Guide to the Human Genome
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Search of human proteins with 22027620

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22027620 TNF receptor-associated factor 3 isoform 2 [Homo
sapiens]
         (543 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22027620 TNF receptor-associated factor 3 isoform 2 [Homo sap...  1110   0.0  
gi|22027616 TNF receptor-associated factor 3 isoform 1 [Homo sap...  1096   0.0  
gi|22027618 TNF receptor-associated factor 3 isoform 1 [Homo sap...  1096   0.0  
gi|22027627 TNF receptor-associated factor 5 [Homo sapiens]           420   e-117
gi|77404348 TNF receptor-associated factor 5 [Homo sapiens]           420   e-117
gi|11321603 TNF receptor-associated factor 5 [Homo sapiens]           420   e-117
gi|22027612 TNF receptor-associated factor 2 [Homo sapiens]           275   1e-73
gi|5032193 TNF receptor-associated factor 1 [Homo sapiens]            212   8e-55
gi|22027630 TNF receptor-associated factor 6 [Homo sapiens]           172   9e-43
gi|4759254 TNF receptor-associated factor 6 [Homo sapiens]            172   9e-43
gi|22027622 TNF receptor-associated factor 4 [Homo sapiens]           128   1e-29
gi|57529737 PDZ domain containing ring finger 3 [Homo sapiens]         72   1e-12
gi|87241872 ring finger protein 151 [Homo sapiens]                     71   3e-12
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]               60   4e-09
gi|34577114 cytomatrix protein p110 [Homo sapiens]                     54   3e-07
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    52   1e-06
gi|37595555 ring finger protein 125 [Homo sapiens]                     52   1e-06
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    51   3e-06
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap...    48   3e-05
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]    48   3e-05
gi|45594312 TNF receptor-associated factor 7 [Homo sapiens]            48   3e-05
gi|19920317 cytoskeleton-associated protein 4 [Homo sapiens]           47   4e-05
gi|30520320 ring finger protein 166 [Homo sapiens]                     47   4e-05
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]                   46   8e-05
gi|21361539 ring finger protein 138 isoform 1 [Homo sapiens]           46   1e-04
gi|124517695 ankyrin repeat domain 36B [Homo sapiens]                  45   1e-04
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]        45   2e-04
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    45   2e-04
gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]           45   2e-04
gi|190194355 p90 autoantigen [Homo sapiens]                            44   3e-04

>gi|22027620 TNF receptor-associated factor 3 isoform 2 [Homo
           sapiens]
          Length = 543

 Score = 1110 bits (2870), Expect = 0.0
 Identities = 543/543 (100%), Positives = 543/543 (100%)

Query: 1   MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVL 60
           MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVL
Sbjct: 1   MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVL 60

Query: 61  CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE 120
           CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE
Sbjct: 61  CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE 120

Query: 121 SRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC 180
           SRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC
Sbjct: 121 SRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC 180

Query: 181 KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKE 240
           KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKE
Sbjct: 181 KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKE 240

Query: 241 WSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDS 300
           WSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDS
Sbjct: 241 WSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDS 300

Query: 301 QAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQL 360
           QAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQL
Sbjct: 301 QAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQL 360

Query: 361 SRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPF 420
           SRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPF
Sbjct: 361 SRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPF 420

Query: 421 YTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSR 480
           YTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSR
Sbjct: 421 YTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSR 480

Query: 481 RHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDTSDL 540
           RHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDTSDL
Sbjct: 481 RHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDTSDL 540

Query: 541 PDP 543
           PDP
Sbjct: 541 PDP 543


>gi|22027616 TNF receptor-associated factor 3 isoform 1 [Homo
           sapiens]
          Length = 568

 Score = 1096 bits (2834), Expect = 0.0
 Identities = 543/568 (95%), Positives = 543/568 (95%), Gaps = 25/568 (4%)

Query: 1   MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVL 60
           MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVL
Sbjct: 1   MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVL 60

Query: 61  CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE 120
           CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE
Sbjct: 61  CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE 120

Query: 121 SRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC 180
           SRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC
Sbjct: 121 SRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC 180

Query: 181 KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSE----------------------- 217
           KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSE                       
Sbjct: 181 KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCV 240

Query: 218 --GTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI 275
             GTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI
Sbjct: 241 FQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI 300

Query: 276 EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR 335
           EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR
Sbjct: 301 EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR 360

Query: 336 VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW 395
           VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW
Sbjct: 361 VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW 420

Query: 396 KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRG 455
           KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRG
Sbjct: 421 KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRG 480

Query: 456 EYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQ 515
           EYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQ
Sbjct: 481 EYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQ 540

Query: 516 TVLENGTYIKDDTIFIKVIVDTSDLPDP 543
           TVLENGTYIKDDTIFIKVIVDTSDLPDP
Sbjct: 541 TVLENGTYIKDDTIFIKVIVDTSDLPDP 568


>gi|22027618 TNF receptor-associated factor 3 isoform 1 [Homo
           sapiens]
          Length = 568

 Score = 1096 bits (2834), Expect = 0.0
 Identities = 543/568 (95%), Positives = 543/568 (95%), Gaps = 25/568 (4%)

Query: 1   MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVL 60
           MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVL
Sbjct: 1   MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVL 60

Query: 61  CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE 120
           CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE
Sbjct: 61  CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE 120

Query: 121 SRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC 180
           SRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC
Sbjct: 121 SRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC 180

Query: 181 KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSE----------------------- 217
           KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSE                       
Sbjct: 181 KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCV 240

Query: 218 --GTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI 275
             GTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI
Sbjct: 241 FQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI 300

Query: 276 EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR 335
           EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR
Sbjct: 301 EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR 360

Query: 336 VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW 395
           VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW
Sbjct: 361 VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW 420

Query: 396 KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRG 455
           KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRG
Sbjct: 421 KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRG 480

Query: 456 EYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQ 515
           EYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQ
Sbjct: 481 EYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQ 540

Query: 516 TVLENGTYIKDDTIFIKVIVDTSDLPDP 543
           TVLENGTYIKDDTIFIKVIVDTSDLPDP
Sbjct: 541 TVLENGTYIKDDTIFIKVIVDTSDLPDP 568


>gi|22027627 TNF receptor-associated factor 5 [Homo sapiens]
          Length = 557

 Score =  420 bits (1080), Expect = e-117
 Identities = 222/552 (40%), Positives = 342/552 (61%), Gaps = 46/552 (8%)

Query: 25  RSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSS 84
           +++G  + +  +   + +FV+ +E++YKC  CH VL +P QT CGHRFC+ C+ +L   +
Sbjct: 17  QNSGNSISLDFEPSIEYQFVERLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILSLRELN 76

Query: 85  S-PKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHF 143
           + P C   +E I   +VFKDNCCKRE+L L +YC N + GC  +++LG    HL+  C F
Sbjct: 77  TVPICPVDKEVIKSQEVFKDNCCKREVLNLYVYCSN-APGCNAKVILGRYQDHLQQ-CLF 134

Query: 144 EELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVS 203
           + + C    C+E VLRKDL++H+  +C++R+  C +CK  V +I LQ HE+  CP   V 
Sbjct: 135 QPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCKKDVVVINLQNHEENLCPEYPVF 194

Query: 204 CPHKCSVQTLLRSE-------------------------GTNQQIKAHEASSAVQHVNLL 238
           CP+ C+ + +L++E                            + ++ HE S+  +H+ L+
Sbjct: 195 CPNNCA-KIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLV 253

Query: 239 KEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVI 298
            E +  LE+++S L     +K   IQ L   I   E E ++  ++   N S + ++Q V 
Sbjct: 254 LEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQ-VF 312

Query: 299 DSQAEKLKELDKEIRPF------RQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARN 352
            S  +K   L+ ++         +QN  +   +  +V++++ ++T LE+ D+        
Sbjct: 313 ASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQ-------R 365

Query: 353 TGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKT 412
             +LE + ++HD  +++H  +L+  + RF++LE   YNG LIWK+ DYK +K+EAV G T
Sbjct: 366 LAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHT 425

Query: 413 LSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLM 472
           +S++SQ FYT   GY++CAR YLNGDG G+G+HLSL+FV+MRGE+D+LL WPF+Q+VTLM
Sbjct: 426 VSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLM 485

Query: 473 LMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLEN--GTYIKDDTIF 530
           L+DQ S ++++ + FKPDPNSSSFK+P GEMNIASGCP FVA +VLEN    YIKDDT+F
Sbjct: 486 LLDQ-SGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLF 544

Query: 531 IKVIVDTSDLPD 542
           +KV VD +DL D
Sbjct: 545 LKVAVDLTDLED 556


>gi|77404348 TNF receptor-associated factor 5 [Homo sapiens]
          Length = 557

 Score =  420 bits (1080), Expect = e-117
 Identities = 222/552 (40%), Positives = 342/552 (61%), Gaps = 46/552 (8%)

Query: 25  RSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSS 84
           +++G  + +  +   + +FV+ +E++YKC  CH VL +P QT CGHRFC+ C+ +L   +
Sbjct: 17  QNSGNSISLDFEPSIEYQFVERLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILSLRELN 76

Query: 85  S-PKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHF 143
           + P C   +E I   +VFKDNCCKRE+L L +YC N + GC  +++LG    HL+  C F
Sbjct: 77  TVPICPVDKEVIKSQEVFKDNCCKREVLNLYVYCSN-APGCNAKVILGRYQDHLQQ-CLF 134

Query: 144 EELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVS 203
           + + C    C+E VLRKDL++H+  +C++R+  C +CK  V +I LQ HE+  CP   V 
Sbjct: 135 QPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCKKDVVVINLQNHEENLCPEYPVF 194

Query: 204 CPHKCSVQTLLRSE-------------------------GTNQQIKAHEASSAVQHVNLL 238
           CP+ C+ + +L++E                            + ++ HE S+  +H+ L+
Sbjct: 195 CPNNCA-KIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLV 253

Query: 239 KEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVI 298
            E +  LE+++S L     +K   IQ L   I   E E ++  ++   N S + ++Q V 
Sbjct: 254 LEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQ-VF 312

Query: 299 DSQAEKLKELDKEIRPF------RQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARN 352
            S  +K   L+ ++         +QN  +   +  +V++++ ++T LE+ D+        
Sbjct: 313 ASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQ-------R 365

Query: 353 TGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKT 412
             +LE + ++HD  +++H  +L+  + RF++LE   YNG LIWK+ DYK +K+EAV G T
Sbjct: 366 LAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHT 425

Query: 413 LSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLM 472
           +S++SQ FYT   GY++CAR YLNGDG G+G+HLSL+FV+MRGE+D+LL WPF+Q+VTLM
Sbjct: 426 VSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLM 485

Query: 473 LMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLEN--GTYIKDDTIF 530
           L+DQ S ++++ + FKPDPNSSSFK+P GEMNIASGCP FVA +VLEN    YIKDDT+F
Sbjct: 486 LLDQ-SGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLF 544

Query: 531 IKVIVDTSDLPD 542
           +KV VD +DL D
Sbjct: 545 LKVAVDLTDLED 556


>gi|11321603 TNF receptor-associated factor 5 [Homo sapiens]
          Length = 557

 Score =  420 bits (1080), Expect = e-117
 Identities = 222/552 (40%), Positives = 342/552 (61%), Gaps = 46/552 (8%)

Query: 25  RSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSS 84
           +++G  + +  +   + +FV+ +E++YKC  CH VL +P QT CGHRFC+ C+ +L   +
Sbjct: 17  QNSGNSISLDFEPSIEYQFVERLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILSLRELN 76

Query: 85  S-PKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHF 143
           + P C   +E I   +VFKDNCCKRE+L L +YC N + GC  +++LG    HL+  C F
Sbjct: 77  TVPICPVDKEVIKSQEVFKDNCCKREVLNLYVYCSN-APGCNAKVILGRYQDHLQQ-CLF 134

Query: 144 EELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVS 203
           + + C    C+E VLRKDL++H+  +C++R+  C +CK  V +I LQ HE+  CP   V 
Sbjct: 135 QPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCKKDVVVINLQNHEENLCPEYPVF 194

Query: 204 CPHKCSVQTLLRSE-------------------------GTNQQIKAHEASSAVQHVNLL 238
           CP+ C+ + +L++E                            + ++ HE S+  +H+ L+
Sbjct: 195 CPNNCA-KIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLV 253

Query: 239 KEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVI 298
            E +  LE+++S L     +K   IQ L   I   E E ++  ++   N S + ++Q V 
Sbjct: 254 LEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQ-VF 312

Query: 299 DSQAEKLKELDKEIRPF------RQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARN 352
            S  +K   L+ ++         +QN  +   +  +V++++ ++T LE+ D+        
Sbjct: 313 ASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQ-------R 365

Query: 353 TGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKT 412
             +LE + ++HD  +++H  +L+  + RF++LE   YNG LIWK+ DYK +K+EAV G T
Sbjct: 366 LAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHT 425

Query: 413 LSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLM 472
           +S++SQ FYT   GY++CAR YLNGDG G+G+HLSL+FV+MRGE+D+LL WPF+Q+VTLM
Sbjct: 426 VSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLM 485

Query: 473 LMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLEN--GTYIKDDTIF 530
           L+DQ S ++++ + FKPDPNSSSFK+P GEMNIASGCP FVA +VLEN    YIKDDT+F
Sbjct: 486 LLDQ-SGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLF 544

Query: 531 IKVIVDTSDLPD 542
           +KV VD +DL D
Sbjct: 545 LKVAVDLTDLED 556


>gi|22027612 TNF receptor-associated factor 2 [Homo sapiens]
          Length = 501

 Score =  275 bits (702), Expect = 1e-73
 Identities = 179/526 (34%), Positives = 277/526 (52%), Gaps = 61/526 (11%)

Query: 36  QGGYKEKFVKT-VEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTAC-QE 93
           Q G+ +  + T +E KY C  C  VL  P Q +CGHR+C  C+A++LSS    C AC  E
Sbjct: 16  QPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHE 75

Query: 94  SIVKDKV--------FKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEE 145
            I ++ +        F DN  +RE+ +L   C ++  GC  +  L          CH   
Sbjct: 76  GIYEEGISILESSSAFPDNAARREVESLPAVCPSD--GCTWKGTLKEY-----ESCHEGR 128

Query: 146 LPCVR---PDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVV 202
            P +    P CK  V   +   H+E  C  R  +C HC++      ++ H +  CP   +
Sbjct: 129 CPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHEV-CPKFPL 187

Query: 203 SCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKS 262
           +C   C  + + R     ++ + H  +     V         LE         +VE  K 
Sbjct: 188 TCDG-CGKKKIPR-----EKFQDHVKTCGKCRVPCRFHAIGCLE---------TVEGEKQ 232

Query: 263 IQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEA 322
                      E E++  +E L    S +L  + ++  Q+    EL +      ++ E+ 
Sbjct: 233 Q----------EHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRC----ESLEKK 278

Query: 323 DSMKSSVESLQNRVTELESVDKSAGQVARNTGL-------LESQLSRHDQMLSVHDIRLA 375
            +   ++  + NR  E+E V  +A   +R   L       L S++ + ++ + + D+ +A
Sbjct: 279 TATFENIVCVLNR--EVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMA 336

Query: 376 DMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYL 435
           D++ +   +E ++Y+GV IWKI D+ R++QEAV G+  +++S  FYT  +GYKMC R+YL
Sbjct: 337 DLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYL 396

Query: 436 NGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSS 495
           NGDG G+GTHLSLFFV+M+G  DALL WPF QKVTLML+DQ ++R H+ DAF+PD  SSS
Sbjct: 397 NGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQ-NNREHVIDAFRPDVTSSS 455

Query: 496 FKKPTGEMNIASGCPVFVAQTVLE-NGTYIKDDTIFIKVIVDTSDL 540
           F++P  +MNIASGCP+F   + +E   +Y++DD IFIK IVD + L
Sbjct: 456 FQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL 501


>gi|5032193 TNF receptor-associated factor 1 [Homo sapiens]
          Length = 416

 Score =  212 bits (539), Expect = 8e-55
 Identities = 134/365 (36%), Positives = 196/365 (53%), Gaps = 60/365 (16%)

Query: 197 CPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLL----KEWSNSL-----EK 247
           CP   V C  K          G+ Q ++ HE +S   H+NLL    K+W   L       
Sbjct: 88  CPFAGVGCSFK----------GSPQSVQEHEVTSQTSHLNLLLGFMKQWKARLGCGLESG 137

Query: 248 KVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKE 307
            ++L QN S   +  +Q+        E++  R        E  + H  +      + L E
Sbjct: 138 PMALEQNLS---DLQLQAAVEVAGDLEVDCYRAPCSESQEELALQHFMK-----EKLLAE 189

Query: 308 LDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRH---- 363
           L+ ++R F            ++ ++ N+  E       A  +A  T + +SQL R     
Sbjct: 190 LEGKLRVFE-----------NIVAVLNKEVE-------ASHLALATSIHQSQLDRERILS 231

Query: 364 --------DQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSL 415
                    Q L+  D  L  ++   +++E AS++G  +WKI +  RR  E+  G+T+SL
Sbjct: 232 LEQRVVELQQTLAQKDQALGKLEQSLRLMEEASFDGTFLWKITNVTRRCHESACGRTVSL 291

Query: 416 YSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMD 475
           +S  FYT  +GYK+C R+YLNGDG GK THLSLF VIMRGEYDALLPWPF+ KVT ML+D
Sbjct: 292 FSPAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLD 351

Query: 476 QGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLEN--GTYIKDDTIFIKV 533
           Q ++R H  DAF+PD +S+SF++P  E N+ASGCP+F   + L++    Y+KDDT+F+K 
Sbjct: 352 Q-NNREHAIDAFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKC 410

Query: 534 IVDTS 538
           IV+TS
Sbjct: 411 IVETS 415


>gi|22027630 TNF receptor-associated factor 6 [Homo sapiens]
          Length = 522

 Score =  172 bits (435), Expect = 9e-43
 Identities = 136/515 (26%), Positives = 229/515 (44%), Gaps = 71/515 (13%)

Query: 32  FVPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTAC 91
           F+ E  GY  +F   +E KY+C  C + L    QT CGHRFC++C+   +  +  KC   
Sbjct: 49  FMEEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVD 108

Query: 92  QESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRP 151
            E ++++++F DN  KREIL+L + C NE  GC  ++ L HL  H  + C F  + C  P
Sbjct: 109 NEILLENQLFPDNFAKREILSLMVKCPNE--GCLHKMELRHLEDHQAH-CEFALMDC--P 163

Query: 152 DCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQ 211
            C+    +  +  H+ K C  R+ +C +C + +     + H D +CP   V C       
Sbjct: 164 QCQRPFQKFHINIHILKDCPRRQVSCDNCAASMAFEDKEIH-DQNCPLANVIC------- 215

Query: 212 TLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQI- 270
                                       E+ N++      L  E +  +  +      I 
Sbjct: 216 ----------------------------EYCNTI------LIREQMPNHYDLDCPTAPIP 241

Query: 271 CSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKEL--DKEIRPFRQNWEEADSMKSS 328
           C+F       ++M RN+ ++  HLQ    S    L +      + P      E  + + +
Sbjct: 242 CTFST-FGCHEKMQRNHLAR--HLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQET 298

Query: 329 VESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQV--LET 386
           +  L+ R+   +       Q+   T  +E+Q       + V +++     L  +V  +E 
Sbjct: 299 IHQLEGRLVRQDH------QIRELTAKMETQ------SMYVSELKRTIRTLEDKVAEIEA 346

Query: 387 ASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLN-GDGMGKGTH 445
              NG+ IWKI ++    +     K + ++S  FYTG  GYK+C R++L          +
Sbjct: 347 QQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANY 406

Query: 446 LSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSS--RRHLGDAFKPDPNSSSFKKPTGEM 503
           +SLF   M+GEYD+ LPWPF+  + L ++DQ  +  R++  +     P   +F++PT   
Sbjct: 407 ISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPR 466

Query: 504 NIAS-GCPVFVAQTVLENGTYIKDDTIFIKVIVDT 537
           N    G   F+    L   T+IKDDT+ ++  V T
Sbjct: 467 NPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVST 501


>gi|4759254 TNF receptor-associated factor 6 [Homo sapiens]
          Length = 522

 Score =  172 bits (435), Expect = 9e-43
 Identities = 136/515 (26%), Positives = 229/515 (44%), Gaps = 71/515 (13%)

Query: 32  FVPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTAC 91
           F+ E  GY  +F   +E KY+C  C + L    QT CGHRFC++C+   +  +  KC   
Sbjct: 49  FMEEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVD 108

Query: 92  QESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRP 151
            E ++++++F DN  KREIL+L + C NE  GC  ++ L HL  H  + C F  + C  P
Sbjct: 109 NEILLENQLFPDNFAKREILSLMVKCPNE--GCLHKMELRHLEDHQAH-CEFALMDC--P 163

Query: 152 DCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQ 211
            C+    +  +  H+ K C  R+ +C +C + +     + H D +CP   V C       
Sbjct: 164 QCQRPFQKFHINIHILKDCPRRQVSCDNCAASMAFEDKEIH-DQNCPLANVIC------- 215

Query: 212 TLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQI- 270
                                       E+ N++      L  E +  +  +      I 
Sbjct: 216 ----------------------------EYCNTI------LIREQMPNHYDLDCPTAPIP 241

Query: 271 CSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKEL--DKEIRPFRQNWEEADSMKSS 328
           C+F       ++M RN+ ++  HLQ    S    L +      + P      E  + + +
Sbjct: 242 CTFST-FGCHEKMQRNHLAR--HLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQET 298

Query: 329 VESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQV--LET 386
           +  L+ R+   +       Q+   T  +E+Q       + V +++     L  +V  +E 
Sbjct: 299 IHQLEGRLVRQDH------QIRELTAKMETQ------SMYVSELKRTIRTLEDKVAEIEA 346

Query: 387 ASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLN-GDGMGKGTH 445
              NG+ IWKI ++    +     K + ++S  FYTG  GYK+C R++L          +
Sbjct: 347 QQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANY 406

Query: 446 LSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSS--RRHLGDAFKPDPNSSSFKKPTGEM 503
           +SLF   M+GEYD+ LPWPF+  + L ++DQ  +  R++  +     P   +F++PT   
Sbjct: 407 ISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPR 466

Query: 504 NIAS-GCPVFVAQTVLENGTYIKDDTIFIKVIVDT 537
           N    G   F+    L   T+IKDDT+ ++  V T
Sbjct: 467 NPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVST 501


>gi|22027622 TNF receptor-associated factor 4 [Homo sapiens]
          Length = 470

 Score =  128 bits (322), Expect = 1e-29
 Identities = 63/157 (40%), Positives = 93/157 (59%), Gaps = 10/157 (6%)

Query: 390 NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLF 449
           +GVLIWKI  Y RR QEA     L  +S  FYT  +GYK+    +LNG+G G+GTHLSL+
Sbjct: 307 DGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSLY 366

Query: 450 FVIMRGEYDALLPWPFKQKVTLMLMDQG----SSRRHLGDAFKPDPNSSSFKKP------ 499
             ++ G +D LL WPF ++VT  L+DQ     +  +H+ + F PDPN  +F+KP      
Sbjct: 367 IRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGS 426

Query: 500 TGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVD 536
             E ++  G P F++   +    Y++DD +FI+  V+
Sbjct: 427 LDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRAAVE 463



 Score = 94.0 bits (232), Expect = 3e-19
 Identities = 57/179 (31%), Positives = 82/179 (45%), Gaps = 4/179 (2%)

Query: 38  GYKEKFVKTVEDKYKCEKCHLVLCSPKQTE-CGHRFCESCMAALLSSSSPKCTACQESIV 96
           G+  KF++  + +  C  C   +  P Q   CGHRFC++C+   LS    KC   Q  + 
Sbjct: 3   GFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLD 62

Query: 97  KDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEK 156
             K++ D   + ++L L I C +   GC     L HL  HL N C F  +PC    C  K
Sbjct: 63  YAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHL-NTCSFNVIPCPN-RCPMK 120

Query: 157 VLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLR 215
           + R+DL  H++  C  R   C  C       A + HE   CP   V C +KC  + + R
Sbjct: 121 LSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGM-CPQESVYCENKCGARMMRR 178


>gi|57529737 PDZ domain containing ring finger 3 [Homo sapiens]
          Length = 1066

 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 42/133 (31%), Positives = 59/133 (44%), Gaps = 1/133 (0%)

Query: 41  EKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKV 100
           ++F   V+   KC  CH VL  P  T CGH FC  C+   +         C+  +   ++
Sbjct: 6   DRFDGDVDPDLKCALCHKVLEDPLTTPCGHVFCAGCVLPWVVQEGSCPARCRGRLSAKEL 65

Query: 101 FKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRK 160
                 KR IL L I C   +RGC   + L  L  HL+  C F    C    C + +LR+
Sbjct: 66  NHVLPLKRLILKLDIKCAYATRGCGRVVKLQQLPEHLER-CDFAPARCRHAGCGQVLLRR 124

Query: 161 DLRDHVEKACKYR 173
           D+  H+  AC  R
Sbjct: 125 DVEAHMRDACDAR 137


>gi|87241872 ring finger protein 151 [Homo sapiens]
          Length = 245

 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 40/142 (28%), Positives = 62/142 (43%), Gaps = 3/142 (2%)

Query: 37  GGYK-EKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTACQESI 95
           GGY    F    +  + C  CH VL  P +  C H FC+ C+   L+     C  C++ +
Sbjct: 3   GGYDLNLFASPPDSNFVCSVCHGVLKRPARLPCSHIFCKKCILRWLARQK-TCPCCRKEV 61

Query: 96  VKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKE 155
            + KV   N  ++ I  L++ C+N   GC     L H   H ++ C FE   C    C  
Sbjct: 62  KRKKVVHMNKLRKTIGRLEVKCKNADAGCIVTCPLAHRKGH-QDSCPFELTACPNEGCTS 120

Query: 156 KVLRKDLRDHVEKACKYREATC 177
           +V R  L +H +   +  +  C
Sbjct: 121 QVPRGTLAEHRQHCQQGSQQRC 142


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 58/248 (23%), Positives = 110/248 (44%), Gaps = 26/248 (10%)

Query: 190  QKHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKV 249
            QKHE++           +     LL+ + T ++    + +   ++ NL +E SN L  +V
Sbjct: 1470 QKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISN-LTNQV 1528

Query: 250  SLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQ-RVIDSQAE---KL 305
                    E  K  + +  +    ++ +E  +  L  NESKILH Q  +++++AE   KL
Sbjct: 1529 REGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKL 1588

Query: 306  KELDKEIRPFRQNWE-EADSMKSSVES------------------LQNRVTELESVDKSA 346
             E D+EI  FR+  +   DS++SS++S                  L     +L   ++  
Sbjct: 1589 SEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQV 1648

Query: 347  GQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQE 406
             +  ++ G L+ Q+   D  + + D    + DL+ QV      N +L  ++ D +  +++
Sbjct: 1649 SEATKSLGQLQIQIK--DLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQ 1706

Query: 407  AVMGKTLS 414
               G+ LS
Sbjct: 1707 TERGRRLS 1714



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 34/155 (21%), Positives = 68/155 (43%), Gaps = 21/155 (13%)

Query: 210  VQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSL-------EKKVSLLQNESVEKNKS 262
            +++L       +++   E   A + +NL    + SL       E  V+ +Q E+ E  + 
Sbjct: 1700 LRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQE 1759

Query: 263  IQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEA 322
             Q+   +     IE     E L+  +  I HL+R  ++  + + +L K +        EA
Sbjct: 1760 CQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRL-------AEA 1812

Query: 323  DSM-----KSSVESLQNRVTELESVDKSAGQVARN 352
            + M     +  ++ L++RV ELE   +  G++ R+
Sbjct: 1813 EQMALMGSRKQIQKLESRVRELEG--ELEGEIRRS 1845


>gi|34577114 cytomatrix protein p110 [Homo sapiens]
          Length = 957

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 45/181 (24%), Positives = 84/181 (46%), Gaps = 22/181 (12%)

Query: 219 TNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESV--------------EKNKSIQ 264
           T  +  +++ S   QH+ +LKE   + E++ ++LQ E                +K K +Q
Sbjct: 455 TKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQ 514

Query: 265 SLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADS 324
            L  +  +   EI   K+ML   E KI  LQ+ I++  E+L++ DK++   +      D 
Sbjct: 515 DLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLK------DR 568

Query: 325 MKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHD--QMLSVHDIRLADMDLRFQ 382
           +KS      N  T L +++++  +  R    L+ Q  R D  ++  +   R  + DL+ +
Sbjct: 569 VKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEK 628

Query: 383 V 383
           V
Sbjct: 629 V 629



 Score = 32.7 bits (73), Expect = 0.87
 Identities = 30/155 (19%), Positives = 67/155 (43%), Gaps = 14/155 (9%)

Query: 232 VQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKI 291
           ++ +   ++ +  L++KV+ LQ E  EK  S+  L     S      ++       +SK+
Sbjct: 612 LEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKR-------DSKL 664

Query: 292 LHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVAR 351
             L+  I+ + E+  +L+ +++    N E+   M            +++ +DK A     
Sbjct: 665 KSLEIAIEQKKEECSKLEAQLKK-AHNIEDDSRMNPEFAD------QIKQLDKEASYYRD 717

Query: 352 NTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLET 386
             G  ++++ R  ++L   +    D D +   LE+
Sbjct: 718 ECGKAQAEVDRLLEILKEVENEKNDKDKKIAELES 752


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 37/200 (18%), Positives = 91/200 (45%), Gaps = 6/200 (3%)

Query: 213 LLRSEGTNQQIKAHEASSAVQHVNLL--KEWSNSLEKKVSLLQNESVEKNKSIQSLHNQI 270
           L  SE +  Q+   E    ++    L  +  +N+L++++   + E  E+ K I+    ++
Sbjct: 236 LAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKM 295

Query: 271 CSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVE 330
              E  +  Q+  +R  E K+   ++ +  Q ++L+E +KE+R  ++  E+ + M+   E
Sbjct: 296 WRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEE 355

Query: 331 SLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYN 390
            +  +  ++   ++   +        E Q+   +Q +   + R+ + D R +  E     
Sbjct: 356 KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMRE 415

Query: 391 GVLIW----KIRDYKRRKQE 406
              +W    K+R+ K+ +++
Sbjct: 416 QEKMWEQVEKMREEKKMQEQ 435



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 22/105 (20%), Positives = 52/105 (49%), Gaps = 6/105 (5%)

Query: 239 KEWSNS--LEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQR 296
           K W     +EKK    + ++ ++ + ++    ++   E ++  ++EM+R  E K+   + 
Sbjct: 559 KMWDQEERMEKKTQEQEKKTWDQEEKMRE-EERMREREKKMREEEEMMREQEEKMQEQEE 617

Query: 297 VIDSQAEKLKELDKEIRPFRQN-WEEADSMKSSVESL--QNRVTE 338
            +  Q EK+ E +++++   +  WE+ + M    E +  Q R+ E
Sbjct: 618 KMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPE 662



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 22/104 (21%), Positives = 51/104 (49%), Gaps = 3/104 (2%)

Query: 246 EKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKL 305
           E+K  L ++E +++ + I     ++   E ++  Q+E +R  E K+   +  +  Q EK+
Sbjct: 772 EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKM 831

Query: 306 -KELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQ 348
             + +K      + W + + M+  ++  + ++ E E  +K  GQ
Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQE--EKMRGQ 873



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 28/156 (17%), Positives = 66/156 (42%), Gaps = 3/156 (1%)

Query: 211 QTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQI 270
           + L   E   +Q K  E    +     +++ +   EKK      E + + +S++    ++
Sbjct: 665 EKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKT--WDQEKMREEESMREREKKM 722

Query: 271 CSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVE 330
              E  +  Q+E ++  E K+   +  +  Q EK+ E ++++   ++  E+ + +    E
Sbjct: 723 REEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEH-E 781

Query: 331 SLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQM 366
            +Q +    E  +K   Q  +  G  E    + ++M
Sbjct: 782 KMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKM 817



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 21/109 (19%), Positives = 49/109 (44%), Gaps = 1/109 (0%)

Query: 246 EKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKL 305
           EKK+   +    E+ + +Q    ++   E ++  Q+E ++  E K+   +  +  Q EK+
Sbjct: 595 EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM 654

Query: 306 KELDKEIRPFRQNWE-EADSMKSSVESLQNRVTELESVDKSAGQVARNT 353
            E  +      + WE E    +  ++  + ++ E E ++K   +  + T
Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKT 703



 Score = 29.6 bits (65), Expect = 7.4
 Identities = 28/163 (17%), Positives = 68/163 (41%), Gaps = 23/163 (14%)

Query: 221 QQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQ 280
           Q+ K  +    +Q    ++E    + ++   ++ +  +  K  +++  Q      E E Q
Sbjct: 435 QEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE-----EKEWQ 489

Query: 281 KEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNW-------------EEADSMKS 327
           ++ L   + K+   Q  +  Q EK+ E +++IR   + W             E+ D M  
Sbjct: 490 QQRLPEQKEKLWE-QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE 548

Query: 328 SVESLQNRVTEL----ESVDKSAGQVARNTGLLESQLSRHDQM 366
             E ++++  ++    E ++K   +  + T   E ++   ++M
Sbjct: 549 QEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERM 591


>gi|37595555 ring finger protein 125 [Homo sapiens]
          Length = 232

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 43/179 (24%), Positives = 69/179 (38%), Gaps = 27/179 (15%)

Query: 21  LHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAAL 80
           L TD     P     +   + +  +     + C  C  VL  P +T CGH FC SC+A  
Sbjct: 5   LSTDSGKSAPASATARALERRRDPELPVTSFDCAVCLEVLHQPVRTRCGHVFCRSCIATS 64

Query: 81  LSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAE---QLMLGHLLVHL 137
           L ++   C  C+  +  + V   +  KR         ++E + CAE    + L  +  H+
Sbjct: 65  LKNNKWTCPYCRAYLPSEGVPATDVAKR--------MKSEYKNCAECDTLVCLSEMRAHI 116

Query: 138 KNDCH--------FEELP-----CVRPDCKEKVLRKDLRDH--VEKACKYREATCSHCK 181
           +  C          +EL      CV P C+ ++    L DH       + R   C  C+
Sbjct: 117 RT-CQKYIDKYGPLQELEETAARCVCPFCQRELYEDSLLDHCITHHRSERRPVFCPLCR 174


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 36/198 (18%), Positives = 91/198 (45%), Gaps = 3/198 (1%)

Query: 213 LLRSEGTNQQIKAHEASSAVQHVNLL--KEWSNSLEKKVSLLQNESVEKNKSIQSLHNQI 270
           L  SE +  Q+   E    ++    L  +  +N+L++++   + E  E+ K I+    ++
Sbjct: 198 LAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKM 257

Query: 271 CSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVE 330
              E  +  Q+  +R  E K+   ++ +  Q ++L+E +KE+R  ++  E+ + M+   E
Sbjct: 258 WRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEE 317

Query: 331 SLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYN 390
            +  +  ++   ++   +        E Q+   +Q +   + R+ + D R +  E     
Sbjct: 318 KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMRE 377

Query: 391 GVLIWKIRDYKRRKQEAV 408
              +W+ ++ K +++E +
Sbjct: 378 QEKMWE-QEEKMQEEERI 394



 Score = 33.5 bits (75), Expect = 0.51
 Identities = 33/176 (18%), Positives = 78/176 (44%), Gaps = 12/176 (6%)

Query: 238 LKEWSNSLEKKVSLLQNESV-EKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQR 296
           ++E     E++  + + E + E+ K ++     +   E ++++Q+E +   E K    QR
Sbjct: 375 MREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR 434

Query: 297 VIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVE--SLQNRVTELESVDKSAGQVARNTG 354
            +  Q EKL E +K      + WE+ + ++   E    + ++   E + +   Q+     
Sbjct: 435 -LPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ-- 491

Query: 355 LLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW----KIRDYKRRKQE 406
             E ++   +Q +   + R+ + D R +  E        +W    K+R+ K+ +++
Sbjct: 492 --EEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQ 545



 Score = 32.7 bits (73), Expect = 0.87
 Identities = 20/145 (13%), Positives = 67/145 (46%), Gaps = 8/145 (5%)

Query: 274 EIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQ 333
           E ++  Q+E +R+ E K+   +  +  Q E+L+E ++ +R  ++ W++ + M+   ++ +
Sbjct: 485 EDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQE 544

Query: 334 NRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVL 393
                 +  +K   +        E ++   ++M+   + ++ + + + +  E        
Sbjct: 545 QEKKTWDQEEKMREEERMRE--REKKMREEEEMMREQEEKMQEQEEKMREQEEK------ 596

Query: 394 IWKIRDYKRRKQEAVMGKTLSLYSQ 418
           +W+  +  + ++E +  +   ++ Q
Sbjct: 597 MWEQEEKMQEQEEKMWEQEEKMWEQ 621



 Score = 32.7 bits (73), Expect = 0.87
 Identities = 19/125 (15%), Positives = 56/125 (44%), Gaps = 4/125 (3%)

Query: 258 EKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQ 317
           E+ K ++     +   E +++ Q+E +R  E K+   +  +  Q EK+ E ++++     
Sbjct: 564 EREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM----W 619

Query: 318 NWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADM 377
             EE D M+   E +  +  +++  ++   +        E ++   ++ +   + ++ + 
Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQ 679

Query: 378 DLRFQ 382
           + + Q
Sbjct: 680 EEKMQ 684



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 24/138 (17%), Positives = 57/138 (41%), Gaps = 12/138 (8%)

Query: 239 KEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVI 298
           K W    E K+   +    E+ + +Q    ++   E ++  Q+E +R  E K+   +  +
Sbjct: 617 KMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 676

Query: 299 DSQAEKLKELDKEIRPFRQN--------WEEADSMKSSVESLQNRVTELESVDKSAGQVA 350
             Q EK++  ++++R   +         W + + M    E +  +    E  ++   Q  
Sbjct: 677 REQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKE 736

Query: 351 RNTGLLESQLSRHDQMLS 368
           +    ++ +L  H++  S
Sbjct: 737 K----MQERLPEHEERCS 750



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 22/111 (19%), Positives = 48/111 (43%), Gaps = 6/111 (5%)

Query: 215 RSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFE 274
           + E   +Q K  E    +Q    ++E    + ++   ++ +  +  K  +++  Q     
Sbjct: 371 KEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE---- 426

Query: 275 IEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSM 325
            E E Q++ L   + K+   Q  +  Q EK+ E +++IR   + W +   M
Sbjct: 427 -EKEWQQQRLPEQKEKLWE-QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM 475


>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
           sapiens]
          Length = 1116

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 41/165 (24%), Positives = 78/165 (47%), Gaps = 28/165 (16%)

Query: 219 TNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESV--------------EKNKSIQ 264
           T  +   ++ S + QH+ +LKE   + E++ ++LQ E                +K K IQ
Sbjct: 487 TKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQ 546

Query: 265 SLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADS 324
            +  +  +   EI   K+ML   E K+  LQ+ I++  E+L++ +K++           S
Sbjct: 547 DMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQM----------SS 596

Query: 325 MKSSVESLQ----NRVTELESVDKSAGQVARNTGLLESQLSRHDQ 365
           +K  V+SLQ    N  T L +++++  +  R    L+ Q  R ++
Sbjct: 597 LKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDER 641



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 33/169 (19%), Positives = 76/169 (44%), Gaps = 5/169 (2%)

Query: 211 QTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQI 270
           +T+L  +    Q  A E  +    ++ LK+  +  E+KV++LQ +     + ++    Q+
Sbjct: 535 ETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQM 594

Query: 271 CSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKEL-DKEIRPFRQNWEEADSMKSSV 329
            S +  ++  +    N ++ +  L+  +  +   ++ L ++  R  R+  EE D+ K  +
Sbjct: 595 SSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDL 654

Query: 330 ESLQNRVT----ELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRL 374
           + L+ +V+    +L   + S   +  +   L S   + D  L   +I L
Sbjct: 655 KDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIAL 703



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 45/229 (19%), Positives = 101/229 (44%), Gaps = 15/229 (6%)

Query: 158 LRKDLR-DHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRS 216
           L+KD R   +E A + ++  C   +SQ+        E    P +     H     T  + 
Sbjct: 690 LKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKD 749

Query: 217 EGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIE 276
           E +  Q +       ++ V   K   N  +KK++ L+ +  ++NK + +L ++    ++E
Sbjct: 750 ESSKAQAEVDRLLEILKEVENEK---NDKDKKIAELERQVKDQNKKVANLKHK---EQVE 803

Query: 277 IERQKEMLR-------NNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSV 329
            ++  +ML        N       LQ  +  + ++++EL++ +R   Q   E + + +  
Sbjct: 804 KKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQE 863

Query: 330 ESLQ-NRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADM 377
           ES + N   ++E +  +  +V +    ++++LS   Q L+  +  L ++
Sbjct: 864 ESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNL 912



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 42/211 (19%), Positives = 94/211 (44%), Gaps = 35/211 (16%)

Query: 154 KEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTL 213
           K  VL+K + +++++  + +E   S  K +V  +      +TD     +        + L
Sbjct: 572 KVNVLQKKI-ENLQEQLRDKEKQMSSLKERVKSLQADT-TNTDTALTTLE-------EAL 622

Query: 214 LRSEGTNQQIKAH---EASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSL---- 266
              E T +++K     +     + ++  K+    L++KVSLLQ +  EK  S+  L    
Sbjct: 623 AEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHA 682

Query: 267 ----------HNQICSFEIEIERQKEMLRNNESKILHLQ------RVIDSQAEKLKELDK 310
                      +++ + EI +E++KE     ES++          R     +++++ L++
Sbjct: 683 SSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLER 742

Query: 311 EIRPFRQNWEEADSMKSSVESLQNRVTELES 341
           EI  ++   +E+   ++ V+ L   + E+E+
Sbjct: 743 EITRYK---DESSKAQAEVDRLLEILKEVEN 770


>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
          Length = 1088

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 41/165 (24%), Positives = 78/165 (47%), Gaps = 28/165 (16%)

Query: 219 TNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESV--------------EKNKSIQ 264
           T  +   ++ S + QH+ +LKE   + E++ ++LQ E                +K K IQ
Sbjct: 459 TKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQ 518

Query: 265 SLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADS 324
            +  +  +   EI   K+ML   E K+  LQ+ I++  E+L++ +K++           S
Sbjct: 519 DMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQM----------SS 568

Query: 325 MKSSVESLQ----NRVTELESVDKSAGQVARNTGLLESQLSRHDQ 365
           +K  V+SLQ    N  T L +++++  +  R    L+ Q  R ++
Sbjct: 569 LKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDER 613



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 33/169 (19%), Positives = 76/169 (44%), Gaps = 5/169 (2%)

Query: 211 QTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQI 270
           +T+L  +    Q  A E  +    ++ LK+  +  E+KV++LQ +     + ++    Q+
Sbjct: 507 ETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQM 566

Query: 271 CSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKEL-DKEIRPFRQNWEEADSMKSSV 329
            S +  ++  +    N ++ +  L+  +  +   ++ L ++  R  R+  EE D+ K  +
Sbjct: 567 SSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDL 626

Query: 330 ESLQNRVT----ELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRL 374
           + L+ +V+    +L   + S   +  +   L S   + D  L   +I L
Sbjct: 627 KDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIAL 675



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 45/229 (19%), Positives = 101/229 (44%), Gaps = 15/229 (6%)

Query: 158 LRKDLR-DHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRS 216
           L+KD R   +E A + ++  C   +SQ+        E    P +     H     T  + 
Sbjct: 662 LKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKD 721

Query: 217 EGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIE 276
           E +  Q +       ++ V   K   N  +KK++ L+ +  ++NK + +L ++    ++E
Sbjct: 722 ESSKAQAEVDRLLEILKEVENEK---NDKDKKIAELERQVKDQNKKVANLKHK---EQVE 775

Query: 277 IERQKEMLR-------NNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSV 329
            ++  +ML        N       LQ  +  + ++++EL++ +R   Q   E + + +  
Sbjct: 776 KKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQE 835

Query: 330 ESLQ-NRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADM 377
           ES + N   ++E +  +  +V +    ++++LS   Q L+  +  L ++
Sbjct: 836 ESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNL 884



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 42/211 (19%), Positives = 94/211 (44%), Gaps = 35/211 (16%)

Query: 154 KEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTL 213
           K  VL+K + +++++  + +E   S  K +V  +      +TD     +        + L
Sbjct: 544 KVNVLQKKI-ENLQEQLRDKEKQMSSLKERVKSLQADT-TNTDTALTTLE-------EAL 594

Query: 214 LRSEGTNQQIKAH---EASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSL---- 266
              E T +++K     +     + ++  K+    L++KVSLLQ +  EK  S+  L    
Sbjct: 595 AEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHA 654

Query: 267 ----------HNQICSFEIEIERQKEMLRNNESKILHLQ------RVIDSQAEKLKELDK 310
                      +++ + EI +E++KE     ES++          R     +++++ L++
Sbjct: 655 SSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLER 714

Query: 311 EIRPFRQNWEEADSMKSSVESLQNRVTELES 341
           EI  ++   +E+   ++ V+ L   + E+E+
Sbjct: 715 EITRYK---DESSKAQAEVDRLLEILKEVEN 742


>gi|45594312 TNF receptor-associated factor 7 [Homo sapiens]
          Length = 670

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 62/288 (21%), Positives = 102/288 (35%), Gaps = 52/288 (18%)

Query: 21  LHTDRSAG--TPVFVPEQGGYKEKFVKTVEDKYK--CEKCHLVLCSPKQTECGHRFCESC 76
           LH++ S    +   +PE+    E  V   +   K  C+ C  V   P  T CGH FC  C
Sbjct: 95  LHSESSMSLRSTFSLPEEEEEPEPLVFAEQPSVKLCCQLCCSVFKDPVITTCGHTFCRRC 154

Query: 77  MAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVH 136
                   + K   C    VK  V  +N    E                    +G L +H
Sbjct: 155 --------ALKSEKCPVDNVKLTVVVNNIAVAE-------------------QIGELFIH 187

Query: 137 LKNDCHFE---ELPCVRPD---CKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQ 190
            ++ C      + P    D   C   +     +DH E +C YR   C +  S  P++ + 
Sbjct: 188 CRHGCRVAGSGKPPIFEVDPRGCPFTIKLSARKDH-EGSCDYRPVRCPNNPSCPPLLRMN 246

Query: 191 KHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVS 250
                   C  + CPH     T + ++ T      +E          LKE+    + +  
Sbjct: 247 LEAHLK-ECEHIKCPHSKYGCTFIGNQDT------YETHLETCRFEGLKEFLQQTDDRFH 299

Query: 251 LLQNESVEKNKSIQ-------SLHNQICSFEIEIERQKEMLRNNESKI 291
            +     +K++ I         L  +I   E  +E + ++L  N+SK+
Sbjct: 300 EMHVALAQKDQEIAFLRSMLGKLSEKIDQLEKSLELKFDVLDENQSKL 347


>gi|19920317 cytoskeleton-associated protein 4 [Homo sapiens]
          Length = 602

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 44/193 (22%), Positives = 89/193 (46%), Gaps = 19/193 (9%)

Query: 207 KCSVQTLLRSEGTNQQIKA-HEASSAVQHVNLLKEWS-NSLEKKVSLLQNESVEKNKSIQ 264
           K  V +L  SEG  Q +KA  EA   +Q     +EW   +L   +  ++++   + + + 
Sbjct: 270 KAKVASLEESEGNKQDLKALKEAVKEIQTSAKSREWDMEALRSTLQTMESDIYTEVRELV 329

Query: 265 SLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFR-------- 316
           SL  +  +F+   + ++  L+    K+L  +  +    E+++ L++E+R  +        
Sbjct: 330 SLKQEQQAFKEAADTERLALQALTEKLLRSEESVSRLPEEIRRLEEELRQLKSDSHGPKE 389

Query: 317 ----QNWEEADSMKSSVESLQNRVTELE-SVDKSAGQVARNTGLLESQLSRHDQMLSVHD 371
               ++ E  ++++   + L +R+  +E  V       AR T  LES LS+  +    H+
Sbjct: 390 DGGFRHSEAFEALQQKSQGLDSRLQHVEDGVLSMQVASARQTESLESLLSKSQE----HE 445

Query: 372 IRLADMDLRFQVL 384
            RLA +  R + L
Sbjct: 446 QRLAALQGRLEGL 458


>gi|30520320 ring finger protein 166 [Homo sapiens]
          Length = 237

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 5/100 (5%)

Query: 47  VEDKYKCEKCHLVLCSPKQT-ECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNC 105
           +E +Y C  C  V   P     CGH FC  C+   L   SP C  C+      KV K   
Sbjct: 27  LEAQYTCPICLEVYHRPVAIGSCGHTFCGECLQPCLQVPSPLCPLCRLPFDPKKVDKATH 86

Query: 106 CKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEE 145
            ++++ + +  C    RGC +++ L  + VH+ +    +E
Sbjct: 87  VEKQLSSYKAPC----RGCNKKVTLAKMRVHISSCLKVQE 122


>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
          Length = 1417

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 36/161 (22%), Positives = 80/161 (49%), Gaps = 16/161 (9%)

Query: 227  EASSAVQHVNL-LKEWSNSLEKKVSLLQN-------ESVEKNKSIQSLHNQICSFEIEIE 278
            + ++ V H+++ ++E    +E+K+  L+        E  E NK I+SL++++ + + ++ 
Sbjct: 1141 QRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLR 1200

Query: 279  RQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQ----NWEEA----DSMKSSVE 330
             ++ ++  NE +I  L++ I+   +++KE++  ++   Q     ++EA      ++ + E
Sbjct: 1201 EKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTRE 1260

Query: 331  SLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHD 371
             +QN  TEL        Q  R    L S+L    Q+    D
Sbjct: 1261 QVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKD 1301



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 37/141 (26%), Positives = 64/141 (45%), Gaps = 17/141 (12%)

Query: 211  QTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEK------KVSLLQNESVEKNKSIQ 264
            +T+   E  + Q K  +  S ++   L K+  +S EK      K     +E+  K + + 
Sbjct: 921  ETIRNGELEDTQTKLEKQVSKLEQ-ELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVI 979

Query: 265  SLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADS 324
             L       +IE+++ KE L   E +I+HL+R  +++A  L +LD  +          D 
Sbjct: 980  ELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMIL----------DQ 1029

Query: 325  MKSSVESLQNRVTELESVDKS 345
             K+ +E   N V ELE +  S
Sbjct: 1030 TKTELEKKTNAVKELEKLQHS 1050



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 39/175 (22%), Positives = 78/175 (44%), Gaps = 26/175 (14%)

Query: 214  LRSEGTNQQIKAHEASSAVQ--------HVNLLK----EWSNSLEKK---VSLLQNESVE 258
            L+++ + + IK  +  SA++        H+N L+    ++   L+KK   V  LQ E   
Sbjct: 833  LQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKI 892

Query: 259  KNKSIQSLHNQICSFEIEIERQKEMLRN---NESKILHLQRVIDSQAEKL-----KELDK 310
            KN S+Q    Q    +  +++Q++ML+       ++   Q  ++ Q  KL     K+ + 
Sbjct: 893  KNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRES 952

Query: 311  EIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQ 365
                 R+  E+ +S     +  + +V EL     +A QV       + +LS+ ++
Sbjct: 953  SAEKLRKMEEKCESAAHEADLKRQKVIELTG---TARQVKIEMDQYKEELSKMEK 1004



 Score = 33.1 bits (74), Expect = 0.67
 Identities = 42/206 (20%), Positives = 81/206 (39%), Gaps = 48/206 (23%)

Query: 233 QHVNLLKEWSNSLEK----------------------------KVSLLQNESVEKNKSIQ 264
           Q +  L+E  N L +                            KVS+L++ + ++  S+ 
Sbjct: 229 QEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLES-AQQQAASVP 287

Query: 265 SLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEI------------ 312
            L  QI + E E+  Q ++LR  E+K+   Q+++  + + L+E  +E             
Sbjct: 288 ILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTK 347

Query: 313 ---RPFRQNWE---EADSMKSSVESLQNRVTE-LESVDKSAGQVARNTGLLESQLSRHDQ 365
              R  RQ  E    A+ +  + +  + +V E LE V      + RN    E +  R  +
Sbjct: 348 QGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQE 407

Query: 366 MLSVHDIRLADMDLRFQVLETASYNG 391
              ++   L  +  + + L+  + NG
Sbjct: 408 RCGLYKSELEILKEKLRQLKEENNNG 433



 Score = 29.6 bits (65), Expect = 7.4
 Identities = 22/84 (26%), Positives = 44/84 (52%), Gaps = 7/84 (8%)

Query: 238 LKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRN-----NESKIL 292
           LKE +N+ ++K+ ++  ++ E    +      I   E E+E + E+LR+     NE++ L
Sbjct: 426 LKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENREL 485

Query: 293 HLQRVIDSQAEKLKELDKEIRPFR 316
            ++  + +Q E+L    +EI   R
Sbjct: 486 KVR--VAAQNERLDLCQQEIESSR 507


>gi|21361539 ring finger protein 138 isoform 1 [Homo sapiens]
          Length = 245

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 8/96 (8%)

Query: 48  EDKYKCEKCHLVLCSP-KQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCC 106
           ED + C  C  VL +P + T C H FC  C    +  S   C  C+ ++ +    ++  C
Sbjct: 13  EDDFYCPVCQEVLKTPVRTTACQHVFCRKCFLTAMRESGAHCPLCRGNVTR----RERAC 68

Query: 107 KREILALQIYCRNES---RGCAEQLMLGHLLVHLKN 139
               L L+   R  S   R CA+Q+    +  H K+
Sbjct: 69  PERALDLENIMRKFSGSCRCCAKQIKFYRMRHHYKS 104


>gi|124517695 ankyrin repeat domain 36B [Homo sapiens]
          Length = 1121

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 65/285 (22%), Positives = 125/285 (43%), Gaps = 34/285 (11%)

Query: 144 EELPCVRPDCKEKV-LRKDLRDHVEKACKYRE---ATCSHCKSQVPMIALQKHEDTDCPC 199
           EE    +P  K ++  R DL D ++ +    E   + C +CK+ + +I   + +  DC  
Sbjct: 515 EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVH 574

Query: 200 VVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEK 259
           ++      C  + L++       +K +        +  LK  ++ L+K++S  +    + 
Sbjct: 575 LLKIKNTFCLWKRLIK-------LKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQL 627

Query: 260 NKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNW 319
              I  L  ++CS    I+++K+  RN E   LH Q+V     EKL+  +++ R      
Sbjct: 628 KHEILELEKELCSLRFAIQQEKKKRRNVEE--LH-QKV----REKLRITEEQYR------ 674

Query: 320 EEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDI---RLAD 376
            EAD  K    +L++   EL++   ++ QV+      E +   H+  L   +I   RL  
Sbjct: 675 IEADVTKPIKPALKSAEVELKTGGNNSNQVSETD---EKEDLLHENRLMQDEIARLRLEK 731

Query: 377 MDLRFQVLETASYNGVLIWKIR--DYKR--RKQEAVMGKTLSLYS 417
             ++ Q LE        I K +  D ++  ++    + KT++ YS
Sbjct: 732 DTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYS 776


>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
          Length = 1524

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 61/285 (21%), Positives = 122/285 (42%), Gaps = 34/285 (11%)

Query: 144  EELPCVRPDCKEKV-LRKDLRDHVEKACKYRE---ATCSHCKSQVPMIALQKHEDTDCPC 199
            EE    +P  K ++  R DL D ++ +    E   + C +CK+ + +I   + +  DC  
Sbjct: 918  EEYENNQPQVKNQIHSRDDLDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVH 977

Query: 200  VVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEK 259
            ++      C  + L++       +K +        +  LK  ++ L+K++S  +    + 
Sbjct: 978  LLKIKNTFCLWKRLIK-------LKDNHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQL 1030

Query: 260  NKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNW 319
               I  L  ++CS    I+++K+  RN       ++ V     EKL+  +++ R      
Sbjct: 1031 KHEILELEKELCSLRFAIQQEKKKRRN-------VEEVHQKVREKLRITEEQYR------ 1077

Query: 320  EEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDI---RLAD 376
             EAD  K    +L++   EL++   ++ QV+      E +   H+  L   +I   RL  
Sbjct: 1078 IEADVTKPIKPALKSAEVELKTGGNNSNQVSETD---EKEDLLHENRLMQDEIARLRLEK 1134

Query: 377  MDLRFQVLETASYNGVLIWKIR--DYKR--RKQEAVMGKTLSLYS 417
              ++ Q LE        I K +  D ++  ++    + KT++ YS
Sbjct: 1135 DTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIACYS 1179


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 24/123 (19%), Positives = 59/123 (47%), Gaps = 1/123 (0%)

Query: 246 EKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKL 305
           E+K+   +  + E+ + +     ++C  E +++ Q+E +R  E KI   ++ I  Q EK+
Sbjct: 598 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKI 657

Query: 306 KELDKEIRPFRQN-WEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHD 364
           +E ++ ++   +  WE+ + M    E +Q +  ++   ++   +        E ++  H 
Sbjct: 658 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 717

Query: 365 QML 367
           + L
Sbjct: 718 EHL 720



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 44/226 (19%), Positives = 92/226 (40%), Gaps = 23/226 (10%)

Query: 214 LRSEGTNQQIKAHEASSAVQHVNL-LKEWSNSLEKKVSLL-----QNESVEKNKSIQSLH 267
           L+ +    Q K     S    + L +KE    LE+   LL     Q E+    K +QS+ 
Sbjct: 280 LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVS 339

Query: 268 NQICSFEIEIE-------RQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQN-- 318
            ++ +   E E       +Q+E +   E KI   +  I  Q EK++E +++IR   +   
Sbjct: 340 AKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMR 399

Query: 319 ------WEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDI 372
                 WE+ + M+   E +  +  ++   ++   +       LE ++   +++    + 
Sbjct: 400 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 459

Query: 373 RLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQ 418
           R  +  +R Q  E        +W+  +  R ++E +  +   ++ Q
Sbjct: 460 RQEEEKIREQ--EKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQ 503



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 28/173 (16%), Positives = 75/173 (43%), Gaps = 9/173 (5%)

Query: 215 RSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESV-EKNKSIQSLHNQICSF 273
           + E  ++Q K  E     +   + ++     E++    Q E + E+ + I+    ++   
Sbjct: 503 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQ 562

Query: 274 EIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQ--------NWEEADSM 325
           E ++  Q+E +R  E K+   +  I  Q EK++E +++IR   +          E+ + M
Sbjct: 563 EEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM 622

Query: 326 KSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMD 378
               E +Q +  ++   ++   +  +     E ++   ++M+   + ++ + +
Sbjct: 623 CEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 675



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 26/117 (22%), Positives = 51/117 (43%), Gaps = 7/117 (5%)

Query: 221 QQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSI----QSLHNQ---ICSF 273
           Q+ K       +     ++E     E++    Q E + + + I    + +H Q   I   
Sbjct: 496 QEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQ 555

Query: 274 EIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVE 330
           E ++ RQ+E + + E KI   +  +  Q EK++E +++IR   +   E + M    E
Sbjct: 556 EEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQE 612



 Score = 29.3 bits (64), Expect = 9.6
 Identities = 29/156 (18%), Positives = 68/156 (43%), Gaps = 18/156 (11%)

Query: 255 ESVEKNKSIQSLHNQICSFEIEIE--RQKEMLRNNESKILHLQRVIDSQAEKLKELDKEI 312
           E  EK +  + +  Q    E E +  RQ+E +R  E KI   +  +  Q EK+ E +K I
Sbjct: 455 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEK-I 513

Query: 313 RPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDI 372
           R   +  E+ +  +      + ++ E E + +   ++       E ++ + ++ +   + 
Sbjct: 514 REEEKRQEQEEMWRQ-----EEKIREQEEIWRQKEKIHEQ----EEKIRKQEEKMWRQEE 564

Query: 373 RLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAV 408
           ++ D + + +  E        +W+  +  R ++E +
Sbjct: 565 KMHDQEEKIREQEEK------VWRQEEKIREQEEKI 594


>gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]
          Length = 1194

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 36/147 (24%), Positives = 64/147 (43%), Gaps = 15/147 (10%)

Query: 224 KAHEASSAVQHVNLLKE---WSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQ 280
           KA EA+S +Q    LKE       +E++++ L+   +   +   SLH+     E E+  +
Sbjct: 279 KAEEANSKLQRD--LKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASK 336

Query: 281 KEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELE 340
           + + R +E K   L   +D   +KL          +Q  ++A+++      L  RV  L 
Sbjct: 337 ESLYRQSEEKSRQLAEWLDDAKQKL----------QQTLQKAETLPEIEAQLAQRVAALN 386

Query: 341 SVDKSAGQVARNTGLLESQLSRHDQML 367
             ++  G        LE+QL   +Q L
Sbjct: 387 KAEERHGNFEERLRQLEAQLEEKNQEL 413


>gi|190194355 p90 autoantigen [Homo sapiens]
          Length = 905

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 39/169 (23%), Positives = 81/169 (47%), Gaps = 16/169 (9%)

Query: 207 KCSVQTLLRSEGTNQQIKAHEAS--SAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQ 264
           K  ++ L R+E T ++ K  + +  S  + +  +K+ + SL+++      + +EK +  +
Sbjct: 729 KSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRK 788

Query: 265 SLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADS 324
            + NQ+   E ++    +  +  E KI  LQ+  + + E +  L KE+    Q  +E   
Sbjct: 789 EVQNQLVDREHKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSI 848

Query: 325 MKSSVE----SLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSV 369
             SS+E     L+ R+ E ES+ K          L + +L++H  M+++
Sbjct: 849 KASSLEVQKAQLEGRLEEKESLVK----------LQQEELNKHSHMIAM 887


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.132    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,955,936
Number of Sequences: 37866
Number of extensions: 958215
Number of successful extensions: 6788
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 232
Number of HSP's successfully gapped in prelim test: 493
Number of HSP's that attempted gapping in prelim test: 5182
Number of HSP's gapped (non-prelim): 1712
length of query: 543
length of database: 18,247,518
effective HSP length: 107
effective length of query: 436
effective length of database: 14,195,856
effective search space: 6189393216
effective search space used: 6189393216
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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