BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|221316642 nuclear distribution gene E homolog 1 [Homo sapiens] (335 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|221316642 nuclear distribution gene E homolog 1 [Homo sapiens] 654 0.0 gi|8923110 nuclear distribution gene E homolog 1 [Homo sapiens] 654 0.0 gi|13540600 nudE nuclear distribution gene E homolog (A. nidulan... 339 2e-93 gi|71284108 nudE nuclear distribution gene E homolog (A. nidulan... 339 2e-93 gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 62 6e-10 gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 60 4e-09 gi|31982906 cingulin-like 1 [Homo sapiens] 59 5e-09 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 59 6e-09 gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 58 1e-08 gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 56 4e-08 gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 56 4e-08 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 56 5e-08 gi|41872583 Rho-associated, coiled-coil containing protein kinas... 55 9e-08 gi|32698688 citron [Homo sapiens] 55 9e-08 gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 54 2e-07 gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 54 2e-07 gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 54 2e-07 gi|156104908 myosin heavy chain 6 [Homo sapiens] 54 2e-07 gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 54 3e-07 gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 53 3e-07 gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 53 3e-07 gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 53 3e-07 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 53 3e-07 gi|102467235 inner centromere protein antigens 135/155kDa isofor... 53 3e-07 gi|102467242 inner centromere protein antigens 135/155kDa isofor... 53 3e-07 gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 53 4e-07 gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 53 4e-07 gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 53 4e-07 gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 53 4e-07 gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 53 4e-07 >gi|221316642 nuclear distribution gene E homolog 1 [Homo sapiens] Length = 335 Score = 654 bits (1687), Expect = 0.0 Identities = 335/335 (100%), Positives = 335/335 (100%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR Sbjct: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA Sbjct: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120 Query: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL Sbjct: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180 Query: 181 AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDST 240 AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDST Sbjct: 181 AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDST 240 Query: 241 GGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDG 300 GGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDG Sbjct: 241 GGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDG 300 Query: 301 GERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC 335 GERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC Sbjct: 301 GERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC 335 >gi|8923110 nuclear distribution gene E homolog 1 [Homo sapiens] Length = 335 Score = 654 bits (1687), Expect = 0.0 Identities = 335/335 (100%), Positives = 335/335 (100%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR Sbjct: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA Sbjct: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120 Query: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL Sbjct: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180 Query: 181 AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDST 240 AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDST Sbjct: 181 AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDST 240 Query: 241 GGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDG 300 GGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDG Sbjct: 241 GGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDG 300 Query: 301 GERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC 335 GERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC Sbjct: 301 GERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC 335 >gi|13540600 nudE nuclear distribution gene E homolog (A. nidulans)-like 1 isoform B [Homo sapiens] Length = 345 Score = 339 bits (870), Expect = 2e-93 Identities = 181/282 (64%), Positives = 226/282 (80%), Gaps = 8/282 (2%) Query: 8 FSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSE 67 FSS +EE YWK+L++ YKQ + ++EL EFQEGSRE EAELE QL Q E RNRDL ++ Sbjct: 9 FSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQAD 68 Query: 68 NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127 N RL+ E+E +KEK E Q+++ Y+Q+S LEDDL+QT+AIK+QL KY+RELEQANDDLERA Sbjct: 69 NQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERA 128 Query: 128 KRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQK-Q 186 KRATI+SLEDFEQRLNQAIERNAFLESELDEKE+LL SVQRLKDEARDLRQELAV+++ Q Sbjct: 129 KRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQ 188 Query: 187 EKPRTPMPSS--VEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDSTGGTP 244 E R PSS ++ E+ D+AVQA+ S+P+TP+ +G ++ +P + G G +P Sbjct: 189 EVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVG-KGTENTFPSPKAIPNGF----GTSP 243 Query: 245 LTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRT 286 LTP+ARISALNIVGDLLRKVGALESKLA+CRN DQ+ ++ Sbjct: 244 LTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKS 285 >gi|71284108 nudE nuclear distribution gene E homolog (A. nidulans)-like 1 isoform A [Homo sapiens] Length = 328 Score = 339 bits (870), Expect = 2e-93 Identities = 181/282 (64%), Positives = 226/282 (80%), Gaps = 8/282 (2%) Query: 8 FSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSE 67 FSS +EE YWK+L++ YKQ + ++EL EFQEGSRE EAELE QL Q E RNRDL ++ Sbjct: 9 FSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQAD 68 Query: 68 NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127 N RL+ E+E +KEK E Q+++ Y+Q+S LEDDL+QT+AIK+QL KY+RELEQANDDLERA Sbjct: 69 NQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERA 128 Query: 128 KRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQK-Q 186 KRATI+SLEDFEQRLNQAIERNAFLESELDEKE+LL SVQRLKDEARDLRQELAV+++ Q Sbjct: 129 KRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQ 188 Query: 187 EKPRTPMPSS--VEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDSTGGTP 244 E R PSS ++ E+ D+AVQA+ S+P+TP+ +G ++ +P + G G +P Sbjct: 189 EVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVG-KGTENTFPSPKAIPNGF----GTSP 243 Query: 245 LTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRT 286 LTP+ARISALNIVGDLLRKVGALESKLA+CRN DQ+ ++ Sbjct: 244 LTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKS 285 >gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] Length = 1976 Score = 62.4 bits (150), Expect = 6e-10 Identities = 50/197 (25%), Positives = 97/197 (49%), Gaps = 9/197 (4%) Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSE---N 68 EEE + +QR EEL E E ++ ++A LE Q +ET N++L E Sbjct: 1184 EEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVL 1243 Query: 69 NRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128 +++ E E ++K + Q E + ++S E D + + + ++ K EL+ + LE A+ Sbjct: 1244 QQVKAESEHKRKKLDAQVQELHAKVS--EGDRLRVE-LAEKASKLQNELDNVSTLLEEAE 1300 Query: 129 RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188 + I +D +Q + L+ E +K NL +++L++E L+++ Q+++E+ Sbjct: 1301 KKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQ---QEEEEE 1357 Query: 189 PRTPMPSSVEAERTDTA 205 R + V A ++ A Sbjct: 1358 ARKNLEKQVLALQSQLA 1374 Score = 50.4 bits (119), Expect = 2e-06 Identities = 54/231 (23%), Positives = 94/231 (40%), Gaps = 52/231 (22%) Query: 19 KDLAMTYKQRAENTQEELREFQ----------EGSREYEAELETQLQQIETRNRDLLSEN 68 K ++ Y + + + E RE + E + E + E E Q +Q+ DL+S Sbjct: 1461 KSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSK 1520 Query: 69 NRLRM---ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQ--------KYIREL 117 + + ELE K E Q E Q+ LED+L T+ K +L+ ++ R+L Sbjct: 1521 DDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDL 1580 Query: 118 EQANDDLERAKRATIMSLEDFEQRLNQAIERNAF-------LESELDEKENLLESVQRLK 170 + ++ E KR I + + E L ++ A +E +L + E +E+ + + Sbjct: 1581 QTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKAR 1640 Query: 171 DE---------------------ARDLRQELAVQQKQEKPRTPMPSSVEAE 200 DE AR R E+ Q K+ + + S+EAE Sbjct: 1641 DEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKL---KSLEAE 1688 Score = 47.0 bits (110), Expect = 2e-05 Identities = 44/177 (24%), Positives = 85/177 (48%), Gaps = 24/177 (13%) Query: 29 AENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSE 88 AE + L ++ E +LE+++++ E RN+ L +E +++ ++ ++E ++ E Sbjct: 906 AEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEE--QLDEEE 963 Query: 89 GYRQISALEDDLAQTK---------AIKDQLQKYIRELEQANDDLERAKRATIMSLEDFE 139 G RQ LE A+ K ++DQ K+I+E + D R + E+ E Sbjct: 964 GARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMED---RIAECSSQLAEEEE 1020 Query: 140 QRLNQAIERN--AFLESELDE--------KENLLESVQRLKDEARDLRQELAVQQKQ 186 + N A RN + S+L+E ++ L ++ ++L E DL+ ++A Q Q Sbjct: 1021 KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQ 1077 Score = 47.0 bits (110), Expect = 2e-05 Identities = 43/193 (22%), Positives = 81/193 (41%), Gaps = 13/193 (6%) Query: 14 EANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRM 73 + ++ + +A +++ + + L E + S Y E + + + LS L Sbjct: 1435 DLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEE 1494 Query: 74 ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIM 133 LE KE+FE RQ L D+ + KD + K + ELE++ LE+ Sbjct: 1495 ALEA-KEEFE-------RQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRT 1546 Query: 134 SLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPM 193 LE+ E L + LE + + E + +DE + ++ L ++Q +E + Sbjct: 1547 QLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRE-----L 1601 Query: 194 PSSVEAERTDTAV 206 + +E ER A+ Sbjct: 1602 EAELEDERKQRAL 1614 Score = 46.6 bits (109), Expect = 3e-05 Identities = 41/194 (21%), Positives = 88/194 (45%), Gaps = 14/194 (7%) Query: 2 EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGS-----------REYEAEL 50 +D GK E+ + + + E ++EL+ ++ ++E +L Sbjct: 1521 DDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDL 1580 Query: 51 ETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAI---K 107 +T+ +Q E + R L+ + L ELE +++ + + + L+D AQ +A + Sbjct: 1581 QTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKAR 1640 Query: 108 DQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQ 167 D++ K +R+L+ D +R S ++ + ++ ++ LE+E+ + + L S + Sbjct: 1641 DEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSE 1700 Query: 168 RLKDEARDLRQELA 181 R + A R ELA Sbjct: 1701 RARRHAEQERDELA 1714 Score = 45.4 bits (106), Expect = 7e-05 Identities = 46/183 (25%), Positives = 82/183 (44%), Gaps = 21/183 (11%) Query: 30 ENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEG 89 E +++ +F + + E++L+ + ++ R L+ ++R+R +LE K + Q E Sbjct: 1297 EEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIR-QLEEEKNSLQEQQEEE 1355 Query: 90 Y-------RQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRL 142 +Q+ AL+ LA TK D I LE+A L L+D E L Sbjct: 1356 EEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKL----------LKDAE-AL 1404 Query: 143 NQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEAERT 202 +Q +E A +L++ +N L+ Q L D DL + V EK + + E++ Sbjct: 1405 SQRLEEKALAYDKLEKTKNRLQ--QELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKS 1462 Query: 203 DTA 205 +A Sbjct: 1463 ISA 1465 Score = 42.0 bits (97), Expect = 8e-04 Identities = 31/141 (21%), Positives = 65/141 (46%), Gaps = 32/141 (22%) Query: 44 REYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQT 103 +E + ++E +L+++E +++ LL E N L +L+ E F A+ Sbjct: 865 KEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELF------------------AEA 906 Query: 104 KAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLL 163 + ++ +L +ELE+ L D E R+ + ERN L++E + + + Sbjct: 907 EEMRARLAAKKQELEEI--------------LHDLESRVEEEEERNQILQNEKKKMQAHI 952 Query: 164 ESVQRLKDEARDLRQELAVQQ 184 + ++ DE RQ+L +++ Sbjct: 953 QDLEEQLDEEEGARQKLQLEK 973 Score = 38.1 bits (87), Expect = 0.011 Identities = 36/195 (18%), Positives = 83/195 (42%), Gaps = 28/195 (14%) Query: 27 QRAENTQEELREFQEGSREYEAELETQLQQIETRNRDL---LSENNRLRMELETIKEKFE 83 +R + E + +E ++ +EA+++ Q+ T +L L + R + LE K+ E Sbjct: 1171 KREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLE 1230 Query: 84 VQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLN 143 + E ++ L+ A+++ + +L ++EL + +R + Sbjct: 1231 TDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRV-------------- 1276 Query: 144 QAIERNAFLESELDEKENLLESVQR-----------LKDEARDLRQELAVQQKQEKPRTP 192 + E+ + L++ELD LLE ++ L+ + +D ++ L + +Q+ + Sbjct: 1277 ELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSS 1336 Query: 193 MPSSVEAERTDTAVQ 207 +E E+ Q Sbjct: 1337 RIRQLEEEKNSLQEQ 1351 Score = 38.1 bits (87), Expect = 0.011 Identities = 41/192 (21%), Positives = 89/192 (46%), Gaps = 19/192 (9%) Query: 10 SEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69 +E++ + KD A + + + ++TQE L QE +R+ + L ++++Q+E L + Sbjct: 1299 AEKKGIKFAKDAA-SLESQLQDTQELL---QEETRQ-KLNLSSRIRQLEEEKNSLQEQQE 1353 Query: 70 RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ---------- 119 + ++++ S+ ++DDL +++++ +K +++ E Sbjct: 1354 EEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKAL 1413 Query: 120 ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLL---ESVQRLKDEARDL 176 A D LE+ K L+D L+ + + LE + + + LL +S+ E RD Sbjct: 1414 AYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERD- 1472 Query: 177 RQELAVQQKQEK 188 R E ++K+ K Sbjct: 1473 RAEAEAREKETK 1484 Score = 36.6 bits (83), Expect = 0.032 Identities = 44/227 (19%), Positives = 97/227 (42%), Gaps = 49/227 (21%) Query: 26 KQRAENTQEELREFQEGSREYEA---ELETQLQQIETRNRDLLSENNRLRMELETIKEKF 82 + R E +E + Q ++ +A +LE QL + E + L E +++ ++E+ Sbjct: 928 ESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEI 987 Query: 83 ---EVQHSEGYRQISALEDDLAQTKA---------------------IKDQLQKYIRELE 118 E Q+S+ ++ +ED +A+ + + L++ +++ E Sbjct: 988 LLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEE 1047 Query: 119 QANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKE------------------ 160 + +LE+AKR D + ++ + + L+ +L +KE Sbjct: 1048 KTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKN 1107 Query: 161 NLLESVQRLKDEARDLRQ----ELAVQQKQEKPRTPMPSSVEAERTD 203 N L+ V+ L+ + +L++ E A + K EK + + +EA +T+ Sbjct: 1108 NALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTE 1154 Score = 36.2 bits (82), Expect = 0.042 Identities = 41/204 (20%), Positives = 87/204 (42%), Gaps = 27/204 (13%) Query: 9 SSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEA---ELETQLQQIETRNRDLL 65 + EEE+A + + + +E L++ ++ +E E +L+ + ++ + +L Sbjct: 1016 AEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQ 1075 Query: 66 SENNRLRMELETIKEKFEVQHSEG-----------------YRQISALEDDLAQTKAIKD 108 ++ + L+++L +E+ + + G QI+ L++D KA ++ Sbjct: 1076 AQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRN 1135 Query: 109 QLQKYIR----ELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLE 164 + +K R ELE +LE T E +R + E LE +E +N Sbjct: 1136 KAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALE---EETKNHEA 1192 Query: 165 SVQRLKDEARDLRQELAVQQKQEK 188 +Q ++ +EL+ Q +Q K Sbjct: 1193 QIQDMRQRHATALEELSEQLEQAK 1216 Score = 35.4 bits (80), Expect = 0.072 Identities = 46/218 (21%), Positives = 92/218 (42%), Gaps = 23/218 (10%) Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL 71 EE+A + L T K R + ++L + R+ + LE + ++ + LL+E + Sbjct: 1409 EEKALAYDKLEKT-KNRLQQELDDLTVDLDHQRQVASNLEKKQKKFD----QLLAEEKSI 1463 Query: 72 RMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR-- 129 +++ E + E + +L L + K++ ++ ++L +DL +K Sbjct: 1464 SARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDV 1523 Query: 130 -ATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQ----- 183 + LE ++ L Q +E + ++L+E E+ L++ + K Q + Q Sbjct: 1524 GKNVHELEKSKRALEQQVEE---MRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDL 1580 Query: 184 -----QKQEKPRTPMPS--SVEAERTDTAVQATGSVPS 214 Q +EK R + +EAE D Q +V S Sbjct: 1581 QTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVAS 1618 Score = 34.3 bits (77), Expect = 0.16 Identities = 45/197 (22%), Positives = 72/197 (36%), Gaps = 54/197 (27%) Query: 28 RAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSE-----------------NNR 70 R +EEL E Q Q++T N +L +E N Sbjct: 1737 RIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKE 1796 Query: 71 LRMELE----TIKEKFEVQHSEGYRQISALEDDLAQT---------------KAIKD--- 108 L+ +L+ +K KF+ S +I LE+ L Q K +K+ Sbjct: 1797 LKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFM 1856 Query: 109 -------QLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDE--- 158 +Y ++E+AN +++ KR LE+ E+ +A L+ ELD+ Sbjct: 1857 QVEDERRHADQYKEQMEKANARMKQLKR----QLEEAEEEATRANASRRKLQRELDDATE 1912 Query: 159 -KENLLESVQRLKDEAR 174 E L V LK+ R Sbjct: 1913 ANEGLSREVSTLKNRLR 1929 >gi|114155142 nuclear pore complex-associated protein TPR [Homo sapiens] Length = 2363 Score = 59.7 bits (143), Expect = 4e-09 Identities = 59/228 (25%), Positives = 106/228 (46%), Gaps = 20/228 (8%) Query: 1 MEDSGKTFSSEEEE---ANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQI 57 ME S ++ +E+ ++L T Q AE + L E ++ +E ET+ + + Sbjct: 1456 METSAQSSGDHQEQHVSVQEMQELKETLNQ-AETKSKSLESQVENLQKTLSEKETEARNL 1514 Query: 58 ETRNRDLLSENNRLRMEL-------ETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQL 110 + + L SE +RLR +L E ++++ + + + I A + +A +KDQL Sbjct: 1515 QEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQL 1574 Query: 111 QKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDE-KENLLESVQRL 169 K EL+Q N L++ K + + + + I R LE EL E +E LE Sbjct: 1575 TKENEELKQRNGALDQQKDELDVRITALKSQYEGRISR---LERELREHQERHLEQ---- 1627 Query: 170 KDEARDLRQELAVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPI 217 +DE ++ ++ QQ+Q +T P+S E T+ T ++ TP+ Sbjct: 1628 RDEPQEPSNKVPEQQRQITLKT-TPASGERGIASTSDPPTANIKPTPV 1674 Score = 46.6 bits (109), Expect = 3e-05 Identities = 48/205 (23%), Positives = 90/205 (43%), Gaps = 24/205 (11%) Query: 25 YKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEV 84 + +R + EE+ + A L I++ DL N++R E ETI++ + Sbjct: 1364 HTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDL----NKVRTEKETIQKDLDA 1419 Query: 85 QHSEGYRQISALEDDL-------AQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLED 137 + + ++ + Q + +K Q K + Q++ D + + ++ +++ Sbjct: 1420 KIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGD-HQEQHVSVQEMQE 1478 Query: 138 FEQRLNQAIERNAFLESE-------LDEKE----NLLESVQRLKDEARDLRQELAVQQKQ 186 ++ LNQA ++ LES+ L EKE NL E +L+ E LRQ+L + Q Sbjct: 1479 LKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQ 1538 Query: 187 EKPRTPMPSSVEAERTDTAVQATGS 211 E+ + E E+T A+ A S Sbjct: 1539 EEQLRQQITEKE-EKTRKAIVAAKS 1562 Score = 43.5 bits (101), Expect = 3e-04 Identities = 46/227 (20%), Positives = 101/227 (44%), Gaps = 35/227 (15%) Query: 20 DLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNR--------DLLSENNRL 71 +L + K+ +N Q+E+ ++ E ++ +Q Q + + DL+S+ + Sbjct: 885 NLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQT 944 Query: 72 RMELETIKEKFEVQHS--EGYR-QISALEDDLAQTKAIKD------------------QL 110 ++ +KE+ + S E Y+ +++LE+ L + K + + QL Sbjct: 945 EEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQL 1004 Query: 111 QKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLK 170 +K + E+E+ +L+ KR I E EQ+L++ + + +++E+ E + + Sbjct: 1005 EKKLMEVEKEKQELQDDKRRAI---ESMEQQLSELKKTLSSVQNEVQEALQRASTALSNE 1061 Query: 171 DEARDLRQE---LAVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPS 214 +AR QE +AV+ + + R M + + E A + + S Sbjct: 1062 QQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMAS 1108 Score = 43.5 bits (101), Expect = 3e-04 Identities = 43/172 (25%), Positives = 76/172 (44%), Gaps = 21/172 (12%) Query: 22 AMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEK 81 ++ Y+QR E + EL+E Q+ S E E + ++ +L+ + + + +ET K Sbjct: 1221 SLRYRQRVELLERELQELQD-SLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKML 1279 Query: 82 FEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQR 141 E + LE DL Q +A +L+ I L++AN +L + E+ Sbjct: 1280 REEKER--------LEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEED 1331 Query: 142 LNQAIERNAFLESE------------LDEKENLLESVQRLKDEARDLRQELA 181 + + RN L S+ L EKE + +Q+L +E L+ E+A Sbjct: 1332 VKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIA 1383 Score = 42.0 bits (97), Expect = 8e-04 Identities = 49/219 (22%), Positives = 101/219 (46%), Gaps = 37/219 (16%) Query: 22 AMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEK 81 A+ K + QE +++ E E QL++++ + DL S+N ++ +L+ ++ Sbjct: 665 AIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKR 724 Query: 82 FEV--QHSEGY-RQISALEDDLAQTKAIKDQLQKYI----RELEQANDDL-------ERA 127 +E+ + EGY R+I++L + + A + ++ I ++L AN+ L E Sbjct: 725 YEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENL 784 Query: 128 KRATIMSLEDFEQRLNQAIE--------RNAFL-----------ESELDEKENLLESVQR 168 K+ M L+ E RL+Q E +N L SE + K+ L +++ Sbjct: 785 KKEKEM-LKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEK 843 Query: 169 LKDEARDLRQELAVQQKQEKPRTPMPSSVEAERTDTAVQ 207 L+ E L+++L + + + R + +++ + DT Q Sbjct: 844 LEHEISHLKKKL---ENEVEQRHTLTRNLDVQLLDTKRQ 879 Score = 41.6 bits (96), Expect = 0.001 Identities = 44/162 (27%), Positives = 77/162 (47%), Gaps = 28/162 (17%) Query: 34 EELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQI 93 +EL Q+ + +++ +++E RDL+ N RL ELE + E + Sbjct: 97 KELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTE-----------DV 145 Query: 94 SALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIE----RN 149 L + L ++ K +LQ + EL QA+D +S++ E+RL Q E +N Sbjct: 146 KRLNEKLKESNTTKGELQLKLDEL-QASD----------VSVKYREKRLEQEKELLHSQN 194 Query: 150 AFLESELDEKENLLESVQRLK-DEARDLRQELAVQQKQEKPR 190 +L +EL K + L ++ R K +E +L+ L +K+E R Sbjct: 195 TWLNTELKTKTDELLALGREKGNEILELKCNLE-NKKEEVSR 235 Score = 39.3 bits (90), Expect = 0.005 Identities = 33/145 (22%), Positives = 68/145 (46%), Gaps = 11/145 (7%) Query: 35 ELREFQEGSREYEAELETQLQQIETRNR-------DLLSENNRLRMELETIKEKFEVQHS 87 EL+ E +E + LE Q+ ++T N DLL++ + + +++EKF + + Sbjct: 221 ELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELN 280 Query: 88 EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQ--- 144 + + + ++A ++L + + EL + + A +A L + EQ +Q Sbjct: 281 AHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEK 340 Query: 145 -AIERNAFLESELDEKENLLESVQR 168 +E+ LE EL+ +LL + +R Sbjct: 341 EMLEKIGRLEKELENANDLLSATKR 365 Score = 36.6 bits (83), Expect = 0.032 Identities = 44/189 (23%), Positives = 84/189 (44%), Gaps = 28/189 (14%) Query: 7 TFSSEEEEANYWKDLAMTYK---QRAENTQEELREFQEGSREY---EAELETQLQQIET- 59 T + EE EA +DL T + Q E E+++ E +E + EL+ +L +++ Sbjct: 114 TRTKEELEAEK-RDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQAS 172 Query: 60 ------------RNRDLL-SENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAI 106 + ++LL S+N L EL+T ++ E +I L+ +L K Sbjct: 173 DVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEE 232 Query: 107 KDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESV 166 +L++ + L+ +N+ L++ +ED +L +A E+ A +E + + N + Sbjct: 233 VSRLEEQMNGLKTSNEHLQK-------HVEDLLTKLKEAKEQQASMEEKFHNELNAHIKL 285 Query: 167 QRLKDEARD 175 L A D Sbjct: 286 SNLYKSAAD 294 Score = 36.6 bits (83), Expect = 0.032 Identities = 37/188 (19%), Positives = 80/188 (42%), Gaps = 12/188 (6%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGS---REYEAELETQLQQI 57 +E + EE + + + E +E++ QE + + + LE +++ Sbjct: 430 VEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRM 489 Query: 58 ETRNRDLLSENNRLRMELETIKEKFEVQHSE-GYRQISALEDDLAQ-------TKAIKDQ 109 E + +DL + L MELE + ++ E IS+ + ++Q + ++ Q Sbjct: 490 EIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQ 549 Query: 110 LQKYIRELEQANDDLERAKRATIMS-LEDFEQRLNQAIERNAFLESELDEKENLLESVQR 168 Q+ + L + + ER ++ T S + + + +L A+ L + L++S+ R Sbjct: 550 NQRLLVALRELGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVR 609 Query: 169 LKDEARDL 176 +D R L Sbjct: 610 QRDMYRIL 617 Score = 36.6 bits (83), Expect = 0.032 Identities = 42/175 (24%), Positives = 72/175 (41%), Gaps = 14/175 (8%) Query: 9 SSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSEN 68 +S EE N K + ++ E +E EFQ + E+E + Q+++ R + Sbjct: 970 TSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESM 1029 Query: 69 NRLRMELETIKEKFEVQHSEGYRQIS--------ALEDDLAQTKAIKDQLQKYIRELEQA 120 + EL+ + + E ++ S A D Q K + KY REL Sbjct: 1030 EQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLH 1089 Query: 121 NDDLE--RAKRATIMSLEDFEQRLNQAIERNAFLESELDE-KENLLESVQRLKDE 172 D+E +A + + + Q L + ++ ES+L E K + E + LKDE Sbjct: 1090 AADVEALQAAKEQVSKMASVRQHLEETTQK---AESQLLECKASWEERERMLKDE 1141 Score = 36.2 bits (82), Expect = 0.042 Identities = 38/153 (24%), Positives = 68/153 (44%), Gaps = 8/153 (5%) Query: 38 EFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALE 97 +F+ S + E+E +L + R + E LR+ELE + + + +E +++ + Sbjct: 45 KFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKAL-TEKNKELEIAQ 103 Query: 98 DDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLE---DFEQRLNQAIERNAFLES 154 D + AI+ Q + ELE DL R LE + +RLN+ ++ + + Sbjct: 104 D---RNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKG 160 Query: 155 ELDEK-ENLLESVQRLKDEARDLRQELAVQQKQ 186 EL K + L S +K + L QE + Q Sbjct: 161 ELQLKLDELQASDVSVKYREKRLEQEKELLHSQ 193 Score = 32.7 bits (73), Expect = 0.47 Identities = 34/133 (25%), Positives = 65/133 (48%), Gaps = 13/133 (9%) Query: 55 QQIETRNRDLLSENNRLRMELETIK--EKFEVQHSEGYRQISALEDDLAQTKAIKDQLQK 112 Q++E R+L + L E E ++ K QH E ++ + + K ++++ ++ Sbjct: 1226 QRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKER 1285 Query: 113 YIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDE 172 ++L+Q + R I+ L++ L+ E++ L++ EK+ L E V+R K Sbjct: 1286 LEQDLQQMQAKV-RKLELDILPLQEANAELS---EKSGMLQA---EKKLLEEDVKRWK-- 1336 Query: 173 ARDLRQELAVQQK 185 AR+ Q L QQK Sbjct: 1337 ARN--QHLVSQQK 1347 Score = 30.4 bits (67), Expect = 2.3 Identities = 28/159 (17%), Positives = 64/159 (40%), Gaps = 12/159 (7%) Query: 40 QEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDD 99 + E + L +Q++++E L + + T+ +VQ + RQ+ + Sbjct: 827 ERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNL 886 Query: 100 LAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEK 159 TK + QK I L+Q ++E + QR + N ++ Sbjct: 887 HLNTKELLKNAQKEIATLKQHLSNME------VQVASQSSQRTGKGQPSNK------EDV 934 Query: 160 ENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVE 198 ++L+ +++ +++ DL++ L + M +S+E Sbjct: 935 DDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLE 973 >gi|31982906 cingulin-like 1 [Homo sapiens] Length = 1302 Score = 59.3 bits (142), Expect = 5e-09 Identities = 46/178 (25%), Positives = 82/178 (46%), Gaps = 4/178 (2%) Query: 30 ENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEG 89 E Q+E+ + E SR EL+ QL + + +NR L+E R E EK + + Sbjct: 951 EKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKM 1010 Query: 90 YRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERN 149 ++ +E++L + +D+ + LEQ DLE A +D + + Q ++ Sbjct: 1011 QDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKV 1070 Query: 150 AFLESELDEKEN----LLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEAERTD 203 + LE EL+E+ N L E + R +++ LR EL ++ + S+E + D Sbjct: 1071 SQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQNKD 1128 Score = 54.7 bits (130), Expect = 1e-07 Identities = 61/228 (26%), Positives = 97/228 (42%), Gaps = 12/228 (5%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 MED E EE DL R+ E+LR R +LE +E + Sbjct: 1066 MEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQ 1125 Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120 N+DL S L + KE VQ +I+ LED L + + LQ R LE+ Sbjct: 1126 NKDLKSRIIHLEGSYRSSKEGLVVQME---ARIAELEDRLESEERDRANLQLSNRRLERK 1182 Query: 121 NDDLERAKRATIMSLEDFEQRLN---QAIERNA-FLESELDEKENLLESVQRLKDEARDL 176 +L +SL D + +L+ +A++R E E+D E+ + +QR +E D+ Sbjct: 1183 VKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDM 1242 Query: 177 RQELAVQ---QKQEKPRTPMPSSVEAERTDTAVQAT--GSVPSTPIAH 219 + L Q K++ +PS V + D +T GS+ P+++ Sbjct: 1243 NEHLQGQLNSMKKDLRLKKLPSKVLDDMDDDDDLSTDGGSLYEAPVSY 1290 Score = 47.4 bits (111), Expect = 2e-05 Identities = 45/181 (24%), Positives = 91/181 (50%), Gaps = 19/181 (10%) Query: 28 RAENTQEELREFQEGSREYE---AELETQLQQIETRNRDLLSENNRLRMELETIKEKFEV 84 +A N+ E+++ E + AEL+ QLQ +++ E R+R LE ++ Sbjct: 601 QACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRS---- 656 Query: 85 QHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQ 144 QH+E + S L+ L +++ +L+K + EL Q +ER + T + D + +L++ Sbjct: 657 QHNEKVEENSTLQQRLEESEG---ELRKNLEELFQVK--MEREQHQT--EIRDLQDQLSE 709 Query: 145 A-IERNAFLESELDEKENLLESVQRLKDEARDL----RQELAVQQKQEKPRTPMPSSVEA 199 E ++ SE EK L+E + + K + +DL ++ + +K+E+ T + +++ Sbjct: 710 MHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKE 769 Query: 200 E 200 E Sbjct: 770 E 770 Score = 45.4 bits (106), Expect = 7e-05 Identities = 50/193 (25%), Positives = 83/193 (43%), Gaps = 25/193 (12%) Query: 30 ENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRM------ELETIKEKFE 83 E EL+ +E E +E + T +D R+++ +L+ E+ E Sbjct: 783 EQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELE 842 Query: 84 VQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA-------NDDLERAKRATIMSLE 136 + ++ RQI L+ D A+ K + + IR+LE+A + A+RA LE Sbjct: 843 RRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELE 902 Query: 137 DFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ-----EKPRT 191 + L+Q + L +L E ES Q K++ R L+ E+ ++ EK + Sbjct: 903 AAQGNLSQTTQEQKQLSEKLKE-----ESEQ--KEQLRRLKNEMENERWHLGKTIEKLQK 955 Query: 192 PMPSSVEAERTDT 204 M VEA RT T Sbjct: 956 EMADIVEASRTST 968 Score = 45.1 bits (105), Expect = 9e-05 Identities = 38/174 (21%), Positives = 79/174 (45%), Gaps = 2/174 (1%) Query: 40 QEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDD 99 Q+ +E + L+++ +++ + + EN+ L+ LE + + E ++ E Sbjct: 637 QQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQH 696 Query: 100 LAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEK 159 + + ++DQL + EL+ A +R K A I L +Q L + E L ++ Sbjct: 697 QTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKR 756 Query: 160 ENLLESVQ-RLKDEARDLRQEL-AVQQKQEKPRTPMPSSVEAERTDTAVQATGS 211 E L +++ LK+E QE+ ++++ + + SVE + V A+ S Sbjct: 757 ERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRS 810 Score = 38.9 bits (89), Expect = 0.007 Identities = 39/184 (21%), Positives = 81/184 (44%), Gaps = 6/184 (3%) Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85 ++R EELR E + L+ +L++ E R L E +++ME +E+ + + Sbjct: 644 RERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKME----REQHQTE 699 Query: 86 HSEGYRQISALEDDLAQTKAIKDQLQ-KYIRELEQANDDLERAKRATIMSLEDFEQRLNQ 144 + Q+S + D+L K +D+ + I EL QA DL+ A + +R + Sbjct: 700 IRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERE 759 Query: 145 AIERNAFLESELDEKENLLESVQRLKD-EARDLRQELAVQQKQEKPRTPMPSSVEAERTD 203 L+ E+ + ++ ++ D E + LR+ + K + ++ E ++ Sbjct: 760 LTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAG 819 Query: 204 TAVQ 207 T ++ Sbjct: 820 TEMR 823 Score = 37.7 bits (86), Expect = 0.015 Identities = 44/198 (22%), Positives = 85/198 (42%), Gaps = 43/198 (21%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 M+D + E + +D A+T +Q E T ++L EYE E ++ L+ Sbjct: 1010 MQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDL--------EYELEAKSHLKD---- 1057 Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120 + +RL ++E + E++ E L + +++++ +QL+ + + A Sbjct: 1058 ------DRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAA 1111 Query: 121 NDDLERAK----------RATIMSLE------------DFEQRLNQAIERNAFLESELDE 158 DLE K ++ I+ LE E R+ + +R LESE + Sbjct: 1112 RQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDR---LESEERD 1168 Query: 159 KENLLESVQRLKDEARDL 176 + NL S +RL+ + ++L Sbjct: 1169 RANLQLSNRRLERKVKEL 1186 Score = 33.5 bits (75), Expect = 0.27 Identities = 31/171 (18%), Positives = 71/171 (41%), Gaps = 4/171 (2%) Query: 34 EELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQI 93 EEL + ++ ++ E Q + R R+L + L+ E+ + ++ + + ++ Sbjct: 730 EELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAEL 789 Query: 94 SALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLE 153 AL + + + + L EQ E + E + R + R A L+ Sbjct: 790 QALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQ 849 Query: 154 SELD----EKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEAE 200 +++ ++ E++++ + E R L + L +K+EK ++E E Sbjct: 850 RQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENE 900 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 58.9 bits (141), Expect = 6e-09 Identities = 54/231 (23%), Positives = 96/231 (41%), Gaps = 20/231 (8%) Query: 2 EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRN 61 +D + +EE+A + L +++ QE L+ ++ R+ E E + ++ E R Sbjct: 427 KDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERR 486 Query: 62 RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQ-LQKYIRELEQA 120 R++ E RL+ LE +DD K + LQK +R+ E+ Sbjct: 487 REMAKEAKRLKEFLEDY------------------DDDRDDPKYYRGSALQKRLRDREKE 528 Query: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180 + ER ++ LE+ QRL + E + E+E ++K E +E Sbjct: 529 MEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEE 588 Query: 181 AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTP-IAHRGPSSSLNTPG 230 Q+K+EK PM E E+ + S P ++ +++ NTPG Sbjct: 589 EKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPG 639 Score = 39.7 bits (91), Expect = 0.004 Identities = 55/229 (24%), Positives = 99/229 (43%), Gaps = 23/229 (10%) Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQ--------EGSREYEAELETQLQQIETRNR 62 EEE+ K+ K+R E +E RE + E RE E E E + ++ R+R Sbjct: 292 EEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDR 351 Query: 63 DLLSENNRLR---MELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ 119 D E +R R + + +E+ ++ + R D + + +++ ++ RE E+ Sbjct: 352 DRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERER 411 Query: 120 AND---DLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKD----E 172 + + ER + D E+ A ER LE +L EKE + +RLK+ E Sbjct: 412 EREREREREREREREKDKKRDREEDEEDAYERRK-LERKLREKEAAYQ--ERLKNWEIRE 468 Query: 173 ARDLRQELAVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRG 221 + R+ +++E+ R M + EA+R ++ P +RG Sbjct: 469 RKKTREYEKEAEREEERRREM--AKEAKRLKEFLEDYDDDRDDPKYYRG 515 >gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] Length = 1979 Score = 57.8 bits (138), Expect = 1e-08 Identities = 42/171 (24%), Positives = 92/171 (53%), Gaps = 21/171 (12%) Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLS---ENNRLRMELETIKEK- 81 K+R+ QEEL ++ + R+ E +T IE ++R L S ENN L+ ELE ++E+ Sbjct: 821 KERSSKLQEELDKYSQALRKNEILRQT----IEEKDRSLGSMKEENNHLQEELERLREEQ 876 Query: 82 ---FEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDF 138 V + ++ L +++Q IK+ L++ I+ ++ +D ++K + SL++ Sbjct: 877 SRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQ 936 Query: 139 EQRLNQ---------AIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180 ++ +++ A FLE + +E ++L ++++++K + + RQ++ Sbjct: 937 KKEMDEFRYQHEQMNATHTQLFLEKD-EEIKSLQKTIEQIKTQLHEERQDI 986 Score = 44.3 bits (103), Expect = 2e-04 Identities = 28/130 (21%), Positives = 61/130 (46%), Gaps = 2/130 (1%) Query: 11 EEEEANYWKD-LAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69 E +E Y + + T+ Q EE++ Q+ + + +L + Q I+T N D+ E Sbjct: 939 EMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETK 998 Query: 70 RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR 129 + +E EK ++ +E R + +++ + K + ++ ++++Q + D E K Sbjct: 999 VQSLNIENGSEKHDLSKAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKD-EVGKL 1057 Query: 130 ATIMSLEDFE 139 I+ +D E Sbjct: 1058 TQIIQQKDLE 1067 Score = 43.5 bits (101), Expect = 3e-04 Identities = 41/204 (20%), Positives = 92/204 (45%), Gaps = 16/204 (7%) Query: 6 KTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLL 65 +T+ +E E ++ M + + E +E + +E Q ++ + + Sbjct: 1470 ETYRGKETEYQALQETNMKFSMMLREKEFECHSMKEKALAFE-------QLLKEKEQGKT 1522 Query: 66 SENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLE 125 E N+L +++++EK V E + + AL+ + A+++++Q+ + ++N +LE Sbjct: 1523 GELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKEFRSNQELE 1582 Query: 126 RAKRATIMSLEDFEQRLNQAIERNA-------FLESELDEKENLLESV-QRLKDEARDLR 177 R + + S + + + A +R A LE +L N +E+ + + L+ Sbjct: 1583 RLRNHLLESEDSYTREALAAEDREAKLRKKVTVLEEKLVSSSNAMENASHQASVQVESLQ 1642 Query: 178 QELAVQQKQEKPRTPMPSSVEAER 201 ++L V KQ + T + SV E+ Sbjct: 1643 EQLNVVSKQ-RDETALQLSVSQEQ 1665 Score = 42.4 bits (98), Expect = 6e-04 Identities = 39/163 (23%), Positives = 81/163 (49%), Gaps = 4/163 (2%) Query: 20 DLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIK 79 DL + + + + + + E + E E EL+ Q Q+ + + ++ + E ++I Sbjct: 471 DLRLNLEAKEQELNQSISEKETLIAEIE-ELDRQNQEATKHMILIKDQLSKQQNEGDSII 529 Query: 80 EKFEVQHSEGYRQISALEDD-LAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDF 138 K + ++ +++ LEDD + TK + Q +K I+ E A +DL K+ +E+ Sbjct: 530 SKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQS-EVALNDLHLTKQKLEDKVENL 588 Query: 139 EQRLNQAIERNAFLESE-LDEKENLLESVQRLKDEARDLRQEL 180 +LN++ E N ++ E L+ KE++ ++ + L +L Q L Sbjct: 589 VDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSL 631 Score = 40.8 bits (94), Expect = 0.002 Identities = 33/161 (20%), Positives = 73/161 (45%), Gaps = 18/161 (11%) Query: 34 EELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQI 93 EE ++++ E ++ + L+ N + ME+ +K+ E ++ Sbjct: 734 EEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETK 793 Query: 94 SALEDDLAQTKAIKDQLQK---YIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNA 150 L L + K + + K +I +L++ + L+ E+ + + +QA+ +N Sbjct: 794 DVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQ----------EELD-KYSQALRKNE 842 Query: 151 FLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRT 191 L ++EK+ L S +K+E L++EL + ++E+ RT Sbjct: 843 ILRQTIEEKDRSLGS---MKEENNHLQEELE-RLREEQSRT 879 Score = 39.7 bits (91), Expect = 0.004 Identities = 30/88 (34%), Positives = 48/88 (54%), Gaps = 8/88 (9%) Query: 41 EGSREYEAEL-ETQLQQIETRNRDLLSENNRLRMELETIKEKFEV------QHSEGYR-Q 92 EG+ E EAEL +++ ++IE + L SEN RL+ ++EK E Q S YR Q Sbjct: 40 EGTEEVEAELPDSRTKEIEAIHAILRSENERLKKLCTDLEEKHEASEIQIKQQSTSYRNQ 99 Query: 93 ISALEDDLAQTKAIKDQLQKYIRELEQA 120 + E +++ KA + LQ + +L+ A Sbjct: 100 LQQKEVEISHLKARQIALQDQLLKLQSA 127 Score = 37.4 bits (85), Expect = 0.019 Identities = 44/170 (25%), Positives = 76/170 (44%), Gaps = 26/170 (15%) Query: 34 EELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQI 93 +E E Q + E E ++ TR+ L SE + LR+ LE +++ SE I Sbjct: 436 QEKEELQMSLLKLNNEYEV-IKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLI 494 Query: 94 SALEDDLAQTK-------AIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAI 146 + +E+ Q + IKDQL K E + L++ L D ++R++Q Sbjct: 495 AEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQ-------DLNDEKKRVHQLE 547 Query: 147 ERNAFLESELD-EKENLLES----------VQRLKDEARDLRQELAVQQK 185 + + ELD +KE L++S Q+L+D+ +L +L Q+ Sbjct: 548 DDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQE 597 Score = 35.4 bits (80), Expect = 0.072 Identities = 41/160 (25%), Positives = 72/160 (45%), Gaps = 26/160 (16%) Query: 34 EELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQI 93 E L E E ++ EL LQ+ + R L N+RL + E +H + Sbjct: 1336 EVLSESSELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQ----- 1390 Query: 94 SALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSL-EDFEQRLN------QAI 146 + ++ Q K +D LQK ++E D L +AK ++S E+F ++N QA+ Sbjct: 1391 --TDSEIKQLKEKQDVLQKLLKE----KDLLIKAKSDQLLSSNENFTNKVNENELLRQAV 1444 Query: 147 ----ERNAFLESEL----DEKENLLESVQRLKDEARDLRQ 178 ER LE ++ E E ++E+ + + E + L++ Sbjct: 1445 TNLKERILILEMDIGKLKGENEKIVETYRGKETEYQALQE 1484 Score = 35.0 bits (79), Expect = 0.094 Identities = 43/197 (21%), Positives = 79/197 (40%), Gaps = 38/197 (19%) Query: 12 EEEANYWKDLAMTYKQRA--------------------ENTQEELREFQEGSREYEAELE 51 E E +W+ +A T K + +N +E+ + Q + + Sbjct: 185 ESEVGHWRHIAQTSKAQGTDNSDQSEICKLQNIIKELKQNRSQEIDDHQHEMSVLQNAHQ 244 Query: 52 TQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQ 111 +L +I R+R+ LS+ ELE + + Q G +E DL++ ++Q Sbjct: 245 QKLTEISRRHREELSDYEERIEELENLLQ----QGGSG-----VIETDLSKIY----EMQ 291 Query: 112 KYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELD----EKENLLESVQ 167 K I+ L+ + + ++D ++L+ A L E + EK ++E + Sbjct: 292 KTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECE 351 Query: 168 RLKDEARDLRQELAVQQ 184 LK E L Q AV+Q Sbjct: 352 NLKLECSKL-QPSAVKQ 367 Score = 28.9 bits (63), Expect = 6.8 Identities = 41/203 (20%), Positives = 87/203 (42%), Gaps = 34/203 (16%) Query: 31 NTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIK----------E 80 N EEL + ++ ++ ++E QQ+ T +++ E+ +L+ EL ++ Sbjct: 1202 NQFEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVLVDSDNNS 1261 Query: 81 KFEVQHS---EGYRQ----ISALEDDLAQTKAIKDQL----QKYIRELEQANDDLERAKR 129 K +V ++ + Y Q + +LAQ + QL + +L+ + L A Sbjct: 1262 KLQVDYTGLIQSYEQNETKLKNFGQELAQVQHSIGQLCNTKDLLLGKLDIISPQLSSASL 1321 Query: 130 ATIMSLEDFEQRLNQAI-ERNAFLESELDEKENLLE----SVQRLKDEARDLRQELAVQQ 184 T S E ++ + E + L+ EL+E L+ +++ L++ L +A Sbjct: 1322 LTPQSAECLRASKSEVLSESSELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATS 1381 Query: 185 KQEKPRTPMPSSVEAERTDTAVQ 207 + E+ E E+TD+ ++ Sbjct: 1382 ELERK--------EHEQTDSEIK 1396 >gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] Length = 1960 Score = 56.2 bits (134), Expect = 4e-08 Identities = 50/195 (25%), Positives = 87/195 (44%), Gaps = 28/195 (14%) Query: 19 KDLAMTYKQRAENTQEELREFQ----------EGSREYEAELETQLQQIETRNRDLLSEN 68 K ++ Y + + + E RE + E + E +AELE +Q T DL+S Sbjct: 1454 KTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSK 1513 Query: 69 NRLRM---ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQ--------KYIREL 117 + + ELE K E Q E Q+ LED+L T+ K +L+ ++ R+L Sbjct: 1514 DDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDL 1573 Query: 118 EQANDDLERAKRATIMS-------LEDFEQRLNQAIERNAFLESELDEKENLLESVQRLK 170 + ++ E K+ + LED ++ + A+ LE +L + E ++S + + Sbjct: 1574 QGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNR 1633 Query: 171 DEARDLRQELAVQQK 185 DEA ++L Q K Sbjct: 1634 DEAIKQLRKLQAQMK 1648 Score = 49.3 bits (116), Expect = 5e-06 Identities = 46/204 (22%), Positives = 92/204 (45%), Gaps = 6/204 (2%) Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL 71 EEEA + +Q+ EEL E E ++ +A LE Q +E +L +E L Sbjct: 1177 EEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVL 1236 Query: 72 ---RMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128 + + E ++K E Q E Q+ E + +T+ + D++ K EL+ L ++ Sbjct: 1237 LQGKGDSEHKRKKVEAQLQE--LQVKFNEGERVRTE-LADKVTKLQVELDNVTGLLSQSD 1293 Query: 129 RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188 + +DF +Q + L+ E +K +L +++++DE R++L +++ + Sbjct: 1294 SKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKH 1353 Query: 189 PRTPMPSSVEAERTDTAVQATGSV 212 +++ A+ D + SV Sbjct: 1354 NLEKQIATLHAQVADMKKKMEDSV 1377 Score = 48.1 bits (113), Expect = 1e-05 Identities = 49/207 (23%), Positives = 89/207 (42%), Gaps = 27/207 (13%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 +E K F +E E+ KD E ++ L + E + ELE +LQ E Sbjct: 1495 LERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATE-- 1552 Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120 RL + L+ +K +FE R + ++ Q++ K QL + +RE+E Sbjct: 1553 -----DAKLRLEVNLQAMKAQFE-------RDLQGRDE---QSEEKKKQLVRQVREMEAE 1597 Query: 121 NDDLER-------AKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEA 173 +D + A++ M L+D E ++ A + +L + + ++ R D+ Sbjct: 1598 LEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDT 1657 Query: 174 RDLRQELAVQQKQEKPRTPMPSSVEAE 200 R R+E+ Q K+ + + S+EAE Sbjct: 1658 RASREEILAQAKENEKKL---KSMEAE 1681 Score = 47.8 bits (112), Expect = 1e-05 Identities = 49/192 (25%), Positives = 81/192 (42%), Gaps = 16/192 (8%) Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYE------AELETQLQQIETRNRDLL 65 EEE +D + + ++ + EF E E A+L+ + + + T + L Sbjct: 977 EEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERL 1036 Query: 66 SENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLE 125 + R ELE + K E ++ QI+ L+ +A+ +K QL K EL+ A +E Sbjct: 1037 RREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAE---LKMQLAKKEEELQAALARVE 1093 Query: 126 RAKRATIMSLEDFEQRLNQAIERNAFLESEL-------DEKENLLESVQRLKDEARDLRQ 178 M+L+ + +Q E LESE +K +L E ++ LK E D Sbjct: 1094 EEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLD 1153 Query: 179 ELAVQQKQEKPR 190 A QQ+ R Sbjct: 1154 STAAQQELRSKR 1165 Score = 45.4 bits (106), Expect = 7e-05 Identities = 45/194 (23%), Positives = 81/194 (41%), Gaps = 14/194 (7%) Query: 2 EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIET-- 59 +D GK+ E+ + K + E ++EL+ ++ E L+ Q E Sbjct: 1514 DDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDL 1573 Query: 60 RNRDLLSENNRLRM-----ELETIKEKFEVQHSEGYRQISALEDDLAQTKAI-------K 107 + RD SE + ++ E+E E Q S LE DL +A + Sbjct: 1574 QGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNR 1633 Query: 108 DQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQ 167 D+ K +R+L+ D R T S E+ + + ++ +E+E+ + + L + + Sbjct: 1634 DEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAE 1693 Query: 168 RLKDEARDLRQELA 181 R K +A+ R ELA Sbjct: 1694 RAKRQAQQERDELA 1707 Score = 42.0 bits (97), Expect = 8e-04 Identities = 42/201 (20%), Positives = 93/201 (46%), Gaps = 29/201 (14%) Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEK---F 82 ++R ++ Q E ++ Q+ +E LE QL++ E+ + L E +L+ ++E+ Sbjct: 928 EERCQHLQAEKKKMQQNIQE----LEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIIL 983 Query: 83 EVQHSEGYRQISALEDDLAQ---------------------TKAIKDQLQKYIRELEQAN 121 E Q+ + ++ LED +A+ +A+ L++ +R E+ Sbjct: 984 EDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQR 1043 Query: 122 DDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLE-SVQRLKDEARDLRQEL 180 +LE+ +R D ++ + + A L+ +L +KE L+ ++ R+++EA L Sbjct: 1044 QELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMAL 1103 Query: 181 AVQQKQEKPRTPMPSSVEAER 201 ++ E + + +E+ER Sbjct: 1104 KKIRELESQISELQEDLESER 1124 Score = 41.6 bits (96), Expect = 0.001 Identities = 41/187 (21%), Positives = 81/187 (43%), Gaps = 8/187 (4%) Query: 26 KQRAENTQEELREFQEGSR-EYEAELETQLQQIETRNRDLLSEN---NRLRMELETIKEK 81 + +AE + +L E E + E E L++ Q E R++ N L E +T + + Sbjct: 1127 RNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQ 1186 Query: 82 FEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQR 141 + + + + L + L QTK +K L+K + LE +L + + D E + Sbjct: 1187 IQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHK 1246 Query: 142 LNQAIERNAFLESELDEKE----NLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSV 197 + + L+ + +E E L + V +L+ E ++ L+ + T S++ Sbjct: 1247 RKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSAL 1306 Query: 198 EAERTDT 204 E++ DT Sbjct: 1307 ESQLQDT 1313 Score = 41.2 bits (95), Expect = 0.001 Identities = 37/170 (21%), Positives = 81/170 (47%), Gaps = 10/170 (5%) Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85 +Q E T+ +L + AEL+ Q+ +++ + L + L+ L ++E+ + Sbjct: 1043 RQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQ---LAKKEEELQAALARVEEEAAQK 1099 Query: 86 HS------EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFE 139 + E QIS L++DL +A +++ +K R+L + + L+ T+ S + Sbjct: 1100 NMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159 Query: 140 QRLNQAIERNAFLESELDEKENLLES-VQRLKDEARDLRQELAVQQKQEK 188 + ++ + L+ L+E+ E+ +Q ++ + +ELA Q +Q K Sbjct: 1160 ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTK 1209 Score = 40.8 bits (94), Expect = 0.002 Identities = 61/302 (20%), Positives = 119/302 (39%), Gaps = 29/302 (9%) Query: 30 ENTQEELREFQEGSREYEAE---LETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQH 86 E + +E ++ + EAE L+ +L E R E + L E+ K + Sbjct: 1662 EEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALAL 1721 Query: 87 SEGYR---QISALEDDLAQ----TKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFE 139 E R +I+ LE++L + T+ I D+L+K +++Q N DL +R+ E+ Sbjct: 1722 EEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDL-NLERSHAQKNENAR 1780 Query: 140 QRLNQAIERNAFLESELDEKENLLE-----SVQRLKDEARDLRQELAVQQKQEKPRTPMP 194 Q+L + +N L+ +L E E ++ S+ L+ + L ++L + K+ + Sbjct: 1781 QQLER---QNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQV 1837 Query: 195 SSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDSTGGTPLTPAARISAL 254 E + D +Q + + +R L+++ A+R Sbjct: 1838 RRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQ 1897 Query: 255 NIVGDLLRKVGALESKLASCRNLVYDQS-----PNRTGGPASGRSSKNR-----DGGERR 304 + D A+ +++S +N + P R +G S DG E + Sbjct: 1898 RELEDATETADAMNREVSSLKNKLRRGDLPFVVPRRMARKGAGDGSDEEVDGKADGAEAK 1957 Query: 305 PS 306 P+ Sbjct: 1958 PA 1959 Score = 39.3 bits (90), Expect = 0.005 Identities = 29/128 (22%), Positives = 65/128 (50%), Gaps = 8/128 (6%) Query: 43 SREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQ 102 SR+ E + + + ++ R + L +EN E+ET++ + + + Q+ A + A+ Sbjct: 841 SRQEEEMMAKEEELVKVREKQLAAENRLT--EMETLQSQLMAEKLQLQEQLQAETELCAE 898 Query: 103 TKAIKDQLQKYIRELEQANDDLE---RAKRATIMSLEDFEQRLNQAIERNAFLESELDEK 159 + ++ +L +ELE+ DLE + L+ ++++ Q I+ LE +L+E+ Sbjct: 899 AEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQE---LEEQLEEE 955 Query: 160 ENLLESVQ 167 E+ + +Q Sbjct: 956 ESARQKLQ 963 Score = 38.9 bits (89), Expect = 0.007 Identities = 47/198 (23%), Positives = 83/198 (41%), Gaps = 19/198 (9%) Query: 4 SGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRN-- 61 +G S+ + + KD + Q ++TQE L+E + L T+L+Q+E Sbjct: 1286 TGLLSQSDSKSSKLTKDFSALESQ-LQDTQELLQE----ENRQKLSLSTKLKQVEDEKNS 1340 Query: 62 -RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ- 119 R+ L E + LE Q ++ +++ L + +K +LQK + L Q Sbjct: 1341 FREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQR 1400 Query: 120 ------ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLL---ESVQRLK 170 A D LE+ K L+D L+ + LE + + + LL +++ Sbjct: 1401 HEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKY 1460 Query: 171 DEARDLRQELAVQQKQEK 188 E RD R E ++K+ K Sbjct: 1461 AEERD-RAEAEAREKETK 1477 Score = 37.7 bits (86), Expect = 0.015 Identities = 43/194 (22%), Positives = 84/194 (43%), Gaps = 25/194 (12%) Query: 14 EANYWKDLAMTYKQRAENTQEELREFQEGSREYEAE---LETQLQQIETRNRDL---LSE 67 + ++ + A +++ + + L E + S +Y E E + ++ ET+ L L E Sbjct: 1428 DLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEE 1487 Query: 68 NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127 + ELE + ++F + +ED ++ KD + K + ELE++ LE+ Sbjct: 1488 AMEQKAELERLNKQFRTE----------MEDLMSS----KDDVGKSVHELEKSKRALEQQ 1533 Query: 128 KRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQE 187 LE+ E L + LE L + E + +DE + +++ V+Q +E Sbjct: 1534 VEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE 1593 Query: 188 KPRTPMPSSVEAER 201 M + +E ER Sbjct: 1594 -----MEAELEDER 1602 Score = 33.9 bits (76), Expect = 0.21 Identities = 52/206 (25%), Positives = 82/206 (39%), Gaps = 49/206 (23%) Query: 21 LAMTYKQRAE----NTQEELREFQEGSREYEAELETQLQQIETRNRDL--------LSEN 68 LA+ K+R E +EEL E Q + L+ QI+ N DL +EN Sbjct: 1719 LALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNEN 1778 Query: 69 NRLRMELETIKEKFEVQHSEG-----YR-QISALEDDLAQT------------------- 103 R ++E + + K ++Q EG Y+ I+ALE +AQ Sbjct: 1779 ARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVR 1838 Query: 104 ---KAIKD---QLQKYIRELEQANDDLERAK---RATIMSLEDFEQRLNQAIERNAFLES 154 K +KD Q+ R EQ D ++A + LE+ E+ +A L+ Sbjct: 1839 RTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQR 1898 Query: 155 ELDEKENLLESVQRLKDEARDLRQEL 180 EL E+ E+ + E L+ +L Sbjct: 1899 EL---EDATETADAMNREVSSLKNKL 1921 Score = 31.6 bits (70), Expect = 1.0 Identities = 16/72 (22%), Positives = 34/72 (47%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 ++D + +++A+ K++ E +EE + R+ + ELE + + Sbjct: 1851 VDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAM 1910 Query: 61 NRDLLSENNRLR 72 NR++ S N+LR Sbjct: 1911 NREVSSLKNKLR 1922 >gi|145312241 differentially expressed in FDCP 6 homolog [Homo sapiens] Length = 631 Score = 56.2 bits (134), Expect = 4e-08 Identities = 77/337 (22%), Positives = 134/337 (39%), Gaps = 61/337 (18%) Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL 71 E + + KDL ++ Q E RE + ++E E QLQ+ + R L Sbjct: 316 EGKTSLHKDLKQKRRE-----QREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEA 370 Query: 72 RMELETIKEKFEVQHSEGYRQIS-ALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRA 130 + + E + ++ E + +R++ ALE L + + + +Q E+E ++ R +R Sbjct: 371 QRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQA---EMELKEEEAAR-QRQ 426 Query: 131 TIMSLEDFEQRLNQAIE---------------RNAFLESELDEKENLLE-------SVQR 168 I LE+ +QRL +A++ + LE E ++ + L++ ++R Sbjct: 427 RIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLKEEQERYIER 486 Query: 169 LKDEARDLRQELA-----VQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPS 223 + E +L+QE+A +QQ Q++ + A+ A Q ST + H Sbjct: 487 AQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEAAQRKLRQASTNVKHWNVQ 546 Query: 224 SSL----NTPGSFRRGLDDS-TGGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLV 278 + PG R S +G P A R S+L R Sbjct: 547 MNRLMHPIEPGDKRPVTSSSFSGFQPPLLAHRDSSLK-------------------RLTR 587 Query: 279 YDQSPNRTGGPASGRSSKNRDGGERRPSSTSVPLGDK 315 + NRT P S K+ +GG+ P+ S P DK Sbjct: 588 WGSQGNRTPSPNSNEQQKSLNGGDEAPAPASTPQEDK 624 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 55.8 bits (133), Expect = 5e-08 Identities = 40/178 (22%), Positives = 87/178 (48%), Gaps = 9/178 (5%) Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70 +EEE + +++ +E LRE + RE E ++ Q +++ + ++L + Sbjct: 277 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKE 336 Query: 71 LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRA 130 LR + E +++ ++Q E E Q + +++Q +K R+ E+ + E+ R Sbjct: 337 LREQKELREQEEQMQEQE--------EKMWEQEEKMREQEEKMWRQEERLWEQ-EKQMRE 387 Query: 131 TIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188 + D E+R+ + ER E + E+E + E V+++++E + QE + ++EK Sbjct: 388 QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445 Score = 48.9 bits (115), Expect = 6e-06 Identities = 31/180 (17%), Positives = 91/180 (50%), Gaps = 10/180 (5%) Query: 10 SEEEEANYW-KDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSEN 68 ++E+E W ++ M ++R ++++RE +E RE E +++ Q ++++ + + + Sbjct: 571 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE 630 Query: 69 NRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128 +++ + E + E+ E + E+ + + + + +Q +K + + + + Sbjct: 631 EKMQEQEEKMWEQEEKMWEQ--------EEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQ 682 Query: 129 RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188 I E E++ Q E+ + + ++ E+E++ E +++++E +R++ Q+QE+ Sbjct: 683 EEKIWEQEKMEKK-TQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEE 741 Score = 48.5 bits (114), Expect = 8e-06 Identities = 41/191 (21%), Positives = 92/191 (48%), Gaps = 20/191 (10%) Query: 2 EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRN 61 E GK E+E W+ ++R ++ELRE ++ RE + EL Q +Q++ + Sbjct: 304 EQEGKM---REQEEKMWRQ-----EKRLREQEKELREQEKELRE-QKELREQEEQMQEQE 354 Query: 62 RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQAN 121 + + ++R + +EK Q + Q + + Q + ++DQ ++ + E+ Sbjct: 355 EKMWEQEEKMREQ----EEKMWRQEERLWEQEKQMRE---QEQKMRDQEERMWEQDERLR 407 Query: 122 DDLERAKRATIM--SLEDF--EQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLR 177 + ER + M +E E+++ + ++ E ++ E+E + E +++++E +R Sbjct: 408 EKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMR 467 Query: 178 QELAVQQKQEK 188 ++ QKQE+ Sbjct: 468 EQEEKMQKQEE 478 Score = 41.6 bits (96), Expect = 0.001 Identities = 36/195 (18%), Positives = 95/195 (48%), Gaps = 9/195 (4%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 M++ + +EE+ ++ ++R ++++RE ++ R+ E + Q +++ + Sbjct: 350 MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 409 Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120 + + E ++ ++E ++E+ ++Q E ++ E+ + + + I+++ +K E E Sbjct: 410 -EERMREQEKMWEQVEKMREEKKMQEQE--KKTRDQEEKMQEEERIREREKKMREEEETM 466 Query: 121 NDDLERAKRATIMSLEDFE-----QRLNQAIERNAFLESELDEKENLLESVQRLKDEARD 175 + E+ ++ E E QRL + E+ E +++E + E ++++D+ Sbjct: 467 REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 526 Query: 176 LRQELAVQQKQEKPR 190 QE + +QEK R Sbjct: 527 WGQEKKM-WRQEKMR 540 Score = 41.6 bits (96), Expect = 0.001 Identities = 39/184 (21%), Positives = 86/184 (46%), Gaps = 6/184 (3%) Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQI-ETRNRDLLSENN 69 E+E+ ++ M ++R ++++RE +E RE E +++ Q + + E ++ + Sbjct: 434 EQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL 493 Query: 70 RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQL-QKYIRELEQANDDLERAK 128 + E +EK + Q + + Q + D K Q+ +RE E + E Sbjct: 494 PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 553 Query: 129 RATIMSLEDFEQRLN---QAIERNAF-LESELDEKENLLESVQRLKDEARDLRQELAVQQ 184 R + D E+R+ Q E+ + E ++ E+E + E +++++E +R++ Q Sbjct: 554 RDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQ 613 Query: 185 KQEK 188 +QE+ Sbjct: 614 EQEE 617 Score = 37.7 bits (86), Expect = 0.015 Identities = 32/185 (17%), Positives = 85/185 (45%), Gaps = 6/185 (3%) Query: 10 SEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69 ++E+E W M ++ ++++RE +E RE E +++ Q ++++ + ++ + Sbjct: 696 TQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEE 755 Query: 70 RLRMELETIKEKFEVQHSE----GYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLE 125 ++ + E + E+ + + + ++ E Q + ++DQ +K + E+ E Sbjct: 756 KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEE 815 Query: 126 RAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQK 185 + + E+ Q + E ++E + E +Q +++ R+ QE ++ + Sbjct: 816 KMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMRE--QEEKMRGQ 873 Query: 186 QEKPR 190 +EK R Sbjct: 874 EEKMR 878 Score = 35.4 bits (80), Expect = 0.072 Identities = 37/187 (19%), Positives = 86/187 (45%), Gaps = 25/187 (13%) Query: 12 EEEANYWKDLAM------TYKQRAENTQEELREFQEGSREYE-AELETQLQQIETRNRDL 64 E+E W+ + ++ QE+++E +E E E E +TQ Q+ +T +++ Sbjct: 649 EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEK 708 Query: 65 LSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL 124 + E +R + ++E+ E+ + + E Q + + +Q +K + E+ + Sbjct: 709 MREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWE-- 766 Query: 125 ERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLR-QELAVQ 183 +QRL + E+ + ++ E+E + E ++++D+ +R QE ++ Sbjct: 767 --------------QQRLPEQKEK-LWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMR 811 Query: 184 QKQEKPR 190 ++EK R Sbjct: 812 GQEEKMR 818 Score = 35.0 bits (79), Expect = 0.094 Identities = 40/180 (22%), Positives = 82/180 (45%), Gaps = 16/180 (8%) Query: 13 EEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLR 72 EE +D R T EEL++ AEL+ +L E SE + ++ Sbjct: 200 EELTKERDALSLELYRNTITNEELKK-------KNAELQEKLPLAE-------SEKSEIQ 245 Query: 73 MELETIKEKFE-VQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRAT 131 + ++ +K K E + Q + L++++ + + + +K IR+ E+ E R Sbjct: 246 LNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQ 305 Query: 132 IMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLR-QELAVQQKQEKPR 190 + + E+++ + +R E EL E+E L + L+++ ++ QE + +++EK R Sbjct: 306 EGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMR 365 >gi|41872583 Rho-associated, coiled-coil containing protein kinase 2 [Homo sapiens] Length = 1388 Score = 55.1 bits (131), Expect = 9e-08 Identities = 56/222 (25%), Positives = 97/222 (43%), Gaps = 46/222 (20%) Query: 12 EEEANYWKDLAMTYKQRAENTQ---EELREFQEGS-----------------REYEAELE 51 E + N KD K+R +N+Q E++ + Q R+ +AE Sbjct: 530 ENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESS 589 Query: 52 TQLQQIETRNRDL-----LSENNRLRMELETIKEKFEVQHSEGYR------------QIS 94 Q+QQ+E+ NRDL L E +L++E E I + ++ R +I Sbjct: 590 KQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRIC 649 Query: 95 ALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR----ATIMSLEDFEQRLNQAIERNA 150 LE+DL K + +++ R+L++ DLE+ K L+ +Q L Q + Sbjct: 650 GLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHK 709 Query: 151 FLESELDEKENLLESVQRLKDEA-----RDLRQELAVQQKQE 187 ++ L +K + ES++ K EA + L +E ++QK E Sbjct: 710 ATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVE 751 Score = 43.9 bits (102), Expect = 2e-04 Identities = 46/191 (24%), Positives = 84/191 (43%), Gaps = 18/191 (9%) Query: 7 TFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQ-------IET 59 T E++ + M K E ELR+ ++ + EL+ QL+ +T Sbjct: 819 TLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKT 878 Query: 60 RNRDL---LSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRE 116 + R+L E +L EL+ K++ + + R A + ++ TKA +QL + I Sbjct: 879 QVRELKEECEEKTKLGKELQQKKQELQDE-----RDSLAAQLEITLTKADSEQLARSI-- 931 Query: 117 LEQANDDLERAKRATIMSLEDFEQRLNQAI-ERNAFLESELDEKENLLESVQRLKDEARD 175 E+ DLE+ K + +++ R Q + E++A + S + L V L +E + Sbjct: 932 AEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEE 991 Query: 176 LRQELAVQQKQ 186 L +L Q+Q Sbjct: 992 LNNKLKDVQEQ 1002 Score = 42.7 bits (99), Expect = 5e-04 Identities = 40/167 (23%), Positives = 79/167 (47%), Gaps = 29/167 (17%) Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85 +Q A+ +EL++ E + + +TQ++++ ++ E +L EL+ K++ + + Sbjct: 852 RQDADGQMKELQDQLEAEQYFSTLYKTQVREL----KEECEEKTKLGKELQQKKQELQDE 907 Query: 86 HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA------------------ 127 R A + ++ TKA +QL + I E + ++ + E+ Sbjct: 908 -----RDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELT 962 Query: 128 -KRATIMSLEDFEQRLNQAIERNAFLESELDEK-ENLLESVQRLKDE 172 K ATI SLE+ + L + A + EL+ K +++ E + RLKDE Sbjct: 963 EKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDE 1009 Score = 39.7 bits (91), Expect = 0.004 Identities = 32/120 (26%), Positives = 58/120 (48%), Gaps = 6/120 (5%) Query: 62 RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQAN 121 R+ S +R E + I++K ++ A E+ + K++ +L+K +ELE+ Sbjct: 429 RETDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEE-E 487 Query: 122 DDLERAKRATIMSLEDFE---QRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQ 178 L ++ + + LE + Q N +R A + E D+K NL V LKD+ DL++ Sbjct: 488 ITLRKSVESALRQLEREKALLQHKNAEYQRKA--DHEADKKRNLENDVNSLKDQLEDLKK 545 Score = 39.3 bits (90), Expect = 0.005 Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 11/157 (7%) Query: 35 ELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQIS 94 E++E ++ E + + +E NR L S+ L E E + K + + Q+S Sbjct: 949 EIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLK----DVQEQLS 1004 Query: 95 ALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIER-----N 149 L+D+ AIK Q +K + E+ K A IM+ ++ +R N R N Sbjct: 1005 RLKDEEISAAAIKAQFEKQLL-TERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKEN 1063 Query: 150 AFLESEL-DEKENLLESVQRLKDEARDLRQELAVQQK 185 L EL E+E L + + + + E +++ ++A + + Sbjct: 1064 RKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQ 1100 Score = 35.0 bits (79), Expect = 0.094 Identities = 39/188 (20%), Positives = 83/188 (44%), Gaps = 9/188 (4%) Query: 20 DLAMTYKQ--RAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELET 77 DL M +Q + ++++L++ E + LE Q ++ +D + L+ +LE Sbjct: 809 DLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEA 868 Query: 78 IKEKFEVQHSEGYR-QISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLE 136 E S Y+ Q+ L+++ + + +LQ+ +EL+ D L T+ + Sbjct: 869 -----EQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKAD 923 Query: 137 DFEQRLNQAIERNAFLESELDEKE-NLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPS 195 + + A E+ + LE E KE + E + R K E + +A ++ + T + Sbjct: 924 SEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVA 983 Query: 196 SVEAERTD 203 ++ E+ + Sbjct: 984 NLANEKEE 991 Score = 31.6 bits (70), Expect = 1.0 Identities = 16/62 (25%), Positives = 36/62 (58%), Gaps = 3/62 (4%) Query: 67 ENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLER 126 EN +L MEL++ +EK Q + ++++ ++ +A+ I+ +LQ L+ + D+E+ Sbjct: 1062 ENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQ---MTLDSKDSDIEQ 1118 Query: 127 AK 128 + Sbjct: 1119 LR 1120 >gi|32698688 citron [Homo sapiens] Length = 2027 Score = 55.1 bits (131), Expect = 9e-08 Identities = 50/203 (24%), Positives = 94/203 (46%), Gaps = 30/203 (14%) Query: 24 TYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFE 83 T + E +L E E + + +L ++ETR R++ E+ ++EL+ + + Sbjct: 821 TQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQ 880 Query: 84 VQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA--------------NDDLER--- 126 + E Q++AL+ A A++ QL++ ELE+ D+++R Sbjct: 881 LSLQERESQLTALQ---AARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFD 937 Query: 127 AKRATIMSLEDFEQRLNQAIERNA-------FLESELDEKENLLESVQRLKDEARDLRQE 179 A R + + D E++LNQ E NA +L +LDE + + +L+ E LR+E Sbjct: 938 ALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRRE 997 Query: 180 LAVQQKQEKPRTPMPSSVEAERT 202 + ++E T ++EA +T Sbjct: 998 IT---EREMQLTSQKQTMEALKT 1017 Score = 38.1 bits (87), Expect = 0.011 Identities = 28/135 (20%), Positives = 65/135 (48%), Gaps = 3/135 (2%) Query: 29 AENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSE 88 AE +E+ RE Q ++ E L+ + Q E + + L ++ + + ET++ + E Sbjct: 693 AEELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEE 752 Query: 89 GYRQISALEDDLAQTKAIKDQ---LQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQA 145 + + L + A A+ + L++ I EL +AN + T +++ E+ +++ Sbjct: 753 AHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISEL 812 Query: 146 IERNAFLESELDEKE 160 ++ +LE++ + E Sbjct: 813 RQQKFYLETQAGKLE 827 Score = 37.0 bits (84), Expect = 0.025 Identities = 53/214 (24%), Positives = 84/214 (39%), Gaps = 27/214 (12%) Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85 KQR Q +L++ + + + L LQ+ R L +E + L +LE I+ + + Sbjct: 1149 KQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHE 1208 Query: 86 HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQA 145 + IS QTK I + QA D K+ + S + L Sbjct: 1209 KVKMEGTIS------QQTKLI---------DFLQAKMDQPAKKKKGLFSRRKEDPALPTQ 1253 Query: 146 I-----ERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEAE 200 + E LE E L E++Q+ + E R R+E A ++ + P PS+ Sbjct: 1254 VPLQYNELKLALEKEKARCAELEEALQKTRIELRSAREEAAHRKATDHPH---PSTPATA 1310 Query: 201 RTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRR 234 R A+ A P H+ + SL P S RR Sbjct: 1311 RQQIAMSAIVRSPE----HQPSAMSLLAPPSSRR 1340 Score = 35.0 bits (79), Expect = 0.094 Identities = 46/191 (24%), Positives = 84/191 (43%), Gaps = 31/191 (16%) Query: 20 DLAMTYKQRAENTQEELREFQEGSREYEA---------ELETQLQQIETRNRDLLSENNR 70 +L T + E Q E R+++A +LE QL Q+ N +L ++N Sbjct: 910 ELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFY 969 Query: 71 LRMEL--------ETIKEKFEVQH-----SEGYRQISALEDDLAQTKAIKDQLQKYIREL 117 L +L E ++ + EV H +E Q+++ + + K L++ + +L Sbjct: 970 LSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVMDL 1029 Query: 118 EQANDDL---ERAKRATIMSLEDFEQRLNQAIERNAFLESELD-EKENLLESVQRLKDEA 173 E ND+L ER A L D + + + L+ LD EK++ + QR+ + Sbjct: 1030 EALNDELLEKERQWEAWRSVLGDEKSQFECRVRE---LQRMLDTEKQSRARADQRITESR 1086 Query: 174 RDLRQELAVQQ 184 + + ELAV++ Sbjct: 1087 QVV--ELAVKE 1095 Score = 33.5 bits (75), Expect = 0.27 Identities = 35/148 (23%), Positives = 69/148 (46%), Gaps = 20/148 (13%) Query: 53 QLQQIETRNRDLLSENNRLRMELETIKEK-FEVQHSEGYRQISALEDDLAQTKAIKDQLQ 111 ++ Q + + LL + +L+ IKE+ ++ Q E ++ LE+DL + D + Sbjct: 527 EVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYE 586 Query: 112 KYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKD 171 +RE A ++ +R +AT + + +L +A ++ + E+ E L Sbjct: 587 SELRESRLAAEEFKR--KAT-----ECQHKLLKAKDQG---KPEVGEYAKL--------- 627 Query: 172 EARDLRQELAVQQKQEKPRTPMPSSVEA 199 E + Q+L +Q+ QEK + +S EA Sbjct: 628 EKINAEQQLKIQELQEKLEKAVKASTEA 655 Score = 32.7 bits (73), Expect = 0.47 Identities = 36/184 (19%), Positives = 88/184 (47%), Gaps = 16/184 (8%) Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSR----EY------EAELETQLQQIETRN 61 E E + A +K++A Q +L + ++ + EY AE + ++Q+++ + Sbjct: 586 ESELRESRLAAEEFKRKATECQHKLLKAKDQGKPEVGEYAKLEKINAEQQLKIQELQEKL 645 Query: 62 RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQAN 121 + + L+ I++ E R++ L++ ++ I+ +L + ELE+ + Sbjct: 646 EKAVKASTEATELLQNIRQAKE----RAERELEKLQNREDSSEGIRKKLVE-AEELEEKH 700 Query: 122 DDLERAKRATIMSLEDFEQRLNQAIE-RNAFLESELDEKENLLESVQRLKDEARDLRQEL 180 + + + + + L+ EQ + I+ + ++ +L +KE L +QR ++EA + + L Sbjct: 701 REAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEEAHEKGKIL 760 Query: 181 AVQQ 184 + Q+ Sbjct: 761 SEQK 764 >gi|34878904 synaptonemal complex protein 1 [Homo sapiens] Length = 976 Score = 54.3 bits (129), Expect = 2e-07 Identities = 49/189 (25%), Positives = 89/189 (47%), Gaps = 25/189 (13%) Query: 13 EEANYWKDLAMTYKQRAENTQE---ELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69 E ++ L++ K+ + T + EL+ QE + + E L+QIE +L Sbjct: 515 ELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIE----NLQETET 570 Query: 70 RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR 129 +LR ELE ++E+ + + E ++ E++ + + KYI EL+Q N L++ Sbjct: 571 QLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGT 630 Query: 130 ATIMSLEDFEQRLNQAI-----------ERNAFLESELDEK----ENLLESVQRLK---D 171 A L +E ++N+ E + E+++K ENLLE V++ K D Sbjct: 631 AESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIAD 690 Query: 172 EARDLRQEL 180 EA L++E+ Sbjct: 691 EAVKLQKEI 699 Score = 43.1 bits (100), Expect = 3e-04 Identities = 41/208 (19%), Positives = 88/208 (42%), Gaps = 20/208 (9%) Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELE-------TQLQQIETRNRD 63 E E+ WK ++ E+ +E R+ E R+ EL+ +L++ N+D Sbjct: 112 EAEKIKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQELQFGNEKVSLKLEEGIQENKD 171 Query: 64 LLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDD 123 L+ ENN R +KE + + E+ + + ++K I E+ Sbjct: 172 LIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMITAFEELRVQ 231 Query: 124 LERAKRATIMSL-----------EDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDE 172 E ++ L +++++ +N ++ + L ++ EKEN ++ + L +E Sbjct: 232 AENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEE 291 Query: 173 ARDLRQELAVQQKQEKPRTPMPSSVEAE 200 +RD +L ++K + + S+E + Sbjct: 292 SRDKVNQL--EEKTKLQSENLKQSIEKQ 317 Score = 41.2 bits (95), Expect = 0.001 Identities = 34/171 (19%), Positives = 84/171 (49%), Gaps = 12/171 (7%) Query: 49 ELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKD 108 +L+T+L+ + +N +L S N+L +E + + + + S+ ++ ++D+ K ++ Sbjct: 501 DLKTELENEKLKNTELTSHCNKLSLENKELTQ----ETSDMTLELKNQQEDINNNKKQEE 556 Query: 109 QLQKYIRELE----QANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLE 164 ++ K I L+ Q ++LE + ++ + +L+++ E L +++ K +E Sbjct: 557 RMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIE 616 Query: 165 SVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPST 215 +Q+ E + L+++ + KQ + +E E ++A Q G + T Sbjct: 617 ELQQ---ENKALKKKGTAESKQLNVYEIKVNKLELE-LESAKQKFGEITDT 663 Score = 39.3 bits (90), Expect = 0.005 Identities = 44/166 (26%), Positives = 77/166 (46%), Gaps = 23/166 (13%) Query: 30 ENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEG 89 EN ++L E SR+ +LE + + + + + + L ELE I K +Q S Sbjct: 279 ENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDI--KVSLQRSVS 336 Query: 90 YRQISALEDDL-AQTKAIKDQLQKYIRELEQANDDLERAKRA----------TIMSLEDF 138 ++ ALE+DL TK I ++ ++E++N +A+ A T+ SLE+ Sbjct: 337 TQK--ALEEDLQIATKTICQLTEEKETQMEESN----KARAAHSFVVTEFETTVCSLEEL 390 Query: 139 EQRLNQAIERN----AFLESELDEKENLLESVQRLKDEARDLRQEL 180 + Q +E+N L EL +K + LE + +L + +EL Sbjct: 391 LRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEEL 436 Score = 37.7 bits (86), Expect = 0.015 Identities = 39/189 (20%), Positives = 84/189 (44%), Gaps = 21/189 (11%) Query: 33 QEELREFQEGSREYEAELETQLQQI----------ETRNRDLLSENNRLRMELETIKEKF 82 +E+ + Q +EY+ E+ + +Q+ E + +DL R ++ ++EK Sbjct: 244 KEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKT 303 Query: 83 EVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRL 142 ++Q + I + + IK LQ+ + + +DL+ A + E+ E ++ Sbjct: 304 KLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQM 363 Query: 143 ---NQAIERNAFLESELDE-----KENLLESVQRL---KDEARDLRQELAVQQKQEKPRT 191 N+A ++F+ +E + +E L QRL +D+ + L EL + + + T Sbjct: 364 EESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMT 423 Query: 192 PMPSSVEAE 200 + ++ E E Sbjct: 424 KLTNNKEVE 432 >gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 53.9 bits (128), Expect = 2e-07 Identities = 41/179 (22%), Positives = 80/179 (44%), Gaps = 5/179 (2%) Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85 K+R Q+ R+ +E + ++EA T + ++ D ++E L+ +K+K E + Sbjct: 1171 KKREAEFQKMRRDLEEATLQHEATAAT----LRKKHADSVAELGEQIDNLQRVKQKLEKE 1226 Query: 86 HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQA 145 SE +I L ++ K L+K R LE +L+ + + D + + Sbjct: 1227 KSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRL 1286 Query: 146 IERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQE-KPRTPMPSSVEAERTD 203 + +LDEKE L+ + R K +EL Q ++E K + + ++++ R D Sbjct: 1287 QTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHD 1345 Score = 49.7 bits (117), Expect = 4e-06 Identities = 58/242 (23%), Positives = 108/242 (44%), Gaps = 47/242 (19%) Query: 10 SEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69 +EE++ N + +Q+ ++ EGS E E +L L++ + + L Sbjct: 1018 AEEDKVNTLTKAKIKLEQQVDDL--------EGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1069 Query: 70 RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL----- 124 M++E K++ + + + +IS L+ + +A+ QLQK I+EL+ ++L Sbjct: 1070 ESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIE 1129 Query: 125 -ERAKRATI--------MSLEDFEQRLNQA-------IERNAFLESELDE-KENLLESVQ 167 ERA RA LE+ +RL +A IE N E+E + + +L E+ Sbjct: 1130 AERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATL 1189 Query: 168 RLKDEARDLRQELA---------------VQQKQEKPRTPMPSSVE--AERTDTAVQATG 210 + + A LR++ A V+QK EK ++ M ++ A +T +A G Sbjct: 1190 QHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKG 1249 Query: 211 SV 212 ++ Sbjct: 1250 NL 1251 Score = 48.5 bits (114), Expect = 8e-06 Identities = 58/240 (24%), Positives = 116/240 (48%), Gaps = 43/240 (17%) Query: 9 SSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYE---AELETQLQQIETRNRDLL 65 + +EEE N +T K+R ++E E ++ + E A++E + E + ++L Sbjct: 932 AEDEEEIN----AELTAKKR--KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 985 Query: 66 SENNRLRMELETI-KEKFEVQ--HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQAND 122 E L + + KEK +Q H + + A ED + K +L++ + +LE + + Sbjct: 986 EEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLE 1045 Query: 123 -------DLERAKR----------ATIMSLEDFEQRLNQAIERNAF----LESELDEKEN 161 DLERAKR +IM +E+ +Q+L++ +++ F L+S++++++ Sbjct: 1046 QEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQA 1105 Query: 162 LLESVQ--------RLKDEARDLRQELAVQQKQEKPRTPMPSSVE--AERTDTAVQATGS 211 L +Q R+++ ++ E A + K EK R+ + +E +ER + A AT + Sbjct: 1106 LGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA 1165 Score = 43.1 bits (100), Expect = 3e-04 Identities = 57/200 (28%), Positives = 91/200 (45%), Gaps = 46/200 (23%) Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAEL-------ETQLQQIETRNRD 63 ++++ N+ K LA +KQ+ E T EL Q+ +R EL E L Q+ET R Sbjct: 1449 DKKQRNFDKILA-EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKR- 1506 Query: 64 LLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDD 123 EN L+ E+ + E Q +EG ++I LE K +++EQ + Sbjct: 1507 ---ENKNLQQEISDLTE----QIAEGGKRIHELE--------------KIKKQVEQEKCE 1545 Query: 124 LERAKRATIMSLEDFEQR-------LNQA---IERN-AFLESELDE-KEN---LLESVQR 168 L+ A SLE E + LNQ ++R A + E+D+ K N ++ES+Q Sbjct: 1546 LQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQS 1605 Query: 169 LKD-EARDLRQELAVQQKQE 187 D E R + +++K E Sbjct: 1606 TLDAEIRSRNDAIRLKKKME 1625 Score = 42.0 bits (97), Expect = 8e-04 Identities = 30/118 (25%), Positives = 64/118 (54%), Gaps = 22/118 (18%) Query: 74 ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIM 133 E+ T+KE+F+ ++D+LA+++A + +L++ + L + +DL+ +A Sbjct: 854 EMATMKEEFQ-----------KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAE 902 Query: 134 SLEDFEQRLNQAIERNAFLESEL--------DEKE---NLLESVQRLKDEARDLRQEL 180 L D E+R +Q I+ LE+++ DE+E L ++L+DE +L++++ Sbjct: 903 GLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960 Score = 36.2 bits (82), Expect = 0.042 Identities = 53/189 (28%), Positives = 79/189 (41%), Gaps = 42/189 (22%) Query: 9 SSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQL--------QQIETR 60 S EEE+ DL QR Q E EF E EA L +QL QQIE Sbjct: 1267 SKEEEQQRLINDLTA---QRGR-LQTESGEFSRQLDEKEA-LVSQLSRGKQAFTQQIEEL 1321 Query: 61 NRDLLSE---NNRL-------RMELETIKEKFEVQH---SEGYRQISALEDDLAQTKAIK 107 R L E N L R + + ++E++E + +E R +S ++AQ + Sbjct: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRT-- 1379 Query: 108 DQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQ 167 KY + Q ++LE AK+ L+ E+ + + A LE ++ Q Sbjct: 1380 ----KYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLE----------KTKQ 1425 Query: 168 RLKDEARDL 176 RL++E DL Sbjct: 1426 RLQNEVEDL 1434 Score = 35.0 bits (79), Expect = 0.094 Identities = 46/207 (22%), Positives = 86/207 (41%), Gaps = 31/207 (14%) Query: 27 QRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLS--ENNRLRM--ELETIKEKF 82 Q + + + LRE E +E +AEL+ L + T + E + ++ ELE K+K Sbjct: 1340 QSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKL 1399 Query: 83 EVQHSEGYRQISALEDDLAQTKAIKDQLQKYIREL----EQAN---DDLERAKRATIMSL 135 + + A+ A + K +LQ + +L E+ N L++ +R L Sbjct: 1400 AQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKIL 1459 Query: 136 EDFEQRLNQAIE-------------------RNAFLESELDEKENLLESVQRLKDEARDL 176 +++Q+ + +NA+ ES LD+ E L + L+ E DL Sbjct: 1460 AEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEES-LDQLETLKRENKNLQQEISDL 1518 Query: 177 RQELAVQQKQEKPRTPMPSSVEAERTD 203 +++A K+ + VE E+ + Sbjct: 1519 TEQIAEGGKRIHELEKIKKQVEQEKCE 1545 >gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 53.9 bits (128), Expect = 2e-07 Identities = 41/179 (22%), Positives = 80/179 (44%), Gaps = 5/179 (2%) Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85 K+R Q+ R+ +E + ++EA T + ++ D ++E L+ +K+K E + Sbjct: 1171 KKREAEFQKMRRDLEEATLQHEATAAT----LRKKHADSVAELGEQIDNLQRVKQKLEKE 1226 Query: 86 HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQA 145 SE +I L ++ K L+K R LE +L+ + + D + + Sbjct: 1227 KSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRL 1286 Query: 146 IERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQE-KPRTPMPSSVEAERTD 203 + +LDEKE L+ + R K +EL Q ++E K + + ++++ R D Sbjct: 1287 QTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHD 1345 Score = 49.7 bits (117), Expect = 4e-06 Identities = 58/242 (23%), Positives = 108/242 (44%), Gaps = 47/242 (19%) Query: 10 SEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69 +EE++ N + +Q+ ++ EGS E E +L L++ + + L Sbjct: 1018 AEEDKVNTLTKAKIKLEQQVDDL--------EGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1069 Query: 70 RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL----- 124 M++E K++ + + + +IS L+ + +A+ QLQK I+EL+ ++L Sbjct: 1070 ESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIE 1129 Query: 125 -ERAKRATI--------MSLEDFEQRLNQA-------IERNAFLESELDE-KENLLESVQ 167 ERA RA LE+ +RL +A IE N E+E + + +L E+ Sbjct: 1130 AERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATL 1189 Query: 168 RLKDEARDLRQELA---------------VQQKQEKPRTPMPSSVE--AERTDTAVQATG 210 + + A LR++ A V+QK EK ++ M ++ A +T +A G Sbjct: 1190 QHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKG 1249 Query: 211 SV 212 ++ Sbjct: 1250 NL 1251 Score = 48.5 bits (114), Expect = 8e-06 Identities = 58/240 (24%), Positives = 116/240 (48%), Gaps = 43/240 (17%) Query: 9 SSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYE---AELETQLQQIETRNRDLL 65 + +EEE N +T K+R ++E E ++ + E A++E + E + ++L Sbjct: 932 AEDEEEIN----AELTAKKR--KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 985 Query: 66 SENNRLRMELETI-KEKFEVQ--HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQAND 122 E L + + KEK +Q H + + A ED + K +L++ + +LE + + Sbjct: 986 EEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLE 1045 Query: 123 -------DLERAKR----------ATIMSLEDFEQRLNQAIERNAF----LESELDEKEN 161 DLERAKR +IM +E+ +Q+L++ +++ F L+S++++++ Sbjct: 1046 QEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQA 1105 Query: 162 LLESVQ--------RLKDEARDLRQELAVQQKQEKPRTPMPSSVE--AERTDTAVQATGS 211 L +Q R+++ ++ E A + K EK R+ + +E +ER + A AT + Sbjct: 1106 LGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA 1165 Score = 43.1 bits (100), Expect = 3e-04 Identities = 57/200 (28%), Positives = 91/200 (45%), Gaps = 46/200 (23%) Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAEL-------ETQLQQIETRNRD 63 ++++ N+ K LA +KQ+ E T EL Q+ +R EL E L Q+ET R Sbjct: 1449 DKKQRNFDKILA-EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKR- 1506 Query: 64 LLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDD 123 EN L+ E+ + E Q +EG ++I LE K +++EQ + Sbjct: 1507 ---ENKNLQQEISDLTE----QIAEGGKRIHELE--------------KIKKQVEQEKCE 1545 Query: 124 LERAKRATIMSLEDFEQR-------LNQA---IERN-AFLESELDE-KEN---LLESVQR 168 L+ A SLE E + LNQ ++R A + E+D+ K N ++ES+Q Sbjct: 1546 LQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQS 1605 Query: 169 LKD-EARDLRQELAVQQKQE 187 D E R + +++K E Sbjct: 1606 TLDAEIRSRNDAIRLKKKME 1625 Score = 42.0 bits (97), Expect = 8e-04 Identities = 30/118 (25%), Positives = 64/118 (54%), Gaps = 22/118 (18%) Query: 74 ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIM 133 E+ T+KE+F+ ++D+LA+++A + +L++ + L + +DL+ +A Sbjct: 854 EMATMKEEFQ-----------KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAE 902 Query: 134 SLEDFEQRLNQAIERNAFLESEL--------DEKE---NLLESVQRLKDEARDLRQEL 180 L D E+R +Q I+ LE+++ DE+E L ++L+DE +L++++ Sbjct: 903 GLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960 Score = 36.2 bits (82), Expect = 0.042 Identities = 53/189 (28%), Positives = 79/189 (41%), Gaps = 42/189 (22%) Query: 9 SSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQL--------QQIETR 60 S EEE+ DL QR Q E EF E EA L +QL QQIE Sbjct: 1267 SKEEEQQRLINDLTA---QRGR-LQTESGEFSRQLDEKEA-LVSQLSRGKQAFTQQIEEL 1321 Query: 61 NRDLLSE---NNRL-------RMELETIKEKFEVQH---SEGYRQISALEDDLAQTKAIK 107 R L E N L R + + ++E++E + +E R +S ++AQ + Sbjct: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRT-- 1379 Query: 108 DQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQ 167 KY + Q ++LE AK+ L+ E+ + + A LE ++ Q Sbjct: 1380 ----KYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLE----------KTKQ 1425 Query: 168 RLKDEARDL 176 RL++E DL Sbjct: 1426 RLQNEVEDL 1434 Score = 35.0 bits (79), Expect = 0.094 Identities = 46/207 (22%), Positives = 86/207 (41%), Gaps = 31/207 (14%) Query: 27 QRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLS--ENNRLRM--ELETIKEKF 82 Q + + + LRE E +E +AEL+ L + T + E + ++ ELE K+K Sbjct: 1340 QSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKL 1399 Query: 83 EVQHSEGYRQISALEDDLAQTKAIKDQLQKYIREL----EQAN---DDLERAKRATIMSL 135 + + A+ A + K +LQ + +L E+ N L++ +R L Sbjct: 1400 AQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKIL 1459 Query: 136 EDFEQRLNQAIE-------------------RNAFLESELDEKENLLESVQRLKDEARDL 176 +++Q+ + +NA+ ES LD+ E L + L+ E DL Sbjct: 1460 AEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEES-LDQLETLKRENKNLQQEISDL 1518 Query: 177 RQELAVQQKQEKPRTPMPSSVEAERTD 203 +++A K+ + VE E+ + Sbjct: 1519 TEQIAEGGKRIHELEKIKKQVEQEKCE 1545 >gi|156104908 myosin heavy chain 6 [Homo sapiens] Length = 1939 Score = 53.9 bits (128), Expect = 2e-07 Identities = 48/186 (25%), Positives = 91/186 (48%), Gaps = 19/186 (10%) Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85 K+R Q+ R+ +E + ++EA + ++ D ++E L+ +K+K E + Sbjct: 1167 KKREAEFQKMRRDLEEATLQHEATAAA----LRKKHADSVAELGEQIDNLQRVKQKLEKE 1222 Query: 86 HSEGYRQISALEDDLAQTKAIKDQLQKYIRELE-QAND---DLERAKRATIMSLEDFEQR 141 SE ++ + ++ Q K L+K R LE QAN+ LE A+R SL DF + Sbjct: 1223 KSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQR----SLNDFTTQ 1278 Query: 142 LNQAIERNAFLESELDEKENLLESVQRLK----DEARDLRQELAVQQKQEKPRTPMPSSV 197 + N L +L+EKE L+ + R K + DL+++L +++ K + + ++ Sbjct: 1279 RAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQL---EEEGKAKNALAHAL 1335 Query: 198 EAERTD 203 ++ R D Sbjct: 1336 QSARHD 1341 Score = 46.6 bits (109), Expect = 3e-05 Identities = 48/182 (26%), Positives = 86/182 (47%), Gaps = 19/182 (10%) Query: 22 AMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEK 81 A+ KQR N + L E+++ E ++ELE+ ++ + + +L N LE + E Sbjct: 1443 ALDKKQR--NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL-ET 1499 Query: 82 FEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQR 141 F+ ++ +IS L + L + +L+K ++LE +L+ A SLE E + Sbjct: 1500 FKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGK 1559 Query: 142 LNQA-IERN---AFLESELDEKENLLESVQR------------LKDEARDLRQELAVQQK 185 + +A +E N A +E +L EK+ +E +R L E R + L V++K Sbjct: 1560 ILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKK 1619 Query: 186 QE 187 E Sbjct: 1620 ME 1621 Score = 39.7 bits (91), Expect = 0.004 Identities = 42/180 (23%), Positives = 74/180 (41%), Gaps = 17/180 (9%) Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85 +++ EE+ + + + L+T L ETR+R+ E R++ ++E + E+Q Sbjct: 1575 ERKLAEKDEEMEQAKRNHQRVVDSLQTSLDA-ETRSRN---EVLRVKKKMEGDLNEMEIQ 1630 Query: 86 HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL-------ERAKRATIMSLEDF 138 S R + + + +++ Q + + +ANDDL ER LE+ Sbjct: 1631 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEEL 1690 Query: 139 EQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVE 198 + Q E EL E E VQ L + L + ++K E T + S VE Sbjct: 1691 RAVVEQTERSRKLAEQELIETS---ERVQLLHSQNTSLINQ---KKKMESDLTQLQSEVE 1744 Score = 39.3 bits (90), Expect = 0.005 Identities = 28/118 (23%), Positives = 60/118 (50%), Gaps = 22/118 (18%) Query: 74 ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIM 133 E+ T+KE+F +++ L +++A + +L++ + L Q +DL+ +A Sbjct: 850 EMATMKEEF-----------GRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 898 Query: 134 SLEDFEQRLNQAIERNAFLESELDEKENLLESVQ-----------RLKDEARDLRQEL 180 +L D E+R +Q I+ LE+++ E LE + +L+DE +L++++ Sbjct: 899 NLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDI 956 Score = 38.5 bits (88), Expect = 0.009 Identities = 48/196 (24%), Positives = 96/196 (48%), Gaps = 36/196 (18%) Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEA---ELETQLQQIETRNRDLLSE 67 EE++ N + +Q+ ++ + L + ++ + E +LE L+ + DL E Sbjct: 1015 EEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDL--E 1072 Query: 68 NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRE----LEQANDD 123 N++L++E + K++F++ +Q S +ED+ + + QLQK ++E +E+ ++ Sbjct: 1073 NDKLQLEEKLKKKEFDIN-----QQNSKIEDE----QVLALQLQKKLKENQARIEELEEE 1123 Query: 124 L--ERAKRATI--------MSLEDFEQRLNQA-------IERNAFLESELDE-KENLLES 165 L ER RA + LE+ +RL +A IE N E+E + + +L E+ Sbjct: 1124 LEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEA 1183 Query: 166 VQRLKDEARDLRQELA 181 + + A LR++ A Sbjct: 1184 TLQHEATAAALRKKHA 1199 Score = 38.1 bits (87), Expect = 0.011 Identities = 51/231 (22%), Positives = 100/231 (43%), Gaps = 35/231 (15%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEEL-REFQE----------GSREYEAE 49 +ED + + EEA + T + + + EL R+ +E G Y + Sbjct: 1254 LEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQ 1313 Query: 50 LETQLQQIETRNRD---LLSENNRLRMELETIKEKFEVQ---HSEGYRQISALEDDLAQT 103 +E +Q+E + L R + + ++E++E + +E R +S ++AQ Sbjct: 1314 MEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW 1373 Query: 104 KAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESE----LDEK 159 + KY + Q ++LE AK+ L+D E+ + + + LE +E Sbjct: 1374 RT------KYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEI 1427 Query: 160 ENLLESVQR-------LKDEARDLRQELAV-QQKQEKPRTPMPSSVEAERT 202 E+L+ V+R L + R+ + LA +QK E+ ++ + SS + R+ Sbjct: 1428 EDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS 1478 Score = 38.1 bits (87), Expect = 0.011 Identities = 43/210 (20%), Positives = 93/210 (44%), Gaps = 38/210 (18%) Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQ---EGSREYEAELETQLQQIETRNRDLLSEN 68 E + ++ +A +++ ++ Q L++ Q + + +L+ + +E RN L +E Sbjct: 1628 EIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAEL 1687 Query: 69 NRLR--------------MELETIKEKFEVQHSEG---YRQISALEDDLAQTKAIKDQLQ 111 LR EL E+ ++ HS+ Q +E DL Q ++ +++ Sbjct: 1688 EELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQ---LQSEVE 1744 Query: 112 KYIRELEQANDDLERAKRATIMSLEDFE---------QRLNQAIERNAF-LESELDEKEN 161 + ++E A + ++A M E+ + +R+ + +E+ L+ LDE E Sbjct: 1745 EAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1804 Query: 162 LL-----ESVQRLKDEARDLRQELAVQQKQ 186 + + +Q+L+ R+L EL +QK+ Sbjct: 1805 IALKGGKKQLQKLEARVRELEGELEAEQKR 1834 Score = 37.7 bits (86), Expect = 0.015 Identities = 33/141 (23%), Positives = 61/141 (43%), Gaps = 17/141 (12%) Query: 38 EFQEGSREYEAELETQLQQIETRNRD----------LLSENNRLRMELETIKEKFEVQHS 87 EF + E E +L + +++E R+ L R R E+ +K+K E + Sbjct: 1566 EFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLN 1625 Query: 88 EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIE 147 E Q+S A+ + LQ +++ + DD RA +D ++ + Sbjct: 1626 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRAN-------DDLKENIAIVER 1678 Query: 148 RNAFLESELDEKENLLESVQR 168 RN L++EL+E ++E +R Sbjct: 1679 RNNLLQAELEELRAVVEQTER 1699 Score = 37.0 bits (84), Expect = 0.025 Identities = 35/177 (19%), Positives = 80/177 (45%), Gaps = 15/177 (8%) Query: 13 EEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAEL----ETQLQQIETRNRDLLSEN 68 EE +D + ++ +N ++ +++ Q E E + QLQ++E R R+L E Sbjct: 1769 EELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGE- 1827 Query: 69 NRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128 +E E + +++E + + E + + ++ +K + L+ D L+ Sbjct: 1828 ----LEAE------QKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKV 1877 Query: 129 RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQK 185 +A E+ E++ N + + ++ ELDE E + + ++ R +++ +QK Sbjct: 1878 KAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKQK 1934 Score = 34.3 bits (77), Expect = 0.16 Identities = 43/172 (25%), Positives = 78/172 (45%), Gaps = 14/172 (8%) Query: 13 EEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLS--ENNR 70 EE K+ Q A + + LRE E E +AEL+ L + + + E + Sbjct: 1322 EEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1381 Query: 71 LRM--ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128 ++ ELE K+K + + + A+ + + K +LQ E+E D+ER+ Sbjct: 1382 IQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQN---EIEDLMVDVERS- 1437 Query: 129 RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180 A +L+ ++ ++ + A + + +E ++ LES Q+ EAR L EL Sbjct: 1438 NAAAAALDKKQRNFDKIL---AEWKQKYEESQSELESSQK---EARSLSTEL 1483 Score = 33.9 bits (76), Expect = 0.21 Identities = 36/145 (24%), Positives = 62/145 (42%), Gaps = 18/145 (12%) Query: 43 SREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQ 102 S E E E+ T ++ R ++ L ++ R ELE + ++ Q+ A +D+L Sbjct: 844 SAETEKEMATMKEEFG-RIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLND 902 Query: 103 TKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENL 162 + DQL K +LE +++ +RL E NA L + +K L Sbjct: 903 AEERCDQLIKNKIQLE--------------AKVKEMNERLEDEEEMNAELTA---KKRKL 945 Query: 163 LESVQRLKDEARDLRQELAVQQKQE 187 + LK + DL LA +K++ Sbjct: 946 EDECSELKKDIDDLELTLAKVEKEK 970 Score = 30.8 bits (68), Expect = 1.8 Identities = 38/172 (22%), Positives = 75/172 (43%), Gaps = 15/172 (8%) Query: 31 NTQEELREFQEGSREYEAELET---QLQQIETRNRDLLSENNRLRMELETIKEKFEVQHS 87 N ++ R ++ + EY +LE L T+ L +EN L +LE KE Q + Sbjct: 1246 NLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEE-KEALISQLT 1304 Query: 88 EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIE 147 G L+ T+ ++D L++ + E +A + L A ++ + ++ + E Sbjct: 1305 RG---------KLSYTQQMED-LKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETE 1354 Query: 148 RNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEA 199 A L+ L K N + R K E +++ +++ ++K + + EA Sbjct: 1355 AKAELQRVL-SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEA 1405 >gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo sapiens] Length = 1937 Score = 53.5 bits (127), Expect = 3e-07 Identities = 56/189 (29%), Positives = 90/189 (47%), Gaps = 24/189 (12%) Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAEL-------ETQLQQIETRNRD 63 ++++ N+ K L+ +KQ+ E TQ EL Q+ SR EL E L Q+ET R Sbjct: 1446 DKKQRNFDKVLS-EWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRR- 1503 Query: 64 LLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDD 123 EN L+ E+ + E Q +EG +QI LE Q + K ++Q LE+A Sbjct: 1504 ---ENKNLQQEISDLTE----QIAEGGKQIHELEKIKKQVEQEKCEIQ---AALEEAEAS 1553 Query: 124 LERAKRATIMSLEDFEQRLNQAIERNAFLESELDE-KEN---LLESVQRLKD-EARDLRQ 178 LE + + + Q ++ + A + E+D+ K N ++E++Q D E R Sbjct: 1554 LEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRND 1613 Query: 179 ELAVQQKQE 187 L V++K E Sbjct: 1614 ALRVKKKME 1622 Score = 49.3 bits (116), Expect = 5e-06 Identities = 42/186 (22%), Positives = 85/186 (45%), Gaps = 19/186 (10%) Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85 K+R Q+ R+ +E + ++EA + + ++ D ++E L+ +K+K E + Sbjct: 1168 KKREAEFQKLRRDLEEATLQHEA----MVAALRKKHADSMAELGEQIDNLQRVKQKLEKE 1223 Query: 86 HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQA 145 SE + L + K L+K R LE +L+ + E+ ++ +N Sbjct: 1224 KSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKE-------EEQQRLINDL 1276 Query: 146 IERNAFLESE-------LDEKENLLESVQRLKDEARDLRQELAVQQKQE-KPRTPMPSSV 197 + A L++E LDEK+ L+ + R K + +EL Q ++E K + + ++ Sbjct: 1277 TAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHAL 1336 Query: 198 EAERTD 203 ++ R D Sbjct: 1337 QSSRHD 1342 Score = 45.1 bits (105), Expect = 9e-05 Identities = 51/203 (25%), Positives = 88/203 (43%), Gaps = 37/203 (18%) Query: 28 RAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHS 87 +A+ E+ + EGS E E +L L++ + + L M++E K++ + + Sbjct: 1025 KAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLE 1084 Query: 88 EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL------ERAKRATI--------M 133 + +IS L + +A++ QLQK I+EL+ ++L ERA RA Sbjct: 1085 KKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSR 1144 Query: 134 SLEDFEQRLNQA-------IERNAFLESELDEKENLLES--------VQRLKDEARDLRQ 178 LE+ +RL +A +E N E+E + LE V L+ + D Sbjct: 1145 ELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMA 1204 Query: 179 ELA--------VQQKQEKPRTPM 193 EL V+QK EK ++ + Sbjct: 1205 ELGEQIDNLQRVKQKLEKEKSEL 1227 Score = 39.7 bits (91), Expect = 0.004 Identities = 28/118 (23%), Positives = 60/118 (50%), Gaps = 22/118 (18%) Query: 74 ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIM 133 E+ T+KE+F+ +D+LA+++A + +L++ + L + +DL+ ++ Sbjct: 851 EMATMKEEFQ-----------KTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEAD 899 Query: 134 SLEDFEQRLNQAIERNAFLESELDE-----------KENLLESVQRLKDEARDLRQEL 180 SL D E+R Q I+ LE+++ E L ++L+DE +L++++ Sbjct: 900 SLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDI 957 Score = 38.1 bits (87), Expect = 0.011 Identities = 35/146 (23%), Positives = 71/146 (48%), Gaps = 21/146 (14%) Query: 35 ELREFQEGSREYEAELETQLQQIETRNRDLLSEN-NRLRMELETIKEKFEVQH---SEGY 90 +L ++ S + EL+ QL++ ET+ ++ L+ R + + ++E++E + +E Sbjct: 1303 QLSRSKQASTQQIEELKHQLEE-ETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQ 1361 Query: 91 RQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNA 150 R +S ++AQ + KY + Q ++LE AK+ L++ E+ + + A Sbjct: 1362 RALSKANSEVAQWRT------KYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCA 1415 Query: 151 FLESELDEKENLLESVQRLKDEARDL 176 LE ++ QRL++E DL Sbjct: 1416 SLE----------KTKQRLQNEVEDL 1431 Score = 38.1 bits (87), Expect = 0.011 Identities = 41/196 (20%), Positives = 79/196 (40%), Gaps = 25/196 (12%) Query: 33 QEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQ 92 +E+ E QEG E + L ++ ++ + ELE K+K + E Sbjct: 1347 REQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEH 1406 Query: 93 ISALEDDLAQTKAIKDQLQKYIREL----EQAN---DDLERAKRATIMSLEDFEQRL--- 142 + A+ A + K +LQ + +L E++N L++ +R L +++Q+ Sbjct: 1407 VEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEET 1466 Query: 143 ----------NQAIERNAF-----LESELDEKENLLESVQRLKDEARDLRQELAVQQKQE 187 ++++ F E LD+ E L + L+ E DL +++A KQ Sbjct: 1467 QAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQI 1526 Query: 188 KPRTPMPSSVEAERTD 203 + VE E+ + Sbjct: 1527 HELEKIKKQVEQEKCE 1542 >gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo sapiens] Length = 1935 Score = 53.1 bits (126), Expect = 3e-07 Identities = 41/182 (22%), Positives = 84/182 (46%), Gaps = 11/182 (6%) Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85 K+R Q+ R+ +E + ++EA + ++ D ++E L+ +K+K E + Sbjct: 1165 KKREAEFQKMRRDLEEATLQHEATAAA----LRKKHADSVAELGEQIDNLQRVKQKLEKE 1220 Query: 86 HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQA 145 SE ++ + ++ Q K L+K R LE ++ T S+ D + + Sbjct: 1221 KSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKL 1280 Query: 146 IERNAFLESELDEKENLLESVQRLK----DEARDLRQELAVQQKQEKPRTPMPSSVEAER 201 N L +LDEKE L+ + R K + DL+++L +++ K + + ++++ R Sbjct: 1281 QTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL---EEEVKAKNALAHALQSAR 1337 Query: 202 TD 203 D Sbjct: 1338 HD 1339 Score = 48.5 bits (114), Expect = 8e-06 Identities = 48/182 (26%), Positives = 86/182 (47%), Gaps = 19/182 (10%) Query: 22 AMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEK 81 A+ KQR N + L E+++ E ++ELE+ ++ + + +L N LE + E Sbjct: 1441 ALDKKQR--NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL-ET 1497 Query: 82 FEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQR 141 F+ ++ +IS L + L + +L+K ++LE +L+ A SLE E + Sbjct: 1498 FKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGK 1557 Query: 142 LNQA-IERN---AFLESELDEKENLLESVQR------------LKDEARDLRQELAVQQK 185 + +A +E N A +E +L EK+ +E +R L E R + L V++K Sbjct: 1558 ILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKK 1617 Query: 186 QE 187 E Sbjct: 1618 ME 1619 Score = 45.4 bits (106), Expect = 7e-05 Identities = 57/226 (25%), Positives = 103/226 (45%), Gaps = 42/226 (18%) Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAEL-------ETQLQQIET---R 60 ++++ N+ K LA +KQ+ E +Q EL Q+ +R EL E L+ +ET Sbjct: 1443 DKKQRNFDKILA-EWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRE 1501 Query: 61 NRDLLSENNRL------------------------RMELETIKEKFE--VQHSEGYRQIS 94 N++L E + L +MEL++ E+ E ++H EG +I Sbjct: 1502 NKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEG--KIL 1559 Query: 95 ALEDDLAQTKA-IKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLE 153 + + Q KA I+ +L + E+EQA + R + SL+ + N+A+ +E Sbjct: 1560 RAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKME 1619 Query: 154 SELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEA 199 +L+E E L R+ EA+ +Q ++Q + + + +V A Sbjct: 1620 GDLNEMEIQLSHANRMAAEAQ--KQVKSLQSLLKDTQIQLDDAVRA 1663 Score = 42.4 bits (98), Expect = 6e-04 Identities = 45/194 (23%), Positives = 89/194 (45%), Gaps = 30/194 (15%) Query: 10 SEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69 +EE++ N + +Q+ ++ EGS E E ++ L++ + + L Sbjct: 1012 AEEDKVNTLTKAKVKLEQQVDDL--------EGSLEQEKKVRMDLERAKRKLEGDLKLTQ 1063 Query: 70 RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL----- 124 M+LE K++ + + + +++AL + +A+ QLQK ++EL+ ++L Sbjct: 1064 ESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELE 1123 Query: 125 -ERAKRATI--------MSLEDFEQRLNQA-------IERNAFLESELDE-KENLLESVQ 167 ER RA + LE+ +RL +A IE N E+E + + +L E+ Sbjct: 1124 AERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATL 1183 Query: 168 RLKDEARDLRQELA 181 + + A LR++ A Sbjct: 1184 QHEATAAALRKKHA 1197 Score = 39.3 bits (90), Expect = 0.005 Identities = 38/169 (22%), Positives = 80/169 (47%), Gaps = 24/169 (14%) Query: 23 MTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKF 82 M YK+ E ++ L Q R + ++ + + LL R + E+ ++KE+F Sbjct: 799 MEYKKLLER-RDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREK-EMASMKEEF 856 Query: 83 EVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRL 142 + L++ L +++A + +L++ + L Q +DL+ +A +L D E+R Sbjct: 857 -----------TRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERC 905 Query: 143 NQAIERNAFLESELDEKENLLESVQ-----------RLKDEARDLRQEL 180 +Q I+ LE+++ E LE + +L+DE +L++++ Sbjct: 906 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI 954 Score = 39.3 bits (90), Expect = 0.005 Identities = 39/161 (24%), Positives = 69/161 (42%), Gaps = 11/161 (6%) Query: 11 EEEEANYWKDLAMTYKQRAENTQ---EELREFQEGSREYEAELETQLQQIETRNRDLLSE 67 EE EA+ + + + E Q E R+ E E E L+ +++ L +E Sbjct: 1545 EEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAE 1604 Query: 68 NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127 R R E +K+K E +E Q+S A+ + LQ +++ + DD RA Sbjct: 1605 T-RSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1663 Query: 128 KRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQR 168 +D ++ + RN L++EL+E ++E +R Sbjct: 1664 N-------DDLKENIAIVERRNNLLQAELEELRAVVEQTER 1697 Score = 38.1 bits (87), Expect = 0.011 Identities = 37/158 (23%), Positives = 76/158 (48%), Gaps = 16/158 (10%) Query: 34 EELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQI 93 EELR E + E +L + R + L S+N L + K+K + S+ ++ Sbjct: 1686 EELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQ----KKKMDADLSQLQTEV 1741 Query: 94 SALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLE 153 E+ + + + +++ +K I + ++L++ ++ T LE ++ + Q I+ L+ Sbjct: 1742 ---EEAVQECRNAEEKAKKAITDAAMMAEELKK-EQDTSAHLERMKKNMEQTIKD---LQ 1794 Query: 154 SELDEKENLL-----ESVQRLKDEARDLRQELAVQQKQ 186 LDE E + + +Q+L+ R+L EL +QK+ Sbjct: 1795 HRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKR 1832 Score = 35.4 bits (80), Expect = 0.072 Identities = 46/173 (26%), Positives = 79/173 (45%), Gaps = 15/173 (8%) Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLS--ENN 69 EEE LA Q A + + LRE E E +AEL+ L + + + E + Sbjct: 1320 EEEVKAKNALAHAL-QSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD 1378 Query: 70 RLRM--ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127 ++ ELE K+K + E + A+ + + K +LQ E+E D+ER+ Sbjct: 1379 AIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQN---EIEDLMVDVERS 1435 Query: 128 KRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180 A +L+ ++ ++ + A + + +E ++ LES Q+ EAR L EL Sbjct: 1436 -NAAAAALDKKQRNFDKIL---AEWKQKYEESQSELESSQK---EARSLSTEL 1481 Score = 33.1 bits (74), Expect = 0.36 Identities = 39/191 (20%), Positives = 82/191 (42%), Gaps = 35/191 (18%) Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85 +++ EE+ + + L+T L ETR+R+ E R++ ++E + E+Q Sbjct: 1573 ERKLAEKDEEMEQAKRNHLRVVDSLQTSLDA-ETRSRN---EALRVKKKMEGDLNEMEIQ 1628 Query: 86 HS-------EGYRQISALE-----------------DDLAQTKAIKDQ----LQKYIREL 117 S E +Q+ +L+ DDL + AI ++ LQ + EL Sbjct: 1629 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEEL 1688 Query: 118 EQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLR 177 + ER+++ L + +R+ +N L +++K+ + + +L+ E + Sbjct: 1689 RAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL---INQKKKMDADLSQLQTEVEEAV 1745 Query: 178 QELAVQQKQEK 188 QE +++ K Sbjct: 1746 QECRNAEEKAK 1756 >gi|239745153 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 53.1 bits (126), Expect = 3e-07 Identities = 39/190 (20%), Positives = 92/190 (48%), Gaps = 13/190 (6%) Query: 12 EEEANYWKDLAMTYKQRAE---------NTQEELREFQEGSREYEAELETQLQQIETRNR 62 E+E W+ ++Q + +E++RE +E RE E ++ Q ++I ++ Sbjct: 322 EQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDE 381 Query: 63 DLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQL---QKYIRELEQ 119 + + + + E I+E+ E + + +RQ + + + + ++++ ++ IRELE+ Sbjct: 382 KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEE 441 Query: 120 ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQR-LKDEARDLRQ 178 D E R +++ E+++ + E+ E ++ E+E ++ LK E + Q Sbjct: 442 MMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501 Query: 179 ELAVQQKQEK 188 E + +++EK Sbjct: 502 EEKMWRQEEK 511 Score = 48.5 bits (114), Expect = 8e-06 Identities = 38/183 (20%), Positives = 90/183 (49%), Gaps = 13/183 (7%) Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQI----ETRNRDLLS 66 +EE+ ++ +++ +E++RE E +E E E+ Q ++I E R + Sbjct: 351 QEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWR 410 Query: 67 ENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLER 126 + ++R + E I+E Q E +RQ E+ + + + + ++ +RE+E+ + E Sbjct: 411 QEKKMREQDEKIRE----QEEEMWRQ----EEKIRELEEMMQDQEEKLREVEEKMQEEEE 462 Query: 127 AKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRL-KDEARDLRQELAVQQK 185 + ++ E+++ + E+ E L ++E + E +++ + E + QE +Q++ Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQ 522 Query: 186 QEK 188 +EK Sbjct: 523 EEK 525 Score = 40.4 bits (93), Expect = 0.002 Identities = 40/218 (18%), Positives = 97/218 (44%), Gaps = 23/218 (10%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 M + + +EEE ++ ++ ++ +E+LRE +E +E E +++ Q ++I+ + Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474 Query: 61 NRDLLSENNRLRMELETIK--EKFEVQHSEGYRQISAL---EDDLAQTKAIKDQLQKYIR 115 + + + + + +K EK Q + +RQ + E+ + + + + ++ +R Sbjct: 475 EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMR 534 Query: 116 ELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLES-----------------ELDE 158 E E E + + L++ E+RL + ++ L +++ Sbjct: 535 EQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVEL 594 Query: 159 KENLLESVQRLKDEAR-DLRQELAVQQKQEKPRTPMPS 195 K +S+Q+ +D R L+Q +A Q+ + +PS Sbjct: 595 KSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEALPS 632 Score = 39.7 bits (91), Expect = 0.004 Identities = 34/201 (16%), Positives = 93/201 (46%), Gaps = 13/201 (6%) Query: 10 SEEEEANYWKDLAMTYKQRAENTQEEL--REFQEGSREYEAELETQLQQIETRNRDLLSE 67 ++++E W+ +Q + ++EL RE +E E ++ Q ++I + + + Sbjct: 292 NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQ 351 Query: 68 NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127 ++R + E I+E Q + +RQ + + Q + I++Q ++ R+ E+ + E+ Sbjct: 352 EEKIREQEEKIRE----QEEKMWRQEEKIRE---QDEKIQEQEEEMWRQEEKIREQEEKR 404 Query: 128 KRATIMS---LEDFEQRLNQAIERNAFLESELDEKENLL-ESVQRLKDEARDLRQELAVQ 183 + + + ++++ + E E ++ E E ++ + ++L++ +++E Sbjct: 405 QEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKM 464 Query: 184 QKQEKPRTPMPSSVEAERTDT 204 Q+QE+ ++ + T Sbjct: 465 QEQEEKIQRQEEKIQEQEEKT 485 Score = 32.0 bits (71), Expect = 0.80 Identities = 51/195 (26%), Positives = 91/195 (46%), Gaps = 31/195 (15%) Query: 1 MEDSGKTFSSEEEEANYWKDLA-MTYKQRAENTQ-EELREFQEGSREYEAELETQLQQIE 58 M + TF W L +T ++R EN+ EE F R + T ++++ Sbjct: 142 MNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVR-----MGTYIEKL- 195 Query: 59 TRNRDLLS-ENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIREL 117 T+ RD S E R + E +KEK + L++ L ++ K ++Q +++L Sbjct: 196 TKERDAPSLELYRNTITDEELKEKN-----------AELQEKLRLVESEKSEIQLNVKDL 244 Query: 118 EQANDDLERAKRATIMSLEDFE-QRLNQAIER-NAFLESELDEKE--NLLESVQRLKDEA 173 ++ LERA+ E RL + ++ +A L+++++E E NLL Q E Sbjct: 245 KRK---LERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQ----EE 297 Query: 174 RDLRQELAVQQKQEK 188 + RQE +Q+++EK Sbjct: 298 KMWRQEEKIQEQEEK 312 >gi|239745127 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 53.1 bits (126), Expect = 3e-07 Identities = 39/190 (20%), Positives = 92/190 (48%), Gaps = 13/190 (6%) Query: 12 EEEANYWKDLAMTYKQRAE---------NTQEELREFQEGSREYEAELETQLQQIETRNR 62 E+E W+ ++Q + +E++RE +E RE E ++ Q ++I ++ Sbjct: 322 EQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDE 381 Query: 63 DLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQL---QKYIRELEQ 119 + + + + E I+E+ E + + +RQ + + + + ++++ ++ IRELE+ Sbjct: 382 KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEE 441 Query: 120 ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQR-LKDEARDLRQ 178 D E R +++ E+++ + E+ E ++ E+E ++ LK E + Q Sbjct: 442 MMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501 Query: 179 ELAVQQKQEK 188 E + +++EK Sbjct: 502 EEKMWRQEEK 511 Score = 48.5 bits (114), Expect = 8e-06 Identities = 38/183 (20%), Positives = 90/183 (49%), Gaps = 13/183 (7%) Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQI----ETRNRDLLS 66 +EE+ ++ +++ +E++RE E +E E E+ Q ++I E R + Sbjct: 351 QEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWR 410 Query: 67 ENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLER 126 + ++R + E I+E Q E +RQ E+ + + + + ++ +RE+E+ + E Sbjct: 411 QEKKMREQDEKIRE----QEEEMWRQ----EEKIRELEEMMQDQEEKLREVEEKMQEEEE 462 Query: 127 AKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRL-KDEARDLRQELAVQQK 185 + ++ E+++ + E+ E L ++E + E +++ + E + QE +Q++ Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQ 522 Query: 186 QEK 188 +EK Sbjct: 523 EEK 525 Score = 40.4 bits (93), Expect = 0.002 Identities = 40/218 (18%), Positives = 97/218 (44%), Gaps = 23/218 (10%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 M + + +EEE ++ ++ ++ +E+LRE +E +E E +++ Q ++I+ + Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474 Query: 61 NRDLLSENNRLRMELETIK--EKFEVQHSEGYRQISAL---EDDLAQTKAIKDQLQKYIR 115 + + + + + +K EK Q + +RQ + E+ + + + + ++ +R Sbjct: 475 EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMR 534 Query: 116 ELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLES-----------------ELDE 158 E E E + + L++ E+RL + ++ L +++ Sbjct: 535 EQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVEL 594 Query: 159 KENLLESVQRLKDEAR-DLRQELAVQQKQEKPRTPMPS 195 K +S+Q+ +D R L+Q +A Q+ + +PS Sbjct: 595 KSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEALPS 632 Score = 39.7 bits (91), Expect = 0.004 Identities = 34/201 (16%), Positives = 93/201 (46%), Gaps = 13/201 (6%) Query: 10 SEEEEANYWKDLAMTYKQRAENTQEEL--REFQEGSREYEAELETQLQQIETRNRDLLSE 67 ++++E W+ +Q + ++EL RE +E E ++ Q ++I + + + Sbjct: 292 NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQ 351 Query: 68 NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127 ++R + E I+E Q + +RQ + + Q + I++Q ++ R+ E+ + E+ Sbjct: 352 EEKIREQEEKIRE----QEEKMWRQEEKIRE---QDEKIQEQEEEMWRQEEKIREQEEKR 404 Query: 128 KRATIMS---LEDFEQRLNQAIERNAFLESELDEKENLL-ESVQRLKDEARDLRQELAVQ 183 + + + ++++ + E E ++ E E ++ + ++L++ +++E Sbjct: 405 QEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKM 464 Query: 184 QKQEKPRTPMPSSVEAERTDT 204 Q+QE+ ++ + T Sbjct: 465 QEQEEKIQRQEEKIQEQEEKT 485 Score = 34.7 bits (78), Expect = 0.12 Identities = 52/195 (26%), Positives = 92/195 (47%), Gaps = 31/195 (15%) Query: 1 MEDSGKTFSSEEEEANYWKDLA-MTYKQRAENTQ-EELREFQEGSREYEAELETQLQQIE 58 M + TF W L +T ++R EN+ EE F R + T ++++ Sbjct: 142 MNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVR-----MGTYIEKL- 195 Query: 59 TRNRDLLS-ENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIREL 117 T+ RD LS E R + E +KEK + L++ L ++ K ++Q +++L Sbjct: 196 TKERDALSLELYRNTITDEELKEKN-----------AELQEKLRLVESEKSEIQLNVKDL 244 Query: 118 EQANDDLERAKRATIMSLEDFE-QRLNQAIER-NAFLESELDEKE--NLLESVQRLKDEA 173 ++ LERA+ E RL + ++ +A L+++++E E NLL Q E Sbjct: 245 KRK---LERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQ----EE 297 Query: 174 RDLRQELAVQQKQEK 188 + RQE +Q+++EK Sbjct: 298 KMWRQEEKIQEQEEK 312 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 53.1 bits (126), Expect = 3e-07 Identities = 43/184 (23%), Positives = 88/184 (47%), Gaps = 8/184 (4%) Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDL------ 64 +EEE + +++ +E LRE + RE E ++ Q +++ + ++L Sbjct: 239 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKE 298 Query: 65 LSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL 124 L E +LR + E ++E+ E + + E Q + + +Q +K +RE EQ D Sbjct: 299 LREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ-EKQMREQEQKMRDQ 357 Query: 125 ERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQ 184 E L + E+R+ + E+ E ++ E+E + E +++++E +R++ Q Sbjct: 358 EERMWEQDERLREKEERMREQ-EKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQ 416 Query: 185 KQEK 188 KQE+ Sbjct: 417 KQEE 420 Score = 45.8 bits (107), Expect = 5e-05 Identities = 38/181 (20%), Positives = 83/181 (45%), Gaps = 2/181 (1%) Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQI-ETRNRDLLSENNR 70 E+E + ++ M ++R ++++RE +E RE E +++ Q + + E ++ + Sbjct: 377 EQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 436 Query: 71 LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQL-QKYIRELEQANDDLERAKR 129 + E +EK + Q + + Q + D K Q+ +RE E + E R Sbjct: 437 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 496 Query: 130 ATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKP 189 + D E+R+ + ER E + E++ + + +++++E + QE ++EK Sbjct: 497 DQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKM 556 Query: 190 R 190 R Sbjct: 557 R 557 Score = 43.1 bits (100), Expect = 3e-04 Identities = 41/192 (21%), Positives = 95/192 (49%), Gaps = 15/192 (7%) Query: 26 KQRAENTQEELREFQEGSREYEA--ELETQLQQ---IETRNRDLLSENNRLRMELETIKE 80 ++R E LRE +E RE E E E ++Q+ I R + + E +R + E +++ Sbjct: 358 EERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQK 417 Query: 81 K----FEVQHSEGYRQ-ISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIM-- 133 + +E + E +Q + ++ L + + +++Q +K + E+ D E + M Sbjct: 418 QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR 477 Query: 134 --SLEDFEQRLNQAIERNAFLESEL-DEKENLLESVQRLKDEARDLRQELAVQQKQEKPR 190 + + E ++ + E+ E ++ D++E + E +RL+++ +R++ + Q++EK R Sbjct: 478 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMR 537 Query: 191 TPMPSSVEAERT 202 + + ++T Sbjct: 538 EEKKTQEQEKKT 549 Score = 38.9 bits (89), Expect = 0.007 Identities = 34/182 (18%), Positives = 86/182 (47%), Gaps = 8/182 (4%) Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70 +E+E W+ Q QE+ QE RE E ++ Q +++ + + + + R Sbjct: 449 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 508 Query: 71 LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRA 130 + + E ++EK E + +++ E+ + + K ++Q +K + E+ ++ +R Sbjct: 509 MWEQDERLREKEERMREQ--KKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRERE 566 Query: 131 TIMSLEDFEQRLNQAIERNAFLESELDEKENLL----ESVQRLKDEARDLRQELAVQQKQ 186 M E E+ + + E+ E ++ E+E + E +Q +++ + +++ Q+++ Sbjct: 567 KKMREE--EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEE 624 Query: 187 EK 188 +K Sbjct: 625 DK 626 Score = 38.9 bits (89), Expect = 0.007 Identities = 35/215 (16%), Positives = 99/215 (46%), Gaps = 20/215 (9%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 M + KT E+E+ + ++ M ++R ++++RE +E RE E +++ Q +++ + Sbjct: 536 MREEKKT--QEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQ 593 Query: 61 NRDLLSENNRLRMELETI------------KEKFEVQHSEGYRQISALEDD----LAQTK 104 + + +++ + E + ++K + Q + Q +++ Q + Sbjct: 594 EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEE 653 Query: 105 AIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESEL-DEKENLL 163 +++Q +K +RE E+ E R ++ E+++ + E+ E ++ ++E + Sbjct: 654 KMREQEEK-MREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMW 712 Query: 164 ESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVE 198 +++ + +E ++ ++EK + +P E Sbjct: 713 GQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEE 747 Score = 38.1 bits (87), Expect = 0.011 Identities = 40/180 (22%), Positives = 84/180 (46%), Gaps = 16/180 (8%) Query: 13 EEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLR 72 EE +D R T EEL++ AEL+ +L+ E SE + ++ Sbjct: 162 EELTKERDALSLELYRNTITNEELKK-------KNAELQEKLRLAE-------SEKSEIQ 207 Query: 73 MELETIKEKFE-VQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRAT 131 + ++ +K K E + Q + L++++ + + + +K IR+ E+ E R Sbjct: 208 LNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQ 267 Query: 132 IMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLR-QELAVQQKQEKPR 190 + + E+++ + +R E EL E+E L ++L+++ ++ QE + +++EK R Sbjct: 268 EGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMR 327 Score = 30.4 bits (67), Expect = 2.3 Identities = 39/191 (20%), Positives = 75/191 (39%), Gaps = 28/191 (14%) Query: 24 TYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRM------ELET 77 T K++ N EG E E + Q E R++ ++++ +R+ ELET Sbjct: 47 TKKKKINNGTNPETTTSEGCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELET 106 Query: 78 I-------KEKFE-------------VQHSEGYRQISALEDDLAQTKAIKDQLQKYIREL 117 KFE + HS + L+ L+ + +YI EL Sbjct: 107 ALYYSQDAARKFEDGNLGESKDLAGRLHHS--WHFAGELQRALSAVSTWHKKADRYIEEL 164 Query: 118 EQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLR 177 + D L ++ E+ +++ + E+ ESE E + ++ ++R + A+ L Sbjct: 165 TKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLL 224 Query: 178 QELAVQQKQEK 188 ++ QE+ Sbjct: 225 PQVQTNTLQEE 235 >gi|102467235 inner centromere protein antigens 135/155kDa isoform 1 [Homo sapiens] Length = 918 Score = 53.1 bits (126), Expect = 3e-07 Identities = 41/170 (24%), Positives = 79/170 (46%), Gaps = 11/170 (6%) Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85 +QR EN + + Q ++ E + +L++++ + + L + + R +E +KE+ + Q Sbjct: 539 RQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQ 598 Query: 86 HSEGYRQIS-----ALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQ 140 + + QI A E+ LA+ KA K K + E+E E A+R + E+ E+ Sbjct: 599 IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER 658 Query: 141 RLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPR 190 R L+ + +E++ L K A QE Q+++E+ R Sbjct: 659 R------HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER 702 Score = 42.7 bits (99), Expect = 5e-04 Identities = 58/233 (24%), Positives = 92/233 (39%), Gaps = 26/233 (11%) Query: 24 TYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFE 83 T K + E EE + + +++ E + Q+ E R L + R E +++K E Sbjct: 610 TEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE 669 Query: 84 VQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLN 143 + E R+ A+ K + +Q ++ RE E+ + +R E Q Sbjct: 670 -EEQERLRKA-------AEAKRLAEQREQERREQERREQERREQERREQERREQERQLAE 721 Query: 144 QAIERNAF---LESELDEKENLL----ESVQRLKDEAR--DLRQELAVQQKQEKPRTPMP 194 Q R E EL E+E L E +QR +E + + +Q LA +Q QE+ Sbjct: 722 QERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 781 Query: 195 SSVEAERT-----DTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGL--DDST 240 + A + D A S TP HR P P ++ L DDST Sbjct: 782 EAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKI--NPDNYGMDLNSDDST 832 Score = 38.9 bits (89), Expect = 0.007 Identities = 36/157 (22%), Positives = 71/157 (45%), Gaps = 5/157 (3%) Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70 EEEE + + L +++ E QE LR+ E R E + E + ++ E R ++ + R Sbjct: 654 EEEERRHQELL----QKKKEEEQERLRKAAEAKRLAE-QREQERREQERREQERREQERR 708 Query: 71 LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRA 130 + E ++ E + ++ A + + KA++ Q ++ RELE+ E+ + A Sbjct: 709 EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLA 768 Query: 131 TIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQ 167 E+ E++ +A + L +D + S Q Sbjct: 769 ERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQ 805 >gi|102467242 inner centromere protein antigens 135/155kDa isoform 2 [Homo sapiens] Length = 914 Score = 53.1 bits (126), Expect = 3e-07 Identities = 41/170 (24%), Positives = 79/170 (46%), Gaps = 11/170 (6%) Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85 +QR EN + + Q ++ E + +L++++ + + L + + R +E +KE+ + Q Sbjct: 535 RQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQ 594 Query: 86 HSEGYRQIS-----ALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQ 140 + + QI A E+ LA+ KA K K + E+E E A+R + E+ E+ Sbjct: 595 IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER 654 Query: 141 RLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPR 190 R L+ + +E++ L K A QE Q+++E+ R Sbjct: 655 R------HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER 698 Score = 42.7 bits (99), Expect = 5e-04 Identities = 58/233 (24%), Positives = 92/233 (39%), Gaps = 26/233 (11%) Query: 24 TYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFE 83 T K + E EE + + +++ E + Q+ E R L + R E +++K E Sbjct: 606 TEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE 665 Query: 84 VQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLN 143 + E R+ A+ K + +Q ++ RE E+ + +R E Q Sbjct: 666 -EEQERLRKA-------AEAKRLAEQREQERREQERREQERREQERREQERREQERQLAE 717 Query: 144 QAIERNAF---LESELDEKENLL----ESVQRLKDEAR--DLRQELAVQQKQEKPRTPMP 194 Q R E EL E+E L E +QR +E + + +Q LA +Q QE+ Sbjct: 718 QERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 777 Query: 195 SSVEAERT-----DTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGL--DDST 240 + A + D A S TP HR P P ++ L DDST Sbjct: 778 EAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKI--NPDNYGMDLNSDDST 828 Score = 38.9 bits (89), Expect = 0.007 Identities = 36/157 (22%), Positives = 71/157 (45%), Gaps = 5/157 (3%) Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70 EEEE + + L +++ E QE LR+ E R E + E + ++ E R ++ + R Sbjct: 650 EEEERRHQELL----QKKKEEEQERLRKAAEAKRLAE-QREQERREQERREQERREQERR 704 Query: 71 LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRA 130 + E ++ E + ++ A + + KA++ Q ++ RELE+ E+ + A Sbjct: 705 EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLA 764 Query: 131 TIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQ 167 E+ E++ +A + L +D + S Q Sbjct: 765 ERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQ 801 >gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo sapiens] Length = 1972 Score = 52.8 bits (125), Expect = 4e-07 Identities = 46/196 (23%), Positives = 86/196 (43%), Gaps = 6/196 (3%) Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL 71 +EE + +Q+ EEL E E + +A L+ Q +E N DL E L Sbjct: 1184 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1243 Query: 72 ---RMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128 + E+E K+K E Q E + S E A+ + D++ K E+E L A+ Sbjct: 1244 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVTGMLNEAE 1300 Query: 129 RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188 I +D +Q + L+ E +K N+ +++L++E L+ +L + + ++ Sbjct: 1301 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1360 Query: 189 PRTPMPSSVEAERTDT 204 S++ + +D+ Sbjct: 1361 NLERHISTLNIQLSDS 1376 Score = 49.3 bits (116), Expect = 5e-06 Identities = 44/199 (22%), Positives = 92/199 (46%), Gaps = 22/199 (11%) Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70 +EEE +D K+R + + EL+E ++ + E +Q++ +L +E Sbjct: 850 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEE 908 Query: 71 LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR- 129 +R+ L K++ E E ++ ED Q +A + ++ + + +LE+ ++ E A++ Sbjct: 909 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 968 Query: 130 ---------ATIMSLED----FEQRLNQAIERNAFLE-------SELDEKENLLESVQRL 169 A I LED + + N+ + LE + L E+E +++ +L Sbjct: 969 LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKL 1028 Query: 170 KDEARDLRQELAVQQKQEK 188 K++ + EL V+ K+E+ Sbjct: 1029 KNKHESMISELEVRLKKEE 1047 Score = 44.3 bits (103), Expect = 2e-04 Identities = 48/179 (26%), Positives = 83/179 (46%), Gaps = 26/179 (14%) Query: 11 EEEEANY--WKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSEN 68 EEE+ N D Q+AE EL R + E+ QQ+E +N++L S+ Sbjct: 1746 EEEQGNMEAMSDRVRKATQQAEQLSNELAT----ERSTAQKNESARQQLERQNKELRSKL 1801 Query: 69 NRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL---E 125 + + +K KF+ I+ALE +AQ +++Q+++ RE + A L + Sbjct: 1802 HEME---GAVKSKFK-------STIAALEAKIAQ---LEEQVEQEAREKQAATKSLKQKD 1848 Query: 126 RAKRATIMSLED----FEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180 + + ++ +ED EQ QA + NA ++ + E E QR+ R L++EL Sbjct: 1849 KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1907 Score = 43.9 bits (102), Expect = 2e-04 Identities = 48/213 (22%), Positives = 90/213 (42%), Gaps = 26/213 (12%) Query: 2 EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEEL------REFQEGSREYEAELETQLQ 55 E GK ++ A+ L T + E T+++L R+ +E + +L+ +++ Sbjct: 1298 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME 1357 Query: 56 QIETRNRDL------LSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQ 109 + R + LS++ + + + E E ++I L + A D+ Sbjct: 1358 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1417 Query: 110 LQKYIRELEQANDDLE---RAKRATIMSLEDFEQRLNQ--AIERNAF---------LESE 155 L+K L+Q DDL +R + +LE +++ +Q A E+N E+E Sbjct: 1418 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1477 Query: 156 LDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188 EKE S+ R +EA + ++EL K K Sbjct: 1478 AREKETKALSLARALEEALEAKEELERTNKMLK 1510 Score = 43.1 bits (100), Expect = 3e-04 Identities = 51/204 (25%), Positives = 91/204 (44%), Gaps = 29/204 (14%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 + D + EEE+A L ++ + L++ +E SR+ ELE +++E Sbjct: 1008 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK-EEKSRQ---ELEKLKRKLEGD 1063 Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120 D + L+ ++ +K + + E ++ L+D++AQ K+ K IRELE Sbjct: 1064 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ----KNNALKKIRELEGH 1119 Query: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180 DL+ ED + ER A ++E +K +L E ++ LK E D Sbjct: 1120 ISDLQ----------EDLDS------ERAARNKAE-KQKRDLGEELEALKTELEDTLDST 1162 Query: 181 AVQQ----KQEKPRTPMPSSVEAE 200 A QQ K+E+ T + +++ E Sbjct: 1163 ATQQELRAKREQEVTVLKKALDEE 1186 Score = 42.4 bits (98), Expect = 6e-04 Identities = 38/175 (21%), Positives = 73/175 (41%), Gaps = 11/175 (6%) Query: 21 LAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELET--- 77 LA ++R + + FQ R Y A +Q + ++ N ++L Sbjct: 775 LAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQW 834 Query: 78 ------IKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRAT 131 +K +V E ++ A ED+L +TK + + + ++ELEQ + L K Sbjct: 835 WRLFTKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLL 892 Query: 132 IMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186 L+ + +A E L ++ E E +L ++ +E D Q+L ++K+ Sbjct: 893 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 947 Score = 42.4 bits (98), Expect = 6e-04 Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 29/208 (13%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 +E + K +E E+ KD E ++ L E + ELE +LQ E Sbjct: 1502 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE-- 1559 Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120 RL + ++ +K +FE R + A ++ Q + + QLQ+ + E E Sbjct: 1560 -----DAKLRLEVNMQALKGQFE-------RDLQARDE---QNEEKRRQLQRQLHEYETE 1604 Query: 121 NDDLERAKRATIMS--------LEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDE 172 +D ER +RA + L+D E + + AI+ +L + + ++ QR ++ Sbjct: 1605 LED-ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1663 Query: 173 ARDLRQELAVQQKQEKPRTPMPSSVEAE 200 AR R E+ K+ + + S+EA+ Sbjct: 1664 ARASRDEIFATAKENEKKA---KSLEAD 1688 Score = 42.0 bits (97), Expect = 8e-04 Identities = 49/224 (21%), Positives = 94/224 (41%), Gaps = 24/224 (10%) Query: 4 SGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRN-- 61 +G +E + KD+A Q ++TQE L QE +R+ + + T+L+Q+E Sbjct: 1293 TGMLNEAEGKAIKLAKDVASLSSQ-LQDTQELL---QEETRQ-KLNVSTKLRQLEEERNS 1347 Query: 62 -RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ- 119 +D L E + LE +Q S+ +++ + + K + QK I L Q Sbjct: 1348 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1407 Query: 120 ------ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEA 173 A D LE+ K L+D L+ + + LE + + + LL + + + Sbjct: 1408 YEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKY 1467 Query: 174 RDLRQELAVQQKQEKPRT---------PMPSSVEAERTDTAVQA 208 D R + ++++ + + + E ERT+ ++A Sbjct: 1468 ADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKA 1511 Score = 41.6 bits (96), Expect = 0.001 Identities = 36/174 (20%), Positives = 78/174 (44%), Gaps = 18/174 (10%) Query: 29 AENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMEL----------ETI 78 AE + L ++ E E+E +L++ E R + L +E ++ ++ E Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 965 Query: 79 KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL------ERAKRATI 132 ++K +++ +I LED++ ++L K + LE+ DL E K + Sbjct: 966 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025 Query: 133 MSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186 L++ + + +E L+ E ++ L + ++L+ +A D +++A Q Q Sbjct: 1026 TKLKNKHESMISELE--VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1077 Score = 40.0 bits (92), Expect = 0.003 Identities = 41/203 (20%), Positives = 90/203 (44%), Gaps = 14/203 (6%) Query: 1 MEDS-GKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIET 59 +ED+ T + +E A +++ + K E T+ + QE +++ +E +Q+E Sbjct: 1155 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE- 1213 Query: 60 RNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ 119 + R + L+ K+ E ++++ ++ L + + K +L+ ++EL+ Sbjct: 1214 -------QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS 1266 Query: 120 ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKE-NLLESVQRLKDEARDLRQ 178 D ERA+ L D +L +E + +E + K L + V L + +D ++ Sbjct: 1267 KCSDGERAR----AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1322 Query: 179 ELAVQQKQEKPRTPMPSSVEAER 201 L + +Q+ + +E ER Sbjct: 1323 LLQEETRQKLNVSTKLRQLEEER 1345 Score = 36.6 bits (83), Expect = 0.032 Identities = 47/233 (20%), Positives = 87/233 (37%), Gaps = 20/233 (8%) Query: 19 KDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETI 78 + L +++ + L E + S +Y E + + + LS L LE Sbjct: 1440 RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA- 1498 Query: 79 KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDF 138 KE+ E + + + A +DL +K D + K + ELE++ LE LE+ Sbjct: 1499 KEELERTN----KMLKAEMEDLVSSK---DDVGKNVHELEKSKRALETQMEEMKTQLEEL 1551 Query: 139 EQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQ------------ELAVQQKQ 186 E L + LE + + E + +DE + ++ EL ++KQ Sbjct: 1552 EDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ 1611 Query: 187 EKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDS 239 +E + D +QA ++ A + F+R L+D+ Sbjct: 1612 RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1664 Score = 36.2 bits (82), Expect = 0.042 Identities = 41/195 (21%), Positives = 86/195 (44%), Gaps = 22/195 (11%) Query: 31 NTQEELREFQEGSREYEAELETQL---QQIETRNRDLLSENNRLRMELETIKEKFEVQH- 86 N +++RE + + + +L+++ + E + RDL E L+ ELE + Q Sbjct: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167 Query: 87 --SEGYRQISAL-----EDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFE 139 ++ ++++ L E+ + +++ QK+ + +E+ + LE+ KRA +L+ + Sbjct: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA-NLDKNK 1226 Query: 140 QRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEA 199 Q L + NA L EL + + K E +++L Q ++ + + A Sbjct: 1227 QTLEK---ENADLAGEL-------RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1276 Query: 200 ERTDTAVQATGSVPS 214 E D + V S Sbjct: 1277 ELNDKVHKLQNEVES 1291 Score = 35.4 bits (80), Expect = 0.072 Identities = 35/187 (18%), Positives = 87/187 (46%), Gaps = 10/187 (5%) Query: 1 MEDSGKTFSSEEEE-ANYWKDLAMTYKQRAENTQEELREFQEG---SREYEAELETQLQQ 56 +E+ K F E E +++ A Y + E T+ L++ + + + +L + L++ Sbjct: 1390 LEEGKKRFQKEIENLTQQYEEKAAAY-DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1448 Query: 57 IETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRE 116 + + LL+E + + +++ E + E + +L L + K++L++ + Sbjct: 1449 KQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKM 1508 Query: 117 LEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDL 176 L+ +DL +K ++ + E+ + ++++L+E E+ L++ + K L Sbjct: 1509 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAK-----L 1563 Query: 177 RQELAVQ 183 R E+ +Q Sbjct: 1564 RLEVNMQ 1570 Score = 31.6 bits (70), Expect = 1.0 Identities = 33/163 (20%), Positives = 69/163 (42%), Gaps = 27/163 (16%) Query: 28 RAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHS 87 R E + + + ++E + + E +L+++E ++ L E N L+ +L+ E + Sbjct: 849 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY----- 903 Query: 88 EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQ-AI 146 + E+ + A K +L++ + E+E LE+ E R Q Sbjct: 904 ------AEAEEMRVRLAAKKQELEEILHEMEAR--------------LEEEEDRGQQLQA 943 Query: 147 ERNAFLESELDEKENL-LESVQRLKDEARDLRQELAVQQKQEK 188 ER + LD +E L E R K + + E +++ +++ Sbjct: 944 ERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 986 Score = 30.4 bits (67), Expect = 2.3 Identities = 18/77 (23%), Positives = 34/77 (44%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 +ED K +E+A K++ E +EE + R+ + EL+ + E Sbjct: 1858 VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAM 1917 Query: 61 NRDLLSENNRLRMELET 77 R++ + ++LR ET Sbjct: 1918 GREVNALKSKLRRGNET 1934 Score = 28.5 bits (62), Expect = 8.8 Identities = 31/146 (21%), Positives = 66/146 (45%), Gaps = 13/146 (8%) Query: 27 QRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQH 86 Q E ++E RE Q ++ L+Q + + +++L + R E KE+ E + Sbjct: 1825 QLEEQVEQEAREKQAATKS--------LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1876 Query: 87 SEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAI 146 + + LE+ +++ I +K REL++A + E R + +L+ +R N+ Sbjct: 1877 ARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGR-EVNALKSKLRRGNE-- 1933 Query: 147 ERNAFLESELDEKENLLESVQRLKDE 172 +F+ S ++E+ ++E Sbjct: 1934 --TSFVPSRRSGGRRVIENADGSEEE 1957 >gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo sapiens] Length = 1979 Score = 52.8 bits (125), Expect = 4e-07 Identities = 46/196 (23%), Positives = 86/196 (43%), Gaps = 6/196 (3%) Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL 71 +EE + +Q+ EEL E E + +A L+ Q +E N DL E L Sbjct: 1191 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1250 Query: 72 ---RMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128 + E+E K+K E Q E + S E A+ + D++ K E+E L A+ Sbjct: 1251 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVTGMLNEAE 1307 Query: 129 RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188 I +D +Q + L+ E +K N+ +++L++E L+ +L + + ++ Sbjct: 1308 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1367 Query: 189 PRTPMPSSVEAERTDT 204 S++ + +D+ Sbjct: 1368 NLERHISTLNIQLSDS 1383 Score = 49.3 bits (116), Expect = 5e-06 Identities = 44/199 (22%), Positives = 92/199 (46%), Gaps = 22/199 (11%) Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70 +EEE +D K+R + + EL+E ++ + E +Q++ +L +E Sbjct: 857 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEE 915 Query: 71 LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR- 129 +R+ L K++ E E ++ ED Q +A + ++ + + +LE+ ++ E A++ Sbjct: 916 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 975 Query: 130 ---------ATIMSLED----FEQRLNQAIERNAFLE-------SELDEKENLLESVQRL 169 A I LED + + N+ + LE + L E+E +++ +L Sbjct: 976 LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKL 1035 Query: 170 KDEARDLRQELAVQQKQEK 188 K++ + EL V+ K+E+ Sbjct: 1036 KNKHESMISELEVRLKKEE 1054 Score = 44.3 bits (103), Expect = 2e-04 Identities = 48/179 (26%), Positives = 83/179 (46%), Gaps = 26/179 (14%) Query: 11 EEEEANY--WKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSEN 68 EEE+ N D Q+AE EL R + E+ QQ+E +N++L S+ Sbjct: 1753 EEEQGNMEAMSDRVRKATQQAEQLSNELAT----ERSTAQKNESARQQLERQNKELRSKL 1808 Query: 69 NRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL---E 125 + + +K KF+ I+ALE +AQ +++Q+++ RE + A L + Sbjct: 1809 HEME---GAVKSKFK-------STIAALEAKIAQ---LEEQVEQEAREKQAATKSLKQKD 1855 Query: 126 RAKRATIMSLED----FEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180 + + ++ +ED EQ QA + NA ++ + E E QR+ R L++EL Sbjct: 1856 KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1914 Score = 43.9 bits (102), Expect = 2e-04 Identities = 48/213 (22%), Positives = 90/213 (42%), Gaps = 26/213 (12%) Query: 2 EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEEL------REFQEGSREYEAELETQLQ 55 E GK ++ A+ L T + E T+++L R+ +E + +L+ +++ Sbjct: 1305 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME 1364 Query: 56 QIETRNRDL------LSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQ 109 + R + LS++ + + + E E ++I L + A D+ Sbjct: 1365 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1424 Query: 110 LQKYIRELEQANDDLE---RAKRATIMSLEDFEQRLNQ--AIERNAF---------LESE 155 L+K L+Q DDL +R + +LE +++ +Q A E+N E+E Sbjct: 1425 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1484 Query: 156 LDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188 EKE S+ R +EA + ++EL K K Sbjct: 1485 AREKETKALSLARALEEALEAKEELERTNKMLK 1517 Score = 43.1 bits (100), Expect = 3e-04 Identities = 51/204 (25%), Positives = 91/204 (44%), Gaps = 29/204 (14%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 + D + EEE+A L ++ + L++ +E SR+ ELE +++E Sbjct: 1015 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK-EEKSRQ---ELEKLKRKLEGD 1070 Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120 D + L+ ++ +K + + E ++ L+D++AQ K+ K IRELE Sbjct: 1071 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ----KNNALKKIRELEGH 1126 Query: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180 DL+ ED + ER A ++E +K +L E ++ LK E D Sbjct: 1127 ISDLQ----------EDLDS------ERAARNKAE-KQKRDLGEELEALKTELEDTLDST 1169 Query: 181 AVQQ----KQEKPRTPMPSSVEAE 200 A QQ K+E+ T + +++ E Sbjct: 1170 ATQQELRAKREQEVTVLKKALDEE 1193 Score = 42.4 bits (98), Expect = 6e-04 Identities = 38/175 (21%), Positives = 73/175 (41%), Gaps = 11/175 (6%) Query: 21 LAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELET--- 77 LA ++R + + FQ R Y A +Q + ++ N ++L Sbjct: 782 LAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQW 841 Query: 78 ------IKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRAT 131 +K +V E ++ A ED+L +TK + + + ++ELEQ + L K Sbjct: 842 WRLFTKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLL 899 Query: 132 IMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186 L+ + +A E L ++ E E +L ++ +E D Q+L ++K+ Sbjct: 900 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 954 Score = 42.4 bits (98), Expect = 6e-04 Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 29/208 (13%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 +E + K +E E+ KD E ++ L E + ELE +LQ E Sbjct: 1509 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE-- 1566 Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120 RL + ++ +K +FE R + A ++ Q + + QLQ+ + E E Sbjct: 1567 -----DAKLRLEVNMQALKGQFE-------RDLQARDE---QNEEKRRQLQRQLHEYETE 1611 Query: 121 NDDLERAKRATIMS--------LEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDE 172 +D ER +RA + L+D E + + AI+ +L + + ++ QR ++ Sbjct: 1612 LED-ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1670 Query: 173 ARDLRQELAVQQKQEKPRTPMPSSVEAE 200 AR R E+ K+ + + S+EA+ Sbjct: 1671 ARASRDEIFATAKENEKKA---KSLEAD 1695 Score = 42.0 bits (97), Expect = 8e-04 Identities = 49/224 (21%), Positives = 94/224 (41%), Gaps = 24/224 (10%) Query: 4 SGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRN-- 61 +G +E + KD+A Q ++TQE L QE +R+ + + T+L+Q+E Sbjct: 1300 TGMLNEAEGKAIKLAKDVASLSSQ-LQDTQELL---QEETRQ-KLNVSTKLRQLEEERNS 1354 Query: 62 -RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ- 119 +D L E + LE +Q S+ +++ + + K + QK I L Q Sbjct: 1355 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1414 Query: 120 ------ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEA 173 A D LE+ K L+D L+ + + LE + + + LL + + + Sbjct: 1415 YEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKY 1474 Query: 174 RDLRQELAVQQKQEKPRT---------PMPSSVEAERTDTAVQA 208 D R + ++++ + + + E ERT+ ++A Sbjct: 1475 ADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKA 1518 Score = 41.6 bits (96), Expect = 0.001 Identities = 36/174 (20%), Positives = 78/174 (44%), Gaps = 18/174 (10%) Query: 29 AENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMEL----------ETI 78 AE + L ++ E E+E +L++ E R + L +E ++ ++ E Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 972 Query: 79 KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL------ERAKRATI 132 ++K +++ +I LED++ ++L K + LE+ DL E K + Sbjct: 973 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032 Query: 133 MSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186 L++ + + +E L+ E ++ L + ++L+ +A D +++A Q Q Sbjct: 1033 TKLKNKHESMISELE--VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1084 Score = 40.0 bits (92), Expect = 0.003 Identities = 41/203 (20%), Positives = 90/203 (44%), Gaps = 14/203 (6%) Query: 1 MEDS-GKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIET 59 +ED+ T + +E A +++ + K E T+ + QE +++ +E +Q+E Sbjct: 1162 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE- 1220 Query: 60 RNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ 119 + R + L+ K+ E ++++ ++ L + + K +L+ ++EL+ Sbjct: 1221 -------QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS 1273 Query: 120 ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKE-NLLESVQRLKDEARDLRQ 178 D ERA+ L D +L +E + +E + K L + V L + +D ++ Sbjct: 1274 KCSDGERAR----AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1329 Query: 179 ELAVQQKQEKPRTPMPSSVEAER 201 L + +Q+ + +E ER Sbjct: 1330 LLQEETRQKLNVSTKLRQLEEER 1352 Score = 36.6 bits (83), Expect = 0.032 Identities = 47/233 (20%), Positives = 87/233 (37%), Gaps = 20/233 (8%) Query: 19 KDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETI 78 + L +++ + L E + S +Y E + + + LS L LE Sbjct: 1447 RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA- 1505 Query: 79 KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDF 138 KE+ E + + + A +DL +K D + K + ELE++ LE LE+ Sbjct: 1506 KEELERTN----KMLKAEMEDLVSSK---DDVGKNVHELEKSKRALETQMEEMKTQLEEL 1558 Query: 139 EQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQ------------ELAVQQKQ 186 E L + LE + + E + +DE + ++ EL ++KQ Sbjct: 1559 EDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ 1618 Query: 187 EKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDS 239 +E + D +QA ++ A + F+R L+D+ Sbjct: 1619 RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1671 Score = 36.2 bits (82), Expect = 0.042 Identities = 41/195 (21%), Positives = 86/195 (44%), Gaps = 22/195 (11%) Query: 31 NTQEELREFQEGSREYEAELETQL---QQIETRNRDLLSENNRLRMELETIKEKFEVQH- 86 N +++RE + + + +L+++ + E + RDL E L+ ELE + Q Sbjct: 1115 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1174 Query: 87 --SEGYRQISAL-----EDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFE 139 ++ ++++ L E+ + +++ QK+ + +E+ + LE+ KRA +L+ + Sbjct: 1175 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA-NLDKNK 1233 Query: 140 QRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEA 199 Q L + NA L EL + + K E +++L Q ++ + + A Sbjct: 1234 QTLEK---ENADLAGEL-------RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1283 Query: 200 ERTDTAVQATGSVPS 214 E D + V S Sbjct: 1284 ELNDKVHKLQNEVES 1298 Score = 35.4 bits (80), Expect = 0.072 Identities = 35/187 (18%), Positives = 87/187 (46%), Gaps = 10/187 (5%) Query: 1 MEDSGKTFSSEEEE-ANYWKDLAMTYKQRAENTQEELREFQEG---SREYEAELETQLQQ 56 +E+ K F E E +++ A Y + E T+ L++ + + + +L + L++ Sbjct: 1397 LEEGKKRFQKEIENLTQQYEEKAAAY-DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1455 Query: 57 IETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRE 116 + + LL+E + + +++ E + E + +L L + K++L++ + Sbjct: 1456 KQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKM 1515 Query: 117 LEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDL 176 L+ +DL +K ++ + E+ + ++++L+E E+ L++ + K L Sbjct: 1516 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAK-----L 1570 Query: 177 RQELAVQ 183 R E+ +Q Sbjct: 1571 RLEVNMQ 1577 Score = 31.6 bits (70), Expect = 1.0 Identities = 33/163 (20%), Positives = 69/163 (42%), Gaps = 27/163 (16%) Query: 28 RAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHS 87 R E + + + ++E + + E +L+++E ++ L E N L+ +L+ E + Sbjct: 856 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY----- 910 Query: 88 EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQ-AI 146 + E+ + A K +L++ + E+E LE+ E R Q Sbjct: 911 ------AEAEEMRVRLAAKKQELEEILHEMEAR--------------LEEEEDRGQQLQA 950 Query: 147 ERNAFLESELDEKENL-LESVQRLKDEARDLRQELAVQQKQEK 188 ER + LD +E L E R K + + E +++ +++ Sbjct: 951 ERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 993 Score = 30.4 bits (67), Expect = 2.3 Identities = 18/77 (23%), Positives = 34/77 (44%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 +ED K +E+A K++ E +EE + R+ + EL+ + E Sbjct: 1865 VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAM 1924 Query: 61 NRDLLSENNRLRMELET 77 R++ + ++LR ET Sbjct: 1925 GREVNALKSKLRRGNET 1941 Score = 28.5 bits (62), Expect = 8.8 Identities = 31/146 (21%), Positives = 66/146 (45%), Gaps = 13/146 (8%) Query: 27 QRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQH 86 Q E ++E RE Q ++ L+Q + + +++L + R E KE+ E + Sbjct: 1832 QLEEQVEQEAREKQAATKS--------LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1883 Query: 87 SEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAI 146 + + LE+ +++ I +K REL++A + E R + +L+ +R N+ Sbjct: 1884 ARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGR-EVNALKSKLRRGNE-- 1940 Query: 147 ERNAFLESELDEKENLLESVQRLKDE 172 +F+ S ++E+ ++E Sbjct: 1941 --TSFVPSRRSGGRRVIENADGSEEE 1964 >gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo sapiens] Length = 1945 Score = 52.8 bits (125), Expect = 4e-07 Identities = 46/196 (23%), Positives = 86/196 (43%), Gaps = 6/196 (3%) Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL 71 +EE + +Q+ EEL E E + +A L+ Q +E N DL E L Sbjct: 1191 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1250 Query: 72 ---RMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128 + E+E K+K E Q E + S E A+ + D++ K E+E L A+ Sbjct: 1251 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVTGMLNEAE 1307 Query: 129 RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188 I +D +Q + L+ E +K N+ +++L++E L+ +L + + ++ Sbjct: 1308 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1367 Query: 189 PRTPMPSSVEAERTDT 204 S++ + +D+ Sbjct: 1368 NLERHISTLNIQLSDS 1383 Score = 49.3 bits (116), Expect = 5e-06 Identities = 44/199 (22%), Positives = 92/199 (46%), Gaps = 22/199 (11%) Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70 +EEE +D K+R + + EL+E ++ + E +Q++ +L +E Sbjct: 857 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEE 915 Query: 71 LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR- 129 +R+ L K++ E E ++ ED Q +A + ++ + + +LE+ ++ E A++ Sbjct: 916 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 975 Query: 130 ---------ATIMSLED----FEQRLNQAIERNAFLE-------SELDEKENLLESVQRL 169 A I LED + + N+ + LE + L E+E +++ +L Sbjct: 976 LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKL 1035 Query: 170 KDEARDLRQELAVQQKQEK 188 K++ + EL V+ K+E+ Sbjct: 1036 KNKHESMISELEVRLKKEE 1054 Score = 44.3 bits (103), Expect = 2e-04 Identities = 48/179 (26%), Positives = 83/179 (46%), Gaps = 26/179 (14%) Query: 11 EEEEANY--WKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSEN 68 EEE+ N D Q+AE EL R + E+ QQ+E +N++L S+ Sbjct: 1753 EEEQGNMEAMSDRVRKATQQAEQLSNELAT----ERSTAQKNESARQQLERQNKELRSKL 1808 Query: 69 NRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL---E 125 + + +K KF+ I+ALE +AQ +++Q+++ RE + A L + Sbjct: 1809 HEME---GAVKSKFK-------STIAALEAKIAQ---LEEQVEQEAREKQAATKSLKQKD 1855 Query: 126 RAKRATIMSLED----FEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180 + + ++ +ED EQ QA + NA ++ + E E QR+ R L++EL Sbjct: 1856 KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1914 Score = 43.9 bits (102), Expect = 2e-04 Identities = 48/213 (22%), Positives = 90/213 (42%), Gaps = 26/213 (12%) Query: 2 EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEEL------REFQEGSREYEAELETQLQ 55 E GK ++ A+ L T + E T+++L R+ +E + +L+ +++ Sbjct: 1305 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME 1364 Query: 56 QIETRNRDL------LSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQ 109 + R + LS++ + + + E E ++I L + A D+ Sbjct: 1365 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1424 Query: 110 LQKYIRELEQANDDLE---RAKRATIMSLEDFEQRLNQ--AIERNAF---------LESE 155 L+K L+Q DDL +R + +LE +++ +Q A E+N E+E Sbjct: 1425 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1484 Query: 156 LDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188 EKE S+ R +EA + ++EL K K Sbjct: 1485 AREKETKALSLARALEEALEAKEELERTNKMLK 1517 Score = 43.1 bits (100), Expect = 3e-04 Identities = 51/204 (25%), Positives = 91/204 (44%), Gaps = 29/204 (14%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 + D + EEE+A L ++ + L++ +E SR+ ELE +++E Sbjct: 1015 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK-EEKSRQ---ELEKLKRKLEGD 1070 Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120 D + L+ ++ +K + + E ++ L+D++AQ K+ K IRELE Sbjct: 1071 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ----KNNALKKIRELEGH 1126 Query: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180 DL+ ED + ER A ++E +K +L E ++ LK E D Sbjct: 1127 ISDLQ----------EDLDS------ERAARNKAE-KQKRDLGEELEALKTELEDTLDST 1169 Query: 181 AVQQ----KQEKPRTPMPSSVEAE 200 A QQ K+E+ T + +++ E Sbjct: 1170 ATQQELRAKREQEVTVLKKALDEE 1193 Score = 42.4 bits (98), Expect = 6e-04 Identities = 38/175 (21%), Positives = 73/175 (41%), Gaps = 11/175 (6%) Query: 21 LAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELET--- 77 LA ++R + + FQ R Y A +Q + ++ N ++L Sbjct: 782 LAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQW 841 Query: 78 ------IKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRAT 131 +K +V E ++ A ED+L +TK + + + ++ELEQ + L K Sbjct: 842 WRLFTKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLL 899 Query: 132 IMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186 L+ + +A E L ++ E E +L ++ +E D Q+L ++K+ Sbjct: 900 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 954 Score = 42.4 bits (98), Expect = 6e-04 Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 29/208 (13%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 +E + K +E E+ KD E ++ L E + ELE +LQ E Sbjct: 1509 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE-- 1566 Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120 RL + ++ +K +FE R + A ++ Q + + QLQ+ + E E Sbjct: 1567 -----DAKLRLEVNMQALKGQFE-------RDLQARDE---QNEEKRRQLQRQLHEYETE 1611 Query: 121 NDDLERAKRATIMS--------LEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDE 172 +D ER +RA + L+D E + + AI+ +L + + ++ QR ++ Sbjct: 1612 LED-ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1670 Query: 173 ARDLRQELAVQQKQEKPRTPMPSSVEAE 200 AR R E+ K+ + + S+EA+ Sbjct: 1671 ARASRDEIFATAKENEKKA---KSLEAD 1695 Score = 42.0 bits (97), Expect = 8e-04 Identities = 49/224 (21%), Positives = 94/224 (41%), Gaps = 24/224 (10%) Query: 4 SGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRN-- 61 +G +E + KD+A Q ++TQE L QE +R+ + + T+L+Q+E Sbjct: 1300 TGMLNEAEGKAIKLAKDVASLSSQ-LQDTQELL---QEETRQ-KLNVSTKLRQLEEERNS 1354 Query: 62 -RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ- 119 +D L E + LE +Q S+ +++ + + K + QK I L Q Sbjct: 1355 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1414 Query: 120 ------ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEA 173 A D LE+ K L+D L+ + + LE + + + LL + + + Sbjct: 1415 YEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKY 1474 Query: 174 RDLRQELAVQQKQEKPRT---------PMPSSVEAERTDTAVQA 208 D R + ++++ + + + E ERT+ ++A Sbjct: 1475 ADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKA 1518 Score = 41.6 bits (96), Expect = 0.001 Identities = 36/174 (20%), Positives = 78/174 (44%), Gaps = 18/174 (10%) Query: 29 AENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMEL----------ETI 78 AE + L ++ E E+E +L++ E R + L +E ++ ++ E Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 972 Query: 79 KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL------ERAKRATI 132 ++K +++ +I LED++ ++L K + LE+ DL E K + Sbjct: 973 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032 Query: 133 MSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186 L++ + + +E L+ E ++ L + ++L+ +A D +++A Q Q Sbjct: 1033 TKLKNKHESMISELE--VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1084 Score = 40.0 bits (92), Expect = 0.003 Identities = 41/203 (20%), Positives = 90/203 (44%), Gaps = 14/203 (6%) Query: 1 MEDS-GKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIET 59 +ED+ T + +E A +++ + K E T+ + QE +++ +E +Q+E Sbjct: 1162 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE- 1220 Query: 60 RNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ 119 + R + L+ K+ E ++++ ++ L + + K +L+ ++EL+ Sbjct: 1221 -------QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS 1273 Query: 120 ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKE-NLLESVQRLKDEARDLRQ 178 D ERA+ L D +L +E + +E + K L + V L + +D ++ Sbjct: 1274 KCSDGERAR----AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1329 Query: 179 ELAVQQKQEKPRTPMPSSVEAER 201 L + +Q+ + +E ER Sbjct: 1330 LLQEETRQKLNVSTKLRQLEEER 1352 Score = 36.6 bits (83), Expect = 0.032 Identities = 47/233 (20%), Positives = 87/233 (37%), Gaps = 20/233 (8%) Query: 19 KDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETI 78 + L +++ + L E + S +Y E + + + LS L LE Sbjct: 1447 RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA- 1505 Query: 79 KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDF 138 KE+ E + + + A +DL +K D + K + ELE++ LE LE+ Sbjct: 1506 KEELERTN----KMLKAEMEDLVSSK---DDVGKNVHELEKSKRALETQMEEMKTQLEEL 1558 Query: 139 EQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQ------------ELAVQQKQ 186 E L + LE + + E + +DE + ++ EL ++KQ Sbjct: 1559 EDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ 1618 Query: 187 EKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDS 239 +E + D +QA ++ A + F+R L+D+ Sbjct: 1619 RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1671 Score = 36.2 bits (82), Expect = 0.042 Identities = 41/195 (21%), Positives = 86/195 (44%), Gaps = 22/195 (11%) Query: 31 NTQEELREFQEGSREYEAELETQL---QQIETRNRDLLSENNRLRMELETIKEKFEVQH- 86 N +++RE + + + +L+++ + E + RDL E L+ ELE + Q Sbjct: 1115 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1174 Query: 87 --SEGYRQISAL-----EDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFE 139 ++ ++++ L E+ + +++ QK+ + +E+ + LE+ KRA +L+ + Sbjct: 1175 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA-NLDKNK 1233 Query: 140 QRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEA 199 Q L + NA L EL + + K E +++L Q ++ + + A Sbjct: 1234 QTLEK---ENADLAGEL-------RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1283 Query: 200 ERTDTAVQATGSVPS 214 E D + V S Sbjct: 1284 ELNDKVHKLQNEVES 1298 Score = 35.4 bits (80), Expect = 0.072 Identities = 35/187 (18%), Positives = 87/187 (46%), Gaps = 10/187 (5%) Query: 1 MEDSGKTFSSEEEE-ANYWKDLAMTYKQRAENTQEELREFQEG---SREYEAELETQLQQ 56 +E+ K F E E +++ A Y + E T+ L++ + + + +L + L++ Sbjct: 1397 LEEGKKRFQKEIENLTQQYEEKAAAY-DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1455 Query: 57 IETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRE 116 + + LL+E + + +++ E + E + +L L + K++L++ + Sbjct: 1456 KQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKM 1515 Query: 117 LEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDL 176 L+ +DL +K ++ + E+ + ++++L+E E+ L++ + K L Sbjct: 1516 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAK-----L 1570 Query: 177 RQELAVQ 183 R E+ +Q Sbjct: 1571 RLEVNMQ 1577 Score = 31.6 bits (70), Expect = 1.0 Identities = 33/163 (20%), Positives = 69/163 (42%), Gaps = 27/163 (16%) Query: 28 RAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHS 87 R E + + + ++E + + E +L+++E ++ L E N L+ +L+ E + Sbjct: 856 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY----- 910 Query: 88 EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQ-AI 146 + E+ + A K +L++ + E+E LE+ E R Q Sbjct: 911 ------AEAEEMRVRLAAKKQELEEILHEMEAR--------------LEEEEDRGQQLQA 950 Query: 147 ERNAFLESELDEKENL-LESVQRLKDEARDLRQELAVQQKQEK 188 ER + LD +E L E R K + + E +++ +++ Sbjct: 951 ERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 993 Score = 28.9 bits (63), Expect = 6.8 Identities = 16/72 (22%), Positives = 32/72 (44%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 +ED K +E+A K++ E +EE + R+ + EL+ + E Sbjct: 1865 VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAM 1924 Query: 61 NRDLLSENNRLR 72 R++ + ++LR Sbjct: 1925 GREVNALKSKLR 1936 Score = 28.5 bits (62), Expect = 8.8 Identities = 24/107 (22%), Positives = 51/107 (47%), Gaps = 11/107 (10%) Query: 27 QRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQH 86 Q E ++E RE Q ++ L+Q + + +++L + R E KE+ E + Sbjct: 1832 QLEEQVEQEAREKQAATKS--------LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1883 Query: 87 S---EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRA 130 + + RQ+ E++ + A + +LQ+ + E ++N+ + R A Sbjct: 1884 ARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA 1930 >gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo sapiens] Length = 1938 Score = 52.8 bits (125), Expect = 4e-07 Identities = 46/196 (23%), Positives = 86/196 (43%), Gaps = 6/196 (3%) Query: 12 EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL 71 +EE + +Q+ EEL E E + +A L+ Q +E N DL E L Sbjct: 1184 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1243 Query: 72 ---RMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128 + E+E K+K E Q E + S E A+ + D++ K E+E L A+ Sbjct: 1244 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVTGMLNEAE 1300 Query: 129 RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188 I +D +Q + L+ E +K N+ +++L++E L+ +L + + ++ Sbjct: 1301 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1360 Query: 189 PRTPMPSSVEAERTDT 204 S++ + +D+ Sbjct: 1361 NLERHISTLNIQLSDS 1376 Score = 49.3 bits (116), Expect = 5e-06 Identities = 44/199 (22%), Positives = 92/199 (46%), Gaps = 22/199 (11%) Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70 +EEE +D K+R + + EL+E ++ + E +Q++ +L +E Sbjct: 850 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEE 908 Query: 71 LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR- 129 +R+ L K++ E E ++ ED Q +A + ++ + + +LE+ ++ E A++ Sbjct: 909 MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 968 Query: 130 ---------ATIMSLED----FEQRLNQAIERNAFLE-------SELDEKENLLESVQRL 169 A I LED + + N+ + LE + L E+E +++ +L Sbjct: 969 LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKL 1028 Query: 170 KDEARDLRQELAVQQKQEK 188 K++ + EL V+ K+E+ Sbjct: 1029 KNKHESMISELEVRLKKEE 1047 Score = 44.3 bits (103), Expect = 2e-04 Identities = 48/179 (26%), Positives = 83/179 (46%), Gaps = 26/179 (14%) Query: 11 EEEEANY--WKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSEN 68 EEE+ N D Q+AE EL R + E+ QQ+E +N++L S+ Sbjct: 1746 EEEQGNMEAMSDRVRKATQQAEQLSNELAT----ERSTAQKNESARQQLERQNKELRSKL 1801 Query: 69 NRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL---E 125 + + +K KF+ I+ALE +AQ +++Q+++ RE + A L + Sbjct: 1802 HEME---GAVKSKFK-------STIAALEAKIAQ---LEEQVEQEAREKQAATKSLKQKD 1848 Query: 126 RAKRATIMSLED----FEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180 + + ++ +ED EQ QA + NA ++ + E E QR+ R L++EL Sbjct: 1849 KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1907 Score = 43.9 bits (102), Expect = 2e-04 Identities = 48/213 (22%), Positives = 90/213 (42%), Gaps = 26/213 (12%) Query: 2 EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEEL------REFQEGSREYEAELETQLQ 55 E GK ++ A+ L T + E T+++L R+ +E + +L+ +++ Sbjct: 1298 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME 1357 Query: 56 QIETRNRDL------LSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQ 109 + R + LS++ + + + E E ++I L + A D+ Sbjct: 1358 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1417 Query: 110 LQKYIRELEQANDDLE---RAKRATIMSLEDFEQRLNQ--AIERNAF---------LESE 155 L+K L+Q DDL +R + +LE +++ +Q A E+N E+E Sbjct: 1418 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1477 Query: 156 LDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188 EKE S+ R +EA + ++EL K K Sbjct: 1478 AREKETKALSLARALEEALEAKEELERTNKMLK 1510 Score = 43.1 bits (100), Expect = 3e-04 Identities = 51/204 (25%), Positives = 91/204 (44%), Gaps = 29/204 (14%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 + D + EEE+A L ++ + L++ +E SR+ ELE +++E Sbjct: 1008 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK-EEKSRQ---ELEKLKRKLEGD 1063 Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120 D + L+ ++ +K + + E ++ L+D++AQ K+ K IRELE Sbjct: 1064 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ----KNNALKKIRELEGH 1119 Query: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180 DL+ ED + ER A ++E +K +L E ++ LK E D Sbjct: 1120 ISDLQ----------EDLDS------ERAARNKAE-KQKRDLGEELEALKTELEDTLDST 1162 Query: 181 AVQQ----KQEKPRTPMPSSVEAE 200 A QQ K+E+ T + +++ E Sbjct: 1163 ATQQELRAKREQEVTVLKKALDEE 1186 Score = 42.4 bits (98), Expect = 6e-04 Identities = 38/175 (21%), Positives = 73/175 (41%), Gaps = 11/175 (6%) Query: 21 LAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELET--- 77 LA ++R + + FQ R Y A +Q + ++ N ++L Sbjct: 775 LAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQW 834 Query: 78 ------IKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRAT 131 +K +V E ++ A ED+L +TK + + + ++ELEQ + L K Sbjct: 835 WRLFTKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLL 892 Query: 132 IMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186 L+ + +A E L ++ E E +L ++ +E D Q+L ++K+ Sbjct: 893 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 947 Score = 42.4 bits (98), Expect = 6e-04 Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 29/208 (13%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 +E + K +E E+ KD E ++ L E + ELE +LQ E Sbjct: 1502 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE-- 1559 Query: 61 NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120 RL + ++ +K +FE R + A ++ Q + + QLQ+ + E E Sbjct: 1560 -----DAKLRLEVNMQALKGQFE-------RDLQARDE---QNEEKRRQLQRQLHEYETE 1604 Query: 121 NDDLERAKRATIMS--------LEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDE 172 +D ER +RA + L+D E + + AI+ +L + + ++ QR ++ Sbjct: 1605 LED-ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1663 Query: 173 ARDLRQELAVQQKQEKPRTPMPSSVEAE 200 AR R E+ K+ + + S+EA+ Sbjct: 1664 ARASRDEIFATAKENEKKA---KSLEAD 1688 Score = 42.0 bits (97), Expect = 8e-04 Identities = 49/224 (21%), Positives = 94/224 (41%), Gaps = 24/224 (10%) Query: 4 SGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRN-- 61 +G +E + KD+A Q ++TQE L QE +R+ + + T+L+Q+E Sbjct: 1293 TGMLNEAEGKAIKLAKDVASLSSQ-LQDTQELL---QEETRQ-KLNVSTKLRQLEEERNS 1347 Query: 62 -RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ- 119 +D L E + LE +Q S+ +++ + + K + QK I L Q Sbjct: 1348 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1407 Query: 120 ------ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEA 173 A D LE+ K L+D L+ + + LE + + + LL + + + Sbjct: 1408 YEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKY 1467 Query: 174 RDLRQELAVQQKQEKPRT---------PMPSSVEAERTDTAVQA 208 D R + ++++ + + + E ERT+ ++A Sbjct: 1468 ADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKA 1511 Score = 41.6 bits (96), Expect = 0.001 Identities = 36/174 (20%), Positives = 78/174 (44%), Gaps = 18/174 (10%) Query: 29 AENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMEL----------ETI 78 AE + L ++ E E+E +L++ E R + L +E ++ ++ E Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 965 Query: 79 KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL------ERAKRATI 132 ++K +++ +I LED++ ++L K + LE+ DL E K + Sbjct: 966 RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025 Query: 133 MSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186 L++ + + +E L+ E ++ L + ++L+ +A D +++A Q Q Sbjct: 1026 TKLKNKHESMISELE--VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1077 Score = 40.0 bits (92), Expect = 0.003 Identities = 41/203 (20%), Positives = 90/203 (44%), Gaps = 14/203 (6%) Query: 1 MEDS-GKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIET 59 +ED+ T + +E A +++ + K E T+ + QE +++ +E +Q+E Sbjct: 1155 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE- 1213 Query: 60 RNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ 119 + R + L+ K+ E ++++ ++ L + + K +L+ ++EL+ Sbjct: 1214 -------QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS 1266 Query: 120 ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKE-NLLESVQRLKDEARDLRQ 178 D ERA+ L D +L +E + +E + K L + V L + +D ++ Sbjct: 1267 KCSDGERAR----AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1322 Query: 179 ELAVQQKQEKPRTPMPSSVEAER 201 L + +Q+ + +E ER Sbjct: 1323 LLQEETRQKLNVSTKLRQLEEER 1345 Score = 36.6 bits (83), Expect = 0.032 Identities = 47/233 (20%), Positives = 87/233 (37%), Gaps = 20/233 (8%) Query: 19 KDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETI 78 + L +++ + L E + S +Y E + + + LS L LE Sbjct: 1440 RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA- 1498 Query: 79 KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDF 138 KE+ E + + + A +DL +K D + K + ELE++ LE LE+ Sbjct: 1499 KEELERTN----KMLKAEMEDLVSSK---DDVGKNVHELEKSKRALETQMEEMKTQLEEL 1551 Query: 139 EQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQ------------ELAVQQKQ 186 E L + LE + + E + +DE + ++ EL ++KQ Sbjct: 1552 EDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ 1611 Query: 187 EKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDS 239 +E + D +QA ++ A + F+R L+D+ Sbjct: 1612 RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1664 Score = 36.2 bits (82), Expect = 0.042 Identities = 41/195 (21%), Positives = 86/195 (44%), Gaps = 22/195 (11%) Query: 31 NTQEELREFQEGSREYEAELETQL---QQIETRNRDLLSENNRLRMELETIKEKFEVQH- 86 N +++RE + + + +L+++ + E + RDL E L+ ELE + Q Sbjct: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167 Query: 87 --SEGYRQISAL-----EDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFE 139 ++ ++++ L E+ + +++ QK+ + +E+ + LE+ KRA +L+ + Sbjct: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA-NLDKNK 1226 Query: 140 QRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEA 199 Q L + NA L EL + + K E +++L Q ++ + + A Sbjct: 1227 QTLEK---ENADLAGEL-------RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1276 Query: 200 ERTDTAVQATGSVPS 214 E D + V S Sbjct: 1277 ELNDKVHKLQNEVES 1291 Score = 35.4 bits (80), Expect = 0.072 Identities = 35/187 (18%), Positives = 87/187 (46%), Gaps = 10/187 (5%) Query: 1 MEDSGKTFSSEEEE-ANYWKDLAMTYKQRAENTQEELREFQEG---SREYEAELETQLQQ 56 +E+ K F E E +++ A Y + E T+ L++ + + + +L + L++ Sbjct: 1390 LEEGKKRFQKEIENLTQQYEEKAAAY-DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1448 Query: 57 IETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRE 116 + + LL+E + + +++ E + E + +L L + K++L++ + Sbjct: 1449 KQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKM 1508 Query: 117 LEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDL 176 L+ +DL +K ++ + E+ + ++++L+E E+ L++ + K L Sbjct: 1509 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAK-----L 1563 Query: 177 RQELAVQ 183 R E+ +Q Sbjct: 1564 RLEVNMQ 1570 Score = 31.6 bits (70), Expect = 1.0 Identities = 33/163 (20%), Positives = 69/163 (42%), Gaps = 27/163 (16%) Query: 28 RAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHS 87 R E + + + ++E + + E +L+++E ++ L E N L+ +L+ E + Sbjct: 849 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY----- 903 Query: 88 EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQ-AI 146 + E+ + A K +L++ + E+E LE+ E R Q Sbjct: 904 ------AEAEEMRVRLAAKKQELEEILHEMEAR--------------LEEEEDRGQQLQA 943 Query: 147 ERNAFLESELDEKENL-LESVQRLKDEARDLRQELAVQQKQEK 188 ER + LD +E L E R K + + E +++ +++ Sbjct: 944 ERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 986 Score = 28.9 bits (63), Expect = 6.8 Identities = 16/72 (22%), Positives = 32/72 (44%) Query: 1 MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60 +ED K +E+A K++ E +EE + R+ + EL+ + E Sbjct: 1858 VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAM 1917 Query: 61 NRDLLSENNRLR 72 R++ + ++LR Sbjct: 1918 GREVNALKSKLR 1929 Score = 28.5 bits (62), Expect = 8.8 Identities = 24/107 (22%), Positives = 51/107 (47%), Gaps = 11/107 (10%) Query: 27 QRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQH 86 Q E ++E RE Q ++ L+Q + + +++L + R E KE+ E + Sbjct: 1825 QLEEQVEQEAREKQAATKS--------LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1876 Query: 87 S---EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRA 130 + + RQ+ E++ + A + +LQ+ + E ++N+ + R A Sbjct: 1877 ARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA 1923 >gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo sapiens] Length = 1939 Score = 52.8 bits (125), Expect = 4e-07 Identities = 49/187 (26%), Positives = 88/187 (47%), Gaps = 21/187 (11%) Query: 26 KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85 K+R Q+ R+ +E + ++EA T + ++ D ++E L+ +K+K E + Sbjct: 1169 KKREAEFQKMRRDLEEATLQHEATAAT----LRKKHADSVAELGEQIDNLQRVKQKLEKE 1224 Query: 86 HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRL-NQ 144 SE +I L ++ K L+K R LE D L K + E+ +QRL N Sbjct: 1225 KSEMKMEIDDLASNMETVSKAKGNLEKMCRALE---DQLSEIK-----TKEEEQQRLIND 1276 Query: 145 AIERNAFLESE-------LDEKENLLESVQRLKDEARDLRQELAVQQKQE-KPRTPMPSS 196 + A L++E LDEK+ L+ + R K +EL Q ++E K ++ + + Sbjct: 1277 LTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHA 1336 Query: 197 VEAERTD 203 +++ R D Sbjct: 1337 LQSSRHD 1343 Score = 48.9 bits (115), Expect = 6e-06 Identities = 56/242 (23%), Positives = 108/242 (44%), Gaps = 47/242 (19%) Query: 10 SEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69 +EE++ N + +Q+ ++ EGS E E ++ L++ + + L Sbjct: 1016 AEEDKVNTLTKAKIKLEQQVDDL--------EGSLEQEKKIRMDLERAKRKLEGDLKLAQ 1067 Query: 70 RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL----- 124 M++E K++ + + + ++S L+ + +A+ QLQK I+EL+ ++L Sbjct: 1068 ESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIE 1127 Query: 125 -ERAKRATI--------MSLEDFEQRLNQA-------IERNAFLESELDE-KENLLESVQ 167 ERA RA LE+ +RL +A IE N E+E + + +L E+ Sbjct: 1128 AERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATL 1187 Query: 168 RLKDEARDLRQELA---------------VQQKQEKPRTPMPSSVE--AERTDTAVQATG 210 + + A LR++ A V+QK EK ++ M ++ A +T +A G Sbjct: 1188 QHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKG 1247 Query: 211 SV 212 ++ Sbjct: 1248 NL 1249 Score = 46.2 bits (108), Expect = 4e-05 Identities = 56/200 (28%), Positives = 90/200 (45%), Gaps = 46/200 (23%) Query: 11 EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAEL-------ETQLQQIETRNRD 63 ++++ N+ K LA +KQ+ E T EL Q+ SR EL E L Q+ET R Sbjct: 1447 DKKQRNFDKILA-EWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKR- 1504 Query: 64 LLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDD 123 EN L+ E+ + E Q +EG ++I LE K +++EQ + Sbjct: 1505 ---ENKNLQQEISDLTE----QIAEGGKRIHELE--------------KIKKQVEQEKSE 1543 Query: 124 LERAKRATIMSLEDFEQR-------LNQA---IERN-AFLESELDEKE----NLLESVQR 168 L+ A SLE E + LNQ ++R A + E+D+ + ++ES+Q Sbjct: 1544 LQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQS 1603 Query: 169 LKD-EARDLRQELAVQQKQE 187 D E R + +++K E Sbjct: 1604 TLDAEIRSRNDAIRLKKKME 1623 Score = 43.1 bits (100), Expect = 3e-04 Identities = 32/118 (27%), Positives = 63/118 (53%), Gaps = 22/118 (18%) Query: 74 ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIM 133 E+ +KE+FE +++LA+T+A + +L++ + L Q +DL+ +A Sbjct: 852 EMANMKEEFE-----------KTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEAD 900 Query: 134 SLEDFEQRLNQAIERNAFLESEL--------DEKE---NLLESVQRLKDEARDLRQEL 180 SL D E+R +Q I+ LE+++ DE+E L ++L+DE +L++++ Sbjct: 901 SLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 958 Score = 37.0 bits (84), Expect = 0.025 Identities = 33/158 (20%), Positives = 71/158 (44%), Gaps = 22/158 (13%) Query: 25 YKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL---RMELETIKEK 81 Y ++ + + + G + + ++E +Q+E + + + L R + + ++E+ Sbjct: 1291 YSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQ 1350 Query: 82 FEVQH---SEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDF 138 +E + +E R +S ++AQ + KY + Q ++LE AK+ L+D Sbjct: 1351 YEEEQEAKAELQRAMSKANSEVAQWRT------KYETDAIQRTEELEEAKKKLAQRLQDA 1404 Query: 139 EQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDL 176 E+ + + A LE ++ QRL++E DL Sbjct: 1405 EEHVEAVNAKCASLE----------KTKQRLQNEVEDL 1432 Score = 32.0 bits (71), Expect = 0.80 Identities = 46/215 (21%), Positives = 87/215 (40%), Gaps = 40/215 (18%) Query: 11 EEEEANYWKDLAMTYKQRAENTQ---EELREFQEGSREYEAELETQLQQIE----TRNRD 63 EE EA+ + + + E Q E R+ E E + ++ +E T + + Sbjct: 1549 EEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAE 1608 Query: 64 LLSENN--RLRMELETIKEKFEVQHS----------EGYRQISA--------LEDDLAQT 103 + S N+ RL+ ++E + E+Q + YR A L+D L Sbjct: 1609 IRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQ 1668 Query: 104 KAIKDQ----------LQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLE 153 + +K+Q LQ I EL + ER+++ L D +R+ +N L Sbjct: 1669 EDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSL- 1727 Query: 154 SELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188 ++ K+ L + +++ E D+ QE +++ K Sbjct: 1728 --INTKKKLETDISQIQGEMEDIIQEARNAEEKAK 1760 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.307 0.124 0.334 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,627,515 Number of Sequences: 37866 Number of extensions: 624546 Number of successful extensions: 8636 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 358 Number of HSP's successfully gapped in prelim test: 887 Number of HSP's that attempted gapping in prelim test: 4213 Number of HSP's gapped (non-prelim): 3822 length of query: 335 length of database: 18,247,518 effective HSP length: 103 effective length of query: 232 effective length of database: 14,347,320 effective search space: 3328578240 effective search space used: 3328578240 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.