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Search of human proteins with 221316584
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221316584 BSD domain containing 1 isoform c [Homo sapiens]
(374 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221316584 BSD domain containing 1 isoform c [Homo sapiens] 756 0.0
gi|221316578 BSD domain containing 1 isoform b [Homo sapiens] 680 0.0
gi|221316586 BSD domain containing 1 isoform d [Homo sapiens] 664 0.0
gi|221316581 BSD domain containing 1 isoform a [Homo sapiens] 637 0.0
gi|163965366 nascent polypeptide-associated complex alpha subuni... 49 1e-05
gi|110349719 titin isoform N2-A [Homo sapiens] 47 2e-05
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 44 3e-04
gi|74136549 AT rich interactive domain 5B (MRF1-like) [Homo sapi... 40 0.003
gi|55749621 pleckstrin homology domain containing, family G, mem... 40 0.003
gi|38372931 brevican isoform 2 [Homo sapiens] 39 0.006
gi|38372935 brevican isoform 1 [Homo sapiens] 39 0.006
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 39 0.008
gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo ... 39 0.008
gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo ... 39 0.008
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 39 0.010
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 39 0.010
gi|134031945 SCO-spondin [Homo sapiens] 39 0.010
gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi... 38 0.013
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 38 0.013
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 38 0.013
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 38 0.013
gi|33286444 mastermind-like 2 [Homo sapiens] 38 0.013
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 38 0.013
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 38 0.017
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 38 0.017
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] 38 0.017
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] 37 0.022
gi|40807452 peroxisome proliferator-activated receptor gamma, co... 37 0.029
gi|154800453 tastin isoform 1 [Homo sapiens] 37 0.029
gi|4502483 Ras association (RalGDS/AF-6) domain family (N-termin... 37 0.038
>gi|221316584 BSD domain containing 1 isoform c [Homo sapiens]
Length = 374
Score = 756 bits (1951), Expect = 0.0
Identities = 374/374 (100%), Positives = 374/374 (100%)
Query: 1 MAEGEDVGWWRSWLQQSYQAVKEKSSEALEFMKRDLTEFTQVVQHDTACTIAATASVVKE 60
MAEGEDVGWWRSWLQQSYQAVKEKSSEALEFMKRDLTEFTQVVQHDTACTIAATASVVKE
Sbjct: 1 MAEGEDVGWWRSWLQQSYQAVKEKSSEALEFMKRDLTEFTQVVQHDTACTIAATASVVKE 60
Query: 61 KLAARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKM 120
KLAARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKM
Sbjct: 61 KLAARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKM 120
Query: 121 VPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISP 180
VPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISP
Sbjct: 121 VPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISP 180
Query: 181 KEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAP 240
KEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAP
Sbjct: 181 KEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAP 240
Query: 241 EARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVET 300
EARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVET
Sbjct: 241 EARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVET 300
Query: 301 LREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVD 360
LREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVD
Sbjct: 301 LREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVD 360
Query: 361 ASGELEDVEWEDWE 374
ASGELEDVEWEDWE
Sbjct: 361 ASGELEDVEWEDWE 374
>gi|221316578 BSD domain containing 1 isoform b [Homo sapiens]
Length = 430
Score = 680 bits (1754), Expect = 0.0
Identities = 354/430 (82%), Positives = 358/430 (83%), Gaps = 56/430 (13%)
Query: 1 MAEGEDVGWWRSWLQQSYQAVKEKSSEALEFMKRD------------------------- 35
MAEGEDVGWWRSWLQQSYQAVKEKSSEALEFMKRD
Sbjct: 1 MAEGEDVGWWRSWLQQSYQAVKEKSSEALEFMKRDLTEFTQVVQHDTACTIAATASVVKE 60
Query: 36 -----------------LTEFTQVVQHDTA-----------CTIAATASVVKEKL---AA 64
L++F V+ A T+ T S E A
Sbjct: 61 KLATEGSSGATEKMKKGLSDFLGVISDTFAPSPDKTIDCDVITLMGTPSGTAEPYDGTKA 120
Query: 65 RLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKMVPAA 124
RLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKMVPAA
Sbjct: 121 RLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKMVPAA 180
Query: 125 VSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKEAK 184
VSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKEAK
Sbjct: 181 VSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKEAK 240
Query: 185 VPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARV 244
VPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARV
Sbjct: 241 VPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARV 300
Query: 245 LPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLREE 304
LPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLREE
Sbjct: 301 LPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLREE 360
Query: 305 APTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDASGE 364
APTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDASGE
Sbjct: 361 APTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDASGE 420
Query: 365 LEDVEWEDWE 374
LEDVEWEDWE
Sbjct: 421 LEDVEWEDWE 430
>gi|221316586 BSD domain containing 1 isoform d [Homo sapiens]
Length = 335
Score = 664 bits (1712), Expect = 0.0
Identities = 335/374 (89%), Positives = 335/374 (89%), Gaps = 39/374 (10%)
Query: 1 MAEGEDVGWWRSWLQQSYQAVKEKSSEALEFMKRDLTEFTQVVQHDTACTIAATASVVKE 60
MAEGEDVGWWRSWLQQSYQAVKEK
Sbjct: 1 MAEGEDVGWWRSWLQQSYQAVKEK------------------------------------ 24
Query: 61 KLAARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKM 120
ARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKM
Sbjct: 25 ---ARLYSLQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKM 81
Query: 121 VPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISP 180
VPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISP
Sbjct: 82 VPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISP 141
Query: 181 KEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAP 240
KEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAP
Sbjct: 142 KEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAP 201
Query: 241 EARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVET 300
EARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVET
Sbjct: 202 EARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVET 261
Query: 301 LREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVD 360
LREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVD
Sbjct: 262 LREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVD 321
Query: 361 ASGELEDVEWEDWE 374
ASGELEDVEWEDWE
Sbjct: 322 ASGELEDVEWEDWE 335
>gi|221316581 BSD domain containing 1 isoform a [Homo sapiens]
Length = 447
Score = 637 bits (1643), Expect = 0.0
Identities = 326/366 (89%), Positives = 331/366 (90%), Gaps = 14/366 (3%)
Query: 23 EKSSEALEFMKRDLTEFTQVVQHDTA-----------CTIAATASVVKEKL---AARLYS 68
E SS A E MK+ L++F V+ A T+ T S E ARLYS
Sbjct: 82 EGSSGATEKMKKGLSDFLGVISDTFAPSPDKTIDCDVITLMGTPSGTAEPYDGTKARLYS 141
Query: 69 LQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKMVPAAVSHS 128
LQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKMVPAAVSHS
Sbjct: 142 LQSDPATYCNEPDGPPELFDAWLSQFCLEEKKGEISELLVGSPSIRALYTKMVPAAVSHS 201
Query: 129 EFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKEAKVPVA 188
EFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKEAKVPVA
Sbjct: 202 EFWHRYFYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKEAKVPVA 261
Query: 189 KISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKD 248
KISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKD
Sbjct: 262 KISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKD 321
Query: 249 LSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLREEAPTD 308
LSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLREEAPTD
Sbjct: 322 LSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLREEAPTD 381
Query: 309 LRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDASGELEDV 368
LRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDASGELEDV
Sbjct: 382 LRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDASGELEDV 441
Query: 369 EWEDWE 374
EWEDWE
Sbjct: 442 EWEDWE 447
Score = 129 bits (325), Expect = 3e-30
Identities = 63/63 (100%), Positives = 63/63 (100%)
Query: 1 MAEGEDVGWWRSWLQQSYQAVKEKSSEALEFMKRDLTEFTQVVQHDTACTIAATASVVKE 60
MAEGEDVGWWRSWLQQSYQAVKEKSSEALEFMKRDLTEFTQVVQHDTACTIAATASVVKE
Sbjct: 1 MAEGEDVGWWRSWLQQSYQAVKEKSSEALEFMKRDLTEFTQVVQHDTACTIAATASVVKE 60
Query: 61 KLA 63
KLA
Sbjct: 61 KLA 63
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 48.5 bits (114), Expect = 1e-05
Identities = 48/173 (27%), Positives = 77/173 (44%), Gaps = 21/173 (12%)
Query: 172 LMGISPISPKEAKVPV-AKISTFPEGEPGPQSPCEENLVTSVEP--PAEV--TPSESSES 226
L ++P SPKE P S+ P+ P +P + +V P P EV TPS +
Sbjct: 1467 LPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDP 1526
Query: 227 ISLVTQIAN---PAT-APEARVLPKDLS----QKLLEASLEEQGLAVDVGETGPSPPIHS 278
I+ + + PAT AP+ ++P ++ +K ++ A + SPP
Sbjct: 1527 IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPA-- 1584
Query: 279 KPLTPAGHTGGPEPR----PPARVETLREEAPTDLRVFELNSDSGKSTPSNNG 327
+TP+ + G P P+ PPA +EAPT V + + G +TP+ G
Sbjct: 1585 --VTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKG 1635
Score = 37.4 bits (85), Expect = 0.022
Identities = 36/128 (28%), Positives = 48/128 (37%), Gaps = 11/128 (8%)
Query: 179 SPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPA-----EVTPSESSESISLVTQI 233
SPK A P A P+G P SP +V PP+ TP S
Sbjct: 981 SPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP 1040
Query: 234 ANPATAPEARVLPKDL-SQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEP 292
+P +P A LPK + + G A + P+PP + P +P G P P
Sbjct: 1041 PSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP-SPKGGPATPSP 1099
Query: 293 R----PPA 296
+ PPA
Sbjct: 1100 KGAPMPPA 1107
Score = 36.6 bits (83), Expect = 0.038
Identities = 44/156 (28%), Positives = 60/156 (38%), Gaps = 25/156 (16%)
Query: 174 GISPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQI 233
G++ SPK A P +T P + GP +P + T PPA PS L T
Sbjct: 1231 GLATPSPKGA--PTTPAATPPSPKGGPATPPPKGAPT---PPAATPPSLKG---GLATPP 1282
Query: 234 ANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPR 293
A P P + G A + P+PP + P +P G G P P+
Sbjct: 1283 HKGAPNPAVVTPPS-----------PKGGPATSPPKGAPTPPAATPP-SPKGSPGTPPPK 1330
Query: 294 ----PPARVETLREEAPTDLRVFELNSDSGKSTPSN 325
PPA + PT L +S G +TPS+
Sbjct: 1331 GAPTPPAVTPPSPKGTPT-LPATTPSSKGGPTTPSS 1365
Score = 35.8 bits (81), Expect = 0.064
Identities = 43/163 (26%), Positives = 58/163 (35%), Gaps = 40/163 (24%)
Query: 180 PKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATA 239
PK A P A P+G PG P P VTP + +L PAT
Sbjct: 1306 PKGAPTPPAATPPSPKGSPGTPPP------KGAPTPPAVTPPSPKGTPTL------PATT 1353
Query: 240 PEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVE 299
P ++ P S K GP+PP TP+ H GGP PP+
Sbjct: 1354 PSSKGGPTTPSSK-----------------EGPTPP----AATPS-HKGGPAMTPPSPKR 1391
Query: 300 ----TLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISED 338
+ PT V L+ +TP ++G++T D
Sbjct: 1392 GPAIPSPKGDPTSPAVIPLSPKKAPATPVT--REGAATPSKGD 1432
Score = 34.3 bits (77), Expect = 0.19
Identities = 43/159 (27%), Positives = 58/159 (36%), Gaps = 15/159 (9%)
Query: 176 SPISPKEAKVPVAKISTFPEGEPGP----QSPCEENLVTSVEPPAEVTPSESSESISLVT 231
+P SPK A P A P+G P +P NL E PA P + + ++S+ +
Sbjct: 857 TPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ-APALSMTS 915
Query: 232 QIANPATA-PEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKP--LTPAGHTG 288
A A P + +P S K + G PSP P TP G
Sbjct: 916 SSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKG 975
Query: 289 GPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNG 327
GP P + APT + G +TPS G
Sbjct: 976 GPATPSP-------KGAPTPPAATPPSPKGGPATPSPKG 1007
Score = 34.3 bits (77), Expect = 0.19
Identities = 41/143 (28%), Positives = 58/143 (40%), Gaps = 22/143 (15%)
Query: 179 SPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIA--NP 236
SPKEA P A T P E GP +P + TS PP VTPS +S + +
Sbjct: 1609 SPKEAPTPPAV--TPPSPEKGPATPAPKGTPTS--PP--VTPSSLKDSPTSPASVTCKMG 1662
Query: 237 ATAPE------ARVLPKDLSQKLLEASLEEQGLAVDVGETGP--------SPPIHSKPLT 282
AT P+ A+ P L + L+ + E + GP SPPI P
Sbjct: 1663 ATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSA 1722
Query: 283 PAGHTGGPEPRPPARVETLREEA 305
G G PA + +++++
Sbjct: 1723 KNGSKGPLSTVAPAPLLPVQKDS 1745
Score = 33.9 bits (76), Expect = 0.24
Identities = 44/156 (28%), Positives = 52/156 (33%), Gaps = 19/156 (12%)
Query: 179 SPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPAT 238
SPK A P A P+G P SP + PPA PS T A
Sbjct: 935 SPKGAPTPPAATPPSPKGGPATPSP-----KWAPTPPAATPPSPKG---GPATPSPKGAP 986
Query: 239 APEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSP-------PIHSKPLTPAGHTGGPE 291
P A P S K A+ +G T PSP P TP T P
Sbjct: 987 TPPAATPP---SPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT-PPS 1042
Query: 292 PRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNG 327
P+ L + APT + G +TPS G
Sbjct: 1043 PKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG 1078
Score = 33.1 bits (74), Expect = 0.42
Identities = 29/91 (31%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 186 PVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVT---QIANPATAPEA 242
P K +T PQ+P +L V PPA + S S++S+ +VT + A P T P+
Sbjct: 244 PQVKDTTISSVLISPQNPGSLSLKGPVSPPAAL--SLSTQSLPVVTSSQKTAGPNTPPD- 300
Query: 243 RVLPKDLSQKLLEASLEEQGLAVDVGETGPS 273
P L L G +G+TGPS
Sbjct: 301 --FPISLGSHLAPLHQSSFGSVQLLGQTGPS 329
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 47.4 bits (111), Expect = 2e-05
Identities = 54/197 (27%), Positives = 82/197 (41%), Gaps = 22/197 (11%)
Query: 142 EQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKEAKVPVAKISTFPEGEPGPQ 201
E+E + + E EE EEEE L + P+E ++P + PE E P+
Sbjct: 10104 EEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPE 10163
Query: 202 SP---CEENLVTSVEPPAEVTPSESSESISLVTQ----IANPATAPEARV--LPKDLSQK 252
EE ++ V+P V P+ E VT+ I AP A+V +PK + +K
Sbjct: 10164 EEEFVPEEEVLPEVKPKVPV-PAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEK 10222
Query: 253 LLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLREEAPTDLRVF 312
+ EE+ L V+V E PI + + P P +E + E AP RV
Sbjct: 10223 RIILPKEEEVLPVEVTEEPEEEPISEEEI----------PEEPPSIEEVEEVAPP--RVP 10270
Query: 313 ELNSDSGKSTPSNNGKK 329
E+ + P+ KK
Sbjct: 10271 EVIKKAVPEAPTPVPKK 10287
Score = 33.1 bits (74), Expect = 0.42
Identities = 49/197 (24%), Positives = 72/197 (36%), Gaps = 31/197 (15%)
Query: 137 KVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGIS-PISPK----EAKVPVAKIS 191
+V++ +E A + + E+ + P EEEE E+ + P PK E KVPV K
Sbjct: 10802 EVYEEPEEIAPEEEIAPEEEKPV---PVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKP 10858
Query: 192 TFPEG-EPGPQSPCEE-NLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKDL 249
P EP P+ E+ L PP P E + + PE +P+ +
Sbjct: 10859 EAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKV 10918
Query: 250 SQKLLEASLEEQGLAVDVGETGPSPP-------------------IHSKPLTPAGHTGGP 290
L+ E+ + + E P P + K L P
Sbjct: 10919 ELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVP 10978
Query: 291 EPRPPARVETLREEAPT 307
EP PP VE + E PT
Sbjct: 10979 EPPPPKPVEEV--EVPT 10993
Score = 31.6 bits (70), Expect = 1.2
Identities = 42/162 (25%), Positives = 62/162 (38%), Gaps = 23/162 (14%)
Query: 156 EQSISEEPGWEEEEEELMGISPISPKEAK-VPVAKISTFPEGEP-----GPQSPCEENLV 209
E++ S P EE EE+ I+P+E K VPVA+ PE P P+ E V
Sbjct: 10794 ERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAE-EEEPEVPPPAVPEEPKKIIPEKKV 10852
Query: 210 TSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPK-DLSQKLLEASLEEQGLAVDVG 268
++ P P E + P P PK D+ +K+ + A+
Sbjct: 10853 PVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLK------AIPKK 10906
Query: 269 ETGPSPPIHSK-PLTPAGHTGG--------PEPRPPARVETL 301
+ P + K LTP GG PE +P + E +
Sbjct: 10907 KVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVV 10948
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 43.5 bits (101), Expect = 3e-04
Identities = 51/192 (26%), Positives = 76/192 (39%), Gaps = 32/192 (16%)
Query: 155 AEQSISEEPGWEEE---EEELMGISPISPKEA-------------------KVPVAKIST 192
AE ++ E P E EE L + P+ P+EA + P S
Sbjct: 401 AEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAPTEFQSP 460
Query: 193 FPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKDLSQK 252
P+ ++ E L+ + EPPA+ TP+E+ +S T A A A L ++ + +
Sbjct: 461 LPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETS-AEEAHAEVQSPLAEETTAE 519
Query: 253 LLEASLEEQGLAVDVGETGPSPPIHSKPLT--PAGHTGGPEPRPPARVETLREEAPTDLR 310
EAS E Q LA +P PL+ + E + P+ EEAP
Sbjct: 520 --EASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAP---- 573
Query: 311 VFELNSDSGKST 322
EL SG+ T
Sbjct: 574 -LELQPPSGEET 584
Score = 41.6 bits (96), Expect = 0.001
Identities = 81/386 (20%), Positives = 141/386 (36%), Gaps = 58/386 (15%)
Query: 13 WLQQSYQAVKEKSSEALEFMKRDLTEFTQVVQHDTACTIAATASVVKEKLAARLYSLQS- 71
W + V++ E + +E + + D++ T + +K K + ++++ +
Sbjct: 140 WTMMNIPPVEKVDKEQQTYFSE--SEIVVISRPDSSST-KSKEDALKHKSSGKIFASEHP 196
Query: 72 --DPATYCNEPDGPPELFDAWLSQFCLEEKKG-------EISELLVGSPSIRALYTKMVP 122
PAT NE G + + F E KKG E+ E + K V
Sbjct: 197 EFQPATNSNEEIGQKNISR---TSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVA 253
Query: 123 AAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAEQS-ISEEPGWEE--EEEELMGISPIS 179
+A ++ K+ E+A A + AE++ + +P EE + E ++ S
Sbjct: 254 SAEIEPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENS 313
Query: 180 PKEAKVPV--AKISTFPEGEPGP---QSPCEENLVTSVEPPAEVTPS------------E 222
K P A + FP P +SP E L + P AE +PS E
Sbjct: 314 VKVQPPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAE 373
Query: 223 SSESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVD--------------VG 268
S S+ L+ +I +P+ A+ P ++ E +LEE V+ +
Sbjct: 374 KSPSVELLGEIRSPS----AQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLP 429
Query: 269 ETGPSPPIHSKPLTPAGHTGGPEP----RPPARVETLREEAPTDLRVFELNSDSGKSTPS 324
E P L+ A T E + P ET EEA ++++ TP+
Sbjct: 430 EEAPREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPA 489
Query: 325 NNGKKGSSTDISEDWEKDFDLDMTEE 350
S +E+ + + EE
Sbjct: 490 EARSPLSEETSAEEAHAEVQSPLAEE 515
Score = 35.0 bits (79), Expect = 0.11
Identities = 53/229 (23%), Positives = 80/229 (34%), Gaps = 27/229 (11%)
Query: 97 EEKKGEISELLVGSPSIRALYTKMVPAAVSHSEFWHRYFYKVHQLEQEQARRDALKQRAE 156
EE E + V SPS + + + P + + Q A +A + A
Sbjct: 548 EETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAP 607
Query: 157 QSISEEPGWEEEEEELMGISPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPA 216
+ P E E + P +EA V + P ++P E + E PA
Sbjct: 608 AEVQPPPAEEAPAE----VQPPPAEEAPAEV-------QPPPAEEAPAEVQPPPAEEAPA 656
Query: 217 EVTPSESSESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPI 276
EV P + E+ + V E + LP + E +EE AV SPP
Sbjct: 657 EVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAE------ETPIEETLAAVH------SPPA 704
Query: 277 HSKPLTPAGHTGGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSN 325
PA + PPA + L EE P E++ + TP +
Sbjct: 705 DD---VPAEEASVDKHSPPADL-LLTEEFPIGEASAEVSPPPSEQTPED 749
Score = 30.0 bits (66), Expect = 3.5
Identities = 36/149 (24%), Positives = 59/149 (39%), Gaps = 21/149 (14%)
Query: 144 EQARRDALKQRAEQSISE--EPGWEEEEEELMGISPISPKEAKVPVAKISTFPEGEPGPQ 201
E+A + AE++ +E P EE E + P A+ A++ + P E
Sbjct: 640 EEAPAEVQPPPAEEAPAEVQPPPAEEAPAE------VQPPPAEEAPAEVQSLPAEE---- 689
Query: 202 SPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLP-----KDLSQKLLEA 256
+P EE L PPA+ P+E + V + + PA P ++S E
Sbjct: 690 TPIEETLAAVHSPPADDVPAEEAS----VDKHSPPADLLLTEEFPIGEASAEVSPPPSEQ 745
Query: 257 SLEEQGLAVDVGETGPSPPIHSKPLTPAG 285
+ E++ L +V SP + P G
Sbjct: 746 TPEDEALVENVSTEFQSPQVAGIPAVKLG 774
>gi|74136549 AT rich interactive domain 5B (MRF1-like) [Homo
sapiens]
Length = 1188
Score = 40.0 bits (92), Expect = 0.003
Identities = 35/128 (27%), Positives = 58/128 (45%), Gaps = 24/128 (18%)
Query: 200 PQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPK-----DLSQKLL 254
P+S E+ + AEV+ + E +L++Q + P P A + K + S K L
Sbjct: 449 PKSKKEKENAPKPQDAAEVSSEQEKEQETLISQKSIPEPLPAADMKKKIEGYQEFSAKPL 508
Query: 255 EASLE-------EQG-----LAVDVGETGPSPPIHSKPLTP-------AGHTGGPEPRPP 295
+ ++ +QG +A + GE GP+PP+ S PL P G + P P
Sbjct: 509 ASRVDPEKDNETDQGSNSEKVAEEAGEKGPTPPLPSAPLAPEKDSALVPGASKQPLTSPS 568
Query: 296 ARVETLRE 303
A V++ +E
Sbjct: 569 ALVDSKQE 576
>gi|55749621 pleckstrin homology domain containing, family G, member
3 [Homo sapiens]
Length = 1163
Score = 40.0 bits (92), Expect = 0.003
Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 8/98 (8%)
Query: 139 HQLEQ--EQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKEAKVPVAKISTFPEG 196
H L Q E+AR +K + + E G SP S E ++ IS+ PE
Sbjct: 397 HLLRQLNEKARAAGMKGKGRR----ESESSRSSRRPSGRSPTST-EKRMSFESISSLPEV 451
Query: 197 EPGPQSPCEENLVTSVE-PPAEVTPSESSESISLVTQI 233
EP P++ E+ + ++VE P AE TPS++ L TQ+
Sbjct: 452 EPDPEAGSEQEVFSAVEGPSAEETPSDTESPEVLETQL 489
>gi|38372931 brevican isoform 2 [Homo sapiens]
Length = 671
Score = 39.3 bits (90), Expect = 0.006
Identities = 49/185 (26%), Positives = 71/185 (38%), Gaps = 13/185 (7%)
Query: 142 EQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKEAKVPVAKISTFPEGEPGPQ 201
E+ +A + K E+ EE EE E+E + P S + P A + T P +
Sbjct: 448 EEGKALEEEEKYEDEEEKEEEEEEEEVEDEALWAWP-SELSSPGPEASLPTEPAAQEESL 506
Query: 202 SPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQ 261
S V ++P A P SE+ S ++ P T LP + L S
Sbjct: 507 SQAPARAV--LQPGASPLPDGESEA-SRPPRVHGPPT----ETLPTPRERNLASPSPSTL 559
Query: 262 GLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLREEAPTDLRVFELNSD--SG 319
A +VGE P + P + TG E P T AP R E S+ SG
Sbjct: 560 VEAREVGEATGGPELSGVPRGESEETGSSEGAPSLLPAT---RAPEGTRELEAPSEDNSG 616
Query: 320 KSTPS 324
++ P+
Sbjct: 617 RTAPA 621
Score = 33.9 bits (76), Expect = 0.24
Identities = 33/127 (25%), Positives = 57/127 (44%), Gaps = 12/127 (9%)
Query: 228 SLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHT 287
S + + +NPA+ P + L ++ + +LEE L + E+ I+S P+ G
Sbjct: 360 SAIPEASNPASNPASDGLEAIVT---VTETLEELQLPQEATESESRGAIYSIPIMEDGGG 416
Query: 288 GGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDM 347
G P PA EAP L FE S + S ++G + + E +E + + +
Sbjct: 417 GSSTPEDPA-------EAPRTLLEFETQSMVPPTGFSE--EEGKALEEEEKYEDEEEKEE 467
Query: 348 TEEEVQM 354
EEE ++
Sbjct: 468 EEEEEEV 474
>gi|38372935 brevican isoform 1 [Homo sapiens]
Length = 911
Score = 39.3 bits (90), Expect = 0.006
Identities = 49/185 (26%), Positives = 71/185 (38%), Gaps = 13/185 (7%)
Query: 142 EQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKEAKVPVAKISTFPEGEPGPQ 201
E+ +A + K E+ EE EE E+E + P S + P A + T P +
Sbjct: 448 EEGKALEEEEKYEDEEEKEEEEEEEEVEDEALWAWP-SELSSPGPEASLPTEPAAQEESL 506
Query: 202 SPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQ 261
S V ++P A P SE+ S ++ P T LP + L S
Sbjct: 507 SQAPARAV--LQPGASPLPDGESEA-SRPPRVHGPPT----ETLPTPRERNLASPSPSTL 559
Query: 262 GLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLREEAPTDLRVFELNSD--SG 319
A +VGE P + P + TG E P T AP R E S+ SG
Sbjct: 560 VEAREVGEATGGPELSGVPRGESEETGSSEGAPSLLPAT---RAPEGTRELEAPSEDNSG 616
Query: 320 KSTPS 324
++ P+
Sbjct: 617 RTAPA 621
Score = 33.9 bits (76), Expect = 0.24
Identities = 33/127 (25%), Positives = 57/127 (44%), Gaps = 12/127 (9%)
Query: 228 SLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHT 287
S + + +NPA+ P + L ++ + +LEE L + E+ I+S P+ G
Sbjct: 360 SAIPEASNPASNPASDGLEAIVT---VTETLEELQLPQEATESESRGAIYSIPIMEDGGG 416
Query: 288 GGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDM 347
G P PA EAP L FE S + S ++G + + E +E + + +
Sbjct: 417 GSSTPEDPA-------EAPRTLLEFETQSMVPPTGFSE--EEGKALEEEEKYEDEEEKEE 467
Query: 348 TEEEVQM 354
EEE ++
Sbjct: 468 EEEEEEV 474
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 38.9 bits (89), Expect = 0.008
Identities = 50/223 (22%), Positives = 84/223 (37%), Gaps = 44/223 (19%)
Query: 135 FYKVHQLEQEQARRDALKQRAEQSISEEPGWEEEEEELMGISPI----SPKEAKVPVAKI 190
+++ + E+E+ + ++ E EE EEEEEEL + + + E +
Sbjct: 920 YFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPP 979
Query: 191 STFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKDLS 250
T P P P+SP V+P E P L+ ++ P T E D +
Sbjct: 980 PTLPPALPPPESP------PKVQPEPEPEP-------GLLLEVEEPGTEEERGA---DTA 1023
Query: 251 QKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVETLREEAPTDLR 310
L +L QG +V G SP GP P+ E + EE
Sbjct: 1024 PTLAPEALPSQG---EVEREGESP------------AAGPPPQ-----ELVEEEPSAPPT 1063
Query: 311 VFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDLDMTEEEVQ 353
+ E ++ G S+ + T E+ E + + + +E+ Q
Sbjct: 1064 LLEEETEDG----SDKVQPPPETPAEEEMETETEAEALQEKEQ 1102
Score = 32.7 bits (73), Expect = 0.54
Identities = 51/220 (23%), Positives = 75/220 (34%), Gaps = 49/220 (22%)
Query: 194 PEGEPGPQSPCEENLVTSVEPPAEV-------------TPSESSESISLVTQIANP---- 236
P G P P P +E V PA V S+S +S+ +V + P
Sbjct: 742 PSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPP 801
Query: 237 ----ATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPP----------IHSKPLT 282
AT P + + A E + L G P PP + L
Sbjct: 802 PPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLV 861
Query: 283 PAGHTGGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDW--- 339
P G GG P PA E DL V +NS + ++ + E+
Sbjct: 862 PEGTPGGGGP--PALEE--------DLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFE 911
Query: 340 -----EKDFDLDMTEEEVQMALSKVDASGELEDVEWEDWE 374
E+++ + EEE + + GELE+ E E+ E
Sbjct: 912 EEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDE 951
>gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo
sapiens]
Length = 788
Score = 38.9 bits (89), Expect = 0.008
Identities = 52/186 (27%), Positives = 77/186 (41%), Gaps = 35/186 (18%)
Query: 142 EQEQARRDALKQRAEQSISEEPGWEEEE--EELMGISPISPKEAKVPVAKI--------- 190
E+E+A++ K A+ +E E E+ E M IS K A+ P K+
Sbjct: 153 EKEEAKKTEDKSLAKPETDKEQDSEMEKGGREDMDIS----KSAEEPQEKVDLTLDWLTE 208
Query: 191 -STFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVT----------QIANPATA 239
S +G P+ P E VTS +P EV +E +S+S Q
Sbjct: 209 TSEEAKGGAAPEGPNEAE-VTSGKPEQEVPDAEEEKSVSGTDVQEECREKGGQEKQGEVI 267
Query: 240 PEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVE 299
PK++S++ +LE+QG AV+V P + KP+ GG EP +V
Sbjct: 268 VSIEEKPKEVSEEQPVVTLEKQGTAVEVEAESLDPTV--KPV----DVGGDEPE--EKVV 319
Query: 300 TLREEA 305
T EA
Sbjct: 320 TSENEA 325
>gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo
sapiens]
Length = 790
Score = 38.9 bits (89), Expect = 0.008
Identities = 52/186 (27%), Positives = 77/186 (41%), Gaps = 35/186 (18%)
Query: 142 EQEQARRDALKQRAEQSISEEPGWEEEE--EELMGISPISPKEAKVPVAKI--------- 190
E+E+A++ K A+ +E E E+ E M IS K A+ P K+
Sbjct: 155 EKEEAKKTEDKSLAKPETDKEQDSEMEKGGREDMDIS----KSAEEPQEKVDLTLDWLTE 210
Query: 191 -STFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVT----------QIANPATA 239
S +G P+ P E VTS +P EV +E +S+S Q
Sbjct: 211 TSEEAKGGAAPEGPNEAE-VTSGKPEQEVPDAEEEKSVSGTDVQEECREKGGQEKQGEVI 269
Query: 240 PEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVE 299
PK++S++ +LE+QG AV+V P + KP+ GG EP +V
Sbjct: 270 VSIEEKPKEVSEEQPVVTLEKQGTAVEVEAESLDPTV--KPV----DVGGDEPE--EKVV 321
Query: 300 TLREEA 305
T EA
Sbjct: 322 TSENEA 327
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 38.5 bits (88), Expect = 0.010
Identities = 36/117 (30%), Positives = 50/117 (42%), Gaps = 8/117 (6%)
Query: 170 EELMGISPISPKEAKVPVAKISTFPEGEP--GPQSPCEENLVTSVEP-PAEVTPSESSES 226
EE + P+ P+E + P EP GP P E++ +T+ P EV S S ES
Sbjct: 1152 EEPPTMPPLPPEEPPMT----PPLPPEEPPEGPALPTEQSALTAENTWPTEVPSSPSEES 1207
Query: 227 ISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTP 283
+S + + E +P D S + S+ AV V E P P S LTP
Sbjct: 1208 VSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPEPE-SSITLTP 1263
Score = 30.0 bits (66), Expect = 3.5
Identities = 24/88 (27%), Positives = 33/88 (37%), Gaps = 6/88 (6%)
Query: 160 SEEPGWEEEEEELMGISPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVT 219
+E P EE P+S E P A + + P E VT EPP E
Sbjct: 1197 TEVPSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPE-- 1254
Query: 220 PSESSESISLVTQIANPATAPEARVLPK 247
ES +T + + A E V+P+
Sbjct: 1255 ----PESSITLTPVESAVVAEEHEVVPE 1278
Score = 29.3 bits (64), Expect = 6.0
Identities = 31/119 (26%), Positives = 42/119 (35%), Gaps = 17/119 (14%)
Query: 177 PISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTP----SESSESISLVTQ 232
P P + PV ++S G P P +EPP EV ++ + LVT
Sbjct: 436 PELPGPSVTPVPQLSQELPGLPAPSM--------GLEPPQEVPEPPVMAQELPGLPLVTA 487
Query: 233 IANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPE 291
P V + Q + LE+ VG T P H + T G G PE
Sbjct: 488 AVELPEQPAVTVAMELTEQPVTTTELEQP-----VGMTTVEHPGHPEVTTATGLLGQPE 541
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 38.5 bits (88), Expect = 0.010
Identities = 36/117 (30%), Positives = 50/117 (42%), Gaps = 8/117 (6%)
Query: 170 EELMGISPISPKEAKVPVAKISTFPEGEP--GPQSPCEENLVTSVEP-PAEVTPSESSES 226
EE + P+ P+E + P EP GP P E++ +T+ P EV S S ES
Sbjct: 1152 EEPPTMPPLPPEEPPMT----PPLPPEEPPEGPALPTEQSALTAENTWPTEVPSSPSEES 1207
Query: 227 ISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTP 283
+S + + E +P D S + S+ AV V E P P S LTP
Sbjct: 1208 VSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPEPE-SSITLTP 1263
Score = 30.0 bits (66), Expect = 3.5
Identities = 24/88 (27%), Positives = 33/88 (37%), Gaps = 6/88 (6%)
Query: 160 SEEPGWEEEEEELMGISPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVT 219
+E P EE P+S E P A + + P E VT EPP E
Sbjct: 1197 TEVPSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPE-- 1254
Query: 220 PSESSESISLVTQIANPATAPEARVLPK 247
ES +T + + A E V+P+
Sbjct: 1255 ----PESSITLTPVESAVVAEEHEVVPE 1278
Score = 29.3 bits (64), Expect = 6.0
Identities = 31/119 (26%), Positives = 42/119 (35%), Gaps = 17/119 (14%)
Query: 177 PISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTP----SESSESISLVTQ 232
P P + PV ++S G P P +EPP EV ++ + LVT
Sbjct: 436 PELPGPSVTPVPQLSQELPGLPAPSM--------GLEPPQEVPEPPVMAQELPGLPLVTA 487
Query: 233 IANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPE 291
P V + Q + LE+ VG T P H + T G G PE
Sbjct: 488 AVELPEQPAVTVAMELTEQPVTTTELEQP-----VGMTTVEHPGHPEVTTATGLLGQPE 541
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 38.5 bits (88), Expect = 0.010
Identities = 35/111 (31%), Positives = 46/111 (41%), Gaps = 23/111 (20%)
Query: 187 VAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEARVLP 246
+A+ +P G+ P SP E V+ PA P ES+ +VT P EAR LP
Sbjct: 2303 LAETEHWPPGQESPTSPTETRPVSP--GPASGVPHHG-ESVQMVT--TTPIPQMEARTLP 2357
Query: 247 KDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPAR 297
++ AV V PP P TPAG + P P PP +
Sbjct: 2358 PGMA-------------AVTV-----VPPHPVTPATPAGQSVAPGPFPPVQ 2390
>gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo
sapiens]
Length = 729
Score = 38.1 bits (87), Expect = 0.013
Identities = 54/223 (24%), Positives = 84/223 (37%), Gaps = 33/223 (14%)
Query: 167 EEEEELM----GISPISPKEAKVPVAKISTFPEGEP----------GPQSPCEENLVT-- 210
EEE E+ G +P +P++ P K S+ P +P P P ++ T
Sbjct: 472 EEEAEVAAPTKGPAP-APQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGP 530
Query: 211 ----SVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVD 266
S PPAE+ P + Q ++ + PE + + LS + + E +G D
Sbjct: 531 EKRSSTRPPAEMEPGKGE-------QASSSESDPEGPIAAQMLSFVMDDPDFESEGS--D 581
Query: 267 VGETGPSPPIHSKPLTPAGHTGGP-EPRPPARVETLREEAPTDLRVFELN-SDSGKSTPS 324
P+ P GP EP PP ++ D +F L ++G S
Sbjct: 582 TQRRADDFPVRDDPSDVTDEDEGPAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESS 641
Query: 325 NNGKKGSSTDISEDWEKDFDLDMTEEEVQMALSKVDASGELED 367
GK+G T E +K EE+ SK S + E+
Sbjct: 642 EEGKEG-KTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEE 683
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 38.1 bits (87), Expect = 0.013
Identities = 48/193 (24%), Positives = 72/193 (37%), Gaps = 15/193 (7%)
Query: 176 SPISPKEAK--VPVAKISTFPEGEPGPQSPCEENLVTSVEP----PAEVTPSESSESISL 229
+P +PKE P T P+ EP P +P E T+ +P P E P+ E+
Sbjct: 427 APTTPKEPAPTTPKKPAPTTPK-EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT 485
Query: 230 VTQIANPAT----APEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAG 285
+ P T AP P + + L + E+ E P+ P + P TP
Sbjct: 486 TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK- 544
Query: 286 HTGGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDL 345
P+ PA T +E APT + E + K T K+ + T + K+
Sbjct: 545 EPAPTTPKEPAPT-TPKEPAPTTPK--ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 601
Query: 346 DMTEEEVQMALSK 358
T+E K
Sbjct: 602 TTTKEPTSTTCDK 614
Score = 35.0 bits (79), Expect = 0.11
Identities = 34/132 (25%), Positives = 48/132 (36%), Gaps = 20/132 (15%)
Query: 176 SPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIAN 235
+P +PKE K + EP P T+ + PA TP E + + T+
Sbjct: 240 APTTPKEPAPTTTKSAPTTPKEPAP---------TTTKEPAPTTPKEPAPT---TTKEPA 287
Query: 236 PATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPP 295
P T A PK+ + + + T P P + P PA T P P P
Sbjct: 288 PTTTKSAPTTPKEPAPTTPKKPAPT--TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 345
Query: 296 ARVETLREEAPT 307
+E APT
Sbjct: 346 ------KEPAPT 351
Score = 33.5 bits (75), Expect = 0.32
Identities = 34/140 (24%), Positives = 52/140 (37%), Gaps = 12/140 (8%)
Query: 176 SPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEP----PAEVTPSESSESISLVT 231
+P +PKE + + EP P +P + T EP P E P+ + E
Sbjct: 326 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 385
Query: 232 QIANPATAPEARVLPKDLSQKLLEA--SLEEQGLAVDVGETGPSPPIHSKPLTP--AGHT 287
+ P T A K+ + ++ + ++ E P+ P P TP T
Sbjct: 386 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 445
Query: 288 GGPEPRPPARVETLREEAPT 307
EP P T +E APT
Sbjct: 446 TPKEPAP----TTPKEPAPT 461
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 38.1 bits (87), Expect = 0.013
Identities = 48/193 (24%), Positives = 72/193 (37%), Gaps = 15/193 (7%)
Query: 176 SPISPKEAK--VPVAKISTFPEGEPGPQSPCEENLVTSVEP----PAEVTPSESSESISL 229
+P +PKE P T P+ EP P +P E T+ +P P E P+ E+
Sbjct: 468 APTTPKEPAPTTPKKPAPTTPK-EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT 526
Query: 230 VTQIANPAT----APEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAG 285
+ P T AP P + + L + E+ E P+ P + P TP
Sbjct: 527 TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK- 585
Query: 286 HTGGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDL 345
P+ PA T +E APT + E + K T K+ + T + K+
Sbjct: 586 EPAPTTPKEPAPT-TPKEPAPTTPK--ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 642
Query: 346 DMTEEEVQMALSK 358
T+E K
Sbjct: 643 TTTKEPTSTTCDK 655
Score = 35.0 bits (79), Expect = 0.11
Identities = 34/132 (25%), Positives = 48/132 (36%), Gaps = 20/132 (15%)
Query: 176 SPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIAN 235
+P +PKE K + EP P T+ + PA TP E + + T+
Sbjct: 281 APTTPKEPAPTTTKSAPTTPKEPAP---------TTTKEPAPTTPKEPAPT---TTKEPA 328
Query: 236 PATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPP 295
P T A PK+ + + + T P P + P PA T P P P
Sbjct: 329 PTTTKSAPTTPKEPAPTTPKKPAPT--TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 386
Query: 296 ARVETLREEAPT 307
+E APT
Sbjct: 387 ------KEPAPT 392
Score = 33.5 bits (75), Expect = 0.32
Identities = 34/140 (24%), Positives = 52/140 (37%), Gaps = 12/140 (8%)
Query: 176 SPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEP----PAEVTPSESSESISLVT 231
+P +PKE + + EP P +P + T EP P E P+ + E
Sbjct: 367 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 426
Query: 232 QIANPATAPEARVLPKDLSQKLLEA--SLEEQGLAVDVGETGPSPPIHSKPLTP--AGHT 287
+ P T A K+ + ++ + ++ E P+ P P TP T
Sbjct: 427 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 486
Query: 288 GGPEPRPPARVETLREEAPT 307
EP P T +E APT
Sbjct: 487 TPKEPAP----TTPKEPAPT 502
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 38.1 bits (87), Expect = 0.013
Identities = 48/193 (24%), Positives = 72/193 (37%), Gaps = 15/193 (7%)
Query: 176 SPISPKEAK--VPVAKISTFPEGEPGPQSPCEENLVTSVEP----PAEVTPSESSESISL 229
+P +PKE P T P+ EP P +P E T+ +P P E P+ E+
Sbjct: 520 APTTPKEPAPTTPKKPAPTTPK-EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT 578
Query: 230 VTQIANPAT----APEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAG 285
+ P T AP P + + L + E+ E P+ P + P TP
Sbjct: 579 TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK- 637
Query: 286 HTGGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDL 345
P+ PA T +E APT + E + K T K+ + T + K+
Sbjct: 638 EPAPTTPKEPAPT-TPKEPAPTTPK--ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 694
Query: 346 DMTEEEVQMALSK 358
T+E K
Sbjct: 695 TTTKEPTSTTCDK 707
Score = 35.0 bits (79), Expect = 0.11
Identities = 34/132 (25%), Positives = 48/132 (36%), Gaps = 20/132 (15%)
Query: 176 SPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIAN 235
+P +PKE K + EP P T+ + PA TP E + + T+
Sbjct: 333 APTTPKEPAPTTTKSAPTTPKEPAP---------TTTKEPAPTTPKEPAPT---TTKEPA 380
Query: 236 PATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPP 295
P T A PK+ + + + T P P + P PA T P P P
Sbjct: 381 PTTTKSAPTTPKEPAPTTPKKPAPT--TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 438
Query: 296 ARVETLREEAPT 307
+E APT
Sbjct: 439 ------KEPAPT 444
Score = 33.5 bits (75), Expect = 0.32
Identities = 34/140 (24%), Positives = 52/140 (37%), Gaps = 12/140 (8%)
Query: 176 SPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEP----PAEVTPSESSESISLVT 231
+P +PKE + + EP P +P + T EP P E P+ + E
Sbjct: 419 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 478
Query: 232 QIANPATAPEARVLPKDLSQKLLEA--SLEEQGLAVDVGETGPSPPIHSKPLTP--AGHT 287
+ P T A K+ + ++ + ++ E P+ P P TP T
Sbjct: 479 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 538
Query: 288 GGPEPRPPARVETLREEAPT 307
EP P T +E APT
Sbjct: 539 TPKEPAP----TTPKEPAPT 554
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 38.1 bits (87), Expect = 0.013
Identities = 41/172 (23%), Positives = 71/172 (41%), Gaps = 26/172 (15%)
Query: 193 FPEGEPGPQSP---------CEENLVTSVEPPAEVTPSESSESISLVTQIANPATAPEAR 243
FP G P +P ++ +V PP ++TP+ ++ ++Q N T R
Sbjct: 986 FPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMRPMNQMSQTLNGQTMGPLR 1045
Query: 244 VL---PKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARVET 300
L P LS ++L +L + G ++ TG + P LTP+ P P +R
Sbjct: 1046 GLNLRPNQLSTQIL-PNLNQSGTGLNQSRTGINQP---PSLTPSNF---PSPNQSSRAFQ 1098
Query: 301 LREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDI------SEDWEKDFDLD 346
+ + +DL L+ + P+ N + ++DW KD +LD
Sbjct: 1099 GTDHS-SDLAFDFLSQQNDNMGPALNSDADFIDSLLKTEPGNDDWMKDINLD 1149
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 38.1 bits (87), Expect = 0.013
Identities = 48/193 (24%), Positives = 72/193 (37%), Gaps = 15/193 (7%)
Query: 176 SPISPKEAK--VPVAKISTFPEGEPGPQSPCEENLVTSVEP----PAEVTPSESSESISL 229
+P +PKE P T P+ EP P +P E T+ +P P E P+ E+
Sbjct: 561 APTTPKEPAPTTPKKPAPTTPK-EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT 619
Query: 230 VTQIANPAT----APEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAG 285
+ P T AP P + + L + E+ E P+ P + P TP
Sbjct: 620 TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPK- 678
Query: 286 HTGGPEPRPPARVETLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISEDWEKDFDL 345
P+ PA T +E APT + E + K T K+ + T + K+
Sbjct: 679 EPAPTTPKEPAPT-TPKEPAPTTPK--ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 735
Query: 346 DMTEEEVQMALSK 358
T+E K
Sbjct: 736 TTTKEPTSTTCDK 748
Score = 35.0 bits (79), Expect = 0.11
Identities = 34/132 (25%), Positives = 48/132 (36%), Gaps = 20/132 (15%)
Query: 176 SPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIAN 235
+P +PKE K + EP P T+ + PA TP E + + T+
Sbjct: 374 APTTPKEPAPTTTKSAPTTPKEPAP---------TTTKEPAPTTPKEPAPT---TTKEPA 421
Query: 236 PATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPP 295
P T A PK+ + + + T P P + P PA T P P P
Sbjct: 422 PTTTKSAPTTPKEPAPTTPKKPAPT--TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 479
Query: 296 ARVETLREEAPT 307
+E APT
Sbjct: 480 ------KEPAPT 485
Score = 33.5 bits (75), Expect = 0.32
Identities = 34/140 (24%), Positives = 52/140 (37%), Gaps = 12/140 (8%)
Query: 176 SPISPKEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEP----PAEVTPSESSESISLVT 231
+P +PKE + + EP P +P + T EP P E P+ + E
Sbjct: 460 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 519
Query: 232 QIANPATAPEARVLPKDLSQKLLEA--SLEEQGLAVDVGETGPSPPIHSKPLTP--AGHT 287
+ P T A K+ + ++ + ++ E P+ P P TP T
Sbjct: 520 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 579
Query: 288 GGPEPRPPARVETLREEAPT 307
EP P T +E APT
Sbjct: 580 TPKEPAP----TTPKEPAPT 595
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 37.7 bits (86), Expect = 0.017
Identities = 35/131 (26%), Positives = 48/131 (36%), Gaps = 12/131 (9%)
Query: 176 SPISPKEAKVPVAKIST-----------FPEGEPGPQSPCEENLVTSVEPPAE-VTPSES 223
SP+SP E P + T P E P SP E L TS P A ++P
Sbjct: 518 SPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPE 577
Query: 224 SESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTP 283
+S + + + PEA L + L EE L+ + SPP P++P
Sbjct: 578 ESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSP 637
Query: 284 AGHTGGPEPRP 294
P P
Sbjct: 638 PPEESPMSPPP 648
Score = 37.0 bits (84), Expect = 0.029
Identities = 37/143 (25%), Positives = 57/143 (39%), Gaps = 12/143 (8%)
Query: 176 SPISPKEAKVPVA---KISTFPEGEPGPQSPCEEN-----LVTSVEPPAEVTPSE---SS 224
SP+SP + P++ + S F E P SP EE+ L T + PP E +P
Sbjct: 492 SPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEE 551
Query: 225 ESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPA 284
+S + + PEA L + + EE ++ + PP PL+P
Sbjct: 552 SPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPP 611
Query: 285 GHTGGPEPRPPA-RVETLREEAP 306
P P A R+ E++P
Sbjct: 612 PEESPLSPPPEASRLSPPPEDSP 634
Score = 33.5 bits (75), Expect = 0.32
Identities = 29/121 (23%), Positives = 48/121 (39%), Gaps = 7/121 (5%)
Query: 178 ISPKEAKVPVAKISTFPEGEPGPQSPC------EENLVTSVEPPAEVTPSESSESISLVT 231
+SP+ + ++ + P P P+ PC E +L E P ++P +S T
Sbjct: 752 LSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGP-HLSPQPEELHLSPQT 810
Query: 232 QIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPE 291
+ + + PE L + L EE L+ E+ SP + PL+P E
Sbjct: 811 EEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEE 870
Query: 292 P 292
P
Sbjct: 871 P 871
Score = 32.3 bits (72), Expect = 0.71
Identities = 30/109 (27%), Positives = 46/109 (42%), Gaps = 15/109 (13%)
Query: 197 EPGPQSPCEENLV-------TSVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKDL 249
EP ++P E + + + PP E +P+ S +++ P A LP+ L
Sbjct: 427 EPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEAS---RLSPPPEELPASPLPEAL 483
Query: 250 SQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHT--GGPEPRPPA 296
L LEE L+ E+ SPP S P +P + PE PP+
Sbjct: 484 H---LSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPS 529
Score = 31.2 bits (69), Expect = 1.6
Identities = 37/147 (25%), Positives = 54/147 (36%), Gaps = 15/147 (10%)
Query: 176 SPISPKEAKVPVAK----ISTFPEGEPGPQSPCEENLVTSVEPPAE-VTPSESSESISLV 230
SP+SP ++P + P E P SP E S P A + P +S
Sbjct: 552 SPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPP 611
Query: 231 TQIANPATAPEARVLPKDLSQKLLEASLEEQGLAV--DVGETGP-------SPPIHSKPL 281
+ + + PEA L + EE ++ +V P SPP PL
Sbjct: 612 PEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPL 671
Query: 282 TPAGHTGGPEPRPPA-RVETLREEAPT 307
+P P P A R+ E++PT
Sbjct: 672 SPPPEESPTSPPPEASRLSPPPEDSPT 698
>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
Length = 1303
Score = 37.7 bits (86), Expect = 0.017
Identities = 55/249 (22%), Positives = 85/249 (34%), Gaps = 66/249 (26%)
Query: 141 LEQEQARRDALKQRAEQSI----------------SEEPGWEEEEEELMGISPISPKEAK 184
L+Q+Q ++ KQ+ +Q + +++P W E EE ++ K+
Sbjct: 479 LQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMN----KQQN 534
Query: 185 VPVAKIST--------FPEGEPGPQSPCEENLVTSVEPPAE--VTPSESSESISLVTQIA 234
P+AK P+ PGP P + PP + V P E + ++
Sbjct: 535 SPLAKSKPGSTGPEPPIPQASPGPPGPLSQT------PPMQRPVEPQEGPHKSLVAHRVP 588
Query: 235 -NPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTG----- 288
P AP R SQ L + + LA P P I + TP+
Sbjct: 589 LKPYAAPVPR------SQSLQDQPT--RNLAAFPASHDPDPAIPAPTATPSARGAVIRQN 640
Query: 289 --------GPEPRPPARVETLREEAP-----TDLRVFELNSDSGKSTPSNNGKKGSSTDI 335
GP P PPA V E P T LN+ + + S+ D+
Sbjct: 641 SDPTSEGPGPSPNPPAWVRPDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRASNPDL 700
Query: 336 SED---WEK 341
WE+
Sbjct: 701 RRSDPGWER 709
>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
Length = 1295
Score = 37.7 bits (86), Expect = 0.017
Identities = 55/249 (22%), Positives = 85/249 (34%), Gaps = 66/249 (26%)
Query: 141 LEQEQARRDALKQRAEQSI----------------SEEPGWEEEEEELMGISPISPKEAK 184
L+Q+Q ++ KQ+ +Q + +++P W E EE ++ K+
Sbjct: 479 LQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMN----KQQN 534
Query: 185 VPVAKIST--------FPEGEPGPQSPCEENLVTSVEPPAE--VTPSESSESISLVTQIA 234
P+AK P+ PGP P + PP + V P E + ++
Sbjct: 535 SPLAKSKPGSTGPEPPIPQASPGPPGPLSQT------PPMQRPVEPQEGPHKSLVAHRVP 588
Query: 235 -NPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTG----- 288
P AP R SQ L + + LA P P I + TP+
Sbjct: 589 LKPYAAPVPR------SQSLQDQPT--RNLAAFPASHDPDPAIPAPTATPSARGAVIRQN 640
Query: 289 --------GPEPRPPARVETLREEAP-----TDLRVFELNSDSGKSTPSNNGKKGSSTDI 335
GP P PPA V E P T LN+ + + S+ D+
Sbjct: 641 SDPTSEGPGPSPNPPAWVRPDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRASNPDL 700
Query: 336 SED---WEK 341
WE+
Sbjct: 701 RRSDPGWER 709
>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
Length = 1332
Score = 37.4 bits (85), Expect = 0.022
Identities = 48/206 (23%), Positives = 72/206 (34%), Gaps = 58/206 (28%)
Query: 141 LEQEQARRDALKQRAEQSI----------------SEEPGWEEEEEELMGISPISPKEAK 184
L+Q+Q ++ KQ+ +Q + +++P W E EE ++ K+
Sbjct: 479 LQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMN----KQQN 534
Query: 185 VPVAKIST--------FPEGEPGPQSPCEENLVTSVEPPAE--VTPSESSESISLVTQIA 234
P+AK P+ PGP P + PP + V P E + ++
Sbjct: 535 SPLAKSKPGSTGPEPPIPQASPGPPGPLSQT------PPMQRPVEPQEGPHKSLVAHRVP 588
Query: 235 -NPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTG----- 288
P AP R SQ L + + LA P P I + TP+
Sbjct: 589 LKPYAAPVPR------SQSLQDQPT--RNLAAFPASHDPDPAIPAPTATPSARGAVIRQN 640
Query: 289 --------GPEPRPPARVETLREEAP 306
GP P PPA V E P
Sbjct: 641 SDPTSEGPGPSPNPPAWVRPDNEAPP 666
>gi|40807452 peroxisome proliferator-activated receptor gamma,
coactivator-related 1 [Homo sapiens]
Length = 1664
Score = 37.0 bits (84), Expect = 0.029
Identities = 32/120 (26%), Positives = 44/120 (36%), Gaps = 10/120 (8%)
Query: 211 SVEPPAEVTPSESSESISLVTQIANPATAPEARVLPKDLSQKLLEASLEEQGLAVDVGET 270
S++PP + P SL + AT EAR P LS E Q + E
Sbjct: 715 SLDPPKTIIPEVKEVVDSLKIESGTSATTHEARPRPLSLS----EYRRRRQQRQAETEER 770
Query: 271 GPSPPIHSKPLTPAGHTGGPE------PRPPARVETLREEAPTDLRVFELNSDSGKSTPS 324
P PP P P TG + P PA+ L+ T L + + ++PS
Sbjct: 771 SPQPPTGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASPS 830
>gi|154800453 tastin isoform 1 [Homo sapiens]
Length = 778
Score = 37.0 bits (84), Expect = 0.029
Identities = 47/144 (32%), Positives = 59/144 (40%), Gaps = 24/144 (16%)
Query: 170 EELMGISPISPKEAKVPVAKISTFPE-GEPGPQSPCEENLVTSVEPPAEVTPSESS---- 224
EE P P E P A + PE EP Q E V PPAE P ES
Sbjct: 507 EECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLE---VPEPYPPAEPRPLESCCRSE 563
Query: 225 ---ESISLVTQIANPATAPEARVLPKD----LSQKLLEASLEEQGLAVDVGETGPSPPIH 277
S Q+ P P A P + + ++ E+S +EQ ++V E P PP
Sbjct: 564 PEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQ---LEVPE--PCPPAE 618
Query: 278 SKPLTPA--GHTGGPEPRPPARVE 299
PL P+ G +G P P P RVE
Sbjct: 619 PGPLQPSTQGQSGPPGPCP--RVE 640
>gi|4502483 Ras association (RalGDS/AF-6) domain family (N-terminal)
member 7 isoform 1 [Homo sapiens]
Length = 373
Score = 36.6 bits (83), Expect = 0.038
Identities = 48/186 (25%), Positives = 74/186 (39%), Gaps = 35/186 (18%)
Query: 125 VSHSEFWHRYFYKVHQLEQE-QARRDALKQRAEQSISEEPGWEEEEEELMGISPISPKEA 183
+ H FW + + E+E QAR AL + + + + L EA
Sbjct: 169 LGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARAL---------EA 219
Query: 184 KVPVAKISTFPEGEPGPQSPC-------EENLVTSVEPPAEVTPSESSESISL-VTQIAN 235
++ +A + PGP SP ++L AEV S + S +L + A
Sbjct: 220 ELQLAAEA------PGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERAL 273
Query: 236 PATAPEARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPP 295
A A E L ++L Q L+ +++ G A+ P PP + G G P PP
Sbjct: 274 QAQAQELEELNRELRQCNLQQFIQQTGAAL------PPPPRPDR-----GPPGTQGPLPP 322
Query: 296 ARVETL 301
AR E+L
Sbjct: 323 AREESL 328
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.126 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,235,086
Number of Sequences: 37866
Number of extensions: 949615
Number of successful extensions: 5834
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 387
Number of HSP's that attempted gapping in prelim test: 5276
Number of HSP's gapped (non-prelim): 944
length of query: 374
length of database: 18,247,518
effective HSP length: 104
effective length of query: 270
effective length of database: 14,309,454
effective search space: 3863552580
effective search space used: 3863552580
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.