Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 221316616
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221316616 extracellular matrix protein 1 isoform 2 precursor
[Homo sapiens]
(415 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221316616 extracellular matrix protein 1 isoform 2 precursor ... 895 0.0
gi|221316614 extracellular matrix protein 1 isoform 1 precursor ... 545 e-155
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 46 5e-05
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 46 5e-05
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 46 7e-05
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 46 7e-05
gi|149999615 variable charge, X-linked 3B [Homo sapiens] 45 1e-04
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 44 3e-04
gi|7019535 B-cell linker isoform 1 [Homo sapiens] 44 4e-04
gi|209180481 Cas-Br-M (murine) ecotropic retroviral transforming... 44 4e-04
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 43 5e-04
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 43 6e-04
gi|66932943 variable charge, X chromosome [Homo sapiens] 43 6e-04
gi|206597502 NESH protein isoform 2 [Homo sapiens] 42 0.001
gi|7705981 NESH protein isoform 1 [Homo sapiens] 42 0.001
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 42 0.001
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 41 0.002
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 41 0.002
gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [H... 41 0.002
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 41 0.002
gi|48762947 variable charge, X-linked 3A [Homo sapiens] 40 0.003
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 40 0.003
gi|166235901 B-cell linker isoform 2 [Homo sapiens] 40 0.003
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 40 0.004
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 40 0.004
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 39 0.007
gi|38787970 tensin like C1 domain containing phosphatase isoform... 39 0.007
gi|38787957 tensin like C1 domain containing phosphatase isoform... 39 0.007
gi|38787941 tensin like C1 domain containing phosphatase isoform... 39 0.007
gi|19924099 synapsin I isoform Ia [Homo sapiens] 39 0.007
>gi|221316616 extracellular matrix protein 1 isoform 2 precursor
[Homo sapiens]
Length = 415
Score = 895 bits (2312), Expect = 0.0
Identities = 415/415 (100%), Positives = 415/415 (100%)
Query: 1 MGTTARAALVLTYLAVASAASEGGFTATGQRQLRPEHFQEVGYAAPPSPPLSRSLPMDHP 60
MGTTARAALVLTYLAVASAASEGGFTATGQRQLRPEHFQEVGYAAPPSPPLSRSLPMDHP
Sbjct: 1 MGTTARAALVLTYLAVASAASEGGFTATGQRQLRPEHFQEVGYAAPPSPPLSRSLPMDHP 60
Query: 61 DSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELPSL 120
DSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELPSL
Sbjct: 61 DSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELPSL 120
Query: 121 QHPNEQKEGTPAPFGDQSHPEPESWNAAQHCQQDRSQGGWGHRLDGFPPGRPSPDNLNQI 180
QHPNEQKEGTPAPFGDQSHPEPESWNAAQHCQQDRSQGGWGHRLDGFPPGRPSPDNLNQI
Sbjct: 121 QHPNEQKEGTPAPFGDQSHPEPESWNAAQHCQQDRSQGGWGHRLDGFPPGRPSPDNLNQI 180
Query: 181 CLPNRQHVVYGPWNLPQSSYSHLTRQGETLNFLEIGYSRCCHCRSHTNRLECAKLVWEDT 240
CLPNRQHVVYGPWNLPQSSYSHLTRQGETLNFLEIGYSRCCHCRSHTNRLECAKLVWEDT
Sbjct: 181 CLPNRQHVVYGPWNLPQSSYSHLTRQGETLNFLEIGYSRCCHCRSHTNRLECAKLVWEDT 240
Query: 241 LDKYCDREYAVKTHHHLCCRHPPSPTRDECFARRAPYPNYDRDILTIDIGRVTPNLMGHL 300
LDKYCDREYAVKTHHHLCCRHPPSPTRDECFARRAPYPNYDRDILTIDIGRVTPNLMGHL
Sbjct: 241 LDKYCDREYAVKTHHHLCCRHPPSPTRDECFARRAPYPNYDRDILTIDIGRVTPNLMGHL 300
Query: 301 CGNQRVLTKHKHIPGLIHNMTARCCDLPFPEQACCAEEEKLTFINDLCGPRRNIWRDPAL 360
CGNQRVLTKHKHIPGLIHNMTARCCDLPFPEQACCAEEEKLTFINDLCGPRRNIWRDPAL
Sbjct: 301 CGNQRVLTKHKHIPGLIHNMTARCCDLPFPEQACCAEEEKLTFINDLCGPRRNIWRDPAL 360
Query: 361 CCYLSPGDEQVNCFNINYLRNVALVSGDTENAKGQGEQGSTGGTNISSTSEPKEE 415
CCYLSPGDEQVNCFNINYLRNVALVSGDTENAKGQGEQGSTGGTNISSTSEPKEE
Sbjct: 361 CCYLSPGDEQVNCFNINYLRNVALVSGDTENAKGQGEQGSTGGTNISSTSEPKEE 415
>gi|221316614 extracellular matrix protein 1 isoform 1 precursor
[Homo sapiens]
Length = 540
Score = 545 bits (1403), Expect = e-155
Identities = 273/397 (68%), Positives = 296/397 (74%), Gaps = 24/397 (6%)
Query: 1 MGTTARAALVLTYLAVASAASEGGFTATGQRQLRPEHFQEVGYAAPPSPPLSRSLPMDHP 60
MGTTARAALVLTYLAVASAASEGGFTATGQRQLRPEHFQEVGYAAPPSPPLSRSLPMDHP
Sbjct: 1 MGTTARAALVLTYLAVASAASEGGFTATGQRQLRPEHFQEVGYAAPPSPPLSRSLPMDHP 60
Query: 61 DSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELPSL 120
DSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELPSL
Sbjct: 61 DSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELPSL 120
Query: 121 QHPNEQKEGTPAPFGDQSHPEPESWNAAQHCQQDRSQGGWGHRLDGFPPGRPSPDNLNQI 180
QHPNEQKEGTPAPFGDQSHPEPESWNAAQHCQQDRSQGGWGHRLDGFPPGRPSPDNLNQI
Sbjct: 121 QHPNEQKEGTPAPFGDQSHPEPESWNAAQHCQQDRSQGGWGHRLDGFPPGRPSPDNLNQI 180
Query: 181 CLPNRQHVVYGPWNLPQSSYSHLTRQGETLNFLEIGYSRCCHCRSHTNRLECAKLVWEDT 240
CLPNRQHVVYGPWNLPQSSYSHLTRQGETLNFLEIGYSRCCHCRSHTNRLECAKLVWE+
Sbjct: 181 CLPNRQHVVYGPWNLPQSSYSHLTRQGETLNFLEIGYSRCCHCRSHTNRLECAKLVWEEA 240
Query: 241 LDKYCDREYAVKTHHHLCCRHPPSPTRDECFARRAPYPNY--------DRDI-----LTI 287
+ ++C+ E++VKT H CC R CF AP P+Y DI L
Sbjct: 241 MSRFCEAEFSVKTRPHWCCTR-QGEARFSCFQEEAPQPHYQLRACPSHQPDISSGLELPF 299
Query: 288 DIGRVTPNLMGHLCGNQRVLTKHKHIPGL--IHNMTARCCDLPFPEQACCAEEEKLT--- 342
G T + + ++C +R + +++P + L Q CC + T
Sbjct: 300 PPGVPTLDNIKNICHLRRFRSVPRNLPATDPLQRELLALIQLEREFQRCCRQGNNHTCTW 359
Query: 343 -----FINDLCGPRRNIWRDPALCCYLSPGDEQVNCF 374
++ C + LCC P + CF
Sbjct: 360 KAWEDTLDKYCDREYAVKTHHHLCCRHPPSPTRDECF 396
Score = 421 bits (1083), Expect = e-118
Identities = 204/249 (81%), Positives = 209/249 (83%), Gaps = 7/249 (2%)
Query: 167 FPPGRPSPDNLNQICLPNRQHVVYGPWNLPQSSYSHLTRQGETLNFLEIGYSRCCHCRSH 226
FPPG P+ DN+ IC R V P NLP + L R+ L LE + RCC
Sbjct: 299 FPPGVPTLDNIKNICHLRRFRSV--PRNLPATD--PLQRELLALIQLEREFQRCCR---Q 351
Query: 227 TNRLECAKLVWEDTLDKYCDREYAVKTHHHLCCRHPPSPTRDECFARRAPYPNYDRDILT 286
N C WEDTLDKYCDREYAVKTHHHLCCRHPPSPTRDECFARRAPYPNYDRDILT
Sbjct: 352 GNNHTCTWKAWEDTLDKYCDREYAVKTHHHLCCRHPPSPTRDECFARRAPYPNYDRDILT 411
Query: 287 IDIGRVTPNLMGHLCGNQRVLTKHKHIPGLIHNMTARCCDLPFPEQACCAEEEKLTFIND 346
IDIGRVTPNLMGHLCGNQRVLTKHKHIPGLIHNMTARCCDLPFPEQACCAEEEKLTFIND
Sbjct: 412 IDIGRVTPNLMGHLCGNQRVLTKHKHIPGLIHNMTARCCDLPFPEQACCAEEEKLTFIND 471
Query: 347 LCGPRRNIWRDPALCCYLSPGDEQVNCFNINYLRNVALVSGDTENAKGQGEQGSTGGTNI 406
LCGPRRNIWRDPALCCYLSPGDEQVNCFNINYLRNVALVSGDTENAKGQGEQGSTGGTNI
Sbjct: 472 LCGPRRNIWRDPALCCYLSPGDEQVNCFNINYLRNVALVSGDTENAKGQGEQGSTGGTNI 531
Query: 407 SSTSEPKEE 415
SSTSEPKEE
Sbjct: 532 SSTSEPKEE 540
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 46.2 bits (108), Expect = 5e-05
Identities = 43/167 (25%), Positives = 63/167 (37%), Gaps = 27/167 (16%)
Query: 45 APPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGP 104
+P SPP S P++S+ PP E PP A+P ++ L+ LP E+
Sbjct: 669 SPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLM--SLPLEESPLL 726
Query: 105 PLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPESWNAAQHCQQDRSQGGWGHRL 164
PLP+E P L +E +P P P PE + + ++
Sbjct: 727 PLPEE--------PQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEE----------- 767
Query: 165 DGFPPGRPSPDNLNQICLPNRQHV---VYGPWNLPQSSYSHLTRQGE 208
P P P+ +P H+ GP PQ HL+ Q E
Sbjct: 768 ---PHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTE 811
Score = 45.1 bits (105), Expect = 1e-04
Identities = 33/102 (32%), Positives = 47/102 (46%), Gaps = 6/102 (5%)
Query: 45 APPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEAT--PLQQEKLLPAQLPAEKEV 102
+PPSP L L P++S PPFE +S + PPP + T P + +L P P E +
Sbjct: 526 SPPSPALETPLSPP-PEASPLSPPFE-ESPLSPPPEELPTSPPPEASRLSPP--PEESPM 581
Query: 103 GPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPES 144
PP + + E L P E+ +P P P PE+
Sbjct: 582 SPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEA 623
Score = 42.0 bits (97), Expect = 0.001
Identities = 33/103 (32%), Positives = 45/103 (43%), Gaps = 6/103 (5%)
Query: 47 PSPPLSRSLPMDHP-DSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQ-LPAEKEVGP 104
P+ PL +L + P + S PP E PP S +PL++ L P + P +
Sbjct: 475 PASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALET 534
Query: 105 PL--PQEAVPLQK--ELPSLQHPNEQKEGTPAPFGDQSHPEPE 143
PL P EA PL E L P E+ +P P + P PE
Sbjct: 535 PLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPE 577
Score = 40.8 bits (94), Expect = 0.002
Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 10/109 (9%)
Query: 45 APPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQE--ATPLQQEKLLP-------AQ 95
+P SPP S P++S+ PPFE +S + PPP + + P + +L P +
Sbjct: 579 SPMSPPPEESPMSPPPEASRLFPPFE-ESPLSPPPEESPLSPPPEASRLSPPPEDSPMSP 637
Query: 96 LPAEKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPES 144
P E + PP + + L P E+ +P P + P PE+
Sbjct: 638 PPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEA 686
Score = 40.4 bits (93), Expect = 0.003
Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 10/108 (9%)
Query: 45 APPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQE--ATPLQQEKLLPAQL------ 96
+P SPP S P++S+ PP E S + PPP + + P + +L P +
Sbjct: 606 SPLSPPPEESPLSPPPEASRLSPPPE-DSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSP 664
Query: 97 -PAEKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPE 143
P E + PP + E L P E +P P + P PE
Sbjct: 665 PPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPE 712
Score = 38.9 bits (89), Expect = 0.009
Identities = 27/100 (27%), Positives = 38/100 (38%), Gaps = 1/100 (1%)
Query: 44 AAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVG 103
A+P SPP S P+ PP E S++ PPP + E+ + P +
Sbjct: 542 ASPLSPPFEESPLSPPPEELPTSPPPEA-SRLSPPPEESPMSPPPEESPMSPPPEASRLF 600
Query: 104 PPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPE 143
PP + + E L P E +P P P PE
Sbjct: 601 PPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPE 640
Score = 36.6 bits (83), Expect = 0.043
Identities = 48/155 (30%), Positives = 60/155 (38%), Gaps = 34/155 (21%)
Query: 39 QEVGYAAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPA 98
QE+G P P P P + GP G PPPS QE P+QLP+
Sbjct: 4275 QELGAGPRPQGPPRLPAP---PGALSTGPVL-GPVHPTPPPSSP-----QEPKRPSQLPS 4325
Query: 99 EKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEP--ESWNAAQHCQQDRS 156
P +P + +LP HP GTP P G P P S AAQ S
Sbjct: 4326 --------PSSQLPTEAQLPPT-HP-----GTPKPQGPTLEPPPGRVSPAAAQLADTLFS 4371
Query: 157 QGGWGHRLDGFPPGRPSPDNLNQICLPNRQHVVYG 191
+G L + P PDNL + P + +V G
Sbjct: 4372 KG-----LGPWDP----PDNLAETQKPEQSSLVPG 4397
Score = 35.8 bits (81), Expect = 0.073
Identities = 35/121 (28%), Positives = 49/121 (40%), Gaps = 11/121 (9%)
Query: 27 ATGQRQLRPEHFQEVGYAAPPSPPLSRSLPMDHPDS---SQHGPPFEGQSQVQPPPSQEA 83
A G + +R Q + SPP P D PD+ + G P G P +E
Sbjct: 352 AQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQP--KEP 409
Query: 84 TPLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPE 143
PLQ E + + E PQ PL +E+P L P E+ +P P + P PE
Sbjct: 410 GPLQCEAKPLGKAGVQLE-----PQLEAPLNEEMPLLP-PPEESPLSPPPEESPTSPPPE 463
Query: 144 S 144
+
Sbjct: 464 A 464
Score = 35.4 bits (80), Expect = 0.096
Identities = 32/111 (28%), Positives = 43/111 (38%), Gaps = 5/111 (4%)
Query: 32 QLRPEHFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKL 91
QL P+ + P PP S P+ S PP E PP A+PL +
Sbjct: 425 QLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPE--A 482
Query: 92 LPAQLPAEKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEP 142
L P E+ P P+E+ PL P P E +P ++S P P
Sbjct: 483 LHLSRPLEESPLSPPPEES-PLSP--PPESSPFSPLEESPLSPPEESPPSP 530
Score = 33.1 bits (74), Expect = 0.48
Identities = 29/110 (26%), Positives = 40/110 (36%), Gaps = 6/110 (5%)
Query: 39 QEVGYAAPP-----SPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLP 93
+E+ + PP SPP S P+ S PP E P +P +E L
Sbjct: 559 EELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLS 618
Query: 94 AQLPAEKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPE 143
A + PP P +E P + P E +P P + P PE
Sbjct: 619 PPPEASRLSPPPEDSPMSPPPEESP-MSPPPEVSRLSPLPVVSRLSPPPE 667
Score = 32.7 bits (73), Expect = 0.62
Identities = 28/105 (26%), Positives = 38/105 (36%), Gaps = 5/105 (4%)
Query: 45 APPSPPLSRSLPMDHPDSSQHGP----PFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEK 100
+P SPP S P+SS P P + P P+ E + P P E+
Sbjct: 492 SPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEE 551
Query: 101 EVGPPLPQE-AVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPES 144
P P+E E L P E+ +P P P PE+
Sbjct: 552 SPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEA 596
Score = 31.2 bits (69), Expect = 1.8
Identities = 47/179 (26%), Positives = 61/179 (34%), Gaps = 29/179 (16%)
Query: 46 PPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGP- 104
P P LP+ P P G+ + P +PL +E LP E + P
Sbjct: 871 PGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEE--LPLSPSGEPSLSPQ 928
Query: 105 -----PLPQEAVP-LQKELPSLQHPNEQKEGTPAPFGDQSHPEPESWNAAQHCQQDRSQG 158
PLP P + P P + E PFG + +PES AA + S
Sbjct: 929 LMPPDPLPPPLSPIITAAAPPALSPLGELE---YPFGAKGDSDPESPLAAPILETPISPP 985
Query: 159 GWGHRLD-------------GFPPGRPSP---DNLNQICLPNRQHVVYGPWNLPQSSYS 201
+ D G P G SP + L C P QH + P N P S S
Sbjct: 986 PEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLV-PQNSPPSQCS 1043
Score = 29.6 bits (65), Expect = 5.3
Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 4/79 (5%)
Query: 68 PFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGPPLPQE--AVPLQKELPSLQHPNE 125
P + + PPP + E+ + P + PP P+E A PL + L L P E
Sbjct: 433 PLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPP-PEELPASPLPEAL-HLSRPLE 490
Query: 126 QKEGTPAPFGDQSHPEPES 144
+ +P P P PES
Sbjct: 491 ESPLSPPPEESPLSPPPES 509
Score = 29.6 bits (65), Expect = 5.3
Identities = 23/81 (28%), Positives = 32/81 (39%), Gaps = 5/81 (6%)
Query: 66 GPPFEGQSQVQPPPSQEATPLQQE--KLLPAQLPAEKEVGPPLPQEAVPLQKELPSLQHP 123
G PF GQ PP P+ ++ +L P L G P + + P EL + HP
Sbjct: 2892 GTPFPGQG---PPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHP 2948
Query: 124 NEQKEGTPAPFGDQSHPEPES 144
+G P G + P S
Sbjct: 2949 TPHTKGPTLPTGLELVNRPPS 2969
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 46.2 bits (108), Expect = 5e-05
Identities = 46/156 (29%), Positives = 60/156 (38%), Gaps = 19/156 (12%)
Query: 34 RPEHFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQ----PPPSQEATPLQQE 89
RP+ G P P +S P GPP +G +Q Q PP + P Q
Sbjct: 128 RPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 187
Query: 90 KLLPAQLPAEKEVGPPLPQ-------EAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEP 142
K P K GPP PQ ++ P + + P Q N Q +G P P G P P
Sbjct: 188 KKPQGPPPPGKPQGPP-PQGDKSRSSQSPPGKPQGPPPQGGN-QPQGPPPPPGKPQGPPP 245
Query: 143 ESWNAAQ------HCQQDRSQGGWGHRLDGFPPGRP 172
+ N Q Q +QGG + PPG+P
Sbjct: 246 QGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKP 281
Score = 37.4 bits (85), Expect = 0.025
Identities = 47/143 (32%), Positives = 57/143 (39%), Gaps = 20/143 (13%)
Query: 46 PPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQ---PPPSQEATPLQQEKLLP-AQLPAEKE 101
PP SRS P P Q GPP +G +Q Q PPP + P Q P P K
Sbjct: 81 PPQGDKSRS-PRSPPGKPQ-GPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKP 138
Query: 102 VGPPLPQ-------EAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPESWNAAQ-HCQQ 153
GPP PQ + P + + P Q N Q +G P P G P P+ Q
Sbjct: 139 QGPP-PQGDKSRSPRSPPGKPQGPPPQGGN-QPQGPPPPPGKPQGPPPQGGKKPQGPPPP 196
Query: 154 DRSQG----GWGHRLDGFPPGRP 172
+ QG G R PPG+P
Sbjct: 197 GKPQGPPPQGDKSRSSQSPPGKP 219
Score = 37.4 bits (85), Expect = 0.025
Identities = 30/94 (31%), Positives = 39/94 (41%), Gaps = 12/94 (12%)
Query: 46 PPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPA--QLPAEKE-- 101
PP PP P + GPP G+ Q PP+Q + Q + P Q P ++E
Sbjct: 233 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQ--GPPAQGGSKSQSARSPPGKPQGPPQQEGN 290
Query: 102 --VGPPLPQEAVPLQKELPSLQHPNEQKEGTPAP 133
GPP P P Q + P P Q +G P P
Sbjct: 291 NPQGPPPPAGGNPQQPQAP----PAGQPQGPPRP 320
Score = 37.0 bits (84), Expect = 0.033
Identities = 38/132 (28%), Positives = 46/132 (34%), Gaps = 28/132 (21%)
Query: 46 PPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGPP 105
PP PP P + GPP G+ Q PP Q +K + P K GPP
Sbjct: 50 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP--------QGDKSRSPRSPPGKPQGPP 101
Query: 106 LPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPESWNAAQ-HCQQDRSQG----GW 160
PQ Q +G P P G P P+ N Q + QG G
Sbjct: 102 -PQ--------------GGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGD 146
Query: 161 GHRLDGFPPGRP 172
R PPG+P
Sbjct: 147 KSRSPRSPPGKP 158
Score = 33.1 bits (74), Expect = 0.48
Identities = 22/65 (33%), Positives = 27/65 (41%), Gaps = 6/65 (9%)
Query: 46 PPSPPLSRSLPMDHPDSSQHGPP-FEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGP 104
PP+ S+S P GPP EG + PPP P Q P PA + GP
Sbjct: 263 PPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ-----PQAPPAGQPQGP 317
Query: 105 PLPQE 109
P P +
Sbjct: 318 PRPPQ 322
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 45.8 bits (107), Expect = 7e-05
Identities = 38/143 (26%), Positives = 52/143 (36%), Gaps = 15/143 (10%)
Query: 35 PEHFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPPFE---GQSQVQPPPSQEATPLQQEKL 91
P+ + + PP P RS P+ P S + PP G+S PPP + +
Sbjct: 335 PQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRA 394
Query: 92 LPA--QLPAEKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPESWNAAQ 149
LPA QLP+ V P PL + PS P T G Q P + W +
Sbjct: 395 LPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRF 454
Query: 150 HCQQDRSQGGWGHRLDGFPPGRP 172
+ H + PP P
Sbjct: 455 YF----------HPISDLPPPEP 467
Score = 30.4 bits (67), Expect = 3.1
Identities = 25/97 (25%), Positives = 34/97 (35%), Gaps = 9/97 (9%)
Query: 46 PPSPPLSRSLPMDHPDSSQHGPPFEGQSQV----QPPPSQEATPLQQEKLLPAQLP---- 97
PP PP + P H ++ PP + V +P S +A P P P
Sbjct: 265 PPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPS 324
Query: 98 -AEKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAP 133
+ + P LPQ + L P L P P P
Sbjct: 325 SSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPP 361
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 45.8 bits (107), Expect = 7e-05
Identities = 38/143 (26%), Positives = 52/143 (36%), Gaps = 15/143 (10%)
Query: 35 PEHFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPPFE---GQSQVQPPPSQEATPLQQEKL 91
P+ + + PP P RS P+ P S + PP G+S PPP + +
Sbjct: 335 PQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRA 394
Query: 92 LPA--QLPAEKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPESWNAAQ 149
LPA QLP+ V P PL + PS P T G Q P + W +
Sbjct: 395 LPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRF 454
Query: 150 HCQQDRSQGGWGHRLDGFPPGRP 172
+ H + PP P
Sbjct: 455 YF----------HPISDLPPPEP 467
Score = 30.4 bits (67), Expect = 3.1
Identities = 25/97 (25%), Positives = 34/97 (35%), Gaps = 9/97 (9%)
Query: 46 PPSPPLSRSLPMDHPDSSQHGPPFEGQSQV----QPPPSQEATPLQQEKLLPAQLP---- 97
PP PP + P H ++ PP + V +P S +A P P P
Sbjct: 265 PPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPS 324
Query: 98 -AEKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAP 133
+ + P LPQ + L P L P P P
Sbjct: 325 SSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPP 361
>gi|149999615 variable charge, X-linked 3B [Homo sapiens]
Length = 216
Score = 45.1 bits (105), Expect = 1e-04
Identities = 45/145 (31%), Positives = 62/145 (42%), Gaps = 22/145 (15%)
Query: 15 AVASAASEGGFTATG----------QRQLRPEHFQEVGYAAPPSPPLSRSLPMDHPDS-- 62
AV + +E G A G Q +L PE G PLS+ ++ P S
Sbjct: 61 AVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVSEG---TQHDPLSQESELEEPLSQE 117
Query: 63 SQHGPPFEGQSQVQPPPSQEAT---PLQQEKLLPAQLPAEKEVGPPLPQEA---VPLQKE 116
S+ P +SQV+ P SQE+ PL QE + L E EV PL QE+ PL +E
Sbjct: 118 SEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQE 177
Query: 117 LPSLQHPNEQKEGTPAPFGDQSHPE 141
++ P Q+ P +S E
Sbjct: 178 -SEMEEPLSQESQVEEPLSQESEME 201
Score = 39.3 bits (90), Expect = 0.007
Identities = 29/76 (38%), Positives = 41/76 (53%), Gaps = 7/76 (9%)
Query: 50 PLSRSLPMDHPDS--SQHGPPFEGQSQVQPPPSQEAT---PLQQEKLLPAQLPAEKEVGP 104
PLS+ ++ P S S+ P +SQV+ P SQE+ PL QE + L E E+
Sbjct: 143 PLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQESQVEEPLSQESEMEE 202
Query: 105 PLPQEAVPLQKELPSL 120
PL QE+ +ELPS+
Sbjct: 203 PLSQESE--MEELPSV 216
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 43.9 bits (102), Expect = 3e-04
Identities = 48/191 (25%), Positives = 72/191 (37%), Gaps = 37/191 (19%)
Query: 31 RQLRPEHFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATP--LQQ 88
+Q+ P+ Q V A PP PP + P P Q PP + QSQ Q Q+ + Q
Sbjct: 984 QQMPPQLMQHV--APPPQPPQQQPQPQ-LPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQ 1040
Query: 89 EKLLPAQLPAEKEVGPP----------LPQE---AVPLQKEL--PSLQHPNEQKEGTPAP 133
+ +LP + V PP +P + +VP+ L P+ P+ K+ P P
Sbjct: 1041 QDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMP 1100
Query: 134 FG------------DQSHPEPESWNAAQHCQQDRSQGGWGHRLDGFPPGRPSPDNLNQIC 181
+S P S A+ + G + G P PS +
Sbjct: 1101 VNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPS-----HVV 1155
Query: 182 LPNRQHVVYGP 192
LP Q ++ GP
Sbjct: 1156 LPQNQLMMTGP 1166
Score = 32.3 bits (72), Expect = 0.81
Identities = 26/110 (23%), Positives = 43/110 (39%), Gaps = 16/110 (14%)
Query: 30 QRQLRPEHFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQE 89
Q+ L + G PPL ++ +S P F + PP + P++Q
Sbjct: 927 QQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLPEFSNR-----PPGYPSQPVEQR 981
Query: 90 KL--LPAQL---------PAEKEVGPPLPQEAVPLQKELPSLQHPNEQKE 128
L +P QL P +++ P LPQ+ P P Q +Q++
Sbjct: 982 PLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQ 1031
Score = 31.2 bits (69), Expect = 1.8
Identities = 29/107 (27%), Positives = 38/107 (35%), Gaps = 10/107 (9%)
Query: 49 PPLSRSLPMDHPDSSQHGPPF------EGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEV 102
P L+ P P S Q G P + Q Q+ P P Q PL Q P P
Sbjct: 421 PHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQN-NPLPQGFQQPVSSPGR--- 476
Query: 103 GPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPESWNAAQ 149
P + Q VP + Q PN+ + G P ++A Q
Sbjct: 477 NPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQ 523
>gi|7019535 B-cell linker isoform 1 [Homo sapiens]
Length = 456
Score = 43.5 bits (101), Expect = 4e-04
Identities = 41/159 (25%), Positives = 66/159 (41%), Gaps = 30/159 (18%)
Query: 30 QRQLRPEHFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQE 89
+++ RP H P+ P +R +D+ S +H PPF + PS+ + P ++
Sbjct: 102 EQETRPVH---------PALPFARGEYIDNRSSQRHSPPFS-----KTLPSKPSWPSEKA 147
Query: 90 KL---LPAQLPAEKEVGPPLPQ--------EAVPLQKELPSLQHPNEQKEGTP--APFGD 136
+L LPA +K PP P+ VP++ + HP E P AP +
Sbjct: 148 RLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKAPMVN 207
Query: 137 QS-HPEPESWNAAQHCQQDRSQGGWGHRLDGFPPGRPSP 174
+S P + + R+ G W + PP PSP
Sbjct: 208 RSTKPNSSTPASPPGTASGRNSGAWETKSP--PPAAPSP 244
>gi|209180481 Cas-Br-M (murine) ecotropic retroviral transforming
sequence-like 1 [Homo sapiens]
Length = 491
Score = 43.5 bits (101), Expect = 4e-04
Identities = 50/170 (29%), Positives = 60/170 (35%), Gaps = 36/170 (21%)
Query: 43 YAAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATP--LQQEKLLPAQLPA-- 98
YA PP PP S PM HP + G P SQ PPP A P + AQ+P
Sbjct: 341 YAPPPPPPPPISHPMPHPPQAA-GTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQMPPYM 399
Query: 99 -EKEVGPPLPQE-AVPLQKELPSLQHPNE-----QKEGT-PAPFGDQSHPEPESWNAAQH 150
GPP PQ P+ P +PN + +GT PF P W A
Sbjct: 400 NHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSPGIWPA--- 456
Query: 151 CQQDRSQGGWGHRLDGFPPGRPSPDNLNQICLPNRQHVVYGPWNLPQSSY 200
P G P P L P Q + GP + Q+ Y
Sbjct: 457 -----------------PRGPPPPPRLQG---PPSQTPLPGPHHPDQTRY 486
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 43.1 bits (100), Expect = 5e-04
Identities = 45/145 (31%), Positives = 56/145 (38%), Gaps = 20/145 (13%)
Query: 46 PPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQ---PPPSQEATPLQQEKLLP-AQLPAEKE 101
PP ++S P GPP +G +Q Q PPP + P Q P P K
Sbjct: 224 PPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 283
Query: 102 VGPPLPQ--------EAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPESWNAAQ---- 149
GPP PQ + P + + P Q N Q +G P P G P P+ N Q
Sbjct: 284 QGPP-PQGGSKSRSSRSPPGKPQGPPPQGGN-QPQGPPPPPGKPQGPPPQGGNKPQGPPP 341
Query: 150 --HCQQDRSQGGWGHRLDGFPPGRP 172
Q QGG R PPG+P
Sbjct: 342 PGKPQGPPPQGGSKSRSARSPPGKP 366
Score = 42.4 bits (98), Expect = 8e-04
Identities = 39/133 (29%), Positives = 45/133 (33%), Gaps = 28/133 (21%)
Query: 46 PPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGPP 105
PP PP P + GPP G+ Q PP K A+ P K GPP
Sbjct: 194 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG-------DNKSQSARSPPGKPQGPP 246
Query: 106 LPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPESWNAAQ------HCQQDRSQGG 159
PQ Q +G P P G P P+ N Q Q QGG
Sbjct: 247 -PQ--------------GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGG 291
Query: 160 WGHRLDGFPPGRP 172
R PPG+P
Sbjct: 292 SKSRSSRSPPGKP 304
Score = 40.8 bits (94), Expect = 0.002
Identities = 51/181 (28%), Positives = 67/181 (37%), Gaps = 20/181 (11%)
Query: 9 LVLTYLAVASAASEGGFTATGQRQLRPEHFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPP 68
L+L +A+ + +S ++ P APP P P Q GPP
Sbjct: 3 LILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQ-GPP 61
Query: 69 FEGQSQVQ---PPPSQEATPLQQEKLLP-AQLPAEKEVGPPLPQ-------EAVPLQKEL 117
+G +Q Q PPP + P Q P P K GPP PQ + P + +
Sbjct: 62 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP-PQGDKSRSPRSPPGKPQG 120
Query: 118 PSLQHPNEQKEGTPAPFGDQSHPEPESWNAAQ------HCQQDRSQGGWGHRLDGFPPGR 171
P Q N Q +G P P G P P+ N Q Q QG R PPG+
Sbjct: 121 PPPQGGN-QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGK 179
Query: 172 P 172
P
Sbjct: 180 P 180
Score = 38.9 bits (89), Expect = 0.009
Identities = 47/145 (32%), Positives = 57/145 (39%), Gaps = 22/145 (15%)
Query: 46 PPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQ---PPPSQEATPLQQEKLLP-AQLPAEKE 101
PP SRS P P Q GPP +G +Q Q PPP + P Q P P K
Sbjct: 102 PPQGDKSRS-PRSPPGKPQ-GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 159
Query: 102 VGPPLPQ--------EAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPESWNAAQ---- 149
GPP PQ + P + + P Q N Q +G P P G P P+ N Q
Sbjct: 160 QGPP-PQGDNKSRSSRSPPGKPQGPPPQGGN-QPQGPPPPPGKPQGPPPQGGNKPQGPPP 217
Query: 150 --HCQQDRSQGGWGHRLDGFPPGRP 172
Q QG + PPG+P
Sbjct: 218 PGKPQGPPPQGDNKSQSARSPPGKP 242
Score = 37.4 bits (85), Expect = 0.025
Identities = 28/92 (30%), Positives = 34/92 (36%), Gaps = 8/92 (8%)
Query: 46 PPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPP----SQEATPLQQEKLLPAQLPAEKE 101
PP PP P + GPP G+ Q PP S+ A + P Q
Sbjct: 318 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNP 377
Query: 102 VGPPLPQEAVPLQKELPSLQHPNEQKEGTPAP 133
GPP P P Q + P P Q +G P P
Sbjct: 378 QGPPPPAGGNPQQPQAP----PAGQPQGPPRP 405
Score = 34.3 bits (77), Expect = 0.21
Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 11/110 (10%)
Query: 46 PPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGPP 105
PP S+S P GPP +G +Q Q PP P P K GPP
Sbjct: 286 PPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG-----PPPQGGNKPQGPP 340
Query: 106 LP--QEAVPLQ--KELPSLQHPNEQKEGTPAPFGD--QSHPEPESWNAAQ 149
P + P Q + S + P + +G P G+ Q P P N Q
Sbjct: 341 PPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ 390
Score = 32.3 bits (72), Expect = 0.81
Identities = 22/65 (33%), Positives = 26/65 (40%), Gaps = 6/65 (9%)
Query: 46 PPSPPLSRSLPMDHPDSSQHGPP-FEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGP 104
PP S+S P GPP EG + PPP P Q P PA + GP
Sbjct: 348 PPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ-----PQAPPAGQPQGP 402
Query: 105 PLPQE 109
P P +
Sbjct: 403 PRPPQ 407
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 42.7 bits (99), Expect = 6e-04
Identities = 47/195 (24%), Positives = 77/195 (39%), Gaps = 26/195 (13%)
Query: 32 QLRPEHFQEVGYAAPPSPPLS--RSLPMDHPDSSQHGP-------PFEGQSQVQPPPSQE 82
+L P+H Q + + P S R+ P P S+ GP P S+ PPS +
Sbjct: 1024 ELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISE-GPVPSLPIRPSRAPSRTPGPPSAQ 1082
Query: 83 ATPLQQEKL--LPAQLPAE--KEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAP----F 134
++P+ + LP + PA+ + PP P+ P + P + P +PAP F
Sbjct: 1083 SSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEF 1142
Query: 135 GDQSHPEPESWNAAQHCQQDRSQGGWGHRLDGFPPGRPSPDNLNQICLPNRQHVVYGPWN 194
G P + Q G G G+ RP+ +P R V+ P +
Sbjct: 1143 GAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPT--------IPPRAGVISAPQS 1194
Query: 195 LPQSSYSHLTRQGET 209
++S LT + ++
Sbjct: 1195 HARASAGRLTPESQS 1209
>gi|66932943 variable charge, X chromosome [Homo sapiens]
Length = 206
Score = 42.7 bits (99), Expect = 6e-04
Identities = 39/120 (32%), Positives = 54/120 (45%), Gaps = 12/120 (10%)
Query: 30 QRQLRPEHFQEVGYAAPPSPPLSRSLPMDHPDS--SQHGPPFEGQSQVQPPPSQEAT--- 84
Q +L PE G PLS+ ++ P S S+ P +SQV+ P SQE+
Sbjct: 86 QHELPPEEPVSEG---TQHDPLSQEAELEEPLSQESEVEEPLSQESQVEEPLSQESEVEE 142
Query: 85 PLQQEKLLPAQLPAEKEVGPPLPQEA---VPLQKELPSLQHPNEQKEGTPAPFGDQSHPE 141
PL QE + L E EV PL QE+ PL +E ++ P Q+ P +S E
Sbjct: 143 PLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQE-SEMEEPLSQESQVEEPPSQESEME 201
Score = 33.1 bits (74), Expect = 0.48
Identities = 31/101 (30%), Positives = 41/101 (40%), Gaps = 11/101 (10%)
Query: 44 AAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVG 103
+AP +P P D P SQ P E + + PL QE L L E EV
Sbjct: 69 SAPAAPG-----PSDQP--SQELPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVE 121
Query: 104 PPLPQEA---VPLQKELPSLQHPNEQKEGTPAPFGDQSHPE 141
PL QE+ PL +E ++ P Q+ P +S E
Sbjct: 122 EPLSQESQVEEPLSQE-SEVEEPLSQESQVEEPLSQESEVE 161
>gi|206597502 NESH protein isoform 2 [Homo sapiens]
Length = 360
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/115 (29%), Positives = 46/115 (40%), Gaps = 33/115 (28%)
Query: 42 GYAAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKE 101
G AAPP+PPL SL PPP A + Q P +E
Sbjct: 222 GQAAPPAPPLPSSL--------------------DPPPPPAAVEVFQRP------PTLEE 255
Query: 102 VGPPLPQEAVPLQKELPSLQHPNEQKEGTPAP---FGDQSHPEPESWNAAQHCQQ 153
+ PP P E +PL +LP + + G P P FG P+ SW A + ++
Sbjct: 256 LSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFG----PDEPSWVPASYLEK 306
>gi|7705981 NESH protein isoform 1 [Homo sapiens]
Length = 366
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/115 (29%), Positives = 46/115 (40%), Gaps = 33/115 (28%)
Query: 42 GYAAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKE 101
G AAPP+PPL SL PPP A + Q P +E
Sbjct: 228 GQAAPPAPPLPSSL--------------------DPPPPPAAVEVFQRP------PTLEE 261
Query: 102 VGPPLPQEAVPLQKELPSLQHPNEQKEGTPAP---FGDQSHPEPESWNAAQHCQQ 153
+ PP P E +PL +LP + + G P P FG P+ SW A + ++
Sbjct: 262 LSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFG----PDEPSWVPASYLEK 312
>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
sapiens]
Length = 247
Score = 41.6 bits (96), Expect = 0.001
Identities = 49/180 (27%), Positives = 69/180 (38%), Gaps = 35/180 (19%)
Query: 9 LVLTYLAVASAAS--------EGGFTATGQRQLRPEHFQEVGYAAPPSPPLSRSLPMDHP 60
L + LA++SA S E F +G +PE + G P PP P
Sbjct: 6 LSVALLALSSAESSSEDVSQEESLFLISG----KPEGRRPQGGNQPQRPP--------PP 53
Query: 61 DSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELPSL 120
GPP +G +Q Q PP P + P Q + + PP P + E P
Sbjct: 54 PGKPQGPPPQGGNQSQGPPPPPGKPEGR----PPQGGNQSQGPPPHPG-----KPERPPP 104
Query: 121 QHPNEQKEGTPAPFGDQSHPEPESWNAAQH-----CQQDRSQGGWGHRLDGFPPGRPSPD 175
Q N Q +GTP P G P P+ N + + +R G++ G PP P+
Sbjct: 105 QGGN-QSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPE 163
Score = 36.2 bits (82), Expect = 0.056
Identities = 37/150 (24%), Positives = 52/150 (34%), Gaps = 9/150 (6%)
Query: 29 GQRQLRPEHFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPP----SQEAT 84
G+ Q P PP P P + SQ PP G+ + PP SQ
Sbjct: 55 GKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTP 114
Query: 85 PLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPES 144
P + P + PP P P + E P Q N Q +G P G P P+
Sbjct: 115 PPPGKPERPPPQGGNQSHRPPPP----PGKPERPPPQGGN-QSQGPPPHPGKPEGPPPQE 169
Query: 145 WNAAQHCQQDRSQGGWGHRLDGFPPGRPSP 174
N ++ + + + +G P P P
Sbjct: 170 GNKSRSARSPPGKPQGPPQQEGNKPQGPPP 199
Score = 36.2 bits (82), Expect = 0.056
Identities = 31/100 (31%), Positives = 37/100 (37%), Gaps = 8/100 (8%)
Query: 46 PPSPPLSRSLPMDHPDSSQHGPPFEGQSQ--VQPPPSQEATPLQQEKLLP-AQLPAEKEV 102
PP P HP + PP EG + PP + P QQE P P K
Sbjct: 145 PPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQ 204
Query: 103 GPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEP 142
GPP P P Q + P P + +G P P P P
Sbjct: 205 GPP-PAGGNPQQPQAP----PAGKPQGPPPPPQGGRPPRP 239
Score = 31.6 bits (70), Expect = 1.4
Identities = 32/127 (25%), Positives = 43/127 (33%), Gaps = 8/127 (6%)
Query: 21 SEGGFTATGQRQLRPEHFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPP-- 78
S+G G+ + RP PP P P + SQ PP G+ + PP
Sbjct: 68 SQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQG 127
Query: 79 --PSQEATPLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGD 136
S P + P + GPP P P E P Q N+ + P
Sbjct: 128 GNQSHRPPPPPGKPERPPPQGGNQSQGPP-PHPGKP---EGPPPQEGNKSRSARSPPGKP 183
Query: 137 QSHPEPE 143
Q P+ E
Sbjct: 184 QGPPQQE 190
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 41.2 bits (95), Expect = 0.002
Identities = 50/206 (24%), Positives = 83/206 (40%), Gaps = 32/206 (15%)
Query: 32 QLRPEHFQEVGYAAPPSPPLS--RSLPMDHPDSSQHGP-------PFEGQSQVQPPPSQE 82
+L P+H Q + + P S R+ P P S+ GP P S+ PPS +
Sbjct: 1063 ELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISE-GPVPSLPIRPSRAPSRTPGPPSAQ 1121
Query: 83 ATPLQQEKL--LPAQLPAE--KEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAP----F 134
++P+ + LP + PA+ + PP P+ P + P + P +PAP F
Sbjct: 1122 SSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEF 1181
Query: 135 GDQSHPEPESWNAAQHCQQDRSQGGWGHRLDGFPPGRPSPD-----------NLNQICLP 183
G P P A + + +S G R D +PSP + + +P
Sbjct: 1182 GGIGAP-PSPGVARREMEAPKSPG--TTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIP 1238
Query: 184 NRQHVVYGPWNLPQSSYSHLTRQGET 209
R V+ P + ++S LT + ++
Sbjct: 1239 PRAGVISAPQSHARASAGRLTPESQS 1264
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 41.2 bits (95), Expect = 0.002
Identities = 50/206 (24%), Positives = 83/206 (40%), Gaps = 32/206 (15%)
Query: 32 QLRPEHFQEVGYAAPPSPPLS--RSLPMDHPDSSQHGP-------PFEGQSQVQPPPSQE 82
+L P+H Q + + P S R+ P P S+ GP P S+ PPS +
Sbjct: 1063 ELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISE-GPVPSLPIRPSRAPSRTPGPPSAQ 1121
Query: 83 ATPLQQEKL--LPAQLPAE--KEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAP----F 134
++P+ + LP + PA+ + PP P+ P + P + P +PAP F
Sbjct: 1122 SSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEF 1181
Query: 135 GDQSHPEPESWNAAQHCQQDRSQGGWGHRLDGFPPGRPSPD-----------NLNQICLP 183
G P P A + + +S G R D +PSP + + +P
Sbjct: 1182 GGIGAP-PSPGVARREMEAPKSPG--TTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIP 1238
Query: 184 NRQHVVYGPWNLPQSSYSHLTRQGET 209
R V+ P + ++S LT + ++
Sbjct: 1239 PRAGVISAPQSHARASAGRLTPESQS 1264
>gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [Homo
sapiens]
Length = 1447
Score = 41.2 bits (95), Expect = 0.002
Identities = 28/114 (24%), Positives = 51/114 (44%), Gaps = 7/114 (6%)
Query: 61 DSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELPSL 120
+ Q+ PP +G+ P P TP ++ + ++ ++K+ GPP P+E +++ +
Sbjct: 1278 EDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNT 1337
Query: 121 QHPNEQKEGTPAPFGDQSHPEPESWNAAQHCQQDRSQGGWGHRLDGFPPGRPSP 174
+ ++ K+ + Q PES +A Q Q G G P PSP
Sbjct: 1338 EQKSKSKQHRVSRRAQQRAESPES--SAIESTQSTPQKGRGR-----PSKTPSP 1384
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 40.8 bits (94), Expect = 0.002
Identities = 43/160 (26%), Positives = 55/160 (34%), Gaps = 12/160 (7%)
Query: 21 SEGGFTATGQRQLRPEHFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPP- 79
S+G G+ + P PP P P + SQ PP G+ + PP
Sbjct: 152 SQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQG 211
Query: 80 ---SQEATPLQQEKLLPAQLPAEKEVGPP----LPQEAVPLQKELPSLQHPNEQKEGTPA 132
SQ P + P K GPP PQ P + P P + +G P
Sbjct: 212 GNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPP 271
Query: 133 PFGDQSHPEPESWNAAQHCQQDRSQGGWGHRLDGFPPGRP 172
P G+ P P Q QGG HR P G+P
Sbjct: 272 PGGNPQQPLPPPAGKPQG-PPPPPQGGRPHRP---PQGQP 307
Score = 40.4 bits (93), Expect = 0.003
Identities = 46/163 (28%), Positives = 56/163 (34%), Gaps = 22/163 (13%)
Query: 46 PPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGPP 105
PP P HP + GPP +G +Q Q PP + P P + GPP
Sbjct: 166 PPQGGNQSQGPPPHPGKPE-GPPPQGGNQSQGPPPRPGKPEG-----PPPQGGNQSQGPP 219
Query: 106 LPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPESWNAAQHCQQDRSQGGWGHRLD 165
P+ P E P Q N+ + P P G P P+ N Q
Sbjct: 220 -PRPGKP---EGPPSQGGNKPQGPPPHP-GKPQGPPPQEGNKPQRPPPP----------- 263
Query: 166 GFPPGRPSPDNLNQICLPNRQHVVYGPWNLPQSSYSHLTRQGE 208
G P G P P Q LP GP PQ H QG+
Sbjct: 264 GRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQ 306
Score = 38.1 bits (87), Expect = 0.015
Identities = 42/152 (27%), Positives = 54/152 (35%), Gaps = 13/152 (8%)
Query: 29 GQRQLRPEHFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPP----PSQEAT 84
G+ + RP PP P P + SQ PP G+ + QPP SQ
Sbjct: 55 GKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPP 114
Query: 85 PLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPES 144
P + P + GPP P+ P E P Q N Q +G P G P P+
Sbjct: 115 PRPGKPEGPPPQGGNQSQGPP-PRPGKP---EGPPPQGGN-QSQGPPPRPGKPEGPPPQG 169
Query: 145 WNAAQ----HCQQDRSQGGWGHRLDGFPPGRP 172
N +Q H + G PP RP
Sbjct: 170 GNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRP 201
Score = 34.7 bits (78), Expect = 0.16
Identities = 45/165 (27%), Positives = 61/165 (36%), Gaps = 20/165 (12%)
Query: 21 SEGGFTATGQRQLRPEHFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPP-- 78
S+G G+ + +P PP P P + SQ PP G+ + PP
Sbjct: 89 SQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQG 148
Query: 79 --PSQEATPLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGD 136
SQ P + P + GPP P P E P Q N Q +G P G
Sbjct: 149 GNQSQGPPPRPGKPEGPPPQGGNQSQGPP-PHPGKP---EGPPPQGGN-QSQGPPPRPGK 203
Query: 137 QSHPEPESWNAAQ-------HCQQDRSQGGWGHRLDGFP--PGRP 172
P P+ N +Q + SQG G++ G P PG+P
Sbjct: 204 PEGPPPQGGNQSQGPPPRPGKPEGPPSQG--GNKPQGPPPHPGKP 246
Score = 33.9 bits (76), Expect = 0.28
Identities = 36/133 (27%), Positives = 48/133 (36%), Gaps = 9/133 (6%)
Query: 21 SEGGFTATGQRQLRPEHFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPP-- 78
S+G G+ + P PP P P + SQ PP G+ + PP
Sbjct: 68 SQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQG 127
Query: 79 --PSQEATPLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGD 136
SQ P + P + GPP P+ P E P Q N Q +G P G
Sbjct: 128 GNQSQGPPPRPGKPEGPPPQGGNQSQGPP-PRPGKP---EGPPPQGGN-QSQGPPPHPGK 182
Query: 137 QSHPEPESWNAAQ 149
P P+ N +Q
Sbjct: 183 PEGPPPQGGNQSQ 195
Score = 31.6 bits (70), Expect = 1.4
Identities = 32/108 (29%), Positives = 42/108 (38%), Gaps = 9/108 (8%)
Query: 46 PPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPP--SQEATPLQQEKLLPAQLP--AEKE 101
PP P P + SQ PP G+ + PP +Q P + Q P +
Sbjct: 51 PPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQS 110
Query: 102 VGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPESWNAAQ 149
GPP P+ P E P Q N Q +G P G P P+ N +Q
Sbjct: 111 QGPP-PRPGKP---EGPPPQGGN-QSQGPPPRPGKPEGPPPQGGNQSQ 153
>gi|48762947 variable charge, X-linked 3A [Homo sapiens]
Length = 186
Score = 40.4 bits (93), Expect = 0.003
Identities = 41/128 (32%), Positives = 56/128 (43%), Gaps = 24/128 (18%)
Query: 15 AVASAASEGGFTATG----------QRQLRPEHFQEVGYAAPP-------SPPLSRSLPM 57
AV + +E G A G Q +L PE G P PLS+ +
Sbjct: 61 AVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESELEEPLSQESEV 120
Query: 58 DHPDS--SQHGPPFEGQSQVQPPPSQEAT---PLQQEKLLPAQLPAEKEVGPPLPQEAVP 112
+ P S SQ P +S+V+ P SQE+ PL QE + L E +V PL QE+
Sbjct: 121 EEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESE- 179
Query: 113 LQKELPSL 120
+ELPS+
Sbjct: 180 -MEELPSV 186
Score = 34.7 bits (78), Expect = 0.16
Identities = 37/107 (34%), Positives = 46/107 (42%), Gaps = 18/107 (16%)
Query: 40 EVGYAAP-PSPPLSRSLPMDHPDSSQHG-PPFEGQSQVQPPPSQEATPLQQEKLLPAQLP 97
E G AAP PS S+ LP QH PP E S+ + PL QE L L
Sbjct: 68 ESGPAAPGPSDQPSQELP-------QHELPPEEPVSE-----GTQHDPLSQESELEEPLS 115
Query: 98 AEKEVGPPLPQEA---VPLQKELPSLQHPNEQKEGTPAPFGDQSHPE 141
E EV PL QE+ PL +E ++ P Q+ P +S E
Sbjct: 116 QESEVEEPLSQESQVEEPLSQE-SEVEEPLSQESQVEEPLSQESEVE 161
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 40.4 bits (93), Expect = 0.003
Identities = 33/111 (29%), Positives = 42/111 (37%), Gaps = 19/111 (17%)
Query: 37 HFQEVGYAAPPSPPLSR--SLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPA 94
H + ++ PPSPP+ S P P S PP Q PPS A PLQ
Sbjct: 659 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS------QAPPSLAAPPLQ------- 705
Query: 95 QLPAEKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTP---APFGDQSHPEP 142
+P PP+ A P + P L P Q +P P + P P
Sbjct: 706 -VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPP 755
Score = 39.7 bits (91), Expect = 0.005
Identities = 32/106 (30%), Positives = 41/106 (38%), Gaps = 11/106 (10%)
Query: 44 AAPPS--PPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKE 101
A PPS PP + P+ P S PP S PP Q PL P Q+P
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPM---SPSATPPPQAPPPLAAP---PLQVPPSPP 742
Query: 102 VGPPLPQEAVPLQKELPSLQHPNEQKEGTP---APFGDQSHPEPES 144
PP+ A P + P L P Q +P P + P P++
Sbjct: 743 ASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA 788
Score = 38.5 bits (88), Expect = 0.011
Identities = 31/82 (37%), Positives = 36/82 (43%), Gaps = 14/82 (17%)
Query: 46 PPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQE----KLLPAQLPAEKE 101
PPSPPL+ LP+ P S PP +Q PS ATP Q P Q P +
Sbjct: 332 PPSPPLATPLPLAPPSPS--APP-----SLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQ 384
Query: 102 VGPPLPQEAVPLQKELPSLQHP 123
PP+ VP PSLQ P
Sbjct: 385 TIPPI---QVPHSLTSPSLQAP 403
Score = 37.0 bits (84), Expect = 0.033
Identities = 29/100 (29%), Positives = 36/100 (36%), Gaps = 4/100 (4%)
Query: 48 SPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGPPLP 107
+PP P+ P S PP E S + PP Q L L P + P P
Sbjct: 560 TPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPP 619
Query: 108 QEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPESWNA 147
Q P LP LQ P P + P P++ NA
Sbjct: 620 Q--APPXLALPPLQAP--PSPPASPPLSPLATPSPQAPNA 655
Score = 37.0 bits (84), Expect = 0.033
Identities = 32/104 (30%), Positives = 41/104 (39%), Gaps = 13/104 (12%)
Query: 45 APPSPPLSRSL-PMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVG 103
APPSPP S L P+ P S P +Q P S +P P Q P
Sbjct: 632 APPSPPASPPLSPLATP--SPQAPNALAVHLLQAPFSPPPSP-------PVQAPFSPPAS 682
Query: 104 PPLPQEAVPLQKELPSLQHPNEQKEGTP---APFGDQSHPEPES 144
PP+ A P + PSL P Q +P P + P P++
Sbjct: 683 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 726
Score = 34.7 bits (78), Expect = 0.16
Identities = 30/78 (38%), Positives = 35/78 (44%), Gaps = 14/78 (17%)
Query: 44 AAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVG 103
AAP PLS S P+ P P +++ PPP ATP LPA LP +
Sbjct: 292 AAPALGPLSSS-PLATPS------PSGTKARPVPPPDNAATP------LPATLPPSPPLA 338
Query: 104 PPLPQEAVPLQKELPSLQ 121
PLP A P PSLQ
Sbjct: 339 TPLPL-APPSPSAPPSLQ 355
Score = 33.9 bits (76), Expect = 0.28
Identities = 30/96 (31%), Positives = 34/96 (35%), Gaps = 22/96 (22%)
Query: 46 PPSPPLSRSL-----------------PMDHPDSSQHGPPFEGQSQVQP--PPSQEATPL 86
PPSPP S + P+ P S PP + P PP A PL
Sbjct: 707 PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL 766
Query: 87 QQEKLLPAQLPAEKEVGPP---LPQEAVPLQKELPS 119
Q PA LP PP P A P + LPS
Sbjct: 767 QVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPS 802
Score = 32.7 bits (73), Expect = 0.62
Identities = 33/109 (30%), Positives = 40/109 (36%), Gaps = 19/109 (17%)
Query: 42 GYAAPPSPPLSRSL-PMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEK 100
G P S LS S P+ P S GP G + PSQ Q P P K
Sbjct: 233 GLQRPASRSLSSSATPLSSPARS--GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 290
Query: 101 EVGPPL-PQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPESWNAA 148
+ P L P + PL TP+P G ++ P P NAA
Sbjct: 291 DAAPALGPLSSSPL---------------ATPSPSGTKARPVPPPDNAA 324
Score = 32.0 bits (71), Expect = 1.1
Identities = 44/173 (25%), Positives = 63/173 (36%), Gaps = 40/173 (23%)
Query: 45 APPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEA-----TPLQQEKLLPAQLPAE 99
APPS + P +S PP E + PPP Q A TP + PA P +
Sbjct: 519 APPS--------LQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQ 570
Query: 100 KEVGP---PLPQE----AVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPESWNAAQHCQ 152
P P P+ A P + P+L P Q +P P + P P+ A
Sbjct: 571 APPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP-PLSPLATPPPQ---APPXLA 626
Query: 153 QDRSQGGWGHRLDGFPPGRPSPDNLNQICLPNRQ-------HVVYGPWNLPQS 198
Q PP P+ L+ + P+ Q H++ P++ P S
Sbjct: 627 LPPLQA---------PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 670
Score = 32.0 bits (71), Expect = 1.1
Identities = 28/96 (29%), Positives = 37/96 (38%), Gaps = 8/96 (8%)
Query: 44 AAPPS--PPLSRSLPMDHPDSSQHGPPFEGQSQVQP--PPSQEATPLQQEKLLPAQLPAE 99
A PP PPL + P+ P S P ++ P PP+ PLQ PA P +
Sbjct: 751 ATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQ 810
Query: 100 KEVGP----PLPQEAVPLQKELPSLQHPNEQKEGTP 131
P P+ A P + P L P Q +P
Sbjct: 811 APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 846
Score = 30.4 bits (67), Expect = 3.1
Identities = 20/70 (28%), Positives = 28/70 (40%), Gaps = 3/70 (4%)
Query: 45 APPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGP 104
+P +PP ++LP PP +Q PPS + P Q +P L + P
Sbjct: 347 SPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQ---VPHSLTSPSLQAP 403
Query: 105 PLPQEAVPLQ 114
P P LQ
Sbjct: 404 PSPLALSSLQ 413
Score = 30.4 bits (67), Expect = 3.1
Identities = 28/111 (25%), Positives = 41/111 (36%), Gaps = 22/111 (19%)
Query: 46 PPSPPLSRSL------PMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAE 99
PPSPP S +L P PD+S GP PPP P++ P+
Sbjct: 843 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP------------PSRSPSS 890
Query: 100 KEVGPPLPQEAVPLQKELPSLQHPNEQKEG----TPAPFGDQSHPEPESWN 146
GP L + L+ + EG +P P + + P +W+
Sbjct: 891 TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS 941
Score = 29.6 bits (65), Expect = 5.3
Identities = 28/83 (33%), Positives = 33/83 (39%), Gaps = 10/83 (12%)
Query: 60 PDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELPS 119
P SS PP E QS + PP Q TP L L + PP PLQ
Sbjct: 503 PLSSLIMPPLETQSSLAPPSLQ--TP--PASLTTPPLENLPSLAPP------PLQTASAP 552
Query: 120 LQHPNEQKEGTPAPFGDQSHPEP 142
L P+ + PAP Q+ P P
Sbjct: 553 LTTPHLETPPCPAPCPLQAPPSP 575
>gi|166235901 B-cell linker isoform 2 [Homo sapiens]
Length = 433
Score = 40.4 bits (93), Expect = 0.003
Identities = 37/148 (25%), Positives = 62/148 (41%), Gaps = 31/148 (20%)
Query: 30 QRQLRPEHFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQE 89
+++ RP H P+ P +R +D+ S +H PPF + PS+ + P ++
Sbjct: 102 EQETRPVH---------PALPFARGEYIDNRSSQRHSPPFS-----KTLPSKPSWPSEKA 147
Query: 90 KL---LPAQLPAEKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPESWN 146
+L LPA +K PP P+ + + + N++ P + S P PE
Sbjct: 148 RLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPT---ESSSPPPE--- 201
Query: 147 AAQHCQQDRSQGGWGHRLDGFPPGRPSP 174
+ R+ G W + PP PSP
Sbjct: 202 ------KGRNSGAWETKSP--PPAAPSP 221
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 40.0 bits (92), Expect = 0.004
Identities = 33/131 (25%), Positives = 56/131 (42%), Gaps = 14/131 (10%)
Query: 32 QLRPEHFQEVGYAAPPSPPLS--RSLPMDHPDSSQHGP-------PFEGQSQVQPPPSQE 82
+L P+H Q + + P S R+ P P S+ GP P S+ PPS +
Sbjct: 1019 ELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISE-GPVPSLPIRPSRAPSRTPGPPSAQ 1077
Query: 83 ATPLQQEKL--LPAQLPAE--KEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQS 138
++P+ + LP + PA+ + PP P+ P + P + P P+P +
Sbjct: 1078 SSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLA 1137
Query: 139 HPEPESWNAAQ 149
P P ++ A+
Sbjct: 1138 GPGPAGYSTAR 1148
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 40.0 bits (92), Expect = 0.004
Identities = 29/102 (28%), Positives = 42/102 (41%), Gaps = 7/102 (6%)
Query: 42 GYAAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKE 101
G A PP+P + S P P SS PP PPP+ A P + + P ++
Sbjct: 183 GPAPPPAPSSASSSPSPSPSSSSPSPP-----PPPPPPAPPAPPAPRFDIYDPFHPTDEA 237
Query: 102 VGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPE 143
PP P P+ +P+ GTP+P ++ E E
Sbjct: 238 YSPP-PAPEQKYDPFEPTGSNPS-SSAGTPSPEEEEEEEEEE 277
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 39.3 bits (90), Expect = 0.007
Identities = 38/145 (26%), Positives = 50/145 (34%), Gaps = 17/145 (11%)
Query: 37 HFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPPF---EGQSQVQPPPSQEATPLQQEKLLP 93
+ Q++ PP+P L P PP + Q Q QPPP P
Sbjct: 931 YLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPP----- 985
Query: 94 AQLPAEKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPESWNAAQHCQQ 153
P ++ PP P P+Q Q P Q + P P Q P P+ Q Q
Sbjct: 986 ---PQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQH 1042
Query: 154 DRSQGGWGHRLDGFPPGR----PSP 174
S H+ D + G PSP
Sbjct: 1043 HHSPR--HHKSDPYSTGHLREAPSP 1065
Score = 33.9 bits (76), Expect = 0.28
Identities = 34/144 (23%), Positives = 50/144 (34%), Gaps = 17/144 (11%)
Query: 16 VASAASEGGFTATGQRQLRPEHFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQV 75
+A + + G Q++ H Q++ A P +P P Q PP Q
Sbjct: 721 MAPKSKKKGHPGREQKKHHHHHHQQMQQAPAP-------VPQQPPPPPQQPPPPPPPQQQ 773
Query: 76 QPPPSQEATPLQQEKLLPAQLPAEKEVGPPLPQEAVP-LQKELPS-----LQHPNEQKEG 129
Q PP P ++ PA K PP VP L+ +LP + H +
Sbjct: 774 QQPPPPPPPPSMPQQAAPAM----KSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILH 829
Query: 130 TPAPFGDQSHPEPESWNAAQHCQQ 153
P P P+P + H Q
Sbjct: 830 LPQPELPPHLPQPPEHSTPPHLNQ 853
Score = 32.3 bits (72), Expect = 0.81
Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 17/134 (12%)
Query: 15 AVASAASEGGFTATGQRQLRPEH----FQEVGYAAPPSPPLSR-SLPMDHPDSSQHG-PP 68
A A +S F AT L P+ F +G+ P L + LP P +H PP
Sbjct: 790 APAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPP 849
Query: 69 FEGQSQVQPPPS-------QEATPLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELPSLQ 121
Q V PP+ Q + P + LP + V P L Q PL + P Q
Sbjct: 850 HLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQ--TPLLPQPPMAQ 907
Query: 122 HPNE--QKEGTPAP 133
P + E PAP
Sbjct: 908 PPQVLLEDEEPPAP 921
Score = 31.6 bits (70), Expect = 1.4
Identities = 25/81 (30%), Positives = 34/81 (41%), Gaps = 5/81 (6%)
Query: 60 PDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELPS 119
P+++Q P + Q+ PP +ATP PA P + V P+ P + P
Sbjct: 197 PNTTQASTPPQTQTPQPNPPPVQATPHP----FPAVTP-DLIVQTPVMTVVPPQPLQTPP 251
Query: 120 LQHPNEQKEGTPAPFGDQSHP 140
P Q PAP QSHP
Sbjct: 252 PVPPQPQPPPAPAPQPVQSHP 272
Score = 29.3 bits (64), Expect = 6.9
Identities = 20/86 (23%), Positives = 34/86 (39%), Gaps = 11/86 (12%)
Query: 98 AEKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPESWNAAQHCQQDRSQ 157
+E E+ P ++ P +++ H ++Q + PAP Q P P+ QQ +
Sbjct: 717 SETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQ- 775
Query: 158 GGWGHRLDGFPPGRPSPDNLNQICLP 183
PP P P ++ Q P
Sbjct: 776 ----------PPPPPPPPSMPQQAAP 791
>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
[Homo sapiens]
Length = 1285
Score = 39.3 bits (90), Expect = 0.007
Identities = 41/155 (26%), Positives = 56/155 (36%), Gaps = 28/155 (18%)
Query: 45 APPSPPLSRSLPMDHPDSSQH-GPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVG 103
+P P S S + P + H P +G+ + ++ T ++L P E
Sbjct: 769 SPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPG------EAL 822
Query: 104 PPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHP-EPESWNAAQHCQQDRSQGGWGH 162
PP+ Q ELPS P P+P P P W Q+RS GG
Sbjct: 823 PPVSQAGTGKAPELPSGSGPEPL---APSPVSPTFPPSSPSDW------PQERSPGG--- 870
Query: 163 RLDGFPPGRPSPDNLNQICLPNRQHVVYGPWNLPQ 197
DG P P P LP +H PW P+
Sbjct: 871 HSDGASPRSPVPTT-----LPGLRH---APWQGPR 897
>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
[Homo sapiens]
Length = 1409
Score = 39.3 bits (90), Expect = 0.007
Identities = 41/155 (26%), Positives = 56/155 (36%), Gaps = 28/155 (18%)
Query: 45 APPSPPLSRSLPMDHPDSSQH-GPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVG 103
+P P S S + P + H P +G+ + ++ T ++L P E
Sbjct: 893 SPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPG------EAL 946
Query: 104 PPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHP-EPESWNAAQHCQQDRSQGGWGH 162
PP+ Q ELPS P P+P P P W Q+RS GG
Sbjct: 947 PPVSQAGTGKAPELPSGSGPEPL---APSPVSPTFPPSSPSDW------PQERSPGG--- 994
Query: 163 RLDGFPPGRPSPDNLNQICLPNRQHVVYGPWNLPQ 197
DG P P P LP +H PW P+
Sbjct: 995 HSDGASPRSPVPTT-----LPGLRH---APWQGPR 1021
>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
[Homo sapiens]
Length = 1419
Score = 39.3 bits (90), Expect = 0.007
Identities = 41/155 (26%), Positives = 56/155 (36%), Gaps = 28/155 (18%)
Query: 45 APPSPPLSRSLPMDHPDSSQH-GPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVG 103
+P P S S + P + H P +G+ + ++ T ++L P E
Sbjct: 903 SPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPG------EAL 956
Query: 104 PPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHP-EPESWNAAQHCQQDRSQGGWGH 162
PP+ Q ELPS P P+P P P W Q+RS GG
Sbjct: 957 PPVSQAGTGKAPELPSGSGPEPL---APSPVSPTFPPSSPSDW------PQERSPGG--- 1004
Query: 163 RLDGFPPGRPSPDNLNQICLPNRQHVVYGPWNLPQ 197
DG P P P LP +H PW P+
Sbjct: 1005 HSDGASPRSPVPTT-----LPGLRH---APWQGPR 1031
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 39.3 bits (90), Expect = 0.007
Identities = 47/165 (28%), Positives = 57/165 (34%), Gaps = 17/165 (10%)
Query: 30 QRQLRPEHFQEVGYAAPPSPPLSRSLPMDH--PDSSQHGPPFEGQSQVQPPPSQEATPLQ 87
QR P +P + PL R P + Q PP G Q P P ++ PLQ
Sbjct: 423 QRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQ 482
Query: 88 QEKLLPAQLPAEKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPESWNA 147
Q P Q ++ + P PL + LPS T AP S P +
Sbjct: 483 QRP--PPQ--GQQHLSGLGPPAGSPLPQRLPS---------PTSAPQQPASQAAPPT--Q 527
Query: 148 AQHCQQDRSQGGWGHRLDGFPPGRPSPDNLNQICLPNRQHVVYGP 192
Q Q GG G PP PSP RQ V GP
Sbjct: 528 GQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGP 572
Score = 32.3 bits (72), Expect = 0.81
Identities = 35/136 (25%), Positives = 45/136 (33%), Gaps = 18/136 (13%)
Query: 39 QEVGYAAPPSPPLSRSLPMDHPDSSQHGPPFEGQSQVQPPPSQEATPLQQEKLLPAQLPA 98
Q AAPP+ R P + G P + P P ++A P Q + PA
Sbjct: 517 QPASQAAPPTQGQGRQ---SRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPA 573
Query: 99 EKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPESWNAAQHCQQDRSQG 158
PP A P ++ Q P ++ G P S P QQ R G
Sbjct: 574 -----PPKASGAPPGGQQ---RQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSG 625
Query: 159 GWGHRLDGFPPGRPSP 174
P GRP P
Sbjct: 626 PG-------PAGRPKP 634
Score = 28.9 bits (63), Expect = 9.0
Identities = 28/115 (24%), Positives = 34/115 (29%), Gaps = 11/115 (9%)
Query: 30 QRQLRPEHFQEVGYAAPPSPPLSRSLPMDHPDSSQH-GPPFEGQSQVQPPPSQEATPLQQ 88
QRQ P + P+PP + P P Q GPP Q PP Q
Sbjct: 555 QRQAGPPQATRQTSVSGPAPPKASGAP---PGGQQRQGPP-------QKPPGPAGPTRQA 604
Query: 89 EKLLPAQLPAEKEVGPPLPQEAVPLQKELPSLQHPNEQKEGTPAPFGDQSHPEPE 143
+ P P P P + P L Q PA P P+
Sbjct: 605 SQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQ 659
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,870,121
Number of Sequences: 37866
Number of extensions: 1359390
Number of successful extensions: 7198
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 594
Number of HSP's that attempted gapping in prelim test: 5544
Number of HSP's gapped (non-prelim): 1747
length of query: 415
length of database: 18,247,518
effective HSP length: 105
effective length of query: 310
effective length of database: 14,271,588
effective search space: 4424192280
effective search space used: 4424192280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.