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Search of human proteins with 219881540
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|219881540 hypothetical protein LOC199870 isoform 4 [Homo
sapiens]
(278 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|219881540 hypothetical protein LOC199870 isoform 4 [Homo sapi... 575 e-164
gi|22749341 hypothetical protein LOC199870 isoform 3 [Homo sapiens] 560 e-160
gi|219881538 hypothetical protein LOC199870 isoform 2 [Homo sapi... 556 e-159
gi|219881536 hypothetical protein LOC199870 isoform 1 [Homo sapi... 541 e-154
gi|221139693 hypothetical protein LOC199870 isoform 5 [Homo sapi... 417 e-117
gi|134288896 hypothetical protein LOC143684 [Homo sapiens] 408 e-114
gi|146229340 mutated in colorectal cancers isoform 1 [Homo sapiens] 42 6e-04
gi|4505129 mutated in colorectal cancers isoform 2 [Homo sapiens] 42 6e-04
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 40 0.002
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 40 0.002
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 40 0.002
gi|117414154 sodium channel associated protein 2 isoform b [Homo... 40 0.002
gi|117414162 sodium channel associated protein 2 isoform a [Homo... 40 0.002
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 39 0.004
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 39 0.005
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 39 0.007
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 39 0.007
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 39 0.007
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 38 0.009
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 38 0.009
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 38 0.009
gi|14195601 protein phosphatase 1, regulatory (inhibitor) subuni... 38 0.009
gi|14195599 protein phosphatase 1, regulatory (inhibitor) subuni... 38 0.009
gi|57768564 hypothetical protein LOC23281 isoform b [Homo sapiens] 38 0.009
gi|140161498 hypothetical protein LOC23281 isoform a [Homo sapiens] 38 0.009
gi|27436948 lamin A/C isoform 3 [Homo sapiens] 37 0.015
gi|5031875 lamin A/C isoform 2 [Homo sapiens] 37 0.015
gi|27436946 lamin A/C isoform 1 precursor [Homo sapiens] 37 0.015
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 37 0.015
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 37 0.019
>gi|219881540 hypothetical protein LOC199870 isoform 4 [Homo
sapiens]
Length = 278
Score = 575 bits (1483), Expect = e-164
Identities = 278/278 (100%), Positives = 278/278 (100%)
Query: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ 60
MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ
Sbjct: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ 60
Query: 61 NVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVD 120
NVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVD
Sbjct: 61 NVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVD 120
Query: 121 GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDS 180
GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDS
Sbjct: 121 GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDS 180
Query: 181 PGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEK 240
PGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEK
Sbjct: 181 PGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEK 240
Query: 241 THKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP 278
THKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP
Sbjct: 241 THKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP 278
>gi|22749341 hypothetical protein LOC199870 isoform 3 [Homo sapiens]
Length = 307
Score = 560 bits (1443), Expect = e-160
Identities = 278/307 (90%), Positives = 278/307 (90%), Gaps = 29/307 (9%)
Query: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ 60
MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ
Sbjct: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ 60
Query: 61 NVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVD 120
NVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVD
Sbjct: 61 NVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVD 120
Query: 121 GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNS--------- 171
GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNS
Sbjct: 121 GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSI 180
Query: 172 --------------------FSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMIL 211
FSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMIL
Sbjct: 181 QNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMIL 240
Query: 212 EKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEK 271
EKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEK
Sbjct: 241 EKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEK 300
Query: 272 SGAITSP 278
SGAITSP
Sbjct: 301 SGAITSP 307
>gi|219881538 hypothetical protein LOC199870 isoform 2 [Homo
sapiens]
Length = 312
Score = 556 bits (1433), Expect = e-159
Identities = 277/312 (88%), Positives = 277/312 (88%), Gaps = 34/312 (10%)
Query: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQES----------- 49
MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQE
Sbjct: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQERLECNGTISAHC 60
Query: 50 -----------------------KTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQ 86
KTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQ
Sbjct: 61 NLHLPGSSDSPASSSRVAGITGIKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQ 120
Query: 87 RCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHL 146
RCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHL
Sbjct: 121 RCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHL 180
Query: 147 SSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQK 206
SSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQK
Sbjct: 181 SSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQK 240
Query: 207 DQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKS 266
DQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKS
Sbjct: 241 DQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKS 300
Query: 267 KKSEKSGAITSP 278
KKSEKSGAITSP
Sbjct: 301 KKSEKSGAITSP 312
>gi|219881536 hypothetical protein LOC199870 isoform 1 [Homo
sapiens]
Length = 341
Score = 541 bits (1393), Expect = e-154
Identities = 277/341 (81%), Positives = 277/341 (81%), Gaps = 63/341 (18%)
Query: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQES----------- 49
MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQE
Sbjct: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQERLECNGTISAHC 60
Query: 50 -----------------------KTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQ 86
KTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQ
Sbjct: 61 NLHLPGSSDSPASSSRVAGITGIKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQ 120
Query: 87 RCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHL 146
RCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHL
Sbjct: 121 RCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHL 180
Query: 147 SSSSRAGHQEKEQYSRLSGGGHYNS-----------------------------FSPDLA 177
SSSSRAGHQEKEQYSRLSGGGHYNS FSPDLA
Sbjct: 181 SSSSRAGHQEKEQYSRLSGGGHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLA 240
Query: 178 LDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQ 237
LDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQ
Sbjct: 241 LDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQ 300
Query: 238 MEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP 278
MEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP
Sbjct: 301 MEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP 341
>gi|221139693 hypothetical protein LOC199870 isoform 5 [Homo
sapiens]
Length = 227
Score = 417 bits (1072), Expect = e-117
Identities = 219/278 (78%), Positives = 222/278 (79%), Gaps = 51/278 (18%)
Query: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQ 60
MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICK
Sbjct: 1 MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICK---- 56
Query: 61 NVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVD 120
+C + + YG VD
Sbjct: 57 --------------------------KCAQNVQLYGT---------------------VD 69
Query: 121 GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDS 180
GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDS
Sbjct: 70 GKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDS 129
Query: 181 PGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEK 240
PGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEK
Sbjct: 130 PGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEK 189
Query: 241 THKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP 278
THKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP
Sbjct: 190 THKEVTEQLQAKNRELLKQAAALSKSKKSEKSGAITSP 227
>gi|134288896 hypothetical protein LOC143684 [Homo sapiens]
Length = 339
Score = 408 bits (1048), Expect = e-114
Identities = 214/336 (63%), Positives = 245/336 (72%), Gaps = 59/336 (17%)
Query: 2 AALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQN 61
+ALYACTKC QR+PFE LSQGQQLCKECRIAHP+VKCTYCR+E+QQESKTNTICKKCAQN
Sbjct: 4 SALYACTKCTQRYPFEELSQGQQLCKECRIAHPIVKCTYCRSEFQQESKTNTICKKCAQN 63
Query: 62 VQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDD-RKKVD 120
V+ +GTPKPCQYCNIIAAFIG KCQRCTNSEKKYGPP +CEQCKQQCAFDRK++ R+KVD
Sbjct: 64 VKQFGTPKPCQYCNIIAAFIGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVD 123
Query: 121 GKLLCWLCTLSYKRVLQKTKEQRKHL----SSSSRAGHQEKEQ------------YSRLS 164
GKLLCWLCTLSYKRVLQKTKEQRK L S+SS + EK+Q + R S
Sbjct: 124 GKLLCWLCTLSYKRVLQKTKEQRKSLGSSHSNSSSSSLTEKDQHHPKHHHHHHHHHHRHS 183
Query: 165 GGGH-YNSFSPD----------------------------------------LALDSPGT 183
H ++ SP+ + DS GT
Sbjct: 184 SSHHKISNLSPEEEQGLWKQSHKSSATIQNETPKKKPKLESKPSNGDSSSINQSADSGGT 243
Query: 184 DHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHK 243
D+FV+I+QLKEEV +LK++L Q+DQ ILEK+KK+TELKADFQYQES +R KMN MEK HK
Sbjct: 244 DNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQESNLRTKMNSMEKAHK 303
Query: 244 EVTEQLQAKNRELLKQAAALSKSKKSEKSGAI-TSP 278
E EQLQAKNRELLKQ AALSK KK +KSG+I TSP
Sbjct: 304 ETVEQLQAKNRELLKQVAALSKGKKFDKSGSILTSP 339
>gi|146229340 mutated in colorectal cancers isoform 1 [Homo sapiens]
Length = 1019
Score = 42.0 bits (97), Expect = 6e-04
Identities = 31/87 (35%), Positives = 46/87 (52%), Gaps = 8/87 (9%)
Query: 192 LKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQA 251
+KEE+A LK L+ +LEKEKK ELK +E+Q +A + +E EV EQ +
Sbjct: 815 MKEEMAELKAQLY-----LLEKEKKALELK--LSTREAQEQAYLVHIEHLKSEVEEQKEQ 867
Query: 252 KNRELLKQAAALSKSKKSEKSGAITSP 278
+ R L ++ SK K ++ SP
Sbjct: 868 RMRSLSSTSSG-SKDKPGKECADAASP 893
>gi|4505129 mutated in colorectal cancers isoform 2 [Homo sapiens]
Length = 829
Score = 42.0 bits (97), Expect = 6e-04
Identities = 31/87 (35%), Positives = 46/87 (52%), Gaps = 8/87 (9%)
Query: 192 LKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQA 251
+KEE+A LK L+ +LEKEKK ELK +E+Q +A + +E EV EQ +
Sbjct: 625 MKEEMAELKAQLY-----LLEKEKKALELK--LSTREAQEQAYLVHIEHLKSEVEEQKEQ 677
Query: 252 KNRELLKQAAALSKSKKSEKSGAITSP 278
+ R L ++ SK K ++ SP
Sbjct: 678 RMRSLSSTSSG-SKDKPGKECADAASP 703
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 40.4 bits (93), Expect = 0.002
Identities = 36/139 (25%), Positives = 67/139 (48%), Gaps = 7/139 (5%)
Query: 136 LQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVI---IAQL 192
L+K KE+ K + A +++E+ R +S S D+ +F++ IA L
Sbjct: 386 LKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAM-YGNFMLKKDIAML 444
Query: 193 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAK 252
KEE+ +K +K++ +++ K ITE+ A+F E +R + KT ++QL
Sbjct: 445 KEELYAIKNDSLRKEKKYIQEIKSITEINANF---EKSVRLNEKMITKTVARYSQQLNDL 501
Query: 253 NRELLKQAAALSKSKKSEK 271
E + + L K K +++
Sbjct: 502 KAENARLNSELEKEKHNKE 520
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 40.4 bits (93), Expect = 0.002
Identities = 36/139 (25%), Positives = 67/139 (48%), Gaps = 7/139 (5%)
Query: 136 LQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVI---IAQL 192
L+K KE+ K + A +++E+ R +S S D+ +F++ IA L
Sbjct: 279 LKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAM-YGNFMLKKDIAML 337
Query: 193 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAK 252
KEE+ +K +K++ +++ K ITE+ A+F E +R + KT ++QL
Sbjct: 338 KEELYAIKNDSLRKEKKYIQEIKSITEINANF---EKSVRLNEKMITKTVARYSQQLNDL 394
Query: 253 NRELLKQAAALSKSKKSEK 271
E + + L K K +++
Sbjct: 395 KAENARLNSELEKEKHNKE 413
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 40.4 bits (93), Expect = 0.002
Identities = 36/139 (25%), Positives = 67/139 (48%), Gaps = 7/139 (5%)
Query: 136 LQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVI---IAQL 192
L+K KE+ K + A +++E+ R +S S D+ +F++ IA L
Sbjct: 386 LKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAM-YGNFMLKKDIAML 444
Query: 193 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAK 252
KEE+ +K +K++ +++ K ITE+ A+F E +R + KT ++QL
Sbjct: 445 KEELYAIKNDSLRKEKKYIQEIKSITEINANF---EKSVRLNEKMITKTVARYSQQLNDL 501
Query: 253 NRELLKQAAALSKSKKSEK 271
E + + L K K +++
Sbjct: 502 KAENARLNSELEKEKHNKE 520
>gi|117414154 sodium channel associated protein 2 isoform b [Homo
sapiens]
Length = 939
Score = 40.4 bits (93), Expect = 0.002
Identities = 17/84 (20%), Positives = 48/84 (57%)
Query: 187 VIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVT 246
V + ++++ +TL + H K +++ E ++ E+K F+ +E +++A+ ++ + K
Sbjct: 798 VELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKEKKLKAERDKSIELQKNAM 857
Query: 247 EQLQAKNRELLKQAAALSKSKKSE 270
E+L + + +Q A+ ++ ++E
Sbjct: 858 EKLHSMDDAFKRQVDAIVEAHQAE 881
Score = 33.9 bits (76), Expect = 0.16
Identities = 25/74 (33%), Positives = 41/74 (55%), Gaps = 9/74 (12%)
Query: 188 IIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTE 247
II E + LK L +KD+ I ++KITE++ + + Q+ K +Q++ EV E
Sbjct: 725 IIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIE---KCTQEQLDEKSSQLD----EVLE 777
Query: 248 QLQAKN--RELLKQ 259
+L+ N +E LKQ
Sbjct: 778 KLERHNERKEKLKQ 791
>gi|117414162 sodium channel associated protein 2 isoform a [Homo
sapiens]
Length = 1032
Score = 40.4 bits (93), Expect = 0.002
Identities = 17/84 (20%), Positives = 48/84 (57%)
Query: 187 VIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVT 246
V + ++++ +TL + H K +++ E ++ E+K F+ +E +++A+ ++ + K
Sbjct: 891 VELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKEKKLKAERDKSIELQKNAM 950
Query: 247 EQLQAKNRELLKQAAALSKSKKSE 270
E+L + + +Q A+ ++ ++E
Sbjct: 951 EKLHSMDDAFKRQVDAIVEAHQAE 974
Score = 33.9 bits (76), Expect = 0.16
Identities = 25/74 (33%), Positives = 41/74 (55%), Gaps = 9/74 (12%)
Query: 188 IIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTE 247
II E + LK L +KD+ I ++KITE++ + + Q+ K +Q++ EV E
Sbjct: 818 IIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIE---KCTQEQLDEKSSQLD----EVLE 870
Query: 248 QLQAKN--RELLKQ 259
+L+ N +E LKQ
Sbjct: 871 KLERHNERKEKLKQ 884
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 39.3 bits (90), Expect = 0.004
Identities = 25/94 (26%), Positives = 50/94 (53%), Gaps = 10/94 (10%)
Query: 191 QLKEEVATLKKMLHQKDQMILE------KEKKITEL----KADFQYQESQMRAKMNQMEK 240
+++ V L+K+ +K+ ++ E K K+++ K++F+ + + +A + +EK
Sbjct: 833 RIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEK 892
Query: 241 THKEVTEQLQAKNRELLKQAAALSKSKKSEKSGA 274
T KE+ QLQ + LK+ L KS + EK +
Sbjct: 893 TCKELKHQLQVQMENTLKEQKELKKSLEKEKEAS 926
Score = 34.7 bits (78), Expect = 0.094
Identities = 30/144 (20%), Positives = 66/144 (45%), Gaps = 6/144 (4%)
Query: 132 YKRVLQKTKEQRKH---LSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVI 188
+K++ Q+ +E+ +H L S H + + R G H D
Sbjct: 395 FKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQ 454
Query: 189 IAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMR---AKMNQMEKTHKEV 245
+A L+ +++ L++ L +K E + ++ + K Q Q++ + AK+ + + ++V
Sbjct: 455 VADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQV 514
Query: 246 TEQLQAKNRELLKQAAALSKSKKS 269
Q+ K++++ A L KSK++
Sbjct: 515 LRQIGDKDQKIQNLEALLQKSKEN 538
Score = 33.1 bits (74), Expect = 0.27
Identities = 22/91 (24%), Positives = 52/91 (57%), Gaps = 10/91 (10%)
Query: 188 IIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQM---RAKMNQME----K 240
+I +LK ATL++ +K+Q + E+ K + +++ + +E ++ ++K+ ++E +
Sbjct: 1076 LIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCR 1135
Query: 241 THKEVT---EQLQAKNRELLKQAAALSKSKK 268
KE+T E+L++ E +K+ L +K+
Sbjct: 1136 QEKEITKLNEELKSHKLESIKEITNLKDAKQ 1166
Score = 30.8 bits (68), Expect = 1.4
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 8/80 (10%)
Query: 194 EEVATLKKMLHQ----KDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQL 249
E+VA LKK L Q D M LE+E++ +LK + + +SQ + E T ++ +L
Sbjct: 221 EDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASS----EATISQLRSEL 276
Query: 250 QAKNRELLKQAAALSKSKKS 269
+E+ L K K S
Sbjct: 277 AKGPQEVAVYVQELQKLKSS 296
Score = 30.0 bits (66), Expect = 2.3
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Query: 190 AQLKEEVATLKKMLHQ---KDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKE-- 244
A+L+E L+++L Q KDQ I E + + K + E + +++ E
Sbjct: 502 AKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETA 561
Query: 245 VTEQLQAKNRELLKQAAALSKSKKSE 270
V QLQ KN L +Q L++ K++
Sbjct: 562 VLNQLQEKNHTLQEQVTQLTEKLKNQ 587
Score = 30.0 bits (66), Expect = 2.3
Identities = 19/81 (23%), Positives = 43/81 (53%), Gaps = 13/81 (16%)
Query: 191 QLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQ 250
QLK E+ ++++ L Q + + EK +E Q++ +N+++++ ++ +Q++
Sbjct: 928 QLKLELNSMQEQLIQAQNTLKQNEK-----------EEQQLQGNINELKQSSEQKKKQIE 976
Query: 251 AKNRELLKQAAALSKSKKSEK 271
A EL + A L K++ K
Sbjct: 977 ALQGEL--KIAVLQKTELENK 995
Score = 29.6 bits (65), Expect = 3.0
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 8/78 (10%)
Query: 189 IAQLKEEVATLKKMLHQKDQMILEKEK-------KITELKADFQYQESQMRAKMNQMEKT 241
I L E + T+KK + + E EK +I L+A Q + + RA + + K
Sbjct: 1243 ITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKG 1302
Query: 242 HKEVTEQLQAKNRELLKQ 259
E+ E+LQ K EL ++
Sbjct: 1303 EGEI-EKLQTKVLELQRK 1319
Score = 28.9 bits (63), Expect = 5.2
Identities = 31/130 (23%), Positives = 57/130 (43%), Gaps = 7/130 (5%)
Query: 132 YKRVLQKTKE---QRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVI 188
Y + QKT+E Q K L + S KEQ L + DL L + T+
Sbjct: 718 YLSLEQKTEELEGQIKKLEADSLEVKASKEQ--ALQDLQQQRQLNTDLELRA--TELSKQ 773
Query: 189 IAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQ 248
+ KE V++ + L +K + + ++K+T+ + + Q + + + H+E+ +
Sbjct: 774 LEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNR 833
Query: 249 LQAKNRELLK 258
+Q EL K
Sbjct: 834 IQTTVTELQK 843
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 38.9 bits (89), Expect = 0.005
Identities = 41/137 (29%), Positives = 58/137 (42%), Gaps = 12/137 (8%)
Query: 132 YKRVLQKT-KEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPD-LALDSPGTDHFVII 189
Y +VL +T E+ ++S G K + SG +S D LA D +
Sbjct: 313 YSKVLCQTLSERNSEITSLKNEGENLKRDNAITSG--MVSSLQKDILAKDEQ-------V 363
Query: 190 AQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQL 249
QLKEEV+ LK KD + + + LK + + QE R EK K Q+
Sbjct: 364 QQLKEEVSHLKSQNKDKDHQLEALGSRCSVLKEELK-QEDAHRELREAQEKELKLCKTQI 422
Query: 250 QAKNRELLKQAAALSKS 266
Q +E+ K A L KS
Sbjct: 423 QDMEKEMKKLRAELRKS 439
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 38.5 bits (88), Expect = 0.007
Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 11/82 (13%)
Query: 193 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAK 252
KEE+ + ++ + + I+E+EKK ELK K+ +K E+ EQ+ K
Sbjct: 321 KEEIQEKETIIEELNTKIIEEEKKTLELKD-----------KLTTADKLLGELQEQIVQK 369
Query: 253 NRELLKQAAALSKSKKSEKSGA 274
N+E+ L+ SK+ E+ +
Sbjct: 370 NQEIKNMKLELTNSKQKERQSS 391
Score = 31.2 bits (69), Expect = 1.0
Identities = 15/65 (23%), Positives = 37/65 (56%), Gaps = 1/65 (1%)
Query: 191 QLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQ 250
+LK+++ T K+L + + I++K ++I +K + + + R ++++ V E+LQ
Sbjct: 347 ELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTV-EELQ 405
Query: 251 AKNRE 255
+N +
Sbjct: 406 KRNHK 410
Score = 30.8 bits (68), Expect = 1.4
Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 3/77 (3%)
Query: 193 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAK 252
K E TL+ QK+ IL +E+K K + + +++ K +EK KE LQ K
Sbjct: 713 KSEEMTLQINELQKEIEILRQEEKE---KGTLEQEVQELQLKTELLEKQMKEKENDLQEK 769
Query: 253 NRELLKQAAALSKSKKS 269
+L + + L KK+
Sbjct: 770 FAQLEAENSILKDEKKT 786
Score = 30.0 bits (66), Expect = 2.3
Identities = 34/142 (23%), Positives = 63/142 (44%), Gaps = 22/142 (15%)
Query: 136 LQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPD---------LALDSPGTDHF 186
LQK E++ + S+ + ++Y++ S P+ L D G+D
Sbjct: 2543 LQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGSDIS 2602
Query: 187 VI---IAQLKEEVATLK-KMLHQKDQM------ILEKEKKITELKADFQYQESQMRAKMN 236
+ I++L+ +V + ++ +K+Q+ +LEKEKK+ EL+ + E + R K
Sbjct: 2603 ALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEK 2662
Query: 237 QMEKTHKEV---TEQLQAKNRE 255
+ EV T +L N E
Sbjct: 2663 KRSPQDVEVLKTTTELFHSNEE 2684
Score = 29.3 bits (64), Expect = 4.0
Identities = 19/84 (22%), Positives = 37/84 (44%), Gaps = 2/84 (2%)
Query: 189 IAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQ 248
I + K+ V T+ + + KD+ + ++ E+ Q+ Q+E +E+ Q
Sbjct: 1538 IPESKDCVLTISEEMFSKDKTFIVRQSIHDEISVSSMDASRQLMLNEEQLEDMRQELVRQ 1597
Query: 249 LQAKNR--ELLKQAAALSKSKKSE 270
Q + ELL+QA ++ E
Sbjct: 1598 YQEHQQATELLRQAHMRQMERQRE 1621
Score = 28.5 bits (62), Expect = 6.8
Identities = 21/95 (22%), Positives = 51/95 (53%), Gaps = 10/95 (10%)
Query: 186 FVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQM------RAKMNQME 239
F++ + +E++ + M + M+ E++ + + QYQE Q +A M QME
Sbjct: 1559 FIVRQSIHDEIS-VSSMDASRQLMLNEEQLEDMRQELVRQYQEHQQATELLRQAHMRQME 1617
Query: 240 KTHKE---VTEQLQAKNRELLKQAAALSKSKKSEK 271
+ ++ + E+++ NR+L ++++ +++ SE+
Sbjct: 1618 RQREDQEQLQEEIKRLNRQLAQRSSIDNENLVSER 1652
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 38.5 bits (88), Expect = 0.007
Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 11/82 (13%)
Query: 193 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAK 252
KEE+ + ++ + + I+E+EKK ELK K+ +K E+ EQ+ K
Sbjct: 321 KEEIQEKETIIEELNTKIIEEEKKTLELKD-----------KLTTADKLLGELQEQIVQK 369
Query: 253 NRELLKQAAALSKSKKSEKSGA 274
N+E+ L+ SK+ E+ +
Sbjct: 370 NQEIKNMKLELTNSKQKERQSS 391
Score = 31.2 bits (69), Expect = 1.0
Identities = 15/65 (23%), Positives = 37/65 (56%), Gaps = 1/65 (1%)
Query: 191 QLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQ 250
+LK+++ T K+L + + I++K ++I +K + + + R ++++ V E+LQ
Sbjct: 347 ELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTV-EELQ 405
Query: 251 AKNRE 255
+N +
Sbjct: 406 KRNHK 410
Score = 30.8 bits (68), Expect = 1.4
Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 3/77 (3%)
Query: 193 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAK 252
K E TL+ QK+ IL +E+K K + + +++ K +EK KE LQ K
Sbjct: 713 KSEEMTLQINELQKEIEILRQEEKE---KGTLEQEVQELQLKTELLEKQMKEKENDLQEK 769
Query: 253 NRELLKQAAALSKSKKS 269
+L + + L KK+
Sbjct: 770 FAQLEAENSILKDEKKT 786
Score = 30.0 bits (66), Expect = 2.3
Identities = 34/142 (23%), Positives = 63/142 (44%), Gaps = 22/142 (15%)
Query: 136 LQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPD---------LALDSPGTDHF 186
LQK E++ + S+ + ++Y++ S P+ L D G+D
Sbjct: 2535 LQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGSDIS 2594
Query: 187 VI---IAQLKEEVATLK-KMLHQKDQM------ILEKEKKITELKADFQYQESQMRAKMN 236
+ I++L+ +V + ++ +K+Q+ +LEKEKK+ EL+ + E + R K
Sbjct: 2595 ALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEK 2654
Query: 237 QMEKTHKEV---TEQLQAKNRE 255
+ EV T +L N E
Sbjct: 2655 KRSPQDVEVLKTTTELFHSNEE 2676
Score = 29.3 bits (64), Expect = 4.0
Identities = 19/84 (22%), Positives = 37/84 (44%), Gaps = 2/84 (2%)
Query: 189 IAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQ 248
I + K+ V T+ + + KD+ + ++ E+ Q+ Q+E +E+ Q
Sbjct: 1538 IPESKDCVLTISEEMFSKDKTFIVRQSIHDEISVSSMDASRQLMLNEEQLEDMRQELVRQ 1597
Query: 249 LQAKNR--ELLKQAAALSKSKKSE 270
Q + ELL+QA ++ E
Sbjct: 1598 YQEHQQATELLRQAHMRQMERQRE 1621
Score = 28.5 bits (62), Expect = 6.8
Identities = 21/95 (22%), Positives = 51/95 (53%), Gaps = 10/95 (10%)
Query: 186 FVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQM------RAKMNQME 239
F++ + +E++ + M + M+ E++ + + QYQE Q +A M QME
Sbjct: 1559 FIVRQSIHDEIS-VSSMDASRQLMLNEEQLEDMRQELVRQYQEHQQATELLRQAHMRQME 1617
Query: 240 KTHKE---VTEQLQAKNRELLKQAAALSKSKKSEK 271
+ ++ + E+++ NR+L ++++ +++ SE+
Sbjct: 1618 RQREDQEQLQEEIKRLNRQLAQRSSIDNENLVSER 1652
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 38.5 bits (88), Expect = 0.007
Identities = 46/239 (19%), Positives = 97/239 (40%), Gaps = 10/239 (4%)
Query: 44 EYQQESKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQ 103
E ++E + + KK Q + QY +++ + QR N Q
Sbjct: 191 ELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQ 250
Query: 104 CKQQCAFDRKDDRKKVDGKLLC--WLCTLSYKRVLQKTKEQRKHLSSSSRAGHQEKEQYS 161
+ Q K++ + DG+ + + + + Q+ K Q L KEQ +
Sbjct: 251 LEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCT 310
Query: 162 RLSGGGHYNSFSPDLAL-------DSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKE 214
L+ D L D + +I QL++ ++++ K +I E +
Sbjct: 311 LLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETK 370
Query: 215 KKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQ-AAALSKSKKSEKS 272
+++ E + + +Q+R+++ QM +E+ EQ + R ++ ALS ++K+E++
Sbjct: 371 RQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEA 429
Score = 32.3 bits (72), Expect = 0.47
Identities = 21/86 (24%), Positives = 45/86 (52%), Gaps = 7/86 (8%)
Query: 178 LDSPGTDHFVIIAQ----LKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMR- 232
+DS +H V I + LK+++ L+ +L ++D+ + E + + L+AD + E +++
Sbjct: 736 VDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQ 795
Query: 233 --AKMNQMEKTHKEVTEQLQAKNREL 256
AK++ + EQ +A +L
Sbjct: 796 ASAKLDVFQSYQSATHEQTKAYEEQL 821
Score = 32.3 bits (72), Expect = 0.47
Identities = 44/163 (26%), Positives = 69/163 (42%), Gaps = 26/163 (15%)
Query: 118 KVDGKLLCWLCTLSY--KRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPD 175
KV LL CT+S ++ Q T+EQ S +A HQ +E+ +++ S D
Sbjct: 1259 KVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIK------SMKAD 1312
Query: 176 LALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKM 235
I L E L+K + Q EKE IT+LK + S+ +
Sbjct: 1313 -------------IESLVTEKEALQKEGGNQQQAASEKESCITQLKKEL----SENINAV 1355
Query: 236 NQMEKTHKEVTEQLQAKNRELLKQAAALSKS-KKSEKSGAITS 277
M++ KE ++ + +++L L S SEK AI+S
Sbjct: 1356 TLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISS 1398
Score = 30.8 bits (68), Expect = 1.4
Identities = 22/91 (24%), Positives = 45/91 (49%), Gaps = 6/91 (6%)
Query: 191 QLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTH---KEVTE 247
+L +++ +++ +KD + E E+KI L+ ++++ K ++E + K E
Sbjct: 1561 ELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEE 1620
Query: 248 QLQAKNRELLKQAAAL---SKSKKSEKSGAI 275
+L+A L ++AA K K +K AI
Sbjct: 1621 ELKALEDRLESESAAKLAELKRKAEQKIAAI 1651
Score = 28.1 bits (61), Expect = 8.8
Identities = 13/76 (17%), Positives = 38/76 (50%)
Query: 183 TDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTH 242
T H + +L+ ++ K ++KD+ I ++++ + F + +M ++MEK
Sbjct: 1454 TQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKE 1513
Query: 243 KEVTEQLQAKNRELLK 258
+ +L+++ +++
Sbjct: 1514 SNLETELKSQTARIME 1529
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 38.1 bits (87), Expect = 0.009
Identities = 35/142 (24%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
Query: 133 KRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVI---I 189
++ L+K KE K + A +++E+ R +S S D +F++ I
Sbjct: 384 RKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEM-FGNFMLKRDI 442
Query: 190 AQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQL 249
A LKEE+ +K +K++ +++ K ITE+ A+F E +R + K + ++QL
Sbjct: 443 AMLKEELYAIKNDSLRKEKKYIQEIKSITEINANF---EKSVRLNEEMITKKVAQYSQQL 499
Query: 250 QAKNRELLKQAAALSKSKKSEK 271
E + + L K K +++
Sbjct: 500 NDLKAENARLNSKLEKEKHNKE 521
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 38.1 bits (87), Expect = 0.009
Identities = 35/142 (24%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
Query: 133 KRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVI---I 189
++ L+K KE K + A +++E+ R +S S D +F++ I
Sbjct: 413 RKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEM-FGNFMLKRDI 471
Query: 190 AQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQL 249
A LKEE+ +K +K++ +++ K ITE+ A+F E +R + K + ++QL
Sbjct: 472 AMLKEELYAIKNDSLRKEKKYIQEIKSITEINANF---EKSVRLNEEMITKKVAQYSQQL 528
Query: 250 QAKNRELLKQAAALSKSKKSEK 271
E + + L K K +++
Sbjct: 529 NDLKAENARLNSKLEKEKHNKE 550
>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1139
Score = 38.1 bits (87), Expect = 0.009
Identities = 35/142 (24%), Positives = 67/142 (47%), Gaps = 7/142 (4%)
Query: 133 KRVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVI---I 189
++ L+K KE K + A +++E+ R +S S D +F++ I
Sbjct: 413 RKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEM-FGNFMLKRDI 471
Query: 190 AQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQL 249
A LKEE+ +K +K++ +++ K ITE+ A+F E +R + K + ++QL
Sbjct: 472 AMLKEELYAIKNDSLRKEKKYIQEIKSITEINANF---EKSVRLNEEMITKKVAQYSQQL 528
Query: 250 QAKNRELLKQAAALSKSKKSEK 271
E + + L K K +++
Sbjct: 529 NDLKAENARLNSKLEKEKHNKE 550
>gi|14195601 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform b [Homo sapiens]
Length = 998
Score = 38.1 bits (87), Expect = 0.009
Identities = 28/106 (26%), Positives = 58/106 (54%), Gaps = 15/106 (14%)
Query: 179 DSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRA---KM 235
+S T++ + +L+E L + + +++ +K++K ++ + + ++ + RA KM
Sbjct: 887 ESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKM 946
Query: 236 NQMEK------------THKEVTEQLQAKNRELLKQAAALSKSKKS 269
++ME+ T K++ EQLQA+NR L + A LS+S +S
Sbjct: 947 SEMEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIES 992
>gi|14195599 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform d [Homo sapiens]
Length = 224
Score = 38.1 bits (87), Expect = 0.009
Identities = 28/106 (26%), Positives = 58/106 (54%), Gaps = 15/106 (14%)
Query: 179 DSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRA---KM 235
+S T++ + +L+E L + + +++ +K++K ++ + + ++ + RA KM
Sbjct: 113 ESALTENQKLKTKLQEAQLELADIKSKLEKVAQQKQEKTSDRSSVLEMEKRERRALERKM 172
Query: 236 NQMEK------------THKEVTEQLQAKNRELLKQAAALSKSKKS 269
++ME+ T K++ EQLQA+NR L + A LS+S +S
Sbjct: 173 SEMEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRVVARLSESIES 218
>gi|57768564 hypothetical protein LOC23281 isoform b [Homo sapiens]
Length = 348
Score = 38.1 bits (87), Expect = 0.009
Identities = 27/90 (30%), Positives = 46/90 (51%), Gaps = 17/90 (18%)
Query: 192 LKEEVATLKKMLHQKDQMILEKEKKITELK-------------ADFQYQESQMRAKMNQM 238
L+E++ +LK++L K+Q I E+EKKI EL+ Q Q ++A+++Q
Sbjct: 214 LEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQ- 272
Query: 239 EKTHKEVTEQLQAKNRELLKQAAALSKSKK 268
+ VT QL +N L + ++ KK
Sbjct: 273 ---NTVVTRQLSEENANLQEYVEKETQEKK 299
>gi|140161498 hypothetical protein LOC23281 isoform a [Homo sapiens]
Length = 1379
Score = 38.1 bits (87), Expect = 0.009
Identities = 27/90 (30%), Positives = 46/90 (51%), Gaps = 17/90 (18%)
Query: 192 LKEEVATLKKMLHQKDQMILEKEKKITELK-------------ADFQYQESQMRAKMNQM 238
L+E++ +LK++L K+Q I E+EKKI EL+ Q Q ++A+++Q
Sbjct: 1245 LEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQ- 1303
Query: 239 EKTHKEVTEQLQAKNRELLKQAAALSKSKK 268
+ VT QL +N L + ++ KK
Sbjct: 1304 ---NTVVTRQLSEENANLQEYVEKETQEKK 1330
>gi|27436948 lamin A/C isoform 3 [Homo sapiens]
Length = 634
Score = 37.4 bits (85), Expect = 0.015
Identities = 28/123 (22%), Positives = 55/123 (44%), Gaps = 4/123 (3%)
Query: 134 RVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVIIAQLK 193
+V Q KE K S+ Q E+ S L G H + +DS ++QL+
Sbjct: 255 QVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQ----LSQLQ 310
Query: 194 EEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKN 253
+++A + L + + + L A+ + + ++MRA+M Q ++E+ + A +
Sbjct: 311 KQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALD 370
Query: 254 REL 256
E+
Sbjct: 371 MEI 373
>gi|5031875 lamin A/C isoform 2 [Homo sapiens]
Length = 572
Score = 37.4 bits (85), Expect = 0.015
Identities = 28/123 (22%), Positives = 55/123 (44%), Gaps = 4/123 (3%)
Query: 134 RVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVIIAQLK 193
+V Q KE K S+ Q E+ S L G H + +DS ++QL+
Sbjct: 255 QVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQ----LSQLQ 310
Query: 194 EEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKN 253
+++A + L + + + L A+ + + ++MRA+M Q ++E+ + A +
Sbjct: 311 KQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALD 370
Query: 254 REL 256
E+
Sbjct: 371 MEI 373
>gi|27436946 lamin A/C isoform 1 precursor [Homo sapiens]
Length = 664
Score = 37.4 bits (85), Expect = 0.015
Identities = 28/123 (22%), Positives = 55/123 (44%), Gaps = 4/123 (3%)
Query: 134 RVLQKTKEQRKHLSSSSRAGHQEKEQYSRLSGGGHYNSFSPDLALDSPGTDHFVIIAQLK 193
+V Q KE K S+ Q E+ S L G H + +DS ++QL+
Sbjct: 255 QVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQ----LSQLQ 310
Query: 194 EEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKN 253
+++A + L + + + L A+ + + ++MRA+M Q ++E+ + A +
Sbjct: 311 KQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALD 370
Query: 254 REL 256
E+
Sbjct: 371 MEI 373
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 37.4 bits (85), Expect = 0.015
Identities = 18/67 (26%), Positives = 43/67 (64%), Gaps = 1/67 (1%)
Query: 189 IAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQ 248
I + +E++ ++M+ ++++ + E+E+K+ E + + Q QE +MR + ++ + K++ EQ
Sbjct: 392 IREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQ 451
Query: 249 LQAKNRE 255
+ K RE
Sbjct: 452 -EEKIRE 457
Score = 37.4 bits (85), Expect = 0.015
Identities = 19/67 (28%), Positives = 42/67 (62%), Gaps = 1/67 (1%)
Query: 189 IAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQ 248
I + +E++ ++M+ ++++ + E+E K+ E +A Q QE +MR + ++ + K++ EQ
Sbjct: 448 IREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQ 507
Query: 249 LQAKNRE 255
+ K RE
Sbjct: 508 -EEKIRE 513
Score = 33.9 bits (76), Expect = 0.16
Identities = 18/79 (22%), Positives = 44/79 (55%), Gaps = 3/79 (3%)
Query: 193 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQ---L 249
+EE+ ++ + ++++ I E+EKKI E + + QE M+ + +M + ++ EQ +
Sbjct: 424 EEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKM 483
Query: 250 QAKNRELLKQAAALSKSKK 268
Q + ++ +Q + + +K
Sbjct: 484 QEQEEKMRRQEEKIREQEK 502
Score = 33.9 bits (76), Expect = 0.16
Identities = 17/65 (26%), Positives = 39/65 (60%), Gaps = 3/65 (4%)
Query: 189 IAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMR---AKMNQMEKTHKEV 245
I + +E++ ++M+ ++++ + E+E+K+ E + Q QE +MR KM + E ++
Sbjct: 504 IREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQ 563
Query: 246 TEQLQ 250
E++Q
Sbjct: 564 EEKMQ 568
Score = 33.1 bits (74), Expect = 0.27
Identities = 15/76 (19%), Positives = 44/76 (57%)
Query: 193 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAK 252
+E++ L++ +H+++++ ++EK+ E K Q + + AKM + E+ +E E+++ +
Sbjct: 343 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 402
Query: 253 NRELLKQAAALSKSKK 268
+ +Q + + ++
Sbjct: 403 EEMMQEQEEKMGEQEE 418
Score = 32.0 bits (71), Expect = 0.61
Identities = 15/67 (22%), Positives = 42/67 (62%), Gaps = 1/67 (1%)
Query: 189 IAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQ 248
I + ++++ ++ + ++++M+ E+E+K+ E + QE++M+ + +M + +++ EQ
Sbjct: 441 IREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQ 500
Query: 249 LQAKNRE 255
+ K RE
Sbjct: 501 -EKKIRE 506
Score = 30.8 bits (68), Expect = 1.4
Identities = 16/71 (22%), Positives = 37/71 (52%)
Query: 200 KKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAKNRELLKQ 259
++ + ++++ I E+EKKI E + + QE M+ + +M + +++ EQ + + K
Sbjct: 487 EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 546
Query: 260 AAALSKSKKSE 270
K ++ E
Sbjct: 547 RRQEEKMREQE 557
Score = 29.6 bits (65), Expect = 3.0
Identities = 20/81 (24%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Query: 191 QLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMR---AKMNQMEKTHKEVTE 247
Q +E++ +K Q+ +M +E+KI E + + QE M+ KM + E+ E E
Sbjct: 367 QEEEKIREQEKRQEQEAKM-WRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEE 425
Query: 248 QLQAKNRELLKQAAALSKSKK 268
++Q + ++ +Q + + +K
Sbjct: 426 EMQEQEEKMRRQEEKIREQEK 446
Score = 29.3 bits (64), Expect = 4.0
Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 7/78 (8%)
Query: 200 KKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQM-EKTHK-----EVTEQLQAKN 253
+KM Q+++ I E+E+KI E + + QE +MR + M EK K E+ + + K
Sbjct: 288 EKMWRQEEK-IQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 346
Query: 254 RELLKQAAALSKSKKSEK 271
REL ++ K ++ E+
Sbjct: 347 RELEEKMHEQEKIREQEE 364
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 37.0 bits (84), Expect = 0.019
Identities = 19/81 (23%), Positives = 49/81 (60%), Gaps = 7/81 (8%)
Query: 193 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAK 252
+E++ ++ + ++++ + E+E+++ + + Q QE QMR + QM +E EQ++ +
Sbjct: 219 EEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM----REQEEQMREQ 274
Query: 253 NRELLKQAAALSKSKKSEKSG 273
++LKQ ++++ E++G
Sbjct: 275 EEQMLKQK---EQTEQEEQTG 292
Score = 33.1 bits (74), Expect = 0.27
Identities = 16/79 (20%), Positives = 44/79 (55%), Gaps = 3/79 (3%)
Query: 193 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHK---EVTEQL 249
KE++ ++ + ++++ + ++E+++ + + + QE QMR + QM K + E EQ+
Sbjct: 344 KEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQM 403
Query: 250 QAKNRELLKQAAALSKSKK 268
+ ++ +Q + + K+
Sbjct: 404 GEQKEQMREQEEQMGEQKE 422
Score = 32.7 bits (73), Expect = 0.36
Identities = 17/76 (22%), Positives = 43/76 (56%), Gaps = 4/76 (5%)
Query: 193 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQLQAK 252
KE++ K+ + ++++ + E+E+++ + + + QE QMR + QM K EQ++ +
Sbjct: 337 KEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQE----EQMRKQ 392
Query: 253 NRELLKQAAALSKSKK 268
++ +Q + + K+
Sbjct: 393 EEQMGEQKEQMGEQKE 408
Score = 32.0 bits (71), Expect = 0.61
Identities = 21/79 (26%), Positives = 42/79 (53%), Gaps = 4/79 (5%)
Query: 193 KEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHK---EVTEQL 249
KE+ ++ Q++QM E+E+++ E + + QE QMR + QM K + E EQ+
Sbjct: 282 KEQTEQEEQTGEQEEQM-REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQM 340
Query: 250 QAKNRELLKQAAALSKSKK 268
+ ++ KQ + + ++
Sbjct: 341 WEQKEQMWKQEEQMGEQEE 359
Score = 30.0 bits (66), Expect = 2.3
Identities = 20/80 (25%), Positives = 41/80 (51%), Gaps = 6/80 (7%)
Query: 191 QLKEEVATLKKMLHQKDQ--MILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTEQ 248
Q++E+ + K Q +Q E+E+++ E + + QE QMR + QM +E EQ
Sbjct: 270 QMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQM----REQEEQ 325
Query: 249 LQAKNRELLKQAAALSKSKK 268
+ + ++ +Q + + K+
Sbjct: 326 MGKQEEQMWEQKEQMWEQKE 345
Score = 29.6 bits (65), Expect = 3.0
Identities = 19/66 (28%), Positives = 35/66 (53%), Gaps = 6/66 (9%)
Query: 189 IAQLKEEVATLKKMLHQKDQM------ILEKEKKITELKADFQYQESQMRAKMNQMEKTH 242
I +LK ++ T K L Q+ Q+ + E+E ++ E + + QE Q+R + Q+ +
Sbjct: 34 IKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 93
Query: 243 KEVTEQ 248
+V EQ
Sbjct: 94 GQVREQ 99
Score = 28.9 bits (63), Expect = 5.2
Identities = 21/96 (21%), Positives = 47/96 (48%), Gaps = 16/96 (16%)
Query: 189 IAQLKEEVATLKKMLHQKDQMILE-------------KEKKITELKADFQYQESQMRAKM 235
+ + +E+V ++ + ++++ + E K+K+ TE + QE QMR +
Sbjct: 243 VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQE 302
Query: 236 NQM---EKTHKEVTEQLQAKNRELLKQAAALSKSKK 268
QM E+ +E EQ++ + ++ KQ + + K+
Sbjct: 303 EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKE 338
Score = 28.5 bits (62), Expect = 6.8
Identities = 16/84 (19%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Query: 191 QLKEEVATLKKM---LHQKDQMILEKEKKITELKADFQYQESQMRAKMNQMEKTHKEVTE 247
Q++E+ +++ + +++ + E+E ++ E + QE QM + QM+K +++ E
Sbjct: 165 QVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGE 224
Query: 248 QLQAKNRELLKQAAALSKSKKSEK 271
Q + ++ + + +K E+
Sbjct: 225 QEEQMRKQEEQMGEQEEQVQKQEE 248
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.128 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,254,744
Number of Sequences: 37866
Number of extensions: 535804
Number of successful extensions: 4528
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 170
Number of HSP's successfully gapped in prelim test: 394
Number of HSP's that attempted gapping in prelim test: 3357
Number of HSP's gapped (non-prelim): 1555
length of query: 278
length of database: 18,247,518
effective HSP length: 101
effective length of query: 177
effective length of database: 14,423,052
effective search space: 2552880204
effective search space used: 2552880204
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.