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Search of human proteins with 217416452
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|217416452 dynein, axonemal, intermediate polypeptide 2 [Homo
sapiens]
(605 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|217416452 dynein, axonemal, intermediate polypeptide 2 [Homo ... 1233 0.0
gi|6912338 dynein, axonemal, intermediate chain 1 [Homo sapiens] 128 2e-29
gi|66267730 WD repeat domain 34 [Homo sapiens] 110 3e-24
gi|217272887 WD repeat domain 63 [Homo sapiens] 108 2e-23
gi|24307879 dynein, cytoplasmic 1, intermediate chain 2 [Homo sa... 103 3e-22
gi|46276887 WD repeat domain 78 isoform 1 [Homo sapiens] 102 8e-22
gi|4758178 dynein, cytoplasmic 1, intermediate chain 1 isoform a... 94 3e-19
gi|207113122 dynein, cytoplasmic 1, intermediate chain 1 isoform... 94 3e-19
gi|207113124 dynein, cytoplasmic 1, intermediate chain 1 isoform... 93 8e-19
gi|116256340 SEC31 homolog A isoform 3 [Homo sapiens] 57 6e-08
gi|116256338 SEC31 homolog A isoform 1 [Homo sapiens] 57 6e-08
gi|116256336 SEC31 homolog A isoform 4 [Homo sapiens] 57 6e-08
gi|41349441 SEC31 homolog A isoform 2 [Homo sapiens] 57 6e-08
gi|41349439 SEC31 homolog A isoform 1 [Homo sapiens] 57 6e-08
gi|14149696 SEC31 homolog B [Homo sapiens] 47 4e-05
gi|58331266 WD repeat domain 59 [Homo sapiens] 47 4e-05
gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens] 47 5e-05
gi|62234461 Notchless gene homolog isoform a [Homo sapiens] 45 3e-04
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 44 3e-04
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 44 3e-04
gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 44 3e-04
gi|155030242 WD repeat domain 60 [Homo sapiens] 44 3e-04
gi|188219762 denticleless homolog [Homo sapiens] 42 0.001
gi|21071067 TBP-associated factor 5 [Homo sapiens] 42 0.001
gi|168229161 coronin 7 [Homo sapiens] 42 0.002
gi|53759148 retinoblastoma binding protein 5 [Homo sapiens] 42 0.002
gi|8922301 WD repeat domain 70 [Homo sapiens] 41 0.003
gi|21541824 transducin-like enhancer protein 1 [Homo sapiens] 40 0.005
gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens] 40 0.005
gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens] 40 0.005
>gi|217416452 dynein, axonemal, intermediate polypeptide 2 [Homo
sapiens]
Length = 605
Score = 1233 bits (3191), Expect = 0.0
Identities = 605/605 (100%), Positives = 605/605 (100%)
Query: 1 MEIVYVYVKKRSEFGKQCNFSDRQAELNIDIMPNPELAEQFVERNPVDTGIQCSISMSEH 60
MEIVYVYVKKRSEFGKQCNFSDRQAELNIDIMPNPELAEQFVERNPVDTGIQCSISMSEH
Sbjct: 1 MEIVYVYVKKRSEFGKQCNFSDRQAELNIDIMPNPELAEQFVERNPVDTGIQCSISMSEH 60
Query: 61 EANSERFEMETRGVNHVEGGWPKDVNPLELEQTIRFRKKVEKDENYVNAIMQLGSIMEHC 120
EANSERFEMETRGVNHVEGGWPKDVNPLELEQTIRFRKKVEKDENYVNAIMQLGSIMEHC
Sbjct: 61 EANSERFEMETRGVNHVEGGWPKDVNPLELEQTIRFRKKVEKDENYVNAIMQLGSIMEHC 120
Query: 121 IKQNNAIDIYEEYFNDEEAMEVMEEDPSAKTINVFRDPQEIKRAATHLSWHPDGNRKLAV 180
IKQNNAIDIYEEYFNDEEAMEVMEEDPSAKTINVFRDPQEIKRAATHLSWHPDGNRKLAV
Sbjct: 121 IKQNNAIDIYEEYFNDEEAMEVMEEDPSAKTINVFRDPQEIKRAATHLSWHPDGNRKLAV 180
Query: 181 AYSCLDFQRAPVGMSSDSYIWDLENPNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQ 240
AYSCLDFQRAPVGMSSDSYIWDLENPNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQ
Sbjct: 181 AYSCLDFQRAPVGMSSDSYIWDLENPNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQ 240
Query: 241 IACWDTRKGSLVAELSTIESSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEP 300
IACWDTRKGSLVAELSTIESSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEP
Sbjct: 241 IACWDTRKGSLVAELSTIESSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEP 300
Query: 301 TEVVILDITKKEQLENALGAISLEFESTLPTKFMVGTEQGIVISCNRKAKTSAEKIVCTF 360
TEVVILDITKKEQLENALGAISLEFESTLPTKFMVGTEQGIVISCNRKAKTSAEKIVCTF
Sbjct: 301 TEVVILDITKKEQLENALGAISLEFESTLPTKFMVGTEQGIVISCNRKAKTSAEKIVCTF 360
Query: 361 PGHHGPIYALQRNPFYPKNFLTVGDWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRP 420
PGHHGPIYALQRNPFYPKNFLTVGDWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRP
Sbjct: 361 PGHHGPIYALQRNPFYPKNFLTVGDWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRP 420
Query: 421 TVFFTTRMDGTLDIWDFMFEQCDPTLSLKVCDEALFCLRVQDNGCLIACGSQLGTTTLLE 480
TVFFTTRMDGTLDIWDFMFEQCDPTLSLKVCDEALFCLRVQDNGCLIACGSQLGTTTLLE
Sbjct: 421 TVFFTTRMDGTLDIWDFMFEQCDPTLSLKVCDEALFCLRVQDNGCLIACGSQLGTTTLLE 480
Query: 481 VSPGLSTLQRNEKNVASSMFERETRREKILEARHREMRLKEKGKAEGRDEEQTDEELAVD 540
VSPGLSTLQRNEKNVASSMFERETRREKILEARHREMRLKEKGKAEGRDEEQTDEELAVD
Sbjct: 481 VSPGLSTLQRNEKNVASSMFERETRREKILEARHREMRLKEKGKAEGRDEEQTDEELAVD 540
Query: 541 LEALVSKAEEEFFDIIFAELKKKEADAIKLTPVPQQPSPEEDQVVEEGEEAAGEEGDEEV 600
LEALVSKAEEEFFDIIFAELKKKEADAIKLTPVPQQPSPEEDQVVEEGEEAAGEEGDEEV
Sbjct: 541 LEALVSKAEEEFFDIIFAELKKKEADAIKLTPVPQQPSPEEDQVVEEGEEAAGEEGDEEV 600
Query: 601 EEDLA 605
EEDLA
Sbjct: 601 EEDLA 605
>gi|6912338 dynein, axonemal, intermediate chain 1 [Homo sapiens]
Length = 699
Score = 128 bits (321), Expect = 2e-29
Identities = 116/505 (22%), Positives = 216/505 (42%), Gaps = 39/505 (7%)
Query: 10 KRSEFGKQCNFSDRQAELNIDIMPNPELAEQFVERNPVDTGIQCSISMSE-HEANSERFE 68
K + Q NFS+R ++ NP + P T + + E ++A E E
Sbjct: 184 KERKLTNQFNFSERASQT----YNNPVRDRECQTEPPPRTNFSATANQWEIYDAYVEELE 239
Query: 69 METRGVNHVEGGWPKDVNPLELEQTIRFRKKVEKDENYVNAIMQLGSIMEHCIKQNNAID 128
+ + + P V + +R +E + + + Q IME + QN D
Sbjct: 240 KQEKTKEKEKAKTP--VAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVNQNTYDD 297
Query: 129 IYEEY-FNDEEAMEVMEEDPSAKTINVFRDPQEIKRAATHLSWHPDGNRKLAVAYSCLDF 187
I +++ + D+ A E ++ + + F++ + + + T L W+P AV Y DF
Sbjct: 298 IAQDFKYYDDAADEYRDQVGTLLPLWKFQNDKAKRLSVTALCWNPKYRDLFAVGYGSYDF 357
Query: 188 QRAPVGMSSDSYIWDLENPNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTR 247
+ GM ++ L+NP+ PE +S ++ L+ + +++ G Y+G +A ++ +
Sbjct: 358 MKQSRGML---LLYSLKNPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLK 414
Query: 248 KGSLVAEL--STIESSHRDPVYGTIWLQS--KTGTECFSASTDGQVMWWDIRKMSEPTEV 303
K S H DPV+ W + FS S+DG+++ W + K ++
Sbjct: 415 KPHSQPSFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVK----RKL 470
Query: 304 VILDITKKE------------QLENALGAISLEFESTLPTKFMVGTEQGIVISCNRKAKT 351
V +D+ K + QL + +F + F+VGTE+G + C +K+
Sbjct: 471 VHIDVIKLKVEGSTTEVPEGLQLHPVGCGTAFDFHKEIDYMFLVGTEEGKIYKC---SKS 527
Query: 352 SAEKIVCTFPGHHGPIYALQRNPFYPKNFLTV-GDWTARIWSEDSRESSIMWTKYHMAYL 410
+ + + T+ H+ + + NP++ K F++ DWT +IW D + M+ + +
Sbjct: 528 YSSQFLDTYDAHNMSVDTVSWNPYHTKVFMSCSSDWTVKIW--DHTIKTPMFIYDLNSAV 585
Query: 411 TDAAWSPVRPTVFFTTRMDGTLDIWDFMFEQCDPTLSLKVCDEALFCLRVQDN--GCLIA 468
D AW+P TVF DG I+D + + + V + VQ N +I
Sbjct: 586 GDVAWAPYSSTVFAAVTTDGKAHIFDLAINKYEAICNQPVAAKKNRLTHVQFNLIHPIII 645
Query: 469 CGSQLGTTTLLEVSPGLSTLQRNEK 493
G G L++SP L + + +K
Sbjct: 646 VGDDRGHIISLKLSPNLRKMPKEKK 670
>gi|66267730 WD repeat domain 34 [Homo sapiens]
Length = 536
Score = 110 bits (276), Expect = 3e-24
Identities = 92/352 (26%), Positives = 157/352 (44%), Gaps = 38/352 (10%)
Query: 166 THLSWHPDGNRKLAVAYSCLDFQRAPVGMSSDSYIWDLEN----PNKPELALKPSSPLVT 221
T +SW+ G+ +A AY LD + S W+L+ P +P ++ S ++
Sbjct: 165 TSISWNSTGS-VVACAYGRLDHGDWST-LKSFVCAWNLDRRDLRPQQPSAVVEVPSAVLC 222
Query: 222 LEFNPKDSHVLLGGCYNGQIACWDTRK--GSLVAELSTIESSHRDPVYGTIWLQSKTGTE 279
L F+P + GG Y+G++ WD + L+ + +H DPV +WL +
Sbjct: 223 LAFHPTQPSHVAGGLYSGEVLVWDLSRLEDPLLWRTGLTDDTHTDPVSQVVWLPEPGHSH 282
Query: 280 CF---SASTDGQVMWWD-----IRKMSEPTEVVILDITKKEQL------ENALGAISLEF 325
F S +TDG+V+ W +++E +V+ + + +L E +GA ++ F
Sbjct: 283 RFQVLSVATDGKVLLWQGIGVGQLQLTEGFALVMQQLPRSTKLKKHPRGETEVGATAVAF 342
Query: 326 ESTLPTKFMVGTEQGIVISCNRKAKTSA-----------EKIVCTFPGHHGPIYALQRNP 374
S P F++GTE G + C+ A +A TF H GPIY++ +P
Sbjct: 343 SSFDPRLFILGTEGGFPLKCSLAAGEAALTRMPSSVPLRAPAQFTFSPHGGPIYSVSCSP 402
Query: 375 FYPKNFLTVG-DWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRMDGTLD 433
F+ FL+ G D ++S + + + + YL WSPVRP VF G +
Sbjct: 403 FHRNLFLSAGTDGHVHLYSM-LQAPPLTSLQLSLKYLFAVRWSPVRPLVFAAASGKGDVQ 461
Query: 434 IWDFMFEQCDPTLSLKVC--DEALFCLRVQDNGC-LIACGSQLGTTTLLEVS 482
++D PT+ +K + ++CL L+A G GT + ++S
Sbjct: 462 LFDLQKSSQKPTVLIKQTQDESPVYCLEFNSQQTQLLAAGDAQGTVKVWQLS 513
>gi|217272887 WD repeat domain 63 [Homo sapiens]
Length = 891
Score = 108 bits (269), Expect = 2e-23
Identities = 76/233 (32%), Positives = 106/233 (45%), Gaps = 20/233 (8%)
Query: 331 TKFMVGTEQGIVISCNRKAKTSAE-------KIVCTFPGHHGPIYALQRNPFYPKNFLTV 383
TKF VGTE+G VI + K + E K V H G ++ +QR+PFY LTV
Sbjct: 632 TKFFVGTEEGEVIYTDWKMEKDPETGRLMSKKPVSHHTIHDGTVHTIQRSPFYNDIILTV 691
Query: 384 GDWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRMDGTLDIWDFMFEQCD 443
G W IW E ++ + T WS RP VF+ R DG +DIWD + + +
Sbjct: 692 GGWNVAIWKEGVMTGPLLQSCCAPKRYTSGHWSLTRPGVFYIGREDGYIDIWDLLEKTHE 751
Query: 444 PTLSLKVCDEALFCLR---VQDNGCLIACGSQLGTTTLLEVSPGLSTLQRNEKNVASSMF 500
P S +C + ++ IA GT +LE+ LS NE + F
Sbjct: 752 PAQSQNICITMITYIKPWIFSSKQQFIATADYYGTLHILEIPWTLSRPSTNEMASVNHYF 811
Query: 501 ERETR-------REKILEARHREMRL---KEKGKAEGRDEEQTDEELAVDLEA 543
ERE + R+KI E +EM L K+K K + +EQ EL +D E+
Sbjct: 812 EREVKHLEYVEQRKKIREQEKKEMELEMAKKKVKTYQKSKEQMQAELKMDYES 864
Score = 67.4 bits (163), Expect = 4e-11
Identities = 84/400 (21%), Positives = 155/400 (38%), Gaps = 91/400 (22%)
Query: 2 EIVYVYVKKRSEFGKQCNFSDRQAE------LNIDIMPNPELAEQFVERNPVDTGIQCSI 55
+I Y+ +KRSEFG FSD+ A + P+ + +E+ D G+Q
Sbjct: 180 QITYMISRKRSEFGAPIKFSDQNASSVKDAYIECTAYPDKNFTLKQLEK---DVGMQVIP 236
Query: 56 SMSEHEANSERFEMETRGVNHVEGGWPKDVNPLELEQTIRFRKKVEKDENYVNAIMQLGS 115
+ + ++ T N +P++ + E E +++ + V+ +
Sbjct: 237 QIKDISTQTKW----TYPKNATTQYYPREFSEEEKET-------LKQSKPLVDFLNNASI 285
Query: 116 IMEHCIKQNNAIDIYEE---YFNDEEAMEVMEEDPSAKTINVFRDPQE-IKRAATHLSWH 171
+E ++QN ++ + + Y +EE + D K F D ++ T +SWH
Sbjct: 286 SVEIALQQNEIMNTFIDDWKYLAEEEGTFGDKTDTHLKEYQSFTDLHSPTEKMITCVSWH 345
Query: 172 PDGNRKLAVAYSC-------LDFQRAPVGMSSDSYIWDLENPNKPELALKPSSPLVTLEF 224
P +AV+ + + F + S W +P P+L L+ + +F
Sbjct: 346 PTIYGLIAVSVAVRLSFEDRVHFSGKLLLQPSLILFWSFSDPIHPQLMLESPDDIFCFKF 405
Query: 225 NPKDSHVLLGGCYNGQIACWD---------------------TRKGSLVAE--------- 254
P D +++ GGC NGQI WD T K + E
Sbjct: 406 CPSDPNIIAGGCINGQIVMWDITAHADRIENIKAGGSRSKRATLKPMFLLEPESNKEAMY 465
Query: 255 -----LSTIESSHRDPVYGTIWL-------------QSKTGTEC--FSASTDGQVMWWDI 294
+S+IE+ H+ + WL ++++G C + S D + +WDI
Sbjct: 466 IRHCAVSSIENGHKKVITDIHWLSDTFEINRMGSVFENRSGICCQLVTCSADCTICFWDI 525
Query: 295 RKMSEPTEVVILDITKKEQLENALGAISLEFESTLPTKFM 334
R P + + T+K++ E S+E +P+ F+
Sbjct: 526 R----PQKPLTPQTTEKKKEE------SIEIPFDVPSTFL 555
>gi|24307879 dynein, cytoplasmic 1, intermediate chain 2 [Homo
sapiens]
Length = 638
Score = 103 bits (258), Expect = 3e-22
Identities = 97/416 (23%), Positives = 183/416 (43%), Gaps = 26/416 (6%)
Query: 91 EQTIRFRKKVEKDENYVNAIMQLGSIMEHCIKQNNAIDIYEEYFNDEEAMEVMEEDPSAK 150
E T ++++ E +++ I+E + + I+I+ +Y + + E AK
Sbjct: 207 ELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQ--INIFFDYSGRDLEDKEGEIQAGAK 264
Query: 151 -TIN--VFRDPQEIKRAATHLSWHPDGNRKLAVAYSCLDFQRAPVGMSSDSYIWDLE-NP 206
++N F + R + L W L +Y+ + + AP + +W+++
Sbjct: 265 LSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYN--NNEDAPHEPDGVALVWNMKYKK 322
Query: 207 NKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTR--KGSLVAELSTIESSHRD 264
PE S +++ F ++++GG Y+GQI WD R K + V ++H
Sbjct: 323 TTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTH 382
Query: 265 PVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEPTEVVILDITKKEQLENALGAISLE 324
PVY + ++ S STDG++ W + +S P + +++ K+ A+ S+
Sbjct: 383 PVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDS--MELVHKQS--KAVAVTSMS 438
Query: 325 FESTLPTKFMVGTEQGIVIS-CNRKAKTSAEKIVCTFPGHHGPIYALQRNPF-----YPK 378
F F+VG+E+G V + C +K ++ F GH GPI + + +
Sbjct: 439 FPVGDVNNFVVGSEEGSVYTACRHGSKAGISEM---FEGHQGPITGIHCHAAVGAVDFSH 495
Query: 379 NFLTVG-DWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRMDGTLDIWDF 437
F+T DWT ++W+ + + + + Y+ D WSP P +F G LD+W+
Sbjct: 496 LFVTSSFDWTVKLWTTKNNKPLYSFED-NADYVYDVMWSPTHPALFACVDGMGRLDLWNL 554
Query: 438 MFEQCDPTLSLKV-CDEALFCLRVQDNGCLIACGSQLGTTTLLEVSPGLSTLQRNE 492
+ PT S+ V + AL +R +G IA G G + +V ++ + +E
Sbjct: 555 NNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDE 610
>gi|46276887 WD repeat domain 78 isoform 1 [Homo sapiens]
Length = 848
Score = 102 bits (255), Expect = 8e-22
Identities = 80/303 (26%), Positives = 136/303 (44%), Gaps = 32/303 (10%)
Query: 168 LSWHPDGNRKLAVAYSCLDFQRAPVGMSSDSYIWDLENPNKPELALKPSSPLVTLEFNPK 227
L+W+ LAV Y F+ G++ W ++NP PE + + ++F+
Sbjct: 491 LAWNKTNPDLLAVGYGHFGFKEQKRGLAC---CWSIKNPMWPERIYQSPYGVTAVDFSIG 547
Query: 228 DSHVLLGGCYNGQIACWDTRKGSLVAELSTIES--SHRDPVYGTIWLQSKTGTE------ 279
++L G +NG IA ++ R S V L + ES H PV+ W++ GT
Sbjct: 548 APNLLAVGYHNGTIAIYNVRSNSNVPVLDSSESPQKHLGPVWQLQWIEQDRGTTGDGKRE 607
Query: 280 -CFSASTDGQVMWWDIRKMSEPTEVVILDIT---------KKEQLENAL-----GAISLE 324
S S DG++ W IRK + +++ L T +KE+ + AL +
Sbjct: 608 ILVSISADGRISKWVIRKGLDCYDLMRLKRTTAASNKKGGEKEKKDEALISRQAPGMCFA 667
Query: 325 FESTLPTKFMVGTEQGIVISCNRKAKTSAEKIVCTFPGHHGPIYALQRNPFYPKNFLTV- 383
F ++ GTE+G + C+ E+ + T+ GH GP+Y + NPF FL+
Sbjct: 668 FHPKDTNIYLAGTEEGHIHKCSCSYN---EQYLDTYRGHKGPVYKVTWNPFCHDVFLSCS 724
Query: 384 GDWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRMDGTLDIWDFMFEQCD 443
DW IW +++ + S+ + + + D AWSP + + F + ++IWD D
Sbjct: 725 ADWGVIIWQQENVKPSLSFYP-ATSVVYDVAWSP-KSSYIFAAANENRVEIWDLHISTLD 782
Query: 444 PTL 446
P +
Sbjct: 783 PLI 785
>gi|4758178 dynein, cytoplasmic 1, intermediate chain 1 isoform a
[Homo sapiens]
Length = 645
Score = 94.4 bits (233), Expect = 3e-19
Identities = 104/488 (21%), Positives = 201/488 (41%), Gaps = 37/488 (7%)
Query: 12 SEFGKQCNFSDRQAELNIDIMPNPELAEQFVERNPVDTGIQCSISMSEHEANSERFEMET 71
SE G++ + +D +P ++ + P+ T Q + E + ++
Sbjct: 139 SELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATH-QSEEDEEDEEMVESKVGQDS 197
Query: 72 RGVNHVEGGWPKDVNPLELEQTIRFRKKVEKDENYVNAIMQLGSIMEHCIKQNNAIDIYE 131
N + K+ P EL T ++++ E ++ + ++E + +++ I
Sbjct: 198 ELENQDKKQEVKEAPPREL--TEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDI---- 251
Query: 132 EYFNDEEAMEVMEEDPSAKT------INVFRDPQEIK-RAATHLSWHPDGNRKLAVAYSC 184
F D E+ E+D + F D K R T + W + +Y+
Sbjct: 252 --FFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYN- 308
Query: 185 LDFQRAPVGMSSDSYIWDLE-NPNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIAC 243
+ + AP + +W+++ PE S ++++ F ++++GG Y+GQI
Sbjct: 309 -NNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVL 367
Query: 244 WDTR--KGSLVAELSTIESSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEPT 301
WD R + + V ++H PVY + ++ + STDG++ W + +S P
Sbjct: 368 WDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQ 427
Query: 302 EVVILDITKKEQLENALGAISLEFESTLPTKFMVGTEQGIVIS-CNRKAKTSAEKIVCTF 360
E + L K + + + F + F+VG+E+G V + C +K ++ F
Sbjct: 428 ESMELVYNKSKPV----AVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEV---F 480
Query: 361 PGHHGPIYALQRNPF-----YPKNFLTVG-DWTARIWSEDSRESSIMWTKYHMAYLTDAA 414
GH GP+ + + + F+T DWT ++W+ + + + Y+ D
Sbjct: 481 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFED-NADYVYDVM 539
Query: 415 WSPVRPTVFFTTRMDGTLDIWDFMFEQCDPTLSLKV-CDEALFCLRVQDNGCLIACGSQL 473
WSPV P +F G LD+W+ + PT S+ + AL +R G +A G
Sbjct: 540 WSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSE 599
Query: 474 GTTTLLEV 481
G + +V
Sbjct: 600 GRIWVYDV 607
>gi|207113122 dynein, cytoplasmic 1, intermediate chain 1 isoform b
[Homo sapiens]
Length = 628
Score = 94.4 bits (233), Expect = 3e-19
Identities = 104/488 (21%), Positives = 201/488 (41%), Gaps = 37/488 (7%)
Query: 12 SEFGKQCNFSDRQAELNIDIMPNPELAEQFVERNPVDTGIQCSISMSEHEANSERFEMET 71
SE G++ + +D +P ++ + P+ T Q + E + ++
Sbjct: 122 SELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATH-QSEEDEEDEEMVESKVGQDS 180
Query: 72 RGVNHVEGGWPKDVNPLELEQTIRFRKKVEKDENYVNAIMQLGSIMEHCIKQNNAIDIYE 131
N + K+ P EL T ++++ E ++ + ++E + +++ I
Sbjct: 181 ELENQDKKQEVKEAPPREL--TEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDI---- 234
Query: 132 EYFNDEEAMEVMEEDPSAKT------INVFRDPQEIK-RAATHLSWHPDGNRKLAVAYSC 184
F D E+ E+D + F D K R T + W + +Y+
Sbjct: 235 --FFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYN- 291
Query: 185 LDFQRAPVGMSSDSYIWDLE-NPNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIAC 243
+ + AP + +W+++ PE S ++++ F ++++GG Y+GQI
Sbjct: 292 -NNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVL 350
Query: 244 WDTR--KGSLVAELSTIESSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEPT 301
WD R + + V ++H PVY + ++ + STDG++ W + +S P
Sbjct: 351 WDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQ 410
Query: 302 EVVILDITKKEQLENALGAISLEFESTLPTKFMVGTEQGIVIS-CNRKAKTSAEKIVCTF 360
E + L K + + + F + F+VG+E+G V + C +K ++ F
Sbjct: 411 ESMELVYNKSKPV----AVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEV---F 463
Query: 361 PGHHGPIYALQRNPF-----YPKNFLTVG-DWTARIWSEDSRESSIMWTKYHMAYLTDAA 414
GH GP+ + + + F+T DWT ++W+ + + + Y+ D
Sbjct: 464 EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFED-NADYVYDVM 522
Query: 415 WSPVRPTVFFTTRMDGTLDIWDFMFEQCDPTLSLKV-CDEALFCLRVQDNGCLIACGSQL 473
WSPV P +F G LD+W+ + PT S+ + AL +R G +A G
Sbjct: 523 WSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSE 582
Query: 474 GTTTLLEV 481
G + +V
Sbjct: 583 GRIWVYDV 590
>gi|207113124 dynein, cytoplasmic 1, intermediate chain 1 isoform c
[Homo sapiens]
Length = 608
Score = 92.8 bits (229), Expect = 8e-19
Identities = 78/330 (23%), Positives = 144/330 (43%), Gaps = 21/330 (6%)
Query: 163 RAATHLSWHPDGNRKLAVAYSCLDFQRAPVGMSSDSYIWDLE-NPNKPELALKPSSPLVT 221
R T + W + +Y+ + + AP + +W+++ PE S +++
Sbjct: 251 RVVTCMDWSLQYPELMVASYN--NNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMS 308
Query: 222 LEFNPKDSHVLLGGCYNGQIACWDTR--KGSLVAELSTIESSHRDPVYGTIWLQSKTGTE 279
+ F ++++GG Y+GQI WD R + + V ++H PVY + ++
Sbjct: 309 VCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHN 368
Query: 280 CFSASTDGQVMWWDIRKMSEPTEVVILDITKKEQLENALGAISLEFESTLPTKFMVGTEQ 339
+ STDG++ W + +S P E + L K + + + F + F+VG+E+
Sbjct: 369 LITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPV----AVTGMAFPTGDVNNFVVGSEE 424
Query: 340 GIVIS-CNRKAKTSAEKIVCTFPGHHGPIYALQRNPF-----YPKNFLTVG-DWTARIWS 392
G V + C +K ++ F GH GP+ + + + F+T DWT ++W+
Sbjct: 425 GTVYTACRHGSKAGIGEV---FEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWT 481
Query: 393 EDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRMDGTLDIWDFMFEQCDPTLSLKV-C 451
+ + + Y+ D WSPV P +F G LD+W+ + PT S+ +
Sbjct: 482 TKHNKPLYSFED-NADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG 540
Query: 452 DEALFCLRVQDNGCLIACGSQLGTTTLLEV 481
AL +R G +A G G + +V
Sbjct: 541 ASALNRVRWAQAGKEVAVGDSEGRIWVYDV 570
>gi|116256340 SEC31 homolog A isoform 3 [Homo sapiens]
Length = 1205
Score = 56.6 bits (135), Expect = 6e-08
Identities = 57/250 (22%), Positives = 90/250 (36%), Gaps = 67/250 (26%)
Query: 196 SDSYIWDLEN---PNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTRKGSLV 252
S+ YIWDL N P P +P + + +N + H+L +G+ WD RK +
Sbjct: 145 SEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDLRKNEPI 204
Query: 253 AELSTIESSHRDPVYGTIWLQSKTGTECFSASTDGQ---VMWWDIRKMSEPTEVVILDIT 309
++S + S+R G W T+ AS D + + WD+R S P V
Sbjct: 205 IKVS--DHSNRMHCSGLAW-HPDVATQMVLASEDDRLPVIQMWDLRFASSPLRV------ 255
Query: 310 KKEQLEN-ALGAISLEFESTLPTKFMVGTEQGIVISCNRKAKTSAEKIVCTFPGHHGPIY 368
LEN A G +++ + P +++SC + AK I+C+ P +Y
Sbjct: 256 ----LENHARGILAIAWSMADPE---------LLLSCGKDAK-----ILCSNPNTGEVLY 297
Query: 369 ALQRNPFYPKNFLTVGDWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRM 428
L N + D W P P V
Sbjct: 298 ELPTNT---------------------------------QWCFDIQWCPRNPAVLSAASF 324
Query: 429 DGTLDIWDFM 438
DG + ++ M
Sbjct: 325 DGRISVYSIM 334
>gi|116256338 SEC31 homolog A isoform 1 [Homo sapiens]
Length = 1220
Score = 56.6 bits (135), Expect = 6e-08
Identities = 57/250 (22%), Positives = 90/250 (36%), Gaps = 67/250 (26%)
Query: 196 SDSYIWDLEN---PNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTRKGSLV 252
S+ YIWDL N P P +P + + +N + H+L +G+ WD RK +
Sbjct: 145 SEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDLRKNEPI 204
Query: 253 AELSTIESSHRDPVYGTIWLQSKTGTECFSASTDGQ---VMWWDIRKMSEPTEVVILDIT 309
++S + S+R G W T+ AS D + + WD+R S P V
Sbjct: 205 IKVS--DHSNRMHCSGLAW-HPDVATQMVLASEDDRLPVIQMWDLRFASSPLRV------ 255
Query: 310 KKEQLEN-ALGAISLEFESTLPTKFMVGTEQGIVISCNRKAKTSAEKIVCTFPGHHGPIY 368
LEN A G +++ + P +++SC + AK I+C+ P +Y
Sbjct: 256 ----LENHARGILAIAWSMADPE---------LLLSCGKDAK-----ILCSNPNTGEVLY 297
Query: 369 ALQRNPFYPKNFLTVGDWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRM 428
L N + D W P P V
Sbjct: 298 ELPTNT---------------------------------QWCFDIQWCPRNPAVLSAASF 324
Query: 429 DGTLDIWDFM 438
DG + ++ M
Sbjct: 325 DGRISVYSIM 334
>gi|116256336 SEC31 homolog A isoform 4 [Homo sapiens]
Length = 1106
Score = 56.6 bits (135), Expect = 6e-08
Identities = 57/250 (22%), Positives = 90/250 (36%), Gaps = 67/250 (26%)
Query: 196 SDSYIWDLEN---PNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTRKGSLV 252
S+ YIWDL N P P +P + + +N + H+L +G+ WD RK +
Sbjct: 145 SEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDLRKNEPI 204
Query: 253 AELSTIESSHRDPVYGTIWLQSKTGTECFSASTDGQ---VMWWDIRKMSEPTEVVILDIT 309
++S + S+R G W T+ AS D + + WD+R S P V
Sbjct: 205 IKVS--DHSNRMHCSGLAW-HPDVATQMVLASEDDRLPVIQMWDLRFASSPLRV------ 255
Query: 310 KKEQLEN-ALGAISLEFESTLPTKFMVGTEQGIVISCNRKAKTSAEKIVCTFPGHHGPIY 368
LEN A G +++ + P +++SC + AK I+C+ P +Y
Sbjct: 256 ----LENHARGILAIAWSMADPE---------LLLSCGKDAK-----ILCSNPNTGEVLY 297
Query: 369 ALQRNPFYPKNFLTVGDWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRM 428
L N + D W P P V
Sbjct: 298 ELPTNT---------------------------------QWCFDIQWCPRNPAVLSAASF 324
Query: 429 DGTLDIWDFM 438
DG + ++ M
Sbjct: 325 DGRISVYSIM 334
>gi|41349441 SEC31 homolog A isoform 2 [Homo sapiens]
Length = 1181
Score = 56.6 bits (135), Expect = 6e-08
Identities = 57/250 (22%), Positives = 90/250 (36%), Gaps = 67/250 (26%)
Query: 196 SDSYIWDLEN---PNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTRKGSLV 252
S+ YIWDL N P P +P + + +N + H+L +G+ WD RK +
Sbjct: 145 SEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDLRKNEPI 204
Query: 253 AELSTIESSHRDPVYGTIWLQSKTGTECFSASTDGQ---VMWWDIRKMSEPTEVVILDIT 309
++S + S+R G W T+ AS D + + WD+R S P V
Sbjct: 205 IKVS--DHSNRMHCSGLAW-HPDVATQMVLASEDDRLPVIQMWDLRFASSPLRV------ 255
Query: 310 KKEQLEN-ALGAISLEFESTLPTKFMVGTEQGIVISCNRKAKTSAEKIVCTFPGHHGPIY 368
LEN A G +++ + P +++SC + AK I+C+ P +Y
Sbjct: 256 ----LENHARGILAIAWSMADPE---------LLLSCGKDAK-----ILCSNPNTGEVLY 297
Query: 369 ALQRNPFYPKNFLTVGDWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRM 428
L N + D W P P V
Sbjct: 298 ELPTNT---------------------------------QWCFDIQWCPRNPAVLSAASF 324
Query: 429 DGTLDIWDFM 438
DG + ++ M
Sbjct: 325 DGRISVYSIM 334
>gi|41349439 SEC31 homolog A isoform 1 [Homo sapiens]
Length = 1220
Score = 56.6 bits (135), Expect = 6e-08
Identities = 57/250 (22%), Positives = 90/250 (36%), Gaps = 67/250 (26%)
Query: 196 SDSYIWDLEN---PNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTRKGSLV 252
S+ YIWDL N P P +P + + +N + H+L +G+ WD RK +
Sbjct: 145 SEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDLRKNEPI 204
Query: 253 AELSTIESSHRDPVYGTIWLQSKTGTECFSASTDGQ---VMWWDIRKMSEPTEVVILDIT 309
++S + S+R G W T+ AS D + + WD+R S P V
Sbjct: 205 IKVS--DHSNRMHCSGLAW-HPDVATQMVLASEDDRLPVIQMWDLRFASSPLRV------ 255
Query: 310 KKEQLEN-ALGAISLEFESTLPTKFMVGTEQGIVISCNRKAKTSAEKIVCTFPGHHGPIY 368
LEN A G +++ + P +++SC + AK I+C+ P +Y
Sbjct: 256 ----LENHARGILAIAWSMADPE---------LLLSCGKDAK-----ILCSNPNTGEVLY 297
Query: 369 ALQRNPFYPKNFLTVGDWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRM 428
L N + D W P P V
Sbjct: 298 ELPTNT---------------------------------QWCFDIQWCPRNPAVLSAASF 324
Query: 429 DGTLDIWDFM 438
DG + ++ M
Sbjct: 325 DGRISVYSIM 334
>gi|14149696 SEC31 homolog B [Homo sapiens]
Length = 1179
Score = 47.4 bits (111), Expect = 4e-05
Identities = 32/116 (27%), Positives = 53/116 (45%), Gaps = 10/116 (8%)
Query: 196 SDSYIWDLENPNKP----ELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTRKGSL 251
S+ +IWDL N N P + +P + L +N + H+L +G+ WD RK
Sbjct: 144 SEIFIWDLNNLNVPMTLGSKSQQPPEDIKALSWNRQAQHILSSAHPSGKAVVWDLRKNEP 203
Query: 252 VAELSTIESSHRDPVYGTIWLQSKTGTECFSASTDGQ---VMWWDIRKMSEPTEVV 304
+ ++S + S+R G W T+ S D + + WD+R S P +V+
Sbjct: 204 IIKVS--DHSNRMHCSGLAW-HPDIATQLVLCSEDDRLPVIQLWDLRFASSPLKVL 256
Score = 34.3 bits (77), Expect = 0.34
Identities = 44/239 (18%), Positives = 90/239 (37%), Gaps = 13/239 (5%)
Query: 203 LENPNKPELALKP--SSPLVTLEFNPKDSHVLLGGCYNGQIACWDTRKGSLVAELSTIES 260
L + +P +A K + + L+ NP ++L G + +I WD ++ L +
Sbjct: 106 LSSGKEPVIAQKQKHTGAVRALDLNPFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQ 165
Query: 261 SHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEPTEVVILDITKKEQLENALGA 320
+ + W + SA G+ + WD+RK +EP I K N +
Sbjct: 166 QPPEDIKALSW-NRQAQHILSSAHPSGKAVVWDLRK-NEP-------IIKVSDHSNRMHC 216
Query: 321 ISLEFESTLPTKFMVGTEQGIVISCNRKAKTSAEKIVCTFPGHHGPIYALQRNPFYPKNF 380
L + + T+ ++ +E + A + H I ++ + +
Sbjct: 217 SGLAWHPDIATQLVLCSEDDRLPVIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELL 276
Query: 381 LTVGDWTARIWSEDSRESSIMW-TKYHMAYLTDAAWSPVRPTVFFTTRMDGTLDIWDFM 438
LT ++I + S +++ ++ D W P P+VF +G + ++ M
Sbjct: 277 LTSAK-DSQILCRNLGSSEVVYKLPTQSSWCFDVQWCPRDPSVFSAASFNGWISLYSVM 334
>gi|58331266 WD repeat domain 59 [Homo sapiens]
Length = 974
Score = 47.4 bits (111), Expect = 4e-05
Identities = 27/98 (27%), Positives = 50/98 (51%), Gaps = 5/98 (5%)
Query: 199 YIWDLENPNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTRKGSLVAELSTI 258
YIWD+++ KP +AL + +++N K+++ L ++G + WD RK S E
Sbjct: 131 YIWDIKDTRKPTVALSAVAGASQVKWNKKNAN-CLATSHDGDVRIWDKRKPSTAVEYL-- 187
Query: 259 ESSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRK 296
++H ++G W + ++S D V +WD R+
Sbjct: 188 -AAHLSKIHGLDW-HPDSEHILATSSQDNSVKFWDYRQ 223
Score = 31.6 bits (70), Expect = 2.2
Identities = 12/56 (21%), Positives = 25/56 (44%)
Query: 382 TVGDWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRMDGTLDIWDF 437
T D RIW + +++ + H++ + W P + T+ D ++ WD+
Sbjct: 166 TSHDGDVRIWDKRKPSTAVEYLAAHLSKIHGLDWHPDSEHILATSSQDNSVKFWDY 221
>gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens]
Length = 323
Score = 47.0 bits (110), Expect = 5e-05
Identities = 41/174 (23%), Positives = 68/174 (39%), Gaps = 15/174 (8%)
Query: 264 DPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEPTEVVILDITKKEQLENALGAISL 323
D ++ W ++ + S DG + WD K + P +V E+A S+
Sbjct: 68 DGLFDVTWSENNEHV-LITCSGDGSLQLWDTAKAAGPLQVY---------KEHAQEVYSV 117
Query: 324 EFESTLPTKFMVGTEQGIVISCNRKAKTSAEKIVCTFPGHHGPIYALQRNPFYPKNFLTV 383
++ T + +V + + + K +CTF GH IY+ +P P F +
Sbjct: 118 DWSQTRGEQLVVSGSWDQTV---KLWDPTVGKSLCTFRGHESIIYSTIWSPHIPGCFASA 174
Query: 384 -GDWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRMDGTLDIWD 436
GD T RIW + I+ H A + W + T +D +L WD
Sbjct: 175 SGDQTLRIWDVKAAGVRIV-IPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWD 227
Score = 37.7 bits (86), Expect = 0.031
Identities = 49/255 (19%), Positives = 88/255 (34%), Gaps = 46/255 (18%)
Query: 219 LVTLEFNPKDSHVLLGGCYNGQIACWDTRKGSLVAELSTIESSHRDPVYGTIWLQSKTGT 278
L + ++ + HVL+ +G + WDT K + + + H VY W Q++
Sbjct: 70 LFDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQ---VYKEHAQEVYSVDWSQTRGEQ 126
Query: 279 ECFSASTDGQVMWWDIRKMSEPT-----------EVVILDITKKEQLENALGAIS----- 322
S S D V WD PT E +I + + S
Sbjct: 127 LVVSGSWDQTVKLWD------PTVGKSLCTFRGHESIIYSTIWSPHIPGCFASASGDQTL 180
Query: 323 -LEFESTLPTKFMVGTEQGIVISCN----RKAKTSAEKIVCTFPGHH------------G 365
+ + ++ Q ++SC+ + + C+ G G
Sbjct: 181 RIWDVKAAGVRIVIPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQPVFELLG 240
Query: 366 PIYALQRNPFYPKNFLTVG----DWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRPT 421
YA++R F P + + D+T R W+ +S + ++H + +S PT
Sbjct: 241 HTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDSLLETVEHHTEFTCGLDFSLQSPT 300
Query: 422 VFFTTRMDGTLDIWD 436
D T+ I+D
Sbjct: 301 QVADCSWDETIKIYD 315
Score = 30.0 bits (66), Expect = 6.4
Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 10/84 (11%)
Query: 361 PGHHGPIYALQRNPFYP--------KNFLTVGDWTARIWSEDSRESSIMWTKYHMAYLTD 412
PG HG YA + +P+ P +++ G T I D + + L D
Sbjct: 15 PGRHG--YAAEFSPYLPGRLACATAQHYGIAGCGTLLILDPDEAGLRLFRSFDWNDGLFD 72
Query: 413 AAWSPVRPTVFFTTRMDGTLDIWD 436
WS V T DG+L +WD
Sbjct: 73 VTWSENNEHVLITCSGDGSLQLWD 96
>gi|62234461 Notchless gene homolog isoform a [Homo sapiens]
Length = 485
Score = 44.7 bits (104), Expect = 3e-04
Identities = 38/151 (25%), Positives = 60/151 (39%), Gaps = 11/151 (7%)
Query: 150 KTINVFRDPQEI--KRAATHLSWHPDGNRKLAVAYSCLDFQRAPVGMSSDSYI--WDLEN 205
K +++ PQ I RA T + +G+ + ++ + + S D+ + WDL
Sbjct: 86 KVLDIIYQPQAIFRVRAVTRCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLST 145
Query: 206 PNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTRKGSLVAELSTIESSHRDP 265
++++ ++P D L GC NGQI WD G V + H
Sbjct: 146 ETPHFTCKGHRHWVLSISWSP-DGRKLASGCKNGQILLWDPSTGKQVGRTL---AGHSKW 201
Query: 266 VYGTIWLQSKTGTEC---FSASTDGQVMWWD 293
+ G W EC S+S DG V WD
Sbjct: 202 ITGLSWEPLHANPECRYVASSSKDGSVRIWD 232
Score = 36.2 bits (82), Expect = 0.089
Identities = 23/97 (23%), Positives = 36/97 (37%), Gaps = 6/97 (6%)
Query: 199 YIWDLENPNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTRKGSLVAELSTI 258
++W KP + L+ DS ++ ++ I WD R G +A L
Sbjct: 354 FLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASL--- 410
Query: 259 ESSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIR 295
H VY W S S S+D + WD++
Sbjct: 411 -RGHVAAVYQIAW--SADSRLLVSGSSDSTLKVWDVK 444
>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
sapiens]
Length = 390
Score = 44.3 bits (103), Expect = 3e-04
Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 7/103 (6%)
Query: 200 IWDLE--NPNKPELALKPSSPLVT-LEFNPKDSHVLLGGCYNGQIACWDTRKGSLVAELS 256
IWD N +KP ++ + V L FNP +L G + +A WD R +L +L
Sbjct: 219 IWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLR--NLKLKLH 276
Query: 257 TIESSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSE 299
+ E SH+D ++ W T S+ TD ++ WD+ K+ E
Sbjct: 277 SFE-SHKDEIFQVQW-SPHNETILASSGTDRRLNVWDLSKIGE 317
Score = 39.3 bits (90), Expect = 0.011
Identities = 42/180 (23%), Positives = 73/180 (40%), Gaps = 14/180 (7%)
Query: 262 HRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEPTEVVILDITKKEQLENALGAI 321
H+ YG W + +G SAS D + WDI + + +VV + + A+
Sbjct: 141 HQKEGYGLSWNPNLSG-HLLSASDDHTICLWDISAVPKEGKVV-----DAKTIFTGHTAV 194
Query: 322 SLEFESTLPTKFMVGT---EQGIVISCNRKAKTSAEKIVCTFPGHHGPIYALQRNPFYPK 378
+ L + + G+ +Q ++I R TS K + H + L NP Y +
Sbjct: 195 VEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTS--KPSHSVDAHTAEVNCLSFNP-YSE 251
Query: 379 NFLTVG--DWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRMDGTLDIWD 436
L G D T +W + + + + H + WSP T+ ++ D L++WD
Sbjct: 252 FILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWD 311
>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
sapiens]
Length = 424
Score = 44.3 bits (103), Expect = 3e-04
Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 7/103 (6%)
Query: 200 IWDLE--NPNKPELALKPSSPLVT-LEFNPKDSHVLLGGCYNGQIACWDTRKGSLVAELS 256
IWD N +KP ++ + V L FNP +L G + +A WD R +L +L
Sbjct: 253 IWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLR--NLKLKLH 310
Query: 257 TIESSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSE 299
+ E SH+D ++ W T S+ TD ++ WD+ K+ E
Sbjct: 311 SFE-SHKDEIFQVQW-SPHNETILASSGTDRRLNVWDLSKIGE 351
Score = 39.3 bits (90), Expect = 0.011
Identities = 42/180 (23%), Positives = 73/180 (40%), Gaps = 14/180 (7%)
Query: 262 HRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEPTEVVILDITKKEQLENALGAI 321
H+ YG W + +G SAS D + WDI + + +VV + + A+
Sbjct: 175 HQKEGYGLSWNPNLSG-HLLSASDDHTICLWDISAVPKEGKVV-----DAKTIFTGHTAV 228
Query: 322 SLEFESTLPTKFMVGT---EQGIVISCNRKAKTSAEKIVCTFPGHHGPIYALQRNPFYPK 378
+ L + + G+ +Q ++I R TS K + H + L NP Y +
Sbjct: 229 VEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTS--KPSHSVDAHTAEVNCLSFNP-YSE 285
Query: 379 NFLTVG--DWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRMDGTLDIWD 436
L G D T +W + + + + H + WSP T+ ++ D L++WD
Sbjct: 286 FILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWD 345
>gi|5032027 retinoblastoma binding protein 4 isoform a [Homo
sapiens]
Length = 425
Score = 44.3 bits (103), Expect = 3e-04
Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 7/103 (6%)
Query: 200 IWDLE--NPNKPELALKPSSPLVT-LEFNPKDSHVLLGGCYNGQIACWDTRKGSLVAELS 256
IWD N +KP ++ + V L FNP +L G + +A WD R +L +L
Sbjct: 254 IWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLR--NLKLKLH 311
Query: 257 TIESSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSE 299
+ E SH+D ++ W T S+ TD ++ WD+ K+ E
Sbjct: 312 SFE-SHKDEIFQVQW-SPHNETILASSGTDRRLNVWDLSKIGE 352
Score = 39.3 bits (90), Expect = 0.011
Identities = 42/180 (23%), Positives = 73/180 (40%), Gaps = 14/180 (7%)
Query: 262 HRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEPTEVVILDITKKEQLENALGAI 321
H+ YG W + +G SAS D + WDI + + +VV + + A+
Sbjct: 176 HQKEGYGLSWNPNLSG-HLLSASDDHTICLWDISAVPKEGKVV-----DAKTIFTGHTAV 229
Query: 322 SLEFESTLPTKFMVGT---EQGIVISCNRKAKTSAEKIVCTFPGHHGPIYALQRNPFYPK 378
+ L + + G+ +Q ++I R TS K + H + L NP Y +
Sbjct: 230 VEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTS--KPSHSVDAHTAEVNCLSFNP-YSE 286
Query: 379 NFLTVG--DWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRMDGTLDIWD 436
L G D T +W + + + + H + WSP T+ ++ D L++WD
Sbjct: 287 FILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWD 346
>gi|155030242 WD repeat domain 60 [Homo sapiens]
Length = 1066
Score = 44.3 bits (103), Expect = 3e-04
Identities = 34/144 (23%), Positives = 59/144 (40%), Gaps = 8/144 (5%)
Query: 321 ISLEFESTLPTKFMVGTEQGIVISCNRKAKTSAEKIVCTFPGHHG----PIYALQRNPFY 376
++++F + P F++GT+ G++ R+ A K+ P HG + + +PF
Sbjct: 864 LNVKFLPSDPNHFIIGTDMGLISHGTRQDLRVAPKLFK--PQQHGIRPVKVNVIDFSPFG 921
Query: 377 PKNFLT-VGDWTARIWSEDSRESSIMWTKYHMAY-LTDAAWSPVRPTVFFTTRMDGTLDI 434
FL D + R+ S + W ++ +T WSP RP VF + I
Sbjct: 922 EPIFLAGCSDGSIRLHQLSSAFPLLQWDSSTDSHAVTGLQWSPTRPAVFLVQDDTSNIYI 981
Query: 435 WDFMFEQCDPTLSLKVCDEALFCL 458
WD + P +V L +
Sbjct: 982 WDLLQSDLGPVAKQQVSPNRLVAM 1005
>gi|188219762 denticleless homolog [Homo sapiens]
Length = 730
Score = 42.4 bits (98), Expect = 0.001
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 3/103 (2%)
Query: 335 VGTEQGIVISCNRKAKTSAEKIVCTFPGHHGPIYALQRNPFYPKNFLTVGDWTARIWSED 394
V E+G V N ++++ +K + H ++ L P K GD TA+ W D
Sbjct: 69 VANEEGFVRLYNTESQSFRKKCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFW--D 126
Query: 395 SRESSIMWT-KYHMAYLTDAAWSPVRPTVFFTTRMDGTLDIWD 436
+ ++ T K H L A+S VF T DG + +WD
Sbjct: 127 VKAGELIGTCKGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWD 169
Score = 42.4 bits (98), Expect = 0.001
Identities = 72/335 (21%), Positives = 107/335 (31%), Gaps = 51/335 (15%)
Query: 135 NDEEAMEVMEEDPSAKTINVFRDPQEIKRAATHLSWHPDGNRKLAVAYSCLDFQRAPVGM 194
N+E + + + + F++ A L+W P G KL A
Sbjct: 71 NEEGFVRLYNTESQSFRKKCFKEWMAHWNAVFDLAWVP-GELKLVTAAG----------- 118
Query: 195 SSDSYIWDLENPNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTR---KGSL 251
+ WD++ L ++ F+ + V G +G I WDTR K
Sbjct: 119 DQTAKFWDVKAGELIGTCKGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWDTRCNKKDGF 178
Query: 252 VAELSTIESSHRDPVYGT------------------------IWLQSKTGTECFSASTDG 287
+++ I +H T + L T + + DG
Sbjct: 179 YRQVNQISGAHNTSDKQTPSKPKKKQNSKGLAPSVDFQQSVTVVLFQDENTLVSAGAVDG 238
Query: 288 QVMWWDIRK-----MSEPTEVVILDITKKEQLENALGAISLEFESTLPTKFMVGTEQGIV 342
+ WD+RK EP + LG SL +ST T F T+ I
Sbjct: 239 IIKVWDLRKNYTAYRQEP--IASKSFLYPGSSTRKLGYSSLILDSTGSTLFANCTDDNIY 296
Query: 343 ISCNRKAKTSAEKIVCTFPGHHGPIYALQRNPFYPKNFLTVG--DWTARIWSEDSRESSI 400
+ KTS V F GH + ++ + FL G D A IW +
Sbjct: 297 MFNMTGLKTSP---VAIFNGHQNSTFYVKSSLSPDDQFLVSGSSDEAAYIWKVSTPWQPP 353
Query: 401 MWTKYHMAYLTDAAWSPVRPTVFFTTRMDGTLDIW 435
H +T W P T T D TL IW
Sbjct: 354 TVLLGHSQEVTSVCWCPSDFTKIATCSDDNTLKIW 388
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 42.4 bits (98), Expect = 0.001
Identities = 31/103 (30%), Positives = 44/103 (42%), Gaps = 7/103 (6%)
Query: 200 IWDLENPNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTRKGSLVAELSTIE 259
+WD+ N N + P+ +L F+P + L G +G++ WD G +V EL
Sbjct: 653 LWDVLNGNCVRIFTGHKGPIHSLTFSP-NGRFLATGATDGRVLLWDIGHGLMVGEL---- 707
Query: 260 SSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEPTE 302
H D V + S+ G S S D V WD K E E
Sbjct: 708 KGHTDTVCSLRF--SRDGEILASGSMDNTVRLWDAIKAFEDLE 748
Score = 34.3 bits (77), Expect = 0.34
Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 7/71 (9%)
Query: 224 FNPKDSHVLLGGCYNGQIACWDTRKGSLVAELSTIESSHRDPVYGTIWLQSKTGTECFSA 283
F+P ++V G + + WD G+ V I + H+ P++ + S G +
Sbjct: 635 FHPNSNYVATGSA-DRTVRLWDVLNGNCVR----IFTGHKGPIHSLTF--SPNGRFLATG 687
Query: 284 STDGQVMWWDI 294
+TDG+V+ WDI
Sbjct: 688 ATDGRVLLWDI 698
>gi|168229161 coronin 7 [Homo sapiens]
Length = 925
Score = 41.6 bits (96), Expect = 0.002
Identities = 35/146 (23%), Positives = 59/146 (40%), Gaps = 24/146 (16%)
Query: 164 AATHLSWHPDGNRKLAVAYSCLDFQRAPVGMSSDSYIWDLENPNKPELALKPSSPLV--- 220
A T L+W P +LAVA G + +W + E+ P + L
Sbjct: 546 AVTDLAWDPFDPHRLAVA-----------GEDARIRLWRVPAEGLEEVLTTPETVLTGHT 594
Query: 221 ----TLEFNPKDSHVLLGGCYNGQIACWDTRKGSLVAELSTIESSHRDPVYGTIWLQSKT 276
+L F+P ++VL Y+ + WD + G+ +L H+D ++ W S
Sbjct: 595 EKICSLRFHPLAANVLASSSYDLTVRIWDLQAGADRLKL----QGHQDQIFSLAW--SPD 648
Query: 277 GTECFSASTDGQVMWWDIRKMSEPTE 302
G + + DG+V + R EP +
Sbjct: 649 GQQLATVCKDGRVRVYRPRSGPEPLQ 674
>gi|53759148 retinoblastoma binding protein 5 [Homo sapiens]
Length = 538
Score = 41.6 bits (96), Expect = 0.002
Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 7/89 (7%)
Query: 206 PNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTRKGSLVAELSTIESSHRDP 265
P + + L S +T FN + +L GC +G+I WD L ++ I S+H P
Sbjct: 14 PEEADGTLDCISMALTCTFN-RWGTLLAVGCNDGRIVIWDF----LTRGIAKIISAHIHP 68
Query: 266 VYGTIWLQSKTGTECFSASTDGQVMWWDI 294
V W S+ G + SASTD V WD+
Sbjct: 69 VCSLCW--SRDGHKLVSASTDNIVSQWDV 95
>gi|8922301 WD repeat domain 70 [Homo sapiens]
Length = 654
Score = 41.2 bits (95), Expect = 0.003
Identities = 30/115 (26%), Positives = 46/115 (40%), Gaps = 27/115 (23%)
Query: 201 WDLENPNKPELALKPSSP-----LVTLEFNPKDSHVLLGGCYNGQIACWDTRKGSLVAEL 255
W++ENP K + KP + + T +D +++ C NG I WD L
Sbjct: 311 WEVENPKKQKSVFKPRTMQGKKVIPTTCTYSRDGNLIAAACQNGSIQIWD-------RNL 363
Query: 256 STIESSHRDPVYGTIWLQSKTGTECFSASTDGQVM----------WWDIRKMSEP 300
+ H + S T T C + S DG V+ WDIR+ ++P
Sbjct: 364 TVHPKFHYKQAH-----DSGTDTSCVTFSYDGNVLASRGGDDSLKLWDIRQFNKP 413
Score = 30.4 bits (67), Expect = 4.9
Identities = 27/121 (22%), Positives = 55/121 (45%), Gaps = 16/121 (13%)
Query: 486 STLQRNEKNVASSMFERETRREKILEARHREMR--------LKEKGKAEGRDEEQTDEEL 537
+ ++R+ K + + E E REK L ++ ++ +++ K+ RD ++ E
Sbjct: 49 TAVERSRKTLEAREKEEEMNREKELRRQNEDIEPTSSRSNVVRDCSKSSSRDTSSSESEQ 108
Query: 538 AVDLEALVSKAEEEFFDIIFAELKKKEADAIK---LTPVPQQPSPEEDQVVEEGEEAAGE 594
+ D S +E + ++ K + ++ L P+P + EE++ EE EE E
Sbjct: 109 SSD-----SSDDELIGPPLPPKMVGKPVNFMEEDILGPLPPPLNEEEEEAEEEEEEEEEE 163
Query: 595 E 595
E
Sbjct: 164 E 164
>gi|21541824 transducin-like enhancer protein 1 [Homo sapiens]
Length = 770
Score = 40.4 bits (93), Expect = 0.005
Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 9/106 (8%)
Query: 193 GMSSDSYIWDLENPN-KPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTRKGSL 251
G +S IWDL P + + L S+P DS V C +G IA WD +L
Sbjct: 549 GEASTLSIWDLAAPTPRIKAELTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTL 608
Query: 252 VAELSTIESSHRDPVYGTIWLQ-SKTGTECFSASTDGQVMWWDIRK 296
V + H D G + S GT+ ++ D V WD+R+
Sbjct: 609 VRQFQ----GHTD---GASCIDISNDGTKLWTGGLDNTVRSWDLRE 647
>gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens]
Length = 1298
Score = 40.4 bits (93), Expect = 0.005
Identities = 29/107 (27%), Positives = 48/107 (44%), Gaps = 5/107 (4%)
Query: 200 IWDLENPNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTRKGSLVAELSTIE 259
IWD + ++P+ L +N + ++L+ G ++ I WDTR+G+ V +
Sbjct: 569 IWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTV---- 624
Query: 260 SSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEPTEVVIL 306
H VYG S+ T S S D V W + + P ++ IL
Sbjct: 625 YDHGADVYGLTCHPSRPFTMA-SCSRDSTVRLWSLTALVTPVQINIL 670
Score = 38.1 bits (87), Expect = 0.024
Identities = 53/257 (20%), Positives = 96/257 (37%), Gaps = 38/257 (14%)
Query: 200 IWDLENPNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTRKGSLVAELST-- 257
+WD+ + + +L + P + + GG W+ +KG ++ +
Sbjct: 396 VWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHG 455
Query: 258 ------IESSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEPTEVVILDITKK 311
I SH+D I S G C + DG+V+ K P V D ++
Sbjct: 456 TNGIFCIAWSHKDSK--RIATCSSDGF-CIIRTIDGKVL----HKYKHPAAVFGCDWSQN 508
Query: 312 EQLENALGAISLEFESTLPTKFMVGTEQGIVISCNRKAKTSAEKIVCTFPGHHGPIYALQ 371
+ A G E T + V T S+++ + F GH ++ ++
Sbjct: 509 NKDMIATGC-----EDTNVRVYYVAT--------------SSDQPLKVFSGHTAKVFHVK 549
Query: 372 RNPFYPKNFLTVG--DWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRMD 429
+P + L G D T RIW + ++++ I H A + W+ P + + D
Sbjct: 550 WSPLR-EGILCSGSDDGTVRIW-DYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWD 607
Query: 430 GTLDIWDFMFEQCDPTL 446
T+ +WD C T+
Sbjct: 608 YTIKVWDTREGTCVDTV 624
>gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens]
Length = 1322
Score = 40.4 bits (93), Expect = 0.005
Identities = 29/107 (27%), Positives = 48/107 (44%), Gaps = 5/107 (4%)
Query: 200 IWDLENPNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTRKGSLVAELSTIE 259
IWD + ++P+ L +N + ++L+ G ++ I WDTR+G+ V +
Sbjct: 593 IWDYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTCVDTV---- 648
Query: 260 SSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEPTEVVIL 306
H VYG S+ T S S D V W + + P ++ IL
Sbjct: 649 YDHGADVYGLTCHPSRPFTMA-SCSRDSTVRLWSLTALVTPVQINIL 694
Score = 38.1 bits (87), Expect = 0.024
Identities = 53/257 (20%), Positives = 96/257 (37%), Gaps = 38/257 (14%)
Query: 200 IWDLENPNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQIACWDTRKGSLVAELST-- 257
+WD+ + + +L + P + + GG W+ +KG ++ +
Sbjct: 420 VWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHG 479
Query: 258 ------IESSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEPTEVVILDITKK 311
I SH+D I S G C + DG+V+ K P V D ++
Sbjct: 480 TNGIFCIAWSHKDSK--RIATCSSDGF-CIIRTIDGKVL----HKYKHPAAVFGCDWSQN 532
Query: 312 EQLENALGAISLEFESTLPTKFMVGTEQGIVISCNRKAKTSAEKIVCTFPGHHGPIYALQ 371
+ A G E T + V T S+++ + F GH ++ ++
Sbjct: 533 NKDMIATGC-----EDTNVRVYYVAT--------------SSDQPLKVFSGHTAKVFHVK 573
Query: 372 RNPFYPKNFLTVG--DWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRMD 429
+P + L G D T RIW + ++++ I H A + W+ P + + D
Sbjct: 574 WSPLR-EGILCSGSDDGTVRIW-DYTQDACINILNGHTAPVRGLMWNTEIPYLLISGSWD 631
Query: 430 GTLDIWDFMFEQCDPTL 446
T+ +WD C T+
Sbjct: 632 YTIKVWDTREGTCVDTV 648
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,804,835
Number of Sequences: 37866
Number of extensions: 1121857
Number of successful extensions: 7915
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 268
Number of HSP's that attempted gapping in prelim test: 6495
Number of HSP's gapped (non-prelim): 1317
length of query: 605
length of database: 18,247,518
effective HSP length: 108
effective length of query: 497
effective length of database: 14,157,990
effective search space: 7036521030
effective search space used: 7036521030
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.