Search of human proteins with 217330594

Search of human proteins with 217330594

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|217330594 tubulin tyrosine ligase-like family, member 4
[Homo sapiens]
         (1199 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo...  2425   0.0  
gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo ...   300   4e-81
gi|195963418 tubulin tyrosine ligase-like family, member 6 isofo...   221   3e-57
gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo ...   202   2e-51
gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo ...   201   5e-51
gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo...   197   4e-50
gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo ...   177   4e-44
gi|212720861 tubulin tyrosine ligase-like family, member 11 a [H...   164   5e-40
gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Ho...   132   2e-30
gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo ...   132   2e-30
gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo...    96   2e-19
gi|194239681 tubulin tyrosine ligase-like family, member 10 isof...    93   2e-18
gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo...    92   2e-18
gi|24308516 tubulin tyrosine ligase [Homo sapiens]                     88   4e-17
gi|195963416 tubulin tyrosine ligase-like family, member 6 isofo...    75   3e-13
gi|194239678 tubulin tyrosine ligase-like family, member 10 isof...    66   2e-10
gi|55741677 SET domain containing 1A [Homo sapiens]                    49   4e-05
gi|11056036 tubulin tyrosine ligase-like family, member 12 [Homo...    46   2e-04
gi|19923844 coiled-coil domain containing 82 [Homo sapiens]            43   0.002
gi|167736355 mucin 4 isoform a [Homo sapiens]                          41   0.008
gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi...    39   0.039
gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi...    39   0.039
gi|156071452 nardilysin isoform b [Homo sapiens]                       37   0.11 
gi|4503257 death-domain associated protein isoform a [Homo sapiens]    37   0.15 
gi|215422388 death-domain associated protein isoform a [Homo sap...    37   0.15 
gi|215422366 death-domain associated protein isoform b [Homo sap...    37   0.15 
gi|115529449 upstream binding transcription factor, RNA polymera...    37   0.15 
gi|115529451 upstream binding transcription factor, RNA polymera...    37   0.15 
gi|7657671 upstream binding transcription factor, RNA polymerase...    37   0.15 
gi|210032580 SET domain containing 1B [Homo sapiens]                   37   0.15 

>gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo
            sapiens]
          Length = 1199

 Score = 2425 bits (6286), Expect = 0.0
 Identities = 1199/1199 (100%), Positives = 1199/1199 (100%)

Query: 1    MASAGTQHYSIGLRQKNSFKQSGPSGTVPATPPEKPSEGRVWPQAHQQVKPIWKLEKKQV 60
            MASAGTQHYSIGLRQKNSFKQSGPSGTVPATPPEKPSEGRVWPQAHQQVKPIWKLEKKQV
Sbjct: 1    MASAGTQHYSIGLRQKNSFKQSGPSGTVPATPPEKPSEGRVWPQAHQQVKPIWKLEKKQV 60

Query: 61   ETLSAGLGPGLLGVPPQPAYFFCPSTLCSSGTTAVIAGHSSSCYLHSLPDLFNSTLLYRR 120
            ETLSAGLGPGLLGVPPQPAYFFCPSTLCSSGTTAVIAGHSSSCYLHSLPDLFNSTLLYRR
Sbjct: 61   ETLSAGLGPGLLGVPPQPAYFFCPSTLCSSGTTAVIAGHSSSCYLHSLPDLFNSTLLYRR 120

Query: 121  SSYRQKPYQQLESFCLRSSPSEKSPFSLPQKSLPVSLTANKATSSMVFSMAQPMASSSTE 180
            SSYRQKPYQQLESFCLRSSPSEKSPFSLPQKSLPVSLTANKATSSMVFSMAQPMASSSTE
Sbjct: 121  SSYRQKPYQQLESFCLRSSPSEKSPFSLPQKSLPVSLTANKATSSMVFSMAQPMASSSTE 180

Query: 181  PYLCLAAAGENPSGKSLASAISGKIPSPLSSSYKPMLNNNSFMWPNSTPVPLLQTTQGLK 240
            PYLCLAAAGENPSGKSLASAISGKIPSPLSSSYKPMLNNNSFMWPNSTPVPLLQTTQGLK
Sbjct: 181  PYLCLAAAGENPSGKSLASAISGKIPSPLSSSYKPMLNNNSFMWPNSTPVPLLQTTQGLK 240

Query: 241  PVSPPKIQPVSWHHSGGTGDCAPQPVDHKVPKSIGTVPADASAHIALSTASSHDTSTTSV 300
            PVSPPKIQPVSWHHSGGTGDCAPQPVDHKVPKSIGTVPADASAHIALSTASSHDTSTTSV
Sbjct: 241  PVSPPKIQPVSWHHSGGTGDCAPQPVDHKVPKSIGTVPADASAHIALSTASSHDTSTTSV 300

Query: 301  ASSWYNRNNLAMRAEPLSCALDDSSDSQDPTKEIRFTEAVRKLTARGFEKMPRQGCQLEQ 360
            ASSWYNRNNLAMRAEPLSCALDDSSDSQDPTKEIRFTEAVRKLTARGFEKMPRQGCQLEQ
Sbjct: 301  ASSWYNRNNLAMRAEPLSCALDDSSDSQDPTKEIRFTEAVRKLTARGFEKMPRQGCQLEQ 360

Query: 361  SSFLNPSFQWNVLNRSRRWKPPAVNQQFPQEDAGSVRRVLPGASDTLGLDNTVFCTKRIS 420
            SSFLNPSFQWNVLNRSRRWKPPAVNQQFPQEDAGSVRRVLPGASDTLGLDNTVFCTKRIS
Sbjct: 361  SSFLNPSFQWNVLNRSRRWKPPAVNQQFPQEDAGSVRRVLPGASDTLGLDNTVFCTKRIS 420

Query: 421  IHLLASHASGLNHNPACESVIDSSAFGEGKAPGPPFPQTLGIANVATRLSSIQLGQSEKE 480
            IHLLASHASGLNHNPACESVIDSSAFGEGKAPGPPFPQTLGIANVATRLSSIQLGQSEKE
Sbjct: 421  IHLLASHASGLNHNPACESVIDSSAFGEGKAPGPPFPQTLGIANVATRLSSIQLGQSEKE 480

Query: 481  RPEEARELDSSDRDISSATDLQPDQAETEDTEEELVDGLEDCCSRDENEEEEGDSECSSL 540
            RPEEARELDSSDRDISSATDLQPDQAETEDTEEELVDGLEDCCSRDENEEEEGDSECSSL
Sbjct: 481  RPEEARELDSSDRDISSATDLQPDQAETEDTEEELVDGLEDCCSRDENEEEEGDSECSSL 540

Query: 541  SAVSPSESVAMISRSCMEILTKPLSNHEKVVRPALIYSLFPNVPPTIYFGTRDERVEKLP 600
            SAVSPSESVAMISRSCMEILTKPLSNHEKVVRPALIYSLFPNVPPTIYFGTRDERVEKLP
Sbjct: 541  SAVSPSESVAMISRSCMEILTKPLSNHEKVVRPALIYSLFPNVPPTIYFGTRDERVEKLP 600

Query: 601  WEQRKLLRWKMSTVTPNIVKQTIGRSHFKISKRNDDWLGCWGHHMKSPSFRSIREHQKLN 660
            WEQRKLLRWKMSTVTPNIVKQTIGRSHFKISKRNDDWLGCWGHHMKSPSFRSIREHQKLN
Sbjct: 601  WEQRKLLRWKMSTVTPNIVKQTIGRSHFKISKRNDDWLGCWGHHMKSPSFRSIREHQKLN 660

Query: 661  HFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQDAKLLRKAWESSSRQKWIV 720
            HFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQDAKLLRKAWESSSRQKWIV
Sbjct: 661  HFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQDAKLLRKAWESSSRQKWIV 720

Query: 721  KPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKFDLRIYVYVTSYDPLRIY 780
            KPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKFDLRIYVYVTSYDPLRIY
Sbjct: 721  KPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKFDLRIYVYVTSYDPLRIY 780

Query: 781  LFSDGLVRFASCKYSPSMKSLGNKFMHLTNYSVNKKNAEYQANADEMACQGHKWALKALW 840
            LFSDGLVRFASCKYSPSMKSLGNKFMHLTNYSVNKKNAEYQANADEMACQGHKWALKALW
Sbjct: 781  LFSDGLVRFASCKYSPSMKSLGNKFMHLTNYSVNKKNAEYQANADEMACQGHKWALKALW 840

Query: 841  NYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTSLLKMYVRRPYSCHELFGFDIMLDENL 900
            NYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTSLLKMYVRRPYSCHELFGFDIMLDENL
Sbjct: 841  NYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTSLLKMYVRRPYSCHELFGFDIMLDENL 900

Query: 901  KPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNLAGFVLPNAEDIISSPSSCSSSTTSLP 960
            KPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNLAGFVLPNAEDIISSPSSCSSSTTSLP
Sbjct: 901  KPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNLAGFVLPNAEDIISSPSSCSSSTTSLP 960

Query: 961  TSPGDKCRMAPEHVTAQKMKKAYYLTQKIPDQDFYASVLDVLTPDDVRILVEMEDEFSRR 1020
            TSPGDKCRMAPEHVTAQKMKKAYYLTQKIPDQDFYASVLDVLTPDDVRILVEMEDEFSRR
Sbjct: 961  TSPGDKCRMAPEHVTAQKMKKAYYLTQKIPDQDFYASVLDVLTPDDVRILVEMEDEFSRR 1020

Query: 1021 GQFERIFPSHISSRYLRFFEQPRYFNILTTQWEQKYHGNKLKGVDLLRSWCYKGFHMGVV 1080
            GQFERIFPSHISSRYLRFFEQPRYFNILTTQWEQKYHGNKLKGVDLLRSWCYKGFHMGVV
Sbjct: 1021 GQFERIFPSHISSRYLRFFEQPRYFNILTTQWEQKYHGNKLKGVDLLRSWCYKGFHMGVV 1080

Query: 1081 SDSAPVWSLPTSLLTISKDDVILNAFSKSETSKLGKQSSCEVSLLLSEDGTTPKSKKTQA 1140
            SDSAPVWSLPTSLLTISKDDVILNAFSKSETSKLGKQSSCEVSLLLSEDGTTPKSKKTQA
Sbjct: 1081 SDSAPVWSLPTSLLTISKDDVILNAFSKSETSKLGKQSSCEVSLLLSEDGTTPKSKKTQA 1140

Query: 1141 GLSPYPQKPSSSKDSEDTSKEPSLSTQTLPVIKCSGQTSRLSASSTFQSISDSLLAVSP 1199
            GLSPYPQKPSSSKDSEDTSKEPSLSTQTLPVIKCSGQTSRLSASSTFQSISDSLLAVSP
Sbjct: 1141 GLSPYPQKPSSSKDSEDTSKEPSLSTQTLPVIKCSGQTSRLSASSTFQSISDSLLAVSP 1199


>gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo
            sapiens]
          Length = 1281

 Score =  300 bits (769), Expect = 4e-81
 Identities = 169/444 (38%), Positives = 264/444 (59%), Gaps = 11/444 (2%)

Query: 591  TRDERVEKLPWEQRKLLRWKMSTVTPNIVKQTIGRSHF-KISKRNDDWLGCW-GHHMKSP 648
            T+D  +  +   +R  L +K+      +V+  +    F ++   + D+   W G H+K  
Sbjct: 51   TKDNNIRVIG--ERYHLSYKIVRTDSRLVRSILTAHGFHEVHPSSTDYNLMWTGSHLKPF 108

Query: 649  SFRSIREHQKLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQDAKLLRK 708
              R++ E QK+NHFP S+++ RKDRL++N+ RMQ   G K F   PQ+F+LP +      
Sbjct: 109  LLRTLSEAQKVNHFPRSYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCN 168

Query: 709  AWESSSRQKWIVKPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKFDLRIY 768
            ++ S  R  WIVKP AS+RG G+ +I+  +Q+     +LV RY++ P LI   KFD+R+Y
Sbjct: 169  SY-SKDRGPWIVKPVASSRGRGVYLINNPNQISLEENILVSRYINNPLLIDDFKFDVRLY 227

Query: 769  VYVTSYDPLRIYLFSDGLVRFASCKYSPSMKSLGNKFMHLTNYSVNKKNAEYQANAD-EM 827
            V VTSYDPL IYL+ +GL RFA+ +Y    K++ N+FMHLTNYSVNKK+ +Y +  D E+
Sbjct: 228  VLVTSYDPLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLTNYSVNKKSGDYVSCDDPEV 287

Query: 828  ACQGHKWALKALWNYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTSLLKMYVRRPYSCH 887
               G+KW++ A+  YL Q+G ++ A+   ++D+++KTIIS+E  + +  K +V    SC 
Sbjct: 288  EDYGNKWSMSAMLRYLKQEGRDTTALMAHVEDLIIKTIISAELAIATACKTFVPHRSSCF 347

Query: 888  ELFGFDIMLDENLKPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNLAGFVLPNAEDIIS 947
            EL+GFD+++D  LKPW+LEVN+SPSL   +PLD+ IK  MI D+  + GFV  +     S
Sbjct: 348  ELYGFDVLIDSTLKPWLLEVNLSPSLACDAPLDLKIKASMISDMFTVVGFVCQDPAQRAS 407

Query: 948  SPS--SCSSSTTSLPTSPGDKCRMAPEHVTAQKMKKAYYLTQKIPDQDFYASVLDVLTPD 1005
            +        S+   P     +CR  P   +  +MK      ++        SVL  L+ +
Sbjct: 408  TRPIYPTFESSRRNPFQKPQRCR--PLSASDAEMKNLVGSAREKGPGKLGGSVLG-LSME 464

Query: 1006 DVRILVEMEDEFSRRGQFERIFPS 1029
            ++++L  +++E  RRG F RIFP+
Sbjct: 465  EIKVLRRVKEENDRRGGFIRIFPT 488


>gi|195963418 tubulin tyrosine ligase-like family, member 6 isoform
           1 [Homo sapiens]
          Length = 891

 Score =  221 bits (563), Expect = 3e-57
 Identities = 144/415 (34%), Positives = 212/415 (51%), Gaps = 46/415 (11%)

Query: 527 ENEEEEGDSECSSLSAVSPSESVAMISRSCMEILTKPLSNHEKVVRPALIYSLFPNVPPT 586
           EN EE+GDS     S   P E+VA+                            F    P 
Sbjct: 61  ENSEEKGDS-----SKEDPKETVALA---------------------------FVRENPG 88

Query: 587 IYFGTRDERVEKLPWEQRKLLRWKMSTVTPNIVKQTIGRSHFKISKRNDDWLGCWGHHMK 646
              G ++ + +     ++K L   +S+     V++   +  F+    +DDW   W  +  
Sbjct: 89  AQNGLQNAQQQGKKKRKKKRLVINLSSCRYESVRRAAQQYGFREGGEDDDWTLYWTDYSV 148

Query: 647 S-PSFRSIREHQKLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQDAKL 705
           S      ++ +QK+NHFPG  +I RKD L RN+SRM   F  K+F FFP+++ LP D   
Sbjct: 149 SLERVMEMKSYQKINHFPGMSEICRKDLLARNMSRMLKMF-PKDFRFFPRTWCLPADWGD 207

Query: 706 LRKAWESSSRQKWIVKPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKFDL 765
           L+    S   + +I KP +  +G GI +     ++     ++ Q Y+ KP++I G KFDL
Sbjct: 208 LQTYSRSRKNKTYICKPDSGCQGKGIFITRTVKEIKPGEDMICQLYISKPFIIDGFKFDL 267

Query: 766 RIYVYVTSYDPLRIYLFSDGLVRFASCKYS-PSMKSLGNKFMHLTNYSVNKKNAEYQANA 824
           RIYV VTS DPLRI+++++GL RFA+  YS P   +L +  MHLTNYS+NK ++ +  +A
Sbjct: 268 RIYVLVTSCDPLRIFVYNEGLARFATTSYSRPCTDNLDDICMHLTNYSINKHSSNFSRDA 327

Query: 825 DEMACQGHKWALKALWNYLSQKGVNSDAIWEKIKDVVVKTIISSEP-----YVTSLLKMY 879
                 G K  L     YL     N + IW  I+DV++KT+IS+ P     Y T      
Sbjct: 328 H----SGSKRKLSTFSAYLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHT 383

Query: 880 VRRPYSCHELFGFDIMLDENLKPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNL 934
           +    +C E+ GFDI+LD  LKPW+LEVN SPS  + S LD  +K  ++ D L L
Sbjct: 384 LNS--ACFEILGFDILLDHKLKPWLLEVNHSPSFSTDSRLDKEVKDGLLYDTLVL 436


>gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo
           sapiens]
          Length = 592

 Score =  202 bits (514), Expect = 2e-51
 Identities = 120/345 (34%), Positives = 192/345 (55%), Gaps = 30/345 (8%)

Query: 605 KLLRWKMSTVTPNIVKQTI---GRSHFKISKRN-DDWLGCWGHHMKSPSFR-----SIRE 655
           K L +++   TP +V+  +   G + F   ++N +DW   W    ++ SFR     S++ 
Sbjct: 85  KPLVFRVDETTPAVVQSVLLERGWNKFDKQEQNAEDWNLYW----RTSSFRMTEHNSVKP 140

Query: 656 HQKLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQD-AKLLRKAWES-- 712
            Q+LNH PG+ ++ RKD L ++L  M+  +G   + F P +F++P D  K + + ++   
Sbjct: 141 WQQLNHHPGTTKLTRKDCLAKHLKHMRRMYGTSLYQFIPLTFVMPNDYTKFVAEYFQERQ 200

Query: 713 ---SSRQKWIVKPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKFDLRIYV 769
              +    WI KP   +RG GI +   +         +VQ+Y+  P LI   K DLRIYV
Sbjct: 201 MLGTKHSYWICKPAELSRGRGILIFSDFKDFIFDDMYIVQKYISNPLLIGRYKCDLRIYV 260

Query: 770 YVTSYDPLRIYLFSDGLVRFASCKYSPSMKSLGNKFMHLTNYSVNKKNAEYQANADEMAC 829
            VT + PL IY++ +GLVRFA+ K+   + +L N + HLTN S+NK  A Y+    E+  
Sbjct: 261 CVTGFKPLTIYVYQEGLVRFATEKF--DLSNLQNNYAHLTNSSINKSGASYE-KIKEVIG 317

Query: 830 QGHKWALKALWNYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTSLLKMYVRRPYSCHEL 889
            G KW L   ++YL    V+   +W+KI  +V+ TI++  P V            +C EL
Sbjct: 318 HGCKWTLSRFFSYLRSWDVDDLLLWKKIHRMVILTILAIAPSVPFAA--------NCFEL 369

Query: 890 FGFDIMLDENLKPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNL 934
           FGFDI++D+NLKPW+LEVN SP+L      D+ +K +++ D+++L
Sbjct: 370 FGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDL 414


>gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo
           sapiens]
          Length = 887

 Score =  201 bits (510), Expect = 5e-51
 Identities = 116/295 (39%), Positives = 177/295 (60%), Gaps = 19/295 (6%)

Query: 653 IREHQKLNHFPGSFQIGRKDRLWRNLSRM-QSRFGKKEFSFFPQSFILP----QDAKLLR 707
           ++ +Q++NHFPG  +I RKD L RN+++M +SR    +++F P+++I P    Q    ++
Sbjct: 89  LQNYQRINHFPGMGEICRKDFLARNMTKMIKSR--PLDYTFVPRTWIFPAEYTQFQNYVK 146

Query: 708 KAWESSSRQKWIVKPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKFDLRI 767
           +  +   ++ +IVKP   A G GI +I    +LP +  L+VQ Y+ KP+L+ G KFDLRI
Sbjct: 147 ELKKKRKQKTFIVKPANGAMGHGISLIRNGDKLPSQDHLIVQEYIEKPFLMEGYKFDLRI 206

Query: 768 YVYVTSYDPLRIYLFSDGLVRFASCKYSPSMKS-LGNKFMHLTNYSVNKKNAEYQANADE 826
           Y+ VTS DPL+I+L+ DGLVR  + KY P  +S L   +MHLTNYSVNK N  ++   DE
Sbjct: 207 YILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFE--RDE 264

Query: 827 MACQGHKWALKALWNYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTSLLKMYVRRPYS- 885
              +G K ++K    +L     +    W  I ++VVKT+I +EP+V    +M   RP   
Sbjct: 265 TENKGSKRSIKWFTEFLQANQHDVAKFWSDISELVVKTLIVAEPHVLHAYRMC--RPGQP 322

Query: 886 ------CHELFGFDIMLDENLKPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNL 934
                 C E+ GFDI+LD  LKPW+LE+N +PS  +   +D  +K  ++ + L L
Sbjct: 323 PGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKL 377


>gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo
           sapiens]
          Length = 459

 Score =  197 bits (502), Expect = 4e-50
 Identities = 138/446 (30%), Positives = 216/446 (48%), Gaps = 34/446 (7%)

Query: 501 LQPDQAETEDTEEELVDGLEDCCSRDENEEEEGDSECSSLSAVSPSESVAMISRSCMEIL 560
           ++P    T ++EE+ V             EE+   +C      +PS S     ++ ++  
Sbjct: 1   MEPSTCRTMESEEDYV-------------EEKESEKCVKEGVTNPSNSS---QQALLKAD 44

Query: 561 TKPLSNHEKVVRPALIYSLFPNVPPTIYFGTRDERVEKLPWEQRKLLRWKMSTVTPNIVK 620
            K L N   V  P +   +   V   +  G  +    K    +R+ L   ++      V+
Sbjct: 45  YKALKNG--VPSPIMATKIPKKVIAPVDTGDLEAGRRKRR-RKRRSLAINLTNCKYESVR 101

Query: 621 QTIGRSHFKISKRNDDWLGCWGHHMKS-PSFRSIREHQKLNHFPGSFQIGRKDRLWRNLS 679
           +       K    +++W   W     S      ++  QK+NHFPG  +I RKD L RNL+
Sbjct: 102 RAAQMCGLKEVGEDEEWTLYWTDCAVSLERVMDMKRFQKINHFPGMTEICRKDLLARNLN 161

Query: 680 RMQSRFGKKEFSFFPQSFILPQDAKLLRKAWESSSRQKWIVKPPASARGIGIQVIHKWSQ 739
           RM   +   E++ FP+++ LP D    +        + +I KP +  +G GI +     +
Sbjct: 162 RMYKLY-PSEYNIFPRTWCLPADYGDFQSYGRQRKARTYICKPDSGCQGRGIFITRNPRE 220

Query: 740 LPKRRPLLVQRYLHKPYLISGSKFDLRIYVYVTSYDPLRIYLFSDGLVRFASCKY-SPSM 798
           +     ++ Q+Y+ KP LI G KFD+R+YV +TS DPLRI+ + +GL RFA+  Y  PS 
Sbjct: 221 IKPGEHMICQQYISKPLLIDGFKFDMRVYVLITSCDPLRIFTYEEGLARFATTPYMEPSH 280

Query: 799 KSLGNKFMHLTNYSVNKKNAEYQANADEMACQGHKWALKALWNYLSQKGVNSDAIWEKIK 858
            +L N  MHLTNY++NK N  +  +       G K  L  L  +L +   N   +W  I+
Sbjct: 281 NNLDNVCMHLTNYAINKHNENFVRD----GAVGSKRKLSTLNIWLQEHSYNPGELWGDIE 336

Query: 859 DVVVKTIISSEP-----YVTSLLKMYVRRPYSCHELFGFDIMLDENLKPWVLEVNISPSL 913
           D+++KTIIS+       Y T   +       +C E+ GFDI+LD  LKPW+LEVN SPS 
Sbjct: 337 DIIIKTIISAHSVLRHNYRTCFPQYLNGGTCACFEILGFDILLDHKLKPWLLEVNHSPSF 396

Query: 914 HSSSPLDISIKGQMIRD---LLNLAG 936
            + S LD  +K  ++ D   L+NL G
Sbjct: 397 TTDSCLDQEVKDALLCDAMTLVNLRG 422


>gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo
           sapiens]
          Length = 423

 Score =  177 bits (450), Expect = 4e-44
 Identities = 111/350 (31%), Positives = 178/350 (50%), Gaps = 60/350 (17%)

Query: 634 NDDWLGCWGHHMKSPSFRSI---------REHQKLNHFPGSFQIGRKDRLWRNLSRMQSR 684
           N+DW   W   M   + R++          + Q +NHFP  +++ RKD + +N+ R +  
Sbjct: 31  NEDWNFYW---MSVQTIRNVFSVEAGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKE 87

Query: 685 FGKKE--------------FSFFPQSFILPQDAKLLRKAWESSSRQKWIVKPPASARGIG 730
             K+                 F P +++LP D  L  + +  S    WI+KP   A+G G
Sbjct: 88  LEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKG 147

Query: 731 IQVIHKWSQLPK---------------RRPLLVQRYLHKPYLISGSKFDLRIYVYVTSYD 775
           I +I+K SQ+ K               +   ++  Y++ P LI G KFDLR+YV V++Y 
Sbjct: 148 IFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLIGGRKFDLRLYVLVSTYR 207

Query: 776 PLRIYLFSDGLVRFASCKYSPSMKSLGNKFMHLTNYSVNKKNAEYQANADEMACQGHKWA 835
           PLR Y++  G  RF + KY+PS   L N F+HLTN ++ K   +Y          G KW 
Sbjct: 208 PLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYN------HIHGGKWT 261

Query: 836 LKALWNYL-SQKGVN-SDAIWEKIKDVVVKTIISSEPYVTSLLKMYVRRPYSCHELFGFD 893
           +  L  YL S +G   +  ++++I  ++V+++ +  P + +           C E +G+D
Sbjct: 262 VSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNN--------DKHCFECYGYD 313

Query: 894 IMLDENLKPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNLAGFVLPNAE 943
           I++D+ LKPW++EVN SPSL SS+  D  +K  +I D LN+A   +PN E
Sbjct: 314 IIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIA---VPNGE 360


>gi|212720861 tubulin tyrosine ligase-like family, member 11 a [Homo
           sapiens]
          Length = 800

 Score =  164 bits (415), Expect = 5e-40
 Identities = 112/306 (36%), Positives = 169/306 (55%), Gaps = 32/306 (10%)

Query: 658 KLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQDAKL------LRKAWE 711
           ++N FPG  ++ RK  L R +  MQ+ F  +E++F+P+S+ILP + +L      + K  +
Sbjct: 271 QVNKFPGMTEMVRKITLSRAVRTMQNLF-PEEYNFYPRSWILPDEFQLFVAQVQMVKDDD 329

Query: 712 SSSRQKWIVKPPASARGIGIQVIHKWSQLP-----KRRPLLVQRYLHKPYLISGSKFDLR 766
            S +  +IVKP    +G GI +I   S +      + RP +VQ Y+ KP LI   KFD+R
Sbjct: 330 PSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRPAVVQEYICKPLLIDKLKFDIR 389

Query: 767 IYVYVTSYDPLRIYLFSDGLVRFASCKY-SPSMKSLGNKFMHLTNYSVNKKNAEYQANAD 825
           +YV + S DPL IY+  DGL RF +  Y  P+ K+L   FMHLTNYS+N  +  +  +  
Sbjct: 390 LYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGNFIHS-- 447

Query: 826 EMACQGHKWALKALWNYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTSLLKMYV---RR 882
           + A  G K    ++   LS KGV+   +W  I  VV+KT+I+  P +    +  +   R 
Sbjct: 448 DSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVIALTPELKVFYQSDIPTGRP 507

Query: 883 PYSCHELFGFDIMLDENLKPWVLEVNISPSL-----HSSSP---------LDISIKGQMI 928
             +C ++ GFDI+L +NLKP +LEVN +PS+     H  SP         +D  +K  +I
Sbjct: 508 GPTCFQILGFDILLMKNLKPILLEVNANPSMRIEHEHELSPGVFENVPSLVDEEVKVAVI 567

Query: 929 RDLLNL 934
           RD L L
Sbjct: 568 RDTLRL 573


>gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Homo
           sapiens]
          Length = 538

 Score =  132 bits (333), Expect = 2e-30
 Identities = 85/225 (37%), Positives = 128/225 (56%), Gaps = 15/225 (6%)

Query: 658 KLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQDAKL------LRKAWE 711
           ++N FPG  ++ RK  L R +  MQ+ F  +E++F+P+S+ILP + +L      + K  +
Sbjct: 271 QVNKFPGMTEMVRKITLSRAVRTMQNLF-PEEYNFYPRSWILPDEFQLFVAQVQMVKDDD 329

Query: 712 SSSRQKWIVKPPASARGIGIQVIHKWSQLP-----KRRPLLVQRYLHKPYLISGSKFDLR 766
            S +  +IVKP    +G GI +I   S +      + RP +VQ Y+ KP LI   KFD+R
Sbjct: 330 PSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRPAVVQEYICKPLLIDKLKFDIR 389

Query: 767 IYVYVTSYDPLRIYLFSDGLVRFASCKY-SPSMKSLGNKFMHLTNYSVNKKNAEYQANAD 825
           +YV + S DPL IY+  DGL RF +  Y  P+ K+L   FMHLTNYS+N  +  +  +  
Sbjct: 390 LYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGNFIHS-- 447

Query: 826 EMACQGHKWALKALWNYLSQKGVNSDAIWEKIKDVVVKTIISSEP 870
           + A  G K    ++   LS KGV+   +W  I  VV+KT+I+  P
Sbjct: 448 DSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVIALTP 492


>gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo
           sapiens]
          Length = 439

 Score =  132 bits (333), Expect = 2e-30
 Identities = 92/305 (30%), Positives = 152/305 (49%), Gaps = 56/305 (18%)

Query: 655 EHQKLNHFPGSFQIGRKDRLWRNLSRMQSRF----GKKEFS---FFPQSFILPQDAKLLR 707
           EH +++HF   +++ RK+ + +NL R + +     GK E +   FFP++F +P +  L  
Sbjct: 94  EHVRISHFRNHYELTRKNYMVKNLKRFRKQLEREAGKLEAAKCDFFPKTFEMPCEYHLFV 153

Query: 708 KAWESSSRQKWIVKPPASARGIGIQVIHKWSQLPKRRP----------------LLVQRY 751
           + +  +    WI+KP A ++G GI +  +   +   R                  + QRY
Sbjct: 154 EEFRKNPGITWIMKPVARSQGKGIFLFRRLKDIVDWRKDTRSSDDQKDDIPVENYVAQRY 213

Query: 752 LHKPYLISGSKFDLRIYVYVTSYDPLRIYLFSDGLVRFASCKYSPSMKSLGNKFMHLTNY 811
           +  PYLI G KFDLR+YV V S               FA C      +    + +HLTN 
Sbjct: 214 IENPYLIGGRKFDLRVYVLVMSV--------------FAECLLWSGHR---RQDVHLTNV 256

Query: 812 SVNKKNAEYQANADEMACQGHKWALKALWNYLSQK-GVNS-DAIWEKIKDVVVKTIISSE 869
           +V K + +Y         +G KW L+    YL+ K G  + + ++  I ++ VK++ S +
Sbjct: 257 AVQKTSPDYHPK------KGCKWTLQRFRQYLASKHGPEAVETLFRDIDNIFVKSLQSVQ 310

Query: 870 PYVTSLLKMYVRRPYSCHELFGFDIMLDENLKPWVLEVNISPSLHSSSPLDISIKGQMIR 929
             + S           C EL+G+DI++D++LKPW+LEVN SPSL +SS  D  +K  ++ 
Sbjct: 311 KVIIS--------DKHCFELYGYDILIDQDLKPWLLEVNASPSLTASSQEDYELKTCLLE 362

Query: 930 DLLNL 934
           D L++
Sbjct: 363 DTLHV 367


>gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo
           sapiens]
          Length = 772

 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 66/233 (28%), Positives = 119/233 (51%), Gaps = 25/233 (10%)

Query: 715 RQKWIVKPPASARGIGIQVIHKWSQLPKR---RPLL-------VQRYLHKPYLISGSKFD 764
           R  WIVKP A +RG GI  +    ++ K     P++       VQ+Y+ +P LI G+KFD
Sbjct: 277 RNIWIVKPGAKSRGRGIMCMDHLEEMLKLVNGNPVVMKDGKWVVQKYIERPLLIFGTKFD 336

Query: 765 LRIYVYVTSYDPLRIYLFSDGLVRFASCKYSPSMKSLGNKFMHLTNYSVNKKNAEYQANA 824
           LR +  VT ++PL ++ + D  +RF++  +  S+K+L N  +HL N S+ +K+ E   + 
Sbjct: 337 LRQWFLVTDWNPLTVWFYRDSYIRFSTQPF--SLKNLDNS-VHLCNNSI-QKHLENSCHR 392

Query: 825 DEMACQGHKWALKALWNYLSQKGVN---SDAIWEKIKDVVVKTIISSEPYVTSLLKMYVR 881
             +    + W+ +    +L + G     S  I   +KD V+  + +S+  V      +  
Sbjct: 393 HPLLPPDNMWSSQRFQAHLQEMGAPNAWSTIIVPGMKDAVIHALQTSQDTVQCRKASF-- 450

Query: 882 RPYSCHELFGFDIMLDENLKPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNL 934
                 EL+G D +  E+ +PW++E+N SP++  S+ +   +   +  D L +
Sbjct: 451 ------ELYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRV 497


>gi|194239681 tubulin tyrosine ligase-like family, member 10 isoform
           1 [Homo sapiens]
          Length = 673

 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 93/347 (26%), Positives = 151/347 (43%), Gaps = 79/347 (22%)

Query: 692 FFPQSFILPQDAKLLRKAWES--SSRQKWIVKPPASARGIGIQVIHKWSQL--------- 740
           FFP+++ L  D K  R+A+ +     Q WI KP AS +G GI ++    ++         
Sbjct: 284 FFPETYRL--DLKHEREAFFTLFDETQIWICKPTASNQGKGIFLLRNQEEVAALQAKTRS 341

Query: 741 ----------PKRRPL--LVQRYLHKPYLISGSKFDLRIYVYVTSYDPLRIYLFSDGLVR 788
                     P R P   +VQRY+  P L+ G KFD+R Y+ +    P  I+ F  G  R
Sbjct: 342 MEDDPIHHKTPFRGPQARVVQRYIQNPLLVDGRKFDVRSYLLIACTTPYMIF-FGHGYAR 400

Query: 789 FASCKYSPSMKSLGNKFMHLTNYSVNKKNAEYQANADEMACQGHKWALKALWNYLSQ--- 845
                Y P    LG    HLTN  + KK+  Y    +        W+++ L  Y+S    
Sbjct: 401 LTLSLYDPHSSDLGG---HLTNQFMQKKSPLYMLLKEHTV-----WSMEHLNRYISDTFW 452

Query: 846 --KGVNSDAIWEKIK----DVVVKTIISSEPYVTSLLKMYVRRPYSCHELFGFDIMLDEN 899
             +G+  D ++  +K     ++    ++++P +   L  +        +L G D ++D+N
Sbjct: 453 KARGLAKDWVFTTLKKRMQQIMAHCFLAAKPKLDCKLGYF--------DLIGCDFLIDDN 504

Query: 900 LKPWVLEVNISPSLHSS-------------SPLDI-------SIKGQMIRDLLNLAGFVL 939
            K W+LE+N +P+LH++               LD+       S++GQ +  LL+   FVL
Sbjct: 505 FKVWLLEMNSNPALHTNCEVLKEVIPGVVIETLDLVLETFRKSLRGQKMLPLLSQRRFVL 564

Query: 940 PNAEDIISSP---SSCS-SSTTSLPT----SPGDKCRMAPEHVTAQK 978
            +  +    P    SCS      LPT    S G     AP+   A++
Sbjct: 565 LHNGEADPRPHLGGSCSLRRWPPLPTRQAKSSGPPMPHAPDQPGARR 611


>gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo
           sapiens]
          Length = 834

 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 59/235 (25%), Positives = 114/235 (48%), Gaps = 23/235 (9%)

Query: 715 RQKWIVKPPASARGIG--------------IQVIHKWSQLPKRRPLLVQRYLHKPYLISG 760
           R  WI+KP A +RG G              +++      L +    +VQ+Y+  P LI  
Sbjct: 328 RNIWIIKPAAKSRGRGESPDIVCMDRVEEILELAAADHPLSRDNKWVVQKYIETPLLICD 387

Query: 761 SKFDLRIYVYVTSYDPLRIYLFSDGLVRFASCKYSPSMKSLGNKFMHLTNYSVNKKNAEY 820
           +KFD+R +  VT ++PL I+ + +  +RF++ ++S       +  +HL N +V +K  + 
Sbjct: 388 TKFDIRQWFLVTDWNPLTIWFYKESYLRFSTQRFSLDKL---DSAIHLCNNAV-QKYLKN 443

Query: 821 QANADEMACQGHKWALKALWNYLSQKGVNSDAIWEKIKDVVVKTIISSEPYVTSLLKMYV 880
                 +    + W       YL ++G    A+W  +    +K  I+   +   + + +V
Sbjct: 444 DVGRSPLLPAHNMWTSTRFQEYLQRQG--RGAVWGSVIYPSMKKAIA---HAMKVAQDHV 498

Query: 881 RRPYSCHELFGFDIMLDENLKPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNLA 935
               +  EL+G D +L  + +PW++E+N SP++H S+P+   +  Q+  D + +A
Sbjct: 499 EPRKNSFELYGADFVLGRDFRPWLIEINSSPTMHPSTPVTAQLCAQVQEDTIKVA 553


>gi|24308516 tubulin tyrosine ligase [Homo sapiens]
          Length = 377

 Score = 88.2 bits (217), Expect = 4e-17
 Identities = 74/251 (29%), Positives = 124/251 (49%), Gaps = 27/251 (10%)

Query: 711 ESSSRQKWIVKPPASARGIGIQVIHKWSQL-----PKRRPLLVQRYLHKPYLISGS--KF 763
           E      WI K  A A+G GI +  + S+L      + +  ++Q+YL  P L+     KF
Sbjct: 140 EDGEGNVWIAKSSAGAKGEGILISSEASELLDFIDNQGQVHVIQKYLEHPLLLEPGHRKF 199

Query: 764 DLRIYVYVTSYDPLRIYLFSDGLVRFASCKYSPSMKSLGNKFMHLTNYSVNKKNAEYQAN 823
           D+R +V V       IYL+ +G++R AS  Y   + +  +K  HLTN+ + K   EY  N
Sbjct: 200 DIRSWVLVDHQ--YNIYLYREGVLRTASEPYH--VDNFQDKTCHLTNHCIQK---EYSKN 252

Query: 824 ADEMACQGHKWALKALWNYLSQKGVN---SDAIWEKIKDVVVKTIISSEPYVTSLLKMYV 880
             +   +G++   K    YL+   +N     +I  +IK ++   ++S EP +++      
Sbjct: 253 YGKYE-EGNEMFFKEFNQYLTS-ALNITLESSILLQIKHIIRNCLLSVEPAISTK----- 305

Query: 881 RRPYSCHELFGFDIMLDENLKPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNLAGFVLP 940
             PY   +LFGFD M+DE LK W++EVN +P+       ++    Q I D+   + F  P
Sbjct: 306 HLPYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELC---QGIVDIAISSVFPPP 362

Query: 941 NAEDIISSPSS 951
           + E   + P++
Sbjct: 363 DVEQPQTQPAA 373


>gi|195963416 tubulin tyrosine ligase-like family, member 6 isoform
           2 [Homo sapiens]
          Length = 584

 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 41/98 (41%), Positives = 56/98 (57%), Gaps = 7/98 (7%)

Query: 842 YLSQKGVNSDAIWEKIKDVVVKTIISSEP-----YVTSLLKMYVRRPYSCHELFGFDIML 896
           YL     N + IW  I+DV++KT+IS+ P     Y T      +    +C E+ GFDI+L
Sbjct: 34  YLEDHSYNVEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLNS--ACFEILGFDILL 91

Query: 897 DENLKPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNL 934
           D  LKPW+LEVN SPS  + S LD  +K  ++ D L L
Sbjct: 92  DHKLKPWLLEVNHSPSFSTDSRLDKEVKDGLLYDTLVL 129


>gi|194239678 tubulin tyrosine ligase-like family, member 10 isoform
           2 [Homo sapiens]
          Length = 404

 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 56/195 (28%), Positives = 86/195 (44%), Gaps = 39/195 (20%)

Query: 692 FFPQSFILPQDAKLLRKAWES--SSRQKWIVKPPASARGIGIQVIHKWSQL--------- 740
           FFP+++ L  D K  R+A+ +     Q WI KP AS +G GI ++    ++         
Sbjct: 211 FFPETYRL--DLKHEREAFFTLFDETQIWICKPTASNQGKGIFLLRNQEEVAALQAKTRS 268

Query: 741 ----------PKRRPL--LVQRYLHKPYLISGSKFDLRIYVYVTSYDPLRIYLFSDGLVR 788
                     P R P   +VQRY+  P L+ G KFD+R Y+ +    P  I+ F  G  R
Sbjct: 269 MEDDPIHHKTPFRGPQARVVQRYIQNPLLVDGRKFDVRSYLLIACTTPYMIF-FGHGYAR 327

Query: 789 FASCKYSPSMKSLGNKFMHLTNYSVNKKNAEYQANADEMACQGHKWALKALWNYLSQ--- 845
                Y P    LG    HLTN  + KK+  Y    +        W+++ L  Y+S    
Sbjct: 328 LTLSLYDPHSSDLGG---HLTNQFMQKKSPLYMLLKEHTV-----WSMEHLNRYISDTFW 379

Query: 846 --KGVNSDAIWEKIK 858
             +G+  D ++  +K
Sbjct: 380 KARGLAKDWVFTTLK 394


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 36/113 (31%), Positives = 46/113 (40%), Gaps = 5/113 (4%)

Query: 476  QSEKERPEEARELDSSDRDISSATDLQPDQAETEDTEEELVDGLEDC---CSRDENEEEE 532
            +S  E+ EE  E D  D D   A D    + E  D E+E  D    C      D   +  
Sbjct: 971  ESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDST 1030

Query: 533  GDSECSSLSAVSPSESVAMISRSCMEILTKPLSNHEKVVRPALIYSLFPNVPP 585
             DSE SS S+ S S S +  S S          + E+  RPA + S  P  PP
Sbjct: 1031 SDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASP--PP 1081


>gi|11056036 tubulin tyrosine ligase-like family, member 12 [Homo
           sapiens]
          Length = 644

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 59/252 (23%), Positives = 97/252 (38%), Gaps = 21/252 (8%)

Query: 578 SLFPNVPPTIYFGTRDERVEKLPWEQRKLLR-----WKMSTVTPNIVKQ-TIGRSHFKIS 631
           S  P  P   Y    +E  EKLP +   ++      +K+ T    +    T  R     S
Sbjct: 269 SCTPEPPAEHYQAILEENKEKLPLDINPVVHPHGHIFKVYTDVQQVASSLTHPRFTLTQS 328

Query: 632 KRNDDWLGCWGHHMKSPSFRSIREHQKLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFS 691
           + + D L  + H          R    LN FP    +  KD L    S  +   G +   
Sbjct: 329 EADADILFNFSHFKDYRKLSQERPGVLLNQFPCENLLTVKDCL---ASIARRAGGPEGPP 385

Query: 692 FFPQSFIL----PQDAKLLRKAWESSSRQKWIVKPPASARGIGIQVIHKWSQLPKRR--- 744
           + P++F L    PQ     ++         WI KP   AR +   V      + + R   
Sbjct: 386 WLPRTFNLRTELPQFVSYFQQRERWGEDNHWICKPWNLARSLDTHVTKSLHSIIRHREST 445

Query: 745 PLLVQRYLHKPYL-----ISGSKFDLRIYVYVTSYDPLRIYLFSDGLVRFASCKYSPSMK 799
           P +V +Y+  P L     +   KFD+R  V + S  PLR++++    +RF++  ++ +  
Sbjct: 446 PKVVSKYIESPVLFLREDVGKVKFDIRYIVLLRSVRPLRLFVYDVFWLRFSNRAFALNDL 505

Query: 800 SLGNKFMHLTNY 811
               K   + NY
Sbjct: 506 DDYEKHFTVMNY 517


>gi|19923844 coiled-coil domain containing 82 [Homo sapiens]
          Length = 544

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 30/124 (24%), Positives = 61/124 (49%), Gaps = 2/124 (1%)

Query: 476 QSEKERPEEARELDSSDRDISSATDLQPDQAETEDTEEELVDGLEDCCSRDENEEEEGDS 535
           Q  ++R    R+ + S+++   ++D + D+ E ED  E   DG +        ++EEGD 
Sbjct: 249 QRSRQRRSSGRDFEDSEKESCPSSD-EVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDE 307

Query: 536 ECSSLSAVSPSES-VAMISRSCMEILTKPLSNHEKVVRPALIYSLFPNVPPTIYFGTRDE 594
           E  +      + S + ++ ++ +   +   ++ E+VV+  LI +L  +   T+Y GTR +
Sbjct: 308 ENKNQQGEKLTTSQLKLVKQNSLYSFSDHYTHFERVVKALLINALDESFLGTLYDGTRQK 367

Query: 595 RVEK 598
              K
Sbjct: 368 SYAK 371


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 40.8 bits (94), Expect = 0.008
 Identities = 45/158 (28%), Positives = 69/158 (43%), Gaps = 15/158 (9%)

Query: 153  LPVSLTANKATSSMVFSMAQPMASSSTEPYLCLAAAGENPSGKSLASAISGKIPSPLSSS 212
            LPV+  ++ +T          ++S+ST     L     N S  S    +   + SP S+S
Sbjct: 3233 LPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVT--NTSSVSTGDTMPLPVTSPSSAS 3290

Query: 213  YK-----PMLNNNSFMWPNSTPVPLLQTTQGLKPVSPPKIQPVSWHHSGGTGDCAPQPVD 267
                   P+ + +S    ++TPVP+  T+      + P   PV+   S  TGD  P PV 
Sbjct: 3291 TGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPL--PVTDTSSASTGDTTPLPVT 3348

Query: 268  HKVPKSIG-TVPADASAHIAL-STASSHDTSTTSVASS 303
                 S G T P     H+ + S+AS+ DTST  V  +
Sbjct: 3349 SPSSASTGHTTP----LHVTIPSSASTGDTSTLPVTGA 3382



 Score = 38.5 bits (88), Expect = 0.039
 Identities = 75/316 (23%), Positives = 121/316 (38%), Gaps = 26/316 (8%)

Query: 2    ASAGTQHYSIGLRQKNSFKQSGPSGTVPATPPEKPSEGRVWPQAHQQVKPIWKLEKKQVE 61
            AS+G++  S G    +S   SG SGT P+      + G     +    +     +    E
Sbjct: 791  ASSGSRTTSAGTATPSS---SGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQST-TE 846

Query: 62   TLSAGLGPGLLGVPPQPAYFFCPSTLCSSGTTAVIAGHSSSCYLHSLPDLF-NSTLLYRR 120
             LSA    G + V    A    P T   + + A  AG  +     + P      T    R
Sbjct: 847  LLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISR 906

Query: 121  SSYRQKPYQQLESFCLRSSPSEKSPFSLPQKSLPVSLTANKATSSMVFSMAQPMASSSTE 180
             +  Q+      S  +  +      FS    + P S+T+   TS    +      S S +
Sbjct: 907  MAQTQRTRTSRGSDTISLASQATDTFSTVPPT-PPSITSTGLTSPQTETHTLS-PSGSGK 964

Query: 181  PYLCLAAAGENPSGKSLASAISGKIPSPL----SSSYK-------PMLNNNSFMWPNSTP 229
             +     +   P   + AS+ S    +PL    +SS         P+ + +S    ++TP
Sbjct: 965  TFTTALISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTP 1024

Query: 230  VPLLQTT-QGLKPVSPPKIQPVSWHHSGGTGDCAPQPVDHKVPKSIGTV-PADASAHIAL 287
            +P+  T+ +    V+P    PV+   S  TGD  P PV      S G V P   +   +L
Sbjct: 1025 LPVTDTSSESTGHVTP---LPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVT---SL 1078

Query: 288  STASSHDTSTTSVASS 303
            S+AS+ DT+   V  +
Sbjct: 1079 SSASTGDTTPLPVTDT 1094



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 48/172 (27%), Positives = 75/172 (43%), Gaps = 20/172 (11%)

Query: 138  SSPSEKSPFSLPQKSLPVSLTANKATSSMVFSMAQPMASSSTEPYLCLAAAGENPSGKSL 197
            SS S     SLP  SL  + T +  T+ +  +     +S  T P L +  A   P+G + 
Sbjct: 1911 SSVSTGHATSLPVTSLSSASTGD--TTPLPVTSPSSASSGHTTP-LPVTDASSVPTGHAT 1967

Query: 198  ------ASAISGKIPSPLSSSYKPMLNNNSFMWPNSTPVPLLQTTQGLKPVSPPKIQPVS 251
                  AS++S    +PL     P+ + +S    ++TP+P+  T+      + P   PV+
Sbjct: 1968 SLPVTDASSVSTGHATPL-----PVTDASSVSTGHATPLPVTDTSSVSTGQATPL--PVT 2020

Query: 252  WHHSGGTGDCAPQPVDHKVPKSIG-TVPADASAHIALSTASSHDTSTTSVAS 302
               S  TGD  P PV      S G   P   +   +LS+ S+ DT+   V S
Sbjct: 2021 SLSSASTGDTTPLPVTDTSSASTGQDTPLPVT---SLSSVSTGDTTPLPVTS 2069



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 38/154 (24%), Positives = 65/154 (42%), Gaps = 7/154 (4%)

Query: 153  LPVSLTANKATSSMVFSMAQPMASSSTEPYLCLAAAGENPSGKSLASAISGKIPSPLSSS 212
            LPV+ T++ +T           +S ST     L     + +    A+ +     S +S+ 
Sbjct: 3809 LPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTDTSSVSTG 3868

Query: 213  YK---PMLNNNSFMWPNSTPVPLLQTTQGLKPVSPPKIQPVSWHHSGGTGDCAPQPVDHK 269
            +    P+ + +S    ++TP+P+   +      + P   PV+   S  TGD  P PV + 
Sbjct: 3869 HATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPV--PVTSTSSASTGDTTPLPVTN- 3925

Query: 270  VPKSIGTVPADASAHIALSTASSHDTSTTSVASS 303
               S+ T  A      + S+AS  DTST  V  +
Sbjct: 3926 -ASSLSTGHATPLHVTSPSSASRGDTSTLPVTDA 3958



 Score = 35.0 bits (79), Expect = 0.43
 Identities = 43/167 (25%), Positives = 73/167 (43%), Gaps = 30/167 (17%)

Query: 153  LPVSLTANKATSSMVFSMAQPMASSSTEPYLCLAAAGEN-PSGKSLASAISGKIPSPLSS 211
            LPV+  ++ +T     +M  P+ S S+      A+ G+  P   + AS++S    +PL  
Sbjct: 1521 LPVTSLSSASTGD---TMPLPVTSPSS------ASTGDTTPLPVTDASSVSTGHTTPL-- 1569

Query: 212  SYKPMLNNNSFMWPNSTPVPLLQTTQGLK------PVSPPKIQ--------PVSWHHSGG 257
               P+ + +S    ++TP+P+  T+   K      PV+ P           PV+   S  
Sbjct: 1570 ---PVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSAS 1626

Query: 258  TGDCAPQPVDHKVPKSIG-TVPADASAHIALSTASSHDTSTTSVASS 303
            TGD  P PV +    S G   P   ++  + ST  +     TS +S+
Sbjct: 1627 TGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSA 1673



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 37/151 (24%), Positives = 57/151 (37%), Gaps = 17/151 (11%)

Query: 152  SLPVSLTANKATSSMVFSMAQPMASSSTEPYLCLAAAGENPSGKSLASAISGKIPSPLSS 211
            SLPV+ T++ +T           +S+ST     L     + +    A+ +    PS  S+
Sbjct: 2160 SLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPLPVTSPSSAST 2219

Query: 212  SYKPMLNNNSFMWPNSTPVPLLQTTQGLKPVSPPKIQPVSWHHSGGTGDCAPQPVDHKVP 271
             +                +PLL T             PV+   S  TGD  P PV     
Sbjct: 2220 GHA---------------IPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTD--A 2262

Query: 272  KSIGTVPADASAHIALSTASSHDTSTTSVAS 302
             S+ T  A +    +LS+ S+ DT+   V S
Sbjct: 2263 SSVSTGHATSLPVTSLSSVSTGDTTPLPVTS 2293



 Score = 32.3 bits (72), Expect = 2.8
 Identities = 47/227 (20%), Positives = 86/227 (37%), Gaps = 26/227 (11%)

Query: 85   STLCSSGTTAV-IAGHSSSCYLHSLPDLFNSTLLYRRSSYRQKPYQQLESFCLRSSPSEK 143
            S++ +  TT + +   SS+   H+ P L   T     S+    P    ++  + +  +  
Sbjct: 1175 SSVSTGDTTPLPVTSPSSASTGHATPLLVTDTS--SASTGHATPLPVTDASSVSTDHATS 1232

Query: 144  SPFSLPQKS-------LPVSLTANKATSSMVFSMAQPMASSSTEPYLCLAAAGENPSGKS 196
             P ++P  +       LPV+ T++ +T      +    +S ST     L     + +   
Sbjct: 1233 LPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTG 1292

Query: 197  LASAISGKIPSPLSSSYKPMLNNNSFMWPNSTPVPLLQTTQGLKPVSPPKIQPVSWHHSG 256
              + +    PS  S+ +             +TP+P+   +      + P   PV+   S 
Sbjct: 1293 HVTPLHVTSPSSASTGH-------------ATPLPVTSLSSASTGDTMPL--PVTSPSSA 1337

Query: 257  GTGDCAPQPVDHKVPKSIG-TVPADASAHIALSTASSHDTSTTSVAS 302
             TGD  P PV      S G T P   +   + ST  +     TS++S
Sbjct: 1338 STGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSS 1384



 Score = 32.3 bits (72), Expect = 2.8
 Identities = 36/155 (23%), Positives = 62/155 (40%), Gaps = 6/155 (3%)

Query: 153  LPVSLTANKATSSMVFSMAQPMASSSTEPYLCLAAAGENPSGKSLASAISGKIPSPLSSS 212
            LPV+ T + +T           +S ST     L     + +    A+++     S  S+ 
Sbjct: 2513 LPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTG 2572

Query: 213  YK---PMLNNNSFMWPNSTPVPLLQTTQGLKPVSPPKIQPVSWHHSGGTGDCAPQPVDHK 269
            +    P+ + +S    ++TP+P+  T       + P   PV+   S  TGD  P PV   
Sbjct: 2573 HATPLPVTSTSSASTGDTTPLPVTDTYSASTGQATPL--PVTDTSSASTGDTTPLPVTDT 2630

Query: 270  VPKSIG-TVPADASAHIALSTASSHDTSTTSVASS 303
               S G   P   +   ++ST  +     TS +S+
Sbjct: 2631 SSASTGHATPLPVTNTSSVSTGHATPLHVTSPSSA 2665



 Score = 31.6 bits (70), Expect = 4.7
 Identities = 48/189 (25%), Positives = 80/189 (42%), Gaps = 25/189 (13%)

Query: 152  SLPVSLTANKATSSMVFSMAQPMASSSTEPYLCLAAAGENPSGKSLASAISGKIPSPLSS 211
            +LPV+ T++ +T           +S+ST            P   +  S++S    +PL  
Sbjct: 3008 ALPVTSTSSASTGDTTPLPVTDTSSAST--------GQATPLPVTSLSSVSTGDTTPL-- 3057

Query: 212  SYKPMLNNNSFMWPNSTPVPLLQTTQGLKPVSPPKIQPVSWHHSGGTGDCAPQPVDHKVP 271
               P+ + +S    ++TP+ +   +      + P   PV+   S  TGD  P PV    P
Sbjct: 3058 ---PVTSPSSASTGHATPLLVTDASSASTGQATPL--PVTSLSSVSTGDTTPLPVTS--P 3110

Query: 272  KSIGTVPADASAHIALSTASSHDTSTTSV--ASSWYNRNNLAMRAEPLSCALDDSSDSQD 329
             S  T  A +      S+AS+ DT++  V   SS Y  +  ++   P++   D SS S  
Sbjct: 3111 SSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSL---PVT---DTSSSSTG 3164

Query: 330  PTKEIRFTE 338
             T  +  TE
Sbjct: 3165 DTTPLLVTE 3173


>gi|239751395 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 38.5 bits (88), Expect = 0.039
 Identities = 62/268 (23%), Positives = 100/268 (37%), Gaps = 31/268 (11%)

Query: 24  PSGTVPATPPEKPSEGRVWPQAHQQVKPIWKLEKKQVETLSAGLGPGLLGVPPQPAYFFC 83
           PS T   TP   P+   + P +   + P   L +    TL+    P L    P       
Sbjct: 60  PSNTPTLTPSSTPT---LTPSSTPTLTPQPILTRSSTPTLTPSSPPTLT---PSNTPTLT 113

Query: 84  PS---TLCSSGTTAVIAGHSSSCYLHSLPDLFNST--LLYRRSSYRQKPYQQLESFCLRS 138
           PS   TL  S T  +    + +    S P L  S+  +L R S+    P  +      RS
Sbjct: 114 PSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSR--PILTRS 171

Query: 139 SPSEKSPFSLPQKSLPVSLTANKATSSMVFSMAQPMASSSTEPYLCLAAAGENPSGKSLA 198
           S    +P S P  +   + T   +++  +   ++P+ + S+ P L        PS + + 
Sbjct: 172 STPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTL-------TPSSRPIL 224

Query: 199 SAISGKIPSPLSSSYKPMLNNNSF--MWPNSTPVPLLQTTQGLKPVSPPKIQPVSWHHSG 256
           +  S    +P S   +P+L  +S   + P+STP      T  L P + P + P       
Sbjct: 225 TPSSTPTLTPSS---RPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTP------S 275

Query: 257 GTGDCAPQPVDHKVPKSIGTVPADASAH 284
            T    P       P S  T+   +  H
Sbjct: 276 NTPTLTPSSTPTLTPSSTPTLTPSSLWH 303



 Score = 33.9 bits (76), Expect = 0.95
 Identities = 55/235 (23%), Positives = 88/235 (37%), Gaps = 41/235 (17%)

Query: 24  PSGTVPATPPEKPSEGRVWPQAHQQVKPIWK--LEKKQVETLSAGLGPGLLGVPPQPAYF 81
           PS T   TP   P+   + P +   + P  +  L +    TL+    P L          
Sbjct: 4   PSNTPTLTPSSPPT---LTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLT--------- 51

Query: 82  FCPS---TLCSSGTTAVIAGHSSSCYLHSLPDLFNSTLLYRRSSYRQKPYQQLESFCLRS 138
             PS   TL  S T  +    + +    S P L    +L R S+    P          S
Sbjct: 52  --PSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTP----------S 99

Query: 139 SPSEKSPFSLPQKSLPVSLTANKATSSMVFSMAQPMASSSTEPYLCLAAAGENPSGKSLA 198
           SP   +P + P  +   + T   + +  +   + P  + S+ P L        PS + + 
Sbjct: 100 SPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTL-------TPSSRPIL 152

Query: 199 SAISGKIPSPLSSSYKPMLNNNSF--MWPNSTPVPLLQTTQGLKPVSPPKIQPVS 251
           +  S    +P S   +P+L  +S   + P+STP     +T  L P S P + P S
Sbjct: 153 TRSSTPTLTPSS---RPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSS 204


>gi|239745904 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 38.5 bits (88), Expect = 0.039
 Identities = 62/268 (23%), Positives = 100/268 (37%), Gaps = 31/268 (11%)

Query: 24  PSGTVPATPPEKPSEGRVWPQAHQQVKPIWKLEKKQVETLSAGLGPGLLGVPPQPAYFFC 83
           PS T   TP   P+   + P +   + P   L +    TL+    P L    P       
Sbjct: 60  PSNTPTLTPSSTPT---LTPSSTPTLTPQPILTRSSTPTLTPSSPPTLT---PSNTPTLT 113

Query: 84  PS---TLCSSGTTAVIAGHSSSCYLHSLPDLFNST--LLYRRSSYRQKPYQQLESFCLRS 138
           PS   TL  S T  +    + +    S P L  S+  +L R S+    P  +      RS
Sbjct: 114 PSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSR--PILTRS 171

Query: 139 SPSEKSPFSLPQKSLPVSLTANKATSSMVFSMAQPMASSSTEPYLCLAAAGENPSGKSLA 198
           S    +P S P  +   + T   +++  +   ++P+ + S+ P L        PS + + 
Sbjct: 172 STPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTL-------TPSSRPIL 224

Query: 199 SAISGKIPSPLSSSYKPMLNNNSF--MWPNSTPVPLLQTTQGLKPVSPPKIQPVSWHHSG 256
           +  S    +P S   +P+L  +S   + P+STP      T  L P + P + P       
Sbjct: 225 TPSSTPTLTPSS---RPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTP------S 275

Query: 257 GTGDCAPQPVDHKVPKSIGTVPADASAH 284
            T    P       P S  T+   +  H
Sbjct: 276 NTPTLTPSSTPTLTPSSTPTLTPSSLWH 303



 Score = 33.9 bits (76), Expect = 0.95
 Identities = 55/235 (23%), Positives = 88/235 (37%), Gaps = 41/235 (17%)

Query: 24  PSGTVPATPPEKPSEGRVWPQAHQQVKPIWK--LEKKQVETLSAGLGPGLLGVPPQPAYF 81
           PS T   TP   P+   + P +   + P  +  L +    TL+    P L          
Sbjct: 4   PSNTPTLTPSSPPT---LTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLT--------- 51

Query: 82  FCPS---TLCSSGTTAVIAGHSSSCYLHSLPDLFNSTLLYRRSSYRQKPYQQLESFCLRS 138
             PS   TL  S T  +    + +    S P L    +L R S+    P          S
Sbjct: 52  --PSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTP----------S 99

Query: 139 SPSEKSPFSLPQKSLPVSLTANKATSSMVFSMAQPMASSSTEPYLCLAAAGENPSGKSLA 198
           SP   +P + P  +   + T   + +  +   + P  + S+ P L        PS + + 
Sbjct: 100 SPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTL-------TPSSRPIL 152

Query: 199 SAISGKIPSPLSSSYKPMLNNNSF--MWPNSTPVPLLQTTQGLKPVSPPKIQPVS 251
           +  S    +P S   +P+L  +S   + P+STP     +T  L P S P + P S
Sbjct: 153 TRSSTPTLTPSS---RPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSS 204


>gi|156071452 nardilysin isoform b [Homo sapiens]
          Length = 1151

 Score = 37.0 bits (84), Expect = 0.11
 Identities = 20/78 (25%), Positives = 35/78 (44%)

Query: 475 GQSEKERPEEARELDSSDRDISSATDLQPDQAETEDTEEELVDGLEDCCSRDENEEEEGD 534
           G +  +  EE  E +  D D  S  +++ D  E  D E+E  D  +D    ++NE EE +
Sbjct: 138 GNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELE 197

Query: 535 SECSSLSAVSPSESVAMI 552
               +    +  +S A +
Sbjct: 198 ERAEARKKTTEKQSAAAL 215


>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
          Length = 740

 Score = 36.6 bits (83), Expect = 0.15
 Identities = 39/135 (28%), Positives = 59/135 (43%), Gaps = 24/135 (17%)

Query: 476 QSEKERPEEARELDSSDRDISSATDLQPDQAETEDTEEELVDGLEDCCSRDENEE----E 531
           +S++E  EE  E +    D     DL+  Q   ED EEE           DE EE    +
Sbjct: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEE-----------DEEEEAAAGK 490

Query: 532 EGDSECSSLSAVSPSESV---AMISRSCMEILTKPLSNHEKVVRPALIYSLFPNVPPTIY 588
           +GD    S   +S  +++     ISRS  E       N  ++V P+L+ S  P  P +I 
Sbjct: 491 DGDKSPMSSLQISNEKNLEPGKQISRSSGE-----QQNKGRIVSPSLL-SEEPLAPSSID 544

Query: 589 FGTRDERVEKLPWEQ 603
             +  E+ E+L  E+
Sbjct: 545 AESNGEQPEELTLEE 559


>gi|215422388 death-domain associated protein isoform a [Homo
           sapiens]
          Length = 740

 Score = 36.6 bits (83), Expect = 0.15
 Identities = 39/135 (28%), Positives = 59/135 (43%), Gaps = 24/135 (17%)

Query: 476 QSEKERPEEARELDSSDRDISSATDLQPDQAETEDTEEELVDGLEDCCSRDENEE----E 531
           +S++E  EE  E +    D     DL+  Q   ED EEE           DE EE    +
Sbjct: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEE-----------DEEEEAAAGK 490

Query: 532 EGDSECSSLSAVSPSESV---AMISRSCMEILTKPLSNHEKVVRPALIYSLFPNVPPTIY 588
           +GD    S   +S  +++     ISRS  E       N  ++V P+L+ S  P  P +I 
Sbjct: 491 DGDKSPMSSLQISNEKNLEPGKQISRSSGE-----QQNKGRIVSPSLL-SEEPLAPSSID 544

Query: 589 FGTRDERVEKLPWEQ 603
             +  E+ E+L  E+
Sbjct: 545 AESNGEQPEELTLEE 559


>gi|215422366 death-domain associated protein isoform b [Homo
           sapiens]
          Length = 752

 Score = 36.6 bits (83), Expect = 0.15
 Identities = 39/135 (28%), Positives = 59/135 (43%), Gaps = 24/135 (17%)

Query: 476 QSEKERPEEARELDSSDRDISSATDLQPDQAETEDTEEELVDGLEDCCSRDENEE----E 531
           +S++E  EE  E +    D     DL+  Q   ED EEE           DE EE    +
Sbjct: 454 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEE-----------DEEEEAAAGK 502

Query: 532 EGDSECSSLSAVSPSESV---AMISRSCMEILTKPLSNHEKVVRPALIYSLFPNVPPTIY 588
           +GD    S   +S  +++     ISRS  E       N  ++V P+L+ S  P  P +I 
Sbjct: 503 DGDKSPMSSLQISNEKNLEPGKQISRSSGE-----QQNKGRIVSPSLL-SEEPLAPSSID 556

Query: 589 FGTRDERVEKLPWEQ 603
             +  E+ E+L  E+
Sbjct: 557 AESNGEQPEELTLEE 571


>gi|115529449 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 36.6 bits (83), Expect = 0.15
 Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 2/73 (2%)

Query: 476 QSEKERPEEARELDSSDRDISSATDLQPDQAETEDTEEELVDGLEDCCSRDENEEEEGDS 535
           + E E  E+    DSS+    S+     D++E  D  EE  D  ++    D++E+E+ +S
Sbjct: 651 EDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEE--DDEDEDDDEDDDEDEDNES 708

Query: 536 ECSSLSAVSPSES 548
           E SS S+ S  +S
Sbjct: 709 EGSSSSSSSSGDS 721



 Score = 30.8 bits (68), Expect = 8.1
 Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 3/82 (3%)

Query: 476 QSEKERPEEARELDSSDRDISSATDLQPDQAET--EDTEEELVDGLEDCCSRDENEEEEG 533
           +SE E  +E  E D  D D     D   D +E   + +E    D  ED    +E++E+E 
Sbjct: 637 KSESEEDDEEDE-DDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 695

Query: 534 DSECSSLSAVSPSESVAMISRS 555
           D E       + SE  +  S S
Sbjct: 696 DDEDDDEDEDNESEGSSSSSSS 717


>gi|115529451 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 36.6 bits (83), Expect = 0.15
 Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 2/73 (2%)

Query: 476 QSEKERPEEARELDSSDRDISSATDLQPDQAETEDTEEELVDGLEDCCSRDENEEEEGDS 535
           + E E  E+    DSS+    S+     D++E  D  EE  D  ++    D++E+E+ +S
Sbjct: 651 EDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEE--DDEDEDDDEDDDEDEDNES 708

Query: 536 ECSSLSAVSPSES 548
           E SS S+ S  +S
Sbjct: 709 EGSSSSSSSSGDS 721



 Score = 30.8 bits (68), Expect = 8.1
 Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 3/82 (3%)

Query: 476 QSEKERPEEARELDSSDRDISSATDLQPDQAET--EDTEEELVDGLEDCCSRDENEEEEG 533
           +SE E  +E  E D  D D     D   D +E   + +E    D  ED    +E++E+E 
Sbjct: 637 KSESEEDDEEDE-DDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 695

Query: 534 DSECSSLSAVSPSESVAMISRS 555
           D E       + SE  +  S S
Sbjct: 696 DDEDDDEDEDNESEGSSSSSSS 717


>gi|7657671 upstream binding transcription factor, RNA polymerase I
           isoform a [Homo sapiens]
          Length = 764

 Score = 36.6 bits (83), Expect = 0.15
 Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 2/73 (2%)

Query: 476 QSEKERPEEARELDSSDRDISSATDLQPDQAETEDTEEELVDGLEDCCSRDENEEEEGDS 535
           + E E  E+    DSS+    S+     D++E  D  EE  D  ++    D++E+E+ +S
Sbjct: 688 EDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEE--DDEDEDDDEDDDEDEDNES 745

Query: 536 ECSSLSAVSPSES 548
           E SS S+ S  +S
Sbjct: 746 EGSSSSSSSSGDS 758



 Score = 30.8 bits (68), Expect = 8.1
 Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 3/82 (3%)

Query: 476 QSEKERPEEARELDSSDRDISSATDLQPDQAET--EDTEEELVDGLEDCCSRDENEEEEG 533
           +SE E  +E  E D  D D     D   D +E   + +E    D  ED    +E++E+E 
Sbjct: 674 KSESEEDDEEDE-DDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDED 732

Query: 534 DSECSSLSAVSPSESVAMISRS 555
           D E       + SE  +  S S
Sbjct: 733 DDEDDDEDEDNESEGSSSSSSS 754


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 36.6 bits (83), Expect = 0.15
 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 2/89 (2%)

Query: 475  GQSEKERPEEARELDSS--DRDISSATDLQPDQAETEDTEEELVDGLEDCCSRDENEEEE 532
            G   + RP    ELDS   + +  S ++ Q    E E+ EEE  +  +D    D+ +E E
Sbjct: 1016 GVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESE 1075

Query: 533  GDSECSSLSAVSPSESVAMISRSCMEILT 561
             D E ++LS  S  +         + I+T
Sbjct: 1076 NDDEDTALSEASEKDEGDSDEEETVSIVT 1104



 Score = 35.0 bits (79), Expect = 0.43
 Identities = 23/104 (22%), Positives = 45/104 (43%), Gaps = 2/104 (1%)

Query: 457  PQTLGIANVATRLSSIQLG--QSEKERPEEARELDSSDRDISSATDLQPDQAETEDTEEE 514
            P+ +G+     R   +  G  + EKE   E +E    + +     + + D  +  D  +E
Sbjct: 1014 PKGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDE 1073

Query: 515  LVDGLEDCCSRDENEEEEGDSECSSLSAVSPSESVAMISRSCME 558
              +  ED    + +E++EGDS+     ++  S++ A  S    E
Sbjct: 1074 SENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSE 1117



 Score = 30.8 bits (68), Expect = 8.1
 Identities = 24/77 (31%), Positives = 33/77 (42%), Gaps = 6/77 (7%)

Query: 478  EKERPEEARELDSSDRDIS------SATDLQPDQAETEDTEEELVDGLEDCCSRDENEEE 531
            E+E  E+  + DS DRD S      +A     ++ E +  EEE V  +        + E 
Sbjct: 1056 EEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSES 1115

Query: 532  EGDSECSSLSAVSPSES 548
               SE  S S  SPS S
Sbjct: 1116 SESSEFESSSESSPSSS 1132


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.129    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,929,719
Number of Sequences: 37866
Number of extensions: 2543396
Number of successful extensions: 12014
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 164
Number of HSP's that attempted gapping in prelim test: 10971
Number of HSP's gapped (non-prelim): 995
length of query: 1199
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1085
effective length of database: 13,930,794
effective search space: 15114911490
effective search space used: 15114911490
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.