Guide to the Human Genome
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Name: RGNEF Sequence: fasta or formatted (1651aa) NCBI GI: 122937434
Description:

Rho-guanine nucleotide exchange factor

Referenced in:

Rho and Rac

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.9         98           3
 C cysteine            2.2         37           2
 D aspartate           4.7         78           1
 E glutamate           9.4        155           3
 F phenylalanine       3.1         52           2
 G glycine             5.0         82           2
 H histidine           3.5         57           2
 I isoleucine          4.0         66           2
 K lysine              5.5         91           2
 L leucine            11.1        183           3
 M methionine          1.8         30           2
 N asparagine          3.6         59           2
 P proline             4.1         68           2
 Q glutamine           6.1        100           3
 R arginine            5.8         96           3
 S serine             11.2        185           3
 T threonine           4.8         79           2
 V valine              5.2         86           2
 W tryptophan          1.0         16           1
 Y tyrosine            2.0         33           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Rho-guanine nucleotide exchange factor 
ARHGEF18              0.188   Rho/Rac guanine nucleotide exchange factor 18 isofo...
ARHGEF18              0.188   Rho/Rac guanine nucleotide exchange factor 18 isofor...
AKAP13                0.173   A-kinase anchor protein 13 isoform 2 
AKAP13                0.173   A-kinase anchor protein 13 isoform 1 
AKAP13                0.167   A-kinase anchor protein 13 isoform 3 
ARHGEF2               0.150   Rho/Rac guanine nucleotide exchange factor 2 isofor...
ARHGEF2               0.149   Rho/Rac guanine nucleotide exchange factor 2 isofor...
ARHGEF2               0.148   Rho/Rac guanine nucleotide exchange factor 2 isoofor...
ARHGEF11              0.044   Rho guanine nucleotide exchange factor (GEF) 11 isof...
ARHGEF11              0.044   Rho guanine nucleotide exchange factor (GEF) 11 isofo...
ARHGEF12              0.044   Rho guanine nucleotide exchange factor (GEF) 12 [Homo...
ARHGEF1               0.038   Rho guanine nucleotide exchange factor 1 isoform 1 [...
ARHGEF1               0.038   Rho guanine nucleotide exchange factor 1 isoform 3 [...
ARHGEF1               0.038   Rho guanine nucleotide exchange factor 1 isoform 2 [...
ITSN2                 0.019   intersectin 2 isoform 3 
ITSN2                 0.019   intersectin 2 isoform 1 
ITSN1                 0.017   intersectin 1 isoform ITSN-l 
ARHGEF17              0.016   Rho guanine nucleotide exchange factor (GEF) 17 [Hom...
ARHGEF3               0.016   Rho guanine nucleotide exchange factor 3 isoform 1 ...
ARHGEF3               0.015   Rho guanine nucleotide exchange factor 3 isoform 2 ...
ARHGEF3               0.015   Rho guanine nucleotide exchange factor 3 isoform 3 [H...
TIAM2                 0.014   T-cell lymphoma invasion and metastasis 2 isoform a ...
FLJ41603              0.013   hypothetical protein LOC389337 
NET1                  0.013   neuroepithelial cell transforming gene 1 isoform 1 ...
NET1                  0.013   neuroepithelial cell transforming gene 1 isoform 2 [...
TIAM2                 0.013   T-cell lymphoma invasion and metastasis 2 isoform b ...
ARHGEF16              0.013   Rho guanine exchange factor 16 
FGD1                  0.013   faciogenital dysplasia protein 
PREX2                 0.012   DEP domain containing 2 isoform b 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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