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Search of human proteins with 221136781
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221136781 S1 RNA binding domain 1 [Homo sapiens]
(995 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221136781 S1 RNA binding domain 1 [Homo sapiens] 1967 0.0
gi|27597090 suppressor of Ty 6 homolog [Homo sapiens] 72 3e-12
gi|56118310 nuclear casein kinase and cyclin-dependent kinase su... 45 4e-04
gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens] 43 0.002
gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens] 42 0.003
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 42 0.003
gi|41055989 M-phase phosphoprotein 8 [Homo sapiens] 41 0.005
gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens] 40 0.011
gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens] 40 0.014
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 39 0.019
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 39 0.019
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 39 0.032
gi|104526627 triadin [Homo sapiens] 38 0.054
gi|221219020 NYD-SP11 protein [Homo sapiens] 37 0.071
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 37 0.071
gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1 [... 37 0.092
gi|157738613 coiled-coil alpha-helical rod protein 1 isoform 2 [... 37 0.092
gi|157738611 coiled-coil alpha-helical rod protein 1 isoform 3 [... 37 0.092
gi|30061491 erythrocyte membrane protein band 4.1-like 1 isoform... 37 0.12
gi|30061489 erythrocyte membrane protein band 4.1-like 1 isoform... 37 0.12
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 37 0.12
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 37 0.12
gi|61743963 chromobox homolog 2 isoform 1 [Homo sapiens] 36 0.16
gi|58530840 desmoplakin isoform I [Homo sapiens] 36 0.21
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 36 0.21
gi|154354974 phosphatase and actin regulator 2 isoform 3 [Homo s... 36 0.21
gi|154354968 phosphatase and actin regulator 2 isoform 1 [Homo s... 36 0.21
gi|6453818 kinesin family member 22 [Homo sapiens] 36 0.21
gi|225543215 antigen identified by monoclonal antibody Ki-67 iso... 35 0.27
gi|103472005 antigen identified by monoclonal antibody Ki-67 iso... 35 0.27
>gi|221136781 S1 RNA binding domain 1 [Homo sapiens]
Length = 995
Score = 1967 bits (5095), Expect = 0.0
Identities = 995/995 (100%), Positives = 995/995 (100%)
Query: 1 MSSLPRRAKVQVQDVVLKDEFSSFSELSSASEEDDKEDSAWEPQKKVPRSRKQPPPKESK 60
MSSLPRRAKVQVQDVVLKDEFSSFSELSSASEEDDKEDSAWEPQKKVPRSRKQPPPKESK
Sbjct: 1 MSSLPRRAKVQVQDVVLKDEFSSFSELSSASEEDDKEDSAWEPQKKVPRSRKQPPPKESK 60
Query: 61 PKRMPRVKKNAPQISDGSEVVVVKEELNSSVAIADTALEDRKNKLDTVQTLKTAKTKQKC 120
PKRMPRVKKNAPQISDGSEVVVVKEELNSSVAIADTALEDRKNKLDTVQTLKTAKTKQKC
Sbjct: 61 PKRMPRVKKNAPQISDGSEVVVVKEELNSSVAIADTALEDRKNKLDTVQTLKTAKTKQKC 120
Query: 121 AAQPHTVRRTKKLKVEEETSKASNLEGESNSSETPSTSTVWGGTCKKEENDDDFTFGQSA 180
AAQPHTVRRTKKLKVEEETSKASNLEGESNSSETPSTSTVWGGTCKKEENDDDFTFGQSA
Sbjct: 121 AAQPHTVRRTKKLKVEEETSKASNLEGESNSSETPSTSTVWGGTCKKEENDDDFTFGQSA 180
Query: 181 LKKIKTETYPQGQPVKFPANANSTKEEVEMNWDMVQVLSERTNIEPWVCANIIRLFNDDN 240
LKKIKTETYPQGQPVKFPANANSTKEEVEMNWDMVQVLSERTNIEPWVCANIIRLFNDDN
Sbjct: 181 LKKIKTETYPQGQPVKFPANANSTKEEVEMNWDMVQVLSERTNIEPWVCANIIRLFNDDN 240
Query: 241 TIPFIIRYRKELINNLDADSLREVQQTLEELRAVAKKVHSTIQKIKKEGKMSECLLKAML 300
TIPFIIRYRKELINNLDADSLREVQQTLEELRAVAKKVHSTIQKIKKEGKMSECLLKAML
Sbjct: 241 TIPFIIRYRKELINNLDADSLREVQQTLEELRAVAKKVHSTIQKIKKEGKMSECLLKAML 300
Query: 301 NCKTFEELEHVSAPYKTGSKGTKAQRARQLGLEGAARALLEKPGELSLLSYIRPDVKGLS 360
NCKTFEELEHVSAPYKTGSKGTKAQRARQLGLEGAARALLEKPGELSLLSYIRPDVKGLS
Sbjct: 301 NCKTFEELEHVSAPYKTGSKGTKAQRARQLGLEGAARALLEKPGELSLLSYIRPDVKGLS 360
Query: 361 TLQDIEIGVQHILADMIAKDKDTLDFIRNLCQKRHVCIQSSLAKVSSKKVNEKDVDKFLL 420
TLQDIEIGVQHILADMIAKDKDTLDFIRNLCQKRHVCIQSSLAKVSSKKVNEKDVDKFLL
Sbjct: 361 TLQDIEIGVQHILADMIAKDKDTLDFIRNLCQKRHVCIQSSLAKVSSKKVNEKDVDKFLL 420
Query: 421 YQHFSCNIRNIHHHQILAINRGENLKVLTVKVNISDGVKDEFCRWCIQNRWRPRSFARPE 480
YQHFSCNIRNIHHHQILAINRGENLKVLTVKVNISDGVKDEFCRWCIQNRWRPRSFARPE
Sbjct: 421 YQHFSCNIRNIHHHQILAINRGENLKVLTVKVNISDGVKDEFCRWCIQNRWRPRSFARPE 480
Query: 481 LMKILYNSLNDSFKRLIYPLLCREFRAKLTSDAEKESVMMFGRNLRQLLLTSPVPGRTLM 540
LMKILYNSLNDSFKRLIYPLLCREFRAKLTSDAEKESVMMFGRNLRQLLLTSPVPGRTLM
Sbjct: 481 LMKILYNSLNDSFKRLIYPLLCREFRAKLTSDAEKESVMMFGRNLRQLLLTSPVPGRTLM 540
Query: 541 GVDPGYKHGCKLAIISPTSQILHTDVVYLHCGQGFREAEKIKTLLLNFNCSTVVIGNGTA 600
GVDPGYKHGCKLAIISPTSQILHTDVVYLHCGQGFREAEKIKTLLLNFNCSTVVIGNGTA
Sbjct: 541 GVDPGYKHGCKLAIISPTSQILHTDVVYLHCGQGFREAEKIKTLLLNFNCSTVVIGNGTA 600
Query: 601 CRETEAYFADLIMKNYFAPLDVVYCIVSEAGASIYSVSPEANKEMPGLDPNLRSAVSIAR 660
CRETEAYFADLIMKNYFAPLDVVYCIVSEAGASIYSVSPEANKEMPGLDPNLRSAVSIAR
Sbjct: 601 CRETEAYFADLIMKNYFAPLDVVYCIVSEAGASIYSVSPEANKEMPGLDPNLRSAVSIAR 660
Query: 661 RVQDPLAELVKIEPKHIGVGMYQHDVSQTLLKATLDSVVEECVSFVGVDINICSEVLLRH 720
RVQDPLAELVKIEPKHIGVGMYQHDVSQTLLKATLDSVVEECVSFVGVDINICSEVLLRH
Sbjct: 661 RVQDPLAELVKIEPKHIGVGMYQHDVSQTLLKATLDSVVEECVSFVGVDINICSEVLLRH 720
Query: 721 IAGLNANRAKNIIEWREKNGPFINREQLKKVKGLGPKSFQQCAGFIRINQDYIRTFCSQQ 780
IAGLNANRAKNIIEWREKNGPFINREQLKKVKGLGPKSFQQCAGFIRINQDYIRTFCSQQ
Sbjct: 721 IAGLNANRAKNIIEWREKNGPFINREQLKKVKGLGPKSFQQCAGFIRINQDYIRTFCSQQ 780
Query: 781 TETSGQIQGVAVTSSADVEVTNEKQGKKKSKTAVNVLLKPNPLDQTCIHPESYDIAMRFL 840
TETSGQIQGVAVTSSADVEVTNEKQGKKKSKTAVNVLLKPNPLDQTCIHPESYDIAMRFL
Sbjct: 781 TETSGQIQGVAVTSSADVEVTNEKQGKKKSKTAVNVLLKPNPLDQTCIHPESYDIAMRFL 840
Query: 841 SSIGGTLYEVGKPEMQQKINSFLEKEGMEKIAERLQTTVHTLQVIIDGLSQPESFDFRTD 900
SSIGGTLYEVGKPEMQQKINSFLEKEGMEKIAERLQTTVHTLQVIIDGLSQPESFDFRTD
Sbjct: 841 SSIGGTLYEVGKPEMQQKINSFLEKEGMEKIAERLQTTVHTLQVIIDGLSQPESFDFRTD 900
Query: 901 FDKPDFKRSIVCLEDLQIGTVLTGKVENATLFGIFVDIGVGKSGLIPIRNVTEAKLSKTK 960
FDKPDFKRSIVCLEDLQIGTVLTGKVENATLFGIFVDIGVGKSGLIPIRNVTEAKLSKTK
Sbjct: 901 FDKPDFKRSIVCLEDLQIGTVLTGKVENATLFGIFVDIGVGKSGLIPIRNVTEAKLSKTK 960
Query: 961 KRRSLGLGPGERVEVQVLNIDIPRSRITLDLIRVL 995
KRRSLGLGPGERVEVQVLNIDIPRSRITLDLIRVL
Sbjct: 961 KRRSLGLGPGERVEVQVLNIDIPRSRITLDLIRVL 995
>gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]
Length = 1726
Score = 72.0 bits (175), Expect = 3e-12
Identities = 107/475 (22%), Positives = 192/475 (40%), Gaps = 96/475 (20%)
Query: 368 GVQHILADMIAKDKDTLDFIRNLCQKRHVCIQSSLAKVSSKKVNEKDVDKFLLYQHFSC- 426
G ++++A IA++ +R Q+R + ++ K KDVD+ F
Sbjct: 587 GARYMVALQIAREPLVRQVLRQTFQER------AKLNITPTKKGRKDVDEAHYAYSFKYL 640
Query: 427 ---NIRNIHHHQILAINRGENLKVLTVKVNIS-DGV------------------KDEFCR 464
++ + Q L I E+ +LT ++I GV +DEF
Sbjct: 641 KNKPVKELRDDQFLKICLAEDEGLLTTDISIDLKGVEGYGNDQTYFEEIKQFYYRDEFSH 700
Query: 465 WCIQNRWRPRSFARPELMKILYNSLNDSFKRLIYPLLCREFRAKLTSDAEKESVMMFGRN 524
+Q R R+ A + + ++ +Y + +E + KL ++A++ + R
Sbjct: 701 Q-VQEWNRQRTMA-----------IERALQQFLYVQMAKELKNKLLAEAKEYVIKACSRK 748
Query: 525 LRQLLLTSPV-PGRTLMG----VDPGYKHGCKLAIISPTSQILHTDVVYLHCGQG----- 574
L L +P P + + +D G ++ I+ +S H L G+G
Sbjct: 749 LYNWLRVAPYRPDQQVEEDDDFMDENQGKGIRVLGIAFSSARDHPVFCALVNGEGEVTDF 808
Query: 575 ------------FREAEK---------IKTLLLNFNCSTVVIGNGTACRETEAYFADLIM 613
+RE E+ +K LLN V + R+ + D+
Sbjct: 809 LRLPHFTKRRTAWREEEREKKAQDIETLKKFLLNKKPHVVTVAGEN--RDAQMLIEDV-- 864
Query: 614 KNYFAPLD-------VVYCIVSEAGASIYSVSPEANKEMPGLDPNLRSAVSIARRVQDPL 666
K LD + +V A +Y S ++ E P LR AVS+ARR+QDPL
Sbjct: 865 KRIVHELDQGQQLSSIGVELVDNELAILYMNSKKSEAEFRDYPPVLRQAVSLARRIQDPL 924
Query: 667 AELVKIEPKHIGV------GMYQHDVSQTLLKATLDSVVEECVSFVGVDINIC-----SE 715
E ++ + + +H V + LL A + V+ VGVD+N S+
Sbjct: 925 IEFAQVCSSDEDILCLKFHPLQEHVVKEELLNALYCEFINR-VNEVGVDVNRAIAHPYSQ 983
Query: 716 VLLRHIAGLNANRAKNIIE-WREKNGPFINREQLKKVKGLGPKSFQQCAGFIRIN 769
L++++ GL + ++++ ++ N +R QL + +GPK F CAGF++I+
Sbjct: 984 ALIQYVCGLGPRKGTHLLKILKQNNTRLESRTQLVTMCHMGPKVFMNCAGFLKID 1038
>gi|56118310 nuclear casein kinase and cyclin-dependent kinase
substrate 1 [Homo sapiens]
Length = 243
Score = 44.7 bits (104), Expect = 4e-04
Identities = 47/179 (26%), Positives = 81/179 (45%), Gaps = 20/179 (11%)
Query: 20 EFSSFSELSSASEEDDKEDSAWEPQKKVPRSRKQPPPKESKPKRMPRVKKNAPQISDGSE 79
++S F E S ++ED DS P KK+ S P+E+K KR R KN+ + S+ SE
Sbjct: 12 DYSQFQE-SDDADEDYGRDSG-PPTKKIRSS-----PREAKNKR--RSGKNSQEDSEDSE 62
Query: 80 VVVVKEELNSSVAIADTALEDRKNKLDTVQTLKTAKTKQKCAAQPHTVRRTKKLKVEEET 139
VK + + S + D+ ED K V+ + A +K + + + +EE
Sbjct: 63 DKDVKTKKDDSHSAEDS--EDEKEDHKNVRQQRQAASKAASKQREMLMEDVGSEEEQEEE 120
Query: 140 SKASNLEGESNSSETPSTSTVWGGTCKKEENDDDFTFGQSALKKIKTETYPQGQPVKFP 198
+A E +S S E ++++D D+ + KK+ ++ P+ + K P
Sbjct: 121 DEAPFQEKDSGSDE---------DFLMEDDDDSDYGSSKKKNKKMVKKSKPERKEKKMP 170
>gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]
Length = 285
Score = 42.7 bits (99), Expect = 0.002
Identities = 37/180 (20%), Positives = 72/180 (40%), Gaps = 24/180 (13%)
Query: 8 AKVQVQDVVLKDEFSSFSELSSASEEDDKEDSAWEPQKKVPRSRKQPPPKESKPKRMPRV 67
A V+ Q+ +++ + +E E+D+E+ + + P +P P+ P +P
Sbjct: 19 AAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVP-- 76
Query: 68 KKNAPQISDGSEVVV-------VKEELNSSVAIADTALEDRKNK-------LDTVQTLKT 113
P+I DG V ++++LN A+ + E+RK + D ++ +
Sbjct: 77 ----PKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRA 132
Query: 114 AKTKQKCAAQPHTVRRTKKLKVE----EETSKASNLEGESNSSETPSTSTVWGGTCKKEE 169
+ +Q+ R +L E EE E E+ + S +GG +K E
Sbjct: 133 ERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKTE 192
>gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]
Length = 288
Score = 42.0 bits (97), Expect = 0.003
Identities = 36/179 (20%), Positives = 72/179 (40%), Gaps = 24/179 (13%)
Query: 8 AKVQVQDVVLKDEFSSFSELSSASEEDDKEDSAWEPQKKVPRSRKQPPPKESKPKRMPRV 67
A V+ Q+ +++ + +E E+D+E+ + + P +P P+ P +P
Sbjct: 19 AAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVP-- 76
Query: 68 KKNAPQISDGSEVVV-------VKEELNSSVAIADTALEDRKNK-------LDTVQTLKT 113
P+I DG V ++++LN A+ + E+RK + D ++ +
Sbjct: 77 ----PKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRA 132
Query: 114 AKTKQKCAAQPHTVRRTKKLKVE----EETSKASNLEGESNSSETPSTSTVWGGTCKKE 168
+ +Q+ R +L E EE E E+ + S +GG +K+
Sbjct: 133 ERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKQ 191
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 42.0 bits (97), Expect = 0.003
Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 5/142 (3%)
Query: 2 SSLPRRAKVQVQDVVLKDEFSS-FSELSSASEEDDKEDSAWEPQKKVPRSRKQPPPKESK 60
S L AK +++ K+E S E E KE ++K P + K K+SK
Sbjct: 801 SPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSK 860
Query: 61 PKRMPRVKKNAPQISDGSEVVVVKEELNSSVAIADTALEDRKNKLDTVQTLKTAKTKQKC 120
+ P+ + P++ + E V K + S V ED+K K+ T + AK + K
Sbjct: 861 KEEAPKKEAPKPKVEEKKEPAVEKPK-ESKVEAKKEEAEDKK-KVPTPEKEAPAKVEVKE 918
Query: 121 AAQPHTVRRTKKLKVEEETSKA 142
A+P +T+ K E + +KA
Sbjct: 919 DAKPK--EKTEVAKKEPDDAKA 938
Score = 37.0 bits (84), Expect = 0.092
Identities = 34/137 (24%), Positives = 57/137 (41%), Gaps = 10/137 (7%)
Query: 26 ELSSASEEDDKEDSAWEPQKKVPRSRKQPPPK-----ESKPKRMPRVKKNAPQISDGSEV 80
E S+ + K++ A E +KKVP K+ P K ++KPK V K P + E
Sbjct: 883 EKPKESKVEAKKEEA-EDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEP 941
Query: 81 VVVKEELNSSVAIADTALEDRKNKLDTVQTLKTA----KTKQKCAAQPHTVRRTKKLKVE 136
E+ ++ DT E K + +T A KT K ++P + K +
Sbjct: 942 SKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTD 1001
Query: 137 EETSKASNLEGESNSSE 153
++ SK E +++
Sbjct: 1002 QKDSKPPEKATEDKAAK 1018
Score = 36.6 bits (83), Expect = 0.12
Identities = 51/211 (24%), Positives = 76/211 (36%), Gaps = 29/211 (13%)
Query: 17 LKDEFSSFSELSS-------ASEEDDKEDSAWEPQK---KVPRSRKQPPPKESKPKRMPR 66
+K+E S +E+ S EE + A P+K K P K P E+K +
Sbjct: 622 VKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAK 681
Query: 67 VKKNAPQISDGSEVVVVKEELNSSVAIADTALEDRKNKLDTVQTLK-TAKTKQKCAAQPH 125
A S VKEE S E+ K+ +K AKT +K A+
Sbjct: 682 SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEK--AKSP 739
Query: 126 TVRRTKKLKVEEETSKASNLEGESNSSETPSTSTVWGGTCKKEENDDDFTFGQSALKKIK 185
K + + KA L+ +S ++TP+ K+E F + A +K
Sbjct: 740 VKEEAKSPEKAKSPEKAKTLDVKSPEAKTPA---------KEEARSPADKFPEKAKSPVK 790
Query: 186 TET-------YPQGQPVKFPANANSTKEEVE 209
E P + K P KEEV+
Sbjct: 791 EEVKSPEKAKSPLKEDAKAPEKEIPKKEEVK 821
Score = 33.5 bits (75), Expect = 1.0
Identities = 39/169 (23%), Positives = 71/169 (42%), Gaps = 28/169 (16%)
Query: 5 PRRAKVQVQDVVLKDEFSSFSELSSASEEDDKEDSAWEPQKKVPR----SRKQPP---PK 57
P+ KV+ ++E + + + ++ KE++ P+K+ P+ +K+P PK
Sbjct: 830 PQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEA---PKKEAPKPKVEEKKEPAVEKPK 886
Query: 58 ESKP----------KRMPRVKKNAPQISDGSEVVVVKEELNSSVAIADTALEDRKNKLDT 107
ESK K++P +K AP + E KE+ +A +D K K
Sbjct: 887 ESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEK----TEVAKKEPDDAKAK--- 939
Query: 108 VQTLKTAKTKQKCAAQPHTVRRTKKLKVEEETSKASNLEGESNSSETPS 156
+ K A+ K+ + T K E+ ++A E + S+ PS
Sbjct: 940 -EPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPS 987
Score = 31.2 bits (69), Expect = 5.1
Identities = 38/202 (18%), Positives = 74/202 (36%), Gaps = 4/202 (1%)
Query: 9 KVQVQDVVLKDEFSSFSELSSASEEDDKEDSAWEPQKKVPRSRKQPPPKESKPKRMPRVK 68
K + + V+++++ +EE++KE E +++ ++ E + K P +
Sbjct: 449 KSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEE 508
Query: 69 KNAPQISDGSEVVVVKEELNSSVAIADTALEDRKNKLDTVQTLKTAKTKQKCAAQPHTVR 128
+P+ S VKEE S E+ K+ + K ++ A P +
Sbjct: 509 AASPEKEAKSP---VKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAK 565
Query: 129 RTKKLKVEEETSKASNLEGESNSSETPSTSTVWGGTCKKEENDDDFTFGQSALKKIKTET 188
+K + + S + +S + E + K + + + K E
Sbjct: 566 SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEE 625
Query: 189 YPQGQPVKFPANANS-TKEEVE 209
VK P A S TKEE +
Sbjct: 626 AKSPAEVKSPEKAKSPTKEEAK 647
Score = 31.2 bits (69), Expect = 5.1
Identities = 43/203 (21%), Positives = 70/203 (34%), Gaps = 11/203 (5%)
Query: 9 KVQVQDVVLKDEFSSFSELSSASEEDDKEDSAW---EPQKKVPRSRKQPPPKESKPKRMP 65
+ QV + V ++E E EE +E+ A E K P P KE+K
Sbjct: 463 ETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKE 522
Query: 66 RVKKNAPQISDGSEVVVVKEELNSSVAIADTALEDRKNKLDTVQTLKTAKTKQKCAAQ-P 124
K A S E E+ S A E+ K+ + AK+ +K A+ P
Sbjct: 523 EAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPE-------AKSPEKEEAKSP 575
Query: 125 HTVRRTKKLKVEEETSKASNLEGESNSSETPSTSTVWGGTCKKEENDDDFTFGQSALKKI 184
V+ +K K + S E +S + + + + +K
Sbjct: 576 AEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSP 635
Query: 185 KTETYPQGQPVKFPANANSTKEE 207
+ P + K P A S ++E
Sbjct: 636 EKAKSPTKEEAKSPEKAKSPEKE 658
>gi|41055989 M-phase phosphoprotein 8 [Homo sapiens]
Length = 860
Score = 41.2 bits (95), Expect = 0.005
Identities = 44/166 (26%), Positives = 72/166 (43%), Gaps = 16/166 (9%)
Query: 7 RAKVQVQDVVLKDEFSSFSELSSASEE--DDKEDSAWEPQKKVPRSRKQPPPKESKPKRM 64
+AK +D+ + E +S S++ + KED++ + +KK R R++ P + K K+
Sbjct: 114 KAKAVRKDIQRLSLNNDIFEANSDSDQQSETKEDTSPKKKKKKLRQREEKSPDDLKKKKA 173
Query: 65 PRVK---KNAPQISDGSEVVVVKEELNSSVAIADTAL-EDRKNKLDTVQTLKTAK----- 115
K K+ P + E +V ++ A L E +K K D V+ K K
Sbjct: 174 KAGKLKDKSKPDLESSLESLVFDLRTKKRISEAKEELKESKKPKKDEVKETKELKKVKKG 233
Query: 116 ----TKQKCAAQPHTVRRTKKLK-VEEETSKASNLEGESNSSETPS 156
K K P R+TKK K VE + S++ +S E S
Sbjct: 234 EIRDLKTKTREDPKENRKTKKEKFVESQVESESSVLNDSPFPEDDS 279
>gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]
Length = 295
Score = 40.0 bits (92), Expect = 0.011
Identities = 35/175 (20%), Positives = 69/175 (39%), Gaps = 24/175 (13%)
Query: 13 QDVVLKDEFSSFSELSSASEEDDKEDSAWEPQKKVPRSRKQPPPKESKPKRMPRVKKNAP 72
Q+ +++ + +E E+D+E+ + + P +P P+ P +P P
Sbjct: 34 QEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVP------P 87
Query: 73 QISDGSEVVV-------VKEELNSSVAIADTALEDRKNK-------LDTVQTLKTAKTKQ 118
+I DG V ++++LN A+ + E+RK + D ++ + + +Q
Sbjct: 88 KIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQ 147
Query: 119 KCAAQPHTVRRTKKLKVE----EETSKASNLEGESNSSETPSTSTVWGGTCKKEE 169
+ R +L E EE E E+ + S +GG +K E
Sbjct: 148 QRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKTE 202
>gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens]
Length = 282
Score = 39.7 bits (91), Expect = 0.014
Identities = 34/177 (19%), Positives = 70/177 (39%), Gaps = 24/177 (13%)
Query: 13 QDVVLKDEFSSFSELSSASEEDDKEDSAWEPQKKVPRSRKQPPPKESKPKRMPRVKKNAP 72
Q+ +++ + +E E+D+E+ + + P +P P+ P +P P
Sbjct: 19 QEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVP------P 72
Query: 73 QISDGSEVVV-------VKEELNSSVAIADTALEDRKNK-------LDTVQTLKTAKTKQ 118
+I DG V ++++LN A+ + E+RK + D ++ + + +Q
Sbjct: 73 KIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQ 132
Query: 119 KCAAQPHTVRRTKKLKVE----EETSKASNLEGESNSSETPSTSTVWGGTCKKEEND 171
+ R +L E EE E E+ + S +GG +K + +
Sbjct: 133 QRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKAQTE 189
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 39.3 bits (90), Expect = 0.019
Identities = 53/237 (22%), Positives = 103/237 (43%), Gaps = 19/237 (8%)
Query: 68 KKNAPQISDGSEVVVVKEELNSSVAI----ADTALEDRKNKLDTVQTLKTAKTKQKCAAQ 123
K+N +V ++ +L+ + A+ +DTA RK + ++ + ++ ++ +
Sbjct: 545 KRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQD 604
Query: 124 PHTVRRTKKLKVEEE-TSKASNLEGESNSSETPS--TSTVWGGTCKKEENDDDFTFGQSA 180
+ + T KLK+E+E + S LE E S + + G C EE D G+
Sbjct: 605 KNCLLETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEE---DLKNGKIL 661
Query: 181 LKKIKTETYPQGQPVKFPANANSTKEEVEMNWDMVQVLSERTNIEPWVCANIIRLFNDDN 240
L K++ E Q Q + E++M + + + E A RL D N
Sbjct: 662 LAKVELEK-RQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARL-ADKN 719
Query: 241 TIPFIIRYRKELINNLDADSLREVQQTLEELRAVAKKVHSTIQKIKKEGKMSECLLK 297
I E I +++++E+++ L E R + +KV + + + +K + +C LK
Sbjct: 720 KI-------YESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLK 769
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 39.3 bits (90), Expect = 0.019
Identities = 44/212 (20%), Positives = 83/212 (39%), Gaps = 26/212 (12%)
Query: 22 SSFSELSSASEEDDKEDSAWEPQKKVPRSR---KQPPPKESKPKRMPRVKKNAPQISDGS 78
SS S SS+S++ ++E +A P+K VP+ + K P + P R +++ +
Sbjct: 218 SSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEE 277
Query: 79 EVVVVKEELNSSVAIADTALEDRKNKLDTVQTLKTAKTKQ-------------------- 118
+ +K + ++ + K L T K + +Q
Sbjct: 278 QKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEK 337
Query: 119 KCAAQPHTVRRTKKLKVEEETSKASNLEGESNSSETPSTSTVWGGTCKKEENDDDFTFGQ 178
K + + T K ++ +++S+ +S+SSE + GT K N T
Sbjct: 338 KPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKS 397
Query: 179 SALKKIKTETYPQGQPVKF---PANANSTKEE 207
A+K P G K A+++S++EE
Sbjct: 398 PAVKPAAAPKQPVGGGQKLLTRKADSSSSEEE 429
Score = 34.7 bits (78), Expect = 0.46
Identities = 36/160 (22%), Positives = 59/160 (36%), Gaps = 39/160 (24%)
Query: 22 SSFSELSSASEEDDKEDSAWEPQKKVPR----------------------SRKQPPPKES 59
S S +S++DD+ED +P +K + S + PPK
Sbjct: 124 SESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQ 183
Query: 60 KP-----------KRMPRVKKNAPQISDGSEVVVVKEELNSSVAIADTALEDRKNKLDTV 108
KP K P+ + AP+I++G K +SS + + ++ +D + +
Sbjct: 184 KPKITPVTVKAQTKAPPKPARAAPKIANG------KAASSSSSSSSSSSSDDSEEEKAAA 237
Query: 109 QTLKTAKTKQKCAAQPHTVRRTKKLKVEEETSKASNLEGE 148
KT KQ A P T K +S+ E E
Sbjct: 238 TPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEE 277
Score = 32.7 bits (73), Expect = 1.7
Identities = 35/143 (24%), Positives = 55/143 (38%), Gaps = 9/143 (6%)
Query: 22 SSFSELSSASEEDDKEDSAWEPQKKVPRSRKQPPPKESKPKRMPRVKKNAPQISDGSEVV 81
SS S+ SS+ EE++K + +K + P K + K+ N+ D SE
Sbjct: 470 SSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSE-- 527
Query: 82 VVKEELNSSVAIADTALEDRKNKLDTVQTLKTAKT-------KQKCAAQPHTVRRTKKLK 134
+E+L + A + T Q K AK K+K A KK K
Sbjct: 528 EEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRK 587
Query: 135 VEEETSKASNLEGESNSSETPST 157
E +A + + +TP+T
Sbjct: 588 QNEAAKEAETPQAKKIKLQTPNT 610
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 38.5 bits (88), Expect = 0.032
Identities = 44/188 (23%), Positives = 73/188 (38%), Gaps = 41/188 (21%)
Query: 50 SRKQPPPKESKPKRMPRVKKNAPQISDGSE-------------------VVVVKEELNSS 90
S+K PPKES P P K P +S GS V+++E ++S+
Sbjct: 792 SKKARPPKESAPSSGPPPK---PPVSSGSGSSSSSSSCSSRKVKLQSKVAVLIREGVSST 848
Query: 91 VAIADTAL-----------EDRKNKLDTVQTLKTAKTKQKCAAQPHTVRRTKKLKVEEET 139
D A DR+++ ++ + A T+ AA T + K+K +
Sbjct: 849 TPAKDAASAGLGSIGVKFSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAKAGA 908
Query: 140 SKASNLEGESNSSETPSTSTVWGGTCKKEENDDDFTFGQSALKKIKTETYPQGQPVKFPA 199
K +G++ S+T GG+ + GQ +LKK K ++ Q K
Sbjct: 909 KKTKGTKGKTKPSKTRKKVRSGGGS--------GGSGGQVSLKKSKADSCSQAAGTKGAE 960
Query: 200 NANSTKEE 207
+ + EE
Sbjct: 961 ETSWSGEE 968
Score = 32.0 bits (71), Expect = 3.0
Identities = 38/191 (19%), Positives = 64/191 (33%), Gaps = 36/191 (18%)
Query: 22 SSFSELSSASEEDDKEDSAWEPQKKVPRSRKQPPPKESKPKRMPRVKKNAPQISDGS--- 78
S S A+ E+++W +++ + PPPK + P P Q D S
Sbjct: 945 SKADSCSQAAGTKGAEETSWSGEERAAKVPSTPPPKAAPP---PPALTPDSQTVDSSCKT 1001
Query: 79 -EVVVVKEELNSSVAIADTALEDRKNKLDTVQTLKTAKTKQKCAAQPHTVRRTKKLKVEE 137
EV + EE + A E+ + + ++ + EE
Sbjct: 1002 PEVSFLPEEATEEAGVRGGAEEEEEEE------------------------EEEEEEEEE 1037
Query: 138 ETSKASNLEGESNSSETPSTSTVWGGTCKKEENDDDFTFGQSALKKIKTETYPQGQPVKF 197
E + + S ++ PST+ G T +D A + + T P P
Sbjct: 1038 EEQQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDG-----PASRVSQLPTLPPPMPWNL 1092
Query: 198 PANANSTKEEV 208
PA + T V
Sbjct: 1093 PAGVDCTTSGV 1103
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 37.7 bits (86), Expect = 0.054
Identities = 38/163 (23%), Positives = 62/163 (38%), Gaps = 4/163 (2%)
Query: 16 VLKDEFSSFSELSSASEEDDKEDSAWEPQKKVPRSRKQPPPKESKPKRMPRVKKNAPQIS 75
+L D SS E +ED + EP + K K+ KP+R + K +
Sbjct: 109 LLSDIISSEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKE 168
Query: 76 DGSEVVVVKEELNSSVAIADTALEDRKNKLDTV-QTLKTAKTKQKCAAQ-PHTVRRTKKL 133
G E V KE+ + + K + T+ + K AKT +K + V+ K+
Sbjct: 169 KGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQE 228
Query: 134 KVEEETSKASNLEGESNSSETPSTSTVWGGTCKKEENDDDFTF 176
KV++ +K E + S+ K E D + F
Sbjct: 229 KVKQTAAKVK--EVQKTPSKPKEKEDKEKAAVSKHEQKDQYAF 269
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 37.4 bits (85), Expect = 0.071
Identities = 27/135 (20%), Positives = 60/135 (44%), Gaps = 17/135 (12%)
Query: 17 LKDEFSSFSELSSASEEDDKEDSAWEPQ---------KKVPRSRKQPPPKESKPKRMPRV 67
L DE LSS EE+ +E+ E + K+ ++ KE + K+ +
Sbjct: 2233 LLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKK 2292
Query: 68 KKNAPQISDGSEVVVVKEELNSSVAIADTALEDRKNKLDTVQTLKTAKTKQKCAAQPHTV 127
+K ++ + EV KEE+ S E+ ++ D + ++ +++ + +
Sbjct: 2293 EKKKEEVQEKEEVFEEKEEIMSE--------EETESLSDEEEEEESCSLEEEVDREKEIL 2344
Query: 128 RRTKKLKVEEETSKA 142
++ K+ K++E+ K+
Sbjct: 2345 KKEKQFKLQEQRRKS 2359
Score = 35.0 bits (79), Expect = 0.35
Identities = 80/378 (21%), Positives = 142/378 (37%), Gaps = 56/378 (14%)
Query: 6 RRAKVQVQDVVLKDEFSSFSELSSASEEDDKEDSAWEPQKKVPRSRKQPPPKESKPKRMP 65
+R VQ Q + K + S S+E K + + +K+ R ++ +E K +M
Sbjct: 2042 QRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMK 2101
Query: 66 RVKKNAPQISDGSEVVVVKEEL----NSSVAIADTALEDRKNKLDTVQTLKTAKTKQKCA 121
R + VKE S + I + +++++L T K A+ ++K A
Sbjct: 2102 RA-------------LFVKERRLSIEQSKLDIKEWDFSEKRSEL-TKDEKKLARKQRKLA 2147
Query: 122 AQPHTVRR--TKKLKVEEETSKASNLEGESNSSETPSTSTVWGGTCKKEENDDDFTFGQS 179
+ +RR K+ K+ EE SK + E + GG E ++ F +
Sbjct: 2148 ---NKMRRMINKEEKMTEEESKLARKHSEVILDDEEE-----GGI----EEEEVIPFLKR 2195
Query: 180 ALKKIKTETYPQGQPVKFPANANSTKEEVEMNWDMVQVLSERTNIEPWVCANIIRLFNDD 239
+K K KF + + + E + +M +L E E L +++
Sbjct: 2196 RWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQES--------LSSEE 2247
Query: 240 NTIPFIIRYRKELINNLDADSLREVQQTLEELRAVAKKVHSTIQ---KIKKEGKMSECLL 296
R+E + + E ++ EE K+V + K KKE K E
Sbjct: 2248 E------EEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQE 2301
Query: 297 KAMLNCKTFEELEHVSAPYKTGSKGTKAQRARQLGLE---GAARALLEKPGELSLLSYIR 353
K + FEE E + + +T S + + LE + +L+K + L R
Sbjct: 2302 KE----EVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRR 2357
Query: 354 PDVKGLSTLQDIEIGVQH 371
++G + I GV H
Sbjct: 2358 KSLRGRERVLSILRGVPH 2375
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 37.4 bits (85), Expect = 0.071
Identities = 68/294 (23%), Positives = 111/294 (37%), Gaps = 30/294 (10%)
Query: 12 VQDVVLKDEFSSFSELSSASEEDDKEDSAWEPQKKVPRSRK-----QPPPKESKPKRMPR 66
V+ LK S L A++ + E +++ P K +PP ESK K M
Sbjct: 530 VKQTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVM-- 587
Query: 67 VKKNAPQISDGSEVVVVKEELNSSVAIADTALEDRKNKLDTVQTLKTAKTKQKCAAQPHT 126
VKK+ P +K E SV + ++ + + K A + AA+ T
Sbjct: 588 VKKDKP----------IKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKT 637
Query: 127 VRRTKKLKVEEETSKASNLEGESNSSETPSTSTVWGGTCKKEENDDDFTFGQSALKKIKT 186
V++ K+K E++ + + E E + KKEE + K+IK
Sbjct: 638 VKKETKVKPEDKKEEKEKPKKEVAKKEDKT-------PIKKEEKPKKEEVKKEVKKEIKK 690
Query: 187 ETYPQ-GQPVKFPANANSTKEEVEMNWDMVQVLSERTNIEPWVCANIIRLFNDDNTIPFI 245
E + + VK K+EV+ + +V E EP I +L D
Sbjct: 691 EEKKEPKKEVKKETPPKEVKKEVKKE-EKKEVKKEEK--EP--KKEIKKLPKDAKKSSTP 745
Query: 246 IRYRKELINNLDADSLREVQQTLEELRAVAKKVHSTIQKIKKEGKMSECLLKAM 299
+ K+ +E + + A K I+ IKKEGK +E + A+
Sbjct: 746 LSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAV 799
Score = 34.3 bits (77), Expect = 0.60
Identities = 65/322 (20%), Positives = 118/322 (36%), Gaps = 52/322 (16%)
Query: 8 AKVQVQDVVLKDEFSSFSELSSASEEDDKEDSAWEPQKKVPRSR-KQPPPKESKPKR--- 63
A+ Q DV K + + + +DK++ +P+K+V + K P KE KPK+
Sbjct: 621 AEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEV 680
Query: 64 ----------------MPRVKKNAP------QISDGSEVVVVKEELNSSVAIADTALEDR 101
VKK P ++ + V KEE I + +
Sbjct: 681 KKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAK 740
Query: 102 KNKLDTVQTLKTAKTKQKCAAQPHTVRRTKKLKVE-EETSKASNLEGESNSSETPSTSTV 160
K+ + K A K K + +V++ + +E K ++ E ++E + +
Sbjct: 741 KSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVG 800
Query: 161 WGGTCKKEENDDDFTFGQSAL---KKIKTETYPQGQPVKFPANANSTK-EEVEMNWDMVQ 216
G T G +A+ K+++ E P + K EEV++ D+
Sbjct: 801 TGATTAAVM----AAAGIAAIGPAKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKP 856
Query: 217 VLSERTNIEPWVCANIIRLFNDDNTIPFIIRYRKELINN---------LDADSLREVQQT 267
L + E +L + ++I+ +E+ + E +QT
Sbjct: 857 QLELIEDEE--------KLKETEPVEAYVIQKEREVTKGPAESPDEGITTTEGEGECEQT 908
Query: 268 LEELRAVAKKVHSTIQKIKKEG 289
EEL V K+ I+K + EG
Sbjct: 909 PEELEPVEKQGVDDIEKFEDEG 930
Score = 33.1 bits (74), Expect = 1.3
Identities = 39/160 (24%), Positives = 55/160 (34%), Gaps = 24/160 (15%)
Query: 57 KESKPKRMPRVKKNAPQISDGSEVVVVKEELNSSVAIADTALEDRKNKLDTVQTLKTAKT 116
K K + K P S V K + S A K D V + + K
Sbjct: 2233 KALKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPKK 2292
Query: 117 KQKC--AAQPHTVRRTKKLKVEEETSKASNLEGESNSSETPSTSTVWGGTCKKEENDDDF 174
K+ AA+P T K + EE+ + N +N+S + S T
Sbjct: 2293 KESVEKAAKPTTTPEVKAARGEEKDKETKN---AANASASKSAKTA-------------- 2335
Query: 175 TFGQSALKKIKTETYPQGQPV-----KFPANANSTKEEVE 209
T G K K+ P G PV P ++NS +VE
Sbjct: 2336 TAGPGTTKTTKSSAVPPGLPVYLDLCYIPNHSNSKNVDVE 2375
>gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1
[Homo sapiens]
Length = 871
Score = 37.0 bits (84), Expect = 0.092
Identities = 28/86 (32%), Positives = 46/86 (53%), Gaps = 8/86 (9%)
Query: 436 ILAINRGENLKVLTVKVNISDGVKDEFCRWC--IQNRWRPRSFARPELMKILYNSLNDSF 493
ILA+ E LT KV SD ++ EF R C + NRWR + FA +K +DS
Sbjct: 393 ILALQEEE----LTRKVQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSV 448
Query: 494 KRLIYPLLCREFRAKLTSDAEKESVM 519
K+L + + K+TS +++++++
Sbjct: 449 KQLKGQV--ASLQEKVTSQSQEQAIL 472
>gi|157738613 coiled-coil alpha-helical rod protein 1 isoform 2
[Homo sapiens]
Length = 835
Score = 37.0 bits (84), Expect = 0.092
Identities = 28/86 (32%), Positives = 46/86 (53%), Gaps = 8/86 (9%)
Query: 436 ILAINRGENLKVLTVKVNISDGVKDEFCRWC--IQNRWRPRSFARPELMKILYNSLNDSF 493
ILA+ E LT KV SD ++ EF R C + NRWR + FA +K +DS
Sbjct: 357 ILALQEEE----LTRKVQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSV 412
Query: 494 KRLIYPLLCREFRAKLTSDAEKESVM 519
K+L + + K+TS +++++++
Sbjct: 413 KQLKGQV--ASLQEKVTSQSQEQAIL 436
>gi|157738611 coiled-coil alpha-helical rod protein 1 isoform 3
[Homo sapiens]
Length = 782
Score = 37.0 bits (84), Expect = 0.092
Identities = 28/86 (32%), Positives = 46/86 (53%), Gaps = 8/86 (9%)
Query: 436 ILAINRGENLKVLTVKVNISDGVKDEFCRWC--IQNRWRPRSFARPELMKILYNSLNDSF 493
ILA+ E LT KV SD ++ EF R C + NRWR + FA +K +DS
Sbjct: 304 ILALQEEE----LTRKVQPSDSLEPEFTRKCQSLLNRWREKVFALMVQLKAQELEHSDSV 359
Query: 494 KRLIYPLLCREFRAKLTSDAEKESVM 519
K+L + + K+TS +++++++
Sbjct: 360 KQLKGQV--ASLQEKVTSQSQEQAIL 383
>gi|30061491 erythrocyte membrane protein band 4.1-like 1 isoform b
[Homo sapiens]
Length = 779
Score = 36.6 bits (83), Expect = 0.12
Identities = 39/143 (27%), Positives = 67/143 (46%), Gaps = 17/143 (11%)
Query: 13 QDVVLKDEFSSFSELSSASEEDDKE----DSAWEPQKKVPRSRKQPPPKESKPKRMPRVK 68
+DV+LK + +S +EL +E + + D WE ++++P S P PK + K R
Sbjct: 427 EDVLLKHQ-ASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANERA- 484
Query: 69 KNAPQISDGSEVVVVKEELNSSVAIADTALEDRKNKLDTVQTLKT--AKTKQKCAAQPHT 126
+ +GSE V + +DT ED+ + DTV LK ++KC++ T
Sbjct: 485 ----GLREGSEEKV--KPPRPRAPESDTGDEDQDQERDTV-FLKDNHLAIERKCSS--IT 535
Query: 127 VRRTKKLKVEEETSKASNLEGES 149
V T L+ E + + + G +
Sbjct: 536 VSSTSSLEAEVDFTVIGDYHGSA 558
>gi|30061489 erythrocyte membrane protein band 4.1-like 1 isoform a
[Homo sapiens]
Length = 881
Score = 36.6 bits (83), Expect = 0.12
Identities = 39/143 (27%), Positives = 67/143 (46%), Gaps = 17/143 (11%)
Query: 13 QDVVLKDEFSSFSELSSASEEDDKE----DSAWEPQKKVPRSRKQPPPKESKPKRMPRVK 68
+DV+LK + +S +EL +E + + D WE ++++P S P PK + K R
Sbjct: 501 EDVLLKHQ-ASINELKRTLKEPNSKLIHRDRDWERERRLPSSPASPSPKGTPEKANERA- 558
Query: 69 KNAPQISDGSEVVVVKEELNSSVAIADTALEDRKNKLDTVQTLKT--AKTKQKCAAQPHT 126
+ +GSE V + +DT ED+ + DTV LK ++KC++ T
Sbjct: 559 ----GLREGSEEKV--KPPRPRAPESDTGDEDQDQERDTV-FLKDNHLAIERKCSS--IT 609
Query: 127 VRRTKKLKVEEETSKASNLEGES 149
V T L+ E + + + G +
Sbjct: 610 VSSTSSLEAEVDFTVIGDYHGSA 632
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 36.6 bits (83), Expect = 0.12
Identities = 39/197 (19%), Positives = 80/197 (40%), Gaps = 9/197 (4%)
Query: 28 SSASEEDDKEDSAWEPQKKVPRSRKQPPPKESKPKRMPRVKKNAPQISDGSEVVVVKEEL 87
S +S+ DD+E QK+ RK+ + K+M K+ +++ + KE+
Sbjct: 405 SESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQN 464
Query: 88 NSSVAIADTALEDRKNKLDTVQTLKTAKTKQKCAAQPHTVRRTKKLKVEEETSKASNLEG 147
+ S+ LE R+ D V K + +P + K+ + + +S+
Sbjct: 465 SLSL------LEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSS 518
Query: 148 ESNSSETPSTSTVWGGTCKKEENDDDFTFGQSALKKIKTETYPQGQPVK---FPANANST 204
SNS + ++STV + + S+ K+ K + + +K + + S
Sbjct: 519 SSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSR 578
Query: 205 KEEVEMNWDMVQVLSER 221
+ ++E N V++ R
Sbjct: 579 RIKIESNRARVKIRDRR 595
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 36.6 bits (83), Expect = 0.12
Identities = 39/197 (19%), Positives = 80/197 (40%), Gaps = 9/197 (4%)
Query: 28 SSASEEDDKEDSAWEPQKKVPRSRKQPPPKESKPKRMPRVKKNAPQISDGSEVVVVKEEL 87
S +S+ DD+E QK+ RK+ + K+M K+ +++ + KE+
Sbjct: 405 SESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQN 464
Query: 88 NSSVAIADTALEDRKNKLDTVQTLKTAKTKQKCAAQPHTVRRTKKLKVEEETSKASNLEG 147
+ S+ LE R+ D V K + +P + K+ + + +S+
Sbjct: 465 SLSL------LEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSS 518
Query: 148 ESNSSETPSTSTVWGGTCKKEENDDDFTFGQSALKKIKTETYPQGQPVK---FPANANST 204
SNS + ++STV + + S+ K+ K + + +K + + S
Sbjct: 519 SSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSR 578
Query: 205 KEEVEMNWDMVQVLSER 221
+ ++E N V++ R
Sbjct: 579 RIKIESNRARVKIRDRR 595
>gi|61743963 chromobox homolog 2 isoform 1 [Homo sapiens]
Length = 532
Score = 36.2 bits (82), Expect = 0.16
Identities = 25/77 (32%), Positives = 40/77 (51%), Gaps = 5/77 (6%)
Query: 1 MSSLPRRAKVQVQDVVLKDEFSSFSELS-SASEEDDKEDSAWEPQKKVPRSRKQPPPKES 59
MSS RR+K++ D K + SS S S S+S D+ED + K+ PR R+ P
Sbjct: 86 MSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEDDSDLDAKRGPRGRETHP---- 141
Query: 60 KPKRMPRVKKNAPQISD 76
P++ ++ P++ D
Sbjct: 142 VPQKKAQILVAKPELKD 158
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 35.8 bits (81), Expect = 0.21
Identities = 63/302 (20%), Positives = 132/302 (43%), Gaps = 37/302 (12%)
Query: 17 LKDEFSSFSELSSASEEDDKEDSAWEPQKKVPRSRKQPPPKESKPKRMPRVKKNAPQISD 76
LK+ + +E EED ++ A + + + + ++ R + + D
Sbjct: 1412 LKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDD 1471
Query: 77 GSEVVVVK-EELNSSVAIADTALEDRKNKLDTVQTLKTAKTKQKCAAQPHTVRRTKKLKV 135
++ + K +E+ + D DRK D L+ + + A T KLKV
Sbjct: 1472 AAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSAT-ETINKLKV 1530
Query: 136 EEETSKASNLEGESNSSETPSTSTVWGGTCKKEENDDDFTFGQSALKKI---KTETYPQG 192
+E+ ++ E S E + D D T Q++LK++ K + +
Sbjct: 1531 QEQELTRLRIDYERVSQE-------------RTVKDQDITRFQNSLKELQLQKQKVEEEL 1577
Query: 193 QPVKFPANANSTK-----EEVE-MNWDMVQVLSERTNIEPWV-CANIIRLFNDDNTIPFI 245
+K A+ +S K EE+E M + + + TN+ + A+I++ ++D+
Sbjct: 1578 NRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDD----- 1632
Query: 246 IRYRKELINNLDADSLREVQQTLEELRAVAKKVHSTIQKIKKEGKMSECLLKAMLNCKTF 305
+R ++++++ LRE Q+T EELR ++ +V + +++ +E E + +A L + F
Sbjct: 1633 LRQQRDVLDG----HLREKQRTQEELRRLSSEVEALRRQLLQE---QESVKQAHLRNEHF 1685
Query: 306 EE 307
++
Sbjct: 1686 QK 1687
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 35.8 bits (81), Expect = 0.21
Identities = 45/189 (23%), Positives = 69/189 (36%), Gaps = 36/189 (19%)
Query: 22 SSFSELSSASEEDDKEDSAWEPQKKVPRSRKQPPP-----------KESK---------- 60
SS EL + K+ S + ++P+ K PPP KE+K
Sbjct: 213 SSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGP 272
Query: 61 ---PKRMPRVKKNAPQISDGSEVVVVKEELNSSVAIADT-ALEDRKNKLDTVQTLKTAKT 116
P PR P +D + K++ +SS R + + K AK
Sbjct: 273 PPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKD 332
Query: 117 K-----QKCAAQPHTVRRTKKLKVEEETSKASNLEGESN-SSETPSTSTVWGGTCKKEEN 170
K +K A+ K L+VEE SN E E++ SE+ +S + +
Sbjct: 333 KSSTRGEKVKAESEPREAKKALEVEE-----SNSEDEASFKSESAQSSPSNSSSSSDSSS 387
Query: 171 DDDFTFGQS 179
D DF Q+
Sbjct: 388 DSDFEPSQN 396
Score = 31.6 bits (70), Expect = 3.9
Identities = 43/203 (21%), Positives = 79/203 (38%), Gaps = 21/203 (10%)
Query: 28 SSASEEDDKEDSAWEPQKKVPRSRKQPPPKESKPKRMPR--VKKNAPQISDGS----EVV 81
S S++ +KE S KV + ++ P K+S+ K + ++ A D S E
Sbjct: 178 SHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGR 237
Query: 82 VVKEELNSSVAIADTALEDRKNKLDTVQTLKTAKTKQKCAAQPHTVRRTKKLKVEEETSK 141
+ KEE A ++ K L + T+ P R + K ++ K
Sbjct: 238 LPKEE---KAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPK 294
Query: 142 ASNLEGESNSSE--------TPSTSTVWGGTCKKEENDDDFTFGQSALKKIKTETYPQGQ 193
S + + +SS+ +P TS+ + KK D T G+ K+K E+ P+
Sbjct: 295 PSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGE----KVKAESEPREA 350
Query: 194 PVKFPANANSTKEEVEMNWDMVQ 216
+++++E + Q
Sbjct: 351 KKALEVEESNSEDEASFKSESAQ 373
>gi|154354974 phosphatase and actin regulator 2 isoform 3 [Homo
sapiens]
Length = 634
Score = 35.8 bits (81), Expect = 0.21
Identities = 49/196 (25%), Positives = 84/196 (42%), Gaps = 30/196 (15%)
Query: 13 QDVVLKDEFS-SFSELSSASEE--DDKEDSAWEPQKKVPRSRKQPPPKESKPKRMPRVKK 69
++VV +E + S SE + EE +DK+++ E + P + PP KP+ P+ KK
Sbjct: 113 ENVVKSEEGNGSVSEKTPPLEEQAEDKKENT-ENHSETPAAPALPPSAPPKPRPKPKPKK 171
Query: 70 N--------APQISDGSEVVVVKEELNSSVAIADTALEDRKNKLDTVQTLKTAKTKQ--- 118
+ A G EV +K+ + A ++ T + ++ +K+
Sbjct: 172 SPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTG 231
Query: 119 -KCAAQPHTVRRTKKLKVEEET--SKASNL---EGESNSSETPSTSTVWGGTCKKEENDD 172
K +A P T + + K +ET SKA + +G+ + + P TS + + D
Sbjct: 232 SKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHL---------SSD 282
Query: 173 DFTFGQSALKKIKTET 188
T G S LK ET
Sbjct: 283 TTTSGTSDLKGEPAET 298
>gi|154354968 phosphatase and actin regulator 2 isoform 1 [Homo
sapiens]
Length = 645
Score = 35.8 bits (81), Expect = 0.21
Identities = 49/196 (25%), Positives = 84/196 (42%), Gaps = 30/196 (15%)
Query: 13 QDVVLKDEFS-SFSELSSASEE--DDKEDSAWEPQKKVPRSRKQPPPKESKPKRMPRVKK 69
++VV +E + S SE + EE +DK+++ E + P + PP KP+ P+ KK
Sbjct: 124 ENVVKSEEGNGSVSEKTPPLEEQAEDKKENT-ENHSETPAAPALPPSAPPKPRPKPKPKK 182
Query: 70 N--------APQISDGSEVVVVKEELNSSVAIADTALEDRKNKLDTVQTLKTAKTKQ--- 118
+ A G EV +K+ + A ++ T + ++ +K+
Sbjct: 183 SPVPPKGATAGASHKGDEVPPIKKNTKAPGKQAPVPPPKPASRNTTREAAGSSHSKKTTG 242
Query: 119 -KCAAQPHTVRRTKKLKVEEET--SKASNL---EGESNSSETPSTSTVWGGTCKKEENDD 172
K +A P T + + K +ET SKA + +G+ + + P TS + + D
Sbjct: 243 SKASASPSTSSTSSRPKASKETVSSKAGTVGTTKGKRKTDKQPITSHL---------SSD 293
Query: 173 DFTFGQSALKKIKTET 188
T G S LK ET
Sbjct: 294 TTTSGTSDLKGEPAET 309
>gi|6453818 kinesin family member 22 [Homo sapiens]
Length = 665
Score = 35.8 bits (81), Expect = 0.21
Identities = 18/52 (34%), Positives = 30/52 (57%), Gaps = 3/52 (5%)
Query: 718 LRHIAGLNANRAKNIIEWREKNGPFINREQLKKVKGLGPKSFQQCAGFIRIN 769
LR + + +A+ I+ WRE +GPF E L++V+G+ K Q F++ N
Sbjct: 604 LRSLQRIGPKKAQLIVGWRELHGPFSQVEDLERVEGITGK---QMESFLKAN 652
>gi|225543215 antigen identified by monoclonal antibody Ki-67 isoform
2 [Homo sapiens]
Length = 2896
Score = 35.4 bits (80), Expect = 0.27
Identities = 42/150 (28%), Positives = 70/150 (46%), Gaps = 21/150 (14%)
Query: 17 LKDEFSSFSELSSASEEDD---KEDSAWEPQKKV--PRSRKQPPPKESKP-KRMPRV-KK 69
+K+E S+ L+ S + KE ++ + KV R++K+P P E +P +R PR K+
Sbjct: 2252 VKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKE 2311
Query: 70 NAPQISDGSEVVVVKE----ELNSSVAIADTALEDRKNKLDTVQTLKTAKTKQKCAAQPH 125
A + D + + E S A T + L+ V T TA TK+ H
Sbjct: 2312 KAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDT--TASTKR------H 2363
Query: 126 TVRRTKKLKVEEETS--KASNLEGESNSSE 153
R +K++V+EE S K + GE+ ++
Sbjct: 2364 LRTRVQKVQVKEEPSAVKFTQTSGETTDAD 2393
Score = 34.7 bits (78), Expect = 0.46
Identities = 43/192 (22%), Positives = 81/192 (42%), Gaps = 19/192 (9%)
Query: 2 SSLPRRAKVQVQDVVLKDEFSS--FSELSSASEEDDKEDSAWEPQ-KKVPRSRKQPPPKE 58
+S R + +VQ V +K+E S+ F++ S + + DKE + + K + S KQ P
Sbjct: 2358 ASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPA 2417
Query: 59 SK---PKRMPRVKKNAPQISDGSEVVVVKEELNSSVAIADTALEDRKNKLDTVQTLKTAK 115
+ +R PR + + Q + ++ K+ ++ ++ +D+ K+ + +
Sbjct: 2418 ASVTGSRRRPRAPRESAQAIE--DLAGFKDP--AAGHTEESMTDDKTTKIPCKSSPELED 2473
Query: 116 TKQKCAAQPHTVRRTKKLKVEEETSKASNLEGESNSSETPSTSTVWGGTCKKEENDDDFT 175
T +P T R +K++V+EE L S + V G K
Sbjct: 2474 TATSSKRRPRT--RAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTK-------A 2524
Query: 176 FGQSALKKIKTE 187
F Q A +K+ E
Sbjct: 2525 FKQPAKRKLDAE 2536
>gi|103472005 antigen identified by monoclonal antibody Ki-67 isoform
1 [Homo sapiens]
Length = 3256
Score = 35.4 bits (80), Expect = 0.27
Identities = 42/150 (28%), Positives = 70/150 (46%), Gaps = 21/150 (14%)
Query: 17 LKDEFSSFSELSSASEEDD---KEDSAWEPQKKV--PRSRKQPPPKESKP-KRMPRV-KK 69
+K+E S+ L+ S + KE ++ + KV R++K+P P E +P +R PR K+
Sbjct: 2612 VKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKE 2671
Query: 70 NAPQISDGSEVVVVKE----ELNSSVAIADTALEDRKNKLDTVQTLKTAKTKQKCAAQPH 125
A + D + + E S A T + L+ V T TA TK+ H
Sbjct: 2672 KAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDT--TASTKR------H 2723
Query: 126 TVRRTKKLKVEEETS--KASNLEGESNSSE 153
R +K++V+EE S K + GE+ ++
Sbjct: 2724 LRTRVQKVQVKEEPSAVKFTQTSGETTDAD 2753
Score = 34.7 bits (78), Expect = 0.46
Identities = 43/192 (22%), Positives = 81/192 (42%), Gaps = 19/192 (9%)
Query: 2 SSLPRRAKVQVQDVVLKDEFSS--FSELSSASEEDDKEDSAWEPQ-KKVPRSRKQPPPKE 58
+S R + +VQ V +K+E S+ F++ S + + DKE + + K + S KQ P
Sbjct: 2718 ASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPA 2777
Query: 59 SK---PKRMPRVKKNAPQISDGSEVVVVKEELNSSVAIADTALEDRKNKLDTVQTLKTAK 115
+ +R PR + + Q + ++ K+ ++ ++ +D+ K+ + +
Sbjct: 2778 ASVTGSRRRPRAPRESAQAIE--DLAGFKDP--AAGHTEESMTDDKTTKIPCKSSPELED 2833
Query: 116 TKQKCAAQPHTVRRTKKLKVEEETSKASNLEGESNSSETPSTSTVWGGTCKKEENDDDFT 175
T +P T R +K++V+EE L S + V G K
Sbjct: 2834 TATSSKRRPRT--RAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTK-------A 2884
Query: 176 FGQSALKKIKTE 187
F Q A +K+ E
Sbjct: 2885 FKQPAKRKLDAE 2896
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,172,293
Number of Sequences: 37866
Number of extensions: 1621247
Number of successful extensions: 7536
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 138
Number of HSP's that attempted gapping in prelim test: 7213
Number of HSP's gapped (non-prelim): 438
length of query: 995
length of database: 18,247,518
effective HSP length: 112
effective length of query: 883
effective length of database: 14,006,526
effective search space: 12367762458
effective search space used: 12367762458
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.