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Search of human proteins with 22027551
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22027551 voltage-dependent calcium channel gamma-5 subunit
isoform a [Homo sapiens]
(275 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22027551 voltage-dependent calcium channel gamma-5 subunit is... 559 e-159
gi|21361975 voltage-dependent calcium channel gamma-7 subunit [H... 415 e-116
gi|7656950 voltage-dependent calcium channel gamma-5 subunit iso... 380 e-106
gi|7656948 voltage-dependent calcium channel gamma-4 subunit [Ho... 125 3e-29
gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Ho... 120 1e-27
gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Ho... 118 5e-27
gi|24586686 voltage-dependent calcium channel gamma-8 subunit [H... 118 5e-27
gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens] 49 5e-06
gi|226437592 transmembrane protein 114 [Homo sapiens] 49 5e-06
gi|4502539 voltage-dependent calcium channel gamma-1 subunit [Ho... 48 1e-05
gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo... 47 1e-05
gi|183979973 claudin 19 isoform a [Homo sapiens] 42 6e-04
gi|183979975 claudin 19 isoform b [Homo sapiens] 42 6e-04
gi|22748835 transmembrane protein 178 [Homo sapiens] 42 6e-04
gi|10863887 claudin 1 [Homo sapiens] 40 0.002
gi|153792186 claudin 7 [Homo sapiens] 37 0.014
gi|5921465 claudin 10 isoform b [Homo sapiens] 37 0.014
gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2 ... 36 0.032
gi|4505907 peripheral myelin protein 22 [Homo sapiens] 36 0.032
gi|24430165 peripheral myelin protein 22 [Homo sapiens] 36 0.032
gi|24430163 peripheral myelin protein 22 [Homo sapiens] 36 0.032
gi|93588657 claudin domain containing 1 protein isoform d [Homo ... 36 0.042
gi|93588650 claudin domain containing 1 protein isoform a [Homo ... 36 0.042
gi|93588620 claudin domain containing 1 protein isoform b [Homo ... 36 0.042
gi|93588614 claudin domain containing 1 protein isoform a [Homo ... 36 0.042
gi|93588624 claudin domain containing 1 protein isoform a [Homo ... 36 0.042
gi|11096340 claudin domain containing 1 protein isoform a [Homo ... 36 0.042
gi|157951718 GSG1-like isoform 1 [Homo sapiens] 36 0.042
gi|169211272 PREDICTED: germ cell-specific gene 1-like protein 2... 34 0.12
gi|169211660 PREDICTED: germ cell-specific gene 1-like protein 2... 34 0.12
>gi|22027551 voltage-dependent calcium channel gamma-5 subunit
isoform a [Homo sapiens]
Length = 275
Score = 559 bits (1440), Expect = e-159
Identities = 275/275 (100%), Positives = 275/275 (100%)
Query: 1 MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWR 60
MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWR
Sbjct: 1 MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWR 60
Query: 61 VCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNI 120
VCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNI
Sbjct: 61 VCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNI 120
Query: 121 GHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFA 180
GHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFA
Sbjct: 121 GHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFA 180
Query: 181 FAAISFLLTESAGVMSVYLFMKRYTAEDMYRPHPGFYRPRLSNCSDYSGQFLHPDAWVRG 240
FAAISFLLTESAGVMSVYLFMKRYTAEDMYRPHPGFYRPRLSNCSDYSGQFLHPDAWVRG
Sbjct: 181 FAAISFLLTESAGVMSVYLFMKRYTAEDMYRPHPGFYRPRLSNCSDYSGQFLHPDAWVRG 240
Query: 241 RSPSDISSEASLQMNSNYPALLKCPDYDQMSSSPC 275
RSPSDISSEASLQMNSNYPALLKCPDYDQMSSSPC
Sbjct: 241 RSPSDISSEASLQMNSNYPALLKCPDYDQMSSSPC 275
>gi|21361975 voltage-dependent calcium channel gamma-7 subunit [Homo
sapiens]
Length = 275
Score = 415 bits (1066), Expect = e-116
Identities = 194/275 (70%), Positives = 229/275 (83%)
Query: 1 MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWR 60
MS C +ALTLLSSVF CGL L+GIAVSTDYWLY+EEG ++PQNQ+TE+KM+LH+GLWR
Sbjct: 1 MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWR 60
Query: 61 VCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNI 120
VCF AG E+GRC EY + L +E+T N+LK +R+ATPFP+VSLF +F F+++NI
Sbjct: 61 VCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNI 120
Query: 121 GHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFA 180
GHIRP RTILAFVSGIFFILSGLSLVVGLVLYISSINDE++NR +E YF+Y+YGWSFA
Sbjct: 121 GHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFA 180
Query: 181 FAAISFLLTESAGVMSVYLFMKRYTAEDMYRPHPGFYRPRLSNCSDYSGQFLHPDAWVRG 240
FAA SFLL E AGVMSVYLF KRY E+MYRPHP FYRPRLS+CSDYSGQFL P+AW RG
Sbjct: 181 FAASSFLLKEGAGVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQPEAWRRG 240
Query: 241 RSPSDISSEASLQMNSNYPALLKCPDYDQMSSSPC 275
RSPSDISS+ S+QM NYP +K PD+ +S+SPC
Sbjct: 241 RSPSDISSDVSIQMTQNYPPAIKYPDHLHISTSPC 275
>gi|7656950 voltage-dependent calcium channel gamma-5 subunit
isoform b [Homo sapiens]
Length = 296
Score = 380 bits (975), Expect = e-106
Identities = 195/203 (96%), Positives = 195/203 (96%), Gaps = 3/203 (1%)
Query: 1 MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWR 60
MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWR
Sbjct: 1 MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWR 60
Query: 61 VCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNI 120
VCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNI
Sbjct: 61 VCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNI 120
Query: 121 GHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFA 180
GHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFA
Sbjct: 121 GHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFA 180
Query: 181 FAAISFLLTESAGVMSVYLFMKR 203
FAAISFLLTE V V L M R
Sbjct: 181 FAAISFLLTE---VKPVTLSMDR 200
>gi|7656948 voltage-dependent calcium channel gamma-4 subunit [Homo
sapiens]
Length = 327
Score = 125 bits (315), Expect = 3e-29
Identities = 65/211 (30%), Positives = 117/211 (55%), Gaps = 10/211 (4%)
Query: 1 MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMS------- 53
M C R LL++ A L+ IA+ TDYWLY + N + +
Sbjct: 1 MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGD 60
Query: 54 -LHSGLWRVCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMF 112
HSGLWRVC + G +G CF I + P + +S+ +L+++R+++ FP++S +
Sbjct: 61 LTHSGLWRVCCIEGIYKGHCFRINH-FPEDNDYDHDSSEYLLRIVRASSVFPILSTILLL 119
Query: 113 IGFILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFN 172
+G + G I + + +GI F+ +GLS ++G+++YISS + ++ +D + +
Sbjct: 120 LGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDK-RDEDKKNH 178
Query: 173 YKYGWSFAFAAISFLLTESAGVMSVYLFMKR 203
Y YGWSF F A+SF++ E+ GV++V +++++
Sbjct: 179 YNYGWSFYFGALSFIVAETVGVLAVNIYIEK 209
>gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Homo
sapiens]
Length = 323
Score = 120 bits (301), Expect = 1e-27
Identities = 69/210 (32%), Positives = 119/210 (56%), Gaps = 11/210 (5%)
Query: 1 MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVI----VPQNQSTEI--KMSL 54
M R LL++V A L+ IAV TDYWLY GV V +N++++ ++
Sbjct: 1 MGLFDRGVQMLLTTVGAFAAFSLMTIAVGTDYWLY-SRGVCKTKSVSENETSKKNEEVMT 59
Query: 55 HSGLWRVCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIG 114
HSGLWR C L G +G C I++ P + +++ L+ +R+++ FP++S+ +F+G
Sbjct: 60 HSGLWRTCCLEGNFKGLCKQIDH-FPEDADYEADTAEYFLRAVRASSIFPILSVILLFMG 118
Query: 115 FILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYK 174
+ R + +GIFF+ +GLS ++G+++YIS+ + +K +Y
Sbjct: 119 GLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISA---NAGDPSKSDSKKNSYS 175
Query: 175 YGWSFAFAAISFLLTESAGVMSVYLFMKRY 204
YGWSF F A+SF++ E GV++V++F+ R+
Sbjct: 176 YGWSFYFGALSFIIAEMVGVLAVHMFIDRH 205
>gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Homo
sapiens]
Length = 315
Score = 118 bits (296), Expect = 5e-27
Identities = 67/210 (31%), Positives = 116/210 (55%), Gaps = 12/210 (5%)
Query: 1 MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEI------KMSL 54
M C R L+++V A L+ IAV TDYWLY GV ++ S ++
Sbjct: 1 MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLY-SRGVCRTKSTSDNETSRKNEEVMT 59
Query: 55 HSGLWRVCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIG 114
HSGLWR C L G RG C I++ P + ++ +L+ +R+++ FP++S+ +F G
Sbjct: 60 HSGLWRTCCLEGAFRGVCKKIDH-FPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFFG 118
Query: 115 FILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYK 174
+ R + +GIFF+ +GLS ++G+++YIS+ + R ++ +Y
Sbjct: 119 GLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQR----DSKKSYS 174
Query: 175 YGWSFAFAAISFLLTESAGVMSVYLFMKRY 204
YGWSF F A SF++ E GV++V+++++++
Sbjct: 175 YGWSFYFGAFSFIIAEIVGVVAVHIYIEKH 204
>gi|24586686 voltage-dependent calcium channel gamma-8 subunit [Homo
sapiens]
Length = 425
Score = 118 bits (296), Expect = 5e-27
Identities = 67/218 (30%), Positives = 114/218 (52%), Gaps = 20/218 (9%)
Query: 4 CGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQN------------------ 45
C + LL++V A GL+ IA+STDYWLY + N
Sbjct: 15 CEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGAS 74
Query: 46 QSTEIKMSLHSGLWRVCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPL 105
+ + HSGLWR+C L G +RG C I + P +T +S +L+++R+++ FP+
Sbjct: 75 EKKDPGGLTHSGLWRICCLEGLKRGVCVKINH-FPEDTDYDHDSAEYLLRVVRASSIFPI 133
Query: 106 VSLFFMFIGFILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTK 165
+S + +G + + + + +GI F+ +GLS ++G+++YIS+ N +
Sbjct: 134 LSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISA-NAGEPGPKR 192
Query: 166 DAETYFNYKYGWSFAFAAISFLLTESAGVMSVYLFMKR 203
D E +Y YGWSF F +SF+L E GV++V ++++R
Sbjct: 193 DEEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIER 230
>gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens]
Length = 223
Score = 48.9 bits (115), Expect = 5e-06
Identities = 42/181 (23%), Positives = 76/181 (41%), Gaps = 21/181 (11%)
Query: 23 LLGIAVSTDYWLYLE-----------EGVIVPQNQSTEIKMSLHSGLWRVCFLAGEERGR 71
LL A+ TD+W ++ + ++ N+S +S HSGLWR C +
Sbjct: 22 LLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRTC----RVQSP 77
Query: 72 CFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIGHIRPHRTILA 131
C + + SES+ +L M + +SL M G + + + +L
Sbjct: 78 CTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLSFLL-QAYLLL 136
Query: 132 FVSGIFFILSGLSLVVGLVLYI----SSINDEM-LNRTKDAETYFNYKYGWSFAFAAISF 186
++GI F+ + + G+ +YI ++ + + L K + +GWS A ISF
Sbjct: 137 LLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFGWSLALGWISF 196
Query: 187 L 187
+
Sbjct: 197 I 197
>gi|226437592 transmembrane protein 114 [Homo sapiens]
Length = 223
Score = 48.9 bits (115), Expect = 5e-06
Identities = 42/181 (23%), Positives = 76/181 (41%), Gaps = 21/181 (11%)
Query: 23 LLGIAVSTDYWLYLE-----------EGVIVPQNQSTEIKMSLHSGLWRVCFLAGEERGR 71
LL A+ TD+W ++ + ++ N+S +S HSGLWR C +
Sbjct: 22 LLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRTC----RVQSP 77
Query: 72 CFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIGHIRPHRTILA 131
C + + SES+ +L M + +SL M G + + + +L
Sbjct: 78 CTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLSFLL-QAYLLL 136
Query: 132 FVSGIFFILSGLSLVVGLVLYI----SSINDEM-LNRTKDAETYFNYKYGWSFAFAAISF 186
++GI F+ + + G+ +YI ++ + + L K + +GWS A ISF
Sbjct: 137 LLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFGWSLALGWISF 196
Query: 187 L 187
+
Sbjct: 197 I 197
>gi|4502539 voltage-dependent calcium channel gamma-1 subunit [Homo
sapiens]
Length = 222
Score = 47.8 bits (112), Expect = 1e-05
Identities = 55/217 (25%), Positives = 94/217 (43%), Gaps = 35/217 (16%)
Query: 7 KALTLLSSVFAV-CGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWRVCF-- 63
K L + ++F + G+ L AV TD+W L + ++ +T + + H GLWR+C
Sbjct: 5 KMLKVRVTLFCILAGIVLAMTAVVTDHWAVLSPHM---EHHNTTCEAA-HFGLWRICTKR 60
Query: 64 -------------LAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFF 110
L GE+ C + P + E T I SA + SL F
Sbjct: 61 IPMDDSKTCGPITLPGEKN--CSYFRHFNPGESSEIFEFTTQKEYSI-SAAAIAIFSLGF 117
Query: 111 MFIGF--ILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAE 168
+ +G +L ++G R + L + +F+ +GL ++V + + S+ R D+E
Sbjct: 118 IILGSLCVLLSLGKKRDY---LLRPASMFYAFAGLCILVSVEVMRQSVK-----RMIDSE 169
Query: 169 --TYFNYKYGWSFAFAAISFLLTESAGVMSVYLFMKR 203
+ Y Y WSFA A +F+L G+ + + R
Sbjct: 170 DTVWIEYYYSWSFACACAAFILLFLGGLALLLFSLPR 206
>gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo
sapiens]
Length = 217
Score = 47.4 bits (111), Expect = 1e-05
Identities = 41/181 (22%), Positives = 76/181 (41%), Gaps = 21/181 (11%)
Query: 23 LLGIAVSTDYWLYLE-----------EGVIVPQNQSTEIKMSLHSGLWRVCFLAGEERGR 71
LL A+ T++W ++ + ++ N+S +S HSGLWR C +
Sbjct: 16 LLAAAIGTEFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRTC----RVQSP 71
Query: 72 CFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIGHIRPHRTILA 131
C + + SES+ +L M + +SL M G + + + +L
Sbjct: 72 CTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLSFLL-QAYLLL 130
Query: 132 FVSGIFFILSGLSLVVGLVLYI----SSINDEM-LNRTKDAETYFNYKYGWSFAFAAISF 186
++GI F+ + + G+ +YI ++ + + L K + +GWS A ISF
Sbjct: 131 LLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFGWSLALGWISF 190
Query: 187 L 187
+
Sbjct: 191 I 191
>gi|183979973 claudin 19 isoform a [Homo sapiens]
Length = 224
Score = 42.0 bits (97), Expect = 6e-04
Identities = 34/177 (19%), Positives = 71/177 (40%), Gaps = 17/177 (9%)
Query: 20 GLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIK-------MSLHSGLWRVCFLAGEERGRC 72
GL LLG ++ W+ + +PQ + + + L+ GLW C + +C
Sbjct: 5 GLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQC 64
Query: 73 FTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIGHIRP-HRTILA 131
+ ++ ++ + S + V+ ++ V++ +G +G P + +A
Sbjct: 65 KLYDSLLALDGHIQSARALMVVAVLLG-----FVAMVLSVVGMKCTRVGDSNPIAKGRVA 119
Query: 132 FVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYK----YGWSFAFAAI 184
G FIL+GL + + Y + + E N + + + GW+ A A+
Sbjct: 120 IAGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAV 176
>gi|183979975 claudin 19 isoform b [Homo sapiens]
Length = 211
Score = 42.0 bits (97), Expect = 6e-04
Identities = 34/177 (19%), Positives = 71/177 (40%), Gaps = 17/177 (9%)
Query: 20 GLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIK-------MSLHSGLWRVCFLAGEERGRC 72
GL LLG ++ W+ + +PQ + + + L+ GLW C + +C
Sbjct: 5 GLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQC 64
Query: 73 FTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIGHIRP-HRTILA 131
+ ++ ++ + S + V+ ++ V++ +G +G P + +A
Sbjct: 65 KLYDSLLALDGHIQSARALMVVAVLLG-----FVAMVLSVVGMKCTRVGDSNPIAKGRVA 119
Query: 132 FVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYK----YGWSFAFAAI 184
G FIL+GL + + Y + + E N + + + GW+ A A+
Sbjct: 120 IAGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAV 176
>gi|22748835 transmembrane protein 178 [Homo sapiens]
Length = 297
Score = 42.0 bits (97), Expect = 6e-04
Identities = 38/175 (21%), Positives = 76/175 (43%), Gaps = 28/175 (16%)
Query: 55 HSGLWRVCFLAGEERG-----------RCFTIEY---------VMPMN-TQLTSESTVNV 93
+SGLWR C+ G +R RC I+Y +P N T+ + ++
Sbjct: 111 YSGLWRKCYFLGIDRDIDTLILKGIAQRCTAIKYHFSQPIRLRNIPFNLTKTIQQDEWHL 170
Query: 94 LKMIRSATPFPLVSLFFMFIGFILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYI 153
L + R F +++ + G I+ + ++ V+G+ F+++G+ + L Y
Sbjct: 171 LHLRRITAGFLGMAVAVLLCGCIVATVSFFW-EESLTQHVAGLLFLMTGIFCTISLCTYA 229
Query: 154 SSINDEMLNRTK---DAETYFNYKYGWSF--AFAAISFLLTESAGVMSVYLFMKR 203
+SI+ ++ K + Y WS A+ ++ F++ + G+ Y F+ R
Sbjct: 230 ASISYDLNRLPKLIYSLPADVEHGYSWSIFCAWCSLGFIVA-AGGLCIAYPFISR 283
Score = 29.6 bits (65), Expect = 3.0
Identities = 13/28 (46%), Positives = 18/28 (64%)
Query: 6 RKALTLLSSVFAVCGLGLLGIAVSTDYW 33
R +T LS ++C LGLL A+ TD+W
Sbjct: 4 RALVTALSLGLSLCSLGLLVTAIFTDHW 31
>gi|10863887 claudin 1 [Homo sapiens]
Length = 211
Score = 40.4 bits (93), Expect = 0.002
Identities = 41/219 (18%), Positives = 89/219 (40%), Gaps = 18/219 (8%)
Query: 17 AVCGLGLLGIAVSTDYWLYLEEGVIVPQ-------NQSTEIKMSLHSGLWRVCFLAGEER 69
A GL LLG ++ W+ +PQ + +++ GLW C +
Sbjct: 2 ANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQ 61
Query: 70 GRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGF-ILNNIGHIRPHRT 128
+C + ++ +++ L + + V+ ++ ++++F +G + + +
Sbjct: 62 IQCKVFDSLLNLSSTLQATRALMVVGILLG-----VIAIFVATVGMKCMKCLEDDEVQKM 116
Query: 129 ILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFAFAAISFLL 188
+A + G F+L+GL+++V Y + I E + + + +AA S L
Sbjct: 117 RMAVIGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCL 176
Query: 189 TESAGVMSVYLFMKRYTAEDMYRPHPGFYRPRLSNCSDY 227
G + ++ T+ RP+P +P S+ DY
Sbjct: 177 L--GGALLCCSCPRKTTSYPTPRPYP---KPAPSSGKDY 210
>gi|153792186 claudin 7 [Homo sapiens]
Length = 211
Score = 37.4 bits (85), Expect = 0.014
Identities = 35/165 (21%), Positives = 67/165 (40%), Gaps = 15/165 (9%)
Query: 20 GLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIK-------MSLHSGLWRVCFLAGEERGRC 72
GL LLG +++ W+ L +PQ Q + +++ GLW C C
Sbjct: 5 GLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSC 64
Query: 73 FTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIG-HIRPHRTILA 131
+ V+ ++ L + + V+ ++ +++F +G G + + +A
Sbjct: 65 KMYDSVLALSAALQATRALMVVSLVLG-----FLAMFVATMGMKCTRCGGDDKVKKARIA 119
Query: 132 FVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYG 176
GI FI++GL+ +V Y I + N T Y++G
Sbjct: 120 MGGGIIFIVAGLAALVACSWYGHQIVTDFYNPL--IPTNIKYEFG 162
>gi|5921465 claudin 10 isoform b [Homo sapiens]
Length = 228
Score = 37.4 bits (85), Expect = 0.014
Identities = 32/156 (20%), Positives = 61/156 (39%), Gaps = 13/156 (8%)
Query: 8 ALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLH-SGLWRVCFLAG 66
A +++ + ++ G L+ + TDYW V T I + + + LW+ C
Sbjct: 5 ASEIIAFMVSISGWVLVSSTLPTDYWK-------VSTIDGTVITTATYWANLWKACVTDS 57
Query: 67 EERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIGHIRPH 126
C ++ ++ + + + + +A F G +G
Sbjct: 58 TGVSNCKDFPSMLALDGYIQACRGLMI-----AAVSLGFFGSIFALFGMKCTKVGGSDKA 112
Query: 127 RTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLN 162
+ +A ++GI FILSGL + G LY + I E +
Sbjct: 113 KAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFD 148
>gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2
[Homo sapiens]
Length = 173
Score = 36.2 bits (82), Expect = 0.032
Identities = 40/179 (22%), Positives = 71/179 (39%), Gaps = 42/179 (23%)
Query: 20 GLGLLGIAVSTDYWL-YLEEGVIVPQNQSTEIKMSLHSGLWRVCFLAGEERGRCFTIEYV 78
G LL +A++TD+W+ Y G H GLWR C +C+
Sbjct: 15 GTILLVVAMATDHWMQYRLSGSFA------------HQGLWRYCL-----GNKCY----- 52
Query: 79 MPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIGHIRP---HRTILAFVSG 135
L ++S + + F ++S G I+ + R F +G
Sbjct: 53 ------LQTDS----IAYWNATRAFMILSALCAISGIIMGIMAFAHQPTFSRISRPFSAG 102
Query: 136 IFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFAFAAISFLLTESAGV 194
I F S L +V+ L +Y + + L R + ++++ WS+ ++ L+T AG+
Sbjct: 103 IMFFSSTLFVVLALAIY-TGVTVSFLGRR-----FGDWRFSWSYILGWVAVLMTFFAGI 155
>gi|4505907 peripheral myelin protein 22 [Homo sapiens]
Length = 160
Score = 36.2 bits (82), Expect = 0.032
Identities = 47/193 (24%), Positives = 76/193 (39%), Gaps = 51/193 (26%)
Query: 8 ALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWRVCFLAGE 67
A+ +L V + ++G +TD W QN ST ++H CF +
Sbjct: 14 AVLVLLFVSTIVSQWIVGNGHATDLW----------QNCSTSSSGNVHH-----CFSSSP 58
Query: 68 ERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIG-FILNNIGHIRPH 126
N L S +L +I F ++SLF F F L G
Sbjct: 59 --------------NEWLQSVQATMILSII-----FSILSLFLFFCQLFTLTKGGRF--- 96
Query: 127 RTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFAFAAISF 186
+++GIF IL+GL ++ +Y + LN +Y YG+++ A ++F
Sbjct: 97 -----YITGIFQILAGLCVMSAAAIYTVRHPEWHLNS--------DYSYGFAYILAWVAF 143
Query: 187 LLTESAGVMSVYL 199
L +GV+ V L
Sbjct: 144 PLALLSGVIYVIL 156
>gi|24430165 peripheral myelin protein 22 [Homo sapiens]
Length = 160
Score = 36.2 bits (82), Expect = 0.032
Identities = 47/193 (24%), Positives = 76/193 (39%), Gaps = 51/193 (26%)
Query: 8 ALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWRVCFLAGE 67
A+ +L V + ++G +TD W QN ST ++H CF +
Sbjct: 14 AVLVLLFVSTIVSQWIVGNGHATDLW----------QNCSTSSSGNVHH-----CFSSSP 58
Query: 68 ERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIG-FILNNIGHIRPH 126
N L S +L +I F ++SLF F F L G
Sbjct: 59 --------------NEWLQSVQATMILSII-----FSILSLFLFFCQLFTLTKGGRF--- 96
Query: 127 RTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFAFAAISF 186
+++GIF IL+GL ++ +Y + LN +Y YG+++ A ++F
Sbjct: 97 -----YITGIFQILAGLCVMSAAAIYTVRHPEWHLNS--------DYSYGFAYILAWVAF 143
Query: 187 LLTESAGVMSVYL 199
L +GV+ V L
Sbjct: 144 PLALLSGVIYVIL 156
>gi|24430163 peripheral myelin protein 22 [Homo sapiens]
Length = 160
Score = 36.2 bits (82), Expect = 0.032
Identities = 47/193 (24%), Positives = 76/193 (39%), Gaps = 51/193 (26%)
Query: 8 ALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWRVCFLAGE 67
A+ +L V + ++G +TD W QN ST ++H CF +
Sbjct: 14 AVLVLLFVSTIVSQWIVGNGHATDLW----------QNCSTSSSGNVHH-----CFSSSP 58
Query: 68 ERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIG-FILNNIGHIRPH 126
N L S +L +I F ++SLF F F L G
Sbjct: 59 --------------NEWLQSVQATMILSII-----FSILSLFLFFCQLFTLTKGGRF--- 96
Query: 127 RTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFAFAAISF 186
+++GIF IL+GL ++ +Y + LN +Y YG+++ A ++F
Sbjct: 97 -----YITGIFQILAGLCVMSAAAIYTVRHPEWHLNS--------DYSYGFAYILAWVAF 143
Query: 187 LLTESAGVMSVYL 199
L +GV+ V L
Sbjct: 144 PLALLSGVIYVIL 156
>gi|93588657 claudin domain containing 1 protein isoform d [Homo
sapiens]
Length = 158
Score = 35.8 bits (81), Expect = 0.042
Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 8/112 (7%)
Query: 104 PLVSLFFMFIGFILNNIGHIRPHRTILAFVS-GIFFILSGLSLVVGLVLYISSINDEMLN 162
P VSL M G ++ I R++ ++ GI +L+GL + + Y++ I E+L+
Sbjct: 49 PFVSLGLMCFGALIGLCACIC--RSLYPTIATGILHLLAGLCTLGSVSCYVAGI--ELLH 104
Query: 163 RTKDAETYFNYKYGWSFAFAAISFLLTESAGVMSVYLF---MKRYTAEDMYR 211
+ + + ++GWSF A +S L A + ++ K YT YR
Sbjct: 105 QKLELPDNVSGEFGWSFCLACVSAPLQFMASALFIWAAHTNRKEYTLMKAYR 156
>gi|93588650 claudin domain containing 1 protein isoform a [Homo
sapiens]
Length = 253
Score = 35.8 bits (81), Expect = 0.042
Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 8/112 (7%)
Query: 104 PLVSLFFMFIGFILNNIGHIRPHRTILAFVS-GIFFILSGLSLVVGLVLYISSINDEMLN 162
P VSL M G ++ I R++ ++ GI +L+GL + + Y++ I E+L+
Sbjct: 144 PFVSLGLMCFGALIGLCACIC--RSLYPTIATGILHLLAGLCTLGSVSCYVAGI--ELLH 199
Query: 163 RTKDAETYFNYKYGWSFAFAAISFLLTESAGVMSVYLF---MKRYTAEDMYR 211
+ + + ++GWSF A +S L A + ++ K YT YR
Sbjct: 200 QKLELPDNVSGEFGWSFCLACVSAPLQFMASALFIWAAHTNRKEYTLMKAYR 251
>gi|93588620 claudin domain containing 1 protein isoform b [Homo
sapiens]
Length = 276
Score = 35.8 bits (81), Expect = 0.042
Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 8/112 (7%)
Query: 104 PLVSLFFMFIGFILNNIGHIRPHRTILAFVS-GIFFILSGLSLVVGLVLYISSINDEMLN 162
P VSL M G ++ I R++ ++ GI +L+GL + + Y++ I E+L+
Sbjct: 167 PFVSLGLMCFGALIGLCACIC--RSLYPTIATGILHLLAGLCTLGSVSCYVAGI--ELLH 222
Query: 163 RTKDAETYFNYKYGWSFAFAAISFLLTESAGVMSVYLF---MKRYTAEDMYR 211
+ + + ++GWSF A +S L A + ++ K YT YR
Sbjct: 223 QKLELPDNVSGEFGWSFCLACVSAPLQFMASALFIWAAHTNRKEYTLMKAYR 274
>gi|93588614 claudin domain containing 1 protein isoform a [Homo
sapiens]
Length = 253
Score = 35.8 bits (81), Expect = 0.042
Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 8/112 (7%)
Query: 104 PLVSLFFMFIGFILNNIGHIRPHRTILAFVS-GIFFILSGLSLVVGLVLYISSINDEMLN 162
P VSL M G ++ I R++ ++ GI +L+GL + + Y++ I E+L+
Sbjct: 144 PFVSLGLMCFGALIGLCACIC--RSLYPTIATGILHLLAGLCTLGSVSCYVAGI--ELLH 199
Query: 163 RTKDAETYFNYKYGWSFAFAAISFLLTESAGVMSVYLF---MKRYTAEDMYR 211
+ + + ++GWSF A +S L A + ++ K YT YR
Sbjct: 200 QKLELPDNVSGEFGWSFCLACVSAPLQFMASALFIWAAHTNRKEYTLMKAYR 251
>gi|93588624 claudin domain containing 1 protein isoform a [Homo
sapiens]
Length = 253
Score = 35.8 bits (81), Expect = 0.042
Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 8/112 (7%)
Query: 104 PLVSLFFMFIGFILNNIGHIRPHRTILAFVS-GIFFILSGLSLVVGLVLYISSINDEMLN 162
P VSL M G ++ I R++ ++ GI +L+GL + + Y++ I E+L+
Sbjct: 144 PFVSLGLMCFGALIGLCACIC--RSLYPTIATGILHLLAGLCTLGSVSCYVAGI--ELLH 199
Query: 163 RTKDAETYFNYKYGWSFAFAAISFLLTESAGVMSVYLF---MKRYTAEDMYR 211
+ + + ++GWSF A +S L A + ++ K YT YR
Sbjct: 200 QKLELPDNVSGEFGWSFCLACVSAPLQFMASALFIWAAHTNRKEYTLMKAYR 251
>gi|11096340 claudin domain containing 1 protein isoform a [Homo
sapiens]
Length = 253
Score = 35.8 bits (81), Expect = 0.042
Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 8/112 (7%)
Query: 104 PLVSLFFMFIGFILNNIGHIRPHRTILAFVS-GIFFILSGLSLVVGLVLYISSINDEMLN 162
P VSL M G ++ I R++ ++ GI +L+GL + + Y++ I E+L+
Sbjct: 144 PFVSLGLMCFGALIGLCACIC--RSLYPTIATGILHLLAGLCTLGSVSCYVAGI--ELLH 199
Query: 163 RTKDAETYFNYKYGWSFAFAAISFLLTESAGVMSVYLF---MKRYTAEDMYR 211
+ + + ++GWSF A +S L A + ++ K YT YR
Sbjct: 200 QKLELPDNVSGEFGWSFCLACVSAPLQFMASALFIWAAHTNRKEYTLMKAYR 251
>gi|157951718 GSG1-like isoform 1 [Homo sapiens]
Length = 331
Score = 35.8 bits (81), Expect = 0.042
Identities = 44/178 (24%), Positives = 75/178 (42%), Gaps = 20/178 (11%)
Query: 53 SLHSGLWRVCF--LAG-EERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLF 109
+ H+G+W C L+G E+ R F ++ SE V L ++ L+ +
Sbjct: 100 NFHTGIWYSCEEELSGLGEKCRSF-------IDLAPASEKGVLWLSVVSEVLYILLLVVG 152
Query: 110 FMFIGFILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAET 169
F + L + ++ + AF + +F +LSGL +V ++Y + +D
Sbjct: 153 FSLMCLELFHSSNVIDGLKLNAFAA-VFTVLSGLLGMVAHMMYTQVFQVTVSLGPEDWRP 211
Query: 170 YFNYKYGWSFAFAAISFLLTESAGVMSVYLFM--------KRYTAEDMYRPHPGFYRP 219
+ ++ YGWSF A SF +A V ++ + KR E YR P F P
Sbjct: 212 H-SWDYGWSFCLAWGSFTCCMAASVTTLNSYTKTVIEFRHKRKVFEQGYREEPTFIDP 268
>gi|169211272 PREDICTED: germ cell-specific gene 1-like protein
2-like [Homo sapiens]
Length = 293
Score = 34.3 bits (77), Expect = 0.12
Identities = 51/203 (25%), Positives = 85/203 (41%), Gaps = 27/203 (13%)
Query: 50 IKMSLHSGLWRVC--FLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVS 107
I+ H GLW+ C L GE+ +C + V+P E V L + L+
Sbjct: 84 IQRGFHVGLWQSCEESLNGEDE-KCRSFRSVVP-----AEEQGVLWLSIGGEVLDIVLIL 137
Query: 108 LFFMFIGFILNNIGHIRP--HRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTK 165
+ +G + + P H + + IF +L+GL +V ++Y ++I +N
Sbjct: 138 TSAILLG---SRVSCRSPGFHWLRVDALVAIFMVLAGLLGMVAHMMY-TTIFQITVNLGP 193
Query: 166 DAETYFNYKYGWSFAFAAISFLLTESAGVMSVYLFMKRYTAEDMYRPHPGFYRPRLSNCS 225
+ + YGWS+ A SF L + V + M R+TA + + + N S
Sbjct: 194 EDWKPQTWDYGWSYCLAWGSFALCLAVSVSA----MSRFTAARLEFTE----KQQAQNGS 245
Query: 226 DYS-GQFLHPDA----WVRGRSP 243
+S FL P+A W G +P
Sbjct: 246 RHSQHSFLEPEASESIWKTGAAP 268
>gi|169211660 PREDICTED: germ cell-specific gene 1-like protein
2-like [Homo sapiens]
Length = 293
Score = 34.3 bits (77), Expect = 0.12
Identities = 51/203 (25%), Positives = 85/203 (41%), Gaps = 27/203 (13%)
Query: 50 IKMSLHSGLWRVC--FLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVS 107
I+ H GLW+ C L GE+ +C + V+P E V L + L+
Sbjct: 84 IQRGFHVGLWQSCEESLNGEDE-KCRSFRSVVP-----AEEQGVLWLSIGGEVLDIVLIL 137
Query: 108 LFFMFIGFILNNIGHIRP--HRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTK 165
+ +G + + P H + + IF +L+GL +V ++Y ++I +N
Sbjct: 138 TSAILLG---SRVSCRSPGFHWLRVDALVAIFMVLAGLLGMVAHMMY-TTIFQITVNLGP 193
Query: 166 DAETYFNYKYGWSFAFAAISFLLTESAGVMSVYLFMKRYTAEDMYRPHPGFYRPRLSNCS 225
+ + YGWS+ A SF L + V + M R+TA + + + N S
Sbjct: 194 EDWKPQTWDYGWSYCLAWGSFALCLAVSVSA----MSRFTAARLEFTE----KQQAQNGS 245
Query: 226 DYS-GQFLHPDA----WVRGRSP 243
+S FL P+A W G +P
Sbjct: 246 RHSQHSFLEPEASESIWKTGAAP 268
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.138 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,652,461
Number of Sequences: 37866
Number of extensions: 387121
Number of successful extensions: 1193
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 41
Number of HSP's that attempted gapping in prelim test: 1144
Number of HSP's gapped (non-prelim): 63
length of query: 275
length of database: 18,247,518
effective HSP length: 101
effective length of query: 174
effective length of database: 14,423,052
effective search space: 2509611048
effective search space used: 2509611048
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.