GEDYSPWADRKAAQPKSLSPPQSQSKL-----SDSYSNTLPVRKSVTPKNSYATTENKTL 361
GE+Y + +P L+ + + L + ++ ++ R + P N + ++
Sbjct: 956 GEEYIALYPYSSVEPGDLTFTEGEEILVTQKDGEWWTGSIGDRSGIFPSNYVKPKDQESF 1015
Query: 362 PRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESE-- 419
+S A N + + + S S LS G LI L++ + GW GE +
Sbjct: 1016 GSASKSGAS---NKKPEIAQVTSAYVASGSEQLSLAPGQLI-LILKKNTSGWWQGELQAR 1071
Query: 420 -KTKMRGWFPFSYTRVL 435
K + +GWFP S+ ++L
Sbjct: 1072 GKKRQKGWFPASHVKLL 1088
Score = 39.7 bits (91), Expect = 0.007
Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 9/123 (7%)
Query: 314 ADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKTLPRSSSMAAGLER 373
A +++P S + P S + + + L V S K+++ T + P S S G +
Sbjct: 813 ATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVS---PGSVSPIHGQGQ 869
Query: 374 N-GRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYT 432
++ +A+ S A ++ L +F + D+IT+L E ++ W +GE RGWFP SY
Sbjct: 870 VVENLKAQALCSWTAKKDNHL-NFSKHDIITVL--EQQENWWFGEVHGG--RGWFPKSYV 924
Query: 433 RVL 435
+++
Sbjct: 925 KII 927
Score = 33.5 bits (75), Expect = 0.50
Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 5/72 (6%)
Query: 378 RVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRV-LD 436
+V A++ +AA +N LSF +G LI ++ + D W + E + G FP +Y ++ D
Sbjct: 1104 QVIAMYDYAA-NNEDELSFSKGQLINVMNKDDPDWW---QGEINGVTGLFPSNYVKMTTD 1159
Query: 437 SDGSDRLHMSLQ 448
SD S + LQ
Sbjct: 1160 SDPSQQWCADLQ 1171
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 40.8 bits (94), Expect = 0.003
Identities = 31/137 (22%), Positives = 59/137 (43%), Gaps = 12/137 (8%)
Query: 307 GEDYSPWADRKAAQPKSLSPPQSQSKL-----SDSYSNTLPVRKSVTPKNSYATTENKTL 361
GE+Y + +P L+ + + L + ++ ++ R + P N + ++
Sbjct: 983 GEEYIALYPYSSVEPGDLTFTEGEEILVTQKDGEWWTGSIGDRSGIFPSNYVKPKDQESF 1042
Query: 362 PRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESE-- 419
+S A N + + + S S LS G LI L++ + GW GE +
Sbjct: 1043 GSASKSGAS---NKKPEIAQVTSAYVASGSEQLSLAPGQLI-LILKKNTSGWWQGELQAR 1098
Query: 420 -KTKMRGWFPFSYTRVL 435
K + +GWFP S+ ++L
Sbjct: 1099 GKKRQKGWFPASHVKLL 1115
Score = 39.7 bits (91), Expect = 0.007
Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 9/123 (7%)
Query: 314 ADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKTLPRSSSMAAGLER 373
A +++P S + P S + + + L V S K+++ T + P S S G +
Sbjct: 840 ATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVS---PGSVSPIHGQGQ 896
Query: 374 N-GRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYT 432
++ +A+ S A ++ L +F + D+IT+L E ++ W +GE RGWFP SY
Sbjct: 897 VVENLKAQALCSWTAKKDNHL-NFSKHDIITVL--EQQENWWFGEVHGG--RGWFPKSYV 951
Query: 433 RVL 435
+++
Sbjct: 952 KII 954
Score = 33.5 bits (75), Expect = 0.50
Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 5/72 (6%)
Query: 378 RVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRV-LD 436
+V A++ +AA +N LSF +G LI ++ + D W + E + G FP +Y ++ D
Sbjct: 1131 QVIAMYDYAA-NNEDELSFSKGQLINVMNKDDPDWW---QGEINGVTGLFPSNYVKMTTD 1186
Query: 437 SDGSDRLHMSLQ 448
SD S + LQ
Sbjct: 1187 SDPSQQWCADLQ 1198
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 40.8 bits (94), Expect = 0.003
Identities = 31/137 (22%), Positives = 59/137 (43%), Gaps = 12/137 (8%)
Query: 307 GEDYSPWADRKAAQPKSLSPPQSQSKL-----SDSYSNTLPVRKSVTPKNSYATTENKTL 361
GE+Y + +P L+ + + L + ++ ++ R + P N + ++
Sbjct: 983 GEEYIALYPYSSVEPGDLTFTEGEEILVTQKDGEWWTGSIGDRSGIFPSNYVKPKDQESF 1042
Query: 362 PRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESE-- 419
+S A N + + + S S LS G LI L++ + GW GE +
Sbjct: 1043 GSASKSGAS---NKKPEIAQVTSAYVASGSEQLSLAPGQLI-LILKKNTSGWWQGELQAR 1098
Query: 420 -KTKMRGWFPFSYTRVL 435
K + +GWFP S+ ++L
Sbjct: 1099 GKKRQKGWFPASHVKLL 1115
Score = 39.7 bits (91), Expect = 0.007
Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 9/123 (7%)
Query: 314 ADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKTLPRSSSMAAGLER 373
A +++P S + P S + + + L V S K+++ T + P S S G +
Sbjct: 840 ATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVS---PGSVSPIHGQGQ 896
Query: 374 N-GRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYT 432
++ +A+ S A ++ L +F + D+IT+L E ++ W +GE RGWFP SY
Sbjct: 897 VVENLKAQALCSWTAKKDNHL-NFSKHDIITVL--EQQENWWFGEVHGG--RGWFPKSYV 951
Query: 433 RVL 435
+++
Sbjct: 952 KII 954
Score = 33.5 bits (75), Expect = 0.50
Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 5/72 (6%)
Query: 378 RVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRV-LD 436
+V A++ +AA +N LSF +G LI ++ + D W + E + G FP +Y ++ D
Sbjct: 1131 QVIAMYDYAA-NNEDELSFSKGQLINVMNKDDPDWW---QGEINGVTGLFPSNYVKMTTD 1186
Query: 437 SDGSDRLHMSLQ 448
SD S + LQ
Sbjct: 1187 SDPSQQWCADLQ 1198
>gi|5453710 LIM and SH3 protein 1 [Homo sapiens]
Length = 261
Score = 40.4 bits (93), Expect = 0.004
Identities = 21/61 (34%), Positives = 34/61 (55%), Gaps = 2/61 (3%)
Query: 375 GRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRV 434
G R +A++ ++A D + SF++GD I + V + DGW YG E+T G P +Y
Sbjct: 203 GGKRYRAVYDYSAADEDEV-SFQDGDTI-VNVQQIDDGWMYGTVERTGDTGMLPANYVEA 260
Query: 435 L 435
+
Sbjct: 261 I 261
>gi|148747351 protein kinase C and casein kinase substrate in
neurons 2 [Homo sapiens]
Length = 486
Score = 40.4 bits (93), Expect = 0.004
Identities = 80/356 (22%), Positives = 135/356 (37%), Gaps = 61/356 (17%)
Query: 106 EQKVELDSRYLSAALKKYQTEQRSK-GDALDKCQAELKKLRKKSQGS------------- 151
E+K+ + S A EQ K D ++KC+ ++ K ++K + S
Sbjct: 165 EEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYME 224
Query: 152 ------KNPQKYSDKELQYI-DAISNKQGELENYVSDGYKTAL--TEERRRFCFLVEKQC 202
+ Q++ +K L++ + + Q L+ GYK E+ R VE
Sbjct: 225 NMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVED-- 282
Query: 203 AVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQLMQQVASNGATLPSALSASK 262
+ A H G +A P +++ AD ++ R + + A++G TL
Sbjct: 283 --LRWFRANHGPG---MAMNWPQFEEWSADLNRTLSRREK---KKATDGVTLTGINQTGD 334
Query: 263 SNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMNGVTGPDGEDYSPWADRKAAQPK 322
+L P + L VP P S P + G S D KA
Sbjct: 335 QSL----PSKPSSTLNVPSN--PAQSAQSQSSYNPFED--EDDTGSTVSEKDDTKAKNVS 386
Query: 323 SLSPPQSQ-SKLSDSYSNTLPVRKSVTPKNSYATTE--NKTLPRSSSMAAGLERNGRMRV 379
S QS + SD SN N +++T+ + P +G E +RV
Sbjct: 387 SYEKTQSYPTDWSDDESN-----------NPFSSTDANGDSNPFDDDATSGTE----VRV 431
Query: 380 KAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVL 435
+A++ + G LSFK GD +T + E GW G + ++ G +P +Y +
Sbjct: 432 RALYDYE-GQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQV-GLYPANYVEAI 485
>gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo
sapiens]
Length = 628
Score = 40.0 bits (92), Expect = 0.005
Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 8/99 (8%)
Query: 341 LPVRKSVTPKNSYATTENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGD 400
LPV K++ K T P SS + K IF + A N L+ KEGD
Sbjct: 201 LPVEKTIGKKLPATTAT----PDSSKTEMDSRTKSKDYCKVIFPYEA-QNDDELTIKEGD 255
Query: 401 LITLLVPEARD-GWHYGESEKTKMRGWFPFSYTRVLDSD 438
++TL+ + D GW E E RG FP ++ ++L D
Sbjct: 256 IVTLINKDCIDVGW--WEGELNGRRGVFPDNFVKLLPPD 292
>gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo
sapiens]
Length = 665
Score = 40.0 bits (92), Expect = 0.005
Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 8/99 (8%)
Query: 341 LPVRKSVTPKNSYATTENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGD 400
LPV K++ K T P SS + K IF + A N L+ KEGD
Sbjct: 238 LPVEKTIGKKLPATTAT----PDSSKTEMDSRTKSKDYCKVIFPYEA-QNDDELTIKEGD 292
Query: 401 LITLLVPEARD-GWHYGESEKTKMRGWFPFSYTRVLDSD 438
++TL+ + D GW E E RG FP ++ ++L D
Sbjct: 293 IVTLINKDCIDVGW--WEGELNGRRGVFPDNFVKLLPPD 329
>gi|29648315 small G protein signaling modulator 3 [Homo sapiens]
Length = 749
Score = 38.9 bits (89), Expect = 0.012
Identities = 34/134 (25%), Positives = 57/134 (42%), Gaps = 13/134 (9%)
Query: 307 GEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKN-SYATTENKTLP--- 362
GED D +A + K++ + + L ++ + PKN S T + ++
Sbjct: 414 GED-----DLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDYSMESHQ 468
Query: 363 RSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTK 422
R R+ R R KA+ D+ L F++ D+IT++ + W E
Sbjct: 469 RDHENYVACSRSHRRRAKALLDFERHDDDEL-GFRKNDIITIVSQKDEHCW---VGELNG 524
Query: 423 MRGWFPFSYTRVLD 436
+RGWFP + VLD
Sbjct: 525 LRGWFPAKFVEVLD 538
>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
Length = 1173
Score = 38.5 bits (88), Expect = 0.016
Identities = 59/244 (24%), Positives = 106/244 (43%), Gaps = 37/244 (15%)
Query: 19 TIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQGSKELGDVLFQ 78
TIME+F L K+ E+ +A +G D + ++ E Q + D +
Sbjct: 654 TIMERFQMEL-------KDVERKIAQQAAKLQG-IDLDRTVQQVNQEKQEKQHKLDTVSS 705
Query: 79 MAEVHRQ-IQNQLEEM--LKSFHNELLT---------QLEQKVELDSRYLSAALKKYQTE 126
E++R+ IQ+Q E++ LKS NEL + Q Q++E + LS ++ E
Sbjct: 706 KIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEEQTVELSTEVQSLYRE 765
Query: 127 QRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQ-----YIDAISNKQG---ELENY 178
+ + + + L+K +++ + N + S+K Q + + N G ++ENY
Sbjct: 766 IKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKLNDIKEKVKNIHGYMKDIENY 825
Query: 179 VSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPE 238
+ DG ++ E +A+ S K KE + + + L +Q D KI E
Sbjct: 826 IQDGKDDYKKQKE------TELNKVIAQLSEC--EKHKEKINEDMRLMRQD-IDTQKIQE 876
Query: 239 RAVQ 242
R +Q
Sbjct: 877 RWLQ 880
>gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]
Length = 1312
Score = 38.5 bits (88), Expect = 0.016
Identities = 59/244 (24%), Positives = 106/244 (43%), Gaps = 37/244 (15%)
Query: 19 TIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQGSKELGDVLFQ 78
TIME+F L K+ E+ +A +G D + ++ E Q + D +
Sbjct: 793 TIMERFQMEL-------KDVERKIAQQAAKLQG-IDLDRTVQQVNQEKQEKQHKLDTVSS 844
Query: 79 MAEVHRQ-IQNQLEEM--LKSFHNELLT---------QLEQKVELDSRYLSAALKKYQTE 126
E++R+ IQ+Q E++ LKS NEL + Q Q++E + LS ++ E
Sbjct: 845 KIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEEQTVELSTEVQSLYRE 904
Query: 127 QRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQ-----YIDAISNKQG---ELENY 178
+ + + + L+K +++ + N + S+K Q + + N G ++ENY
Sbjct: 905 IKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKLNDIKEKVKNIHGYMKDIENY 964
Query: 179 VSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPE 238
+ DG ++ E +A+ S K KE + + + L +Q D KI E
Sbjct: 965 IQDGKDDYKKQKE------TELNKVIAQLSEC--EKHKEKINEDMRLMRQD-IDTQKIQE 1015
Query: 239 RAVQ 242
R +Q
Sbjct: 1016 RWLQ 1019
>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
sapiens]
Length = 1323
Score = 37.7 bits (86), Expect = 0.026
Identities = 51/217 (23%), Positives = 95/217 (43%), Gaps = 30/217 (13%)
Query: 85 QIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKL 144
++Q +E ++ + L Q +++ E R L A +K EQ+ + L++ Q K+L
Sbjct: 356 RLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKEL 415
Query: 145 RKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEERRRFCFLVEKQCAV 204
RK Q + +++ +++++ + + E E YK EE+R+ E+
Sbjct: 416 RK--QQEREQRRHYEEQMRREEERRRAEHEQE------YKRKQLEEQRQ----AERLQRQ 463
Query: 205 AKNSAAY-----HSKGKELLAQKLPLWQ-QACADPSKIPERAVQLMQQVASNGATLPSAL 258
K Y H + ++ +K PL+ + PS+ P A ++ ++ N + P A+
Sbjct: 464 LKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEERSRLNRQSSP-AM 522
Query: 259 SASKSNLVISDP----------IPGAKPLPVPPELAP 285
+N ISDP I G +P PP L P
Sbjct: 523 PHKVANR-ISDPNLPPRSESFSISGVQPARTPPMLRP 558
>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
sapiens]
Length = 1331
Score = 37.7 bits (86), Expect = 0.026
Identities = 51/217 (23%), Positives = 95/217 (43%), Gaps = 30/217 (13%)
Query: 85 QIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKL 144
++Q +E ++ + L Q +++ E R L A +K EQ+ + L++ Q K+L
Sbjct: 356 RLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKEL 415
Query: 145 RKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEERRRFCFLVEKQCAV 204
RK Q + +++ +++++ + + E E YK EE+R+ E+
Sbjct: 416 RK--QQEREQRRHYEEQMRREEERRRAEHEQE------YKRKQLEEQRQ----AERLQRQ 463
Query: 205 AKNSAAY-----HSKGKELLAQKLPLWQ-QACADPSKIPERAVQLMQQVASNGATLPSAL 258
K Y H + ++ +K PL+ + PS+ P A ++ ++ N + P A+
Sbjct: 464 LKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEERSRLNRQSSP-AM 522
Query: 259 SASKSNLVISDP----------IPGAKPLPVPPELAP 285
+N ISDP I G +P PP L P
Sbjct: 523 PHKVANR-ISDPNLPPRSESFSISGVQPARTPPMLRP 558
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 37.4 bits (85), Expect = 0.035
Identities = 48/218 (22%), Positives = 90/218 (41%), Gaps = 21/218 (9%)
Query: 61 ELASESQGSKELGDVLFQMAEVHRQIQN---------QLEEMLKSFHNELLTQLEQKVEL 111
E AS ++ K+ D+ ++ E+ +++ +L + ++ +L LE+
Sbjct: 1128 ERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQ 1187
Query: 112 DSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNK 171
++A KK+ G+ +D Q +KL K+ K +D +AIS
Sbjct: 1188 HEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELK---METDDLSSNAEAISKA 1244
Query: 172 QG-------ELENYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLP 224
+G LE+ VS+ KT E++R L ++ + + Y + E A
Sbjct: 1245 KGNLEKMCRSLEDQVSE-LKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQ 1303
Query: 225 LWQQACADPSKIPERAVQLMQQVASNGATLPSALSASK 262
L + A +I E QL ++ + A L AL +S+
Sbjct: 1304 LSRSKQASTQQIEELKHQLEEETKAKNA-LAHALQSSR 1340
Score = 29.3 bits (64), Expect = 9.4
Identities = 24/112 (21%), Positives = 54/112 (48%), Gaps = 7/112 (6%)
Query: 76 LFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKK------YQTEQRS 129
L + AE +++ EE K+ +EL ++ EL+ + ++ +K Q+E S
Sbjct: 842 LLKSAETEKEMATMKEEFQKT-KDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADS 900
Query: 130 KGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSD 181
DA ++C+ +K + K + +++E + ++ K+ +LE+ S+
Sbjct: 901 LADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSE 952
>gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens]
Length = 2025
Score = 37.4 bits (85), Expect = 0.035
Identities = 28/128 (21%), Positives = 60/128 (46%), Gaps = 28/128 (21%)
Query: 83 HRQIQNQLEEMLKSFHNELLTQLEQ------------------KVELD--SRYLSAALKK 122
H+ +Q+QL+E+ +++ L LE+ K ELD + L +KK
Sbjct: 1499 HQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKK 1558
Query: 123 YQTEQRSKGDALDKCQAELKKL--------RKKSQGSKNPQKYSDKELQYIDAISNKQGE 174
+Q E++ + L + ++KK+ +K K + + D+ L+ + ++N++ +
Sbjct: 1559 WQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMK 1618
Query: 175 LENYVSDG 182
+E Y+ G
Sbjct: 1619 IEEYIKKG 1626
>gi|49640009 tetratricopeptide repeat domain 3 [Homo sapiens]
Length = 2025
Score = 37.4 bits (85), Expect = 0.035
Identities = 28/128 (21%), Positives = 60/128 (46%), Gaps = 28/128 (21%)
Query: 83 HRQIQNQLEEMLKSFHNELLTQLEQ------------------KVELD--SRYLSAALKK 122
H+ +Q+QL+E+ +++ L LE+ K ELD + L +KK
Sbjct: 1499 HQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKK 1558
Query: 123 YQTEQRSKGDALDKCQAELKKL--------RKKSQGSKNPQKYSDKELQYIDAISNKQGE 174
+Q E++ + L + ++KK+ +K K + + D+ L+ + ++N++ +
Sbjct: 1559 WQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMK 1618
Query: 175 LENYVSDG 182
+E Y+ G
Sbjct: 1619 IEEYIKKG 1626
>gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens]
Length = 845
Score = 37.0 bits (84), Expect = 0.045
Identities = 22/52 (42%), Positives = 28/52 (53%), Gaps = 3/52 (5%)
Query: 380 KAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSY 431
KA + A D S L S KEGD+I +L + + GW GE GWFP +Y
Sbjct: 788 KARYDFCARDRSEL-SLKEGDIIKILNKKGQQGWWRGEIYGRV--GWFPANY 836
Score = 31.6 bits (70), Expect = 1.9
Identities = 13/35 (37%), Positives = 16/35 (45%)
Query: 394 LSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFP 428
L GD++ L EA W G + T GWFP
Sbjct: 617 LRLNPGDIVELTKAEAEQNWWEGRNTSTNEIGWFP 651
>gi|11034811 catenin (cadherin-associated protein), delta 2 (neural
plakophilin-related arm-repeat protein) [Homo sapiens]
Length = 1225
Score = 37.0 bits (84), Expect = 0.045
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 8/67 (11%)
Query: 277 LPVPPELAPFVGRMSAQESTPIMNGVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDS 336
LP PP + T + G + P+G Y A P+ SP QS S+L+ S
Sbjct: 259 LPAPPRGGSPLAAPQGGSPTKLQRGGSAPEGATY--------AAPRGSSPKQSPSRLAKS 310
Query: 337 YSNTLPV 343
YS + P+
Sbjct: 311 YSTSSPI 317
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,799,727
Number of Sequences: 37866
Number of extensions: 907509
Number of successful extensions: 4086
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 274
Number of HSP's that attempted gapping in prelim test: 3856
Number of HSP's gapped (non-prelim): 504
length of query: 534
length of database: 18,247,518
effective HSP length: 107
effective length of query: 427
effective length of database: 14,195,856
effective search space: 6061630512
effective search space used: 6061630512
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.