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Search of human proteins with 219275578
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|219275578 SIX homeobox 2 [Homo sapiens]
(291 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|219275578 SIX homeobox 2 [Homo sapiens] 607 e-174
gi|5174681 SIX homeobox 1 [Homo sapiens] 435 e-122
gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens] 289 2e-78
gi|186910311 SIX homeobox 6 [Homo sapiens] 285 3e-77
gi|142976638 sine oculis homeobox homolog 4 [Homo sapiens] 261 4e-70
gi|40354216 sine oculis homeobox homolog 5 [Homo sapiens] 230 1e-60
gi|15149472 pre-B-cell leukemia homeobox 4 [Homo sapiens] 60 2e-09
gi|46249382 paired-like homeobox 2a [Homo sapiens] 57 1e-08
gi|27436887 pre-B-cell leukemia homeobox 2 [Homo sapiens] 55 9e-08
gi|4505623 pre-B-cell leukemia homeobox 1 [Homo sapiens] 54 1e-07
gi|198041755 pre-B-cell leukemia homeobox 3 isoform 2 [Homo sapi... 53 3e-07
gi|5453852 pre-B-cell leukemia homeobox 3 isoform 1 [Homo sapiens] 53 3e-07
gi|34328941 TGFB-induced factor homeobox 2-like, X-linked [Homo ... 52 6e-07
gi|24762250 Meis homeobox 2 isoform d [Homo sapiens] 52 6e-07
gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens] 51 1e-06
gi|4505151 Meis homeobox 1 [Homo sapiens] 51 1e-06
gi|57863281 Meis1, myeloid ecotropic viral integration site 1 ho... 51 1e-06
gi|57863279 Meis1, myeloid ecotropic viral integration site 1 ho... 50 2e-06
gi|27502383 Meis homeobox 2 isoform h [Homo sapiens] 50 2e-06
gi|27502381 Meis homeobox 2 isoform g [Homo sapiens] 50 2e-06
gi|24762244 Meis homeobox 2 isoform a [Homo sapiens] 50 2e-06
gi|24762241 Meis homeobox 2 isoform c [Homo sapiens] 50 2e-06
gi|24762246 Meis homeobox 2 isoform b [Homo sapiens] 50 2e-06
gi|24762225 Meis homeobox 2 isoform f [Homo sapiens] 50 2e-06
gi|139394646 iroquois homeobox protein 5 [Homo sapiens] 50 2e-06
gi|7110735 ventral anterior homeobox 2 [Homo sapiens] 49 7e-06
gi|239751129 PREDICTED: hypothetical protein XP_002347726 [Homo ... 48 9e-06
gi|239745620 PREDICTED: hypothetical protein XP_002344158 [Homo ... 48 9e-06
gi|28178843 TG-interacting factor isoform a [Homo sapiens] 47 2e-05
gi|4507473 TG-interacting factor isoform c [Homo sapiens] 47 2e-05
>gi|219275578 SIX homeobox 2 [Homo sapiens]
Length = 291
Score = 607 bits (1565), Expect = e-174
Identities = 291/291 (100%), Positives = 291/291 (100%)
Query: 1 MSMLPTFGFTQEQVACVCEVLQQGGNIERLGRFLWSLPACEHLHKNESVLKAKAVVAFHR 60
MSMLPTFGFTQEQVACVCEVLQQGGNIERLGRFLWSLPACEHLHKNESVLKAKAVVAFHR
Sbjct: 1 MSMLPTFGFTQEQVACVCEVLQQGGNIERLGRFLWSLPACEHLHKNESVLKAKAVVAFHR 60
Query: 61 GNFRELYKILESHQFSPHNHAKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRS 120
GNFRELYKILESHQFSPHNHAKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRS
Sbjct: 61 GNFRELYKILESHQFSPHNHAKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRS 120
Query: 121 IWDGEETSYCFKEKSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDR 180
IWDGEETSYCFKEKSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDR
Sbjct: 121 IWDGEETSYCFKEKSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDR 180
Query: 181 AAEAKERENNENSNSNSHNPLNGSGKSVLGSSEDEKTPSGTPDHSSSSPALLLSPPPPGL 240
AAEAKERENNENSNSNSHNPLNGSGKSVLGSSEDEKTPSGTPDHSSSSPALLLSPPPPGL
Sbjct: 181 AAEAKERENNENSNSNSHNPLNGSGKSVLGSSEDEKTPSGTPDHSSSSPALLLSPPPPGL 240
Query: 241 PSLHSLGHPPGPSAVPVPVPGGGGADPLQHHHGLQDSILNPMSANLVDLGS 291
PSLHSLGHPPGPSAVPVPVPGGGGADPLQHHHGLQDSILNPMSANLVDLGS
Sbjct: 241 PSLHSLGHPPGPSAVPVPVPGGGGADPLQHHHGLQDSILNPMSANLVDLGS 291
>gi|5174681 SIX homeobox 1 [Homo sapiens]
Length = 284
Score = 435 bits (1118), Expect = e-122
Identities = 222/300 (74%), Positives = 247/300 (82%), Gaps = 25/300 (8%)
Query: 1 MSMLPTFGFTQEQVACVCEVLQQGGNIERLGRFLWSLPACEHLHKNESVLKAKAVVAFHR 60
MSMLP+FGFTQEQVACVCEVLQQGGN+ERLGRFLWSLPAC+HLHKNESVLKAKAVVAFHR
Sbjct: 1 MSMLPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHR 60
Query: 61 GNFRELYKILESHQFSPHNHAKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRS 120
GNFRELYKILESHQFSPHNH KLQQLWLKAHY+EAEKLRGRPLGAVGKYRVRRKFPLPR+
Sbjct: 61 GNFRELYKILESHQFSPHNHPKLQQLWLKAHYVEAEKLRGRPLGAVGKYRVRRKFPLPRT 120
Query: 121 IWDGEETSYCFKEKSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDR 180
IWDGEETSYCFKEKSR VLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDR
Sbjct: 121 IWDGEETSYCFKEKSRGVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDR 180
Query: 181 AAEAKERENNENSNSNSH-----NPLNGSGKSVLGSSEDEKTPSGTPDHSSSSPALLLSP 235
AAEAKEREN EN+NS+S+ +PL G GK ++ SSE+E +P +PD +S LLL
Sbjct: 181 AAEAKERENTENNNSSSNKQNQLSPLEG-GKPLMSSSEEEFSPPQSPDQNS---VLLLQ- 235
Query: 236 PPPGLPSLHSLGHPPGPSAVPVPVPGGGGADPLQ----HHHGLQDSILNPMSANLVDLGS 291
++GH + +PG + P H H LQDS+L P++++LVDLGS
Sbjct: 236 --------GNMGHARSSN---YSLPGLTASQPSHGLQTHQHQLQDSLLGPLTSSLVDLGS 284
>gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]
Length = 332
Score = 289 bits (740), Expect = 2e-78
Identities = 142/232 (61%), Positives = 177/232 (76%), Gaps = 5/232 (2%)
Query: 1 MSMLPTFGFTQEQVACVCEVLQQGGNIERLGRFLWSLP----ACEHLHKNESVLKAKAVV 56
M LPT F+ EQVA VCE L++ G+IERLGRFLWSLP ACE ++K+ES+L+A+AVV
Sbjct: 79 MFQLPTLNFSPEQVASVCETLEETGDIERLGRFLWSLPVAPGACEAINKHESILRARAVV 138
Query: 57 AFHRGNFRELYKILESHQFSPHNHAKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFP 116
AFH GNFR+LY ILE+H+F+ +H KLQ +WL+AHY EAEKLRGRPLG V KYRVR+KFP
Sbjct: 139 AFHTGNFRDLYHILENHKFTKESHGKLQAMWLEAHYQEAEKLRGRPLGPVDKYRVRKKFP 198
Query: 117 LPRSIWDGEETSYCFKEKSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRR 176
LPR+IWDGE+ ++CFKE++RS+LREWY +PYP+P +KRELA+ATGLT TQV NWFKNRR
Sbjct: 199 LPRTIWDGEQKTHCFKERTRSLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRR 258
Query: 177 QRDRAAEAKERENNENSNSNSHNPLNGSGKSVLGSSEDEKTPSGTPDHSSSS 228
QRDRAA AK R ++ + L G GS+E T + +P S SS
Sbjct: 259 QRDRAAAAKNRLQHQAIGPSGMRSLAEPGCPTHGSAESPST-AASPTTSVSS 309
>gi|186910311 SIX homeobox 6 [Homo sapiens]
Length = 246
Score = 285 bits (729), Expect = 3e-77
Identities = 143/240 (59%), Positives = 176/240 (73%), Gaps = 19/240 (7%)
Query: 1 MSMLPTFGFTQEQVACVCEVLQQGGNIERLGRFLWSLP----ACEHLHKNESVLKAKAVV 56
M LP F+ +QVA VCE L++ G++ERLGRFLWSLP ACE L+KNESVL+A+A+V
Sbjct: 1 MFQLPILNFSPQQVAGVCETLEESGDVERLGRFLWSLPVAPAACEALNKNESVLRARAIV 60
Query: 57 AFHRGNFRELYKILESHQFSPHNHAKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFP 116
AFH GN+RELY ILE+H+F+ +HAKLQ LWL+AHY EAEKLRGRPLG V KYRVR+KFP
Sbjct: 61 AFHGGNYRELYHILENHKFTKESHAKLQALWLEAHYQEAEKLRGRPLGPVDKYRVRKKFP 120
Query: 117 LPRSIWDGEETSYCFKEKSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRR 176
LPR+IWDGE+ ++CFKE++R +LREWY +PYP+P +KRELA+ATGLT TQV NWFKNRR
Sbjct: 121 LPRTIWDGEQKTHCFKERTRHLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRR 180
Query: 177 QRDRAAEAKERENNENSNSNSHNPLNGSGKSVLGSSEDEKTPSGTPD--HSSSSPALLLS 234
QRDRAA AK R + + S L G GTP+ ++SPA LS
Sbjct: 181 QRDRAAAAKNRLQQQVLSQGSGRALRAEG-------------DGTPEVLGVATSPAASLS 227
>gi|142976638 sine oculis homeobox homolog 4 [Homo sapiens]
Length = 781
Score = 261 bits (668), Expect = 4e-70
Identities = 133/223 (59%), Positives = 156/223 (69%), Gaps = 10/223 (4%)
Query: 9 FTQEQVACVCEVLQQGGNIERLGRFLWSLPACEHLHKNESVLKAKAVVAFHRGNFRELYK 68
F+ + VACVCE LQQGGN++RL RFLWSLP + L NES+LKA+A+VAFH+G + ELY
Sbjct: 108 FSPDHVACVCEALQQGGNLDRLARFLWSLPQSDLLRGNESLLKARALVAFHQGIYPELYS 167
Query: 69 ILESHQFSPHNHAKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRSIWDGEETS 128
ILESH F NH LQQLW KA Y EAE+ RGRPLGAV KYR+RRKFPLPR+IWDGEET
Sbjct: 168 ILESHSFESANHPLLQQLWYKARYTEAERARGRPLGAVDKYRLRRKFPLPRTIWDGEETV 227
Query: 129 YCFKEKSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDR-------A 181
YCFKEKSR+ L+E Y N YPSP EKR LA+ TGL+ TQVSNWFKNRRQRDR
Sbjct: 228 YCFKEKSRNALKELYKQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDRNPSETQSK 287
Query: 182 AEAKERENNENSNSNSHNPLNGSGKSVLGSSEDEKTPSGTPDH 224
+E+ + E+ +S H L+ L SS D T H
Sbjct: 288 SESDGNPSTEDESSKGHEDLS---PHPLSSSSDGITNLSLSSH 327
>gi|40354216 sine oculis homeobox homolog 5 [Homo sapiens]
Length = 739
Score = 230 bits (587), Expect = 1e-60
Identities = 135/289 (46%), Positives = 173/289 (59%), Gaps = 31/289 (10%)
Query: 9 FTQEQVACVCEVLQQGGNIERLGRFLWSLPACEHLHKNESVLKAKAVVAFHRGNFRELYK 68
F+ EQVACVCE L Q G+ RL RFL +LP E L ++ VL+A+A+VAF RG + ELY+
Sbjct: 86 FSPEQVACVCEALLQAGHAGRLSRFLGALPPAERLRGSDPVLRARALVAFQRGEYAELYR 145
Query: 69 ILESHQFSPHNHAKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRSIWDGEETS 128
+LES F +HA LQ L+L+A Y EAE+ RGR LGAV KYR+R+KFPLP++IWDGEET
Sbjct: 146 LLESRPFPAAHHAFLQDLYLRARYHEAERARGRALGAVDKYRLRKKFPLPKTIWDGEETV 205
Query: 129 YCFKEKSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRA------- 181
YCFKE+SR+ L+ Y N YP+P EKR LA TGL+ TQVSNWFKNRRQRDR
Sbjct: 206 YCFKERSRAALKACYRGNRYPTPDEKRRLATLTGLSLTQVSNWFKNRRQRDRTGAGGGAP 265
Query: 182 --AEAKERENNENSNSNSHNPLNGSGKSVLGSSEDEKT--------PSGTPDHS------ 225
+E+ E+ +S S L V + + + P+ P S
Sbjct: 266 CKSESDGNPTTEDESSRSPEDLERGAAPVSAEAAAQGSIFLAGTGPPAPCPASSSILVNG 325
Query: 226 -----SSSPALLLSPPPPGLPSLHSLGHPPGPSAVPVPVPGGGGADPLQ 269
S SPA+LL+ P + L +LG S P+ + GGGGA P Q
Sbjct: 326 SFLAASGSPAVLLNGGPVIINGL-ALGE--ASSLGPLLLTGGGGAPPPQ 371
>gi|15149472 pre-B-cell leukemia homeobox 4 [Homo sapiens]
Length = 374
Score = 60.1 bits (144), Expect = 2e-09
Identities = 48/154 (31%), Positives = 63/154 (40%), Gaps = 22/154 (14%)
Query: 131 FKEKSRSVLREW-YAH--NPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKER 187
F +++ VL E+ Y+H NPYPS K ELA GLT +QVSNWF N+R R + K +
Sbjct: 217 FSKQATEVLNEYFYSHLNNPYPSEEAKEELARKGGLTISQVSNWFGNKRIRYKKNMGKFQ 276
Query: 188 ENNENSNSNSHNPLNGSGKSVLGSSEDEKTPSGTPDHSSSSPALLLS------------- 234
E + + + +G + + TP SS P L S
Sbjct: 277 E-----EATIYTGKTAVDTTEVGVPGNHASCLSTPSSGSSGPFPLPSAGDAFLTLRTLAS 331
Query: 235 -PPPPGLPSLHSLGHPPGPSAVPVPVPGGGGADP 267
PPPG L S A P P DP
Sbjct: 332 LQPPPGGGCLQSQAQGSWQGATPQPATASPAGDP 365
>gi|46249382 paired-like homeobox 2a [Homo sapiens]
Length = 284
Score = 57.4 bits (137), Expect = 1e-08
Identities = 46/145 (31%), Positives = 60/145 (41%), Gaps = 22/145 (15%)
Query: 139 LREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENNENSNSNSH 198
L +A YP + ELA LT +V WF+NRR + R +ER + + +
Sbjct: 105 LERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR---KQERAASAKGAAGAA 161
Query: 199 NPLNGSGKSVLGSSEDEKTPSGTPDHSSSSPALLLSPPPPGLPSLH--------SLGHPP 250
G + SSED+ + T + S A L PP PGL S +LG P
Sbjct: 162 GAKKGEARC---SSEDDDSKESTCSPTPDSTASLPPPPAPGLASPRLSPSPLPVALGSGP 218
Query: 251 GPSAVPVP--------VPGGGGADP 267
GP P P V GGGG P
Sbjct: 219 GPGPGPQPLKGALWAGVAGGGGGGP 243
>gi|27436887 pre-B-cell leukemia homeobox 2 [Homo sapiens]
Length = 430
Score = 54.7 bits (130), Expect = 9e-08
Identities = 43/141 (30%), Positives = 62/141 (43%), Gaps = 9/141 (6%)
Query: 131 FKEKSRSVLREW-YAH--NPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAK-E 186
F +++ VL E+ Y+H NPYPS K ELA+ G+T +QVSNWF N+R R + K +
Sbjct: 251 FSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQ 310
Query: 187 RENNENSNSNSHNPLNGSGKSVLGSSEDEKTPSGTPDHSSSSPALLLSPP-----PPGLP 241
E N + + + G + SG + S S + L P
Sbjct: 311 EEANIYAVKTAVSVTQGGHSRTSSPTPPSSAGSGGSFNLSGSGDMFLGMPGLNGDSYSAS 370
Query: 242 SLHSLGHPPGPSAVPVPVPGG 262
+ SL H GP + GG
Sbjct: 371 QVESLRHSMGPGGYGDNLGGG 391
>gi|4505623 pre-B-cell leukemia homeobox 1 [Homo sapiens]
Length = 430
Score = 54.3 bits (129), Expect = 1e-07
Identities = 41/119 (34%), Positives = 64/119 (53%), Gaps = 8/119 (6%)
Query: 131 FKEKSRSVLREW-YAH--NPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKER 187
F +++ +L E+ Y+H NPYPS K ELA+ G+T +QVSNWF N+R R + K +
Sbjct: 240 FNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQ 299
Query: 188 ENNENSNSNSHNPLNGSGKSVLGSSEDEKTPSGTPDHSSSSPALLLSPPPPGLPSLHSL 246
E E + + + + S GS + +PS TP+ + SS + +S S+ SL
Sbjct: 300 E--EANIYAAKTAVTATNVSAHGSQAN--SPS-TPNSAGSSSSFNMSNSGDLFMSVQSL 353
>gi|198041755 pre-B-cell leukemia homeobox 3 isoform 2 [Homo
sapiens]
Length = 359
Score = 53.1 bits (126), Expect = 3e-07
Identities = 34/101 (33%), Positives = 55/101 (54%), Gaps = 6/101 (5%)
Query: 131 FKEKSRSVLREW-YAH--NPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKER 187
F +++ +L E+ Y+H NPYPS K ELA+ +T +QVSNWF N+R R + K +
Sbjct: 167 FSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKFQ 226
Query: 188 ENNENSNSNSHNPLNGSGKSVLGSSEDEKTPSGTPDHSSSS 228
E +N + + +V + ++ +T S T +S SS
Sbjct: 227 ---EEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGSS 264
>gi|5453852 pre-B-cell leukemia homeobox 3 isoform 1 [Homo sapiens]
Length = 434
Score = 53.1 bits (126), Expect = 3e-07
Identities = 34/101 (33%), Positives = 55/101 (54%), Gaps = 6/101 (5%)
Query: 131 FKEKSRSVLREW-YAH--NPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKER 187
F +++ +L E+ Y+H NPYPS K ELA+ +T +QVSNWF N+R R + K +
Sbjct: 242 FSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKFQ 301
Query: 188 ENNENSNSNSHNPLNGSGKSVLGSSEDEKTPSGTPDHSSSS 228
E +N + + +V + ++ +T S T +S SS
Sbjct: 302 ---EEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGSS 339
>gi|34328941 TGFB-induced factor homeobox 2-like, X-linked [Homo
sapiens]
Length = 241
Score = 52.0 bits (123), Expect = 6e-07
Identities = 39/126 (30%), Positives = 57/126 (45%), Gaps = 9/126 (7%)
Query: 134 KSRSVLREW-YAHN--PYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENN 190
+S +LR+W Y H YPS EK+ L+E T L+ Q+SNWF N R+R ++R N+
Sbjct: 60 ESVKILRDWMYKHRFKAYPSEEEKQMLSEKTNLSLLQISNWFINARRRILPDMLQQRRND 119
Query: 191 ENSNSNSHNPLNGSGKSVLGSSEDEKTPSGTPDHSSSSPALLLSPPPPGLPSLHSLGHPP 250
+ + + +S K+ PD+ S P L P P G S P
Sbjct: 120 PIIGHKTGKDAHATHLQSTEASVPAKSGPSGPDNVQSLP---LWPLPKGQMSREK---QP 173
Query: 251 GPSAVP 256
P + P
Sbjct: 174 DPESAP 179
>gi|24762250 Meis homeobox 2 isoform d [Homo sapiens]
Length = 470
Score = 52.0 bits (123), Expect = 6e-07
Identities = 50/183 (27%), Positives = 79/183 (43%), Gaps = 33/183 (18%)
Query: 131 FKEKSRSVLREW---YAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQR--------- 178
F + + +++R W + +PYPS +K++LA+ TGLT QV+NWF N R+R
Sbjct: 283 FPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQS 342
Query: 179 DRAAEAKERENNENS-------NSNSHNPLNGSG-KSVLGSSEDEKTPSGTPDHSSSSPA 230
+RA + E + H + +G +S+ G + P G S
Sbjct: 343 NRAVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPMGMSMAQPSYTP 402
Query: 231 LLLSPPPPGL---PSLHSL--GHPPGPSAVPVPVPGGGGADPLQHHHGLQDSILNPMSAN 285
++P P L P +HS HP P+ + + GG H G+ S +P N
Sbjct: 403 PQMTPHPTQLRHGPPMHSYLPSHPHHPAMM---MHGGPPT-----HPGMTMSAQSPTMLN 454
Query: 286 LVD 288
VD
Sbjct: 455 SVD 457
>gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens]
Length = 1505
Score = 51.2 bits (121), Expect = 1e-06
Identities = 41/155 (26%), Positives = 57/155 (36%), Gaps = 23/155 (14%)
Query: 134 KSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKE--RENNE 191
+ + L+ Y PYPSP+ +LA L T+ V NWF N R R R E + ++
Sbjct: 1254 EEKEALKRAYQQKPYPSPKTIEDLATQLNLKTSTVINWFHNYRSRIRRELFIEEIQAGSQ 1313
Query: 192 NSNSNSHNPLNGSGKSVLGS------------------SEDEKTPSGTPDHSSSSPALLL 233
S +P SG++ S +E+ K+ PA
Sbjct: 1314 GQAGASDSPSARSGRAAPSSEGDSCDGVEATEGPGSADTEEPKSQGEAEREEVPRPAEQT 1373
Query: 234 SPPPPGLP---SLHSLGHPPGPSAVPVPVPGGGGA 265
PPP G P H GP P P+P A
Sbjct: 1374 EPPPSGTPGPDDARDDDHEGGPVEGPGPLPSPASA 1408
>gi|4505151 Meis homeobox 1 [Homo sapiens]
Length = 390
Score = 50.8 bits (120), Expect = 1e-06
Identities = 26/73 (35%), Positives = 42/73 (57%), Gaps = 4/73 (5%)
Query: 131 FKEKSRSVLREW---YAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKER 187
F + + +++R W + +PYPS +K++LA+ TGLT QV+NWF N R+R ++
Sbjct: 279 FPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR-IVQPMIDQ 337
Query: 188 ENNENSNSNSHNP 200
N S +NP
Sbjct: 338 SNRAVSQGTPYNP 350
>gi|57863281 Meis1, myeloid ecotropic viral integration site 1
homolog 3 isoform 1 [Homo sapiens]
Length = 421
Score = 50.8 bits (120), Expect = 1e-06
Identities = 20/37 (54%), Positives = 28/37 (75%)
Query: 142 WYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQR 178
W+ +PYPS +K++LA+ TGLT QV+NWF N R+R
Sbjct: 329 WWLQHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 365
>gi|57863279 Meis1, myeloid ecotropic viral integration site 1
homolog 3 isoform 2 [Homo sapiens]
Length = 358
Score = 50.4 bits (119), Expect = 2e-06
Identities = 22/51 (43%), Positives = 35/51 (68%), Gaps = 3/51 (5%)
Query: 131 FKEKSRSVLREW---YAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQR 178
F + + +++R W + +PYPS +K++LA+ TGLT QV+NWF N R+R
Sbjct: 252 FPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 302
>gi|27502383 Meis homeobox 2 isoform h [Homo sapiens]
Length = 306
Score = 50.1 bits (118), Expect = 2e-06
Identities = 22/51 (43%), Positives = 35/51 (68%), Gaps = 3/51 (5%)
Query: 131 FKEKSRSVLREW---YAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQR 178
F + + +++R W + +PYPS +K++LA+ TGLT QV+NWF N R+R
Sbjct: 195 FPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 245
>gi|27502381 Meis homeobox 2 isoform g [Homo sapiens]
Length = 388
Score = 50.1 bits (118), Expect = 2e-06
Identities = 22/51 (43%), Positives = 35/51 (68%), Gaps = 3/51 (5%)
Query: 131 FKEKSRSVLREW---YAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQR 178
F + + +++R W + +PYPS +K++LA+ TGLT QV+NWF N R+R
Sbjct: 270 FPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 320
>gi|24762244 Meis homeobox 2 isoform a [Homo sapiens]
Length = 401
Score = 50.1 bits (118), Expect = 2e-06
Identities = 22/51 (43%), Positives = 35/51 (68%), Gaps = 3/51 (5%)
Query: 131 FKEKSRSVLREW---YAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQR 178
F + + +++R W + +PYPS +K++LA+ TGLT QV+NWF N R+R
Sbjct: 283 FPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 333
>gi|24762241 Meis homeobox 2 isoform c [Homo sapiens]
Length = 477
Score = 50.1 bits (118), Expect = 2e-06
Identities = 22/51 (43%), Positives = 35/51 (68%), Gaps = 3/51 (5%)
Query: 131 FKEKSRSVLREW---YAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQR 178
F + + +++R W + +PYPS +K++LA+ TGLT QV+NWF N R+R
Sbjct: 283 FPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 333
>gi|24762246 Meis homeobox 2 isoform b [Homo sapiens]
Length = 394
Score = 50.1 bits (118), Expect = 2e-06
Identities = 22/51 (43%), Positives = 35/51 (68%), Gaps = 3/51 (5%)
Query: 131 FKEKSRSVLREW---YAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQR 178
F + + +++R W + +PYPS +K++LA+ TGLT QV+NWF N R+R
Sbjct: 283 FPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 333
>gi|24762225 Meis homeobox 2 isoform f [Homo sapiens]
Length = 381
Score = 50.1 bits (118), Expect = 2e-06
Identities = 22/51 (43%), Positives = 35/51 (68%), Gaps = 3/51 (5%)
Query: 131 FKEKSRSVLREW---YAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQR 178
F + + +++R W + +PYPS +K++LA+ TGLT QV+NWF N R+R
Sbjct: 270 FPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 320
>gi|139394646 iroquois homeobox protein 5 [Homo sapiens]
Length = 483
Score = 50.1 bits (118), Expect = 2e-06
Identities = 48/169 (28%), Positives = 67/169 (39%), Gaps = 37/169 (21%)
Query: 137 SVLREW---YAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQ------------RDRA 181
+ L+ W + NPYP+ EK LA T +T TQVS WF N R+ R+R+
Sbjct: 126 ATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWTPRNRS 185
Query: 182 AEAKERENNENSNSNSHNPLNGSGKS-----VLGSSEDE-----------KTPSGTPDHS 225
+ +E EN + ++ P K G +E + TP+G
Sbjct: 186 EDEEEEENIDLEKNDEDEPQKPEDKGDPEGPEAGGAEQKAASGCERLQGPPTPAGKETEG 245
Query: 226 SSSPALLLSPPPPGLPSLHSLGHPP---GPSAVPVPVPGGGGADPLQHH 271
S S + PP G L +L PP GPS P DP H+
Sbjct: 246 SLSDSDFKEPPSEG--RLDALQGPPRTGGPSPAG-PAAARLAEDPAPHY 291
>gi|7110735 ventral anterior homeobox 2 [Homo sapiens]
Length = 290
Score = 48.5 bits (114), Expect = 7e-06
Identities = 38/125 (30%), Positives = 61/125 (48%), Gaps = 13/125 (10%)
Query: 148 YPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENNENSNSNSHNPLNGSGKS 207
Y RE+ ELA L+ TQV WF+NRR + + ++++ E +S+++ + +
Sbjct: 126 YVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSASE----AFATSN 181
Query: 208 VLGSSEDEKTPSGTPDHSSSSPALL-LSPPPPGLPSLH---SLGHPPGPSAVPVPVPGGG 263
+L E + S +P+LL L+P PGLP+ H SLG P S P+
Sbjct: 182 ILRLLEQGRLLS-----VPRAPSLLALTPSLPGLPASHRGTSLGDPRNSSPRLNPLSSAS 236
Query: 264 GADPL 268
+ PL
Sbjct: 237 ASPPL 241
>gi|239751129 PREDICTED: hypothetical protein XP_002347726 [Homo
sapiens]
Length = 345
Score = 48.1 bits (113), Expect = 9e-06
Identities = 17/71 (23%), Positives = 38/71 (53%), Gaps = 3/71 (4%)
Query: 131 FKEKSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAK---ER 187
+ + + +L+ W+ H+P+P + +LA+ G+ + + WFKN R + R + K E+
Sbjct: 22 YNQSQKDILQSWFQHDPFPDKAAREQLAKEIGVPESNIQVWFKNYRVKQRKLDYKCFSEK 81
Query: 188 ENNENSNSNSH 198
+ + + + H
Sbjct: 82 DQTQGHDQSQH 92
Score = 36.6 bits (83), Expect = 0.027
Identities = 24/99 (24%), Positives = 51/99 (51%), Gaps = 11/99 (11%)
Query: 85 QLWLKAHYIEAEKL-------RGRPLGAVGKYRVRRKFPLPRSIWDGEETSYCFKEKSRS 137
Q+W K + ++ KL + + G + +++ LP+ ++T + +K+R
Sbjct: 60 QVWFKNYRVKQRKLDYKCFSEKDQTQGHDQSQHLTQEY-LPKEARQ-KQTFITWTQKNRL 117
Query: 138 VLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRR 176
V + + NP+P +++LAE TGL +++ WF+ +R
Sbjct: 118 V--QAFERNPFPDIATRKKLAEQTGLQESRIQMWFQKQR 154
>gi|239745620 PREDICTED: hypothetical protein XP_002344158 [Homo
sapiens]
Length = 345
Score = 48.1 bits (113), Expect = 9e-06
Identities = 17/71 (23%), Positives = 38/71 (53%), Gaps = 3/71 (4%)
Query: 131 FKEKSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAK---ER 187
+ + + +L+ W+ H+P+P + +LA+ G+ + + WFKN R + R + K E+
Sbjct: 22 YNQSQKDILQSWFQHDPFPDKAAREQLAKEIGVPESNIQVWFKNYRVKQRKLDYKCFSEK 81
Query: 188 ENNENSNSNSH 198
+ + + + H
Sbjct: 82 DQTQGHDQSQH 92
Score = 36.6 bits (83), Expect = 0.027
Identities = 24/99 (24%), Positives = 51/99 (51%), Gaps = 11/99 (11%)
Query: 85 QLWLKAHYIEAEKL-------RGRPLGAVGKYRVRRKFPLPRSIWDGEETSYCFKEKSRS 137
Q+W K + ++ KL + + G + +++ LP+ ++T + +K+R
Sbjct: 60 QVWFKNYRVKQRKLDYKCFSEKDQTQGHDQSQHLTQEY-LPKEARQ-KQTFITWTQKNRL 117
Query: 138 VLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRR 176
V + + NP+P +++LAE TGL +++ WF+ +R
Sbjct: 118 V--QAFERNPFPDIATRKKLAEQTGLQESRIQMWFQKQR 154
>gi|28178843 TG-interacting factor isoform a [Homo sapiens]
Length = 401
Score = 47.4 bits (111), Expect = 2e-05
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 12/117 (10%)
Query: 133 EKSRSVLREW---YAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQR----DRAAEAK 185
++S +LR+W + +N YPS +EK L++ T L+T QV NWF N R+R + K
Sbjct: 173 KESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGK 232
Query: 186 ERENNENSNSNSHNPLNGSGKSVLGSSEDEKTPSGTPDHSSS---SPAL--LLSPPP 237
+ S + S +SV+G TP HS + +P L LSP P
Sbjct: 233 DPNQFTISRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNPTLGRPLSPKP 289
>gi|4507473 TG-interacting factor isoform c [Homo sapiens]
Length = 272
Score = 47.4 bits (111), Expect = 2e-05
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 12/117 (10%)
Query: 133 EKSRSVLREW---YAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQR----DRAAEAK 185
++S +LR+W + +N YPS +EK L++ T L+T QV NWF N R+R + K
Sbjct: 44 KESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGK 103
Query: 186 ERENNENSNSNSHNPLNGSGKSVLGSSEDEKTPSGTPDHSSS---SPAL--LLSPPP 237
+ S + S +SV+G TP HS + +P L LSP P
Sbjct: 104 DPNQFTISRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNPTLGRPLSPKP 160
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,596,040
Number of Sequences: 37866
Number of extensions: 917608
Number of successful extensions: 7643
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 434
Number of HSP's successfully gapped in prelim test: 446
Number of HSP's that attempted gapping in prelim test: 5356
Number of HSP's gapped (non-prelim): 2444
length of query: 291
length of database: 18,247,518
effective HSP length: 101
effective length of query: 190
effective length of database: 14,423,052
effective search space: 2740379880
effective search space used: 2740379880
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.