BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|217035131 hypothetical protein LOC55765 isoform 1 [Homo sapiens] (663 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|217035131 hypothetical protein LOC55765 isoform 1 [Homo sapiens] 1360 0.0 gi|217035133 hypothetical protein LOC55765 isoform 2 [Homo sapiens] 1177 0.0 gi|116063562 FERM domain containing 4A [Homo sapiens] 225 9e-59 gi|150010540 FERM domain containing 4B [Homo sapiens] 141 2e-33 gi|15826862 coiled-coil domain containing 120 isoform 3 [Homo sa... 96 1e-19 gi|254039614 coiled-coil domain containing 120 isoform 4 [Homo s... 96 1e-19 gi|254039612 coiled-coil domain containing 120 isoform 2 [Homo s... 96 1e-19 gi|254039610 coiled-coil domain containing 120 isoform 1 [Homo s... 96 1e-19 gi|78042577 MAP7 domain containing 1 [Homo sapiens] 57 5e-08 gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 52 2e-06 gi|225543461 tetratricopeptide repeat, ankyrin repeat and coiled... 49 1e-05 gi|41350201 epsin 1 isoform c [Homo sapiens] 47 4e-05 gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 47 6e-05 gi|37537554 hypothetical protein FLJ37538 [Homo sapiens] 47 6e-05 gi|47132519 Ras association and pleckstrin homology domains 1 is... 47 7e-05 gi|93352554 GPR158-like 1 [Homo sapiens] 46 1e-04 gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s... 46 1e-04 gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ... 46 1e-04 gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ... 46 1e-04 gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo s... 46 1e-04 gi|162951884 R3H domain containing 2 [Homo sapiens] 46 1e-04 gi|222418647 mucin 7, secreted precursor [Homo sapiens] 45 2e-04 gi|222418649 mucin 7, secreted precursor [Homo sapiens] 45 2e-04 gi|222418645 mucin 7, secreted precursor [Homo sapiens] 45 2e-04 gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens] 45 2e-04 gi|122937271 WAS protein homolog associated with actin, golgi me... 45 2e-04 gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 45 2e-04 gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 45 2e-04 gi|56549694 enabled homolog isoform a [Homo sapiens] 45 2e-04 gi|39930375 enabled homolog isoform b [Homo sapiens] 45 2e-04 >gi|217035131 hypothetical protein LOC55765 isoform 1 [Homo sapiens] Length = 663 Score = 1360 bits (3520), Expect = 0.0 Identities = 663/663 (100%), Positives = 663/663 (100%) Query: 1 MLQMPKLNEIPPGRAGRREARGEGRWPGQTGPEAARLEWRAQGQAGGARAPWDSWGSSRL 60 MLQMPKLNEIPPGRAGRREARGEGRWPGQTGPEAARLEWRAQGQAGGARAPWDSWGSSRL Sbjct: 1 MLQMPKLNEIPPGRAGRREARGEGRWPGQTGPEAARLEWRAQGQAGGARAPWDSWGSSRL 60 Query: 61 PTQPGPGWSRCPPSLLCALSFQKSTMESKDEVSDTDSGIILQSGPDSPVSPMKELTHAVH 120 PTQPGPGWSRCPPSLLCALSFQKSTMESKDEVSDTDSGIILQSGPDSPVSPMKELTHAVH Sbjct: 61 PTQPGPGWSRCPPSLLCALSFQKSTMESKDEVSDTDSGIILQSGPDSPVSPMKELTHAVH 120 Query: 121 KQQRALEARLEACLEELRRLCLREAELTGTLPAEYPLKPGEKAPKVRRRIGAAYKLDDWA 180 KQQRALEARLEACLEELRRLCLREAELTGTLPAEYPLKPGEKAPKVRRRIGAAYKLDDWA Sbjct: 121 KQQRALEARLEACLEELRRLCLREAELTGTLPAEYPLKPGEKAPKVRRRIGAAYKLDDWA 180 Query: 181 LHREDPLSSLERQLALQLQITEAARRLCLEENLSRQARRQRKHSMLQEEKKLQELQRCLV 240 LHREDPLSSLERQLALQLQITEAARRLCLEENLSRQARRQRKHSMLQEEKKLQELQRCLV Sbjct: 181 LHREDPLSSLERQLALQLQITEAARRLCLEENLSRQARRQRKHSMLQEEKKLQELQRCLV 240 Query: 241 ERRRNSEPPPAAALPLGRELSASDDSSLSDGLLLEEEESQVPKPPPESPAPPSRPLPPQT 300 ERRRNSEPPPAAALPLGRELSASDDSSLSDGLLLEEEESQVPKPPPESPAPPSRPLPPQT Sbjct: 241 ERRRNSEPPPAAALPLGRELSASDDSSLSDGLLLEEEESQVPKPPPESPAPPSRPLPPQT 300 Query: 301 LEGLQPTGPEAGSPERAPVQNSPWKETSLDHPYEKPRKSSEPWSESSSPATTPQDGPSAS 360 LEGLQPTGPEAGSPERAPVQNSPWKETSLDHPYEKPRKSSEPWSESSSPATTPQDGPSAS Sbjct: 301 LEGLQPTGPEAGSPERAPVQNSPWKETSLDHPYEKPRKSSEPWSESSSPATTPQDGPSAS 360 Query: 361 SLWLLEPASYHVVPIRGVPGQWQGRTSAPATPEIQGRRGQSQSLRVDSFRAGPEGRGRSA 420 SLWLLEPASYHVVPIRGVPGQWQGRTSAPATPEIQGRRGQSQSLRVDSFRAGPEGRGRSA Sbjct: 361 SLWLLEPASYHVVPIRGVPGQWQGRTSAPATPEIQGRRGQSQSLRVDSFRAGPEGRGRSA 420 Query: 421 FPRRRPTHYTVTVPDSCFPATKPPLPHAACHSCSEDSGSDVSSISHPTSPGSSSPDISFL 480 FPRRRPTHYTVTVPDSCFPATKPPLPHAACHSCSEDSGSDVSSISHPTSPGSSSPDISFL Sbjct: 421 FPRRRPTHYTVTVPDSCFPATKPPLPHAACHSCSEDSGSDVSSISHPTSPGSSSPDISFL 480 Query: 481 QPLSPPKTHRHRGAWVPAGSRELVAHHPKLLLPPGYFPAGRYVVVAESPLPPGEWELRRA 540 QPLSPPKTHRHRGAWVPAGSRELVAHHPKLLLPPGYFPAGRYVVVAESPLPPGEWELRRA Sbjct: 481 QPLSPPKTHRHRGAWVPAGSRELVAHHPKLLLPPGYFPAGRYVVVAESPLPPGEWELRRA 540 Query: 541 APGPAYEEEGTPLRYQRLVPSRSRIVRTPSLKDSPAGRGLSKAAVSEELKWWHERARLRS 600 APGPAYEEEGTPLRYQRLVPSRSRIVRTPSLKDSPAGRGLSKAAVSEELKWWHERARLRS Sbjct: 541 APGPAYEEEGTPLRYQRLVPSRSRIVRTPSLKDSPAGRGLSKAAVSEELKWWHERARLRS 600 Query: 601 TRPHSLDRQGAFRVRSLPLGREGFGRALGPRAQVPTVCVLRRSPDGAPVQVFVPEKGEII 660 TRPHSLDRQGAFRVRSLPLGREGFGRALGPRAQVPTVCVLRRSPDGAPVQVFVPEKGEII Sbjct: 601 TRPHSLDRQGAFRVRSLPLGREGFGRALGPRAQVPTVCVLRRSPDGAPVQVFVPEKGEII 660 Query: 661 SQV 663 SQV Sbjct: 661 SQV 663 >gi|217035133 hypothetical protein LOC55765 isoform 2 [Homo sapiens] Length = 578 Score = 1177 bits (3044), Expect = 0.0 Identities = 578/578 (100%), Positives = 578/578 (100%) Query: 86 MESKDEVSDTDSGIILQSGPDSPVSPMKELTHAVHKQQRALEARLEACLEELRRLCLREA 145 MESKDEVSDTDSGIILQSGPDSPVSPMKELTHAVHKQQRALEARLEACLEELRRLCLREA Sbjct: 1 MESKDEVSDTDSGIILQSGPDSPVSPMKELTHAVHKQQRALEARLEACLEELRRLCLREA 60 Query: 146 ELTGTLPAEYPLKPGEKAPKVRRRIGAAYKLDDWALHREDPLSSLERQLALQLQITEAAR 205 ELTGTLPAEYPLKPGEKAPKVRRRIGAAYKLDDWALHREDPLSSLERQLALQLQITEAAR Sbjct: 61 ELTGTLPAEYPLKPGEKAPKVRRRIGAAYKLDDWALHREDPLSSLERQLALQLQITEAAR 120 Query: 206 RLCLEENLSRQARRQRKHSMLQEEKKLQELQRCLVERRRNSEPPPAAALPLGRELSASDD 265 RLCLEENLSRQARRQRKHSMLQEEKKLQELQRCLVERRRNSEPPPAAALPLGRELSASDD Sbjct: 121 RLCLEENLSRQARRQRKHSMLQEEKKLQELQRCLVERRRNSEPPPAAALPLGRELSASDD 180 Query: 266 SSLSDGLLLEEEESQVPKPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWK 325 SSLSDGLLLEEEESQVPKPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWK Sbjct: 181 SSLSDGLLLEEEESQVPKPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWK 240 Query: 326 ETSLDHPYEKPRKSSEPWSESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVPGQWQGR 385 ETSLDHPYEKPRKSSEPWSESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVPGQWQGR Sbjct: 241 ETSLDHPYEKPRKSSEPWSESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVPGQWQGR 300 Query: 386 TSAPATPEIQGRRGQSQSLRVDSFRAGPEGRGRSAFPRRRPTHYTVTVPDSCFPATKPPL 445 TSAPATPEIQGRRGQSQSLRVDSFRAGPEGRGRSAFPRRRPTHYTVTVPDSCFPATKPPL Sbjct: 301 TSAPATPEIQGRRGQSQSLRVDSFRAGPEGRGRSAFPRRRPTHYTVTVPDSCFPATKPPL 360 Query: 446 PHAACHSCSEDSGSDVSSISHPTSPGSSSPDISFLQPLSPPKTHRHRGAWVPAGSRELVA 505 PHAACHSCSEDSGSDVSSISHPTSPGSSSPDISFLQPLSPPKTHRHRGAWVPAGSRELVA Sbjct: 361 PHAACHSCSEDSGSDVSSISHPTSPGSSSPDISFLQPLSPPKTHRHRGAWVPAGSRELVA 420 Query: 506 HHPKLLLPPGYFPAGRYVVVAESPLPPGEWELRRAAPGPAYEEEGTPLRYQRLVPSRSRI 565 HHPKLLLPPGYFPAGRYVVVAESPLPPGEWELRRAAPGPAYEEEGTPLRYQRLVPSRSRI Sbjct: 421 HHPKLLLPPGYFPAGRYVVVAESPLPPGEWELRRAAPGPAYEEEGTPLRYQRLVPSRSRI 480 Query: 566 VRTPSLKDSPAGRGLSKAAVSEELKWWHERARLRSTRPHSLDRQGAFRVRSLPLGREGFG 625 VRTPSLKDSPAGRGLSKAAVSEELKWWHERARLRSTRPHSLDRQGAFRVRSLPLGREGFG Sbjct: 481 VRTPSLKDSPAGRGLSKAAVSEELKWWHERARLRSTRPHSLDRQGAFRVRSLPLGREGFG 540 Query: 626 RALGPRAQVPTVCVLRRSPDGAPVQVFVPEKGEIISQV 663 RALGPRAQVPTVCVLRRSPDGAPVQVFVPEKGEIISQV Sbjct: 541 RALGPRAQVPTVCVLRRSPDGAPVQVFVPEKGEIISQV 578 >gi|116063562 FERM domain containing 4A [Homo sapiens] Length = 1039 Score = 225 bits (574), Expect = 9e-59 Identities = 147/332 (44%), Positives = 196/332 (59%), Gaps = 22/332 (6%) Query: 84 STMESKDEVSDTDSGIILQSGP---DSPVSPMKELTHAVHKQQRALEARLEACLEELRRL 140 + M SK ++ SG +L SG DS S K++ A+ +Q ALE L LEEL++L Sbjct: 353 ANMGSKGKIISGSSGSLLSSGSQESDSSQSAKKDMLAALKSRQEALEETLRQRLEELKKL 412 Query: 141 CLREAELTGTLPAEYPLKPGEKAPKVRRRIGAAYKLDDWAL---HREDPLSSLERQLALQ 197 CLREAELTG LP EYPL PGE+ P VRRRIG A+KLD+ + E L LER+ A+Q Sbjct: 413 CLREAELTGKLPVEYPLDPGEEPPIVRRRIGTAFKLDEQKILPKGEEAELERLEREFAIQ 472 Query: 198 LQITEAARRLCLEENLSRQARRQRKHSMLQEEKKLQELQRCLVERRRNS--EPPPAAALP 255 QITEAARRL + N+S++ ++QRK S L KKLQE++ + E R S +P A+L Sbjct: 473 SQITEAARRLASDPNVSKKLKKQRKTSYLNALKKLQEIENAINENRIKSGKKPTQRASLI 532 Query: 256 LGRELSASDDSSLSDGLLLEEEESQV-----PKPPPES---PAPPS--RPLPPQTLEGLQ 305 + AS+DSSLSD L+LE+E+SQV P P P PPS RP PPQ+LEGL+ Sbjct: 533 IDDGNIASEDSSLSDALVLEDEDSQVTSTISPLHSPHKGLPPRPPSHNRPPPPQSLEGLR 592 Query: 306 PTGPEAGSPERAPVQNSPWKETSLDHPYEKPRKSSEPWSESSSPATTPQDGPSASSLWLL 365 +++P++ W E+SLD PYEK +K S S SSS P G A + Sbjct: 593 QMHYHRNDYDKSPIKPKMWSESSLDEPYEKVKKRSS-HSHSSSHKRFPSTGSCAEAGG-- 649 Query: 366 EPASYHVVPIRGVPGQWQGRTSAPATPEIQGR 397 S PIRG+P W ++S P+TP+++ R Sbjct: 650 GSNSLQNSPIRGLP-HWNSQSSMPSTPDLRVR 680 Score = 45.4 bits (106), Expect = 2e-04 Identities = 24/50 (48%), Positives = 36/50 (72%), Gaps = 2/50 (4%) Query: 557 RLVPSRSRIVRTPSL-KDSPAGRGLSKAAVSEELKWWHERARLRSTRPHS 605 RL PSRS+I+RTPSL ++ +G +AAVS+EL+ W++R+ S + HS Sbjct: 895 RLTPSRSQILRTPSLGREGAHDKGAGRAAVSDELRQWYQRS-TASHKEHS 943 >gi|150010540 FERM domain containing 4B [Homo sapiens] Length = 1034 Score = 141 bits (356), Expect = 2e-33 Identities = 101/298 (33%), Positives = 157/298 (52%), Gaps = 28/298 (9%) Query: 85 TMESKDEVSDTDSGIILQSGP-DSPVSP--MKELTHAVHKQQRALEARLEACLEELRRLC 141 T+E+K + +G ++ SG DS VS +E + K+++ L+ +L +EEL+++C Sbjct: 393 TLEAKSQFIMASNGSLISSGSQDSEVSEEQKREKILELKKKEKLLQEKLLKKVEELKKIC 452 Query: 142 LREAELTGTLPAEYPLKPGEKAPKVRRRIGAAYKLDDWAL-HREDP-LSSLERQLALQLQ 199 LREAELTG +P EYPL GEK P+VRRR+G A+KLDD L EDP L LE +Q + Sbjct: 453 LREAELTGKMPKEYPLNIGEKPPQVRRRVGTAFKLDDNLLPSEEDPALQELESNFLIQQK 512 Query: 200 ITEAARRLCLEENLSRQARRQRKHSMLQEEKKLQELQRCLVERR-RNSEPPPAAALPLGR 258 + EAA++L E +L + +++RK KKLQE++ + E R R + P A L Sbjct: 513 LVEAAKKLANEPDLCKTVKKKRKQDYTDAMKKLQEIENAINEYRIRCGKKPSQKATVLPE 572 Query: 259 ELSASDDSSLSDGLLLEEEESQVPKPPPESPAPPSRP--LPPQTLEGLQPTGPEAGSPER 316 ++ S+ SSLSD ++ P S + P P LPP++L Sbjct: 573 DIIPSESSSLSDTTTYDDPSDAFTFPGQRSSSVPHSPRILPPKSL--------------- 617 Query: 317 APVQNSPWKETSLDHPYEKPRKSSEPWSESSSPATT----PQDGPSASSLWLLEPASY 370 ++ ++++S++ + R+S E S SSP T PQ G S + +L +Y Sbjct: 618 -GIERIHFRKSSINEQFVDTRQSREMLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAY 674 >gi|15826862 coiled-coil domain containing 120 isoform 3 [Homo sapiens] Length = 630 Score = 95.9 bits (237), Expect = 1e-19 Identities = 84/269 (31%), Positives = 125/269 (46%), Gaps = 41/269 (15%) Query: 122 QQRALEARLEACLEELRRLCLREAELTGTLPAEYPLKPGEKAPKVRRRIGAAYKL----D 177 +QR L+ L L+ELR++CL+EAELTG LP E PL+PGE+ VRRR A Sbjct: 38 RQRTLQEALSLKLQELRKVCLQEAELTGQLPPECPLEPGERPQLVRRRPPTARAYPPPHP 97 Query: 178 DWALH-----REDPLSSLERQLALQLQITEAARRLCLEENLSRQARRQRKHSMLQEEKKL 232 + A H E L +LER++++Q QI AARRL L +LS + RR+R+ ++L Sbjct: 98 NQAHHSLCPAEELALEALEREVSVQQQIAAAARRLALAPDLSTEQRRRRRQVQADALRRL 157 Query: 233 QELQRCLVERRRNSEPPPAAALPLGRELSASDDSSLS---------------DGLLLEEE 277 EL+ L + R P LPL + L S S ++ + ++L E Sbjct: 158 HELEEQLRDVRARLGLP---VLPLPQPLPLSTGSVITTQGVCLGMRLAQLSQEDVVLHSE 214 Query: 278 ESQVP--------KPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSL 329 S + + P + RP PP+ + L+ GSPER +PWK Sbjct: 215 SSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAV--SGGSPER----RTPWKPPPS 268 Query: 330 DHPYEKPRKSSEPWSESSSPATTPQDGPS 358 D + + + S +S + P+ S Sbjct: 269 DLYGDLKSRRNSVASPTSPTRSLPRSASS 297 >gi|254039614 coiled-coil domain containing 120 isoform 4 [Homo sapiens] Length = 618 Score = 95.9 bits (237), Expect = 1e-19 Identities = 84/269 (31%), Positives = 125/269 (46%), Gaps = 41/269 (15%) Query: 122 QQRALEARLEACLEELRRLCLREAELTGTLPAEYPLKPGEKAPKVRRRIGAAYKL----D 177 +QR L+ L L+ELR++CL+EAELTG LP E PL+PGE+ VRRR A Sbjct: 26 RQRTLQEALSLKLQELRKVCLQEAELTGQLPPECPLEPGERPQLVRRRPPTARAYPPPHP 85 Query: 178 DWALH-----REDPLSSLERQLALQLQITEAARRLCLEENLSRQARRQRKHSMLQEEKKL 232 + A H E L +LER++++Q QI AARRL L +LS + RR+R+ ++L Sbjct: 86 NQAHHSLCPAEELALEALEREVSVQQQIAAAARRLALAPDLSTEQRRRRRQVQADALRRL 145 Query: 233 QELQRCLVERRRNSEPPPAAALPLGRELSASDDSSLS---------------DGLLLEEE 277 EL+ L + R P LPL + L S S ++ + ++L E Sbjct: 146 HELEEQLRDVRARLGLP---VLPLPQPLPLSTGSVITTQGVCLGMRLAQLSQEDVVLHSE 202 Query: 278 ESQVP--------KPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSL 329 S + + P + RP PP+ + L+ GSPER +PWK Sbjct: 203 SSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAV--SGGSPER----RTPWKPPPS 256 Query: 330 DHPYEKPRKSSEPWSESSSPATTPQDGPS 358 D + + + S +S + P+ S Sbjct: 257 DLYGDLKSRRNSVASPTSPTRSLPRSASS 285 >gi|254039612 coiled-coil domain containing 120 isoform 2 [Homo sapiens] Length = 649 Score = 95.9 bits (237), Expect = 1e-19 Identities = 84/269 (31%), Positives = 125/269 (46%), Gaps = 41/269 (15%) Query: 122 QQRALEARLEACLEELRRLCLREAELTGTLPAEYPLKPGEKAPKVRRRIGAAYKL----D 177 +QR L+ L L+ELR++CL+EAELTG LP E PL+PGE+ VRRR A Sbjct: 26 RQRTLQEALSLKLQELRKVCLQEAELTGQLPPECPLEPGERPQLVRRRPPTARAYPPPHP 85 Query: 178 DWALH-----REDPLSSLERQLALQLQITEAARRLCLEENLSRQARRQRKHSMLQEEKKL 232 + A H E L +LER++++Q QI AARRL L +LS + RR+R+ ++L Sbjct: 86 NQAHHSLCPAEELALEALEREVSVQQQIAAAARRLALAPDLSTEQRRRRRQVQADALRRL 145 Query: 233 QELQRCLVERRRNSEPPPAAALPLGRELSASDDSSLS---------------DGLLLEEE 277 EL+ L + R P LPL + L S S ++ + ++L E Sbjct: 146 HELEEQLRDVRARLGLP---VLPLPQPLPLSTGSVITTQGVCLGMRLAQLSQEDVVLHSE 202 Query: 278 ESQVP--------KPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSL 329 S + + P + RP PP+ + L+ GSPER +PWK Sbjct: 203 SSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAV--SGGSPER----RTPWKPPPS 256 Query: 330 DHPYEKPRKSSEPWSESSSPATTPQDGPS 358 D + + + S +S + P+ S Sbjct: 257 DLYGDLKSRRNSVASPTSPTRSLPRSASS 285 >gi|254039610 coiled-coil domain containing 120 isoform 1 [Homo sapiens] Length = 661 Score = 95.9 bits (237), Expect = 1e-19 Identities = 84/269 (31%), Positives = 125/269 (46%), Gaps = 41/269 (15%) Query: 122 QQRALEARLEACLEELRRLCLREAELTGTLPAEYPLKPGEKAPKVRRRIGAAYKL----D 177 +QR L+ L L+ELR++CL+EAELTG LP E PL+PGE+ VRRR A Sbjct: 38 RQRTLQEALSLKLQELRKVCLQEAELTGQLPPECPLEPGERPQLVRRRPPTARAYPPPHP 97 Query: 178 DWALH-----REDPLSSLERQLALQLQITEAARRLCLEENLSRQARRQRKHSMLQEEKKL 232 + A H E L +LER++++Q QI AARRL L +LS + RR+R+ ++L Sbjct: 98 NQAHHSLCPAEELALEALEREVSVQQQIAAAARRLALAPDLSTEQRRRRRQVQADALRRL 157 Query: 233 QELQRCLVERRRNSEPPPAAALPLGRELSASDDSSLS---------------DGLLLEEE 277 EL+ L + R P LPL + L S S ++ + ++L E Sbjct: 158 HELEEQLRDVRARLGLP---VLPLPQPLPLSTGSVITTQGVCLGMRLAQLSQEDVVLHSE 214 Query: 278 ESQVP--------KPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSL 329 S + + P + RP PP+ + L+ GSPER +PWK Sbjct: 215 SSSLSESGASHDNEEPHGCFSLAERPSPPKAWDQLRAV--SGGSPER----RTPWKPPPS 268 Query: 330 DHPYEKPRKSSEPWSESSSPATTPQDGPS 358 D + + + S +S + P+ S Sbjct: 269 DLYGDLKSRRNSVASPTSPTRSLPRSASS 297 >gi|78042577 MAP7 domain containing 1 [Homo sapiens] Length = 841 Score = 57.0 bits (136), Expect = 5e-08 Identities = 78/316 (24%), Positives = 118/316 (37%), Gaps = 49/316 (15%) Query: 11 PPGRAGRREARGEGRWPGQTGPEAARLEWRAQGQAGGARAPWDSWGSSRLPTQPGPGWSR 70 P GR R+E E P GPE R + AP +S P+ P P + Sbjct: 504 PKGRVRRKEEAKES--PSAAGPEDKSQSKRRASNEKESAAP-----ASPAPS-PAPSPTP 555 Query: 71 CPPSLLCALSFQKSTMESKDEVSDTDSGIILQS-GPDSPVSPMK---------ELTHAVH 120 PP E + TD+ ++ P PV+P K E T + Sbjct: 556 APPQ-----------KEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLA 604 Query: 121 KQQRALEARLEACLEELRRLCLREAELTGTLPAEYPLKPGEKAPKVRRRIGAAYKLDDWA 180 +++R + E +E R R+ + A E+ + RRR + Sbjct: 605 EKRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRR--------EEQ 656 Query: 181 LHREDPLSSLERQLALQLQITEAARRLCLEENLSRQARRQRKHSMLQEEKKLQELQRC-- 238 RE + E Q LQ Q EA R E RQ + KH QE+++ + +R Sbjct: 657 EAREKAQAEQEEQERLQKQKEEAEARS--REEAERQRLEREKHFQQQEQERQERRKRLEE 714 Query: 239 LVERRRNSEPPPAAALPLGRELSASDDS--------SLSDGLLLEEEESQVPKPPPESPA 290 +++R R SE +E +A+ S + S GL E + + P P + Sbjct: 715 IMKRTRKSEVSETKQKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQKEEPIPQEPQWS 774 Query: 291 PPSRPLPPQTLEGLQP 306 PS+ LP + GLQP Sbjct: 775 LPSKELPASLVNGLQP 790 Score = 41.2 bits (95), Expect = 0.003 Identities = 29/84 (34%), Positives = 37/84 (44%), Gaps = 14/84 (16%) Query: 240 VERRRNSEPPPAAALPLGRELSASDDSSLSDGLLLEEEESQVPKPPPESPAPPSRPLPPQ 299 V R+ ++ P+AA P +D S S E+ES P P SPAP P PPQ Sbjct: 508 VRRKEEAKESPSAAGP--------EDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQ 559 Query: 300 TLEGLQPTGPEAGSPERAPVQNSP 323 + P A +P A V SP Sbjct: 560 KEQ------PPAETPTDAAVLTSP 577 Score = 33.9 bits (76), Expect = 0.49 Identities = 41/166 (24%), Positives = 66/166 (39%), Gaps = 22/166 (13%) Query: 281 VPKPPPESP-----APPSRPLP-----PQTLEGLQPTGPEAGSPERAPVQNSPWKETSLD 330 VP PP++P A S+ LP P G +P P+ SP P Sbjct: 44 VPDTPPDTPPAMKNATSSKQLPLEPESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGP 103 Query: 331 HPYEKPRKSSEPWSESSSPAT----TPQDGPSASSLWLL-----EPASYHVVPIRGVPGQ 381 PR+SS+P S ++ PA+ T Q+ A L E + ++ + V + Sbjct: 104 RDARPPRRSSQP-SPTAVPASDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLE 162 Query: 382 WQGRTSAPATPEIQGRRG--QSQSLRVDSFRAGPEGRGRSAFPRRR 425 + + A ++Q RR + Q L+ + RA E R R + + Sbjct: 163 KEEKAKALREKQLQERRRRLEEQRLKAEQRRAALEERQRQKLEKNK 208 Score = 33.1 bits (74), Expect = 0.84 Identities = 21/72 (29%), Positives = 29/72 (40%), Gaps = 2/72 (2%) Query: 282 PKPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSLDHPYEKPRKSSE 341 P+ P P PP L P T P A S ++ P++ P + P P + Sbjct: 29 PEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLE--PESPSGQVGPRPAPPQEES 86 Query: 342 PWSESSSPATTP 353 P SE+ S TP Sbjct: 87 PSSEAKSRGPTP 98 >gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] Length = 1682 Score = 51.6 bits (122), Expect = 2e-06 Identities = 83/335 (24%), Positives = 110/335 (32%), Gaps = 78/335 (23%) Query: 243 RRNSEPPPAAALPLGRELSASDDSSLSDGLL----LEEEESQVPK-----PPPESPAPPS 293 +R +EPP +P S + LS G E++ +P PPP P PP Sbjct: 198 KRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPP 257 Query: 294 RPLPPQTLEGLQPTGP--------------EAGSPER---APVQNSPWKETSLDH--PYE 334 P PP L GL + P +A PER AP + + SL H PY Sbjct: 258 PPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRH-SLPHPYPYP 316 Query: 335 KPRKSSEPWSESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVPGQWQGRTSAPATPEI 394 P ++ P PA P GP R + G A P Sbjct: 317 APAYTAHPPGHRLVPAAPPGPGP------------------RPPGAESHGCLPATRPPGS 358 Query: 395 QGRRGQSQSLRVDSFRAGPEGRGRSAFPRRRPTHYTVTVPDSCFPATKPPLPHAACHSCS 454 R + Q R+DS + P T VP + ++PP S S Sbjct: 359 DLRESRVQRSRMDSSVS--------------PAATTACVP---YAPSRPPGLPGTTTSSS 401 Query: 455 EDSGSDVSSISHPTSPGSSSPDISFLQPLSPPKTHRHRGAWVPAGSRELV---AHHPKLL 511 S S+ +PG D + P H G + + + A P L Sbjct: 402 SSSSSNTGLRGVEPNPGIPGAD-HYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLS 460 Query: 512 LPPGYFPAGRYVVVAESPLPPGEWELRRAAPGPAY 546 LPPG SP PP L R P PA+ Sbjct: 461 LPPG----------PSSPPPPPCPRLLRPPPPPAW 485 Score = 37.0 bits (84), Expect = 0.058 Identities = 48/172 (27%), Positives = 60/172 (34%), Gaps = 36/172 (20%) Query: 248 PPPAAALPLGRELSASDDSSLSDGLLLEEEESQVPKPPP--------------------E 287 PPP A L +A +D + + L E P PPP + Sbjct: 480 PPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQD 539 Query: 288 SPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSLDHPYEKPRKSSEPWSESS 347 S PP+ P P T +G + SP PV P PY +S +P Sbjct: 540 SHTPPTPPTPT-TSSSNSNSGSHSSSPA-GPVSFPP-------PPYLA--RSIDPLPRPP 588 Query: 348 SPATTPQDGPSASSLWLLEPA---SYHVVPIRGV--PGQWQGRTSAPATPEI 394 SPA PQD P L PA S H P + R S P TPE+ Sbjct: 589 SPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEV 640 Score = 35.0 bits (79), Expect = 0.22 Identities = 55/223 (24%), Positives = 83/223 (37%), Gaps = 37/223 (16%) Query: 104 GPDSPVSPMKELTHAVHKQQRALEARLEACLEELRRLCLREAELTG---TLPAEYPLKPG 160 GP +P P L+ + + + LEE+ R C E G T PA+ P+ Sbjct: 891 GPMTPTQPPPPLSLPPARSESEV-------LEEISRACETLVERVGRSATDPAD-PVDTA 942 Query: 161 EKAPKVRRRIGAAYKLDDWALHREDPLSSLERQLALQLQITEAARRLCLEENLSRQARRQ 220 E A R+ + + A S +R+ + RR C ++++ R+ R Sbjct: 943 EPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRAC-KDSVGRRPREG 1001 Query: 221 RKHSMLQEEKKLQELQRCLVERRRNSEPPPAAALPLGRELSASDDSSLSDGLLLEEEESQ 280 R + + K ++ +R L SE GRE S D S Sbjct: 1002 RAKAKAKVPK--EKSRRVLGNLDLQSEEIQ------GREKSRPDLGGASKA--------- 1044 Query: 281 VPKPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSP 323 PP +PAPPS P P QPT P A P + + +P Sbjct: 1045 ---KPPTAPAPPSAPAP-----SAQPTPPSASVPGKKAREEAP 1079 Score = 33.1 bits (74), Expect = 0.84 Identities = 82/365 (22%), Positives = 104/365 (28%), Gaps = 71/365 (19%) Query: 275 EEEESQVPKPPP-ESPA----PPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSL 329 +E+ +P P P +PA PP L P G P P A S P P + Sbjct: 303 QEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRE 362 Query: 330 DHPYEKPRKSSE---------PWSESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVPG 380 SS P++ S P P S+SS V P G+PG Sbjct: 363 SRVQRSRMDSSVSPAATTACVPYAPSRPPGL-PGTTTSSSSSSSSNTGLRGVEPNPGIPG 421 Query: 381 QWQGRTSAPATPEIQGRRGQSQSLRVDSFRAGPEGRGRSAFPRRRPTHYTVTVPDSCFPA 440 +T A GR G S F P + P + P C Sbjct: 422 ADHYQTPALEVSH-HGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSS----PPPPPCPRL 476 Query: 441 TKPPLPHA-----ACHSCSEDSGSDVSSISHPTSPGSSSPDISFLQPLSPPKTHRHRGAW 495 +PP P A AC + ED I G+ P +P PP HR Sbjct: 477 LRPPPPPAWLKGPACRAAREDG-----EILEELFFGTEGPP----RPAPPPLPHREGFLG 527 Query: 496 VPAG----------------------SRELVAHHPKLLLPPGYFPAGRYVVVAESPLP-- 531 PA S H P FP Y+ + PLP Sbjct: 528 PPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRP 587 Query: 532 -------------PGEWELRRAAPGPAYEEEGTPLRYQRLVPSRSRIVRTPSLKDSPAGR 578 P L A P ++ R R +TP + P Sbjct: 588 PSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPG 647 Query: 579 GLSKA 583 LSKA Sbjct: 648 PLSKA 652 Score = 32.0 bits (71), Expect = 1.9 Identities = 63/305 (20%), Positives = 103/305 (33%), Gaps = 50/305 (16%) Query: 209 LEENLSRQARRQRKHSMLQEEKKLQELQRCLVERRRNSEPPPAAALPLGRELSASDDSSL 268 L+E++ ++ +Q+ + + + L+E L ++ P A ++ + ++ Sbjct: 702 LDESIRKEEEQQQHEAGVAPQPPLKEPFASL----QSPFPTDTAPTTTAPAVAVTTTTTT 757 Query: 269 SDGLLLEEEESQVPKPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETS 328 + +EE + P PP P PP PP + QP P SP S Sbjct: 758 TTTTTATQEEEKKP-PPALPPPPPLAKFPPPSQP--QPPPPPPPSP------------AS 802 Query: 329 LDHPYEKPRKSSEPWSESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVPGQWQGRTSA 388 L + + + A + + GP ++ + PG G T+ Sbjct: 803 LLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQY--------------SPGPPSGATAL 848 Query: 389 PATPEIQGRRGQSQ----SLRVDSFRAGPEGRGRSAFPRRRPTHYTVTVPDSCFPATKPP 444 P T +G Q S S GP R R A P T T P P + PP Sbjct: 849 PPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPP--PLSLPP 906 Query: 445 LP---------HAACHSCSEDSGSDVSSISHPTSPGSSSPDISFLQPLSPPKTHRHRGAW 495 AC + E G + + P ++ P S + L PP + Sbjct: 907 ARSESEVLEEISRACETLVERVGRSATDPADPVD--TAEPADSGTERLLPPAQAKEEAGG 964 Query: 496 VPAGS 500 V A S Sbjct: 965 VAAVS 969 >gi|225543461 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 isoform 1 [Homo sapiens] Length = 1861 Score = 49.3 bits (116), Expect = 1e-05 Identities = 77/323 (23%), Positives = 123/323 (38%), Gaps = 53/323 (16%) Query: 192 RQLALQLQITEAARRLCLEENLSRQARRQRKHSMLQEEKKLQELQRCLVERRRNSEPPPA 251 RQ L + A +LC ++ K + + E++ ++LQR ++++ P PA Sbjct: 1384 RQFVAALADLQEAVKLC-------PTNQEVKRLLARVEEECKQLQRS--QQQKQQGPLPA 1434 Query: 252 AALPLGRELSASDDSS--LSDGLLLEEEESQVPKPPPESPAPPSRPLPPQTL-------- 301 PL + D + LSD EE E + P ES +P R P ++ Sbjct: 1435 ---PLNDSENEEDTPTPGLSDHFHSEETEEEETSPQEESVSPTPRSQPSSSVPSSYIRNL 1491 Query: 302 -EGLQPTGPEAGSPERAPVQNSPWKETSLDHPYEKPRKSSEPWSESSSPATTPQDGPSAS 360 EGLQ G RA + S L P +P +P ++ T+ G S Sbjct: 1492 QEGLQSKGRPVSPQSRAGIGKS------LREPVAQPGLLLQPSKQAQIVKTSQHLGSGQS 1545 Query: 361 SLW---LLEPASYHVVPIRGVPGQWQGRTSAPATPEIQG---------------RRGQSQ 402 ++ + S P +PG+ + T ++G R G SQ Sbjct: 1546 AVRNGSMKVQISSQNPPPSPMPGRIAATPAGSRTQHLEGTGTFTTRAGCGHFGDRLGPSQ 1605 Query: 403 SLRVDSFRAGPEGR--GRSAFPRRRPTHYTVTV----PDSCFPATKPPLPHAACHSCSED 456 ++R+ GP ++ R +H +V V P+ AT + H A + S Sbjct: 1606 NVRLQCGENGPAHPLPSKTKTTERLLSHSSVAVDAAPPNQGGLATCSDVRHPASLTSSGS 1665 Query: 457 SGSDVSSISHPTSPGSSSPDISF 479 SGS SSI +S S + SF Sbjct: 1666 SGSPSSSIKMSSSTSSLTSSSSF 1688 >gi|41350201 epsin 1 isoform c [Homo sapiens] Length = 550 Score = 47.4 bits (111), Expect = 4e-05 Identities = 98/397 (24%), Positives = 130/397 (32%), Gaps = 79/397 (19%) Query: 186 PLSSLERQLALQLQITEAARRLCLEENLSRQARRQRKHSMLQEEKKLQELQRCLVERRRN 245 P SS E +L LQL + + EE + R+ R ++E K Sbjct: 178 PQSSGEEELQLQLALAMSKEEADQEERI-RRGDDLRLQMAIEESK--------------- 221 Query: 246 SEPPPAAALPLGRELSASDDSSLSDGLLLEEEESQVPKP---PPESPAPPSRPLPPQTLE 302 RE ++SSL D L + + P P P PAP + +P Sbjct: 222 ------------RETGGKEESSLMD--LADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPT 267 Query: 303 ----GLQPTGPEA---GSPERAPVQNSPWKETSLDHPYEKP-----------RKSSEPWS 344 G P P A G P P PW+ + P P + +PW Sbjct: 268 SDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWG 327 Query: 345 ESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVPGQWQGRTSAPATPEIQGRRGQSQSL 404 SS P GPSAS W PA W G +PA P G Sbjct: 328 --SSDGGVPVSGPSASDPWTPAPA---------FSDPWGG---SPAKPSTNGTTAGGFDT 373 Query: 405 RVDSFRAGPEGRGRSAFPRRRPTHYTVTVPDSCFPATKPPL--PHAACHSCSEDSGS-DV 461 D F R R+A P + + + PA P S +E GS Sbjct: 374 EPDEF--SDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPP 431 Query: 462 SSISHPTSPGSSSPDISFLQP---LSPPKTHRHRGAWVPAGSRELVAHHPKLLLPPGYFP 518 ++ PT P +P+ SFL P L + R P G++ A +P LP G Sbjct: 432 AATPTPTPPTRKTPE-SFLGPNAALVDLDSLVSRPGPTPPGAK---ASNP--FLPGGGPA 485 Query: 519 AGRYVVVAESPLPPGEWELRRAAPGPAYEEEGTPLRY 555 G V P PP L + P G P Y Sbjct: 486 TGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTY 522 >gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo sapiens] Length = 309 Score = 47.0 bits (110), Expect = 6e-05 Identities = 75/297 (25%), Positives = 98/297 (32%), Gaps = 32/297 (10%) Query: 251 AAALPLGRELSASDDSSLSDGLLLEEEESQVPKPPPESPAPPSRP--LPPQTLEGLQPTG 308 ++A L ++S + S+ G E Q P +P PP +P PPQ Q Sbjct: 14 SSAQSLNEDVSQEESPSVISGKP-EGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPP 72 Query: 309 PEAGSPERAPVQNS-------PWKETSLDHPYEKPRKSSEPWSESSSPATTPQDGPSASS 361 P G PE P Q P P + +S P P P G + S Sbjct: 73 PRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQ 132 Query: 362 LWLLEPASYHVVPIRGVPGQWQGRTSAPATPEIQGRRGQSQSLRVDSFRAGPE-----GR 416 P P +G Q QG P PE +G +QS PE G Sbjct: 133 GPPPRPGKPEGPPPQG-GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGG 191 Query: 417 GRSAFPRRRPTHYTVTVPDSCFPAT-KPPLPHAACHSCSEDSGSDVSSISHPTSPGSSSP 475 +S P RP P + PP P S+ HP P P Sbjct: 192 NQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPP 251 Query: 476 DISFLQPLSPPKTHRHRGAWVPAGSRELVAHHPKLLLPPGYFPAGRYVVVAESPLPP 532 +P PP R +G P G +P+ LPP PAG+ + P PP Sbjct: 252 Q-EGNKPQRPPPPGRPQGPPPPGG-------NPQQPLPP---PAGK----PQGPPPP 293 Score = 31.6 bits (70), Expect = 2.5 Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 6/55 (10%) Query: 275 EEEESQVPKPP--PESPAPPS----RPLPPQTLEGLQPTGPEAGSPERAPVQNSP 323 E + Q P PP P+ P PP +PLPP + P P G P Q P Sbjct: 253 EGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQP 307 >gi|37537554 hypothetical protein FLJ37538 [Homo sapiens] Length = 841 Score = 47.0 bits (110), Expect = 6e-05 Identities = 81/329 (24%), Positives = 110/329 (33%), Gaps = 53/329 (16%) Query: 261 SASDDSSLSDGLLLEEEESQVPKPPPES----PAPPSRPLPPQTLEGLQPTG---PEAGS 313 + +D S + EE + +P+ E P P + PPQ L P P + Sbjct: 248 AGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHALPPHAHRRPASAL 307 Query: 314 PERAPVQNSPWKETSLDHPYEKP-----RKSSEPWSESSSPATTPQDGPSASSLWLLEPA 368 P R +P K T + P P R + ++ S + TP DG S + Sbjct: 308 PSRR--DGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKE 365 Query: 369 SYHVVPIRGVPGQWQGRTSAPATPEIQGRR--GQSQSLRVDSFRAGPEGRGRSAFPRRRP 426 P VP + + P P G S R S P+G G+ R P Sbjct: 366 PAGSTPAPQVPARERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGSGQPRGERELP 425 Query: 427 THYTVTVPDSCFPATKPPLPHAACHSCSEDSG-------SDVSSISHPTSP-----GSSS 474 +++ P + PP P A +D S V +H P G+ Sbjct: 426 NSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAGPPLGAGE 485 Query: 475 P----DISFL--------QPLSPPKTHRHRGAWVPAGSRELVAHHPKLLLPPGYFPAGRY 522 P +IS L +P P KT H GA G+ V HH L P P Sbjct: 486 PKTEKEISVLHGMLCTSSRPPVPGKTSPHGGA---MGAAAGVLHHRGCLASPHSLPD--- 539 Query: 523 VVVAESPLPPGEWELRRAAPG----PAYE 547 PL P W A G PAYE Sbjct: 540 --PTVGPLTP-LWTYPATAAGLKRPPAYE 565 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 46.6 bits (109), Expect = 7e-05 Identities = 75/288 (26%), Positives = 99/288 (34%), Gaps = 43/288 (14%) Query: 279 SQVPKPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPER-APV--QNSPWKETSLDHPYEK 335 +QV P P P P PLPPQ T P S + APV Q +P T P +K Sbjct: 756 TQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKK 815 Query: 336 P---RKSSEPWSESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVPGQWQGRTSAPATP 392 S P S + P P + +P + P+ V Q + P TP Sbjct: 816 QPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTP 875 Query: 393 EIQGRRGQSQSLRVDSFRAGPEG-RGRSAFPRRRPTHYTVTVPD---------------- 435 +SQ L+ P+ A P+ +P+ V PD Sbjct: 876 PAM----ESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPP 931 Query: 436 -SCFPATKPPLPHAACHSCSEDSGSDVSSISHPTSPGSSSPDISFLQPLSPPKTHRHRGA 494 S PA PP P A + + SGS S +SPG P PP R+ Sbjct: 932 PSPVPAPPPPPPPTASPT-PDKSGSPGKKTSKTSSPGGKKP---------PPTPQRNSSI 981 Query: 495 WVPAGSRELVAHHPKLLLPPGYFPAGRYVVVAESPLPPGEWELRRAAP 542 +G A HP+ P ++ AES P E AAP Sbjct: 982 KSSSG-----AEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAP 1024 Score = 39.3 bits (90), Expect = 0.012 Identities = 41/145 (28%), Positives = 60/145 (41%), Gaps = 34/145 (23%) Query: 277 EESQVPKPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPER---------------APVQN 321 E S V PPP SP P P PP T PT ++GSP + P +N Sbjct: 922 ESSLVFPPPPPSPVPAPPPPPPPT---ASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRN 978 Query: 322 SPWKETS-LDHPYEKPRKSS--------EPWSESSSPATTPQDGPSASSLWLLEPASYHV 372 S K +S +HP +P++ S P +ES SP+ P+A +P ++ Sbjct: 979 SSIKSSSGAEHP--EPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPP----KPGKLNL 1032 Query: 373 VPIRGVPGQWQGRTSAPATPEIQGR 397 + +PG Q + P + GR Sbjct: 1033 SGV-NLPGVLQQGCVSAKAPVLSGR 1056 Score = 34.7 bits (78), Expect = 0.29 Identities = 28/88 (31%), Positives = 35/88 (39%), Gaps = 12/88 (13%) Query: 277 EESQVPKPPPESPAPP---SRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSLDHPY 333 + S +P P P+ P PP S PP P P P P SP + S P Sbjct: 905 QPSSIPVPSPDFPPPPPESSLVFPP------PPPSPVPAPPPPPPPTASPTPDKS-GSPG 957 Query: 334 EKPRKSSEPWSESSSPATTPQDGPSASS 361 +K K+S P + P TPQ S S Sbjct: 958 KKTSKTSSPGGK--KPPPTPQRNSSIKS 983 Score = 31.6 bits (70), Expect = 2.5 Identities = 60/265 (22%), Positives = 87/265 (32%), Gaps = 40/265 (15%) Query: 281 VPKPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSLDHPYEKPRKSS 340 VP PPP PP P P + L+P P A S + P K + H Sbjct: 709 VPPPPP----PPPPPTPGSAMAQLKP-APCAPSLPQFSAPPPPLKIHQVQH--------- 754 Query: 341 EPWSESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVPGQWQGRTSAPATPEIQGRRGQ 400 +P T P P + L P P+ +P +T AP Sbjct: 755 ---ITQVAPPTPPPPPPIPAPL----PPQAPPKPLVTIPAPTSTKTVAPVV--------- 798 Query: 401 SQSLRVDSFRAGPEGRGRSAFPRRRPTHYTVTVPDSCFPATKPPLPHAACHSCSEDSGSD 460 +Q+ P + + AFP ++ + P P P LP C++ S Sbjct: 799 TQAAPPTPTPPVPPAKKQPAFP---ASYIPPSPPTPPVPVPPPTLPKQQSF-CAKPPPSP 854 Query: 461 VSSISHPTSPGSSSPDISFLQPLSPPKTHRHRGAWVPAGSRELVAHHPKLLLPPGYFPAG 520 +S + +S F P +PP VPA P + P + P+ Sbjct: 855 LSPVPSVVKQIAS----QFPPPPTPPAMESQPLKPVPANVAP--QSPPAVKAKPKWQPSS 908 Query: 521 RYVVVAESPLPPGEWELRRAAPGPA 545 V + P PP E L P P+ Sbjct: 909 IPVPSPDFPPPPPESSLVFPPPPPS 933 Score = 31.2 bits (69), Expect = 3.2 Identities = 15/32 (46%), Positives = 16/32 (50%), Gaps = 2/32 (6%) Query: 282 PKPPPESPAPPSRPLPPQTLEGLQPTGPEAGS 313 P PPP P PP P PP L + P AGS Sbjct: 630 PPPPPPPPPPPPPPPPPPPLP--SQSAPSAGS 659 Score = 30.8 bits (68), Expect = 4.2 Identities = 38/137 (27%), Positives = 52/137 (37%), Gaps = 24/137 (17%) Query: 278 ESQVPKPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSLDHPYEKPR 337 ESQ KP P + AP S P + QP+ SP+ P P E+SL P P Sbjct: 879 ESQPLKPVPANVAPQSPP-AVKAKPKWQPSSIPVPSPDFPP----PPPESSLVFPPPPP- 932 Query: 338 KSSEPWSESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVPGQWQGRTSAPATPEIQGR 397 S PA P P+AS G PG+ +TS+P + Sbjct: 933 --------SPVPAPPPPPPPTASP----------TPDKSGSPGKKTSKTSSPGGKKPPPT 974 Query: 398 RGQSQSLRVDSFRAGPE 414 ++ S++ S PE Sbjct: 975 PQRNSSIKSSSGAEHPE 991 >gi|93352554 GPR158-like 1 [Homo sapiens] Length = 2367 Score = 46.2 bits (108), Expect = 1e-04 Identities = 79/277 (28%), Positives = 110/277 (39%), Gaps = 58/277 (20%) Query: 114 ELTHAVHKQQRALEARLEA---CLEEL-RRLCLREAELTGTLPAEYPLKPGEKAPKVRRR 169 E T A+HK + + R E L+ L RR ++A T + + E P + R Sbjct: 763 EGTPALHKSRSTYDQRREQDPPLLDSLLRRKLAKKASRTESRESV------EGPPALGFR 816 Query: 170 IGAAYKLD-DWALHREDPLSSLERQLALQLQITEA---ARRLCLEENLSRQARRQRKHSM 225 +A+ L L R P +SL++ L++ +A A + LEE RQA+ + Sbjct: 817 SASAHNLTVGERLPRARP-ASLQKSLSVASSREKALLMASQAYLEETY-RQAKER----- 869 Query: 226 LQEEKKLQELQRCLVER--RRNSEPPPAAAL--PLGRELSASDDSSLSDGLLLEEEESQV 281 +E KK + LV R R E P A L P S+S DSS + G L EE ++ Sbjct: 870 -EERKKAKAAMASLVRRPSARRLERPRGAPLSAPPSPAKSSSVDSSHTSGRLHEEARRRL 928 Query: 282 PKPPPESPA-----------------PPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPW 324 P PP P+ L P L L PT +P APV SP Sbjct: 929 PHPPIRHQVSTPILALSGGLGEPRMLSPTSTLAPALLPALAPT----PAPALAPVPVSPQ 984 Query: 325 KETSLDHPYEKPRKSSEPWSESSSPA---TTPQDGPS 358 L + PW + PA PQ+GPS Sbjct: 985 SPNLLTYIC--------PWENAELPAKQENVPQEGPS 1013 >gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo sapiens] Length = 816 Score = 45.8 bits (107), Expect = 1e-04 Identities = 49/171 (28%), Positives = 72/171 (42%), Gaps = 18/171 (10%) Query: 216 QARRQRKHSMLQEEKKLQELQRCLVERRRNSEPPPAAALPLGRELSASDDSSLSDGLLLE 275 + RR+R+ + EK+ QE +R ER + P+ G LS +D S L + Sbjct: 519 EKRRRRQERAKEREKRRQERER--KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMA 576 Query: 276 EEES----QVPKPPPE-SPAP-PSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSL 329 + VP P P +P P P +P P QPTGP+ P+ A + P + + Sbjct: 577 RPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQ---PQSAGSTSGPVPQPAC 633 Query: 330 DHPYEKPRKSSEPWSESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVPG 380 P P + P P P A+S LL A+ +VP G+PG Sbjct: 634 PPPGPAPHPTGPP-----GPIPVPAPPQIATSTSLL--AAQSLVPPPGLPG 677 >gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo sapiens] Length = 816 Score = 45.8 bits (107), Expect = 1e-04 Identities = 49/171 (28%), Positives = 72/171 (42%), Gaps = 18/171 (10%) Query: 216 QARRQRKHSMLQEEKKLQELQRCLVERRRNSEPPPAAALPLGRELSASDDSSLSDGLLLE 275 + RR+R+ + EK+ QE +R ER + P+ G LS +D S L + Sbjct: 519 EKRRRRQERAKEREKRRQERER--KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMA 576 Query: 276 EEES----QVPKPPPE-SPAP-PSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSL 329 + VP P P +P P P +P P QPTGP+ P+ A + P + + Sbjct: 577 RPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQ---PQSAGSTSGPVPQPAC 633 Query: 330 DHPYEKPRKSSEPWSESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVPG 380 P P + P P P A+S LL A+ +VP G+PG Sbjct: 634 PPPGPAPHPTGPP-----GPIPVPAPPQIATSTSLL--AAQSLVPPPGLPG 677 >gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo sapiens] Length = 816 Score = 45.8 bits (107), Expect = 1e-04 Identities = 49/171 (28%), Positives = 72/171 (42%), Gaps = 18/171 (10%) Query: 216 QARRQRKHSMLQEEKKLQELQRCLVERRRNSEPPPAAALPLGRELSASDDSSLSDGLLLE 275 + RR+R+ + EK+ QE +R ER + P+ G LS +D S L + Sbjct: 519 EKRRRRQERAKEREKRRQERER--KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMA 576 Query: 276 EEES----QVPKPPPE-SPAP-PSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSL 329 + VP P P +P P P +P P QPTGP+ P+ A + P + + Sbjct: 577 RPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQ---PQSAGSTSGPVPQPAC 633 Query: 330 DHPYEKPRKSSEPWSESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVPG 380 P P + P P P A+S LL A+ +VP G+PG Sbjct: 634 PPPGPAPHPTGPP-----GPIPVPAPPQIATSTSLL--AAQSLVPPPGLPG 677 >gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo sapiens] Length = 677 Score = 45.8 bits (107), Expect = 1e-04 Identities = 49/171 (28%), Positives = 72/171 (42%), Gaps = 18/171 (10%) Query: 216 QARRQRKHSMLQEEKKLQELQRCLVERRRNSEPPPAAALPLGRELSASDDSSLSDGLLLE 275 + RR+R+ + EK+ QE +R ER + P+ G LS +D S L + Sbjct: 380 EKRRRRQERAKEREKRRQERER--KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMA 437 Query: 276 EEES----QVPKPPPE-SPAP-PSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSL 329 + VP P P +P P P +P P QPTGP+ P+ A + P + + Sbjct: 438 RPAAPALTSVPAPAPAPTPTPTPVQPTSPPPGPVAQPTGPQ---PQSAGSTSGPVPQPAC 494 Query: 330 DHPYEKPRKSSEPWSESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVPG 380 P P + P P P A+S LL A+ +VP G+PG Sbjct: 495 PPPGPAPHPTGPP-----GPIPVPAPPQIATSTSLL--AAQSLVPPPGLPG 538 >gi|162951884 R3H domain containing 2 [Homo sapiens] Length = 976 Score = 45.8 bits (107), Expect = 1e-04 Identities = 50/173 (28%), Positives = 68/173 (39%), Gaps = 32/173 (18%) Query: 250 PAAALPLGREL---SASDDSSLSDGLLLEEEESQVPKPPPESPAPPSRPLPPQTLEGLQP 306 PAA +P+ + + + +S S G L Q P +SP+P S P PQ G+ P Sbjct: 643 PAAGVPVYYSMIPPAQQNGTSPSVGFLQPPGSEQYQMP--QSPSPCSPPQMPQQYSGVSP 700 Query: 307 TG----------PEAGSPERAP--VQNSPWKETSLDHPYEKPRKSSEPWSE-------SS 347 +G P P + P VQ S K S+D +KP P S SS Sbjct: 701 SGPGVVVMQLNVPNGPQPPQNPSMVQWSHCKYYSMDQRGQKPGDLYSPDSSPQANTQMSS 760 Query: 348 SPATTPQDGPSASSLWLLEPASYHVVPI--------RGVPGQWQGRTSAPATP 392 SP T+P P+ S + L + P+ G P Q GR S P Sbjct: 761 SPVTSPTQSPAPSPVTSLSSVCTGLSPLPVLTQFPRPGGPAQGDGRYSLLGQP 813 >gi|222418647 mucin 7, secreted precursor [Homo sapiens] Length = 377 Score = 45.4 bits (106), Expect = 2e-04 Identities = 51/205 (24%), Positives = 74/205 (36%), Gaps = 23/205 (11%) Query: 282 PKPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSLDHPYEKPRKSSE 341 P P +PAPPS PP+T P P A + +AP +S ET+ P P + Sbjct: 170 PTPSATTPAPPSSSAPPETTAA--PPTPSATT--QAPPSSSAPPETTAAPP-TPPATTPA 224 Query: 342 PWSESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVPGQWQGRTSAPATPEIQGRRGQS 401 P S S+ P TT P S P S P T+ P TP S Sbjct: 225 PPSSSAPPETTA--APPTPSATTPAPLSSSAPP---------ETTAVPPTPSATTLDPSS 273 Query: 402 QSLRVDSFRAGPEGRGRSAFPRRRPTHYTVTVPDSCFPATKPPLPHAACHSCSEDSGSDV 461 S ++ A P + P P T P + P + + D+ Sbjct: 274 ASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPT-------TLAPDTSETS 326 Query: 462 SSISHPTSPGSSSPDISFLQPLSPP 486 ++ +H T+ ++ + QP S P Sbjct: 327 AAPTHQTTTSVTTQTTTTKQPTSAP 351 Score = 43.5 bits (101), Expect = 6e-04 Identities = 38/125 (30%), Positives = 54/125 (43%), Gaps = 9/125 (7%) Query: 245 NSEPPPAAALPLGRELSASDDSSLSDGLLLEEEESQVPKPPPESPAPPSRPLPPQTLEGL 304 +S PP A P + S S E + P PP +PAPPS PP+T Sbjct: 182 SSAPPETTAAPPTPSATTQAPPSSSAP---PETTAAPPTPPATTPAPPSSSAPPETTAA- 237 Query: 305 QPTGPEAGSPERAPVQNSPWKETSLDHPYEKPRKSSEPWSESSSPATTPQDGPSASSLWL 364 P P A +P AP+ +S ET+ P P ++ S +S+P T P+ S+ Sbjct: 238 -PPTPSATTP--APLSSSAPPETTAVPP--TPSATTLDPSSASAPPETTAAPPTPSATTP 292 Query: 365 LEPAS 369 P+S Sbjct: 293 APPSS 297 Score = 37.4 bits (85), Expect = 0.045 Identities = 33/122 (27%), Positives = 50/122 (40%), Gaps = 12/122 (9%) Query: 245 NSEPPPAAALPLGRELSASDDSSLSDGLLLEEEESQVPKPPPESPAPPSRPLPPQTLEGL 304 +S PP A+P + D SS S E + P P +PAPPS P P +T Sbjct: 251 SSAPPETTAVPPTPSATTLDPSSASAP---PETTAAPPTPSATTPAPPSSPAPQET---- 303 Query: 305 QPTGPEAGSPERAPVQNSP-WKETSLDHPYEKPRKSSEPWSESSSPATTPQDGPSASSLW 363 T +P +P +P ETS ++ + + + P + P G + S + Sbjct: 304 --TAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAP--GQNKISRF 359 Query: 364 LL 365 LL Sbjct: 360 LL 361 Score = 32.3 bits (72), Expect = 1.4 Identities = 45/211 (21%), Positives = 78/211 (36%), Gaps = 29/211 (13%) Query: 282 PKPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSLDHPYEKPRKSSE 341 PK PP PP P P Q P P+ S P + + S+ P + ++ Sbjct: 72 PKLPPSPNNPPKFPNPHQ-----PPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTL 126 Query: 342 P----WSESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVPGQWQGRTSAPATPEIQGR 397 P ++++ ++ ++ ++SS+ L P + Q T+AP TP Sbjct: 127 PNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAP---------QDTTAAPPTPSATTP 177 Query: 398 RGQSQSLRVDSFRAGPEGRGRSAFPRRRPTHYTVTVPDSCFPATKPPLPHAACHSCSEDS 457 S S ++ A P + P T PAT P P S Sbjct: 178 APPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPP---------SS 228 Query: 458 GSDVSSISHPTSPGSSSPDISFLQPLSPPKT 488 + + + P +P +++P + L +PP+T Sbjct: 229 SAPPETTAAPPTPSATTP--APLSSSAPPET 257 >gi|222418649 mucin 7, secreted precursor [Homo sapiens] Length = 377 Score = 45.4 bits (106), Expect = 2e-04 Identities = 51/205 (24%), Positives = 74/205 (36%), Gaps = 23/205 (11%) Query: 282 PKPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSLDHPYEKPRKSSE 341 P P +PAPPS PP+T P P A + +AP +S ET+ P P + Sbjct: 170 PTPSATTPAPPSSSAPPETTAA--PPTPSATT--QAPPSSSAPPETTAAPP-TPPATTPA 224 Query: 342 PWSESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVPGQWQGRTSAPATPEIQGRRGQS 401 P S S+ P TT P S P S P T+ P TP S Sbjct: 225 PPSSSAPPETTA--APPTPSATTPAPLSSSAPP---------ETTAVPPTPSATTLDPSS 273 Query: 402 QSLRVDSFRAGPEGRGRSAFPRRRPTHYTVTVPDSCFPATKPPLPHAACHSCSEDSGSDV 461 S ++ A P + P P T P + P + + D+ Sbjct: 274 ASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPT-------TLAPDTSETS 326 Query: 462 SSISHPTSPGSSSPDISFLQPLSPP 486 ++ +H T+ ++ + QP S P Sbjct: 327 AAPTHQTTTSVTTQTTTTKQPTSAP 351 Score = 43.5 bits (101), Expect = 6e-04 Identities = 38/125 (30%), Positives = 54/125 (43%), Gaps = 9/125 (7%) Query: 245 NSEPPPAAALPLGRELSASDDSSLSDGLLLEEEESQVPKPPPESPAPPSRPLPPQTLEGL 304 +S PP A P + S S E + P PP +PAPPS PP+T Sbjct: 182 SSAPPETTAAPPTPSATTQAPPSSSAP---PETTAAPPTPPATTPAPPSSSAPPETTAA- 237 Query: 305 QPTGPEAGSPERAPVQNSPWKETSLDHPYEKPRKSSEPWSESSSPATTPQDGPSASSLWL 364 P P A +P AP+ +S ET+ P P ++ S +S+P T P+ S+ Sbjct: 238 -PPTPSATTP--APLSSSAPPETTAVPP--TPSATTLDPSSASAPPETTAAPPTPSATTP 292 Query: 365 LEPAS 369 P+S Sbjct: 293 APPSS 297 Score = 37.4 bits (85), Expect = 0.045 Identities = 33/122 (27%), Positives = 50/122 (40%), Gaps = 12/122 (9%) Query: 245 NSEPPPAAALPLGRELSASDDSSLSDGLLLEEEESQVPKPPPESPAPPSRPLPPQTLEGL 304 +S PP A+P + D SS S E + P P +PAPPS P P +T Sbjct: 251 SSAPPETTAVPPTPSATTLDPSSASAP---PETTAAPPTPSATTPAPPSSPAPQET---- 303 Query: 305 QPTGPEAGSPERAPVQNSP-WKETSLDHPYEKPRKSSEPWSESSSPATTPQDGPSASSLW 363 T +P +P +P ETS ++ + + + P + P G + S + Sbjct: 304 --TAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAP--GQNKISRF 359 Query: 364 LL 365 LL Sbjct: 360 LL 361 Score = 32.3 bits (72), Expect = 1.4 Identities = 45/211 (21%), Positives = 78/211 (36%), Gaps = 29/211 (13%) Query: 282 PKPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSLDHPYEKPRKSSE 341 PK PP PP P P Q P P+ S P + + S+ P + ++ Sbjct: 72 PKLPPSPNNPPKFPNPHQ-----PPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTL 126 Query: 342 P----WSESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVPGQWQGRTSAPATPEIQGR 397 P ++++ ++ ++ ++SS+ L P + Q T+AP TP Sbjct: 127 PNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAP---------QDTTAAPPTPSATTP 177 Query: 398 RGQSQSLRVDSFRAGPEGRGRSAFPRRRPTHYTVTVPDSCFPATKPPLPHAACHSCSEDS 457 S S ++ A P + P T PAT P P S Sbjct: 178 APPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPP---------SS 228 Query: 458 GSDVSSISHPTSPGSSSPDISFLQPLSPPKT 488 + + + P +P +++P + L +PP+T Sbjct: 229 SAPPETTAAPPTPSATTP--APLSSSAPPET 257 >gi|222418645 mucin 7, secreted precursor [Homo sapiens] Length = 377 Score = 45.4 bits (106), Expect = 2e-04 Identities = 51/205 (24%), Positives = 74/205 (36%), Gaps = 23/205 (11%) Query: 282 PKPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSLDHPYEKPRKSSE 341 P P +PAPPS PP+T P P A + +AP +S ET+ P P + Sbjct: 170 PTPSATTPAPPSSSAPPETTAA--PPTPSATT--QAPPSSSAPPETTAAPP-TPPATTPA 224 Query: 342 PWSESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVPGQWQGRTSAPATPEIQGRRGQS 401 P S S+ P TT P S P S P T+ P TP S Sbjct: 225 PPSSSAPPETTA--APPTPSATTPAPLSSSAPP---------ETTAVPPTPSATTLDPSS 273 Query: 402 QSLRVDSFRAGPEGRGRSAFPRRRPTHYTVTVPDSCFPATKPPLPHAACHSCSEDSGSDV 461 S ++ A P + P P T P + P + + D+ Sbjct: 274 ASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPT-------TLAPDTSETS 326 Query: 462 SSISHPTSPGSSSPDISFLQPLSPP 486 ++ +H T+ ++ + QP S P Sbjct: 327 AAPTHQTTTSVTTQTTTTKQPTSAP 351 Score = 43.5 bits (101), Expect = 6e-04 Identities = 38/125 (30%), Positives = 54/125 (43%), Gaps = 9/125 (7%) Query: 245 NSEPPPAAALPLGRELSASDDSSLSDGLLLEEEESQVPKPPPESPAPPSRPLPPQTLEGL 304 +S PP A P + S S E + P PP +PAPPS PP+T Sbjct: 182 SSAPPETTAAPPTPSATTQAPPSSSAP---PETTAAPPTPPATTPAPPSSSAPPETTAA- 237 Query: 305 QPTGPEAGSPERAPVQNSPWKETSLDHPYEKPRKSSEPWSESSSPATTPQDGPSASSLWL 364 P P A +P AP+ +S ET+ P P ++ S +S+P T P+ S+ Sbjct: 238 -PPTPSATTP--APLSSSAPPETTAVPP--TPSATTLDPSSASAPPETTAAPPTPSATTP 292 Query: 365 LEPAS 369 P+S Sbjct: 293 APPSS 297 Score = 37.4 bits (85), Expect = 0.045 Identities = 33/122 (27%), Positives = 50/122 (40%), Gaps = 12/122 (9%) Query: 245 NSEPPPAAALPLGRELSASDDSSLSDGLLLEEEESQVPKPPPESPAPPSRPLPPQTLEGL 304 +S PP A+P + D SS S E + P P +PAPPS P P +T Sbjct: 251 SSAPPETTAVPPTPSATTLDPSSASAP---PETTAAPPTPSATTPAPPSSPAPQET---- 303 Query: 305 QPTGPEAGSPERAPVQNSP-WKETSLDHPYEKPRKSSEPWSESSSPATTPQDGPSASSLW 363 T +P +P +P ETS ++ + + + P + P G + S + Sbjct: 304 --TAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAP--GQNKISRF 359 Query: 364 LL 365 LL Sbjct: 360 LL 361 Score = 32.3 bits (72), Expect = 1.4 Identities = 45/211 (21%), Positives = 78/211 (36%), Gaps = 29/211 (13%) Query: 282 PKPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPVQNSPWKETSLDHPYEKPRKSSE 341 PK PP PP P P Q P P+ S P + + S+ P + ++ Sbjct: 72 PKLPPSPNNPPKFPNPHQ-----PPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTL 126 Query: 342 P----WSESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVPGQWQGRTSAPATPEIQGR 397 P ++++ ++ ++ ++SS+ L P + Q T+AP TP Sbjct: 127 PNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAP---------QDTTAAPPTPSATTP 177 Query: 398 RGQSQSLRVDSFRAGPEGRGRSAFPRRRPTHYTVTVPDSCFPATKPPLPHAACHSCSEDS 457 S S ++ A P + P T PAT P P S Sbjct: 178 APPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPP---------SS 228 Query: 458 GSDVSSISHPTSPGSSSPDISFLQPLSPPKT 488 + + + P +P +++P + L +PP+T Sbjct: 229 SAPPETTAAPPTPSATTP--APLSSSAPPET 257 >gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens] Length = 2390 Score = 45.4 bits (106), Expect = 2e-04 Identities = 52/190 (27%), Positives = 76/190 (40%), Gaps = 38/190 (20%) Query: 188 SSLERQLALQLQITEAARRLCLEENLSRQARRQRKHSMLQEEKKLQELQRCLVERRRNSE 247 S ++R A Q R C E L+ R+++ +EE++ R++ Sbjct: 2050 SLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEE---------RRKQPPA 2100 Query: 248 PPPAAALPLGRELSASDDSSLSDGLLLEEEESQVPKPPPESPAP----------PSRP-L 296 P P A++P G + S + + P+PPP + AP PS+P L Sbjct: 2101 PEPTASVPPGDLVGGQTASDTT-------WDGTQPRPPPSTQAPSVNGVCTDGEPSQPLL 2153 Query: 297 PPQTLEGLQ-PTGPEAGSPERAPVQNSPWKE----TSLDHPYEKPRKSSEPWSESSSPAT 351 Q LE P GP GS + A N P E T P P+ S +ES+ AT Sbjct: 2154 GQQRLEHSSFPEGPGPGSGDEA---NGPRGERQTRTRGPAPSAMPQSRS---TESAHAAT 2207 Query: 352 TPQDGPSASS 361 P GP S+ Sbjct: 2208 LPPRGPEPSA 2217 >gi|122937271 WAS protein homolog associated with actin, golgi membranes and microtubules [Homo sapiens] Length = 809 Score = 45.4 bits (106), Expect = 2e-04 Identities = 27/72 (37%), Positives = 34/72 (47%), Gaps = 3/72 (4%) Query: 276 EEESQVPKPPPESPAPPSRPLPPQTLEGLQPTGPEAGSPE---RAPVQNSPWKETSLDHP 332 EE S P PPP P PP P PP L L + A RAPV++ + + P Sbjct: 634 EELSLPPPPPPPPPPPPPPPPPPPPLRALSSSSQAATHQNLGFRAPVKDDQPRPLVCESP 693 Query: 333 YEKPRKSSEPWS 344 E+PR S E +S Sbjct: 694 AERPRDSLESFS 705 >gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] Length = 1120 Score = 45.4 bits (106), Expect = 2e-04 Identities = 56/197 (28%), Positives = 74/197 (37%), Gaps = 51/197 (25%) Query: 236 QRCLVERRRNSEPP--PAAALPL--------GRELSASDDSSLSDGLLLEEEESQVPK-- 283 +R L E SEPP PA A P G E + S +GL EE + K Sbjct: 822 RRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQR 881 Query: 284 PPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPV--QNSPWKETSLDHPYEKPRKSSE 341 P P P P P+PP GL E+ + +R P + P + L S+ Sbjct: 882 PKPAGPPPRETPVPP----GLDFNLTESDTVKRRPKCREREPLQTALLAFGVA----SAT 933 Query: 342 PWSESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVP---------------------- 379 P + P+ TP + P ASSL EP+S +P +GVP Sbjct: 934 PGPAAPLPSPTPGESPPASSLPQPEPSS---LPAQGVPTPLAPSPAMQPPVPPCPGPGLE 990 Query: 380 ----GQWQGRTSAPATP 392 +W G T PA P Sbjct: 991 SSAASRWNGETEPPAAP 1007 Score = 43.1 bits (100), Expect = 8e-04 Identities = 96/382 (25%), Positives = 128/382 (33%), Gaps = 56/382 (14%) Query: 187 LSSLERQLALQLQITEAARRLCLE---------ENLSRQARRQRKHSMLQEEKKLQELQR 237 L+ L R L ++E RRL EN A + Q + ELQ Sbjct: 537 LAELRRGLLQGEALSEGGRRLAKGPELMAIEGLENGEGPATAGPRLLTFQGSELSPELQA 596 Query: 238 CLVERRRNSEPPPAAALPLGRELSA-SDDSSLSDGLLLEEEESQVPKPPPESPAPPSRPL 296 + P P A P + A S S S + P PP E P Sbjct: 597 AMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTER 656 Query: 297 PPQTLEGLQPTGP----------EAGSPERAPVQNSPWKETSLDHPYEKPRKSSEPWSES 346 PP+ L GP SP P +PW + L P P P S Sbjct: 657 PPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRS 716 Query: 347 ---SSPATTPQD------GPSASSLWLLEPASYHVVPIRGVPGQWQ-GRTSAPATPEIQG 396 S P T D GP S+L SY + R PG+ RTS TP Sbjct: 717 HSLSRPGPTEGDAEGEAEGPVGSTL-----GSYATLTRR--PGRSALVRTSPSVTPTPAR 769 Query: 397 RRGQSQSLRVDSFRAGPEGRGRSAFPRRRPTHYTVTVPDSCFPATKPPLPHAAC-----H 451 +SQS + + R GP P +R + + P+ P + P P Sbjct: 770 GTPRSQSFALRARRKGPPPP-----PPKRLSSVSGPSPEPP-PLDESPGPKEGATGPRRR 823 Query: 452 SCSEDSGSDVSSISHPTSPGSSSPDISFLQPLSPPKTHRHRGAWVPAGSRELVAHHPKLL 511 + SE +G S P +P + D +P P T RG+ +G A L Sbjct: 824 TLSEPAGP--SEPPGPPAPAGPASDTEEEEP-GPEGTPPSRGS---SGEGLPFAEEGNLT 877 Query: 512 LPPGYFPAGRYVVVAESPLPPG 533 + PAG E+P+PPG Sbjct: 878 IKQRPKPAG--PPPRETPVPPG 897 >gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] Length = 1202 Score = 45.4 bits (106), Expect = 2e-04 Identities = 56/197 (28%), Positives = 74/197 (37%), Gaps = 51/197 (25%) Query: 236 QRCLVERRRNSEPP--PAAALPL--------GRELSASDDSSLSDGLLLEEEESQVPK-- 283 +R L E SEPP PA A P G E + S +GL EE + K Sbjct: 904 RRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQR 963 Query: 284 PPPESPAPPSRPLPPQTLEGLQPTGPEAGSPERAPV--QNSPWKETSLDHPYEKPRKSSE 341 P P P P P+PP GL E+ + +R P + P + L S+ Sbjct: 964 PKPAGPPPRETPVPP----GLDFNLTESDTVKRRPKCREREPLQTALLAFGVA----SAT 1015 Query: 342 PWSESSSPATTPQDGPSASSLWLLEPASYHVVPIRGVP---------------------- 379 P + P+ TP + P ASSL EP+S +P +GVP Sbjct: 1016 PGPAAPLPSPTPGESPPASSLPQPEPSS---LPAQGVPTPLAPSPAMQPPVPPCPGPGLE 1072 Query: 380 ----GQWQGRTSAPATP 392 +W G T PA P Sbjct: 1073 SSAASRWNGETEPPAAP 1089 Score = 43.1 bits (100), Expect = 8e-04 Identities = 96/382 (25%), Positives = 128/382 (33%), Gaps = 56/382 (14%) Query: 187 LSSLERQLALQLQITEAARRLCLE---------ENLSRQARRQRKHSMLQEEKKLQELQR 237 L+ L R L ++E RRL EN A + Q + ELQ Sbjct: 619 LAELRRGLLQGEALSEGGRRLAKGPELMAIEGLENGEGPATAGPRLLTFQGSELSPELQA 678 Query: 238 CLVERRRNSEPPPAAALPLGRELSA-SDDSSLSDGLLLEEEESQVPKPPPESPAPPSRPL 296 + P P A P + A S S S + P PP E P Sbjct: 679 AMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTER 738 Query: 297 PPQTLEGLQPTGP----------EAGSPERAPVQNSPWKETSLDHPYEKPRKSSEPWSES 346 PP+ L GP SP P +PW + L P P P S Sbjct: 739 PPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRS 798 Query: 347 ---SSPATTPQD------GPSASSLWLLEPASYHVVPIRGVPGQWQ-GRTSAPATPEIQG 396 S P T D GP S+L SY + R PG+ RTS TP Sbjct: 799 HSLSRPGPTEGDAEGEAEGPVGSTL-----GSYATLTRR--PGRSALVRTSPSVTPTPAR 851 Query: 397 RRGQSQSLRVDSFRAGPEGRGRSAFPRRRPTHYTVTVPDSCFPATKPPLPHAAC-----H 451 +SQS + + R GP P +R + + P+ P + P P Sbjct: 852 GTPRSQSFALRARRKGPPPP-----PPKRLSSVSGPSPEPP-PLDESPGPKEGATGPRRR 905 Query: 452 SCSEDSGSDVSSISHPTSPGSSSPDISFLQPLSPPKTHRHRGAWVPAGSRELVAHHPKLL 511 + SE +G S P +P + D +P P T RG+ +G A L Sbjct: 906 TLSEPAGP--SEPPGPPAPAGPASDTEEEEP-GPEGTPPSRGS---SGEGLPFAEEGNLT 959 Query: 512 LPPGYFPAGRYVVVAESPLPPG 533 + PAG E+P+PPG Sbjct: 960 IKQRPKPAG--PPPRETPVPPG 979 >gi|56549694 enabled homolog isoform a [Homo sapiens] Length = 591 Score = 45.1 bits (105), Expect = 2e-04 Identities = 44/161 (27%), Positives = 58/161 (36%), Gaps = 35/161 (21%) Query: 191 ERQLALQLQITEAARRLCLEENLSRQARRQRKHSMLQEEKKLQELQRCLVERRRNSE--- 247 ERQ + + E RL +E L RQ R R+ QE ++L+ L+R ER R + Sbjct: 194 ERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLER 253 Query: 248 ---------------PPPAAALPLGRELSASDDSSLSDGLLLEEEESQVPK--------- 283 P + PL L D S+ GL + ++ P Sbjct: 254 EQLEWERERRISSAAAPASVETPLNSVLG--DSSASEPGLQAASQPAETPSQQGIVLGPL 311 Query: 284 -PPPESPAPP-----SRPLPPQTLEGLQPTGPEAGSPERAP 318 PPP P PP S LPP P P G P P Sbjct: 312 APPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPP 352 >gi|39930375 enabled homolog isoform b [Homo sapiens] Length = 570 Score = 45.1 bits (105), Expect = 2e-04 Identities = 44/161 (27%), Positives = 58/161 (36%), Gaps = 35/161 (21%) Query: 191 ERQLALQLQITEAARRLCLEENLSRQARRQRKHSMLQEEKKLQELQRCLVERRRNSE--- 247 ERQ + + E RL +E L RQ R R+ QE ++L+ L+R ER R + Sbjct: 194 ERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLER 253 Query: 248 ---------------PPPAAALPLGRELSASDDSSLSDGLLLEEEESQVPK--------- 283 P + PL L D S+ GL + ++ P Sbjct: 254 EQLEWERERRISSAAAPASVETPLNSVLG--DSSASEPGLQAASQPAETPSQQGIVLGPL 311 Query: 284 -PPPESPAPP-----SRPLPPQTLEGLQPTGPEAGSPERAP 318 PPP P PP S LPP P P G P P Sbjct: 312 APPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPP 352 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.131 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 35,116,602 Number of Sequences: 37866 Number of extensions: 2217618 Number of successful extensions: 18862 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 197 Number of HSP's successfully gapped in prelim test: 1147 Number of HSP's that attempted gapping in prelim test: 12429 Number of HSP's gapped (non-prelim): 5612 length of query: 663 length of database: 18,247,518 effective HSP length: 109 effective length of query: 554 effective length of database: 14,120,124 effective search space: 7822548696 effective search space used: 7822548696 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.