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Search of human proteins with 22035620
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22035620 PYD and CARD domain containing isoform b [Homo
sapiens]
(176 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22035620 PYD and CARD domain containing isoform b [Homo sapiens] 348 1e-96
gi|10835256 PYD and CARD domain containing isoform a [Homo sapiens] 337 4e-93
gi|23097246 pyrin domain containing 1 [Homo sapiens] 107 5e-24
gi|7662386 NLR family, pyrin domain containing 1 isoform 2 [Homo... 96 2e-20
gi|14719835 NLR family, pyrin domain containing 1 isoform 4 [Hom... 96 2e-20
gi|14719833 NLR family, pyrin domain containing 1 isoform 3 [Hom... 96 2e-20
gi|14719829 NLR family, pyrin domain containing 1 isoform 1 [Hom... 96 2e-20
gi|4557743 Mediterranean fever protein [Homo sapiens] 52 3e-07
gi|21264320 NLR family, pyrin domain containing 6 [Homo sapiens] 49 2e-06
gi|28827807 NLR family, pyrin domain containing 10 [Homo sapiens] 47 1e-05
gi|187937176 NACHT, leucine rich repeat and PYD containing 7 iso... 40 0.001
gi|75709196 NACHT, leucine rich repeat and PYD containing 7 isof... 40 0.001
gi|46049100 NACHT, leucine rich repeat and PYD containing 7 isof... 40 0.001
gi|7662404 caspase recruitment domain family, member 8 [Homo sap... 39 0.002
gi|119395764 NLR family, pyrin domain containing 3 isoform a [Ho... 35 0.026
gi|188536116 NLR family, pyrin domain containing 3 isoform c [Ho... 35 0.026
gi|188536002 NLR family, pyrin domain containing 3 isoform d [Ho... 35 0.026
gi|34878693 NLR family, pyrin domain containing 3 isoform a [Hom... 35 0.026
gi|34878690 NLR family, pyrin domain containing 3 isoform b [Hom... 35 0.026
gi|21955154 NLR family, pyrin domain containing 12 isoform 2 [Ho... 33 0.17
gi|5174617 nucleotide-binding oligomerization domain containing ... 32 0.22
gi|4506537 receptor-interacting serine-threonine kinase 2 [Homo ... 30 1.4
gi|194018482 NLR family, pyrin domain containing 4 [Homo sapiens] 30 1.4
gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens] 30 1.4
gi|74271814 NLR family, pyrin domain containing 1 isoform 5 [Hom... 28 3.1
gi|8923473 NLR family, pyrin domain containing 2 [Homo sapiens] 27 9.2
gi|4505419 nucleolar protein 3 [Homo sapiens] 27 9.2
gi|66529203 hypothetical protein LOC57714 [Homo sapiens] 27 9.2
>gi|22035620 PYD and CARD domain containing isoform b [Homo sapiens]
Length = 176
Score = 348 bits (893), Expect = 1e-96
Identities = 176/176 (100%), Positives = 176/176 (100%)
Query: 1 MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFY 60
MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFY
Sbjct: 1 MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFY 60
Query: 61 LETYGAELTANVLRDMGLQEMAGQLQAATHQGLHFIDQHRAALIARVTNVEWLLDALYGK 120
LETYGAELTANVLRDMGLQEMAGQLQAATHQGLHFIDQHRAALIARVTNVEWLLDALYGK
Sbjct: 61 LETYGAELTANVLRDMGLQEMAGQLQAATHQGLHFIDQHRAALIARVTNVEWLLDALYGK 120
Query: 121 VLTDEQYQAVRAEPTNPSKMRKLFSFTPAWNWTCKDLLLQALRESQSYLVEDLERS 176
VLTDEQYQAVRAEPTNPSKMRKLFSFTPAWNWTCKDLLLQALRESQSYLVEDLERS
Sbjct: 121 VLTDEQYQAVRAEPTNPSKMRKLFSFTPAWNWTCKDLLLQALRESQSYLVEDLERS 176
>gi|10835256 PYD and CARD domain containing isoform a [Homo sapiens]
Length = 195
Score = 337 bits (863), Expect = 4e-93
Identities = 176/195 (90%), Positives = 176/195 (90%), Gaps = 19/195 (9%)
Query: 1 MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFY 60
MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFY
Sbjct: 1 MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFY 60
Query: 61 LETYGAELTANVLRDMGLQEMAGQLQAATHQ-------------------GLHFIDQHRA 101
LETYGAELTANVLRDMGLQEMAGQLQAATHQ GLHFIDQHRA
Sbjct: 61 LETYGAELTANVLRDMGLQEMAGQLQAATHQGSGAAPAGIQAPPQSAAKPGLHFIDQHRA 120
Query: 102 ALIARVTNVEWLLDALYGKVLTDEQYQAVRAEPTNPSKMRKLFSFTPAWNWTCKDLLLQA 161
ALIARVTNVEWLLDALYGKVLTDEQYQAVRAEPTNPSKMRKLFSFTPAWNWTCKDLLLQA
Sbjct: 121 ALIARVTNVEWLLDALYGKVLTDEQYQAVRAEPTNPSKMRKLFSFTPAWNWTCKDLLLQA 180
Query: 162 LRESQSYLVEDLERS 176
LRESQSYLVEDLERS
Sbjct: 181 LRESQSYLVEDLERS 195
>gi|23097246 pyrin domain containing 1 [Homo sapiens]
Length = 89
Score = 107 bits (267), Expect = 5e-24
Identities = 57/88 (64%), Positives = 66/88 (75%)
Query: 1 MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFY 60
MG R+AIL LENLT EELKKFK+KL +VPLREG+ RIPRGAL +D +DLTDKLV+ Y
Sbjct: 1 MGTKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDKLVASY 60
Query: 61 LETYGAELTANVLRDMGLQEMAGQLQAA 88
E Y AEL VLRDM + E A +LQ A
Sbjct: 61 YEDYAAELVVAVLRDMRMLEEAARLQRA 88
>gi|7662386 NLR family, pyrin domain containing 1 isoform 2 [Homo
sapiens]
Length = 1429
Score = 95.9 bits (237), Expect = 2e-20
Identities = 47/83 (56%), Positives = 64/83 (77%)
Query: 91 QGLHFIDQHRAALIARVTNVEWLLDALYGKVLTDEQYQAVRAEPTNPSKMRKLFSFTPAW 150
Q LHF+DQ+R LIARVT+VE +LD L+G+VL+ EQY+ V AE T PS+MRKLFS + +W
Sbjct: 1333 QLLHFVDQYREQLIARVTSVEVVLDKLHGQVLSQEQYERVLAENTRPSQMRKLFSLSQSW 1392
Query: 151 NWTCKDLLLQALRESQSYLVEDL 173
+ CKD L QAL+E+ +L+ +L
Sbjct: 1393 DRKCKDGLYQALKETHPHLIMEL 1415
Score = 28.5 bits (62), Expect = 3.1
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 12 LENLTAEELKKFKLKLLS-VPLREGYGRIPRGALLSMDALDLTDKLVSFYLETYGAELTA 70
LE L EELK+F+L L + R G P +++ LV+ Y E +L
Sbjct: 13 LEFLKKEELKEFQLLLANKAHSRSSSGETP-AQPEKTSGMEVASYLVAQYGEQRAWDLAL 71
Query: 71 NVLRDMGLQEMAGQLQ 86
+ MGL+ + Q Q
Sbjct: 72 HTWEQMGLRSLCAQAQ 87
>gi|14719835 NLR family, pyrin domain containing 1 isoform 4 [Homo
sapiens]
Length = 1399
Score = 95.9 bits (237), Expect = 2e-20
Identities = 47/83 (56%), Positives = 64/83 (77%)
Query: 91 QGLHFIDQHRAALIARVTNVEWLLDALYGKVLTDEQYQAVRAEPTNPSKMRKLFSFTPAW 150
Q LHF+DQ+R LIARVT+VE +LD L+G+VL+ EQY+ V AE T PS+MRKLFS + +W
Sbjct: 1303 QLLHFVDQYREQLIARVTSVEVVLDKLHGQVLSQEQYERVLAENTRPSQMRKLFSLSQSW 1362
Query: 151 NWTCKDLLLQALRESQSYLVEDL 173
+ CKD L QAL+E+ +L+ +L
Sbjct: 1363 DRKCKDGLYQALKETHPHLIMEL 1385
Score = 28.5 bits (62), Expect = 3.1
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 12 LENLTAEELKKFKLKLLS-VPLREGYGRIPRGALLSMDALDLTDKLVSFYLETYGAELTA 70
LE L EELK+F+L L + R G P +++ LV+ Y E +L
Sbjct: 13 LEFLKKEELKEFQLLLANKAHSRSSSGETP-AQPEKTSGMEVASYLVAQYGEQRAWDLAL 71
Query: 71 NVLRDMGLQEMAGQLQ 86
+ MGL+ + Q Q
Sbjct: 72 HTWEQMGLRSLCAQAQ 87
>gi|14719833 NLR family, pyrin domain containing 1 isoform 3 [Homo
sapiens]
Length = 1443
Score = 95.9 bits (237), Expect = 2e-20
Identities = 47/83 (56%), Positives = 64/83 (77%)
Query: 91 QGLHFIDQHRAALIARVTNVEWLLDALYGKVLTDEQYQAVRAEPTNPSKMRKLFSFTPAW 150
Q LHF+DQ+R LIARVT+VE +LD L+G+VL+ EQY+ V AE T PS+MRKLFS + +W
Sbjct: 1347 QLLHFVDQYREQLIARVTSVEVVLDKLHGQVLSQEQYERVLAENTRPSQMRKLFSLSQSW 1406
Query: 151 NWTCKDLLLQALRESQSYLVEDL 173
+ CKD L QAL+E+ +L+ +L
Sbjct: 1407 DRKCKDGLYQALKETHPHLIMEL 1429
Score = 28.5 bits (62), Expect = 3.1
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 12 LENLTAEELKKFKLKLLS-VPLREGYGRIPRGALLSMDALDLTDKLVSFYLETYGAELTA 70
LE L EELK+F+L L + R G P +++ LV+ Y E +L
Sbjct: 13 LEFLKKEELKEFQLLLANKAHSRSSSGETP-AQPEKTSGMEVASYLVAQYGEQRAWDLAL 71
Query: 71 NVLRDMGLQEMAGQLQ 86
+ MGL+ + Q Q
Sbjct: 72 HTWEQMGLRSLCAQAQ 87
>gi|14719829 NLR family, pyrin domain containing 1 isoform 1 [Homo
sapiens]
Length = 1473
Score = 95.9 bits (237), Expect = 2e-20
Identities = 47/83 (56%), Positives = 64/83 (77%)
Query: 91 QGLHFIDQHRAALIARVTNVEWLLDALYGKVLTDEQYQAVRAEPTNPSKMRKLFSFTPAW 150
Q LHF+DQ+R LIARVT+VE +LD L+G+VL+ EQY+ V AE T PS+MRKLFS + +W
Sbjct: 1377 QLLHFVDQYREQLIARVTSVEVVLDKLHGQVLSQEQYERVLAENTRPSQMRKLFSLSQSW 1436
Query: 151 NWTCKDLLLQALRESQSYLVEDL 173
+ CKD L QAL+E+ +L+ +L
Sbjct: 1437 DRKCKDGLYQALKETHPHLIMEL 1459
Score = 28.5 bits (62), Expect = 3.1
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 12 LENLTAEELKKFKLKLLS-VPLREGYGRIPRGALLSMDALDLTDKLVSFYLETYGAELTA 70
LE L EELK+F+L L + R G P +++ LV+ Y E +L
Sbjct: 13 LEFLKKEELKEFQLLLANKAHSRSSSGETP-AQPEKTSGMEVASYLVAQYGEQRAWDLAL 71
Query: 71 NVLRDMGLQEMAGQLQ 86
+ MGL+ + Q Q
Sbjct: 72 HTWEQMGLRSLCAQAQ 87
>gi|4557743 Mediterranean fever protein [Homo sapiens]
Length = 781
Score = 51.6 bits (122), Expect = 3e-07
Identities = 28/86 (32%), Positives = 46/86 (53%)
Query: 6 DAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFYLETYG 65
D +L LE L + +KFK KL + +++ + RIPR + + + LV++Y E Y
Sbjct: 7 DHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARPVKMATLLVTYYGEEYA 66
Query: 66 AELTANVLRDMGLQEMAGQLQAATHQ 91
+LT VLR + + +A +L A Q
Sbjct: 67 VQLTLQVLRAINQRLLAEELHRAAIQ 92
>gi|21264320 NLR family, pyrin domain containing 6 [Homo sapiens]
Length = 892
Score = 48.9 bits (115), Expect = 2e-06
Identities = 35/91 (38%), Positives = 49/91 (53%), Gaps = 4/91 (4%)
Query: 4 ARDAILDALENLTAEELKKFKLKLLSVPLREGYGR-IPRGALLSMDALDLTDKLVSFYLE 62
AR+ +L ALE L+ E+LK+F+ KL V GR IP G L DA+DL ++L FY
Sbjct: 18 ARELLLAALEELSQEQLKRFRHKLRDVGPD---GRSIPWGRLERADAVDLAEQLAQFYGP 74
Query: 63 TYGAELTANVLRDMGLQEMAGQLQAATHQGL 93
E+ L+ +++A QLQ Q L
Sbjct: 75 EPALEVARKTLKRADARDVAAQLQERRLQRL 105
>gi|28827807 NLR family, pyrin domain containing 10 [Homo sapiens]
Length = 655
Score = 46.6 bits (109), Expect = 1e-05
Identities = 31/92 (33%), Positives = 47/92 (51%), Gaps = 3/92 (3%)
Query: 3 RARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFYLE 62
+ R+A+L AL +L + KK K L + L EG + RG L + +DL + L+S Y E
Sbjct: 8 KPREALLWALSDLEENDFKKLKFYLRDMTLSEGQPPLARGELEGLIPVDLAELLISKYGE 67
Query: 63 TYGAELTANVLRDMGLQEMAGQLQAATHQGLH 94
++ L+ M L E+ QL +H LH
Sbjct: 68 KEAVKVVLKGLKVMNLLELVDQL---SHICLH 96
>gi|187937176 NACHT, leucine rich repeat and PYD containing 7
isoform 3 [Homo sapiens]
Length = 1037
Score = 40.0 bits (92), Expect = 0.001
Identities = 24/76 (31%), Positives = 36/76 (47%)
Query: 12 LENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFYLETYGAELTAN 71
LE L +ELK FK L + PL + + P + D L + LV+ E + T N
Sbjct: 14 LEQLNEDELKSFKSLLWAFPLEDVLQKTPWSEVEEADGKKLAEILVNTSSENWIRNATVN 73
Query: 72 VLRDMGLQEMAGQLQA 87
+L +M L E+ +A
Sbjct: 74 ILEEMNLTELCKMAKA 89
>gi|75709196 NACHT, leucine rich repeat and PYD containing 7
isoform 2 [Homo sapiens]
Length = 980
Score = 40.0 bits (92), Expect = 0.001
Identities = 24/76 (31%), Positives = 36/76 (47%)
Query: 12 LENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFYLETYGAELTAN 71
LE L +ELK FK L + PL + + P + D L + LV+ E + T N
Sbjct: 14 LEQLNEDELKSFKSLLWAFPLEDVLQKTPWSEVEEADGKKLAEILVNTSSENWIRNATVN 73
Query: 72 VLRDMGLQEMAGQLQA 87
+L +M L E+ +A
Sbjct: 74 ILEEMNLTELCKMAKA 89
>gi|46049100 NACHT, leucine rich repeat and PYD containing 7
isoform 1 [Homo sapiens]
Length = 1009
Score = 40.0 bits (92), Expect = 0.001
Identities = 24/76 (31%), Positives = 36/76 (47%)
Query: 12 LENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFYLETYGAELTAN 71
LE L +ELK FK L + PL + + P + D L + LV+ E + T N
Sbjct: 14 LEQLNEDELKSFKSLLWAFPLEDVLQKTPWSEVEEADGKKLAEILVNTSSENWIRNATVN 73
Query: 72 VLRDMGLQEMAGQLQA 87
+L +M L E+ +A
Sbjct: 74 ILEEMNLTELCKMAKA 89
>gi|7662404 caspase recruitment domain family, member 8 [Homo
sapiens]
Length = 431
Score = 38.9 bits (89), Expect = 0.002
Identities = 37/156 (23%), Positives = 68/156 (43%), Gaps = 9/156 (5%)
Query: 21 KKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFYLETYGAELTANVLRDMGLQE 80
K+ KL S + + + G + L++T+K +G + ++ + LQ
Sbjct: 281 KELKLSYRSPGEIQHFSKFYAGQMKEPIQLEITEK-------RHGTLVWDTEVKPVDLQL 333
Query: 81 MAGQLQAATHQGLHFIDQHRAALIARVTNVEWLLDALY-GKVLTDEQYQAVRAEPTNPSK 139
+A G F+ ++ L AR+ +++ +LD L +VLT+ + + V E T SK
Sbjct: 334 VAASAPPP-FSGAAFVKENHRQLQARMGDLKGVLDDLQDNEVLTENEKELVEQEKTRQSK 392
Query: 140 MRKLFSFTPAWNWTCKDLLLQALRESQSYLVEDLER 175
L S D+L +++ E YLV L +
Sbjct: 393 NEALLSMVEKKGDLALDVLFRSISERDPYLVSYLRQ 428
>gi|119395764 NLR family, pyrin domain containing 3 isoform a
[Homo sapiens]
Length = 1036
Score = 35.4 bits (80), Expect = 0.026
Identities = 20/59 (33%), Positives = 30/59 (50%)
Query: 1 MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSF 59
M R + LE+L +LKKFK+ L P ++G +PRG D +DL ++ F
Sbjct: 3 MASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDF 61
>gi|188536116 NLR family, pyrin domain containing 3 isoform c
[Homo sapiens]
Length = 979
Score = 35.4 bits (80), Expect = 0.026
Identities = 20/59 (33%), Positives = 30/59 (50%)
Query: 1 MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSF 59
M R + LE+L +LKKFK+ L P ++G +PRG D +DL ++ F
Sbjct: 3 MASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDF 61
>gi|188536002 NLR family, pyrin domain containing 3 isoform d
[Homo sapiens]
Length = 979
Score = 35.4 bits (80), Expect = 0.026
Identities = 20/59 (33%), Positives = 30/59 (50%)
Query: 1 MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSF 59
M R + LE+L +LKKFK+ L P ++G +PRG D +DL ++ F
Sbjct: 3 MASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDF 61
>gi|34878693 NLR family, pyrin domain containing 3 isoform a [Homo
sapiens]
Length = 1036
Score = 35.4 bits (80), Expect = 0.026
Identities = 20/59 (33%), Positives = 30/59 (50%)
Query: 1 MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSF 59
M R + LE+L +LKKFK+ L P ++G +PRG D +DL ++ F
Sbjct: 3 MASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDF 61
>gi|34878690 NLR family, pyrin domain containing 3 isoform b [Homo
sapiens]
Length = 922
Score = 35.4 bits (80), Expect = 0.026
Identities = 20/59 (33%), Positives = 30/59 (50%)
Query: 1 MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSF 59
M R + LE+L +LKKFK+ L P ++G +PRG D +DL ++ F
Sbjct: 3 MASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDF 61
>gi|21955154 NLR family, pyrin domain containing 12 isoform 2
[Homo sapiens]
Length = 1061
Score = 32.7 bits (73), Expect = 0.17
Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Query: 12 LENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFY 60
LE L A ELKKFKL L G G+IP G++ L++ L++ +
Sbjct: 17 LEELEAVELKKFKL-YLGTATELGEGKIPWGSMEKAGPLEMAQLLITHF 64
>gi|5174617 nucleotide-binding oligomerization domain containing 1
[Homo sapiens]
Length = 953
Score = 32.3 bits (72), Expect = 0.22
Identities = 21/93 (22%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Query: 73 LRDMGLQEMAGQLQAATHQGLHFIDQHRAALIARVTNVEWLLDALY-GKVLTDEQYQAVR 131
+ + G EM + + +H + + +R L+ + N + L+D L + E + V
Sbjct: 1 MEEQGHSEME-IIPSESHPHIQLLKSNRELLVTHIRNTQCLVDNLLKNDYFSAEDAEIVC 59
Query: 132 AEPTNPSKMRKLFSFTPAWNWTCKDLLLQALRE 164
A PT P K+RK+ + + L L++
Sbjct: 60 ACPTQPDKVRKILDLVQSKGEEVSEFFLYLLQQ 92
>gi|4506537 receptor-interacting serine-threonine kinase 2 [Homo
sapiens]
Length = 540
Score = 29.6 bits (65), Expect = 1.4
Identities = 16/54 (29%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 114 LDALYGK-VLTDEQYQAVRAEPTNPSKMRKLFSFTPAWNWTCKDLLLQALRESQ 166
LDAL + ++ E Y+ V +PT SK+R+L T +++Q L++++
Sbjct: 460 LDALLSRDLIMKEDYELVSTKPTRTSKVRQLLDTTDIQGEEFAKVIVQKLKDNK 513
>gi|194018482 NLR family, pyrin domain containing 4 [Homo sapiens]
Length = 994
Score = 29.6 bits (65), Expect = 1.4
Identities = 18/70 (25%), Positives = 32/70 (45%)
Query: 12 LENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFYLETYGAELTAN 71
LE L EE +KFK L + L+ +IP + +L + L+ Y E +T
Sbjct: 15 LEELKKEEFRKFKEHLKQMTLQLELKQIPWTEVKKASREELANLLIKHYEEQQAWNITLR 74
Query: 72 VLRDMGLQEM 81
+ + M +++
Sbjct: 75 IFQKMDRKDL 84
>gi|118722351 growth hormone regulated TBC protein 1 [Homo sapiens]
Length = 336
Score = 29.6 bits (65), Expect = 1.4
Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 8/57 (14%)
Query: 91 QGLHFIDQHRAALIARVTNVE----WLLDALYGKVLTDEQYQAVRAEPTNPSKMRKL 143
QG++FI A + +TN E WLLDAL G++L D A+ T+ + +L
Sbjct: 155 QGMNFI----AGYLILITNNEEESFWLLDALVGRILPDYYSPAMLGLKTDQEVLGEL 207
>gi|74271814 NLR family, pyrin domain containing 1 isoform 5 [Homo
sapiens]
Length = 1375
Score = 28.5 bits (62), Expect = 3.1
Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 12 LENLTAEELKKFKLKLLS-VPLREGYGRIPRGALLSMDALDLTDKLVSFYLETYGAELTA 70
LE L EELK+F+L L + R G P +++ LV+ Y E +L
Sbjct: 13 LEFLKKEELKEFQLLLANKAHSRSSSGETP-AQPEKTSGMEVASYLVAQYGEQRAWDLAL 71
Query: 71 NVLRDMGLQEMAGQLQ 86
+ MGL+ + Q Q
Sbjct: 72 HTWEQMGLRSLCAQAQ 87
>gi|8923473 NLR family, pyrin domain containing 2 [Homo sapiens]
Length = 1062
Score = 26.9 bits (58), Expect = 9.2
Identities = 15/59 (25%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 12 LENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFYLETYGAELTA 70
LE L+ +EL KFK + + L +IP + D L + +++ + ++Y E+ +
Sbjct: 15 LEQLSQDELSKFKYLITTFSLAHELQKIPHKEVDKADGKQLVE-ILTTHCDSYWVEMAS 72
>gi|4505419 nucleolar protein 3 [Homo sapiens]
Length = 208
Score = 26.9 bits (58), Expect = 9.2
Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
Query: 96 IDQHRAALIARV-TNVEWLLDALYGK-VLTDEQYQAVRAEPTNPSKMRKLFSFTPA-WNW 152
ID+ R L+ + + LLDAL + VLT +Y+A+ A P ++R+L
Sbjct: 12 IDRERKRLVETLQADSGLLLDALLARGVLTGPEYEALDALPDAERRVRRLLLLVQGKGEA 71
Query: 153 TCKDLLLQALR 163
C++LL A R
Sbjct: 72 ACQELLRCAQR 82
>gi|66529203 hypothetical protein LOC57714 [Homo sapiens]
Length = 1063
Score = 26.9 bits (58), Expect = 9.2
Identities = 20/77 (25%), Positives = 34/77 (44%), Gaps = 6/77 (7%)
Query: 48 DALDLTDKLVSFY-LETYGAELTANVLRDMGLQEMAGQLQAATHQGLHFIDQHRAALIAR 106
+A+ + KL+ FY L AE+ ++R + L + AGQ + + + Q A R
Sbjct: 853 EAICSSTKLLKFYELPALSAEIVCRMIRLLSLVDSAGQRDETGNNSVQTVFQGTLAATKR 912
Query: 107 VTNVEWLLDALYGKVLT 123
WL + +LT
Sbjct: 913 -----WLREVFTKNMLT 924
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,630,582
Number of Sequences: 37866
Number of extensions: 203778
Number of successful extensions: 546
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 517
Number of HSP's gapped (non-prelim): 33
length of query: 176
length of database: 18,247,518
effective HSP length: 95
effective length of query: 81
effective length of database: 14,650,248
effective search space: 1186670088
effective search space used: 1186670088
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.