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Search of human proteins with 215272332
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|215272332 sodium channel, voltage-gated, type IV, beta
isoform 2 [Homo sapiens]
(94 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|215272332 sodium channel, voltage-gated, type IV, beta isofor... 185 8e-48
gi|28372555 sodium channel, voltage-gated, type IV, beta isoform... 141 1e-34
gi|215272334 sodium channel, voltage-gated, type IV, beta isofor... 141 1e-34
gi|4759066 sodium channel, voltage-gated, type II, beta [Homo sa... 32 0.084
gi|30410805 CUB domain-containing protein 1 isoform 1 [Homo sapi... 29 0.93
gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens] 28 1.2
gi|241896926 protein tyrosine phosphatase, receptor type, H isof... 28 1.2
gi|241896924 protein tyrosine phosphatase, receptor type, H isof... 28 1.2
gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens] 28 1.2
gi|4505243 myelin protein zero [Homo sapiens] 28 1.2
gi|13376856 solute carrier family 19, member 3 [Homo sapiens] 28 1.2
gi|188595677 integrin, beta 2 precursor [Homo sapiens] 28 1.6
gi|89191865 integrin, beta 2 precursor [Homo sapiens] 28 1.6
gi|40548378 syndecan 2 precursor [Homo sapiens] 28 1.6
gi|187960059 syndecan 3 [Homo sapiens] 28 1.6
gi|187829485 autism susceptibility candidate 2 isoform 3 [Homo s... 28 1.6
gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo s... 28 1.6
gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sa... 28 1.6
gi|156627577 transglutaminase 4 (prostate) [Homo sapiens] 28 1.6
gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] 28 1.6
gi|4503173 coxsackie virus and adenovirus receptor precursor [Ho... 28 2.1
gi|47519929 cell recognition molecule CASPR3 [Homo sapiens] 27 2.7
gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens] 27 2.7
gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens] 27 2.7
gi|239756081 PREDICTED: hypothetical protein [Homo sapiens] 27 3.5
gi|239750610 PREDICTED: hypothetical protein [Homo sapiens] 27 3.5
gi|239744917 PREDICTED: hypothetical protein XP_002343306 [Homo ... 27 3.5
gi|157419150 protein tyrosine phosphatase, receptor type, M isof... 27 3.5
gi|157419152 protein tyrosine phosphatase, receptor type, M isof... 27 3.5
gi|210147567 hypothetical protein LOC220081 [Homo sapiens] 27 3.5
>gi|215272332 sodium channel, voltage-gated, type IV, beta isoform
2 [Homo sapiens]
Length = 94
Score = 185 bits (469), Expect = 8e-48
Identities = 94/94 (100%), Positives = 94/94 (100%)
Query: 1 MPGAGDGGKAPARWLGTGLLVEEVDNTVTLIILAVVGGVIGLLILILLIKKLIIFILKKT 60
MPGAGDGGKAPARWLGTGLLVEEVDNTVTLIILAVVGGVIGLLILILLIKKLIIFILKKT
Sbjct: 1 MPGAGDGGKAPARWLGTGLLVEEVDNTVTLIILAVVGGVIGLLILILLIKKLIIFILKKT 60
Query: 61 REKKKECLVSSSGNDNTENGLPGSKAEEKPPSKV 94
REKKKECLVSSSGNDNTENGLPGSKAEEKPPSKV
Sbjct: 61 REKKKECLVSSSGNDNTENGLPGSKAEEKPPSKV 94
>gi|28372555 sodium channel, voltage-gated, type IV, beta isoform 1
precursor [Homo sapiens]
Length = 228
Score = 141 bits (355), Expect = 1e-34
Identities = 73/74 (98%), Positives = 74/74 (100%)
Query: 21 VEEVDNTVTLIILAVVGGVIGLLILILLIKKLIIFILKKTREKKKECLVSSSGNDNTENG 80
+EEVDNTVTLIILAVVGGVIGLLILILLIKKLIIFILKKTREKKKECLVSSSGNDNTENG
Sbjct: 155 LEEVDNTVTLIILAVVGGVIGLLILILLIKKLIIFILKKTREKKKECLVSSSGNDNTENG 214
Query: 81 LPGSKAEEKPPSKV 94
LPGSKAEEKPPSKV
Sbjct: 215 LPGSKAEEKPPSKV 228
Score = 47.4 bits (111), Expect = 3e-06
Identities = 20/20 (100%), Positives = 20/20 (100%)
Query: 1 MPGAGDGGKAPARWLGTGLL 20
MPGAGDGGKAPARWLGTGLL
Sbjct: 1 MPGAGDGGKAPARWLGTGLL 20
>gi|215272334 sodium channel, voltage-gated, type IV, beta isoform 3
[Homo sapiens]
Length = 118
Score = 141 bits (355), Expect = 1e-34
Identities = 73/74 (98%), Positives = 74/74 (100%)
Query: 21 VEEVDNTVTLIILAVVGGVIGLLILILLIKKLIIFILKKTREKKKECLVSSSGNDNTENG 80
+EEVDNTVTLIILAVVGGVIGLLILILLIKKLIIFILKKTREKKKECLVSSSGNDNTENG
Sbjct: 45 LEEVDNTVTLIILAVVGGVIGLLILILLIKKLIIFILKKTREKKKECLVSSSGNDNTENG 104
Query: 81 LPGSKAEEKPPSKV 94
LPGSKAEEKPPSKV
Sbjct: 105 LPGSKAEEKPPSKV 118
>gi|4759066 sodium channel, voltage-gated, type II, beta [Homo
sapiens]
Length = 215
Score = 32.3 bits (72), Expect = 0.084
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 8/58 (13%)
Query: 23 EVDNTVTLIILAVVGGVIGLLILILLIKKLIIFILKKTREKKKECLVSSSGNDNTENG 80
E D+TV +I+ A VGG + ++IL+L++ K + +KKE +S+ E G
Sbjct: 153 ERDSTVAVIVGASVGGFLAVVILVLMVVKCV--------RRKKEQKLSTDDLKTEEEG 202
>gi|30410805 CUB domain-containing protein 1 isoform 1 [Homo
sapiens]
Length = 836
Score = 28.9 bits (63), Expect = 0.93
Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 4/55 (7%)
Query: 28 VTLIILAVVGGVIGLLILILLIKKLIIFILKKTREKKKECLVSSSGNDNTENGLP 82
+T+I++A VGG G+L+L L LII +KK ++K + NDN +P
Sbjct: 666 LTVILIAAVGG--GVLLLSAL--GLIICCVKKKKKKTNKGPAVGIYNDNINTEMP 716
>gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens]
Length = 882
Score = 28.5 bits (62), Expect = 1.2
Identities = 14/33 (42%), Positives = 24/33 (72%), Gaps = 3/33 (9%)
Query: 32 ILAVVGGVIGLLILILLIKKLIIFILKKTREKK 64
IL ++GG++ LLILILL L++F+ ++ K+
Sbjct: 710 ILGILGGILALLILILL---LLLFLRRRAVVKE 739
>gi|241896926 protein tyrosine phosphatase, receptor type, H isoform
2 precursor [Homo sapiens]
Length = 937
Score = 28.5 bits (62), Expect = 1.2
Identities = 11/32 (34%), Positives = 23/32 (71%), Gaps = 1/32 (3%)
Query: 35 VVGGVIGLLILILLIKKLIIFILKKTREKKKE 66
+ G +G+L+ ++L+ L+IF LK+ +KK++
Sbjct: 577 IAGAFVGILLFLILVG-LLIFFLKRRNKKKQQ 607
>gi|241896924 protein tyrosine phosphatase, receptor type, H isoform
1 precursor [Homo sapiens]
Length = 1115
Score = 28.5 bits (62), Expect = 1.2
Identities = 11/32 (34%), Positives = 23/32 (71%), Gaps = 1/32 (3%)
Query: 35 VVGGVIGLLILILLIKKLIIFILKKTREKKKE 66
+ G +G+L+ ++L+ L+IF LK+ +KK++
Sbjct: 755 IAGAFVGILLFLILVG-LLIFFLKRRNKKKQQ 785
>gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]
Length = 517
Score = 28.5 bits (62), Expect = 1.2
Identities = 15/52 (28%), Positives = 29/52 (55%), Gaps = 3/52 (5%)
Query: 34 AVVGGVIGLLILILLIKKLIIFILKKTREKKKECLVSSS---GNDNTENGLP 82
A++GGV G ++L+L++ I+ L++ R K + GN ++ G+P
Sbjct: 355 AIIGGVAGSILLVLIVVGGIVVALRRRRHTFKGDYSTKKHVYGNGYSKAGIP 406
>gi|4505243 myelin protein zero [Homo sapiens]
Length = 258
Score = 28.5 bits (62), Expect = 1.2
Identities = 11/28 (39%), Positives = 22/28 (78%)
Query: 22 EEVDNTVTLIILAVVGGVIGLLILILLI 49
E+V +++ AV+GGV+G+++L+LL+
Sbjct: 158 EKVPTRYGVVLGAVIGGVLGVVLLLLLL 185
>gi|13376856 solute carrier family 19, member 3 [Homo sapiens]
Length = 496
Score = 28.5 bits (62), Expect = 1.2
Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
Query: 28 VTLIILAVVGGVIGLLILILLIKKLIIFILKKTREKKKECLVSSSGNDNTENGLPGSKAE 87
+ +I LA V + + + KK + F K +RE KK V+ + E PG + E
Sbjct: 172 LNVISLASVSVAFLFSLFLPMPKKSMFFHAKPSREIKKSSSVNPVLEETHEGEAPGCE-E 230
Query: 88 EKPPSKV 94
+KP S++
Sbjct: 231 QKPTSEI 237
>gi|188595677 integrin, beta 2 precursor [Homo sapiens]
Length = 769
Score = 28.1 bits (61), Expect = 1.6
Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 6/51 (11%)
Query: 32 ILAVVGG------VIGLLILILLIKKLIIFILKKTREKKKECLVSSSGNDN 76
I A+VGG +IG+L+L++ + + L++ R +KE L S NDN
Sbjct: 701 IAAIVGGTVAGIVLIGILLLVIWKALIHLSDLREYRRFEKEKLKSQWNNDN 751
>gi|89191865 integrin, beta 2 precursor [Homo sapiens]
Length = 769
Score = 28.1 bits (61), Expect = 1.6
Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 6/51 (11%)
Query: 32 ILAVVGG------VIGLLILILLIKKLIIFILKKTREKKKECLVSSSGNDN 76
I A+VGG +IG+L+L++ + + L++ R +KE L S NDN
Sbjct: 701 IAAIVGGTVAGIVLIGILLLVIWKALIHLSDLREYRRFEKEKLKSQWNNDN 751
>gi|40548378 syndecan 2 precursor [Homo sapiens]
Length = 201
Score = 28.1 bits (61), Expect = 1.6
Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 12/66 (18%)
Query: 29 TLIILAVV-GGVIGLLILILLIKKLIIFILKKTREKKKECLVSSSGNDNTENGLPGSKAE 87
T ++ AV+ GGVIG L I LI L+ + KK G+ + P S A
Sbjct: 143 TEVLAAVIAGGVIGFLFAIFLILLLVYRMRKK-----------DEGSYDLGERKPSSAAY 191
Query: 88 EKPPSK 93
+K P+K
Sbjct: 192 QKAPTK 197
>gi|187960059 syndecan 3 [Homo sapiens]
Length = 442
Score = 28.1 bits (61), Expect = 1.6
Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 5/54 (9%)
Query: 30 LIILAVVGGVIGLLILILLIKKLIIFILKK-----TREKKKECLVSSSGNDNTE 78
+++ +VGGV+G L L+ LI + KK T E+ K+ V+ D E
Sbjct: 385 VLVAVIVGGVVGALFAAFLVTLLIYRMKKKDEGSYTLEEPKQASVTYQKPDKQE 438
>gi|187829485 autism susceptibility candidate 2 isoform 3 [Homo
sapiens]
Length = 266
Score = 28.1 bits (61), Expect = 1.6
Identities = 12/23 (52%), Positives = 15/23 (65%)
Query: 68 LVSSSGNDNTENGLPGSKAEEKP 90
L SSSG+D +NG P S A +P
Sbjct: 48 LASSSGSDKEDNGKPPSSAPSRP 70
>gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo
sapiens]
Length = 1235
Score = 28.1 bits (61), Expect = 1.6
Identities = 12/23 (52%), Positives = 15/23 (65%)
Query: 68 LVSSSGNDNTENGLPGSKAEEKP 90
L SSSG+D +NG P S A +P
Sbjct: 48 LASSSGSDKEDNGKPPSSAPSRP 70
>gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo
sapiens]
Length = 1259
Score = 28.1 bits (61), Expect = 1.6
Identities = 12/23 (52%), Positives = 15/23 (65%)
Query: 68 LVSSSGNDNTENGLPGSKAEEKP 90
L SSSG+D +NG P S A +P
Sbjct: 48 LASSSGSDKEDNGKPPSSAPSRP 70
>gi|156627577 transglutaminase 4 (prostate) [Homo sapiens]
Length = 684
Score = 28.1 bits (61), Expect = 1.6
Identities = 17/79 (21%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 3 GAGDGGKAPARWLGTGLLVEEVDNTVTLIILA---VVGGVIGLLILILLIKKLIIFILKK 59
G +GG AP +W G+ ++++ NT + V G++ ++ L I +
Sbjct: 235 GDYEGGTAPYKWTGSAPILQQYYNTKQAVCFGQCWVFAGILTTVLRALGIPARSVTGFDS 294
Query: 60 TREKKKECLVSSSGNDNTE 78
+ ++ V + N+N E
Sbjct: 295 AHDTERNLTVDTYVNENGE 313
>gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]
Length = 794
Score = 28.1 bits (61), Expect = 1.6
Identities = 10/35 (28%), Positives = 24/35 (68%)
Query: 37 GGVIGLLILILLIKKLIIFILKKTREKKKECLVSS 71
G +I +L+ I+++ +++ + R+KKK+ L++S
Sbjct: 615 GALIAILLCIVILLAIVVLYVALRRQKKKDTLMTS 649
>gi|4503173 coxsackie virus and adenovirus receptor precursor [Homo
sapiens]
Length = 365
Score = 27.7 bits (60), Expect = 2.1
Identities = 13/32 (40%), Positives = 19/32 (59%)
Query: 35 VVGGVIGLLILILLIKKLIIFILKKTREKKKE 66
+ G +IG L+ + LI +I KK RE+K E
Sbjct: 239 IAGAIIGTLLALALIGLIIFCCRKKRREEKYE 270
>gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]
Length = 1288
Score = 27.3 bits (59), Expect = 2.7
Identities = 14/33 (42%), Positives = 21/33 (63%)
Query: 34 AVVGGVIGLLILILLIKKLIIFILKKTREKKKE 66
AV+GGVI ++I ILL I + + R+ +KE
Sbjct: 1245 AVIGGVIAVVIFILLCITAIAIRIYQQRKLRKE 1277
>gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 27.3 bits (59), Expect = 2.7
Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 8/48 (16%)
Query: 32 ILAVVGGVIGLLILILLIKKLIIFILKKTREKKKECLVSSSGNDNTEN 79
++A++ V+ LL+LILLI + R +KKE L+ D EN
Sbjct: 610 LIAILACVLTLLVLILLIVTM--------RRRKKEPLIFDEERDIREN 649
>gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 27.3 bits (59), Expect = 2.7
Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 8/48 (16%)
Query: 32 ILAVVGGVIGLLILILLIKKLIIFILKKTREKKKECLVSSSGNDNTEN 79
++A++ V+ LL+LILLI + R +KKE L+ D EN
Sbjct: 610 LIAILACVLTLLVLILLIVTM--------RRRKKEPLIFDEERDIREN 649
>gi|239756081 PREDICTED: hypothetical protein [Homo sapiens]
Length = 244
Score = 26.9 bits (58), Expect = 3.5
Identities = 16/36 (44%), Positives = 20/36 (55%)
Query: 5 GDGGKAPARWLGTGLLVEEVDNTVTLIILAVVGGVI 40
G G A A+W GT E + N + ILA +GGVI
Sbjct: 191 GIGHLAEAQWCGTLPHAERLANGLVCGILAHLGGVI 226
>gi|239750610 PREDICTED: hypothetical protein [Homo sapiens]
Length = 248
Score = 26.9 bits (58), Expect = 3.5
Identities = 16/36 (44%), Positives = 20/36 (55%)
Query: 5 GDGGKAPARWLGTGLLVEEVDNTVTLIILAVVGGVI 40
G G A A+W GT E + N + ILA +GGVI
Sbjct: 195 GIGHLAEAQWCGTLPHAERLANGLVCGILAHLGGVI 230
>gi|239744917 PREDICTED: hypothetical protein XP_002343306 [Homo
sapiens]
Length = 248
Score = 26.9 bits (58), Expect = 3.5
Identities = 16/36 (44%), Positives = 20/36 (55%)
Query: 5 GDGGKAPARWLGTGLLVEEVDNTVTLIILAVVGGVI 40
G G A A+W GT E + N + ILA +GGVI
Sbjct: 195 GIGHLAEAQWCGTLPHAERLANGLVCGILAHLGGVI 230
>gi|157419150 protein tyrosine phosphatase, receptor type, M isoform
2 precursor [Homo sapiens]
Length = 1452
Score = 26.9 bits (58), Expect = 3.5
Identities = 16/69 (23%), Positives = 38/69 (55%), Gaps = 7/69 (10%)
Query: 22 EEVDNTVTLIILAVVGGVIGLLILILLIKKLIIFILKKTREKKKECLVSSSGNDNT--EN 79
++ D+TV + G + G+L+ +++ +++ + K+ KK++ +SS+ + T N
Sbjct: 735 KQTDHTVK-----IAGVIAGILLFVIIFLGVVLVMKKRKLAKKRKETMSSTRQEMTVMVN 789
Query: 80 GLPGSKAEE 88
+ S AE+
Sbjct: 790 SMDKSYAEQ 798
>gi|157419152 protein tyrosine phosphatase, receptor type, M isoform
1 precursor [Homo sapiens]
Length = 1465
Score = 26.9 bits (58), Expect = 3.5
Identities = 16/69 (23%), Positives = 38/69 (55%), Gaps = 7/69 (10%)
Query: 22 EEVDNTVTLIILAVVGGVIGLLILILLIKKLIIFILKKTREKKKECLVSSSGNDNT--EN 79
++ D+TV + G + G+L+ +++ +++ + K+ KK++ +SS+ + T N
Sbjct: 735 KQTDHTVK-----IAGVIAGILLFVIIFLGVVLVMKKRKLAKKRKETMSSTRQEMTVMVN 789
Query: 80 GLPGSKAEE 88
+ S AE+
Sbjct: 790 SMDKSYAEQ 798
>gi|210147567 hypothetical protein LOC220081 [Homo sapiens]
Length = 696
Score = 26.9 bits (58), Expect = 3.5
Identities = 13/37 (35%), Positives = 22/37 (59%)
Query: 38 GVIGLLILILLIKKLIIFILKKTREKKKECLVSSSGN 74
G + +LIL +KK IL+ + E + L+++SGN
Sbjct: 502 GNLAMLILYAKMKKFTYIILEDSLEGRIRALINNSGN 538
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.139 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,173,449
Number of Sequences: 37866
Number of extensions: 154613
Number of successful extensions: 608
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 567
Number of HSP's gapped (non-prelim): 66
length of query: 94
length of database: 18,247,518
effective HSP length: 65
effective length of query: 29
effective length of database: 15,786,228
effective search space: 457800612
effective search space used: 457800612
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.