Guide to the Human Genome
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Search of human proteins with 21536407

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]
         (497 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]            999   0.0  
gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]            961   0.0  
gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]            943   0.0  
gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]             891   0.0  
gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]            874   0.0  
gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]            858   0.0  
gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens]            857   0.0  
gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens]            853   0.0  
gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens]            849   0.0  
gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens]           725   0.0  
gi|21536423 amphiphysin isoform 2 [Homo sapiens]                      424   e-119
gi|4502081 amphiphysin isoform 1 [Homo sapiens]                       424   e-119
gi|49472835 bridging integrator 2 [Homo sapiens]                      314   1e-85
gi|8923904 bridging integrator 3 [Homo sapiens]                        57   4e-08
gi|39930351 dynamin binding protein [Homo sapiens]                     49   8e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni...    49   8e-06
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    48   2e-05
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    47   5e-05
gi|49640014 ubiquitin associated and SH3 domain containing, A sh...    46   7e-05
gi|9507221 ubiquitin associated and SH3 domain containing, A lon...    46   7e-05
gi|109689723 abl interactor 2 [Homo sapiens]                           45   2e-04
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ...    45   2e-04
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [...    45   2e-04
gi|115527120 nebulin [Homo sapiens]                                    44   3e-04
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    44   4e-04
gi|153792074 proline rich 12 [Homo sapiens]                            44   4e-04
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             43   6e-04
gi|194578923 sperm associated antigen 9 isoform 1 [Homo sapiens]       43   6e-04
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         43   6e-04
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]          43   8e-04

>gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]
          Length = 497

 Score =  999 bits (2584), Expect = 0.0
 Identities = 497/497 (100%), Positives = 497/497 (100%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
           KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300

Query: 301 EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS 360
           EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS
Sbjct: 301 EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS 360

Query: 361 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 420
           QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD
Sbjct: 361 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 420

Query: 421 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 480
           LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE
Sbjct: 421 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 480

Query: 481 LEKCRGVFPENFTERVP 497
           LEKCRGVFPENFTERVP
Sbjct: 481 LEKCRGVFPENFTERVP 497


>gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]
          Length = 482

 Score =  961 bits (2485), Expect = 0.0
 Identities = 482/497 (96%), Positives = 482/497 (96%), Gaps = 15/497 (3%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
           KQHGSNTFTVKAQP               SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQP---------------SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 285

Query: 301 EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS 360
           EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS
Sbjct: 286 EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS 345

Query: 361 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 420
           QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD
Sbjct: 346 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 405

Query: 421 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 480
           LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE
Sbjct: 406 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 465

Query: 481 LEKCRGVFPENFTERVP 497
           LEKCRGVFPENFTERVP
Sbjct: 466 LEKCRGVFPENFTERVP 482


>gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]
          Length = 518

 Score =  943 bits (2438), Expect = 0.0
 Identities = 482/533 (90%), Positives = 482/533 (90%), Gaps = 51/533 (9%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
           KQHGSNTFTVKAQP               SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQP---------------SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 285

Query: 301 EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS 360
           EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS
Sbjct: 286 EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS 345

Query: 361 ------------------------------------QPAEASEVAGGTQPAAGAQEPGET 384
                                               QPAEASEVAGGTQPAAGAQEPGET
Sbjct: 346 QPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET 405

Query: 385 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 444
           AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ
Sbjct: 406 AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 465

Query: 445 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 497
           LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 466 LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 518


>gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]
          Length = 454

 Score =  891 bits (2303), Expect = 0.0
 Identities = 454/497 (91%), Positives = 454/497 (91%), Gaps = 43/497 (8%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
           KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300

Query: 301 EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS 360
           EPAGGATPGATLPKSP                                           S
Sbjct: 301 EPAGGATPGATLPKSP-------------------------------------------S 317

Query: 361 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 420
           QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD
Sbjct: 318 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 377

Query: 421 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 480
           LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE
Sbjct: 378 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 437

Query: 481 LEKCRGVFPENFTERVP 497
           LEKCRGVFPENFTERVP
Sbjct: 438 LEKCRGVFPENFTERVP 454


>gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]
          Length = 475

 Score =  874 bits (2258), Expect = 0.0
 Identities = 447/497 (89%), Positives = 453/497 (91%), Gaps = 22/497 (4%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
           KQHGSNTFTVKAQP               SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQP---------------SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 285

Query: 301 EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS 360
           EPAGGATPGATLPKSPSQ     P   P    PS E    +    F  ++  + +   P+
Sbjct: 286 EPAGGATPGATLPKSPSQ-----PTESPAGSLPSGEPSAAE--GTFAVSWPSQTAEPGPA 338

Query: 361 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 420
           QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD
Sbjct: 339 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 398

Query: 421 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 480
           LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE
Sbjct: 399 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 458

Query: 481 LEKCRGVFPENFTERVP 497
           LEKCRGVFPENFTERVP
Sbjct: 459 LEKCRGVFPENFTERVP 475


>gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]
          Length = 506

 Score =  858 bits (2216), Expect = 0.0
 Identities = 447/528 (84%), Positives = 453/528 (85%), Gaps = 53/528 (10%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180

Query: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240

Query: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSKLFSRLRRKKN 269
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP               
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP--------------- 285

Query: 270 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPP 329
           SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ     P   P 
Sbjct: 286 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ-----PTESPA 340

Query: 330 KHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEA 389
              PS E    +    F  ++  + +   P+QPAEASEVAGGTQPAAGAQEPGETAASEA
Sbjct: 341 GSLPSGEPSAAE--GTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEA 398

Query: 390 ASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGD 449
           ASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGD
Sbjct: 399 ASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGD 458

Query: 450 VVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 497
           VVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Sbjct: 459 VVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP 506


>gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens]
          Length = 593

 Score =  857 bits (2213), Expect = 0.0
 Identities = 462/608 (75%), Positives = 466/608 (76%), Gaps = 126/608 (20%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180

Query: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240

Query: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSKLFSRLRRKKN 269
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP               
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP--------------- 285

Query: 270 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPP 329
           SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPP
Sbjct: 286 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPP 345

Query: 330 KHTPSKEVKQEQILSLFEDTFVPEISVTTPSQ---PAEASEVAG---------------- 370
           KHTPSKEVKQEQILSLFEDTFVPEISVTTPSQ   P   SE A                 
Sbjct: 346 KHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPV 405

Query: 371 ----------------GTQPAAGAQEPGETA------------------------ASEAA 390
                            T+  AG+   GE +                        ASE A
Sbjct: 406 KAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVA 465

Query: 391 SSSLPA---------------------VVVETFPATVNGTVEGGSGAGRLDLPPGFMFKV 429
             + PA                     VVVETFPATVNGTVEGGSGAGRLDLPPGFMFKV
Sbjct: 466 GGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKV 525

Query: 430 QAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFP 489
           QAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFP
Sbjct: 526 QAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFP 585

Query: 490 ENFTERVP 497
           ENFTERVP
Sbjct: 586 ENFTERVP 593


>gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens]
          Length = 439

 Score =  853 bits (2204), Expect = 0.0
 Identities = 439/497 (88%), Positives = 439/497 (88%), Gaps = 58/497 (11%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
           KQHGSNTFTVKAQP               SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP
Sbjct: 241 KQHGSNTFTVKAQP---------------SDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 285

Query: 301 EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS 360
           EPAGGATPGATLPKSP                                           S
Sbjct: 286 EPAGGATPGATLPKSP-------------------------------------------S 302

Query: 361 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 420
           QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD
Sbjct: 303 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 362

Query: 421 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 480
           LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE
Sbjct: 363 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 422

Query: 481 LEKCRGVFPENFTERVP 497
           LEKCRGVFPENFTERVP
Sbjct: 423 LEKCRGVFPENFTERVP 439


>gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens]
          Length = 550

 Score =  849 bits (2194), Expect = 0.0
 Identities = 453/565 (80%), Positives = 458/565 (81%), Gaps = 83/565 (14%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK------- 173
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAK       
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK 180

Query: 174 ------------------------AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 209
                                   AEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
Sbjct: 181 AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN 240

Query: 210 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSKLFSRLRRKKN 269
           TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP               
Sbjct: 241 TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP--------------- 285

Query: 270 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPV---- 325
           SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ     P     
Sbjct: 286 SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQFEAPGPFSEQA 345

Query: 326 --------PPPPKHTPSKEVK---QEQILSLFEDTFVPEISVTT---------------- 358
                   P PP  +P K      Q     L+E T  P  S+ +                
Sbjct: 346 SLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPS 405

Query: 359 ------PSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEG 412
                 P+QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEG
Sbjct: 406 QTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEG 465

Query: 413 GSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKE 472
           GSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKE
Sbjct: 466 GSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKE 525

Query: 473 SDWNQHKELEKCRGVFPENFTERVP 497
           SDWNQHKELEKCRGVFPENFTERVP
Sbjct: 526 SDWNQHKELEKCRGVFPENFTERVP 550


>gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens]
          Length = 409

 Score =  725 bits (1871), Expect = 0.0
 Identities = 385/497 (77%), Positives = 389/497 (78%), Gaps = 88/497 (17%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
Sbjct: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
Sbjct: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK
Sbjct: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE
Sbjct: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240

Query: 241 KQHGSNTFTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEP 300
           KQHGSNTFTVKAQP               SDNAPAKGNKS                    
Sbjct: 241 KQHGSNTFTVKAQP---------------SDNAPAKGNKS-------------------- 265

Query: 301 EPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPS 360
                                    P PP  +P+                 PEI V    
Sbjct: 266 -------------------------PSPPDGSPAA---------------TPEIRVNHEP 285

Query: 361 QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLD 420
           +PA             G   PG T     + SSLPAVVVETFPATVNGTVEGGSGAGRLD
Sbjct: 286 EPA-------------GGATPGATLPKSPSQSSLPAVVVETFPATVNGTVEGGSGAGRLD 332

Query: 421 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 480
           LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE
Sbjct: 333 LPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKE 392

Query: 481 LEKCRGVFPENFTERVP 497
           LEKCRGVFPENFTERVP
Sbjct: 393 LEKCRGVFPENFTERVP 409


>gi|21536423 amphiphysin isoform 2 [Homo sapiens]
          Length = 653

 Score =  424 bits (1091), Expect = e-119
 Identities = 216/354 (61%), Positives = 261/354 (73%), Gaps = 19/354 (5%)

Query: 9   VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
           +  G  A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q  EGTRLQ++LR Y
Sbjct: 4   IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63

Query: 69  LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
           LA++K M EAS KL E L EVYEPDW GR++   + E  D+LW D+HQKLVD +LLT+DT
Sbjct: 64  LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123

Query: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
           YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE  KAQKVFEE 
Sbjct: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183

Query: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
           NVDLQEELPSLW+ RVGFYVNTF++++ LE  FHKE++ L   L +V+  L  QH    F
Sbjct: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243

Query: 249 TVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGAT 307
           T++  P               SD+ P +  K+PSPP + SP  +P    NH   P   A+
Sbjct: 244 TIQGAP---------------SDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---AS 285

Query: 308 PGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQ 361
           P    P+SPSQ RKGPPVPP PK TP+KE++QE I+S FED FVPEISVTTPSQ
Sbjct: 286 PAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQ 339



 Score =  109 bits (273), Expect = 5e-24
 Identities = 73/228 (32%), Positives = 106/228 (46%), Gaps = 28/228 (12%)

Query: 282 SPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQ 341
           S  +G+P    E      P   G +   A   K  ++  +G     P        V QE+
Sbjct: 440 SAAEGAPGEEAEAEKATVPAGEGVSLEEA---KIGTETTEGAESAQPEAEELEATVPQEK 496

Query: 342 ILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQ--EPGETAASEAASSSLPAVVV 399
           +        +P + +    +PA   E  G  +   GA+  E  E AA    +S  P +  
Sbjct: 497 V--------IPSVVI----EPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELAT 544

Query: 400 ETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDYTATDTDELQLKAG 448
           E  P             G  D           LPPGF++KV+  HD+ A ++DEL L+ G
Sbjct: 545 EQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRG 604

Query: 449 DVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 496
           DVVLV+P  +  +QD GWL+GVKESDW Q+++L   +G+FPENFT R+
Sbjct: 605 DVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRL 652


>gi|4502081 amphiphysin isoform 1 [Homo sapiens]
          Length = 695

 Score =  424 bits (1091), Expect = e-119
 Identities = 216/354 (61%), Positives = 261/354 (73%), Gaps = 19/354 (5%)

Query: 9   VTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTY 68
           +  G  A NVQK+L RAQEKVLQKLGKADETKDEQFE+ VQNF +Q  EGTRLQ++LR Y
Sbjct: 4   IKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGY 63

Query: 69  LASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDT 128
           LA++K M EAS KL E L EVYEPDW GR++   + E  D+LW D+HQKLVD +LLT+DT
Sbjct: 64  LAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDT 123

Query: 129 YLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEM 188
           YLGQFPDIK+RIAKR RKLVDYDSARHH E+LQ++K+KDE++I+KAEEE  KAQKVFEE 
Sbjct: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183

Query: 189 NVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTF 248
           NVDLQEELPSLW+ RVGFYVNTF++++ LE  FHKE++ L   L +V+  L  QH    F
Sbjct: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAF 243

Query: 249 TVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPP-DGSPAATPEIRVNHEPEPAGGAT 307
           T++  P               SD+ P +  K+PSPP + SP  +P    NH   P   A+
Sbjct: 244 TIQGAP---------------SDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAP---AS 285

Query: 308 PGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQ 361
           P    P+SPSQ RKGPPVPP PK TP+KE++QE I+S FED FVPEISVTTPSQ
Sbjct: 286 PAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQ 339



 Score =  109 bits (273), Expect = 5e-24
 Identities = 73/228 (32%), Positives = 106/228 (46%), Gaps = 28/228 (12%)

Query: 282 SPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQ 341
           S  +G+P    E      P   G +   A   K  ++  +G     P        V QE+
Sbjct: 482 SAAEGAPGEEAEAEKATVPAGEGVSLEEA---KIGTETTEGAESAQPEAEELEATVPQEK 538

Query: 342 ILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQ--EPGETAASEAASSSLPAVVV 399
           +        +P + +    +PA   E  G  +   GA+  E  E AA    +S  P +  
Sbjct: 539 V--------IPSVVI----EPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELAT 586

Query: 400 ETFPATVNGTVEGGSGAGRLD-----------LPPGFMFKVQAQHDYTATDTDELQLKAG 448
           E  P             G  D           LPPGF++KV+  HD+ A ++DEL L+ G
Sbjct: 587 EQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRG 646

Query: 449 DVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 496
           DVVLV+P  +  +QD GWL+GVKESDW Q+++L   +G+FPENFT R+
Sbjct: 647 DVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRL 694


>gi|49472835 bridging integrator 2 [Homo sapiens]
          Length = 565

 Score =  314 bits (805), Expect = 1e-85
 Identities = 185/415 (44%), Positives = 248/415 (59%), Gaps = 26/415 (6%)

Query: 1   MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR 60
           MAE G  G  AG  A  VQKK +RAQEKVLQKLGKA ETKDE+FEQ   NF +Q  EG +
Sbjct: 1   MAE-GKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHK 59

Query: 61  LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD 120
           L KDL+ +L++VK MHE+SK+++E LQE+Y  +W G +E   I  NNDLLW DY +KL D
Sbjct: 60  LYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLAD 119

Query: 121 QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIK 180
           QA+ TM+ Y+ QF +IK RIAKRGRKLVDYDSARHH E++Q AKKKDEAK AKAEEE  K
Sbjct: 120 QAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNK 179

Query: 181 AQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLE 240
           AQ VFE++N +L EELP L+NSR+G YV  FQ+I+ L + F++EMSKLN NL +V+  LE
Sbjct: 180 AQTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLE 239

Query: 241 KQHGSNTFTVK---------------------AQPRKKSKLFSRLRRKKNSDNAPAKGNK 279
           KQH +  F VK                     + P       S L  K  S++  A  + 
Sbjct: 240 KQHSNKVFVVKGLSSSSRRSLVISPPVRTATVSSPLTSPTSPSTLSLKSESESVSATEDL 299

Query: 280 SPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQ 339
           +P    G   +  +  +  E     G+   ++    P     G P    P  T  +   Q
Sbjct: 300 APDAAQGEDNSEIKELLEEEEIEKEGSEASSSEEDEPLPACNG-PAQAQPSPTTERAKSQ 358

Query: 340 EQILSLFEDTFVPEISVTTPSQP-AEASEVAGGTQPAA-GAQEPGETAASEAASS 392
           E++L     T  P  +++   QP + A+EV   T+ A+ G+++P + A+ +  S+
Sbjct: 359 EEVLP-SSTTPSPGGALSPSGQPSSSATEVVLRTRTASEGSEQPKKRASIQRTSA 412


>gi|8923904 bridging integrator 3 [Homo sapiens]
          Length = 253

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 55/195 (28%), Positives = 100/195 (51%), Gaps = 14/195 (7%)

Query: 53  KQLTEGTR-LQKDLRTYLASVKAMHEASKKLNECL--QEVYEPDWPGRDEANKI-AENND 108
           +QL E TR LQKD++    +  AM +++ K++  L    + E D   +D  N + A +  
Sbjct: 32  QQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQD---QDLLNMVTALDTA 88

Query: 109 LLWMD-YHQKLVDQALLTMDTYLGQF----PDIKSRIAKRGRKLVDYDSARHHYESLQTA 163
           +  MD ++Q+ V+Q   T+   L +F    P +   + +R + L DY   +   E  +  
Sbjct: 89  MKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEKYEEK 148

Query: 164 KKKDE--AKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENF 221
           +K     AK+ +A EEL   ++ FE  N  L EE+P  + SR+ ++  +F+S+   +  +
Sbjct: 149 EKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRAQVVY 208

Query: 222 HKEMSKLNQNLNDVL 236
           + EM K+  +L+  L
Sbjct: 209 YSEMHKIFGDLSHQL 223


>gi|39930351 dynamin binding protein [Homo sapiens]
          Length = 1577

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 50/223 (22%), Positives = 90/223 (40%), Gaps = 18/223 (8%)

Query: 17   NVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYLASVKA-- 74
            ++ KK  R    +    G A + KDE FE+  +NF  Q        +DL  YL  ++   
Sbjct: 996  SIIKKSNRVSSHLKHLTGFAPQIKDEVFEETEKNFRMQERLIKSFIRDLSLYLQHIRESA 1055

Query: 75   ---MHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDTYLG 131
               +  A    + C++  +  D    +  ++    +D L+ ++ ++     +  ++  L 
Sbjct: 1056 CVKVVAAVSMWDVCMERGHR-DLEQFERVHRYI--SDQLFTNFKERTERLVISPLNQLLS 1112

Query: 132  QFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEMNVD 191
             F      + KR  KL+D+ +     E L         K  K  EEL  A+  +E +N  
Sbjct: 1113 MFTGPHKLVQKRFDKLLDFYNCTERAEKL---------KDKKTLEELQSARNNYEALNAQ 1163

Query: 192  LQEELPSLWNSRVGFYVNTFQSIAGLEENF-HKEMSKLNQNLN 233
            L +ELP       G + N     A    +F H+ + +L   L+
Sbjct: 1164 LLDELPKFHQYAQGLFTNCVHGYAEAHCDFVHQALEQLKPLLS 1206



 Score = 35.8 bits (81), Expect = 0.092
 Identities = 25/81 (30%), Positives = 35/81 (43%), Gaps = 15/81 (18%)

Query: 414 SGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKES 473
           S +    +P   M + +A    +A   +EL  + GDV+ +I    P     GW  G    
Sbjct: 135 SQSALFQIPEYSMGQARALMGLSAQLDEELDFREGDVITIIGVPEP-----GWFEG---- 185

Query: 474 DWNQHKELEKCRGVFPENFTE 494
                 ELE  RG+FPE F E
Sbjct: 186 ------ELEGRRGIFPEGFVE 200



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 15/68 (22%)

Query: 429 VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVF 488
           V+A  D+  + ++EL L  GD++ V+        DE WL+G KE             G F
Sbjct: 7   VRAIFDFCPSVSEELPLFVGDIIEVLAV-----VDEFWLLGKKED----------VTGQF 51

Query: 489 PENFTERV 496
           P +F E V
Sbjct: 52  PSSFVEIV 59


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 40/128 (31%), Positives = 49/128 (38%), Gaps = 21/128 (16%)

Query: 273  APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHT 332
            AP     +P  P G PA +P         P G  TP A  P SP    KG P  PPPK  
Sbjct: 1286 APNPAVVTPPSPKGGPATSP---------PKGAPTPPAATPPSP----KGSPGTPPPKGA 1332

Query: 333  PSKEVKQEQILSLFEDTFVPEISVTTPSQ---PAEASEVAGGTQPAAGAQEPGETAASEA 389
            P+        ++       P +  TTPS    P   S   G T PAA     G  A +  
Sbjct: 1333 PTPPA-----VTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPP 1387

Query: 390  ASSSLPAV 397
            +    PA+
Sbjct: 1388 SPKRGPAI 1395



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 37/138 (26%), Positives = 46/138 (33%), Gaps = 31/138 (22%)

Query: 273  APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHT 332
            AP     +P  P G PA          P P G  TP A  P SP    KG P  P PK  
Sbjct: 962  APTPPAATPPSPKGGPAT---------PSPKGAPTPPAATPPSP----KGGPATPSPKGA 1008

Query: 333  PSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGG--TQPAAGAQEPGETAASEAA 390
            P+                 P ++  +P     A+    G  T PAA    P  + A+   
Sbjct: 1009 PTP----------------PAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052

Query: 391  SSSLPAVVVETFPATVNG 408
                P     T P+   G
Sbjct: 1053 PKGAPTTPAATLPSPKGG 1070



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 44/156 (28%), Positives = 56/156 (35%), Gaps = 26/156 (16%)

Query: 276  KGNKSPSPPDGSP---AATPEIRVNHE--PEPAGGATPGATLPKSPSQLRKGPPVPPPPK 330
            KG  + SPP G+P   AATP         P P G  TP A  P SP      P   P  K
Sbjct: 1298 KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK 1357

Query: 331  HTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAA 390
              P+    +E                  P+ PA      GG      + + G    S   
Sbjct: 1358 GGPTTPSSKE-----------------GPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKG 1400

Query: 391  SSSLPAVV---VETFPATVNGTVEGGSGAGRLDLPP 423
              + PAV+    +  PAT   T EG +   + DL P
Sbjct: 1401 DPTSPAVIPLSPKKAPAT-PVTREGAATPSKGDLTP 1435



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 41/132 (31%), Positives = 48/132 (36%), Gaps = 17/132 (12%)

Query: 273  APAKGNKSPSPPDG--SPAATPEIRVNH--EPEPAGGATPGATLPKSPSQLRKGPPVPPP 328
            +P  G  +PSP     +PAATP         P P G  T  A  P SP    KG P  PP
Sbjct: 1204 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP----KGGPATPP 1259

Query: 329  PKHTPSKEVKQEQI----LSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGA-QEPGE 383
            PK  P+            L+       P  +V TP  P    +    T P  GA   P  
Sbjct: 1260 PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP----KGGPATSPPKGAPTPPAA 1315

Query: 384  TAASEAASSSLP 395
            T  S   S   P
Sbjct: 1316 TPPSPKGSPGTP 1327



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 38/133 (28%), Positives = 47/133 (35%), Gaps = 29/133 (21%)

Query: 273  APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHT 332
            AP     +P  P GSPAATP         P G +TP A  P SP   +  P   P PK  
Sbjct: 1008 APTPPAVTPPSPKGSPAATPF--------PKGASTPPAATPPSP---KGSPAATPLPKGA 1056

Query: 333  PSKEVKQEQILSLFEDTFVPEISVTTP-SQPAEASEVAGGTQPAAGAQEP-GETAASEAA 390
            P+                 P  ++ +P   PA  S     T PAA    P G  A     
Sbjct: 1057 PT----------------TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK 1100

Query: 391  SSSLPAVVVETFP 403
             + +P       P
Sbjct: 1101 GAPMPPAATPPSP 1113



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 39/130 (30%), Positives = 45/130 (34%), Gaps = 28/130 (21%)

Query: 273  APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHT 332
            APA    S SP        P+  +   P P G  TP A  P SP    KG P  P PK  
Sbjct: 908  APALSMTSSSPKKARATPAPK-GIPASPSPKGAPTPPAATPPSP----KGGPATPSPKWA 962

Query: 333  PSKEVKQEQILSLFEDTFVPEISVTTPSQ---PAEASEVAGGTQPAAGAQEP--GETAAS 387
            P+                    + T PS    PA  S     T PAA    P  G    S
Sbjct: 963  PTPP------------------AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPS 1004

Query: 388  EAASSSLPAV 397
               + + PAV
Sbjct: 1005 PKGAPTPPAV 1014



 Score = 36.6 bits (83), Expect = 0.054
 Identities = 39/143 (27%), Positives = 50/143 (34%), Gaps = 15/143 (10%)

Query: 273  APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHT 332
            AP     +P  P G PA          P P G   P A  P SP    KG    PP K  
Sbjct: 1079 APTPPAATPPSPKGGPAT---------PSPKGAPMPPAATPPSP----KGGLATPPHKGA 1125

Query: 333  PSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGA-QEPGETAASEAAS 391
            P+              T  P+ + TTP+    + +    T P  GA   P  T  S    
Sbjct: 1126 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1185

Query: 392  SSLPAVV-VETFPATVNGTVEGG 413
             + P+     T PA    + +GG
Sbjct: 1186 LATPSPKGAPTTPAATPPSPKGG 1208



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 33/98 (33%), Positives = 39/98 (39%), Gaps = 22/98 (22%)

Query: 300 PEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPS-------KE------VKQEQILSLF 346
           P P G  TP A  P SP    KG  +PP    TPS       KE       KQ   LS+ 
Sbjct: 859 PSPKGAPTPSAVTPLSP----KGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMT 914

Query: 347 EDTFVPEISVTTPSQ---PAEASEVAGGTQPAAGAQEP 381
             +  P+ +  TP+    PA  S     T PAA    P
Sbjct: 915 SSS--PKKARATPAPKGIPASPSPKGAPTPPAATPPSP 950



 Score = 33.1 bits (74), Expect = 0.60
 Identities = 34/140 (24%), Positives = 56/140 (40%), Gaps = 19/140 (13%)

Query: 274  PAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGP-----PVPPP 328
            P    + P+P   + +++P+ +    P P G  T  A +P SP ++   P     P+ P 
Sbjct: 1472 PPSPKEPPAPKQVATSSSPK-KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPT 1530

Query: 329  ----PKHTPSKEVKQEQILSLFEDTFVPE--ISVTTPSQ-PAEASEVAGGTQPAA----- 376
                 K TP+    +E ++        P+   ++ TP + PA  S     + PA      
Sbjct: 1531 ATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY 1590

Query: 377  -GAQEPGETAASEAASSSLP 395
             GA  P E     A +S  P
Sbjct: 1591 KGAPSPKELLIPPAVTSPSP 1610



 Score = 32.7 bits (73), Expect = 0.78
 Identities = 40/167 (23%), Positives = 59/167 (35%), Gaps = 20/167 (11%)

Query: 274  PAKGNKSP--SPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQL------RKGPPV 325
            P    K+P  S P G PA TP  +   +P       P    P +P Q+      +K P  
Sbjct: 1440 PVSLKKAPATSAPKGGPA-TPSSK--GDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPAT 1496

Query: 326  PPP------PKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQ 379
            P P      P   PS   +     S   D   P  ++ +   PA  +       PA    
Sbjct: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVP 1556

Query: 380  EPGETAA---SEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPP 423
             P +T A    + A ++  +    + PA    T +G      L +PP
Sbjct: 1557 SPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPP 1603



 Score = 29.6 bits (65), Expect = 6.6
 Identities = 43/167 (25%), Positives = 58/167 (34%), Gaps = 29/167 (17%)

Query: 264  LRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHE----PEPAGGATPGATLPK----- 314
            L +K  +  AP +    P+    SP  TP I    E    P     ++P A  P      
Sbjct: 1534 LSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGA 1593

Query: 315  -SPSQLRKGPPV--------PPPPKHTPSKEVKQEQILSLFEDTFVPEISVT----TPSQ 361
             SP +L   P V        P PP  TP    K     +       P ++ +    +P+ 
Sbjct: 1594 PSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTS 1653

Query: 362  PAEASEVAGGTQPAAGAQEP---GETAASEA----ASSSLPAVVVET 401
            PA  +   G T P A    P   G TA  E     A  S P +   T
Sbjct: 1654 PASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPT 1700


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
           sapiens]
          Length = 2524

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 63/243 (25%), Positives = 92/243 (37%), Gaps = 34/243 (13%)

Query: 214 IAGLEENFHKEMSKLNQNLNDVLVG-----LEKQHGSNTFTVKAQPRKKSKLFSRLRRKK 268
           ++G EE   +E   L+ + N+V  G         + S+T ++ +   + +K        +
Sbjct: 710 VSGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAK-----DTGQ 764

Query: 269 NSDNAPAKGNKSPSPPDGSPAATPE-IRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPP 327
           N    PA    +  PP G P   PE I    EP PA  AT   T P +P      PPV P
Sbjct: 765 NGPKPPATLG-ADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVP 823

Query: 328 PPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAAS 387
                  KE K+E      E    P +      +P  A E+A  T     A+EP ++  +
Sbjct: 824 -------KEEKEE------ETAAAPPVEEGEEQKPPAAEELAVDT---GKAEEPVKSECT 867

Query: 388 EAASSS-LPAVVVETFPATVNGTV-----EGGSGAGRLDLPPGFMFKVQAQHDYTATDTD 441
           E A          E   AT  G +     EGGSG        G      +    +A + D
Sbjct: 868 EEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVD 927

Query: 442 ELQ 444
           E +
Sbjct: 928 EAE 930


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
           sapiens]
          Length = 2462

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 49/169 (28%), Positives = 63/169 (37%), Gaps = 23/169 (13%)

Query: 283 PPDGSPAATPE-IRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQ 341
           PP G P   PE I    EP PA  AT   T P +P      PPV P       KE K+E 
Sbjct: 761 PPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVP-------KEEKEE- 812

Query: 342 ILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSS-LPAVVVE 400
                E    P +      +P  A E+A  T     A+EP ++  +E A          E
Sbjct: 813 -----ETAAAPPVEEGEEQKPPAAEELAVDT---GKAEEPVKSECTEEAEEGPAKGKDAE 864

Query: 401 TFPATVNGTV-----EGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ 444
              AT  G +     EGGSG        G      +    +A + DE +
Sbjct: 865 AAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAE 913



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 61/278 (21%), Positives = 97/278 (34%), Gaps = 53/278 (19%)

Query: 127 DTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFE 186
           D   G+  D K  +A +GRK  +    R   +   T    +EA      EE I  Q+  E
Sbjct: 551 DDTSGEDNDEKEAVASKGRKTANSQGRR---KGRITRSMANEAN----SEEAITPQQSAE 603

Query: 187 EMNVDLQEELPSLWN------SRVGF--YVNTFQSIAGLE--------ENFHKEMSKLNQ 230
             +++L E   S W       ++ G   +   + +IA +         +NF+    K  Q
Sbjct: 604 LASMELNES--SRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKK-RQ 660

Query: 231 NLNDVL----VGLEKQHGSNTFTVKAQPRKKSKL-FSRLRRKKNSDNAPAKGNKSPSPPD 285
           NL+++L    + +EK+  +     KA      +  F  +   +  + +   GN+     +
Sbjct: 661 NLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEE 720

Query: 286 GSPAATPEIRVNHEPEPAGGATP--GATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQIL 343
                         P P   A    G   PK P+ L    P P PP  TP          
Sbjct: 721 AEATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPP--TP---------- 768

Query: 344 SLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEP 381
                   P   +  P++P  ASE  G   P      P
Sbjct: 769 --------PPEDIPAPTEPTPASEATGAPTPPPAPPSP 798


>gi|49640014 ubiquitin associated and SH3 domain containing, A short
           form [Homo sapiens]
          Length = 623

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 9/67 (13%)

Query: 429 VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVF 488
           ++A   Y   + DEL L  GD + V P Q  +E  EGW++G+ +           CRG  
Sbjct: 243 LRALFQYKPQNVDELTLSPGDYIFVDPTQQ-DEASEGWVIGISQR--------TGCRGFL 293

Query: 489 PENFTER 495
           PEN+T+R
Sbjct: 294 PENYTDR 300


>gi|9507221 ubiquitin associated and SH3 domain containing, A long
           form [Homo sapiens]
          Length = 661

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 9/67 (13%)

Query: 429 VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVF 488
           ++A   Y   + DEL L  GD + V P Q  +E  EGW++G+ +           CRG  
Sbjct: 281 LRALFQYKPQNVDELTLSPGDYIFVDPTQQ-DEASEGWVIGISQR--------TGCRGFL 331

Query: 489 PENFTER 495
           PEN+T+R
Sbjct: 332 PENYTDR 338


>gi|109689723 abl interactor 2 [Homo sapiens]
          Length = 475

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 60/237 (25%), Positives = 81/237 (34%), Gaps = 55/237 (23%)

Query: 280 SPSPPDGSPAATPEI------RVNHEPEPAGGATPGATLPKSPSQ------LRKGP---- 323
           +PSPP   P    +          H P   GG+ P    P   SQ      +  GP    
Sbjct: 269 TPSPPSVFPGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQMNGGPFYSQ 328

Query: 324 -PV---PPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQ 379
            PV   PPPP      +V  +  L  F       IS T P  P     V   + P     
Sbjct: 329 NPVSLAPPPPSIL---QVTPQLPLMGFVARVQENISDTPPPPPPVEEPVFDESPPPPPPP 385

Query: 380 EPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATD 439
           E  E   +     S P    E  P                  P  ++ KV A +DYT   
Sbjct: 386 EDYEEEEAAVVEYSDP--YAEEDPPWA---------------PRSYLEKVVAIYDYTKDK 428

Query: 440 TDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 496
            DEL  + G ++ VI     ++ D+GW  GV          +    G+FP N+ E +
Sbjct: 429 EDELSFQEGAIIYVI-----KKNDDGWYEGV----------MNGVTGLFPGNYVESI 470


>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
           [Homo sapiens]
          Length = 1132

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 41/136 (30%), Positives = 54/136 (39%), Gaps = 13/136 (9%)

Query: 274 PAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTP 333
           P  G   P PP   P   P     H P       PG   P  P  +   PPV  PP HTP
Sbjct: 694 PGFGPGVPPPPPPPPFLRPGFNPMHLP-------PGFLPPGPPPPIT--PPVSIPPPHTP 744

Query: 334 SKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSS 393
              +    I  + EDT   ++S+  P  P   S   G  +     +  G +A   AA ++
Sbjct: 745 PISIPNSTIAGINEDT-TKDLSIGNPI-PTVVSGARGNAESGDSVKMYG-SAVPPAAPTN 801

Query: 394 LPAVVVETFPATVNGT 409
           LP   V T P ++ GT
Sbjct: 802 LPTPPV-TQPVSLLGT 816


>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
           [Homo sapiens]
          Length = 1147

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 41/136 (30%), Positives = 54/136 (39%), Gaps = 13/136 (9%)

Query: 274 PAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTP 333
           P  G   P PP   P   P     H P       PG   P  P  +   PPV  PP HTP
Sbjct: 709 PGFGPGVPPPPPPPPFLRPGFNPMHLP-------PGFLPPGPPPPIT--PPVSIPPPHTP 759

Query: 334 SKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSS 393
              +    I  + EDT   ++S+  P  P   S   G  +     +  G +A   AA ++
Sbjct: 760 PISIPNSTIAGINEDT-TKDLSIGNPI-PTVVSGARGNAESGDSVKMYG-SAVPPAAPTN 816

Query: 394 LPAVVVETFPATVNGT 409
           LP   V T P ++ GT
Sbjct: 817 LPTPPV-TQPVSLLGT 831


>gi|115527120 nebulin [Homo sapiens]
          Length = 6669

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 38/154 (24%), Positives = 62/154 (40%), Gaps = 39/154 (25%)

Query: 360  SQPAEASEVAGGTQPAAGAQEPGE--------------TAASEAASSSLP---AVVVETF 402
            S+ A A  ++GG + +  ++ P                TA   A ++ LP   +  V T 
Sbjct: 6538 SRSASALSISGGEEKSEHSEAPDHHLSTYSDGGVFAVSTAYKHAKTTELPQQRSSSVATQ 6597

Query: 403  PATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQ 462
              TV+      S AG++          +A +DY A D DE+  K GD ++     N +  
Sbjct: 6598 QTTVSSIPSHPSTAGKI---------FRAMYDYMAADADEVSFKDGDAII-----NVQAI 6643

Query: 463  DEGWLMGVKESDWNQHKELEKCRGVFPENFTERV 496
            DEGW+ G  +             G+ P N+ E +
Sbjct: 6644 DEGWMYGTVQRTGR--------TGMLPANYVEAI 6669


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 37/124 (29%), Positives = 52/124 (41%), Gaps = 18/124 (14%)

Query: 273 APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHT 332
           A A G    +P +G+P A P      EP PAG A PG   P+ P       P+ P     
Sbjct: 68  AGAAGAGPAAPAEGAPGAAP------EPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAP 121

Query: 333 PSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPA-AGAQEPGETAASEAAS 391
           P+ +++             PE S  + +    A+ VA G +PA AG  +P   AA  A +
Sbjct: 122 PAAKLRPP-----------PEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARA 170

Query: 392 SSLP 395
              P
Sbjct: 171 GPGP 174



 Score = 36.2 bits (82), Expect = 0.071
 Identities = 41/156 (26%), Positives = 52/156 (33%), Gaps = 35/156 (22%)

Query: 271 DNAPAKGNKSPSPP-DGSPAATPE-IRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPP 328
           +N PA     P P   G+   TP  +     P PA  + P A  P +P+     PP PPP
Sbjct: 219 NNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPA---AAPPPPPP 275

Query: 329 PKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASE 388
                                  P      P  PA     A    P A AQ  G   A+ 
Sbjct: 276 ----------------------APATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAP 313

Query: 389 AASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPG 424
           A + +         PA V+G  + G GA      PG
Sbjct: 314 APAPAAGG------PAGVSG--QPGPGAAAAAPAPG 341



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 21/62 (33%), Positives = 24/62 (38%)

Query: 273 APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHT 332
           APA G K+ SP     AA P  +      PA  A      P     L     VPPP   T
Sbjct: 337 APAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGT 396

Query: 333 PS 334
           P+
Sbjct: 397 PT 398


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 32/118 (27%), Positives = 41/118 (34%), Gaps = 7/118 (5%)

Query: 264  LRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGAT----LPKSPSQL 319
            L  +K     P      P PP   P   P +     P P    TP +     LP  P   
Sbjct: 1452 LLEEKPPPTPPPAPTPQPQPPPPPPPPQPALP---SPPPLVAPTPSSPPPPPLPPPPPPA 1508

Query: 320  RKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAG 377
               PP PPPP   P     +E      ED  +P+      ++  E + V G T   AG
Sbjct: 1509 MPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAG 1566



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 51/208 (24%), Positives = 68/208 (32%), Gaps = 21/208 (10%)

Query: 271  DNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPP-- 328
            D+ P  G K  S PDG P A         P P   +      P+ P    K PP PPP  
Sbjct: 1406 DDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAP 1465

Query: 329  --------PKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAG-AQ 379
                    P   P   +     L     +  P   +  P  PA  S        AA  A 
Sbjct: 1466 TPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAA 1525

Query: 380  EPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATD 439
             P E AA       LP    +T P  +    E  +  G  D   G     ++  +    +
Sbjct: 1526 PPEEPAAPSPEDPELP----DTRPLHLAKKQETAAVCGETDEEAG-----ESGGEGIFRE 1576

Query: 440  TDELQLKAGDV-VLVIPFQNPEEQDEGW 466
             DE  ++A D+  L +  Q   E    W
Sbjct: 1577 RDEFVIRAEDIPSLKLALQTGREPPPIW 1604



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 19/66 (28%), Positives = 25/66 (37%), Gaps = 4/66 (6%)

Query: 277  GNKSPSPPDGSPAATPEIRVNHEPEP----AGGATPGATLPKSPSQLRKGPPVPPPPKHT 332
            G   P    G+   TP + ++    P       A P   +   P Q    PP PPPP   
Sbjct: 991  GPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPA 1050

Query: 333  PSKEVK 338
            P+ E K
Sbjct: 1051 PASEPK 1056



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 37/145 (25%), Positives = 52/145 (35%), Gaps = 20/145 (13%)

Query: 281 PSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQE 340
           P PP   P   P + ++H P P+  A+        P+     P  PPPP   P     Q 
Sbjct: 795 PPPP---PQLLPSV-LSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQ- 849

Query: 341 QILSLFEDTFVPEISVTTPS-QPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVV 399
             L     +   E +  +P  +P E+ +  G  Q   GA EP            LP    
Sbjct: 850 --LEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEP------------LPPAPG 895

Query: 400 ETFPATVNGTVEGGSGAGRLDLPPG 424
           +T     N   +  +GA R   P G
Sbjct: 896 DTGVGPPNSEGKDPAGAYRSPSPQG 920



 Score = 29.6 bits (65), Expect = 6.6
 Identities = 24/67 (35%), Positives = 28/67 (41%), Gaps = 5/67 (7%)

Query: 274 PAKGNKSPSPP---DGSPAATPEIRVNHEPEPAGGATPGATL-PKSPSQLRKGPP-VPPP 328
           PA G  SP        S A T    +  E    GG    A L P      R GPP  PPP
Sbjct: 178 PANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPP 237

Query: 329 PKHTPSK 335
           P+H P++
Sbjct: 238 PRHLPTQ 244


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 42/151 (27%), Positives = 57/151 (37%), Gaps = 16/151 (10%)

Query: 273  APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKH- 331
            +PA    +P  P    AA P      EP     A P    P SP+     P  P  P   
Sbjct: 1067 SPAAAVPTPEEPTSPAAAVP---TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAA 1123

Query: 332  --TPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVA----GGTQPAAGAQEPGETA 385
              TP +       +   E+   P  +V TP + A A+           PAA    P E+A
Sbjct: 1124 VPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESA 1183

Query: 386  ASEAASSSL-----PAVVVETFPATVNGTVE 411
            +  A  ++L     PA  V T PA +  T+E
Sbjct: 1184 SFAAVVATLEEPTSPAASVPT-PAAMVATLE 1213



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 44/161 (27%), Positives = 56/161 (34%), Gaps = 20/161 (12%)

Query: 273  APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKH- 331
            +PA    +P  P    AA P      EP     A P    P SP+     P  P  P   
Sbjct: 1002 SPAAAVPTPEEPTSPAAAVP---TPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAA 1058

Query: 332  --TPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVA----GGTQPAAGAQEPGETA 385
              TP +       +   E+   P  +V TP +P   +         T PAA    P E A
Sbjct: 1059 VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPA 1118

Query: 386  ASEAA-----SSSLPAVVVET-----FPATVNGTVEGGSGA 416
            +  AA       + PA  V T     FPA    T E  + A
Sbjct: 1119 SPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASA 1159



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 44/168 (26%), Positives = 59/168 (35%), Gaps = 21/168 (12%)

Query: 273  APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKH- 331
            +PA    +P  P    AA P      EP     A P    P SP+     P  P  P   
Sbjct: 1041 SPAAAVPTPEEPTSPAAAVP---TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1097

Query: 332  --TPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQ----PAAGAQEPGETA 385
              TP +       +   E+   P  +V TP +PA  +      +    PA     P E+A
Sbjct: 1098 VPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESA 1157

Query: 386  ASEAA-----SSSLPAVVVET------FPATVNGTVEGGSGAGRLDLP 422
            ++  A      S+ PA  V T      F A V    E  S A  +  P
Sbjct: 1158 SAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTP 1205



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 39/143 (27%), Positives = 56/143 (39%), Gaps = 13/143 (9%)

Query: 273  APAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQL---RKGPPVPPPP 329
            +PA    +P  P    AA P      EP     A P    P SP+      + P  P P 
Sbjct: 1093 SPAAAVPTPEEPTSPAAAVP---TPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPA 1149

Query: 330  KHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEA 389
              TP +       +   E++  P  +V TP++ A  + V       A  +EP   AAS  
Sbjct: 1150 VPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVV------ATLEEPTSPAASVP 1203

Query: 390  ASSSLPAVVVE-TFPATVNGTVE 411
              +++ A + E T PA    T E
Sbjct: 1204 TPAAMVATLEEFTSPAASVPTSE 1226



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 41/156 (26%), Positives = 54/156 (34%), Gaps = 35/156 (22%)

Query: 274  PAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGA----------TPGATLPKSPSQLRKGP 323
            PA    +P  PD     T  +RV+   EPA  A          +P A +P          
Sbjct: 977  PATTVHAPEEPD-----TAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1031

Query: 324  PVPPPPKHT--------PSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPA 375
             VPPP + T        P +       +   E+   P  +V TP +P         T PA
Sbjct: 1032 AVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP---------TSPA 1082

Query: 376  AGAQEPGETAASEAASSSLPAVVVETFPATVNGTVE 411
            A    P E  +  AA   +P     T PA    T E
Sbjct: 1083 AAVPTPEEPTSPAAA---VPTPEEPTSPAAAVPTPE 1115



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 35/139 (25%), Positives = 47/139 (33%), Gaps = 12/139 (8%)

Query: 282  SPPDGSPAATPEIRVNHEPEPAGGATPGATLP-----KSPSQLRKGPPVPPPPKHTPSKE 336
            SP + +PA    I        AG +   A L             +GP  P    H P + 
Sbjct: 928  SPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEP 987

Query: 337  VKQEQILSLFEDTFVPEISVTTPSQPAEASEVA----GGTQPAAGAQEPGETAASEAASS 392
                  +S  E+   P  +V TP +P   +         T PAA    P E  +  AA  
Sbjct: 988  DTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAA-- 1045

Query: 393  SLPAVVVETFPATVNGTVE 411
             +P     T PA    T E
Sbjct: 1046 -VPTPEEPTSPAAAVPTPE 1063


>gi|194578923 sperm associated antigen 9 isoform 1 [Homo sapiens]
          Length = 1321

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 65/289 (22%), Positives = 110/289 (38%), Gaps = 25/289 (8%)

Query: 135 DIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKAEEELIKAQKVFEEMNVDLQE 194
           ++ S  A+     V+ +  R   E L T  ++++A    AEE+ I+ +   E+   DLQ 
Sbjct: 60  NLDSVFAQDQEHQVELELLRDDNEQLITQYEREKALRKHAEEKFIEFEDSQEQEKKDLQT 119

Query: 195 ELPSLWNS------RVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVG-LEKQHGSNT 247
            + SL +       +   Y +    +   E    KE + L+Q   +++   +E    +  
Sbjct: 120 RVESLESQTRQLELKAKNYADQISRLEEREAELKKEYNALHQRHTEMIHNYMEHLERTKL 179

Query: 248 FTVKAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGAT 307
             +    + +S   SR+R+++     P      P P  G    TP+ +        GG T
Sbjct: 180 HQLSGSDQLESTAHSRIRKER-----PISLGIFPLPA-GDGLLTPDAQ-------KGGET 226

Query: 308 PGATLPK--SPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEA 365
           PG+   K    SQ R    +       P K V+QE  LS   D        TTP+  A +
Sbjct: 227 PGSEQWKFQELSQPRSHTSLKVSNSPEPQKAVEQEDELS---DVSQGGSKATTPASTANS 283

Query: 366 SEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGS 414
                 T      +  G    ++A + S  +  +E   A     V  GS
Sbjct: 284 DVATIPTDTPLKEENEGFVKVTDAPNKSEISKHIEVQVAQETRNVSTGS 332


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 42/162 (25%), Positives = 63/162 (38%), Gaps = 24/162 (14%)

Query: 237 VGLEKQHGSNTFTVKAQPRKKSKLFS-RLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIR 295
           VG  ++H S + +    PRK+ K  S R RR+++    P +  +SP     SPA  P  R
Sbjct: 517 VGRRRRH-SPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSP-----SPAPPPRRR 570

Query: 296 VNHEPEPAGGATPGATLPKSPSQLRKGPPV-----------------PPPPKHTPSKEVK 338
               P P           +SPS  R  PP+                 PPPPK   S    
Sbjct: 571 RTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPP 630

Query: 339 QEQILSLFEDTFVPEISVTTPSQPAEASEVAGGTQPAAGAQE 380
            ++ +S           VT    P+ +S+   G+ P+   +E
Sbjct: 631 PKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTRE 672



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 4/85 (4%)

Query: 254 PRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLP 313
           PR +       RR+++S +     + S S    SP   P  R +  P      +P A+ P
Sbjct: 336 PRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPP 395

Query: 314 KSPSQLRKGPPVPPPPK--HTPSKE 336
           +   + R  PP  PPPK  H+P+ +
Sbjct: 396 RR--RHRPSPPATPPPKTRHSPTPQ 418



 Score = 37.0 bits (84), Expect = 0.041
 Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 8/92 (8%)

Query: 254 PRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGAT-PGATL 312
           PR++S    R  RK++   +P    KS SP   SPA   + +    PEP+     P    
Sbjct: 182 PRRRSSPVRR-ERKRSHSRSPRHRTKSRSP---SPAPEKKEKTPELPEPSVKVKEPSVQE 237

Query: 313 PKSPSQLRKGP---PVPPPPKHTPSKEVKQEQ 341
             S S + K P   P+P P + +P K  K+E+
Sbjct: 238 ATSTSDILKVPKPEPIPEPKEPSPEKNSKKEK 269



 Score = 35.8 bits (81), Expect = 0.092
 Identities = 33/136 (24%), Positives = 51/136 (37%), Gaps = 21/136 (15%)

Query: 253 QPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDG----SPAATPEIRVNHEPEP-----A 303
           QP K+     R R  + S + P     + S P      SP+  P  RV+  PEP     A
Sbjct: 677 QPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKA 736

Query: 304 GGATPGA--------TLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEIS 355
              +P +        ++  SP    K PP PP P  + S        + + +     +  
Sbjct: 737 ASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKK----AKSP 792

Query: 356 VTTPSQPAEASEVAGG 371
             +PS P  + +  GG
Sbjct: 793 TPSPSPPRNSDQEGGG 808



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 25/87 (28%), Positives = 37/87 (42%), Gaps = 21/87 (24%)

Query: 251 KAQPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGA 310
           + + R +SK  SR R +  S   P + ++S S    SP   P  R               
Sbjct: 275 RPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSR-SYSPRRRPSPR--------------- 318

Query: 311 TLPKSPSQLRKGPP--VPPPPKHTPSK 335
              + PS  R+ PP  +PPPP+H  S+
Sbjct: 319 ---RRPSPRRRTPPRRMPPPPRHRRSR 342


>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
          Length = 1192

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 43/160 (26%), Positives = 63/160 (39%), Gaps = 36/160 (22%)

Query: 274 PAKGNKSPSP-PDGSPAATPEIRVNHE----PEP---AGGATPGATLPKSPSQLRKGPPV 325
           P  G  SP P P G+P ++    ++      PEP   AGG  PG++ P   +  R+    
Sbjct: 122 PLSGGLSPDPKPGGAPTSSRRPLLSSPSWGGPEPEGRAGGGIPGSSSPHPGTGSRRLKVA 181

Query: 326 PPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQPAEASEVAG---------GTQPAA 376
           PPPP   P K                   +VTT    A   + AG         G     
Sbjct: 182 PPPPAPKPCK-------------------TVTTSGAKAGGGKGAGSRLSWPESEGKPRVK 222

Query: 377 GAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGA 416
           G++    T AS +A+++  A       A+ +G V  G+GA
Sbjct: 223 GSKSSAGTGASVSAAATAAAAGGGGSTASTSGGVGAGAGA 262


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.128    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,677,588
Number of Sequences: 37866
Number of extensions: 1227824
Number of successful extensions: 11908
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 147
Number of HSP's successfully gapped in prelim test: 1002
Number of HSP's that attempted gapping in prelim test: 8418
Number of HSP's gapped (non-prelim): 3569
length of query: 497
length of database: 18,247,518
effective HSP length: 106
effective length of query: 391
effective length of database: 14,233,722
effective search space: 5565385302
effective search space used: 5565385302
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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