Search of human proteins with 214829714

Search of human proteins with 214829714

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|214829714 ADP-ribosylation factor GTPase activating protein
3 isoform 2 [Homo sapiens]
         (472 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|214829714 ADP-ribosylation factor GTPase activating protein 3...   942   0.0  
gi|214829673 ADP-ribosylation factor GTPase activating protein 3...   921   0.0  
gi|31543983 ADP-ribosylation factor GTPase activating protein 2 ...   439   e-123
gi|8922652 ADP-ribosylation factor GTPase activating protein 1 i...    94   2e-19
gi|28416436 ADP-ribosylation factor GTPase activating protein 1 ...    94   3e-19
gi|113204622 stromal membrane-associated GTPase-activating prote...    81   2e-15
gi|21264558 stromal membrane-associated GTPase-activating protei...    81   2e-15
gi|23943872 small ArfGAP2 [Homo sapiens]                               79   9e-15
gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma...    77   3e-14
gi|187608516 centaurin, beta 2 [Homo sapiens]                          77   3e-14
gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens]               74   2e-13
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]          74   3e-13
gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens]            74   3e-13
gi|46094081 development and differentiation enhancing factor 1 [...    74   3e-13
gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]                73   6e-13
gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]                73   6e-13
gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activat...    69   7e-12
gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH do...    69   9e-12
gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens]     69   9e-12
gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH do...    69   9e-12
gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repea...    67   3e-11
gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repea...    67   3e-11
gi|7661880 centaurin beta1 [Homo sapiens]                              67   3e-11
gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH do...    67   4e-11
gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH do...    65   2e-10
gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domai...    64   3e-10
gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain ...    64   3e-10
gi|6806913 centaurin, alpha 1 [Homo sapiens]                           64   3e-10
gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domai...    62   1e-09
gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain...    62   1e-09

>gi|214829714 ADP-ribosylation factor GTPase activating protein 3
           isoform 2 [Homo sapiens]
          Length = 472

 Score =  942 bits (2436), Expect = 0.0
 Identities = 472/472 (100%), Positives = 472/472 (100%)

Query: 1   MGDPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLS 60
           MGDPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLS
Sbjct: 1   MGDPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLS 60

Query: 61  FIRSTELDSNWSWFQLRCMQVGGNASALWLDSCVVPPLSPPPKEEDFFASHVSPEVSDTA 120
           FIRSTELDSNWSWFQLRCMQVGGNASALWLDSCVVPPLSPPPKEEDFFASHVSPEVSDTA
Sbjct: 61  FIRSTELDSNWSWFQLRCMQVGGNASALWLDSCVVPPLSPPPKEEDFFASHVSPEVSDTA 120

Query: 121 WASAIAEPSSLTSRPVETTLENNEGGQEQGPSVEGLNVPTKATLEVSSIIKKKPNQAKKG 180
           WASAIAEPSSLTSRPVETTLENNEGGQEQGPSVEGLNVPTKATLEVSSIIKKKPNQAKKG
Sbjct: 121 WASAIAEPSSLTSRPVETTLENNEGGQEQGPSVEGLNVPTKATLEVSSIIKKKPNQAKKG 180

Query: 181 LGAKKGSLGAQKLANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEI 240
           LGAKKGSLGAQKLANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEI
Sbjct: 181 LGAKKGSLGAQKLANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEI 240

Query: 241 QMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDD 300
           QMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDD
Sbjct: 241 QMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDD 300

Query: 301 SDDSYFTSSSSYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARR 360
           SDDSYFTSSSSYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARR
Sbjct: 301 SDDSYFTSSSSYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARR 360

Query: 361 KPDYEPVENTDEAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEE 420
           KPDYEPVENTDEAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEE
Sbjct: 361 KPDYEPVENTDEAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEE 420

Query: 421 PRKQPAGNYSLSSVLPNAPDMAQFKQGVRSVAGKLSVFANGVVTSIQDRYGS 472
           PRKQPAGNYSLSSVLPNAPDMAQFKQGVRSVAGKLSVFANGVVTSIQDRYGS
Sbjct: 421 PRKQPAGNYSLSSVLPNAPDMAQFKQGVRSVAGKLSVFANGVVTSIQDRYGS 472


>gi|214829673 ADP-ribosylation factor GTPase activating protein 3
           isoform 1 [Homo sapiens]
          Length = 516

 Score =  921 bits (2381), Expect = 0.0
 Identities = 472/516 (91%), Positives = 472/516 (91%), Gaps = 44/516 (8%)

Query: 1   MGDPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLS 60
           MGDPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLS
Sbjct: 1   MGDPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLS 60

Query: 61  FIRSTELDSNWSWFQLRCMQVGGNASA--------------------------------- 87
           FIRSTELDSNWSWFQLRCMQVGGNASA                                 
Sbjct: 61  FIRSTELDSNWSWFQLRCMQVGGNASASSFFHQHGCSTNDTNAKYNSRAAQLYREKIKSL 120

Query: 88  -----------LWLDSCVVPPLSPPPKEEDFFASHVSPEVSDTAWASAIAEPSSLTSRPV 136
                      LWLDSCVVPPLSPPPKEEDFFASHVSPEVSDTAWASAIAEPSSLTSRPV
Sbjct: 121 ASQATRKHGTDLWLDSCVVPPLSPPPKEEDFFASHVSPEVSDTAWASAIAEPSSLTSRPV 180

Query: 137 ETTLENNEGGQEQGPSVEGLNVPTKATLEVSSIIKKKPNQAKKGLGAKKGSLGAQKLANT 196
           ETTLENNEGGQEQGPSVEGLNVPTKATLEVSSIIKKKPNQAKKGLGAKKGSLGAQKLANT
Sbjct: 181 ETTLENNEGGQEQGPSVEGLNVPTKATLEVSSIIKKKPNQAKKGLGAKKGSLGAQKLANT 240

Query: 197 CFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNV 256
           CFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNV
Sbjct: 241 CFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNV 300

Query: 257 DSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEP 316
           DSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEP
Sbjct: 301 DSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEP 360

Query: 317 VELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTDEAQKK 376
           VELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTDEAQKK
Sbjct: 361 VELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTDEAQKK 420

Query: 377 FGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLP 436
           FGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLP
Sbjct: 421 FGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLP 480

Query: 437 NAPDMAQFKQGVRSVAGKLSVFANGVVTSIQDRYGS 472
           NAPDMAQFKQGVRSVAGKLSVFANGVVTSIQDRYGS
Sbjct: 481 NAPDMAQFKQGVRSVAGKLSVFANGVVTSIQDRYGS 516


>gi|31543983 ADP-ribosylation factor GTPase activating protein 2
           [Homo sapiens]
          Length = 521

 Score =  439 bits (1129), Expect = e-123
 Identities = 260/529 (49%), Positives = 334/529 (63%), Gaps = 71/529 (13%)

Query: 3   DPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFI 62
           +P+K +I T+FKRLR+VPTNK CFDCGAKNPSWASITYGVFLCIDCSG HRSLGVHLSFI
Sbjct: 4   EPNKTEIQTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFI 63

Query: 63  RSTELDSNWSWFQLRCMQVGGNASA----------------------------------- 87
           RSTELDSNW+WFQLRCMQVGGNA+A                                   
Sbjct: 64  RSTELDSNWNWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQMYREKIRQLGS 123

Query: 88  ---------LWLD--SCVVPPLSPPPKEEDFFASHVSPEVSDTAWASAIAEPSSLTSRPV 136
                    LW+D  S  VP  SP  K+ DFF  H  P     AW +   EPS  T +P 
Sbjct: 124 AALARHGTDLWIDNMSSAVPNHSPEKKDSDFFTEHTQPP----AWDAPATEPSG-TQQPA 178

Query: 137 ETTLENNEGGQEQGPSVEGLNVPTKATLEVSSII--KKKPNQAKKGLGAKKGSLGAQKLA 194
            +T  +     E GP+ + L    KA+LE+ S I  KKKP  AKKGLGAKKG LGAQK++
Sbjct: 179 PSTESSGLAQPEHGPNTDLLGTSPKASLELKSSIIGKKKPAAAKKGLGAKKG-LGAQKVS 237

Query: 195 NTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEK--MNISG 252
           +  F+EIE+QAQ A+K++EQ+        EES+V+S+RLAY++L+I  KK+EK   N+ G
Sbjct: 238 SQSFSEIERQAQVAEKLREQQAADAKKQAEESMVASMRLAYQELQIDRKKEEKKLQNLEG 297

Query: 253 KKNVDSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDDSDD--SYFTSSS 310
           KK   ++RLGMG  + RS +SHSV S+MQ IEQE+P+ AK  +   D  DD  ++ +   
Sbjct: 298 KKREQAERLGMGLVS-RSSVSHSVLSEMQVIEQETPVSAKSSRSQLDLFDDVGTFASGPP 356

Query: 311 SYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVEN- 369
            Y D P  L  S  S WD  +D+ W  +  ++ E   + T  S RP + R  +   VE+ 
Sbjct: 357 KYKDNPFSLGESFGSRWD--TDAAWGMDRVEEKEP--EVTISSIRPISERATNRREVESR 412

Query: 370 -----TDEAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLF-EEPRK 423
                + EA++KF   KAISSDM+FGR+  A+YE R+RL++LS SS+ISS+DLF +    
Sbjct: 413 SSGLESSEARQKFAGAKAISSDMFFGREVDAEYEARSRLQQLSGSSAISSSDLFGDMDGA 472

Query: 424 QPAGNYSLSSVLPNAPDMAQFKQGVRSVAGKLSVFANGVVTSIQDRYGS 472
             AG+ SL +VLP A D+AQFKQGV+SVAGK++V ANGV+ S+QDRYGS
Sbjct: 473 HGAGSVSLGNVLPTA-DIAQFKQGVKSVAGKMAVLANGVMNSLQDRYGS 520


>gi|8922652 ADP-ribosylation factor GTPase activating protein 1
           isoform a [Homo sapiens]
          Length = 406

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 105/376 (27%), Positives = 156/376 (41%), Gaps = 69/376 (18%)

Query: 12  IFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNW 71
           + K +R    N VCF+CGA NP W S+TYG+++C++CSG HR LGVHLSF+RS  +D  W
Sbjct: 9   VLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDK-W 67

Query: 72  SWFQLRCMQVGGN--------------------------ASALWLDSCVVPPLSPPPKEE 105
              +L  M+ GGN                          A+AL+ D  V          E
Sbjct: 68  KDIELEKMKAGGNAKFREFLESQEDYDPCWSLQEKYNSRAAALFRDKVVALAEGREWSLE 127

Query: 106 DFFASHVSPEVSDTAWASA---IAEPSSLTS---RPVETTLENNEGGQE--QGPSVEGL- 156
              A + +P    T  +       +P S+T+   +  E  L ++ G  +  QG    G  
Sbjct: 128 SSPAQNWTPPQPRTLPSMVHRVSGQPQSVTASSDKAFEDWLNDDLGSYQGAQGNRYVGFG 187

Query: 157 NVPTKATLE-------VSSIIK----------KKPNQAKKGLGAKKGSLGAQK---LANT 196
           N P     E       +SS+            +  + AK+G   K GS  +QK   L ++
Sbjct: 188 NTPPPQKKEDDFLNNAMSSLYSGWSSFTTGASRFASAAKEG-ATKFGSQASQKASELGHS 246

Query: 197 CFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNV 256
               + K AQ  +K+KE     K+     S VS L    + +  +  +D     SGK   
Sbjct: 247 LNENVLKPAQ--EKVKE----GKIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEG 300

Query: 257 DSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEP 316
             D    G     S + H   S++     E+   A+P K     S DS+  + +S     
Sbjct: 301 PLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKTRKSPSSDSWTCADTS----- 355

Query: 317 VELRSS-SFSSWDDSS 331
            E RSS S+  W  +S
Sbjct: 356 TERRSSDSWEVWGSAS 371


>gi|28416436 ADP-ribosylation factor GTPase activating protein 1
          isoform b [Homo sapiens]
          Length = 414

 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 39/74 (52%), Positives = 52/74 (70%), Gaps = 1/74 (1%)

Query: 12 IFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNW 71
          + K +R    N VCF+CGA NP W S+TYG+++C++CSG HR LGVHLSF+RS  +D  W
Sbjct: 9  VLKEVRVQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMD-KW 67

Query: 72 SWFQLRCMQVGGNA 85
             +L  M+ GGNA
Sbjct: 68 KDIELEKMKAGGNA 81



 Score = 29.3 bits (64), Expect = 8.1
 Identities = 42/156 (26%), Positives = 66/156 (42%), Gaps = 14/156 (8%)

Query: 177 AKKGLGAKKGSLGAQKLANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYK 236
           ++K  G K+    A +L ++    + K AQ  +K+KE     K+     S VS  +LA K
Sbjct: 237 SQKFWGHKQQPEPASELGHSLNENVLKPAQ--EKVKE----GKIFDDVSSGVS--QLASK 288

Query: 237 DLEIQMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKK 296
            +  +  +D     SGK     D    G     S + H   S++     E+   A+P K 
Sbjct: 289 GVGSKGWRDVTTFFSGKAEGPLDSPSEGHSYQNSGLDHFQNSNIDQSFWETFGSAEPTKT 348

Query: 297 YNDDSDDSYFTSSSSYFDEPVELRSS-SFSSWDDSS 331
               S DS+  + +S      E RSS S+  W  +S
Sbjct: 349 RKSPSSDSWTCADTS-----TERRSSDSWEVWGSAS 379


>gi|113204622 stromal membrane-associated GTPase-activating protein
           1 isoform A [Homo sapiens]
          Length = 467

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 43/92 (46%), Positives = 56/92 (60%), Gaps = 2/92 (2%)

Query: 5   SKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRS 64
           ++Q  L + K LR    NK C DC AK P WAS   GVF+CI C+G HR+LGVH+S ++S
Sbjct: 14  NEQHQLILSKLLRE-EDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKS 72

Query: 65  TELDSNWSWFQLRCMQVGGNASALWLDSCVVP 96
             LD  W+  Q++CMQ  GN  A  L    +P
Sbjct: 73  VNLD-QWTAEQIQCMQDMGNTKARLLYEANLP 103


>gi|21264558 stromal membrane-associated GTPase-activating protein 1
           isoform B [Homo sapiens]
          Length = 440

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 43/92 (46%), Positives = 56/92 (60%), Gaps = 2/92 (2%)

Query: 5   SKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRS 64
           ++Q  L + K LR    NK C DC AK P WAS   GVF+CI C+G HR+LGVH+S ++S
Sbjct: 14  NEQHQLILSKLLRE-EDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKS 72

Query: 65  TELDSNWSWFQLRCMQVGGNASALWLDSCVVP 96
             LD  W+  Q++CMQ  GN  A  L    +P
Sbjct: 73  VNLD-QWTAEQIQCMQDMGNTKARLLYEANLP 103


>gi|23943872 small ArfGAP2 [Homo sapiens]
          Length = 429

 Score = 79.0 bits (193), Expect = 9e-15
 Identities = 37/75 (49%), Positives = 48/75 (64%), Gaps = 1/75 (1%)

Query: 22 NKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQLRCMQV 81
          NK C DC +K P WAS   GVF+CI C+G HR+LGVH+S ++S  LD  W+  Q++CMQ 
Sbjct: 25 NKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLD-QWTQEQIQCMQE 83

Query: 82 GGNASALWLDSCVVP 96
           GN  A  L    +P
Sbjct: 84 MGNGKANRLYEAYLP 98


>gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains
           3 [Homo sapiens]
          Length = 834

 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 39/76 (51%), Positives = 50/76 (65%), Gaps = 1/76 (1%)

Query: 11  TIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSN 70
           ++ +R++SV  N  C DCG  +P WASI  GV LCI+CSG HRSLGVH S +RS  LDS 
Sbjct: 404 SVLQRVQSVAGNSQCGDCGQPDPRWASINLGVLLCIECSGIHRSLGVHCSKVRSLTLDS- 462

Query: 71  WSWFQLRCMQVGGNAS 86
           W    L+ M   GN++
Sbjct: 463 WEPELLKLMCELGNSA 478


>gi|187608516 centaurin, beta 2 [Homo sapiens]
          Length = 778

 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 40/86 (46%), Positives = 54/86 (62%), Gaps = 4/86 (4%)

Query: 2   GDPSKQDIL---TIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVH 58
           G+ SK+ +L   +  +R++ +P N  C DCG  +P WASI  G+ LCI+CSG HRSLGVH
Sbjct: 388 GNESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIECSGIHRSLGVH 447

Query: 59  LSFIRSTELDSNWSWFQLRCMQVGGN 84
            S +RS  LD+ W    L+ M   GN
Sbjct: 448 FSKVRSLTLDT-WEPELLKLMCELGN 472


>gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens]
          Length = 911

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 37/81 (45%), Positives = 47/81 (58%), Gaps = 1/81 (1%)

Query: 7   QDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTE 66
           Q+     + +R+V  N  C DC A NP WAS+  G  +CI+CSG HR LG HLS +RS +
Sbjct: 659 QNAALAVQAVRTVRGNSFCIDCDAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLD 718

Query: 67  LDSNWSWFQLRCMQVGGNASA 87
           LD +W    L  M   GNA A
Sbjct: 719 LD-DWPPELLAVMTAMGNALA 738


>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
          Length = 1192

 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 29/53 (54%), Positives = 39/53 (73%)

Query: 16  LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELD 68
           +R+   N +C DCGA NP+WAS+  G  +CI+CSG HR+LG HLS +RS +LD
Sbjct: 937 IRNAKGNSICVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLD 989


>gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens]
          Length = 836

 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 29/53 (54%), Positives = 39/53 (73%)

Query: 16  LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELD 68
           +R+   N +C DCGA NP+WAS+  G  +CI+CSG HR+LG HLS +RS +LD
Sbjct: 581 IRNAKGNSICVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLD 633


>gi|46094081 development and differentiation enhancing factor 1
           [Homo sapiens]
          Length = 1129

 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 37/106 (34%), Positives = 58/106 (54%), Gaps = 1/106 (0%)

Query: 2   GDPSKQDIL-TIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLS 60
           G+ S +D+   I + ++ +P N +C DCG+  P+W S   G+  CI+CSG HR +GVH+S
Sbjct: 430 GENSLEDLTKAIIEDVQRLPGNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGVHIS 489

Query: 61  FIRSTELDSNWSWFQLRCMQVGGNASALWLDSCVVPPLSPPPKEED 106
            I+S ELD   +   L    VG N+    +++ +  P   P    D
Sbjct: 490 RIQSLELDKLGTSELLLAKNVGNNSFNDIMEANLPSPSPKPTPSSD 535


>gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]
          Length = 804

 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 34/79 (43%), Positives = 52/79 (65%), Gaps = 3/79 (3%)

Query: 16  LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQ 75
           +R++  N  C DC  +NP+WAS+  G  +CI+CSG HR+LG HLS +RS +LD +W    
Sbjct: 562 IRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLD-DWPVEL 620

Query: 76  LRCMQVGGN--ASALWLDS 92
           ++ M   GN  A+++W +S
Sbjct: 621 IKVMSSIGNELANSVWEES 639


>gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]
          Length = 857

 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 34/79 (43%), Positives = 52/79 (65%), Gaps = 3/79 (3%)

Query: 16  LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQ 75
           +R++  N  C DC  +NP+WAS+  G  +CI+CSG HR+LG HLS +RS +LD +W    
Sbjct: 615 IRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLD-DWPVEL 673

Query: 76  LRCMQVGGN--ASALWLDS 92
           ++ M   GN  A+++W +S
Sbjct: 674 IKVMSSIGNELANSVWEES 692


>gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activating
           protein 11 [Homo sapiens]
          Length = 550

 Score = 69.3 bits (168), Expect = 7e-12
 Identities = 34/76 (44%), Positives = 48/76 (63%), Gaps = 3/76 (3%)

Query: 16  LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQ 75
           ++++  N  C DC  +NP WAS+  GV +CI+CSG HRSLG  LS +RS ELD +W    
Sbjct: 334 IQNMRGNSHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELD-DWPVEL 392

Query: 76  LRCMQVGGN--ASALW 89
            + M   GN  A+++W
Sbjct: 393 RKVMSSIGNDLANSIW 408


>gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH
           domain 4 [Homo sapiens]
          Length = 663

 Score = 68.9 bits (167), Expect = 9e-12
 Identities = 34/76 (44%), Positives = 48/76 (63%), Gaps = 3/76 (3%)

Query: 16  LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQ 75
           ++++  N  C DC  +NP WAS+  GV +CI+CSG HRSLG  LS +RS ELD +W    
Sbjct: 447 IQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELD-DWPVEL 505

Query: 76  LRCMQVGGN--ASALW 89
            + M   GN  A+++W
Sbjct: 506 RKVMSSIGNDLANSIW 521


>gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens]
          Length = 686

 Score = 68.9 bits (167), Expect = 9e-12
 Identities = 34/76 (44%), Positives = 48/76 (63%), Gaps = 3/76 (3%)

Query: 16  LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQ 75
           ++++  N  C DC  +NP WAS+  GV +CI+CSG HRSLG HLS +RS ELD +W    
Sbjct: 470 IQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGPHLSRVRSLELD-DWPVEL 528

Query: 76  LRCMQ--VGGNASALW 89
            + M   V   A+++W
Sbjct: 529 RKVMSSIVNDLANSIW 544


>gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH
           domain 7 [Homo sapiens]
          Length = 663

 Score = 68.9 bits (167), Expect = 9e-12
 Identities = 34/76 (44%), Positives = 48/76 (63%), Gaps = 3/76 (3%)

Query: 16  LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQ 75
           ++++  N  C DC  +NP WAS+  GV +CI+CSG HRSLG  LS +RS ELD +W    
Sbjct: 447 IQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELD-DWPVEL 505

Query: 76  LRCMQVGGN--ASALW 89
            + M   GN  A+++W
Sbjct: 506 RKVMSSIGNDLANSIW 521


>gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
           and PH domain 9 [Homo sapiens]
          Length = 684

 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 33/76 (43%), Positives = 47/76 (61%), Gaps = 3/76 (3%)

Query: 16  LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQ 75
           ++++  N  C DC  +NP WAS+  GV +CI+CSG HRS G  LS +RS ELD +W    
Sbjct: 470 IQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELD-DWPVEL 528

Query: 76  LRCMQVGGN--ASALW 89
            + M   GN  A+++W
Sbjct: 529 RKVMSSIGNELANSIW 544


>gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
           and PH domain 10 [Homo sapiens]
          Length = 684

 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 33/76 (43%), Positives = 47/76 (61%), Gaps = 3/76 (3%)

Query: 16  LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQ 75
           ++++  N  C DC  +NP WAS+  GV +CI+CSG HRS G  LS +RS ELD +W    
Sbjct: 470 IQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTRLSRVRSLELD-DWPVEL 528

Query: 76  LRCMQVGGN--ASALW 89
            + M   GN  A+++W
Sbjct: 529 RKVMSSIGNELANSIW 544


>gi|7661880 centaurin beta1 [Homo sapiens]
          Length = 740

 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 32/58 (55%), Positives = 37/58 (63%)

Query: 12  IFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDS 69
           +  +++SV  N  C DC    P WASI  GV LCI CSG HRSLGVH S +RS  LDS
Sbjct: 407 VVAQVQSVDGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDS 464


>gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH
           domain 8 [Homo sapiens]
          Length = 663

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 33/76 (43%), Positives = 47/76 (61%), Gaps = 3/76 (3%)

Query: 16  LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQ 75
           ++++  N  C DC  +NP WAS+  GV +CI+CSG H SLG  LS +RS ELD +W    
Sbjct: 447 IQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHHSLGTRLSRVRSLELD-DWPVEL 505

Query: 76  LRCMQVGGN--ASALW 89
            + M   GN  A+++W
Sbjct: 506 RKVMSSIGNDLANSIW 521


>gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH
           domain 5 [Homo sapiens]
          Length = 686

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 33/76 (43%), Positives = 47/76 (61%), Gaps = 3/76 (3%)

Query: 16  LRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQ 75
           ++++  N  C D   +NP WAS+  GV +CI+CSG HRSLG  LS +RS ELD +W    
Sbjct: 470 IQNMRGNAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELD-DWPVEL 528

Query: 76  LRCMQVGGN--ASALW 89
            + M   GN  A+++W
Sbjct: 529 RKVMSSIGNDLANSIW 544


>gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
           isoform b [Homo sapiens]
          Length = 961

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 33/85 (38%), Positives = 46/85 (54%), Gaps = 1/85 (1%)

Query: 12  IFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNW 71
           I   ++ +  N VC DCGA +P+W S   G+  CI+CSG HR LGVH S ++S  LD   
Sbjct: 423 IISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLG 482

Query: 72  SWFQLRCMQVGGNASALWLDSCVVP 96
           +   L    + GNA    +  C +P
Sbjct: 483 TSELLLAKNI-GNAGFNEIMECCLP 506


>gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
           isoform a [Homo sapiens]
          Length = 1006

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 33/85 (38%), Positives = 46/85 (54%), Gaps = 1/85 (1%)

Query: 12  IFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNW 71
           I   ++ +  N VC DCGA +P+W S   G+  CI+CSG HR LGVH S ++S  LD   
Sbjct: 423 IISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLG 482

Query: 72  SWFQLRCMQVGGNASALWLDSCVVP 96
           +   L    + GNA    +  C +P
Sbjct: 483 TSELLLAKNI-GNAGFNEIMECCLP 506


>gi|6806913 centaurin, alpha 1 [Homo sapiens]
          Length = 374

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 38/106 (35%), Positives = 54/106 (50%), Gaps = 6/106 (5%)

Query: 1   MGDPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLS 60
           M    ++ +L + +R    P N  C DCGA +P WAS T GVF+C+ CSG HR++   +S
Sbjct: 1   MAKERRRAVLELLQR----PGNARCADCGAPDPDWASYTLGVFICLSCSGIHRNI-PQVS 55

Query: 61  FIRSTELDSNWSWFQLRCMQVGGNASALWLDSCVVPPLSPPPKEED 106
            ++S  LD+ W   Q+  M   GN +A       VP     P   D
Sbjct: 56  KVKSVRLDA-WEEAQVEFMASHGNDAARARFESKVPSFYYRPTPSD 100


>gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
           isoform b [Homo sapiens]
          Length = 894

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 48/174 (27%), Positives = 75/174 (43%), Gaps = 9/174 (5%)

Query: 12  IFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNW 71
           +   ++S P N  C DCGA +P+W S   GV  CI CSG HR LGV  S ++S  LD   
Sbjct: 419 LIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLG 478

Query: 72  SWFQLRCMQVGGNASALWLDSCVVPPLSPPPKEEDFFASH----VSPEVSDTAWASAIAE 127
               L  + +G  +    +++ +     P P  E    +     ++  V          E
Sbjct: 479 PSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFARRCTPE 538

Query: 128 P----SSLTSRPVETTLENNEGGQEQGPSVEGLNVPTKATLEVSSIIKKKPNQA 177
           P    +++ +R + + LE    GQ+ G  + G +      L V  +  K  NQA
Sbjct: 539 PQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEEL-VLHLAVKVANQA 591


>gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
           isoform a [Homo sapiens]
          Length = 903

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 48/174 (27%), Positives = 75/174 (43%), Gaps = 9/174 (5%)

Query: 12  IFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNW 71
           +   ++S P N  C DCGA +P+W S   GV  CI CSG HR LGV  S ++S  LD   
Sbjct: 428 LIAEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLG 487

Query: 72  SWFQLRCMQVGGNASALWLDSCVVPPLSPPPKEEDFFASH----VSPEVSDTAWASAIAE 127
               L  + +G  +    +++ +     P P  E    +     ++  V          E
Sbjct: 488 PSELLLALNMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFARRCTPE 547

Query: 128 P----SSLTSRPVETTLENNEGGQEQGPSVEGLNVPTKATLEVSSIIKKKPNQA 177
           P    +++ +R + + LE    GQ+ G  + G +      L V  +  K  NQA
Sbjct: 548 PQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEEL-VLHLAVKVANQA 600


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.126    0.359 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,388,679
Number of Sequences: 37866
Number of extensions: 854161
Number of successful extensions: 3196
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 68
Number of HSP's successfully gapped in prelim test: 76
Number of HSP's that attempted gapping in prelim test: 2933
Number of HSP's gapped (non-prelim): 281
length of query: 472
length of database: 18,247,518
effective HSP length: 106
effective length of query: 366
effective length of database: 14,233,722
effective search space: 5209542252
effective search space used: 5209542252
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.