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Search of human proteins with 21450759
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21450759 adenylate kinase domain containing 1 isoform 2
[Homo sapiens]
(421 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21450759 adenylate kinase domain containing 1 isoform 2 [Homo... 853 0.0
gi|237858799 adenylate kinase domain containing 1 isoform 1 [Hom... 849 0.0
gi|4502013 adenylate kinase 2 isoform a [Homo sapiens] 62 1e-09
gi|7524346 adenylate kinase 2 isoform b [Homo sapiens] 62 1e-09
gi|53832001 adenylate kinase 3-like 1 isoform 7 [Homo sapiens] 58 2e-08
gi|53832003 adenylate kinase 3-like 1 isoform 5 [Homo sapiens] 58 2e-08
gi|8051579 adenylate kinase 3-like 1 isoform 6 [Homo sapiens] 58 2e-08
gi|19923437 adenylate kinase 3 [Homo sapiens] 55 9e-08
gi|22749187 putative adenylate kinase-like protein C9orf98 [Homo... 55 1e-07
gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens] 42 8e-04
gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens] 42 8e-04
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H... 42 0.001
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 41 0.002
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 41 0.002
gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens] 41 0.002
gi|24308223 hypothetical protein LOC57577 [Homo sapiens] 40 0.004
gi|118600967 shroom family member 4 [Homo sapiens] 40 0.005
gi|148727333 adenylate kinase 7 [Homo sapiens] 39 0.007
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 39 0.009
gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens] 39 0.009
gi|17975763 myelin transcription factor 1 [Homo sapiens] 39 0.012
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 38 0.015
gi|22749303 hypothetical protein LOC196477 [Homo sapiens] 38 0.015
gi|74315997 l-myc-1 proto-oncogene isoform 1 [Homo sapiens] 38 0.020
gi|74315995 l-myc-1 proto-oncogene isoform 1 [Homo sapiens] 38 0.020
gi|21735415 centromere protein B [Homo sapiens] 38 0.020
gi|122937434 Rho-guanine nucleotide exchange factor [Homo sapiens] 38 0.020
gi|20806097 nucleolar complex associated 3 homolog [Homo sapiens] 38 0.020
gi|221219020 NYD-SP11 protein [Homo sapiens] 37 0.026
gi|4504425 high-mobility group box 1 [Homo sapiens] 37 0.026
>gi|21450759 adenylate kinase domain containing 1 isoform 2 [Homo
sapiens]
Length = 421
Score = 853 bits (2204), Expect = 0.0
Identities = 421/421 (100%), Positives = 421/421 (100%)
Query: 1 MTSQEKTEEYPFADIFDEDETERNFLLSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVE 60
MTSQEKTEEYPFADIFDEDETERNFLLSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVE
Sbjct: 1 MTSQEKTEEYPFADIFDEDETERNFLLSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVE 60
Query: 61 ALPILEEQIAAETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSL 120
ALPILEEQIAAETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSL
Sbjct: 61 ALPILEEQIAAETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSL 120
Query: 121 SQDAMTTLQQIELIKNLNLKPDVIINIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEV 180
SQDAMTTLQQIELIKNLNLKPDVIINIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEV
Sbjct: 121 SQDAMTTLQQIELIKNLNLKPDVIINIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEV 180
Query: 181 IENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENI 240
IENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENI
Sbjct: 181 IENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENI 240
Query: 241 VKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKRAAILTKLQG 300
VKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKRAAILTKLQG
Sbjct: 241 VKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKRAAILTKLQG 300
Query: 301 AEEEINDTMENDELFRTLASYKLIAPRYRWQRSKWGRTCPVNLKDGNIYSGLPDYSVSFL 360
AEEEINDTMENDELFRTLASYKLIAPRYRWQRSKWGRTCPVNLKDGNIYSGLPDYSVSFL
Sbjct: 301 AEEEINDTMENDELFRTLASYKLIAPRYRWQRSKWGRTCPVNLKDGNIYSGLPDYSVSFL 360
Query: 361 GKIYCLSSEEALKPFLLNPRPYLLPPMPGPPCKVFILGPQYSGKTTLCNMLAENYKGKVT 420
GKIYCLSSEEALKPFLLNPRPYLLPPMPGPPCKVFILGPQYSGKTTLCNMLAENYKGKVT
Sbjct: 361 GKIYCLSSEEALKPFLLNPRPYLLPPMPGPPCKVFILGPQYSGKTTLCNMLAENYKGKVT 420
Query: 421 N 421
N
Sbjct: 421 N 421
>gi|237858799 adenylate kinase domain containing 1 isoform 1 [Homo
sapiens]
Length = 1911
Score = 849 bits (2194), Expect = 0.0
Identities = 419/421 (99%), Positives = 420/421 (99%)
Query: 1 MTSQEKTEEYPFADIFDEDETERNFLLSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVE 60
MTSQEKTEEYPFADIFDEDETERNFLLSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVE
Sbjct: 1 MTSQEKTEEYPFADIFDEDETERNFLLSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVE 60
Query: 61 ALPILEEQIAAETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSL 120
ALPILEEQIAAETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSL
Sbjct: 61 ALPILEEQIAAETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSL 120
Query: 121 SQDAMTTLQQIELIKNLNLKPDVIINIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEV 180
SQDAMTTLQQIELIKNLNLKPDVIINIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEV
Sbjct: 121 SQDAMTTLQQIELIKNLNLKPDVIINIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEV 180
Query: 181 IENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENI 240
IENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENI
Sbjct: 181 IENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENI 240
Query: 241 VKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKRAAILTKLQG 300
VKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKRAAILTKLQG
Sbjct: 241 VKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKRAAILTKLQG 300
Query: 301 AEEEINDTMENDELFRTLASYKLIAPRYRWQRSKWGRTCPVNLKDGNIYSGLPDYSVSFL 360
AEEEINDTMENDELFRTLASYKLIAPRYRWQRSKWGRTCPVNLKDGNIYSGLPDYSVSFL
Sbjct: 301 AEEEINDTMENDELFRTLASYKLIAPRYRWQRSKWGRTCPVNLKDGNIYSGLPDYSVSFL 360
Query: 361 GKIYCLSSEEALKPFLLNPRPYLLPPMPGPPCKVFILGPQYSGKTTLCNMLAENYKGKVT 420
GKIYCLSSEEALKPFLLNPRPYLLPPMPGPPCKVFILGPQYSGKTTLCNMLAENYKGKV
Sbjct: 361 GKIYCLSSEEALKPFLLNPRPYLLPPMPGPPCKVFILGPQYSGKTTLCNMLAENYKGKVV 420
Query: 421 N 421
+
Sbjct: 421 D 421
Score = 67.8 bits (164), Expect = 2e-11
Identities = 98/404 (24%), Positives = 168/404 (41%), Gaps = 65/404 (16%)
Query: 30 PVCFVVFGKPGVGKTTLARYITQAWKCIRVEALPILEEQI--AAETESGVMLQSMLISGQ 87
P+ ++ G P GKTT+A+ IT + + L + ETE +ML L G
Sbjct: 1411 PIRIIIVGPPKSGKTTVAKKITSEYGLKHLSIGGALRYVLNNHPETELALMLNWHLHKGM 1470
Query: 88 SIPDELVIKLMLEKLNSPEVCH-FGYIITEIPSLSQDAMTTLQQIELIKNLNLKPDVIIN 146
+ PDEL I+ LE VC+ G +I P T Q+ L++ ++ P VI
Sbjct: 1471 TAPDELAIQ-ALELSLMESVCNTAGVVIDGYP-------VTKHQMNLLEARSIIPMVIFE 1522
Query: 147 IKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQ 206
+ P ++ +R+ +++ N Y V N+ K +K GE + +EQ
Sbjct: 1523 LSVPSKEIFKRLLLEKE-NEQRLPYPLHNSAQIVAVNNVKYRKNI-----GEIRQYYQEQ 1576
Query: 207 EEE----EAFIAEMQMVAEILHHLVQRPEDYLENVENIVKLYKETILQTLEEVMAEHNPQ 262
+ + F ++ + E++ + VQ Y++ +K K + L PQ
Sbjct: 1577 HQNWYVIDGFHSKWWVWNEVIKN-VQMVNKYMQTYLERIKAGKAACIDKL-----CITPQ 1630
Query: 263 YLIELNGN---------KPAEELF-MIVMDRLKYLNLKRAAILTKLQGAEEEINDTMEND 312
L+ G ++ELF D L++ R ++E++N +EN
Sbjct: 1631 ELLSRLGEFEQFCPVSLAESQELFDCSATDSLEFAAEFRGHYYK--MSSQEKLNKFLENP 1688
Query: 313 ELF------RTLASYKLIAPRYRWQ--RSKWGRT------CPVNLKDGN-----IYSGLP 353
EL+ L S +I R +S++ + CPV KDGN + G
Sbjct: 1689 ELYVPPLAPHPLPSADMIPKRLTLSELKSRFPKCAELQGYCPVTYKDGNQRYEALVPGSI 1748
Query: 354 DYSVSFLGKIYCLSSEEALKPFLLNP-------RPYLLPPMPGP 390
+Y++ + +IY ++E L+ FL +P P+ LPP+ P
Sbjct: 1749 NYALEYHNRIYICENKEKLQKFLRSPLKYWEQKLPHKLPPLREP 1792
Score = 64.3 bits (155), Expect = 2e-10
Identities = 84/381 (22%), Positives = 149/381 (39%), Gaps = 65/381 (17%)
Query: 73 TESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSLSQDAMTTLQQIE 132
TE +++S L+ + +P E++ ++ E + G+I+ P ++A +
Sbjct: 1082 TEEEEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEA-------Q 1134
Query: 133 LIKNLNLKPDVIINIKCPDYDLCQR----------------------ISGQRQHNNTGYI 170
+ + PD + I+ D D+ R I + I
Sbjct: 1135 FLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTI 1194
Query: 171 YSRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRP 230
R ++E +K+++ +D + EEE EE ++ I E + + +
Sbjct: 1195 AKRRA--ELILERDKKRRENVVRDDEEISEEELEEDNDDIENILEDEFPKD--EEEMSGE 1250
Query: 231 EDYLENVENIVKLYKETILQTLE------EVMAEHNPQYLI---ELNGNKPAEELFMIVM 281
ED + + I +L E + + E +++ + +YLI +NG + + +
Sbjct: 1251 EDEEQETDAIERLRGE-LGEKFEADTHNLQIIQDELERYLIPIISINGARRNHIVQYTLN 1309
Query: 282 DRLKYLNLKRAAILTKLQGAEEEINDTMENDELFRTLASYKLIAPRYRWQRSKWGRTCPV 341
+LK L RA+I K + M +YK I S +G PV
Sbjct: 1310 MKLKPLVENRASIFEKCHPIPAPLAQKM-------LTFTYKYI--------SSFGYWDPV 1354
Query: 342 NLKDGNIYSGL-----PDYSVSFLGKIYCLSSEEALKPFLLNPRPYLLPPMPGP--PCKV 394
L +G + P Y V IY LSS+E + F+ NP Y+ P P P P ++
Sbjct: 1355 KLSEGETIKPVENAENPIYPVIHRQYIYFLSSKETKEKFMKNPIKYIRQPKPKPTVPIRI 1414
Query: 395 FILGPQYSGKTTLCNMLAENY 415
I+GP SGKTT+ + Y
Sbjct: 1415 IIVGPPKSGKTTVAKKITSEY 1435
Score = 56.2 bits (134), Expect = 5e-08
Identities = 65/245 (26%), Positives = 107/245 (43%), Gaps = 17/245 (6%)
Query: 177 DPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLEN 236
+PE + ++ + KG +E E E+ E + E E + V E + E
Sbjct: 778 EPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFP---EDSYPDVPEMEPFKEK 834
Query: 237 VENIVKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKRAAILT 296
+ + + L+K+ LE ++E + L ++ +EL V++ ++ A LT
Sbjct: 835 IGSFIILWKQ-----LEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELT 889
Query: 297 KLQGAEEEINDTMENDELFRTLASYKLIAPRYRWQRSK--WGRT---CPVNLKDGNIYS- 350
+ EEE D E+ L + + + K G T CPV LK+ I
Sbjct: 890 G-EDYEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQP 948
Query: 351 GLPDYSVSFLGKIYCLSSEEALKPFLLNPRPYLL--PPMPGPPCKVFILGPQYSGKTTLC 408
G + + + KIY SS EA + FL +P Y+ P+ PP ++ ++GPQ SGKT
Sbjct: 949 GNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCG 1008
Query: 409 NMLAE 413
LAE
Sbjct: 1009 RQLAE 1013
Score = 28.9 bits (63), Expect = 9.2
Identities = 22/98 (22%), Positives = 43/98 (43%), Gaps = 13/98 (13%)
Query: 166 NTGYIYSRDQWDPEVIEN---HRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEI 222
N Y+ + + D +++E +KKK+ +++ + EEE +EE + M++ A+
Sbjct: 672 NRIYLQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKE 731
Query: 223 LHHLVQRPEDYLENVENIVKLYKETILQTLEEVMAEHN 260
E+ +E E L+ EE A H+
Sbjct: 732 AEETDNEDEEEIEGDE----------LEVHEEPEASHD 759
>gi|4502013 adenylate kinase 2 isoform a [Homo sapiens]
Length = 239
Score = 61.6 bits (148), Expect = 1e-09
Identities = 49/193 (25%), Positives = 92/193 (47%), Gaps = 22/193 (11%)
Query: 29 KPVCFVVFGKPGVGKTTLARYITQAWKCIRVEALPILEEQIAAETESGVMLQSMLISGQS 88
K + V+ G PG GK T A + + + + +L +A+ +E G L++ + +G+
Sbjct: 14 KGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKL 73
Query: 89 IPDELVIKLMLEKLNSPEVCHFGYIITEIPSLSQDAMTTLQQIELIKNL----NLKPDVI 144
+ DE+V++L+ + L +P +C G+++ P T++Q E++ +L K D +
Sbjct: 74 VSDEMVVELIEKNLETP-LCKNGFLLDGFP-------RTVRQAEMLDDLMEKRKEKLDSV 125
Query: 145 INIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEE 204
I PD L +RI+G+ H +G Y ++++P KE KD E
Sbjct: 126 IEFSIPDSLLIRRITGRLIHPKSGRSY-HEEFNP---------PKEPMKDDITGEPLIRR 175
Query: 205 EQEEEEAFIAEMQ 217
+ E+A +Q
Sbjct: 176 SDDNEKALKIRLQ 188
>gi|7524346 adenylate kinase 2 isoform b [Homo sapiens]
Length = 232
Score = 61.6 bits (148), Expect = 1e-09
Identities = 49/193 (25%), Positives = 92/193 (47%), Gaps = 22/193 (11%)
Query: 29 KPVCFVVFGKPGVGKTTLARYITQAWKCIRVEALPILEEQIAAETESGVMLQSMLISGQS 88
K + V+ G PG GK T A + + + + +L +A+ +E G L++ + +G+
Sbjct: 14 KGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKL 73
Query: 89 IPDELVIKLMLEKLNSPEVCHFGYIITEIPSLSQDAMTTLQQIELIKNL----NLKPDVI 144
+ DE+V++L+ + L +P +C G+++ P T++Q E++ +L K D +
Sbjct: 74 VSDEMVVELIEKNLETP-LCKNGFLLDGFP-------RTVRQAEMLDDLMEKRKEKLDSV 125
Query: 145 INIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEE 204
I PD L +RI+G+ H +G Y ++++P KE KD E
Sbjct: 126 IEFSIPDSLLIRRITGRLIHPKSGRSY-HEEFNP---------PKEPMKDDITGEPLIRR 175
Query: 205 EQEEEEAFIAEMQ 217
+ E+A +Q
Sbjct: 176 SDDNEKALKIRLQ 188
>gi|53832001 adenylate kinase 3-like 1 isoform 7 [Homo sapiens]
Length = 223
Score = 57.8 bits (138), Expect = 2e-08
Identities = 52/202 (25%), Positives = 93/202 (46%), Gaps = 13/202 (6%)
Query: 26 LLSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVEALPILEEQIAAETESGVMLQSMLIS 85
+ SK + V+ G PG GK T+ + I Q + + + L E I A TE G M + +
Sbjct: 1 MASKLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEK 60
Query: 86 GQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSLSQDAMTTLQQIELIKNLNLKPDVII 145
+PD ++ +LM+ +L + H +++ P TL Q E + + + D++I
Sbjct: 61 SLLVPDHVITRLMMSELENRRGQH--WLLDGFP-------RTLGQAEALDKI-CEVDLVI 110
Query: 146 NIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEV--IENHRKKKKEAQKDGKGEEEEEE 203
++ P L R+S + H +G +Y+ D P V I++ + Q+D K E
Sbjct: 111 SLNIPFETLKDRLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAAR 170
Query: 204 EEQEEEEAF-IAEMQMVAEILH 224
Q ++ A + E+ +LH
Sbjct: 171 LRQYKDVAKPVIELYKSRGVLH 192
>gi|53832003 adenylate kinase 3-like 1 isoform 5 [Homo sapiens]
Length = 223
Score = 57.8 bits (138), Expect = 2e-08
Identities = 52/202 (25%), Positives = 93/202 (46%), Gaps = 13/202 (6%)
Query: 26 LLSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVEALPILEEQIAAETESGVMLQSMLIS 85
+ SK + V+ G PG GK T+ + I Q + + + L E I A TE G M + +
Sbjct: 1 MASKLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEK 60
Query: 86 GQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSLSQDAMTTLQQIELIKNLNLKPDVII 145
+PD ++ +LM+ +L + H +++ P TL Q E + + + D++I
Sbjct: 61 SLLVPDHVITRLMMSELENRRGQH--WLLDGFP-------RTLGQAEALDKI-CEVDLVI 110
Query: 146 NIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEV--IENHRKKKKEAQKDGKGEEEEEE 203
++ P L R+S + H +G +Y+ D P V I++ + Q+D K E
Sbjct: 111 SLNIPFETLKDRLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAAR 170
Query: 204 EEQEEEEAF-IAEMQMVAEILH 224
Q ++ A + E+ +LH
Sbjct: 171 LRQYKDVAKPVIELYKSRGVLH 192
>gi|8051579 adenylate kinase 3-like 1 isoform 6 [Homo sapiens]
Length = 223
Score = 57.8 bits (138), Expect = 2e-08
Identities = 52/202 (25%), Positives = 93/202 (46%), Gaps = 13/202 (6%)
Query: 26 LLSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVEALPILEEQIAAETESGVMLQSMLIS 85
+ SK + V+ G PG GK T+ + I Q + + + L E I A TE G M + +
Sbjct: 1 MASKLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEK 60
Query: 86 GQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSLSQDAMTTLQQIELIKNLNLKPDVII 145
+PD ++ +LM+ +L + H +++ P TL Q E + + + D++I
Sbjct: 61 SLLVPDHVITRLMMSELENRRGQH--WLLDGFP-------RTLGQAEALDKI-CEVDLVI 110
Query: 146 NIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEV--IENHRKKKKEAQKDGKGEEEEEE 203
++ P L R+S + H +G +Y+ D P V I++ + Q+D K E
Sbjct: 111 SLNIPFETLKDRLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAAR 170
Query: 204 EEQEEEEAF-IAEMQMVAEILH 224
Q ++ A + E+ +LH
Sbjct: 171 LRQYKDVAKPVIELYKSRGVLH 192
>gi|19923437 adenylate kinase 3 [Homo sapiens]
Length = 227
Score = 55.5 bits (132), Expect = 9e-08
Identities = 36/148 (24%), Positives = 76/148 (51%), Gaps = 10/148 (6%)
Query: 34 VVFGKPGVGKTTLARYITQAWKCIRVEALPILEEQIAAETESGVMLQSMLISGQSIPDEL 93
V+ G PG GK T++ IT ++ + + +L + + TE GV+ ++ + G+ IPD++
Sbjct: 11 VIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIPDDV 70
Query: 94 VIKLMLEKLNSPEVCHFGYIITEIPSLSQDAMTTLQQIELIKNLNLKPDVIINIKCPDYD 153
+ +L L +L + + + +++ P TL Q E + + D +IN+ P
Sbjct: 71 MTRLALHELKN--LTQYSWLLDGFP-------RTLPQAEALDRA-YQIDTVINLNVPFEV 120
Query: 154 LCQRISGQRQHNNTGYIYSRDQWDPEVI 181
+ QR++ + H +G +Y+ + P+ +
Sbjct: 121 IKQRLTARWIHPASGRVYNIEFNPPKTV 148
>gi|22749187 putative adenylate kinase-like protein C9orf98 [Homo
sapiens]
Length = 479
Score = 55.1 bits (131), Expect = 1e-07
Identities = 42/149 (28%), Positives = 71/149 (47%), Gaps = 15/149 (10%)
Query: 34 VVFGKPGVGKTTLARYITQAWKCIRVEA-LPILEEQIAAE-TESGVMLQSMLISGQSIPD 91
V+ G P GKTT+A W C + + L LE I E + + + + + +++P
Sbjct: 61 VILGPPASGKTTIAM-----WLCKHLNSSLLTLENLILNEFSYTATEARRLYLQRKTVPS 115
Query: 92 ELVIKLMLEKLNSPEVCHFGYIITEIPSLSQDAMTTLQQIELIKNLNLKPDVIINIKCPD 151
L+++L+ E+L + G+I+ IP + A+ I+ L + P +I + PD
Sbjct: 116 ALLVQLIQERLAEEDCIKQGWILDGIPETREQALR-------IQTLGITPRHVIVLSAPD 168
Query: 152 YDLCQRISGQRQHNNTGYIY-SRDQWDPE 179
L +R G+R TG IY + W PE
Sbjct: 169 TVLIERNLGKRIDPQTGEIYHTTFDWPPE 197
Score = 53.9 bits (128), Expect = 3e-07
Identities = 39/178 (21%), Positives = 80/178 (44%), Gaps = 11/178 (6%)
Query: 9 EYPFADIFDEDET--ERNFLLSKPVC--FVVFGKPGVGKTTLARYITQAWKCIRVEALPI 64
+ P D+F + T + N + P ++ G G GK+ A + Q ++ + V +
Sbjct: 243 DQPCVDVFYQALTYVQSNHRTNAPFTPRVLLLGPVGSGKSLQAALLAQKYRLVNVCCGQL 302
Query: 65 LEEQIAAETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSLSQDA 124
L+E +A T G ++Q ++PD L++K++ ++L+ + G+++ +P
Sbjct: 303 LKEAVADRTTFGELIQPFFEKEMAVPDSLLMKVLSQRLDQQDCIQKGWVLHGVP------ 356
Query: 125 MTTLQQIELIKNLNLKPDVIINIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEVIE 182
L Q L+ L P+ + + P + +R++ +R TG Y P +E
Sbjct: 357 -RDLDQAHLLNRLGYNPNRVFFLNVPFDSIMERLTLRRIDPVTGERYHLMYKPPPTME 413
>gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens]
Length = 562
Score = 42.4 bits (98), Expect = 8e-04
Identities = 26/107 (24%), Positives = 54/107 (50%), Gaps = 3/107 (2%)
Query: 14 DIFDEDETERNFLLSKPVCFVVF--GKPGVGKTTLARYITQAWKCIRVEALPILEEQIAA 71
++F ED T F+ C ++F G PG GK T + + + + +L E++A+
Sbjct: 359 NVFGED-TMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELAS 417
Query: 72 ETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIP 118
E+E +++ ++ G +P +V++L+ E + + G++I P
Sbjct: 418 ESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYP 464
>gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens]
Length = 536
Score = 42.4 bits (98), Expect = 8e-04
Identities = 26/107 (24%), Positives = 54/107 (50%), Gaps = 3/107 (2%)
Query: 14 DIFDEDETERNFLLSKPVCFVVF--GKPGVGKTTLARYITQAWKCIRVEALPILEEQIAA 71
++F ED T F+ C ++F G PG GK T + + + + +L E++A+
Sbjct: 333 NVFGED-TMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELAS 391
Query: 72 ETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIP 118
E+E +++ ++ G +P +V++L+ E + + G++I P
Sbjct: 392 ESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYP 438
>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
sapiens]
Length = 1251
Score = 41.6 bits (96), Expect = 0.001
Identities = 39/154 (25%), Positives = 70/154 (45%), Gaps = 9/154 (5%)
Query: 66 EEQIAAETESGVMLQSMLISGQSIPDELVIKLM--LEKLNSPEVCHFGYIITEIPSLSQD 123
+E A E + G Q+ + P LV ++ LE V H G I + P
Sbjct: 228 KEAPAPEPQPGSQAQTSSLPPTRDPARLVAWVLHRLEMALPQPVLH-GKIGEQEPD--SP 284
Query: 124 AMTTLQQIELIKNLNLKPDVIIN-IKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEVIE 182
+ +Q I ++ ++PD+++ ++ P D Q +S Q Y + + +E
Sbjct: 285 GICDVQTISILPGGQVEPDLVLEEVEPPWEDAHQDVSTSPQGTEVVPAYEEEN---KAVE 341
Query: 183 NHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEM 216
++ +++ + EEEEEEEE+EEEE + E+
Sbjct: 342 KMPRELSRIEEEKEDEEEEEEEEEEEEEEEVTEV 375
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 41.2 bits (95), Expect = 0.002
Identities = 24/63 (38%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 151 DYDLCQRISGQRQHNNTGYI---YSRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQE 207
D++ S Q NNT D + E +E ++ +E +DG+ EEEEEEEE+E
Sbjct: 182 DHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEE 241
Query: 208 EEE 210
EEE
Sbjct: 242 EEE 244
Score = 32.0 bits (71), Expect = 1.1
Identities = 13/37 (35%), Positives = 26/37 (70%)
Query: 174 DQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEE 210
D + E ++ ++++E +++ + EEEEEEEE E++E
Sbjct: 218 DAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDE 254
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 41.2 bits (95), Expect = 0.002
Identities = 24/63 (38%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 151 DYDLCQRISGQRQHNNTGYI---YSRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQE 207
D++ S Q NNT D + E +E ++ +E +DG+ EEEEEEEE+E
Sbjct: 182 DHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEE 241
Query: 208 EEE 210
EEE
Sbjct: 242 EEE 244
Score = 32.0 bits (71), Expect = 1.1
Identities = 13/37 (35%), Positives = 26/37 (70%)
Query: 174 DQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEE 210
D + E ++ ++++E +++ + EEEEEEEE E++E
Sbjct: 218 DAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDE 254
>gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens]
Length = 1012
Score = 40.8 bits (94), Expect = 0.002
Identities = 34/145 (23%), Positives = 70/145 (48%), Gaps = 10/145 (6%)
Query: 177 DPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVA-----EILHHLVQRPE 231
+PE+ E+ ++ ++E+++D K +EE +E +E+ + +++ E +H
Sbjct: 840 EPEIDESFKEDEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFET 899
Query: 232 DYLENVENIVKLYKETILQTLEEVMA--EHNPQYLIEL-NGNKPAEELFMIVMDRLKYLN 288
D L + K + T+ Q E MA EH + L+E+ N + AEE F ++L +
Sbjct: 900 DVLSSWRESAK--QGTLAQKYLEAMAVIEHMQEKLLEVENRARQAEEKFEDAYEKLHHTL 957
Query: 289 LKRAAILTKLQGAEEEINDTMENDE 313
+K + + + +E + EN +
Sbjct: 958 IKNKDLEELVMTSRKESKEEKENQD 982
Score = 32.7 bits (73), Expect = 0.63
Identities = 15/36 (41%), Positives = 24/36 (66%)
Query: 180 VIENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAE 215
V+ + ++ K+E + + E +EEEE+QEEEE AE
Sbjct: 967 VMTSRKESKEEKENQDEREVKEEEEQQEEEEVRSAE 1002
Score = 31.6 bits (70), Expect = 1.4
Identities = 14/32 (43%), Positives = 22/32 (68%)
Query: 179 EVIENHRKKKKEAQKDGKGEEEEEEEEQEEEE 210
E++ RK+ KE +++ E +EEEEQ+EEE
Sbjct: 965 ELVMTSRKESKEEKENQDEREVKEEEEQQEEE 996
>gi|24308223 hypothetical protein LOC57577 [Homo sapiens]
Length = 936
Score = 40.0 bits (92), Expect = 0.004
Identities = 34/137 (24%), Positives = 64/137 (46%), Gaps = 15/137 (10%)
Query: 185 RKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENIVKLY 244
+KKK+E +K + + +EEE ++ E E A+++ +R E L+ ++ + K
Sbjct: 678 KKKKQEEEKLAQLKAQEEERQKREAEEKEAQLER---------KREEKRLKKMKELEKQK 728
Query: 245 KETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKY------LNLKRAAILTKL 298
+ Q LE + EH + L+ G +P + L M ++ L L+R +LT
Sbjct: 729 RIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWF 788
Query: 299 QGAEEEINDTMENDELF 315
Q ++E + M + F
Sbjct: 789 QRSQESLARKMAQADQF 805
>gi|118600967 shroom family member 4 [Homo sapiens]
Length = 1493
Score = 39.7 bits (91), Expect = 0.005
Identities = 26/95 (27%), Positives = 47/95 (49%), Gaps = 6/95 (6%)
Query: 182 ENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENIV 241
+ +++++E +++ + EEEEEEEE EEEE + +E PE+ LE + +
Sbjct: 1128 QKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSETSGSCALNPEEVLEQPQPLS 1187
Query: 242 KLYKETILQTLEEVMAE------HNPQYLIELNGN 270
+ E Q + V AE H+ +L + G+
Sbjct: 1188 FGHLEGSRQGSQSVPAEQESFALHSSDFLPPIRGH 1222
Score = 34.7 bits (78), Expect = 0.17
Identities = 15/35 (42%), Positives = 24/35 (68%)
Query: 176 WDPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEE 210
W+ + +++K+ Q+ K +EEEEEEE+EEEE
Sbjct: 1109 WEKYRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEE 1143
Score = 33.5 bits (75), Expect = 0.37
Identities = 14/26 (53%), Positives = 22/26 (84%)
Query: 185 RKKKKEAQKDGKGEEEEEEEEQEEEE 210
+++K++ Q+ + EEEEEEEE+EEEE
Sbjct: 1119 QQQKQQQQQQKQQEEEEEEEEEEEEE 1144
Score = 31.6 bits (70), Expect = 1.4
Identities = 12/29 (41%), Positives = 23/29 (79%)
Query: 182 ENHRKKKKEAQKDGKGEEEEEEEEQEEEE 210
+ ++++++ ++ + EEEEEEEE+EEEE
Sbjct: 1119 QQQKQQQQQQKQQEEEEEEEEEEEEEEEE 1147
>gi|148727333 adenylate kinase 7 [Homo sapiens]
Length = 723
Score = 39.3 bits (90), Expect = 0.007
Identities = 62/304 (20%), Positives = 111/304 (36%), Gaps = 77/304 (25%)
Query: 30 PVCFVVFGKPGVGKTTLARYITQAWKCIRVEALPILEEQIA------------------- 70
P+ + G P VGK+++A+ + +K ++ ++ E IA
Sbjct: 367 PIKICILGPPAVGKSSIAKELANYYKLHHIQLKDVISEAIAKLEAIVAPNDVGEGEEEVE 426
Query: 71 -AETESGV---------MLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSL 120
E E V + +SM + + D+ +I+ M EKL S + GYI+ P
Sbjct: 427 EEEEEENVEDAQELLDGIKESMEQNAGQLDDQYIIRFMKEKLKSMPCRNQGYILDGFPKT 486
Query: 121 SQDAMTTLQQIELIKNLNLK-----------PDVIINIKCPDYDLCQRISGQRQHNNTGY 169
A Q + + +++ P+ + + D L +R+ + G
Sbjct: 487 YDQAKDLFNQEDEEEEDDVRGRMFPFDKLIIPEFVCALDASDEFLKERVINLPESIVAGT 546
Query: 170 IYSRDQW------------DPEVIENHRK------------KKKEAQK--------DGKG 197
YS+D++ D E + N+ K ++AQ G
Sbjct: 547 HYSQDRFLRALSNYRDINIDDETVFNYFDELEIHPIHIDVGKLEDAQNRLAIKQLIKEIG 606
Query: 198 EEEE---EEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENIVKLYKETILQTLEE 254
E +EE+ EEE AE ++ E + ++ +E E I + E + LEE
Sbjct: 607 EPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARW--EEWNKRLEE 664
Query: 255 VMAE 258
V E
Sbjct: 665 VKRE 668
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 38.9 bits (89), Expect = 0.009
Identities = 33/139 (23%), Positives = 62/139 (44%), Gaps = 11/139 (7%)
Query: 176 WDPEVIENHRKKKKEAQKDGKGEEE----EEEEEQEEEEAFIAEMQMVAEILHHLVQRPE 231
WD E ++ +E +K + EEE +EE+ QE+EE + + + E + ++ E
Sbjct: 550 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609
Query: 232 DYLENVENIVKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKR 291
E E + + +E +Q EE+M E + + EE ++++ K
Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKM-------QEQEEKMWEQEEKMREQEEKM 662
Query: 292 AAILTKLQGAEEEINDTME 310
K+QG EE++ + E
Sbjct: 663 REQEEKMQGQEEKMREQEE 681
Score = 32.3 bits (72), Expect = 0.83
Identities = 31/153 (20%), Positives = 65/153 (42%), Gaps = 3/153 (1%)
Query: 161 QRQHNNTGYIYSRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQ---EEEEAFIAEMQ 217
Q Q T + + + + E +K ++E + + EE+ +E+E+ E+EE + +
Sbjct: 543 QEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEE 602
Query: 218 MVAEILHHLVQRPEDYLENVENIVKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELF 277
+ E + ++ E E E +E ++ EE M E + + + EE
Sbjct: 603 KMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM 662
Query: 278 MIVMDRLKYLNLKRAAILTKLQGAEEEINDTME 310
++++ K K+QG EE++ + E
Sbjct: 663 REQEEKMQGQEEKMREQEEKMQGQEEKMREQEE 695
Score = 29.6 bits (65), Expect = 5.4
Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 5/106 (4%)
Query: 173 RDQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQ---EEEEAFIAEMQMVAEILHHLVQR 229
+ W E KK +E +K +EE+ EE+ E E+ E +M+ E + ++
Sbjct: 527 KKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQ 586
Query: 230 PEDYLENVENIVKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEE 275
E E E + + +E +Q EE M E + + +K E+
Sbjct: 587 EEKMREQEEKMWE--QEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQ 630
>gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens]
Length = 841
Score = 38.9 bits (89), Expect = 0.009
Identities = 36/146 (24%), Positives = 63/146 (43%), Gaps = 9/146 (6%)
Query: 184 HRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAE---MQMVAEILHHLVQRPEDYLENVENI 240
+ ++ +E +D K +EEE + EE+A E +Q E L V + E
Sbjct: 469 YERELRELHEDKKRQEEELRGQIREEKARTRELETLQQTVEELQAQVHSMDGAKGWFERR 528
Query: 241 VKLYKETI---LQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKRAAILTK 297
+K +E++ Q EE + + Q+ EL G EE V D+L+ +R L
Sbjct: 529 LKEAEESLQQQQQEQEEALKQCREQHAAELKGK---EEELQDVRDQLEQAQEERDCHLKT 585
Query: 298 LQGAEEEINDTMENDELFRTLASYKL 323
+ ++E+ DT++ + S L
Sbjct: 586 ISSLKQEVKDTVDGQRILEKKGSAAL 611
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 38.5 bits (88), Expect = 0.012
Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 16/142 (11%)
Query: 76 GVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSLSQDAMTTLQQIELIK 135
G++ S+L GQ I +E +++ L + P I L Q+A E K
Sbjct: 162 GIIATSLLNLGQ-IAEETLVEEDLGQAAKPG--------PGIVHLLQEAAEGAASEEGEK 212
Query: 136 NLNLKPD----VIINIKCPDYDLCQRI---SGQRQHNNTGYIYSRDQWDPEVIENHRKKK 188
L ++P+ V+ DLC + + + + I S ++ D E E +++
Sbjct: 213 GLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEE 272
Query: 189 KEAQKDGKGEEEEEEEEQEEEE 210
++ +++ + EEEEEEEE+EEEE
Sbjct: 273 EDEEEEEEEEEEEEEEEEEEEE 294
Score = 36.6 bits (83), Expect = 0.044
Identities = 16/38 (42%), Positives = 28/38 (73%)
Query: 174 DQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEEA 211
++ + E E ++++E +++ + EEEEEEEE+EEEEA
Sbjct: 270 EEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEA 307
Score = 35.8 bits (81), Expect = 0.075
Identities = 16/37 (43%), Positives = 26/37 (70%)
Query: 174 DQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEE 210
D+ + E E + ++E +++ + EEEEEEEE+EEEE
Sbjct: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 297
Score = 35.8 bits (81), Expect = 0.075
Identities = 16/38 (42%), Positives = 27/38 (71%)
Query: 174 DQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEEA 211
++ D E E ++++E +++ + EEEEEEEE+EEE A
Sbjct: 271 EEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308
Score = 35.4 bits (80), Expect = 0.098
Identities = 15/37 (40%), Positives = 28/37 (75%)
Query: 174 DQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEE 210
++ + E E+ ++++E +++ + EEEEEEEE+EEEE
Sbjct: 265 EEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEE 301
Score = 35.0 bits (79), Expect = 0.13
Identities = 16/50 (32%), Positives = 32/50 (64%)
Query: 174 DQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEIL 223
++ + E E ++++E +++ + EEEEEEEE+EEEE E + +++
Sbjct: 263 EEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVI 312
Score = 35.0 bits (79), Expect = 0.13
Identities = 16/48 (33%), Positives = 29/48 (60%)
Query: 182 ENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQR 229
E ++++E +++ + EEEEEEEE+EEEE ++ + H Q+
Sbjct: 277 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQK 324
Score = 34.3 bits (77), Expect = 0.22
Identities = 15/37 (40%), Positives = 26/37 (70%)
Query: 174 DQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEE 210
++ + E E +++E +++ + EEEEEEEE+EEEE
Sbjct: 262 EEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEE 298
Score = 30.0 bits (66), Expect = 4.1
Identities = 13/42 (30%), Positives = 25/42 (59%)
Query: 174 DQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAE 215
D+ + E E ++++E +++ + EEEEEEEE+ + E
Sbjct: 274 DEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQE 315
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 38.1 bits (87), Expect = 0.015
Identities = 17/38 (44%), Positives = 28/38 (73%)
Query: 173 RDQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEE 210
R + + E + RK+KK+ +++ + EEEEEEEE++EEE
Sbjct: 52 RKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEE 89
Score = 37.4 bits (85), Expect = 0.026
Identities = 16/38 (42%), Positives = 28/38 (73%)
Query: 173 RDQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEE 210
+++ + E ++KKK+ +++ + EEEEEEEE+EEEE
Sbjct: 53 KEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEE 90
Score = 35.8 bits (81), Expect = 0.075
Identities = 16/26 (61%), Positives = 22/26 (84%)
Query: 185 RKKKKEAQKDGKGEEEEEEEEQEEEE 210
RKKKKE ++ + EEEEEEE++EEE+
Sbjct: 66 RKKKKEEEEREEEEEEEEEEKEEEEK 91
Score = 35.0 bits (79), Expect = 0.13
Identities = 14/26 (53%), Positives = 23/26 (88%)
Query: 185 RKKKKEAQKDGKGEEEEEEEEQEEEE 210
+KKK+E +++ + EEEEEE+E+EE+E
Sbjct: 67 KKKKEEEEREEEEEEEEEEKEEEEKE 92
Score = 32.7 bits (73), Expect = 0.63
Identities = 13/26 (50%), Positives = 23/26 (88%)
Query: 185 RKKKKEAQKDGKGEEEEEEEEQEEEE 210
+KK++E +++ + EEEEE+EE+E+EE
Sbjct: 68 KKKEEEEREEEEEEEEEEKEEEEKEE 93
Score = 31.2 bits (69), Expect = 1.8
Identities = 13/29 (44%), Positives = 21/29 (72%)
Query: 182 ENHRKKKKEAQKDGKGEEEEEEEEQEEEE 210
E ++K+KE +K K +E E+ +E+EEEE
Sbjct: 31 EKRKEKRKEKEKKKKTKETEKRKEKEEEE 59
Score = 31.2 bits (69), Expect = 1.8
Identities = 17/37 (45%), Positives = 22/37 (59%), Gaps = 8/37 (21%)
Query: 182 ENHRKKKKEAQ--------KDGKGEEEEEEEEQEEEE 210
E ++K+KE + K K EEE EEEE+EEEE
Sbjct: 48 ETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEE 84
Score = 30.0 bits (66), Expect = 4.1
Identities = 13/26 (50%), Positives = 20/26 (76%)
Query: 185 RKKKKEAQKDGKGEEEEEEEEQEEEE 210
+KKKK+ ++ + EE EE EE+EE+E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKE 26
>gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
Length = 406
Score = 38.1 bits (87), Expect = 0.015
Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 14/103 (13%)
Query: 177 DPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRP-EDYLE 235
+ EV + ++ +EA+ +GEEE EEEE EEEE + E + E H ++ P ++E
Sbjct: 311 EEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVE 370
Query: 236 NVENIVKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFM 278
E T L NP+ +I P E LFM
Sbjct: 371 AEEKRENFISCTFL----------NPEQIIP---KVPQESLFM 400
Score = 28.9 bits (63), Expect = 9.2
Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Query: 178 PEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENV 237
P ++E +KK + +++ E + +E EEEE E + V + V+ E E
Sbjct: 273 PLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGE 332
Query: 238 ENIVKLYKETILQTLEEVMAEH 259
E + +E L+ EEV+ E+
Sbjct: 333 EEL----EEEELEEEEEVLEEN 350
>gi|74315997 l-myc-1 proto-oncogene isoform 1 [Homo sapiens]
Length = 364
Score = 37.7 bits (86), Expect = 0.020
Identities = 22/95 (23%), Positives = 47/95 (49%), Gaps = 3/95 (3%)
Query: 115 TEIPSLSQDAMTTLQQIELIKNLNLKPDVIINIKCPDYDLCQR---ISGQRQHNNTGYIY 171
+E PS S++ + +E ++L ++ V I ++ D C + IS +Q +N +
Sbjct: 159 SESPSDSENEEIDVVTVEKRQSLGIRKPVTITVRADPLDPCMKHFHISIHQQQHNYAARF 218
Query: 172 SRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQ 206
+ E +++ ++D GE+E+EE+E+
Sbjct: 219 PPESCSQEEASERGPQEEVLERDAAGEKEDEEDEE 253
>gi|74315995 l-myc-1 proto-oncogene isoform 1 [Homo sapiens]
Length = 364
Score = 37.7 bits (86), Expect = 0.020
Identities = 22/95 (23%), Positives = 47/95 (49%), Gaps = 3/95 (3%)
Query: 115 TEIPSLSQDAMTTLQQIELIKNLNLKPDVIINIKCPDYDLCQR---ISGQRQHNNTGYIY 171
+E PS S++ + +E ++L ++ V I ++ D C + IS +Q +N +
Sbjct: 159 SESPSDSENEEIDVVTVEKRQSLGIRKPVTITVRADPLDPCMKHFHISIHQQQHNYAARF 218
Query: 172 SRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQ 206
+ E +++ ++D GE+E+EE+E+
Sbjct: 219 PPESCSQEEASERGPQEEVLERDAAGEKEDEEDEE 253
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 37.7 bits (86), Expect = 0.020
Identities = 15/29 (51%), Positives = 24/29 (82%)
Query: 182 ENHRKKKKEAQKDGKGEEEEEEEEQEEEE 210
E ++++E +++G+GEEEEEE E+EEEE
Sbjct: 407 EEEEEEEEEEEEEGEGEEEEEEGEEEEEE 435
Score = 31.2 bits (69), Expect = 1.8
Identities = 13/15 (86%), Positives = 15/15 (100%)
Query: 196 KGEEEEEEEEQEEEE 210
+GEEEEEEEE+EEEE
Sbjct: 404 EGEEEEEEEEEEEEE 418
Score = 29.6 bits (65), Expect = 5.4
Identities = 12/18 (66%), Positives = 16/18 (88%)
Query: 192 QKDGKGEEEEEEEEQEEE 209
+ +G+ EEEEEEEE+EEE
Sbjct: 402 KSEGEEEEEEEEEEEEEE 419
Score = 28.9 bits (63), Expect = 9.2
Identities = 13/23 (56%), Positives = 17/23 (73%)
Query: 188 KKEAQKDGKGEEEEEEEEQEEEE 210
K E +++ + EEEEEEEE E EE
Sbjct: 402 KSEGEEEEEEEEEEEEEEGEGEE 424
Score = 28.9 bits (63), Expect = 9.2
Identities = 13/28 (46%), Positives = 19/28 (67%)
Query: 182 ENHRKKKKEAQKDGKGEEEEEEEEQEEE 209
E + ++E ++ G+GEE EEEE EEE
Sbjct: 424 EEEEEGEEEEEEGGEGEELGEEEEVEEE 451
>gi|122937434 Rho-guanine nucleotide exchange factor [Homo sapiens]
Length = 1651
Score = 37.7 bits (86), Expect = 0.020
Identities = 38/167 (22%), Positives = 72/167 (43%), Gaps = 18/167 (10%)
Query: 169 YIYSRDQWDPEVIENHRKKKKEAQ--------------KDGKGEEEEEEEEQEEEEAFIA 214
++ S PE+ E H K+E ++ G E +E++ + EA +A
Sbjct: 1154 FLISASSAGPEMYEIHTNSKEERNNWMRRIQQAVESCPEEKGGRTSESDEDKRKAEARVA 1213
Query: 215 EMQMVAEILHHLVQRPEDYLENVENIVKLYKETILQTLEEVMAEHNPQYLIELNGNKPAE 274
++Q EIL + Q+ YLE +I E L E+V E P LI+ + +P +
Sbjct: 1214 KIQQCQEILTNQDQQICAYLEEKLHIYAELGE--LSGFEDVHLE--PHLLIKPDPGEPPQ 1269
Query: 275 ELFMIVMDRLKYLNLKRAAILTKLQGAEEEINDTMENDELFRTLASY 321
++ + +L+ A +++ + D+ + L TL+S+
Sbjct: 1270 AASLLAAALKEAESLQVAVKASQMGAVSQSCEDSCGDSVLADTLSSH 1316
>gi|20806097 nucleolar complex associated 3 homolog [Homo sapiens]
Length = 800
Score = 37.7 bits (86), Expect = 0.020
Identities = 42/183 (22%), Positives = 73/183 (39%), Gaps = 24/183 (13%)
Query: 194 DGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENIVKLYKETI----- 248
D +EE++EEE+E EE I + I HL++R + E +I L +
Sbjct: 172 DSNKDEEDQEEERELEEEIIEDPIQELTIEEHLIERKKKLQEKKMHIAALASAILSDPEN 231
Query: 249 ----LQTLEEVMAEHNPQYLIELNGNKPAE--ELFMIVMDRLKYLNLKRAAILTKLQGAE 302
L+ L ++ E +P + + ELF + K L A TK +
Sbjct: 232 NIKKLKELRSMLMEQDPDVAVTVRKLVIVSLMELFKDITPSYKIRPLTEAEKSTKTRKET 291
Query: 303 EEINDTMENDELFRTLASYKLIAPRYR-----WQRSKWGRTCPVNLKDGNIYSGLPDYSV 357
+++ + E ++ YK W++ K ++ V+LK Y GL + +V
Sbjct: 292 QKLREFEEG-----LVSQYKFYLENLEQMVKDWKQRKLKKSNVVSLK---AYKGLAEVAV 343
Query: 358 SFL 360
L
Sbjct: 344 KSL 346
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 37.4 bits (85), Expect = 0.026
Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 5/86 (5%)
Query: 179 EVIENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVE 238
E + + ++++E +++ + EE EEEE+ +EE E Q+ E ++ E E V+
Sbjct: 2241 ESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQ 2300
Query: 239 NIVKLYKETILQTLEEVMAEHNPQYL 264
KE + + EE+M+E + L
Sbjct: 2301 E-----KEEVFEEKEEIMSEEETESL 2321
Score = 29.6 bits (65), Expect = 5.4
Identities = 14/43 (32%), Positives = 29/43 (67%), Gaps = 1/43 (2%)
Query: 174 DQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQ-EEEEAFIAE 215
++ + + +E ++KK+ +K+ K EE +E+EE EE+E ++E
Sbjct: 2273 EEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSE 2315
Score = 28.9 bits (63), Expect = 9.2
Identities = 23/103 (22%), Positives = 48/103 (46%), Gaps = 7/103 (6%)
Query: 156 QRISGQRQHNNTGYIYSRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAE 215
Q+++ +++H I +W + R +KK AQ++ K +EEE+ QEE + E
Sbjct: 1559 QQVTEEQRH-----IQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEE 1613
Query: 216 MQMVAEILHHLVQRPEDYLENVENIVKLYKETILQTLEEVMAE 258
++ + + + + + E +ET+ Q E++ E
Sbjct: 1614 RKLAQAYVK--ITQDDREMAQAEGKFAQKEETLAQRGEKLSQE 1654
Score = 28.9 bits (63), Expect = 9.2
Identities = 19/73 (26%), Positives = 36/73 (49%)
Query: 182 ENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENIV 241
E R++++ +++ + +EEEE EE++ E+ + + E VQ E+ E E I+
Sbjct: 2254 EEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIM 2313
Query: 242 KLYKETILQTLEE 254
+ L EE
Sbjct: 2314 SEEETESLSDEEE 2326
>gi|4504425 high-mobility group box 1 [Homo sapiens]
Length = 215
Score = 37.4 bits (85), Expect = 0.026
Identities = 16/25 (64%), Positives = 21/25 (84%)
Query: 186 KKKKEAQKDGKGEEEEEEEEQEEEE 210
KKKKE ++D + EE+EEEEE EE+E
Sbjct: 182 KKKKEEEEDEEDEEDEEEEEDEEDE 206
Score = 33.9 bits (76), Expect = 0.28
Identities = 12/31 (38%), Positives = 25/31 (80%)
Query: 180 VIENHRKKKKEAQKDGKGEEEEEEEEQEEEE 210
V++ + KKK+ +++ + +EE+EEEE++EE+
Sbjct: 175 VVKAEKSKKKKEEEEDEEDEEDEEEEEDEED 205
Score = 33.1 bits (74), Expect = 0.49
Identities = 13/29 (44%), Positives = 22/29 (75%)
Query: 182 ENHRKKKKEAQKDGKGEEEEEEEEQEEEE 210
E +KKK+E + + E+EEEEE++E+E+
Sbjct: 179 EKSKKKKEEEEDEEDEEDEEEEEDEEDED 207
Score = 33.1 bits (74), Expect = 0.49
Identities = 13/26 (50%), Positives = 22/26 (84%)
Query: 185 RKKKKEAQKDGKGEEEEEEEEQEEEE 210
+K+++E ++D + EEEEE+EE E+EE
Sbjct: 184 KKEEEEDEEDEEDEEEEEDEEDEDEE 209
Score = 30.0 bits (66), Expect = 4.1
Identities = 14/38 (36%), Positives = 24/38 (63%)
Query: 173 RDQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEE 210
R + P+ + K ++++K + EE+EE+EE EEEE
Sbjct: 163 RAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEE 200
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.135 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,448,757
Number of Sequences: 37866
Number of extensions: 889039
Number of successful extensions: 19304
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 360
Number of HSP's successfully gapped in prelim test: 214
Number of HSP's that attempted gapping in prelim test: 11444
Number of HSP's gapped (non-prelim): 4463
length of query: 421
length of database: 18,247,518
effective HSP length: 105
effective length of query: 316
effective length of database: 14,271,588
effective search space: 4509821808
effective search space used: 4509821808
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.