Search of human proteins with 221316659

Search of human proteins with 221316659

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|221316659 leupaxin isoform 1 [Homo sapiens]
         (391 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|221316659 leupaxin isoform 1 [Homo sapiens]                        836   0.0  
gi|4758670 leupaxin isoform 2 [Homo sapiens]                          822   0.0  
gi|170932518 paxillin isoform 3 [Homo sapiens]                        444   e-125
gi|170932516 paxillin isoform 2 [Homo sapiens]                        444   e-125
gi|170932514 paxillin isoform 1 [Homo sapiens]                        436   e-122
gi|109638745 transforming growth factor beta 1 induced transcrip...   374   e-104
gi|21361591 transforming growth factor beta 1 induced transcript...   374   e-104
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]            159   5e-39
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]             159   5e-39
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]            155   6e-38
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]            155   6e-38
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ...   140   2e-33
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo...   136   3e-32
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo...   136   3e-32
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo...   136   3e-32
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor...   136   3e-32
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]             135   8e-32
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]             135   8e-32
gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]      124   2e-28
gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]      124   2e-28
gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens]      124   2e-28
gi|30410801 activator of cAMP-responsive element modulator (CREM...   121   9e-28
gi|54112385 four and a half LIM domains 3 [Homo sapiens]              120   3e-27
gi|7662330 actin binding LIM protein family, member 3 [Homo sapi...   118   1e-26
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]   117   1e-26
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]   117   1e-26
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]   117   1e-26
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]   117   1e-26
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]    117   1e-26
gi|194272207 actin binding LIM protein family, member 2 isoform ...   115   9e-26

>gi|221316659 leupaxin isoform 1 [Homo sapiens]
          Length = 391

 Score =  836 bits (2160), Expect = 0.0
 Identities = 391/391 (100%), Positives = 391/391 (100%)

Query: 1   MSTLLISSSDALLEELERSTLQDSDEYSNPAPLPLDQHSRKETNLDETSEILSIQDNTSP 60
           MSTLLISSSDALLEELERSTLQDSDEYSNPAPLPLDQHSRKETNLDETSEILSIQDNTSP
Sbjct: 1   MSTLLISSSDALLEELERSTLQDSDEYSNPAPLPLDQHSRKETNLDETSEILSIQDNTSP 60

Query: 61  LPAQLVYTTNIQELNVYSEAQEPKESPPPSKTSAAAQLDELMAHLTEMQAKVAVRADAGK 120
           LPAQLVYTTNIQELNVYSEAQEPKESPPPSKTSAAAQLDELMAHLTEMQAKVAVRADAGK
Sbjct: 61  LPAQLVYTTNIQELNVYSEAQEPKESPPPSKTSAAAQLDELMAHLTEMQAKVAVRADAGK 120

Query: 121 KHLPDKQDHKASLDSMLGGLEQELQDLGIATVPKGHCASCQKPIAGKVIHALGQSWHPEH 180
           KHLPDKQDHKASLDSMLGGLEQELQDLGIATVPKGHCASCQKPIAGKVIHALGQSWHPEH
Sbjct: 121 KHLPDKQDHKASLDSMLGGLEQELQDLGIATVPKGHCASCQKPIAGKVIHALGQSWHPEH 180

Query: 181 FVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLTAMNQTWHPEHF 240
           FVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLTAMNQTWHPEHF
Sbjct: 181 FVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLTAMNQTWHPEHF 240

Query: 241 FCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSAMDTVWHPECFV 300
           FCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSAMDTVWHPECFV
Sbjct: 241 FCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSAMDTVWHPECFV 300

Query: 301 CGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVC 360
           CGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVC
Sbjct: 301 CGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVC 360

Query: 361 AFCLTQLSKGIFREQNDKTYCQPCFNKLFPL 391
           AFCLTQLSKGIFREQNDKTYCQPCFNKLFPL
Sbjct: 361 AFCLTQLSKGIFREQNDKTYCQPCFNKLFPL 391


>gi|4758670 leupaxin isoform 2 [Homo sapiens]
          Length = 386

 Score =  822 bits (2122), Expect = 0.0
 Identities = 382/382 (100%), Positives = 382/382 (100%)

Query: 10  DALLEELERSTLQDSDEYSNPAPLPLDQHSRKETNLDETSEILSIQDNTSPLPAQLVYTT 69
           DALLEELERSTLQDSDEYSNPAPLPLDQHSRKETNLDETSEILSIQDNTSPLPAQLVYTT
Sbjct: 5   DALLEELERSTLQDSDEYSNPAPLPLDQHSRKETNLDETSEILSIQDNTSPLPAQLVYTT 64

Query: 70  NIQELNVYSEAQEPKESPPPSKTSAAAQLDELMAHLTEMQAKVAVRADAGKKHLPDKQDH 129
           NIQELNVYSEAQEPKESPPPSKTSAAAQLDELMAHLTEMQAKVAVRADAGKKHLPDKQDH
Sbjct: 65  NIQELNVYSEAQEPKESPPPSKTSAAAQLDELMAHLTEMQAKVAVRADAGKKHLPDKQDH 124

Query: 130 KASLDSMLGGLEQELQDLGIATVPKGHCASCQKPIAGKVIHALGQSWHPEHFVCTHCKEE 189
           KASLDSMLGGLEQELQDLGIATVPKGHCASCQKPIAGKVIHALGQSWHPEHFVCTHCKEE
Sbjct: 125 KASLDSMLGGLEQELQDLGIATVPKGHCASCQKPIAGKVIHALGQSWHPEHFVCTHCKEE 184

Query: 190 IGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVF 249
           IGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVF
Sbjct: 185 IGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVF 244

Query: 250 GAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFS 309
           GAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFS
Sbjct: 245 GAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFS 304

Query: 310 TGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSK 369
           TGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSK
Sbjct: 305 TGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSK 364

Query: 370 GIFREQNDKTYCQPCFNKLFPL 391
           GIFREQNDKTYCQPCFNKLFPL
Sbjct: 365 GIFREQNDKTYCQPCFNKLFPL 386


>gi|170932518 paxillin isoform 3 [Homo sapiens]
          Length = 424

 Score =  444 bits (1141), Expect = e-125
 Identities = 203/335 (60%), Positives = 245/335 (73%), Gaps = 12/335 (3%)

Query: 59  SPLPAQLVYTTNIQELNVYSEAQEPKESPPPSKTSAAAQLDELMAHLTEM----QAKVAV 114
           SP+PA    T N  E++        ++    S +SA  +LDELMA L++     Q K   
Sbjct: 97  SPVPA---ITVNQGEMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKFMAQGKTGS 153

Query: 115 RADAGKKHLPDKQDHKASLDSMLGGLEQELQDLGIATVPKGHCASCQKPIAGKVIHALGQ 174
            +  G    P  Q     LDSMLG L+ +L  LG+ATV KG C +C+KPIAG+V+ A+G+
Sbjct: 154 SSPPGGPPKPGSQ-----LDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGK 208

Query: 175 SWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLTAMNQT 234
           +WHPEHFVCTHC+EEIGS  FFER G  YC  DYH LFSPRC YC  PILDKV+TA+++T
Sbjct: 209 TWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRT 268

Query: 235 WHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSAMDTVW 294
           WHPEHFFC+ CG  FG EGFHEKD K YCRKD+  MF+PKCGGC R +LENY+SA++T+W
Sbjct: 269 WHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLW 328

Query: 295 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 354
           HPECFVC +CFT F  GSFFE DG+P+CE+HYH RRG+LC GC +PITGRCI+AM  KFH
Sbjct: 329 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 388

Query: 355 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
           PEHFVCAFCL QL+KG F+EQNDK YCQ CF KLF
Sbjct: 389 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423


>gi|170932516 paxillin isoform 2 [Homo sapiens]
          Length = 557

 Score =  444 bits (1141), Expect = e-125
 Identities = 203/335 (60%), Positives = 245/335 (73%), Gaps = 12/335 (3%)

Query: 59  SPLPAQLVYTTNIQELNVYSEAQEPKESPPPSKTSAAAQLDELMAHLTEM----QAKVAV 114
           SP+PA    T N  E++        ++    S +SA  +LDELMA L++     Q K   
Sbjct: 230 SPVPA---ITVNQGEMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKFMAQGKTGS 286

Query: 115 RADAGKKHLPDKQDHKASLDSMLGGLEQELQDLGIATVPKGHCASCQKPIAGKVIHALGQ 174
            +  G    P  Q     LDSMLG L+ +L  LG+ATV KG C +C+KPIAG+V+ A+G+
Sbjct: 287 SSPPGGPPKPGSQ-----LDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGK 341

Query: 175 SWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLTAMNQT 234
           +WHPEHFVCTHC+EEIGS  FFER G  YC  DYH LFSPRC YC  PILDKV+TA+++T
Sbjct: 342 TWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRT 401

Query: 235 WHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSAMDTVW 294
           WHPEHFFC+ CG  FG EGFHEKD K YCRKD+  MF+PKCGGC R +LENY+SA++T+W
Sbjct: 402 WHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLW 461

Query: 295 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 354
           HPECFVC +CFT F  GSFFE DG+P+CE+HYH RRG+LC GC +PITGRCI+AM  KFH
Sbjct: 462 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 521

Query: 355 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
           PEHFVCAFCL QL+KG F+EQNDK YCQ CF KLF
Sbjct: 522 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556


>gi|170932514 paxillin isoform 1 [Homo sapiens]
          Length = 591

 Score =  436 bits (1121), Expect = e-122
 Identities = 205/364 (56%), Positives = 251/364 (68%), Gaps = 36/364 (9%)

Query: 59  SPLPAQLVYTTNIQELNVYSEAQEPKESPPPSKTSAAAQLDELMAHLTEMQAK-VAVRAD 117
           SP+PA    T N  E++        ++    S +SA  +LDELMA L++ + + +  RAD
Sbjct: 230 SPVPA---ITVNQGEMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKIQGLEQRAD 286

Query: 118 A-----------GKKHLPDKQDHK---------------------ASLDSMLGGLEQELQ 145
                       G +  P  QD                       + LDSMLG L+ +L 
Sbjct: 287 GERCWAAGWPRDGGRSSPGGQDEGGFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLN 346

Query: 146 DLGIATVPKGHCASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCP 205
            LG+ATV KG C +C+KPIAG+V+ A+G++WHPEHFVCTHC+EEIGS  FFER G  YC 
Sbjct: 347 KLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCE 406

Query: 206 NDYHQLFSPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRK 265
            DYH LFSPRC YC  PILDKV+TA+++TWHPEHFFC+ CG  FG EGFHEKD K YCRK
Sbjct: 407 KDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRK 466

Query: 266 DFLAMFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELH 325
           D+  MF+PKCGGC R +LENY+SA++T+WHPECFVC +CFT F  GSFFE DG+P+CE+H
Sbjct: 467 DYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVH 526

Query: 326 YHHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCF 385
           YH RRG+LC GC +PITGRCI+AM  KFHPEHFVCAFCL QL+KG F+EQNDK YCQ CF
Sbjct: 527 YHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCF 586

Query: 386 NKLF 389
            KLF
Sbjct: 587 LKLF 590


>gi|109638745 transforming growth factor beta 1 induced transcript 1
           isoform 1 [Homo sapiens]
          Length = 461

 Score =  374 bits (960), Expect = e-104
 Identities = 178/392 (45%), Positives = 234/392 (59%), Gaps = 37/392 (9%)

Query: 10  DALLEELERSTLQDSDEYSNPAPLPLDQHSRKETNLDETSEILSIQDNTSPLPAQLVYTT 69
           D LL+EL  +    +DE  +  P        ++ +  E  +  S+  + SP         
Sbjct: 94  DRLLQELNATQFNITDEIMSQFPSSKVASGEQKEDQSEDKKRPSLPSSPSP--------- 144

Query: 70  NIQELNVYSEAQEPKESPPPSKTSAAAQLDELMAHLTEM------------QAKVAVRAD 117
                            P  S TSA  +LD LMA L++             Q  V    +
Sbjct: 145 ---------------GLPKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTN 189

Query: 118 AGKKHLPDKQDHKASLDSMLGGLEQELQDLGIATVPKGHCASCQKPIAGKVIHALGQSWH 177
            G    P+    K SLD+MLG L+ +L   G+ T  KG C SC KPIAG+V+ ALG++WH
Sbjct: 190 EGSPSPPEPTG-KGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGRAWH 248

Query: 178 PEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLTAMNQTWHP 237
           PEHFVC  C   +G S FFE+ G  +CP  Y + FSPRC +C  PI  K++TA+   WHP
Sbjct: 249 PEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHP 308

Query: 238 EHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSAMDTVWHPE 297
           EHF C  CGE FG EGFHE++ +PYCR+DFL +F+P+C GC  P+L+NY+SA+  +WHP+
Sbjct: 309 EHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPD 368

Query: 298 CFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFHPEH 357
           CFVC +CF  FS GSFFE +GRP CE H+H RRG+LC  CG P+TGRC+SA+G +FHP+H
Sbjct: 369 CFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDH 428

Query: 358 FVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
           F C FCL  L+KG F+E+  K YCQPCF KLF
Sbjct: 429 FTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 460


>gi|21361591 transforming growth factor beta 1 induced transcript 1
           isoform 2 [Homo sapiens]
          Length = 444

 Score =  374 bits (960), Expect = e-104
 Identities = 178/392 (45%), Positives = 234/392 (59%), Gaps = 37/392 (9%)

Query: 10  DALLEELERSTLQDSDEYSNPAPLPLDQHSRKETNLDETSEILSIQDNTSPLPAQLVYTT 69
           D LL+EL  +    +DE  +  P        ++ +  E  +  S+  + SP         
Sbjct: 77  DRLLQELNATQFNITDEIMSQFPSSKVASGEQKEDQSEDKKRPSLPSSPSP--------- 127

Query: 70  NIQELNVYSEAQEPKESPPPSKTSAAAQLDELMAHLTEM------------QAKVAVRAD 117
                            P  S TSA  +LD LMA L++             Q  V    +
Sbjct: 128 ---------------GLPKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTN 172

Query: 118 AGKKHLPDKQDHKASLDSMLGGLEQELQDLGIATVPKGHCASCQKPIAGKVIHALGQSWH 177
            G    P+    K SLD+MLG L+ +L   G+ T  KG C SC KPIAG+V+ ALG++WH
Sbjct: 173 EGSPSPPEPTG-KGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGRAWH 231

Query: 178 PEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLTAMNQTWHP 237
           PEHFVC  C   +G S FFE+ G  +CP  Y + FSPRC +C  PI  K++TA+   WHP
Sbjct: 232 PEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHP 291

Query: 238 EHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSAMDTVWHPE 297
           EHF C  CGE FG EGFHE++ +PYCR+DFL +F+P+C GC  P+L+NY+SA+  +WHP+
Sbjct: 292 EHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPD 351

Query: 298 CFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFHPEH 357
           CFVC +CF  FS GSFFE +GRP CE H+H RRG+LC  CG P+TGRC+SA+G +FHP+H
Sbjct: 352 CFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFHPDH 411

Query: 358 FVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
           F C FCL  L+KG F+E+  K YCQPCF KLF
Sbjct: 412 FTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 443


>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
          Length = 617

 Score =  159 bits (401), Expect = 5e-39
 Identities = 67/173 (38%), Positives = 93/173 (53%), Gaps = 2/173 (1%)

Query: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRC 216
           C  C   I G  + A+G+SWHPE F C +CK  +    F E     YC   Y Q F+P C
Sbjct: 441 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLC 500

Query: 217 AYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCG 276
           A C   I+ +V+ A+ QTWH   F C+ C + FG   FH +D +PYC KD++ +FS KC 
Sbjct: 501 AKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCH 560

Query: 277 GCNRPVL--ENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYH 327
           GC+ PV   + ++ A+   WH  CF+C  C  +     F+    RP C+ H H
Sbjct: 561 GCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAH 613



 Score =  125 bits (314), Expect = 7e-29
 Identities = 57/172 (33%), Positives = 82/172 (47%), Gaps = 2/172 (1%)

Query: 213 SPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272
           +P C +C   I    L AM ++WHPE F C++C        F E+    YC + +   F+
Sbjct: 438 TPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFA 497

Query: 273 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 332
           P C  CN  ++   + A+   WH  CFVC  C   F    F   DG P+CE  Y +   T
Sbjct: 498 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFST 557

Query: 333 LCHGCGQPITG--RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQ 382
            CHGC  P+    + I A+G+ +H   F+CA C   L    F  + D+  C+
Sbjct: 558 KCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 609



 Score = 79.3 bits (194), Expect = 5e-15
 Identities = 39/118 (33%), Positives = 53/118 (44%)

Query: 272 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 331
           +P CG CN  +   +L AM   WHPE F C  C TS +   F E     +CE  Y     
Sbjct: 438 TPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFA 497

Query: 332 TLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
            LC  C   I G  + A+   +H   FVCA C       +F  ++ + YC+  +  LF
Sbjct: 498 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLF 555



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 24/60 (40%), Positives = 33/60 (55%)

Query: 330 RGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
           R  LC  C   I G  + AMG  +HPE F CA+C T L+   F E+ +  YC+ C+ + F
Sbjct: 437 RTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFF 496



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 17/57 (29%), Positives = 24/57 (42%), Gaps = 2/57 (3%)

Query: 157 CASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQL 211
           C  C  P+    K I ALG +WH   F+C  C   +   PF+ +     C    H +
Sbjct: 559 CHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAHTI 615


>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
          Length = 727

 Score =  159 bits (401), Expect = 5e-39
 Identities = 67/173 (38%), Positives = 93/173 (53%), Gaps = 2/173 (1%)

Query: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRC 216
           C  C   I G  + A+G+SWHPE F C +CK  +    F E     YC   Y Q F+P C
Sbjct: 551 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLC 610

Query: 217 AYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCG 276
           A C   I+ +V+ A+ QTWH   F C+ C + FG   FH +D +PYC KD++ +FS KC 
Sbjct: 611 AKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCH 670

Query: 277 GCNRPVL--ENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYH 327
           GC+ PV   + ++ A+   WH  CF+C  C  +     F+    RP C+ H H
Sbjct: 671 GCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAH 723



 Score =  125 bits (314), Expect = 7e-29
 Identities = 57/172 (33%), Positives = 82/172 (47%), Gaps = 2/172 (1%)

Query: 213 SPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272
           +P C +C   I    L AM ++WHPE F C++C        F E+    YC + +   F+
Sbjct: 548 TPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFA 607

Query: 273 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 332
           P C  CN  ++   + A+   WH  CFVC  C   F    F   DG P+CE  Y +   T
Sbjct: 608 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFST 667

Query: 333 LCHGCGQPITG--RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQ 382
            CHGC  P+    + I A+G+ +H   F+CA C   L    F  + D+  C+
Sbjct: 668 KCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 719



 Score = 79.3 bits (194), Expect = 5e-15
 Identities = 39/118 (33%), Positives = 53/118 (44%)

Query: 272 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 331
           +P CG CN  +   +L AM   WHPE F C  C TS +   F E     +CE  Y     
Sbjct: 548 TPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFA 607

Query: 332 TLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
            LC  C   I G  + A+   +H   FVCA C       +F  ++ + YC+  +  LF
Sbjct: 608 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLF 665



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 24/60 (40%), Positives = 33/60 (55%)

Query: 330 RGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
           R  LC  C   I G  + AMG  +HPE F CA+C T L+   F E+ +  YC+ C+ + F
Sbjct: 547 RTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFF 606



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 17/57 (29%), Positives = 24/57 (42%), Gaps = 2/57 (3%)

Query: 157 CASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQL 211
           C  C  P+    K I ALG +WH   F+C  C   +   PF+ +     C    H +
Sbjct: 669 CHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAHTI 725


>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
          Length = 487

 Score =  155 bits (392), Expect = 6e-38
 Identities = 77/206 (37%), Positives = 103/206 (50%), Gaps = 9/206 (4%)

Query: 131 ASLDSMLGGLEQELQDLGIAT---VPKGH----CASCQKPIAGKVIHALGQSWHPEHFVC 183
           A  +S LG  +   QD  +     +P G     CA C + I G  + ALG+SWHPE F C
Sbjct: 278 APANSALGQTQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNC 337

Query: 184 THCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLTAMNQTWHPEHFFCS 243
            HCK  +    F E  G  YC   Y + F+P C  C   IL +V++A+ QTWH   F C 
Sbjct: 338 AHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCV 397

Query: 244 HCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVWHPECFVC 301
            CG+      FH +D +PYC  D+ A+F   C GC  P+   + +L A+   WH  CFVC
Sbjct: 398 ACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVC 457

Query: 302 GDCFTSFSTGSFFELDGRPFCELHYH 327
             C  S    +FF    +P C+ H H
Sbjct: 458 SVCCESLEGQTFFSKKDKPLCKKHAH 483



 Score =  137 bits (346), Expect = 1e-32
 Identities = 64/172 (37%), Positives = 86/172 (50%), Gaps = 2/172 (1%)

Query: 213 SPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272
           +P CA+C   I    L A+ ++WHPE F C+HC       GF E+    YC   +   F+
Sbjct: 308 TPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFA 367

Query: 273 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 332
           P+CG C R +L   +SA+   WH  CFVC  C        F   DG P+CE  Y+   GT
Sbjct: 368 PECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 427

Query: 333 LCHGCGQPITG--RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQ 382
           +CHGC  PI      + A+GY +H   FVC+ C   L    F  + DK  C+
Sbjct: 428 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 37/118 (31%), Positives = 55/118 (46%)

Query: 272 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 331
           +P C  CN+ +   +L A+   WHPE F C  C  + +   F E  G  +CEL Y     
Sbjct: 308 TPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFA 367

Query: 332 TLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
             C  C + I G  ISA+   +H   FVC  C   +   +F  ++ + YC+  +  LF
Sbjct: 368 PECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALF 425



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 22/61 (36%), Positives = 32/61 (52%)

Query: 329 RRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKL 388
           +R  +C  C Q I G  + A+G  +HPE F CA C   ++   F E+    YC+ C+ K 
Sbjct: 306 KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKF 365

Query: 389 F 389
           F
Sbjct: 366 F 366



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 2/57 (3%)

Query: 157 CASCQKPI-AGKV-IHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQL 211
           C  C+ PI AG + + ALG +WH   FVC+ C E +    FF +     C    H +
Sbjct: 429 CHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSV 485


>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
          Length = 596

 Score =  155 bits (392), Expect = 6e-38
 Identities = 77/206 (37%), Positives = 103/206 (50%), Gaps = 9/206 (4%)

Query: 131 ASLDSMLGGLEQELQDLGIAT---VPKGH----CASCQKPIAGKVIHALGQSWHPEHFVC 183
           A  +S LG  +   QD  +     +P G     CA C + I G  + ALG+SWHPE F C
Sbjct: 387 APANSALGQTQPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNC 446

Query: 184 THCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILDKVLTAMNQTWHPEHFFCS 243
            HCK  +    F E  G  YC   Y + F+P C  C   IL +V++A+ QTWH   F C 
Sbjct: 447 AHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCV 506

Query: 244 HCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVWHPECFVC 301
            CG+      FH +D +PYC  D+ A+F   C GC  P+   + +L A+   WH  CFVC
Sbjct: 507 ACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVC 566

Query: 302 GDCFTSFSTGSFFELDGRPFCELHYH 327
             C  S    +FF    +P C+ H H
Sbjct: 567 SVCCESLEGQTFFSKKDKPLCKKHAH 592



 Score =  137 bits (346), Expect = 1e-32
 Identities = 64/172 (37%), Positives = 86/172 (50%), Gaps = 2/172 (1%)

Query: 213 SPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272
           +P CA+C   I    L A+ ++WHPE F C+HC       GF E+    YC   +   F+
Sbjct: 417 TPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFA 476

Query: 273 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 332
           P+CG C R +L   +SA+   WH  CFVC  C        F   DG P+CE  Y+   GT
Sbjct: 477 PECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGT 536

Query: 333 LCHGCGQPITG--RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQ 382
           +CHGC  PI      + A+GY +H   FVC+ C   L    F  + DK  C+
Sbjct: 537 ICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 588



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 37/118 (31%), Positives = 55/118 (46%)

Query: 272 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 331
           +P C  CN+ +   +L A+   WHPE F C  C  + +   F E  G  +CEL Y     
Sbjct: 417 TPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFA 476

Query: 332 TLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
             C  C + I G  ISA+   +H   FVC  C   +   +F  ++ + YC+  +  LF
Sbjct: 477 PECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALF 534



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 22/61 (36%), Positives = 32/61 (52%)

Query: 329 RRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKL 388
           +R  +C  C Q I G  + A+G  +HPE F CA C   ++   F E+    YC+ C+ K 
Sbjct: 415 KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKF 474

Query: 389 F 389
           F
Sbjct: 475 F 475



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 2/57 (3%)

Query: 157 CASCQKPI-AGKV-IHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQL 211
           C  C+ PI AG + + ALG +WH   FVC+ C E +    FF +     C    H +
Sbjct: 538 CHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKHAHSV 594


>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
           sapiens]
          Length = 325

 Score =  140 bits (353), Expect = 2e-33
 Identities = 82/241 (34%), Positives = 118/241 (48%), Gaps = 8/241 (3%)

Query: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQ-----L 211
           C  C + I G+VI A+  SWHPE F C  C+E +    F + +G   C   +++     L
Sbjct: 71  CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGL 130

Query: 212 FSPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMF 271
               C  C A I ++ L   N  +HP+HF C++CG+   A+   E   + YC      M 
Sbjct: 131 GKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADA-RELKGELYCLPCHDKMG 189

Query: 272 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 331
            P CG C RP+    ++AM   WH E FVC  C   F     +E  G  +CE HY+   G
Sbjct: 190 VPICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFG 249

Query: 332 TLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLS-KGIFREQNDKTYCQPCFNKLFP 390
            +C  C + I G  +SA+   +    F C+ C T+L+ K  F E + K  C+ C+ K FP
Sbjct: 250 DVCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK-FP 308

Query: 391 L 391
           L
Sbjct: 309 L 309



 Score =  139 bits (350), Expect = 4e-33
 Identities = 77/231 (33%), Positives = 116/231 (50%), Gaps = 8/231 (3%)

Query: 165 AGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPIL 224
           A K++++ G+ +H + FVC  C ++     F+E  G  YC +D+  LF+P C  C   I+
Sbjct: 20  AEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFII 79

Query: 225 DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYC-----RKDFLAMFSPKCGGCN 279
            +V+ AMN +WHPE F C  C EV    GF +   +  C     R+    +    C  C+
Sbjct: 80  GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCH 139

Query: 280 RPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT-LCHGCG 338
             + E  L   +  +HP+ F C +C     T    EL G  +C L  H + G  +C  C 
Sbjct: 140 AIIDEQPLIFKNDPYHPDHFNCANCGKEL-TADARELKGELYC-LPCHDKMGVPICGACR 197

Query: 339 QPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
           +PI GR ++AMG ++H EHFVCA C          E+    YC+  +N+LF
Sbjct: 198 RPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLF 248



 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 41/114 (35%), Positives = 59/114 (51%), Gaps = 1/114 (0%)

Query: 274 KCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTL 333
           +C G   P  E  +++   ++H +CFVC  CF  F  G F+E +GR +CE  +       
Sbjct: 12  RCKGGFAPA-EKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPC 70

Query: 334 CHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNK 387
           CH CG+ I GR I AM   +HPE F C  C   L+   F +   +  C+PC N+
Sbjct: 71  CHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNR 124


>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
           1 [Homo sapiens]
          Length = 363

 Score =  136 bits (343), Expect = 3e-32
 Identities = 79/241 (32%), Positives = 116/241 (48%), Gaps = 8/241 (3%)

Query: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQ-----L 211
           C SC + I G+VI A+  +WHP  F C  C  E+    F + +G   C   +++     L
Sbjct: 98  CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 157

Query: 212 FSPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMF 271
               C  C   I ++ L   +  +HP+HF C+HCG+   AE   E   + YC      M 
Sbjct: 158 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKMG 216

Query: 272 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 331
            P CG C RP+    ++A+   WH E FVC  C   F     +E  G  +CE HY+   G
Sbjct: 217 VPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFG 276

Query: 332 TLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLS-KGIFREQNDKTYCQPCFNKLFP 390
            +C+ C   I G  +SA+   +    F C+ C ++L+ K  F E + K  C+ C+ K FP
Sbjct: 277 DVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK-FP 335

Query: 391 L 391
           L
Sbjct: 336 L 336



 Score =  128 bits (321), Expect = 1e-29
 Identities = 75/241 (31%), Positives = 110/241 (45%), Gaps = 10/241 (4%)

Query: 157 CASCQKPI--AGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 214
           C  CQ     A +++++ G+ +H   FVC  C        F+E  G  YC +D+  LF+P
Sbjct: 37  CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 96

Query: 215 RCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYC-----RKDFLA 269
            C  C   I+ +V+ AMN  WHP  F C  C       GF +   +  C     R+    
Sbjct: 97  CCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKG 156

Query: 270 MFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHR 329
           +    C  C+  + E  L      +HP+ F C  C     T    EL G  +C L  H +
Sbjct: 157 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKEL-TAEARELKGELYC-LPCHDK 214

Query: 330 RGT-LCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKL 388
            G  +C  C +PI GR ++A+G ++H EHFVCA C          E+    YC+  +N+L
Sbjct: 215 MGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQL 274

Query: 389 F 389
           F
Sbjct: 275 F 275


>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
           5 [Homo sapiens]
          Length = 336

 Score =  136 bits (343), Expect = 3e-32
 Identities = 79/241 (32%), Positives = 116/241 (48%), Gaps = 8/241 (3%)

Query: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQ-----L 211
           C SC + I G+VI A+  +WHP  F C  C  E+    F + +G   C   +++     L
Sbjct: 71  CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 130

Query: 212 FSPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMF 271
               C  C   I ++ L   +  +HP+HF C+HCG+   AE   E   + YC      M 
Sbjct: 131 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKMG 189

Query: 272 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 331
            P CG C RP+    ++A+   WH E FVC  C   F     +E  G  +CE HY+   G
Sbjct: 190 VPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFG 249

Query: 332 TLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLS-KGIFREQNDKTYCQPCFNKLFP 390
            +C+ C   I G  +SA+   +    F C+ C ++L+ K  F E + K  C+ C+ K FP
Sbjct: 250 DVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK-FP 308

Query: 391 L 391
           L
Sbjct: 309 L 309



 Score =  128 bits (321), Expect = 1e-29
 Identities = 75/241 (31%), Positives = 110/241 (45%), Gaps = 10/241 (4%)

Query: 157 CASCQKPI--AGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 214
           C  CQ     A +++++ G+ +H   FVC  C        F+E  G  YC +D+  LF+P
Sbjct: 10  CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 69

Query: 215 RCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYC-----RKDFLA 269
            C  C   I+ +V+ AMN  WHP  F C  C       GF +   +  C     R+    
Sbjct: 70  CCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKG 129

Query: 270 MFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHR 329
           +    C  C+  + E  L      +HP+ F C  C     T    EL G  +C L  H +
Sbjct: 130 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKEL-TAEARELKGELYC-LPCHDK 187

Query: 330 RGT-LCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKL 388
            G  +C  C +PI GR ++A+G ++H EHFVCA C          E+    YC+  +N+L
Sbjct: 188 MGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQL 247

Query: 389 F 389
           F
Sbjct: 248 F 248


>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
           3 [Homo sapiens]
          Length = 341

 Score =  136 bits (343), Expect = 3e-32
 Identities = 79/241 (32%), Positives = 116/241 (48%), Gaps = 8/241 (3%)

Query: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQ-----L 211
           C SC + I G+VI A+  +WHP  F C  C  E+    F + +G   C   +++     L
Sbjct: 76  CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 135

Query: 212 FSPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMF 271
               C  C   I ++ L   +  +HP+HF C+HCG+   AE   E   + YC      M 
Sbjct: 136 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKMG 194

Query: 272 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 331
            P CG C RP+    ++A+   WH E FVC  C   F     +E  G  +CE HY+   G
Sbjct: 195 VPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFG 254

Query: 332 TLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLS-KGIFREQNDKTYCQPCFNKLFP 390
            +C+ C   I G  +SA+   +    F C+ C ++L+ K  F E + K  C+ C+ K FP
Sbjct: 255 DVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK-FP 313

Query: 391 L 391
           L
Sbjct: 314 L 314



 Score =  128 bits (321), Expect = 1e-29
 Identities = 75/241 (31%), Positives = 110/241 (45%), Gaps = 10/241 (4%)

Query: 157 CASCQKPI--AGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 214
           C  CQ     A +++++ G+ +H   FVC  C        F+E  G  YC +D+  LF+P
Sbjct: 15  CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 74

Query: 215 RCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYC-----RKDFLA 269
            C  C   I+ +V+ AMN  WHP  F C  C       GF +   +  C     R+    
Sbjct: 75  CCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKG 134

Query: 270 MFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHR 329
           +    C  C+  + E  L      +HP+ F C  C     T    EL G  +C L  H +
Sbjct: 135 LGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKEL-TAEARELKGELYC-LPCHDK 192

Query: 330 RGT-LCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKL 388
            G  +C  C +PI GR ++A+G ++H EHFVCA C          E+    YC+  +N+L
Sbjct: 193 MGVPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQL 252

Query: 389 F 389
           F
Sbjct: 253 F 253


>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
           [Homo sapiens]
          Length = 365

 Score =  136 bits (343), Expect = 3e-32
 Identities = 79/241 (32%), Positives = 116/241 (48%), Gaps = 8/241 (3%)

Query: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQ-----L 211
           C SC + I G+VI A+  +WHP  F C  C  E+    F + +G   C   +++     L
Sbjct: 100 CGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGL 159

Query: 212 FSPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMF 271
               C  C   I ++ L   +  +HP+HF C+HCG+   AE   E   + YC      M 
Sbjct: 160 GKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEA-RELKGELYCLPCHDKMG 218

Query: 272 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 331
            P CG C RP+    ++A+   WH E FVC  C   F     +E  G  +CE HY+   G
Sbjct: 219 VPICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFG 278

Query: 332 TLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLS-KGIFREQNDKTYCQPCFNKLFP 390
            +C+ C   I G  +SA+   +    F C+ C ++L+ K  F E + K  C+ C+ K FP
Sbjct: 279 DVCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK-FP 337

Query: 391 L 391
           L
Sbjct: 338 L 338



 Score =  128 bits (322), Expect = 8e-30
 Identities = 84/290 (28%), Positives = 127/290 (43%), Gaps = 21/290 (7%)

Query: 108 MQAKVAVRADAGKKHLPDKQDHKASLDSMLGGLEQELQDLGIATVPKGHCASCQKPI--A 165
           M A++   A +G   L  ++ H+ S     G +   L +          C  CQ     A
Sbjct: 1   MAARLGALAASG---LYRRRQHRQSPPPATGNMSDALAN--------AVCQRCQARFSPA 49

Query: 166 GKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILD 225
            +++++ G+ +H   FVC  C        F+E  G  YC +D+  LF+P C  C   I+ 
Sbjct: 50  ERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIG 109

Query: 226 KVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYC-----RKDFLAMFSPKCGGCNR 280
           +V+ AMN  WHP  F C  C       GF +   +  C     R+    +    C  C+ 
Sbjct: 110 RVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHL 169

Query: 281 PVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT-LCHGCGQ 339
            + E  L      +HP+ F C  C     T    EL G  +C L  H + G  +C  C +
Sbjct: 170 VIDEQPLMFRSDAYHPDHFNCTHCGKEL-TAEARELKGELYC-LPCHDKMGVPICGACRR 227

Query: 340 PITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
           PI GR ++A+G ++H EHFVCA C          E+    YC+  +N+LF
Sbjct: 228 PIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLF 277


>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
          Length = 423

 Score =  135 bits (339), Expect = 8e-32
 Identities = 59/171 (34%), Positives = 88/171 (51%), Gaps = 2/171 (1%)

Query: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRC 216
           C  C K I G+ + ALG ++HPE FVC+ C + +    FFE  G  +CP  Y   ++P C
Sbjct: 248 CHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSC 307

Query: 217 AYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCG 276
           A C   I  +++ A+  TWH   F C+ C        F+ ++  PYC +D+  MF  KC 
Sbjct: 308 AKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCH 367

Query: 277 GCNRPV--LENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELH 325
           GC+  +   + +L A+   WH  CFVC  C  +    +F+    RP C+ H
Sbjct: 368 GCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 418



 Score =  122 bits (306), Expect = 6e-28
 Identities = 56/172 (32%), Positives = 81/172 (47%), Gaps = 2/172 (1%)

Query: 213 SPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272
           +P C  C   I  + L A+   +HPE F CS CG+V    GF E+    +C   +   ++
Sbjct: 245 TPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 304

Query: 273 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 332
           P C  C + +    + A+   WH  CF C  C T     +F+  +G P+CE  Y    GT
Sbjct: 305 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGT 364

Query: 333 LCHGCGQPITG--RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQ 382
            CHGC   I    R + A+G+ +H   FVCA C   L    F  + D+  C+
Sbjct: 365 KCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 416



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 39/118 (33%), Positives = 54/118 (45%)

Query: 272 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 331
           +P C  C++ +   YL A+   +HPE FVC  C      G FFE  G  FC   Y  R  
Sbjct: 245 TPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 304

Query: 332 TLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
             C  C + ITG  + A+   +H   F CA C T +    F  +    YC+  + K+F
Sbjct: 305 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMF 362


>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
          Length = 457

 Score =  135 bits (339), Expect = 8e-32
 Identities = 59/171 (34%), Positives = 88/171 (51%), Gaps = 2/171 (1%)

Query: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRC 216
           C  C K I G+ + ALG ++HPE FVC+ C + +    FFE  G  +CP  Y   ++P C
Sbjct: 282 CHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSC 341

Query: 217 AYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCG 276
           A C   I  +++ A+  TWH   F C+ C        F+ ++  PYC +D+  MF  KC 
Sbjct: 342 AKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCH 401

Query: 277 GCNRPV--LENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELH 325
           GC+  +   + +L A+   WH  CFVC  C  +    +F+    RP C+ H
Sbjct: 402 GCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 452



 Score =  122 bits (306), Expect = 6e-28
 Identities = 56/172 (32%), Positives = 81/172 (47%), Gaps = 2/172 (1%)

Query: 213 SPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272
           +P C  C   I  + L A+   +HPE F CS CG+V    GF E+    +C   +   ++
Sbjct: 279 TPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 338

Query: 273 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 332
           P C  C + +    + A+   WH  CF C  C T     +F+  +G P+CE  Y    GT
Sbjct: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGT 398

Query: 333 LCHGCGQPITG--RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQ 382
            CHGC   I    R + A+G+ +H   FVCA C   L    F  + D+  C+
Sbjct: 399 KCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 450



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 39/118 (33%), Positives = 54/118 (45%)

Query: 272 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 331
           +P C  C++ +   YL A+   +HPE FVC  C      G FFE  G  FC   Y  R  
Sbjct: 279 TPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 338

Query: 332 TLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
             C  C + ITG  + A+   +H   F CA C T +    F  +    YC+  + K+F
Sbjct: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMF 396


>gi|51173715 actin-binding LIM protein 1 isoform c [Homo sapiens]
          Length = 746

 Score =  124 bits (310), Expect = 2e-28
 Identities = 68/228 (29%), Positives = 101/228 (44%), Gaps = 11/228 (4%)

Query: 153 PKGHCASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLF 212
           P  HC  C +P  G+V+    + +H + F C  C  ++    FF ++G   C  DY +++
Sbjct: 35  PVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMY 94

Query: 213 SPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVF---------GAEGFHEKDKKPYC 263
             RC  C   +  +V+TA+ +T+HP  F C+ C   F         G +   +   +P  
Sbjct: 95  GTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMS 154

Query: 264 RKDFLAMFSPKCGGCNRPVLENY-LSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFC 322
                  FS  C GC R +     L A+D  WH  CF C  C     TG +   DG P+C
Sbjct: 155 SSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSC-GKVLTGEYISKDGAPYC 213

Query: 323 ELHYHHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKG 370
           E  Y    G  C  C Q ITG+ + A    +HP    C+ C    ++G
Sbjct: 214 EKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEG 261



 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 54/172 (31%), Positives = 77/172 (44%), Gaps = 11/172 (6%)

Query: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEI---------GSSPFFERSGLAYCPND 207
           C  C + + G+V+ ALG+++HP  F CT CK            G     +        + 
Sbjct: 98  CHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSP 157

Query: 208 YHQLFSPRCAYCAAPILD-KVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKD 266
               FS  CA C   I + + L A+++ WH   F C  CG+V   E +  KD  PYC KD
Sbjct: 158 KETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPYCEKD 216

Query: 267 FLAMFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDG 318
           +  +F  KC  C++ +    L A D  +HP C  C  C   F+ G    L G
Sbjct: 217 YQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQG 268



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 16/56 (28%), Positives = 27/56 (48%)

Query: 334 CHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
           CH CG+P  G  +      FH + F C  C   L++G F  +N +  C   + +++
Sbjct: 39  CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMY 94


>gi|51173713 actin-binding LIM protein 1 isoform b [Homo sapiens]
          Length = 718

 Score =  124 bits (310), Expect = 2e-28
 Identities = 68/228 (29%), Positives = 101/228 (44%), Gaps = 11/228 (4%)

Query: 153 PKGHCASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLF 212
           P  HC  C +P  G+V+    + +H + F C  C  ++    FF ++G   C  DY +++
Sbjct: 35  PVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMY 94

Query: 213 SPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVF---------GAEGFHEKDKKPYC 263
             RC  C   +  +V+TA+ +T+HP  F C+ C   F         G +   +   +P  
Sbjct: 95  GTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMS 154

Query: 264 RKDFLAMFSPKCGGCNRPVLENY-LSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFC 322
                  FS  C GC R +     L A+D  WH  CF C  C     TG +   DG P+C
Sbjct: 155 SSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSC-GKVLTGEYISKDGAPYC 213

Query: 323 ELHYHHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKG 370
           E  Y    G  C  C Q ITG+ + A    +HP    C+ C    ++G
Sbjct: 214 EKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEG 261



 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 54/172 (31%), Positives = 77/172 (44%), Gaps = 11/172 (6%)

Query: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEI---------GSSPFFERSGLAYCPND 207
           C  C + + G+V+ ALG+++HP  F CT CK            G     +        + 
Sbjct: 98  CHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSP 157

Query: 208 YHQLFSPRCAYCAAPILD-KVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKD 266
               FS  CA C   I + + L A+++ WH   F C  CG+V   E +  KD  PYC KD
Sbjct: 158 KETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPYCEKD 216

Query: 267 FLAMFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDG 318
           +  +F  KC  C++ +    L A D  +HP C  C  C   F+ G    L G
Sbjct: 217 YQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQG 268



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 16/56 (28%), Positives = 27/56 (48%)

Query: 334 CHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
           CH CG+P  G  +      FH + F C  C   L++G F  +N +  C   + +++
Sbjct: 39  CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMY 94


>gi|51173711 actin-binding LIM protein 1 isoform a [Homo sapiens]
          Length = 778

 Score =  124 bits (310), Expect = 2e-28
 Identities = 68/228 (29%), Positives = 101/228 (44%), Gaps = 11/228 (4%)

Query: 153 PKGHCASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLF 212
           P  HC  C +P  G+V+    + +H + F C  C  ++    FF ++G   C  DY +++
Sbjct: 95  PVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMY 154

Query: 213 SPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVF---------GAEGFHEKDKKPYC 263
             RC  C   +  +V+TA+ +T+HP  F C+ C   F         G +   +   +P  
Sbjct: 155 GTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMS 214

Query: 264 RKDFLAMFSPKCGGCNRPVLENY-LSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFC 322
                  FS  C GC R +     L A+D  WH  CF C  C     TG +   DG P+C
Sbjct: 215 SSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSC-GKVLTGEYISKDGAPYC 273

Query: 323 ELHYHHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKG 370
           E  Y    G  C  C Q ITG+ + A    +HP    C+ C    ++G
Sbjct: 274 EKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEG 321



 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 54/172 (31%), Positives = 77/172 (44%), Gaps = 11/172 (6%)

Query: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEI---------GSSPFFERSGLAYCPND 207
           C  C + + G+V+ ALG+++HP  F CT CK            G     +        + 
Sbjct: 158 CHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSP 217

Query: 208 YHQLFSPRCAYCAAPILD-KVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKD 266
               FS  CA C   I + + L A+++ WH   F C  CG+V   E +  KD  PYC KD
Sbjct: 218 KETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGE-YISKDGAPYCEKD 276

Query: 267 FLAMFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDG 318
           +  +F  KC  C++ +    L A D  +HP C  C  C   F+ G    L G
Sbjct: 277 YQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQG 328



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 16/56 (28%), Positives = 27/56 (48%)

Query: 334 CHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
           CH CG+P  G  +      FH + F C  C   L++G F  +N +  C   + +++
Sbjct: 99  CHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMY 154


>gi|30410801 activator of cAMP-responsive element modulator (CREM)
           in testis [Homo sapiens]
          Length = 284

 Score =  121 bits (304), Expect = 9e-28
 Identities = 66/237 (27%), Positives = 96/237 (40%), Gaps = 8/237 (3%)

Query: 156 HCASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFS 213
           +C  C+KPI    K +    + WH   F CT C   +   PF  +     C   Y    S
Sbjct: 40  YCEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECS 99

Query: 214 PRCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMF 271
            +C +C   I+   + +      WH   F C +C +  G +    K+   YC   F   F
Sbjct: 100 SKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEF 159

Query: 272 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 331
           +  C  C + +    ++  D +WH ECF+C  C        F   D  PFC   Y+H   
Sbjct: 160 AHYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYA 219

Query: 332 TLCHGCGQPITG----RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPC 384
             C  C +PI+G    + I     ++H E F C  C   L    F  QN + +CQ C
Sbjct: 220 NKCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276



 Score = 99.8 bits (247), Expect = 4e-21
 Identities = 55/214 (25%), Positives = 88/214 (41%), Gaps = 4/214 (1%)

Query: 180 HFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPILD--KVLTAMNQTWHP 237
           HF C +C   +    +  +    YC   Y ++FS  C  C  PI    K L   ++ WH 
Sbjct: 5   HFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHE 64

Query: 238 EHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVWH 295
             F C+ C      + F  KD++  C + +    S KC  C R ++     +      WH
Sbjct: 65  GCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWH 124

Query: 296 PECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFHP 355
             CFVC +C     T      +   +C   +       C+ C + IT   I+     +H 
Sbjct: 125 ETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHK 184

Query: 356 EHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
           E F+C+ C   L +  F  ++D  +C  C+N L+
Sbjct: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLY 218


>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
          Length = 280

 Score =  120 bits (300), Expect = 3e-27
 Identities = 62/189 (32%), Positives = 88/189 (46%), Gaps = 18/189 (9%)

Query: 157 CASCQKPI--AGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 214
           C++C + +    + +   GQ+WH   F+C+ C++ +GS  F    G  YC   Y   F+P
Sbjct: 101 CSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAP 160

Query: 215 RCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPK 274
           RCA C+  +    +T  +Q WH E   C+ C      + F  +D+ PYC   F  +F+PK
Sbjct: 161 RCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPK 220

Query: 275 CGGCNRPVL----ENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRR 330
           C  C RP++      Y+S  D  WH  CF C  C TS   G  F  DG            
Sbjct: 221 CSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSL-VGQGFVPDGDQ---------- 269

Query: 331 GTLCHGCGQ 339
             LC GC Q
Sbjct: 270 -VLCQGCSQ 277



 Score =  113 bits (283), Expect = 3e-25
 Identities = 65/236 (27%), Positives = 98/236 (41%), Gaps = 8/236 (3%)

Query: 157 CASCQKPIA--GKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 214
           CA CQ+ I    + +    + +H   F C  C+  +   PF  +     C + Y   FS 
Sbjct: 40  CAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSS 99

Query: 215 RCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272
           +C+ C   ++   + L    QTWH   F CS C +  G+  F       YC   +   F+
Sbjct: 100 QCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFA 159

Query: 273 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 332
           P+C  C++ + +  ++  D  WH EC VC  C T  +   F   D  P+C   +      
Sbjct: 160 PRCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAP 219

Query: 333 LCHGCGQPIT----GRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPC 384
            C  C +PI     G+ +S     +H   F CA C T L    F    D+  CQ C
Sbjct: 220 KCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275



 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 56/215 (26%), Positives = 85/215 (39%), Gaps = 4/215 (1%)

Query: 179 EHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPIL--DKVLTAMNQTWH 236
           E F C  C E +    + +     YC   Y   F+  CA C   I    + L   ++ +H
Sbjct: 3   ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62

Query: 237 PEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVW 294
              F C  C      E F  +D +  C   + + FS +C  C   V+     L      W
Sbjct: 63  EGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTW 122

Query: 295 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 354
           H  CF+C  C     + SF    G  +C   Y ++    C  C + +T   ++     +H
Sbjct: 123 HEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQPWH 182

Query: 355 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
            E  VC  C T L+   F  +++  YC  CF +LF
Sbjct: 183 RECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELF 217


>gi|7662330 actin binding LIM protein family, member 3 [Homo
           sapiens]
          Length = 683

 Score =  118 bits (295), Expect = 1e-26
 Identities = 69/225 (30%), Positives = 100/225 (44%), Gaps = 12/225 (5%)

Query: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRC 216
           C  C     G+V+      +H   F C  C   +  S FF ++    C  DY QL+  RC
Sbjct: 23  CYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDYQQLYGTRC 82

Query: 217 AYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFG-AEGFHEKDKKPYCRKDFLAMFSPK- 274
             C   I  +V++A+ +T+HP+ F CS C + F   +      K+  C+    +M S K 
Sbjct: 83  DSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCSQSMASSKP 142

Query: 275 --------CGGCNRPVLENY-LSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELH 325
                   C GC   +     L A+D  WH  CF C  C +   TG +   DG P+CE  
Sbjct: 143 IKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQTC-SVILTGEYISKDGVPYCESD 201

Query: 326 YHHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKG 370
           YH + G  C  C + I+GR + A G  +HP    C  C    ++G
Sbjct: 202 YHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEG 246



 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 57/182 (31%), Positives = 80/182 (43%), Gaps = 16/182 (8%)

Query: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGL-AYCPNDYHQLFSPR 215
           C SC+  I G+VI ALG+++HP+ FVC+ C++          SG    C      + S +
Sbjct: 82  CDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCSQSMASSK 141

Query: 216 ---------CAYCAAPILD-KVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRK 265
                    CA C   I   + L A+++ WH   F C  C  +   E +  KD  PYC  
Sbjct: 142 PIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQTCSVILTGE-YISKDGVPYCES 200

Query: 266 DFLAMFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDG----RPF 321
           D+ A F  KC  C+R +    L A    +HP C  C  C   F+ G    L G     P 
Sbjct: 201 DYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPI 260

Query: 322 CE 323
           C+
Sbjct: 261 CK 262



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 49/205 (23%), Positives = 85/205 (41%), Gaps = 15/205 (7%)

Query: 199 SGLAYCPNDYHQLFSP---RCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFH 255
           + + Y  N Y+   S    +C  C      +V+   N  +H   F C  CG      GF 
Sbjct: 3   TSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFF 62

Query: 256 EKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFE 315
            K+++  C +D+  ++  +C  C   +    +SA+   +HP+CFVC  C   F  G    
Sbjct: 63  FKNQEYICTQDYQQLYGTRCDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDKVT 122

Query: 316 LDGRP-FCELHYHH---------RRGTLCHGCGQPIT-GRCISAMGYKFHPEHFVCAFCL 364
             G+   C+              R  + C GC + I  G+ + A+  ++H   F C  C 
Sbjct: 123 FSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQTCS 182

Query: 365 TQLSKGIFREQNDKTYCQPCFNKLF 389
             L+ G +  ++   YC+  ++  F
Sbjct: 183 VILT-GEYISKDGVPYCESDYHAQF 206


>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score =  117 bits (294), Expect = 1e-26
 Identities = 66/241 (27%), Positives = 99/241 (41%), Gaps = 9/241 (3%)

Query: 157 CASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 214
           C  C+KPI    K +H   + WH   F C  C   + +  F  +     C     +  SP
Sbjct: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99

Query: 215 RCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272
           +C  C   I+  D+ +      WH + F CS+C +V G   F  K +  YC       F+
Sbjct: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159

Query: 273 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 332
             C  CN+ +    ++  D  WH +CFVC  C    +   F  ++ + +C   Y +    
Sbjct: 160 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219

Query: 333 LCHGCGQPITG-----RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNK 387
            C GC  PITG       ++  G  +H   F C  C   L+   F    ++ YC  C  K
Sbjct: 220 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 279

Query: 388 L 388
           L
Sbjct: 280 L 280



 Score =  107 bits (267), Expect = 2e-23
 Identities = 60/211 (28%), Positives = 91/211 (43%), Gaps = 4/211 (1%)

Query: 179 EHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPI--LDKVLTAMNQTWH 236
           E F C +C++ +    + ++ G   C   + +  +  C  C  PI    K +   N+ WH
Sbjct: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62

Query: 237 PEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVW 294
              F C+ C      E F  KD K  C K      SPKC GC + ++  +  +    TVW
Sbjct: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122

Query: 295 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 354
           H +CF C +C     TGSFF      +C   +  +    C  C + IT   I+     +H
Sbjct: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 182

Query: 355 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCF 385
            + FVC  C  +L+   F    D+ YC  C+
Sbjct: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 32/113 (28%), Positives = 44/113 (38%), Gaps = 5/113 (4%)

Query: 156 HCASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPR 215
           HC  C K I    I    Q WH + FVC  C +++    F       YC + Y    + +
Sbjct: 161 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 220

Query: 216 CAYCAAPIL-----DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYC 263
           CA C  PI        V+    Q+WH   F C  C      + F    ++ YC
Sbjct: 221 CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 36/156 (23%), Positives = 58/156 (37%), Gaps = 4/156 (2%)

Query: 238 EHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSA--MDTVWH 295
           E F C +C +    + + +KD    C K F    +  C  C +P+  +       +  WH
Sbjct: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62

Query: 296 PECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITG--RCISAMGYKF 353
             CF C  C    +  +F   D +  C           C GC + I    + +   G  +
Sbjct: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122

Query: 354 HPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
           H + F C+ C   +  G F  + +  YC  C    F
Sbjct: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 158


>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score =  117 bits (294), Expect = 1e-26
 Identities = 66/241 (27%), Positives = 99/241 (41%), Gaps = 9/241 (3%)

Query: 157 CASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 214
           C  C+KPI    K +H   + WH   F C  C   + +  F  +     C     +  SP
Sbjct: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99

Query: 215 RCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272
           +C  C   I+  D+ +      WH + F CS+C +V G   F  K +  YC       F+
Sbjct: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159

Query: 273 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 332
             C  CN+ +    ++  D  WH +CFVC  C    +   F  ++ + +C   Y +    
Sbjct: 160 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219

Query: 333 LCHGCGQPITG-----RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNK 387
            C GC  PITG       ++  G  +H   F C  C   L+   F    ++ YC  C  K
Sbjct: 220 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 279

Query: 388 L 388
           L
Sbjct: 280 L 280



 Score =  107 bits (267), Expect = 2e-23
 Identities = 60/211 (28%), Positives = 91/211 (43%), Gaps = 4/211 (1%)

Query: 179 EHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPI--LDKVLTAMNQTWH 236
           E F C +C++ +    + ++ G   C   + +  +  C  C  PI    K +   N+ WH
Sbjct: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62

Query: 237 PEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVW 294
              F C+ C      E F  KD K  C K      SPKC GC + ++  +  +    TVW
Sbjct: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122

Query: 295 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 354
           H +CF C +C     TGSFF      +C   +  +    C  C + IT   I+     +H
Sbjct: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 182

Query: 355 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCF 385
            + FVC  C  +L+   F    D+ YC  C+
Sbjct: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 32/113 (28%), Positives = 44/113 (38%), Gaps = 5/113 (4%)

Query: 156 HCASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPR 215
           HC  C K I    I    Q WH + FVC  C +++    F       YC + Y    + +
Sbjct: 161 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 220

Query: 216 CAYCAAPIL-----DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYC 263
           CA C  PI        V+    Q+WH   F C  C      + F    ++ YC
Sbjct: 221 CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 36/156 (23%), Positives = 58/156 (37%), Gaps = 4/156 (2%)

Query: 238 EHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSA--MDTVWH 295
           E F C +C +    + + +KD    C K F    +  C  C +P+  +       +  WH
Sbjct: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62

Query: 296 PECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITG--RCISAMGYKF 353
             CF C  C    +  +F   D +  C           C GC + I    + +   G  +
Sbjct: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122

Query: 354 HPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
           H + F C+ C   +  G F  + +  YC  C    F
Sbjct: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 158


>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
          Length = 309

 Score =  117 bits (294), Expect = 1e-26
 Identities = 66/241 (27%), Positives = 99/241 (41%), Gaps = 9/241 (3%)

Query: 157 CASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 214
           C  C+KPI    K +H   + WH   F C  C   + +  F  +     C     +  SP
Sbjct: 69  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 128

Query: 215 RCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272
           +C  C   I+  D+ +      WH + F CS+C +V G   F  K +  YC       F+
Sbjct: 129 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 188

Query: 273 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 332
             C  CN+ +    ++  D  WH +CFVC  C    +   F  ++ + +C   Y +    
Sbjct: 189 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 248

Query: 333 LCHGCGQPITG-----RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNK 387
            C GC  PITG       ++  G  +H   F C  C   L+   F    ++ YC  C  K
Sbjct: 249 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 308

Query: 388 L 388
           L
Sbjct: 309 L 309



 Score =  107 bits (267), Expect = 2e-23
 Identities = 60/211 (28%), Positives = 91/211 (43%), Gaps = 4/211 (1%)

Query: 179 EHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPI--LDKVLTAMNQTWH 236
           E F C +C++ +    + ++ G   C   + +  +  C  C  PI    K +   N+ WH
Sbjct: 32  EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 91

Query: 237 PEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVW 294
              F C+ C      E F  KD K  C K      SPKC GC + ++  +  +    TVW
Sbjct: 92  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 151

Query: 295 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 354
           H +CF C +C     TGSFF      +C   +  +    C  C + IT   I+     +H
Sbjct: 152 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 211

Query: 355 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCF 385
            + FVC  C  +L+   F    D+ YC  C+
Sbjct: 212 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 242



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 32/113 (28%), Positives = 44/113 (38%), Gaps = 5/113 (4%)

Query: 156 HCASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPR 215
           HC  C K I    I    Q WH + FVC  C +++    F       YC + Y    + +
Sbjct: 190 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 249

Query: 216 CAYCAAPIL-----DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYC 263
           CA C  PI        V+    Q+WH   F C  C      + F    ++ YC
Sbjct: 250 CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 302



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 36/156 (23%), Positives = 58/156 (37%), Gaps = 4/156 (2%)

Query: 238 EHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSA--MDTVWH 295
           E F C +C +    + + +KD    C K F    +  C  C +P+  +       +  WH
Sbjct: 32  EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 91

Query: 296 PECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITG--RCISAMGYKF 353
             CF C  C    +  +F   D +  C           C GC + I    + +   G  +
Sbjct: 92  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 151

Query: 354 HPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
           H + F C+ C   +  G F  + +  YC  C    F
Sbjct: 152 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 187


>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
          Length = 296

 Score =  117 bits (294), Expect = 1e-26
 Identities = 66/241 (27%), Positives = 99/241 (41%), Gaps = 9/241 (3%)

Query: 157 CASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 214
           C  C+KPI    K +H   + WH   F C  C   + +  F  +     C     +  SP
Sbjct: 56  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 115

Query: 215 RCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272
           +C  C   I+  D+ +      WH + F CS+C +V G   F  K +  YC       F+
Sbjct: 116 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 175

Query: 273 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 332
             C  CN+ +    ++  D  WH +CFVC  C    +   F  ++ + +C   Y +    
Sbjct: 176 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 235

Query: 333 LCHGCGQPITG-----RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNK 387
            C GC  PITG       ++  G  +H   F C  C   L+   F    ++ YC  C  K
Sbjct: 236 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 295

Query: 388 L 388
           L
Sbjct: 296 L 296



 Score =  107 bits (267), Expect = 2e-23
 Identities = 60/211 (28%), Positives = 91/211 (43%), Gaps = 4/211 (1%)

Query: 179 EHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPI--LDKVLTAMNQTWH 236
           E F C +C++ +    + ++ G   C   + +  +  C  C  PI    K +   N+ WH
Sbjct: 19  EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 78

Query: 237 PEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVW 294
              F C+ C      E F  KD K  C K      SPKC GC + ++  +  +    TVW
Sbjct: 79  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 138

Query: 295 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 354
           H +CF C +C     TGSFF      +C   +  +    C  C + IT   I+     +H
Sbjct: 139 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 198

Query: 355 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCF 385
            + FVC  C  +L+   F    D+ YC  C+
Sbjct: 199 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 229



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 32/113 (28%), Positives = 44/113 (38%), Gaps = 5/113 (4%)

Query: 156 HCASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPR 215
           HC  C K I    I    Q WH + FVC  C +++    F       YC + Y    + +
Sbjct: 177 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 236

Query: 216 CAYCAAPIL-----DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYC 263
           CA C  PI        V+    Q+WH   F C  C      + F    ++ YC
Sbjct: 237 CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 289



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 36/156 (23%), Positives = 58/156 (37%), Gaps = 4/156 (2%)

Query: 238 EHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSA--MDTVWH 295
           E F C +C +    + + +KD    C K F    +  C  C +P+  +       +  WH
Sbjct: 19  EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 78

Query: 296 PECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITG--RCISAMGYKF 353
             CF C  C    +  +F   D +  C           C GC + I    + +   G  +
Sbjct: 79  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 138

Query: 354 HPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
           H + F C+ C   +  G F  + +  YC  C    F
Sbjct: 139 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 174


>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score =  117 bits (294), Expect = 1e-26
 Identities = 66/241 (27%), Positives = 99/241 (41%), Gaps = 9/241 (3%)

Query: 157 CASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 214
           C  C+KPI    K +H   + WH   F C  C   + +  F  +     C     +  SP
Sbjct: 40  CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99

Query: 215 RCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272
           +C  C   I+  D+ +      WH + F CS+C +V G   F  K +  YC       F+
Sbjct: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159

Query: 273 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 332
             C  CN+ +    ++  D  WH +CFVC  C    +   F  ++ + +C   Y +    
Sbjct: 160 KHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAK 219

Query: 333 LCHGCGQPITG-----RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNK 387
            C GC  PITG       ++  G  +H   F C  C   L+   F    ++ YC  C  K
Sbjct: 220 KCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKK 279

Query: 388 L 388
           L
Sbjct: 280 L 280



 Score =  107 bits (267), Expect = 2e-23
 Identities = 60/211 (28%), Positives = 91/211 (43%), Gaps = 4/211 (1%)

Query: 179 EHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPI--LDKVLTAMNQTWH 236
           E F C +C++ +    + ++ G   C   + +  +  C  C  PI    K +   N+ WH
Sbjct: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62

Query: 237 PEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVW 294
              F C+ C      E F  KD K  C K      SPKC GC + ++  +  +    TVW
Sbjct: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122

Query: 295 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 354
           H +CF C +C     TGSFF      +C   +  +    C  C + IT   I+     +H
Sbjct: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWH 182

Query: 355 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCF 385
            + FVC  C  +L+   F    D+ YC  C+
Sbjct: 183 ADCFVCVTCSKKLAGQRFTAVEDQYYCVDCY 213



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 32/113 (28%), Positives = 44/113 (38%), Gaps = 5/113 (4%)

Query: 156 HCASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPR 215
           HC  C K I    I    Q WH + FVC  C +++    F       YC + Y    + +
Sbjct: 161 HCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKK 220

Query: 216 CAYCAAPIL-----DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYC 263
           CA C  PI        V+    Q+WH   F C  C      + F    ++ YC
Sbjct: 221 CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 36/156 (23%), Positives = 58/156 (37%), Gaps = 4/156 (2%)

Query: 238 EHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENYLSA--MDTVWH 295
           E F C +C +    + + +KD    C K F    +  C  C +P+  +       +  WH
Sbjct: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62

Query: 296 PECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITG--RCISAMGYKF 353
             CF C  C    +  +F   D +  C           C GC + I    + +   G  +
Sbjct: 63  DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122

Query: 354 HPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
           H + F C+ C   +  G F  + +  YC  C    F
Sbjct: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKF 158


>gi|194272207 actin binding LIM protein family, member 2 isoform 7
           [Homo sapiens]
          Length = 470

 Score =  115 bits (287), Expect = 9e-26
 Identities = 68/226 (30%), Positives = 99/226 (43%), Gaps = 13/226 (5%)

Query: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRC 216
           C +C     G+V+    + +H + FVC  C  ++    FF R G   C  DY +L+  RC
Sbjct: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRC 83

Query: 217 AYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVF---------GAEGFHEKDKKPYC--RK 265
             C   I  +V++A+ +T+HP+ F C+ C   F         G E   +K   P      
Sbjct: 84  FSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSS 143

Query: 266 DFLAMFSPKCGGCNRPVLENY-LSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCEL 324
             L+     CGGC   +     L A+D  WH  CF C  C        +   DG P+CE 
Sbjct: 144 AHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSC-GKLLNAEYISKDGLPYCEA 202

Query: 325 HYHHRRGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKG 370
            YH + G  C  C + ITGR + A    +HP   +C  C    ++G
Sbjct: 203 DYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEG 248



 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 52/174 (29%), Positives = 78/174 (44%), Gaps = 13/174 (7%)

Query: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEI---------GSSPFFERSGLAYCPND 207
           C SC + I G+V+ ALG+++HP+ FVC  C+            G     ++  L      
Sbjct: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGS 142

Query: 208 YHQLFSP--RCAYCAAPILD-KVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCR 264
              L      C  C   I + + L A+++ WH   F C  CG++  AE +  KD  PYC 
Sbjct: 143 SAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAE-YISKDGLPYCE 201

Query: 265 KDFLAMFSPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDG 318
            D+ A F  +C  C + +    L A +  +HP C +C  C   F+ G    L G
Sbjct: 202 ADYHAKFGIRCDSCEKYITGRVLEAGEKHYHPSCALCVRCGQMFAEGEEMYLQG 255



 Score = 75.9 bits (185), Expect = 6e-14
 Identities = 40/111 (36%), Positives = 47/111 (42%), Gaps = 1/111 (0%)

Query: 275 CGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLC 334
           C  C        L   D  +H +CFVC  C    + G FF   G   C L Y    GT C
Sbjct: 24  CNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRC 83

Query: 335 HGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDK-TYCQPC 384
             C Q I G  +SA+G  +HP+ FVCA C      G     N K   CQ C
Sbjct: 84  FSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKC 134



 Score = 33.1 bits (74), Expect = 0.44
 Identities = 16/57 (28%), Positives = 26/57 (45%)

Query: 333 LCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
           LC+ CG    G  +      FH + FVC  C   L++G F  +  +  C   + +L+
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLY 79


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,503,138
Number of Sequences: 37866
Number of extensions: 890895
Number of successful extensions: 4239
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 115
Number of HSP's successfully gapped in prelim test: 122
Number of HSP's that attempted gapping in prelim test: 3133
Number of HSP's gapped (non-prelim): 615
length of query: 391
length of database: 18,247,518
effective HSP length: 104
effective length of query: 287
effective length of database: 14,309,454
effective search space: 4106813298
effective search space used: 4106813298
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.