Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 221316642

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|221316642 nuclear distribution gene E homolog 1 [Homo
sapiens]
         (335 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|221316642 nuclear distribution gene E homolog 1 [Homo sapiens]     654   0.0  
gi|8923110 nuclear distribution gene E homolog 1 [Homo sapiens]       654   0.0  
gi|13540600 nudE nuclear distribution gene E homolog (A. nidulan...   339   2e-93
gi|71284108 nudE nuclear distribution gene E homolog (A. nidulan...   339   2e-93
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    62   6e-10
gi|114155142 nuclear pore complex-associated protein TPR [Homo s...    60   4e-09
gi|31982906 cingulin-like 1 [Homo sapiens]                             59   5e-09
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                59   6e-09
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]     58   1e-08
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     56   4e-08
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa...    56   4e-08
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    56   5e-08
gi|41872583 Rho-associated, coiled-coil containing protein kinas...    55   9e-08
gi|32698688 citron [Homo sapiens]                                      55   9e-08
gi|34878904 synaptonemal complex protein 1 [Homo sapiens]              54   2e-07
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...    54   2e-07
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...    54   2e-07
gi|156104908 myosin heavy chain 6 [Homo sapiens]                       54   2e-07
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...    54   3e-07
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    53   3e-07
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    53   3e-07
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...    53   3e-07
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    53   3e-07
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    53   3e-07
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    53   3e-07
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    53   4e-07
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    53   4e-07
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    53   4e-07
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    53   4e-07
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...    53   4e-07

>gi|221316642 nuclear distribution gene E homolog 1 [Homo sapiens]
          Length = 335

 Score =  654 bits (1687), Expect = 0.0
 Identities = 335/335 (100%), Positives = 335/335 (100%)

Query: 1   MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
           MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR
Sbjct: 1   MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60

Query: 61  NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
           NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA
Sbjct: 61  NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120

Query: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
           NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL
Sbjct: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180

Query: 181 AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDST 240
           AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDST
Sbjct: 181 AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDST 240

Query: 241 GGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDG 300
           GGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDG
Sbjct: 241 GGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDG 300

Query: 301 GERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC 335
           GERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC
Sbjct: 301 GERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC 335


>gi|8923110 nuclear distribution gene E homolog 1 [Homo sapiens]
          Length = 335

 Score =  654 bits (1687), Expect = 0.0
 Identities = 335/335 (100%), Positives = 335/335 (100%)

Query: 1   MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
           MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR
Sbjct: 1   MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60

Query: 61  NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
           NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA
Sbjct: 61  NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120

Query: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
           NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL
Sbjct: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180

Query: 181 AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDST 240
           AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDST
Sbjct: 181 AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDST 240

Query: 241 GGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDG 300
           GGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDG
Sbjct: 241 GGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRTGGPASGRSSKNRDG 300

Query: 301 GERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC 335
           GERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC
Sbjct: 301 GERRPSSTSVPLGDKGLDTSCRWLSKSTTRSSSSC 335


>gi|13540600 nudE nuclear distribution gene E homolog (A.
           nidulans)-like 1 isoform B [Homo sapiens]
          Length = 345

 Score =  339 bits (870), Expect = 2e-93
 Identities = 181/282 (64%), Positives = 226/282 (80%), Gaps = 8/282 (2%)

Query: 8   FSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSE 67
           FSS +EE  YWK+L++ YKQ  +  ++EL EFQEGSRE EAELE QL Q E RNRDL ++
Sbjct: 9   FSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQAD 68

Query: 68  NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127
           N RL+ E+E +KEK E Q+++ Y+Q+S LEDDL+QT+AIK+QL KY+RELEQANDDLERA
Sbjct: 69  NQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERA 128

Query: 128 KRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQK-Q 186
           KRATI+SLEDFEQRLNQAIERNAFLESELDEKE+LL SVQRLKDEARDLRQELAV+++ Q
Sbjct: 129 KRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQ 188

Query: 187 EKPRTPMPSS--VEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDSTGGTP 244
           E  R   PSS  ++ E+ D+AVQA+ S+P+TP+  +G  ++  +P +   G     G +P
Sbjct: 189 EVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVG-KGTENTFPSPKAIPNGF----GTSP 243

Query: 245 LTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRT 286
           LTP+ARISALNIVGDLLRKVGALESKLA+CRN   DQ+  ++
Sbjct: 244 LTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKS 285


>gi|71284108 nudE nuclear distribution gene E homolog (A.
           nidulans)-like 1 isoform A [Homo sapiens]
          Length = 328

 Score =  339 bits (870), Expect = 2e-93
 Identities = 181/282 (64%), Positives = 226/282 (80%), Gaps = 8/282 (2%)

Query: 8   FSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSE 67
           FSS +EE  YWK+L++ YKQ  +  ++EL EFQEGSRE EAELE QL Q E RNRDL ++
Sbjct: 9   FSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQAD 68

Query: 68  NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127
           N RL+ E+E +KEK E Q+++ Y+Q+S LEDDL+QT+AIK+QL KY+RELEQANDDLERA
Sbjct: 69  NQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERA 128

Query: 128 KRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQK-Q 186
           KRATI+SLEDFEQRLNQAIERNAFLESELDEKE+LL SVQRLKDEARDLRQELAV+++ Q
Sbjct: 129 KRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQ 188

Query: 187 EKPRTPMPSS--VEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDSTGGTP 244
           E  R   PSS  ++ E+ D+AVQA+ S+P+TP+  +G  ++  +P +   G     G +P
Sbjct: 189 EVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVG-KGTENTFPSPKAIPNGF----GTSP 243

Query: 245 LTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRT 286
           LTP+ARISALNIVGDLLRKVGALESKLA+CRN   DQ+  ++
Sbjct: 244 LTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKS 285


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 50/197 (25%), Positives = 97/197 (49%), Gaps = 9/197 (4%)

Query: 12   EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSE---N 68
            EEE    +      +QR     EEL E  E ++ ++A LE   Q +ET N++L  E    
Sbjct: 1184 EEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVL 1243

Query: 69   NRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128
             +++ E E  ++K + Q  E + ++S  E D  + + + ++  K   EL+  +  LE A+
Sbjct: 1244 QQVKAESEHKRKKLDAQVQELHAKVS--EGDRLRVE-LAEKASKLQNELDNVSTLLEEAE 1300

Query: 129  RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
            +  I   +D     +Q  +    L+ E  +K NL   +++L++E   L+++   Q+++E+
Sbjct: 1301 KKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQ---QEEEEE 1357

Query: 189  PRTPMPSSVEAERTDTA 205
             R  +   V A ++  A
Sbjct: 1358 ARKNLEKQVLALQSQLA 1374



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 54/231 (23%), Positives = 94/231 (40%), Gaps = 52/231 (22%)

Query: 19   KDLAMTYKQRAENTQEELREFQ----------EGSREYEAELETQLQQIETRNRDLLSEN 68
            K ++  Y +  +  + E RE +          E + E + E E Q +Q+     DL+S  
Sbjct: 1461 KSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSK 1520

Query: 69   NRLRM---ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQ--------KYIREL 117
            + +     ELE  K   E Q  E   Q+  LED+L  T+  K +L+        ++ R+L
Sbjct: 1521 DDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDL 1580

Query: 118  EQANDDLERAKRATIMSLEDFEQRLNQAIERNAF-------LESELDEKENLLESVQRLK 170
            +  ++  E  KR  I  + + E  L    ++ A        +E +L + E  +E+  + +
Sbjct: 1581 QTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKAR 1640

Query: 171  DE---------------------ARDLRQELAVQQKQEKPRTPMPSSVEAE 200
            DE                     AR  R E+  Q K+ + +     S+EAE
Sbjct: 1641 DEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKL---KSLEAE 1688



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 44/177 (24%), Positives = 85/177 (48%), Gaps = 24/177 (13%)

Query: 29   AENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSE 88
            AE  +  L   ++   E   +LE+++++ E RN+ L +E  +++  ++ ++E  ++   E
Sbjct: 906  AEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEE--QLDEEE 963

Query: 89   GYRQISALEDDLAQTK---------AIKDQLQKYIRELEQANDDLERAKRATIMSLEDFE 139
            G RQ   LE   A+ K          ++DQ  K+I+E +   D   R    +    E+ E
Sbjct: 964  GARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMED---RIAECSSQLAEEEE 1020

Query: 140  QRLNQAIERN--AFLESELDE--------KENLLESVQRLKDEARDLRQELAVQQKQ 186
            +  N A  RN    + S+L+E        ++ L ++ ++L  E  DL+ ++A  Q Q
Sbjct: 1021 KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQ 1077



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 43/193 (22%), Positives = 81/193 (41%), Gaps = 13/193 (6%)

Query: 14   EANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRM 73
            + ++ + +A   +++ +   + L E +  S  Y  E +    +   +    LS    L  
Sbjct: 1435 DLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEE 1494

Query: 74   ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIM 133
             LE  KE+FE       RQ   L  D+    + KD + K + ELE++   LE+       
Sbjct: 1495 ALEA-KEEFE-------RQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRT 1546

Query: 134  SLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPM 193
             LE+ E  L    +    LE  +   +   E   + +DE  + ++ L ++Q +E     +
Sbjct: 1547 QLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRE-----L 1601

Query: 194  PSSVEAERTDTAV 206
             + +E ER   A+
Sbjct: 1602 EAELEDERKQRAL 1614



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 41/194 (21%), Positives = 88/194 (45%), Gaps = 14/194 (7%)

Query: 2    EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGS-----------REYEAEL 50
            +D GK     E+     +      + + E  ++EL+  ++              ++E +L
Sbjct: 1521 DDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDL 1580

Query: 51   ETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAI---K 107
            +T+ +Q E + R L+ +   L  ELE  +++  +  +   +    L+D  AQ +A    +
Sbjct: 1581 QTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKAR 1640

Query: 108  DQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQ 167
            D++ K +R+L+    D +R       S ++   +  ++ ++   LE+E+ + +  L S +
Sbjct: 1641 DEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSE 1700

Query: 168  RLKDEARDLRQELA 181
            R +  A   R ELA
Sbjct: 1701 RARRHAEQERDELA 1714



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 46/183 (25%), Positives = 82/183 (44%), Gaps = 21/183 (11%)

Query: 30   ENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEG 89
            E  +++  +F + +   E++L+   + ++   R  L+ ++R+R +LE  K   + Q  E 
Sbjct: 1297 EEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIR-QLEEEKNSLQEQQEEE 1355

Query: 90   Y-------RQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRL 142
                    +Q+ AL+  LA TK   D     I  LE+A   L          L+D E  L
Sbjct: 1356 EEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKL----------LKDAE-AL 1404

Query: 143  NQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEAERT 202
            +Q +E  A    +L++ +N L+  Q L D   DL  +  V    EK +      +  E++
Sbjct: 1405 SQRLEEKALAYDKLEKTKNRLQ--QELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKS 1462

Query: 203  DTA 205
             +A
Sbjct: 1463 ISA 1465



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 31/141 (21%), Positives = 65/141 (46%), Gaps = 32/141 (22%)

Query: 44  REYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQT 103
           +E + ++E +L+++E +++ LL E N L  +L+   E F                  A+ 
Sbjct: 865 KEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELF------------------AEA 906

Query: 104 KAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLL 163
           + ++ +L    +ELE+               L D E R+ +  ERN  L++E  + +  +
Sbjct: 907 EEMRARLAAKKQELEEI--------------LHDLESRVEEEEERNQILQNEKKKMQAHI 952

Query: 164 ESVQRLKDEARDLRQELAVQQ 184
           + ++   DE    RQ+L +++
Sbjct: 953 QDLEEQLDEEEGARQKLQLEK 973



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 36/195 (18%), Positives = 83/195 (42%), Gaps = 28/195 (14%)

Query: 27   QRAENTQEELREFQEGSREYEAELETQLQQIETRNRDL---LSENNRLRMELETIKEKFE 83
            +R +   E  +  +E ++ +EA+++   Q+  T   +L   L +  R +  LE  K+  E
Sbjct: 1171 KREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLE 1230

Query: 84   VQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLN 143
              + E   ++  L+   A+++  + +L   ++EL     + +R +               
Sbjct: 1231 TDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRV-------------- 1276

Query: 144  QAIERNAFLESELDEKENLLESVQR-----------LKDEARDLRQELAVQQKQEKPRTP 192
            +  E+ + L++ELD    LLE  ++           L+ + +D ++ L  + +Q+   + 
Sbjct: 1277 ELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSS 1336

Query: 193  MPSSVEAERTDTAVQ 207
                +E E+     Q
Sbjct: 1337 RIRQLEEEKNSLQEQ 1351



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 41/192 (21%), Positives = 89/192 (46%), Gaps = 19/192 (9%)

Query: 10   SEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69
            +E++   + KD A + + + ++TQE L   QE +R+ +  L ++++Q+E     L  +  
Sbjct: 1299 AEKKGIKFAKDAA-SLESQLQDTQELL---QEETRQ-KLNLSSRIRQLEEEKNSLQEQQE 1353

Query: 70   RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ---------- 119
                  + ++++     S+       ++DDL   +++++  +K +++ E           
Sbjct: 1354 EEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKAL 1413

Query: 120  ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLL---ESVQRLKDEARDL 176
            A D LE+ K      L+D    L+   +  + LE +  + + LL   +S+     E RD 
Sbjct: 1414 AYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERD- 1472

Query: 177  RQELAVQQKQEK 188
            R E   ++K+ K
Sbjct: 1473 RAEAEAREKETK 1484



 Score = 36.6 bits (83), Expect = 0.032
 Identities = 44/227 (19%), Positives = 97/227 (42%), Gaps = 49/227 (21%)

Query: 26   KQRAENTQEELREFQEGSREYEA---ELETQLQQIETRNRDLLSENNRLRMELETIKEKF 82
            + R E  +E  +  Q   ++ +A   +LE QL + E   + L  E      +++ ++E+ 
Sbjct: 928  ESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEI 987

Query: 83   ---EVQHSEGYRQISALEDDLAQTKA---------------------IKDQLQKYIRELE 118
               E Q+S+  ++   +ED +A+  +                     +   L++ +++ E
Sbjct: 988  LLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEE 1047

Query: 119  QANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKE------------------ 160
            +   +LE+AKR       D + ++ +   +   L+ +L +KE                  
Sbjct: 1048 KTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKN 1107

Query: 161  NLLESVQRLKDEARDLRQ----ELAVQQKQEKPRTPMPSSVEAERTD 203
            N L+ V+ L+ +  +L++    E A + K EK +  +   +EA +T+
Sbjct: 1108 NALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTE 1154



 Score = 36.2 bits (82), Expect = 0.042
 Identities = 41/204 (20%), Positives = 87/204 (42%), Gaps = 27/204 (13%)

Query: 9    SSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEA---ELETQLQQIETRNRDLL 65
            + EEE+A     +    +    + +E L++ ++  +E E    +L+ +   ++ +  +L 
Sbjct: 1016 AEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQ 1075

Query: 66   SENNRLRMELETIKEKFEVQHSEG-----------------YRQISALEDDLAQTKAIKD 108
            ++ + L+++L   +E+ +   + G                   QI+ L++D    KA ++
Sbjct: 1076 AQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRN 1135

Query: 109  QLQKYIR----ELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLE 164
            + +K  R    ELE    +LE     T    E   +R  +  E    LE   +E +N   
Sbjct: 1136 KAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALE---EETKNHEA 1192

Query: 165  SVQRLKDEARDLRQELAVQQKQEK 188
             +Q ++       +EL+ Q +Q K
Sbjct: 1193 QIQDMRQRHATALEELSEQLEQAK 1216



 Score = 35.4 bits (80), Expect = 0.072
 Identities = 46/218 (21%), Positives = 92/218 (42%), Gaps = 23/218 (10%)

Query: 12   EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL 71
            EE+A  +  L  T K R +   ++L    +  R+  + LE + ++ +     LL+E   +
Sbjct: 1409 EEKALAYDKLEKT-KNRLQQELDDLTVDLDHQRQVASNLEKKQKKFD----QLLAEEKSI 1463

Query: 72   RMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR-- 129
                   +++ E +  E   +  +L   L +    K++ ++  ++L    +DL  +K   
Sbjct: 1464 SARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDV 1523

Query: 130  -ATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQ----- 183
               +  LE  ++ L Q +E    + ++L+E E+ L++ +  K       Q +  Q     
Sbjct: 1524 GKNVHELEKSKRALEQQVEE---MRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDL 1580

Query: 184  -----QKQEKPRTPMPS--SVEAERTDTAVQATGSVPS 214
                 Q +EK R  +     +EAE  D   Q   +V S
Sbjct: 1581 QTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVAS 1618



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 45/197 (22%), Positives = 72/197 (36%), Gaps = 54/197 (27%)

Query: 28   RAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSE-----------------NNR 70
            R    +EEL E Q               Q++T N +L +E                 N  
Sbjct: 1737 RIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKE 1796

Query: 71   LRMELE----TIKEKFEVQHSEGYRQISALEDDLAQT---------------KAIKD--- 108
            L+ +L+     +K KF+   S    +I  LE+ L Q                K +K+   
Sbjct: 1797 LKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFM 1856

Query: 109  -------QLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDE--- 158
                      +Y  ++E+AN  +++ KR     LE+ E+   +A      L+ ELD+   
Sbjct: 1857 QVEDERRHADQYKEQMEKANARMKQLKR----QLEEAEEEATRANASRRKLQRELDDATE 1912

Query: 159  -KENLLESVQRLKDEAR 174
              E L   V  LK+  R
Sbjct: 1913 ANEGLSREVSTLKNRLR 1929


>gi|114155142 nuclear pore complex-associated protein TPR [Homo
            sapiens]
          Length = 2363

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 59/228 (25%), Positives = 106/228 (46%), Gaps = 20/228 (8%)

Query: 1    MEDSGKTFSSEEEE---ANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQI 57
            ME S ++    +E+       ++L  T  Q AE   + L    E  ++  +E ET+ + +
Sbjct: 1456 METSAQSSGDHQEQHVSVQEMQELKETLNQ-AETKSKSLESQVENLQKTLSEKETEARNL 1514

Query: 58   ETRNRDLLSENNRLRMEL-------ETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQL 110
            + +   L SE +RLR +L       E ++++   +  +  + I A +  +A    +KDQL
Sbjct: 1515 QEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQL 1574

Query: 111  QKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDE-KENLLESVQRL 169
             K   EL+Q N  L++ K    + +   + +    I R   LE EL E +E  LE     
Sbjct: 1575 TKENEELKQRNGALDQQKDELDVRITALKSQYEGRISR---LERELREHQERHLEQ---- 1627

Query: 170  KDEARDLRQELAVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPI 217
            +DE ++   ++  QQ+Q   +T  P+S E     T+   T ++  TP+
Sbjct: 1628 RDEPQEPSNKVPEQQRQITLKT-TPASGERGIASTSDPPTANIKPTPV 1674



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 48/205 (23%), Positives = 90/205 (43%), Gaps = 24/205 (11%)

Query: 25   YKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEV 84
            + +R +   EE+   +       A L      I++   DL    N++R E ETI++  + 
Sbjct: 1364 HTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDL----NKVRTEKETIQKDLDA 1419

Query: 85   QHSEGYRQISALEDDL-------AQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLED 137
            +  +   ++  +            Q + +K Q  K +    Q++ D  + +  ++  +++
Sbjct: 1420 KIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGD-HQEQHVSVQEMQE 1478

Query: 138  FEQRLNQAIERNAFLESE-------LDEKE----NLLESVQRLKDEARDLRQELAVQQKQ 186
             ++ LNQA  ++  LES+       L EKE    NL E   +L+ E   LRQ+L  +  Q
Sbjct: 1479 LKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQ 1538

Query: 187  EKPRTPMPSSVEAERTDTAVQATGS 211
            E+      +  E E+T  A+ A  S
Sbjct: 1539 EEQLRQQITEKE-EKTRKAIVAAKS 1562



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 46/227 (20%), Positives = 101/227 (44%), Gaps = 35/227 (15%)

Query: 20   DLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNR--------DLLSENNRL 71
            +L +  K+  +N Q+E+   ++     E ++ +Q  Q   + +        DL+S+  + 
Sbjct: 885  NLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQT 944

Query: 72   RMELETIKEKFEVQHS--EGYR-QISALEDDLAQTKAIKD------------------QL 110
              ++  +KE+ +   S  E Y+  +++LE+ L + K + +                  QL
Sbjct: 945  EEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQL 1004

Query: 111  QKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLK 170
            +K + E+E+   +L+  KR  I   E  EQ+L++  +  + +++E+ E      +    +
Sbjct: 1005 EKKLMEVEKEKQELQDDKRRAI---ESMEQQLSELKKTLSSVQNEVQEALQRASTALSNE 1061

Query: 171  DEARDLRQE---LAVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPS 214
             +AR   QE   +AV+ + +  R  M  + + E    A +    + S
Sbjct: 1062 QQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMAS 1108



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 43/172 (25%), Positives = 76/172 (44%), Gaps = 21/172 (12%)

Query: 22   AMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEK 81
            ++ Y+QR E  + EL+E Q+ S   E E      +   ++ +L+ +   + + +ET K  
Sbjct: 1221 SLRYRQRVELLERELQELQD-SLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKML 1279

Query: 82   FEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQR 141
             E +          LE DL Q +A   +L+  I  L++AN +L           +  E+ 
Sbjct: 1280 REEKER--------LEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEED 1331

Query: 142  LNQAIERNAFLESE------------LDEKENLLESVQRLKDEARDLRQELA 181
            + +   RN  L S+            L EKE   + +Q+L +E   L+ E+A
Sbjct: 1332 VKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIA 1383



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 49/219 (22%), Positives = 101/219 (46%), Gaps = 37/219 (16%)

Query: 22  AMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEK 81
           A+  K   +  QE    +++   E E     QL++++ +  DL S+N ++  +L+   ++
Sbjct: 665 AIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKR 724

Query: 82  FEV--QHSEGY-RQISALEDDLAQTKAIKDQLQKYI----RELEQANDDL-------ERA 127
           +E+   + EGY R+I++L +   +  A   + ++ I    ++L  AN+ L       E  
Sbjct: 725 YEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENL 784

Query: 128 KRATIMSLEDFEQRLNQAIE--------RNAFL-----------ESELDEKENLLESVQR 168
           K+   M L+  E RL+Q  E        +N  L            SE + K+ L   +++
Sbjct: 785 KKEKEM-LKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEK 843

Query: 169 LKDEARDLRQELAVQQKQEKPRTPMPSSVEAERTDTAVQ 207
           L+ E   L+++L   + + + R  +  +++ +  DT  Q
Sbjct: 844 LEHEISHLKKKL---ENEVEQRHTLTRNLDVQLLDTKRQ 879



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 44/162 (27%), Positives = 77/162 (47%), Gaps = 28/162 (17%)

Query: 34  EELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQI 93
           +EL   Q+ +   +++     +++E   RDL+  N RL  ELE + E            +
Sbjct: 97  KELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTE-----------DV 145

Query: 94  SALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIE----RN 149
             L + L ++   K +LQ  + EL QA+D          +S++  E+RL Q  E    +N
Sbjct: 146 KRLNEKLKESNTTKGELQLKLDEL-QASD----------VSVKYREKRLEQEKELLHSQN 194

Query: 150 AFLESELDEKENLLESVQRLK-DEARDLRQELAVQQKQEKPR 190
            +L +EL  K + L ++ R K +E  +L+  L   +K+E  R
Sbjct: 195 TWLNTELKTKTDELLALGREKGNEILELKCNLE-NKKEEVSR 235



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 33/145 (22%), Positives = 68/145 (46%), Gaps = 11/145 (7%)

Query: 35  ELREFQEGSREYEAELETQLQQIETRNR-------DLLSENNRLRMELETIKEKFEVQHS 87
           EL+   E  +E  + LE Q+  ++T N        DLL++    + +  +++EKF  + +
Sbjct: 221 ELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELN 280

Query: 88  EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQ--- 144
              +  +  +     ++A  ++L + + EL +   +   A +A    L + EQ  +Q   
Sbjct: 281 AHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEK 340

Query: 145 -AIERNAFLESELDEKENLLESVQR 168
             +E+   LE EL+   +LL + +R
Sbjct: 341 EMLEKIGRLEKELENANDLLSATKR 365



 Score = 36.6 bits (83), Expect = 0.032
 Identities = 44/189 (23%), Positives = 84/189 (44%), Gaps = 28/189 (14%)

Query: 7   TFSSEEEEANYWKDLAMTYK---QRAENTQEELREFQEGSREY---EAELETQLQQIET- 59
           T + EE EA   +DL  T +   Q  E   E+++   E  +E    + EL+ +L +++  
Sbjct: 114 TRTKEELEAEK-RDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQAS 172

Query: 60  ------------RNRDLL-SENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAI 106
                       + ++LL S+N  L  EL+T  ++      E   +I  L+ +L   K  
Sbjct: 173 DVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEE 232

Query: 107 KDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESV 166
             +L++ +  L+ +N+ L++        +ED   +L +A E+ A +E +   + N    +
Sbjct: 233 VSRLEEQMNGLKTSNEHLQK-------HVEDLLTKLKEAKEQQASMEEKFHNELNAHIKL 285

Query: 167 QRLKDEARD 175
             L   A D
Sbjct: 286 SNLYKSAAD 294



 Score = 36.6 bits (83), Expect = 0.032
 Identities = 37/188 (19%), Positives = 80/188 (42%), Gaps = 12/188 (6%)

Query: 1   MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGS---REYEAELETQLQQI 57
           +E        + EE    +    +   + E   +E++  QE +    +  + LE   +++
Sbjct: 430 VEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRM 489

Query: 58  ETRNRDLLSENNRLRMELETIKEKFEVQHSE-GYRQISALEDDLAQ-------TKAIKDQ 109
           E + +DL  +   L MELE  +    ++  E     IS+  + ++Q        + ++ Q
Sbjct: 490 EIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQ 549

Query: 110 LQKYIRELEQANDDLERAKRATIMS-LEDFEQRLNQAIERNAFLESELDEKENLLESVQR 168
            Q+ +  L +  +  ER ++ T  S + + + +L  A+     L      +  L++S+ R
Sbjct: 550 NQRLLVALRELGETREREEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVR 609

Query: 169 LKDEARDL 176
            +D  R L
Sbjct: 610 QRDMYRIL 617



 Score = 36.6 bits (83), Expect = 0.032
 Identities = 42/175 (24%), Positives = 72/175 (41%), Gaps = 14/175 (8%)

Query: 9    SSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSEN 68
            +S EE  N  K +    ++  E   +E  EFQ    +   E+E + Q+++   R  +   
Sbjct: 970  TSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESM 1029

Query: 69   NRLRMELETIKEKFEVQHSEGYRQIS--------ALEDDLAQTKAIKDQLQKYIRELEQA 120
             +   EL+      + +  E  ++ S        A  D   Q K   +   KY REL   
Sbjct: 1030 EQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLH 1089

Query: 121  NDDLE--RAKRATIMSLEDFEQRLNQAIERNAFLESELDE-KENLLESVQRLKDE 172
              D+E  +A +  +  +    Q L +  ++    ES+L E K +  E  + LKDE
Sbjct: 1090 AADVEALQAAKEQVSKMASVRQHLEETTQK---AESQLLECKASWEERERMLKDE 1141



 Score = 36.2 bits (82), Expect = 0.042
 Identities = 38/153 (24%), Positives = 68/153 (44%), Gaps = 8/153 (5%)

Query: 38  EFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALE 97
           +F+  S +   E+E +L   + R  +   E   LR+ELE +  + +   +E  +++   +
Sbjct: 45  KFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKAL-TEKNKELEIAQ 103

Query: 98  DDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLE---DFEQRLNQAIERNAFLES 154
           D   +  AI+ Q  +   ELE    DL R        LE   +  +RLN+ ++ +   + 
Sbjct: 104 D---RNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKG 160

Query: 155 ELDEK-ENLLESVQRLKDEARDLRQELAVQQKQ 186
           EL  K + L  S   +K   + L QE  +   Q
Sbjct: 161 ELQLKLDELQASDVSVKYREKRLEQEKELLHSQ 193



 Score = 32.7 bits (73), Expect = 0.47
 Identities = 34/133 (25%), Positives = 65/133 (48%), Gaps = 13/133 (9%)

Query: 55   QQIETRNRDLLSENNRLRMELETIK--EKFEVQHSEGYRQISALEDDLAQTKAIKDQLQK 112
            Q++E   R+L    + L  E E ++   K   QH E  ++   +   +   K ++++ ++
Sbjct: 1226 QRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKER 1285

Query: 113  YIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDE 172
              ++L+Q    + R     I+ L++    L+   E++  L++   EK+ L E V+R K  
Sbjct: 1286 LEQDLQQMQAKV-RKLELDILPLQEANAELS---EKSGMLQA---EKKLLEEDVKRWK-- 1336

Query: 173  ARDLRQELAVQQK 185
            AR+  Q L  QQK
Sbjct: 1337 ARN--QHLVSQQK 1347



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 28/159 (17%), Positives = 64/159 (40%), Gaps = 12/159 (7%)

Query: 40  QEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDD 99
           +    E +  L +Q++++E     L  +      +  T+    +VQ  +  RQ+    + 
Sbjct: 827 ERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNL 886

Query: 100 LAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEK 159
              TK +    QK I  L+Q   ++E      +       QR  +    N       ++ 
Sbjct: 887 HLNTKELLKNAQKEIATLKQHLSNME------VQVASQSSQRTGKGQPSNK------EDV 934

Query: 160 ENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVE 198
           ++L+  +++ +++  DL++ L       +    M +S+E
Sbjct: 935 DDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLE 973


>gi|31982906 cingulin-like 1 [Homo sapiens]
          Length = 1302

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 46/178 (25%), Positives = 82/178 (46%), Gaps = 4/178 (2%)

Query: 30   ENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEG 89
            E  Q+E+ +  E SR    EL+ QL + + +NR  L+E  R   E     EK  +   + 
Sbjct: 951  EKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKM 1010

Query: 90   YRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERN 149
              ++  +E++L   +  +D+     + LEQ   DLE    A     +D  + + Q  ++ 
Sbjct: 1011 QDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKV 1070

Query: 150  AFLESELDEKEN----LLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEAERTD 203
            + LE EL+E+ N    L E + R +++   LR EL  ++   +       S+E +  D
Sbjct: 1071 SQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQNKD 1128



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 61/228 (26%), Positives = 97/228 (42%), Gaps = 12/228 (5%)

Query: 1    MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
            MED       E EE     DL      R+    E+LR      R    +LE     +E +
Sbjct: 1066 MEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQ 1125

Query: 61   NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
            N+DL S    L     + KE   VQ      +I+ LED L   +  +  LQ   R LE+ 
Sbjct: 1126 NKDLKSRIIHLEGSYRSSKEGLVVQME---ARIAELEDRLESEERDRANLQLSNRRLERK 1182

Query: 121  NDDLERAKRATIMSLEDFEQRLN---QAIERNA-FLESELDEKENLLESVQRLKDEARDL 176
              +L        +SL D + +L+   +A++R     E E+D  E+  + +QR  +E  D+
Sbjct: 1183 VKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDM 1242

Query: 177  RQELAVQ---QKQEKPRTPMPSSVEAERTDTAVQAT--GSVPSTPIAH 219
             + L  Q    K++     +PS V  +  D    +T  GS+   P+++
Sbjct: 1243 NEHLQGQLNSMKKDLRLKKLPSKVLDDMDDDDDLSTDGGSLYEAPVSY 1290



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 45/181 (24%), Positives = 91/181 (50%), Gaps = 19/181 (10%)

Query: 28  RAENTQEELREFQEGSREYE---AELETQLQQIETRNRDLLSENNRLRMELETIKEKFEV 84
           +A N+  E+++  E   +     AEL+ QLQ      +++  E  R+R  LE ++     
Sbjct: 601 QACNSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRS---- 656

Query: 85  QHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQ 144
           QH+E   + S L+  L +++    +L+K + EL Q    +ER +  T   + D + +L++
Sbjct: 657 QHNEKVEENSTLQQRLEESEG---ELRKNLEELFQVK--MEREQHQT--EIRDLQDQLSE 709

Query: 145 A-IERNAFLESELDEKENLLESVQRLKDEARDL----RQELAVQQKQEKPRTPMPSSVEA 199
              E ++   SE  EK  L+E + + K + +DL     ++  + +K+E+  T +  +++ 
Sbjct: 710 MHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKE 769

Query: 200 E 200
           E
Sbjct: 770 E 770



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 50/193 (25%), Positives = 83/193 (43%), Gaps = 25/193 (12%)

Query: 30  ENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRM------ELETIKEKFE 83
           E    EL+  +E   E    +E    +  T  +D      R+++      +L+   E+ E
Sbjct: 783 EQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELE 842

Query: 84  VQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA-------NDDLERAKRATIMSLE 136
            + ++  RQI  L+ D A+ K    + +  IR+LE+A         +   A+RA    LE
Sbjct: 843 RRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELE 902

Query: 137 DFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ-----EKPRT 191
             +  L+Q  +    L  +L E     ES Q  K++ R L+ E+  ++       EK + 
Sbjct: 903 AAQGNLSQTTQEQKQLSEKLKE-----ESEQ--KEQLRRLKNEMENERWHLGKTIEKLQK 955

Query: 192 PMPSSVEAERTDT 204
            M   VEA RT T
Sbjct: 956 EMADIVEASRTST 968



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 38/174 (21%), Positives = 79/174 (45%), Gaps = 2/174 (1%)

Query: 40  QEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDD 99
           Q+  +E    +   L+++ +++ + + EN+ L+  LE  + +      E ++     E  
Sbjct: 637 QQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQH 696

Query: 100 LAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEK 159
             + + ++DQL +   EL+ A    +R K A I  L   +Q L   +      E  L ++
Sbjct: 697 QTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKR 756

Query: 160 ENLLESVQ-RLKDEARDLRQEL-AVQQKQEKPRTPMPSSVEAERTDTAVQATGS 211
           E  L +++  LK+E     QE+  ++++ +     +  SVE    +  V A+ S
Sbjct: 757 ERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRS 810



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 39/184 (21%), Positives = 81/184 (44%), Gaps = 6/184 (3%)

Query: 26  KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
           ++R     EELR       E  + L+ +L++ E   R  L E  +++ME    +E+ + +
Sbjct: 644 RERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKME----REQHQTE 699

Query: 86  HSEGYRQISALEDDLAQTKAIKDQLQ-KYIRELEQANDDLERAKRATIMSLEDFEQRLNQ 144
             +   Q+S + D+L   K  +D+ +   I EL QA  DL+    A     +   +R  +
Sbjct: 700 IRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERE 759

Query: 145 AIERNAFLESELDEKENLLESVQRLKD-EARDLRQELAVQQKQEKPRTPMPSSVEAERTD 203
                  L+ E+   +  ++ ++   D E + LR+ +    K  +      ++ E ++  
Sbjct: 760 LTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAG 819

Query: 204 TAVQ 207
           T ++
Sbjct: 820 TEMR 823



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 44/198 (22%), Positives = 85/198 (42%), Gaps = 43/198 (21%)

Query: 1    MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
            M+D  +    E  +    +D A+T +Q  E T ++L        EYE E ++ L+     
Sbjct: 1010 MQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDL--------EYELEAKSHLKD---- 1057

Query: 61   NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
                  + +RL  ++E    + E++  E       L + +++++   +QL+  + +   A
Sbjct: 1058 ------DRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAA 1111

Query: 121  NDDLERAK----------RATIMSLE------------DFEQRLNQAIERNAFLESELDE 158
              DLE  K          ++ I+ LE              E R+ +  +R   LESE  +
Sbjct: 1112 RQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDR---LESEERD 1168

Query: 159  KENLLESVQRLKDEARDL 176
            + NL  S +RL+ + ++L
Sbjct: 1169 RANLQLSNRRLERKVKEL 1186



 Score = 33.5 bits (75), Expect = 0.27
 Identities = 31/171 (18%), Positives = 71/171 (41%), Gaps = 4/171 (2%)

Query: 34  EELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQI 93
           EEL + ++  ++     E Q   +  R R+L +    L+ E+ +  ++ +    +   ++
Sbjct: 730 EELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAEL 789

Query: 94  SALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLE 153
            AL + + +     + L       EQ     E   +      E  + R  +   R A L+
Sbjct: 790 QALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQ 849

Query: 154 SELD----EKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEAE 200
            +++    ++    E++++ + E R L + L   +K+EK       ++E E
Sbjct: 850 RQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENE 900


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 54/231 (23%), Positives = 96/231 (41%), Gaps = 20/231 (8%)

Query: 2   EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRN 61
           +D  +    +EE+A   + L    +++    QE L+ ++   R+   E E + ++ E R 
Sbjct: 427 KDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERR 486

Query: 62  RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQ-LQKYIRELEQA 120
           R++  E  RL+  LE                    +DD    K  +   LQK +R+ E+ 
Sbjct: 487 REMAKEAKRLKEFLEDY------------------DDDRDDPKYYRGSALQKRLRDREKE 528

Query: 121 NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
            +  ER ++     LE+  QRL      +   E +  E+E       ++K E     +E 
Sbjct: 529 MEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEE 588

Query: 181 AVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTP-IAHRGPSSSLNTPG 230
             Q+K+EK   PM    E E+          + S P ++    +++ NTPG
Sbjct: 589 EKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPG 639



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 55/229 (24%), Positives = 99/229 (43%), Gaps = 23/229 (10%)

Query: 11  EEEEANYWKDLAMTYKQRAENTQEELREFQ--------EGSREYEAELETQLQQIETRNR 62
           EEE+    K+     K+R E  +E  RE +        E  RE E E E + ++   R+R
Sbjct: 292 EEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDR 351

Query: 63  DLLSENNRLR---MELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ 119
           D   E +R R    + +  +E+   ++ +  R      D   + +  +++ ++  RE E+
Sbjct: 352 DRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERER 411

Query: 120 AND---DLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKD----E 172
             +   + ER +        D E+    A ER   LE +L EKE   +  +RLK+    E
Sbjct: 412 EREREREREREREREKDKKRDREEDEEDAYERRK-LERKLREKEAAYQ--ERLKNWEIRE 468

Query: 173 ARDLRQELAVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRG 221
            +  R+     +++E+ R  M  + EA+R    ++        P  +RG
Sbjct: 469 RKKTREYEKEAEREEERRREM--AKEAKRLKEFLEDYDDDRDDPKYYRG 515


>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
          Length = 1979

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 42/171 (24%), Positives = 92/171 (53%), Gaps = 21/171 (12%)

Query: 26  KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLS---ENNRLRMELETIKEK- 81
           K+R+   QEEL ++ +  R+ E   +T    IE ++R L S   ENN L+ ELE ++E+ 
Sbjct: 821 KERSSKLQEELDKYSQALRKNEILRQT----IEEKDRSLGSMKEENNHLQEELERLREEQ 876

Query: 82  ---FEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDF 138
                V   +    ++ L  +++Q   IK+ L++ I+  ++  +D  ++K   + SL++ 
Sbjct: 877 SRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQ 936

Query: 139 EQRLNQ---------AIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
           ++ +++         A     FLE + +E ++L ++++++K +  + RQ++
Sbjct: 937 KKEMDEFRYQHEQMNATHTQLFLEKD-EEIKSLQKTIEQIKTQLHEERQDI 986



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 28/130 (21%), Positives = 61/130 (46%), Gaps = 2/130 (1%)

Query: 11   EEEEANYWKD-LAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69
            E +E  Y  + +  T+ Q      EE++  Q+   + + +L  + Q I+T N D+  E  
Sbjct: 939  EMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETK 998

Query: 70   RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR 129
               + +E   EK ++  +E  R +  +++   + K + ++     ++++Q + D E  K 
Sbjct: 999  VQSLNIENGSEKHDLSKAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKD-EVGKL 1057

Query: 130  ATIMSLEDFE 139
              I+  +D E
Sbjct: 1058 TQIIQQKDLE 1067



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 41/204 (20%), Positives = 92/204 (45%), Gaps = 16/204 (7%)

Query: 6    KTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLL 65
            +T+  +E E    ++  M +       + E    +E +  +E       Q ++ + +   
Sbjct: 1470 ETYRGKETEYQALQETNMKFSMMLREKEFECHSMKEKALAFE-------QLLKEKEQGKT 1522

Query: 66   SENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLE 125
             E N+L   +++++EK  V   E  + + AL+    +  A+++++Q+   +  ++N +LE
Sbjct: 1523 GELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKEFRSNQELE 1582

Query: 126  RAKRATIMSLEDFEQRLNQAIERNA-------FLESELDEKENLLESV-QRLKDEARDLR 177
            R +   + S + + +    A +R A        LE +L    N +E+   +   +   L+
Sbjct: 1583 RLRNHLLESEDSYTREALAAEDREAKLRKKVTVLEEKLVSSSNAMENASHQASVQVESLQ 1642

Query: 178  QELAVQQKQEKPRTPMPSSVEAER 201
            ++L V  KQ +  T +  SV  E+
Sbjct: 1643 EQLNVVSKQ-RDETALQLSVSQEQ 1665



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 39/163 (23%), Positives = 81/163 (49%), Gaps = 4/163 (2%)

Query: 20  DLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIK 79
           DL +  + + +   + + E +    E E EL+ Q Q+       +  + ++ + E ++I 
Sbjct: 471 DLRLNLEAKEQELNQSISEKETLIAEIE-ELDRQNQEATKHMILIKDQLSKQQNEGDSII 529

Query: 80  EKFEVQHSEGYRQISALEDD-LAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDF 138
            K +   ++  +++  LEDD +  TK +  Q +K I+  E A +DL   K+     +E+ 
Sbjct: 530 SKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQS-EVALNDLHLTKQKLEDKVENL 588

Query: 139 EQRLNQAIERNAFLESE-LDEKENLLESVQRLKDEARDLRQEL 180
             +LN++ E N  ++ E L+ KE++ ++ + L     +L Q L
Sbjct: 589 VDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSL 631



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 33/161 (20%), Positives = 73/161 (45%), Gaps = 18/161 (11%)

Query: 34  EELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQI 93
           EE  ++++   E           ++  +  L+  N +  ME+  +K+  E   ++     
Sbjct: 734 EEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETK 793

Query: 94  SALEDDLAQTKAIKDQLQK---YIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNA 150
             L   L + K +   + K   +I +L++ +  L+          E+ + + +QA+ +N 
Sbjct: 794 DVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQ----------EELD-KYSQALRKNE 842

Query: 151 FLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRT 191
            L   ++EK+  L S   +K+E   L++EL  + ++E+ RT
Sbjct: 843 ILRQTIEEKDRSLGS---MKEENNHLQEELE-RLREEQSRT 879



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 30/88 (34%), Positives = 48/88 (54%), Gaps = 8/88 (9%)

Query: 41  EGSREYEAEL-ETQLQQIETRNRDLLSENNRLRMELETIKEKFEV------QHSEGYR-Q 92
           EG+ E EAEL +++ ++IE  +  L SEN RL+     ++EK E       Q S  YR Q
Sbjct: 40  EGTEEVEAELPDSRTKEIEAIHAILRSENERLKKLCTDLEEKHEASEIQIKQQSTSYRNQ 99

Query: 93  ISALEDDLAQTKAIKDQLQKYIRELEQA 120
           +   E +++  KA +  LQ  + +L+ A
Sbjct: 100 LQQKEVEISHLKARQIALQDQLLKLQSA 127



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 44/170 (25%), Positives = 76/170 (44%), Gaps = 26/170 (15%)

Query: 34  EELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQI 93
           +E  E Q    +   E E  ++   TR+  L SE + LR+ LE  +++     SE    I
Sbjct: 436 QEKEELQMSLLKLNNEYEV-IKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLI 494

Query: 94  SALEDDLAQTK-------AIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAI 146
           + +E+   Q +        IKDQL K   E +     L++        L D ++R++Q  
Sbjct: 495 AEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQ-------DLNDEKKRVHQLE 547

Query: 147 ERNAFLESELD-EKENLLES----------VQRLKDEARDLRQELAVQQK 185
           +    +  ELD +KE L++S           Q+L+D+  +L  +L   Q+
Sbjct: 548 DDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQE 597



 Score = 35.4 bits (80), Expect = 0.072
 Identities = 41/160 (25%), Positives = 72/160 (45%), Gaps = 26/160 (16%)

Query: 34   EELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQI 93
            E L E  E  ++   EL   LQ+ +   R L   N+RL   +    E    +H +     
Sbjct: 1336 EVLSESSELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQ----- 1390

Query: 94   SALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSL-EDFEQRLN------QAI 146
               + ++ Q K  +D LQK ++E     D L +AK   ++S  E+F  ++N      QA+
Sbjct: 1391 --TDSEIKQLKEKQDVLQKLLKE----KDLLIKAKSDQLLSSNENFTNKVNENELLRQAV 1444

Query: 147  ----ERNAFLESEL----DEKENLLESVQRLKDEARDLRQ 178
                ER   LE ++     E E ++E+ +  + E + L++
Sbjct: 1445 TNLKERILILEMDIGKLKGENEKIVETYRGKETEYQALQE 1484



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 43/197 (21%), Positives = 79/197 (40%), Gaps = 38/197 (19%)

Query: 12  EEEANYWKDLAMTYKQRA--------------------ENTQEELREFQEGSREYEAELE 51
           E E  +W+ +A T K +                     +N  +E+ + Q      +   +
Sbjct: 185 ESEVGHWRHIAQTSKAQGTDNSDQSEICKLQNIIKELKQNRSQEIDDHQHEMSVLQNAHQ 244

Query: 52  TQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQ 111
            +L +I  R+R+ LS+      ELE + +    Q   G      +E DL++      ++Q
Sbjct: 245 QKLTEISRRHREELSDYEERIEELENLLQ----QGGSG-----VIETDLSKIY----EMQ 291

Query: 112 KYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELD----EKENLLESVQ 167
           K I+ L+    +  +        ++D  ++L+ A      L  E +    EK  ++E  +
Sbjct: 292 KTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECE 351

Query: 168 RLKDEARDLRQELAVQQ 184
            LK E   L Q  AV+Q
Sbjct: 352 NLKLECSKL-QPSAVKQ 367



 Score = 28.9 bits (63), Expect = 6.8
 Identities = 41/203 (20%), Positives = 87/203 (42%), Gaps = 34/203 (16%)

Query: 31   NTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIK----------E 80
            N  EEL + ++  ++   ++E   QQ+ T  +++  E+ +L+ EL  ++           
Sbjct: 1202 NQFEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVLVDSDNNS 1261

Query: 81   KFEVQHS---EGYRQ----ISALEDDLAQTKAIKDQL----QKYIRELEQANDDLERAKR 129
            K +V ++   + Y Q    +     +LAQ +    QL       + +L+  +  L  A  
Sbjct: 1262 KLQVDYTGLIQSYEQNETKLKNFGQELAQVQHSIGQLCNTKDLLLGKLDIISPQLSSASL 1321

Query: 130  ATIMSLEDFEQRLNQAI-ERNAFLESELDEKENLLE----SVQRLKDEARDLRQELAVQQ 184
             T  S E      ++ + E +  L+ EL+E    L+    +++ L++    L   +A   
Sbjct: 1322 LTPQSAECLRASKSEVLSESSELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATS 1381

Query: 185  KQEKPRTPMPSSVEAERTDTAVQ 207
            + E+         E E+TD+ ++
Sbjct: 1382 ELERK--------EHEQTDSEIK 1396


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 50/195 (25%), Positives = 87/195 (44%), Gaps = 28/195 (14%)

Query: 19   KDLAMTYKQRAENTQEELREFQ----------EGSREYEAELETQLQQIETRNRDLLSEN 68
            K ++  Y +  +  + E RE +          E + E +AELE   +Q  T   DL+S  
Sbjct: 1454 KTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSK 1513

Query: 69   NRLRM---ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQ--------KYIREL 117
            + +     ELE  K   E Q  E   Q+  LED+L  T+  K +L+        ++ R+L
Sbjct: 1514 DDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDL 1573

Query: 118  EQANDDLERAKRATIMS-------LEDFEQRLNQAIERNAFLESELDEKENLLESVQRLK 170
            +  ++  E  K+  +         LED  ++ + A+     LE +L + E  ++S  + +
Sbjct: 1574 QGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNR 1633

Query: 171  DEARDLRQELAVQQK 185
            DEA    ++L  Q K
Sbjct: 1634 DEAIKQLRKLQAQMK 1648



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 46/204 (22%), Positives = 92/204 (45%), Gaps = 6/204 (2%)

Query: 12   EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL 71
            EEEA   +      +Q+     EEL E  E ++  +A LE   Q +E    +L +E   L
Sbjct: 1177 EEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVL 1236

Query: 72   ---RMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128
               + + E  ++K E Q  E   Q+   E +  +T+ + D++ K   EL+     L ++ 
Sbjct: 1237 LQGKGDSEHKRKKVEAQLQE--LQVKFNEGERVRTE-LADKVTKLQVELDNVTGLLSQSD 1293

Query: 129  RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
              +    +DF    +Q  +    L+ E  +K +L   +++++DE    R++L  +++ + 
Sbjct: 1294 SKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKH 1353

Query: 189  PRTPMPSSVEAERTDTAVQATGSV 212
                  +++ A+  D   +   SV
Sbjct: 1354 NLEKQIATLHAQVADMKKKMEDSV 1377



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 49/207 (23%), Positives = 89/207 (42%), Gaps = 27/207 (13%)

Query: 1    MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
            +E   K F +E E+    KD         E ++  L +  E  +    ELE +LQ  E  
Sbjct: 1495 LERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATE-- 1552

Query: 61   NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
                     RL + L+ +K +FE       R +   ++   Q++  K QL + +RE+E  
Sbjct: 1553 -----DAKLRLEVNLQAMKAQFE-------RDLQGRDE---QSEEKKKQLVRQVREMEAE 1597

Query: 121  NDDLER-------AKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEA 173
             +D  +       A++   M L+D E  ++ A +       +L + +  ++   R  D+ 
Sbjct: 1598 LEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDT 1657

Query: 174  RDLRQELAVQQKQEKPRTPMPSSVEAE 200
            R  R+E+  Q K+ + +     S+EAE
Sbjct: 1658 RASREEILAQAKENEKKL---KSMEAE 1681



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 49/192 (25%), Positives = 81/192 (42%), Gaps = 16/192 (8%)

Query: 12   EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYE------AELETQLQQIETRNRDLL 65
            EEE    +D      +  +  ++ + EF     E E      A+L+ + + + T   + L
Sbjct: 977  EEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERL 1036

Query: 66   SENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLE 125
                + R ELE  + K E   ++   QI+ L+  +A+   +K QL K   EL+ A   +E
Sbjct: 1037 RREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAE---LKMQLAKKEEELQAALARVE 1093

Query: 126  RAKRATIMSLEDFEQRLNQAIERNAFLESEL-------DEKENLLESVQRLKDEARDLRQ 178
                   M+L+   +  +Q  E    LESE         +K +L E ++ LK E  D   
Sbjct: 1094 EEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLD 1153

Query: 179  ELAVQQKQEKPR 190
              A QQ+    R
Sbjct: 1154 STAAQQELRSKR 1165



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 45/194 (23%), Positives = 81/194 (41%), Gaps = 14/194 (7%)

Query: 2    EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIET-- 59
            +D GK+    E+     +      K + E  ++EL+  ++     E  L+    Q E   
Sbjct: 1514 DDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDL 1573

Query: 60   RNRDLLSENNRLRM-----ELETIKEKFEVQHSEGYRQISALEDDLAQTKAI-------K 107
            + RD  SE  + ++     E+E   E    Q S        LE DL   +A        +
Sbjct: 1574 QGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNR 1633

Query: 108  DQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQ 167
            D+  K +R+L+    D  R    T  S E+   +  +  ++   +E+E+ + +  L + +
Sbjct: 1634 DEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAE 1693

Query: 168  RLKDEARDLRQELA 181
            R K +A+  R ELA
Sbjct: 1694 RAKRQAQQERDELA 1707



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 42/201 (20%), Positives = 93/201 (46%), Gaps = 29/201 (14%)

Query: 26   KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEK---F 82
            ++R ++ Q E ++ Q+  +E    LE QL++ E+  + L  E      +L+ ++E+    
Sbjct: 928  EERCQHLQAEKKKMQQNIQE----LEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIIL 983

Query: 83   EVQHSEGYRQISALEDDLAQ---------------------TKAIKDQLQKYIRELEQAN 121
            E Q+ +  ++   LED +A+                      +A+   L++ +R  E+  
Sbjct: 984  EDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQR 1043

Query: 122  DDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLE-SVQRLKDEARDLRQEL 180
             +LE+ +R       D   ++ +   + A L+ +L +KE  L+ ++ R+++EA      L
Sbjct: 1044 QELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMAL 1103

Query: 181  AVQQKQEKPRTPMPSSVEAER 201
               ++ E   + +   +E+ER
Sbjct: 1104 KKIRELESQISELQEDLESER 1124



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 41/187 (21%), Positives = 81/187 (43%), Gaps = 8/187 (4%)

Query: 26   KQRAENTQEELREFQEGSR-EYEAELETQLQQIETRNRDLLSEN---NRLRMELETIKEK 81
            + +AE  + +L E  E  + E E  L++   Q E R++     N     L  E +T + +
Sbjct: 1127 RNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQ 1186

Query: 82   FEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQR 141
             +    +  + +  L + L QTK +K  L+K  + LE    +L    +  +    D E +
Sbjct: 1187 IQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHK 1246

Query: 142  LNQAIERNAFLESELDEKE----NLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSV 197
              +   +   L+ + +E E     L + V +L+ E  ++   L+    +    T   S++
Sbjct: 1247 RKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSAL 1306

Query: 198  EAERTDT 204
            E++  DT
Sbjct: 1307 ESQLQDT 1313



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 37/170 (21%), Positives = 81/170 (47%), Gaps = 10/170 (5%)

Query: 26   KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
            +Q  E T+ +L        +  AEL+ Q+ +++ +   L  +   L+  L  ++E+   +
Sbjct: 1043 RQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQ---LAKKEEELQAALARVEEEAAQK 1099

Query: 86   HS------EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFE 139
            +       E   QIS L++DL   +A +++ +K  R+L +  + L+     T+ S    +
Sbjct: 1100 NMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159

Query: 140  QRLNQAIERNAFLESELDEKENLLES-VQRLKDEARDLRQELAVQQKQEK 188
            +  ++  +    L+  L+E+    E+ +Q ++ +     +ELA Q +Q K
Sbjct: 1160 ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTK 1209



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 61/302 (20%), Positives = 119/302 (39%), Gaps = 29/302 (9%)

Query: 30   ENTQEELREFQEGSREYEAE---LETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQH 86
            E    + +E ++  +  EAE   L+ +L   E   R    E + L  E+     K  +  
Sbjct: 1662 EEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALAL 1721

Query: 87   SEGYR---QISALEDDLAQ----TKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFE 139
             E  R   +I+ LE++L +    T+ I D+L+K   +++Q N DL   +R+     E+  
Sbjct: 1722 EEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDL-NLERSHAQKNENAR 1780

Query: 140  QRLNQAIERNAFLESELDEKENLLE-----SVQRLKDEARDLRQELAVQQKQEKPRTPMP 194
            Q+L +   +N  L+ +L E E  ++     S+  L+ +   L ++L  + K+ +      
Sbjct: 1781 QQLER---QNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQV 1837

Query: 195  SSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDSTGGTPLTPAARISAL 254
               E +  D  +Q      +          +       +R L+++        A+R    
Sbjct: 1838 RRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQ 1897

Query: 255  NIVGDLLRKVGALESKLASCRNLVYDQS-----PNRTGGPASGRSSKNR-----DGGERR 304
              + D      A+  +++S +N +         P R     +G  S        DG E +
Sbjct: 1898 RELEDATETADAMNREVSSLKNKLRRGDLPFVVPRRMARKGAGDGSDEEVDGKADGAEAK 1957

Query: 305  PS 306
            P+
Sbjct: 1958 PA 1959



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 29/128 (22%), Positives = 65/128 (50%), Gaps = 8/128 (6%)

Query: 43  SREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQ 102
           SR+ E  +  + + ++ R + L +EN     E+ET++ +   +  +   Q+ A  +  A+
Sbjct: 841 SRQEEEMMAKEEELVKVREKQLAAENRLT--EMETLQSQLMAEKLQLQEQLQAETELCAE 898

Query: 103 TKAIKDQLQKYIRELEQANDDLE---RAKRATIMSLEDFEQRLNQAIERNAFLESELDEK 159
            + ++ +L    +ELE+   DLE     +      L+  ++++ Q I+    LE +L+E+
Sbjct: 899 AEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQE---LEEQLEEE 955

Query: 160 ENLLESVQ 167
           E+  + +Q
Sbjct: 956 ESARQKLQ 963



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 47/198 (23%), Positives = 83/198 (41%), Gaps = 19/198 (9%)

Query: 4    SGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRN-- 61
            +G    S+ + +   KD +    Q  ++TQE L+E        +  L T+L+Q+E     
Sbjct: 1286 TGLLSQSDSKSSKLTKDFSALESQ-LQDTQELLQE----ENRQKLSLSTKLKQVEDEKNS 1340

Query: 62   -RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ- 119
             R+ L E    +  LE        Q ++  +++      L   + +K +LQK +  L Q 
Sbjct: 1341 FREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQR 1400

Query: 120  ------ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLL---ESVQRLK 170
                  A D LE+ K      L+D    L+   +    LE +  + + LL   +++    
Sbjct: 1401 HEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKY 1460

Query: 171  DEARDLRQELAVQQKQEK 188
             E RD R E   ++K+ K
Sbjct: 1461 AEERD-RAEAEAREKETK 1477



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 43/194 (22%), Positives = 84/194 (43%), Gaps = 25/194 (12%)

Query: 14   EANYWKDLAMTYKQRAENTQEELREFQEGSREYEAE---LETQLQQIETRNRDL---LSE 67
            + ++ +  A   +++ +   + L E +  S +Y  E    E + ++ ET+   L   L E
Sbjct: 1428 DLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEE 1487

Query: 68   NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127
                + ELE + ++F  +          +ED ++     KD + K + ELE++   LE+ 
Sbjct: 1488 AMEQKAELERLNKQFRTE----------MEDLMSS----KDDVGKSVHELEKSKRALEQQ 1533

Query: 128  KRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQE 187
                   LE+ E  L    +    LE  L   +   E   + +DE  + +++  V+Q +E
Sbjct: 1534 VEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE 1593

Query: 188  KPRTPMPSSVEAER 201
                 M + +E ER
Sbjct: 1594 -----MEAELEDER 1602



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 52/206 (25%), Positives = 82/206 (39%), Gaps = 49/206 (23%)

Query: 21   LAMTYKQRAE----NTQEELREFQEGSREYEAELETQLQQIETRNRDL--------LSEN 68
            LA+  K+R E      +EEL E Q  +      L+    QI+  N DL         +EN
Sbjct: 1719 LALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNEN 1778

Query: 69   NRLRMELETIKEKFEVQHSEG-----YR-QISALEDDLAQT------------------- 103
             R ++E +  + K ++Q  EG     Y+  I+ALE  +AQ                    
Sbjct: 1779 ARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVR 1838

Query: 104  ---KAIKD---QLQKYIRELEQANDDLERAK---RATIMSLEDFEQRLNQAIERNAFLES 154
               K +KD   Q+    R  EQ  D  ++A    +     LE+ E+   +A      L+ 
Sbjct: 1839 RTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQR 1898

Query: 155  ELDEKENLLESVQRLKDEARDLRQEL 180
            EL   E+  E+   +  E   L+ +L
Sbjct: 1899 EL---EDATETADAMNREVSSLKNKL 1921



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 16/72 (22%), Positives = 34/72 (47%)

Query: 1    MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
            ++D  +     +++A+         K++ E  +EE +      R+ + ELE   +  +  
Sbjct: 1851 VDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAM 1910

Query: 61   NRDLLSENNRLR 72
            NR++ S  N+LR
Sbjct: 1911 NREVSSLKNKLR 1922


>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
           sapiens]
          Length = 631

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 77/337 (22%), Positives = 134/337 (39%), Gaps = 61/337 (18%)

Query: 12  EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL 71
           E + +  KDL    ++     Q E RE +  ++E E     QLQ+ + R    L      
Sbjct: 316 EGKTSLHKDLKQKRRE-----QREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEA 370

Query: 72  RMELETIKEKFEVQHSEGYRQIS-ALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRA 130
           + + E + ++ E +    +R++  ALE  L + +  +  +Q    E+E   ++  R +R 
Sbjct: 371 QRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQA---EMELKEEEAAR-QRQ 426

Query: 131 TIMSLEDFEQRLNQAIE---------------RNAFLESELDEKENLLE-------SVQR 168
            I  LE+ +QRL +A++               +   LE E ++ + L++        ++R
Sbjct: 427 RIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLKEEQERYIER 486

Query: 169 LKDEARDLRQELA-----VQQKQEKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPS 223
            + E  +L+QE+A     +QQ Q++      +   A+    A Q      ST + H    
Sbjct: 487 AQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEAAQRKLRQASTNVKHWNVQ 546

Query: 224 SSL----NTPGSFRRGLDDS-TGGTPLTPAARISALNIVGDLLRKVGALESKLASCRNLV 278
            +       PG  R     S +G  P   A R S+L                    R   
Sbjct: 547 MNRLMHPIEPGDKRPVTSSSFSGFQPPLLAHRDSSLK-------------------RLTR 587

Query: 279 YDQSPNRTGGPASGRSSKNRDGGERRPSSTSVPLGDK 315
           +    NRT  P S    K+ +GG+  P+  S P  DK
Sbjct: 588 WGSQGNRTPSPNSNEQQKSLNGGDEAPAPASTPQEDK 624


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 40/178 (22%), Positives = 87/178 (48%), Gaps = 9/178 (5%)

Query: 11  EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70
           +EEE    +      +++    +E LRE +   RE E ++  Q +++  + ++L  +   
Sbjct: 277 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKE 336

Query: 71  LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRA 130
           LR + E  +++ ++Q  E        E    Q + +++Q +K  R+ E+  +  E+  R 
Sbjct: 337 LREQKELREQEEQMQEQE--------EKMWEQEEKMREQEEKMWRQEERLWEQ-EKQMRE 387

Query: 131 TIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
               + D E+R+ +  ER    E  + E+E + E V+++++E +   QE   + ++EK
Sbjct: 388 QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 31/180 (17%), Positives = 91/180 (50%), Gaps = 10/180 (5%)

Query: 10  SEEEEANYW-KDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSEN 68
           ++E+E   W ++  M  ++R    ++++RE +E  RE E +++ Q ++++ +   +  + 
Sbjct: 571 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE 630

Query: 69  NRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128
            +++ + E + E+ E    +        E+ + + + + +Q +K     +    +  + +
Sbjct: 631 EKMQEQEEKMWEQEEKMWEQ--------EEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQ 682

Query: 129 RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
              I   E  E++  Q  E+  + + ++ E+E++ E  +++++E   +R++    Q+QE+
Sbjct: 683 EEKIWEQEKMEKK-TQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEE 741



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 41/191 (21%), Positives = 92/191 (48%), Gaps = 20/191 (10%)

Query: 2   EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRN 61
           E  GK     E+E   W+      ++R    ++ELRE ++  RE + EL  Q +Q++ + 
Sbjct: 304 EQEGKM---REQEEKMWRQ-----EKRLREQEKELREQEKELRE-QKELREQEEQMQEQE 354

Query: 62  RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQAN 121
             +  +  ++R +    +EK   Q    + Q   + +   Q + ++DQ ++   + E+  
Sbjct: 355 EKMWEQEEKMREQ----EEKMWRQEERLWEQEKQMRE---QEQKMRDQEERMWEQDERLR 407

Query: 122 DDLERAKRATIM--SLEDF--EQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLR 177
           +  ER +    M   +E    E+++ +  ++    E ++ E+E + E  +++++E   +R
Sbjct: 408 EKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMR 467

Query: 178 QELAVQQKQEK 188
           ++    QKQE+
Sbjct: 468 EQEEKMQKQEE 478



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 36/195 (18%), Positives = 95/195 (48%), Gaps = 9/195 (4%)

Query: 1   MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
           M++  +    +EE+    ++     ++R    ++++RE ++  R+ E  +  Q +++  +
Sbjct: 350 MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 409

Query: 61  NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
             + + E  ++  ++E ++E+ ++Q  E  ++    E+ + + + I+++ +K   E E  
Sbjct: 410 -EERMREQEKMWEQVEKMREEKKMQEQE--KKTRDQEEKMQEEERIREREKKMREEEETM 466

Query: 121 NDDLERAKRATIMSLEDFE-----QRLNQAIERNAFLESELDEKENLLESVQRLKDEARD 175
            +  E+ ++      E  E     QRL +  E+    E   +++E + E  ++++D+   
Sbjct: 467 REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 526

Query: 176 LRQELAVQQKQEKPR 190
             QE  +  +QEK R
Sbjct: 527 WGQEKKM-WRQEKMR 540



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 39/184 (21%), Positives = 86/184 (46%), Gaps = 6/184 (3%)

Query: 11  EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQI-ETRNRDLLSENN 69
           E+E+    ++  M  ++R    ++++RE +E  RE E +++ Q + + E   ++   +  
Sbjct: 434 EQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL 493

Query: 70  RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQL-QKYIRELEQANDDLERAK 128
             + E    +EK + Q  + + Q   + D        K    Q+ +RE E    + E   
Sbjct: 494 PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 553

Query: 129 RATIMSLEDFEQRLN---QAIERNAF-LESELDEKENLLESVQRLKDEARDLRQELAVQQ 184
           R     + D E+R+    Q  E+  +  E ++ E+E + E  +++++E   +R++    Q
Sbjct: 554 RDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQ 613

Query: 185 KQEK 188
           +QE+
Sbjct: 614 EQEE 617



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 32/185 (17%), Positives = 85/185 (45%), Gaps = 6/185 (3%)

Query: 10  SEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69
           ++E+E   W    M  ++     ++++RE +E  RE E +++ Q ++++ +  ++  +  
Sbjct: 696 TQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEE 755

Query: 70  RLRMELETIKEKFEVQHSE----GYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLE 125
           ++  + E + E+  +   +     + ++   E    Q + ++DQ +K   + E+     E
Sbjct: 756 KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEE 815

Query: 126 RAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQK 185
           + +          E+   Q  +     E    ++E + E +Q  +++ R+  QE  ++ +
Sbjct: 816 KMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMRE--QEEKMRGQ 873

Query: 186 QEKPR 190
           +EK R
Sbjct: 874 EEKMR 878



 Score = 35.4 bits (80), Expect = 0.072
 Identities = 37/187 (19%), Positives = 86/187 (45%), Gaps = 25/187 (13%)

Query: 12  EEEANYWKDLAM------TYKQRAENTQEELREFQEGSREYE-AELETQLQQIETRNRDL 64
           E+E   W+   +       ++      QE+++E +E   E E  E +TQ Q+ +T +++ 
Sbjct: 649 EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEK 708

Query: 65  LSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL 124
           + E   +R   + ++E+ E+   +  +     E    Q + + +Q +K   + E+  +  
Sbjct: 709 MREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWE-- 766

Query: 125 ERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLR-QELAVQ 183
                         +QRL +  E+  +   ++ E+E + E  ++++D+   +R QE  ++
Sbjct: 767 --------------QQRLPEQKEK-LWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMR 811

Query: 184 QKQEKPR 190
            ++EK R
Sbjct: 812 GQEEKMR 818



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 40/180 (22%), Positives = 82/180 (45%), Gaps = 16/180 (8%)

Query: 13  EEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLR 72
           EE    +D       R   T EEL++         AEL+ +L   E       SE + ++
Sbjct: 200 EELTKERDALSLELYRNTITNEELKK-------KNAELQEKLPLAE-------SEKSEIQ 245

Query: 73  MELETIKEKFE-VQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRAT 131
           + ++ +K K E  +      Q + L++++ + +    + +K IR+ E+     E   R  
Sbjct: 246 LNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQ 305

Query: 132 IMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLR-QELAVQQKQEKPR 190
              + + E+++ +  +R    E EL E+E  L   + L+++   ++ QE  + +++EK R
Sbjct: 306 EGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMR 365


>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
           [Homo sapiens]
          Length = 1388

 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 56/222 (25%), Positives = 97/222 (43%), Gaps = 46/222 (20%)

Query: 12  EEEANYWKDLAMTYKQRAENTQ---EELREFQEGS-----------------REYEAELE 51
           E + N  KD     K+R +N+Q   E++ + Q                    R+ +AE  
Sbjct: 530 ENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESS 589

Query: 52  TQLQQIETRNRDL-----LSENNRLRMELETIKEKFEVQHSEGYR------------QIS 94
            Q+QQ+E+ NRDL     L E  +L++E E I  +  ++     R            +I 
Sbjct: 590 KQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRIC 649

Query: 95  ALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR----ATIMSLEDFEQRLNQAIERNA 150
            LE+DL   K +  +++   R+L++   DLE+ K          L+  +Q L Q    + 
Sbjct: 650 GLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHK 709

Query: 151 FLESELDEKENLLESVQRLKDEA-----RDLRQELAVQQKQE 187
             ++ L +K  + ES++  K EA     + L +E  ++QK E
Sbjct: 710 ATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVE 751



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 46/191 (24%), Positives = 84/191 (43%), Gaps = 18/191 (9%)

Query: 7    TFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQ-------IET 59
            T    E++     +  M  K   E    ELR+ ++ +     EL+ QL+         +T
Sbjct: 819  TLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKT 878

Query: 60   RNRDL---LSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRE 116
            + R+L     E  +L  EL+  K++ + +     R   A + ++  TKA  +QL + I  
Sbjct: 879  QVRELKEECEEKTKLGKELQQKKQELQDE-----RDSLAAQLEITLTKADSEQLARSI-- 931

Query: 117  LEQANDDLERAKRATIMSLEDFEQRLNQAI-ERNAFLESELDEKENLLESVQRLKDEARD 175
             E+   DLE+ K    + +++   R  Q + E++A + S  +    L   V  L +E  +
Sbjct: 932  AEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEE 991

Query: 176  LRQELAVQQKQ 186
            L  +L   Q+Q
Sbjct: 992  LNNKLKDVQEQ 1002



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 40/167 (23%), Positives = 79/167 (47%), Gaps = 29/167 (17%)

Query: 26   KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
            +Q A+   +EL++  E  + +    +TQ++++    ++   E  +L  EL+  K++ + +
Sbjct: 852  RQDADGQMKELQDQLEAEQYFSTLYKTQVREL----KEECEEKTKLGKELQQKKQELQDE 907

Query: 86   HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA------------------ 127
                 R   A + ++  TKA  +QL + I E + ++ + E+                   
Sbjct: 908  -----RDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELT 962

Query: 128  -KRATIMSLEDFEQRLNQAIERNAFLESELDEK-ENLLESVQRLKDE 172
             K ATI SLE+  + L   +   A  + EL+ K +++ E + RLKDE
Sbjct: 963  EKDATIASLEETNRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDE 1009



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 32/120 (26%), Positives = 58/120 (48%), Gaps = 6/120 (5%)

Query: 62  RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQAN 121
           R+  S  +R   E + I++K          ++ A E+   + K++  +L+K  +ELE+  
Sbjct: 429 RETDSIQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEE-E 487

Query: 122 DDLERAKRATIMSLEDFE---QRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQ 178
             L ++  + +  LE  +   Q  N   +R A  + E D+K NL   V  LKD+  DL++
Sbjct: 488 ITLRKSVESALRQLEREKALLQHKNAEYQRKA--DHEADKKRNLENDVNSLKDQLEDLKK 545



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 11/157 (7%)

Query: 35   ELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQIS 94
            E++E     ++   E +  +  +E  NR L S+   L  E E +  K +    +   Q+S
Sbjct: 949  EIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLK----DVQEQLS 1004

Query: 95   ALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIER-----N 149
             L+D+     AIK Q +K +   E+        K A IM+ ++  +R N    R     N
Sbjct: 1005 RLKDEEISAAAIKAQFEKQLL-TERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKEN 1063

Query: 150  AFLESEL-DEKENLLESVQRLKDEARDLRQELAVQQK 185
              L  EL  E+E L + + + + E  +++ ++A + +
Sbjct: 1064 RKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQ 1100



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 39/188 (20%), Positives = 83/188 (44%), Gaps = 9/188 (4%)

Query: 20  DLAMTYKQ--RAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELET 77
           DL M  +Q    + ++++L++      E +  LE Q  ++    +D   +   L+ +LE 
Sbjct: 809 DLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEA 868

Query: 78  IKEKFEVQHSEGYR-QISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLE 136
                E   S  Y+ Q+  L+++  +   +  +LQ+  +EL+   D L      T+   +
Sbjct: 869 -----EQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKAD 923

Query: 137 DFEQRLNQAIERNAFLESELDEKE-NLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPS 195
             +   + A E+ + LE E   KE  + E + R K E  +    +A  ++  +  T   +
Sbjct: 924 SEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVA 983

Query: 196 SVEAERTD 203
           ++  E+ +
Sbjct: 984 NLANEKEE 991



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 16/62 (25%), Positives = 36/62 (58%), Gaps = 3/62 (4%)

Query: 67   ENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLER 126
            EN +L MEL++ +EK   Q  +  ++++ ++  +A+   I+ +LQ     L+  + D+E+
Sbjct: 1062 ENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQ---MTLDSKDSDIEQ 1118

Query: 127  AK 128
             +
Sbjct: 1119 LR 1120


>gi|32698688 citron [Homo sapiens]
          Length = 2027

 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 50/203 (24%), Positives = 94/203 (46%), Gaps = 30/203 (14%)

Query: 24   TYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFE 83
            T   + E    +L E  E     +   + +L ++ETR R++  E+   ++EL+    + +
Sbjct: 821  TQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQ 880

Query: 84   VQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA--------------NDDLER--- 126
            +   E   Q++AL+   A   A++ QL++   ELE+                D+++R   
Sbjct: 881  LSLQERESQLTALQ---AARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFD 937

Query: 127  AKRATIMSLEDFEQRLNQAIERNA-------FLESELDEKENLLESVQRLKDEARDLRQE 179
            A R +   + D E++LNQ  E NA       +L  +LDE     + + +L+ E   LR+E
Sbjct: 938  ALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRRE 997

Query: 180  LAVQQKQEKPRTPMPSSVEAERT 202
            +    ++E   T    ++EA +T
Sbjct: 998  IT---EREMQLTSQKQTMEALKT 1017



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 28/135 (20%), Positives = 65/135 (48%), Gaps = 3/135 (2%)

Query: 29  AENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSE 88
           AE  +E+ RE Q  ++  E  L+ + Q  E + + L ++  +   + ET++   +    E
Sbjct: 693 AEELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEE 752

Query: 89  GYRQISALEDDLAQTKAIKDQ---LQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQA 145
            + +   L +  A   A+  +   L++ I EL +AN     +   T  +++  E+ +++ 
Sbjct: 753 AHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISEL 812

Query: 146 IERNAFLESELDEKE 160
            ++  +LE++  + E
Sbjct: 813 RQQKFYLETQAGKLE 827



 Score = 37.0 bits (84), Expect = 0.025
 Identities = 53/214 (24%), Positives = 84/214 (39%), Gaps = 27/214 (12%)

Query: 26   KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
            KQR    Q +L++  +  + +   L   LQ+   R   L +E + L  +LE I+  +  +
Sbjct: 1149 KQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHE 1208

Query: 86   HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQA 145
              +    IS       QTK I         +  QA  D    K+  + S    +  L   
Sbjct: 1209 KVKMEGTIS------QQTKLI---------DFLQAKMDQPAKKKKGLFSRRKEDPALPTQ 1253

Query: 146  I-----ERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEAE 200
            +     E    LE E      L E++Q+ + E R  R+E A ++  + P    PS+    
Sbjct: 1254 VPLQYNELKLALEKEKARCAELEEALQKTRIELRSAREEAAHRKATDHPH---PSTPATA 1310

Query: 201  RTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRR 234
            R   A+ A    P     H+  + SL  P S RR
Sbjct: 1311 RQQIAMSAIVRSPE----HQPSAMSLLAPPSSRR 1340



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 46/191 (24%), Positives = 84/191 (43%), Gaps = 31/191 (16%)

Query: 20   DLAMTYKQRAENTQEELREFQEGSREYEA---------ELETQLQQIETRNRDLLSENNR 70
            +L  T  +  E  Q       E  R+++A         +LE QL Q+   N +L ++N  
Sbjct: 910  ELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFY 969

Query: 71   LRMEL--------ETIKEKFEVQH-----SEGYRQISALEDDLAQTKAIKDQLQKYIREL 117
            L  +L        E ++ + EV H     +E   Q+++ +  +   K     L++ + +L
Sbjct: 970  LSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVMDL 1029

Query: 118  EQANDDL---ERAKRATIMSLEDFEQRLNQAIERNAFLESELD-EKENLLESVQRLKDEA 173
            E  ND+L   ER   A    L D + +    +     L+  LD EK++   + QR+ +  
Sbjct: 1030 EALNDELLEKERQWEAWRSVLGDEKSQFECRVRE---LQRMLDTEKQSRARADQRITESR 1086

Query: 174  RDLRQELAVQQ 184
            + +  ELAV++
Sbjct: 1087 QVV--ELAVKE 1095



 Score = 33.5 bits (75), Expect = 0.27
 Identities = 35/148 (23%), Positives = 69/148 (46%), Gaps = 20/148 (13%)

Query: 53  QLQQIETRNRDLLSENNRLRMELETIKEK-FEVQHSEGYRQISALEDDLAQTKAIKDQLQ 111
           ++ Q + +   LL +      +L+ IKE+ ++ Q  E    ++ LE+DL   +   D  +
Sbjct: 527 EVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYE 586

Query: 112 KYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKD 171
             +RE   A ++ +R  +AT     + + +L +A ++    + E+ E   L         
Sbjct: 587 SELRESRLAAEEFKR--KAT-----ECQHKLLKAKDQG---KPEVGEYAKL--------- 627

Query: 172 EARDLRQELAVQQKQEKPRTPMPSSVEA 199
           E  +  Q+L +Q+ QEK    + +S EA
Sbjct: 628 EKINAEQQLKIQELQEKLEKAVKASTEA 655



 Score = 32.7 bits (73), Expect = 0.47
 Identities = 36/184 (19%), Positives = 88/184 (47%), Gaps = 16/184 (8%)

Query: 12  EEEANYWKDLAMTYKQRAENTQEELREFQEGSR----EY------EAELETQLQQIETRN 61
           E E    +  A  +K++A   Q +L + ++  +    EY       AE + ++Q+++ + 
Sbjct: 586 ESELRESRLAAEEFKRKATECQHKLLKAKDQGKPEVGEYAKLEKINAEQQLKIQELQEKL 645

Query: 62  RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQAN 121
              +  +      L+ I++  E       R++  L++    ++ I+ +L +   ELE+ +
Sbjct: 646 EKAVKASTEATELLQNIRQAKE----RAERELEKLQNREDSSEGIRKKLVE-AEELEEKH 700

Query: 122 DDLERAKRATIMSLEDFEQRLNQAIE-RNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
            + + + +   + L+  EQ   + I+  +  ++ +L +KE L   +QR ++EA +  + L
Sbjct: 701 REAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEEAHEKGKIL 760

Query: 181 AVQQ 184
           + Q+
Sbjct: 761 SEQK 764


>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
          Length = 976

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 49/189 (25%), Positives = 89/189 (47%), Gaps = 25/189 (13%)

Query: 13  EEANYWKDLAMTYKQRAENTQE---ELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69
           E  ++   L++  K+  + T +   EL+  QE     + + E  L+QIE    +L     
Sbjct: 515 ELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIE----NLQETET 570

Query: 70  RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR 129
           +LR ELE ++E+ + +  E   ++   E++    +   +   KYI EL+Q N  L++   
Sbjct: 571 QLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGT 630

Query: 130 ATIMSLEDFEQRLNQAI-----------ERNAFLESELDEK----ENLLESVQRLK---D 171
           A    L  +E ++N+             E     + E+++K    ENLLE V++ K   D
Sbjct: 631 AESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIAD 690

Query: 172 EARDLRQEL 180
           EA  L++E+
Sbjct: 691 EAVKLQKEI 699



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 41/208 (19%), Positives = 88/208 (42%), Gaps = 20/208 (9%)

Query: 11  EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELE-------TQLQQIETRNRD 63
           E E+   WK       ++ E+  +E R+  E  R+   EL+        +L++    N+D
Sbjct: 112 EAEKIKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQELQFGNEKVSLKLEEGIQENKD 171

Query: 64  LLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDD 123
           L+ ENN  R     +KE       +  +     E+       + + ++K I   E+    
Sbjct: 172 LIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMITAFEELRVQ 231

Query: 124 LERAKRATIMSL-----------EDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDE 172
            E ++      L           +++++ +N   ++ + L  ++ EKEN ++ +  L +E
Sbjct: 232 AENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEE 291

Query: 173 ARDLRQELAVQQKQEKPRTPMPSSVEAE 200
           +RD   +L  ++K +     +  S+E +
Sbjct: 292 SRDKVNQL--EEKTKLQSENLKQSIEKQ 317



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 34/171 (19%), Positives = 84/171 (49%), Gaps = 12/171 (7%)

Query: 49  ELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKD 108
           +L+T+L+  + +N +L S  N+L +E + + +    + S+   ++   ++D+   K  ++
Sbjct: 501 DLKTELENEKLKNTELTSHCNKLSLENKELTQ----ETSDMTLELKNQQEDINNNKKQEE 556

Query: 109 QLQKYIRELE----QANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLE 164
           ++ K I  L+    Q  ++LE  +       ++ + +L+++ E    L  +++ K   +E
Sbjct: 557 RMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIE 616

Query: 165 SVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEAERTDTAVQATGSVPST 215
            +Q+   E + L+++   + KQ        + +E E  ++A Q  G +  T
Sbjct: 617 ELQQ---ENKALKKKGTAESKQLNVYEIKVNKLELE-LESAKQKFGEITDT 663



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 44/166 (26%), Positives = 77/166 (46%), Gaps = 23/166 (13%)

Query: 30  ENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEG 89
           EN  ++L    E SR+   +LE + +      +  + + + L  ELE I  K  +Q S  
Sbjct: 279 ENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDI--KVSLQRSVS 336

Query: 90  YRQISALEDDL-AQTKAIKDQLQKYIRELEQANDDLERAKRA----------TIMSLEDF 138
            ++  ALE+DL   TK I    ++   ++E++N    +A+ A          T+ SLE+ 
Sbjct: 337 TQK--ALEEDLQIATKTICQLTEEKETQMEESN----KARAAHSFVVTEFETTVCSLEEL 390

Query: 139 EQRLNQAIERN----AFLESELDEKENLLESVQRLKDEARDLRQEL 180
            +   Q +E+N      L  EL +K + LE + +L +      +EL
Sbjct: 391 LRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEEL 436



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 39/189 (20%), Positives = 84/189 (44%), Gaps = 21/189 (11%)

Query: 33  QEELREFQEGSREYEAELETQLQQI----------ETRNRDLLSENNRLRMELETIKEKF 82
           +E+  + Q   +EY+ E+  + +Q+          E + +DL       R ++  ++EK 
Sbjct: 244 KEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKT 303

Query: 83  EVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRL 142
           ++Q     + I        + + IK  LQ+ +   +   +DL+ A +      E+ E ++
Sbjct: 304 KLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQM 363

Query: 143 ---NQAIERNAFLESELDE-----KENLLESVQRL---KDEARDLRQELAVQQKQEKPRT 191
              N+A   ++F+ +E +      +E L    QRL   +D+ + L  EL  +  + +  T
Sbjct: 364 EESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMT 423

Query: 192 PMPSSVEAE 200
            + ++ E E
Sbjct: 424 KLTNNKEVE 432


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 41/179 (22%), Positives = 80/179 (44%), Gaps = 5/179 (2%)

Query: 26   KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
            K+R    Q+  R+ +E + ++EA   T    +  ++ D ++E       L+ +K+K E +
Sbjct: 1171 KKREAEFQKMRRDLEEATLQHEATAAT----LRKKHADSVAELGEQIDNLQRVKQKLEKE 1226

Query: 86   HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQA 145
             SE   +I  L  ++      K  L+K  R LE    +L+  +      + D   +  + 
Sbjct: 1227 KSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRL 1286

Query: 146  IERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQE-KPRTPMPSSVEAERTD 203
               +     +LDEKE L+  + R K       +EL  Q ++E K +  +  ++++ R D
Sbjct: 1287 QTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHD 1345



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 58/242 (23%), Positives = 108/242 (44%), Gaps = 47/242 (19%)

Query: 10   SEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69
            +EE++ N      +  +Q+ ++         EGS E E +L   L++ + +    L    
Sbjct: 1018 AEEDKVNTLTKAKIKLEQQVDDL--------EGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1069

Query: 70   RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL----- 124
               M++E  K++ + +  +   +IS L+  +   +A+  QLQK I+EL+   ++L     
Sbjct: 1070 ESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIE 1129

Query: 125  -ERAKRATI--------MSLEDFEQRLNQA-------IERNAFLESELDE-KENLLESVQ 167
             ERA RA            LE+  +RL +A       IE N   E+E  + + +L E+  
Sbjct: 1130 AERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATL 1189

Query: 168  RLKDEARDLRQELA---------------VQQKQEKPRTPMPSSVE--AERTDTAVQATG 210
            + +  A  LR++ A               V+QK EK ++ M   ++  A   +T  +A G
Sbjct: 1190 QHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKG 1249

Query: 211  SV 212
            ++
Sbjct: 1250 NL 1251



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 58/240 (24%), Positives = 116/240 (48%), Gaps = 43/240 (17%)

Query: 9    SSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYE---AELETQLQQIETRNRDLL 65
            + +EEE N      +T K+R    ++E  E ++   + E   A++E +    E + ++L 
Sbjct: 932  AEDEEEIN----AELTAKKR--KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 985

Query: 66   SENNRLRMELETI-KEKFEVQ--HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQAND 122
             E   L   +  + KEK  +Q  H +    + A ED +      K +L++ + +LE + +
Sbjct: 986  EEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLE 1045

Query: 123  -------DLERAKR----------ATIMSLEDFEQRLNQAIERNAF----LESELDEKEN 161
                   DLERAKR           +IM +E+ +Q+L++ +++  F    L+S++++++ 
Sbjct: 1046 QEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQA 1105

Query: 162  LLESVQ--------RLKDEARDLRQELAVQQKQEKPRTPMPSSVE--AERTDTAVQATGS 211
            L   +Q        R+++   ++  E A + K EK R+ +   +E  +ER + A  AT +
Sbjct: 1106 LGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA 1165



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 57/200 (28%), Positives = 91/200 (45%), Gaps = 46/200 (23%)

Query: 11   EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAEL-------ETQLQQIETRNRD 63
            ++++ N+ K LA  +KQ+ E T  EL   Q+ +R    EL       E  L Q+ET  R 
Sbjct: 1449 DKKQRNFDKILA-EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKR- 1506

Query: 64   LLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDD 123
               EN  L+ E+  + E    Q +EG ++I  LE              K  +++EQ   +
Sbjct: 1507 ---ENKNLQQEISDLTE----QIAEGGKRIHELE--------------KIKKQVEQEKCE 1545

Query: 124  LERAKRATIMSLEDFEQR-------LNQA---IERN-AFLESELDE-KEN---LLESVQR 168
            L+ A      SLE  E +       LNQ    ++R  A  + E+D+ K N   ++ES+Q 
Sbjct: 1546 LQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQS 1605

Query: 169  LKD-EARDLRQELAVQQKQE 187
              D E R     + +++K E
Sbjct: 1606 TLDAEIRSRNDAIRLKKKME 1625



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 30/118 (25%), Positives = 64/118 (54%), Gaps = 22/118 (18%)

Query: 74  ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIM 133
           E+ T+KE+F+            ++D+LA+++A + +L++ +  L +  +DL+   +A   
Sbjct: 854 EMATMKEEFQ-----------KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAE 902

Query: 134 SLEDFEQRLNQAIERNAFLESEL--------DEKE---NLLESVQRLKDEARDLRQEL 180
            L D E+R +Q I+    LE+++        DE+E    L    ++L+DE  +L++++
Sbjct: 903 GLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960



 Score = 36.2 bits (82), Expect = 0.042
 Identities = 53/189 (28%), Positives = 79/189 (41%), Gaps = 42/189 (22%)

Query: 9    SSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQL--------QQIETR 60
            S EEE+     DL     QR    Q E  EF     E EA L +QL        QQIE  
Sbjct: 1267 SKEEEQQRLINDLTA---QRGR-LQTESGEFSRQLDEKEA-LVSQLSRGKQAFTQQIEEL 1321

Query: 61   NRDLLSE---NNRL-------RMELETIKEKFEVQH---SEGYRQISALEDDLAQTKAIK 107
             R L  E    N L       R + + ++E++E +    +E  R +S    ++AQ +   
Sbjct: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRT-- 1379

Query: 108  DQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQ 167
                KY  +  Q  ++LE AK+     L+  E+ +     + A LE          ++ Q
Sbjct: 1380 ----KYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLE----------KTKQ 1425

Query: 168  RLKDEARDL 176
            RL++E  DL
Sbjct: 1426 RLQNEVEDL 1434



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 46/207 (22%), Positives = 86/207 (41%), Gaps = 31/207 (14%)

Query: 27   QRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLS--ENNRLRM--ELETIKEKF 82
            Q + +  + LRE  E  +E +AEL+  L +  T      +  E + ++   ELE  K+K 
Sbjct: 1340 QSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKL 1399

Query: 83   EVQHSEGYRQISALEDDLAQTKAIKDQLQKYIREL----EQAN---DDLERAKRATIMSL 135
              +       + A+    A  +  K +LQ  + +L    E+ N     L++ +R     L
Sbjct: 1400 AQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKIL 1459

Query: 136  EDFEQRLNQAIE-------------------RNAFLESELDEKENLLESVQRLKDEARDL 176
             +++Q+  +                      +NA+ ES LD+ E L    + L+ E  DL
Sbjct: 1460 AEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEES-LDQLETLKRENKNLQQEISDL 1518

Query: 177  RQELAVQQKQEKPRTPMPSSVEAERTD 203
             +++A   K+      +   VE E+ +
Sbjct: 1519 TEQIAEGGKRIHELEKIKKQVEQEKCE 1545


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 41/179 (22%), Positives = 80/179 (44%), Gaps = 5/179 (2%)

Query: 26   KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
            K+R    Q+  R+ +E + ++EA   T    +  ++ D ++E       L+ +K+K E +
Sbjct: 1171 KKREAEFQKMRRDLEEATLQHEATAAT----LRKKHADSVAELGEQIDNLQRVKQKLEKE 1226

Query: 86   HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQA 145
             SE   +I  L  ++      K  L+K  R LE    +L+  +      + D   +  + 
Sbjct: 1227 KSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRL 1286

Query: 146  IERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQE-KPRTPMPSSVEAERTD 203
               +     +LDEKE L+  + R K       +EL  Q ++E K +  +  ++++ R D
Sbjct: 1287 QTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHD 1345



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 58/242 (23%), Positives = 108/242 (44%), Gaps = 47/242 (19%)

Query: 10   SEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69
            +EE++ N      +  +Q+ ++         EGS E E +L   L++ + +    L    
Sbjct: 1018 AEEDKVNTLTKAKIKLEQQVDDL--------EGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1069

Query: 70   RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL----- 124
               M++E  K++ + +  +   +IS L+  +   +A+  QLQK I+EL+   ++L     
Sbjct: 1070 ESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIE 1129

Query: 125  -ERAKRATI--------MSLEDFEQRLNQA-------IERNAFLESELDE-KENLLESVQ 167
             ERA RA            LE+  +RL +A       IE N   E+E  + + +L E+  
Sbjct: 1130 AERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATL 1189

Query: 168  RLKDEARDLRQELA---------------VQQKQEKPRTPMPSSVE--AERTDTAVQATG 210
            + +  A  LR++ A               V+QK EK ++ M   ++  A   +T  +A G
Sbjct: 1190 QHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKG 1249

Query: 211  SV 212
            ++
Sbjct: 1250 NL 1251



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 58/240 (24%), Positives = 116/240 (48%), Gaps = 43/240 (17%)

Query: 9    SSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYE---AELETQLQQIETRNRDLL 65
            + +EEE N      +T K+R    ++E  E ++   + E   A++E +    E + ++L 
Sbjct: 932  AEDEEEIN----AELTAKKR--KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 985

Query: 66   SENNRLRMELETI-KEKFEVQ--HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQAND 122
             E   L   +  + KEK  +Q  H +    + A ED +      K +L++ + +LE + +
Sbjct: 986  EEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLE 1045

Query: 123  -------DLERAKR----------ATIMSLEDFEQRLNQAIERNAF----LESELDEKEN 161
                   DLERAKR           +IM +E+ +Q+L++ +++  F    L+S++++++ 
Sbjct: 1046 QEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQA 1105

Query: 162  LLESVQ--------RLKDEARDLRQELAVQQKQEKPRTPMPSSVE--AERTDTAVQATGS 211
            L   +Q        R+++   ++  E A + K EK R+ +   +E  +ER + A  AT +
Sbjct: 1106 LGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA 1165



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 57/200 (28%), Positives = 91/200 (45%), Gaps = 46/200 (23%)

Query: 11   EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAEL-------ETQLQQIETRNRD 63
            ++++ N+ K LA  +KQ+ E T  EL   Q+ +R    EL       E  L Q+ET  R 
Sbjct: 1449 DKKQRNFDKILA-EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKR- 1506

Query: 64   LLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDD 123
               EN  L+ E+  + E    Q +EG ++I  LE              K  +++EQ   +
Sbjct: 1507 ---ENKNLQQEISDLTE----QIAEGGKRIHELE--------------KIKKQVEQEKCE 1545

Query: 124  LERAKRATIMSLEDFEQR-------LNQA---IERN-AFLESELDE-KEN---LLESVQR 168
            L+ A      SLE  E +       LNQ    ++R  A  + E+D+ K N   ++ES+Q 
Sbjct: 1546 LQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQS 1605

Query: 169  LKD-EARDLRQELAVQQKQE 187
              D E R     + +++K E
Sbjct: 1606 TLDAEIRSRNDAIRLKKKME 1625



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 30/118 (25%), Positives = 64/118 (54%), Gaps = 22/118 (18%)

Query: 74  ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIM 133
           E+ T+KE+F+            ++D+LA+++A + +L++ +  L +  +DL+   +A   
Sbjct: 854 EMATMKEEFQ-----------KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAE 902

Query: 134 SLEDFEQRLNQAIERNAFLESEL--------DEKE---NLLESVQRLKDEARDLRQEL 180
            L D E+R +Q I+    LE+++        DE+E    L    ++L+DE  +L++++
Sbjct: 903 GLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 960



 Score = 36.2 bits (82), Expect = 0.042
 Identities = 53/189 (28%), Positives = 79/189 (41%), Gaps = 42/189 (22%)

Query: 9    SSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQL--------QQIETR 60
            S EEE+     DL     QR    Q E  EF     E EA L +QL        QQIE  
Sbjct: 1267 SKEEEQQRLINDLTA---QRGR-LQTESGEFSRQLDEKEA-LVSQLSRGKQAFTQQIEEL 1321

Query: 61   NRDLLSE---NNRL-------RMELETIKEKFEVQH---SEGYRQISALEDDLAQTKAIK 107
             R L  E    N L       R + + ++E++E +    +E  R +S    ++AQ +   
Sbjct: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRT-- 1379

Query: 108  DQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQ 167
                KY  +  Q  ++LE AK+     L+  E+ +     + A LE          ++ Q
Sbjct: 1380 ----KYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLE----------KTKQ 1425

Query: 168  RLKDEARDL 176
            RL++E  DL
Sbjct: 1426 RLQNEVEDL 1434



 Score = 35.0 bits (79), Expect = 0.094
 Identities = 46/207 (22%), Positives = 86/207 (41%), Gaps = 31/207 (14%)

Query: 27   QRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLS--ENNRLRM--ELETIKEKF 82
            Q + +  + LRE  E  +E +AEL+  L +  T      +  E + ++   ELE  K+K 
Sbjct: 1340 QSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKL 1399

Query: 83   EVQHSEGYRQISALEDDLAQTKAIKDQLQKYIREL----EQAN---DDLERAKRATIMSL 135
              +       + A+    A  +  K +LQ  + +L    E+ N     L++ +R     L
Sbjct: 1400 AQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKIL 1459

Query: 136  EDFEQRLNQAIE-------------------RNAFLESELDEKENLLESVQRLKDEARDL 176
             +++Q+  +                      +NA+ ES LD+ E L    + L+ E  DL
Sbjct: 1460 AEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEES-LDQLETLKRENKNLQQEISDL 1518

Query: 177  RQELAVQQKQEKPRTPMPSSVEAERTD 203
             +++A   K+      +   VE E+ +
Sbjct: 1519 TEQIAEGGKRIHELEKIKKQVEQEKCE 1545


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 48/186 (25%), Positives = 91/186 (48%), Gaps = 19/186 (10%)

Query: 26   KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
            K+R    Q+  R+ +E + ++EA        +  ++ D ++E       L+ +K+K E +
Sbjct: 1167 KKREAEFQKMRRDLEEATLQHEATAAA----LRKKHADSVAELGEQIDNLQRVKQKLEKE 1222

Query: 86   HSEGYRQISALEDDLAQTKAIKDQLQKYIRELE-QAND---DLERAKRATIMSLEDFEQR 141
             SE   ++  +  ++ Q    K  L+K  R LE QAN+    LE A+R    SL DF  +
Sbjct: 1223 KSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQR----SLNDFTTQ 1278

Query: 142  LNQAIERNAFLESELDEKENLLESVQRLK----DEARDLRQELAVQQKQEKPRTPMPSSV 197
              +    N  L  +L+EKE L+  + R K     +  DL+++L   +++ K +  +  ++
Sbjct: 1279 RAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQL---EEEGKAKNALAHAL 1335

Query: 198  EAERTD 203
            ++ R D
Sbjct: 1336 QSARHD 1341



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 48/182 (26%), Positives = 86/182 (47%), Gaps = 19/182 (10%)

Query: 22   AMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEK 81
            A+  KQR  N  + L E+++   E ++ELE+  ++  + + +L    N     LE + E 
Sbjct: 1443 ALDKKQR--NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL-ET 1499

Query: 82   FEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQR 141
            F+ ++     +IS L + L +      +L+K  ++LE    +L+ A      SLE  E +
Sbjct: 1500 FKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGK 1559

Query: 142  LNQA-IERN---AFLESELDEKENLLESVQR------------LKDEARDLRQELAVQQK 185
            + +A +E N   A +E +L EK+  +E  +R            L  E R   + L V++K
Sbjct: 1560 ILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKK 1619

Query: 186  QE 187
             E
Sbjct: 1620 ME 1621



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 42/180 (23%), Positives = 74/180 (41%), Gaps = 17/180 (9%)

Query: 26   KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
            +++     EE+ + +   +     L+T L   ETR+R+   E  R++ ++E    + E+Q
Sbjct: 1575 ERKLAEKDEEMEQAKRNHQRVVDSLQTSLDA-ETRSRN---EVLRVKKKMEGDLNEMEIQ 1630

Query: 86   HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL-------ERAKRATIMSLEDF 138
             S   R  +  +  +   +++    Q  + +  +ANDDL       ER        LE+ 
Sbjct: 1631 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEEL 1690

Query: 139  EQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVE 198
               + Q        E EL E     E VQ L  +   L  +   ++K E   T + S VE
Sbjct: 1691 RAVVEQTERSRKLAEQELIETS---ERVQLLHSQNTSLINQ---KKKMESDLTQLQSEVE 1744



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 28/118 (23%), Positives = 60/118 (50%), Gaps = 22/118 (18%)

Query: 74  ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIM 133
           E+ T+KE+F             +++ L +++A + +L++ +  L Q  +DL+   +A   
Sbjct: 850 EMATMKEEF-----------GRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 898

Query: 134 SLEDFEQRLNQAIERNAFLESELDEKENLLESVQ-----------RLKDEARDLRQEL 180
           +L D E+R +Q I+    LE+++ E    LE  +           +L+DE  +L++++
Sbjct: 899 NLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDI 956



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 48/196 (24%), Positives = 96/196 (48%), Gaps = 36/196 (18%)

Query: 11   EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEA---ELETQLQQIETRNRDLLSE 67
            EE++ N      +  +Q+ ++ +  L + ++   + E    +LE  L+  +    DL  E
Sbjct: 1015 EEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDL--E 1072

Query: 68   NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRE----LEQANDD 123
            N++L++E +  K++F++      +Q S +ED+    + +  QLQK ++E    +E+  ++
Sbjct: 1073 NDKLQLEEKLKKKEFDIN-----QQNSKIEDE----QVLALQLQKKLKENQARIEELEEE 1123

Query: 124  L--ERAKRATI--------MSLEDFEQRLNQA-------IERNAFLESELDE-KENLLES 165
            L  ER  RA +          LE+  +RL +A       IE N   E+E  + + +L E+
Sbjct: 1124 LEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEA 1183

Query: 166  VQRLKDEARDLRQELA 181
              + +  A  LR++ A
Sbjct: 1184 TLQHEATAAALRKKHA 1199



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 51/231 (22%), Positives = 100/231 (43%), Gaps = 35/231 (15%)

Query: 1    MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEEL-REFQE----------GSREYEAE 49
            +ED    +  + EEA    +   T + + +    EL R+ +E          G   Y  +
Sbjct: 1254 LEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQ 1313

Query: 50   LETQLQQIETRNRD---LLSENNRLRMELETIKEKFEVQ---HSEGYRQISALEDDLAQT 103
            +E   +Q+E   +    L       R + + ++E++E +    +E  R +S    ++AQ 
Sbjct: 1314 MEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQW 1373

Query: 104  KAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESE----LDEK 159
            +       KY  +  Q  ++LE AK+     L+D E+ +     + + LE       +E 
Sbjct: 1374 RT------KYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEI 1427

Query: 160  ENLLESVQR-------LKDEARDLRQELAV-QQKQEKPRTPMPSSVEAERT 202
            E+L+  V+R       L  + R+  + LA  +QK E+ ++ + SS +  R+
Sbjct: 1428 EDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS 1478



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 43/210 (20%), Positives = 93/210 (44%), Gaps = 38/210 (18%)

Query: 12   EEEANYWKDLAMTYKQRAENTQEELREFQ---EGSREYEAELETQLQQIETRNRDLLSEN 68
            E + ++   +A   +++ ++ Q  L++ Q   + +     +L+  +  +E RN  L +E 
Sbjct: 1628 EIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAEL 1687

Query: 69   NRLR--------------MELETIKEKFEVQHSEG---YRQISALEDDLAQTKAIKDQLQ 111
              LR               EL    E+ ++ HS+      Q   +E DL Q   ++ +++
Sbjct: 1688 EELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQ---LQSEVE 1744

Query: 112  KYIRELEQANDDLERAKRATIMSLEDFE---------QRLNQAIERNAF-LESELDEKEN 161
            + ++E   A +  ++A     M  E+ +         +R+ + +E+    L+  LDE E 
Sbjct: 1745 EAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1804

Query: 162  LL-----ESVQRLKDEARDLRQELAVQQKQ 186
            +      + +Q+L+   R+L  EL  +QK+
Sbjct: 1805 IALKGGKKQLQKLEARVRELEGELEAEQKR 1834



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 33/141 (23%), Positives = 61/141 (43%), Gaps = 17/141 (12%)

Query: 38   EFQEGSREYEAELETQLQQIETRNRD----------LLSENNRLRMELETIKEKFEVQHS 87
            EF +   E E +L  + +++E   R+           L    R R E+  +K+K E   +
Sbjct: 1566 EFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLN 1625

Query: 88   EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIE 147
            E   Q+S      A+ +     LQ  +++ +   DD  RA        +D ++ +     
Sbjct: 1626 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRAN-------DDLKENIAIVER 1678

Query: 148  RNAFLESELDEKENLLESVQR 168
            RN  L++EL+E   ++E  +R
Sbjct: 1679 RNNLLQAELEELRAVVEQTER 1699



 Score = 37.0 bits (84), Expect = 0.025
 Identities = 35/177 (19%), Positives = 80/177 (45%), Gaps = 15/177 (8%)

Query: 13   EEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAEL----ETQLQQIETRNRDLLSEN 68
            EE    +D +   ++  +N ++ +++ Q    E E       + QLQ++E R R+L  E 
Sbjct: 1769 EELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGE- 1827

Query: 69   NRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128
                +E E      + +++E  + +   E  + +     ++ +K +  L+   D L+   
Sbjct: 1828 ----LEAE------QKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKV 1877

Query: 129  RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQK 185
            +A     E+ E++ N  + +   ++ ELDE E   +  +   ++ R   +++  +QK
Sbjct: 1878 KAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKQK 1934



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 43/172 (25%), Positives = 78/172 (45%), Gaps = 14/172 (8%)

Query: 13   EEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLS--ENNR 70
            EE    K+      Q A +  + LRE  E   E +AEL+  L +  +      +  E + 
Sbjct: 1322 EEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1381

Query: 71   LRM--ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128
            ++   ELE  K+K   +  +    + A+    +  +  K +LQ    E+E    D+ER+ 
Sbjct: 1382 IQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQN---EIEDLMVDVERS- 1437

Query: 129  RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
             A   +L+  ++  ++ +   A  + + +E ++ LES Q+   EAR L  EL
Sbjct: 1438 NAAAAALDKKQRNFDKIL---AEWKQKYEESQSELESSQK---EARSLSTEL 1483



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 36/145 (24%), Positives = 62/145 (42%), Gaps = 18/145 (12%)

Query: 43  SREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQ 102
           S E E E+ T  ++   R ++ L ++   R ELE        + ++   Q+ A +D+L  
Sbjct: 844 SAETEKEMATMKEEFG-RIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLND 902

Query: 103 TKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENL 162
            +   DQL K   +LE                +++  +RL    E NA L +   +K  L
Sbjct: 903 AEERCDQLIKNKIQLE--------------AKVKEMNERLEDEEEMNAELTA---KKRKL 945

Query: 163 LESVQRLKDEARDLRQELAVQQKQE 187
            +    LK +  DL   LA  +K++
Sbjct: 946 EDECSELKKDIDDLELTLAKVEKEK 970



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 38/172 (22%), Positives = 75/172 (43%), Gaps = 15/172 (8%)

Query: 31   NTQEELREFQEGSREYEAELET---QLQQIETRNRDLLSENNRLRMELETIKEKFEVQHS 87
            N ++  R  ++ + EY  +LE     L    T+   L +EN  L  +LE  KE    Q +
Sbjct: 1246 NLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEE-KEALISQLT 1304

Query: 88   EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIE 147
             G          L+ T+ ++D L++ + E  +A + L  A ++     +   ++  +  E
Sbjct: 1305 RG---------KLSYTQQMED-LKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETE 1354

Query: 148  RNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEA 199
              A L+  L  K N   +  R K E   +++   +++ ++K    +  + EA
Sbjct: 1355 AKAELQRVL-SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEA 1405


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 56/189 (29%), Positives = 90/189 (47%), Gaps = 24/189 (12%)

Query: 11   EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAEL-------ETQLQQIETRNRD 63
            ++++ N+ K L+  +KQ+ E TQ EL   Q+ SR    EL       E  L Q+ET  R 
Sbjct: 1446 DKKQRNFDKVLS-EWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRR- 1503

Query: 64   LLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDD 123
               EN  L+ E+  + E    Q +EG +QI  LE    Q +  K ++Q     LE+A   
Sbjct: 1504 ---ENKNLQQEISDLTE----QIAEGGKQIHELEKIKKQVEQEKCEIQ---AALEEAEAS 1553

Query: 124  LERAKRATIMSLEDFEQRLNQAIERNAFLESELDE-KEN---LLESVQRLKD-EARDLRQ 178
            LE  +   +    +  Q  ++   + A  + E+D+ K N   ++E++Q   D E R    
Sbjct: 1554 LEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRND 1613

Query: 179  ELAVQQKQE 187
             L V++K E
Sbjct: 1614 ALRVKKKME 1622



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 42/186 (22%), Positives = 85/186 (45%), Gaps = 19/186 (10%)

Query: 26   KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
            K+R    Q+  R+ +E + ++EA     +  +  ++ D ++E       L+ +K+K E +
Sbjct: 1168 KKREAEFQKLRRDLEEATLQHEA----MVAALRKKHADSMAELGEQIDNLQRVKQKLEKE 1223

Query: 86   HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQA 145
             SE   +   L  +       K  L+K  R LE    +L+  +       E+ ++ +N  
Sbjct: 1224 KSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKE-------EEQQRLINDL 1276

Query: 146  IERNAFLESE-------LDEKENLLESVQRLKDEARDLRQELAVQQKQE-KPRTPMPSSV 197
              + A L++E       LDEK+ L+  + R K  +    +EL  Q ++E K +  +  ++
Sbjct: 1277 TAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHAL 1336

Query: 198  EAERTD 203
            ++ R D
Sbjct: 1337 QSSRHD 1342



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 51/203 (25%), Positives = 88/203 (43%), Gaps = 37/203 (18%)

Query: 28   RAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHS 87
            +A+   E+  +  EGS E E +L   L++ + +    L       M++E  K++ + +  
Sbjct: 1025 KAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLE 1084

Query: 88   EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL------ERAKRATI--------M 133
            +   +IS L   +   +A++ QLQK I+EL+   ++L      ERA RA           
Sbjct: 1085 KKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSR 1144

Query: 134  SLEDFEQRLNQA-------IERNAFLESELDEKENLLES--------VQRLKDEARDLRQ 178
             LE+  +RL +A       +E N   E+E  +    LE         V  L+ +  D   
Sbjct: 1145 ELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMA 1204

Query: 179  ELA--------VQQKQEKPRTPM 193
            EL         V+QK EK ++ +
Sbjct: 1205 ELGEQIDNLQRVKQKLEKEKSEL 1227



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 28/118 (23%), Positives = 60/118 (50%), Gaps = 22/118 (18%)

Query: 74  ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIM 133
           E+ T+KE+F+             +D+LA+++A + +L++ +  L +  +DL+   ++   
Sbjct: 851 EMATMKEEFQ-----------KTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEAD 899

Query: 134 SLEDFEQRLNQAIERNAFLESELDE-----------KENLLESVQRLKDEARDLRQEL 180
           SL D E+R  Q I+    LE+++ E              L    ++L+DE  +L++++
Sbjct: 900 SLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDI 957



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 35/146 (23%), Positives = 71/146 (48%), Gaps = 21/146 (14%)

Query: 35   ELREFQEGSREYEAELETQLQQIETRNRDLLSEN-NRLRMELETIKEKFEVQH---SEGY 90
            +L   ++ S +   EL+ QL++ ET+ ++ L+      R + + ++E++E +    +E  
Sbjct: 1303 QLSRSKQASTQQIEELKHQLEE-ETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQ 1361

Query: 91   RQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNA 150
            R +S    ++AQ +       KY  +  Q  ++LE AK+     L++ E+ +     + A
Sbjct: 1362 RALSKANSEVAQWRT------KYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCA 1415

Query: 151  FLESELDEKENLLESVQRLKDEARDL 176
             LE          ++ QRL++E  DL
Sbjct: 1416 SLE----------KTKQRLQNEVEDL 1431



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 41/196 (20%), Positives = 79/196 (40%), Gaps = 25/196 (12%)

Query: 33   QEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQ 92
            +E+  E QEG  E +  L     ++        ++  +   ELE  K+K   +  E    
Sbjct: 1347 REQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEH 1406

Query: 93   ISALEDDLAQTKAIKDQLQKYIREL----EQAN---DDLERAKRATIMSLEDFEQRL--- 142
            + A+    A  +  K +LQ  + +L    E++N     L++ +R     L +++Q+    
Sbjct: 1407 VEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEET 1466

Query: 143  ----------NQAIERNAF-----LESELDEKENLLESVQRLKDEARDLRQELAVQQKQE 187
                      ++++    F      E  LD+ E L    + L+ E  DL +++A   KQ 
Sbjct: 1467 QAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQI 1526

Query: 188  KPRTPMPSSVEAERTD 203
                 +   VE E+ +
Sbjct: 1527 HELEKIKKQVEQEKCE 1542


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 41/182 (22%), Positives = 84/182 (46%), Gaps = 11/182 (6%)

Query: 26   KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
            K+R    Q+  R+ +E + ++EA        +  ++ D ++E       L+ +K+K E +
Sbjct: 1165 KKREAEFQKMRRDLEEATLQHEATAAA----LRKKHADSVAELGEQIDNLQRVKQKLEKE 1220

Query: 86   HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQA 145
             SE   ++  +  ++ Q    K  L+K  R LE   ++       T  S+ D   +  + 
Sbjct: 1221 KSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKL 1280

Query: 146  IERNAFLESELDEKENLLESVQRLK----DEARDLRQELAVQQKQEKPRTPMPSSVEAER 201
               N  L  +LDEKE L+  + R K     +  DL+++L   +++ K +  +  ++++ R
Sbjct: 1281 QTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL---EEEVKAKNALAHALQSAR 1337

Query: 202  TD 203
             D
Sbjct: 1338 HD 1339



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 48/182 (26%), Positives = 86/182 (47%), Gaps = 19/182 (10%)

Query: 22   AMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEK 81
            A+  KQR  N  + L E+++   E ++ELE+  ++  + + +L    N     LE + E 
Sbjct: 1441 ALDKKQR--NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHL-ET 1497

Query: 82   FEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQR 141
            F+ ++     +IS L + L  +     +L+K  ++LE    +L+ A      SLE  E +
Sbjct: 1498 FKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGK 1557

Query: 142  LNQA-IERN---AFLESELDEKENLLESVQR------------LKDEARDLRQELAVQQK 185
            + +A +E N   A +E +L EK+  +E  +R            L  E R   + L V++K
Sbjct: 1558 ILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKK 1617

Query: 186  QE 187
             E
Sbjct: 1618 ME 1619



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 57/226 (25%), Positives = 103/226 (45%), Gaps = 42/226 (18%)

Query: 11   EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAEL-------ETQLQQIET---R 60
            ++++ N+ K LA  +KQ+ E +Q EL   Q+ +R    EL       E  L+ +ET    
Sbjct: 1443 DKKQRNFDKILA-EWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRE 1501

Query: 61   NRDLLSENNRL------------------------RMELETIKEKFE--VQHSEGYRQIS 94
            N++L  E + L                        +MEL++  E+ E  ++H EG  +I 
Sbjct: 1502 NKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEG--KIL 1559

Query: 95   ALEDDLAQTKA-IKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLE 153
              + +  Q KA I+ +L +   E+EQA  +  R   +   SL+   +  N+A+     +E
Sbjct: 1560 RAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKME 1619

Query: 154  SELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEA 199
             +L+E E  L    R+  EA+  +Q  ++Q   +  +  +  +V A
Sbjct: 1620 GDLNEMEIQLSHANRMAAEAQ--KQVKSLQSLLKDTQIQLDDAVRA 1663



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 45/194 (23%), Positives = 89/194 (45%), Gaps = 30/194 (15%)

Query: 10   SEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69
            +EE++ N      +  +Q+ ++         EGS E E ++   L++ + +    L    
Sbjct: 1012 AEEDKVNTLTKAKVKLEQQVDDL--------EGSLEQEKKVRMDLERAKRKLEGDLKLTQ 1063

Query: 70   RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL----- 124
               M+LE  K++ + +  +   +++AL   +   +A+  QLQK ++EL+   ++L     
Sbjct: 1064 ESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELE 1123

Query: 125  -ERAKRATI--------MSLEDFEQRLNQA-------IERNAFLESELDE-KENLLESVQ 167
             ER  RA +          LE+  +RL +A       IE N   E+E  + + +L E+  
Sbjct: 1124 AERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATL 1183

Query: 168  RLKDEARDLRQELA 181
            + +  A  LR++ A
Sbjct: 1184 QHEATAAALRKKHA 1197



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 38/169 (22%), Positives = 80/169 (47%), Gaps = 24/169 (14%)

Query: 23  MTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKF 82
           M YK+  E  ++ L   Q   R +         ++  + + LL    R + E+ ++KE+F
Sbjct: 799 MEYKKLLER-RDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREK-EMASMKEEF 856

Query: 83  EVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRL 142
                      + L++ L +++A + +L++ +  L Q  +DL+   +A   +L D E+R 
Sbjct: 857 -----------TRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERC 905

Query: 143 NQAIERNAFLESELDEKENLLESVQ-----------RLKDEARDLRQEL 180
           +Q I+    LE+++ E    LE  +           +L+DE  +L++++
Sbjct: 906 DQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI 954



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 39/161 (24%), Positives = 69/161 (42%), Gaps = 11/161 (6%)

Query: 11   EEEEANYWKDLAMTYKQRAENTQ---EELREFQEGSREYEAELETQLQQIETRNRDLLSE 67
            EE EA+   +     + + E  Q   E  R+  E   E E      L+ +++    L +E
Sbjct: 1545 EEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAE 1604

Query: 68   NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127
              R R E   +K+K E   +E   Q+S      A+ +     LQ  +++ +   DD  RA
Sbjct: 1605 T-RSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1663

Query: 128  KRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQR 168
                    +D ++ +     RN  L++EL+E   ++E  +R
Sbjct: 1664 N-------DDLKENIAIVERRNNLLQAELEELRAVVEQTER 1697



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 37/158 (23%), Positives = 76/158 (48%), Gaps = 16/158 (10%)

Query: 34   EELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQI 93
            EELR   E +       E +L +   R + L S+N  L  +    K+K +   S+   ++
Sbjct: 1686 EELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQ----KKKMDADLSQLQTEV 1741

Query: 94   SALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLE 153
               E+ + + +  +++ +K I +     ++L++ ++ T   LE  ++ + Q I+    L+
Sbjct: 1742 ---EEAVQECRNAEEKAKKAITDAAMMAEELKK-EQDTSAHLERMKKNMEQTIKD---LQ 1794

Query: 154  SELDEKENLL-----ESVQRLKDEARDLRQELAVQQKQ 186
              LDE E +      + +Q+L+   R+L  EL  +QK+
Sbjct: 1795 HRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKR 1832



 Score = 35.4 bits (80), Expect = 0.072
 Identities = 46/173 (26%), Positives = 79/173 (45%), Gaps = 15/173 (8%)

Query: 12   EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLS--ENN 69
            EEE      LA    Q A +  + LRE  E   E +AEL+  L +  +      +  E +
Sbjct: 1320 EEEVKAKNALAHAL-QSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETD 1378

Query: 70   RLRM--ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127
             ++   ELE  K+K   +  E    + A+    +  +  K +LQ    E+E    D+ER+
Sbjct: 1379 AIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQN---EIEDLMVDVERS 1435

Query: 128  KRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
              A   +L+  ++  ++ +   A  + + +E ++ LES Q+   EAR L  EL
Sbjct: 1436 -NAAAAALDKKQRNFDKIL---AEWKQKYEESQSELESSQK---EARSLSTEL 1481



 Score = 33.1 bits (74), Expect = 0.36
 Identities = 39/191 (20%), Positives = 82/191 (42%), Gaps = 35/191 (18%)

Query: 26   KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
            +++     EE+ + +         L+T L   ETR+R+   E  R++ ++E    + E+Q
Sbjct: 1573 ERKLAEKDEEMEQAKRNHLRVVDSLQTSLDA-ETRSRN---EALRVKKKMEGDLNEMEIQ 1628

Query: 86   HS-------EGYRQISALE-----------------DDLAQTKAIKDQ----LQKYIREL 117
             S       E  +Q+ +L+                 DDL +  AI ++    LQ  + EL
Sbjct: 1629 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEEL 1688

Query: 118  EQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLR 177
                +  ER+++     L +  +R+     +N  L   +++K+ +   + +L+ E  +  
Sbjct: 1689 RAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL---INQKKKMDADLSQLQTEVEEAV 1745

Query: 178  QELAVQQKQEK 188
            QE    +++ K
Sbjct: 1746 QECRNAEEKAK 1756


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 39/190 (20%), Positives = 92/190 (48%), Gaps = 13/190 (6%)

Query: 12  EEEANYWKDLAMTYKQRAE---------NTQEELREFQEGSREYEAELETQLQQIETRNR 62
           E+E   W+     ++Q  +           +E++RE +E  RE E ++  Q ++I  ++ 
Sbjct: 322 EQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDE 381

Query: 63  DLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQL---QKYIRELEQ 119
            +  +   +  + E I+E+ E +  + +RQ   + +   + +  ++++   ++ IRELE+
Sbjct: 382 KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEE 441

Query: 120 ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQR-LKDEARDLRQ 178
              D E   R     +++ E+++ +  E+    E ++ E+E      ++ LK E +   Q
Sbjct: 442 MMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501

Query: 179 ELAVQQKQEK 188
           E  + +++EK
Sbjct: 502 EEKMWRQEEK 511



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 38/183 (20%), Positives = 90/183 (49%), Gaps = 13/183 (7%)

Query: 11  EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQI----ETRNRDLLS 66
           +EE+    ++     +++    +E++RE  E  +E E E+  Q ++I    E R   +  
Sbjct: 351 QEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWR 410

Query: 67  ENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLER 126
           +  ++R + E I+E    Q  E +RQ    E+ + + + +    ++ +RE+E+   + E 
Sbjct: 411 QEKKMREQDEKIRE----QEEEMWRQ----EEKIRELEEMMQDQEEKLREVEEKMQEEEE 462

Query: 127 AKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRL-KDEARDLRQELAVQQK 185
             +     ++  E+++ +  E+    E  L ++E + E  +++ + E +   QE  +Q++
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQ 522

Query: 186 QEK 188
           +EK
Sbjct: 523 EEK 525



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 40/218 (18%), Positives = 97/218 (44%), Gaps = 23/218 (10%)

Query: 1   MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
           M +  +    +EEE    ++     ++  ++ +E+LRE +E  +E E +++ Q ++I+ +
Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474

Query: 61  NRDLLSENNRLRMELETIK--EKFEVQHSEGYRQISAL---EDDLAQTKAIKDQLQKYIR 115
              +  +  +   + + +K  EK   Q  + +RQ   +   E+ + + +    + ++ +R
Sbjct: 475 EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMR 534

Query: 116 ELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLES-----------------ELDE 158
           E E      E   +   + L++ E+RL +  ++   L                   +++ 
Sbjct: 535 EQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVEL 594

Query: 159 KENLLESVQRLKDEAR-DLRQELAVQQKQEKPRTPMPS 195
           K    +S+Q+ +D  R  L+Q +A  Q+    +  +PS
Sbjct: 595 KSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEALPS 632



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 34/201 (16%), Positives = 93/201 (46%), Gaps = 13/201 (6%)

Query: 10  SEEEEANYWKDLAMTYKQRAENTQEEL--REFQEGSREYEAELETQLQQIETRNRDLLSE 67
           ++++E   W+      +Q  +  ++EL  RE +E     E ++  Q ++I  +   +  +
Sbjct: 292 NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQ 351

Query: 68  NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127
             ++R + E I+E    Q  + +RQ   + +   Q + I++Q ++  R+ E+  +  E+ 
Sbjct: 352 EEKIREQEEKIRE----QEEKMWRQEEKIRE---QDEKIQEQEEEMWRQEEKIREQEEKR 404

Query: 128 KRATIMS---LEDFEQRLNQAIERNAFLESELDEKENLL-ESVQRLKDEARDLRQELAVQ 183
           +         + + ++++ +  E     E ++ E E ++ +  ++L++    +++E    
Sbjct: 405 QEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKM 464

Query: 184 QKQEKPRTPMPSSVEAERTDT 204
           Q+QE+        ++ +   T
Sbjct: 465 QEQEEKIQRQEEKIQEQEEKT 485



 Score = 32.0 bits (71), Expect = 0.80
 Identities = 51/195 (26%), Positives = 91/195 (46%), Gaps = 31/195 (15%)

Query: 1   MEDSGKTFSSEEEEANYWKDLA-MTYKQRAENTQ-EELREFQEGSREYEAELETQLQQIE 58
           M +   TF         W  L  +T ++R EN+  EE   F    R     + T ++++ 
Sbjct: 142 MNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVR-----MGTYIEKL- 195

Query: 59  TRNRDLLS-ENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIREL 117
           T+ RD  S E  R  +  E +KEK            + L++ L   ++ K ++Q  +++L
Sbjct: 196 TKERDAPSLELYRNTITDEELKEKN-----------AELQEKLRLVESEKSEIQLNVKDL 244

Query: 118 EQANDDLERAKRATIMSLEDFE-QRLNQAIER-NAFLESELDEKE--NLLESVQRLKDEA 173
           ++    LERA+          E  RL + ++  +A L+++++E E  NLL   Q    E 
Sbjct: 245 KRK---LERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQ----EE 297

Query: 174 RDLRQELAVQQKQEK 188
           +  RQE  +Q+++EK
Sbjct: 298 KMWRQEEKIQEQEEK 312


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 39/190 (20%), Positives = 92/190 (48%), Gaps = 13/190 (6%)

Query: 12  EEEANYWKDLAMTYKQRAE---------NTQEELREFQEGSREYEAELETQLQQIETRNR 62
           E+E   W+     ++Q  +           +E++RE +E  RE E ++  Q ++I  ++ 
Sbjct: 322 EQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDE 381

Query: 63  DLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQL---QKYIRELEQ 119
            +  +   +  + E I+E+ E +  + +RQ   + +   + +  ++++   ++ IRELE+
Sbjct: 382 KIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEE 441

Query: 120 ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQR-LKDEARDLRQ 178
              D E   R     +++ E+++ +  E+    E ++ E+E      ++ LK E +   Q
Sbjct: 442 MMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501

Query: 179 ELAVQQKQEK 188
           E  + +++EK
Sbjct: 502 EEKMWRQEEK 511



 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 38/183 (20%), Positives = 90/183 (49%), Gaps = 13/183 (7%)

Query: 11  EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQI----ETRNRDLLS 66
           +EE+    ++     +++    +E++RE  E  +E E E+  Q ++I    E R   +  
Sbjct: 351 QEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWR 410

Query: 67  ENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLER 126
           +  ++R + E I+E    Q  E +RQ    E+ + + + +    ++ +RE+E+   + E 
Sbjct: 411 QEKKMREQDEKIRE----QEEEMWRQ----EEKIRELEEMMQDQEEKLREVEEKMQEEEE 462

Query: 127 AKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRL-KDEARDLRQELAVQQK 185
             +     ++  E+++ +  E+    E  L ++E + E  +++ + E +   QE  +Q++
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQ 522

Query: 186 QEK 188
           +EK
Sbjct: 523 EEK 525



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 40/218 (18%), Positives = 97/218 (44%), Gaps = 23/218 (10%)

Query: 1   MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
           M +  +    +EEE    ++     ++  ++ +E+LRE +E  +E E +++ Q ++I+ +
Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474

Query: 61  NRDLLSENNRLRMELETIK--EKFEVQHSEGYRQISAL---EDDLAQTKAIKDQLQKYIR 115
              +  +  +   + + +K  EK   Q  + +RQ   +   E+ + + +    + ++ +R
Sbjct: 475 EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMR 534

Query: 116 ELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLES-----------------ELDE 158
           E E      E   +   + L++ E+RL +  ++   L                   +++ 
Sbjct: 535 EQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVEL 594

Query: 159 KENLLESVQRLKDEAR-DLRQELAVQQKQEKPRTPMPS 195
           K    +S+Q+ +D  R  L+Q +A  Q+    +  +PS
Sbjct: 595 KSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEALPS 632



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 34/201 (16%), Positives = 93/201 (46%), Gaps = 13/201 (6%)

Query: 10  SEEEEANYWKDLAMTYKQRAENTQEEL--REFQEGSREYEAELETQLQQIETRNRDLLSE 67
           ++++E   W+      +Q  +  ++EL  RE +E     E ++  Q ++I  +   +  +
Sbjct: 292 NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQ 351

Query: 68  NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127
             ++R + E I+E    Q  + +RQ   + +   Q + I++Q ++  R+ E+  +  E+ 
Sbjct: 352 EEKIREQEEKIRE----QEEKMWRQEEKIRE---QDEKIQEQEEEMWRQEEKIREQEEKR 404

Query: 128 KRATIMS---LEDFEQRLNQAIERNAFLESELDEKENLL-ESVQRLKDEARDLRQELAVQ 183
           +         + + ++++ +  E     E ++ E E ++ +  ++L++    +++E    
Sbjct: 405 QEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKM 464

Query: 184 QKQEKPRTPMPSSVEAERTDT 204
           Q+QE+        ++ +   T
Sbjct: 465 QEQEEKIQRQEEKIQEQEEKT 485



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 52/195 (26%), Positives = 92/195 (47%), Gaps = 31/195 (15%)

Query: 1   MEDSGKTFSSEEEEANYWKDLA-MTYKQRAENTQ-EELREFQEGSREYEAELETQLQQIE 58
           M +   TF         W  L  +T ++R EN+  EE   F    R     + T ++++ 
Sbjct: 142 MNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVR-----MGTYIEKL- 195

Query: 59  TRNRDLLS-ENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIREL 117
           T+ RD LS E  R  +  E +KEK            + L++ L   ++ K ++Q  +++L
Sbjct: 196 TKERDALSLELYRNTITDEELKEKN-----------AELQEKLRLVESEKSEIQLNVKDL 244

Query: 118 EQANDDLERAKRATIMSLEDFE-QRLNQAIER-NAFLESELDEKE--NLLESVQRLKDEA 173
           ++    LERA+          E  RL + ++  +A L+++++E E  NLL   Q    E 
Sbjct: 245 KRK---LERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQ----EE 297

Query: 174 RDLRQELAVQQKQEK 188
           +  RQE  +Q+++EK
Sbjct: 298 KMWRQEEKIQEQEEK 312


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 43/184 (23%), Positives = 88/184 (47%), Gaps = 8/184 (4%)

Query: 11  EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDL------ 64
           +EEE    +      +++    +E LRE +   RE E ++  Q +++  + ++L      
Sbjct: 239 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKE 298

Query: 65  LSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL 124
           L E  +LR + E ++E+ E    +  +     E    Q + + +Q +K +RE EQ   D 
Sbjct: 299 LREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ-EKQMREQEQKMRDQ 357

Query: 125 ERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQ 184
           E         L + E+R+ +  E+    E ++ E+E + E  +++++E   +R++    Q
Sbjct: 358 EERMWEQDERLREKEERMREQ-EKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQ 416

Query: 185 KQEK 188
           KQE+
Sbjct: 417 KQEE 420



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 38/181 (20%), Positives = 83/181 (45%), Gaps = 2/181 (1%)

Query: 12  EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQI-ETRNRDLLSENNR 70
           E+E  + ++  M  ++R    ++++RE +E  RE E +++ Q + + E   ++   +   
Sbjct: 377 EQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 436

Query: 71  LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQL-QKYIRELEQANDDLERAKR 129
            + E    +EK + Q  + + Q   + D        K    Q+ +RE E    + E   R
Sbjct: 437 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 496

Query: 130 ATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKP 189
                + D E+R+ +  ER    E  + E++ + +  +++++E +   QE     ++EK 
Sbjct: 497 DQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKM 556

Query: 190 R 190
           R
Sbjct: 557 R 557



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 41/192 (21%), Positives = 95/192 (49%), Gaps = 15/192 (7%)

Query: 26  KQRAENTQEELREFQEGSREYEA--ELETQLQQ---IETRNRDLLSENNRLRMELETIKE 80
           ++R     E LRE +E  RE E   E E ++Q+   I  R + +  E   +R + E +++
Sbjct: 358 EERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQK 417

Query: 81  K----FEVQHSEGYRQ-ISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIM-- 133
           +    +E +  E  +Q +   ++ L + + +++Q +K   + E+  D  E   +   M  
Sbjct: 418 QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR 477

Query: 134 --SLEDFEQRLNQAIERNAFLESEL-DEKENLLESVQRLKDEARDLRQELAVQQKQEKPR 190
              + + E ++ +  E+    E ++ D++E + E  +RL+++   +R++  + Q++EK R
Sbjct: 478 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMR 537

Query: 191 TPMPSSVEAERT 202
               +  + ++T
Sbjct: 538 EEKKTQEQEKKT 549



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 34/182 (18%), Positives = 86/182 (47%), Gaps = 8/182 (4%)

Query: 11  EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70
           +E+E   W+       Q     QE+    QE  RE E ++  Q +++  + + +  +  R
Sbjct: 449 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 508

Query: 71  LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRA 130
           +  + E ++EK E    +  +++   E+ + + K  ++Q +K   + E+  ++    +R 
Sbjct: 509 MWEQDERLREKEERMREQ--KKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRERE 566

Query: 131 TIMSLEDFEQRLNQAIERNAFLESELDEKENLL----ESVQRLKDEARDLRQELAVQQKQ 186
             M  E  E+ + +  E+    E ++ E+E  +    E +Q  +++  +  +++  Q+++
Sbjct: 567 KKMREE--EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEE 624

Query: 187 EK 188
           +K
Sbjct: 625 DK 626



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 35/215 (16%), Positives = 99/215 (46%), Gaps = 20/215 (9%)

Query: 1   MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
           M +  KT   E+E+  + ++  M  ++R    ++++RE +E  RE E +++ Q +++  +
Sbjct: 536 MREEKKT--QEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQ 593

Query: 61  NRDLLSENNRLRMELETI------------KEKFEVQHSEGYRQISALEDD----LAQTK 104
              +  +  +++ + E +            ++K + Q    + Q   +++       Q +
Sbjct: 594 EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEE 653

Query: 105 AIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESEL-DEKENLL 163
            +++Q +K +RE E+     E   R     ++  E+++ +  E+    E ++  ++E + 
Sbjct: 654 KMREQEEK-MREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMW 712

Query: 164 ESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVE 198
              +++  +     +E  ++ ++EK +  +P   E
Sbjct: 713 GQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEE 747



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 40/180 (22%), Positives = 84/180 (46%), Gaps = 16/180 (8%)

Query: 13  EEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLR 72
           EE    +D       R   T EEL++         AEL+ +L+  E       SE + ++
Sbjct: 162 EELTKERDALSLELYRNTITNEELKK-------KNAELQEKLRLAE-------SEKSEIQ 207

Query: 73  MELETIKEKFE-VQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRAT 131
           + ++ +K K E  +      Q + L++++ + +    + +K IR+ E+     E   R  
Sbjct: 208 LNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQ 267

Query: 132 IMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLR-QELAVQQKQEKPR 190
              + + E+++ +  +R    E EL E+E  L   ++L+++   ++ QE  + +++EK R
Sbjct: 268 EGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMR 327



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 39/191 (20%), Positives = 75/191 (39%), Gaps = 28/191 (14%)

Query: 24  TYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRM------ELET 77
           T K++  N         EG    E E +   Q  E   R++ ++++ +R+      ELET
Sbjct: 47  TKKKKINNGTNPETTTSEGCHSPEDEKKASHQHQEALRREIEAQDHTIRILTCQKTELET 106

Query: 78  I-------KEKFE-------------VQHSEGYRQISALEDDLAQTKAIKDQLQKYIREL 117
                     KFE             + HS  +     L+  L+       +  +YI EL
Sbjct: 107 ALYYSQDAARKFEDGNLGESKDLAGRLHHS--WHFAGELQRALSAVSTWHKKADRYIEEL 164

Query: 118 EQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLR 177
            +  D L        ++ E+ +++  +  E+    ESE  E +  ++ ++R  + A+ L 
Sbjct: 165 TKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLL 224

Query: 178 QELAVQQKQEK 188
            ++     QE+
Sbjct: 225 PQVQTNTLQEE 235


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 41/170 (24%), Positives = 79/170 (46%), Gaps = 11/170 (6%)

Query: 26  KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
           +QR EN + +    Q   ++ E +   +L++++ +  + L +  + R  +E +KE+ + Q
Sbjct: 539 RQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQ 598

Query: 86  HSEGYRQIS-----ALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQ 140
             + + QI      A E+ LA+ KA K    K + E+E      E A+R   +  E+ E+
Sbjct: 599 IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER 658

Query: 141 RLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPR 190
           R          L+ + +E++  L      K  A    QE   Q+++E+ R
Sbjct: 659 R------HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER 702



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 58/233 (24%), Positives = 92/233 (39%), Gaps = 26/233 (11%)

Query: 24  TYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFE 83
           T K + E   EE  + +  +++ E     + Q+ E R    L +    R   E +++K E
Sbjct: 610 TEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE 669

Query: 84  VQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLN 143
            +  E  R+        A+ K + +Q ++  RE E+   +    +R      E   Q   
Sbjct: 670 -EEQERLRKA-------AEAKRLAEQREQERREQERREQERREQERREQERREQERQLAE 721

Query: 144 QAIERNAF---LESELDEKENLL----ESVQRLKDEAR--DLRQELAVQQKQEKPRTPMP 194
           Q   R       E EL E+E  L    E +QR  +E +  + +Q LA +Q QE+      
Sbjct: 722 QERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 781

Query: 195 SSVEAERT-----DTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGL--DDST 240
            +  A +      D    A  S   TP  HR P      P ++   L  DDST
Sbjct: 782 EAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKI--NPDNYGMDLNSDDST 832



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 36/157 (22%), Positives = 71/157 (45%), Gaps = 5/157 (3%)

Query: 11  EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70
           EEEE  + + L    +++ E  QE LR+  E  R  E + E + ++ E R ++   +  R
Sbjct: 654 EEEERRHQELL----QKKKEEEQERLRKAAEAKRLAE-QREQERREQERREQERREQERR 708

Query: 71  LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRA 130
            +   E  ++  E +      ++ A  +   + KA++ Q ++  RELE+     E+ + A
Sbjct: 709 EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLA 768

Query: 131 TIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQ 167
                E+ E++  +A   +  L   +D +     S Q
Sbjct: 769 ERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQ 805


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 41/170 (24%), Positives = 79/170 (46%), Gaps = 11/170 (6%)

Query: 26  KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
           +QR EN + +    Q   ++ E +   +L++++ +  + L +  + R  +E +KE+ + Q
Sbjct: 535 RQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQ 594

Query: 86  HSEGYRQIS-----ALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQ 140
             + + QI      A E+ LA+ KA K    K + E+E      E A+R   +  E+ E+
Sbjct: 595 IEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEER 654

Query: 141 RLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPR 190
           R          L+ + +E++  L      K  A    QE   Q+++E+ R
Sbjct: 655 R------HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER 698



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 58/233 (24%), Positives = 92/233 (39%), Gaps = 26/233 (11%)

Query: 24  TYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFE 83
           T K + E   EE  + +  +++ E     + Q+ E R    L +    R   E +++K E
Sbjct: 606 TEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKE 665

Query: 84  VQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLN 143
            +  E  R+        A+ K + +Q ++  RE E+   +    +R      E   Q   
Sbjct: 666 -EEQERLRKA-------AEAKRLAEQREQERREQERREQERREQERREQERREQERQLAE 717

Query: 144 QAIERNAF---LESELDEKENLL----ESVQRLKDEAR--DLRQELAVQQKQEKPRTPMP 194
           Q   R       E EL E+E  L    E +QR  +E +  + +Q LA +Q QE+      
Sbjct: 718 QERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 777

Query: 195 SSVEAERT-----DTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGL--DDST 240
            +  A +      D    A  S   TP  HR P      P ++   L  DDST
Sbjct: 778 EAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKI--NPDNYGMDLNSDDST 828



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 36/157 (22%), Positives = 71/157 (45%), Gaps = 5/157 (3%)

Query: 11  EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70
           EEEE  + + L    +++ E  QE LR+  E  R  E + E + ++ E R ++   +  R
Sbjct: 650 EEEERRHQELL----QKKKEEEQERLRKAAEAKRLAE-QREQERREQERREQERREQERR 704

Query: 71  LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRA 130
            +   E  ++  E +      ++ A  +   + KA++ Q ++  RELE+     E+ + A
Sbjct: 705 EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLA 764

Query: 131 TIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQ 167
                E+ E++  +A   +  L   +D +     S Q
Sbjct: 765 ERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQ 801


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 46/196 (23%), Positives = 86/196 (43%), Gaps = 6/196 (3%)

Query: 12   EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL 71
            +EE    +      +Q+     EEL E  E  +  +A L+   Q +E  N DL  E   L
Sbjct: 1184 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1243

Query: 72   ---RMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128
               + E+E  K+K E Q  E   + S  E   A+   + D++ K   E+E     L  A+
Sbjct: 1244 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVTGMLNEAE 1300

Query: 129  RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
               I   +D     +Q  +    L+ E  +K N+   +++L++E   L+ +L  + + ++
Sbjct: 1301 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1360

Query: 189  PRTPMPSSVEAERTDT 204
                  S++  + +D+
Sbjct: 1361 NLERHISTLNIQLSDS 1376



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 44/199 (22%), Positives = 92/199 (46%), Gaps = 22/199 (11%)

Query: 11   EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70
            +EEE    +D     K+R +  + EL+E ++   +   E     +Q++    +L +E   
Sbjct: 850  QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEE 908

Query: 71   LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR- 129
            +R+ L   K++ E    E   ++   ED   Q +A + ++ + + +LE+  ++ E A++ 
Sbjct: 909  MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 968

Query: 130  ---------ATIMSLED----FEQRLNQAIERNAFLE-------SELDEKENLLESVQRL 169
                     A I  LED     + + N+  +    LE       + L E+E   +++ +L
Sbjct: 969  LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKL 1028

Query: 170  KDEARDLRQELAVQQKQEK 188
            K++   +  EL V+ K+E+
Sbjct: 1029 KNKHESMISELEVRLKKEE 1047



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 48/179 (26%), Positives = 83/179 (46%), Gaps = 26/179 (14%)

Query: 11   EEEEANY--WKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSEN 68
            EEE+ N     D      Q+AE    EL       R    + E+  QQ+E +N++L S+ 
Sbjct: 1746 EEEQGNMEAMSDRVRKATQQAEQLSNELAT----ERSTAQKNESARQQLERQNKELRSKL 1801

Query: 69   NRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL---E 125
            + +      +K KF+         I+ALE  +AQ   +++Q+++  RE + A   L   +
Sbjct: 1802 HEME---GAVKSKFK-------STIAALEAKIAQ---LEEQVEQEAREKQAATKSLKQKD 1848

Query: 126  RAKRATIMSLED----FEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
            +  +  ++ +ED     EQ   QA + NA ++    + E   E  QR+    R L++EL
Sbjct: 1849 KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1907



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 48/213 (22%), Positives = 90/213 (42%), Gaps = 26/213 (12%)

Query: 2    EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEEL------REFQEGSREYEAELETQLQ 55
            E  GK     ++ A+    L  T +   E T+++L      R+ +E     + +L+ +++
Sbjct: 1298 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME 1357

Query: 56   QIETRNRDL------LSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQ 109
              +   R +      LS++ +   +  +  E  E       ++I  L     +  A  D+
Sbjct: 1358 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1417

Query: 110  LQKYIRELEQANDDLE---RAKRATIMSLEDFEQRLNQ--AIERNAF---------LESE 155
            L+K    L+Q  DDL      +R  + +LE  +++ +Q  A E+N            E+E
Sbjct: 1418 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1477

Query: 156  LDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
              EKE    S+ R  +EA + ++EL    K  K
Sbjct: 1478 AREKETKALSLARALEEALEAKEELERTNKMLK 1510



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 51/204 (25%), Positives = 91/204 (44%), Gaps = 29/204 (14%)

Query: 1    MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
            + D     + EEE+A     L   ++      +  L++ +E SR+   ELE   +++E  
Sbjct: 1008 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK-EEKSRQ---ELEKLKRKLEGD 1063

Query: 61   NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
              D   +   L+ ++  +K +   +  E    ++ L+D++AQ    K+   K IRELE  
Sbjct: 1064 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ----KNNALKKIRELEGH 1119

Query: 121  NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
              DL+          ED +       ER A  ++E  +K +L E ++ LK E  D     
Sbjct: 1120 ISDLQ----------EDLDS------ERAARNKAE-KQKRDLGEELEALKTELEDTLDST 1162

Query: 181  AVQQ----KQEKPRTPMPSSVEAE 200
            A QQ    K+E+  T +  +++ E
Sbjct: 1163 ATQQELRAKREQEVTVLKKALDEE 1186



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 38/175 (21%), Positives = 73/175 (41%), Gaps = 11/175 (6%)

Query: 21  LAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELET--- 77
           LA   ++R     + +  FQ   R Y A      +Q +     ++  N    ++L     
Sbjct: 775 LAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQW 834

Query: 78  ------IKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRAT 131
                 +K   +V   E   ++ A ED+L +TK  + + +  ++ELEQ +  L   K   
Sbjct: 835 WRLFTKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLL 892

Query: 132 IMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186
              L+   +   +A E    L ++  E E +L  ++   +E  D  Q+L  ++K+
Sbjct: 893 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 947



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 29/208 (13%)

Query: 1    MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
            +E + K   +E E+    KD         E ++  L    E  +    ELE +LQ  E  
Sbjct: 1502 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE-- 1559

Query: 61   NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
                     RL + ++ +K +FE       R + A ++   Q +  + QLQ+ + E E  
Sbjct: 1560 -----DAKLRLEVNMQALKGQFE-------RDLQARDE---QNEEKRRQLQRQLHEYETE 1604

Query: 121  NDDLERAKRATIMS--------LEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDE 172
             +D ER +RA   +        L+D E + + AI+       +L + +  ++  QR  ++
Sbjct: 1605 LED-ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1663

Query: 173  ARDLRQELAVQQKQEKPRTPMPSSVEAE 200
            AR  R E+    K+ + +     S+EA+
Sbjct: 1664 ARASRDEIFATAKENEKKA---KSLEAD 1688



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 49/224 (21%), Positives = 94/224 (41%), Gaps = 24/224 (10%)

Query: 4    SGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRN-- 61
            +G    +E +     KD+A    Q  ++TQE L   QE +R+ +  + T+L+Q+E     
Sbjct: 1293 TGMLNEAEGKAIKLAKDVASLSSQ-LQDTQELL---QEETRQ-KLNVSTKLRQLEEERNS 1347

Query: 62   -RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ- 119
             +D L E    +  LE       +Q S+  +++      +   +  K + QK I  L Q 
Sbjct: 1348 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1407

Query: 120  ------ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEA 173
                  A D LE+ K      L+D    L+   +  + LE +  + + LL   + +  + 
Sbjct: 1408 YEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKY 1467

Query: 174  RDLRQELAVQQKQEKPRT---------PMPSSVEAERTDTAVQA 208
             D R     + ++++ +           + +  E ERT+  ++A
Sbjct: 1468 ADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKA 1511



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 36/174 (20%), Positives = 78/174 (44%), Gaps = 18/174 (10%)

Query: 29   AENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMEL----------ETI 78
            AE  +  L   ++   E   E+E +L++ E R + L +E  ++  ++          E  
Sbjct: 906  AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 965

Query: 79   KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL------ERAKRATI 132
            ++K +++      +I  LED++       ++L K  + LE+   DL      E  K   +
Sbjct: 966  RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025

Query: 133  MSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186
              L++  + +   +E    L+ E   ++ L +  ++L+ +A D  +++A  Q Q
Sbjct: 1026 TKLKNKHESMISELE--VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1077



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 41/203 (20%), Positives = 90/203 (44%), Gaps = 14/203 (6%)

Query: 1    MEDS-GKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIET 59
            +ED+   T + +E  A   +++ +  K   E T+    + QE  +++   +E   +Q+E 
Sbjct: 1155 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE- 1213

Query: 60   RNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ 119
                   +  R +  L+  K+  E ++++   ++  L     + +  K +L+  ++EL+ 
Sbjct: 1214 -------QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS 1266

Query: 120  ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKE-NLLESVQRLKDEARDLRQ 178
               D ERA+      L D   +L   +E    + +E + K   L + V  L  + +D ++
Sbjct: 1267 KCSDGERAR----AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1322

Query: 179  ELAVQQKQEKPRTPMPSSVEAER 201
             L  + +Q+   +     +E ER
Sbjct: 1323 LLQEETRQKLNVSTKLRQLEEER 1345



 Score = 36.6 bits (83), Expect = 0.032
 Identities = 47/233 (20%), Positives = 87/233 (37%), Gaps = 20/233 (8%)

Query: 19   KDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETI 78
            + L    +++     + L E +  S +Y  E +    +   +    LS    L   LE  
Sbjct: 1440 RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA- 1498

Query: 79   KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDF 138
            KE+ E  +    + + A  +DL  +K   D + K + ELE++   LE         LE+ 
Sbjct: 1499 KEELERTN----KMLKAEMEDLVSSK---DDVGKNVHELEKSKRALETQMEEMKTQLEEL 1551

Query: 139  EQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQ------------ELAVQQKQ 186
            E  L    +    LE  +   +   E   + +DE  + ++            EL  ++KQ
Sbjct: 1552 EDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ 1611

Query: 187  EKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDS 239
                      +E +  D  +QA  ++     A +           F+R L+D+
Sbjct: 1612 RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1664



 Score = 36.2 bits (82), Expect = 0.042
 Identities = 41/195 (21%), Positives = 86/195 (44%), Gaps = 22/195 (11%)

Query: 31   NTQEELREFQEGSREYEAELETQL---QQIETRNRDLLSENNRLRMELETIKEKFEVQH- 86
            N  +++RE +    + + +L+++     + E + RDL  E   L+ ELE   +    Q  
Sbjct: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167

Query: 87   --SEGYRQISAL-----EDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFE 139
              ++  ++++ L     E+  +    +++  QK+ + +E+  + LE+ KRA   +L+  +
Sbjct: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA-NLDKNK 1226

Query: 140  QRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEA 199
            Q L +    NA L  EL         + + K E    +++L  Q ++ + +        A
Sbjct: 1227 QTLEK---ENADLAGEL-------RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1276

Query: 200  ERTDTAVQATGSVPS 214
            E  D   +    V S
Sbjct: 1277 ELNDKVHKLQNEVES 1291



 Score = 35.4 bits (80), Expect = 0.072
 Identities = 35/187 (18%), Positives = 87/187 (46%), Gaps = 10/187 (5%)

Query: 1    MEDSGKTFSSEEEE-ANYWKDLAMTYKQRAENTQEELREFQEG---SREYEAELETQLQQ 56
            +E+  K F  E E     +++ A  Y  + E T+  L++  +      + + +L + L++
Sbjct: 1390 LEEGKKRFQKEIENLTQQYEEKAAAY-DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1448

Query: 57   IETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRE 116
             + +   LL+E   +  +    +++ E +  E   +  +L   L +    K++L++  + 
Sbjct: 1449 KQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKM 1508

Query: 117  LEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDL 176
            L+   +DL  +K     ++ + E+       +   ++++L+E E+ L++ +  K     L
Sbjct: 1509 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAK-----L 1563

Query: 177  RQELAVQ 183
            R E+ +Q
Sbjct: 1564 RLEVNMQ 1570



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 33/163 (20%), Positives = 69/163 (42%), Gaps = 27/163 (16%)

Query: 28  RAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHS 87
           R E   +   +  + ++E + + E +L+++E ++  L  E N L+ +L+   E +     
Sbjct: 849 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY----- 903

Query: 88  EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQ-AI 146
                 +  E+   +  A K +L++ + E+E                LE+ E R  Q   
Sbjct: 904 ------AEAEEMRVRLAAKKQELEEILHEMEAR--------------LEEEEDRGQQLQA 943

Query: 147 ERNAFLESELDEKENL-LESVQRLKDEARDLRQELAVQQKQEK 188
           ER    +  LD +E L  E   R K +   +  E  +++ +++
Sbjct: 944 ERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 986



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 18/77 (23%), Positives = 34/77 (44%)

Query: 1    MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
            +ED  K     +E+A          K++ E  +EE +      R+ + EL+   +  E  
Sbjct: 1858 VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAM 1917

Query: 61   NRDLLSENNRLRMELET 77
             R++ +  ++LR   ET
Sbjct: 1918 GREVNALKSKLRRGNET 1934



 Score = 28.5 bits (62), Expect = 8.8
 Identities = 31/146 (21%), Positives = 66/146 (45%), Gaps = 13/146 (8%)

Query: 27   QRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQH 86
            Q  E  ++E RE Q  ++         L+Q + + +++L +    R   E  KE+ E  +
Sbjct: 1825 QLEEQVEQEAREKQAATKS--------LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1876

Query: 87   SEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAI 146
            +   +    LE+   +++ I    +K  REL++A +  E   R  + +L+   +R N+  
Sbjct: 1877 ARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGR-EVNALKSKLRRGNE-- 1933

Query: 147  ERNAFLESELDEKENLLESVQRLKDE 172
               +F+ S       ++E+    ++E
Sbjct: 1934 --TSFVPSRRSGGRRVIENADGSEEE 1957


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 46/196 (23%), Positives = 86/196 (43%), Gaps = 6/196 (3%)

Query: 12   EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL 71
            +EE    +      +Q+     EEL E  E  +  +A L+   Q +E  N DL  E   L
Sbjct: 1191 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1250

Query: 72   ---RMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128
               + E+E  K+K E Q  E   + S  E   A+   + D++ K   E+E     L  A+
Sbjct: 1251 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVTGMLNEAE 1307

Query: 129  RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
               I   +D     +Q  +    L+ E  +K N+   +++L++E   L+ +L  + + ++
Sbjct: 1308 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1367

Query: 189  PRTPMPSSVEAERTDT 204
                  S++  + +D+
Sbjct: 1368 NLERHISTLNIQLSDS 1383



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 44/199 (22%), Positives = 92/199 (46%), Gaps = 22/199 (11%)

Query: 11   EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70
            +EEE    +D     K+R +  + EL+E ++   +   E     +Q++    +L +E   
Sbjct: 857  QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEE 915

Query: 71   LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR- 129
            +R+ L   K++ E    E   ++   ED   Q +A + ++ + + +LE+  ++ E A++ 
Sbjct: 916  MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 975

Query: 130  ---------ATIMSLED----FEQRLNQAIERNAFLE-------SELDEKENLLESVQRL 169
                     A I  LED     + + N+  +    LE       + L E+E   +++ +L
Sbjct: 976  LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKL 1035

Query: 170  KDEARDLRQELAVQQKQEK 188
            K++   +  EL V+ K+E+
Sbjct: 1036 KNKHESMISELEVRLKKEE 1054



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 48/179 (26%), Positives = 83/179 (46%), Gaps = 26/179 (14%)

Query: 11   EEEEANY--WKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSEN 68
            EEE+ N     D      Q+AE    EL       R    + E+  QQ+E +N++L S+ 
Sbjct: 1753 EEEQGNMEAMSDRVRKATQQAEQLSNELAT----ERSTAQKNESARQQLERQNKELRSKL 1808

Query: 69   NRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL---E 125
            + +      +K KF+         I+ALE  +AQ   +++Q+++  RE + A   L   +
Sbjct: 1809 HEME---GAVKSKFK-------STIAALEAKIAQ---LEEQVEQEAREKQAATKSLKQKD 1855

Query: 126  RAKRATIMSLED----FEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
            +  +  ++ +ED     EQ   QA + NA ++    + E   E  QR+    R L++EL
Sbjct: 1856 KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1914



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 48/213 (22%), Positives = 90/213 (42%), Gaps = 26/213 (12%)

Query: 2    EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEEL------REFQEGSREYEAELETQLQ 55
            E  GK     ++ A+    L  T +   E T+++L      R+ +E     + +L+ +++
Sbjct: 1305 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME 1364

Query: 56   QIETRNRDL------LSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQ 109
              +   R +      LS++ +   +  +  E  E       ++I  L     +  A  D+
Sbjct: 1365 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1424

Query: 110  LQKYIRELEQANDDLE---RAKRATIMSLEDFEQRLNQ--AIERNAF---------LESE 155
            L+K    L+Q  DDL      +R  + +LE  +++ +Q  A E+N            E+E
Sbjct: 1425 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1484

Query: 156  LDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
              EKE    S+ R  +EA + ++EL    K  K
Sbjct: 1485 AREKETKALSLARALEEALEAKEELERTNKMLK 1517



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 51/204 (25%), Positives = 91/204 (44%), Gaps = 29/204 (14%)

Query: 1    MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
            + D     + EEE+A     L   ++      +  L++ +E SR+   ELE   +++E  
Sbjct: 1015 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK-EEKSRQ---ELEKLKRKLEGD 1070

Query: 61   NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
              D   +   L+ ++  +K +   +  E    ++ L+D++AQ    K+   K IRELE  
Sbjct: 1071 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ----KNNALKKIRELEGH 1126

Query: 121  NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
              DL+          ED +       ER A  ++E  +K +L E ++ LK E  D     
Sbjct: 1127 ISDLQ----------EDLDS------ERAARNKAE-KQKRDLGEELEALKTELEDTLDST 1169

Query: 181  AVQQ----KQEKPRTPMPSSVEAE 200
            A QQ    K+E+  T +  +++ E
Sbjct: 1170 ATQQELRAKREQEVTVLKKALDEE 1193



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 38/175 (21%), Positives = 73/175 (41%), Gaps = 11/175 (6%)

Query: 21  LAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELET--- 77
           LA   ++R     + +  FQ   R Y A      +Q +     ++  N    ++L     
Sbjct: 782 LAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQW 841

Query: 78  ------IKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRAT 131
                 +K   +V   E   ++ A ED+L +TK  + + +  ++ELEQ +  L   K   
Sbjct: 842 WRLFTKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLL 899

Query: 132 IMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186
              L+   +   +A E    L ++  E E +L  ++   +E  D  Q+L  ++K+
Sbjct: 900 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 954



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 29/208 (13%)

Query: 1    MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
            +E + K   +E E+    KD         E ++  L    E  +    ELE +LQ  E  
Sbjct: 1509 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE-- 1566

Query: 61   NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
                     RL + ++ +K +FE       R + A ++   Q +  + QLQ+ + E E  
Sbjct: 1567 -----DAKLRLEVNMQALKGQFE-------RDLQARDE---QNEEKRRQLQRQLHEYETE 1611

Query: 121  NDDLERAKRATIMS--------LEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDE 172
             +D ER +RA   +        L+D E + + AI+       +L + +  ++  QR  ++
Sbjct: 1612 LED-ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1670

Query: 173  ARDLRQELAVQQKQEKPRTPMPSSVEAE 200
            AR  R E+    K+ + +     S+EA+
Sbjct: 1671 ARASRDEIFATAKENEKKA---KSLEAD 1695



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 49/224 (21%), Positives = 94/224 (41%), Gaps = 24/224 (10%)

Query: 4    SGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRN-- 61
            +G    +E +     KD+A    Q  ++TQE L   QE +R+ +  + T+L+Q+E     
Sbjct: 1300 TGMLNEAEGKAIKLAKDVASLSSQ-LQDTQELL---QEETRQ-KLNVSTKLRQLEEERNS 1354

Query: 62   -RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ- 119
             +D L E    +  LE       +Q S+  +++      +   +  K + QK I  L Q 
Sbjct: 1355 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1414

Query: 120  ------ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEA 173
                  A D LE+ K      L+D    L+   +  + LE +  + + LL   + +  + 
Sbjct: 1415 YEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKY 1474

Query: 174  RDLRQELAVQQKQEKPRT---------PMPSSVEAERTDTAVQA 208
             D R     + ++++ +           + +  E ERT+  ++A
Sbjct: 1475 ADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKA 1518



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 36/174 (20%), Positives = 78/174 (44%), Gaps = 18/174 (10%)

Query: 29   AENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMEL----------ETI 78
            AE  +  L   ++   E   E+E +L++ E R + L +E  ++  ++          E  
Sbjct: 913  AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 972

Query: 79   KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL------ERAKRATI 132
            ++K +++      +I  LED++       ++L K  + LE+   DL      E  K   +
Sbjct: 973  RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032

Query: 133  MSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186
              L++  + +   +E    L+ E   ++ L +  ++L+ +A D  +++A  Q Q
Sbjct: 1033 TKLKNKHESMISELE--VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1084



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 41/203 (20%), Positives = 90/203 (44%), Gaps = 14/203 (6%)

Query: 1    MEDS-GKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIET 59
            +ED+   T + +E  A   +++ +  K   E T+    + QE  +++   +E   +Q+E 
Sbjct: 1162 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE- 1220

Query: 60   RNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ 119
                   +  R +  L+  K+  E ++++   ++  L     + +  K +L+  ++EL+ 
Sbjct: 1221 -------QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS 1273

Query: 120  ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKE-NLLESVQRLKDEARDLRQ 178
               D ERA+      L D   +L   +E    + +E + K   L + V  L  + +D ++
Sbjct: 1274 KCSDGERAR----AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1329

Query: 179  ELAVQQKQEKPRTPMPSSVEAER 201
             L  + +Q+   +     +E ER
Sbjct: 1330 LLQEETRQKLNVSTKLRQLEEER 1352



 Score = 36.6 bits (83), Expect = 0.032
 Identities = 47/233 (20%), Positives = 87/233 (37%), Gaps = 20/233 (8%)

Query: 19   KDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETI 78
            + L    +++     + L E +  S +Y  E +    +   +    LS    L   LE  
Sbjct: 1447 RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA- 1505

Query: 79   KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDF 138
            KE+ E  +    + + A  +DL  +K   D + K + ELE++   LE         LE+ 
Sbjct: 1506 KEELERTN----KMLKAEMEDLVSSK---DDVGKNVHELEKSKRALETQMEEMKTQLEEL 1558

Query: 139  EQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQ------------ELAVQQKQ 186
            E  L    +    LE  +   +   E   + +DE  + ++            EL  ++KQ
Sbjct: 1559 EDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ 1618

Query: 187  EKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDS 239
                      +E +  D  +QA  ++     A +           F+R L+D+
Sbjct: 1619 RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1671



 Score = 36.2 bits (82), Expect = 0.042
 Identities = 41/195 (21%), Positives = 86/195 (44%), Gaps = 22/195 (11%)

Query: 31   NTQEELREFQEGSREYEAELETQL---QQIETRNRDLLSENNRLRMELETIKEKFEVQH- 86
            N  +++RE +    + + +L+++     + E + RDL  E   L+ ELE   +    Q  
Sbjct: 1115 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1174

Query: 87   --SEGYRQISAL-----EDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFE 139
              ++  ++++ L     E+  +    +++  QK+ + +E+  + LE+ KRA   +L+  +
Sbjct: 1175 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA-NLDKNK 1233

Query: 140  QRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEA 199
            Q L +    NA L  EL         + + K E    +++L  Q ++ + +        A
Sbjct: 1234 QTLEK---ENADLAGEL-------RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1283

Query: 200  ERTDTAVQATGSVPS 214
            E  D   +    V S
Sbjct: 1284 ELNDKVHKLQNEVES 1298



 Score = 35.4 bits (80), Expect = 0.072
 Identities = 35/187 (18%), Positives = 87/187 (46%), Gaps = 10/187 (5%)

Query: 1    MEDSGKTFSSEEEE-ANYWKDLAMTYKQRAENTQEELREFQEG---SREYEAELETQLQQ 56
            +E+  K F  E E     +++ A  Y  + E T+  L++  +      + + +L + L++
Sbjct: 1397 LEEGKKRFQKEIENLTQQYEEKAAAY-DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1455

Query: 57   IETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRE 116
             + +   LL+E   +  +    +++ E +  E   +  +L   L +    K++L++  + 
Sbjct: 1456 KQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKM 1515

Query: 117  LEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDL 176
            L+   +DL  +K     ++ + E+       +   ++++L+E E+ L++ +  K     L
Sbjct: 1516 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAK-----L 1570

Query: 177  RQELAVQ 183
            R E+ +Q
Sbjct: 1571 RLEVNMQ 1577



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 33/163 (20%), Positives = 69/163 (42%), Gaps = 27/163 (16%)

Query: 28  RAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHS 87
           R E   +   +  + ++E + + E +L+++E ++  L  E N L+ +L+   E +     
Sbjct: 856 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY----- 910

Query: 88  EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQ-AI 146
                 +  E+   +  A K +L++ + E+E                LE+ E R  Q   
Sbjct: 911 ------AEAEEMRVRLAAKKQELEEILHEMEAR--------------LEEEEDRGQQLQA 950

Query: 147 ERNAFLESELDEKENL-LESVQRLKDEARDLRQELAVQQKQEK 188
           ER    +  LD +E L  E   R K +   +  E  +++ +++
Sbjct: 951 ERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 993



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 18/77 (23%), Positives = 34/77 (44%)

Query: 1    MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
            +ED  K     +E+A          K++ E  +EE +      R+ + EL+   +  E  
Sbjct: 1865 VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAM 1924

Query: 61   NRDLLSENNRLRMELET 77
             R++ +  ++LR   ET
Sbjct: 1925 GREVNALKSKLRRGNET 1941



 Score = 28.5 bits (62), Expect = 8.8
 Identities = 31/146 (21%), Positives = 66/146 (45%), Gaps = 13/146 (8%)

Query: 27   QRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQH 86
            Q  E  ++E RE Q  ++         L+Q + + +++L +    R   E  KE+ E  +
Sbjct: 1832 QLEEQVEQEAREKQAATKS--------LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1883

Query: 87   SEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAI 146
            +   +    LE+   +++ I    +K  REL++A +  E   R  + +L+   +R N+  
Sbjct: 1884 ARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGR-EVNALKSKLRRGNE-- 1940

Query: 147  ERNAFLESELDEKENLLESVQRLKDE 172
               +F+ S       ++E+    ++E
Sbjct: 1941 --TSFVPSRRSGGRRVIENADGSEEE 1964


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 46/196 (23%), Positives = 86/196 (43%), Gaps = 6/196 (3%)

Query: 12   EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL 71
            +EE    +      +Q+     EEL E  E  +  +A L+   Q +E  N DL  E   L
Sbjct: 1191 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1250

Query: 72   ---RMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128
               + E+E  K+K E Q  E   + S  E   A+   + D++ K   E+E     L  A+
Sbjct: 1251 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVTGMLNEAE 1307

Query: 129  RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
               I   +D     +Q  +    L+ E  +K N+   +++L++E   L+ +L  + + ++
Sbjct: 1308 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1367

Query: 189  PRTPMPSSVEAERTDT 204
                  S++  + +D+
Sbjct: 1368 NLERHISTLNIQLSDS 1383



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 44/199 (22%), Positives = 92/199 (46%), Gaps = 22/199 (11%)

Query: 11   EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70
            +EEE    +D     K+R +  + EL+E ++   +   E     +Q++    +L +E   
Sbjct: 857  QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEE 915

Query: 71   LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR- 129
            +R+ L   K++ E    E   ++   ED   Q +A + ++ + + +LE+  ++ E A++ 
Sbjct: 916  MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 975

Query: 130  ---------ATIMSLED----FEQRLNQAIERNAFLE-------SELDEKENLLESVQRL 169
                     A I  LED     + + N+  +    LE       + L E+E   +++ +L
Sbjct: 976  LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKL 1035

Query: 170  KDEARDLRQELAVQQKQEK 188
            K++   +  EL V+ K+E+
Sbjct: 1036 KNKHESMISELEVRLKKEE 1054



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 48/179 (26%), Positives = 83/179 (46%), Gaps = 26/179 (14%)

Query: 11   EEEEANY--WKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSEN 68
            EEE+ N     D      Q+AE    EL       R    + E+  QQ+E +N++L S+ 
Sbjct: 1753 EEEQGNMEAMSDRVRKATQQAEQLSNELAT----ERSTAQKNESARQQLERQNKELRSKL 1808

Query: 69   NRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL---E 125
            + +      +K KF+         I+ALE  +AQ   +++Q+++  RE + A   L   +
Sbjct: 1809 HEME---GAVKSKFK-------STIAALEAKIAQ---LEEQVEQEAREKQAATKSLKQKD 1855

Query: 126  RAKRATIMSLED----FEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
            +  +  ++ +ED     EQ   QA + NA ++    + E   E  QR+    R L++EL
Sbjct: 1856 KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1914



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 48/213 (22%), Positives = 90/213 (42%), Gaps = 26/213 (12%)

Query: 2    EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEEL------REFQEGSREYEAELETQLQ 55
            E  GK     ++ A+    L  T +   E T+++L      R+ +E     + +L+ +++
Sbjct: 1305 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME 1364

Query: 56   QIETRNRDL------LSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQ 109
              +   R +      LS++ +   +  +  E  E       ++I  L     +  A  D+
Sbjct: 1365 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1424

Query: 110  LQKYIRELEQANDDLE---RAKRATIMSLEDFEQRLNQ--AIERNAF---------LESE 155
            L+K    L+Q  DDL      +R  + +LE  +++ +Q  A E+N            E+E
Sbjct: 1425 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1484

Query: 156  LDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
              EKE    S+ R  +EA + ++EL    K  K
Sbjct: 1485 AREKETKALSLARALEEALEAKEELERTNKMLK 1517



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 51/204 (25%), Positives = 91/204 (44%), Gaps = 29/204 (14%)

Query: 1    MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
            + D     + EEE+A     L   ++      +  L++ +E SR+   ELE   +++E  
Sbjct: 1015 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK-EEKSRQ---ELEKLKRKLEGD 1070

Query: 61   NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
              D   +   L+ ++  +K +   +  E    ++ L+D++AQ    K+   K IRELE  
Sbjct: 1071 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ----KNNALKKIRELEGH 1126

Query: 121  NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
              DL+          ED +       ER A  ++E  +K +L E ++ LK E  D     
Sbjct: 1127 ISDLQ----------EDLDS------ERAARNKAE-KQKRDLGEELEALKTELEDTLDST 1169

Query: 181  AVQQ----KQEKPRTPMPSSVEAE 200
            A QQ    K+E+  T +  +++ E
Sbjct: 1170 ATQQELRAKREQEVTVLKKALDEE 1193



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 38/175 (21%), Positives = 73/175 (41%), Gaps = 11/175 (6%)

Query: 21  LAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELET--- 77
           LA   ++R     + +  FQ   R Y A      +Q +     ++  N    ++L     
Sbjct: 782 LAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQW 841

Query: 78  ------IKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRAT 131
                 +K   +V   E   ++ A ED+L +TK  + + +  ++ELEQ +  L   K   
Sbjct: 842 WRLFTKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLL 899

Query: 132 IMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186
              L+   +   +A E    L ++  E E +L  ++   +E  D  Q+L  ++K+
Sbjct: 900 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 954



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 29/208 (13%)

Query: 1    MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
            +E + K   +E E+    KD         E ++  L    E  +    ELE +LQ  E  
Sbjct: 1509 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE-- 1566

Query: 61   NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
                     RL + ++ +K +FE       R + A ++   Q +  + QLQ+ + E E  
Sbjct: 1567 -----DAKLRLEVNMQALKGQFE-------RDLQARDE---QNEEKRRQLQRQLHEYETE 1611

Query: 121  NDDLERAKRATIMS--------LEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDE 172
             +D ER +RA   +        L+D E + + AI+       +L + +  ++  QR  ++
Sbjct: 1612 LED-ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1670

Query: 173  ARDLRQELAVQQKQEKPRTPMPSSVEAE 200
            AR  R E+    K+ + +     S+EA+
Sbjct: 1671 ARASRDEIFATAKENEKKA---KSLEAD 1695



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 49/224 (21%), Positives = 94/224 (41%), Gaps = 24/224 (10%)

Query: 4    SGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRN-- 61
            +G    +E +     KD+A    Q  ++TQE L   QE +R+ +  + T+L+Q+E     
Sbjct: 1300 TGMLNEAEGKAIKLAKDVASLSSQ-LQDTQELL---QEETRQ-KLNVSTKLRQLEEERNS 1354

Query: 62   -RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ- 119
             +D L E    +  LE       +Q S+  +++      +   +  K + QK I  L Q 
Sbjct: 1355 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1414

Query: 120  ------ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEA 173
                  A D LE+ K      L+D    L+   +  + LE +  + + LL   + +  + 
Sbjct: 1415 YEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKY 1474

Query: 174  RDLRQELAVQQKQEKPRT---------PMPSSVEAERTDTAVQA 208
             D R     + ++++ +           + +  E ERT+  ++A
Sbjct: 1475 ADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKA 1518



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 36/174 (20%), Positives = 78/174 (44%), Gaps = 18/174 (10%)

Query: 29   AENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMEL----------ETI 78
            AE  +  L   ++   E   E+E +L++ E R + L +E  ++  ++          E  
Sbjct: 913  AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 972

Query: 79   KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL------ERAKRATI 132
            ++K +++      +I  LED++       ++L K  + LE+   DL      E  K   +
Sbjct: 973  RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1032

Query: 133  MSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186
              L++  + +   +E    L+ E   ++ L +  ++L+ +A D  +++A  Q Q
Sbjct: 1033 TKLKNKHESMISELE--VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1084



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 41/203 (20%), Positives = 90/203 (44%), Gaps = 14/203 (6%)

Query: 1    MEDS-GKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIET 59
            +ED+   T + +E  A   +++ +  K   E T+    + QE  +++   +E   +Q+E 
Sbjct: 1162 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE- 1220

Query: 60   RNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ 119
                   +  R +  L+  K+  E ++++   ++  L     + +  K +L+  ++EL+ 
Sbjct: 1221 -------QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS 1273

Query: 120  ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKE-NLLESVQRLKDEARDLRQ 178
               D ERA+      L D   +L   +E    + +E + K   L + V  L  + +D ++
Sbjct: 1274 KCSDGERAR----AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1329

Query: 179  ELAVQQKQEKPRTPMPSSVEAER 201
             L  + +Q+   +     +E ER
Sbjct: 1330 LLQEETRQKLNVSTKLRQLEEER 1352



 Score = 36.6 bits (83), Expect = 0.032
 Identities = 47/233 (20%), Positives = 87/233 (37%), Gaps = 20/233 (8%)

Query: 19   KDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETI 78
            + L    +++     + L E +  S +Y  E +    +   +    LS    L   LE  
Sbjct: 1447 RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA- 1505

Query: 79   KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDF 138
            KE+ E  +    + + A  +DL  +K   D + K + ELE++   LE         LE+ 
Sbjct: 1506 KEELERTN----KMLKAEMEDLVSSK---DDVGKNVHELEKSKRALETQMEEMKTQLEEL 1558

Query: 139  EQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQ------------ELAVQQKQ 186
            E  L    +    LE  +   +   E   + +DE  + ++            EL  ++KQ
Sbjct: 1559 EDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ 1618

Query: 187  EKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDS 239
                      +E +  D  +QA  ++     A +           F+R L+D+
Sbjct: 1619 RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1671



 Score = 36.2 bits (82), Expect = 0.042
 Identities = 41/195 (21%), Positives = 86/195 (44%), Gaps = 22/195 (11%)

Query: 31   NTQEELREFQEGSREYEAELETQL---QQIETRNRDLLSENNRLRMELETIKEKFEVQH- 86
            N  +++RE +    + + +L+++     + E + RDL  E   L+ ELE   +    Q  
Sbjct: 1115 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1174

Query: 87   --SEGYRQISAL-----EDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFE 139
              ++  ++++ L     E+  +    +++  QK+ + +E+  + LE+ KRA   +L+  +
Sbjct: 1175 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA-NLDKNK 1233

Query: 140  QRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEA 199
            Q L +    NA L  EL         + + K E    +++L  Q ++ + +        A
Sbjct: 1234 QTLEK---ENADLAGEL-------RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1283

Query: 200  ERTDTAVQATGSVPS 214
            E  D   +    V S
Sbjct: 1284 ELNDKVHKLQNEVES 1298



 Score = 35.4 bits (80), Expect = 0.072
 Identities = 35/187 (18%), Positives = 87/187 (46%), Gaps = 10/187 (5%)

Query: 1    MEDSGKTFSSEEEE-ANYWKDLAMTYKQRAENTQEELREFQEG---SREYEAELETQLQQ 56
            +E+  K F  E E     +++ A  Y  + E T+  L++  +      + + +L + L++
Sbjct: 1397 LEEGKKRFQKEIENLTQQYEEKAAAY-DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1455

Query: 57   IETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRE 116
             + +   LL+E   +  +    +++ E +  E   +  +L   L +    K++L++  + 
Sbjct: 1456 KQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKM 1515

Query: 117  LEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDL 176
            L+   +DL  +K     ++ + E+       +   ++++L+E E+ L++ +  K     L
Sbjct: 1516 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAK-----L 1570

Query: 177  RQELAVQ 183
            R E+ +Q
Sbjct: 1571 RLEVNMQ 1577



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 33/163 (20%), Positives = 69/163 (42%), Gaps = 27/163 (16%)

Query: 28  RAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHS 87
           R E   +   +  + ++E + + E +L+++E ++  L  E N L+ +L+   E +     
Sbjct: 856 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY----- 910

Query: 88  EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQ-AI 146
                 +  E+   +  A K +L++ + E+E                LE+ E R  Q   
Sbjct: 911 ------AEAEEMRVRLAAKKQELEEILHEMEAR--------------LEEEEDRGQQLQA 950

Query: 147 ERNAFLESELDEKENL-LESVQRLKDEARDLRQELAVQQKQEK 188
           ER    +  LD +E L  E   R K +   +  E  +++ +++
Sbjct: 951 ERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 993



 Score = 28.9 bits (63), Expect = 6.8
 Identities = 16/72 (22%), Positives = 32/72 (44%)

Query: 1    MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
            +ED  K     +E+A          K++ E  +EE +      R+ + EL+   +  E  
Sbjct: 1865 VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAM 1924

Query: 61   NRDLLSENNRLR 72
             R++ +  ++LR
Sbjct: 1925 GREVNALKSKLR 1936



 Score = 28.5 bits (62), Expect = 8.8
 Identities = 24/107 (22%), Positives = 51/107 (47%), Gaps = 11/107 (10%)

Query: 27   QRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQH 86
            Q  E  ++E RE Q  ++         L+Q + + +++L +    R   E  KE+ E  +
Sbjct: 1832 QLEEQVEQEAREKQAATKS--------LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1883

Query: 87   S---EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRA 130
            +   +  RQ+   E++  +  A + +LQ+ + E  ++N+ + R   A
Sbjct: 1884 ARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA 1930


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 46/196 (23%), Positives = 86/196 (43%), Gaps = 6/196 (3%)

Query: 12   EEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL 71
            +EE    +      +Q+     EEL E  E  +  +A L+   Q +E  N DL  E   L
Sbjct: 1184 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1243

Query: 72   ---RMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAK 128
               + E+E  K+K E Q  E   + S  E   A+   + D++ K   E+E     L  A+
Sbjct: 1244 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVTGMLNEAE 1300

Query: 129  RATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
               I   +D     +Q  +    L+ E  +K N+   +++L++E   L+ +L  + + ++
Sbjct: 1301 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1360

Query: 189  PRTPMPSSVEAERTDT 204
                  S++  + +D+
Sbjct: 1361 NLERHISTLNIQLSDS 1376



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 44/199 (22%), Positives = 92/199 (46%), Gaps = 22/199 (11%)

Query: 11   EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNR 70
            +EEE    +D     K+R +  + EL+E ++   +   E     +Q++    +L +E   
Sbjct: 850  QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEE 908

Query: 71   LRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKR- 129
            +R+ L   K++ E    E   ++   ED   Q +A + ++ + + +LE+  ++ E A++ 
Sbjct: 909  MRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQK 968

Query: 130  ---------ATIMSLED----FEQRLNQAIERNAFLE-------SELDEKENLLESVQRL 169
                     A I  LED     + + N+  +    LE       + L E+E   +++ +L
Sbjct: 969  LQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKL 1028

Query: 170  KDEARDLRQELAVQQKQEK 188
            K++   +  EL V+ K+E+
Sbjct: 1029 KNKHESMISELEVRLKKEE 1047



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 48/179 (26%), Positives = 83/179 (46%), Gaps = 26/179 (14%)

Query: 11   EEEEANY--WKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSEN 68
            EEE+ N     D      Q+AE    EL       R    + E+  QQ+E +N++L S+ 
Sbjct: 1746 EEEQGNMEAMSDRVRKATQQAEQLSNELAT----ERSTAQKNESARQQLERQNKELRSKL 1801

Query: 69   NRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL---E 125
            + +      +K KF+         I+ALE  +AQ   +++Q+++  RE + A   L   +
Sbjct: 1802 HEME---GAVKSKFK-------STIAALEAKIAQ---LEEQVEQEAREKQAATKSLKQKD 1848

Query: 126  RAKRATIMSLED----FEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
            +  +  ++ +ED     EQ   QA + NA ++    + E   E  QR+    R L++EL
Sbjct: 1849 KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1907



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 48/213 (22%), Positives = 90/213 (42%), Gaps = 26/213 (12%)

Query: 2    EDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEEL------REFQEGSREYEAELETQLQ 55
            E  GK     ++ A+    L  T +   E T+++L      R+ +E     + +L+ +++
Sbjct: 1298 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEME 1357

Query: 56   QIETRNRDL------LSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQ 109
              +   R +      LS++ +   +  +  E  E       ++I  L     +  A  D+
Sbjct: 1358 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK 1417

Query: 110  LQKYIRELEQANDDLE---RAKRATIMSLEDFEQRLNQ--AIERNAF---------LESE 155
            L+K    L+Q  DDL      +R  + +LE  +++ +Q  A E+N            E+E
Sbjct: 1418 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1477

Query: 156  LDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
              EKE    S+ R  +EA + ++EL    K  K
Sbjct: 1478 AREKETKALSLARALEEALEAKEELERTNKMLK 1510



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 51/204 (25%), Positives = 91/204 (44%), Gaps = 29/204 (14%)

Query: 1    MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
            + D     + EEE+A     L   ++      +  L++ +E SR+   ELE   +++E  
Sbjct: 1008 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK-EEKSRQ---ELEKLKRKLEGD 1063

Query: 61   NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
              D   +   L+ ++  +K +   +  E    ++ L+D++AQ    K+   K IRELE  
Sbjct: 1064 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQ----KNNALKKIRELEGH 1119

Query: 121  NDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQEL 180
              DL+          ED +       ER A  ++E  +K +L E ++ LK E  D     
Sbjct: 1120 ISDLQ----------EDLDS------ERAARNKAE-KQKRDLGEELEALKTELEDTLDST 1162

Query: 181  AVQQ----KQEKPRTPMPSSVEAE 200
            A QQ    K+E+  T +  +++ E
Sbjct: 1163 ATQQELRAKREQEVTVLKKALDEE 1186



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 38/175 (21%), Positives = 73/175 (41%), Gaps = 11/175 (6%)

Query: 21  LAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELET--- 77
           LA   ++R     + +  FQ   R Y A      +Q +     ++  N    ++L     
Sbjct: 775 LAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQW 834

Query: 78  ------IKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRAT 131
                 +K   +V   E   ++ A ED+L +TK  + + +  ++ELEQ +  L   K   
Sbjct: 835 WRLFTKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLL 892

Query: 132 IMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186
              L+   +   +A E    L ++  E E +L  ++   +E  D  Q+L  ++K+
Sbjct: 893 QEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 947



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 49/208 (23%), Positives = 89/208 (42%), Gaps = 29/208 (13%)

Query: 1    MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
            +E + K   +E E+    KD         E ++  L    E  +    ELE +LQ  E  
Sbjct: 1502 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE-- 1559

Query: 61   NRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQA 120
                     RL + ++ +K +FE       R + A ++   Q +  + QLQ+ + E E  
Sbjct: 1560 -----DAKLRLEVNMQALKGQFE-------RDLQARDE---QNEEKRRQLQRQLHEYETE 1604

Query: 121  NDDLERAKRATIMS--------LEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDE 172
             +D ER +RA   +        L+D E + + AI+       +L + +  ++  QR  ++
Sbjct: 1605 LED-ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1663

Query: 173  ARDLRQELAVQQKQEKPRTPMPSSVEAE 200
            AR  R E+    K+ + +     S+EA+
Sbjct: 1664 ARASRDEIFATAKENEKKA---KSLEAD 1688



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 49/224 (21%), Positives = 94/224 (41%), Gaps = 24/224 (10%)

Query: 4    SGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRN-- 61
            +G    +E +     KD+A    Q  ++TQE L   QE +R+ +  + T+L+Q+E     
Sbjct: 1293 TGMLNEAEGKAIKLAKDVASLSSQ-LQDTQELL---QEETRQ-KLNVSTKLRQLEEERNS 1347

Query: 62   -RDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ- 119
             +D L E    +  LE       +Q S+  +++      +   +  K + QK I  L Q 
Sbjct: 1348 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1407

Query: 120  ------ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEA 173
                  A D LE+ K      L+D    L+   +  + LE +  + + LL   + +  + 
Sbjct: 1408 YEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKY 1467

Query: 174  RDLRQELAVQQKQEKPRT---------PMPSSVEAERTDTAVQA 208
             D R     + ++++ +           + +  E ERT+  ++A
Sbjct: 1468 ADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKA 1511



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 36/174 (20%), Positives = 78/174 (44%), Gaps = 18/174 (10%)

Query: 29   AENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMEL----------ETI 78
            AE  +  L   ++   E   E+E +L++ E R + L +E  ++  ++          E  
Sbjct: 906  AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 965

Query: 79   KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL------ERAKRATI 132
            ++K +++      +I  LED++       ++L K  + LE+   DL      E  K   +
Sbjct: 966  RQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025

Query: 133  MSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQ 186
              L++  + +   +E    L+ E   ++ L +  ++L+ +A D  +++A  Q Q
Sbjct: 1026 TKLKNKHESMISELE--VRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1077



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 41/203 (20%), Positives = 90/203 (44%), Gaps = 14/203 (6%)

Query: 1    MEDS-GKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIET 59
            +ED+   T + +E  A   +++ +  K   E T+    + QE  +++   +E   +Q+E 
Sbjct: 1155 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLE- 1213

Query: 60   RNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQ 119
                   +  R +  L+  K+  E ++++   ++  L     + +  K +L+  ++EL+ 
Sbjct: 1214 -------QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS 1266

Query: 120  ANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKE-NLLESVQRLKDEARDLRQ 178
               D ERA+      L D   +L   +E    + +E + K   L + V  L  + +D ++
Sbjct: 1267 KCSDGERAR----AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1322

Query: 179  ELAVQQKQEKPRTPMPSSVEAER 201
             L  + +Q+   +     +E ER
Sbjct: 1323 LLQEETRQKLNVSTKLRQLEEER 1345



 Score = 36.6 bits (83), Expect = 0.032
 Identities = 47/233 (20%), Positives = 87/233 (37%), Gaps = 20/233 (8%)

Query: 19   KDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETI 78
            + L    +++     + L E +  S +Y  E +    +   +    LS    L   LE  
Sbjct: 1440 RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA- 1498

Query: 79   KEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDF 138
            KE+ E  +    + + A  +DL  +K   D + K + ELE++   LE         LE+ 
Sbjct: 1499 KEELERTN----KMLKAEMEDLVSSK---DDVGKNVHELEKSKRALETQMEEMKTQLEEL 1551

Query: 139  EQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQ------------ELAVQQKQ 186
            E  L    +    LE  +   +   E   + +DE  + ++            EL  ++KQ
Sbjct: 1552 EDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ 1611

Query: 187  EKPRTPMPSSVEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDS 239
                      +E +  D  +QA  ++     A +           F+R L+D+
Sbjct: 1612 RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1664



 Score = 36.2 bits (82), Expect = 0.042
 Identities = 41/195 (21%), Positives = 86/195 (44%), Gaps = 22/195 (11%)

Query: 31   NTQEELREFQEGSREYEAELETQL---QQIETRNRDLLSENNRLRMELETIKEKFEVQH- 86
            N  +++RE +    + + +L+++     + E + RDL  E   L+ ELE   +    Q  
Sbjct: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167

Query: 87   --SEGYRQISAL-----EDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFE 139
              ++  ++++ L     E+  +    +++  QK+ + +E+  + LE+ KRA   +L+  +
Sbjct: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA-NLDKNK 1226

Query: 140  QRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQKQEKPRTPMPSSVEA 199
            Q L +    NA L  EL         + + K E    +++L  Q ++ + +        A
Sbjct: 1227 QTLEK---ENADLAGEL-------RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 1276

Query: 200  ERTDTAVQATGSVPS 214
            E  D   +    V S
Sbjct: 1277 ELNDKVHKLQNEVES 1291



 Score = 35.4 bits (80), Expect = 0.072
 Identities = 35/187 (18%), Positives = 87/187 (46%), Gaps = 10/187 (5%)

Query: 1    MEDSGKTFSSEEEE-ANYWKDLAMTYKQRAENTQEELREFQEG---SREYEAELETQLQQ 56
            +E+  K F  E E     +++ A  Y  + E T+  L++  +      + + +L + L++
Sbjct: 1390 LEEGKKRFQKEIENLTQQYEEKAAAY-DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK 1448

Query: 57   IETRNRDLLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRE 116
             + +   LL+E   +  +    +++ E +  E   +  +L   L +    K++L++  + 
Sbjct: 1449 KQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKM 1508

Query: 117  LEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDL 176
            L+   +DL  +K     ++ + E+       +   ++++L+E E+ L++ +  K     L
Sbjct: 1509 LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAK-----L 1563

Query: 177  RQELAVQ 183
            R E+ +Q
Sbjct: 1564 RLEVNMQ 1570



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 33/163 (20%), Positives = 69/163 (42%), Gaps = 27/163 (16%)

Query: 28  RAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQHS 87
           R E   +   +  + ++E + + E +L+++E ++  L  E N L+ +L+   E +     
Sbjct: 849 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY----- 903

Query: 88  EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQ-AI 146
                 +  E+   +  A K +L++ + E+E                LE+ E R  Q   
Sbjct: 904 ------AEAEEMRVRLAAKKQELEEILHEMEAR--------------LEEEEDRGQQLQA 943

Query: 147 ERNAFLESELDEKENL-LESVQRLKDEARDLRQELAVQQKQEK 188
           ER    +  LD +E L  E   R K +   +  E  +++ +++
Sbjct: 944 ERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 986



 Score = 28.9 bits (63), Expect = 6.8
 Identities = 16/72 (22%), Positives = 32/72 (44%)

Query: 1    MEDSGKTFSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETR 60
            +ED  K     +E+A          K++ E  +EE +      R+ + EL+   +  E  
Sbjct: 1858 VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAM 1917

Query: 61   NRDLLSENNRLR 72
             R++ +  ++LR
Sbjct: 1918 GREVNALKSKLR 1929



 Score = 28.5 bits (62), Expect = 8.8
 Identities = 24/107 (22%), Positives = 51/107 (47%), Gaps = 11/107 (10%)

Query: 27   QRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQH 86
            Q  E  ++E RE Q  ++         L+Q + + +++L +    R   E  KE+ E  +
Sbjct: 1825 QLEEQVEQEAREKQAATKS--------LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1876

Query: 87   S---EGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRA 130
            +   +  RQ+   E++  +  A + +LQ+ + E  ++N+ + R   A
Sbjct: 1877 ARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNA 1923


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 49/187 (26%), Positives = 88/187 (47%), Gaps = 21/187 (11%)

Query: 26   KQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRLRMELETIKEKFEVQ 85
            K+R    Q+  R+ +E + ++EA   T    +  ++ D ++E       L+ +K+K E +
Sbjct: 1169 KKREAEFQKMRRDLEEATLQHEATAAT----LRKKHADSVAELGEQIDNLQRVKQKLEKE 1224

Query: 86   HSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDFEQRL-NQ 144
             SE   +I  L  ++      K  L+K  R LE   D L   K     + E+ +QRL N 
Sbjct: 1225 KSEMKMEIDDLASNMETVSKAKGNLEKMCRALE---DQLSEIK-----TKEEEQQRLIND 1276

Query: 145  AIERNAFLESE-------LDEKENLLESVQRLKDEARDLRQELAVQQKQE-KPRTPMPSS 196
               + A L++E       LDEK+ L+  + R K       +EL  Q ++E K ++ +  +
Sbjct: 1277 LTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHA 1336

Query: 197  VEAERTD 203
            +++ R D
Sbjct: 1337 LQSSRHD 1343



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 56/242 (23%), Positives = 108/242 (44%), Gaps = 47/242 (19%)

Query: 10   SEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENN 69
            +EE++ N      +  +Q+ ++         EGS E E ++   L++ + +    L    
Sbjct: 1016 AEEDKVNTLTKAKIKLEQQVDDL--------EGSLEQEKKIRMDLERAKRKLEGDLKLAQ 1067

Query: 70   RLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDL----- 124
               M++E  K++ + +  +   ++S L+  +   +A+  QLQK I+EL+   ++L     
Sbjct: 1068 ESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIE 1127

Query: 125  -ERAKRATI--------MSLEDFEQRLNQA-------IERNAFLESELDE-KENLLESVQ 167
             ERA RA            LE+  +RL +A       IE N   E+E  + + +L E+  
Sbjct: 1128 AERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATL 1187

Query: 168  RLKDEARDLRQELA---------------VQQKQEKPRTPMPSSVE--AERTDTAVQATG 210
            + +  A  LR++ A               V+QK EK ++ M   ++  A   +T  +A G
Sbjct: 1188 QHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKG 1247

Query: 211  SV 212
            ++
Sbjct: 1248 NL 1249



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 56/200 (28%), Positives = 90/200 (45%), Gaps = 46/200 (23%)

Query: 11   EEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAEL-------ETQLQQIETRNRD 63
            ++++ N+ K LA  +KQ+ E T  EL   Q+ SR    EL       E  L Q+ET  R 
Sbjct: 1447 DKKQRNFDKILA-EWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKR- 1504

Query: 64   LLSENNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDD 123
               EN  L+ E+  + E    Q +EG ++I  LE              K  +++EQ   +
Sbjct: 1505 ---ENKNLQQEISDLTE----QIAEGGKRIHELE--------------KIKKQVEQEKSE 1543

Query: 124  LERAKRATIMSLEDFEQR-------LNQA---IERN-AFLESELDEKE----NLLESVQR 168
            L+ A      SLE  E +       LNQ    ++R  A  + E+D+ +     ++ES+Q 
Sbjct: 1544 LQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQS 1603

Query: 169  LKD-EARDLRQELAVQQKQE 187
              D E R     + +++K E
Sbjct: 1604 TLDAEIRSRNDAIRLKKKME 1623



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 32/118 (27%), Positives = 63/118 (53%), Gaps = 22/118 (18%)

Query: 74  ELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIM 133
           E+  +KE+FE             +++LA+T+A + +L++ +  L Q  +DL+   +A   
Sbjct: 852 EMANMKEEFE-----------KTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEAD 900

Query: 134 SLEDFEQRLNQAIERNAFLESEL--------DEKE---NLLESVQRLKDEARDLRQEL 180
           SL D E+R +Q I+    LE+++        DE+E    L    ++L+DE  +L++++
Sbjct: 901 SLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDI 958



 Score = 37.0 bits (84), Expect = 0.025
 Identities = 33/158 (20%), Positives = 71/158 (44%), Gaps = 22/158 (13%)

Query: 25   YKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSENNRL---RMELETIKEK 81
            Y ++ +     + +   G + +  ++E   +Q+E   +   +  + L   R + + ++E+
Sbjct: 1291 YSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQ 1350

Query: 82   FEVQH---SEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERAKRATIMSLEDF 138
            +E +    +E  R +S    ++AQ +       KY  +  Q  ++LE AK+     L+D 
Sbjct: 1351 YEEEQEAKAELQRAMSKANSEVAQWRT------KYETDAIQRTEELEEAKKKLAQRLQDA 1404

Query: 139  EQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDL 176
            E+ +     + A LE          ++ QRL++E  DL
Sbjct: 1405 EEHVEAVNAKCASLE----------KTKQRLQNEVEDL 1432



 Score = 32.0 bits (71), Expect = 0.80
 Identities = 46/215 (21%), Positives = 87/215 (40%), Gaps = 40/215 (18%)

Query: 11   EEEEANYWKDLAMTYKQRAENTQ---EELREFQEGSREYEAELETQLQQIE----TRNRD 63
            EE EA+   +     + + E  Q   E  R+  E   E +      ++ +E    T + +
Sbjct: 1549 EEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAE 1608

Query: 64   LLSENN--RLRMELETIKEKFEVQHS----------EGYRQISA--------LEDDLAQT 103
            + S N+  RL+ ++E    + E+Q +            YR   A        L+D L   
Sbjct: 1609 IRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQ 1668

Query: 104  KAIKDQ----------LQKYIRELEQANDDLERAKRATIMSLEDFEQRLNQAIERNAFLE 153
            + +K+Q          LQ  I EL    +  ER+++     L D  +R+     +N  L 
Sbjct: 1669 EDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSL- 1727

Query: 154  SELDEKENLLESVQRLKDEARDLRQELAVQQKQEK 188
              ++ K+ L   + +++ E  D+ QE    +++ K
Sbjct: 1728 --INTKKKLETDISQIQGEMEDIIQEARNAEEKAK 1760


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.124    0.334 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,627,515
Number of Sequences: 37866
Number of extensions: 624546
Number of successful extensions: 8636
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 358
Number of HSP's successfully gapped in prelim test: 887
Number of HSP's that attempted gapping in prelim test: 4213
Number of HSP's gapped (non-prelim): 3822
length of query: 335
length of database: 18,247,518
effective HSP length: 103
effective length of query: 232
effective length of database: 14,347,320
effective search space: 3328578240
effective search space used: 3328578240
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press