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Search of human proteins with 217416405
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|217416405 alanyl-tRNA synthetase domain containing 1 isoform
3 [Homo sapiens]
(166 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|217416405 alanyl-tRNA synthetase domain containing 1 isoform ... 359 e-100
gi|217416402 alanyl-tRNA synthetase domain containing 1 isoform ... 318 1e-87
gi|217416407 alanyl-tRNA synthetase domain containing 1 isoform ... 242 9e-65
gi|13376886 alanyl-tRNA synthetase domain containing 1 isoform 2... 183 7e-47
gi|23308579 prostaglandin-E synthase 3 [Homo sapiens] 90 1e-18
gi|89886480 zinedin isoform 2 [Homo sapiens] 32 0.25
gi|89886477 zinedin isoform 1 [Homo sapiens] 32 0.25
gi|239750861 PREDICTED: hypothetical protein XP_002347581 [Homo ... 31 0.43
gi|117168248 protein tyrosine phosphatase-like A domain containi... 31 0.43
gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens] 31 0.56
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] 31 0.56
gi|7705943 hypothetical protein LOC10826 isoform 1 [Homo sapiens] 31 0.56
gi|19913408 DNA topoisomerase II, beta isozyme [Homo sapiens] 29 2.1
gi|75677325 kinase suppressor of ras [Homo sapiens] 28 3.6
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens] 27 6.1
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 27 6.1
gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sap... 27 8.0
gi|31982906 cingulin-like 1 [Homo sapiens] 27 8.0
gi|46397353 Notch homolog 2 N-terminal like protein [Homo sapiens] 27 8.0
>gi|217416405 alanyl-tRNA synthetase domain containing 1 isoform 3
[Homo sapiens]
Length = 166
Score = 359 bits (921), Expect = e-100
Identities = 166/166 (100%), Positives = 166/166 (100%)
Query: 1 MFSLPLNCSPDHIRRGSCWGRPQDLKIAAPAWNSKCHPGAGAAMARQHARTLWYDRPRYV 60
MFSLPLNCSPDHIRRGSCWGRPQDLKIAAPAWNSKCHPGAGAAMARQHARTLWYDRPRYV
Sbjct: 1 MFSLPLNCSPDHIRRGSCWGRPQDLKIAAPAWNSKCHPGAGAAMARQHARTLWYDRPRYV 60
Query: 61 FMEFCVEDSTDVHVLIEDHRIVFSCKNADGVELYNEIEFYAKVNSKPVWLSVDFDNWRDW 120
FMEFCVEDSTDVHVLIEDHRIVFSCKNADGVELYNEIEFYAKVNSKPVWLSVDFDNWRDW
Sbjct: 61 FMEFCVEDSTDVHVLIEDHRIVFSCKNADGVELYNEIEFYAKVNSKPVWLSVDFDNWRDW 120
Query: 121 EGDEEMELAHVEHYAELLKKVSTKRPPPAMDDLDDDSDSADDATSN 166
EGDEEMELAHVEHYAELLKKVSTKRPPPAMDDLDDDSDSADDATSN
Sbjct: 121 EGDEEMELAHVEHYAELLKKVSTKRPPPAMDDLDDDSDSADDATSN 166
>gi|217416402 alanyl-tRNA synthetase domain containing 1 isoform 1
[Homo sapiens]
Length = 586
Score = 318 bits (816), Expect = 1e-87
Identities = 154/187 (82%), Positives = 154/187 (82%), Gaps = 33/187 (17%)
Query: 1 MFSLPLNCSPDHIRRGSCWGRPQDLKIAAPAWNSKCHPGAGAAMARQHARTLWYDRPRYV 60
MFSLPLNCSPDHIRRGSCWGRPQDLKIAAPAWNSKCHPGAGAAMARQHARTLWYDRPRYV
Sbjct: 1 MFSLPLNCSPDHIRRGSCWGRPQDLKIAAPAWNSKCHPGAGAAMARQHARTLWYDRPRYV 60
Query: 61 FMEFCVEDSTDVHVLIEDHRIVFSCKNADGVELYNEIEFYAKVNS--------------- 105
FMEFCVEDSTDVHVLIEDHRIVFSCKNADGVELYNEIEFYAKVNS
Sbjct: 61 FMEFCVEDSTDVHVLIEDHRIVFSCKNADGVELYNEIEFYAKVNSKDSQDKRSSRSITCF 120
Query: 106 ------------------KPVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPP 147
KPVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPP
Sbjct: 121 VRKWKEKVAWPRLTKEDIKPVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPP 180
Query: 148 PAMDDLD 154
PAMDDLD
Sbjct: 181 PAMDDLD 187
>gi|217416407 alanyl-tRNA synthetase domain containing 1 isoform 4
[Homo sapiens]
Length = 161
Score = 242 bits (618), Expect = 9e-65
Identities = 128/199 (64%), Positives = 128/199 (64%), Gaps = 71/199 (35%)
Query: 1 MFSLPLNCSPDHIRRGSCWGRPQDLKIAAPAWNSKCHPGAGAAMARQHARTLWYDRPRYV 60
MFSLPLNCSPDHIRRGSCWGRPQDLKIAAPAWNSKCHPGAGAAMAR
Sbjct: 1 MFSLPLNCSPDHIRRGSCWGRPQDLKIAAPAWNSKCHPGAGAAMAR-------------- 46
Query: 61 FMEFCVEDSTDVHVLIEDHRIVFSCKNADGVELYNEIEFYAKVNS--------------- 105
CKNADGVELYNEIEFYAKVNS
Sbjct: 47 ------------------------CKNADGVELYNEIEFYAKVNSKDSQDKRSSRSITCF 82
Query: 106 ------------------KPVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPP 147
KPVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPP
Sbjct: 83 VRKWKEKVAWPRLTKEDIKPVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPP 142
Query: 148 PAMDDLDDDSDSADDATSN 166
PAMDDLDDDSDSADDATSN
Sbjct: 143 PAMDDLDDDSDSADDATSN 161
>gi|13376886 alanyl-tRNA synthetase domain containing 1 isoform 2
[Homo sapiens]
Length = 525
Score = 183 bits (464), Expect = 7e-47
Identities = 93/126 (73%), Positives = 93/126 (73%), Gaps = 33/126 (26%)
Query: 62 MEFCVEDSTDVHVLIEDHRIVFSCKNADGVELYNEIEFYAKVNSK--------------- 106
MEFCVEDSTDVHVLIEDHRIVFSCKNADGVELYNEIEFYAKVNSK
Sbjct: 1 MEFCVEDSTDVHVLIEDHRIVFSCKNADGVELYNEIEFYAKVNSKDSQDKRSSRSITCFV 60
Query: 107 ------------------PVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPPP 148
PVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPPP
Sbjct: 61 RKWKEKVAWPRLTKEDIKPVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPPP 120
Query: 149 AMDDLD 154
AMDDLD
Sbjct: 121 AMDDLD 126
>gi|23308579 prostaglandin-E synthase 3 [Homo sapiens]
Length = 160
Score = 89.7 bits (221), Expect = 1e-18
Identities = 50/152 (32%), Positives = 74/152 (48%), Gaps = 36/152 (23%)
Query: 47 QHARTLWYDRPRYVFMEFCVEDSTDVHVLIEDHRIVFSCKN-ADGVELYNEIEFY----- 100
Q A WYDR YVF+EFCVEDS DV+V E ++ FSC +D + NEI+ +
Sbjct: 2 QPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLFHCIDP 61
Query: 101 ----------------------------AKVNSKPVWLSVDFDNWRDWEGDEEMELAHVE 132
K +K WLSVDF+NW+DWE D + ++++ +
Sbjct: 62 NDSKHKRTDRSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDEDMSNFD 121
Query: 133 HYAELLKKVSTKRPP--PAMDDLDDDSDSADD 162
++E++ + P +D DDDS +DD
Sbjct: 122 RFSEMMNNMGGDEDVDLPEVDGADDDSQDSDD 153
>gi|89886480 zinedin isoform 2 [Homo sapiens]
Length = 760
Score = 32.0 bits (71), Expect = 0.25
Identities = 17/46 (36%), Positives = 27/46 (58%), Gaps = 1/46 (2%)
Query: 116 NWRDWEGDEEMELAHVEHYAELLKKVSTKRPPPAMDDLDDDSDSAD 161
N D + DE+ EL V+H + + K+ +K P M+D D++ DS D
Sbjct: 270 NCEDEDSDEDDELDSVQHKKQRV-KLPSKALVPEMEDEDEEDDSED 314
>gi|89886477 zinedin isoform 1 [Homo sapiens]
Length = 753
Score = 32.0 bits (71), Expect = 0.25
Identities = 17/46 (36%), Positives = 27/46 (58%), Gaps = 1/46 (2%)
Query: 116 NWRDWEGDEEMELAHVEHYAELLKKVSTKRPPPAMDDLDDDSDSAD 161
N D + DE+ EL V+H + + K+ +K P M+D D++ DS D
Sbjct: 270 NCEDEDSDEDDELDSVQHKKQRV-KLPSKALVPEMEDEDEEDDSED 314
>gi|239750861 PREDICTED: hypothetical protein XP_002347581 [Homo
sapiens]
Length = 190
Score = 31.2 bits (69), Expect = 0.43
Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 98 EFYAKVNSKPVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPPPAMDDL 153
E K +P++L+ DFD W D E D EMEL E ++ ++ P + +L
Sbjct: 91 ERLTKQEKRPLFLAPDFDRWLD-ESDAEMELRAKEEERLNKLRLESEGSPETLTNL 145
>gi|117168248 protein tyrosine phosphatase-like A domain containing
1 [Homo sapiens]
Length = 362
Score = 31.2 bits (69), Expect = 0.43
Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 98 EFYAKVNSKPVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPPPAMDDL 153
E K +P++L+ DFD W D E D EMEL E ++ ++ P + +L
Sbjct: 91 ERLTKQEKRPLFLAPDFDRWLD-ESDAEMELRAKEEERLNKLRLESEGSPETLTNL 145
>gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens]
Length = 1226
Score = 30.8 bits (68), Expect = 0.56
Identities = 38/176 (21%), Positives = 73/176 (41%), Gaps = 39/176 (22%)
Query: 11 DHIRRGSCWGRP-QDLKI----AAPAWNSKCHPGAGAAMARQHARTLWYDRPRYVFMEFC 65
D+I G+ W + QDL I +A +N KC Y + Y F E+C
Sbjct: 354 DNIESGAVWKQVYQDLGIPVLNSAAGYNVKCA----------------YKKYLYGFEEYC 397
Query: 66 VEDSTDVHVLIEDHRIVFSCKNADGVE----------LYNEIEFYAKVN-----SKPVWL 110
+ + + + + + CK + V+ EI+ + N KP+
Sbjct: 398 RSANIEFQMALPEKVVNKQCKECENVKEIKVKEENETEIKEIKMEEERNIIPREEKPIED 457
Query: 111 SVD-FDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPP--PAMDDLDDDSDSADDA 163
++ +N + G ++ L + +++ K+V+ K+P +DD DDD+ D++
Sbjct: 458 EIERKENIKPSLGSKKNLLESIPTHSDQEKEVNIKKPEDNENLDDKDDDTTRVDES 513
>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
Length = 1312
Score = 30.8 bits (68), Expect = 0.56
Identities = 38/176 (21%), Positives = 73/176 (41%), Gaps = 39/176 (22%)
Query: 11 DHIRRGSCWGRP-QDLKI----AAPAWNSKCHPGAGAAMARQHARTLWYDRPRYVFMEFC 65
D+I G+ W + QDL I +A +N KC Y + Y F E+C
Sbjct: 354 DNIESGAVWKQVYQDLGIPVLNSAAGYNVKCA----------------YKKYLYGFEEYC 397
Query: 66 VEDSTDVHVLIEDHRIVFSCKNADGVE----------LYNEIEFYAKVN-----SKPVWL 110
+ + + + + + CK + V+ EI+ + N KP+
Sbjct: 398 RSANIEFQMALPEKVVNKQCKECENVKEIKVKEENETEIKEIKMEEERNIIPREEKPIED 457
Query: 111 SVD-FDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPP--PAMDDLDDDSDSADDA 163
++ +N + G ++ L + +++ K+V+ K+P +DD DDD+ D++
Sbjct: 458 EIERKENIKPSLGSKKNLLESIPTHSDQEKEVNIKKPEDNENLDDKDDDTTRVDES 513
>gi|7705943 hypothetical protein LOC10826 isoform 1 [Homo sapiens]
Length = 144
Score = 30.8 bits (68), Expect = 0.56
Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 6/38 (15%)
Query: 17 SCWGRPQDLKIAAP---AWNS---KCHPGAGAAMARQH 48
SCW P+ L+ + W+ KCHPG +AM +H
Sbjct: 54 SCWASPRSLRASQTPQRGWSERQPKCHPGCPSAMGCRH 91
>gi|19913408 DNA topoisomerase II, beta isozyme [Homo sapiens]
Length = 1621
Score = 28.9 bits (63), Expect = 2.1
Identities = 15/50 (30%), Positives = 23/50 (46%), Gaps = 4/50 (8%)
Query: 117 WRDWEGDEEMELAHVEHYA----ELLKKVSTKRPPPAMDDLDDDSDSADD 162
W D E E +L E LL++ + +RP D +++ D ADD
Sbjct: 1330 WSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADD 1379
>gi|75677325 kinase suppressor of ras [Homo sapiens]
Length = 762
Score = 28.1 bits (61), Expect = 3.6
Identities = 12/33 (36%), Positives = 19/33 (57%)
Query: 133 HYAELLKKVSTKRPPPAMDDLDDDSDSADDATS 165
H+ L K ++ K PPAM+ LD S+ + +S
Sbjct: 285 HFGTLPKALTKKEHPPAMNHLDSSSNPSSTTSS 317
>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
Length = 710
Score = 27.3 bits (59), Expect = 6.1
Identities = 18/61 (29%), Positives = 29/61 (47%), Gaps = 6/61 (9%)
Query: 104 NSKPVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPPPAMDDLDDDSDSADDA 163
+ KP L D E D + +A + Y E K+VS+ R P+++ D+ DS +
Sbjct: 400 SEKPPGLKASSD-----EKDSVLNIARGKKYGEKTKRVSS-RKKPSLEATSDEKDSFSNI 453
Query: 164 T 164
T
Sbjct: 454 T 454
>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 948
Score = 27.3 bits (59), Expect = 6.1
Identities = 18/61 (29%), Positives = 29/61 (47%), Gaps = 6/61 (9%)
Query: 104 NSKPVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPPPAMDDLDDDSDSADDA 163
+ KP L D E D + +A + Y E K+VS+ R P+++ D+ DS +
Sbjct: 572 SEKPPGLKASSD-----EKDSVLNIARGKKYGEKTKRVSS-RKKPSLEATSDEKDSFSNI 625
Query: 164 T 164
T
Sbjct: 626 T 626
>gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo
sapiens]
Length = 1270
Score = 26.9 bits (58), Expect = 8.0
Identities = 12/24 (50%), Positives = 14/24 (58%)
Query: 9 SPDHIRRGSCWGRPQDLKIAAPAW 32
SP IRR S G+P LK A +W
Sbjct: 752 SPQRIRRVSSSGKPTSLKTAQSSW 775
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 26.9 bits (58), Expect = 8.0
Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query: 121 EGDEEMEL-AHVEHYAELLKKVST--KRPPPAMDDLDDDSDSADDATS 165
E +E+M++ H++ +KK K P +DD+DDD D + D S
Sbjct: 1235 ELEEQMDMNEHLQGQLNSMKKDLRLKKLPSKVLDDMDDDDDLSTDGGS 1282
>gi|46397353 Notch homolog 2 N-terminal like protein [Homo sapiens]
Length = 236
Score = 26.9 bits (58), Expect = 8.0
Identities = 13/37 (35%), Positives = 20/37 (54%), Gaps = 7/37 (18%)
Query: 2 FSLPLNCSPDHIRRGS-CWGRPQDLKIAAPAWNSKCH 37
F+ NC P+ +RRG+ W R +++ WN K H
Sbjct: 203 FTFECNCLPETVRRGTELWERDREV------WNGKEH 233
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.442
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,533,471
Number of Sequences: 37866
Number of extensions: 329416
Number of successful extensions: 875
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 856
Number of HSP's gapped (non-prelim): 29
length of query: 166
length of database: 18,247,518
effective HSP length: 95
effective length of query: 71
effective length of database: 14,650,248
effective search space: 1040167608
effective search space used: 1040167608
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.