Guide to the Human Genome
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Search of human proteins with 219842247

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|219842247 periphilin 1 isoform 7 [Homo sapiens]
         (348 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|219842247 periphilin 1 isoform 7 [Homo sapiens]                    713   0.0  
gi|41872344 periphilin 1 isoform 3 [Homo sapiens]                     700   0.0  
gi|41872368 periphilin 1 isoform 2 [Homo sapiens]                     700   0.0  
gi|48255929 periphilin 1 isoform 1 [Homo sapiens]                     645   0.0  
gi|219842250 periphilin 1 isoform 8 [Homo sapiens]                    545   e-155
gi|41872349 periphilin 1 isoform 4 [Homo sapiens]                     531   e-151
gi|219842244 periphilin 1 isoform 6 [Homo sapiens]                    476   e-134
gi|41872339 periphilin 1 isoform 5 [Homo sapiens]                     403   e-112
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          52   8e-07
gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]    48   1e-05
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]    47   3e-05
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2...    45   7e-05
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1...    45   7e-05
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  45   1e-04
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]     45   1e-04
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi...    44   2e-04
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...    44   3e-04
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]       43   4e-04
gi|38016935 MLF1 interacting protein [Homo sapiens]                    42   8e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        42   8e-04
gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]     42   0.001
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]     40   0.002
gi|34996489 pleckstrin homology domain interacting protein [Homo...    40   0.002
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]     39   0.005
gi|50083281 KIAA1853 protein [Homo sapiens]                            39   0.005
gi|24762236 PRP38 pre-mRNA processing factor 38 (yeast) domain c...    39   0.005
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]      39   0.007
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           39   0.009
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           39   0.009
gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens]          38   0.015

>gi|219842247 periphilin 1 isoform 7 [Homo sapiens]
          Length = 348

 Score =  713 bits (1841), Expect = 0.0
 Identities = 348/348 (100%), Positives = 348/348 (100%)

Query: 1   MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD 60
           MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD
Sbjct: 1   MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD 60

Query: 61  YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER 120
           YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER
Sbjct: 61  YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER 120

Query: 121 SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERPVQSLK 180
           SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERPVQSLK
Sbjct: 121 SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERPVQSLK 180

Query: 181 TSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGS 240
           TSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGS
Sbjct: 181 TSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGS 240

Query: 241 TAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQDCETFGMVVKML 300
           TAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQDCETFGMVVKML
Sbjct: 241 TAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQDCETFGMVVKML 300

Query: 301 IEKDPSLEKSIQFALRQNLHEIGERCVEELKHFIAEYDTSTQDFGEPF 348
           IEKDPSLEKSIQFALRQNLHEIGERCVEELKHFIAEYDTSTQDFGEPF
Sbjct: 301 IEKDPSLEKSIQFALRQNLHEIGERCVEELKHFIAEYDTSTQDFGEPF 348


>gi|41872344 periphilin 1 isoform 3 [Homo sapiens]
          Length = 367

 Score =  700 bits (1806), Expect = 0.0
 Identities = 347/367 (94%), Positives = 348/367 (94%), Gaps = 19/367 (5%)

Query: 1   MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD 60
           MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD
Sbjct: 1   MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD 60

Query: 61  YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER 120
           YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER
Sbjct: 61  YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER 120

Query: 121 SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQH----------- 169
           SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQH           
Sbjct: 121 SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYK 180

Query: 170 --------RNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK 221
                   R+KERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK
Sbjct: 181 RQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK 240

Query: 222 LEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKE 281
           LEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKE
Sbjct: 241 LEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKE 300

Query: 282 IEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIGERCVEELKHFIAEYDTST 341
           IEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIGERCVEELKHFIAEYDTST
Sbjct: 301 IEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIGERCVEELKHFIAEYDTST 360

Query: 342 QDFGEPF 348
           QDFGEPF
Sbjct: 361 QDFGEPF 367


>gi|41872368 periphilin 1 isoform 2 [Homo sapiens]
          Length = 374

 Score =  700 bits (1806), Expect = 0.0
 Identities = 347/367 (94%), Positives = 348/367 (94%), Gaps = 19/367 (5%)

Query: 1   MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD 60
           MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD
Sbjct: 8   MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD 67

Query: 61  YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER 120
           YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER
Sbjct: 68  YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER 127

Query: 121 SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQH----------- 169
           SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQH           
Sbjct: 128 SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYK 187

Query: 170 --------RNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK 221
                   R+KERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK
Sbjct: 188 RQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK 247

Query: 222 LEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKE 281
           LEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKE
Sbjct: 248 LEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKE 307

Query: 282 IEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIGERCVEELKHFIAEYDTST 341
           IEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIGERCVEELKHFIAEYDTST
Sbjct: 308 IEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIGERCVEELKHFIAEYDTST 367

Query: 342 QDFGEPF 348
           QDFGEPF
Sbjct: 368 QDFGEPF 374


>gi|48255929 periphilin 1 isoform 1 [Homo sapiens]
          Length = 458

 Score =  645 bits (1663), Expect = 0.0
 Identities = 321/341 (94%), Positives = 322/341 (94%), Gaps = 19/341 (5%)

Query: 1   MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD 60
           MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD
Sbjct: 1   MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRD 60

Query: 61  YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER 120
           YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER
Sbjct: 61  YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER 120

Query: 121 SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQH----------- 169
           SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQH           
Sbjct: 121 SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYK 180

Query: 170 --------RNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK 221
                   R+KERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK
Sbjct: 181 RQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK 240

Query: 222 LEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKE 281
           LEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKE
Sbjct: 241 LEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKE 300

Query: 282 IEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEI 322
           IEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEI
Sbjct: 301 IEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEI 341


>gi|219842250 periphilin 1 isoform 8 [Homo sapiens]
          Length = 293

 Score =  545 bits (1403), Expect = e-155
 Identities = 273/280 (97%), Positives = 273/280 (97%), Gaps = 2/280 (0%)

Query: 71  RRSGPP--HRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 128
           R   PP  H  DESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT
Sbjct: 14  RERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 73

Query: 129 FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERPVQSLKTSRDTSPS 188
           FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERPVQSLKTSRDTSPS
Sbjct: 74  FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERPVQSLKTSRDTSPS 133

Query: 189 SGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQ 248
           SGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQ
Sbjct: 134 SGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQ 193

Query: 249 PEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQDCETFGMVVKMLIEKDPSLE 308
           PEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQDCETFGMVVKMLIEKDPSLE
Sbjct: 194 PEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQDCETFGMVVKMLIEKDPSLE 253

Query: 309 KSIQFALRQNLHEIGERCVEELKHFIAEYDTSTQDFGEPF 348
           KSIQFALRQNLHEIGERCVEELKHFIAEYDTSTQDFGEPF
Sbjct: 254 KSIQFALRQNLHEIGERCVEELKHFIAEYDTSTQDFGEPF 293


>gi|41872349 periphilin 1 isoform 4 [Homo sapiens]
          Length = 319

 Score =  531 bits (1368), Expect = e-151
 Identities = 272/299 (90%), Positives = 273/299 (91%), Gaps = 21/299 (7%)

Query: 71  RRSGPP--HRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 128
           R   PP  H  DESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT
Sbjct: 21  RERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 80

Query: 129 FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHR------------------ 170
           FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHR                  
Sbjct: 81  FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPE 140

Query: 171 -NKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 229
            +KERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN
Sbjct: 141 RDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 200

Query: 230 LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQD 289
           LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQD
Sbjct: 201 LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQD 260

Query: 290 CETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIGERCVEELKHFIAEYDTSTQDFGEPF 348
           CETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIGERCVEELKHFIAEYDTSTQDFGEPF
Sbjct: 261 CETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIGERCVEELKHFIAEYDTSTQDFGEPF 319


>gi|219842244 periphilin 1 isoform 6 [Homo sapiens]
          Length = 434

 Score =  476 bits (1225), Expect = e-134
 Identities = 246/273 (90%), Positives = 247/273 (90%), Gaps = 21/273 (7%)

Query: 71  RRSGPP--HRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 128
           R   PP  H  DESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT
Sbjct: 14  RERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 73

Query: 129 FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHR------------------ 170
           FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHR                  
Sbjct: 74  FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPE 133

Query: 171 -NKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 229
            +KERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN
Sbjct: 134 RDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 193

Query: 230 LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQD 289
           LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQD
Sbjct: 194 LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQD 253

Query: 290 CETFGMVVKMLIEKDPSLEKSIQFALRQNLHEI 322
           CETFGMVVKMLIEKDPSLEKSIQFALRQNLHEI
Sbjct: 254 CETFGMVVKMLIEKDPSLEKSIQFALRQNLHEI 286


>gi|41872339 periphilin 1 isoform 5 [Homo sapiens]
          Length = 258

 Score =  403 bits (1035), Expect = e-112
 Identities = 209/236 (88%), Positives = 210/236 (88%), Gaps = 21/236 (8%)

Query: 71  RRSGPP--HRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 128
           R   PP  H  DESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT
Sbjct: 21  RERAPPRSHPSDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 80

Query: 129 FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHR------------------ 170
           FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHR                  
Sbjct: 81  FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPE 140

Query: 171 -NKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 229
            +KERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN
Sbjct: 141 RDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 200

Query: 230 LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQV 285
           LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQV
Sbjct: 201 LPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQV 256


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 65/255 (25%), Positives = 95/255 (37%), Gaps = 24/255 (9%)

Query: 42  DRPGEGSYNRYYSHVDYRDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRD 101
           DR    S N+   H   R  ++ R  S  R         + G      DH  SR P  ++
Sbjct: 448 DRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPS-KE 506

Query: 102 MRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSV----SSRSYSPE 157
            +    R S     + R RSP K        SP   +D   SRS S       SRS S E
Sbjct: 507 RQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKE 566

Query: 158 R--------SKSYSFHQSQHRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKE 209
           R        SK     QS+  ++ER     ++    S  S    SS +     SR   KE
Sbjct: 567 RDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKE 626

Query: 210 LAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELF------ 263
              + S+ ++++ + S +S +P   +++   T      Q   P   ++H    F      
Sbjct: 627 GNHSQSRTSSKESDPS-QSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQT 685

Query: 264 ---EDSQL-TTRSKA 274
              +DSQ   T SKA
Sbjct: 686 LSQDDSQADATTSKA 700



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 57/208 (27%), Positives = 80/208 (38%), Gaps = 27/208 (12%)

Query: 54  SHVDYRDYDEGRSFSHDRRSGPP--HRGD----------ESGYRWTRDDHSASRQPEYRD 101
           SH   R+  + RS SH R S     HRG           +SG    + DHS SR P    
Sbjct: 352 SHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPN--K 409

Query: 102 MRDGFRRKSFYSSH-------------YARERSPYKRDNTFFRESPVGRKDSPHSRSGSS 148
            RD  R +S Y +               +R RSPYK  +     SP   +D   SRS + 
Sbjct: 410 ARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNK 469

Query: 149 VSSRSYSPERSKSYSFHQSQHRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEK 208
              RS S   SK     Q    +KER  +  ++         S  SS +   + SR   K
Sbjct: 470 ARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSK 529

Query: 209 ELAEAASKWAAEKLEKSDESNLPEISEY 236
           E     S+   ++ ++S   +  E  E+
Sbjct: 530 ERQRRQSRSPNKERDRSQSRSPSEEREH 557



 Score = 33.1 bits (74), Expect = 0.38
 Identities = 41/176 (23%), Positives = 71/176 (40%), Gaps = 28/176 (15%)

Query: 48  SYNRYYSHVDYRDYDEGRSFSHDRRSGPPHRGDES--GYRWTRDDHSASRQPEYRDMRDG 105
           SYN+  +    + + + RS     RSG   R       + W R+ HS +R    + +   
Sbjct: 268 SYNQASTRSRPQSHSQSRS-PRRSRSGSQKRTHSRVRSHSWKRN-HSRARSRTRKGILSQ 325

Query: 106 FRRKSFYSSHYA-----RERSPYKRDNTFFRESPVGRKDSPHSRSGS------------- 147
             R S   SH       + R+P +  +  +  +P   +   HSRS S             
Sbjct: 326 MGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRK 385

Query: 148 -SVSSRSYSPERSKSYSFHQSQHRNKER-----PVQSLKTSRDTSPSSGSAVSSSK 197
            S  S+S SP + + +S  +S ++ ++R     P ++   SR  SP+     S S+
Sbjct: 386 ESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSR 441


>gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]
          Length = 282

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 53/169 (31%), Positives = 70/169 (41%), Gaps = 32/169 (18%)

Query: 65  RSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER---S 121
           RS S+ RRS  P R   S  R      S SR   YR  R  + R  +  S Y+R R   S
Sbjct: 117 RSRSYGRRSRSPRRRHRSRSRGPSCSRSRSRS-RYRGSR--YSRSPYSRSPYSRSRYSRS 173

Query: 122 PYKRDNTFFRESPVG-----------------RKDSPHSRSGSSVSSRSYSPERS----K 160
           PY R    +RES  G                      HS+SGSS SSRS S  +S    +
Sbjct: 174 PYSRSR--YRESRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKSSSARR 231

Query: 161 SYSFHQSQHRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKE 209
           S S   S+ R++ R     ++    S     + S SK   +P +  E+E
Sbjct: 232 SKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRSRSK---RPPKSPEEE 277



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 49/190 (25%), Positives = 66/190 (34%), Gaps = 21/190 (11%)

Query: 65  RSFSHDRRSGPPHRGDESGY-RWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPY 123
           R     R+  P  R    GY R +R     SR P  R       R    S   +R RS Y
Sbjct: 95  RDLPRSRQGEPRGRSRGGGYGRRSRSYGRRSRSPRRRHRS----RSRGPSCSRSRSRSRY 150

Query: 124 KRDNTFFRESPVGRKDSPHSRSGSSVSSRS-YSPER-------SKSYS------FHQSQH 169
           +     +  SP  R     SR   S  SRS Y   R       S  YS      +H S+ 
Sbjct: 151 RGSR--YSRSPYSRSPYSRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNSRYSRYHSSRS 208

Query: 170 RNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 229
            +K     S +++  +  SS     SS V    SR     +  +  + +  K +    S 
Sbjct: 209 HSKSGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRSRSK 268

Query: 230 LPEISEYEAG 239
            P  S  E G
Sbjct: 269 RPPKSPEEEG 278



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 53/199 (26%), Positives = 71/199 (35%), Gaps = 16/199 (8%)

Query: 6   RYEYERIPRER-APPRSHP-SDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRDYDE 63
           RY    +PR R   PR      GY R       +     R       R+ S         
Sbjct: 91  RYGRRDLPRSRQGEPRGRSRGGGYGR-------RSRSYGRRSRSPRRRHRSRSRGPSCSR 143

Query: 64  GRSFSHDRRS----GPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYAR- 118
            RS S  R S     P  R   S  R++R  +S SR  E R     +    + +S Y+R 
Sbjct: 144 SRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNSRYSRY 203

Query: 119 --ERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERPV 176
              RS  K  ++    S    K S   RS SS  SRS S  RS S +    +   ++   
Sbjct: 204 HSSRSHSKSGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKS 263

Query: 177 QSLKTSRDTSPSSGSAVSS 195
           +S       SP     +SS
Sbjct: 264 RSRSKRPPKSPEEEGQMSS 282


>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
          Length = 1462

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 42/177 (23%), Positives = 77/177 (43%), Gaps = 2/177 (1%)

Query: 113 SSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNK 172
           SS++ RE++     +T+ + S    + SP SRS SS  SRSYS   ++S S   S  R++
Sbjct: 662 SSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSS-RSRSYSRSYTRSRSLASSHSRSR 720

Query: 173 ERPVQSLKTSRDTSPSSGSAVSS-SKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLP 231
               +S   ++ +  S  S  SS + +     R  ++ L  +  K +    + S  S   
Sbjct: 721 SPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKT 780

Query: 232 EISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQ 288
             S+Y  G        +  E  S+  +  +  + S   T+S     K  ++E+ + +
Sbjct: 781 LHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNK 837



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 41/174 (23%), Positives = 77/174 (44%), Gaps = 8/174 (4%)

Query: 92  SASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRD----NTFFRESPVGRKDSPHSRSGS 147
           S++R+ +    R+   R S  SSH++ +R   K D    ++    S    +   HS+S S
Sbjct: 470 SSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYS 529

Query: 148 SVSSRSYSPERSKSYSFHQSQHRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTE 207
             SSRS +  +S S+S  +S+ R+  +     + S+    ++     +  V  +P R T 
Sbjct: 530 RGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATM 589

Query: 208 KELAE-AASKWAAEKLEKSDESNLPEISEYEAGST--APLFTDQPEEPESNTTH 258
            +          AE +     S+ P  S ++ G     P + ++ +E ++ TTH
Sbjct: 590 AQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSY-ERIQEMKAKTTH 642



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 40/130 (30%), Positives = 46/130 (35%), Gaps = 22/130 (16%)

Query: 48   SYNRYYSHVDYRDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFR 107
            S +R  S    R      S+SH R      R   S YR      S SR           R
Sbjct: 1315 SRSRSKSETKSRHRTRSVSYSHSRSRS---RSSTSSYR----SRSYSRS----------R 1357

Query: 108  RKSFYSSHYARERSP----YKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYS 163
             + +YS    R RS     YK   T  R         PHSRS S      YS  RS+S S
Sbjct: 1358 SRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRS 1417

Query: 164  FH-QSQHRNK 172
                S HR +
Sbjct: 1418 QRSDSYHRGR 1427



 Score = 30.0 bits (66), Expect = 3.2
 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 5/98 (5%)

Query: 151  SRSYSPERSKSYSFHQSQHRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSR--LTEK 208
            S+S SP RS+S S  +S+HR +     S   SR  S SS S+  S       SR   +  
Sbjct: 1309 SQSRSPSRSRSKSETKSRHRTRS---VSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRG 1365

Query: 209  ELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFT 246
                 +S + + K  ++   +    S Y+  S +  +T
Sbjct: 1366 RTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYT 1403


>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
           [Homo sapiens]
          Length = 1481

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 70/250 (28%), Positives = 100/250 (40%), Gaps = 35/250 (14%)

Query: 10  ERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRDYDE---GRS 66
           E+  +ER     H     +      PK    +D P   S + +    D    D+   G S
Sbjct: 182 EKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGAS 241

Query: 67  FSHDRRSGPPHRGDESGY-RWTRDDHSASRQ----PEYRD---MRDGFRRKSFYS----- 113
           +  D    P      S Y  + +   S SR+    P Y++    +   R  S YS     
Sbjct: 242 YGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRS 301

Query: 114 -SHYARERSP-YKRDNTFFRESP--VGRKDSP------HSRSGSSVSSRSYSPERSKS-- 161
            S Y+R RS  Y+R  ++   SP   GR+ S        S S S + SR     RS+S  
Sbjct: 302 VSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPA 361

Query: 162 YSFHQSQHRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK 221
           YS H S H  K+R   S   SR +S S      +S +  + SR  +KE A AA   AA K
Sbjct: 362 YSRHSSSHSKKKR---SSSRSRHSSISPVRLPLNSSLGAELSR-KKKERAAAA---AAAK 414

Query: 222 LEKSDESNLP 231
           ++  +    P
Sbjct: 415 MDGKESKGSP 424



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 32/148 (21%), Positives = 54/148 (36%), Gaps = 8/148 (5%)

Query: 57  DYRDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHY 116
           D   + +  +F  DRR     RG +   R  +  H   R+   RD+    + +   S   
Sbjct: 79  DSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRS--RDLLKAKQTEKEKSQEV 136

Query: 117 ARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERPV 176
           + +    K      R S   ++ +  +           S + S+S   H+ + R KER +
Sbjct: 137 SSKSGSMKD-----RISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTR-KEREL 190

Query: 177 QSLKTSRDTSPSSGSAVSSSKVLDKPSR 204
           +S    R  S        S K +D P R
Sbjct: 191 KSGHKDRSKSHRKRETPKSYKTVDSPKR 218


>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
           [Homo sapiens]
          Length = 1490

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 70/250 (28%), Positives = 100/250 (40%), Gaps = 35/250 (14%)

Query: 10  ERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRDYDE---GRS 66
           E+  +ER     H     +      PK    +D P   S + +    D    D+   G S
Sbjct: 182 EKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGAS 241

Query: 67  FSHDRRSGPPHRGDESGY-RWTRDDHSASRQ----PEYRD---MRDGFRRKSFYS----- 113
           +  D    P      S Y  + +   S SR+    P Y++    +   R  S YS     
Sbjct: 242 YGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRS 301

Query: 114 -SHYARERSP-YKRDNTFFRESP--VGRKDSP------HSRSGSSVSSRSYSPERSKS-- 161
            S Y+R RS  Y+R  ++   SP   GR+ S        S S S + SR     RS+S  
Sbjct: 302 VSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPA 361

Query: 162 YSFHQSQHRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEK 221
           YS H S H  K+R   S   SR +S S      +S +  + SR  +KE A AA   AA K
Sbjct: 362 YSRHSSSHSKKKR---SSSRSRHSSISPVRLPLNSSLGAELSR-KKKERAAAA---AAAK 414

Query: 222 LEKSDESNLP 231
           ++  +    P
Sbjct: 415 MDGKESKGSP 424



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 32/148 (21%), Positives = 54/148 (36%), Gaps = 8/148 (5%)

Query: 57  DYRDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHY 116
           D   + +  +F  DRR     RG +   R  +  H   R+   RD+    + +   S   
Sbjct: 79  DSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRS--RDLLKAKQTEKEKSQEV 136

Query: 117 ARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERPV 176
           + +    K      R S   ++ +  +           S + S+S   H+ + R KER +
Sbjct: 137 SSKSGSMKD-----RISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTR-KEREL 190

Query: 177 QSLKTSRDTSPSSGSAVSSSKVLDKPSR 204
           +S    R  S        S K +D P R
Sbjct: 191 KSGHKDRSKSHRKRETPKSYKTVDSPKR 218


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 57/227 (25%), Positives = 83/227 (36%), Gaps = 48/227 (21%)

Query: 3   SEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRDYD 62
           ++G++ Y    RER+  R       +R  +         DR     Y+RY    +YR   
Sbjct: 552 TKGKHSYNSRTRERSRSRDRSRRVRSRTHD--------RDRSRSKEYHRYREQ-EYRR-- 600

Query: 63  EGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSP 122
            GRS S +RR+ P     +   R  RD  S+ R+      +D +R +   SSH       
Sbjct: 601 RGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSH------- 653

Query: 123 YKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERPVQSLKTS 182
                         RK++  S        R YS  R      H S + ++E+     K  
Sbjct: 654 --------------RKENSES------EKRMYSKSRD-----HNSSNNSREK-----KAD 683

Query: 183 RDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESN 229
           RD SP S    SS     K S L  KE  +  S    E  +   + N
Sbjct: 684 RDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQEN 730



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 73/301 (24%), Positives = 113/301 (37%), Gaps = 60/301 (19%)

Query: 14  RERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRDYDEGRSFSHDRRS 73
           RE  PP S P+    RL         L+ R G     R      YR     RS    RRS
Sbjct: 308 RECNPPNSQPASYQRRL---------LVTRSGRKIKGRGPRR--YRTPSRSRSRDRFRRS 356

Query: 74  G-PPHRGDE----------SGYRWTRDDHSA-------SRQP---------EYRDMRDGF 106
             PPH   E          SG RW + D S         R P         ++R++ +  
Sbjct: 357 ETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESP 416

Query: 107 RRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQ 166
            RK+       ++     ++    R S    K     +  +   SRS S E+SKS     
Sbjct: 417 NRKN-EKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDS 475

Query: 167 SQHRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLE-KS 225
             +RN+E+ ++S    RD          + K  +K S    K+   + SK  +++LE KS
Sbjct: 476 KHNRNEEKRMRSRSKGRDH--------ENVKEKEKQSDSKGKDQERSRSKEKSKQLESKS 527

Query: 226 DESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELF-----EDSQLTTRSKAIASKTK 280
           +E +  +  E +  +       Q    E + T G   +     E S+   RS+ + S+T 
Sbjct: 528 NEHDHSKSKEKDRRA-------QSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTH 580

Query: 281 E 281
           +
Sbjct: 581 D 581


>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
          Length = 494

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 66/235 (28%), Positives = 94/235 (40%), Gaps = 42/235 (17%)

Query: 7   YEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRDYDEGR- 65
           Y Y R  R++  P +     Y  +V  +  +    D      Y R    V Y D  +GR 
Sbjct: 86  YGYRRSGRDKYGPPTRTE--YRLIVENLSSRCSWQDLK---DYMRQAGEVTYADAHKGRK 140

Query: 66  --------SFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYA 117
                   S+S  +R+     G E   R  R            + + G RR+  YS    
Sbjct: 141 NEGVIEFVSYSDMKRALEKLDGTEVNGRKIR----------LVEDKPGSRRRRSYS---- 186

Query: 118 RERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERPVQ 177
           R RS + R  +  R S   R     SRSGSS SS S S  RS+S S  +S+ R++ +   
Sbjct: 187 RSRS-HSRSRSRSRHSRKSR-----SRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRS 240

Query: 178 SLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPE 232
             K  +  SPS   + S S    K SR   K+ AE       EK++ +D    P+
Sbjct: 241 RSKKEKSRSPSKEKSRSRSHSAGK-SRSKSKDQAE-------EKIQNNDNVGKPK 287



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 67/277 (24%), Positives = 111/277 (40%), Gaps = 26/277 (9%)

Query: 61  YDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARER 120
           Y  GRS    RRSG    G  +   +     + S +  ++D++D  R+    +  YA   
Sbjct: 79  YGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVT--YADAH 136

Query: 121 SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSY-------SPERSKSYSFHQSQHRNKE 173
              K +      S    K +     G+ V+ R            R +SYS  +S  R++ 
Sbjct: 137 KGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRS 196

Query: 174 RPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEI 233
           R   S K SR  S SS S+ S S+     SR   +  +++ S+  +    K ++S  P  
Sbjct: 197 RSRHSRK-SRSRSGSSKSSHSKSR---SRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSK 252

Query: 234 SE-----YEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQ 288
            +     + AG +     DQ EE   N  +  +    S    +SK   SK++   Q  R 
Sbjct: 253 EKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSK---SKSRSRSQERRV 309

Query: 289 DCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIGER 325
           + E  G V      +  S EKS++ +  ++  + G R
Sbjct: 310 EEEKRGSV-----SRGRSQEKSLRQSRSRSRSKGGSR 341



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 43/170 (25%), Positives = 64/170 (37%), Gaps = 20/170 (11%)

Query: 59  RDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYAR 118
           R Y   RS S  R      R   S    ++  HS SR       R G R +S   S  ++
Sbjct: 183 RSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRS----RSGSRSRSKSRSR-SQ 237

Query: 119 ERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERPVQS 178
            RS  K++                SRS S   SRS S    KS S  + Q   K +   +
Sbjct: 238 SRSRSKKEK---------------SRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDN 282

Query: 179 LKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDES 228
           +   +  SPS   + S S+   +  R+ E++    +   + EK  +   S
Sbjct: 283 VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRS 332



 Score = 32.7 bits (73), Expect = 0.49
 Identities = 55/233 (23%), Positives = 89/233 (38%), Gaps = 20/233 (8%)

Query: 3   SEGRYEYERIP-RERAPPRSHPSDGYNRLVNIVPKKPPL-----LDRPGEGSYNRYYSHV 56
           S  + E  R P +E++  RSH S G +R  +    +  +     + +P   S +R+ S  
Sbjct: 240 SRSKKEKSRSPSKEKSRSRSH-SAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS 298

Query: 57  DYRDYDEGRSFSHDRRSGPPH-RGDESGYRWTRD-------DHSASR-QPEYRDMRDGFR 107
             R   + R    ++R      R  E   R +R          S SR + + +D R G +
Sbjct: 299 KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRK 358

Query: 108 RKSFYSSHYARERSPYKRDNT--FFRESPVGRKDSPHSRSGSSVSSRSYSPERSK--SYS 163
           R    S   +R RS  +R       R+S  G              SRS S   SK   ++
Sbjct: 359 RSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHA 418

Query: 164 FHQSQHRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASK 216
             +S  R      ++  T+++T   S S   S   L   SR   K  ++  S+
Sbjct: 419 KSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSR 471



 Score = 32.0 bits (71), Expect = 0.84
 Identities = 48/225 (21%), Positives = 84/225 (37%), Gaps = 14/225 (6%)

Query: 62  DEGRSFSHDRRSGPPHRGDESGYRWTRDDHSA---SRQPEYRDMRDGFRRKSFYSSHYAR 118
           ++ RS SH          D++  +   +D+     SR P     +   R +S        
Sbjct: 253 EKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEE 312

Query: 119 ERSPYKRDNT---FFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERP 175
           +R    R  +     R+S    +    SRS S   S+S    + +  S  +S+ R++ R 
Sbjct: 313 KRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRS 372

Query: 176 VQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISE 235
                  R +   S +  S  K  +   R   +  + + SK   E+     ES+  E   
Sbjct: 373 KSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSK---EREHAKSESSQRE--- 426

Query: 236 YEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTK 280
              G +    T+Q     S +    +    S+  +RSK+ ASKT+
Sbjct: 427 -GRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKS-ASKTR 469



 Score = 30.0 bits (66), Expect = 3.2
 Identities = 41/160 (25%), Positives = 64/160 (40%), Gaps = 14/160 (8%)

Query: 47  GSYNRYYSHVDYRDYDEGRSFSHDR---RSGPPHRGDESGYRWTRDDHSASRQPEYRDMR 103
           GS +R  S    +D  +GR  S +    RS    + + S  R ++ D  A    + +   
Sbjct: 339 GSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKK-KKKE 397

Query: 104 DGFRRKSFYSSHYARERSPYKRDNTFFRESP-----VGRKDSPHSRSGSSVSSRSYSPE- 157
           D  R +S   S    +   + +  +  RE        G      SRS S+  S+   P  
Sbjct: 398 DTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSE 457

Query: 158 -RSKSYSFHQSQHRNKERPVQSLKTSRDTSPSSGSAVSSS 196
            RS+S S  +++ R+K R   S   SR  S S   + S S
Sbjct: 458 SRSRSKSASKTRSRSKSR---SRSASRSPSRSRSRSHSRS 494


>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
           sapiens]
          Length = 674

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 61/220 (27%), Positives = 81/220 (36%), Gaps = 26/220 (11%)

Query: 44  PGEGSYNRYYSHVDYRDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMR 103
           PG  +  R  S          R+ S    S    R    G  +    H+ SR   +   R
Sbjct: 367 PGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSR 426

Query: 104 DGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKD-SPHSRSGSSVSS----------- 151
              RR S   S   R      RD   +  SP  R    P  RS S   S           
Sbjct: 427 SRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGL 486

Query: 152 RSYSPERSKSYSFHQSQHRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDK---PSRLTEK 208
           R +S  RS+S S+  S  R++     SL  SR  SPS   + S S+   +   PS   EK
Sbjct: 487 RHHSSSRSRS-SWSLSPSRSR-----SLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREK 540

Query: 209 ELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQ 248
               AAS    EKL+K++ +     +  E G+  P  T Q
Sbjct: 541 LTRPAASPAVGEKLKKTEPA-----AGKETGAAKPKLTPQ 575


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 62/235 (26%), Positives = 78/235 (33%), Gaps = 43/235 (18%)

Query: 55  HVDYRDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSS 114
           H   R    GRS S  R   P  +  + G     D  S SR  + R  R   R K     
Sbjct: 7   HYRKRSASRGRSGSRSRSRSPSDKRSKRG----DDRRSRSRDRDRRRERSRSRDK----- 57

Query: 115 HYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKER 174
              R RS   RD    R S    +D    R  S    R  S  RS+      S   NK +
Sbjct: 58  --RRSRS---RDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSK 112

Query: 175 PVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKE-----------------LAEAASKW 217
             ++   SR    + G   S  K  DK  +  EKE                   E   KW
Sbjct: 113 KTEN--RSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKW 170

Query: 218 AAEKLEKSDES---NLPEISEYEAGSTAPLFTDQPE-------EPESNTTHGIEL 262
             E+ +K+ E+      EI E + G    L  D  +       E E N   G EL
Sbjct: 171 REEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEEL 225


>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
          Length = 1007

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 43/173 (24%), Positives = 70/173 (40%), Gaps = 7/173 (4%)

Query: 37  KPPLLDRPGEGSYNRYYSHVDYRDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQ 96
           K P L R  +    +  S  D +   E +S S DR+  P      S  R  +       +
Sbjct: 240 KSPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLR 299

Query: 97  PEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKD-SPHSRSGSSVSSRSYS 155
            + +D R   + +    S   +E+ P K  +   +++  G+++ SP  R G S   RS S
Sbjct: 300 GKSKDRRSRSKERKSKRSETDKEKKPIKSPS---KDASSGKENRSPSRRPGRSPKRRSLS 356

Query: 156 PERSKSYSFHQSQHRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEK 208
           P+        +S   N  R  QS   SR  SP      + S+ L++  R  E+
Sbjct: 357 PKPRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRR---AKSRSLERKRREPER 406



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 73/304 (24%), Positives = 111/304 (36%), Gaps = 35/304 (11%)

Query: 14  RERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRDYDEGRS-FSHDRR 72
           +E+ P +S   D  +   N  P +     RPG     R  S          RS   +DRR
Sbjct: 321 KEKKPIKSPSKDASSGKENRSPSR-----RPGRSPKRRSLSPKPRDKSRRSRSPLLNDRR 375

Query: 73  SGP---PHRGDESGYRW-TRDDHSASRQPEYRDM---RDGFRRKSFYSSHYARERSPYKR 125
           S     P R    G R  +R      R+PE R +   R   R         +++ SP  R
Sbjct: 376 SKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLSSPRTRPRDDILSRRERSKDASPINR 435

Query: 126 DNTFFRES--PVGRKDSPHSRSGSSVSSRSYSP------ERSKSYSFHQSQHRNKERPVQ 177
            +   R S  P+ R+     R   S   RS SP       RS+S    +S+ R   R   
Sbjct: 436 WSPTRRRSRSPIRRRSRSPLRRSRSPRRRSRSPRRRDRGRRSRSRLRRRSRSRGGRRRRS 495

Query: 178 SLKTSRDT---SPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEIS 234
             K   D    S S G  V      D    L + ++ E   +   E+  +     + +  
Sbjct: 496 RSKVKEDKFKGSLSEGMKVEQESSSD--DNLEDFDVEEEDEEALIEQ-RRIQRQAIVQKY 552

Query: 235 EYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQDCETFG 294
           +Y A  +      +P  P+S+T       +D       + +A+  KE E   R++ +TF 
Sbjct: 553 KYLAEDSNMSVPSEPSSPQSSTRTRSPSPDDI-----LERVAADVKEYE---RENVDTFE 604

Query: 295 MVVK 298
             VK
Sbjct: 605 ASVK 608


>gi|38016935 MLF1 interacting protein [Homo sapiens]
          Length = 418

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 58/278 (20%), Positives = 102/278 (36%), Gaps = 46/278 (16%)

Query: 13  PRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRDYDEGRSFSHDRR 72
           PR R  PR H S+G  R  N + +   + D+ G+         +D  D+ +    S   R
Sbjct: 3   PRGRRRPRPHRSEGARRSKNTLERTHSMKDKAGQKC-----KPIDVFDFPDNSDVSSIGR 57

Query: 73  SGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRE 132
            G   + +E+   +    HS +    Y D  +       +S H     S         R 
Sbjct: 58  LGENEKDEETYETFDPPLHSTA---IYADEEE-------FSKHCGLSLSSTPPGKEAKRS 107

Query: 133 SPVGRKDSPHSRS---GSSVSSRSYSPERSKSYSFHQSQHRNKERPVQSLKTSRDTSPSS 189
           S     ++    S    +    R   P    S S  +S  R K +  + + T R     +
Sbjct: 108 SDTSGNEASEIESVKISAKKPGRKLRPISDDSESIEESDTRRKVKSAEKISTQRHEVIRT 167

Query: 190 GSAVSSSKVLDKPSR-LTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQ 248
               +SS++ +KP+  +T K+    +++ + EK   + ES                    
Sbjct: 168 ---TASSELSEKPAESVTSKKTGPLSAQPSVEKENLAIES-------------------- 204

Query: 249 PEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVY 286
               +S T    ++  D +  +RSKAI S T +I  ++
Sbjct: 205 ----QSKTQKKGKISHDKRKKSRSKAIGSDTSDIVHIW 238


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 61/225 (27%), Positives = 89/225 (39%), Gaps = 39/225 (17%)

Query: 10  ERIPR----ERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRDYDEGR 65
           E++P+    E +PP   P+   +R  +  P+ P     P  GS+    S    ++   GR
Sbjct: 410 EKLPQSSSSESSPPSPQPTK-VSRHASSSPESPK--PAPAPGSHREISSSPTSKNRSHGR 466

Query: 66  -----SFSH--DRRSGPPH------RGDESGYRWTRDDHSASRQPEYRDMRDGFR-RKSF 111
                S SH   RR G         RG       T+  HS SR P++R  R   R  +S 
Sbjct: 467 AKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSR 526

Query: 112 YSSHYARERSPYK------RDNTFFRESPVGRKDSPHSRS----GSSVS--------SRS 153
                 R RSP +      R+      S   R+   HSRS    G S S        SRS
Sbjct: 527 SPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRS 586

Query: 154 YSPERSKSYSFHQSQHRNKERPVQSLKTSRDTSPSSGSAVSSSKV 198
            +P R +S S   ++ R++ R       SR  +P+   + + S V
Sbjct: 587 RTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPV 631



 Score = 33.1 bits (74), Expect = 0.38
 Identities = 57/220 (25%), Positives = 80/220 (36%), Gaps = 38/220 (17%)

Query: 14   RERAPPRSHP-SDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRDYDEGRSFSHDRR 72
            + RA PR+   SD         P+  P   R G  S  R  S        EG S +    
Sbjct: 1607 KPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPS-------PEGSSSTESSP 1659

Query: 73   SGPPH-RGDESGYRWTRDDHSASRQPEYR-----------DMRDGFRRKSFYSSHYARER 120
              PP  R    G R + +  + SR P  R             R   R +S  SS   R R
Sbjct: 1660 EHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSR 1719

Query: 121  SPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYS------------FHQSQ 168
            +P +      R SP      P  +S SS   RS S  R+K+ S              +S+
Sbjct: 1720 TPPRH-----RRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSR 1774

Query: 169  HRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEK 208
             R++    ++ +  RD S SS S     +     SR+T +
Sbjct: 1775 SRSRREKTRTTR-RRDRSGSSQSTSRRRQRSRSRSRVTRR 1813



 Score = 32.0 bits (71), Expect = 0.84
 Identities = 32/127 (25%), Positives = 55/127 (43%), Gaps = 7/127 (5%)

Query: 155  SPERSKSYSFHQSQHRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAA 214
            SP+     S  + +  + E P  SL++   TSP  G + SSS V +  SR     + +  
Sbjct: 1064 SPDHRSDTSSPEVRQSHSESP--SLQSKSQTSPKGGRSRSSSPVTELASR---SPIRQDR 1118

Query: 215  SKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKA 274
             +++A  + KS  S  PE S +++ S++    D       +     E  E   L  +  A
Sbjct: 1119 GEFSASPMLKSGMS--PEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDA 1176

Query: 275  IASKTKE 281
             AS  ++
Sbjct: 1177 TASPPRQ 1183



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 41/170 (24%), Positives = 60/170 (35%), Gaps = 13/170 (7%)

Query: 72   RSGPPHRGDESGYRWTRDDHSASR--QPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTF 129
            ++ P HR D S     R  HS S   Q + +    G R +S         RSP ++D   
Sbjct: 1062 QTSPDHRSDTSSPE-VRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGE 1120

Query: 130  FRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERPVQSLKTSRDTS--- 186
            F  SP+ +      +S     S SY    S S          + +   +L    D +   
Sbjct: 1121 FSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASP 1180

Query: 187  PSSGSAVSSSKVLDKP-SRLTEKELAEAASKWAAEKLEKSDESNLPEISE 235
            P      S   V D+P S L  K+      +      E+S   + PE  E
Sbjct: 1181 PRQKDKFSPFPVQDRPESSLVFKDTLRTPPR------ERSGAGSSPETKE 1224



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 7/105 (6%)

Query: 117  ARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSF---HQSQHRNKE 173
            A  R+    D++   ++P  R     SRSGSS   R  SPE S S      H  + R   
Sbjct: 1610 AAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTAR 1669

Query: 174  RPVQSL---KTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAAS 215
            R  +S    KT   T P   S+ SS + L + +RL+ +  + ++S
Sbjct: 1670 RGSRSSPEPKTKSRTPPRRRSSRSSPE-LTRKARLSRRSRSASSS 1713



 Score = 30.0 bits (66), Expect = 3.2
 Identities = 73/299 (24%), Positives = 95/299 (31%), Gaps = 70/299 (23%)

Query: 3   SEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEG------SYNRYYSHV 56
           S  R+   R P+ R   RS    G++R  N   +      R G        +  R  S  
Sbjct: 518 SAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRT 577

Query: 57  DYRDYDEGRSFSHD-----RRSGPPHRGDESGYRWTRDDHSASRQPEYRDMR--DGFRRK 109
             R    GRS S        RS  P R         R   S SR P  R  R     RR+
Sbjct: 578 PAR---RGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRR 634

Query: 110 SFYSSHYARERSPYKRDNTFFRESPV---------------GRKDSPHSRSGSSVS---- 150
           S       R RSP +R       +P                 R  +P  RSG S S    
Sbjct: 635 S-------RSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPA 687

Query: 151 ----SRSYSPERSKS--------------------YSFHQSQHRNKERPVQSLKTSRDTS 186
               SRS +P R +S                     S   S+ +NK R  Q    S  + 
Sbjct: 688 RRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSP 747

Query: 187 PSSGSAVSS--SKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAP 243
               S +SS  S+ L  P    +  L+   S   +    K      P  S   +GS+ P
Sbjct: 748 EMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRS--RSGSSQP 804



 Score = 29.3 bits (64), Expect = 5.5
 Identities = 49/243 (20%), Positives = 85/243 (34%), Gaps = 31/243 (12%)

Query: 63  EGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSP 122
           E  S     RS  P    +S  +  +   S +  P+ R         S  SS  +R RS 
Sbjct: 221 ESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSR 280

Query: 123 YKRDNTFFRE------SPV----GRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNK 172
                T          SP     G  D+P S  G++ + R  SPE +        + ++K
Sbjct: 281 SAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDK 340

Query: 173 ERPVQSL--------KTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEK 224
           ++  +S         ++S    P + + + + +    P  L    L++      +E    
Sbjct: 341 DKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPT 400

Query: 225 SDES------NLPEISEYEAGSTAPLFT-------DQPEEPESNTTHGIELFEDSQLTTR 271
            D S       LP+ S  E+   +P  T         PE P+     G      S  T++
Sbjct: 401 RDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSK 460

Query: 272 SKA 274
           +++
Sbjct: 461 NRS 463



 Score = 29.3 bits (64), Expect = 5.5
 Identities = 32/122 (26%), Positives = 46/122 (37%), Gaps = 14/122 (11%)

Query: 133  SPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERPVQSLKTSRDTSPSSGSA 192
            +P  RK    S S SS SS S S   S S S              S  +S  +S SS S+
Sbjct: 2599 TPAKRKRRSSSSSSSSSSSSSSSSSSSSSSS--------------SSSSSSSSSSSSSSS 2644

Query: 193  VSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEP 252
             SSS    KP      + A        E+  +S    +  + +  + S +P+   +P   
Sbjct: 2645 SSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQ 2704

Query: 253  ES 254
             S
Sbjct: 2705 PS 2706



 Score = 28.5 bits (62), Expect = 9.3
 Identities = 42/197 (21%), Positives = 71/197 (36%), Gaps = 4/197 (2%)

Query: 65   RSFSHDRRSGPPHRGDESGY--RWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSP 122
            RS S  R      RG       R  +   S SR+ + R  R   R  S  S+   R+RS 
Sbjct: 1746 RSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSR 1805

Query: 123  YKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERPVQSLKTS 182
             +   T  R    G      +R  SS +S      RS++    + + R++  P    ++ 
Sbjct: 1806 SRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSR 1865

Query: 183  RDTSPSS--GSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGS 240
               SP++   S   +  +  + SR     ++   S+       +   S    +S   + S
Sbjct: 1866 SRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRS 1925

Query: 241  TAPLFTDQPEEPESNTT 257
              P  T +     + TT
Sbjct: 1926 RTPPVTRRRSRSRTPTT 1942


>gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]
          Length = 221

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 43/129 (33%), Positives = 55/129 (42%), Gaps = 6/129 (4%)

Query: 68  SHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDN 127
           SH  R GPP R    G  + R   S  R+   R  R   R +S   S Y+R +S   R  
Sbjct: 98  SHHSRRGPPPR-RYGGGGYGRRSRSPRRRRRSRS-RSRSRSRSRSRSRYSRSKS---RSR 152

Query: 128 TFFRESPVGR-KDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERPVQSLKTSRDTS 186
           T  R     + + +  S+S SS  SRS S  RS+S S        +E   +S   S   S
Sbjct: 153 TRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKS 212

Query: 187 PSSGSAVSS 195
           P    AVSS
Sbjct: 213 PEEEGAVSS 221



 Score = 35.0 bits (79), Expect = 0.100
 Identities = 38/132 (28%), Positives = 59/132 (44%), Gaps = 12/132 (9%)

Query: 114 SHYARERSPYKRDNTFFRESPVGRKD-SPHSRSGSSVSSRSYSPERSKS-YSFHQSQHRN 171
           SH++R   P +R    +     GR+  SP  R  S   SRS S  RS+S YS  +S+ R 
Sbjct: 98  SHHSRRGPPPRR----YGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRT 153

Query: 172 KERPVQSLKT-SRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNL 230
           + R   + K+ S   S S  S+VS S+     SR   +  + +    +  + +    S  
Sbjct: 154 RSRSRSTSKSRSARRSKSKSSSVSRSR-----SRSRSRSRSRSPPPVSKRESKSRSRSKS 208

Query: 231 PEISEYEAGSTA 242
           P  S  E G+ +
Sbjct: 209 PPKSPEEEGAVS 220



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 43/145 (29%), Positives = 50/145 (34%), Gaps = 32/145 (22%)

Query: 69  HDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNT 128
           H RR  PP R    GY         SR P  R       R    S   +R RS Y R   
Sbjct: 100 HSRRGPPPRRYGGGGYG------RRSRSPRRRRRS----RSRSRSRSRSRSRSRYSRSK- 148

Query: 129 FFRESPVGRKDSPHSRSGSSVSSR----SYSPERSKSYSFHQSQHRNKERPVQSLKTSRD 184
                         SRS +   SR    S S  RSKS S   S+ R++ R   S   SR 
Sbjct: 149 --------------SRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSR---SRSRSRS 191

Query: 185 TSPSSGSAVSSSKVLDKPSRLTEKE 209
             P S     S      P +  E+E
Sbjct: 192 PPPVSKRESKSRSRSKSPPKSPEEE 216


>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
          Length = 484

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 54/222 (24%), Positives = 79/222 (35%), Gaps = 28/222 (12%)

Query: 59  RDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYAR 118
           R +   RS S  RR+    R   S  R  R  HS SR    R  +   RR+S       R
Sbjct: 246 RRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSR--RRSKSPRRRRSHSRERGRR 303

Query: 119 ERSPYKRDNTFFRESPVGRKDSP--------------------HSRSGSSVSSRSYSPER 158
            RS  K  +    +    R  +P                     SRSG+    +  SP+R
Sbjct: 304 SRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKR 363

Query: 159 SKSYSFHQSQHRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWA 218
             S S    +H+ +++  +  + SRD    S S    SK  +K     ++E    + K  
Sbjct: 364 KLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEK-----DRERKSESDKDV 418

Query: 219 AEKLEKSDESNLPEISEYE-AGSTAPLFTDQPEEPESNTTHG 259
            +     DE      SE E      P+ T  P+  E +   G
Sbjct: 419 KQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKG 460


>gi|34996489 pleckstrin homology domain interacting protein [Homo
            sapiens]
          Length = 1821

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 33/132 (25%), Positives = 60/132 (45%), Gaps = 7/132 (5%)

Query: 107  RRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQ 166
            R  +F+  H +   S YK    F + + + ++    +RS S  SS + SPER K     Q
Sbjct: 1409 RLSAFFEEHISSVLSDYKSALRFHKRNTITKRRKKRNRSSSVSSSAASSPERKKRILKPQ 1468

Query: 167  SQHRNK----ERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSR-LTEKELAEAASKWAAEK 221
             +  +       P +S+    + +  +G   SSS V  + +R + +  + E  S  +A K
Sbjct: 1469 LKSESSTSAFSTPTRSIPPRHNAAQINGKTESSSVVRTRSNRVVVDPVVTEQPSTSSAAK 1528

Query: 222  --LEKSDESNLP 231
              + K++ S +P
Sbjct: 1529 TFITKANASAIP 1540


>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
          Length = 3664

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 52/196 (26%), Positives = 78/196 (39%), Gaps = 34/196 (17%)

Query: 45  GEGSYNR--YYSHVDYRDYDEGRSFSHD----RRSGPPHRGDESGYRWTRDDHSASRQPE 98
           G G ++R  +Y    YRD  E R+  H      RS  P+R D    R+          P 
Sbjct: 155 GTGGFDRTRHYDQDYYRDPRE-RTLQHGLYYASRSRSPNRFDAHDPRYEPRAREQFTLPS 213

Query: 99  ------YRD--MRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVS 150
                 YRD   R+   R+   +  ++R RSP+         S   R  SP       ++
Sbjct: 214 VVHRDIYRDDITREVRGRRPERNYQHSRSRSPH---------SSQSRNQSPQR-----LA 259

Query: 151 SRSYSPERSKSYSFHQSQHRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKEL 210
           S++  P RS S S  +S+  + +    S  TS D+S SS S+       D P+R  +   
Sbjct: 260 SQASRPTRSPSGSGSRSRSSSSDSISSSSSTSSDSSDSSSSSSD-----DSPARSVQSAA 314

Query: 211 AEAASKWAAEKLEKSD 226
             A +      LEK +
Sbjct: 315 VPAPTSQLLSSLEKDE 330



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 60/240 (25%), Positives = 88/240 (36%), Gaps = 33/240 (13%)

Query: 38  PPLLDRPGEGSYNRYYSHVDYRDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQP 97
           PP      EG Y R    +D    +  R++ H    G   RG     R    D    R P
Sbjct: 118 PPPSLHAREGRYER---RLDGASDNRERAYEHSAY-GHHERGTGGFDRTRHYDQDYYRDP 173

Query: 98  EYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHS--------RSGSSV 149
             R ++ G     +Y+S   R RSP + D    R  P  R+             R   + 
Sbjct: 174 RERTLQHGL----YYAS---RSRSPNRFDAHDPRYEPRAREQFTLPSVVHRDIYRDDITR 226

Query: 150 SSRSYSPER----SKSYSFHQSQHRNKERPVQSLKTSRDTSPSSGS---AVSSSKVLDKP 202
             R   PER    S+S S H SQ RN+     + + SR T   SGS   + SSS      
Sbjct: 227 EVRGRRPERNYQHSRSRSPHSSQSRNQSPQRLASQASRPTRSPSGSGSRSRSSSSDSISS 286

Query: 203 SRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIEL 262
           S  T  + ++++S         SD+S    +      +         E+ E   + GI++
Sbjct: 287 SSSTSSDSSDSSS-------SSSDDSPARSVQSAAVPAPTSQLLSSLEKDEPRKSFGIKV 339


>gi|50083281 KIAA1853 protein [Homo sapiens]
          Length = 611

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 41/137 (29%), Positives = 53/137 (38%), Gaps = 16/137 (11%)

Query: 82  SGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSP 141
           S Y  TR    +SR P  R      + +S  S   +  RSP     +  R  P     S 
Sbjct: 393 SSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPP-----SR 447

Query: 142 HSRSGSSVSSRSYSP--ERSKSYSFHQSQHRNKERPVQSLKTSRDTSPSSGSAVSSSKVL 199
            SRS  S S   YSP  ER   YS   SQ R +ER   + +  R  SP         +  
Sbjct: 448 SSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERER---ARRRRRSYSP------MRKRRR 498

Query: 200 DKPSRLTEKELAEAASK 216
           D PS L  + +  A  +
Sbjct: 499 DSPSHLEARRITSARKR 515



 Score = 35.4 bits (80), Expect = 0.076
 Identities = 53/184 (28%), Positives = 68/184 (36%), Gaps = 42/184 (22%)

Query: 65  RSFSHDRRSG---PPHRGDES--GYRWTRDDHSASRQPEY-------RDMRDGFRRKSFY 112
           RS S+  +SG   PP R   S     ++R   S  R P+Y       R+     RR+  Y
Sbjct: 431 RSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSY 490

Query: 113 SSHYARER------------SPYKRDNTFFRESPVGRKD---------SPHSRSGSSVSS 151
           S    R R            S  KR   ++R SP              S  SRS S    
Sbjct: 491 SPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASR--- 547

Query: 152 RSYSPERSKSYSFHQSQHRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELA 211
            SYS  RS+S S  +S+ R       S  +SR  SP S S   S       SR   +  +
Sbjct: 548 -SYSRSRSRSRSRRRSRTR-----TSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYS 601

Query: 212 EAAS 215
            A S
Sbjct: 602 SADS 605



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 54/205 (26%), Positives = 72/205 (35%), Gaps = 41/205 (20%)

Query: 11  RIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGS-------------YNRY----- 52
           R P  RA PR   S   +       + P    + G+ S             Y+RY     
Sbjct: 406 RSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRE 465

Query: 53  ----YSHVDYRDYDEGRSFSHDRRSGP--PHRGDESGYRWTRDDHSASRQP--EYRDMRD 104
               YS  D +  +  R+    R   P    R D   +   R   SA ++P   YR    
Sbjct: 466 RDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPS 525

Query: 105 GF----RRKSFYSSH--------YARERS---PYKRDNTFFRESPVGRKDSPHSRSGSSV 149
                    S+YSS         Y+R RS     +R  T    S   R  SP SRS S  
Sbjct: 526 SSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRS 585

Query: 150 SSRSYSPERSKSYSFHQSQHRNKER 174
            SRS S  RS+S S+  +   +  R
Sbjct: 586 RSRSRSRSRSQSRSYSSADSYSSTR 610



 Score = 32.0 bits (71), Expect = 0.84
 Identities = 29/126 (23%), Positives = 47/126 (37%), Gaps = 15/126 (11%)

Query: 64  GRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPY 123
           G S SHD+   PP               S  ++ + +  R   RR S YS    +++   
Sbjct: 91  GHSASHDKDLTPP-------------PSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKK-- 135

Query: 124 KRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERPVQSLKTSR 183
           K+ +   +      K   HS S      R     + +S S  +  HR++     S   S 
Sbjct: 136 KKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSS 195

Query: 184 DTSPSS 189
           ++ PSS
Sbjct: 196 ESRPSS 201


>gi|24762236 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing A [Homo sapiens]
          Length = 312

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 37/111 (33%), Positives = 50/111 (45%), Gaps = 8/111 (7%)

Query: 80  DESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKD 139
           DE   R    DH   R+  YRD+ D  RR        +R RSP +R  +  R SP  R++
Sbjct: 201 DEKLERVPSPDH---RRRSYRDL-DKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRE 256

Query: 140 SPHSRSGSSVSSRSYS---PERSKSYSFHQS-QHRNKERPVQSLKTSRDTS 186
              S+S     SRS       RSKS   H+S +HR+  +  +  K S   S
Sbjct: 257 RHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKS 307


>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
          Length = 344

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 41/151 (27%), Positives = 57/151 (37%), Gaps = 10/151 (6%)

Query: 76  PHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYK---RDNTFFRE 132
           P       Y  +R    + R+   R  R    R    S   +R RS  K   R  +  R+
Sbjct: 183 PRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRK 242

Query: 133 SPVGRKDSPHSRSGSSVSSRSYSP---ERSKSYSFHQSQHRNKERPVQSLKTS----RDT 185
           S    K  P S  GS   SRS S    E+S+S S  +S   N +  ++S   S    R  
Sbjct: 243 SRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSN 302

Query: 186 SPSSGSAVSSSKVLDKPSRLTEKELAEAASK 216
           SP       +  V   P R T +  + + SK
Sbjct: 303 SPLPVPPSKARSVSPPPKRATSRSRSRSRSK 333



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 3/127 (2%)

Query: 118 RERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERPVQ 177
           + R+ ++R  +  R     R+    SRS S  SSRS S   SKS S  +S+ + + R   
Sbjct: 182 KPRTSHRRSYSGSRSRSRSRR---RSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRS 238

Query: 178 SLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYE 237
             + SR  S S   +   S    +     E E + + S+  + K     +      S  +
Sbjct: 239 KGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQ 298

Query: 238 AGSTAPL 244
           + S +PL
Sbjct: 299 SRSNSPL 305



 Score = 28.9 bits (63), Expect = 7.1
 Identities = 39/149 (26%), Positives = 56/149 (37%), Gaps = 20/149 (13%)

Query: 43  RPGEGSYNRYYSHVDYRDYDEGRSFSHDRRSGPPHRG-DESGYRWTRDDHSASRQPEYRD 101
           R    S +R  S    R     +  S  R  G   R   +S  +  R  HS SR      
Sbjct: 209 RRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRS----- 263

Query: 102 MRDGFRRKSFYSSHYARERSPYKRDN------TFFRESPVGRKDSPHSRSGSSVSSRSYS 155
                R K  Y    +R RS   ++N      +  R     R +SP     S   S S  
Sbjct: 264 -----RSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPP 318

Query: 156 PERSKSYSFHQSQHRNKERPVQSLKTSRD 184
           P+R+ S S  +S+ +++ R   S  +SRD
Sbjct: 319 PKRATSRSRSRSRSKSRSR---SRSSSRD 344


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 49/164 (29%), Positives = 65/164 (39%), Gaps = 18/164 (10%)

Query: 59   RDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYAR 118
            R+    RS S D R     R      R     H+ SR+   R  R   RR+SF  S   R
Sbjct: 1902 RERKRKRSSSRDNRKTVRARSRTPSRR--SRSHTPSRR---RRSRSVGRRRSFSISPSRR 1956

Query: 119  ERSPYKRDNTFFRES--PVGRKDSPHSRSGS--------SVSSRSYSPERSKSYSFHQSQ 168
             R+P +R  T  R S  P  R  +P  RS +        S   RS S  R +S+S    +
Sbjct: 1957 SRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVR 2016

Query: 169  HRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAE 212
             R    P   L+     SP       SS+    P RLT+ + A+
Sbjct: 2017 LRRSRTP---LRRRFSRSPIRRKRSRSSERGRSPKRLTDLDKAQ 2057



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 54/180 (30%), Positives = 68/180 (37%), Gaps = 17/180 (9%)

Query: 65   RSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDM-RDGFRRKSFYSS--HYARERS 121
            RS +  RRS  P R   +  R +R     SR P  R   R   RR+SF  S     R R+
Sbjct: 1963 RSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRT 2022

Query: 122  PYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNK-ERPVQSLK 180
            P +R    F  SP+ RK    SRS    S R  SP+R       Q     K        K
Sbjct: 2023 PLRRR---FSRSPIRRK---RSRS----SERGRSPKRLTDLDKAQLLEIAKANAAAMCAK 2072

Query: 181  TSRDTSPSSGSA---VSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYE 237
                  P+   A       KV  K    T +EL E   + A  K +     N P +S+ E
Sbjct: 2073 AGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEKCKQIAQSKEDDDVIVNKPHVSDEE 2132



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 35/120 (29%), Positives = 49/120 (40%), Gaps = 4/120 (3%)

Query: 88   RDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYK---RDNTFFRESPVGRKDSPHSR 144
            RD    SR    +      R+++  S   AR+RS      R  T  R     R+ S  SR
Sbjct: 1818 RDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSR 1877

Query: 145  SGSSVSSRSYSPERSKSYSFHQSQHRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSR 204
            S S    RS S E+ K    H+S+ R ++R   S + +R T  +     S       PSR
Sbjct: 1878 SKSR-GRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSR 1936



 Score = 36.2 bits (82), Expect = 0.045
 Identities = 42/161 (26%), Positives = 69/161 (42%), Gaps = 12/161 (7%)

Query: 60   DYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARE 119
            D    RS +    S  P R  ES     +DD+       +  ++D    KS  + +  + 
Sbjct: 1760 DVGRDRSAASPVVSSMPERASESSSE-EKDDYEI-----FVKVKDT-HEKSKKNKNRDKG 1812

Query: 120  RSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERPVQSL 179
                KRD++  R      K S H     +  SRS + +RS     H+SQ R++ R  +  
Sbjct: 1813 EKEKKRDSSL-RSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRR 1871

Query: 180  KTSRDTSPSSG-SAVSSSKVLDKP---SRLTEKELAEAASK 216
            ++SR  S S G  +VS  K    P   S+  E++   ++S+
Sbjct: 1872 RSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSR 1912


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 38.5 bits (88), Expect = 0.009
 Identities = 49/164 (29%), Positives = 65/164 (39%), Gaps = 18/164 (10%)

Query: 59   RDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYAR 118
            R+    RS S D R     R      R     H+ SR+   R  R   RR+SF  S   R
Sbjct: 1902 RERKRKRSSSRDNRKTVRARSRTPSRR--SRSHTPSRR---RRSRSVGRRRSFSISPSRR 1956

Query: 119  ERSPYKRDNTFFRES--PVGRKDSPHSRSGS--------SVSSRSYSPERSKSYSFHQSQ 168
             R+P +R  T  R S  P  R  +P  RS +        S   RS S  R +S+S    +
Sbjct: 1957 SRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVR 2016

Query: 169  HRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAE 212
             R    P   L+     SP       SS+    P RLT+ + A+
Sbjct: 2017 LRRSRTP---LRRRFSRSPIRRKRSRSSERGRSPKRLTDLDKAQ 2057



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 54/180 (30%), Positives = 68/180 (37%), Gaps = 17/180 (9%)

Query: 65   RSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDM-RDGFRRKSFYSS--HYARERS 121
            RS +  RRS  P R   +  R +R     SR P  R   R   RR+SF  S     R R+
Sbjct: 1963 RSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRT 2022

Query: 122  PYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNK-ERPVQSLK 180
            P +R    F  SP+ RK    SRS    S R  SP+R       Q     K        K
Sbjct: 2023 PLRRR---FSRSPIRRK---RSRS----SERGRSPKRLTDLDKAQLLEIAKANAAAMCAK 2072

Query: 181  TSRDTSPSSGSA---VSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYE 237
                  P+   A       KV  K    T +EL E   + A  K +     N P +S+ E
Sbjct: 2073 AGVPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEKCKQIAQSKEDDDVIVNKPHVSDEE 2132



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 35/120 (29%), Positives = 49/120 (40%), Gaps = 4/120 (3%)

Query: 88   RDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYK---RDNTFFRESPVGRKDSPHSR 144
            RD    SR    +      R+++  S   AR+RS      R  T  R     R+ S  SR
Sbjct: 1818 RDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSR 1877

Query: 145  SGSSVSSRSYSPERSKSYSFHQSQHRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSR 204
            S S    RS S E+ K    H+S+ R ++R   S + +R T  +     S       PSR
Sbjct: 1878 SKSR-GRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSR 1936



 Score = 36.2 bits (82), Expect = 0.045
 Identities = 42/161 (26%), Positives = 69/161 (42%), Gaps = 12/161 (7%)

Query: 60   DYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARE 119
            D    RS +    S  P R  ES     +DD+       +  ++D    KS  + +  + 
Sbjct: 1760 DVGRDRSAASPVVSSMPERASESSSE-EKDDYEI-----FVKVKDT-HEKSKKNKNRDKG 1812

Query: 120  RSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRNKERPVQSL 179
                KRD++  R      K S H     +  SRS + +RS     H+SQ R++ R  +  
Sbjct: 1813 EKEKKRDSSL-RSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRR 1871

Query: 180  KTSRDTSPSSG-SAVSSSKVLDKP---SRLTEKELAEAASK 216
            ++SR  S S G  +VS  K    P   S+  E++   ++S+
Sbjct: 1872 RSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSR 1912


>gi|38488727 arginine/serine-rich coiled-coil 1 [Homo sapiens]
          Length = 334

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 53/215 (24%), Positives = 81/215 (37%), Gaps = 6/215 (2%)

Query: 88  RDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGS 147
           R   S+S        + G R+    S  ++R+  P  R +++ R     R  S  S    
Sbjct: 23  RSSSSSSSDSRTYSRKKGGRKSRSKSRSWSRDLQP--RSHSYDRRRR-HRSSSSSSYGSR 79

Query: 148 SVSSRSYSPERSKSYSFHQSQHRNKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTE 207
              SRS S  R KSY   +S  R+K R  +S    R  S S  S  SS +     SR  E
Sbjct: 80  RKRSRSRSRGRGKSYRVQRS--RSKSRTRRSRSRPRLRSHSRSSERSSHRRTRSRSRDRE 137

Query: 208 KELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQ 267
           +       K   EK +K  +  L  I   E+G+        P   ++     + L   ++
Sbjct: 138 RRKGRDKEKREKEK-DKGKDKELHNIKRGESGNIKAGLEHLPPAEQAKARLQLVLEAAAK 196

Query: 268 LTTRSKAIASKTKEIEQVYRQDCETFGMVVKMLIE 302
                KA     +E ++   +D  T    VK + E
Sbjct: 197 ADEALKAKERNEEEAKRRKEEDQATLVEQVKRVKE 231


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.128    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,063,955
Number of Sequences: 37866
Number of extensions: 739477
Number of successful extensions: 3310
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 85
Number of HSP's successfully gapped in prelim test: 233
Number of HSP's that attempted gapping in prelim test: 2535
Number of HSP's gapped (non-prelim): 708
length of query: 348
length of database: 18,247,518
effective HSP length: 103
effective length of query: 245
effective length of database: 14,347,320
effective search space: 3515093400
effective search space used: 3515093400
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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