Guide to the Human Genome
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Search of human proteins with 21536369

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21536369 TBP-associated factor 1C isoform 1 [Homo sapiens]
         (869 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21536369 TBP-associated factor 1C isoform 1 [Homo sapiens]        1799   0.0  
gi|21536367 TBP-associated factor 1C isoform 2 [Homo sapiens]        1578   0.0  
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap...    44   6e-04
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap...    44   6e-04
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       44   8e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    43   0.001
gi|239753975 PREDICTED: hypothetical protein [Homo sapiens]            42   0.003
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    41   0.005
gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo...    40   0.007
gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo ...    40   0.007
gi|239755589 PREDICTED: hypothetical protein [Homo sapiens]            40   0.009
gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo ...    39   0.016
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    39   0.016
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       39   0.021
gi|116284392 mucin 2 precursor [Homo sapiens]                          39   0.027
gi|153792074 proline rich 12 [Homo sapiens]                            39   0.027
gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]       38   0.036
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap...    38   0.036
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap...    38   0.036
gi|188536004 zinc finger protein 469 [Homo sapiens]                    37   0.061
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              37   0.061
gi|54860079 nadrin isoform 1 [Homo sapiens]                            37   0.061
gi|54860105 nadrin isoform 2 [Homo sapiens]                            37   0.061
gi|239582735 radial spoke head 4 homolog A isoform 2 [Homo sapiens]    37   0.079
gi|58219006 radial spoke head 4 homolog A isoform 1 [Homo sapiens]     37   0.079
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    37   0.079
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    37   0.079
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        37   0.10 
gi|113427525 PREDICTED: similar to hCG2037003 [Homo sapiens]           37   0.10 
gi|89941470 ankyrin repeat domain 34 [Homo sapiens]                    37   0.10 

>gi|21536369 TBP-associated factor 1C isoform 1 [Homo sapiens]
          Length = 869

 Score = 1799 bits (4659), Expect = 0.0
 Identities = 869/869 (100%), Positives = 869/869 (100%)

Query: 1   MDFPSSLRPALFLTGPLGLSDVPDLSFMCSWRDALTLPEAQPQNSENGALHVTKDLLWEP 60
           MDFPSSLRPALFLTGPLGLSDVPDLSFMCSWRDALTLPEAQPQNSENGALHVTKDLLWEP
Sbjct: 1   MDFPSSLRPALFLTGPLGLSDVPDLSFMCSWRDALTLPEAQPQNSENGALHVTKDLLWEP 60

Query: 61  ATPGPLPMLPPLIDPWDPGLTARDLLFRGGCRYRKRPRVVLDVTEQISRFLLDHGDVAFA 120
           ATPGPLPMLPPLIDPWDPGLTARDLLFRGGCRYRKRPRVVLDVTEQISRFLLDHGDVAFA
Sbjct: 61  ATPGPLPMLPPLIDPWDPGLTARDLLFRGGCRYRKRPRVVLDVTEQISRFLLDHGDVAFA 120

Query: 121 PLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGP 180
           PLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGP
Sbjct: 121 PLGKLMLENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGP 180

Query: 181 ILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDRL 240
           ILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDRL
Sbjct: 181 ILGTSVASHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDRL 240

Query: 241 HFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGESKALIYTFLPHWLTCYLTPGP 300
           HFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGESKALIYTFLPHWLTCYLTPGP
Sbjct: 241 HFQEVVLTPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGESKALIYTFLPHWLTCYLTPGP 300

Query: 301 FHPSSALLAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPGELAICSRSGA 360
           FHPSSALLAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPGELAICSRSGA
Sbjct: 301 FHPSSALLAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPGELAICSRSGA 360

Query: 361 VCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGCG 420
           VCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGCG
Sbjct: 361 VCLWSPEDGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGCG 420

Query: 421 LLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLKW 480
           LLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLKW
Sbjct: 421 LLLFRLGAEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLKW 480

Query: 481 NHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLAGEGASVPRLAGPPQSLPSRI 540
           NHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLAGEGASVPRLAGPPQSLPSRI
Sbjct: 481 NHGLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLAGEGASVPRLAGPPQSLPSRI 540

Query: 541 DSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQLR 600
           DSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQLR
Sbjct: 541 DSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQLR 600

Query: 601 PQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFTH 660
           PQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFTH
Sbjct: 601 PQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFTH 660

Query: 661 RQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSER 720
           RQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSER
Sbjct: 661 RQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSER 720

Query: 721 LGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEW 780
           LGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEW
Sbjct: 721 LGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEW 780

Query: 781 PPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQA 840
           PPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQA
Sbjct: 781 PPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQA 840

Query: 841 SSVRATRSQQHTPVLSSSQPLRKKPRMGF 869
           SSVRATRSQQHTPVLSSSQPLRKKPRMGF
Sbjct: 841 SSVRATRSQQHTPVLSSSQPLRKKPRMGF 869


>gi|21536367 TBP-associated factor 1C isoform 2 [Homo sapiens]
          Length = 775

 Score = 1578 bits (4086), Expect = 0.0
 Identities = 774/802 (96%), Positives = 775/802 (96%), Gaps = 27/802 (3%)

Query: 68  MLPPLIDPWDPGLTARDLLFRGGCRYRKRPRVVLDVTEQISRFLLDHGDVAFAPLGKLML 127
           MLPPLIDPWDPGLTARDLLFRGGCRYRKRPRVVLDVTEQISRFLLDHGDVAFAPLGKLML
Sbjct: 1   MLPPLIDPWDPGLTARDLLFRGGCRYRKRPRVVLDVTEQISRFLLDHGDVAFAPLGKLML 60

Query: 128 ENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGPILGTSVA 187
           ENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGPILGTSVA
Sbjct: 61  ENFKLEGAGSRTKKKTVVSVKKLLQDLGGHQPWGCPWAYLSNRQRRFSILGGPILGTSVA 120

Query: 188 SHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDRLHFQEVVL 247
           SHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDRLHFQEVVL
Sbjct: 121 SHLAELLHEELVLRWEQLLLDEACTGGALAWVPGRTPQFGQLVYPAGGAQDRLHFQEVVL 180

Query: 248 TPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGESKALIYTFLPHWLTCYLTPGPFHPSSAL 307
           TPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGE+                          L
Sbjct: 181 TPGDNPQFLGKPGRIQLQGPVRQVVTCTVQGET--------------------------L 214

Query: 308 LAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPGELAICSRSGAVCLWSPE 367
           LAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPGELAICSRSGAVCLWSPE
Sbjct: 215 LAVRSDYHCAVWKFGKQWQPTLLQAMQVEKGATGISLSPHLPGELAICSRSGAVCLWSPE 274

Query: 368 DGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGCGLLLFRLG 427
           DGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGCGLLLFRLG
Sbjct: 275 DGLRQIYRDPETLVFRDSSSWRWADFTAHPRVLTVGDRTGVKMLDTQGPPGCGLLLFRLG 334

Query: 428 AEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLKWNHGLPSP 487
           AEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLKWNHGLPSP
Sbjct: 335 AEASCQKGERVLLTQYLGHSSPKCLPPTLHLVCTQFSLYLVDERLPLVPMLKWNHGLPSP 394

Query: 488 LLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLAGEGASVPRLAGPPQSLPSRIDSLPAFP 547
           LLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLA EGASVPRLAGPPQSLPSRIDSLPAFP
Sbjct: 395 LLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLA-EGASVPRLAGPPQSLPSRIDSLPAFP 453

Query: 548 LLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQLRPQVDSSL 607
           LLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQLRPQVDSSL
Sbjct: 454 LLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFYQQLRPQVDSSL 513

Query: 608 RRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFTHRQMLGST 667
           RRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFTHRQMLGST
Sbjct: 514 RRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFTHRQMLGST 573

Query: 668 ELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSERLGEAWAG 727
           ELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSERLGEAWAG
Sbjct: 574 ELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSERLGEAWAG 633

Query: 728 RGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALP 787
           RGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALP
Sbjct: 634 RGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALP 693

Query: 788 LPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATR 847
           LPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATR
Sbjct: 694 LPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATR 753

Query: 848 SQQHTPVLSSSQPLRKKPRMGF 869
           SQQHTPVLSSSQPLRKKPRMGF
Sbjct: 754 SQQHTPVLSSSQPLRKKPRMGF 775


>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo
           sapiens]
          Length = 1758

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 46/166 (27%), Positives = 61/166 (36%), Gaps = 26/166 (15%)

Query: 673 EEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSERLGEAWAGRGAAW 732
           EE+G ++ VL      GQ LL   L  +P   P              R+  A  G G   
Sbjct: 460 EEKGYQVPVLGTPSLLGQSLLHGQL--IPTTGPV-------------RINTARPGGGRPG 504

Query: 733 WERQQ--GRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALPLPP 790
           WE     G    P +Q RR +R    S +     H + S+ T  P  P  P    +P PP
Sbjct: 505 WEHSNKLGYLVSPPQQIRRGERSCYRSINRGRH-HSERSQRTQGPSLPATPVFVPVPPPP 563

Query: 791 TTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPP 836
             PP     P     GVP  Q      +  + PP +  P   + PP
Sbjct: 564 LYPPPPHTLP--LPPGVPPPQ------FSPQFPPGQPPPAGYSVPP 601


>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo
           sapiens]
          Length = 1792

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 46/166 (27%), Positives = 61/166 (36%), Gaps = 26/166 (15%)

Query: 673 EEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSERLGEAWAGRGAAW 732
           EE+G ++ VL      GQ LL   L  +P   P              R+  A  G G   
Sbjct: 460 EEKGYQVPVLGTPSLLGQSLLHGQL--IPTTGPV-------------RINTARPGGGRPG 504

Query: 733 WERQQ--GRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALPLPP 790
           WE     G    P +Q RR +R    S +     H + S+ T  P  P  P    +P PP
Sbjct: 505 WEHSNKLGYLVSPPQQIRRGERSCYRSINRGRH-HSERSQRTQGPSLPATPVFVPVPPPP 563

Query: 791 TTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPP 836
             PP     P     GVP  Q      +  + PP +  P   + PP
Sbjct: 564 LYPPPPHTLP--LPPGVPPPQ------FSPQFPPGQPPPAGYSVPP 601


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 84/390 (21%), Positives = 136/390 (34%), Gaps = 54/390 (13%)

Query: 485 PSPLLLARLLPPPRPSCVQPLLLG------GQGGQLQLLHLAGEGA--SVPRLAGPPQSL 536
           PS    A +LPPP        LLG       Q   +++  L  EGA    P    PP   
Sbjct: 359 PSEEPPAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVE 418

Query: 537 PSRIDSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLVLFQLSAAGDVFY 596
            +  D  P  P   P+ + R    L+  T    A+  P   APT     FQ     +   
Sbjct: 419 ETLADVQPLLPEEAPREEAR---ELQLST----AMETPAEEAPTE----FQSPLPKETTA 467

Query: 597 QQLRPQVDSSLRRDAGPPGDTQP-DCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTA 655
           ++   ++   L     PP D  P +  +P +  TS + A       A ++ PLA      
Sbjct: 468 EEASAEIQ--LLAATEPPADETPAEARSPLSEETSAEEA------HAEVQSPLAEETTAE 519

Query: 656 PTFTHRQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLED 715
                 Q+L + E   +E   +    L +  +  +   +      P+A+     E+ LE 
Sbjct: 520 EASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQS---PSAKGVSIEEAPLE- 575

Query: 716 KLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSP 775
            L    GE                T+E      +    T+ S+       V P     +P
Sbjct: 576 -LQPPSGEE--------------TTAEEASAAIQLLAATEASAE-EAPAEVQPPPAEEAP 619

Query: 776 HSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTP 835
              + PPA+  P     PP++E   +   Q  P+E+         + PP  + P     P
Sbjct: 620 AEVQPPPAEEAPAEVQPPPAEEAPAE--VQPPPAEEAPA----EVQPPPAEEAPAEVQPP 673

Query: 836 PHSQASSVRATRSQQHTPVLSSSQPLRKKP 865
           P  +A +   +   + TP+  +   +   P
Sbjct: 674 PAEEAPAEVQSLPAEETPIEETLAAVHSPP 703


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 52/175 (29%), Positives = 64/175 (36%), Gaps = 25/175 (14%)

Query: 701 PAAEPPPAPESGLEDKLSERLGE--------AWAGRGAAWWERQQGRTSEP---GRQTRR 749
           PAA   P+   GL+   S  L          A +G  A    R     S+P   G Q  R
Sbjct: 213 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 272

Query: 750 PK-----RRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPA-DALPLPPTTPPSQELTP--- 800
           P      R+    +   LS     +   S+P SP  PP+   LP PP TPPSQ  T    
Sbjct: 273 PPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGS 332

Query: 801 ---DACAQGVPSEQRQMLRDYMAKLPPQRDTP--GCATTPPHSQASSVRATRSQQ 850
               A    +PS     L     + PP    P      +PP S   S  AT S Q
Sbjct: 333 PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ 387



 Score = 33.5 bits (75), Expect = 0.88
 Identities = 98/398 (24%), Positives = 123/398 (30%), Gaps = 56/398 (14%)

Query: 483 GLPSPLLLARLLPPPRPSCVQPLLLGGQGGQLQLLHLAGEGASVPRLAGPPQSLPSRIDS 542
           GLP P   AR    PRP    P        +      +      P   G  Q   SR  S
Sbjct: 179 GLPRPAPSAR----PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 234

Query: 543 LPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTP-GLVLFQLSAAGDVFYQQLRP 601
             A PL  P            P+       P  PS P P GL             Q LRP
Sbjct: 235 SSATPLSSPA--------RSGPSARGTPRAPAHPSQPKPKGL-------------QALRP 273

Query: 602 QVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFTHR 661
              +  R+DA P           T S ++  +      L+ L   P  PP     +    
Sbjct: 274 PQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS---- 329

Query: 662 QMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPA---------PESG 712
             LGS  L+          +   A    Q      L  L A   PPA         P   
Sbjct: 330 --LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ 387

Query: 713 LEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSG---HVDPS 769
             + L+  L +A      +     Q   S P      P       +  SL+     V PS
Sbjct: 388 APNALAVHLLQAPFSPPPS--PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 445

Query: 770 EDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLP-PQRDT 828
              S P SP   P      PP  PP     P   A+  P     +    +  LP P    
Sbjct: 446 PPASPPMSPSATP------PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASF 499

Query: 829 PGCAT-TPPHSQASSVRATRSQQHTPVLSSSQPLRKKP 865
           PG A  +P  S   S  AT   Q  PVL++  PL + P
Sbjct: 500 PGQAPFSPSASLPMSPLATPPPQAPPVLAA--PLLQVP 535


>gi|239753975 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 389

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 31/98 (31%), Positives = 43/98 (43%), Gaps = 4/98 (4%)

Query: 767 DPSEDTSSPHSPEWPPADALPLPPT--TPPSQELTPDACAQGVPSEQRQMLRDYMAKLPP 824
           DP+   SSPH+P  PP  A+   P+  TP S+ L P +  +G P       R+  A  P 
Sbjct: 107 DPAAPPSSPHAPTRPPPQAVQPRPSEPTPGSEALPPGSLPEGEPRPYALPPRESPAPRPF 166

Query: 825 QRDTPGCATTPPHSQASSVRATRSQQHTPVLSSSQPLR 862
           +   P  +  PP  Q  S R        P   S +P+R
Sbjct: 167 RWGDP-FSPAPPRPQPPS-RPAAQPPSRPAFRSPRPVR 202


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 95/368 (25%), Positives = 129/368 (35%), Gaps = 76/368 (20%)

Query: 532 PPQSLPSRIDSLPAF------PLLEPKIQWRLQERLKAP---TIGLAAVVPPLPSAPTPG 582
           PPQ  P R D+ PA       PL  P         +  P      L A +PP P   TP 
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATP- 340

Query: 583 LVLFQLSAAGDVFYQQLRPQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKA 642
           L L   S +     Q L P   ++    A PP  T P   AP +  T             
Sbjct: 341 LPLAPPSPSAPPSLQTL-PSPPATPPSQA-PPSMTTPPMQAPPSLQTIPPIQVPHSLTSP 398

Query: 643 LLKVPLAPPVWTAPTFTHRQMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPA 702
            L+ P +P   ++   T    LGS  L+               M+  Q        S PA
Sbjct: 399 SLQAPPSPLALSSLQAT--TSLGSPTLQATHS--------FLTMSPRQTQASLTSPSRPA 448

Query: 703 AEPPPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSL 762
           + PP +P   L+  LS                      + P  QT      + LSS  ++
Sbjct: 449 STPPDSPP--LQAPLS--------------------LPASPPLQTSLSPAVSPLSSPLTI 486

Query: 763 SGHVDPSEDTSSPHSPEWPPADALPLPP------------TTPPSQELTPDACAQGVPSE 810
             H   +  + + HSP+  P  +L +PP             TPP+   TP    + +PS 
Sbjct: 487 --HPLQALSSLASHSPQ-APLSSLIMPPLETQSSLAPPSLQTPPASLTTPP--LENLPSL 541

Query: 811 QRQMLRDYMAKL-PPQRDTPGC------------ATTPPHSQASSVRATRSQQHTPVLSS 857
               L+   A L  P  +TP C             TTPP    SS+ AT   Q  P L +
Sbjct: 542 APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI-ATPPPQAPPAL-A 599

Query: 858 SQPLRKKP 865
           S PL+  P
Sbjct: 600 SPPLQGLP 607



 Score = 38.1 bits (87), Expect = 0.036
 Identities = 54/182 (29%), Positives = 65/182 (35%), Gaps = 33/182 (18%)

Query: 701 PAAEPPPAPESGLEDKLSERLGE--------AWAGRGAAWWERQQGRTSEP---GRQTRR 749
           PAA   P+   GL+   S  L          A +G  A    R     S+P   G Q  R
Sbjct: 222 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281

Query: 750 PK-----RRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPAD--ALPLPPTTPPSQEL-TPD 801
           P      R+    +   LS     +   S   +   PP D  A PLP T PPS  L TP 
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPL 341

Query: 802 ACAQGVPSEQRQMLRDYMAKLPPQRDT-PGCATTPPHSQASSVRATRSQQHTPVLSSSQP 860
             A   PS             PP   T P    TPP SQA     T   Q  P L +  P
Sbjct: 342 PLAPPSPS------------APPSLQTLPSPPATPP-SQAPPSMTTPPMQAPPSLQTIPP 388

Query: 861 LR 862
           ++
Sbjct: 389 IQ 390



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 91/401 (22%), Positives = 121/401 (30%), Gaps = 64/401 (15%)

Query: 495 PPPRPSCVQPLLLGGQGGQLQLLHLAGEGASVPRLAGPPQSLPSRIDSLPAFPL---LEP 551
           PP  P    PL L         L  A    S P    P Q+L S     P  PL   + P
Sbjct: 451 PPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMP 510

Query: 552 KIQWRLQERLKAPTIGL---AAVVPPLPSAPTPGLVLFQLSAAGDVFYQQLRPQVDSSLR 608
            ++   Q  L  P++     +   PPL + P+      Q ++A         P   +   
Sbjct: 511 PLE--TQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568

Query: 609 RDAGPPGDTQPDCHAPTASWTSQDTAG---CSQWLKALLKVPLAPPVWTAPTFTHRQMLG 665
             A P   T P    P++  T    A     S  L+ L   PL+P     P       L 
Sbjct: 569 LQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALP 628

Query: 666 STELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAPESGLEDKLSERLGEAW 725
             +          L  L     +    L   L   P + PP  P                
Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV--------------- 673

Query: 726 AGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSG---HVDPSEDTSSPHSPEWPP 782
                      Q   S P      P       +  SL+     V PS   S P SP   P
Sbjct: 674 -----------QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 722

Query: 783 ---------ADALPLPPTTPPSQELTPDAC-------------AQGVPSEQRQMLRDYMA 820
                    A  L +PP+ P S  ++P A               Q  PS    +    +A
Sbjct: 723 PPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLA 782

Query: 821 KLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSSQPL 861
           K PPQ   P    TPP     S  A+   Q     S+S P+
Sbjct: 783 KPPPQ--APPALATPPLQALPSPPASFPGQAPFSPSASLPM 821



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 26/94 (27%), Positives = 38/94 (40%), Gaps = 3/94 (3%)

Query: 774 SPHSPEWPPA-DALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCA 832
           +P SP  PP+   LP PP TPPSQ   P +           +      ++P    +P   
Sbjct: 344 APPSPSAPPSLQTLPSPPATPPSQ--APPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQ 401

Query: 833 TTPPHSQASSVRATRSQQHTPVLSSSQPLRKKPR 866
             P     SS++AT S     + ++   L   PR
Sbjct: 402 APPSPLALSSLQATTSLGSPTLQATHSFLTMSPR 435



 Score = 31.2 bits (69), Expect = 4.4
 Identities = 35/108 (32%), Positives = 43/108 (39%), Gaps = 16/108 (14%)

Query: 768 PSEDTSSPHSPEWPPADALPLPPTTPPSQELTPDACA----QGVPSEQRQMLRDYMAKLP 823
           PS    +P SP   PA     P  TPPSQ   P + A    Q  PS          A  P
Sbjct: 669 PSPPVQAPFSP---PASPPVSPSATPPSQ--APPSLAAPPLQVPPSPPASPPMSPSATPP 723

Query: 824 PQRDTPGCA------TTPPHSQASSVRATRSQQHTPVLSSSQPLRKKP 865
           PQ   P  A       +PP S   S  AT   +  P+L ++ PL+  P
Sbjct: 724 PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLL-AAPPLQVPP 770



 Score = 30.0 bits (66), Expect = 9.7
 Identities = 36/123 (29%), Positives = 49/123 (39%), Gaps = 12/123 (9%)

Query: 750 PKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALP---LPPTTPPSQELTPDACAQG 806
           P +     +S  L G   P     +   P+ PP  ALP    PP+ P S  L+P A    
Sbjct: 591 PPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLA---- 646

Query: 807 VPSEQR-QMLRDYMAKL---PPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSSQPLR 862
            PS Q    L  ++ +    PP         +PP S   S  AT   Q  P L ++ PL+
Sbjct: 647 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL-AAPPLQ 705

Query: 863 KKP 865
             P
Sbjct: 706 VPP 708


>gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo
           sapiens]
          Length = 1198

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 49/197 (24%), Positives = 81/197 (41%), Gaps = 31/197 (15%)

Query: 662 QMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAP--ESGLEDKLSE 719
           + L + E   +E++ +    L + +A+ Q L         AA PP +   E+  ++K   
Sbjct: 641 ECLFTLEAHSQEQKKRVCWCLSENIAKQQQL---------AASPPDSKMFETEADEKREM 691

Query: 720 RLGEAWAGRGAAWWERQQGRTSEPGRQTR----------RPKRRTQLSSSFSLSGHVDPS 769
            L E   G+G    +    +   PG++             P  +    S   LS   D +
Sbjct: 692 ALEE---GKGPGAEDSPPSKEPSPGQELPPGQDLPPNKDSPSGQEPAPSQEPLSSK-DSA 747

Query: 770 EDTSSPHSPEWPPADALPLPPTTPPSQELTP----DACAQGVPSEQRQMLRDYMA-KLPP 824
               SP  P+ PP+  +P     PP+Q+L+P     A  + +P +   + +D  A +  P
Sbjct: 748 TSEGSPPGPDAPPSKDVPPCQEPPPAQDLSPCQDLPAGQEPLPHQDPLLTKDLPAIQESP 807

Query: 825 QRDTPGCATTPPHSQAS 841
            RD P C   PP SQ S
Sbjct: 808 TRDLPPCQDLPP-SQVS 823


>gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo
           sapiens]
          Length = 917

 Score = 40.4 bits (93), Expect = 0.007
 Identities = 49/197 (24%), Positives = 81/197 (41%), Gaps = 31/197 (15%)

Query: 662 QMLGSTELRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPPAP--ESGLEDKLSE 719
           + L + E   +E++ +    L + +A+ Q L         AA PP +   E+  ++K   
Sbjct: 360 ECLFTLEAHSQEQKKRVCWCLSENIAKQQQL---------AASPPDSKMFETEADEKREM 410

Query: 720 RLGEAWAGRGAAWWERQQGRTSEPGRQTR----------RPKRRTQLSSSFSLSGHVDPS 769
            L E   G+G    +    +   PG++             P  +    S   LS   D +
Sbjct: 411 ALEE---GKGPGAEDSPPSKEPSPGQELPPGQDLPPNKDSPSGQEPAPSQEPLSSK-DSA 466

Query: 770 EDTSSPHSPEWPPADALPLPPTTPPSQELTP----DACAQGVPSEQRQMLRDYMA-KLPP 824
               SP  P+ PP+  +P     PP+Q+L+P     A  + +P +   + +D  A +  P
Sbjct: 467 TSEGSPPGPDAPPSKDVPPCQEPPPAQDLSPCQDLPAGQEPLPHQDPLLTKDLPAIQESP 526

Query: 825 QRDTPGCATTPPHSQAS 841
            RD P C   PP SQ S
Sbjct: 527 TRDLPPCQDLPP-SQVS 542


>gi|239755589 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 356

 Score = 40.0 bits (92), Expect = 0.009
 Identities = 52/188 (27%), Positives = 71/188 (37%), Gaps = 32/188 (17%)

Query: 628 WTSQDTAGCSQWLKALLKVPLAPPVWTAPTFTHR--QMLGSTELRREEEEGQRLGVLRKA 685
           W +Q   G  +   AL      P V+T  +  H   +   S      E EG R G     
Sbjct: 123 WGTQAPCGRLRAKPALQTQRKEPLVFTQRSLLHSSPRWFSSRHSSISEGEGDRCG----- 177

Query: 686 MARGQLLLQRDLGSLPAAEP-PPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPG 744
                   +   GS P A P PP P+ G     ++R  EA     ++W       T+ PG
Sbjct: 178 ------FAEPPGGSSPPAPPLPPPPKPGSP---TQRAREA-----SSWKPPGHSHTAPPG 223

Query: 745 RQTRRP-KRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELTPDAC 803
           R T+RP  +R    SS  LS    P    +S  S    P   LP PP   P+        
Sbjct: 224 RGTQRPLTQRHSSESSSELSSSAWPGTIWTSTLS----PGQRLPTPPPPDPAA-----LT 274

Query: 804 AQGVPSEQ 811
           + G+P +Q
Sbjct: 275 SWGLPQQQ 282


>gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo
           sapiens]
          Length = 519

 Score = 39.3 bits (90), Expect = 0.016
 Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 6/80 (7%)

Query: 767 DPSEDTSSPHSPEWPPADALPLPPTTPPSQELTP----DACAQGVPSEQRQMLRDYMA-K 821
           D +    SP  P+ PP+  +P     PP+Q+L+P     A  + +P +   + +D  A +
Sbjct: 66  DSATSEGSPPGPDAPPSKDVPPCQEPPPAQDLSPCQDLPAGQEPLPHQDPLLTKDLPAIQ 125

Query: 822 LPPQRDTPGCATTPPHSQAS 841
             P RD P C   PP SQ S
Sbjct: 126 ESPTRDLPPCQDLPP-SQVS 144


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 39.3 bits (90), Expect = 0.016
 Identities = 96/380 (25%), Positives = 133/380 (35%), Gaps = 70/380 (18%)

Query: 486  SPLLLARLLPPPRPSCVQ---PLLL-GGQGGQLQLLHLAG-------------EGASVPR 528
            S LLL +  P P+PS +Q   PL L G Q  Q+ LLH AG             E +SVP 
Sbjct: 4073 SQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPH 4132

Query: 529  -LAGPPQSLPSRIDSL------PAFPLLEPKIQWRL--QERLKAPTIGLAAVVPPLPSAP 579
             LA P  SL  +  S+      P  P+LE  +Q     Q     P +     +P +   P
Sbjct: 4133 LLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMP 4192

Query: 580  TPGLVLFQLSA--AGDVFYQQLRPQVDSSLR--------RDAGPPGDTQPDCHAPTASWT 629
            T G +  QL    A +   + L PQ    L+        + +     T P     T +  
Sbjct: 4193 TVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSP 4252

Query: 630  SQDTAGCSQWLKALLKVPLAPPVWTAPTFTHRQMLGSTELRREEEEGQRLGVLRKAMARG 689
             Q   GC   L         P   T P     Q LG+       +   RL     A++ G
Sbjct: 4253 LQGLLGCQPQLGGF------PGPQTGPL----QELGAGP---RPQGPPRLPAPPGALSTG 4299

Query: 690  QLLLQRDLGSLPAAEPPPAPE-----SGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPG 744
             +     LG +    PP +P+     S L    S+   EA          + QG T EP 
Sbjct: 4300 PV-----LGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPP 4354

Query: 745  RQTRRPKRRTQLSSSFSLS-GHVDPSEDTSSPHSPEWPP----------ADALPLPPTTP 793
                 P       + FS   G  DP ++ +    PE                +P      
Sbjct: 4355 PGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLS 4414

Query: 794  PSQELTPDACAQGVPSEQRQ 813
              QE   + CA G  S +R+
Sbjct: 4415 IKQEPREEPCALGAQSVKRE 4434



 Score = 31.6 bits (70), Expect = 3.3
 Identities = 45/190 (23%), Positives = 64/190 (33%), Gaps = 27/190 (14%)

Query: 699  SLPAAEPPPAPES--GLEDKLSERLGEAWAGRGA---AWWERQQGRTSEPGRQTRRPK-- 751
            S P   PPP  ES   LE K  E LG +    G     + +     T   G + + P   
Sbjct: 2269 SEPLLSPPPFGESRKALEVK-KEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVF 2327

Query: 752  ------RRTQL---SSSFSLSGHVDPSEDTSSPHSPEWPP-------ADALPLPPTTPPS 795
                  R +Q+   S    L     P     +P  P  P         D    PP TP  
Sbjct: 2328 KAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRP 2387

Query: 796  QELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVL 855
            Q   P++C    P   R +  D  +++P    +   + +P   +  S  A      TP  
Sbjct: 2388 QPPPPESCCALPP---RSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRF 2444

Query: 856  SSSQPLRKKP 865
             S  P  + P
Sbjct: 2445 QSPDPYSRPP 2454


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 38.9 bits (89), Expect = 0.021
 Identities = 31/91 (34%), Positives = 33/91 (36%), Gaps = 6/91 (6%)

Query: 768  PSEDTSSPHSP-----EWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKL 822
            P++   SPH         PP  ALP  PT PP   L P       P    Q  R     L
Sbjct: 921  PTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVL 980

Query: 823  PPQRDTPGCATTPPHSQASSVRATRSQQHTP 853
            PPQ   P     PP   A  VR    Q H P
Sbjct: 981  PPQPMLPPQPVLPP-QPALPVRPEPLQPHLP 1010


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 38.5 bits (88), Expect = 0.027
 Identities = 36/136 (26%), Positives = 47/136 (34%), Gaps = 10/136 (7%)

Query: 740  TSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHS--PEWPPADALPLPPTTPPSQE 797
            T+ P   T  P   T   S  + +    P   T SP +  P  PPA    LPPTT PS  
Sbjct: 1467 TTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPP 1526

Query: 798  LT-----PDACAQGVPSEQRQMLRDYMAKLPP---QRDTPGCATTPPHSQASSVRATRSQ 849
             T     P       P+            LPP       P   TTPP +   S   T + 
Sbjct: 1527 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTP 1586

Query: 850  QHTPVLSSSQPLRKKP 865
                + +++ P    P
Sbjct: 1587 SPPTITTTTPPPTTTP 1602



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 32/119 (26%), Positives = 39/119 (32%), Gaps = 6/119 (5%)

Query: 741  SEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHS-PEWPPADALPLPPTTPPSQELT 799
            S P   T  P   T  S   + +    P+   S P + P  PP     LPPTT PS   T
Sbjct: 1587 SPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPT 1646

Query: 800  -----PDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTP 853
                 P       P+             PP   TP    T   S  ++   T S   TP
Sbjct: 1647 TTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTP 1705



 Score = 30.4 bits (67), Expect = 7.4
 Identities = 28/97 (28%), Positives = 34/97 (35%), Gaps = 26/97 (26%)

Query: 768  PSEDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRD 827
            PS  T++P SP  PP     LPPTT PS   T                       PP   
Sbjct: 1399 PSPPTTTP-SP--PPTSTTTLPPTTTPSPPTT-------------------TTTTPPPTT 1436

Query: 828  TPG----CATTPPHSQASSVRATRSQQHTPVLSSSQP 860
            TP       TTPP +   S   + +    P  + S P
Sbjct: 1437 TPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPP 1473



 Score = 30.4 bits (67), Expect = 7.4
 Identities = 29/103 (28%), Positives = 35/103 (33%), Gaps = 13/103 (12%)

Query: 741  SEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEW-PPADALPLPPTTPPSQELT 799
            S P   T  P   T  S   + +    P+   S P S    PP    P PPTT PS    
Sbjct: 1423 SPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPS---- 1478

Query: 800  PDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASS 842
            P       P+             PP   TP   TT P +  +S
Sbjct: 1479 PPTTTPSPPTT--------TTTTPPPTTTPSPPTTTPITPPAS 1513


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 38.5 bits (88), Expect = 0.027
 Identities = 30/89 (33%), Positives = 39/89 (43%), Gaps = 10/89 (11%)

Query: 752  RRTQLSSSFSLSGHVDPS----EDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGV 807
            R  Q S S ++S   DP     +DTS+P  P   PA A+P PP  P      P A + G 
Sbjct: 1392 RDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPG----LPSANSNGT 1447

Query: 808  PSEQRQMLRDYMAKLPPQRDTPGCATTPP 836
            P  +  +L +     PP   TP     PP
Sbjct: 1448 P--EPPLLEEKPPPTPPPAPTPQPQPPPP 1474



 Score = 30.4 bits (67), Expect = 7.4
 Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 6/96 (6%)

Query: 770  EDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTP 829
            E T+S   PE  P  A+P PP       L P         ++++ +      L  +R T 
Sbjct: 1707 EKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVE-----KEKEKEKVTRGERPLRGERATS 1761

Query: 830  GCATTPPHSQASSVRAT-RSQQHTPVLSSSQPLRKK 864
            G  T P  S A+   AT R  +  P    ++P  KK
Sbjct: 1762 GRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKK 1797


>gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]
          Length = 1243

 Score = 38.1 bits (87), Expect = 0.036
 Identities = 35/117 (29%), Positives = 47/117 (40%), Gaps = 16/117 (13%)

Query: 756  LSSSFSLS------GHVDPSEDTSSPHSPEWP-PADALPLPPTTPPSQELTPDACAQGVP 808
            L+S+FSL+        + PS    S   P  P P  +LPLPP   P  + +P      V 
Sbjct: 926  LASAFSLAVMTVAQSLLSPSPGLLSQSPPAPPSPLPSLPLPPPVAPGGQESPSPHTAEVE 985

Query: 809  SEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSSQPLRKKP 865
            SE         A  PP R  PG A   P S+    +     Q T     ++PL  +P
Sbjct: 986  SE---------ASPPPARPLPGEARLAPISEEGKPQLVGRFQVTSSKEPAEPLPLQP 1033


>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sapiens]
          Length = 2603

 Score = 38.1 bits (87), Expect = 0.036
 Identities = 42/169 (24%), Positives = 59/169 (34%), Gaps = 36/169 (21%)

Query: 699  SLPAAEPPPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSS 758
            S P++  PPA   G+        G A   + A+  E++ G  S P  +T   +     SS
Sbjct: 2041 SSPSSPSPPAQPGGVSRNSPLDCGSASPNKVASSSEQEAG--SPPVVETTNTRPPNSSSS 2098

Query: 759  SFSLSGHVDPSEDTSSPHSPEWPPADALPLPP-----TTPP------------------S 795
            S S S H +  +   S      PP     +PP     T PP                   
Sbjct: 2099 SGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPVAVPSTAPVTYP 2158

Query: 796  QELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVR 844
               TP  C Q  P  +   +R      PP        TT PH  ++SV+
Sbjct: 2159 MPQTPMGCPQPTPKMETPAIRP-----PPH------GTTAPHKNSASVQ 2196


>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sapiens]
          Length = 2352

 Score = 38.1 bits (87), Expect = 0.036
 Identities = 42/169 (24%), Positives = 59/169 (34%), Gaps = 36/169 (21%)

Query: 699  SLPAAEPPPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSS 758
            S P++  PPA   G+        G A   + A+  E++ G  S P  +T   +     SS
Sbjct: 1790 SSPSSPSPPAQPGGVSRNSPLDCGSASPNKVASSSEQEAG--SPPVVETTNTRPPNSSSS 1847

Query: 759  SFSLSGHVDPSEDTSSPHSPEWPPADALPLPP-----TTPP------------------S 795
            S S S H +  +   S      PP     +PP     T PP                   
Sbjct: 1848 SGSSSAHSNQQQPPGSVSQEPRPPLQQSQVPPPEVRMTVPPLATSSAPVAVPSTAPVTYP 1907

Query: 796  QELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVR 844
               TP  C Q  P  +   +R      PP        TT PH  ++SV+
Sbjct: 1908 MPQTPMGCPQPTPKMETPAIRP-----PPH------GTTAPHKNSASVQ 1945


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 37.4 bits (85), Expect = 0.061
 Identities = 36/116 (31%), Positives = 49/116 (42%), Gaps = 12/116 (10%)

Query: 750 PKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPP-ADALPLPPTTPPSQELTPDACAQGVP 808
           P  R + +   +++G + P +  SSP  P  PP  D  P   TT  ++E    A A  +P
Sbjct: 2   PGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELP 61

Query: 809 SEQRQMLRDYMAKLPPQR-----DTP---GCATTPPHS---QASSVRATRSQQHTP 853
             Q +  RD   K P  R      TP   G   TPP     QA S  A R++   P
Sbjct: 62  EAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPP 117



 Score = 34.3 bits (77), Expect = 0.51
 Identities = 32/109 (29%), Positives = 46/109 (42%), Gaps = 10/109 (9%)

Query: 708  APESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVD 767
            A E+G +    +R+       GAA  E+  G+     R    P R T+       SG  +
Sbjct: 2688 AGETGAQKPPGDRMLCPGRMDGAALGEQPTGQKGASARGFWGP-RETKALGVCKESGS-E 2745

Query: 768  PSEDTSSPHSPE----W----PPADALPLPPTTPPSQELTPDACAQGVP 808
            P+ED+S  HS      W    PP   L  P T+    + T  +C QG+P
Sbjct: 2746 PAEDSSRAHSRSEEGVWEENTPPLGPLGFPETSSSPADSTTSSCLQGLP 2794



 Score = 31.6 bits (70), Expect = 3.3
 Identities = 39/159 (24%), Positives = 61/159 (38%), Gaps = 25/159 (15%)

Query: 688  RGQLLLQRDLGSLPAAEPPPAPESGLEDKLSE----------RLGEAWAGRGAAWWERQQ 737
            RGQ   +R LG LP      +  + L + ++E            G+A    G  W +  +
Sbjct: 3176 RGQA--RRSLGDLPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSPGDPWGQEGE 3233

Query: 738  GRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQE 797
             +   PG +  +P+ R+  S+     G   P   +++  +    P      PP T PS  
Sbjct: 3234 AKKDSPGERA-KPRARSTPSNP---DGAATPDSASATALADAGSPG-----PPRTTPSP- 3283

Query: 798  LTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPP 836
             +PD  A G P  Q   + +  A   P RD   C    P
Sbjct: 3284 -SPDPWAGGEPLLQATPVHE--ACKDPSRDCHHCGKRFP 3319


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 37.4 bits (85), Expect = 0.061
 Identities = 47/180 (26%), Positives = 69/180 (38%), Gaps = 26/180 (14%)

Query: 670 RREEEEGQRLGVLRKAMARGQLL------------LQRDLGSLPAAEPPPAPESGLEDKL 717
           RR EEE +R+   R+A    +L             L+ +  + PAA   PAP   +  +L
Sbjct: 469 RRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKEL 528

Query: 718 SERLGEAWAGRGAAWWERQQGRTSEPGRQTRRP---KRRTQLSSSFSLSGHVDPSEDTSS 774
                   A       E ++   + P + T  P      T +S   S S     S + +S
Sbjct: 529 PAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFE-AS 587

Query: 775 PHSPEWP------PADALPLPPTTPPSQELTPDACAQG---VPSEQRQMLRDYMAKLPPQ 825
           P  P+ P      P + +P PPTTPP  ++ P     G    P  Q      Y   LPP+
Sbjct: 588 PVEPQLPSKEGPEPPEEVP-PPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPR 646



 Score = 30.8 bits (68), Expect = 5.7
 Identities = 44/187 (23%), Positives = 63/187 (33%), Gaps = 39/187 (20%)

Query: 701 PAAEPPPAPESGLE--DKLSERLGEAWAG--RGAAWWERQQGRTSEPGRQTRRPKRRTQL 756
           P   P    E  L+  D+L +   + WAG      + E+ +    E GR +         
Sbjct: 300 PVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHR 359

Query: 757 SSSFSLSGHVDPSEDT----SSPHS---------------PEWPPADALPLPPTTPPSQE 797
            S  S SG   P E      +SP+S               PE  P    P PP  PP + 
Sbjct: 360 DSQ-SASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHR- 417

Query: 798 LTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSS 857
               A   G P        DY     P R  P C    P  +  + R  R Q  + +  +
Sbjct: 418 --GPAGNWGPPG-------DY-----PDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLA 463

Query: 858 SQPLRKK 864
            +  R++
Sbjct: 464 VERARRR 470


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 37.4 bits (85), Expect = 0.061
 Identities = 41/136 (30%), Positives = 58/136 (42%), Gaps = 19/136 (13%)

Query: 740 TSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELT 799
           T   G+   +P   +QLS+    S  + P +  +  H P  PP  A PL  T P SQ   
Sbjct: 679 TQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPN--HPPPQPPTQATPLMHTKPNSQG-P 735

Query: 800 PDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATR---------SQQ 850
           P+  A  +PSE      +  +  PPQ  TP  +T P   Q  S+ A +         +Q 
Sbjct: 736 PNPMA--LPSEHG---LEQPSHTPPQTPTPP-STPPLGKQNPSLPAPQTLAGGNPETAQP 789

Query: 851 HTPVLSSSQPLRKKPR 866
           H   L   +P+  KPR
Sbjct: 790 HAGTLPRPRPV-PKPR 804


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score = 37.4 bits (85), Expect = 0.061
 Identities = 41/136 (30%), Positives = 58/136 (42%), Gaps = 19/136 (13%)

Query: 740 TSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELT 799
           T   G+   +P   +QLS+    S  + P +  +  H P  PP  A PL  T P SQ   
Sbjct: 601 TQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPN--HPPPQPPTQATPLMHTKPNSQG-P 657

Query: 800 PDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATR---------SQQ 850
           P+  A  +PSE      +  +  PPQ  TP  +T P   Q  S+ A +         +Q 
Sbjct: 658 PNPMA--LPSEHG---LEQPSHTPPQTPTPP-STPPLGKQNPSLPAPQTLAGGNPETAQP 711

Query: 851 HTPVLSSSQPLRKKPR 866
           H   L   +P+  KPR
Sbjct: 712 HAGTLPRPRPV-PKPR 726


>gi|239582735 radial spoke head 4 homolog A isoform 2 [Homo sapiens]
          Length = 600

 Score = 37.0 bits (84), Expect = 0.079
 Identities = 43/162 (26%), Positives = 62/162 (38%), Gaps = 31/162 (19%)

Query: 714 EDKLSERLGEA---WAGRGAAWWERQQGRTSEP---------GRQTRRPKR-RTQLSSSF 760
           E +  E LGE    W G+ AA  +  +  +SEP         GRQ+R  +    Q  +  
Sbjct: 10  EKENQEELGETRRPWEGKTAASPQYSEPESSEPLEAKQGPETGRQSRSSRPWSPQSRAKT 69

Query: 761 SLSGHVDPSEDTSSPHSPEWPPADALPLPP-----TTPPSQELTPDACAQ-GVPSEQRQM 814
            L G   P   + +P SP  P +   PL P       PP  + T     + G P      
Sbjct: 70  PLGGPAGPETSSPAPVSPREPSSSPSPLAPARQDLAAPPQSDRTTSVIPEAGTPYPD--- 126

Query: 815 LRDYMAKLPPQRDTPGCATTPPH-SQASSVRATRSQQHTPVL 855
                   P ++ +    +TP H SQ+      +SQQ  P L
Sbjct: 127 --------PLEQSSDKRESTPHHTSQSEGNTFQQSQQPKPHL 160


>gi|58219006 radial spoke head 4 homolog A isoform 1 [Homo sapiens]
          Length = 716

 Score = 37.0 bits (84), Expect = 0.079
 Identities = 43/162 (26%), Positives = 62/162 (38%), Gaps = 31/162 (19%)

Query: 714 EDKLSERLGEA---WAGRGAAWWERQQGRTSEP---------GRQTRRPKR-RTQLSSSF 760
           E +  E LGE    W G+ AA  +  +  +SEP         GRQ+R  +    Q  +  
Sbjct: 10  EKENQEELGETRRPWEGKTAASPQYSEPESSEPLEAKQGPETGRQSRSSRPWSPQSRAKT 69

Query: 761 SLSGHVDPSEDTSSPHSPEWPPADALPLPP-----TTPPSQELTPDACAQ-GVPSEQRQM 814
            L G   P   + +P SP  P +   PL P       PP  + T     + G P      
Sbjct: 70  PLGGPAGPETSSPAPVSPREPSSSPSPLAPARQDLAAPPQSDRTTSVIPEAGTPYPD--- 126

Query: 815 LRDYMAKLPPQRDTPGCATTPPH-SQASSVRATRSQQHTPVL 855
                   P ++ +    +TP H SQ+      +SQQ  P L
Sbjct: 127 --------PLEQSSDKRESTPHHTSQSEGNTFQQSQQPKPHL 160


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 37.0 bits (84), Expect = 0.079
 Identities = 51/190 (26%), Positives = 64/190 (33%), Gaps = 26/190 (13%)

Query: 696 DLGSLPAAEPPPAPESGLEDKLS-ERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPK--- 751
           D+GS P + PPP P +    + S    G      G    +   G T  P    R      
Sbjct: 175 DVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPR--QPSPGPTPPPFPGNRGTALGG 232

Query: 752 ---RRTQLSSSFSLSGHVD----PSEDTSSPHSPEWPPADALP------LPPTTPPSQEL 798
              R++ LSSS   S        PS        P  PP    P      +PP  PP Q  
Sbjct: 233 GSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPP--PPPQNN 290

Query: 799 TPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSS 858
            P      VPS  R          PP    PG    PP S  +       Q++  + SS+
Sbjct: 291 KPP-----VPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSST 345

Query: 859 QPLRKKPRMG 868
            PL    R G
Sbjct: 346 PPLPSPGRSG 355



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 29/102 (28%), Positives = 36/102 (35%), Gaps = 11/102 (10%)

Query: 748 RRPKRRTQLSSSF------SLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELTPD 801
           R P+R   LSSS         SG + P      P     PP  + PLPP  P S+  +  
Sbjct: 333 RLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTS 392

Query: 802 ACAQGVPSEQRQMLRDY-----MAKLPPQRDTPGCATTPPHS 838
                 P    +   D         LPP R + G    PP S
Sbjct: 393 RALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPS 434


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 37.0 bits (84), Expect = 0.079
 Identities = 51/190 (26%), Positives = 64/190 (33%), Gaps = 26/190 (13%)

Query: 696 DLGSLPAAEPPPAPESGLEDKLS-ERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPK--- 751
           D+GS P + PPP P +    + S    G      G    +   G T  P    R      
Sbjct: 175 DVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPR--QPSPGPTPPPFPGNRGTALGG 232

Query: 752 ---RRTQLSSSFSLSGHVD----PSEDTSSPHSPEWPPADALP------LPPTTPPSQEL 798
              R++ LSSS   S        PS        P  PP    P      +PP  PP Q  
Sbjct: 233 GSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPP--PPPQNN 290

Query: 799 TPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVLSSS 858
            P      VPS  R          PP    PG    PP S  +       Q++  + SS+
Sbjct: 291 KPP-----VPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSST 345

Query: 859 QPLRKKPRMG 868
            PL    R G
Sbjct: 346 PPLPSPGRSG 355



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 29/102 (28%), Positives = 36/102 (35%), Gaps = 11/102 (10%)

Query: 748 RRPKRRTQLSSSF------SLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELTPD 801
           R P+R   LSSS         SG + P      P     PP  + PLPP  P S+  +  
Sbjct: 333 RLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTS 392

Query: 802 ACAQGVPSEQRQMLRDY-----MAKLPPQRDTPGCATTPPHS 838
                 P    +   D         LPP R + G    PP S
Sbjct: 393 RALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPS 434


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 36.6 bits (83), Expect = 0.10
 Identities = 33/114 (28%), Positives = 49/114 (42%), Gaps = 4/114 (3%)

Query: 740  TSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELT 799
            TS     T +P  RT  S + ++S   +P  +++ P +PE PP+ +   P T  P+   T
Sbjct: 1336 TSTDQPVTPKPTSRTTRSRT-NMSSVKNP--ESTVPIAPELPPSTSTEQPVTPEPTSRAT 1392

Query: 800  PDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTP 853
                 +    +  + L     KL P   T    T  P SQA+  R  RS   TP
Sbjct: 1393 RGRKNRS-SGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTP 1445



 Score = 33.5 bits (75), Expect = 0.88
 Identities = 32/103 (31%), Positives = 44/103 (42%), Gaps = 11/103 (10%)

Query: 528  RLAGPPQSLPSRIDSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAP----TP-- 581
            R AG P SL + ID  P    LEPK Q    +R  A     +    P P++P    TP  
Sbjct: 1725 RAAGNPGSLAAPIDHKPCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIH 1784

Query: 582  GLVLFQLSAAG-DVFYQQLRPQVDSSLRRDA----GPPGDTQP 619
               + ++  AG   F  +L+P+   S +R       PP   QP
Sbjct: 1785 ASQIQKVEPAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQP 1827



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 27/104 (25%), Positives = 45/104 (43%), Gaps = 2/104 (1%)

Query: 750  PKRRTQLSSSFSLSGHVDPSEDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPS 809
            PK  +Q + S +    V   E    P +PE  P+ +   P T+ P+ ++T    ++    
Sbjct: 1139 PKPTSQATRSRTNRSSVKTPEPVV-PTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVK 1197

Query: 810  EQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTP 853
                ++   + +L P   T    T+ P SQA+  R  RS   TP
Sbjct: 1198 TPETVVPTAL-ELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTP 1240



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 8/99 (8%)

Query: 773  SSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSE--QRQMLRDYMAKLPPQRDTPG 830
            SS  +P+     A  L P TP  Q +TP+A AQG  S+  +   +R       P+  +P 
Sbjct: 1645 SSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPV 1704

Query: 831  CATTP----PHSQASSVRATRSQQHTPVLSSSQPLRKKP 865
                P    P +Q S ++  R+  +   L++  P+  KP
Sbjct: 1705 TTDQPISPEPITQPSCIKRQRAAGNPGSLAA--PIDHKP 1741



 Score = 31.2 bits (69), Expect = 4.4
 Identities = 25/91 (27%), Positives = 36/91 (39%), Gaps = 7/91 (7%)

Query: 770  EDTSSPHSPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQR-------QMLRDYMAKL 822
            ++ SS  +PE     A  L P+T   Q +TP+  +Q              + +     +L
Sbjct: 1396 KNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPEL 1455

Query: 823  PPQRDTPGCATTPPHSQASSVRATRSQQHTP 853
             P   T    T  P SQA+  R  RS   TP
Sbjct: 1456 QPSTSTDQPVTPEPTSQATRGRTDRSSVKTP 1486



 Score = 30.4 bits (67), Expect = 7.4
 Identities = 32/129 (24%), Positives = 50/129 (38%), Gaps = 7/129 (5%)

Query: 740  TSEP-GRQTRRPKRRTQLSSSFSL---SGHVDPSEDTSSPHSPEWPPADALPLPPTTPPS 795
            TSEP  R TR  K R+ + +  ++   +  + PS  T  P +PE P + A      T  S
Sbjct: 1507 TSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPE-PTSRATR--GRTNRS 1563

Query: 796  QELTPDACAQGVPSEQRQMLRDYMAKLPPQRDTPGCATTPPHSQASSVRATRSQQHTPVL 855
               TP++     P  Q    R+ +    P      C T     +        + +  P  
Sbjct: 1564 SVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTT 1623

Query: 856  SSSQPLRKK 864
            S+ QP+  K
Sbjct: 1624 STDQPVTPK 1632


>gi|113427525 PREDICTED: similar to hCG2037003 [Homo sapiens]
          Length = 196

 Score = 36.6 bits (83), Expect = 0.10
 Identities = 55/209 (26%), Positives = 75/209 (35%), Gaps = 40/209 (19%)

Query: 612 GPPG-DTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPVWTAPTFTHRQMLGSTELR 670
           GPPG +T P   APTA              +  L++P   P W A      +  G   LR
Sbjct: 17  GPPGPETPPPAPAPTA--------------RPRLRLPA--PDWRARRADLTRRKG---LR 57

Query: 671 REEEEGQRLGVLRKAMARGQLLLQRDLGSLPAAEPPP----APESGLEDKLSERLGEAWA 726
           R E   + LG    A  R Q+   + + + P+ E  P    A   G          +   
Sbjct: 58  RGEPGSRGLGEGPAAARRPQV---QSIDTTPSGEGAPSFSRAQRPGRSGPSPSLASDPAP 114

Query: 727 GRGAAW-----WERQQGRTSEPGRQTRRPKRRTQLSSSFSLSGHVDPSEDTSSPHSPEW- 780
           GRGAAW      +RQQ   SE G +  R  R  ++           P   +  P   +W 
Sbjct: 115 GRGAAWGSLRPGKRQQALESEAGGRASREARAAEVRERI-------PGGGSWCPGRRDWL 167

Query: 781 PPADALPLPPTTPPSQELTPDACAQGVPS 809
            P  A      T PS    P   A  +P+
Sbjct: 168 TPPCAGSSSQLTEPSVIQQPSISAPNMPN 196


>gi|89941470 ankyrin repeat domain 34 [Homo sapiens]
          Length = 496

 Score = 36.6 bits (83), Expect = 0.10
 Identities = 92/357 (25%), Positives = 117/357 (32%), Gaps = 85/357 (23%)

Query: 496 PPRPSCVQPLLLGGQGG--------QLQLLHLAGEGASVPR--------------LAGPP 533
           PP P    P       G        QLQ     G G   PR              L  PP
Sbjct: 163 PPSPGVEDPAPASPSPGFCTSPSEIQLQTAGGGGRGMLSPRAQEEEEKRDVFEFPLPKPP 222

Query: 534 QSLPSRIDSLPAFPLLEPKIQWRLQERLKAPTIGLAAVVPPLPSAPTPGLV-LFQLSAAG 592
              PS  + LP  P   PK      +RL +   GL A  PP P  PT G   + +L+A  
Sbjct: 223 DD-PSPSEPLPKPPRHPPKPL----KRLNSEPWGLVA--PPQPVPPTEGRPGIERLTAEF 275

Query: 593 DVFYQQLRPQVDSSLRRDAGPPGDTQPDCHAPTASWTSQDTAGCSQWLKALLKVPLAPPV 652
           +      RP++  S R     P D  P        W  + T+G       L +   AP  
Sbjct: 276 NGLTLTGRPRL--SRRHSTEGPEDPPP--------WAEKVTSG-----GPLSRRNTAPEA 320

Query: 653 W-TAPTFTHRQMLGSTE---------LRREEEEGQRLGVLRKAMARGQLLLQRDLGSLPA 702
             + P    RQ L   E         L  +  E  RL + R+  +   L       +LP 
Sbjct: 321 QESGPPSGLRQKLSRMEPVELDTPGHLCPDSPESSRLSLERRRYSASPL-------TLPP 373

Query: 703 AEPPPAPESGLEDKLSERLGEAWAGRGAAWWERQQGRTSEPGRQTRRPKRRTQLSSSFSL 762
           A   P+P    E              GA       GR   PG   RR        S   L
Sbjct: 374 AGSAPSPRQSQESL-----------PGAV--SPLSGRRRSPGLLERR-------GSGTLL 413

Query: 763 SGHVDPSEDTSSPH---SPEWPPADALPLPPTTPPSQELTPDACAQGVPSEQRQMLR 816
             H+  +     P    SP  P  D  P P    PS    P A A G P  +R+++R
Sbjct: 414 LDHISQTRPGFLPPLNVSPHPPIPDIRPQPGGRAPSLPAPPYAGAPGSPRTKRKLVR 470


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,885,400
Number of Sequences: 37866
Number of extensions: 2532665
Number of successful extensions: 11846
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 276
Number of HSP's that attempted gapping in prelim test: 10953
Number of HSP's gapped (non-prelim): 1103
length of query: 869
length of database: 18,247,518
effective HSP length: 111
effective length of query: 758
effective length of database: 14,044,392
effective search space: 10645649136
effective search space used: 10645649136
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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