Guide to the Human Genome
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Search of human proteins with 21450814

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21450814 ARKadia-like 1 isoform a [Homo sapiens]
         (404 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21450814 ARKadia-like 1 isoform a [Homo sapiens]                   789   0.0  
gi|56549656 ARKadia-like 1 isoform b [Homo sapiens]                   605   e-173
gi|37595553 ring finger protein 111 [Homo sapiens]                     97   3e-20
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    58   1e-08
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         45   9e-05
gi|50962882 G patch domain containing 8 [Homo sapiens]                 43   4e-04
gi|63176611 modulator of estrogen induced transcription isoform ...    42   8e-04
gi|217330641 IWS1 homolog [Homo sapiens]                               42   0.001
gi|168229156 NFKB activating protein [Homo sapiens]                    41   0.002
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    41   0.002
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       41   0.002
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]    41   0.002
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu...    40   0.003
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre...    40   0.003
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]                    40   0.003
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H...    40   0.004
gi|54633315 deoxynucleotidyltransferase, terminal, interacting p...    40   0.005
gi|27734775 hypothetical protein LOC286499 [Homo sapiens]              40   0.005
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo...    39   0.006
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           39   0.008
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           39   0.008
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]             39   0.008
gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]             39   0.008
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]    39   0.011
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]    39   0.011
gi|21361684 G patch domain containing 1 [Homo sapiens]                 39   0.011
gi|157738619 smoothelin-like 1 [Homo sapiens]                          39   0.011
gi|109809739 La ribonucleoprotein domain family, member 7 [Homo ...    38   0.019
gi|109809741 La ribonucleoprotein domain family, member 7 [Homo ...    38   0.019
gi|161016767 mucin 21 [Homo sapiens]                                   38   0.019

>gi|21450814 ARKadia-like 1 isoform a [Homo sapiens]
          Length = 404

 Score =  789 bits (2038), Expect = 0.0
 Identities = 404/404 (100%), Positives = 404/404 (100%)

Query: 1   MKMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLM 60
           MKMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLM
Sbjct: 1   MKMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLM 60

Query: 61  ELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQA 120
           ELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQA
Sbjct: 61  ELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQA 120

Query: 121 ETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHK 180
           ETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHK
Sbjct: 121 ETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHK 180

Query: 181 ERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDG 240
           ERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDG
Sbjct: 181 ERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDG 240

Query: 241 PPVVAHYDMSDTNSDPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAG 300
           PPVVAHYDMSDTNSDPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAG
Sbjct: 241 PPVVAHYDMSDTNSDPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAG 300

Query: 301 HLDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHG 360
           HLDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHG
Sbjct: 301 HLDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHG 360

Query: 361 SGTQYVSTRQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRKYLL 404
           SGTQYVSTRQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRKYLL
Sbjct: 361 SGTQYVSTRQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRKYLL 404


>gi|56549656 ARKadia-like 1 isoform b [Homo sapiens]
          Length = 343

 Score =  605 bits (1561), Expect = e-173
 Identities = 330/405 (81%), Positives = 334/405 (82%), Gaps = 63/405 (15%)

Query: 1   MKMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLM 60
           MKMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLM
Sbjct: 1   MKMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLM 60

Query: 61  ELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQA 120
           ELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQA
Sbjct: 61  ELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQA 120

Query: 121 ETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHK 180
           ETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHK
Sbjct: 121 ETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHK 180

Query: 181 ERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDG 240
           ERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSST                       
Sbjct: 181 ERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSST----------------------- 217

Query: 241 PPVVAHYDMSDTNSDPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEA- 299
                    S ++ D EV                              SG  + + AE  
Sbjct: 218 ---------SSSDDDEEV------------------------------SGSSKTITAEIP 238

Query: 300 GHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKH 359
           GHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKH
Sbjct: 239 GHLDPGFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKH 298

Query: 360 GSGTQYVSTRQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRKYLL 404
           GSGTQYVSTRQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRKYLL
Sbjct: 299 GSGTQYVSTRQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRKYLL 343


>gi|37595553 ring finger protein 111 [Homo sapiens]
          Length = 986

 Score = 97.1 bits (240), Expect = 3e-20
 Identities = 93/322 (28%), Positives = 145/322 (45%), Gaps = 70/322 (21%)

Query: 86  ESDSS-NHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSR 144
           ++DSS + C+ SPSSS H  DSDT++S E+ E S   +    +    S +    K  R+ 
Sbjct: 129 DNDSSFSDCLSSPSSSLHFGDSDTVTSDEDKEVSVRHSQTILNAKSRSHSARSHKWPRTE 188

Query: 145 SESETSTMAAKKNRQSSDKQNGRVAK--VKGH---RSQKHKERIRLLRQKREAAARKKYN 199
           +ES +  +  +     S  +     K  VK +   R+QK KERI + R+KRE  AR+KY 
Sbjct: 189 TESVSGLLMKRPCLHGSSLRRLPCRKRFVKNNSSQRTQKQKERILMQRKKREVLARRKYA 248

Query: 200 LL-QDSSTSDSDLTCDSSTS-SSDDDEEVSGSSKTITAEIPDGPPVVAHYDMSDTNSDPE 257
           LL   SS+S++DL+ +SS+S S++ +E+                                
Sbjct: 249 LLPSSSSSSENDLSSESSSSSSTEGEED-------------------------------- 276

Query: 258 VVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAGHLDPGFLASDKTSAGNA 317
                  L  +  + H N+                      +G +D   +  + +S    
Sbjct: 277 -------LFVSASENHQNNPA------------------VPSGSIDEDVVVIEASSTPQV 311

Query: 318 PLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAV 377
             NEEIN+ S+DSEVEIV V E  R    R  +  S S W  GS +     ++ ++ + +
Sbjct: 312 TANEEINVTSTDSEVEIVTVGESYR---SRSTLGHSRSHWSQGSSSHASRPQEPRNRSRI 368

Query: 378 TP--QQTWASPAEVVDLTLDED 397
           +   Q    + AEVVDLT+DED
Sbjct: 369 STVIQPLRQNAAEVVDLTVDED 390



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 27/104 (25%), Positives = 54/104 (51%), Gaps = 5/104 (4%)

Query: 53  SSMPCLLMELRRDSSESQLASTESDKPT----TGRVYESDSSNHCMLSPSSSGHLADSDT 108
           S +  ++  LR++++E    + + D+PT    T    ES +++  + + + S     SDT
Sbjct: 366 SRISTVIQPLRQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDT 425

Query: 109 LSSAEENEPSQ-AETAVEGDPSGVSGATVGRKSRRSRSESETST 151
            S+   ++PS  +ET+     +  +G ++G  SRR+ S + T T
Sbjct: 426 ASAVTSSQPSTVSETSATLTSNSTTGTSIGDDSRRTTSSAVTET 469


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 61/317 (19%), Positives = 127/317 (40%), Gaps = 15/317 (4%)

Query: 15  ESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLAST 74
           +S++   ++  +++   D S   +S    D  +DS+   S          DSS+S   S 
Sbjct: 592 DSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES----------DSSDSDSKSD 641

Query: 75  ESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGA 134
            SD  ++     SDSS+    S +SS     SD+  S++ +  S +  + +   S  S  
Sbjct: 642 SSDSNSSDSSDNSDSSD----SSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSN 697

Query: 135 TVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAA 194
           +         S+S++S  +   N  SSD  +   +      +              +++ 
Sbjct: 698 SSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSD 757

Query: 195 RKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDGPPVVAHYDMSDTNS 254
               +   DSS S        S++SSD ++  + S  + ++   D        D SD +S
Sbjct: 758 SSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSD-SS 816

Query: 255 DPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAGHLDPGFLASDKTSA 314
           D +  N  +   ++   + SNS    D+  +   S       +++ +      +SD +++
Sbjct: 817 DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS 876

Query: 315 GNAPLNEEINIASSDSE 331
            ++  + + N +S+ S+
Sbjct: 877 SDSSDSSDSNESSNSSD 893



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 68/328 (20%), Positives = 134/328 (40%), Gaps = 14/328 (4%)

Query: 16   SEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTE 75
            S++   +   +++   DGS + +S  + D    S    S          DSS+S  +S  
Sbjct: 833  SDSSNSSDSSDSSDSSDGS-DSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNS 891

Query: 76   SDKPTTGRVYESDSSNHCMLSPSS-SGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGA 134
            SD   +    +SDSS+    S SS S + +DS   S++ +N  S ++++   D S  S +
Sbjct: 892  SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNS-SDSSNSSDSSDSSDS 950

Query: 135  TVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQK--HKERIRLLRQKREA 192
            +    S  S   S +S  +   +  SSD  N   +      S      +          +
Sbjct: 951  SNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1010

Query: 193  AARKKYNLLQDSSTSDSDLTCDSSTS--------SSDDDEEVSGSSKTITAEIPDGPPVV 244
             +    N    S++SDS  + DSS S        SSD  +    S+ + +++  D     
Sbjct: 1011 DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070

Query: 245  AHYDMSDTNSDPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELN-AEAGHLD 303
               D SD++   E  +  +   ++   + S+S    D+  +  +S   +  N +++    
Sbjct: 1071 DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1130

Query: 304  PGFLASDKTSAGNAPLNEEINIASSDSE 331
                +SD +++ ++  + E + +S  S+
Sbjct: 1131 DSSDSSDSSNSSDSSDSSESSDSSDSSD 1158



 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 66/322 (20%), Positives = 124/322 (38%), Gaps = 15/322 (4%)

Query: 15   ESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLAST 74
            +S++   +    ++   D S   +S    D    S   SS        R DSS S  +S 
Sbjct: 817  DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSN-------RSDSSNSSDSSD 869

Query: 75   ESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGA 134
             SD   +    +S  SN    S  SS     SD+ SS   N    ++++   D S  S +
Sbjct: 870  SSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNS 929

Query: 135  TVGRKSRRSRSESETSTMAAKKNRQ----SSDKQNGRVAKVKGHRSQKHKERIRLLRQKR 190
            +    S  S + S++S  +   N      SSD  N   +      S    +         
Sbjct: 930  SDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNS--SDSSDSNSSDSSDSSNSSDSSD 987

Query: 191  EAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDGPPVVAHYDMS 250
             + +    +    S++SDS  + DSS SS+  D   S  S   +++  D        D S
Sbjct: 988  SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN-SSDSSDSSDSSDSSDSS 1046

Query: 251  DTNSDPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELN-AEAGHLDPGFLAS 309
            D++   +  N  +   ++   + S+S    D+  +  +S   +  N +++        +S
Sbjct: 1047 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSS 1106

Query: 310  DKTSAGNAPLNEEINIASSDSE 331
            D + + ++  + + + +S  S+
Sbjct: 1107 DSSDSSDSSDSSDSSNSSDSSD 1128



 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 64/319 (20%), Positives = 126/319 (39%), Gaps = 21/319 (6%)

Query: 15  ESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLAST 74
           +S     +S+   + + D S    S       +DS+  S           DSS+S  +S 
Sbjct: 553 DSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSD 612

Query: 75  ESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLS-SAEENEPSQAETAVEGDPSGVSG 133
            SD         SDSS+    S  S    +DSD+ S S++ N    ++ +   D S  S 
Sbjct: 613 SSD--------SSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSN 664

Query: 134 ATVGRKSRRSRSESETSTMA-AKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREA 192
           ++    S  S   S +S  + +  +  SSD  N   +      S              ++
Sbjct: 665 SSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDS---------DSSDS 715

Query: 193 AARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDGPPVVAHYDMSDT 252
           +     N     S++ SD +  S++S S D  + S SS   +++  D        D SD+
Sbjct: 716 SDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSD--SSDSSDSSNSSDSSDSSDS 773

Query: 253 NSDPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAGHLDPGFLASDKT 312
           +   +  N  +   ++   + S+S    D+  +  +S   +  ++++ +      +SD +
Sbjct: 774 SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833

Query: 313 SAGNAPLNEEINIASSDSE 331
            + N+  + + + +S  S+
Sbjct: 834 DSSNSSDSSDSSDSSDGSD 852



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 63/318 (19%), Positives = 120/318 (37%), Gaps = 30/318 (9%)

Query: 15  ESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLAST 74
           +S +   +   +++   + S   +S    D    S+   S          DSS S  +S 
Sbjct: 644 DSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSD 703

Query: 75  ESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGA 134
            SD   +     SDSSN       SS     SD+ +S++ ++ S +  + +   S  S  
Sbjct: 704 SSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSN 763

Query: 135 TVGRKSRRSRSESETSTMAAKKN--RQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREA 192
           +         S+S  S+ ++  N    SSD  +   +    + S                
Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDS----------- 812

Query: 193 AARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDGPPVVAHYDMSDT 252
                     DSS SDS  + DSS +SSD  +  + S  + +++  DG         SD+
Sbjct: 813 ---------SDSSDSDSSNSSDSS-NSSDSSDSSNSSDSSDSSDSSDGSD-------SDS 855

Query: 253 NSDPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAGHLDPGFLASDKT 312
           ++  +  N  +   ++     S+S    D+  +  +S   +  N+          +SD +
Sbjct: 856 SNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSS 915

Query: 313 SAGNAPLNEEINIASSDS 330
            + N+  + E + +S +S
Sbjct: 916 DSSNSSDSSESSNSSDNS 933



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 61/317 (19%), Positives = 123/317 (38%), Gaps = 10/317 (3%)

Query: 16   SEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTE 75
            S++   +   +++   D S   +S    D    S    S          DSS+S  +S  
Sbjct: 983  SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042

Query: 76   SDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQA-ETAVEGDPSGVSGA 134
            SD   +    +S +S+    S  SS     SD+  S++ +E S + +++   D S  S +
Sbjct: 1043 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDS 1102

Query: 135  TVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAA 194
            +    S  S   S++S   +  +  SSD  +   +    + S           +  +++ 
Sbjct: 1103 SDSSDSSDSSDSSDSSD--SSNSSDSSDSSDSSDSSDSSNSSDSSDSS-----ESSDSSD 1155

Query: 195  RKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDGPPVVAHYDMSDTNS 254
                +   DSS S        S++SSD  +    S  + +++  D        D SD++ 
Sbjct: 1156 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1215

Query: 255  DPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAGHLDPGFLASDKTSA 314
              +  +  +   ++   E S+S    D+  +  +S   +  ++     D    +  ++ +
Sbjct: 1216 SSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKS 1275

Query: 315  GNAPLNEEINIASSDSE 331
            GN   N   + + SDSE
Sbjct: 1276 GNG--NNNGSDSDSDSE 1290



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 57/267 (21%), Positives = 118/267 (44%), Gaps = 19/267 (7%)

Query: 75  ESDKPTTGR-------VYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGD 127
           ++DK  +G+          SDSSN    S SS    +DS++ S ++ ++   ++++ + D
Sbjct: 536 DNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSS-DSD 594

Query: 128 PSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLR 187
            S  S ++    S  S   S++S  +  K+  S  + +   +  K   S  +        
Sbjct: 595 SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNS 654

Query: 188 QKREAAARKKYNLLQDSS-TSDSDLTCDSSTSS-SDDDEEVSGSSKTITAEIPDGPPVVA 245
              +++     +   DSS +SDS  + DSS SS S D  + S SS++  +          
Sbjct: 655 DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSD 714

Query: 246 HYDMSDTN-SDPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAGHLDP 304
             D S++N SD +  N      ++   + SNS    D+  +  +S   +  ++++ +   
Sbjct: 715 SSDSSNSNSSDSDSSN------SSDSSDSSNSSDSSDSSDSSNSSDSSD--SSDSSNSSD 766

Query: 305 GFLASDKTSAGNAPLNEEINIASSDSE 331
              +SD + + ++  + + N +S+ S+
Sbjct: 767 SSDSSDSSDSSDSSNSSDSNDSSNSSD 793



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 48/249 (19%), Positives = 94/249 (37%), Gaps = 1/249 (0%)

Query: 16   SEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTE 75
            S++   +    ++   D S   +S    D    S    S          DSS+S  +S  
Sbjct: 1046 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDS 1105

Query: 76   SDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQA-ETAVEGDPSGVSGA 134
            SD   +    +S  S++   S  SS     SD+ +S++ ++ S++ +++   D S  S +
Sbjct: 1106 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDS 1165

Query: 135  TVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAA 194
            +    S  S   S +S  +   +   S   +          S    +          + +
Sbjct: 1166 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1225

Query: 195  RKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDGPPVVAHYDMSDTNS 254
                +  + S +SDS  + DSS SS   D   S  S + + +  D      + + + ++S
Sbjct: 1226 SDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDS 1285

Query: 255  DPEVVNVDN 263
            D +    D+
Sbjct: 1286 DSDSEGSDS 1294



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 54/280 (19%), Positives = 110/280 (39%), Gaps = 51/280 (18%)

Query: 63  RRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAET 122
           + DS + +  S++SD         SDSSN    S SS    +DS++ S ++ ++   +++
Sbjct: 539 KSDSGKGKSDSSDSDS--------SDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDS 590

Query: 123 AVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKER 182
           + + D S  S ++    S  S   S++S  +  K+  S  + +   +  K   S  +   
Sbjct: 591 S-DSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNS-- 647

Query: 183 IRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSS-----------SDDDEEVSGSSK 231
                                S +SD+  + DSS SS           SD       S+ 
Sbjct: 648 ---------------------SDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNS 686

Query: 232 TITAEIPDGPPVVAHYDMSDTNSDPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGL 291
           + +++  D        D SD++      + D+  + +   + SNS    D+  +  +S  
Sbjct: 687 SDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDS 746

Query: 292 LEELNAEAGHLDPGFLASDKTSAGNAPLNEEINIASSDSE 331
            +  N+          +SD + + N+  + + + +S  S+
Sbjct: 747 SDSSNSSD--------SSDSSDSSNSSDSSDSSDSSDSSD 778



 Score = 36.6 bits (83), Expect = 0.042
 Identities = 51/246 (20%), Positives = 100/246 (40%), Gaps = 29/246 (11%)

Query: 98  SSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKN 157
           S++G  ++SD   S + ++ S     ++GD    S  + G     S S++ +S+      
Sbjct: 439 SNTGSDSNSDGYDSYDFDDKS-----MQGDDPNSSDESNGNDDANSESDNNSSSRGDASY 493

Query: 158 RQSSDKQNGRVAKVKG------------HRSQKHKERIRLLRQKREAAARKKYNLLQDSS 205
                K NG  +  KG            + S  +           ++ + K  +   DS 
Sbjct: 494 NSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSD 553

Query: 206 TSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDGPPVVAHYDMSDTNSDPEVVNVDNLL 265
           +SDS  + DSS SS  D  + + SS + +++           D SD +SD +  +  N  
Sbjct: 554 SSDSSNSSDSSDSSDSDSSDSNSSSDSDSSD----------SDSSD-SSDSDSSDSSNSS 602

Query: 266 AAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAGHLDPGFLASDKTSAGNAPLNEEINI 325
            ++   + S+S    D+  +   S   E  ++++        ++   S+ N+  ++  N 
Sbjct: 603 DSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNS 662

Query: 326 A-SSDS 330
           + SSDS
Sbjct: 663 SNSSDS 668



 Score = 35.4 bits (80), Expect = 0.093
 Identities = 59/292 (20%), Positives = 112/292 (38%), Gaps = 34/292 (11%)

Query: 13  LIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLA 72
           +++ + P  A    +   ED  +E   + + +    +  I+S        R  + E+++ 
Sbjct: 178 VVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSK-------RNGTKEAEVT 230

Query: 73  STESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVS 132
                 P TG     D+S+    SPS +G   D D  S  +E+E +        +  G  
Sbjct: 231 ------PGTGEDAGLDNSDG---SPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQE 281

Query: 133 GATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREA 192
           G   G++     S  + S      + +  +  +  V   K  +S+++   I      +  
Sbjct: 282 GQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRI 341

Query: 193 AARKKYNLLQDSSTSDSDLTCDSST----SSSDDDEEVSGSS---KTITAEI---PDGPP 242
              +K N  ++S   ++ +T +S T     S D   E+ G S   + IT E+    +G  
Sbjct: 342 EDTQKLN-HRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKE 400

Query: 243 VVAHYDM----SDTNSDPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSG 290
               + M     +  +  EVVN++         E  N VG  +TG+   + G
Sbjct: 401 DKGQHGMILGKGNVKTQGEVVNIE---GPGQKSEPGNKVGHSNTGSDSNSDG 449



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 28/117 (23%), Positives = 45/117 (38%)

Query: 16   SEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLASTE 75
            S++   +   +++   D S   +S    D    S    S          DS+ES  +S  
Sbjct: 1181 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDS 1240

Query: 76   SDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVS 132
            SD   +    +S  S+    S S S   +DS + S    N  S +++  EG  S  S
Sbjct: 1241 SDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHS 1297


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 37/147 (25%), Positives = 59/147 (40%), Gaps = 10/147 (6%)

Query: 96   SPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAK 155
            S SSS   + S + SS+  +  S+ E   EGD +G  G   G ++  + S    S  ++ 
Sbjct: 2557 SESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSS 2616

Query: 156  KNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDS 215
             +  SS   +   +      S               +++    +    SS+S S  +  S
Sbjct: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSS----------SSSSSSSSSSSSSSSSSSSSSSSS 2666

Query: 216  STSSSDDDEEVSGSSKTITAEIPDGPP 242
            S+SSS  DE+ S SS    A  P   P
Sbjct: 2667 SSSSSTTDEDSSCSSDDEAAPAPTAGP 2693



 Score = 30.4 bits (67), Expect = 3.0
 Identities = 23/96 (23%), Positives = 41/96 (42%), Gaps = 2/96 (2%)

Query: 66   SSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVE 125
            SS S  +S+ S   ++     S SS+    S SSS   + S + SS+  +  +  +++  
Sbjct: 2621 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCS 2680

Query: 126  GDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSS 161
             D       T G  ++ +      +T  A K R S+
Sbjct: 2681 SDDEAAPAPTAGPSAQAALPTK--ATKQAGKARPSA 2714


>gi|50962882 G patch domain containing 8 [Homo sapiens]
          Length = 1502

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 39/187 (20%), Positives = 71/187 (37%), Gaps = 30/187 (16%)

Query: 73  STESDKPTTGRVYE-SDSSNHCMLSPSSSGHLADSDTLSSAEEN---------------- 115
           S  S K  +G+ +       H   S     H AD++  SS  E+                
Sbjct: 661 SLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNK 720

Query: 116 --EPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKG 173
              P+ +E   + +P G       R+ RR++ +S+  ++ A++       + G  +  + 
Sbjct: 721 SSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQD 780

Query: 174 HRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTS-----------SSDD 222
           H  +KHK  +     +R A  ++       S  S  D   D ++S           S ++
Sbjct: 781 HGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEE 840

Query: 223 DEEVSGS 229
           +EE SGS
Sbjct: 841 EEEDSGS 847



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 37/148 (25%), Positives = 57/148 (38%), Gaps = 19/148 (12%)

Query: 87  SDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGV----SGATVGRK--- 139
           S  S+H    PSS    +D  +     +  PSQ     E + SG     S +  GR+   
Sbjct: 804 SSRSSH-RSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSS 862

Query: 140 ---SRRSRSESETS----TMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREA 192
              SRRS S S  +    +  +++   S D  +    + + H  + H          +  
Sbjct: 863 HRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHR 922

Query: 193 AARKKYNLLQDSSTSDSDLTCDSSTSSS 220
           + R KY+    SS  D  L+C  S S S
Sbjct: 923 SKRHKYS----SSDDDYSLSCSQSRSRS 946


>gi|63176611 modulator of estrogen induced transcription isoform a
           [Homo sapiens]
          Length = 1034

 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 61/251 (24%), Positives = 104/251 (41%), Gaps = 36/251 (14%)

Query: 9   KVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSE 68
           +  ELIE+E       ++  KE+  S E+E+Q  +D     T +++      E  +D + 
Sbjct: 150 RAHELIEAEGI-----EDIEKEDIESQEIEAQEGED----DTFLTAQDGEEEENEKDIAG 200

Query: 69  SQLASTESDKP--TTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEG 126
           S   + E  KP  + G + E+D + H  +   ++   A+ D +S        QAE A+  
Sbjct: 201 SGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHTTVKEAEDDNISVT-----IQAEDAITL 255

Query: 127 DPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERI--- 183
           D  G      G+  + + SE+           QS +K++        H+  K ++ +   
Sbjct: 256 DFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGD 315

Query: 184 ------RLLRQKREAAARKKYNLLQDSST--------SDSDLTCDSSTSSSDD---DEEV 226
                 R   +K E+  ++K  L +  S+        S S  + DS TSS DD       
Sbjct: 316 PVEKEARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSST 375

Query: 227 SGSSKTITAEI 237
           SGSS + T  I
Sbjct: 376 SGSSGSSTKNI 386


>gi|217330641 IWS1 homolog [Homo sapiens]
          Length = 819

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 56/262 (21%), Positives = 104/262 (39%), Gaps = 55/262 (20%)

Query: 15  ESEAPPKASEQETAKEEDGSVELES----QVQKDGVADSTVISSMPCLLMELRRDSSE-- 68
           ESE PP+    ++  EE     +      ++ K  V+DS   S  P        ++ E  
Sbjct: 186 ESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSE--SEEPPRHQASDSENEELP 243

Query: 69  -SQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENE------PSQAE 121
             +++ +ES+ P   R   SDS N  +  P  S   ++    + A ++E      P  ++
Sbjct: 244 KPRISDSESEDPP--RHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSD 301

Query: 122 TAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNR----------------------Q 159
           +  EG   G +  +    + R + + E+   + ++N+                       
Sbjct: 302 SESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFH 361

Query: 160 SSD--KQNGRVAKVKGHRSQKHKERIRLLRQK---------REAAARKKYNLLQDSSTSD 208
           SSD  ++  +  K+     +K  E  ++ ++K          E A+ KK  ++ D+  SD
Sbjct: 362 SSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSD 421

Query: 209 SDLTCDSS-----TSSSDDDEE 225
           SD   D S     T +SD +EE
Sbjct: 422 SDAVSDKSGKREKTIASDSEEE 443


>gi|168229156 NFKB activating protein [Homo sapiens]
          Length = 415

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 42/163 (25%), Positives = 72/163 (44%), Gaps = 22/163 (13%)

Query: 59  LMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPS 118
           L++  R+ S  Q   +E +     R+ E  +     LSP +     DSD  +  E+ EP 
Sbjct: 117 LLDKEREESLRQKRLSERE-----RIGELGAPEVWGLSPKNPE--PDSDEHTPVEDEEPK 169

Query: 119 QAETAV---EGDPSGVSGATVGRKSRRSRSES---------ETSTMAAKKNRQSSDKQNG 166
           ++ T+    E +    S  +  R  +R + +S         E S   +     SSD+ N 
Sbjct: 170 KSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNK 229

Query: 167 RVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDS 209
           R AK    + +K K R +  ++KR   +RK+ +   DSS+ +S
Sbjct: 230 RRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESS---DSSSKES 269



 Score = 37.0 bits (84), Expect = 0.032
 Identities = 41/169 (24%), Positives = 68/169 (40%), Gaps = 13/169 (7%)

Query: 63  RRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSS---GHLADSDTLSSAEENEPSQ 119
           R  S  S+  S   ++P+  R     S++  +   S S   G      +L   E  E  +
Sbjct: 68  RNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLR 127

Query: 120 AETAVEGDPSGVSGATV--GRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQ 177
            +   E +  G  GA    G   +    +S+  T    +  + S        + K  +S 
Sbjct: 128 QKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSS 187

Query: 178 KHKERIRLLRQKREAAAR-KKYNLLQDSSTSDSDLTCDSSTSSSDDDEE 225
           + KER +  R+K+ +  + KKY+        DSD   DS T SSD+D +
Sbjct: 188 RSKERSKKRRKKKSSKRKHKKYS-------EDSDSDSDSETDSSDEDNK 229


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 36/165 (21%), Positives = 68/165 (41%), Gaps = 13/165 (7%)

Query: 15  ESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLAST 74
           + EAP K +          +V  +S   K   A    +     LL   + DSS S+  S+
Sbjct: 373 DDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTR-KADSSSSEEESS 431

Query: 75  ESDKPTTGRVYESDS---------SNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVE 125
            S++  T ++  +           S     +P  S   +     SS+EE E   +++AV+
Sbjct: 432 SSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVK 491

Query: 126 GDPSGVSGATVGRK---SRRSRSESETSTMAAKKNRQSSDKQNGR 167
             P  V+G     K   +++ ++ES  S+ +   + +  +K  G+
Sbjct: 492 KKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGK 536



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 46/221 (20%), Positives = 82/221 (37%), Gaps = 43/221 (19%)

Query: 11  EELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQ 70
           ++ +E + P ++SE +++ E D S E E +     V         P             +
Sbjct: 310 KKAVEKQQPVESSE-DSSDESDSSSEEEKKPPTKAVVSKATTKPPPA-----------KK 357

Query: 71  LASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSG 130
            A + SD        +SDSS         +G   +S    +     P+    A    P G
Sbjct: 358 AAESSSDSS------DSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVG 411

Query: 131 VSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKR 190
                + RK+  S SE E+S+                        S++ K +  +   K 
Sbjct: 412 GGQKLLTRKADSSSSEEESSS------------------------SEEEKTKKMVATTKP 447

Query: 191 EAAARKKYNL-LQDSSTSDSDLTCDSSTSSSDDDEEVSGSS 230
           +A A+   +L  + +     D + DS +SSS+++EE +  S
Sbjct: 448 KATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKS 488



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 38/180 (21%), Positives = 75/180 (41%), Gaps = 14/180 (7%)

Query: 60  MELRRDSS-ESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPS 118
           +E   DSS ES  +S E  KP T  V    ++       ++      SD+ SS ++  PS
Sbjct: 319 VESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPS 378

Query: 119 QAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKK-----NRQSSDKQNGRVAKVKG 173
           +        P+G +  +  + +  ++S +     A K+      +  + K +   ++ + 
Sbjct: 379 K--------PAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEES 430

Query: 174 HRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTI 233
             S++ K +  +   K +A A+   +L    +   S  +   S SSS ++EE   S   +
Sbjct: 431 SSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAV 490



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 55/239 (23%), Positives = 91/239 (38%), Gaps = 49/239 (20%)

Query: 63  RRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENE----PS 118
           ++D++ S L    S    + +V E     +  ++  +    + SD+  S+EE E    P 
Sbjct: 42  QQDANASSLLDIYSFWLKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPP 101

Query: 119 QAETAVEGDPSGVSGATVGRKSRRSRSESETS-----------------------TMAAK 155
             + AV     G+       K+  S S  E+S                         A  
Sbjct: 102 AKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPP 161

Query: 156 KNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREA------AARKKYNLLQDSSTSDS 209
           K  +SSD  +   ++ +  ++QK K     ++ + +A      AA K  N    SS+S S
Sbjct: 162 KKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSS 221

Query: 210 DLTCDSSTSSSDDDEEVSGSS--------KTITAEIP---DGPPVVAHYDMSDTNSDPE 257
                SS+SSSDD EE   ++        K + A+ P      P        D++SD E
Sbjct: 222 -----SSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEE 275


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 40/221 (18%), Positives = 84/221 (38%), Gaps = 10/221 (4%)

Query: 14  IESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVI-SSMPCLLMELRRDSSESQLA 72
           +E +      E+   +EE     L+  +++    D T+  +S+      ++ D++E++  
Sbjct: 88  VEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETT 147

Query: 73  STESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVS 132
             E    +    YE + +     S   +      +     +E E  + E    G   G +
Sbjct: 148 EKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGS-IGEN 206

Query: 133 GATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKH--------KERIR 184
              V  + + + S+ ET  M+ K  + SS++      + +G     H        KER  
Sbjct: 207 QVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAE 266

Query: 185 LLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEE 225
             R + EA  R++    QD   +D     ++   ++  + E
Sbjct: 267 AERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERE 307



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 36/194 (18%), Positives = 69/194 (35%), Gaps = 13/194 (6%)

Query: 1   MKMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLM 60
           +K E+     +E    EA  KA+ QE  + E    E   + +K    +   I        
Sbjct: 280 IKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAA 339

Query: 61  ELR-RDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQ 119
           E R R   E + A+ E  +        ++              + +       EE + + 
Sbjct: 340 EERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAM 399

Query: 120 AETAVEGDP--SGVSGATVGRKSR----------RSRSESETSTMAAKKNRQSSDKQNGR 167
            ET ++G+     + G  V  K            + + E + + + AK+ +   DK   +
Sbjct: 400 QETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFK 459

Query: 168 VAKVKGHRSQKHKE 181
             ++K  + +K KE
Sbjct: 460 KEEIKDEKIKKDKE 473


>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
          Length = 1462

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 53/260 (20%), Positives = 107/260 (41%), Gaps = 25/260 (9%)

Query: 2    KMEEAVGKVEELIESE-APPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLM 60
            K  E+   ++   +SE +  +A++    KE+ G +E     Q+    +    S   C   
Sbjct: 797  KYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHS 856

Query: 61   ELR----RDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENE 116
            + R      S   +  S    K   G  ++S+S++   ++ +S      S      E   
Sbjct: 857  KKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATS 916

Query: 117  PSQAETA---VEGDPSGVS----------GATVGRKSRRSRSESETSTMAAKKNRQSSDK 163
             S++E +   ++  P+  S          GA    K R S S+SE S   ++ NR    K
Sbjct: 917  DSESEVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQK 976

Query: 164  -QNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNL-----LQDSSTSDSDLTCDSST 217
             ++G    +K   ++K KE+++  + K+  A ++K        L+     + ++  D   
Sbjct: 977  HKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPLEFGEEEEEEID-DKQV 1035

Query: 218  SSSDDDEEVSGSSKTITAEI 237
            +    +++VS +++TI   I
Sbjct: 1036 TQESKEKKVSENNETIKDNI 1055



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 46/204 (22%), Positives = 81/204 (39%), Gaps = 26/204 (12%)

Query: 30  EEDGSVELESQVQKDGVADSTVISSMPCLLMELR-RDSSESQLASTESDKPTTGRVYESD 88
           +E GS     + +K+  +D +  S       E   R  S S  + + S   T  R   S 
Sbjct: 656 KETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASS 715

Query: 89  SSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESE 148
            S     SPSS  H    +  S   +   S + T++  D          R  RR RS  +
Sbjct: 716 HSRS--RSPSSRSH--SRNKYSDHSQCSRSSSYTSISSDDGR-------RAKRRLRSSGK 764

Query: 149 TSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSD 208
            ++++ KK+  SS+       K    +  K ++R   +R+  E+ +   Y       +SD
Sbjct: 765 KNSVSHKKHSSSSE-------KTLHSKYVKGRDRSSCVRKYSESRSSLDY-------SSD 810

Query: 209 SDLTCDSSTSSSDDDEEVSGSSKT 232
           S+ +   +T S+ + E+     +T
Sbjct: 811 SEQSSVQATQSAQEKEKQGQMERT 834



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 56/243 (23%), Positives = 96/243 (39%), Gaps = 27/243 (11%)

Query: 63  RRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAET 122
           R  SS S   +  SD     R     SS++  +S S  G  A     SS ++N  S  + 
Sbjct: 720 RSPSSRSHSRNKYSDHSQCSR-----SSSYTSIS-SDDGRRAKRRLRSSGKKNSVSHKKH 773

Query: 123 AVEGDPS-------GVSGATVGRKSRRSRS------ESETSTMAAKKNRQSSDKQNGRVA 169
           +   + +       G   ++  RK   SRS      +SE S++ A ++ Q  +KQ G++ 
Sbjct: 774 SSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQ-GQME 832

Query: 170 KVKGHRSQKHKERIRLLRQKREAAARKKYNL---LQDSSTSDSDLTCDSSTSSSDDDEEV 226
           +   H  Q+        + +RE    KK  L   L D   + S     +   S  D E  
Sbjct: 833 RT--HNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESN 890

Query: 227 SGSSKTITAEIPDGPPVVAHYDMSDTNSDPEVVNVDNLLAAAVVQEHSNSVGGQDTGATW 286
           S    T  ++    P        + ++S+ EV  + ++      +  +N+    D GA W
Sbjct: 891 SERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEI-HIKVKPTTKSSTNTSLPDDNGA-W 948

Query: 287 RTS 289
           ++S
Sbjct: 949 KSS 951


>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
           precursor [Homo sapiens]
          Length = 513

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 53/241 (21%), Positives = 95/241 (39%), Gaps = 29/241 (12%)

Query: 21  KASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSS-ESQLASTESDKP 79
           + SE++   E D +  +E +V+ D   +S   +S    L + RRDS  +SQ  S E+   
Sbjct: 272 RISEEDDRSELDDNNTME-EVKSDSTENS---NSRDTGLSQPRRDSKGDSQEDSKENLSQ 327

Query: 80  TTGRVYE---SDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGA-- 134
              +  +   S+SS    LS   +   +  + +S +  + P    + VE      S    
Sbjct: 328 EESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEED 387

Query: 135 ---TVGRKSRRSRSE------SETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRL 185
              T+      SR E      SE+   + +      D+ +     ++ H S         
Sbjct: 388 SSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAES----- 442

Query: 186 LRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSG---SSKTITAEIPDGPP 242
             Q  E+ + +  +  QDSS S  D     S SSS++D ++      S+ +T +     P
Sbjct: 443 --QSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVDAYHNKP 500

Query: 243 V 243
           +
Sbjct: 501 I 501



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 36/158 (22%), Positives = 62/158 (39%), Gaps = 11/158 (6%)

Query: 15  ESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLAST 74
           ES      S QE + E    V  ES+        S V             DSSE   + T
Sbjct: 339 ESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDS-------DSSEEDSSHT 391

Query: 75  ESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGA 134
            S   +  R  ++DS +   L+ S     +  D  SS++E   S + +A        S  
Sbjct: 392 LSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEE 451

Query: 135 TVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVK 172
                   SRS+ ++++  +K    SS +++G++  ++
Sbjct: 452 DDSDSQDSSRSKEDSNSTESK----SSSEEDGQLKNIE 485


>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
           precursor [Homo sapiens]
          Length = 497

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 53/241 (21%), Positives = 95/241 (39%), Gaps = 29/241 (12%)

Query: 21  KASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSS-ESQLASTESDKP 79
           + SE++   E D +  +E +V+ D   +S   +S    L + RRDS  +SQ  S E+   
Sbjct: 256 RISEEDDRSELDDNNTME-EVKSDSTENS---NSRDTGLSQPRRDSKGDSQEDSKENLSQ 311

Query: 80  TTGRVYE---SDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGA-- 134
              +  +   S+SS    LS   +   +  + +S +  + P    + VE      S    
Sbjct: 312 EESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEED 371

Query: 135 ---TVGRKSRRSRSE------SETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRL 185
              T+      SR E      SE+   + +      D+ +     ++ H S         
Sbjct: 372 SSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAES----- 426

Query: 186 LRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSG---SSKTITAEIPDGPP 242
             Q  E+ + +  +  QDSS S  D     S SSS++D ++      S+ +T +     P
Sbjct: 427 --QSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVDAYHNKP 484

Query: 243 V 243
           +
Sbjct: 485 I 485



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 36/158 (22%), Positives = 62/158 (39%), Gaps = 11/158 (6%)

Query: 15  ESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSESQLAST 74
           ES      S QE + E    V  ES+        S V             DSSE   + T
Sbjct: 323 ESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDS-------DSSEEDSSHT 375

Query: 75  ESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGA 134
            S   +  R  ++DS +   L+ S     +  D  SS++E   S + +A        S  
Sbjct: 376 LSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEE 435

Query: 135 TVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVK 172
                   SRS+ ++++  +K    SS +++G++  ++
Sbjct: 436 DDSDSQDSSRSKEDSNSTESK----SSSEEDGQLKNIE 469


>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
          Length = 1163

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 48/178 (26%), Positives = 72/178 (40%), Gaps = 25/178 (14%)

Query: 69  SQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDP 128
           SQ    E  +  TG  Y +D+S     S ++ G   DS T+    E+   + ++  + D 
Sbjct: 499 SQGYKKEGREQGTGNSY-TDTSGPKETSSATPGR--DSKTIQKGSESGRGRQKSPAQSD- 554

Query: 129 SGVSGATVGRKSRRS-------------RSESETSTMAAKKNRQSSDKQNGRVAKVKGHR 175
           S     TVG+K  +              + ESET    A     S  K     A  KG R
Sbjct: 555 STTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHK-----AATKGSR 609

Query: 176 SQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLT-CDSSTSSSDDDEEVSGSSKT 232
               K+  +     R  A +KKY     SS    ++   D+S+S SD+ E +  SS+T
Sbjct: 610 KPNIKKESK--SSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQT 665



 Score = 28.9 bits (63), Expect = 8.7
 Identities = 34/106 (32%), Positives = 48/106 (45%), Gaps = 17/106 (16%)

Query: 19  PPKASEQETAKEE-DGSVELESQVQKDGV--ADSTVISSMPCLLMELRRDSSESQLASTE 75
           P K S    +K      ++L S    DG    D T+  S P          S S+ +   
Sbjct: 367 PSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTP---------GSNSEPSHHN 417

Query: 76  SDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSS-AEENEPSQA 120
           S+     R    DSS+H   S SSSG  ++S++ SS +E NEPSQ+
Sbjct: 418 SEGADNSR---DDSSSHSG-SESSSGSDSESESSSSDSEANEPSQS 459



 Score = 28.9 bits (63), Expect = 8.7
 Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 15/103 (14%)

Query: 20  PKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSES---QLASTES 76
           PK +E+  A+E  G +++ES+   D      + SSMP    +     S     +  S  S
Sbjct: 567 PKKAEKAAAEEPRGGLKIESETPVD------LASSMPSSRHKAATKGSRKPNIKKESKSS 620

Query: 77  DKPTT-GRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPS 118
            +PT   + Y+S S      S   S  + ++DT SS  +   S
Sbjct: 621 PRPTAEKKKYKSTSK-----SSQKSREIIETDTSSSDSDESES 658


>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
           sapiens]
          Length = 1094

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 29/128 (22%), Positives = 58/128 (45%), Gaps = 5/128 (3%)

Query: 110 SSAEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVA 169
           S +EE E S   ++   D    SG+  G +   S  E +++  +++ +    D ++GR +
Sbjct: 677 SESEEEEDSSDSSS---DSESESGSESGEQGE-SGEEGDSNEDSSEDSSSEQDSESGRES 732

Query: 170 KVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSS-SDDDEEVSG 228
            ++  R+ K   + +      +     + +   DSS  +S    DSS+ S S+ + E   
Sbjct: 733 GLENKRTAKRNSKAKGKSDSEDGEKENEKSKTSDSSNDESSSIEDSSSDSESESEPESES 792

Query: 229 SSKTITAE 236
            S+ +T E
Sbjct: 793 ESRRVTKE 800



 Score = 34.3 bits (77), Expect = 0.21
 Identities = 30/146 (20%), Positives = 53/146 (36%), Gaps = 10/146 (6%)

Query: 65  DSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAV 124
           DSS    + + S+    G   E   SN      SSS   ++S   S  E    ++  +  
Sbjct: 687 DSSSDSESESGSESGEQGESGEEGDSNEDSSEDSSSEQDSESGRESGLENKRTAKRNSKA 746

Query: 125 EGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIR 184
           +G      G     KS+ S S ++ S+     +  S  +             +   E  R
Sbjct: 747 KGKSDSEDGEKENEKSKTSDSSNDESSSIEDSSSDSESES----------EPESESESRR 796

Query: 185 LLRQKREAAARKKYNLLQDSSTSDSD 210
           + ++K +   + +  L +D S  D D
Sbjct: 797 VTKEKEKKTKQDRTPLTKDVSLLDLD 822


>gi|54633315 deoxynucleotidyltransferase, terminal, interacting
           protein 2 [Homo sapiens]
          Length = 756

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 66/281 (23%), Positives = 109/281 (38%), Gaps = 16/281 (5%)

Query: 64  RDSSESQLAS-TESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAET 122
           R +S  Q  S +E +KP        D  +H     SS   L   +  +     E  Q   
Sbjct: 242 RQTSHLQARSLSEINKPNFYNNDFDDDFSH----RSSENILTVHEQANVESLKETKQNCK 297

Query: 123 AVEGDPSGVS--GATVGRKSRRSRSESETSTMAAKK--NRQSSDKQNGRVAKVKGHRSQK 178
            ++ D +G++  G  +  KS + ++ SE    + ++  +++ S  QN     V  H +  
Sbjct: 298 DLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSV--HSNLN 355

Query: 179 HKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEE---VSGSSKTITA 235
            +  ++ L Q        ++N  + S    SDLT       SDD+EE   +S S    + 
Sbjct: 356 SEAVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSE 415

Query: 236 EIPDGPPVVAHYDMSDTNSDPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEEL 295
              D       Y  +   S  +  +V  +L++   Q+  NS   +DT      SG  E L
Sbjct: 416 GNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESL 475

Query: 296 NAEAGHL--DPGFLASDKTSAGNAPLNEEINIASSDSEVEI 334
           + + G L  D      D T   +A  N  +      SEV I
Sbjct: 476 SGDTGSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAI 516


>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
          Length = 248

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 35/140 (25%), Positives = 65/140 (46%), Gaps = 10/140 (7%)

Query: 65  DSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAV 124
           DSS S   S + +K    R       N    S  SS H ++S++  S ++ + S+ ET  
Sbjct: 112 DSSSSSSDSEDEEKKQGKR--RKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEK 169

Query: 125 EGDPSGVSG----ATVGRKSRRSRSESETS---TMAAKKNRQSSDKQNGRVAKVKGHRSQ 177
           E D   +S     +    K   S S SE+     + AKK R+  +++  +  KVK  + +
Sbjct: 170 EKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAK-EKVKKKKKK 228

Query: 178 KHKERIRLLRQKREAAARKK 197
           +HK+  +  ++K  ++ + +
Sbjct: 229 QHKKHSKKKKKKSGSSHKSR 248



 Score = 32.7 bits (73), Expect = 0.60
 Identities = 37/160 (23%), Positives = 68/160 (42%), Gaps = 21/160 (13%)

Query: 66  SSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVE 125
           S E  L+  ES      R  +    + C  S SSS     SD+ SS+ ++E  + +    
Sbjct: 76  SREKLLSGNESSSKKRERKKKRKKKS-CRSSSSSSS----SDSSSSSSDSEDEEKKQ--- 127

Query: 126 GDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRL 185
                      G++ ++ ++ S  S+ ++    +S  K++ +  K     ++K K+ +R 
Sbjct: 128 -----------GKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKD-VRS 175

Query: 186 LRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEE 225
           L +KR+ +      L  +SS S+SD   D         EE
Sbjct: 176 LSKKRKKSYPDDKPLSSESS-SESDYEEDVQAKKKRRCEE 214



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 15/94 (15%)

Query: 144 RSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLR------QKREAAARKK 197
           + + E     +K   +  +K N      +  + +  K R +LL       +KRE   ++K
Sbjct: 45  KKQLENKKTGSKALAEFEEKMN------ENWKKELEKSREKLLSGNESSSKKRERKKKRK 98

Query: 198 YNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSK 231
               + SS+S S    DSS+SSSD ++E     K
Sbjct: 99  KKSCRSSSSSSSS---DSSSSSSDSEDEEKKQGK 129


>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
           [Homo sapiens]
          Length = 666

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 58/255 (22%), Positives = 88/255 (34%), Gaps = 33/255 (12%)

Query: 10  VEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSES 69
           +E+L  S+A  +A  +++    D   + E+       + S               D  E 
Sbjct: 4   MEDLFGSDADSEAERKDSDSGSDSDSDQENAASGSNASGS-------------ESDQDER 50

Query: 70  QLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPS 129
             +   S+K   G   E + ++H      S  H   SD  S A E    +     + DPS
Sbjct: 51  GDSGQPSNKELFGDDSEDEGASH---HSGSDNHSERSDNRSEASERSDHE-----DNDPS 102

Query: 130 GV---SGATVGR----KSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKER 182
            V   SG+        +  RS   S  S     +   S D++ GR  K      Q   E+
Sbjct: 103 DVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDK----SDQSDDEK 158

Query: 183 IRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDGPP 242
           I+      E A     + LQ+S   +     D        D+E    S+   A   D  P
Sbjct: 159 IQN-SDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDERP 217

Query: 243 VVAHYDMSDTNSDPE 257
           V +  D    NSD E
Sbjct: 218 VASDNDDEKQNSDDE 232


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 44/185 (23%), Positives = 73/185 (39%), Gaps = 32/185 (17%)

Query: 37   LESQVQKDGVADSTVISSMPCLLMELR-------------RDSSESQLASTESDKPTTGR 83
            L S V +D  A S V+SSMP    E               +D+ E    +   DK    +
Sbjct: 1757 LASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEK 1816

Query: 84   VYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRS 143
              +S   +    S SS  H +   T  S        +++                KS RS
Sbjct: 1817 KRDSSLRSRSKRSKSSE-HKSRKRTSESRSRARKRSSKS----------------KSHRS 1859

Query: 144  RSESETSTMAAKKNRQSSDKQNGR--VAKVKGHRSQKHKERIRLLRQKREAAARKKYNLL 201
            ++ S + +   +++ +S  K  GR  V+K K  RS KH+ + R  ++KR ++   +  + 
Sbjct: 1860 QTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVR 1919

Query: 202  QDSST 206
              S T
Sbjct: 1920 ARSRT 1924



 Score = 29.3 bits (64), Expect = 6.6
 Identities = 55/258 (21%), Positives = 100/258 (38%), Gaps = 23/258 (8%)

Query: 9   KVEELIESEAPPKASEQETAKEEDGSVELES-QVQKDGVADSTVISSMPCLLMELRRDSS 67
           K E+  + +  P+ SE +T   +DG+++LES    K     S V   +P         S 
Sbjct: 122 KKEKEKKYKRQPEESESKTKSHDDGNIDLESDSFLKFDSEPSAVALELPTRAF---GPSE 178

Query: 68  ESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGD 127
            ++  +   + P    V    S  H + +   +   A+   +S++  +E S+   AV  +
Sbjct: 179 TNESPAVVLEPPV---VSMEVSEPHILETLKPATKTAELSVVSTSVISEQSEQSVAVMPE 235

Query: 128 PS------GVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKE 181
           PS        + A V   +   +S     TM+ +   +S          +K   S   + 
Sbjct: 236 PSMTKILDSFAAAPVPTTTLVLKSSEPVVTMSVEYQMKS---------VLKSVESTSPEP 286

Query: 182 RIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIP-DG 240
              +L +   A   +    L  SS + +++  + STS++ D  E S        E P D 
Sbjct: 287 SKIMLVEPPVAKVLEPSETLVVSSETPTEVYPEPSTSTTMDFPESSAIEALRLPEQPVDV 346

Query: 241 PPVVAHYDMSDTNSDPEV 258
           P  +A   M+     PE+
Sbjct: 347 PSEIADSSMTRPQELPEL 364


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 44/185 (23%), Positives = 73/185 (39%), Gaps = 32/185 (17%)

Query: 37   LESQVQKDGVADSTVISSMPCLLMELR-------------RDSSESQLASTESDKPTTGR 83
            L S V +D  A S V+SSMP    E               +D+ E    +   DK    +
Sbjct: 1757 LASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEK 1816

Query: 84   VYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRRS 143
              +S   +    S SS  H +   T  S        +++                KS RS
Sbjct: 1817 KRDSSLRSRSKRSKSSE-HKSRKRTSESRSRARKRSSKS----------------KSHRS 1859

Query: 144  RSESETSTMAAKKNRQSSDKQNGR--VAKVKGHRSQKHKERIRLLRQKREAAARKKYNLL 201
            ++ S + +   +++ +S  K  GR  V+K K  RS KH+ + R  ++KR ++   +  + 
Sbjct: 1860 QTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVR 1919

Query: 202  QDSST 206
              S T
Sbjct: 1920 ARSRT 1924



 Score = 29.3 bits (64), Expect = 6.6
 Identities = 55/258 (21%), Positives = 100/258 (38%), Gaps = 23/258 (8%)

Query: 9   KVEELIESEAPPKASEQETAKEEDGSVELES-QVQKDGVADSTVISSMPCLLMELRRDSS 67
           K E+  + +  P+ SE +T   +DG+++LES    K     S V   +P         S 
Sbjct: 122 KKEKEKKYKRQPEESESKTKSHDDGNIDLESDSFLKFDSEPSAVALELPTRAF---GPSE 178

Query: 68  ESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGD 127
            ++  +   + P    V    S  H + +   +   A+   +S++  +E S+   AV  +
Sbjct: 179 TNESPAVVLEPPV---VSMEVSEPHILETLKPATKTAELSVVSTSVISEQSEQSVAVMPE 235

Query: 128 PS------GVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKE 181
           PS        + A V   +   +S     TM+ +   +S          +K   S   + 
Sbjct: 236 PSMTKILDSFAAAPVPTTTLVLKSSEPVVTMSVEYQMKS---------VLKSVESTSPEP 286

Query: 182 RIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIP-DG 240
              +L +   A   +    L  SS + +++  + STS++ D  E S        E P D 
Sbjct: 287 SKIMLVEPPVAKVLEPSETLVVSSETPTEVYPEPSTSTTMDFPESSAIEALRLPEQPVDV 346

Query: 241 PPVVAHYDMSDTNSDPEV 258
           P  +A   M+     PE+
Sbjct: 347 PSEIADSSMTRPQELPEL 364


>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
          Length = 888

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 64/293 (21%), Positives = 104/293 (35%), Gaps = 46/293 (15%)

Query: 1   MKMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLM 60
           +KME    K EE    E P K  E+E  KE++   E E + +K    +   +S       
Sbjct: 97  IKME----KKEEEENGERPRKKKEKEKEKEKEKEKEKEREKEK----EKATVSENVAASA 148

Query: 61  ELRRDSSESQLASTESDKPTTGRVYESDSS---------NHCMLSPSSSGHLADSDTLSS 111
                ++     +T    PTT    E   S         N  +L   S   L D D   S
Sbjct: 149 AATTPATSPPAVNTSPSVPTTTTATEEQVSEPKKWNLRRNRPLLDFVSMEELNDMDDYDS 208

Query: 112 AEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKV 171
            ++N+        +G     +    G        E E S     +N + +D+ +   A  
Sbjct: 209 EDDNDWRPTVVKRKGRS---ASQKEGSDGDNEDDEDEGSGSDEDENDEGNDEDHSSPASE 265

Query: 172 KGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDS---STSSSDDDEEVSG 228
            G                     +KK  +L  +S  D +LT DS   S S S++D  +  
Sbjct: 266 GG-------------------CKKKKSKVLSRNSADDEELTNDSLTLSQSKSNEDSLILE 306

Query: 229 SSKTITAEIPDGPPVVAHYDMSDTNSD-PEVVNVDNLLAAAVVQEHSNSVGGQ 280
            S+  +++  D   ++    + D + D  E++  DN      V E    V G+
Sbjct: 307 KSQNWSSQKMD-HILICCVCLGDNSEDADEIIQCDN--CGITVHEGCYGVDGE 356


>gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]
          Length = 948

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 64/293 (21%), Positives = 104/293 (35%), Gaps = 46/293 (15%)

Query: 1   MKMEEAVGKVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLM 60
           +KME    K EE    E P K  E+E  KE++   E E + +K    +   +S       
Sbjct: 97  IKME----KKEEEENGERPRKKKEKEKEKEKEKEKEKEREKEK----EKATVSENVAASA 148

Query: 61  ELRRDSSESQLASTESDKPTTGRVYESDSS---------NHCMLSPSSSGHLADSDTLSS 111
                ++     +T    PTT    E   S         N  +L   S   L D D   S
Sbjct: 149 AATTPATSPPAVNTSPSVPTTTTATEEQVSEPKKWNLRRNRPLLDFVSMEELNDMDDYDS 208

Query: 112 AEENEPSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKV 171
            ++N+        +G     +    G        E E S     +N + +D+ +   A  
Sbjct: 209 EDDNDWRPTVVKRKGRS---ASQKEGSDGDNEDDEDEGSGSDEDENDEGNDEDHSSPASE 265

Query: 172 KGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDS---STSSSDDDEEVSG 228
            G                     +KK  +L  +S  D +LT DS   S S S++D  +  
Sbjct: 266 GG-------------------CKKKKSKVLSRNSADDEELTNDSLTLSQSKSNEDSLILE 306

Query: 229 SSKTITAEIPDGPPVVAHYDMSDTNSD-PEVVNVDNLLAAAVVQEHSNSVGGQ 280
            S+  +++  D   ++    + D + D  E++  DN      V E    V G+
Sbjct: 307 KSQNWSSQKMD-HILICCVCLGDNSEDADEIIQCDN--CGITVHEGCYGVDGE 356


>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
          Length = 237

 Score = 38.5 bits (88), Expect = 0.011
 Identities = 39/138 (28%), Positives = 65/138 (47%), Gaps = 17/138 (12%)

Query: 65  DSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAV 124
           DSS S   S + DK    R  +  + +H   S  SS    +SD+  S ++ + S+  T  
Sbjct: 103 DSSSSSSDSEDEDKKQGKRRKKKKNRSH--KSSESSMSETESDSKDSLKKKKKSKDGTEK 160

Query: 125 EGDPSGVSGATVGRK--------SRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRS 176
           E D   + G +  RK        S  S SESE       K ++SS+++     K K  + 
Sbjct: 161 EKD---IKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTK--KK 215

Query: 177 QKHKERIRLLRQKREAAA 194
           +KHK+  +  ++K++AA+
Sbjct: 216 KKHKKHSK--KKKKKAAS 231



 Score = 28.9 bits (63), Expect = 8.7
 Identities = 29/117 (24%), Positives = 51/117 (43%), Gaps = 19/117 (16%)

Query: 128 PSGVSGATVGRKSRRSRSESETSTMAAKKNRQSS-------DKQNGRVAKVKGHRSQKHK 180
           P   SG T+     R R   E      +K ++ S       +K N    K      +KH+
Sbjct: 12  PIQSSGPTIQDYLNRPRPTWEEVKEQLEKKKKGSKALAEFEEKMNENWKK----ELEKHR 67

Query: 181 ERI------RLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSK 231
           E++         +++R+   +KK      SS+S SD +  SS+S S+D+++  G  +
Sbjct: 68  EKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSS--SSSSDSEDEDKKQGKRR 122


>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
          Length = 247

 Score = 38.5 bits (88), Expect = 0.011
 Identities = 39/138 (28%), Positives = 65/138 (47%), Gaps = 17/138 (12%)

Query: 65  DSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAV 124
           DSS S   S + DK    R  +  + +H   S  SS    +SD+  S ++ + S+  T  
Sbjct: 113 DSSSSSSDSEDEDKKQGKRRKKKKNRSH--KSSESSMSETESDSKDSLKKKKKSKDGTEK 170

Query: 125 EGDPSGVSGATVGRK--------SRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRS 176
           E D   + G +  RK        S  S SESE       K ++SS+++     K K  + 
Sbjct: 171 EKD---IKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTK--KK 225

Query: 177 QKHKERIRLLRQKREAAA 194
           +KHK+  +  ++K++AA+
Sbjct: 226 KKHKKHSK--KKKKKAAS 241



 Score = 28.9 bits (63), Expect = 8.7
 Identities = 29/117 (24%), Positives = 51/117 (43%), Gaps = 19/117 (16%)

Query: 128 PSGVSGATVGRKSRRSRSESETSTMAAKKNRQSS-------DKQNGRVAKVKGHRSQKHK 180
           P   SG T+     R R   E      +K ++ S       +K N    K      +KH+
Sbjct: 22  PIQSSGPTIQDYLNRPRPTWEEVKEQLEKKKKGSKALAEFEEKMNENWKK----ELEKHR 77

Query: 181 ERI------RLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSK 231
           E++         +++R+   +KK      SS+S SD +  SS+S S+D+++  G  +
Sbjct: 78  EKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSS--SSSSDSEDEDKKQGKRR 132


>gi|21361684 G patch domain containing 1 [Homo sapiens]
          Length = 931

 Score = 38.5 bits (88), Expect = 0.011
 Identities = 58/238 (24%), Positives = 100/238 (42%), Gaps = 34/238 (14%)

Query: 2   KMEEAVGKVEELIESEA-PPKASEQETA-KEEDGSVELESQ--VQKDGVADSTVISSMPC 57
           K E+++ +   L  S+A PPK        KEE+ + EL +   V KD  A +    S P 
Sbjct: 691 KKEDSISEFLSLARSKAEPPKQQSSPLVNKEEEHAPELSANQTVNKDVDAQAEGEGSRPS 750

Query: 58  LLM---------ELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDT 108
           + +         + +  SSE +   +E D+  +G      S +  +   SS  H      
Sbjct: 751 MDLFRAIFASSSDEKSSSSEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAHAL---- 806

Query: 109 LSSAEENEPS---QAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQN 165
           + + +E  PS   Q     E +  G     V   + R   E        +K++++ DK  
Sbjct: 807 VPAPQEPPPSFPIQKMQIDEREEFGPRLPPVFCPNARQTLEVPQK----EKHKKNKDKHK 862

Query: 166 GRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDD 223
            +    K HR +K K++     +K +   ++K    + SS+S+S    DSS S SD++
Sbjct: 863 AK----KEHRRKKEKKK---KHRKHKHKGKQKNKKPEKSSSSESS---DSSDSQSDEE 910



 Score = 28.9 bits (63), Expect = 8.7
 Identities = 28/122 (22%), Positives = 53/122 (43%), Gaps = 3/122 (2%)

Query: 117 PSQAETAVEGDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQ-NGRVAKVKGHR 175
           P  A T+       V   + G+ +    + S+    A+K+     +    G    V    
Sbjct: 379 PMVAATSENSHLLQVLSESAGKATPDPGTHSKHQLNASKRAELLGETPIQGSATSVLEFL 438

Query: 176 SQKHKERIRLLRQKRE--AAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTI 233
           SQK KERI+ ++Q  +  AA  K  +L Q++ +S + L+  ++      +  + G + T+
Sbjct: 439 SQKDKERIKEMKQATDLKAAQLKARSLAQNAQSSRAQLSPAAAAGHCSWNMALGGGTATL 498

Query: 234 TA 235
            A
Sbjct: 499 KA 500


>gi|157738619 smoothelin-like 1 [Homo sapiens]
          Length = 512

 Score = 38.5 bits (88), Expect = 0.011
 Identities = 60/280 (21%), Positives = 110/280 (39%), Gaps = 39/280 (13%)

Query: 4   EEAVGKVEELIESEAPPKASEQETAKEEDG-------------SVELESQVQKDGVADST 50
           EE  G   + I    P ++ +QE A  EDG              V++ESQ +  G  D+ 
Sbjct: 50  EETKGTAGKAINEGPPTESGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKEDAE 109

Query: 51  VISSMPCLLMELRRDSSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLS 110
                     EL+++  E +  +T   +  TGR  E+ S         S+  LA     +
Sbjct: 110 A---------ELKKEDGEKE-ETTVGSQEMTGRKEETKSEPKEAEEKEST--LASEKQKA 157

Query: 111 SAEENEPSQAETAVEGD-PSGVSGATVGRKSRRSRSESET------STMAAKKNRQSSDK 163
             +E +P   + A   D       ATV  +  ++ S+ ET      ST   +K      K
Sbjct: 158 EEKEAKPESGQKADANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAK 217

Query: 164 QNGRVAKVKGHRSQKHKERIRLLRQKREAAARKKYNLLQDS-STSDSDLTCDSSTSSSDD 222
              + A V+     + KE     +++ +  A+++ +  +++    +++    S     D 
Sbjct: 218 AESQKAVVEDEAKAEPKEPDG--KEEAKHGAKEEADAKEEAEDAEEAEPGSPSEEQEQDV 275

Query: 223 DEEVSGSSKTITA---EIPDGPPVVAHYDMSDTNSDPEVV 259
           ++E  G +  I +   E P+ P    H ++S     P+ V
Sbjct: 276 EKEPEGGAGVIPSSPEEWPESPTGEGH-NLSTDGLGPDCV 314


>gi|109809739 La ribonucleoprotein domain family, member 7 [Homo
           sapiens]
          Length = 582

 Score = 37.7 bits (86), Expect = 0.019
 Identities = 40/208 (19%), Positives = 87/208 (41%), Gaps = 20/208 (9%)

Query: 24  EQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSE-SQLASTESDKPTTG 82
           E++  K++ G ++ E  +Q     ++   S+     M+  R +SE S + STE  K  + 
Sbjct: 217 EKKKKKKKKGRMKKEDNIQAK--EENMDTSNTSISKMKRSRPTSEGSDIESTEPQKQCSK 274

Query: 83  RVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRR 142
           +  + D      L    +G    S +  +      S+ +  ++ D        + +++  
Sbjct: 275 KKKKRDRVEASSLPEVRTGKRKRSSSEDAESLAPRSKVKKIIQKD--------IIKEASE 326

Query: 143 SRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKER---------IRLLRQKREAA 193
           +  E+    ++ ++ + + D ++  + K K    +KHKER         +R+L +     
Sbjct: 327 ASKENRDIEISTEEEKDTGDLKDSSLLKTKRKHKKKHKERHKMGEEVIPLRVLSKSEWMD 386

Query: 194 ARKKYNLLQDSSTSDSDLTCDSSTSSSD 221
            +K+Y  LQ +S +    T     S S+
Sbjct: 387 LKKEYLALQKASMASLKKTISQIKSESE 414



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 22/94 (23%), Positives = 44/94 (46%), Gaps = 3/94 (3%)

Query: 138 RKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKK 197
           +K ++ R + E +  A ++N  +S   N  ++K+K  R       I     +++ + +KK
Sbjct: 221 KKKKKGRMKKEDNIQAKEENMDTS---NTSISKMKRSRPTSEGSDIESTEPQKQCSKKKK 277

Query: 198 YNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSK 231
                ++S+     T     SSS+D E ++  SK
Sbjct: 278 KRDRVEASSLPEVRTGKRKRSSSEDAESLAPRSK 311


>gi|109809741 La ribonucleoprotein domain family, member 7 [Homo
           sapiens]
          Length = 582

 Score = 37.7 bits (86), Expect = 0.019
 Identities = 40/208 (19%), Positives = 87/208 (41%), Gaps = 20/208 (9%)

Query: 24  EQETAKEEDGSVELESQVQKDGVADSTVISSMPCLLMELRRDSSE-SQLASTESDKPTTG 82
           E++  K++ G ++ E  +Q     ++   S+     M+  R +SE S + STE  K  + 
Sbjct: 217 EKKKKKKKKGRMKKEDNIQAK--EENMDTSNTSISKMKRSRPTSEGSDIESTEPQKQCSK 274

Query: 83  RVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVEGDPSGVSGATVGRKSRR 142
           +  + D      L    +G    S +  +      S+ +  ++ D        + +++  
Sbjct: 275 KKKKRDRVEASSLPEVRTGKRKRSSSEDAESLAPRSKVKKIIQKD--------IIKEASE 326

Query: 143 SRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKER---------IRLLRQKREAA 193
           +  E+    ++ ++ + + D ++  + K K    +KHKER         +R+L +     
Sbjct: 327 ASKENRDIEISTEEEKDTGDLKDSSLLKTKRKHKKKHKERHKMGEEVIPLRVLSKSEWMD 386

Query: 194 ARKKYNLLQDSSTSDSDLTCDSSTSSSD 221
            +K+Y  LQ +S +    T     S S+
Sbjct: 387 LKKEYLALQKASMASLKKTISQIKSESE 414



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 22/94 (23%), Positives = 44/94 (46%), Gaps = 3/94 (3%)

Query: 138 RKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRLLRQKREAAARKK 197
           +K ++ R + E +  A ++N  +S   N  ++K+K  R       I     +++ + +KK
Sbjct: 221 KKKKKGRMKKEDNIQAKEENMDTS---NTSISKMKRSRPTSEGSDIESTEPQKQCSKKKK 277

Query: 198 YNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSK 231
                ++S+     T     SSS+D E ++  SK
Sbjct: 278 KRDRVEASSLPEVRTGKRKRSSSEDAESLAPRSK 311


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 37.7 bits (86), Expect = 0.019
 Identities = 70/336 (20%), Positives = 123/336 (36%), Gaps = 35/336 (10%)

Query: 66  SSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVE 125
           S+ S  AST ++  ++    E+ ++ +   S +SSG    S   +S      S+A TA  
Sbjct: 141 STTSSGASTATNSDSSTTSSEASTATNSESSTTSSG---ASTATNSESSTVSSRASTATN 197

Query: 126 GDPSGVSGATVGRKSRRSRSESETSTMAA--KKNRQSSDKQNGRVAKVKGHRSQKHKERI 183
            + S  S       S  + SES T++  A    N +SS   +G         S       
Sbjct: 198 SESSTTSSGA----STATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAG 253

Query: 184 RLLRQKREAAARKKYNLL-QDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDGPP 242
                +    +         +SST  S ++  +++ SS      + ++ + ++    G  
Sbjct: 254 TATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGAN 313

Query: 243 VVAHYDMSDTNS------DPEVVNVDNLLAAAVVQEHSNSVGGQDT----GATWRTSGLL 292
              + D S T+S      + E     +  + A   E S +  G  T    G++  +SG  
Sbjct: 314 TATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTS 373

Query: 293 EELNAEAGHLDPGFL------ASDKTSAGNAPLNEEINIASSDSEV----EIVGVQEHAR 342
              N+E+  +  G        +S  +S  +   N E +  SS +      E       A 
Sbjct: 374 TATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGAN 433

Query: 343 CVHPRGGVIQSVSSWKHGSGTQYVSTRQTQSWTAVT 378
                G  + S      GSGT  ++   T S +A T
Sbjct: 434 TATNSGSSVTSA-----GSGTAALTGMHTTSHSAST 464



 Score = 37.0 bits (84), Expect = 0.032
 Identities = 53/263 (20%), Positives = 101/263 (38%), Gaps = 15/263 (5%)

Query: 66  SSESQLASTESDKPTTGRVYESDSSNHCMLSPSSSGHLADSDTLSSAEENEPSQAETAVE 125
           S  S   ++ES  P++G    ++S +    S +S+   +DS T SS    E S A  +  
Sbjct: 115 SGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSS----EASTATNSES 170

Query: 126 GDPSGVSGATVGRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQKHKERIRL 185
              S  SGA+    S  S   S  ST  A  +  S+       A     R+  +      
Sbjct: 171 STTS--SGASTATNSESSTVSSRAST--ATNSESSTTSSGASTATNSESRTTSNGAGTAT 226

Query: 186 LRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDGPPVVA 245
             +    ++        +SST  S     +++ SS        ++ + ++ +  G   V 
Sbjct: 227 NSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVT 286

Query: 246 HYDMSDTNSDPEVVNVDNLLAAAVVQEHSNSVGGQDTGATWRTSGLLEELNAEAGHLDPG 305
           + + S  +S     N      ++     +N+    D+  T  +SG     N+E+     G
Sbjct: 287 NSESSTPSSG---ANTATNSESSTTSSGANTATNSDSSTT--SSGASTATNSESSTTSSG 341

Query: 306 FLASDKTSAGNAPLNEEINIASS 328
             AS  T++ ++  +   + A++
Sbjct: 342 --ASTATNSESSTTSSGASTATN 362


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.302    0.119    0.320 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,325,322
Number of Sequences: 37866
Number of extensions: 678306
Number of successful extensions: 4394
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 278
Number of HSP's that attempted gapping in prelim test: 3165
Number of HSP's gapped (non-prelim): 983
length of query: 404
length of database: 18,247,518
effective HSP length: 105
effective length of query: 299
effective length of database: 14,271,588
effective search space: 4267204812
effective search space used: 4267204812
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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