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Search of human proteins with 215599324
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|215599324 coiled-coil domain containing 114 isoform 2 [Homo
sapiens]
(670 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|215599324 coiled-coil domain containing 114 isoform 2 [Homo s... 1301 0.0
gi|22749217 coiled-coil domain containing 63 [Homo sapiens] 171 2e-42
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 80 6e-15
gi|55770834 centromere protein F [Homo sapiens] 69 1e-11
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 69 1e-11
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 68 2e-11
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 67 5e-11
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 67 5e-11
gi|38044112 restin isoform b [Homo sapiens] 67 7e-11
gi|4506751 restin isoform a [Homo sapiens] 67 7e-11
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 65 2e-10
gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens] 64 6e-10
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 62 1e-09
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 62 2e-09
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 62 2e-09
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 62 2e-09
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 60 7e-09
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 60 9e-09
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 59 1e-08
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 59 1e-08
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 59 1e-08
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 59 1e-08
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 59 1e-08
gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] 59 1e-08
gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] 59 1e-08
gi|118498362 kinectin 1 isoform b [Homo sapiens] 59 2e-08
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 59 2e-08
gi|31982906 cingulin-like 1 [Homo sapiens] 58 2e-08
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 57 4e-08
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 57 4e-08
>gi|215599324 coiled-coil domain containing 114 isoform 2 [Homo
sapiens]
Length = 670
Score = 1301 bits (3366), Expect = 0.0
Identities = 670/670 (100%), Positives = 670/670 (100%)
Query: 1 MEGERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLL 60
MEGERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLL
Sbjct: 1 MEGERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLL 60
Query: 61 KGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILEN 120
KGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILEN
Sbjct: 61 KGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILEN 120
Query: 121 QLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTS 180
QLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTS
Sbjct: 121 QLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTS 180
Query: 181 AYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPDV 240
AYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPDV
Sbjct: 181 AYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPDV 240
Query: 241 LEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEERNFAE 300
LEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEERNFAE
Sbjct: 241 LEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEERNFAE 300
Query: 301 FNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERL 360
FNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERL
Sbjct: 301 FNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERL 360
Query: 361 EARFQDVRGQLEKLKADIQLLFTKAHCDSSMIDDLLGVKTSMGDRDMGLFLSLIEKRLVE 420
EARFQDVRGQLEKLKADIQLLFTKAHCDSSMIDDLLGVKTSMGDRDMGLFLSLIEKRLVE
Sbjct: 361 EARFQDVRGQLEKLKADIQLLFTKAHCDSSMIDDLLGVKTSMGDRDMGLFLSLIEKRLVE 420
Query: 421 LLTVQAFLHAQSFTSLADAALLVLGQSLEDLPKKMAPLQPPDTLEDPPGFEASDDYPMSR 480
LLTVQAFLHAQSFTSLADAALLVLGQSLEDLPKKMAPLQPPDTLEDPPGFEASDDYPMSR
Sbjct: 421 LLTVQAFLHAQSFTSLADAALLVLGQSLEDLPKKMAPLQPPDTLEDPPGFEASDDYPMSR 480
Query: 481 EELLSQVEKLVELQEQAEAQRQKDLAAAAAKLDGTLSVDLASTQRAGSSTVLVPTRHPHA 540
EELLSQVEKLVELQEQAEAQRQKDLAAAAAKLDGTLSVDLASTQRAGSSTVLVPTRHPHA
Sbjct: 481 EELLSQVEKLVELQEQAEAQRQKDLAAAAAKLDGTLSVDLASTQRAGSSTVLVPTRHPHA 540
Query: 541 IPGSILSHKTSRDRGSLGHVTFGGLSSSTGHLPSHITHGDPNTGHVTFGSTSASSGGHVT 600
IPGSILSHKTSRDRGSLGHVTFGGLSSSTGHLPSHITHGDPNTGHVTFGSTSASSGGHVT
Sbjct: 541 IPGSILSHKTSRDRGSLGHVTFGGLSSSTGHLPSHITHGDPNTGHVTFGSTSASSGGHVT 600
Query: 601 FRPVSASSYLGSTGYVGSSRGGENTEGGVESGGTASDSSGGLGSSRDHVSSTGPASSTGP 660
FRPVSASSYLGSTGYVGSSRGGENTEGGVESGGTASDSSGGLGSSRDHVSSTGPASSTGP
Sbjct: 601 FRPVSASSYLGSTGYVGSSRGGENTEGGVESGGTASDSSGGLGSSRDHVSSTGPASSTGP 660
Query: 661 GSSTSKDSRG 670
GSSTSKDSRG
Sbjct: 661 GSSTSKDSRG 670
>gi|22749217 coiled-coil domain containing 63 [Homo sapiens]
Length = 563
Score = 171 bits (434), Expect = 2e-42
Identities = 116/431 (26%), Positives = 229/431 (53%), Gaps = 12/431 (2%)
Query: 1 MEGERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLL 60
M R+++ Q+I Q +EI+ L+ + ++ + +S ++ R + + LL
Sbjct: 41 MVESRKSFKFRNQQKIASQYKEIKTLKTEQDEITLLLSLMKSSRNMNRSEKNYMELRLLL 100
Query: 61 KGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILEN 120
+ + +A I+ L+ LD++I + E +I + K + + + K++++I ILE
Sbjct: 101 QTKEDYEALIKSLKVLLAELDEKILQMEKKI-ANQKQIFAKMQEANNPRKLQKQIHILET 159
Query: 121 QLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTS 180
+L+ VT HFD L NA LR+E++ LR ++ Y NV ++L+ + ++ I S+
Sbjct: 160 RLNLVTVHFDKMLTTNAKLRKEIEDLRFEKAAYDNVYQQLQHCLLMEKKTMNLAIEQSSQ 219
Query: 181 AYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPDV 240
AY R EA A+M +++R +K+ +Q +E + L+R H +L FL +K NDR +
Sbjct: 220 AYEQRVEAMARMAAMKDRQKKDTSQYNLEIRELERLYAHESKLKSFLLVKLNDRN---EF 276
Query: 241 LEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEERNFAE 300
E+ +++ A+ K ++ YE A +L +L + + L++ +L EE+NFA
Sbjct: 277 EEQAKREEALKAKKHVKKNRGESFESYEVAHLRLLKLAESGNLNQLIEDFLAKEEKNFAR 336
Query: 301 FNFINEQNLELEHVQEEIKEMQEALVSARA----SKDDQHLLQEQQQKVLQQRMDKVHSE 356
F ++ E N ++E + + + +Q+ ++ R+ S DD H + Q L+ ++ K E
Sbjct: 337 FTYVTELNNDMEMMHKRTQRIQDEIILLRSQQKLSHDDNHSVLRQ----LEDKLRKTTEE 392
Query: 357 AERLEARFQDVRGQLEKLKADIQLLFTKAHCDSSMIDDLLGVKTSMGDRDMGLFLSLIEK 416
A+ E+++ +V L+ LK ++ LF K +CD++ I LG + D ++ + ++IEK
Sbjct: 393 ADMYESKYGEVSKTLDLLKNSVEKLFKKINCDATKILVQLGETGKVTDINLPQYFAIIEK 452
Query: 417 RLVELLTVQAF 427
+ +LL ++ +
Sbjct: 453 KTNDLLLLETY 463
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 80.1 bits (196), Expect = 6e-15
Identities = 72/393 (18%), Positives = 185/393 (47%), Gaps = 27/393 (6%)
Query: 10 KEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKR----LRDSQRLENMDRLLKG--- 62
+E+ ++ K E+++ +E + ++Q+ + + +++R L Q D L K
Sbjct: 278 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 337
Query: 63 -RAQVQAEIEE----------LQEQTRALDKQIQEWETRIFTHSKNVRSPGF-ILDQKVK 110
A++QA++EE +E+ +++IQEWE +I + +R I +Q+ K
Sbjct: 338 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 397
Query: 111 IRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHL 170
+RR+ ++ + +++ + + +R + +++ + ++ K+ ++
Sbjct: 398 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE 457
Query: 171 VSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLK 230
R+E +AKM E+ ++E + + + + RQ E++H K++
Sbjct: 458 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQE---EKIHEQEKIR 514
Query: 231 NNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQ-- 288
+++ + + + ++E++ E E +W+ Q+ + E+ + K + M + + Q
Sbjct: 515 EEEKRQEQEEMWRQEEKIREQEE-IWR--QKEKIHEQEEKIRKQEEKMWRQEEKMHDQEE 571
Query: 289 KYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQ 348
K E EE+ + + I EQ ++ +E+I+E +E +Q +Q++ +Q+
Sbjct: 572 KIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE 631
Query: 349 RMDKVHSEAERLEARFQDVRGQLEKLKADIQLL 381
+ +K+ + E++ + + +R Q EK++ +++
Sbjct: 632 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 664
Score = 57.8 bits (138), Expect = 3e-08
Identities = 69/369 (18%), Positives = 162/369 (43%), Gaps = 35/369 (9%)
Query: 4 ERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQV----KRLRDSQRL----EN 55
E+ +E ++I +Q E++RR EE+ + + ++ + + +++R + + E
Sbjct: 379 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 438
Query: 56 MDRLLKGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRI 115
R L+ + Q +I E QE+ R +++I+E E R +K R I +Q+ KIR +
Sbjct: 439 KIRELEEKMHEQEKIRE-QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 497
Query: 116 RILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDR--KLKKEIHHLHHLVST 173
+ Q +++ + + +R R+E + + + + + K++IH +
Sbjct: 498 EKMWRQEEKI---HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKI-- 552
Query: 174 LILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNND 233
+ + KM E+ +E + + + + RQ + + ++ +
Sbjct: 553 ------------RKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEK 600
Query: 234 RQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLEI 293
+ ++ +++E++ GE E + QE + E+ + + + + E + +K E
Sbjct: 601 IREQEEMTQEQEEKMGEQEEKM--CEQEEKMQEQEEKMRRQEEKIREQE-----KKIREQ 653
Query: 294 EERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKV 353
EE+ + + EQ ++ +E++ E +E + Q +Q+ L+Q+ +K+
Sbjct: 654 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 713
Query: 354 HSEAERLEA 362
E LEA
Sbjct: 714 QEHQEHLEA 722
Score = 54.3 bits (129), Expect = 4e-07
Identities = 83/402 (20%), Positives = 173/402 (43%), Gaps = 65/402 (16%)
Query: 2 EGERRA---YSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQR--LENM 56
E E++A + + + + + Q+ IR L + +LQ+ + +Q+ VK+L R + +
Sbjct: 169 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 228
Query: 57 DRLLKGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIR 116
K +++ + + Q + D+ I+E + +
Sbjct: 229 HDSWKFAGELEQALSAVATQKKKADRYIEE------------------------LTKERD 264
Query: 117 ILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNR-YLNVDRKLKKEIH---------- 165
L +L R T + +NA L+E+L L+ +++ LNV ++LK+++
Sbjct: 265 ALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNV-KELKRKLERAKLLLPQQQ 323
Query: 166 ---HLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEK----EEAQSEMEAQVLQRQIL 218
HL L S A EE + L +++ EK EE E E ++ +++
Sbjct: 324 LQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 383
Query: 219 HLEQLHHFLKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTS-----QERLVLCYEDALNK 273
EQ + + R+ + + EK EK + E +W+ QE ++ E+ + +
Sbjct: 384 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ-EEMMWEKEEKMRRQEEMMWEKEEKIRE 442
Query: 274 LSQLMGESDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKD 333
L + M E + + Q+ EE E EQ ++ +E+I+E +E + ++
Sbjct: 443 LEEKMHEQE-KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI------RE 495
Query: 334 DQHLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEKLK 375
+ + Q++K+ +Q +K+ E +R E +++ Q EK++
Sbjct: 496 QEEKMWRQEEKIHEQ--EKIREEEKRQEQ--EEMWRQEEKIR 533
Score = 31.6 bits (70), Expect = 2.5
Identities = 20/92 (21%), Positives = 50/92 (54%), Gaps = 6/92 (6%)
Query: 3 GERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRL--ENMDRLL 60
GE+ E +++ +Q E++RR EE ++ Q + Q +++R+ + + E +++
Sbjct: 616 GEQEEKMCEQEEKMQEQEEKMRRQEE---KIREQEKKIREQEEKIREQEEMMQEQEEKMW 672
Query: 61 KGRAQVQAEIEELQEQTRALDKQIQE-WETRI 91
+ ++ + E++QEQ + +Q ++ WE +
Sbjct: 673 EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 704
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 69.3 bits (168), Expect = 1e-11
Identities = 105/549 (19%), Positives = 213/549 (38%), Gaps = 66/549 (12%)
Query: 11 EVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRD----------SQRLENMDRLL 60
E + +NK +E+ R + +A + ++K+L + S R ++
Sbjct: 331 EKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIK 390
Query: 61 KGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKV-KIRRRIRILE 119
+ + Q E+ Q + LD++ + + R+ + ++ +L ++ K+ + LE
Sbjct: 391 EKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLE 450
Query: 120 NQLD-------RVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVS 172
N L+ R F ++ LR ++ ++ + N + + +E+ HL +
Sbjct: 451 NNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELK 510
Query: 173 TLILSSTSAYAVREEAKAKMG----LLRERAEKE-------------------EAQSEME 209
+ + EE KAK +LR+ EK E Q +
Sbjct: 511 NIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCS 570
Query: 210 AQVLQRQILHLEQLHHFLKLKNNDRQPDPDVLEKREKQAGEVAE-----GVWKTSQERLV 264
+L+++ H+EQL+ L + + LE ++K+ E+ E WK+ E+L+
Sbjct: 571 QDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLL 630
Query: 265 LCYEDALNKLSQLMGESDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEA 324
E L + + L Q +I+ + E + ++ E++ EI+ +
Sbjct: 631 TQMESEKENLQSKINHLETCLKTQ---QIKSHEYNER--VRTLEMDRENLSVEIRNLHNV 685
Query: 325 LVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEKLKADIQLL--- 381
L S + Q L + Q+ + K E E + + + GQ+E L+ +QLL
Sbjct: 686 LDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNE 745
Query: 382 -FTKAHCDSSMIDDLLGVKTSMGDRDMGLFLSLIEKRLVELLTVQAFLHAQSFTSLADAA 440
K C + + ++ + +D L + +R + Q +H + +
Sbjct: 746 IMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQG 805
Query: 441 LLVLGQS-----LEDLPKKMAPLQ-PPDTLEDPPGFEASDDYPMSREELLSQVEKLVELQ 494
+ +S + PK A LQ D+LE F M+ +L Q E+LV+++
Sbjct: 806 SMPSERSECRLEADQSPKNSAILQNRVDSLE----FSLESQKQMN-SDLQKQCEELVQIK 860
Query: 495 EQAEAQRQK 503
+ E K
Sbjct: 861 GEIEENLMK 869
Score = 50.8 bits (120), Expect = 4e-06
Identities = 94/480 (19%), Positives = 191/480 (39%), Gaps = 105/480 (21%)
Query: 1 MEGERRAYSKEVHQR------INKQLEEIRRLEEVRGDLQVQISAA--------QNQVKR 46
+ E+ +K++ ++ ++K L + L E + ++QI QNQ+K
Sbjct: 2208 LRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKE 2267
Query: 47 LRDSQRL------------ENMDRLLKGRAQVQAEIEELQEQTRALDKQIQEWETRIFTH 94
L ++ +++D ++ Q++ IE+L+ + A +K+ + +
Sbjct: 2268 LNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKK----QLCVLQQ 2323
Query: 95 SKNVRSPGFILDQKVK-IRRRIRILENQLDRVTCHFDNQLVRNAALRE------------ 141
K +L +V+ + R + I + +N L+
Sbjct: 2324 LKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGL 2383
Query: 142 ELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEK 201
ELD++ I R+ N+ +L+KE + L I++S+ ++E+ + K+ + K
Sbjct: 2384 ELDVVTI-RSEKENLTNELQKEQERISELE---IINSSFENILQEKEQEKVQM------K 2433
Query: 202 EEAQSEMEAQVLQRQILHLEQ----LHHFLKLKNNDRQPDPDVLEKREKQAGEVAEG--- 254
E++ + ME +LQ Q+ L + LH+ + Q +E E + ++ +G
Sbjct: 2434 EKSSTAME--MLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDE 2491
Query: 255 ------VWKTSQERLVLCYEDALNKLSQLMGE--------SDPDLLVQKYLEIEERNFAE 300
V ++S L+ ED KL + E D + LV K ++E E
Sbjct: 2492 AKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVE----GE 2547
Query: 301 FNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQ-----RMDK--- 352
EQNLEL ++ E+++ + L S AS D + + K L+ +MDK
Sbjct: 2548 HQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSF 2607
Query: 353 -----------------VHSEAERLEARFQDVRGQLEKLKADIQLLFTKAHCDSSMIDDL 395
+H A++ +++ G+ +L ++QLL + + +L
Sbjct: 2608 VEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKEL 2667
Score = 49.3 bits (116), Expect = 1e-05
Identities = 86/395 (21%), Positives = 174/395 (44%), Gaps = 52/395 (13%)
Query: 10 KEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDS--QRLENMDRLLKGRAQVQ 67
+EVHQ + + +E++R E Q+ I+ + +R DS ++EN++R L+ + Q
Sbjct: 2112 EEVHQ-LRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQ 2170
Query: 68 -----------AEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIR 116
AE+E L+ Q + + ++ +E + T + +K + ++I+
Sbjct: 2171 ELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVT----------LRSEKENLTKQIQ 2220
Query: 117 ILENQLDRVTCHFDNQLVRNAALREELDLLRID-RNRYLNVDRKLKKEIHHLHHLVSTL- 174
+ QL + D L +L EE + I + L+ ++ L+ V+ L
Sbjct: 2221 EKQGQLSEL----DKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALC 2276
Query: 175 ----ILSSTSAYA---VREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFL 227
I+ +T + EE + + + + RA + EA + + VLQ Q+ E L
Sbjct: 2277 GDQEIMKATEQSLDPPIEEEHQLRNSIEKLRA-RLEADEKKQLCVLQ-QLKESEHHADLL 2334
Query: 228 KLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGE-----SD 282
K + + + + ++ ++ A AE K E L E L L + S+
Sbjct: 2335 KGRVENLERELEIARTNQEHAALEAENS-KGEVETLKAKIEGMTQSLRGLELDVVTIRSE 2393
Query: 283 PDLLVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQ 342
+ L + L+ E+ +E IN E++ +E KE ++ + ++S + L + Q
Sbjct: 2394 KENLTNE-LQKEQERISELEIINSS---FENILQE-KEQEKVQMKEKSSTAMEML--QTQ 2446
Query: 343 QKVLQQRMDKVHSEAERLEARFQDVRGQLEKLKAD 377
K L +R+ +H++ E +A+ Q++ Q+E L+ +
Sbjct: 2447 LKELNERVAALHNDQEACKAKEQNLSSQVECLELE 2481
Score = 45.4 bits (106), Expect = 2e-04
Identities = 86/453 (18%), Positives = 186/453 (41%), Gaps = 59/453 (13%)
Query: 10 KEVHQRINKQLEEI--RRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQVQ 67
+++ ++IN+Q + +L+ DL+ Q +Q+ +K+ R+ + D+L K + +
Sbjct: 538 RDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKK-REHHIEQLNDKLSKTEKESK 596
Query: 68 AEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLDRVTC 127
A + L+ + + ++ +E S+N + + +K ++ +I LE TC
Sbjct: 597 ALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLE------TC 650
Query: 128 HFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSAYAVREE 187
Q +++ E + L +DR L EI +LH+++ + + + E
Sbjct: 651 -LKTQQIKSHEYNERVRTLEMDREN-------LSVEIRNLHNVLDSKSVEVETQKLAYME 702
Query: 188 AKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNND--------RQPDPD 239
+ K ++ +KE ++ L Q+ E L H L+L +N+ + +
Sbjct: 703 LQQKAEFSDQKHQKEIENMCLKTSQLTGQV---EDLEHKLQLLSNEIMDKDRCYQDLHAE 759
Query: 240 VLEKREKQAGEVAEGVWKTSQERLVLCYEDAL---NKLSQLMGE--SDPDLLVQKYLEIE 294
R+ + A V +R +L ++ + + ++GE S P + LE +
Sbjct: 760 YESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSERSECRLEAD 819
Query: 295 E--RNFAEF-NFINEQNLELEHVQEEIKEMQ---EALVSARASKDDQHLLQEQQQKVL-- 346
+ +N A N ++ LE ++ ++Q E LV + ++ + EQ +
Sbjct: 820 QSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVA 879
Query: 347 --QQRMDKVHSEAERLEARFQDVRGQLEKLKADIQLLFTKAHCDSSMIDD---------- 394
QR+ K+ + + + LE + ++QLL K + + I +
Sbjct: 880 ETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLED 939
Query: 395 ------LLGVKTSMGDRDMGLFLSLIEKRLVEL 421
LL S+ ++M +SL ++ + EL
Sbjct: 940 SLKELQLLSETLSLEKKEMSSIISLNKREIEEL 972
Score = 40.0 bits (92), Expect = 0.007
Identities = 101/549 (18%), Positives = 217/549 (39%), Gaps = 105/549 (19%)
Query: 15 RINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQVQAE--IEE 72
R+ + E RL V D ++ + N++K L L+ + + K A ++ E + E
Sbjct: 1775 RVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGE 1834
Query: 73 LQEQTRALDKQI-------QEWETRIFTHS---------KNVRSPGFILDQKVKI----R 112
L+++ L +++ QE R+ T + S I D K+ +
Sbjct: 1835 LKKENSDLSEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWK 1894
Query: 113 RRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVS 172
R +EN+L R+ + + + AL E DL + + L+K+ + ++
Sbjct: 1895 ERFLDVENELSRIRS--EKASIEHEALYLEADLEVVQTEKLC-----LEKDNENKQKVIV 1947
Query: 173 TLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNN 232
L + + R + + ++ + ++ + SE + Q H + H +++
Sbjct: 1948 CLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEA 2007
Query: 233 DRQPDPDVLEKREKQAGEVAEGVWKTS-QERLVLCYEDAL----------NKLSQLMGES 281
+ + ++L+ E+ + KT QE+L +D+ N+++QL E
Sbjct: 2008 EVKEKTELLQTLSSDVSELLKD--KTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEK 2065
Query: 282 DPDLLVQKYLEIEER-NFAEFNFIN-------------EQNLELEHVQEEIKEMQEALVS 327
+ LLV++ ++ R + +++ +N E L L QEE+ +++ +
Sbjct: 2066 E--LLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEK 2123
Query: 328 ARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEKLKADIQLLFTKAHC 387
R + E++Q + +++ + E + L+ + +++ +L+ + + +L+ A
Sbjct: 2124 LRVRIE----ADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAEN 2179
Query: 388 DSSMIDDLLGVKTSMGDRDMGLFLSLIEKRLVELLTVQAFLHAQSFTSLADAALLVLGQS 447
+ ++ L KT + +M L + E LV L + + L Q
Sbjct: 2180 SKAEVETL---KTQI--EEMARSLKVFELDLVTLRSEKENLTKQ---------------- 2218
Query: 448 LEDLPKKMAPLQPPDTLEDPPGFEASDDYPMSREELLSQVEKLVELQEQAEAQRQKDLAA 507
+ +K L D +LLS + L+E +EQAE Q +++
Sbjct: 2219 ---IQEKQGQLSELD-------------------KLLSSFKSLLEEKEQAEIQIKEESKT 2256
Query: 508 AAAKLDGTL 516
A L L
Sbjct: 2257 AVEMLQNQL 2265
Score = 37.0 bits (84), Expect = 0.059
Identities = 73/359 (20%), Positives = 152/359 (42%), Gaps = 62/359 (17%)
Query: 41 QNQVKRLR---DSQRLENMD--RLLKGRAQVQAEIEE-LQEQTRALDKQIQEWETRIFTH 94
QN+V L +SQ+ N D + + Q++ EIEE L + + + E RI
Sbjct: 829 QNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKL 888
Query: 95 SKNVRSPGFILDQKVKIRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYL 154
++ + Q V + + LEN+ + QL+ + E+ ++ + ++ +L
Sbjct: 889 QEDTSA-----HQNV-VAETLSALENKEKEL------QLLNDKVETEQAEIQELKKSNHL 936
Query: 155 NVDRKLKKEIHHLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQ 214
L+ + L L TL L ++ K + + E ++ E+ A + Q
Sbjct: 937 -----LEDSLKELQLLSETLSLEKKEMSSIISLNKRE---IEELTQENGTLKEINASLNQ 988
Query: 215 RQILHLEQLHHFLKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKL 274
++ +++ F + +++REK E+++ + QE+L+L
Sbjct: 989 EKMNLIQKSESFA-----------NYIDEREKSISELSD---QYKQEKLILLQR------ 1028
Query: 275 SQLMGESDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVS------- 327
+ G + DL QKY +E+N +NE E+ + E+++++EA
Sbjct: 1029 CEETGNAYEDLS-QKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLT 1087
Query: 328 --ARASKDDQHLLQEQQ--QKVLQQRM----DKVHSEAERLEARFQDVRGQLEKLKADI 378
A A + +Q+L+ E + Q+ L+ M + SEA L+ ++ + K++ ++
Sbjct: 1088 KLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEV 1146
Score = 33.9 bits (76), Expect = 0.50
Identities = 107/571 (18%), Positives = 219/571 (38%), Gaps = 99/571 (17%)
Query: 10 KEVHQRINKQLEEIRRLEEVRGDLQVQISA-------------AQNQVKRLRDSQRLENM 56
+++ ++ NK++EE +RLE LQ + ++ A++Q S + E
Sbjct: 165 EDLKEKYNKEVEERKRLEAEVKALQAKKASQTLPQATMNHRDIARHQASSSVFSWQQEKT 224
Query: 57 DRLLKGRAQ---VQAEI--------EELQEQTRALDKQIQEWETRIFTHSKNVRSPGFIL 105
L +Q ++ + +E+ L ++ + F +S + +
Sbjct: 225 PSHLSSNSQRTPIRRDFSASYFSGEQEVTPSRSTLQIGKRDANSSFFDNSSSPHLLDQLK 284
Query: 106 DQKVKIRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIH 165
Q ++R +I LE +L Q+ + L+ +L+ +++ V K + E
Sbjct: 285 AQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDE-- 342
Query: 166 HLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHH 225
++ +T+ Y ++A K L ++ +K + Q + LEQ
Sbjct: 343 ---------LVRTTAQY---DQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQ--- 387
Query: 226 FLKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDL 285
K+K +++ ++ R++++ + + + RL + A N + L E D
Sbjct: 388 --KIKEKEKEFQEEL--SRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLT 443
Query: 286 LVQKYLEIEERNFAE--------FNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHL 337
V++ LE F + F + EL EE+K+ L S K +
Sbjct: 444 SVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVC 503
Query: 338 LQEQQQKVLQQRMDKVHSEAERLEAR-------FQDVRGQ---------LEKLKADIQLL 381
E + K ++Q +++ + AE ++A+ +D++ + LEKLK + L
Sbjct: 504 HLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADL 563
Query: 382 FTKAHCDSSMID------DLLGVKTSMGDRDMGLFLSLIE--KRLVELLTVQAFLHAQSF 433
+ C ++ + L K S +++ LS +E K+ E L + L + +
Sbjct: 564 EKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFS-CW 622
Query: 434 TSLADAALLVLGQSLEDLPKKMAPLQPPDTLEDPPGFEASD---DYPMSREELLSQVEKL 490
S + L + E+L K+ L+ + E ++ M RE L ++ L
Sbjct: 623 KSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNL 682
Query: 491 ------------------VELQEQAEAQRQK 503
+ELQ++AE QK
Sbjct: 683 HNVLDSKSVEVETQKLAYMELQQKAEFSDQK 713
Score = 32.3 bits (72), Expect = 1.5
Identities = 78/394 (19%), Positives = 152/394 (38%), Gaps = 42/394 (10%)
Query: 24 RRLEEVRGDLQV------QISAAQNQVKRLR-DSQRLENMDRLLKGRAQVQAEIEELQEQ 76
R L E GD+ + +SA Q V + S + EN+ R A + +EEL+
Sbjct: 1497 RALLEQTGDMSLLSNLEGAVSANQCSVDEVFCSSLQEENLTRKETPSAPAKG-VEELESL 1555
Query: 77 TRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLDRVTCHFDNQLVRN 136
+ +++ E ++ S G + +++ I+ ++L ++ + C L N
Sbjct: 1556 CEVYRQSLEKLEEKM-------ESQGIMKNKE--IQELEQLLSSERQELDCLRKQYLSEN 1606
Query: 137 AALREELDLLRIDRNRYLNVDRK----LKKEIHHLHHLVSTLILSSTSAYAVREEAKAKM 192
+++L + ++ L ++K L E+ + L LSS S + E
Sbjct: 1607 EQWQQKLTSVTLEMESKLAAEKKQTEQLSLELEVARLQLQGLDLSSRSLLGIDTE----- 1661
Query: 193 GLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPDVLEKREKQAGEVA 252
++ R E + E ++ +R H +H ++ + D Q D ++ ++ + G V
Sbjct: 1662 DAIQGRNESCDISKEHTSETTERTPKH--DVH---QICDKDAQQDLNLDIEKITETGAVK 1716
Query: 253 EGVWKTSQERLVLCYE----DALNKLSQLMGE---SDPDLLVQKYLEIEERNFAEFNF-- 303
+ ++ YE D S+ + E S P+ LV + +
Sbjct: 1717 PTGECSGEQSPDTNYEPPGEDKTQGSSECISELSFSGPNALVPMDFLGNQEDIHNLQLRV 1776
Query: 304 --INEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLE 361
+ +NL L HV E+ E+L++ D + LQE Q + ++ L+
Sbjct: 1777 KETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELK 1836
Query: 362 ARFQDVRGQLEKLKADIQLLFTKAHCDSSMIDDL 395
D+ +LE D Q L + + DL
Sbjct: 1837 KENSDLSEKLEYFSCDHQELLQRVETSEGLNSDL 1870
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 68.9 bits (167), Expect = 1e-11
Identities = 78/403 (19%), Positives = 182/403 (45%), Gaps = 47/403 (11%)
Query: 4 ERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQV------------------K 45
E+ +E ++I +Q E++RR EE+ + + ++ + + +
Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 377
Query: 46 RLRDSQRL----ENMDRLLKGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSP 101
++R + + E R L+ + Q +I E QE+ R +++I+E E R +K R
Sbjct: 378 KMRRQEEMMWEKEEKIRELEEKMHEQEKIRE-QEEKRQEEEKIREQEKRQEQEAKMWRQE 436
Query: 102 GFILDQKVKIRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLK 161
I +Q+ KIR + + + Q +++ + + +R R+E + + + ++ ++
Sbjct: 437 EKIREQEEKIREQEKKMWRQEEKI---HEQEKIREEEKRQEQEEMWRQEEK-IHEQEEIW 492
Query: 162 KEIHHLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEM--EAQVLQRQILH 219
++ +H + + E+ + + +RE+ EK Q E E + + R+
Sbjct: 493 RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREE-- 550
Query: 220 LEQLHHFLKL-KNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLM 278
E++H K+ + RQ D + ++E++ E E VW+ QE + E+ + + M
Sbjct: 551 -EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWR--QEEKIREQEEKRQEQEEKM 607
Query: 279 GESDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLL 338
+ + +K E EE+ I EQ ++ +E+I+E +E +Q
Sbjct: 608 WKQE-----EKIREQEEK-------IQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Query: 339 QEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEKLKADIQLL 381
+Q++ +Q++ + + + E++ + + +R Q EK++ +++
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMM 698
Score = 63.9 bits (154), Expect = 5e-10
Identities = 68/379 (17%), Positives = 171/379 (45%), Gaps = 35/379 (9%)
Query: 1 MEGERRAYSKEVHQRINKQLEEIRRLEEVRGD---LQVQISAAQNQVKRLRDSQRL-ENM 56
M E+ +E+ +++++Q E+IR EE R + ++ Q + + K R +++ E
Sbjct: 385 MMWEKEEKIRELEEKMHEQ-EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 443
Query: 57 DRLLKGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIR 116
+++ + ++ + E++ EQ + +++ ++ + ++ + + I QK K+ +
Sbjct: 444 EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEE 503
Query: 117 ILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLIL 176
+ Q ++V + +RE+ + +R + + K++++
Sbjct: 504 KIRKQEEKVWRQEEK-------IREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQ 556
Query: 177 SSTSAYAVREEAKAKMGLLRERA-EKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQ 235
R+E + KM E+ E+EE E ++ +++ EQ K + R+
Sbjct: 557 EKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIRE 616
Query: 236 PDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEE 295
+ + E+ EK QE + E+ + + MGE + +K E EE
Sbjct: 617 QEEKIQEQEEKIR----------EQEEKIREQEEMTQEQEEKMGEQE-----EKMCEQEE 661
Query: 296 RNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHS 355
+ + + Q ++ +++I+E +E + ++ + ++QEQ++K+ +Q +K+
Sbjct: 662 KMQEQEETMWRQEEKIREQEKKIREQEEKI------REQEEMMQEQEEKMWEQE-EKMCE 714
Query: 356 EAERLEARFQDVRGQLEKL 374
+ E+++ + + +R Q EK+
Sbjct: 715 QEEKMQEQEEKMRRQEEKM 733
Score = 62.4 bits (150), Expect = 1e-09
Identities = 72/424 (16%), Positives = 187/424 (44%), Gaps = 62/424 (14%)
Query: 10 KEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKR----LRDSQRLENMDRLLKG--- 62
+E+ ++ K E+++ +E + ++Q+ + + +++R L Q D L K
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 63 -RAQVQAEIEE----------LQEQTRALDKQIQEWETRIFTHSKNVR-SPGFILDQKVK 110
A++QA++EE +E+ +++IQEWE +I + +R I +Q+ K
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Query: 111 IRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVD----------RKL 160
+RR+ ++ + +++ + + +R + +++ + + R+L
Sbjct: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 396
Query: 161 KKEIHHLHHL----VSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQ 216
++++H + R+E +AKM E+ ++E + + + + RQ
Sbjct: 397 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ 456
Query: 217 ILHLEQLHHFLKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTS----------------- 259
E++H K++ +++ + + + ++E++ E E +W+
Sbjct: 457 ---EEKIHEQEKIREEEKRQEQEEMWRQEEKIHE-QEEIWRQKEKMHEQEEKIRKQEEKV 512
Query: 260 --QERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEERNFAEFNFI------NEQNLEL 311
QE + E+ + + + M + + Q+ + EE E I EQ ++
Sbjct: 513 WRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKM 572
Query: 312 EHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQL 371
+E+I+E +E + +Q +++Q++ + ++ +K+ + E+++ + + +R Q
Sbjct: 573 WRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE 632
Query: 372 EKLK 375
EK++
Sbjct: 633 EKIR 636
Score = 53.9 bits (128), Expect = 5e-07
Identities = 74/386 (19%), Positives = 169/386 (43%), Gaps = 46/386 (11%)
Query: 2 EGERRA---YSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQR--LENM 56
E E++A + + + + + Q+ IR L + +LQ+ + +Q+ VK+L R + +
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 57 DRLLKGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIR 116
K +++ + + Q + D+ I+E + +
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEE------------------------LTKERD 203
Query: 117 ILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNR-YLNVDRKLKKEIHHLHHLVSTLI 175
L +L R T + +NA L+E+L L+ +++ LNV ++LK+++ L+
Sbjct: 204 ALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNV-KELKRKLERAKLLLPQQQ 262
Query: 176 LSSTSAYAVRE--EAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNND 233
L + + + +E AK+ E E ++ + + + RQ +++ ++ +
Sbjct: 263 LQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 322
Query: 234 RQPDPDVLEKREKQAGEVAEGVWKTS-----QERLVLCYEDALNKLSQLMGESDPDLLVQ 288
+ + + ++E++ E +W+ QE ++ E+ + + ++M E + +
Sbjct: 323 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-----E 377
Query: 289 KYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQ 348
K EE + + I E E H QE+I+E +E + +Q QEQ+ K+ +Q
Sbjct: 378 KMRRQEEMMWEKEEKIRELE-EKMHEQEKIREQEEKRQEEEKIR-EQEKRQEQEAKMWRQ 435
Query: 349 RMDKVHSEAERLEARFQDVRGQLEKL 374
+K+ + E++ + + + Q EK+
Sbjct: 436 E-EKIREQEEKIREQEKKMWRQEEKI 460
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 68.2 bits (165), Expect = 2e-11
Identities = 66/376 (17%), Positives = 171/376 (45%), Gaps = 22/376 (5%)
Query: 10 KEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQVQAE 69
+E+ ++ K E+++ +E + ++Q+ + + +++R + LL + Q+QAE
Sbjct: 205 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK----------LLLPQQQLQAE 254
Query: 70 IEELQEQTRALDKQIQ-EWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLDRVTCH 128
+ L ++ +++ ++Q + E + N + + Q+ KI+ R ++ Q +++
Sbjct: 255 ADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQ 314
Query: 129 FDNQLVRNAALREELDLLRIDRNRYLNVDRKLKK--EIHHLHHLVSTLILSSTSAYAVRE 186
+ + + E+ + +R + K+++ E H + +RE
Sbjct: 315 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 374
Query: 187 EAK-----AKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPDVL 241
+ K AKM E+ ++E + + +++Q Q + + + + + Q + +
Sbjct: 375 QEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKM 434
Query: 242 EKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQ--KYLEIEERNFA 299
++E++ E + + QE + E+ + + + MGE + + Q K E EE+
Sbjct: 435 RRQEEKIREQEKKI--REQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR 492
Query: 300 EFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAER 359
+ I EQ ++ +E+I+E +E + +Q +Q++ +Q++ +K+ + E+
Sbjct: 493 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 552
Query: 360 LEARFQDVRGQLEKLK 375
+ + +R Q EK++
Sbjct: 553 MREQEVRLRQQEEKMQ 568
Score = 64.3 bits (155), Expect = 3e-10
Identities = 71/368 (19%), Positives = 163/368 (44%), Gaps = 29/368 (7%)
Query: 31 GDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQVQAEI-------EELQEQTRALDKQ 83
G+L+ +SA Q K+ ++ L K R + E+ EEL+E+ L ++
Sbjct: 163 GELEQALSAVATQKKKAD-----RYIEELTKERDALSLELYRNTITDEELKEKNAKLQEK 217
Query: 84 IQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLDRVTCHFDNQLVR-NAALREE 142
+Q E+ NV+ L +K++ R ++ + + QL H +L +A L+ +
Sbjct: 218 LQLVESEKSEIQLNVKE----LKRKLE-RAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 272
Query: 143 LDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKE 202
++ + + K+ ++ + + E+ + + ++ E+ EK
Sbjct: 273 VEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKM 332
Query: 203 EAQSEMEAQVLQRQILHLEQLHHFLKLKNND--RQPDPDVLEKREKQAGEVAEGVWKTS- 259
Q EM + ++ E++H K++ + RQ + + E+ ++Q E +W+
Sbjct: 333 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK--MWRQEE 390
Query: 260 ----QERLVLCYEDALNKLSQLMGESDPDLLVQK--YLEIEERNFAEFNFINEQNLELEH 313
QE + E+ + + + MGE + + Q+ E EE+ + I EQ ++
Sbjct: 391 KIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIRE 450
Query: 314 VQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEK 373
+E+I+E +E + +Q +Q+ +Q++ +K+ + E++ + + +R Q EK
Sbjct: 451 QEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEK 510
Query: 374 LKADIQLL 381
++ +++
Sbjct: 511 IREQEEMM 518
Score = 53.5 bits (127), Expect = 6e-07
Identities = 52/286 (18%), Positives = 132/286 (46%), Gaps = 20/286 (6%)
Query: 4 ERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGR 63
ER +E ++I +Q E++RR EE+ + + ++ + + E R L+ +
Sbjct: 299 EREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM------WEKEEKIRELEEK 352
Query: 64 AQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLD 123
Q +I E QE+ R +++I+E E R +K R I +Q+ KIR + +++ Q +
Sbjct: 353 MHEQEKIRE-QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEE 411
Query: 124 RVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSAYA 183
++ + + ++E+ + +R + ++K++++ + +
Sbjct: 412 KMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM--------- 462
Query: 184 VREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPDVLEK 243
+E + KMG + ++EA+ + + + ++RQ + + ++ + + +++++
Sbjct: 463 --QEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 520
Query: 244 REKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQK 289
+E++ E E + QE + E+ + + + M E + L Q+
Sbjct: 521 QEEKMWEQEEKM--CEQEEKMQEQEEKMRRQEEKMREQEVRLRQQE 564
Score = 36.6 bits (83), Expect = 0.077
Identities = 28/163 (17%), Positives = 78/163 (47%), Gaps = 15/163 (9%)
Query: 3 GERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRD--SQRLENMDRLL 60
GE+ E + + +Q E++RR EE + + +I + +++ + ++ E M
Sbjct: 414 GEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQE 473
Query: 61 KGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILEN 120
+ +A+++E +E+ R +++I+E E + I +Q+ KIR + +++
Sbjct: 474 GKMCEQEAKMQEQEEKMRRQEEKIREQEKK-------------IREQEEKIREQEEMMQE 520
Query: 121 QLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKE 163
Q +++ + + ++E+ + +R + + +L+++
Sbjct: 521 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQ 563
Score = 34.7 bits (78), Expect = 0.29
Identities = 14/75 (18%), Positives = 43/75 (57%)
Query: 310 ELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRG 369
E +H+ +E++ + L + + + L +QQ++ + ++ +K+ E+++ + + +R
Sbjct: 254 EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIRE 313
Query: 370 QLEKLKADIQLLFTK 384
Q EK++ ++++ K
Sbjct: 314 QEEKMRRQEEMMWEK 328
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 67.0 bits (162), Expect = 5e-11
Identities = 98/413 (23%), Positives = 182/413 (44%), Gaps = 49/413 (11%)
Query: 10 KEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQVQAE 69
KE+ + +K+ +I LE+ LQ ++ +++ RL++ + D L + +Q
Sbjct: 1025 KEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQL 1084
Query: 70 IEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLDRVTCHF 129
EELQE+ LD QIQ S+ + + K KI+ ILE Q +V C
Sbjct: 1085 KEELQEKNVTLDVQIQHVVEGKRALSELTQG---VTCYKAKIKELETILETQ--KVECSH 1139
Query: 130 DNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSAYAVREEAK 189
+L ++ L +E +L+++RN LK+ HL V + ++EE
Sbjct: 1140 SAKLEQD-ILEKESIILKLERN--------LKEFQEHLQDSVKNTKDLNVKELKLKEEIT 1190
Query: 190 ------AKMGLLRERAEKEEAQSEMEAQVLQRQI----LHLEQLHHFLKLKNNDRQPDPD 239
M L + E+EE + E + L+ ++ + L L+ K D +
Sbjct: 1191 QLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKE 1250
Query: 240 VLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEERNFA 299
L +KQ +V + V E +L + +N+L + + + L++++R
Sbjct: 1251 KLTDAKKQIKQVQKEVSVMRDEDKLLRIK--INELEKKKNQCSQE------LDMKQRTIQ 1302
Query: 300 EF-NFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAE 358
+ +N Q +E E +Q+ + ++ V + +D + L+EQ+Q ++Q D+V
Sbjct: 1303 QLKEQLNNQKVE-EAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQ--DQV----- 1354
Query: 359 RLEARFQDVR---GQLEKLKADIQLLFTK----AHCDSSMIDDLLGVKTSMGD 404
LEA+ ++V +LEK K L TK ++ + D+LG T++ D
Sbjct: 1355 -LEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQD 1406
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 67.0 bits (162), Expect = 5e-11
Identities = 71/364 (19%), Positives = 152/364 (41%), Gaps = 46/364 (12%)
Query: 9 SKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQVQA 68
+KE +RI + E+ +++ ++ + A Q ++L+ + L + LK +Q
Sbjct: 1447 AKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAA--LISRKEALKENKSLQE 1504
Query: 69 EIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLDRVTCH 128
E+ + L K + + E+++ +K +K + R+ +L+ + D++
Sbjct: 1505 ELSLARGTIERLTKSLADVESQVSAQNK----------EKDTVLGRLALLQEERDKLITE 1554
Query: 129 FDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSAYAVREEA 188
D L+ N +L + L++ KL KEI L S+ I ST +E
Sbjct: 1555 MDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLK---SSKIAESTEWQEKHKEL 1611
Query: 189 KAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPDVLEKREKQA 248
+ + +L + E ++E V++ ++L+ L+ +++ L++ E++
Sbjct: 1612 QKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEM 1671
Query: 249 GEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEERNFAEFNFINEQN 308
E+ E + K ++ + QK LE+EE N +
Sbjct: 1672 EEMKEKMRKFAKSKQ------------------------QKILELEEEN-------DRLR 1700
Query: 309 LELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLEARFQDVR 368
E+ + KE E L+S+ AS ++ + + + L ++ + SE + L QD++
Sbjct: 1701 AEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLK 1760
Query: 369 GQLE 372
Q+E
Sbjct: 1761 HQIE 1764
Score = 57.0 bits (136), Expect = 6e-08
Identities = 126/596 (21%), Positives = 234/596 (39%), Gaps = 86/596 (14%)
Query: 4 ERRAYSKEVHQRINKQLEEIRRLEEVRGDLQ----------VQISAAQNQVKRLRDSQRL 53
E+ +E NK EEIR L DL +Q NQV ++DSQ+
Sbjct: 2493 EKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQK 2552
Query: 54 ENMDRLLKGRAQVQ---AEIEE------------------LQEQTRALDKQIQEWETRIF 92
+ ++ L+ +++ A++EE LQE+ + L K+I+ + I
Sbjct: 2553 QLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSIS 2612
Query: 93 THSKNVRSPGFILDQKVKI---RRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRID 149
++ V + L ++ + ++++ E ++ R++ F + R A L EEL ++ +
Sbjct: 2613 QLTRQVTA----LQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKE 2668
Query: 150 RNRYLN-VDRKLKKEIHHLHHLV-----STLILSSTSAYAVREEAKAKMGLLRERAEKEE 203
+ + ++ KLKKE+ HLHH T A R+ + + LL E +
Sbjct: 2669 AAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKG 2728
Query: 204 AQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPDVLE----------KREKQA--GEV 251
+++++ L + H +L R+ D + E RE+ A E
Sbjct: 2729 LTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSET 2788
Query: 252 AEGVWKTSQERLVLCYEDALNKLSQLMGESDPDL------LVQKYLEIEERNFAEFNFIN 305
A + T + L L KL+Q + D L L Y +++ + A + N
Sbjct: 2789 AFSMNSTEENSL-----SHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQN 2843
Query: 306 EQN---LELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLEA 362
E++ ELE ++ + Q + S + L++ LQ D++ E + L+
Sbjct: 2844 ERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSS-LQNDRDRLLKELKNLQQ 2902
Query: 363 RFQDVR---GQLEKLKADIQLLFTKAHCDSSMIDDLLGVKTSMGDRDMGLFLSLIEKRLV 419
++ + +L LKA +Q K M ++L S L + +
Sbjct: 2903 QYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEIH 2962
Query: 420 ELLTVQAFLHAQSFTSLADAALLVLGQSLEDLPKKMAPLQ-------PPDTLEDPPGFEA 472
E + +L A S + L L + L + PL+ P+T P G
Sbjct: 2963 ERRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPDG--- 3019
Query: 473 SDDYPMSREELLSQV-EKLVEL-QEQAEAQRQKDLAAAAAKLDGTLSVDLASTQRA 526
S + E L +Q+ + L E+ Q++ Q+ + + TLS+ L T ++
Sbjct: 3020 SQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQS 3075
Score = 49.3 bits (116), Expect = 1e-05
Identities = 83/422 (19%), Positives = 181/422 (42%), Gaps = 63/422 (14%)
Query: 11 EVHQRINKQLEEIRRLEEVRGD-------LQVQISAAQNQVKRLRDSQRLE-NMDRLLKG 62
++ ++INKQ EI L+ V + LQ ++ ++Q Q+ L + L+ +D L K
Sbjct: 1341 QLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKL 1400
Query: 63 RAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIR-RRIRILENQ 121
++ + ++ L Q + + + +T I +++ L+ + K RI+ L+ +
Sbjct: 1401 ISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVE 1460
Query: 122 LDRVTC---HFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIH----HLHHLVSTL 174
L + + ++ +L I R L ++ L++E+ + L +L
Sbjct: 1461 LCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSL 1520
Query: 175 ILSSTSAYAVREEAKAKMG---LLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKN 231
+ A +E +G LL+E E+++ +EM+ +L+ Q L L L+
Sbjct: 1521 ADVESQVSAQNKEKDTVLGRLALLQE--ERDKLITEMDRSLLENQSLSSSCESLKLALEG 1578
Query: 232 NDRQPDPDVLEKREKQAGEVAEGV-WKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKY 290
+ V E ++ ++AE W+ + L YE +L+Q Y
Sbjct: 1579 LTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYE----------------ILLQSY 1622
Query: 291 LEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARAS-----KDDQHLLQEQQQKV 345
+ N AE ++HV E +++ ++ L S K+ + LQE +Q+
Sbjct: 1623 ENVS--NEAE---------RIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQE- 1670
Query: 346 LQQRMDKVHSEAERLEARFQDVRGQLEKLKADI--------QLLFTKAHCDSSMIDDLLG 397
+++ +K+ A+ + + ++ + ++L+A++ + + T ++SM ++L
Sbjct: 1671 MEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELER 1730
Query: 398 VK 399
VK
Sbjct: 1731 VK 1732
Score = 48.9 bits (115), Expect = 2e-05
Identities = 107/530 (20%), Positives = 223/530 (42%), Gaps = 52/530 (9%)
Query: 9 SKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQVQA 68
+KE+ +N+ +EE ++ + +S ++Q+ L + L + L Q++
Sbjct: 715 AKEI-SNLNQLIEEFKKNADNNSSAFTALSEERDQL--LSQVKELSMVTELRAQVKQLEM 771
Query: 69 EIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLDRVTCH 128
+ E + Q R LD + Q + T + S ++ K K +I +L+N+LD V
Sbjct: 772 NLAEAERQRR-LDYESQTAHDNLLTEQIHSLS----IEAKSK-DVKIEVLQNELDDVQLQ 825
Query: 129 FDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSAYAVREEA 188
F Q +L+ +L + R + ++ L +S L T + E
Sbjct: 826 FSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEK 885
Query: 189 KAKMGLLRERAEKEEAQ-SEMEAQVLQRQI-LHLEQLHHFLKLKNNDRQPD-----PDVL 241
K + L++ E+++ Q +E+ + ++ + L+ E+ +++K Q + +
Sbjct: 886 KRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAK 945
Query: 242 EKREKQAGEVAEGV----------WKTSQERL-----VLCYEDALNKLSQLMGESDPDLL 286
+++ ++ EV+ G+ + S+E L +L E+ K + L
Sbjct: 946 KEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKEL 1005
Query: 287 VQKYLEIEERNFAEFNFINEQNLELEHVQ-------EEIKEMQEALVSARASKDDQHLLQ 339
+Q+ +EE A +++ + L + +E KE E V+++ + + +L Q
Sbjct: 1006 LQRVSRLEE-ELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQ 1064
Query: 340 EQQQKVLQ-QRMDKVHSEAERLEARFQDVRGQLEKLKAD----IQLLFTKAHCDSSMIDD 394
+K ++ Q + K E E +FQ + Q+ + D I LL + + ++I
Sbjct: 1065 TISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQK 1124
Query: 395 LLGVKTSMGDRDMGLFLSLIEKRLVELLTVQAFLHAQSFTSLADAALLVLGQSLEDLPKK 454
L+ T D D ++L+++ +V ++ ++ + + +L L + E L KK
Sbjct: 1125 LITSNTDASDGDS---VALVKETVV--ISPPCTGSSEHWKPELEEKILALEKEKEQLQKK 1179
Query: 455 MAPLQPPDTLEDPPGFEASDDYPMSREELLSQVEKLVELQEQAEAQRQKD 504
LQ T +A + REEL Q + LQEQ + Q +++
Sbjct: 1180 ---LQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKEN 1226
Score = 48.1 bits (113), Expect = 3e-05
Identities = 110/549 (20%), Positives = 226/549 (41%), Gaps = 79/549 (14%)
Query: 5 RRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRA 64
R E+HQ + + + D+Q +++ A+ V L+D R +++
Sbjct: 27 RAPLDPELHQESDMEFNNT-----TQEDVQERLAYAEQLVVELKDIIRQKDV-------- 73
Query: 65 QVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLDR 124
Q+Q + E LQE+ +A D +I+ + ++ +K +I + K + + ++
Sbjct: 74 QLQQKDEALQEERKAADNKIK--KLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQSEEQ 131
Query: 125 VTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSAYAV 184
++ H ++ EE+++ K+K ++ L+STL T A A
Sbjct: 132 LSKH------DKSSTEEEMEI------------EKIKHKLQEKEELISTLQAQLTQAQAE 173
Query: 185 R-----EEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPD 239
+ E + + + ++ EKEE S ++AQ+ Q Q Q ++ D + +
Sbjct: 174 QPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQ----QVVREKDARFETQ 229
Query: 240 VLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQ-LMGESD-PDLLVQKYLEIEERN 297
V ++ V + +T ++ + + L + + L+G + DLL Q+ E+RN
Sbjct: 230 VRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRN 289
Query: 298 FAEFNFINEQNLE-------LEHVQEEIKEMQEAL-VSARASKDDQHLLQEQQQKVLQQR 349
+ + E +E +EE K + E + + K H LQE+ +L+Q
Sbjct: 290 QILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQF 349
Query: 350 MDKVHSEAERLEARFQDVRGQLEKLKADIQLLFTKAHCDSSMIDDLLGVKTSMGDRDMGL 409
++AE LE+R+ + +K KA+++ + +L ++ D++
Sbjct: 350 EQAGQAQAE-LESRYSALE---QKHKAEMEEKTSHILSLQKTGQELQSACDALKDQN--- 402
Query: 410 FLSLIEKRLVELLTVQAFLHAQSFTSLADAALLVLGQSLEDLPK--KMAPLQPPDTLEDP 467
+L++ QA AQ+ L D L Q +++ + PLQ +T
Sbjct: 403 ------SKLLQDKNEQAVQSAQTIQQLEDQ----LQQKSKEISQFLNRLPLQQHETASQT 452
Query: 468 --PGFEASDDYPMSREELLSQVEKLVELQEQAEAQ-----RQKDLAAAAAKLDGTLSVDL 520
P ++ E + S +++VEL+ + A ++L A KL +++ L
Sbjct: 453 SFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITL-L 511
Query: 521 ASTQRAGSS 529
+ R G +
Sbjct: 512 EAQNRTGEA 520
Score = 47.4 bits (111), Expect = 4e-05
Identities = 83/392 (21%), Positives = 157/392 (40%), Gaps = 64/392 (16%)
Query: 18 KQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQVQAEI----EEL 73
+QLEE + D +Q +AA+N + +MD L A++ AE+ E+L
Sbjct: 2481 QQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDL 2540
Query: 74 QEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVK--------IRRRIRILENQLDRV 125
+ D Q ++ +K + + L++K+K +RR L+ + +
Sbjct: 2541 NQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDL 2600
Query: 126 TCHFDNQLVRNAALREELDLLRIDRNRYL-NVDRKLK-KEIHHLHHLVST----LILSST 179
+ ++ V + L ++ L+ + L + K+K +E+H L L S+ +
Sbjct: 2601 SKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEE 2660
Query: 180 SAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPD 239
V++EA K+G + ++ +KE L+ LHH + N+
Sbjct: 2661 ELVCVQKEAAKKVGEIEDKLKKE-----------------LKHLHHDAGIMRNE------ 2697
Query: 240 VLEKREKQAGEVAEGVWKTSQERLVLCYED-ALNKLSQLMGESDPDLLVQKYLEIEERNF 298
E E++ E+A + + Q+ L++ E+ L Q G S L
Sbjct: 2698 -TETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQ------------ 2744
Query: 299 AEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAE 358
N + N EL +E+K +A + A +Q LL ++ +L + ++S E
Sbjct: 2745 ---NSRDHANEEL----DELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEE 2797
Query: 359 RLEARFQDVRGQLEKLKADIQLLFTKAHCDSS 390
+ + + QL L D QLL + + S
Sbjct: 2798 NSLSHLEKLNQQL--LSKDEQLLHLSSQLEDS 2827
Score = 42.7 bits (99), Expect = 0.001
Identities = 108/600 (18%), Positives = 239/600 (39%), Gaps = 108/600 (18%)
Query: 2 EGERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLR----DSQR----- 52
E ++++KE+ + + ++ +E+++L++ Q +ISA + VK L +SQ+
Sbjct: 2000 EPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEIT 2059
Query: 53 LENMDRLLKGRAQVQAEI------------------------------------EELQEQ 76
EN+ + ++ R + QAE+ +++++
Sbjct: 2060 KENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQK 2119
Query: 77 TRALDKQIQEWETRIFTHSKNVRSP-GFILDQKVKIRRRIRIL-------ENQLDRVTCH 128
L++++++ E + KN++ + +KV + I + + ++ ++ +
Sbjct: 2120 DEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEN 2179
Query: 129 FDNQLVRNAALREELDLLRIDRNRYLNVDRKLKK-----------EIHHLHHLVSTLILS 177
D+ + + AA + + L+ DR+R ++ +K ++ EI S L
Sbjct: 2180 LDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQ 2239
Query: 178 STSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQR-----------QILHLEQLHHF 226
EE K + L + E++++ E Q+ Q+ + LE+ H
Sbjct: 2240 LRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHL 2299
Query: 227 LKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQER-----LVLCYEDALNKLSQLMGES 281
N+ L+ + Q +++ + K +++ ++ E + +
Sbjct: 2300 YHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQL 2359
Query: 282 DPDLLVQKYLEI---EERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLL 338
+ DL + L EE N E I+ + + E +Q I E+++ + K+ ++LL
Sbjct: 2360 ETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQ--HDKEIKELENLL 2417
Query: 339 QEQQQK--VLQQRMDKVHSEAERLEARFQDVRGQLEKLKADIQLLFTKAHCDSSMIDDLL 396
+++++ VL++ K + +L + ++ + + KA + F K+ SS+ +D
Sbjct: 2418 SQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLD-SFVKSM--SSLQND-- 2472
Query: 397 GVKTSMGDRDMGLFLSLIEKRLVELLTVQAFLHAQSFTSLADAALLVLGQSLEDLPKKMA 456
DR +G + L E+ L L A A L + + L M
Sbjct: 2473 ------RDRIVGDYQQLEERHL------SIILEKDQLIQEAAAENNKLKEEIRGLRSHMD 2520
Query: 457 PLQPPDTLEDPPGFEASDDYPMSREELLSQVEKLVELQEQAEAQRQKDLAAAAAKLDGTL 516
L + D + +D SQ ++L+E+Q Q+ K+L AKL+ L
Sbjct: 2521 DLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQ----LQQNKELENKYAKLEEKL 2576
Score = 42.0 bits (97), Expect = 0.002
Identities = 84/387 (21%), Positives = 150/387 (38%), Gaps = 74/387 (19%)
Query: 22 EIRRLEEVRGDLQVQISAAQNQVKRLRDSQR-LENMDRLLKGRAQV----QAEIEELQEQ 76
++R E+ L Q ++LR QR LE + L GRAQV Q E+ +++
Sbjct: 229 QVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQR 288
Query: 77 TRALDKQIQEWETRIFTHSKNV---RSPGFILDQKVKIRRRIRILE-NQLDRVTCHFDNQ 132
+ L +Q+Q+ E T V R IL +K+++ R L + L H Q
Sbjct: 289 NQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQ 348
Query: 133 LVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSAYAVREEAKAKM 192
+ + EL+ +RY +++K K E+ + +L + + + K +
Sbjct: 349 FEQAGQAQAELE------SRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQN 402
Query: 193 GLLRERAEKEEAQSEMEAQVLQRQILH----LEQLHHFLKLKNNDRQPD---PDV----- 240
L + ++ QS Q L+ Q+ + Q + L L+ ++ PDV
Sbjct: 403 SKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGT 462
Query: 241 ----------LEKR----EKQAGEV-----------AEGVWKTSQERLV----------- 264
L+KR E + G + AE +SQ L+
Sbjct: 463 QAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADR 522
Query: 265 ----LCYEDALNKLSQLMGESDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKE 320
+ D NK S ES D+L + + + ++ LE++ QEEI
Sbjct: 523 EVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKE-------LSVLLLEMKEAQEEIAF 575
Query: 321 MQEALVSARASKDDQHLLQEQQQKVLQ 347
++ L RA + D +L +++ K ++
Sbjct: 576 LKLQLQGKRAEEADHEVLDQKEMKQME 602
Score = 38.1 bits (87), Expect = 0.027
Identities = 64/376 (17%), Positives = 164/376 (43%), Gaps = 51/376 (13%)
Query: 15 RINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQVQAEIEELQ 74
+I QL+EI E + +L++++S+ +++ +++ E + +L + + EIE L+
Sbjct: 1306 QIKAQLKEI---EAEKVELELKVSSTTSEL-----TKKSEEVFQLQEQINKQGLEIESLK 1357
Query: 75 EQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLDRVTCHFDNQLV 134
+ + + + ++ + + + + + K+ +++ + + V+
Sbjct: 1358 TVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSE 1417
Query: 135 RNAALR-------EELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSAYAVREE 187
+ AAL E+ DL++ + ++ + K+ + L L + EE
Sbjct: 1418 KEAALTKIQTEIIEQEDLIKA---LHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEE 1474
Query: 188 AKAKMGLLRERAEKEEAQSEMEAQVLQRQ--ILHLEQLHHFLKLKNNDRQPDPDVLEKRE 245
++AK ++ Q +++A ++ R+ + + L L L +E+
Sbjct: 1475 SRAK----------QQIQRKLQAALISRKEALKENKSLQEELSLARG-------TIERLT 1517
Query: 246 KQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEERNFAEFNFIN 305
K +V V ++E+ + L +L+ L E D + +E ++ + +
Sbjct: 1518 KSLADVESQVSAQNKEK-----DTVLGRLALLQEERDKLITEMDRSLLENQSLS--SSCE 1570
Query: 306 EQNLELEHVQEEIKEMQEALVSARASK-------DDQHLLQEQQQKVLQQRMDKVHSEAE 358
L LE + E+ +++ + + S ++SK ++H +++ ++L Q + V +EAE
Sbjct: 1571 SLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAE 1630
Query: 359 RLEARFQDVRGQLEKL 374
R++ + VR + ++L
Sbjct: 1631 RIQHVVEAVRQEKQEL 1646
Score = 30.4 bits (67), Expect = 5.5
Identities = 57/335 (17%), Positives = 130/335 (38%), Gaps = 43/335 (12%)
Query: 2 EGERRAYSKE-VHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLL 60
E ER + E V Q + ++R E + + + Q+ A+ +++ ++ E M +
Sbjct: 1628 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMK-----EKMRKFA 1682
Query: 61 KGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILEN 120
K + Q E+EE ++ RA E T + + + +L ++ + ++
Sbjct: 1683 KSKQQKILELEEENDRLRA------EVHPAGDTAKECMET---LLSSNASMKEELERVKM 1733
Query: 121 QLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTS 180
+ + ++ F + + +L EE+ L+ NV ++ E H + + T
Sbjct: 1734 EYETLSKKFQSLMSEKDSLSEEVQDLKHQIEG--NVSKQANLEATEKHDNQTNVTEEGTQ 1791
Query: 181 AYAVREEAKAKMGLLRERAEKEEAQSEMEAQ-VLQRQILHLEQLHHFLKLKNNDRQPDPD 239
+ E + + + E S A + + ++++++L+
Sbjct: 1792 SIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQ----------Q 1841
Query: 240 VLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEERNFA 299
+ + +E+ AG E K + E+ N L + D +L ++ +
Sbjct: 1842 IDQLKERIAGLEEE---KQKNKEFSQTLENEKNTLLSQISTKDGEL------KMLQEEVT 1892
Query: 300 EFNFINEQNLELEHVQEEIKEMQEALVSARASKDD 334
+ N +N+Q +QEE+ + + +A KDD
Sbjct: 1893 KMNLLNQQ------IQEELSRVTKLKETAEEEKDD 1921
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 66.6 bits (161), Expect = 7e-11
Identities = 108/553 (19%), Positives = 236/553 (42%), Gaps = 62/553 (11%)
Query: 1 MEGERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLL 60
ME + ++SK + + E ++E++R D Q +I QNQ +DS+R + +
Sbjct: 592 MEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQ----QDSERAAHAKEME 647
Query: 61 KGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILEN 120
RA++ I+E + A+ ++ + E + ++ + + KVK ++ N
Sbjct: 648 ALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCN 707
Query: 121 QLDRVTCHFDNQL------------VRNAA---------LREELDL-------LRIDRNR 152
+ +V +F +QL +R A+ LR++L+ L I++N
Sbjct: 708 EQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNA 767
Query: 153 YLNVDRKLKKEIHHLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQV 212
+ + +E+ ++ L + + V+E + ++ +L+E+ + ++ +
Sbjct: 768 ESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRS 827
Query: 213 LQRQILHLEQLHHFLKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALN 272
+Q + L Q + ++D + + L E + E E +E+L+ E N
Sbjct: 828 MQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDE-----REEQLIKAKEKLEN 882
Query: 273 KLSQLM---GESDPDLL-VQKYLEIEERNFAEFNF-INEQNLELEHVQEEIKEM----QE 323
++++M G++ L + L ++ER+ E + + N +Q+ I++M ++
Sbjct: 883 DIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQ 942
Query: 324 ALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEKLKADIQLLFT 383
+ A +++ E++ L+++M+ H++ + L+AR++ + + +I
Sbjct: 943 SQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQ 1002
Query: 384 KAHCDSSMIDDLLGVKTSMGDRDMGLFLSL--IEKRLVELLTVQAFLHAQSFTSLADAAL 441
K D+ D L G + + + GL L + K+ + Q A
Sbjct: 1003 KTLLDTE--DKLKGAR----EENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEK 1056
Query: 442 LVLGQSLEDLPKKMAPLQPP-DTLEDPPGFEASDDYPMSREEL------LSQVEKLVELQ 494
SLED + A LQ DTL++ + ++ S+E L + + K +E
Sbjct: 1057 TETLASLEDTKQTNAKLQNELDTLKE-NNLKNVEELNKSKELLTVENQKMEEFRKEIETL 1115
Query: 495 EQAEAQRQKDLAA 507
+QA AQ+ + L+A
Sbjct: 1116 KQAAAQKSQQLSA 1128
Score = 33.9 bits (76), Expect = 0.50
Identities = 108/533 (20%), Positives = 206/533 (38%), Gaps = 95/533 (17%)
Query: 10 KEVHQRINKQLEE--IRRLEEVR-----GDLQVQISAAQNQVKRLRDSQRLENMDRLLKG 62
KE Q I + L E + R E + G+++ +++ A++ D LE ++ +
Sbjct: 358 KEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDG----HDQHVLELEAKMDQL 413
Query: 63 RAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQL 122
R V+A E E L+++ ++ E F + + G + V + RI LE L
Sbjct: 414 RTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDL 473
Query: 123 DRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSAY 182
++ A LR L+ + + +++ L +EI L +
Sbjct: 474 AL-------RVQEVAELRRRLESNKPAGD--VDMSLSLLQEISSLQEKLEV--------- 515
Query: 183 AVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPDVLE 242
R + + ++ L+E E + E + L L + + LK K LE
Sbjct: 516 -TRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSK----------LE 564
Query: 243 KREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEERNFAEF- 301
K+ +V +WK+ E + ++ A+ +L + K L E FAE
Sbjct: 565 HANKENSDVI-ALWKSKLETAIASHQQAMEELK---------VSFSKGLGTETAEFAELK 614
Query: 302 ---------------NFINEQNLE-LEHVQEE----------IKEMQEALVSARASKD-- 333
N N+Q+ E H +E IKE + +L + R+ D
Sbjct: 615 TQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKA 674
Query: 334 -DQHLLQ-EQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEKLKADIQLLFTKAHCDSSM 391
DQHL++ E LQ+ KV E E L+A+ + ++ + + KA + +
Sbjct: 675 EDQHLVEMEDTLNKLQEAEIKV-KELEVLQAKCNEQTKVIDNFTSQL-----KATEEKLL 728
Query: 392 IDDLLGVKTSMGDRDMGLFLSLIE--KRLVELLTVQAFLHAQSFTSLA------DAALLV 443
D L +S G +M +E ++ ++ L ++ + +S+ + L
Sbjct: 729 DLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTN 788
Query: 444 LGQSLEDLPKKMAPLQPPDTLEDPPGFEASDDYPMSREELLSQVEKLVELQEQ 496
L ++L ++ + L+ + EAS++ + + V KL + +EQ
Sbjct: 789 LQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQ 841
Score = 32.7 bits (73), Expect = 1.1
Identities = 37/233 (15%), Positives = 89/233 (38%), Gaps = 12/233 (5%)
Query: 9 SKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQVQA 68
+K+ + ++ +L+ ++ ++ ++ S V+ + + + ++ L + AQ
Sbjct: 1066 TKQTNAKLQNELDTLKE-NNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQ 1124
Query: 69 EIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLDRVTCH 128
++ LQE+ L +++ + +H K + +Q +++++R D
Sbjct: 1125 QLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKAS 1184
Query: 129 FDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSAYAV---- 184
+ +AL E D + V R LH +V TL
Sbjct: 1185 LQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNL 1244
Query: 185 -------REEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLK 230
+ + + G +A+++E E + L I+ L++ + LK+K
Sbjct: 1245 ELQLKENKRQLSSSSGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLKMK 1297
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 66.6 bits (161), Expect = 7e-11
Identities = 108/553 (19%), Positives = 236/553 (42%), Gaps = 62/553 (11%)
Query: 1 MEGERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLL 60
ME + ++SK + + E ++E++R D Q +I QNQ +DS+R + +
Sbjct: 627 MEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQ----QDSERAAHAKEME 682
Query: 61 KGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILEN 120
RA++ I+E + A+ ++ + E + ++ + + KVK ++ N
Sbjct: 683 ALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCN 742
Query: 121 QLDRVTCHFDNQL------------VRNAA---------LREELDL-------LRIDRNR 152
+ +V +F +QL +R A+ LR++L+ L I++N
Sbjct: 743 EQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNA 802
Query: 153 YLNVDRKLKKEIHHLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQV 212
+ + +E+ ++ L + + V+E + ++ +L+E+ + ++ +
Sbjct: 803 ESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRS 862
Query: 213 LQRQILHLEQLHHFLKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALN 272
+Q + L Q + ++D + + L E + E E +E+L+ E N
Sbjct: 863 MQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDE-----REEQLIKAKEKLEN 917
Query: 273 KLSQLM---GESDPDLL-VQKYLEIEERNFAEFNF-INEQNLELEHVQEEIKEM----QE 323
++++M G++ L + L ++ER+ E + + N +Q+ I++M ++
Sbjct: 918 DIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQ 977
Query: 324 ALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEKLKADIQLLFT 383
+ A +++ E++ L+++M+ H++ + L+AR++ + + +I
Sbjct: 978 SQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQ 1037
Query: 384 KAHCDSSMIDDLLGVKTSMGDRDMGLFLSL--IEKRLVELLTVQAFLHAQSFTSLADAAL 441
K D+ D L G + + + GL L + K+ + Q A
Sbjct: 1038 KTLLDTE--DKLKGAR----EENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEK 1091
Query: 442 LVLGQSLEDLPKKMAPLQPP-DTLEDPPGFEASDDYPMSREEL------LSQVEKLVELQ 494
SLED + A LQ DTL++ + ++ S+E L + + K +E
Sbjct: 1092 TETLASLEDTKQTNAKLQNELDTLKE-NNLKNVEELNKSKELLTVENQKMEEFRKEIETL 1150
Query: 495 EQAEAQRQKDLAA 507
+QA AQ+ + L+A
Sbjct: 1151 KQAAAQKSQQLSA 1163
Score = 38.1 bits (87), Expect = 0.027
Identities = 104/520 (20%), Positives = 207/520 (39%), Gaps = 92/520 (17%)
Query: 7 AYSKEVHQRINKQLEEIRRLEEV----------RGDLQVQISAAQNQVKRLRDSQRLENM 56
A +E + +N+ EE R++E++ +GDL+ Q ++K L S E
Sbjct: 419 AADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARIKELEQSLLFE-- 476
Query: 57 DRLLKGRA-QVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRI 115
K +A ++Q E+E+ + T + +I E E + + V ++RRR
Sbjct: 477 ----KTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEV----------AELRRR- 521
Query: 116 RILENQLDRVTCHFDNQLVRN-AALREELDLLRIDRNRYLNVDRK---LKKEIHHLHHLV 171
LE+ L++ ++L+E+L++ R D R + ++ ++E H +
Sbjct: 522 --LESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKE--I 577
Query: 172 STLILSSTSAYAVREEAKAKMGLLRERAEKEEA------QSEMEAQVLQRQILHLEQLHH 225
L ++ E K+K+ E A KE + +S++E + Q E
Sbjct: 578 KALYTATEKLSKENESLKSKL----EHANKENSDVIALWKSKLETAIASHQQAMEELKVS 633
Query: 226 FLKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDL 285
F K + E AE KT E++ L Y+ +++ L + D +
Sbjct: 634 FSKGLGTE--------------TAEFAE--LKTQIEKMRLDYQ---HEIENLQNQQDSER 674
Query: 286 LVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQ-EQQQK 344
E+E I E+ LE ++ ++ + + DQHL++ E
Sbjct: 675 AAHAK-EMEALRAKLMKVIKEKENSLEAIRSKLDKAE-----------DQHLVEMEDTLN 722
Query: 345 VLQQRMDKVHSEAERLEARFQDVRGQLEKLKADIQLLFTKAHCDSSMIDDLLGVKTSMGD 404
LQ+ KV E E L+A+ + ++ + + KA + + D L +S G
Sbjct: 723 KLQEAEIKV-KELEVLQAKCNEQTKVIDNFTSQL-----KATEEKLLDLDALRKASSEGK 776
Query: 405 RDMGLFLSLIE--KRLVELLTVQAFLHAQSFTSLA------DAALLVLGQSLEDLPKKMA 456
+M +E ++ ++ L ++ + +S+ + L L ++L ++ +
Sbjct: 777 SEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKE 836
Query: 457 PLQPPDTLEDPPGFEASDDYPMSREELLSQVEKLVELQEQ 496
L+ + EAS++ + + V KL + +EQ
Sbjct: 837 TLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQ 876
Score = 32.7 bits (73), Expect = 1.1
Identities = 37/233 (15%), Positives = 89/233 (38%), Gaps = 12/233 (5%)
Query: 9 SKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQVQA 68
+K+ + ++ +L+ ++ ++ ++ S V+ + + + ++ L + AQ
Sbjct: 1101 TKQTNAKLQNELDTLKE-NNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQ 1159
Query: 69 EIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLDRVTCH 128
++ LQE+ L +++ + +H K + +Q +++++R D
Sbjct: 1160 QLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKAS 1219
Query: 129 FDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSAYAV---- 184
+ +AL E D + V R LH +V TL
Sbjct: 1220 LQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNL 1279
Query: 185 -------REEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLK 230
+ + + G +A+++E E + L I+ L++ + LK+K
Sbjct: 1280 ELQLKENKRQLSSSSGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLKMK 1332
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 65.5 bits (158), Expect = 2e-10
Identities = 74/382 (19%), Positives = 169/382 (44%), Gaps = 24/382 (6%)
Query: 4 ERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGR 63
E+ + + +R K EE + E +Q Q Q ++ QRL L +
Sbjct: 444 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 503
Query: 64 AQVQAEIEELQEQTRALDKQIQEW--ETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQ 121
++Q + E++ EQ + Q + W E +++ K + +Q+ K+R + + + +Q
Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 563
Query: 122 LDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSA 181
+R+ Q + E++ + R ++K+++E + +
Sbjct: 564 EERMEKKTQEQEKKTWDQEEKMR----EEERMREREKKMREEEEMMREQEEKMQEQEEKM 619
Query: 182 YAVREEAKAKMGLLRERAEK----EEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPD 237
E+ + ++E+ EK EE E E ++ ++Q L ++ KL +++ +
Sbjct: 620 QEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQK----EKLWEHEKMQE 675
Query: 238 PDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEERN 297
+ ++++E++ E E + K +QE+ ++ + + M E + +K E EE
Sbjct: 676 QEKMQEQEEKIWE-QEKMEKKTQEQEKKTWDQEKMREEESMRERE-----KKMREEEEMM 729
Query: 298 FAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQ----QRMDKV 353
+ + EQ +++ +EE+ E +E + +Q L EQ++K+ + Q +K+
Sbjct: 730 REQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKI 789
Query: 354 HSEAERLEARFQDVRGQLEKLK 375
+ E++ + + +RGQ EK++
Sbjct: 790 WEQEEKMRDQEEKMRGQEEKMR 811
Score = 48.9 bits (115), Expect = 2e-05
Identities = 54/385 (14%), Positives = 166/385 (43%), Gaps = 32/385 (8%)
Query: 10 KEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQVQAE 69
+E ++I +Q E+IR EE+ G + K R + E D++ + +++ +
Sbjct: 507 QEQEEKIWEQEEKIRDQEEMWGQ----------EKKMWRQEKMREQEDQMWEQEEKMRDQ 556
Query: 70 IEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLDRVTCHF 129
+++ +Q ++K+ QE E + + + +R + +++ K+R ++ Q +++
Sbjct: 557 EQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE 616
Query: 130 DNQLVRNAALREELDLLRIDRNRYLNVDRKL---------------KKEIHHLHHLVSTL 174
+ + + E+ + ++ + + K+ +KE H +
Sbjct: 617 EKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQ 676
Query: 175 ILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDR 234
+ E+ K + + + + + E + ++ + + + ++ +
Sbjct: 677 EKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKM 736
Query: 235 QPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIE 294
Q + ++++E++ E E +W+ ++ + + L + + + E + +K E E
Sbjct: 737 QEQEEKMQEQEEEMWEQEEKMWEQEEK---MWEQQRLPEQKEKLWEHEKMQEQEKIWEQE 793
Query: 295 ERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARAS---KDDQHLLQEQQQKVLQQRMD 351
E+ + + Q ++ +E+++ +E + ++++ QE++ +++M+
Sbjct: 794 EKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKME 853
Query: 352 -KVHSEAERLEARFQDVRGQLEKLK 375
K+ + E++ + + +RGQ EK++
Sbjct: 854 EKMQGQEEKMREQEEKMRGQEEKMR 878
Score = 48.1 bits (113), Expect = 3e-05
Identities = 66/358 (18%), Positives = 148/358 (41%), Gaps = 36/358 (10%)
Query: 13 HQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQVQAEIEE 72
H++ ++ +EE+ + + L++ + N+ + ++++ E + ++++Q ++E
Sbjct: 192 HKKADRYIEELTKERDALS-LELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKE 250
Query: 73 L------------QEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILEN 120
L Q QT L +++ E + K +R Q+ K+ R+ L
Sbjct: 251 LKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRK------QEEKMWRQEERLRE 304
Query: 121 QLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTS 180
Q ++ + + LRE+ LR ++ + L ++L+++ + +
Sbjct: 305 QEGKMREQEEKMWRQEKRLREQEKELR-EQEKELREQKELREQEEQMQEQEEKMWEQEEK 363
Query: 181 AYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPDV 240
E + KM ER ++E Q + Q ++ Q + + L+ K
Sbjct: 364 M----REQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK---------- 409
Query: 241 LEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEERNFAE 300
E+R ++ ++ E V K +E+ + E + M E + +K + EE E
Sbjct: 410 -EERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMRE 468
Query: 301 FNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAE 358
++ E QEE + Q+ L + +Q +QEQ++K+ +Q +K+ + E
Sbjct: 469 QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE-EKIRDQEE 525
Score = 46.2 bits (108), Expect = 1e-04
Identities = 50/232 (21%), Positives = 107/232 (46%), Gaps = 17/232 (7%)
Query: 156 VDRKLKKEIHHLHHLVSTLILSSTSAYA---VREEAKAKMGLLRER---AEKEEAQSEME 209
V + KK ++ L S Y EE K K L+E+ AE E+++ ++
Sbjct: 188 VSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLN 247
Query: 210 AQVLQRQILHLEQLHHFL-KLKNNDRQPD----PDVLEKREKQAGEVAEGVWKTSQERLV 264
+ L+R+ LE+ L +++ N Q + + L ++EK+ + E +W+ QE +
Sbjct: 248 VKELKRK---LERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWR--QEERL 302
Query: 265 LCYEDALNKLSQLMGESDPDLLVQ-KYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQE 323
E + + + M + L Q K L +E+ E + EQ +++ +E++ E +E
Sbjct: 303 REQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEE 362
Query: 324 ALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEKLK 375
+ Q +Q+K ++++ K+ + ER+ + + +R + E+++
Sbjct: 363 KMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR 414
>gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]
Length = 775
Score = 63.5 bits (153), Expect = 6e-10
Identities = 93/416 (22%), Positives = 167/416 (40%), Gaps = 86/416 (20%)
Query: 1 MEGERRAYSKEV-----------HQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRD 49
+EGE + +++ H R +Q + L E++ LQ + + +R
Sbjct: 211 LEGELKGLQEQIAETKARLITQQHDRAQEQSDHALMLRELQKLLQ------EERTQRQDL 264
Query: 50 SQRLENMDRLLKGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKV 109
RLE L GRA ++E + QT+ L ++++E ++ + I D+K
Sbjct: 265 ELRLEETREALAGRAYAAEQMEGFELQTKQLTREVEELKSELQA----------IRDEKN 314
Query: 110 KIRRRIRILENQLDRVTCHFDNQL---VRNAALREELDLLRIDRNRYLNVDRKLKKEIHH 166
+ R++ L+ + R+ HF QL +R AL E D LR L+ +I
Sbjct: 315 QPDPRLQELQEEAARLKSHFQAQLQQEMRKTALAE--DQLRQQSQVEEQRVAALENQISE 372
Query: 167 LHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHF 226
+ L+ T EK + + ++ Q L+ +IL L+ +
Sbjct: 373 VSELLGTY-------------------------EKAKQKDQLAIQKLKERILQLDLENKT 407
Query: 227 LKLKNNDRQP----------DPDVLEKREKQAGEVAEGVWKTSQERL---VLCYEDALNK 273
L L + R P D +VL+ + ++ + + + SQ L LC + +
Sbjct: 408 LALAASSRSPLDSHGEESSLDVNVLKDKMEKLKRLLQVAARKSQVTLDVEKLCDLEIMPS 467
Query: 274 LSQLMGESDPDLLVQKYLEIEERNFAEFNF----------INEQNL--ELEHVQEEIKEM 321
GE L Q+ L+ + F + + NL ELE QE++ E+
Sbjct: 468 SEAADGEKATALYYQQELKQLKEEFERYKMRAQVVLKSKNTKDGNLGKELEAAQEQLAEL 527
Query: 322 QEALVSARASKDD---QHLLQEQQQKVLQQRMDKVH-SEAERLEARFQDVRGQLEK 373
+E +S R S ++ QH + K R+ ++H E ER + F+D +LE+
Sbjct: 528 KEKYISLRLSCEELEHQHQQEADDWKQELARLQQLHRQELERCQLDFRDRTLKLEE 583
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 62.4 bits (150), Expect = 1e-09
Identities = 72/373 (19%), Positives = 161/373 (43%), Gaps = 56/373 (15%)
Query: 4 ERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGR 63
E+ + + +R K EE + E +Q Q Q ++ QRL L +
Sbjct: 386 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 445
Query: 64 AQVQAEIEELQEQTRALDKQIQEW--ETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQ 121
++Q + E++ EQ + Q + W E +++ K + +Q+ K+R + + + +Q
Sbjct: 446 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 505
Query: 122 LDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSA 181
+R+ ++ LRE+ + +R ++ + + K+++E
Sbjct: 506 EERMW-------EQDERLREKEERMR-EQKKMWQQEEKMREE------------------ 539
Query: 182 YAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPDVL 241
+E + K E+ +EE E E ++ + + + EQ + + R+ + +
Sbjct: 540 -KKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMW 598
Query: 242 EKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEERNFAEF 301
E+ EK E E +W+ ++ ED + + ++M E + +K E EE+ +
Sbjct: 599 EQEEKMQ-EQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQE-----EKMQEQEEKMW--- 649
Query: 302 NFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLE 361
EQ ++ +E+++E +E + Q Q++K+ +Q +K+ + E++
Sbjct: 650 ----EQEEKMREQEEKMREQEEKM-------------QGQEEKMREQE-EKMQGQEEKMR 691
Query: 362 ARFQDVRGQLEKL 374
+ + +RGQ EK+
Sbjct: 692 EQEEKMRGQEEKM 704
Score = 47.0 bits (110), Expect = 6e-05
Identities = 62/302 (20%), Positives = 127/302 (42%), Gaps = 45/302 (14%)
Query: 111 IRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHL 170
+RR I ++ + +TC + AL D R + L + L +HH H
Sbjct: 83 LRREIEAQDHTIRILTCQ---KTELETALYYSQDAARKFEDGNLGESKDLAGRLHHSWHF 139
Query: 171 VSTL--ILSSTSAY--------------------------AVREEAKAKMGLLRER---A 199
L LS+ S + EE K K L+E+ A
Sbjct: 140 AGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLA 199
Query: 200 EKEEAQSEMEAQVLQRQILHLEQLHHFL-KLKNNDRQPD----PDVLEKREKQAGEVAEG 254
E E+++ ++ + L+R+ LE+ L +++ N Q + + L ++EK+ + E
Sbjct: 200 ESEKSEIQLNVKELKRK---LERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEK 256
Query: 255 VWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQ-KYLEIEERNFAEFNFINEQNLELEH 313
+W+ QE + E + + + M + L Q K L +E+ E + EQ +++
Sbjct: 257 MWR--QEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQE 314
Query: 314 VQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEK 373
+E++ E +E + Q +Q+K ++++ K+ + ER+ + + +R + E+
Sbjct: 315 QEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEER 374
Query: 374 LK 375
++
Sbjct: 375 MR 376
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 62.0 bits (149), Expect = 2e-09
Identities = 106/531 (19%), Positives = 227/531 (42%), Gaps = 85/531 (16%)
Query: 10 KEVHQRINKQLEEIR-RLEEVRGDLQVQISA-------AQNQVKRLRDSQRLENMDRLLK 61
+ + Q ++LE++R L+E+ G VQ+ AQ + + R +EN R
Sbjct: 420 QRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYS 479
Query: 62 GRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQ 121
+ +I+ + L+ ++Q+ ++ K G IL++K ++R++ L +
Sbjct: 480 NITVNEDQIKLMNVAINELNIKLQDTNSQ---KEKLKEELGLILEEKCALQRQLEDLVEE 536
Query: 122 LDRVTCHFDNQLVRNA--ALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLIL--- 176
L F + ++ A + E+ L + ++ L+ LK EI L L
Sbjct: 537 LS-----FSREQIQRARQTIAEQESKLN-EAHKSLSTVEDLKAEIVSASESRKELELKHE 590
Query: 177 SSTSAYAVREEA--KAKMGLLRERAEKEEAQSEMEAQVLQRQIL--HLEQLHHFLKLKNN 232
+ + Y ++ E K K +L AE +EA+ E L+ Q+L H E+L KLK +
Sbjct: 591 AEVTNYKIKLEMLEKEKNAVLDRMAESQEAELER----LRTQLLFSHEEELS---KLKED 643
Query: 233 DRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLE 292
+EK + G + Y+ ++ L M + +
Sbjct: 644 LEIEHRINIEKLKDNLG---------------IHYKQQIDGLQNEMSQ-----------K 677
Query: 293 IEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARAS----------KDDQHLLQEQQ 342
IE F + N I +QN + + + +K++Q++LV++++ K+ + L QE++
Sbjct: 678 IETMQFEKDNLITKQNQLILEISK-LKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEK 736
Query: 343 QK-VLQQRMDKVHSEAERLEARFQDVRGQLEKLKADIQLLFTKAHCDSSMIDDLLGVKTS 401
+K L+Q + ++ + E LE + ++ L++ A ++ + + ++D+L + T
Sbjct: 737 EKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTP 796
Query: 402 MGDRDMGLFLSLIEKRLVELLTVQAFLHAQSFTSLADAALLVLGQSLEDLPKKMAPLQPP 461
+ + +FL I+ ++S S+ + + +L + EDL ++ L
Sbjct: 797 VSQEERLIFLDSIK--------------SKSKDSVWEKEIEILIEENEDLKQQCIQLNEE 842
Query: 462 DTLEDPPGFEASDDYPMSREELLSQVEKLVELQEQAEAQRQKDLAAAAAKL 512
+ A ++ ++ +EL + L+++++ E + K +KL
Sbjct: 843 IEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKL 893
Score = 52.8 bits (125), Expect = 1e-06
Identities = 87/458 (18%), Positives = 207/458 (45%), Gaps = 65/458 (14%)
Query: 15 RINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQVQAEIE--- 71
R+ + E ++++E R L Q A + + + + Q L+ ++L+K + +VQ + E
Sbjct: 1958 RLQELEAEQQQIQEERELLSRQKEAMKAEAGPV-EQQLLQETEKLMKEKLEVQCQAEKVR 2016
Query: 72 -ELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLDRVTCHFD 130
+LQ+Q +AL+ ++E +R + + + + +R++ + LE QL+++ D
Sbjct: 2017 DDLQKQVKALEIDVEEQVSRFIELEQEKNT------ELMDLRQQNQALEKQLEKMRKFLD 2070
Query: 131 NQLVRNAALRE--ELDLLRIDRN-----RYLNVDRKLKKEIHHL-HHL------VSTLIL 176
Q + R+ + ++ ++++ R+ + +E+ L +HL S L+L
Sbjct: 2071 EQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLL 2130
Query: 177 SSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDR-- 234
S +E ++ L R + E + A Q+ +E HF ++
Sbjct: 2131 SKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQK----VEDRKHFGAVEAKPELS 2186
Query: 235 -----QPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQK 289
Q + D ++++EK+ + +E+L E+ NK ++ Q
Sbjct: 2187 LEVQLQAERDAIDRKEKEITNL--------EEQLEQFREELENKNEEVQ---------QL 2229
Query: 290 YLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARA-SKDDQHLLQEQQQKVLQQ 348
++++E + + E E + +++++++ A+ + A S DQH+L + +++Q+
Sbjct: 2230 HMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQE 2289
Query: 349 R---MDKVHSEAERLEARFQDVRGQ--LEKLKADIQLLFTKAHCDSSMIDDLLGVKTSMG 403
+ +D+++ + +L+ + + +E+ I+ L T+ C ++ D VK +
Sbjct: 2290 KEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIEC---LMSDQECVKRNR- 2345
Query: 404 DRDMGLFLSLIEKRLVELLTV--QAFLHAQSFTSLADA 439
+ ++ +IEK EL + + ++A S + AD+
Sbjct: 2346 EEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADS 2383
Score = 51.6 bits (122), Expect = 2e-06
Identities = 73/379 (19%), Positives = 164/379 (43%), Gaps = 47/379 (12%)
Query: 2 EGERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLK 61
E ER + +E+ Q++ +QL+ + R + + ++ N +K ++ + LL
Sbjct: 2077 EHERDVFQQEI-QKLEQQLKVVPRFQPISEHQTREVEQLANHLK-----EKTDKCSELLL 2130
Query: 62 GRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQ 121
+ Q+Q +I+E E+ L+ +++E E + + QKV+ R+ +E +
Sbjct: 2131 SKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTF--------QKVEDRKHFGAVEAK 2182
Query: 122 LDRVTCHFDNQLVRNAALREELDLLRIDR--NRYLNVDRKLKKEIHHLHHLVSTLILSST 179
++ Q R+A R+E ++ ++ ++ +E+ LH + ST
Sbjct: 2183 -PELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKEST 2241
Query: 180 SAYAVREEAKAKMGLLRERAEK-EEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDP 238
+ +E + + L ++ EK A E +A Q Q H L K
Sbjct: 2242 TRL---QELEQENKLFKDDMEKLGLAIKESDAMSTQDQ--------HVLFGK------FA 2284
Query: 239 DVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDL-LVQKYLEIEERN 297
+++++E + ++ E V K Q+ + + + ++L+ + + + + E +RN
Sbjct: 2285 QIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRN 2344
Query: 298 FAEFNFINEQNLELEHVQEEIKEMQEALVS-ARASKDDQHLLQEQQQKVLQQRMDKVHSE 356
E E+E + E I+++Q+ L + + + + H L E+ L+ ++D V +E
Sbjct: 2345 REE---------EIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADS-LKHQLDVVIAE 2394
Query: 357 AERLEARFQDVRGQLEKLK 375
LE + + ++ +K
Sbjct: 2395 KLALEQQVETANEEMTFMK 2413
Score = 51.6 bits (122), Expect = 2e-06
Identities = 100/459 (21%), Positives = 194/459 (42%), Gaps = 65/459 (14%)
Query: 1 MEGERRAYSKEVHQRIN--KQLEEIRR--------LEEVRGDLQVQISAAQNQVKRLRDS 50
++ ER A ++ + N +QLE+ R ++++ L++Q + +++ L
Sbjct: 2191 LQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQE 2250
Query: 51 QRLENMDRLLKGRAQVQAEIEELQEQTRALDKQ---IQEWETRIFTHSKNVRSPGFILDQ 107
+L D G A +++ Q+Q K IQE E I ++ V L Q
Sbjct: 2251 NKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTK----LQQ 2306
Query: 108 KVKIRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHL 167
++KI +++E + N+L+R+ L +++ L D+ V R ++EI L
Sbjct: 2307 QLKITTDNKVIEEK---------NELIRD--LETQIECLMSDQEC---VKRNREEEIEQL 2352
Query: 168 HHLVSTLIL--------SSTSAYAVREEAK----------AKMGLLRERAEKEEAQSEME 209
+ ++ L +S +A+++ EEA A+ L ++ E +
Sbjct: 2353 NEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFM 2412
Query: 210 AQVLQRQILHLEQLHHFLKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYED 269
VL+ + QL L +R+ + E + + K E V+ ED
Sbjct: 2413 KNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTED 2472
Query: 270 ALNKL-SQLMGESDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQE--ALV 326
AL L +Q +S + + +E R + ++ ++LEL ++IK+MQE
Sbjct: 2473 ALKSLENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFE 2532
Query: 327 SARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLEARF-QDVRG-QLEKLKADIQLLFTK 384
+ K +L + ++KV + ++ EA + A+F QD + E + +IQ L
Sbjct: 2533 TEMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNL--- 2589
Query: 385 AHCDSSMIDDLLGVKTSMGDRDMGLFLSLIEKRLVELLT 423
+ + +D LG S + L +S +E ++VE+ T
Sbjct: 2590 ----NQLREDELGSDISA----LTLRISELESQVVEMHT 2620
Score = 49.3 bits (116), Expect = 1e-05
Identities = 118/626 (18%), Positives = 248/626 (39%), Gaps = 114/626 (18%)
Query: 1 MEGERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLL 60
ME E E+ + +N++LEE+R G Q+Q A + + +Q N+ +
Sbjct: 160 MESELAGKQHEIEE-LNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQAR 218
Query: 61 KGRAQVQAEIEELQEQTRALDKQIQEWET---------------------RIFTHSKNVR 99
+ + + E EL EQ++ L Q Q+ + +I TH + +
Sbjct: 219 REKDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLE 278
Query: 100 SPGFILD--QKVK---------IRRRIRILENQLDRVTCHFDNQLVRNA-ALREELDLLR 147
+L+ QK K ++ +I++ E + D+ + + + ++ + EEL+
Sbjct: 279 EQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKI 338
Query: 148 ID--------RNRYLNVDR---KLKKEIHHLHHLVSTLILSSTSAYAVR----EEAKAKM 192
I+ +++ D+ +L+++I + + + L T++ EE K M
Sbjct: 339 IEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLM 398
Query: 193 GLLRERAEKEEAQSEMEAQVLQRQILH----LEQL---------HHFLKLKNN-DRQPDP 238
G + E ++ S+ E ++QR LEQL +++K RQ
Sbjct: 399 GTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMA 458
Query: 239 DVLEKREKQAGEVAEGVWK----TSQERLVLCYEDALNKLSQLMGES------------- 281
+ E + + GE+ + T E + A+N+L+ + ++
Sbjct: 459 QMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGL 518
Query: 282 --DPDLLVQKYLE--IEERNFAEFNF------INEQNLELEHVQEE---IKEMQEALVSA 328
+ +Q+ LE +EE +F+ I EQ +L + +++++ +VSA
Sbjct: 519 ILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSA 578
Query: 329 RASKDDQHL---------------LQEQQQKVLQQRMDKVHSEAERLEARFQ-DVRGQLE 372
S+ + L L++++ VL + + +E ERL + +L
Sbjct: 579 SESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELS 638
Query: 373 KLKADIQLLFTKAHCDSSMIDDLLGVKTSMGDRDMGLFLSLIEKRLVELLTVQAFLHAQS 432
KLK D+++ + + + D LG+ + GL + +K + Q+
Sbjct: 639 KLKEDLEI---EHRINIEKLKDNLGIHYK--QQIDGLQNEMSQKIETMQFEKDNLITKQN 693
Query: 433 FTSLADAALLVLGQSLEDLPKKMAPLQPPDTLEDPPGFEASDDYPMSREELLSQVEKLVE 492
L + L L QSL + + LQ + ++ + + E+ + +++ E
Sbjct: 694 QLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTE 753
Query: 493 LQEQAEAQRQKDLAAAAAKLDGTLSV 518
L E+ +++ DL A+L+ S+
Sbjct: 754 LLEKQMKEKENDLQEKFAQLEAENSI 779
Score = 45.1 bits (105), Expect = 2e-04
Identities = 85/420 (20%), Positives = 175/420 (41%), Gaps = 44/420 (10%)
Query: 9 SKEVHQRIN---KQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQ 65
S+E+ +IN K++E +R+ E+ +G L+ ++ Q + + L + Q E + L + AQ
Sbjct: 714 SEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELL-EKQMKEKENDLQEKFAQ 772
Query: 66 VQAEIEELQEQTRALDKQIQ------EWETRIFTHSKNVRSPGFILDQKVKI-------- 111
++AE L+++ + L+ ++ + E IF S +S + +++++I
Sbjct: 773 LEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDL 832
Query: 112 -RRRIRI---LENQLDRVTCHFDNQLVRNAALREEL--------DLLRIDRNRYLNVDRK 159
++ I++ +E Q + + N V L+EE DL + L K
Sbjct: 833 KQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSK 892
Query: 160 LK--KEIHHLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQI 217
LK E HL + T + +S + + A+ + E EK+ + + +V +R+
Sbjct: 893 LKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREK 952
Query: 218 LHLEQLHHFLKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQL 277
L L Q L + + + L + K + E V +E ++ + +
Sbjct: 953 LELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINHNRAENVQSC 1012
Query: 278 MGESDPDLLVQKYLEIEERNF-AEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQH 336
++ L+ + + R + +N+ E + E K E + SK +Q
Sbjct: 1013 --DTQVSSLLDGVVTMTSRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQL 1070
Query: 337 LL-------QEQQQKVLQ-QRMDKVHSEAERLEARFQDVRGQLEKLKADIQLLFTKAHCD 388
+L +E + Q DK+ E L++ D+R Q+E + + L+++ H D
Sbjct: 1071 ILDHLPSVTKESSLRATQPSENDKLQKELNVLKSEQNDLRLQMEAQRICLSLVYS-THVD 1129
Score = 39.3 bits (90), Expect = 0.012
Identities = 77/414 (18%), Positives = 170/414 (41%), Gaps = 31/414 (7%)
Query: 104 ILDQKVKIRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKE 163
+L+ +++ + L + + ++ V L E + + L +L++
Sbjct: 1843 MLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRER 1902
Query: 164 IHHLHHLVSTLILSSTSAYAVREE-AKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQ 222
+H L + + A V + A K R+ EK + +E ++L L++
Sbjct: 1903 LHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASN-RLQE 1961
Query: 223 LHHFLKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERL-----VLCY----EDALNK 273
L + +R+ E + +AG V + + + +++ + V C D L K
Sbjct: 1962 LEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQK 2021
Query: 274 LSQLMGESDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKD 333
+ + E D + V +++E+E+ E+N EL ++++ + +++ L R D
Sbjct: 2022 QVKAL-EIDVEEQVSRFIELEQ----------EKNTELMDLRQQNQALEKQLEKMRKFLD 2070
Query: 334 DQHLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEKLKADIQLLFTKAHCDSSMID 393
+Q + +E ++ V QQ + K+ + ++ RFQ + E +++ L +
Sbjct: 2071 EQAIDREHERDVFQQEIQKLEQQL-KVVPRFQPIS---EHQTREVEQLANHLKEKTDKCS 2126
Query: 394 DLLGVKTSMGDRDMGLFLSLIEKR--LVELLTVQAFLHAQSFTSLADAALLVLGQSLEDL 451
+LL K + RD+ IEK V L + A +F + D ++ +L
Sbjct: 2127 ELLLSKEQL-QRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPEL 2185
Query: 452 PKKMAPLQPPDTLE--DPPGFEASDDYPMSREELLSQVEKLVELQEQAEAQRQK 503
++ D ++ + + REEL ++ E++ +L Q E Q+++
Sbjct: 2186 SLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKE 2239
Score = 38.9 bits (89), Expect = 0.016
Identities = 71/377 (18%), Positives = 157/377 (41%), Gaps = 52/377 (13%)
Query: 26 LEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQVQAEIEELQEQTRALDKQIQ 85
L E++ L Q++ + +KR ++S++ + + L Q Q+++ E+Q + ++ +
Sbjct: 3091 LSEIQA-LHAQMNGRKITLKREQESEK-PSQELLEYNIQQKQSQMLEMQVELSSMKDRAT 3148
Query: 86 EWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLDRVTCHFDNQLVRNAALREELDL 145
E + ++ + V L+++L + + L +EL+
Sbjct: 3149 ELQEQLSSEKMVVAE-----------------LKSELAQTKLELETTLKAQHKHLKELEA 3191
Query: 146 LRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQ 205
R++ + E+H L+ +++ S E+ KAK+G ER ++E
Sbjct: 3192 FRLEV-------KDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELED 3244
Query: 206 SEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPDV------LEKREKQAGEVAEGVWKTS 259
+ + +++ L L L K N+ Q + + E+Q + V S
Sbjct: 3245 LKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLES 3304
Query: 260 QERLVLCYEDALNKLSQL---------MGESDP-----DLLVQKYLEIEERNFAEFNFIN 305
++ + L++ +L G+S P DLL + ++EE++ +N
Sbjct: 3305 EKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLN 3364
Query: 306 E-QNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLEARF 364
E + +L+ +Q + ++ V + + +Q E Q+K M ++ S+ E L+ +
Sbjct: 3365 ETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKK-----MHELQSKVEDLQRQL 3419
Query: 365 QDVRGQLEKLKADIQLL 381
++ R Q+ KL + Q L
Sbjct: 3420 EEKRQQVYKLDLEGQRL 3436
Score = 38.1 bits (87), Expect = 0.027
Identities = 45/217 (20%), Positives = 101/217 (46%), Gaps = 18/217 (8%)
Query: 191 KMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPDVLEKREKQAGE 250
K+ L RE+ ++ +Q +E + Q+Q LE +K+ + + E+ +
Sbjct: 3105 KITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATE----LQEQLSSEKMV 3160
Query: 251 VAEGVWKTSQERLVL-----CYEDALNKLS----QLMGESDPDLLVQKYLEIEERNFAEF 301
VAE + +Q +L L L +L ++ ++D L+ L E++ E
Sbjct: 3161 VAELKSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSREL 3220
Query: 302 NF-INEQNLEL----EHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSE 356
+ + ++ +L E +EE+++++ +L S + +LL EQQ+++L + K+ S+
Sbjct: 3221 QWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQ 3280
Query: 357 AERLEARFQDVRGQLEKLKADIQLLFTKAHCDSSMID 393
+A+ + +G+ +L+ ++ + SS +D
Sbjct: 3281 RMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLD 3317
Score = 34.7 bits (78), Expect = 0.29
Identities = 88/426 (20%), Positives = 176/426 (41%), Gaps = 70/426 (16%)
Query: 45 KRLRDSQRLENMDRLLKGRAQVQAEIEELQEQTRALDKQIQEWETR------IFTHSK-- 96
++L SQRL ++ LK Q EI L E+ ++L ++ ++ R I H++
Sbjct: 951 EKLELSQRLSDLSEQLK---QKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINHNRAE 1007
Query: 97 NVRS----PGFILDQKVKIRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNR 152
NV+S +LD V + R E + +V N + EE ++ D+
Sbjct: 1008 NVQSCDTQVSSLLDGVVTMTSRGA--EGSVSKV----------NKSFGEESKIMVEDKVS 1055
Query: 153 YLN--VDRKLKKEIHHLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEA 210
+ N V + K+E L HL S SS A E K + L ++E+ + + +MEA
Sbjct: 1056 FENMTVGEESKQEQLILDHLPSVTKESSLRATQPSENDKLQKELNVLKSEQNDLRLQMEA 1115
Query: 211 QVLQRQIL---HLEQLHHFL---------------------KLKNNDRQPDPDVLEKREK 246
Q + ++ H++Q+ ++ K+K + ++ + +
Sbjct: 1116 QRICLSLVYSTHVDQVREYMENEKDKALCSLKEELIFAQEEKIKELQKIHQLELQTMKTQ 1175
Query: 247 QAGEVAEGVWKTSQERLVLCYEDA---LNKLSQLMGESDPDLLVQKYLEIEERNFAEFNF 303
+ G+ + + + E+ L L ++GE L + ++ N ++
Sbjct: 1176 ETGDEGKPLHLLIGKLQKAVSEECSYFLQTLCSVLGEYYTPALKCEVNAEDKENSGDYIS 1235
Query: 304 INEQNLELEHVQEEIKEMQEALVSARASKDDQH----LLQEQQQKVLQQRMD--KVHSEA 357
NE + EL+ + E+++ QE + + +++ +LQ + K+ Q+ D K+
Sbjct: 1236 ENE-DPELQDYRYEVQDFQENMHTLLNKVTEEYNKLLVLQTRLSKIWGQQTDGMKLEFGE 1294
Query: 358 ERL---EARFQDVRGQLEKLKADIQLLFTKAHCDSSMIDDLLGVKTSMGDRDMGLFLSLI 414
E L E F + Q+ L+ DI + S + DL K +++ +S +
Sbjct: 1295 ENLPKEETEFLSIHSQMTNLE-DIDV---NHKSKLSSLQDLEKTKLEEQVQELESLISSL 1350
Query: 415 EKRLVE 420
+++L E
Sbjct: 1351 QQQLKE 1356
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 62.0 bits (149), Expect = 2e-09
Identities = 106/531 (19%), Positives = 227/531 (42%), Gaps = 85/531 (16%)
Query: 10 KEVHQRINKQLEEIR-RLEEVRGDLQVQISA-------AQNQVKRLRDSQRLENMDRLLK 61
+ + Q ++LE++R L+E+ G VQ+ AQ + + R +EN R
Sbjct: 420 QRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYS 479
Query: 62 GRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQ 121
+ +I+ + L+ ++Q+ ++ K G IL++K ++R++ L +
Sbjct: 480 NITVNEDQIKLMNVAINELNIKLQDTNSQ---KEKLKEELGLILEEKCALQRQLEDLVEE 536
Query: 122 LDRVTCHFDNQLVRNA--ALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLIL--- 176
L F + ++ A + E+ L + ++ L+ LK EI L L
Sbjct: 537 LS-----FSREQIQRARQTIAEQESKLN-EAHKSLSTVEDLKAEIVSASESRKELELKHE 590
Query: 177 SSTSAYAVREEA--KAKMGLLRERAEKEEAQSEMEAQVLQRQIL--HLEQLHHFLKLKNN 232
+ + Y ++ E K K +L AE +EA+ E L+ Q+L H E+L KLK +
Sbjct: 591 AEVTNYKIKLEMLEKEKNAVLDRMAESQEAELER----LRTQLLFSHEEELS---KLKED 643
Query: 233 DRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLE 292
+EK + G + Y+ ++ L M + +
Sbjct: 644 LEIEHRINIEKLKDNLG---------------IHYKQQIDGLQNEMSQ-----------K 677
Query: 293 IEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARAS----------KDDQHLLQEQQ 342
IE F + N I +QN + + + +K++Q++LV++++ K+ + L QE++
Sbjct: 678 IETMQFEKDNLITKQNQLILEISK-LKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEK 736
Query: 343 QK-VLQQRMDKVHSEAERLEARFQDVRGQLEKLKADIQLLFTKAHCDSSMIDDLLGVKTS 401
+K L+Q + ++ + E LE + ++ L++ A ++ + + ++D+L + T
Sbjct: 737 EKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTP 796
Query: 402 MGDRDMGLFLSLIEKRLVELLTVQAFLHAQSFTSLADAALLVLGQSLEDLPKKMAPLQPP 461
+ + +FL I+ ++S S+ + + +L + EDL ++ L
Sbjct: 797 VSQEERLIFLDSIK--------------SKSKDSVWEKEIEILIEENEDLKQQCIQLNEE 842
Query: 462 DTLEDPPGFEASDDYPMSREELLSQVEKLVELQEQAEAQRQKDLAAAAAKL 512
+ A ++ ++ +EL + L+++++ E + K +KL
Sbjct: 843 IEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKL 893
Score = 55.8 bits (133), Expect = 1e-07
Identities = 91/445 (20%), Positives = 192/445 (43%), Gaps = 69/445 (15%)
Query: 15 RINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQVQAEIE--- 71
R+ + E ++++E R L Q A + + + + Q L+ ++L+K + +VQ + E
Sbjct: 1958 RLQELEAEQQQIQEERELLSRQKEAMKAEAGPV-EQQLLQETEKLMKEKLEVQCQAEKVR 2016
Query: 72 -ELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLDRVTCHFD 130
+LQ+Q +AL+ ++E +R + + + + +R++ + LE QL+++ D
Sbjct: 2017 DDLQKQVKALEIDVEEQVSRFIELEQEKNT------ELMDLRQQNQALEKQLEKMRKFLD 2070
Query: 131 NQLVRNAALRE--ELDLLRIDRN-----RYLNVDRKLKKEIHHL-HHL------VSTLIL 176
Q + R+ + ++ ++++ R+ + +E+ L +HL S L+L
Sbjct: 2071 EQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLL 2130
Query: 177 SSTS---------------AYAVREEAKAKMGLLRERAEKEEAQSEMEAQV--------- 212
S + VRE +A + R+ EA+ E+ +V
Sbjct: 2131 SKEQLQRDIQERNEEIEKLEFRVRELEQALLVEDRKHFGAVEAKPELSLEVQLQAERDAI 2190
Query: 213 --LQRQILHL-EQLHHF---LKLKNNDRQPDPDVLEKREKQAG------EVAEGVWKTSQ 260
+++I +L EQL F L+ KN + Q LE ++K++ E ++K
Sbjct: 2191 DRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDM 2250
Query: 261 ERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEERNFAEFNFINEQNLELEH---VQEE 317
E+L L ++ S M D +L K+ +I + E + +NEQ +L+ + +
Sbjct: 2251 EKLGLAIKE-----SDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTD 2305
Query: 318 IKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEKLKAD 377
K ++E R + L Q+ V + R +++ E +E Q++ +K +
Sbjct: 2306 NKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTSMN 2365
Query: 378 IQLLFTKAHCDSSMIDDLLGVKTSM 402
L +A +D ++ K ++
Sbjct: 2366 AHSLSEEADSLKHQLDVVIAEKLAL 2390
Score = 51.6 bits (122), Expect = 2e-06
Identities = 100/459 (21%), Positives = 194/459 (42%), Gaps = 65/459 (14%)
Query: 1 MEGERRAYSKEVHQRIN--KQLEEIRR--------LEEVRGDLQVQISAAQNQVKRLRDS 50
++ ER A ++ + N +QLE+ R ++++ L++Q + +++ L
Sbjct: 2183 LQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQE 2242
Query: 51 QRLENMDRLLKGRAQVQAEIEELQEQTRALDKQ---IQEWETRIFTHSKNVRSPGFILDQ 107
+L D G A +++ Q+Q K IQE E I ++ V L Q
Sbjct: 2243 NKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTK----LQQ 2298
Query: 108 KVKIRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHL 167
++KI +++E + N+L+R+ L +++ L D+ V R ++EI L
Sbjct: 2299 QLKITTDNKVIEEK---------NELIRD--LETQIECLMSDQEC---VKRNREEEIEQL 2344
Query: 168 HHLVSTLIL--------SSTSAYAVREEAK----------AKMGLLRERAEKEEAQSEME 209
+ ++ L +S +A+++ EEA A+ L ++ E +
Sbjct: 2345 NEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFM 2404
Query: 210 AQVLQRQILHLEQLHHFLKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYED 269
VL+ + QL L +R+ + E + + K E V+ ED
Sbjct: 2405 KNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTED 2464
Query: 270 ALNKL-SQLMGESDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQE--ALV 326
AL L +Q +S + + +E R + ++ ++LEL ++IK+MQE
Sbjct: 2465 ALKSLENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFE 2524
Query: 327 SARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLEARF-QDVRG-QLEKLKADIQLLFTK 384
+ K +L + ++KV + ++ EA + A+F QD + E + +IQ L
Sbjct: 2525 TEMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNL--- 2581
Query: 385 AHCDSSMIDDLLGVKTSMGDRDMGLFLSLIEKRLVELLT 423
+ + +D LG S + L +S +E ++VE+ T
Sbjct: 2582 ----NQLREDELGSDISA----LTLRISELESQVVEMHT 2612
Score = 49.3 bits (116), Expect = 1e-05
Identities = 118/626 (18%), Positives = 248/626 (39%), Gaps = 114/626 (18%)
Query: 1 MEGERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLL 60
ME E E+ + +N++LEE+R G Q+Q A + + +Q N+ +
Sbjct: 160 MESELAGKQHEIEE-LNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQAR 218
Query: 61 KGRAQVQAEIEELQEQTRALDKQIQEWET---------------------RIFTHSKNVR 99
+ + + E EL EQ++ L Q Q+ + +I TH + +
Sbjct: 219 REKDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQLE 278
Query: 100 SPGFILD--QKVK---------IRRRIRILENQLDRVTCHFDNQLVRNA-ALREELDLLR 147
+L+ QK K ++ +I++ E + D+ + + + ++ + EEL+
Sbjct: 279 EQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKI 338
Query: 148 ID--------RNRYLNVDR---KLKKEIHHLHHLVSTLILSSTSAYAVR----EEAKAKM 192
I+ +++ D+ +L+++I + + + L T++ EE K M
Sbjct: 339 IEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLM 398
Query: 193 GLLRERAEKEEAQSEMEAQVLQRQILH----LEQL---------HHFLKLKNN-DRQPDP 238
G + E ++ S+ E ++QR LEQL +++K RQ
Sbjct: 399 GTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMA 458
Query: 239 DVLEKREKQAGEVAEGVWK----TSQERLVLCYEDALNKLSQLMGES------------- 281
+ E + + GE+ + T E + A+N+L+ + ++
Sbjct: 459 QMEEMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGL 518
Query: 282 --DPDLLVQKYLE--IEERNFAEFNF------INEQNLELEHVQEE---IKEMQEALVSA 328
+ +Q+ LE +EE +F+ I EQ +L + +++++ +VSA
Sbjct: 519 ILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSA 578
Query: 329 RASKDDQHL---------------LQEQQQKVLQQRMDKVHSEAERLEARFQ-DVRGQLE 372
S+ + L L++++ VL + + +E ERL + +L
Sbjct: 579 SESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELS 638
Query: 373 KLKADIQLLFTKAHCDSSMIDDLLGVKTSMGDRDMGLFLSLIEKRLVELLTVQAFLHAQS 432
KLK D+++ + + + D LG+ + GL + +K + Q+
Sbjct: 639 KLKEDLEI---EHRINIEKLKDNLGIHYK--QQIDGLQNEMSQKIETMQFEKDNLITKQN 693
Query: 433 FTSLADAALLVLGQSLEDLPKKMAPLQPPDTLEDPPGFEASDDYPMSREELLSQVEKLVE 492
L + L L QSL + + LQ + ++ + + E+ + +++ E
Sbjct: 694 QLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTE 753
Query: 493 LQEQAEAQRQKDLAAAAAKLDGTLSV 518
L E+ +++ DL A+L+ S+
Sbjct: 754 LLEKQMKEKENDLQEKFAQLEAENSI 779
Score = 47.0 bits (110), Expect = 6e-05
Identities = 73/396 (18%), Positives = 172/396 (43%), Gaps = 50/396 (12%)
Query: 2 EGERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLK 61
E ER + +E+ Q++ +QL+ + R + + ++ N +K ++ + LL
Sbjct: 2077 EHERDVFQQEI-QKLEQQLKVVPRFQPISEHQTREVEQLANHLK-----EKTDKCSELLL 2130
Query: 62 GRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKN-----VRSPGFILDQKVKIRR--- 113
+ Q+Q +I+E E+ L+ +++E E + + P L+ +++ R
Sbjct: 2131 SKEQLQRDIQERNEEIEKLEFRVRELEQALLVEDRKHFGAVEAKPELSLEVQLQAERDAI 2190
Query: 114 -----RIRILENQLDRVTCHFDNQLVRNAALREELDLLRID---RNRYLNVDRKL-KKEI 164
I LE QL++ +N+ L +L++ + + R + L + KL K ++
Sbjct: 2191 DRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDM 2250
Query: 165 HHLHHLVSTLILSSTSAYAVR--------EEAKAKMGLLRERAEKEEAQSEM--EAQVLQ 214
L + ST V +E + ++ L E+ K + Q ++ + +V++
Sbjct: 2251 EKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIE 2310
Query: 215 RQILHLEQLHHFLKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKL 274
+ + L ++ +D++ V RE++ ++ E + K QE + + ++N
Sbjct: 2311 EKNELIRDLETQIECLMSDQE---CVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAH 2367
Query: 275 SQLMGESDP-----DLLVQKYLEIEERNFAEFNFINEQNLELEHVQEE----IKEMQEAL 325
S L E+D D+++ + L +E+ + NE+ +++V +E + ++ + L
Sbjct: 2368 S-LSEEADSLKHQLDVVIAEKLALEQ----QVETANEEMTFMKNVLKETNFKMNQLTQEL 2422
Query: 326 VSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLE 361
S + ++ +Q + + +D + + LE
Sbjct: 2423 FSLKRERESVEKIQSIPENSVNVAIDHLSKDKPELE 2458
Score = 45.1 bits (105), Expect = 2e-04
Identities = 85/420 (20%), Positives = 175/420 (41%), Gaps = 44/420 (10%)
Query: 9 SKEVHQRIN---KQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQ 65
S+E+ +IN K++E +R+ E+ +G L+ ++ Q + + L + Q E + L + AQ
Sbjct: 714 SEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELL-EKQMKEKENDLQEKFAQ 772
Query: 66 VQAEIEELQEQTRALDKQIQ------EWETRIFTHSKNVRSPGFILDQKVKI-------- 111
++AE L+++ + L+ ++ + E IF S +S + +++++I
Sbjct: 773 LEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDL 832
Query: 112 -RRRIRI---LENQLDRVTCHFDNQLVRNAALREEL--------DLLRIDRNRYLNVDRK 159
++ I++ +E Q + + N V L+EE DL + L K
Sbjct: 833 KQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSK 892
Query: 160 LK--KEIHHLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQI 217
LK E HL + T + +S + + A+ + E EK+ + + +V +R+
Sbjct: 893 LKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREK 952
Query: 218 LHLEQLHHFLKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQL 277
L L Q L + + + L + K + E V +E ++ + +
Sbjct: 953 LELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINHNRAENVQSC 1012
Query: 278 MGESDPDLLVQKYLEIEERNF-AEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQH 336
++ L+ + + R + +N+ E + E K E + SK +Q
Sbjct: 1013 --DTQVSSLLDGVVTMTSRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQL 1070
Query: 337 LL-------QEQQQKVLQ-QRMDKVHSEAERLEARFQDVRGQLEKLKADIQLLFTKAHCD 388
+L +E + Q DK+ E L++ D+R Q+E + + L+++ H D
Sbjct: 1071 ILDHLPSVTKESSLRATQPSENDKLQKELNVLKSEQNDLRLQMEAQRICLSLVYS-THVD 1129
Score = 38.9 bits (89), Expect = 0.016
Identities = 71/377 (18%), Positives = 157/377 (41%), Gaps = 52/377 (13%)
Query: 26 LEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQVQAEIEELQEQTRALDKQIQ 85
L E++ L Q++ + +KR ++S++ + + L Q Q+++ E+Q + ++ +
Sbjct: 3083 LSEIQA-LHAQMNGRKITLKREQESEK-PSQELLEYNIQQKQSQMLEMQVELSSMKDRAT 3140
Query: 86 EWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLDRVTCHFDNQLVRNAALREELDL 145
E + ++ + V L+++L + + L +EL+
Sbjct: 3141 ELQEQLSSEKMVVAE-----------------LKSELAQTKLELETTLKAQHKHLKELEA 3183
Query: 146 LRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQ 205
R++ + E+H L+ +++ S E+ KAK+G ER ++E
Sbjct: 3184 FRLEV-------KDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELED 3236
Query: 206 SEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPDV------LEKREKQAGEVAEGVWKTS 259
+ + +++ L L L K N+ Q + + E+Q + V S
Sbjct: 3237 LKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLES 3296
Query: 260 QERLVLCYEDALNKLSQL---------MGESDP-----DLLVQKYLEIEERNFAEFNFIN 305
++ + L++ +L G+S P DLL + ++EE++ +N
Sbjct: 3297 EKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLN 3356
Query: 306 E-QNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLEARF 364
E + +L+ +Q + ++ V + + +Q E Q+K M ++ S+ E L+ +
Sbjct: 3357 ETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKK-----MHELQSKVEDLQRQL 3411
Query: 365 QDVRGQLEKLKADIQLL 381
++ R Q+ KL + Q L
Sbjct: 3412 EEKRQQVYKLDLEGQRL 3428
Score = 38.1 bits (87), Expect = 0.027
Identities = 78/416 (18%), Positives = 170/416 (40%), Gaps = 43/416 (10%)
Query: 104 ILDQKVKIRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKE 163
+L+ +++ + L + + ++ V L E + + L +L++
Sbjct: 1843 MLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRER 1902
Query: 164 IHHLHHLVSTLILSSTSAYAVREE-AKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQ 222
+H L + + A V + A K R+ EK + +E ++L L++
Sbjct: 1903 LHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASN-RLQE 1961
Query: 223 LHHFLKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERL-----VLCY----EDALNK 273
L + +R+ E + +AG V + + + +++ + V C D L K
Sbjct: 1962 LEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQK 2021
Query: 274 LSQLMGESDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKD 333
+ + E D + V +++E+E+ E+N EL ++++ + +++ L R D
Sbjct: 2022 QVKAL-EIDVEEQVSRFIELEQ----------EKNTELMDLRQQNQALEKQLEKMRKFLD 2070
Query: 334 DQHLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEKLKADIQLLFTKAHCDSSMID 393
+Q + +E ++ V QQ + K+ + ++ RFQ + E +++ L +
Sbjct: 2071 EQAIDREHERDVFQQEIQKLEQQL-KVVPRFQPIS---EHQTREVEQLANHLKEKTDKCS 2126
Query: 394 DLLGVKTSMGDRDMGLFLSLIEK------RLVELLTVQAFLHAQSFTSLADAALLVLGQS 447
+LL K + RD+ IEK L + L V+ H + + + +L V Q+
Sbjct: 2127 ELLLSKEQL-QRDIQERNEEIEKLEFRVRELEQALLVEDRKHFGAVEAKPELSLEVQLQA 2185
Query: 448 LEDLPKKMAPLQPPDTLEDPPGFEASDDYPMSREELLSQVEKLVELQEQAEAQRQK 503
D + ++ + REEL ++ E++ +L Q E Q+++
Sbjct: 2186 ERDAIDR----------KEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKE 2231
Score = 38.1 bits (87), Expect = 0.027
Identities = 45/217 (20%), Positives = 101/217 (46%), Gaps = 18/217 (8%)
Query: 191 KMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPDVLEKREKQAGE 250
K+ L RE+ ++ +Q +E + Q+Q LE +K+ + + E+ +
Sbjct: 3097 KITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATE----LQEQLSSEKMV 3152
Query: 251 VAEGVWKTSQERLVL-----CYEDALNKLS----QLMGESDPDLLVQKYLEIEERNFAEF 301
VAE + +Q +L L L +L ++ ++D L+ L E++ E
Sbjct: 3153 VAELKSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSREL 3212
Query: 302 NF-INEQNLEL----EHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSE 356
+ + ++ +L E +EE+++++ +L S + +LL EQQ+++L + K+ S+
Sbjct: 3213 QWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQ 3272
Query: 357 AERLEARFQDVRGQLEKLKADIQLLFTKAHCDSSMID 393
+A+ + +G+ +L+ ++ + SS +D
Sbjct: 3273 RMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLD 3309
Score = 34.7 bits (78), Expect = 0.29
Identities = 88/426 (20%), Positives = 176/426 (41%), Gaps = 70/426 (16%)
Query: 45 KRLRDSQRLENMDRLLKGRAQVQAEIEELQEQTRALDKQIQEWETR------IFTHSK-- 96
++L SQRL ++ LK Q EI L E+ ++L ++ ++ R I H++
Sbjct: 951 EKLELSQRLSDLSEQLK---QKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINHNRAE 1007
Query: 97 NVRS----PGFILDQKVKIRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNR 152
NV+S +LD V + R E + +V N + EE ++ D+
Sbjct: 1008 NVQSCDTQVSSLLDGVVTMTSRGA--EGSVSKV----------NKSFGEESKIMVEDKVS 1055
Query: 153 YLN--VDRKLKKEIHHLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEA 210
+ N V + K+E L HL S SS A E K + L ++E+ + + +MEA
Sbjct: 1056 FENMTVGEESKQEQLILDHLPSVTKESSLRATQPSENDKLQKELNVLKSEQNDLRLQMEA 1115
Query: 211 QVLQRQIL---HLEQLHHFL---------------------KLKNNDRQPDPDVLEKREK 246
Q + ++ H++Q+ ++ K+K + ++ + +
Sbjct: 1116 QRICLSLVYSTHVDQVREYMENEKDKALCSLKEELIFAQEEKIKELQKIHQLELQTMKTQ 1175
Query: 247 QAGEVAEGVWKTSQERLVLCYEDA---LNKLSQLMGESDPDLLVQKYLEIEERNFAEFNF 303
+ G+ + + + E+ L L ++GE L + ++ N ++
Sbjct: 1176 ETGDEGKPLHLLIGKLQKAVSEECSYFLQTLCSVLGEYYTPALKCEVNAEDKENSGDYIS 1235
Query: 304 INEQNLELEHVQEEIKEMQEALVSARASKDDQH----LLQEQQQKVLQQRMD--KVHSEA 357
NE + EL+ + E+++ QE + + +++ +LQ + K+ Q+ D K+
Sbjct: 1236 ENE-DPELQDYRYEVQDFQENMHTLLNKVTEEYNKLLVLQTRLSKIWGQQTDGMKLEFGE 1294
Query: 358 ERL---EARFQDVRGQLEKLKADIQLLFTKAHCDSSMIDDLLGVKTSMGDRDMGLFLSLI 414
E L E F + Q+ L+ DI + S + DL K +++ +S +
Sbjct: 1295 ENLPKEETEFLSIHSQMTNLE-DIDV---NHKSKLSSLQDLEKTKLEEQVQELESLISSL 1350
Query: 415 EKRLVE 420
+++L E
Sbjct: 1351 QQQLKE 1356
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 61.6 bits (148), Expect = 2e-09
Identities = 74/357 (20%), Positives = 160/357 (44%), Gaps = 39/357 (10%)
Query: 4 ERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQV-KRLRDSQRLENM------ 56
E+ +E ++I +Q E++RR EE+ + + ++ + + ++ +RLE M
Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEE 377
Query: 57 -DRLLKGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRI 115
R L+ + Q +I E QE+ R +++I+E E R +K R I +Q+ KIR +
Sbjct: 378 KIRELEEKMHEQEKIRE-QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 436
Query: 116 RILENQLDRVTCHFDNQLVRNAALREELDLL-------------------RIDRNRYLNV 156
+ + Q +++ + + +R R+E + + ++ +
Sbjct: 437 KKMWRQEEKI---HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
Query: 157 DRKLKKEIHHLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQ 216
+ K+ ++ +H + + E+ + + +RE+ EK Q EM + ++
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553
Query: 217 ILHLEQLHHFLKLKNND---RQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNK 273
E++ K++ + R+ + + E++EK E E +W+ QE + E+ + +
Sbjct: 554 GEQEEKMQEQEKMRRQEEKIREQEEKIREQKEK-IREQEEKIWE--QEEKIREQEEMMQE 610
Query: 274 LSQLMGESDPDLLVQ--KYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSA 328
+ M E + + Q K E EE+ + + EQ + L +E+++E QE L +A
Sbjct: 611 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 667
Score = 56.6 bits (135), Expect = 7e-08
Identities = 73/398 (18%), Positives = 169/398 (42%), Gaps = 61/398 (15%)
Query: 11 EVHQRINKQLEEI-----RRLEEVRGDLQVQISAAQNQVKRLRDSQ-RLENMDRLLKGRA 64
E+ R+N+Q EE +++E +Q Q + Q +++R+ + ++ + ++ +
Sbjct: 289 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 348
Query: 65 QVQAEIEEL----QEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILEN 120
+ EE+ +E+ R L++ + E E +I + + I +Q+ K + +I E
Sbjct: 349 EKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 408
Query: 121 QLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTS 180
+ + + A + + + +R + ++K+ ++ +H
Sbjct: 409 E---------KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK-------- 451
Query: 181 AYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHL-EQLHHFLKLKNNDRQP--D 237
+REE K R E+EE + E Q +I E++H K++ + +
Sbjct: 452 ---IREEEK--------RQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQ 500
Query: 238 PDVLEKREKQAGEVAEGVWKTS------------QERLVLCYEDALNKLSQLMGESDPDL 285
+ + +E++ E E +W+ QE + E+ + + + MGE + +
Sbjct: 501 EEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 560
Query: 286 LVQ--------KYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHL 337
Q K E EE+ + I EQ ++ +E+I+E +E + +Q
Sbjct: 561 QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620
Query: 338 LQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEKLK 375
+Q++ +Q++ +K+ + E++ + +R Q EK++
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 658
Score = 54.7 bits (130), Expect = 3e-07
Identities = 73/386 (18%), Positives = 168/386 (43%), Gaps = 60/386 (15%)
Query: 2 EGERRA---YSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQR--LENM 56
E E++A + + + + + Q+ IR L + +LQ+ + +Q+ VK+L R + +
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 57 DRLLKGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIR 116
K +++ + + Q + D+ I+E + +
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEE------------------------LTKERD 203
Query: 117 ILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNR-YLNVDRKLKKEIHHLHHLVSTLI 175
L +L R T + +NA L+E+L L+ +++ LNV ++LK+++ L+
Sbjct: 204 ALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNV-KELKRKLERAKLLLPQQQ 262
Query: 176 LSSTSAYAVRE--EAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNND 233
L + + + +E AK+ E E ++ + + + RQ +++ ++ +
Sbjct: 263 LQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 322
Query: 234 RQPDPDVLEKREKQAGEVAEGVWKTS-----QERLVLCYEDALNKLSQLMGESDPDLLVQ 288
+ + + ++E++ E +W+ QE ++ E+ + +L ++M E + +
Sbjct: 323 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKE-----E 377
Query: 289 KYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQ 348
K E+EE+ H QE+I+E +E + +Q QEQ+ K+ +Q
Sbjct: 378 KIRELEEK---------------MHEQEKIREQEEKRQEEEKIR-EQEKRQEQEAKMWRQ 421
Query: 349 RMDKVHSEAERLEARFQDVRGQLEKL 374
+K+ + E++ + + + Q EK+
Sbjct: 422 E-EKIREQEEKIREQEKKMWRQEEKI 446
Score = 30.8 bits (68), Expect = 4.2
Identities = 13/66 (19%), Positives = 38/66 (57%)
Query: 310 ELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRG 369
E +H+ +E++ + L + + + L +QQ++ + ++ +K+ E+++ + + +R
Sbjct: 266 EADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE 325
Query: 370 QLEKLK 375
Q EK++
Sbjct: 326 QEEKIR 331
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 60.1 bits (144), Expect = 7e-09
Identities = 121/569 (21%), Positives = 243/569 (42%), Gaps = 64/569 (11%)
Query: 1 MEGERRAYSKEVHQRINKQLEEIRRLEEVRG-----DLQVQISAAQNQVKRLRDSQRLEN 55
+E E+ ++KE+ + K E+ L+ + LQV Q ++++LR+ E
Sbjct: 594 LEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEK 653
Query: 56 MDRLLKGRAQV-QAEIEELQEQT-RALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRR 113
+ LLK + + QA IEE+ E+T LD + E E+ S+ +L + K+
Sbjct: 654 -ETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSE-------VLKARHKLEE 705
Query: 114 RIRILENQLDRVTCHFDNQL--VRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLV 171
+ +L++Q D++ + ++ +N ++ +++ ++ LK +I+ L L+
Sbjct: 706 ELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLL 765
Query: 172 S--TLILSSTSAYAVREEA--KAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFL 227
L A+ EA K G L++ + K + ++ ++ + EQL L
Sbjct: 766 KERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQ-L 824
Query: 228 KLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDL-- 285
+ K D + + +L K+ + + V T + + +D + +L + E + +
Sbjct: 825 QQKLLDLETERILLTKQVAEVEAQKKDVC-TELDAHKIQVQDLMQQLEKQNSEMEQKVKS 883
Query: 286 LVQKY-LEIEERNFAEFN----FINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQE 340
L Q Y ++E+ N + + ++N+ L+ + + KE++ A +D H+L E
Sbjct: 884 LTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNE 943
Query: 341 QQQ---KVLQQRMDKVHSEA----ERLEARFQDVRGQLEK--LKADIQLLFTKAHCDSSM 391
+ + K +++M+KV +A E L+ + D +L+K ++L + ++ M
Sbjct: 944 EYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKM 1003
Query: 392 IDDLLGVKTSMGDRDMGLFLSLIEKRLVELLTVQAFLHAQSFTSLADAALLVLGQSLEDL 451
++ + S G D L +K +E LT +H + + L Q E+L
Sbjct: 1004 LE--MAQANSAGISDAVSRLETNQKEQIESLTE---VHRRELNDVISIWEKKLNQQAEEL 1058
Query: 452 -----------PKKMAPLQPPDTLEDPPGFEASDDYPMSREELLSQVEKLVELQEQAE-- 498
+++A L+ L E + + +EE + Q L ELQEQ +
Sbjct: 1059 QEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQK 1118
Query: 499 -------AQRQKDLAAAAAKLDGTLSVDL 520
AQ + L A KL+ L+ L
Sbjct: 1119 SAHVNSLAQDETKLKAHLEKLEVDLNKSL 1147
Score = 50.4 bits (119), Expect = 5e-06
Identities = 85/396 (21%), Positives = 171/396 (43%), Gaps = 46/396 (11%)
Query: 4 ERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGR 63
E+ A +++H++ E R+ +E+ LQ + Q Q+K + + E + +
Sbjct: 476 EQIAKLQKLHEK-----ELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKE 530
Query: 64 AQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLD 123
Q +EEL+ Q +A I T S+N + + R RI LE+ L+
Sbjct: 531 QQESLALEELELQKKA-----------ILTESENKLRD--LQQEAETYRTRILELESSLE 577
Query: 124 RVTCHFDNQLVRNAALREELDLLRIDRNRYLNV-DRKLKKEIHHLHHLVSTLILSSTSAY 182
+ NQ + L L+ + N+ + V K K E+ L H L +
Sbjct: 578 KSLQENKNQ---SKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA--LWTEKLQ 632
Query: 183 AVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPDVLE 242
++++ + +M LRE+ E+E+ + +++ + H+E+++ K + +Q + LE
Sbjct: 633 VLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQ--AHIEEMNEKTLEKLDVKQTE---LE 687
Query: 243 KREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLM----------GESDPDLLVQKY-L 291
+ EV + K +E VL +D +K+ Q + + D +++++ +
Sbjct: 688 SLSSELSEVLKARHKLEEELSVL--KDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEV 745
Query: 292 EIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARAS-KDDQHLLQEQQQK--VLQQ 348
I+ A + IN+ L L+ + +KE Q + + A K + LQ+ K V Q
Sbjct: 746 SIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQS 805
Query: 349 RMDKVHSEAERLEARFQDVRGQLEKLKADIQLLFTK 384
H + + E + ++ +L L+ + ++L TK
Sbjct: 806 YQSATHEQTKAYEEQLAQLQQKLLDLETE-RILLTK 840
Score = 39.3 bits (90), Expect = 0.012
Identities = 81/448 (18%), Positives = 175/448 (39%), Gaps = 81/448 (18%)
Query: 22 EIRRLEEVRGDLQV-------QISAAQNQVKRLRDSQRLENMDRLLKGRAQVQAEIEELQ 74
++R+L E + L + Q+ +NQ+K ++ +++ L+ + +Q E Q
Sbjct: 1277 QLRQLTEEQNTLNISFQQATHQLEEKENQIKSMK-----ADIESLVTEKEALQKEGGNQQ 1331
Query: 75 EQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLDRVTCHFDNQLV 134
+ + I + + + S+N+ + + ++ + + I L QL + N +
Sbjct: 1332 QAASEKESCITQLKKEL---SENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSI- 1387
Query: 135 RNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSAYAVREEAKAKMGL 194
+L E+ + R +Y +L ++ L V TL SA ++ K
Sbjct: 1388 ---SLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSE 1444
Query: 195 LRERAEKEEAQSEMEAQVLQRQIL------------------HLEQLHHFLKLKNNDRQP 236
+++A+ Q + + LQ Q+ L+Q + + +
Sbjct: 1445 WKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMED 1504
Query: 237 DPDVLEKREK--------QAGEVAE----------------GVWKTSQERLVLCYEDALN 272
D +EK+E Q + E V K ++ + +++ +
Sbjct: 1505 DKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQ 1564
Query: 273 KLS--QLMGESDPDLLVQ---KYLEIEERNFAEFNFINEQNLELEHVQ-------EEIKE 320
KL Q +GE + + + K L +E + ++ + + ELEHV EE+K
Sbjct: 1565 KLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKA 1624
Query: 321 MQEALVSARASKDDQHLLQEQQQKV-------LQQRMDKVHSEAERLEARFQDVRGQLEK 373
+++ L S A+K + L ++ +QK+ L Q +K + E+ ++ +L++
Sbjct: 1625 LEDRLESESAAKLAE-LKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQE 1683
Query: 374 LKADIQLLFTKAHCDSSMIDDLLGVKTS 401
+ ++ +L K S + L V S
Sbjct: 1684 REREVHILEEKLKSVESSQSETLIVPRS 1711
Score = 36.6 bits (83), Expect = 0.077
Identities = 75/390 (19%), Positives = 164/390 (42%), Gaps = 47/390 (12%)
Query: 9 SKEVHQRINKQL-EEIRRLEEVRGDLQVQISAAQNQVK----RLRDSQRLENMDRLLKGR 63
+KE+ + + K+L ++ +L++ + +++S + Q + + D + +
Sbjct: 963 AKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLE 1022
Query: 64 AQVQAEIEELQE-QTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQL 122
+ +IE L E R L+ I WE ++ ++ ++ I Q+ + + + L+ ++
Sbjct: 1023 TNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKE--QEVAELKQKI 1080
Query: 123 DRVTCHFDNQLVRNAALREELDLLRIDRNRYLN-VDRKLKKEIHHLHHLVSTLILSSTSA 181
C + L+EE + ++ LN + +LK++ H++ L
Sbjct: 1081 LLFGCEKEEMNKEITWLKEE----GVKQDTTLNELQEQLKQKSAHVNSLA---------- 1126
Query: 182 YAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPDVL 241
++E K K L E+ E + +S E LQ Q++ L+ L K K ++ L
Sbjct: 1127 ---QDETKLKAHL--EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSE-------L 1174
Query: 242 EKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGES--DPDLLVQKYLEIEERNFA 299
+ K E + + K+S E+ ED + +L E D+ +K + E
Sbjct: 1175 TSKLKTTDEEFQSL-KSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTN 1233
Query: 300 EFNFINEQNLE-----LEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVH 354
E I+ + H Q +++EAL+ + + E Q + L + + ++
Sbjct: 1234 ELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSEL----EAQLRQLTEEQNTLN 1289
Query: 355 SEAERLEARFQDVRGQLEKLKADIQLLFTK 384
++ + ++ Q++ +KADI+ L T+
Sbjct: 1290 ISFQQATHQLEEKENQIKSMKADIESLVTE 1319
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 59.7 bits (143), Expect = 9e-09
Identities = 124/559 (22%), Positives = 234/559 (41%), Gaps = 66/559 (11%)
Query: 4 ERRAYSKEVHQRINKQLEEIRR----LEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRL 59
E R + + + +QLE+ +R LE+ + L+ + N+VK L L+
Sbjct: 1189 EMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVL-----LQGKGDS 1243
Query: 60 LKGRAQVQAEIEELQ---EQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKV-KIRRRI 115
R +V+A+++ELQ + + ++ + T++ NV D K K+ +
Sbjct: 1244 EHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDF 1303
Query: 116 RILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLI 175
LE+QL + + +L +L + ++N + + ++ H+L ++TL
Sbjct: 1304 SALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATL- 1362
Query: 176 LSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQ 235
++++ + +G L E AE+ + + LQ+ + L Q H ++
Sbjct: 1363 --HAQVADMKKKMEDSVGCL-ETAEEVKRK-------LQKDLEGLSQRHE-------EKV 1405
Query: 236 PDPDVLEK-REKQAGEVAEGVWKTSQERLVLC-YEDALNKLSQLMGESDPDLLVQKYLEI 293
D LEK + + E+ + + +R C E K QL+ E + KY E
Sbjct: 1406 AAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKT--ISAKYAEE 1463
Query: 294 EERNFAE--------------FNFINEQNLELEHVQEEIKEMQEALVSARASKDDQ---- 335
+R AE EQ ELE + ++ + E L+S SKDD
Sbjct: 1464 RDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMS---SKDDVGKSV 1520
Query: 336 HLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEKLKADIQLLFTKAHCDSSMIDDL 395
H L E+ ++ L+Q+++++ ++ E LE Q +L+ ++Q + + D D+
Sbjct: 1521 HEL-EKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQ 1579
Query: 396 LGVKTSMGDRDMG-LFLSLIEKRLVELLTVQAFLHAQSFTSLADAALLVLGQSLEDLPKK 454
K R + + L ++R + V A + +A + ++ ++ K+
Sbjct: 1580 SEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQ 1639
Query: 455 MAPLQPPDTLEDPPGFEASDDYPMSREELLSQV---EKLVELQEQAEAQRQKDLAAA-AA 510
+ LQ ++D DD SREE+L+Q EK ++ E Q Q++LAAA A
Sbjct: 1640 LRKLQAQ--MKDC--MRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERA 1695
Query: 511 KLDGTLSVDLASTQRAGSS 529
K D + + A SS
Sbjct: 1696 KRQAQQERDELADEIANSS 1714
Score = 56.2 bits (134), Expect = 9e-08
Identities = 94/454 (20%), Positives = 194/454 (42%), Gaps = 70/454 (15%)
Query: 11 EVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRL-RDSQRLENMDRLLKGRA-QVQA 68
E + ++ E+ + L +++ + I+ + +++R + Q LE R L+G + +
Sbjct: 1003 EFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSD 1062
Query: 69 EIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLDRVTCH 128
+I ELQ Q L Q+ + E + V QK ++IR LE+Q+
Sbjct: 1063 QIAELQAQIAELKMQLAKKEEELQAALARVEEEAA---QKNMALKKIRELESQISE---- 1115
Query: 129 FDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSAYAVREEA 188
L+E+L+ R RN+ R L +E+ L + + S+ + +R +
Sbjct: 1116 ----------LQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKR 1165
Query: 189 KAKMGLLRERAEKEEAQSEMEAQVLQRQILH-------LEQLHHFLKLK----------N 231
+ ++ +L++ E EEA++ EAQ+ + + H EQL ++K
Sbjct: 1166 EQEVNILKKTLE-EEAKTH-EAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLE 1223
Query: 232 NDR-----------QPDPDVLEKREKQAGEVAEGVWKTSQ-ERLVLCYEDALNKL----- 274
N+R Q D KR+K ++ E K ++ ER+ D + KL
Sbjct: 1224 NERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELD 1283
Query: 275 --SQLMGESD--PDLLVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARA 330
+ L+ +SD L + + +E + + E+N + + ++K++++ S R
Sbjct: 1284 NVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFRE 1343
Query: 331 SKDDQHLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLE-------KLKADIQLLFT 383
++ +E+ + L++++ +H++ ++ + +D G LE KL+ D++ L
Sbjct: 1344 QLEE----EEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQ 1399
Query: 384 KAHCDSSMIDDLLGVKTSMGDRDMGLFLSLIEKR 417
+ + D L KT + L + L +R
Sbjct: 1400 RHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQR 1433
Score = 56.2 bits (134), Expect = 9e-08
Identities = 87/418 (20%), Positives = 171/418 (40%), Gaps = 57/418 (13%)
Query: 4 ERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGR 63
ER E ++ K L R LEE + +++RL R E M+ L+ +
Sbjct: 1463 ERDRAEAEAREKETKALSLARALEEAMEQ--------KAELERLNKQFRTE-MEDLMSSK 1513
Query: 64 AQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLD 123
V + EL++ RAL++Q++E +T++ +++ D K+++ ++ ++ Q +
Sbjct: 1514 DDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATE---DAKLRLEVNLQAMKAQFE 1570
Query: 124 RVTCHFD-------NQLVRNA-ALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLI 175
R D QLVR + EL+ R R+ + +KL+ ++ L + +
Sbjct: 1571 RDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSAN 1630
Query: 176 LSSTSAYAVREEAKAKM---------------GLLRERAEKEEAQSEMEAQVLQRQILHL 220
+ A + +A+M +L + E E+ MEA+++Q Q
Sbjct: 1631 KNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQ---- 1686
Query: 221 EQLHHFLKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGE 280
E+L + K +Q ++ ++ +G+ A + + RL +L + G
Sbjct: 1687 EELAAAERAKRQAQQERDELADEIANSSGKGALAL--EEKRRLEARIAQLEEELEEEQGN 1744
Query: 281 SD--PDLLVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLL 338
++ D L + L+I++ N + NLE H Q+ Q+ R +K+ + L
Sbjct: 1745 TELINDRLKKANLQIDQIN-------TDLNLERSHAQKNENARQQL---ERQNKELKVKL 1794
Query: 339 QEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEKLKADIQLLFTKAHCDSSMIDDLL 396
QE + V K + LEA+ + QL+ + Q + + D+L
Sbjct: 1795 QEMEGTV----KSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVL 1848
Score = 32.0 bits (71), Expect = 1.9
Identities = 68/303 (22%), Positives = 122/303 (40%), Gaps = 43/303 (14%)
Query: 237 DPDVLEKREKQ-AGEVAEGVWKTSQERLV---LCYEDALNKLSQLMGESDP--DLLVQKY 290
+ ++++ REKQ A E +T Q +L+ L ++ L ++L E++ L K
Sbjct: 851 EEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKK 910
Query: 291 LEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQ----------- 339
E+EE + E+ +H+Q E K+MQ+ + +++ +
Sbjct: 911 QELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTE 970
Query: 340 ------EQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEKLKADIQLLFTKAHCDSSMID 393
E++Q +L+ + K+ E + LE R + L + + + L + +MI
Sbjct: 971 AKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMIT 1030
Query: 394 DLLGVKTSMGDRDMGLFLSLIEKRLVELLTVQAFLHAQSFTSLADAALLVLGQSLE---D 450
DL +R L EK+ EL + L S T L+D + Q E
Sbjct: 1031 DL-------EER-----LRREEKQRQELEKTRRKLEGDS-TDLSDQIAELQAQIAELKMQ 1077
Query: 451 LPKKMAPLQPPDTLEDPPGFEASDDYPMSREELLSQVEKLVELQEQAEAQRQKDLAAAAA 510
L KK LQ + E + M+ +++ ++ ELQE E++R A
Sbjct: 1078 LAKKEEELQAALARVE----EEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQ 1133
Query: 511 KLD 513
K D
Sbjct: 1134 KRD 1136
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 59.3 bits (142), Expect = 1e-08
Identities = 72/389 (18%), Positives = 178/389 (45%), Gaps = 34/389 (8%)
Query: 6 RAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQ 65
R ++E+ ++ + EE++ +E + ++Q+ I + +++ + E R +G+ +
Sbjct: 3 RITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVR 62
Query: 66 VQ-AEIEELQEQTRALDKQIQEWETRIFTHSKNVRSP-GFILDQKVKIRRRIRILENQLD 123
Q ++ E + Q R + Q++E E ++ VR G + +Q+ ++R + + Q
Sbjct: 63 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 122
Query: 124 RVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSAYA 183
+V + +RE+ +R + + +++++ +
Sbjct: 123 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ---------- 172
Query: 184 VREEAKAKMGLLRERA----EKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPD 239
VRE+ G +RE+ E+E E E Q+ +++ EQ K + + + +
Sbjct: 173 VREQE----GQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQE-E 227
Query: 240 VLEKREKQAGEVAEGVWKTS-----QERLVLCYEDALNKLSQLMGESDPDLLVQK-YLEI 293
+ K+E+Q GE E V K QE + E+ + + + M E + +L QK E
Sbjct: 228 QMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQ 287
Query: 294 EERNFAEFNFINEQNLELEHVQEEIKEMQEAL--VSARASKDDQHLLQE-----QQQKVL 346
EE+ + + EQ ++ +E+++E +E + + K ++ + ++ +Q++ +
Sbjct: 288 EEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQM 347
Query: 347 QQRMDKVHSEAERLEARFQDVRGQLEKLK 375
++ +++ + E+++ + + VR Q E+++
Sbjct: 348 WKQEEQMGEQEEQMQKQEEQVRKQEEQMR 376
Score = 48.5 bits (114), Expect = 2e-05
Identities = 62/384 (16%), Positives = 167/384 (43%), Gaps = 35/384 (9%)
Query: 2 EGERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLK 61
EG+ R +V ++ + E+ ++ E G ++ Q + Q ++R+ E R +
Sbjct: 58 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ---EGQVREQE 114
Query: 62 GRAQVQ-AEIEELQEQTRALDKQIQEWETRIFTHSKNVRSP-GFILDQKVKIRRRIRILE 119
G+ + Q ++ E + Q R + Q++E E ++ VR G + +Q+ ++R + +
Sbjct: 115 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 174
Query: 120 NQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSST 179
Q +V + + E+ + + + +++K+ + +
Sbjct: 175 EQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQM----- 229
Query: 180 SAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLK------LKNND 233
+ + +MG E+ +K+E Q + + + +++Q + + ++ LK +
Sbjct: 230 ------RKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKE 283
Query: 234 RQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLEI 293
+ + ++E+Q E E + QE + E+ + + + MG+ + + QK
Sbjct: 284 QTEQEEQTGEQEEQMREQEEQM--REQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMW 341
Query: 294 EERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQ---QQKVLQQRM 350
E++ + + E + E+ ++MQ+ R ++ +EQ Q++ ++++
Sbjct: 342 EQKE--------QMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQE 393
Query: 351 DKVHSEAERLEARFQDVRGQLEKL 374
+++ + E++ + + +R Q E++
Sbjct: 394 EQMGEQKEQMGEQKEQMREQEEQM 417
Score = 43.5 bits (101), Expect = 6e-04
Identities = 52/286 (18%), Positives = 120/286 (41%), Gaps = 55/286 (19%)
Query: 3 GERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKG 62
GE+ E +++ +Q E++++ EE G+ + Q+ R ++ Q E +++ K
Sbjct: 195 GEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQM--------RKQEEQMGEQEEQVQKQ 246
Query: 63 RAQVQAEIEEL---QEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILE 119
QVQ + E++ +EQ R ++Q++E E ++ + +Q+ ++R + E
Sbjct: 247 EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQ----E 302
Query: 120 NQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSST 179
Q+ RE+ + +R + + ++ K+ +
Sbjct: 303 EQM-----------------REQEEQMREQEEQMREQEEQMGKQEEQMW----------- 334
Query: 180 SAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPD 239
E K +M +E+ K+E Q + + +Q+Q + + ++ + + +
Sbjct: 335 -------EQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEE 387
Query: 240 VLEKREKQAGEVAEGVWK-----TSQERLVLCYEDALNKLSQLMGE 280
+ K+E+Q GE E + + QE + ++ + K + MGE
Sbjct: 388 QMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGE 433
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 59.3 bits (142), Expect = 1e-08
Identities = 89/440 (20%), Positives = 187/440 (42%), Gaps = 71/440 (16%)
Query: 10 KEVHQRINKQLEEIRRLEE-VRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRA---- 64
KE+ Q+ ++ EE L+E ++ + ++ A + +V+ Q LE + ++ R
Sbjct: 876 KELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEE 935
Query: 65 ----QVQAEIEELQEQTRALDKQIQEWET--------RIFTHSKNVRSPGFIL---DQKV 109
Q+QAE +++ +Q L++Q++E E ++ +K + IL DQ
Sbjct: 936 DRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNN 995
Query: 110 KIRRRIRILENQLDRVTCHF--DNQLVRN------------AALREELDLLRIDRNRYLN 155
K+ + ++LE ++ +T + + + +N + L L R
Sbjct: 996 KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEK 1055
Query: 156 VDRKLKKEIHHLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQR 215
+ RKL+ + H ++ L + A+ KM L ++ E + A + ++ ++ Q+
Sbjct: 1056 LKRKLEGDASDFHEQIADL---------QAQIAELKMQLAKKEEELQAALARLDDEIAQK 1106
Query: 216 Q--ILHLEQLHHFLKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNK 273
+ + +L + D + K EKQ ++ E + E L ED L+
Sbjct: 1107 NNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL-----EALKTELEDTLDS 1161
Query: 274 LS---QLMGESDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQ--EEIKEMQEALVSA 328
+ +L + + ++ V K EE E Q + +H Q EE+ E E A
Sbjct: 1162 TATQQELRAKREQEVTVLKKALDEETRSHEAQV---QEMRQKHAQAVEELTEQLEQFKRA 1218
Query: 329 RASKDDQHLLQEQQQ-------KVLQQRMDKVHSEAERLEARFQDVRGQL---EKLKADI 378
+A+ D E++ +VL Q +V + ++LEA+ Q+++ + E+ +A++
Sbjct: 1219 KANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAEL 1278
Query: 379 QLLFTKAHCDSSMIDDLLGV 398
K H + ++ + G+
Sbjct: 1279 N---DKVHKLQNEVESVTGM 1295
Score = 52.8 bits (125), Expect = 1e-06
Identities = 82/398 (20%), Positives = 173/398 (43%), Gaps = 58/398 (14%)
Query: 1 MEGERRAYSKE---VHQRIN-------KQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDS 50
M+ + SKE + +RI+ ++ E+ + L +++ + IS + ++K+ S
Sbjct: 990 MDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS 1049
Query: 51 -QRLENMDRLLKGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILD--- 106
Q LE + R L+G A + EQ L QI E + ++ + +++ LD
Sbjct: 1050 RQELEKLKRKLEGDAS------DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEI 1103
Query: 107 -QKVKIRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIH 165
QK ++IR LE + + L+E+LD R RN+ R L +E+
Sbjct: 1104 AQKNNALKKIRELEGHI--------------SDLQEDLDSERAARNKAEKQKRDLGEELE 1149
Query: 166 HLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILH-----L 220
L + + S+ + +R + + ++ +L++ ++E E + Q ++++
Sbjct: 1150 ALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT 1209
Query: 221 EQLHHFLKLKNNDRQPDPDVLEKREKQAGEV-----AEGVWKTSQERLVLCYEDALNKLS 275
EQL F + K N + + ++ AGE+ A+ + +++L ++ +K S
Sbjct: 1210 EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCS 1269
Query: 276 QLMGESDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQ 335
GE L K +++ + +NE + + +++ + L +D Q
Sbjct: 1270 D--GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQL------QDTQ 1321
Query: 336 HLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEK 373
LLQE+ ++ L V ++ +LE ++ QL++
Sbjct: 1322 ELLQEETRQKL-----NVSTKLRQLEEERNSLQDQLDE 1354
Score = 50.8 bits (120), Expect = 4e-06
Identities = 77/384 (20%), Positives = 162/384 (42%), Gaps = 34/384 (8%)
Query: 4 ERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGR 63
ER E ++ K L R LEE A+ +++R + E M+ L+ +
Sbjct: 1470 ERDRAEAEAREKETKALSLARALEEAL--------EAKEELERTNKMLKAE-MEDLVSSK 1520
Query: 64 AQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLD 123
V + EL++ RAL+ Q++E +T++ +++ D K+++ ++ L+ Q +
Sbjct: 1521 DDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE---DAKLRLEVNMQALKGQFE 1577
Query: 124 RVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLK----KEIHHLHHLVSTLILSST 179
R D Q N R +L + L +RK + L + L L +
Sbjct: 1578 RDLQARDEQ---NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1634
Query: 180 SAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQP--- 236
SA REEA ++ L +A+ ++ Q E+E R + F K N+++
Sbjct: 1635 SAIKGREEAIKQLRKL--QAQMKDFQRELEDARASRDEI-------FATAKENEKKAKSL 1685
Query: 237 DPDVLEKREKQAGEVAEGVWKTSQ-ERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEE 295
+ D+++ +E A AE K + E+ L E A + + + + L + ++EE
Sbjct: 1686 EADLMQLQEDLA--AAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEE 1743
Query: 296 RNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHS 355
E + + + ++ +++ L + R++ ++Q ++ ++ K+H
Sbjct: 1744 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 1803
Query: 356 EAERLEARFQDVRGQLEKLKADIQ 379
++++F+ LE A ++
Sbjct: 1804 MEGAVKSKFKSTIAALEAKIAQLE 1827
Score = 48.1 bits (113), Expect = 3e-05
Identities = 106/580 (18%), Positives = 228/580 (39%), Gaps = 76/580 (13%)
Query: 2 EGERRAYSKEVHQRINKQLEEI-----------RRLEEVRGDLQVQISAAQNQVKRLRDS 50
EG++R + KE+ + + +Q EE RL++ DL V + + V L
Sbjct: 1392 EGKKR-FQKEI-ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1449
Query: 51 QRLENMDRLLKGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVK 110
QR D+LL + ++ + +++ A + +E ET+ + ++ + L+ K +
Sbjct: 1450 QR--KFDQLLAEEKNISSKYADERDRAEA---EAREKETKALSLARALEEA---LEAKEE 1501
Query: 111 IRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHL 170
+ R ++L+ +++ + D+ L + L + ++++ L L
Sbjct: 1502 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL----------ETQMEEMKTQLEEL 1551
Query: 171 VSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLK 230
L + + + +A G + + Q+E + + LQRQ LH +
Sbjct: 1552 EDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ------LHEYETEL 1605
Query: 231 NNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKY 290
++R+ ++K G++ + + + + E+A+ +L +L + Q+
Sbjct: 1606 EDERKQRALAAAAKKKLEGDLKD--LELQADSAIKGREEAIKQLRKLQAQMKD---FQRE 1660
Query: 291 LEIEERNFAE-FNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQR 349
LE + E F E + + ++ ++ ++QE L +A ++ L +E+ + L
Sbjct: 1661 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASS 1720
Query: 350 M---DKVHSEAERLEARFQDVRGQLEKLKADIQLL---FTKAHCDSSMIDDLLGVKTSMG 403
+ + + E RLEAR + +LE+ + +++ + KA + + + L + S
Sbjct: 1721 LSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTA 1780
Query: 404 DRDM---------------------GLFLSLIEKRLVELLTVQAFLHAQSFTSLADAALL 442
++ G S + + L A L Q +
Sbjct: 1781 QKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAA 1840
Query: 443 VLGQSLEDLPKKMAPLQPPDTLEDPPGFEASDDYPMSR-EELLSQVEKLVELQEQAEAQR 501
+D K LQ D + ++ + +R ++L Q+E+ E ++ A R
Sbjct: 1841 TKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANR 1900
Query: 502 QK-----DLAAAAAKLDGTLSVDLASTQRAGSSTVLVPTR 536
+K D A + + G L S R G+ T VP+R
Sbjct: 1901 RKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSR 1940
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 59.3 bits (142), Expect = 1e-08
Identities = 89/440 (20%), Positives = 187/440 (42%), Gaps = 71/440 (16%)
Query: 10 KEVHQRINKQLEEIRRLEE-VRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRA---- 64
KE+ Q+ ++ EE L+E ++ + ++ A + +V+ Q LE + ++ R
Sbjct: 883 KELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEE 942
Query: 65 ----QVQAEIEELQEQTRALDKQIQEWET--------RIFTHSKNVRSPGFIL---DQKV 109
Q+QAE +++ +Q L++Q++E E ++ +K + IL DQ
Sbjct: 943 DRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNN 1002
Query: 110 KIRRRIRILENQLDRVTCHF--DNQLVRN------------AALREELDLLRIDRNRYLN 155
K+ + ++LE ++ +T + + + +N + L L R
Sbjct: 1003 KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEK 1062
Query: 156 VDRKLKKEIHHLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQR 215
+ RKL+ + H ++ L + A+ KM L ++ E + A + ++ ++ Q+
Sbjct: 1063 LKRKLEGDASDFHEQIADL---------QAQIAELKMQLAKKEEELQAALARLDDEIAQK 1113
Query: 216 Q--ILHLEQLHHFLKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNK 273
+ + +L + D + K EKQ ++ E + E L ED L+
Sbjct: 1114 NNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL-----EALKTELEDTLDS 1168
Query: 274 LS---QLMGESDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQ--EEIKEMQEALVSA 328
+ +L + + ++ V K EE E Q + +H Q EE+ E E A
Sbjct: 1169 TATQQELRAKREQEVTVLKKALDEETRSHEAQV---QEMRQKHAQAVEELTEQLEQFKRA 1225
Query: 329 RASKDDQHLLQEQQQ-------KVLQQRMDKVHSEAERLEARFQDVRGQL---EKLKADI 378
+A+ D E++ +VL Q +V + ++LEA+ Q+++ + E+ +A++
Sbjct: 1226 KANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAEL 1285
Query: 379 QLLFTKAHCDSSMIDDLLGV 398
K H + ++ + G+
Sbjct: 1286 N---DKVHKLQNEVESVTGM 1302
Score = 52.8 bits (125), Expect = 1e-06
Identities = 82/398 (20%), Positives = 173/398 (43%), Gaps = 58/398 (14%)
Query: 1 MEGERRAYSKE---VHQRIN-------KQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDS 50
M+ + SKE + +RI+ ++ E+ + L +++ + IS + ++K+ S
Sbjct: 997 MDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS 1056
Query: 51 -QRLENMDRLLKGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILD--- 106
Q LE + R L+G A + EQ L QI E + ++ + +++ LD
Sbjct: 1057 RQELEKLKRKLEGDAS------DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEI 1110
Query: 107 -QKVKIRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIH 165
QK ++IR LE + + L+E+LD R RN+ R L +E+
Sbjct: 1111 AQKNNALKKIRELEGHI--------------SDLQEDLDSERAARNKAEKQKRDLGEELE 1156
Query: 166 HLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILH-----L 220
L + + S+ + +R + + ++ +L++ ++E E + Q ++++
Sbjct: 1157 ALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT 1216
Query: 221 EQLHHFLKLKNNDRQPDPDVLEKREKQAGEV-----AEGVWKTSQERLVLCYEDALNKLS 275
EQL F + K N + + ++ AGE+ A+ + +++L ++ +K S
Sbjct: 1217 EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCS 1276
Query: 276 QLMGESDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQ 335
GE L K +++ + +NE + + +++ + L +D Q
Sbjct: 1277 D--GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQL------QDTQ 1328
Query: 336 HLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEK 373
LLQE+ ++ L V ++ +LE ++ QL++
Sbjct: 1329 ELLQEETRQKL-----NVSTKLRQLEEERNSLQDQLDE 1361
Score = 50.8 bits (120), Expect = 4e-06
Identities = 77/384 (20%), Positives = 162/384 (42%), Gaps = 34/384 (8%)
Query: 4 ERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGR 63
ER E ++ K L R LEE A+ +++R + E M+ L+ +
Sbjct: 1477 ERDRAEAEAREKETKALSLARALEEAL--------EAKEELERTNKMLKAE-MEDLVSSK 1527
Query: 64 AQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLD 123
V + EL++ RAL+ Q++E +T++ +++ D K+++ ++ L+ Q +
Sbjct: 1528 DDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE---DAKLRLEVNMQALKGQFE 1584
Query: 124 RVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLK----KEIHHLHHLVSTLILSST 179
R D Q N R +L + L +RK + L + L L +
Sbjct: 1585 RDLQARDEQ---NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1641
Query: 180 SAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQP--- 236
SA REEA ++ L +A+ ++ Q E+E R + F K N+++
Sbjct: 1642 SAIKGREEAIKQLRKL--QAQMKDFQRELEDARASRDEI-------FATAKENEKKAKSL 1692
Query: 237 DPDVLEKREKQAGEVAEGVWKTSQ-ERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEE 295
+ D+++ +E A AE K + E+ L E A + + + + L + ++EE
Sbjct: 1693 EADLMQLQEDLA--AAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEE 1750
Query: 296 RNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHS 355
E + + + ++ +++ L + R++ ++Q ++ ++ K+H
Sbjct: 1751 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 1810
Query: 356 EAERLEARFQDVRGQLEKLKADIQ 379
++++F+ LE A ++
Sbjct: 1811 MEGAVKSKFKSTIAALEAKIAQLE 1834
Score = 48.1 bits (113), Expect = 3e-05
Identities = 106/580 (18%), Positives = 228/580 (39%), Gaps = 76/580 (13%)
Query: 2 EGERRAYSKEVHQRINKQLEEI-----------RRLEEVRGDLQVQISAAQNQVKRLRDS 50
EG++R + KE+ + + +Q EE RL++ DL V + + V L
Sbjct: 1399 EGKKR-FQKEI-ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1456
Query: 51 QRLENMDRLLKGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVK 110
QR D+LL + ++ + +++ A + +E ET+ + ++ + L+ K +
Sbjct: 1457 QR--KFDQLLAEEKNISSKYADERDRAEA---EAREKETKALSLARALEEA---LEAKEE 1508
Query: 111 IRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHL 170
+ R ++L+ +++ + D+ L + L + ++++ L L
Sbjct: 1509 LERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL----------ETQMEEMKTQLEEL 1558
Query: 171 VSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLK 230
L + + + +A G + + Q+E + + LQRQ LH +
Sbjct: 1559 EDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ------LHEYETEL 1612
Query: 231 NNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKY 290
++R+ ++K G++ + + + + E+A+ +L +L + Q+
Sbjct: 1613 EDERKQRALAAAAKKKLEGDLKD--LELQADSAIKGREEAIKQLRKLQAQMKD---FQRE 1667
Query: 291 LEIEERNFAE-FNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQR 349
LE + E F E + + ++ ++ ++QE L +A ++ L +E+ + L
Sbjct: 1668 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASS 1727
Query: 350 M---DKVHSEAERLEARFQDVRGQLEKLKADIQLL---FTKAHCDSSMIDDLLGVKTSMG 403
+ + + E RLEAR + +LE+ + +++ + KA + + + L + S
Sbjct: 1728 LSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTA 1787
Query: 404 DRDM---------------------GLFLSLIEKRLVELLTVQAFLHAQSFTSLADAALL 442
++ G S + + L A L Q +
Sbjct: 1788 QKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAA 1847
Query: 443 VLGQSLEDLPKKMAPLQPPDTLEDPPGFEASDDYPMSR-EELLSQVEKLVELQEQAEAQR 501
+D K LQ D + ++ + +R ++L Q+E+ E ++ A R
Sbjct: 1848 TKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANR 1907
Query: 502 QK-----DLAAAAAKLDGTLSVDLASTQRAGSSTVLVPTR 536
+K D A + + G L S R G+ T VP+R
Sbjct: 1908 RKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSR 1947
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 59.3 bits (142), Expect = 1e-08
Identities = 89/440 (20%), Positives = 187/440 (42%), Gaps = 71/440 (16%)
Query: 10 KEVHQRINKQLEEIRRLEE-VRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRA---- 64
KE+ Q+ ++ EE L+E ++ + ++ A + +V+ Q LE + ++ R
Sbjct: 883 KELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEE 942
Query: 65 ----QVQAEIEELQEQTRALDKQIQEWET--------RIFTHSKNVRSPGFIL---DQKV 109
Q+QAE +++ +Q L++Q++E E ++ +K + IL DQ
Sbjct: 943 DRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNN 1002
Query: 110 KIRRRIRILENQLDRVTCHF--DNQLVRN------------AALREELDLLRIDRNRYLN 155
K+ + ++LE ++ +T + + + +N + L L R
Sbjct: 1003 KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEK 1062
Query: 156 VDRKLKKEIHHLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQR 215
+ RKL+ + H ++ L + A+ KM L ++ E + A + ++ ++ Q+
Sbjct: 1063 LKRKLEGDASDFHEQIADL---------QAQIAELKMQLAKKEEELQAALARLDDEIAQK 1113
Query: 216 Q--ILHLEQLHHFLKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNK 273
+ + +L + D + K EKQ ++ E + E L ED L+
Sbjct: 1114 NNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL-----EALKTELEDTLDS 1168
Query: 274 LS---QLMGESDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQ--EEIKEMQEALVSA 328
+ +L + + ++ V K EE E Q + +H Q EE+ E E A
Sbjct: 1169 TATQQELRAKREQEVTVLKKALDEETRSHEAQV---QEMRQKHAQAVEELTEQLEQFKRA 1225
Query: 329 RASKDDQHLLQEQQQ-------KVLQQRMDKVHSEAERLEARFQDVRGQL---EKLKADI 378
+A+ D E++ +VL Q +V + ++LEA+ Q+++ + E+ +A++
Sbjct: 1226 KANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAEL 1285
Query: 379 QLLFTKAHCDSSMIDDLLGV 398
K H + ++ + G+
Sbjct: 1286 N---DKVHKLQNEVESVTGM 1302
Score = 52.8 bits (125), Expect = 1e-06
Identities = 82/398 (20%), Positives = 173/398 (43%), Gaps = 58/398 (14%)
Query: 1 MEGERRAYSKE---VHQRIN-------KQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDS 50
M+ + SKE + +RI+ ++ E+ + L +++ + IS + ++K+ S
Sbjct: 997 MDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS 1056
Query: 51 -QRLENMDRLLKGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILD--- 106
Q LE + R L+G A + EQ L QI E + ++ + +++ LD
Sbjct: 1057 RQELEKLKRKLEGDAS------DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEI 1110
Query: 107 -QKVKIRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIH 165
QK ++IR LE + + L+E+LD R RN+ R L +E+
Sbjct: 1111 AQKNNALKKIRELEGHI--------------SDLQEDLDSERAARNKAEKQKRDLGEELE 1156
Query: 166 HLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILH-----L 220
L + + S+ + +R + + ++ +L++ ++E E + Q ++++
Sbjct: 1157 ALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT 1216
Query: 221 EQLHHFLKLKNNDRQPDPDVLEKREKQAGEV-----AEGVWKTSQERLVLCYEDALNKLS 275
EQL F + K N + + ++ AGE+ A+ + +++L ++ +K S
Sbjct: 1217 EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCS 1276
Query: 276 QLMGESDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQ 335
GE L K +++ + +NE + + +++ + L +D Q
Sbjct: 1277 D--GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQL------QDTQ 1328
Query: 336 HLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEK 373
LLQE+ ++ L V ++ +LE ++ QL++
Sbjct: 1329 ELLQEETRQKL-----NVSTKLRQLEEERNSLQDQLDE 1361
Score = 50.8 bits (120), Expect = 4e-06
Identities = 77/384 (20%), Positives = 162/384 (42%), Gaps = 34/384 (8%)
Query: 4 ERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGR 63
ER E ++ K L R LEE A+ +++R + E M+ L+ +
Sbjct: 1477 ERDRAEAEAREKETKALSLARALEEAL--------EAKEELERTNKMLKAE-MEDLVSSK 1527
Query: 64 AQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLD 123
V + EL++ RAL+ Q++E +T++ +++ D K+++ ++ L+ Q +
Sbjct: 1528 DDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE---DAKLRLEVNMQALKGQFE 1584
Query: 124 RVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLK----KEIHHLHHLVSTLILSST 179
R D Q N R +L + L +RK + L + L L +
Sbjct: 1585 RDLQARDEQ---NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1641
Query: 180 SAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQP--- 236
SA REEA ++ L +A+ ++ Q E+E R + F K N+++
Sbjct: 1642 SAIKGREEAIKQLRKL--QAQMKDFQRELEDARASRDEI-------FATAKENEKKAKSL 1692
Query: 237 DPDVLEKREKQAGEVAEGVWKTSQ-ERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEE 295
+ D+++ +E A AE K + E+ L E A + + + + L + ++EE
Sbjct: 1693 EADLMQLQEDLA--AAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEE 1750
Query: 296 RNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHS 355
E + + + ++ +++ L + R++ ++Q ++ ++ K+H
Sbjct: 1751 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 1810
Query: 356 EAERLEARFQDVRGQLEKLKADIQ 379
++++F+ LE A ++
Sbjct: 1811 MEGAVKSKFKSTIAALEAKIAQLE 1834
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 59.3 bits (142), Expect = 1e-08
Identities = 89/440 (20%), Positives = 187/440 (42%), Gaps = 71/440 (16%)
Query: 10 KEVHQRINKQLEEIRRLEE-VRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRA---- 64
KE+ Q+ ++ EE L+E ++ + ++ A + +V+ Q LE + ++ R
Sbjct: 876 KELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEE 935
Query: 65 ----QVQAEIEELQEQTRALDKQIQEWET--------RIFTHSKNVRSPGFIL---DQKV 109
Q+QAE +++ +Q L++Q++E E ++ +K + IL DQ
Sbjct: 936 DRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNN 995
Query: 110 KIRRRIRILENQLDRVTCHF--DNQLVRN------------AALREELDLLRIDRNRYLN 155
K+ + ++LE ++ +T + + + +N + L L R
Sbjct: 996 KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEK 1055
Query: 156 VDRKLKKEIHHLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQR 215
+ RKL+ + H ++ L + A+ KM L ++ E + A + ++ ++ Q+
Sbjct: 1056 LKRKLEGDASDFHEQIADL---------QAQIAELKMQLAKKEEELQAALARLDDEIAQK 1106
Query: 216 Q--ILHLEQLHHFLKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNK 273
+ + +L + D + K EKQ ++ E + E L ED L+
Sbjct: 1107 NNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL-----EALKTELEDTLDS 1161
Query: 274 LS---QLMGESDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQ--EEIKEMQEALVSA 328
+ +L + + ++ V K EE E Q + +H Q EE+ E E A
Sbjct: 1162 TATQQELRAKREQEVTVLKKALDEETRSHEAQV---QEMRQKHAQAVEELTEQLEQFKRA 1218
Query: 329 RASKDDQHLLQEQQQ-------KVLQQRMDKVHSEAERLEARFQDVRGQL---EKLKADI 378
+A+ D E++ +VL Q +V + ++LEA+ Q+++ + E+ +A++
Sbjct: 1219 KANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAEL 1278
Query: 379 QLLFTKAHCDSSMIDDLLGV 398
K H + ++ + G+
Sbjct: 1279 N---DKVHKLQNEVESVTGM 1295
Score = 52.8 bits (125), Expect = 1e-06
Identities = 82/398 (20%), Positives = 173/398 (43%), Gaps = 58/398 (14%)
Query: 1 MEGERRAYSKE---VHQRIN-------KQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDS 50
M+ + SKE + +RI+ ++ E+ + L +++ + IS + ++K+ S
Sbjct: 990 MDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS 1049
Query: 51 -QRLENMDRLLKGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILD--- 106
Q LE + R L+G A + EQ L QI E + ++ + +++ LD
Sbjct: 1050 RQELEKLKRKLEGDAS------DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEI 1103
Query: 107 -QKVKIRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIH 165
QK ++IR LE + + L+E+LD R RN+ R L +E+
Sbjct: 1104 AQKNNALKKIRELEGHI--------------SDLQEDLDSERAARNKAEKQKRDLGEELE 1149
Query: 166 HLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILH-----L 220
L + + S+ + +R + + ++ +L++ ++E E + Q ++++
Sbjct: 1150 ALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT 1209
Query: 221 EQLHHFLKLKNNDRQPDPDVLEKREKQAGEV-----AEGVWKTSQERLVLCYEDALNKLS 275
EQL F + K N + + ++ AGE+ A+ + +++L ++ +K S
Sbjct: 1210 EQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCS 1269
Query: 276 QLMGESDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQ 335
GE L K +++ + +NE + + +++ + L +D Q
Sbjct: 1270 D--GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQL------QDTQ 1321
Query: 336 HLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEK 373
LLQE+ ++ L V ++ +LE ++ QL++
Sbjct: 1322 ELLQEETRQKL-----NVSTKLRQLEEERNSLQDQLDE 1354
Score = 50.8 bits (120), Expect = 4e-06
Identities = 77/384 (20%), Positives = 162/384 (42%), Gaps = 34/384 (8%)
Query: 4 ERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGR 63
ER E ++ K L R LEE A+ +++R + E M+ L+ +
Sbjct: 1470 ERDRAEAEAREKETKALSLARALEEAL--------EAKEELERTNKMLKAE-MEDLVSSK 1520
Query: 64 AQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLD 123
V + EL++ RAL+ Q++E +T++ +++ D K+++ ++ L+ Q +
Sbjct: 1521 DDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATE---DAKLRLEVNMQALKGQFE 1577
Query: 124 RVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLK----KEIHHLHHLVSTLILSST 179
R D Q N R +L + L +RK + L + L L +
Sbjct: 1578 RDLQARDEQ---NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQAD 1634
Query: 180 SAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQP--- 236
SA REEA ++ L +A+ ++ Q E+E R + F K N+++
Sbjct: 1635 SAIKGREEAIKQLRKL--QAQMKDFQRELEDARASRDEI-------FATAKENEKKAKSL 1685
Query: 237 DPDVLEKREKQAGEVAEGVWKTSQ-ERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEE 295
+ D+++ +E A AE K + E+ L E A + + + + L + ++EE
Sbjct: 1686 EADLMQLQEDLA--AAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEE 1743
Query: 296 RNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHS 355
E + + + ++ +++ L + R++ ++Q ++ ++ K+H
Sbjct: 1744 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 1803
Query: 356 EAERLEARFQDVRGQLEKLKADIQ 379
++++F+ LE A ++
Sbjct: 1804 MEGAVKSKFKSTIAALEAKIAQLE 1827
>gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens]
Length = 971
Score = 59.3 bits (142), Expect = 1e-08
Identities = 94/413 (22%), Positives = 176/413 (42%), Gaps = 57/413 (13%)
Query: 2 EGERRAYSKEVH----QRINKQLEEIRR-----LEEVRGDLQVQISAAQNQVKRLRDSQR 52
+G+ +A +E+H + +NK LEE+R +E+ G L S + ++ L+ SQ
Sbjct: 94 KGQEKA--EELHRMEVESLNKMLEELRLERKKLIEDYEGKLNKAQSFYERELDTLKRSQL 151
Query: 53 LENMDRLLKGRAQVQAEI-EELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKI 111
L+ + +A++ +E Q Q L K I + +T + G +LD+ K+
Sbjct: 152 FTAES--LQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEA---GSLLDKCQKL 206
Query: 112 RRRIRILENQLDRVTCHFDNQLVRNAAL----REELDLLRIDRNRYLNVDRKLKKEIHHL 167
+ + I EN + + D+ AL +E L R R L + H+
Sbjct: 207 QTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHI 266
Query: 168 HHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVL----QRQILHLE-- 221
L +T + + + E K+++ + E+E A + Q L ++QIL LE
Sbjct: 267 GMLQATQMTQEVTIKDLESE-KSRVNERLSQLEEERAFLRSKTQSLDEEQKQQILELEKK 325
Query: 222 --------QLHHFLKLKNNDRQPDPDVLEKREKQAGEVAEGVWK-------------TSQ 260
Q ++ +LKN + + +V + E + + E WK +
Sbjct: 326 VNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDK 385
Query: 261 ERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKE 320
++L + E+ NK +L E D + L Q E+E + +N N E+ H+Q+ +++
Sbjct: 386 KKLQMDLEEQHNK-DKLNLEEDKNQLQQ---ELENLKEVLEDKLNTANQEIGHLQDMVRK 441
Query: 321 MQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEK 373
++ L SA LQ+ Q++ LQ +D + + +V G+LE+
Sbjct: 442 SEQGLGSAEGLIAS---LQDSQER-LQNELDLTKDSLKETKDALLNVEGELEQ 490
Score = 37.0 bits (84), Expect = 0.059
Identities = 53/240 (22%), Positives = 98/240 (40%), Gaps = 45/240 (18%)
Query: 4 ERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGR 63
E+ A +++ L +I L++ +L++Q+S +Q +++L+ E R
Sbjct: 558 EKNAARDSWQKKVEDLLNQISLLKQ---NLEIQLSQSQTSLQQLQAQFTQE--------R 606
Query: 64 AQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLD 123
++ E+EEL+EQ + K ++E F + + + R LEN L
Sbjct: 607 QRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEK------------EKEQRALENHLQ 654
Query: 124 RVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDR------------KLKKEIHHLHHLV 171
+ H A RE ++ RI+ + L R L+ E++H H
Sbjct: 655 QK--HSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAMLASLRSELNHQHAAA 712
Query: 172 STLILSSTSAYAVREEAKAKMGLLR--ERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKL 229
L+ + +E A AKM L R + + ++ + LQ ++ H E HH +L
Sbjct: 713 IDLLRHNHH----QELAAAKMELERSIDISRRQSKEHICRITDLQEELRHRE--HHISEL 766
Score = 36.2 bits (82), Expect = 0.10
Identities = 65/383 (16%), Positives = 164/383 (42%), Gaps = 35/383 (9%)
Query: 10 KEV-HQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQ-RLEN------------ 55
KEV ++N +EI L+++ + + +A+ + L+DSQ RL+N
Sbjct: 418 KEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKET 477
Query: 56 MDRLLKGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRI 115
D LL +++ E ++ E+T A K+ ++ + H ++ + + K+R +
Sbjct: 478 KDALLNVEGELEQERQQ-HEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLREEL 536
Query: 116 RILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNV-DRKLKKEIHHLHHLVSTL 174
R L+++ D + +A+ + L L ++N + +K++ ++ + L L
Sbjct: 537 R-LQHEED-----------KKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQNL 584
Query: 175 ILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQI--LHLEQLHHFLKLKNN 232
+ + + ++ +A+ R+R +E + E + Q + + H+ + K
Sbjct: 585 EIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEK 644
Query: 233 DRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLE 292
+++ + L+++ + + + S E + E L L + + +L E
Sbjct: 645 EQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAMLASLRSE 704
Query: 293 IEERNFAEFNFI-NEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKV--LQQR 349
+ ++ A + + + + EL + E++ + +S R SK+ + + Q+++ +
Sbjct: 705 LNHQHAAAIDLLRHNHHQELAAAKMELERSID--ISRRQSKEHICRITDLQEELRHREHH 762
Query: 350 MDKVHSEAERLEARFQDVRGQLE 372
+ ++ E + L + +LE
Sbjct: 763 ISELDKEVQHLHENISALTKELE 785
Score = 31.2 bits (69), Expect = 3.2
Identities = 35/164 (21%), Positives = 75/164 (45%), Gaps = 11/164 (6%)
Query: 1 MEGERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLL 60
+E E +A + +N Q ++ +R + +++AA+ +++R D R ++ + +
Sbjct: 690 LEDEGKAMLASLRSELNHQ--HAAAIDLLRHNHHQELAAAKMELERSIDISRRQSKEHIC 747
Query: 61 KGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILEN 120
+ I +LQE+ R + I E + + +N+ + L+ K K RIR N
Sbjct: 748 R--------ITDLQEELRHREHHISELDKEVQHLHENISALTKELEFKGKEILRIRSESN 799
Query: 121 QLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEI 164
Q R+ + L+R + E++ ++ + D+ +KK I
Sbjct: 800 QQIRLEEMEEKYLMRESK-PEDIQMITELKAMLTERDQIIKKLI 842
Score = 30.4 bits (67), Expect = 5.5
Identities = 53/238 (22%), Positives = 105/238 (44%), Gaps = 51/238 (21%)
Query: 4 ERRAYSKEVHQRINKQLEEIRRLEE--VRGDLQVQISAAQNQVKRLRDSQRLENMDRLLK 61
+R KE H + +EE + E+ + LQ + SA +++ L+D+ R E+M+
Sbjct: 622 QRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSA---ELQSLKDAHR-ESMEGF-- 675
Query: 62 GRAQVQAEIE----ELQEQTRALDKQIQEWETR-------IFTHSKNVRSPGFILDQKVK 110
R +++ E++ EL+++ +A+ ++ + H+ + + K++
Sbjct: 676 -RIEMEQELQTLRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQE----LAAAKME 730
Query: 111 IRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHL 170
+ R I I Q C + L+EEL R+R ++ +L KE+ HLH
Sbjct: 731 LERSIDISRRQSKEHICRITD-------LQEEL------RHREHHIS-ELDKEVQHLHEN 776
Query: 171 VSTLI------------LSSTSAYAVREEAKAKMGLLRE-RAEKEEAQSEMEAQVLQR 215
+S L + S S +R E + L+RE + E + +E++A + +R
Sbjct: 777 ISALTKELEFKGKEILRIRSESNQQIRLEEMEEKYLMRESKPEDIQMITELKAMLTER 834
>gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]
Length = 1140
Score = 59.3 bits (142), Expect = 1e-08
Identities = 94/413 (22%), Positives = 176/413 (42%), Gaps = 57/413 (13%)
Query: 2 EGERRAYSKEVH----QRINKQLEEIRR-----LEEVRGDLQVQISAAQNQVKRLRDSQR 52
+G+ +A +E+H + +NK LEE+R +E+ G L S + ++ L+ SQ
Sbjct: 214 KGQEKA--EELHRMEVESLNKMLEELRLERKKLIEDYEGKLNKAQSFYERELDTLKRSQL 271
Query: 53 LENMDRLLKGRAQVQAEI-EELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKI 111
L+ + +A++ +E Q Q L K I + +T + G +LD+ K+
Sbjct: 272 FTAES--LQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEA---GSLLDKCQKL 326
Query: 112 RRRIRILENQLDRVTCHFDNQLVRNAAL----REELDLLRIDRNRYLNVDRKLKKEIHHL 167
+ + I EN + + D+ AL +E L R R L + H+
Sbjct: 327 QTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHI 386
Query: 168 HHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVL----QRQILHLE-- 221
L +T + + + E K+++ + E+E A + Q L ++QIL LE
Sbjct: 387 GMLQATQMTQEVTIKDLESE-KSRVNERLSQLEEERAFLRSKTQSLDEEQKQQILELEKK 445
Query: 222 --------QLHHFLKLKNNDRQPDPDVLEKREKQAGEVAEGVWK-------------TSQ 260
Q ++ +LKN + + +V + E + + E WK +
Sbjct: 446 VNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDK 505
Query: 261 ERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKE 320
++L + E+ NK +L E D + L Q E+E + +N N E+ H+Q+ +++
Sbjct: 506 KKLQMDLEEQHNK-DKLNLEEDKNQLQQ---ELENLKEVLEDKLNTANQEIGHLQDMVRK 561
Query: 321 MQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEK 373
++ L SA LQ+ Q++ LQ +D + + +V G+LE+
Sbjct: 562 SEQGLGSAEGLIAS---LQDSQER-LQNELDLTKDSLKETKDALLNVEGELEQ 610
Score = 50.1 bits (118), Expect = 7e-06
Identities = 75/354 (21%), Positives = 147/354 (41%), Gaps = 53/354 (14%)
Query: 4 ERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGR 63
E+ A +++ L +I L++ +L++Q+S +Q +++L+ E R
Sbjct: 678 EKNAARDSWQKKVEDLLNQISLLKQ---NLEIQLSQSQTSLQQLQAQFTQE--------R 726
Query: 64 AQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLD 123
++ E+EEL+EQ + K ++E F + + + R LEN L
Sbjct: 727 QRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEK------------EKEQRALENHLQ 774
Query: 124 RVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDR------------KLKKEIHHLHHLV 171
+ H A RE ++ RI+ + L R L+ E++H H
Sbjct: 775 QK--HSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAMLASLRSELNHQHAAA 832
Query: 172 STLILSSTSAYAVREEAKAKMGLLR--ERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKL 229
L+ + +E A AKM L R + + ++ + LQ ++ H E HH +L
Sbjct: 833 IDLLRHNHH----QELAAAKMELERSIDISRRQSKEHICRITDLQEELRHRE--HHISEL 886
Query: 230 KNNDRQPDPDV--LEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLV 287
+ ++ L K + G+ + S +++ L +D +L E + D++
Sbjct: 887 DKEVQHLHENISALTKELEFKGKEILRIRSESNQQIRLHEQDLNKRL-----EKELDVMT 941
Query: 288 QKYLEIEERNFAEFNFINEQNLELE-HVQEEIKEMQEALVSARASKDDQHLLQE 340
+L + A+FN NE E+ +Q ++EM+E + + +D ++ E
Sbjct: 942 ADHLREKNIMRADFNKTNELLKEINAALQVSLEEMEEKYLMRESKPEDIQMITE 995
Score = 41.2 bits (95), Expect = 0.003
Identities = 98/544 (18%), Positives = 221/544 (40%), Gaps = 102/544 (18%)
Query: 1 MEGERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLL 60
+ G YS+E+H +++K+ I +L +V L + ++ ++ L+D+
Sbjct: 29 LAGHSMDYSQEMHLKMSKK---IAQLTKVIYALNTKNDEHESAIQALKDAH--------- 76
Query: 61 KGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILEN 120
+ EI+++ +TR ++I ++++++ +++ +RR+I++LE+
Sbjct: 77 ------EEEIQQILAETR---EKILQYKSKV--------------TEELDLRRKIQVLES 113
Query: 121 QLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTS 180
L+ D+ ++ AL E + ++ D +L E H+ +V+ S
Sbjct: 114 SLE------DHIKMKQQALTE------FEAYKHRVEDMQLCAEAQHVQRIVTM----SRE 157
Query: 181 AYAVREEAKAKM---GLLRERAEKEEAQSEMEAQVLQR----QILHLEQLHHFLKLKNND 233
+R + + K+ G L+ + EK++ + + Q R ++L +Q H N
Sbjct: 158 VEEIRRKFEEKLRSFGQLQVQFEKDKRLALEDLQAAHRREIQELLKSQQDH---SASVNK 214
Query: 234 RQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLEI 293
Q + L + E ++ + +++L+ YE LNK +Q E + D L + L
Sbjct: 215 GQEKAEELHRMEVESLNKMLEELRLERKKLIEDYEGKLNK-AQSFYERELDTLKRSQLFT 273
Query: 294 EERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQ---QQKVLQQRM 350
E S +ASK+ + L+++ Q+ +L++ +
Sbjct: 274 AE-------------------------------SLQASKEKEADLRKEFQGQEAILRKTI 302
Query: 351 DKVHSEAERLEARFQDVRGQLEKLKADIQLLFTKAHCDSSMIDDLLGVKTSMGDRDMGLF 410
K+ +E + ++ + + +KL+ + + +DD + ++ + +
Sbjct: 303 GKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVE 362
Query: 411 LSLIEKRLVELLTVQA--FLHAQSFTSLADAALLVLGQSLEDLPKKMAPL-QPPDTLEDP 467
L R E L QA + S + A + +++DL + + + + LE+
Sbjct: 363 SELAAAR--ERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEEE 420
Query: 468 PGFEASDDYPMSREELLSQVEKLVELQEQAEAQRQKDLAAAAAKLDGTLSVDLASTQRAG 527
F S + EE Q+ +L + +A+ +Q+ L L ++ A
Sbjct: 421 RAFLRSKTQSLD-EEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAH 479
Query: 528 SSTV 531
S T+
Sbjct: 480 SKTL 483
Score = 40.0 bits (92), Expect = 0.007
Identities = 44/215 (20%), Positives = 98/215 (45%), Gaps = 21/215 (9%)
Query: 1 MEGERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLL 60
+E E +A + +N Q ++ +R + +++AA+ +++R D R ++ + +
Sbjct: 810 LEDEGKAMLASLRSELNHQ--HAAAIDLLRHNHHQELAAAKMELERSIDISRRQSKEHIC 867
Query: 61 KGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILEN 120
+ I +LQE+ R + I E + + +N+ + L+ K K RIR N
Sbjct: 868 R--------ITDLQEELRHREHHISELDKEVQHLHENISALTKELEFKGKEILRIRSESN 919
Query: 121 QLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTS 180
Q R+ ++ N L +ELD++ D R N+ ++ + + + L+ + + +
Sbjct: 920 QQIRL-----HEQDLNKRLEKELDVMTADHLREKNI---MRADFNKTNELLKEI---NAA 968
Query: 181 AYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQR 215
EE + K + + E + +E++A + +R
Sbjct: 969 LQVSLEEMEEKYLMRESKPEDIQMITELKAMLTER 1003
Score = 36.2 bits (82), Expect = 0.10
Identities = 65/383 (16%), Positives = 164/383 (42%), Gaps = 35/383 (9%)
Query: 10 KEV-HQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQ-RLEN------------ 55
KEV ++N +EI L+++ + + +A+ + L+DSQ RL+N
Sbjct: 538 KEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKET 597
Query: 56 MDRLLKGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRI 115
D LL +++ E ++ E+T A K+ ++ + H ++ + + K+R +
Sbjct: 598 KDALLNVEGELEQERQQ-HEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLREEL 656
Query: 116 RILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNV-DRKLKKEIHHLHHLVSTL 174
R L+++ D + +A+ + L L ++N + +K++ ++ + L L
Sbjct: 657 R-LQHEED-----------KKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQNL 704
Query: 175 ILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQI--LHLEQLHHFLKLKNN 232
+ + + ++ +A+ R+R +E + E + Q + + H+ + K
Sbjct: 705 EIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEK 764
Query: 233 DRQPDPDVLEKREKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLE 292
+++ + L+++ + + + S E + E L L + + +L E
Sbjct: 765 EQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAMLASLRSE 824
Query: 293 IEERNFAEFNFI-NEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKV--LQQR 349
+ ++ A + + + + EL + E++ + +S R SK+ + + Q+++ +
Sbjct: 825 LNHQHAAAIDLLRHNHHQELAAAKMELERSID--ISRRQSKEHICRITDLQEELRHREHH 882
Query: 350 MDKVHSEAERLEARFQDVRGQLE 372
+ ++ E + L + +LE
Sbjct: 883 ISELDKEVQHLHENISALTKELE 905
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 58.5 bits (140), Expect = 2e-08
Identities = 95/430 (22%), Positives = 182/430 (42%), Gaps = 84/430 (19%)
Query: 2 EGERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDS----------- 50
E ERR +EV I K+ E E + DLQ + A +N+V+ L
Sbjct: 492 EAERRW--EEVQSYIRKRTAEH---EAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQL 546
Query: 51 -----QRLENMDRLLKGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFIL 105
Q +E+ + + +Q +++++ EQ AL QIQ++ ++I +
Sbjct: 547 EQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTS--------- 597
Query: 106 DQKVKIRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIH 165
+L +L +V D Q+ ++ D L +R+R + + +LK +I
Sbjct: 598 ---------ASVLAEELHKVIAEKDKQI------KQTEDSLASERDRLTSKEEELK-DIQ 641
Query: 166 HLHHLVSTLI-----LSSTSAYAVREEAKA---------KMGLLRERAEKEEAQSEMEAQ 211
+++ L+ + L++ A A E K K+ LL E+ + E + E +
Sbjct: 642 NMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFK 701
Query: 212 VLQRQILHLEQLHHFLKLKNNDRQPDPDVLEKREKQAGEVAEGVWKTSQERL------VL 265
+L Q L+ L+ ++ QP+ DV+E+ EK E E + KT +E L V
Sbjct: 702 ILNDQNKALKSEVQKLQTLVSE-QPNKDVVEQMEKCIQEKDEKL-KTVEELLETGLIQVA 759
Query: 266 CYEDALNKLSQLMGESDPDLLVQKYLEIEERNFAEF-----NFINEQNLELEHVQEEI-- 318
E+ LN + ++ K + ++ +FA I+E++ +++ V+E +
Sbjct: 760 TKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEA 819
Query: 319 -------KEMQEALVSARASKDDQHLLQ--EQQQKVLQQRMDKVHSEAERLEARFQDVRG 369
KE L ++ Q+LL+ E+Q ++ +++ + QD++
Sbjct: 820 ELLKVANKEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQE 879
Query: 370 QLEKLKADIQ 379
+ E LKA +Q
Sbjct: 880 ENESLKAHVQ 889
Score = 50.4 bits (119), Expect = 5e-06
Identities = 88/442 (19%), Positives = 198/442 (44%), Gaps = 52/442 (11%)
Query: 1 MEGERRAYSKEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLL 60
+E E + ++H + + + ++VR ++ +I+ + + LRD+ + N L
Sbjct: 383 LEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDA--VSNTTNQL 440
Query: 61 KGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILEN 120
+ + AE+ +L++ L ++ E ++ ++ +++ +++ E
Sbjct: 441 ESKQ--SAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAE---QAATQLKVQLQEAER 495
Query: 121 QLDRVTCHFDNQLVRNAALREELDLLRIDR-NRYLNVDRKLKKEIHHLHHLVSTLI-LSS 178
+ + V + + + A +++L + + N ++ KL + L L+ L
Sbjct: 496 RWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLME 555
Query: 179 TSAYAVREEAKAKM---GLLRE----RAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKN 231
+ V +E +M +L + +A+ ++ S++ AQ + E+LH + K+
Sbjct: 556 SEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVL--AEELHKVIAEKD 613
Query: 232 ND-RQPDPDVLEKREKQAGEVAE--------GVWKTSQERL-VLCYEDA-----LNKLSQ 276
+Q + + +R++ + E + K ++L L E A L K+ Q
Sbjct: 614 KQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQ 673
Query: 277 LMGESDPDL-LVQKYLEIEERN-FAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDD 334
+ D + L+++ L+ E N EF +N+QN L + E++++Q LVS + +KD
Sbjct: 674 SVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKAL---KSEVQKLQ-TLVSEQPNKD- 728
Query: 335 QHLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEKLKADIQLLFTKAHCDSSMIDD 394
+ EQ +K +Q++ +K+ + E LE V + E+L A + T+ +SS+ +
Sbjct: 729 ---VVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNA----IRTE---NSSLTKE 778
Query: 395 LLGVKTSMGDRDMGLFLSLIEK 416
+ +K D+ F SL+E+
Sbjct: 779 VQDLKAKQNDQVS--FASLVEE 798
Score = 38.9 bits (89), Expect = 0.016
Identities = 80/402 (19%), Positives = 180/402 (44%), Gaps = 60/402 (14%)
Query: 10 KEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVK--RLRDSQRLENMDRLLKGRAQ-- 65
+E+ + I+++ +I+ +EE+ L+ ++ N+ K +L + +++ + LLKG+ +
Sbjct: 797 EELKKVIHEKDGKIKSVEEL---LEAELLKVANKEKTVQLSITSKVQELQNLLKGKEEQM 853
Query: 66 --VQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLD 123
++A +EE ++ K +Q+ + + +V+ + +K E +L+
Sbjct: 854 NTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQE---VAQHNLKEASSASQFE-ELE 909
Query: 124 RVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLI-------L 176
V +N+L R A+ +E R L+ +L +++ + L + I
Sbjct: 910 IVLKEKENELKRLEAMLKE-------RESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNY 962
Query: 177 SSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNND-RQ 235
S++ EE LL+ +E+E+ E L ++ L+ + KNND R+
Sbjct: 963 QQASSFPPHEE------LLKVISEREK-----EISGLWNELDSLKDAVEHQRKKNNDLRE 1011
Query: 236 PDPDVLEKREKQAGEVAEGVWKTSQER------LVLCYEDALNKLSQLMGESDPDLLVQK 289
+ + +E + + V KTS+ER + L ++ L KL + +L +
Sbjct: 1012 KNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPS-NLSYGE 1070
Query: 290 YLEIEERNFAEFNFINEQNLELEHVQEEIKEMQE--ALVSARASK------DDQHLLQEQ 341
+L E+ E + E++ ++ ++KE E L+ K + + +LQ+
Sbjct: 1071 WLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKL 1130
Query: 342 QQKVLQQ------RMDKVHSEAERLEARFQDVRGQLEKLKAD 377
Q+ V Q+ ++D+ H +++++ F +LE+L+++
Sbjct: 1131 QRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSE 1172
Score = 33.5 bits (75), Expect = 0.65
Identities = 48/240 (20%), Positives = 96/240 (40%), Gaps = 42/240 (17%)
Query: 171 VSTLILSST--SAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLK 228
V TL++ S A + +E K + G +++A ++ ++E + ++H +
Sbjct: 181 VETLMVPSKRQEALPLHQETKQESGSGKKKASSKKQKTENV--FVDEPLIHATT--YIPL 236
Query: 229 LKNNDRQPDPDVLEKREKQAGEVAEGVWK---------TSQERLVLCYEDALNKLSQLMG 279
+ N D P D E + + EG+ K T +E + ++D L L +M
Sbjct: 237 MDNADSSPVVDKREVIDLLKPDQVEGIQKSGTKKLKTETDKENAEVKFKDFLLSLKTMMF 296
Query: 280 ESDPDLLVQKYLEIEE---RNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKD--- 333
D L V L+ + ++ + + E + +QE+ K + A A+KD
Sbjct: 297 SEDEALCVVDLLKEKSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCK 356
Query: 334 ---------------------DQHLLQEQQQKVLQQRMDKVHSEAERLEARFQDVRGQLE 372
D+ E++ V Q ++ + E ++++ +FQ VR Q+E
Sbjct: 357 QLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQME 416
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 58.5 bits (140), Expect = 2e-08
Identities = 82/397 (20%), Positives = 163/397 (41%), Gaps = 39/397 (9%)
Query: 10 KEVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKGRAQVQAE 69
+E ++ K ++ LE D Q + Q +L S R+ ++ + Q E
Sbjct: 1297 EEAEKKGIKFAKDAASLESQLQDTQELLQEETRQ--KLNLSSRIRQLEEEKNSLQEQQEE 1354
Query: 70 IEE----LQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLDRV 125
EE L++Q AL Q+ + + ++ + S + + K K+ + L +L+
Sbjct: 1355 EEEARKNLEKQVLALQSQLADTKKKVDDDLGTIES---LEEAKKKLLKDAEALSQRLEEK 1411
Query: 126 TCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSAYAVR 185
+D L++ELD L +D + V L+K+ L+ A
Sbjct: 1412 ALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLL-----------AEE 1460
Query: 186 EEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPDVLEKRE 245
+ A+ R+RAE E + E +A L R + + + +N + D + L +
Sbjct: 1461 KSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSK 1520
Query: 246 KQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLEI------------ 293
G+ + K S+ L E+ +L +L E + LE+
Sbjct: 1521 DDVGKNVHELEK-SKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERD 1579
Query: 294 ----EERNFAEFNFINEQNLELE-HVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQ 348
+E+N + + +Q ELE +++E K+ A+ S + + D L+ Q + +
Sbjct: 1580 LQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKA 1639
Query: 349 RMDKVHSEAERLEARFQDVRGQLEKLKADIQLLFTKA 385
R D+V + +L+A+ +D + +LE+ +A +F ++
Sbjct: 1640 R-DEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQS 1675
Score = 54.3 bits (129), Expect = 4e-07
Identities = 91/428 (21%), Positives = 182/428 (42%), Gaps = 71/428 (16%)
Query: 11 EVHQRINKQLEEIRRLEEVRGDLQVQISAAQNQVKRLRDS-QRLENMDRLLKGR------ 63
E ++ ++ E+ + L ++R +V IS + ++K+ + Q LE R L G
Sbjct: 1010 ECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQD 1069
Query: 64 --AQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQ 121
A++QA+I+EL+ Q ++++Q R + + K + +R L+ Q
Sbjct: 1070 QIAELQAQIDELKLQLAKKEEELQGALARGDDETLH----------KNNALKVVRELQAQ 1119
Query: 122 LDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSA 181
+ A L+E+ + + RN+ R L +E+ L + + ++ +
Sbjct: 1120 I--------------AELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQ 1165
Query: 182 YAVREEAKAKMGLLRERAEKEEAQSEMEAQ-VLQRQILHLEQLHHFLK--------LKNN 232
+R + + ++ L++ E+E E + Q + QR LE+L L+ L+ N
Sbjct: 1166 QELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKN 1225
Query: 233 DRQPDPDVLE-----------------KREKQAGEVAEGVWKTSQ-ERLVLCYEDALNKL 274
+ + D E KR+K +V E K S+ +RL + + K
Sbjct: 1226 KQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRV---ELAEKA 1282
Query: 275 SQLMGESDPDLLVQKYLEIEERNFAEFNFINEQNLE--LEHVQEEIKEMQEALVSARASK 332
S+L E D + + E + FA+ E L+ E +QEE ++ R +
Sbjct: 1283 SKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLE 1342
Query: 333 DDQHLLQEQQQ------KVLQQRMDKVHSEAERLEARFQDVRGQLEKLKADIQLLFTKAH 386
++++ LQEQQ+ K L++++ + S+ + + D G +E L+ + L A
Sbjct: 1343 EEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAE 1402
Query: 387 CDSSMIDD 394
S +++
Sbjct: 1403 ALSQRLEE 1410
Score = 35.0 bits (79), Expect = 0.22
Identities = 48/202 (23%), Positives = 87/202 (43%), Gaps = 34/202 (16%)
Query: 193 GLLRERAEKEEAQSEMEAQVLQRQILHLEQLHH------FLKLK---NNDRQPDPDVLEK 243
G L +A ++ Q +VLQR +L H F K+K RQ + L+
Sbjct: 799 GYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEE--LQA 856
Query: 244 REKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEERNFAEFNF 303
++++ +V E K E E+ K QL+ E + ++ + L+ E FAE
Sbjct: 857 KDEELLKVKEKQTKVEGE-----LEEMERKHQQLLEEKN---ILAEQLQAETELFAE--- 905
Query: 304 INEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERLEAR 363
E L ++E++E+ L S +E++ ++LQ K+ + + LE +
Sbjct: 906 AEEMRARLAAKKQELEEILHDLESRVEE-------EEERNQILQNEKKKMQAHIQDLEEQ 958
Query: 364 FQDVRG-----QLEKLKADIQL 380
+ G QLEK+ A+ ++
Sbjct: 959 LDEEEGARQKLQLEKVTAEAKI 980
Score = 33.1 bits (74), Expect = 0.85
Identities = 68/384 (17%), Positives = 155/384 (40%), Gaps = 66/384 (17%)
Query: 169 HLVSTLILSSTSAYAVREEAKAKMGL-----------LRERAEKEEAQSEMEAQVLQRQI 217
++++ + + T +A EE +A++ L R E+EE ++++ ++
Sbjct: 890 NILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQ 949
Query: 218 LHLEQLHHFLKLKNNDRQP---------------DPDVLEKREKQAGEVAEGVWKTSQER 262
H++ L L + RQ + ++L ++ + + E K ++R
Sbjct: 950 AHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEK--KLMEDR 1007
Query: 263 LVLC------YEDALNKLSQLMGESDPDLL-VQKYLEIEERNFAEF-------------- 301
+ C E+ L+++ + + + +++ L+ EE+ E
Sbjct: 1008 IAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDL 1067
Query: 302 -NFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAERL 360
+ I E +++ ++ ++ + +E L A A DD+ L + KV+++ ++ E
Sbjct: 1068 QDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDF 1127
Query: 361 EARFQDVRGQLEKLKADIQLLFTKAHCDSSMIDDLLGVKTSMGDRDMGLFLSLIE-KRLV 419
E+ + R + EK K D L + + ++D L + + + E K+ +
Sbjct: 1128 ESE-KASRNKAEKQKRD---LSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKAL 1183
Query: 420 ELLTVQAFLHAQSFTSLADAALLVLGQSLEDLPKKMAPLQPPDTLEDPPGFEASDDYPMS 479
E T Q AL L + LE + A L+ ++ G E +
Sbjct: 1184 EEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLE-----KNKQGLETDN----- 1233
Query: 480 REELLSQVEKLVELQEQAEAQRQK 503
+EL +V+ L +++ ++E +R+K
Sbjct: 1234 -KELACEVKVLQQVKAESEHKRKK 1256
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 58.2 bits (139), Expect = 2e-08
Identities = 82/387 (21%), Positives = 164/387 (42%), Gaps = 41/387 (10%)
Query: 23 IRRLEEVRGDLQVQISAAQNQVKRLRDSQRLENMDRLLKG--RAQVQAEIEELQEQTRAL 80
I L + + DLQ + A + Q LR +R LKG + +V + +E+ +
Sbjct: 729 IEELLQAKQDLQDLLIAKEEQEDLLRKRERELTA---LKGALKEEVSSHDQEMDKLKEQY 785
Query: 81 DKQIQEWETRIFTHSKNV-----RSPGFILDQKVKIRRRIRILENQLDRVTCHFDNQLVR 135
D ++Q + +KNV RS DQ R+++L+ + +++ + R
Sbjct: 786 DAELQALRESVEEATKNVEVLASRSNTSEQDQ-AGTEMRVKLLQEENEKLQGRSEELERR 844
Query: 136 NAALREELDLLRIDRNRYLNVDRKLKKEIHHLHHLVSTLILSSTSAYAVRE----EAKAK 191
A L+ +++ L+ D + +K + EI L + A + R E +A
Sbjct: 845 VAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAA 904
Query: 192 MGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHHFLKLKNNDRQPDPDVLEKREKQAGEV 251
G L + ++++ SE L+ + EQL N+R +EK +K+ ++
Sbjct: 905 QGNLSQTTQEQKQLSEK----LKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADI 960
Query: 252 AEGVWKTSQERLVLCYEDALNKLSQLMGESDPDLLVQKYLEIEERNFA------EFNFIN 305
E +TS L ++ K + + E L +K LE E+ E +
Sbjct: 961 VEAS-RTSTLELQNQLDEYKEKNRRELAEMQRQ-LKEKTLEAEKSRLTAMKMQDEMRLME 1018
Query: 306 EQNLELEHVQEE-----------IKEMQEALVSARASKDDQ-HLLQEQQQKV--LQQRMD 351
E+ + + Q+E +K+++ L + KDD+ L+++ + KV L+ ++
Sbjct: 1019 EELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELE 1078
Query: 352 KVHSEAERLEARFQDVRGQLEKLKADI 378
+ + ++ L R R Q+E+L+ ++
Sbjct: 1079 EERNNSDLLSERISRSREQMEQLRNEL 1105
Score = 54.7 bits (130), Expect = 3e-07
Identities = 83/429 (19%), Positives = 174/429 (40%), Gaps = 67/429 (15%)
Query: 14 QRINKQLEEIRRLEEV--------------RGDLQVQISAAQNQVKRLRDSQRL--ENMD 57
+ + K EIR+LEE R L+ ++ AAQ + + Q+ E +
Sbjct: 864 ETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLK 923
Query: 58 RLLKGRAQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFIL-----DQKVKIR 112
+ + Q++ E++ + L K I++ + + + R+ L + K K R
Sbjct: 924 EESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNR 983
Query: 113 RRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRY-------LNVDRKLKKEIH 165
R + ++ QL T + + +++E+ L+ + Y L + L++ +
Sbjct: 984 RELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLK 1043
Query: 166 HLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQLHH 225
L + + + ++ + K+ L E+E S++ ++ + R +EQL +
Sbjct: 1044 DLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRN 1103
Query: 226 FL---KLKNNDRQPDPDVLEKREKQAGEVA---EGVWKTSQERLVLCYEDALNKLSQLMG 279
L + D + D LE++ K EG +++S+E LV+ E + +L
Sbjct: 1104 ELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAEL----- 1158
Query: 280 ESDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQ 339
+ LE EER+ A N + ++ ++KE+ + S DQ
Sbjct: 1159 --------EDRLESEERDRANLQLSNRR------LERKVKELVMQVDDEHLSLTDQKDQL 1204
Query: 340 EQQQKVLQQRMDKVHSEAERLEA--------------RFQDVRGQLEKLKADIQLLFTKA 385
+ K +++++++ E +RLE+ + ++GQL +K D++L +
Sbjct: 1205 SLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPS 1264
Query: 386 HCDSSMIDD 394
M DD
Sbjct: 1265 KVLDDMDDD 1273
Score = 47.0 bits (110), Expect = 6e-05
Identities = 65/278 (23%), Positives = 114/278 (41%), Gaps = 35/278 (12%)
Query: 104 ILDQKVKIRRRIRILENQLDRVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRKLKKE 163
+L+QK K+ + L+ QL + N +R L+ LR N + + L++
Sbjct: 612 LLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQR 671
Query: 164 IHHLHHLVSTLILSSTSAYAVREEAKAKMGLLRERAEKEEAQSEMEAQVLQRQILHLEQL 223
+ + E K L + + E+E+ Q+E+ LQ Q L ++
Sbjct: 672 LEE----------------SEGELRKNLEELFQVKMEREQHQTEIRD--LQDQ---LSEM 710
Query: 224 HHFLKLKNNDRQPDPDVLEKREKQAGEVAEG--VWKTSQERLVLCYEDALNKLSQLMGE- 280
H L + L + QA + + + K QE L+ E L L + E
Sbjct: 711 HDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEE 770
Query: 281 -SDPDLLVQKYLEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASKDDQHLLQ 339
S D Q+ +++E+ AE + E V+E K ++ + S+ DQ
Sbjct: 771 VSSHD---QEMDKLKEQYDAELQALRES------VEEATKNVEVLASRSNTSEQDQ-AGT 820
Query: 340 EQQQKVLQQRMDKVHSEAERLEARFQDVRGQLEKLKAD 377
E + K+LQ+ +K+ +E LE R ++ Q+E LK D
Sbjct: 821 EMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGD 858
Score = 37.0 bits (84), Expect = 0.059
Identities = 65/246 (26%), Positives = 104/246 (42%), Gaps = 41/246 (16%)
Query: 306 EQNLELE-HVQEEIKEMQEALVSARASKDDQHLLQEQQQKVLQQRMDKVHSEAER-LEAR 363
++ L+LE Q+ IKE +E + + QH + ++ LQQR+++ E + LE
Sbjct: 627 QRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEEL 686
Query: 364 FQDVRGQLEKLKADIQLLFTKAHCDSSMIDDLLGVKTSMGDRDMGLFL------------ 411
FQ V+ + E+ + +I+ L + S M D+L K S DR+ G +
Sbjct: 687 FQ-VKMEREQHQTEIRDLQDQL---SEMHDELDSAKRS-EDREKGALIEELLQAKQDLQD 741
Query: 412 ---------SLIEKRLVELLTVQAFL------HAQSFTSLA---DAALLVLGQSLEDLPK 453
L+ KR EL ++ L H Q L DA L L +S+E+ K
Sbjct: 742 LLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATK 801
Query: 454 KMAPL--QPPDTLEDPPGFEASDDYPMSREELLSQVEKLVELQEQAEAQRQ-KDLAAAAA 510
+ L + + +D G E E L + +E + A+ QRQ +DL A
Sbjct: 802 NVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELE-RRVAQLQRQIEDLKGDEA 860
Query: 511 KLDGTL 516
K TL
Sbjct: 861 KAKETL 866
>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
sapiens]
Length = 1591
Score = 57.4 bits (137), Expect = 4e-08
Identities = 99/443 (22%), Positives = 200/443 (45%), Gaps = 51/443 (11%)
Query: 10 KEVHQRINKQLEEIRRLEEVRGDLQVQI------SAAQNQVKRLRDSQRLENMDRLLKGR 63
KE+ Q LE++++L V D ++Q+ S Q+ +K L D+ ++ ++ K
Sbjct: 949 KELKQSREIVLEDLKKLH-VENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVM 1007
Query: 64 AQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLD 123
+ +EEL+++ + + QIQE +H++ I+ +K K + +++ + L
Sbjct: 1008 TDHRVSLEELKKENQQIINQIQE------SHAE-------IIQEKEKQLQELKLKVSDLS 1054
Query: 124 RVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRK--LKKEIHHLHHLVSTL---ILSS 178
C + +L A +E+ +L + K L++E +L +S L I +
Sbjct: 1055 DTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDN 1114
Query: 179 TSAYAV-REEAKAKMGLLRERAEKE-EAQSEMEAQVLQRQILHLEQLHH-FLKLKNNDRQ 235
Y V E + M + +++ E ++ E E+ +L+ ++ + LH+ +++ N ++
Sbjct: 1115 NENYQVGLAELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKE 1174
Query: 236 PDPDVLEK--REKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLM---GESDPDLLVQKY 290
++ K E A E + T QE L K Q + E D + L+QK
Sbjct: 1175 QIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKL 1234
Query: 291 LEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASK--------DDQHLLQEQQ 342
E++ A + E LE E V++E+ E + L + A D L+ E Q
Sbjct: 1235 --NCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQ 1292
Query: 343 QKVLQQR---MDKVHSEAERLEARFQDVRGQL-EKLKADIQLLFTKAHC-DSSMIDDLLG 397
+K+ +++ ++++ + +R Q+VR L + + + + T+ ++I+DL
Sbjct: 1293 EKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSD 1352
Query: 398 -VKTSM--GDRDMGLFLSLIEKR 417
+K++M +RD L SL E R
Sbjct: 1353 KLKSTMQQQERDKDLIESLSEDR 1375
>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
sapiens]
Length = 1594
Score = 57.4 bits (137), Expect = 4e-08
Identities = 99/443 (22%), Positives = 200/443 (45%), Gaps = 51/443 (11%)
Query: 10 KEVHQRINKQLEEIRRLEEVRGDLQVQI------SAAQNQVKRLRDSQRLENMDRLLKGR 63
KE+ Q LE++++L V D ++Q+ S Q+ +K L D+ ++ ++ K
Sbjct: 949 KELKQSREIVLEDLKKLH-VENDEKLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVM 1007
Query: 64 AQVQAEIEELQEQTRALDKQIQEWETRIFTHSKNVRSPGFILDQKVKIRRRIRILENQLD 123
+ +EEL+++ + + QIQE +H++ I+ +K K + +++ + L
Sbjct: 1008 TDHRVSLEELKKENQQIINQIQE------SHAE-------IIQEKEKQLQELKLKVSDLS 1054
Query: 124 RVTCHFDNQLVRNAALREELDLLRIDRNRYLNVDRK--LKKEIHHLHHLVSTL---ILSS 178
C + +L A +E+ +L + K L++E +L +S L I +
Sbjct: 1055 DTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDN 1114
Query: 179 TSAYAV-REEAKAKMGLLRERAEKE-EAQSEMEAQVLQRQILHLEQLHH-FLKLKNNDRQ 235
Y V E + M + +++ E ++ E E+ +L+ ++ + LH+ +++ N ++
Sbjct: 1115 NENYQVGLAELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKE 1174
Query: 236 PDPDVLEK--REKQAGEVAEGVWKTSQERLVLCYEDALNKLSQLM---GESDPDLLVQKY 290
++ K E A E + T QE L K Q + E D + L+QK
Sbjct: 1175 QIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQKL 1234
Query: 291 LEIEERNFAEFNFINEQNLELEHVQEEIKEMQEALVSARASK--------DDQHLLQEQQ 342
E++ A + E LE E V++E+ E + L + A D L+ E Q
Sbjct: 1235 --NCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQ 1292
Query: 343 QKVLQQR---MDKVHSEAERLEARFQDVRGQL-EKLKADIQLLFTKAHC-DSSMIDDLLG 397
+K+ +++ ++++ + +R Q+VR L + + + + T+ ++I+DL
Sbjct: 1293 EKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSD 1352
Query: 398 -VKTSM--GDRDMGLFLSLIEKR 417
+K++M +RD L SL E R
Sbjct: 1353 KLKSTMQQQERDKDLIESLSEDR 1375
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,184,199
Number of Sequences: 37866
Number of extensions: 1133609
Number of successful extensions: 11033
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 157
Number of HSP's successfully gapped in prelim test: 823
Number of HSP's that attempted gapping in prelim test: 6887
Number of HSP's gapped (non-prelim): 3313
length of query: 670
length of database: 18,247,518
effective HSP length: 109
effective length of query: 561
effective length of database: 14,120,124
effective search space: 7921389564
effective search space used: 7921389564
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.