Search of human proteins with 21918872

Search of human proteins with 21918872

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21918872 lactation elevated 1 [Homo sapiens]
         (481 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21918872 lactation elevated 1 [Homo sapiens]                       972   0.0  
gi|6005942 valosin-containing protein [Homo sapiens]                   33   0.57 
gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]    32   0.98 
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]      32   1.3  
gi|194018482 NLR family, pyrin domain containing 4 [Homo sapiens]      32   1.7  
gi|157671927 spermatogenesis associated 5 [Homo sapiens]               31   2.2  
gi|4505725 peroxin1 [Homo sapiens]                                     31   2.9  
gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]             31   2.9  
gi|145275216 kinesin family member 2B [Homo sapiens]                   30   4.9  
gi|187608784 transmembrane channel-like 6 [Homo sapiens]               30   4.9  
gi|187608791 transmembrane channel-like 6 [Homo sapiens]               30   4.9  
gi|31542661 transmembrane protein 57 [Homo sapiens]                    30   6.4  
gi|14149653 torsin family 1, member B (torsin B) [Homo sapiens]        30   6.4  
gi|31377644 ATPase family, AAA domain containing 1 [Homo sapiens]      30   6.4  
gi|4503231 cytochrome P450, family 3, subfamily A, polypeptide 5...    29   8.3  
gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]             29   8.3  
gi|134288890 DIS3 mitotic control homolog (S. cerevisiae)-like 2...    29   8.3  
gi|24371268 nucleosome assembly protein 1-like 5 [Homo sapiens]        29   8.3  

>gi|21918872 lactation elevated 1 [Homo sapiens]
          Length = 481

 Score =  972 bits (2512), Expect = 0.0
 Identities = 481/481 (100%), Positives = 481/481 (100%)

Query: 1   MAASWSLLVTLRPLAQSPLRGRCVGCGAWAAALAPLATAPGKPFWKAYTVQTSESMTPTA 60
           MAASWSLLVTLRPLAQSPLRGRCVGCGAWAAALAPLATAPGKPFWKAYTVQTSESMTPTA
Sbjct: 1   MAASWSLLVTLRPLAQSPLRGRCVGCGAWAAALAPLATAPGKPFWKAYTVQTSESMTPTA 60

Query: 61  TSETYLKALAVCHGPLDHYDFLIKAHELKDDEHQRRVIQCLQKLHEDLKGYNIEAEGLFS 120
           TSETYLKALAVCHGPLDHYDFLIKAHELKDDEHQRRVIQCLQKLHEDLKGYNIEAEGLFS
Sbjct: 61  TSETYLKALAVCHGPLDHYDFLIKAHELKDDEHQRRVIQCLQKLHEDLKGYNIEAEGLFS 120

Query: 121 KLFSRSKPPRGLYVYGDVGTGKTMVMDMFYAYVEMKRKKRVHFHGFMLDVHKRIHRLKQS 180
           KLFSRSKPPRGLYVYGDVGTGKTMVMDMFYAYVEMKRKKRVHFHGFMLDVHKRIHRLKQS
Sbjct: 121 KLFSRSKPPRGLYVYGDVGTGKTMVMDMFYAYVEMKRKKRVHFHGFMLDVHKRIHRLKQS 180

Query: 181 LPKRKPGFMAKSYDPIAPIAEEISEEACLLCFDEFQVTDIADAMILKQLFENLFKNGVVV 240
           LPKRKPGFMAKSYDPIAPIAEEISEEACLLCFDEFQVTDIADAMILKQLFENLFKNGVVV
Sbjct: 181 LPKRKPGFMAKSYDPIAPIAEEISEEACLLCFDEFQVTDIADAMILKQLFENLFKNGVVV 240

Query: 241 VATSNRPPEDLYKNGLQRANFVPFIAVLKEYCNTVQLDSGIDYRKRELPAAGKLYYLTSE 300
           VATSNRPPEDLYKNGLQRANFVPFIAVLKEYCNTVQLDSGIDYRKRELPAAGKLYYLTSE
Sbjct: 241 VATSNRPPEDLYKNGLQRANFVPFIAVLKEYCNTVQLDSGIDYRKRELPAAGKLYYLTSE 300

Query: 301 ADVEAVMDKLFDELAQKQNDLTRPRILKVQGRELRLNKACGTVADCTFEELCERPLGASD 360
           ADVEAVMDKLFDELAQKQNDLTRPRILKVQGRELRLNKACGTVADCTFEELCERPLGASD
Sbjct: 301 ADVEAVMDKLFDELAQKQNDLTRPRILKVQGRELRLNKACGTVADCTFEELCERPLGASD 360

Query: 361 YLELSKNFDTIFLRNIPQFTLANRTQGRRFITLIDNFYDLKVRIICSASTPISSLFLHQH 420
           YLELSKNFDTIFLRNIPQFTLANRTQGRRFITLIDNFYDLKVRIICSASTPISSLFLHQH
Sbjct: 361 YLELSKNFDTIFLRNIPQFTLANRTQGRRFITLIDNFYDLKVRIICSASTPISSLFLHQH 420

Query: 421 HDSELEQSRILMDDLGLSQDSAEGLSMFTGEEEIFAFQRTISRLTEMQTEQYWNEGDRTK 480
           HDSELEQSRILMDDLGLSQDSAEGLSMFTGEEEIFAFQRTISRLTEMQTEQYWNEGDRTK
Sbjct: 421 HDSELEQSRILMDDLGLSQDSAEGLSMFTGEEEIFAFQRTISRLTEMQTEQYWNEGDRTK 480

Query: 481 K 481
           K
Sbjct: 481 K 481


>gi|6005942 valosin-containing protein [Homo sapiens]
          Length = 806

 Score = 33.1 bits (74), Expect = 0.57
 Identities = 12/19 (63%), Positives = 16/19 (84%)

Query: 127 KPPRGLYVYGDVGTGKTMV 145
           KPPRG+ +YG  GTGKT++
Sbjct: 236 KPPRGILLYGPPGTGKTLI 254


>gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]
          Length = 1458

 Score = 32.3 bits (72), Expect = 0.98
 Identities = 15/30 (50%), Positives = 20/30 (66%), Gaps = 2/30 (6%)

Query: 118 LFSKLFSRSK--PPRGLYVYGDVGTGKTMV 145
           L+ ++F + K  PPRG   YG  GTGKT+V
Sbjct: 421 LYPEIFEKFKIQPPRGCLFYGPPGTGKTLV 450


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 15/30 (50%), Positives = 20/30 (66%), Gaps = 2/30 (6%)

Query: 118 LFSKLFSRSK--PPRGLYVYGDVGTGKTMV 145
           L+ ++F + K  PPRG   YG  GTGKT+V
Sbjct: 447 LYPEVFEKFKIQPPRGCLFYGPPGTGKTLV 476


>gi|194018482 NLR family, pyrin domain containing 4 [Homo sapiens]
          Length = 994

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 7/93 (7%)

Query: 127 KPPRGLYVYGDVGTGK-TMVMDMFYAYVEMKRKKRVHFHGFMLDVHKRIHRLKQSLPKRK 185
           K PR + + G  G GK T++M +  A+ + K    +    F+   +     L++  P   
Sbjct: 146 KQPRTVIIQGPQGIGKTTLLMKLMMAWSDNK----IFRDRFLYTFYFCCRELRELPPTSL 201

Query: 186 PGFMAKSY-DPIAPIAEEISE-EACLLCFDEFQ 216
              +++ + DP API E +S+ E  L   D F+
Sbjct: 202 ADLISREWPDPAAPITEIVSQPERLLFVIDSFE 234


>gi|157671927 spermatogenesis associated 5 [Homo sapiens]
          Length = 893

 Score = 31.2 bits (69), Expect = 2.2
 Identities = 19/51 (37%), Positives = 24/51 (47%), Gaps = 13/51 (25%)

Query: 95  RRVIQCLQKLHEDLKGYNIEAEGLFSKLFSRSKPPRGLYVYGDVGTGKTMV 145
           R +I+   K  E  K Y I A             PRG+ +YG  GTGKTM+
Sbjct: 366 REIIELPLKQPELFKSYGIPA-------------PRGVLLYGPPGTGKTMI 403


>gi|4505725 peroxin1 [Homo sapiens]
          Length = 1283

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 36/143 (25%), Positives = 60/143 (41%), Gaps = 34/143 (23%)

Query: 118 LFSKLFSRSKPPRGLYVYGDVGTGKTMVMDMFYAYVEMKRKKRVHFHGFMLDVHKRIHRL 177
           LF+ L  R +   G+ +YG  GTGKT++  +      + R+ R++F             +
Sbjct: 865 LFANLPIRQRT--GILLYGPPGTGKTLLAGV------IARESRMNF-------------I 903

Query: 178 KQSLPKRKPGFMAKSYDPIAPI-AEEISEEACLLCFDEFQ------------VTDIADAM 224
               P+    ++  S   +  I     + + C+L FDEF+            VTD     
Sbjct: 904 SVKGPELLSKYIGASEQAVRDIFIRAQAAKPCILFFDEFESIAPRRGHDNTGVTDRVVNQ 963

Query: 225 ILKQLFENLFKNGVVVVATSNRP 247
           +L QL       GV V+A ++RP
Sbjct: 964 LLTQLDGVEGLQGVYVLAATSRP 986


>gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]
          Length = 440

 Score = 30.8 bits (68), Expect = 2.9
 Identities = 11/19 (57%), Positives = 16/19 (84%)

Query: 127 KPPRGLYVYGDVGTGKTMV 145
           KPP+G+ +YG  GTGKT++
Sbjct: 217 KPPKGVILYGPPGTGKTLL 235


>gi|145275216 kinesin family member 2B [Homo sapiens]
          Length = 673

 Score = 30.0 bits (66), Expect = 4.9
 Identities = 26/97 (26%), Positives = 37/97 (38%), Gaps = 13/97 (13%)

Query: 58  PTATSETYLKALAVCHGPLDHYDFLIKAHELKDDEHQRRVIQ----CLQKLHEDLKG--- 110
           P    ET LK L +   P D+   ++  HE K      R +Q    C     +D      
Sbjct: 222 PLNQRETTLKDLDIITVPSDN---VVMVHESKQKVDLTRYLQNQTFCFDHAFDDKASNEL 278

Query: 111 -YNIEAEGLFSKLFSRSKPPRGLYVYGDVGTGKTMVM 146
            Y   A+ L   +F +       + YG  G+GKT  M
Sbjct: 279 VYQFTAQPLVESIFRKGMAT--CFAYGQTGSGKTYTM 313


>gi|187608784 transmembrane channel-like 6 [Homo sapiens]
          Length = 805

 Score = 30.0 bits (66), Expect = 4.9
 Identities = 32/142 (22%), Positives = 59/142 (41%), Gaps = 20/142 (14%)

Query: 304 EAVMDKLFDELAQKQNDLTRPRILKVQGRELRLNKACGTVADCTFEELCERPLGASDYLE 363
           E+ +   F +L Q+Q+  T    L++Q RE  +  +         ++   RP G      
Sbjct: 27  ESEVHDSFQQLIQEQSQCTAQEGLELQQREREVTGSS--------QQTLWRPEGTQSTAT 78

Query: 364 LSKNFDTIFLRNIPQFTLANRTQGRRFITLIDNFYDLKVRIICSASTPISSLFLHQHHDS 423
           L        L ++P     +RT GR    +I  +Y+  V++ C +S P+   F+     S
Sbjct: 79  LR------ILASMP-----SRTIGRSRGAIISQYYNRTVQLRCRSSRPLLGNFVRSAWPS 127

Query: 424 ELEQSRILMDDLGLSQDSAEGL 445
            L    + +D   L ++  + L
Sbjct: 128 -LRLYDLELDPTALEEEEKQSL 148


>gi|187608791 transmembrane channel-like 6 [Homo sapiens]
          Length = 805

 Score = 30.0 bits (66), Expect = 4.9
 Identities = 32/142 (22%), Positives = 59/142 (41%), Gaps = 20/142 (14%)

Query: 304 EAVMDKLFDELAQKQNDLTRPRILKVQGRELRLNKACGTVADCTFEELCERPLGASDYLE 363
           E+ +   F +L Q+Q+  T    L++Q RE  +  +         ++   RP G      
Sbjct: 27  ESEVHDSFQQLIQEQSQCTAQEGLELQQREREVTGSS--------QQTLWRPEGTQSTAT 78

Query: 364 LSKNFDTIFLRNIPQFTLANRTQGRRFITLIDNFYDLKVRIICSASTPISSLFLHQHHDS 423
           L        L ++P     +RT GR    +I  +Y+  V++ C +S P+   F+     S
Sbjct: 79  LR------ILASMP-----SRTIGRSRGAIISQYYNRTVQLRCRSSRPLLGNFVRSAWPS 127

Query: 424 ELEQSRILMDDLGLSQDSAEGL 445
            L    + +D   L ++  + L
Sbjct: 128 -LRLYDLELDPTALEEEEKQSL 148


>gi|31542661 transmembrane protein 57 [Homo sapiens]
          Length = 664

 Score = 29.6 bits (65), Expect = 6.4
 Identities = 25/107 (23%), Positives = 49/107 (45%), Gaps = 4/107 (3%)

Query: 58  PTATSETYLKALAVCHGPLDHYDFL---IKAHELKDDEHQRRVIQCLQKLHEDLKGYNIE 114
           P+++S+   K       P  H D +   I  ++L   +   R+ Q ++KL  DL+     
Sbjct: 344 PSSSSKNEKKQKCTSKSPSTHKDLMENCIPNNQLSKPDALVRLEQDIKKLKADLQASRQV 403

Query: 115 AEGLFSKLFSRSKPPRGL-YVYGDVGTGKTMVMDMFYAYVEMKRKKR 160
            + L S++ S S   RG+    G +     ++ +  +  V+MK+K +
Sbjct: 404 EQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQKDK 450


>gi|14149653 torsin family 1, member B (torsin B) [Homo sapiens]
          Length = 336

 Score = 29.6 bits (65), Expect = 6.4
 Identities = 28/109 (25%), Positives = 43/109 (39%), Gaps = 5/109 (4%)

Query: 68  ALAVCHGPLDHYDFLIKAHELKDDEHQRRVIQCLQKLHEDLKGYNIEAEGLFSKL--FSR 125
           A +   G L + D   +  E   +E           L E L G ++  E +F  L  F  
Sbjct: 36  AASAITGYLSYNDIYCRFAECCREERPLNASALKLDLEEKLFGQHLATEVIFKALTGFRN 95

Query: 126 SKPPRG---LYVYGDVGTGKTMVMDMFYAYVEMKRKKRVHFHGFMLDVH 171
           +K P+    L ++G  GTGK  V  +    +  K  K    H F+  +H
Sbjct: 96  NKNPKKPLTLSLHGWAGTGKNFVSQIVAENLHPKGLKSNFVHLFVSTLH 144


>gi|31377644 ATPase family, AAA domain containing 1 [Homo sapiens]
          Length = 361

 Score = 29.6 bits (65), Expect = 6.4
 Identities = 29/92 (31%), Positives = 45/92 (48%), Gaps = 12/92 (13%)

Query: 62  SETYLKALAVCHGPLDHYDFLIKAHELKDDEHQRRV---IQCLQKLHEDLKG---YNIEA 115
           +E  +K + V +  L  Y+  I AH L D  +       I  L  +  DLK      I+ 
Sbjct: 55  AEKLMKQIGVKNVKLSEYEMSIAAH-LVDPLNMHVTWSDIAGLDDVITDLKDTVILPIKK 113

Query: 116 EGLF--SKLFSRSKPPRGLYVYGDVGTGKTMV 145
           + LF  S+L    +PP+G+ +YG  G GKT++
Sbjct: 114 KHLFENSRLL---QPPKGVLLYGPPGCGKTLI 142


>gi|4503231 cytochrome P450, family 3, subfamily A, polypeptide 5
           [Homo sapiens]
          Length = 502

 Score = 29.3 bits (64), Expect = 8.3
 Identities = 19/53 (35%), Positives = 25/53 (47%), Gaps = 1/53 (1%)

Query: 104 LHEDLKGYNIEAEGLFSKLFSRSKPPRGLYVYGDVGTGKTMVMDMFYAYVEMK 156
           LH D K Y  E E    + FS+ K     Y+Y   GTG    + M +A + MK
Sbjct: 401 LHHDPK-YWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMK 452


>gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]
          Length = 439

 Score = 29.3 bits (64), Expect = 8.3
 Identities = 10/19 (52%), Positives = 16/19 (84%)

Query: 127 KPPRGLYVYGDVGTGKTMV 145
           +PP+G+ +YG  GTGKT++
Sbjct: 218 QPPKGVLMYGPPGTGKTLL 236


>gi|134288890 DIS3 mitotic control homolog (S. cerevisiae)-like 2
           [Homo sapiens]
          Length = 885

 Score = 29.3 bits (64), Expect = 8.3
 Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 2/57 (3%)

Query: 208 CLLCFDEFQVTDIADAMILKQLFENLFKNGVVVVATSNRPPE--DLYKNGLQRANFV 262
           C+   D     D+ DA+  K L +  FK GV +   S   PE  DL K   +RA  V
Sbjct: 378 CIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSV 434


>gi|24371268 nucleosome assembly protein 1-like 5 [Homo sapiens]
          Length = 182

 Score = 29.3 bits (64), Expect = 8.3
 Identities = 12/28 (42%), Positives = 18/28 (64%)

Query: 303 VEAVMDKLFDELAQKQNDLTRPRILKVQ 330
           +EA  DK F  L +K ND+ +P + K+Q
Sbjct: 94  IEAKFDKEFQALEKKYNDIYKPLLAKIQ 121


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,986,578
Number of Sequences: 37866
Number of extensions: 769811
Number of successful extensions: 2059
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 2048
Number of HSP's gapped (non-prelim): 20
length of query: 481
length of database: 18,247,518
effective HSP length: 106
effective length of query: 375
effective length of database: 14,233,722
effective search space: 5337645750
effective search space used: 5337645750
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.