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Search of human proteins with 217416407
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|217416407 alanyl-tRNA synthetase domain containing 1 isoform
4 [Homo sapiens]
(161 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|217416407 alanyl-tRNA synthetase domain containing 1 isoform ... 346 4e-96
gi|217416402 alanyl-tRNA synthetase domain containing 1 isoform ... 304 2e-83
gi|217416405 alanyl-tRNA synthetase domain containing 1 isoform ... 242 9e-65
gi|13376886 alanyl-tRNA synthetase domain containing 1 isoform 2... 221 2e-58
gi|23308579 prostaglandin-E synthase 3 [Homo sapiens] 96 2e-20
gi|239750861 PREDICTED: hypothetical protein XP_002347581 [Homo ... 43 1e-04
gi|117168248 protein tyrosine phosphatase-like A domain containi... 43 1e-04
gi|89886480 zinedin isoform 2 [Homo sapiens] 32 0.24
gi|89886477 zinedin isoform 1 [Homo sapiens] 32 0.24
gi|224586777 WD repeat domain 8 [Homo sapiens] 31 0.53
gi|13654270 LAS1-like [Homo sapiens] 30 0.90
gi|19913408 DNA topoisomerase II, beta isozyme [Homo sapiens] 29 2.0
gi|7705943 hypothetical protein LOC10826 isoform 1 [Homo sapiens] 28 2.6
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 28 3.4
gi|75677325 kinase suppressor of ras [Homo sapiens] 28 3.4
gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sap... 27 7.6
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens] 27 7.6
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 27 7.6
gi|31982906 cingulin-like 1 [Homo sapiens] 27 7.6
gi|46397353 Notch homolog 2 N-terminal like protein [Homo sapiens] 27 7.6
gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1 [... 27 9.9
gi|157738613 coiled-coil alpha-helical rod protein 1 isoform 2 [... 27 9.9
gi|157738611 coiled-coil alpha-helical rod protein 1 isoform 3 [... 27 9.9
>gi|217416407 alanyl-tRNA synthetase domain containing 1 isoform 4
[Homo sapiens]
Length = 161
Score = 346 bits (888), Expect = 4e-96
Identities = 161/161 (100%), Positives = 161/161 (100%)
Query: 1 MFSLPLNCSPDHIRRGSCWGRPQDLKIAAPAWNSKCHPGAGAAMARCKNADGVELYNEIE 60
MFSLPLNCSPDHIRRGSCWGRPQDLKIAAPAWNSKCHPGAGAAMARCKNADGVELYNEIE
Sbjct: 1 MFSLPLNCSPDHIRRGSCWGRPQDLKIAAPAWNSKCHPGAGAAMARCKNADGVELYNEIE 60
Query: 61 FYAKVNSKDSQDKRSSRSITCFVRKWKEKVAWPRLTKEDIKPVWLSVDFDNWRDWEGDEE 120
FYAKVNSKDSQDKRSSRSITCFVRKWKEKVAWPRLTKEDIKPVWLSVDFDNWRDWEGDEE
Sbjct: 61 FYAKVNSKDSQDKRSSRSITCFVRKWKEKVAWPRLTKEDIKPVWLSVDFDNWRDWEGDEE 120
Query: 121 MELAHVEHYAELLKKVSTKRPPPAMDDLDDDSDSADDATSN 161
MELAHVEHYAELLKKVSTKRPPPAMDDLDDDSDSADDATSN
Sbjct: 121 MELAHVEHYAELLKKVSTKRPPPAMDDLDDDSDSADDATSN 161
>gi|217416402 alanyl-tRNA synthetase domain containing 1 isoform 1
[Homo sapiens]
Length = 586
Score = 304 bits (778), Expect = 2e-83
Identities = 149/187 (79%), Positives = 149/187 (79%), Gaps = 38/187 (20%)
Query: 1 MFSLPLNCSPDHIRRGSCWGRPQDLKIAAPAWNSKCHPGAGAAMAR-------------- 46
MFSLPLNCSPDHIRRGSCWGRPQDLKIAAPAWNSKCHPGAGAAMAR
Sbjct: 1 MFSLPLNCSPDHIRRGSCWGRPQDLKIAAPAWNSKCHPGAGAAMARQHARTLWYDRPRYV 60
Query: 47 ------------------------CKNADGVELYNEIEFYAKVNSKDSQDKRSSRSITCF 82
CKNADGVELYNEIEFYAKVNSKDSQDKRSSRSITCF
Sbjct: 61 FMEFCVEDSTDVHVLIEDHRIVFSCKNADGVELYNEIEFYAKVNSKDSQDKRSSRSITCF 120
Query: 83 VRKWKEKVAWPRLTKEDIKPVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPP 142
VRKWKEKVAWPRLTKEDIKPVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPP
Sbjct: 121 VRKWKEKVAWPRLTKEDIKPVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPP 180
Query: 143 PAMDDLD 149
PAMDDLD
Sbjct: 181 PAMDDLD 187
>gi|217416405 alanyl-tRNA synthetase domain containing 1 isoform 3
[Homo sapiens]
Length = 166
Score = 242 bits (618), Expect = 9e-65
Identities = 128/199 (64%), Positives = 128/199 (64%), Gaps = 71/199 (35%)
Query: 1 MFSLPLNCSPDHIRRGSCWGRPQDLKIAAPAWNSKCHPGAGAAMAR-------------- 46
MFSLPLNCSPDHIRRGSCWGRPQDLKIAAPAWNSKCHPGAGAAMAR
Sbjct: 1 MFSLPLNCSPDHIRRGSCWGRPQDLKIAAPAWNSKCHPGAGAAMARQHARTLWYDRPRYV 60
Query: 47 ------------------------CKNADGVELYNEIEFYAKVNSKDSQDKRSSRSITCF 82
CKNADGVELYNEIEFYAKVNS
Sbjct: 61 FMEFCVEDSTDVHVLIEDHRIVFSCKNADGVELYNEIEFYAKVNS--------------- 105
Query: 83 VRKWKEKVAWPRLTKEDIKPVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPP 142
KPVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPP
Sbjct: 106 ------------------KPVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPP 147
Query: 143 PAMDDLDDDSDSADDATSN 161
PAMDDLDDDSDSADDATSN
Sbjct: 148 PAMDDLDDDSDSADDATSN 166
>gi|13376886 alanyl-tRNA synthetase domain containing 1 isoform 2
[Homo sapiens]
Length = 525
Score = 221 bits (564), Expect = 2e-58
Identities = 103/103 (100%), Positives = 103/103 (100%)
Query: 47 CKNADGVELYNEIEFYAKVNSKDSQDKRSSRSITCFVRKWKEKVAWPRLTKEDIKPVWLS 106
CKNADGVELYNEIEFYAKVNSKDSQDKRSSRSITCFVRKWKEKVAWPRLTKEDIKPVWLS
Sbjct: 24 CKNADGVELYNEIEFYAKVNSKDSQDKRSSRSITCFVRKWKEKVAWPRLTKEDIKPVWLS 83
Query: 107 VDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPPPAMDDLD 149
VDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPPPAMDDLD
Sbjct: 84 VDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPPPAMDDLD 126
>gi|23308579 prostaglandin-E synthase 3 [Homo sapiens]
Length = 160
Score = 95.5 bits (236), Expect = 2e-20
Identities = 43/110 (39%), Positives = 69/110 (62%), Gaps = 2/110 (1%)
Query: 50 ADGVELYNEIEFYAKVNSKDSQDKRSSRSITCFVRKWKEKVAWPRLTKEDIKPVWLSVDF 109
+D + NEI+ + ++ DS+ KR+ RSI C +RK + +WPRLTKE K WLSVDF
Sbjct: 44 SDNFKHLNEIDLFHCIDPNDSKHKRTDRSILCCLRKGESGQSWPRLTKERAKLNWLSVDF 103
Query: 110 DNWRDWEGDEEMELAHVEHYAELLKKVSTKRPP--PAMDDLDDDSDSADD 157
+NW+DWE D + ++++ + ++E++ + P +D DDDS +DD
Sbjct: 104 NNWKDWEDDSDEDMSNFDRFSEMMNNMGGDEDVDLPEVDGADDDSQDSDD 153
>gi|239750861 PREDICTED: hypothetical protein XP_002347581 [Homo
sapiens]
Length = 190
Score = 43.1 bits (100), Expect = 1e-04
Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Query: 73 KRSSRSITCFVRKWKEKVAWPRLTKEDIKPVWLSVDFDNWRDWEGDEEMELAHVEHYAEL 132
K + R + V+K K W RLTK++ +P++L+ DFD W D E D EMEL E
Sbjct: 72 KLTQRQVNITVQK-KVSQWWERLTKQEKRPLFLAPDFDRWLD-ESDAEMELRAKEEERLN 129
Query: 133 LKKVSTKRPPPAMDDL 148
++ ++ P + +L
Sbjct: 130 KLRLESEGSPETLTNL 145
>gi|117168248 protein tyrosine phosphatase-like A domain containing
1 [Homo sapiens]
Length = 362
Score = 43.1 bits (100), Expect = 1e-04
Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Query: 73 KRSSRSITCFVRKWKEKVAWPRLTKEDIKPVWLSVDFDNWRDWEGDEEMELAHVEHYAEL 132
K + R + V+K K W RLTK++ +P++L+ DFD W D E D EMEL E
Sbjct: 72 KLTQRQVNITVQK-KVSQWWERLTKQEKRPLFLAPDFDRWLD-ESDAEMELRAKEEERLN 129
Query: 133 LKKVSTKRPPPAMDDL 148
++ ++ P + +L
Sbjct: 130 KLRLESEGSPETLTNL 145
>gi|89886480 zinedin isoform 2 [Homo sapiens]
Length = 760
Score = 32.0 bits (71), Expect = 0.24
Identities = 17/46 (36%), Positives = 27/46 (58%), Gaps = 1/46 (2%)
Query: 111 NWRDWEGDEEMELAHVEHYAELLKKVSTKRPPPAMDDLDDDSDSAD 156
N D + DE+ EL V+H + + K+ +K P M+D D++ DS D
Sbjct: 270 NCEDEDSDEDDELDSVQHKKQRV-KLPSKALVPEMEDEDEEDDSED 314
>gi|89886477 zinedin isoform 1 [Homo sapiens]
Length = 753
Score = 32.0 bits (71), Expect = 0.24
Identities = 17/46 (36%), Positives = 27/46 (58%), Gaps = 1/46 (2%)
Query: 111 NWRDWEGDEEMELAHVEHYAELLKKVSTKRPPPAMDDLDDDSDSAD 156
N D + DE+ EL V+H + + K+ +K P M+D D++ DS D
Sbjct: 270 NCEDEDSDEDDELDSVQHKKQRV-KLPSKALVPEMEDEDEEDDSED 314
>gi|224586777 WD repeat domain 8 [Homo sapiens]
Length = 460
Score = 30.8 bits (68), Expect = 0.53
Identities = 13/46 (28%), Positives = 22/46 (47%)
Query: 20 GRPQDLKIAAPAWNSKCHPGAGAAMARCKNADGVELYNEIEFYAKV 65
G Q + P W+ K G+ +A C + DG + N EF+ ++
Sbjct: 71 GLVQVWSLEQPEWHCKIDEGSAGLVASCWSPDGRHILNTTEFHLRI 116
>gi|13654270 LAS1-like [Homo sapiens]
Length = 734
Score = 30.0 bits (66), Expect = 0.90
Identities = 18/79 (22%), Positives = 35/79 (44%), Gaps = 7/79 (8%)
Query: 82 FVRKWKEKVAWPRLTKEDIKPVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRP 141
FV W +K W R + ++ W + + +R+ +E+ E E ++ ++ ++P
Sbjct: 175 FVLDWLQKTYWCRQLENSLRETW---ELEEFREGIEEEDQE----EDKNIVVDDITEQKP 227
Query: 142 PPAMDDLDDDSDSADDATS 160
P D +SD D S
Sbjct: 228 EPQDDGKSTESDVKADGDS 246
>gi|19913408 DNA topoisomerase II, beta isozyme [Homo sapiens]
Length = 1621
Score = 28.9 bits (63), Expect = 2.0
Identities = 15/50 (30%), Positives = 23/50 (46%), Gaps = 4/50 (8%)
Query: 112 WRDWEGDEEMELAHVEHYA----ELLKKVSTKRPPPAMDDLDDDSDSADD 157
W D E E +L E LL++ + +RP D +++ D ADD
Sbjct: 1330 WSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADD 1379
>gi|7705943 hypothetical protein LOC10826 isoform 1 [Homo sapiens]
Length = 144
Score = 28.5 bits (62), Expect = 2.6
Identities = 13/34 (38%), Positives = 18/34 (52%), Gaps = 6/34 (17%)
Query: 17 SCWGRPQDLKIAAP---AWNS---KCHPGAGAAM 44
SCW P+ L+ + W+ KCHPG +AM
Sbjct: 54 SCWASPRSLRASQTPQRGWSERQPKCHPGCPSAM 87
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 28.1 bits (61), Expect = 3.4
Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 5/68 (7%)
Query: 93 PRLTKEDIKPVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPPPAMDDLDDDS 152
P+ E +PV S D + D +EE + + + +T +PPPA + S
Sbjct: 309 PKKAVEKQQPVESSEDSSDESDSSSEEEKKPP-----TKAVVSKATTKPPPAKKAAESSS 363
Query: 153 DSADDATS 160
DS+D +S
Sbjct: 364 DSSDSDSS 371
>gi|75677325 kinase suppressor of ras [Homo sapiens]
Length = 762
Score = 28.1 bits (61), Expect = 3.4
Identities = 12/33 (36%), Positives = 19/33 (57%)
Query: 128 HYAELLKKVSTKRPPPAMDDLDDDSDSADDATS 160
H+ L K ++ K PPAM+ LD S+ + +S
Sbjct: 285 HFGTLPKALTKKEHPPAMNHLDSSSNPSSTTSS 317
>gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo
sapiens]
Length = 1270
Score = 26.9 bits (58), Expect = 7.6
Identities = 12/24 (50%), Positives = 14/24 (58%)
Query: 9 SPDHIRRGSCWGRPQDLKIAAPAW 32
SP IRR S G+P LK A +W
Sbjct: 752 SPQRIRRVSSSGKPTSLKTAQSSW 775
>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
Length = 710
Score = 26.9 bits (58), Expect = 7.6
Identities = 14/44 (31%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 116 EGDEEMELAHVEHYAELLKKVSTKRPPPAMDDLDDDSDSADDAT 159
E D + +A + Y E K+VS+ R P+++ D+ DS + T
Sbjct: 412 EKDSVLNIARGKKYGEKTKRVSS-RKKPSLEATSDEKDSFSNIT 454
>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 948
Score = 26.9 bits (58), Expect = 7.6
Identities = 14/44 (31%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 116 EGDEEMELAHVEHYAELLKKVSTKRPPPAMDDLDDDSDSADDAT 159
E D + +A + Y E K+VS+ R P+++ D+ DS + T
Sbjct: 584 EKDSVLNIARGKKYGEKTKRVSS-RKKPSLEATSDEKDSFSNIT 626
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 26.9 bits (58), Expect = 7.6
Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query: 116 EGDEEMEL-AHVEHYAELLKKVST--KRPPPAMDDLDDDSDSADDATS 160
E +E+M++ H++ +KK K P +DD+DDD D + D S
Sbjct: 1235 ELEEQMDMNEHLQGQLNSMKKDLRLKKLPSKVLDDMDDDDDLSTDGGS 1282
>gi|46397353 Notch homolog 2 N-terminal like protein [Homo sapiens]
Length = 236
Score = 26.9 bits (58), Expect = 7.6
Identities = 13/37 (35%), Positives = 20/37 (54%), Gaps = 7/37 (18%)
Query: 2 FSLPLNCSPDHIRRGS-CWGRPQDLKIAAPAWNSKCH 37
F+ NC P+ +RRG+ W R +++ WN K H
Sbjct: 203 FTFECNCLPETVRRGTELWERDREV------WNGKEH 233
>gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1
[Homo sapiens]
Length = 871
Score = 26.6 bits (57), Expect = 9.9
Identities = 14/54 (25%), Positives = 22/54 (40%)
Query: 37 HPGAGAAMARCKNADGVELYNEIEFYAKVNSKDSQDKRSSRSITCFVRKWKEKV 90
H A R ++ + E E KV DS + +R + +W+EKV
Sbjct: 377 HATAELLQVRVQSLTHILALQEEELTRKVQPSDSLEPEFTRKCQSLLNRWREKV 430
>gi|157738613 coiled-coil alpha-helical rod protein 1 isoform 2
[Homo sapiens]
Length = 835
Score = 26.6 bits (57), Expect = 9.9
Identities = 14/54 (25%), Positives = 22/54 (40%)
Query: 37 HPGAGAAMARCKNADGVELYNEIEFYAKVNSKDSQDKRSSRSITCFVRKWKEKV 90
H A R ++ + E E KV DS + +R + +W+EKV
Sbjct: 341 HATAELLQVRVQSLTHILALQEEELTRKVQPSDSLEPEFTRKCQSLLNRWREKV 394
>gi|157738611 coiled-coil alpha-helical rod protein 1 isoform 3
[Homo sapiens]
Length = 782
Score = 26.6 bits (57), Expect = 9.9
Identities = 14/54 (25%), Positives = 22/54 (40%)
Query: 37 HPGAGAAMARCKNADGVELYNEIEFYAKVNSKDSQDKRSSRSITCFVRKWKEKV 90
H A R ++ + E E KV DS + +R + +W+EKV
Sbjct: 288 HATAELLQVRVQSLTHILALQEEELTRKVQPSDSLEPEFTRKCQSLLNRWREKV 341
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,241,544
Number of Sequences: 37866
Number of extensions: 305955
Number of successful extensions: 908
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 880
Number of HSP's gapped (non-prelim): 35
length of query: 161
length of database: 18,247,518
effective HSP length: 94
effective length of query: 67
effective length of database: 14,688,114
effective search space: 984103638
effective search space used: 984103638
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.