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Search of human proteins with 21389589
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21389589 transmembrane channel-like 4 isoform 2 [Homo
sapiens]
(706 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21389589 transmembrane channel-like 4 isoform 2 [Homo sapiens] 1413 0.0
gi|223718080 transmembrane channel-like 4 isoform 1 [Homo sapiens] 1406 0.0
gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens] 434 e-121
gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens] 432 e-121
gi|23943900 transmembrane channel-like 8 [Homo sapiens] 332 9e-91
gi|157426860 transmembrane channel-like 5 isoform a [Homo sapiens] 182 1e-45
gi|31377679 transmembrane channel-like 5 isoform c [Homo sapiens] 182 1e-45
gi|21071070 transmembrane channel-like 1 [Homo sapiens] 176 5e-44
gi|94536852 transmembrane cochlear-expressed protein 2 [Homo sap... 172 1e-42
gi|157426862 transmembrane channel-like 5 isoform b [Homo sapiens] 164 3e-40
gi|187608784 transmembrane channel-like 6 [Homo sapiens] 149 9e-36
gi|187608791 transmembrane channel-like 6 [Homo sapiens] 149 9e-36
gi|122937502 transmembrane channel-like 3 [Homo sapiens] 122 1e-27
gi|122937243 dual specificity phosphatase 27 [Homo sapiens] 37 0.082
gi|222352177 nuclear factor of kappa light polypeptide gene enha... 35 0.31
gi|222352173 nuclear factor of kappa light polypeptide gene enha... 35 0.31
gi|222352179 nuclear factor of kappa light polypeptide gene enha... 34 0.41
gi|222352175 nuclear factor of kappa light polypeptide gene enha... 34 0.41
gi|195927059 axin 2 [Homo sapiens] 32 1.5
gi|33589848 transferrin receptor 2 [Homo sapiens] 32 1.5
gi|166795252 hypothetical protein LOC23359 [Homo sapiens] 32 2.6
gi|31881740 solute carrier family 12 (potassium/chloride transpo... 32 2.6
gi|41349499 proteolipid protein 1 isoform 1 [Homo sapiens] 31 3.4
gi|192449447 proteolipid protein 1 isoform 1 [Homo sapiens] 31 3.4
gi|239757751 PREDICTED: hypothetical protein [Homo sapiens] 31 3.4
gi|239752261 PREDICTED: hypothetical protein XP_002348184 [Homo ... 31 3.4
gi|239746774 PREDICTED: hypothetical protein XP_002343845 [Homo ... 31 3.4
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 31 3.4
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 31 3.4
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] 31 3.4
>gi|21389589 transmembrane channel-like 4 isoform 2 [Homo sapiens]
Length = 706
Score = 1413 bits (3657), Expect = 0.0
Identities = 706/706 (100%), Positives = 706/706 (100%)
Query: 1 MEENPTLESEAWGSSRGWLAPREARGGPSLSSVLNELPSAATLRYRDPGVLPWGALEEEE 60
MEENPTLESEAWGSSRGWLAPREARGGPSLSSVLNELPSAATLRYRDPGVLPWGALEEEE
Sbjct: 1 MEENPTLESEAWGSSRGWLAPREARGGPSLSSVLNELPSAATLRYRDPGVLPWGALEEEE 60
Query: 61 EDGGRSRKAFTEVTQTELQDPHPSRELPWPMQARRAHRQRNASRDQVVYGSGTKTDRWAR 120
EDGGRSRKAFTEVTQTELQDPHPSRELPWPMQARRAHRQRNASRDQVVYGSGTKTDRWAR
Sbjct: 61 EDGGRSRKAFTEVTQTELQDPHPSRELPWPMQARRAHRQRNASRDQVVYGSGTKTDRWAR 120
Query: 121 LLRRSKEKTKEGLRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTL 180
LLRRSKEKTKEGLRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTL
Sbjct: 121 LLRRSKEKTKEGLRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTL 180
Query: 181 LPTWLGGAPPGPPGPDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPP 240
LPTWLGGAPPGPPGPDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPP
Sbjct: 181 LPTWLGGAPPGPPGPDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPP 240
Query: 241 RPRLAVTYLCWAFAVGLICLLLILHRSVSGLKQTLLAESEALTSYSHRVFSAWDFGLCGD 300
RPRLAVTYLCWAFAVGLICLLLILHRSVSGLKQTLLAESEALTSYSHRVFSAWDFGLCGD
Sbjct: 241 RPRLAVTYLCWAFAVGLICLLLILHRSVSGLKQTLLAESEALTSYSHRVFSAWDFGLCGD 300
Query: 301 VHVRLRQRIILYELKVELEETVVRRQAAVRTLGQQARVWLVRVLLNLLVVALLGAAFYGV 360
VHVRLRQRIILYELKVELEETVVRRQAAVRTLGQQARVWLVRVLLNLLVVALLGAAFYGV
Sbjct: 301 VHVRLRQRIILYELKVELEETVVRRQAAVRTLGQQARVWLVRVLLNLLVVALLGAAFYGV 360
Query: 361 YWATGCTVELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLIAPLEGYTRSRQI 420
YWATGCTVELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLIAPLEGYTRSRQI
Sbjct: 361 YWATGCTVELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLIAPLEGYTRSRQI 420
Query: 421 VFILLRTVFLRLASLVVLLFSLWNQITCGGDSEAEDCKTCGYNYKQLPCWETVLGQEMYK 480
VFILLRTVFLRLASLVVLLFSLWNQITCGGDSEAEDCKTCGYNYKQLPCWETVLGQEMYK
Sbjct: 421 VFILLRTVFLRLASLVVLLFSLWNQITCGGDSEAEDCKTCGYNYKQLPCWETVLGQEMYK 480
Query: 481 LLLFDLLTVLAVALLIQFPRKLLCGLCPGALGRLAGTQEFQVPDEVLGLIYAQTVVWVGS 540
LLLFDLLTVLAVALLIQFPRKLLCGLCPGALGRLAGTQEFQVPDEVLGLIYAQTVVWVGS
Sbjct: 481 LLLFDLLTVLAVALLIQFPRKLLCGLCPGALGRLAGTQEFQVPDEVLGLIYAQTVVWVGS 540
Query: 541 FFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANFFFPLVLLLGLAISSVPL 600
FFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANFFFPLVLLLGLAISSVPL
Sbjct: 541 FFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANFFFPLVLLLGLAISSVPL 600
Query: 601 LYSIFLIPPSKLCGPFRGQSSIWAQIPESISSLPETTQNFLFFLGTQAFAVPLLLISSIL 660
LYSIFLIPPSKLCGPFRGQSSIWAQIPESISSLPETTQNFLFFLGTQAFAVPLLLISSIL
Sbjct: 601 LYSIFLIPPSKLCGPFRGQSSIWAQIPESISSLPETTQNFLFFLGTQAFAVPLLLISSIL 660
Query: 661 MAYTVALANSYGRLISELKRQRQTEAQNKVFLARRAVALTSTKPAL 706
MAYTVALANSYGRLISELKRQRQTEAQNKVFLARRAVALTSTKPAL
Sbjct: 661 MAYTVALANSYGRLISELKRQRQTEAQNKVFLARRAVALTSTKPAL 706
>gi|223718080 transmembrane channel-like 4 isoform 1 [Homo sapiens]
Length = 712
Score = 1406 bits (3640), Expect = 0.0
Identities = 706/712 (99%), Positives = 706/712 (99%), Gaps = 6/712 (0%)
Query: 1 MEENPTLESEAWGSSRGWLAPREARG------GPSLSSVLNELPSAATLRYRDPGVLPWG 54
MEENPTLESEAWGSSRGWLAPREARG GPSLSSVLNELPSAATLRYRDPGVLPWG
Sbjct: 1 MEENPTLESEAWGSSRGWLAPREARGAPCSSPGPSLSSVLNELPSAATLRYRDPGVLPWG 60
Query: 55 ALEEEEEDGGRSRKAFTEVTQTELQDPHPSRELPWPMQARRAHRQRNASRDQVVYGSGTK 114
ALEEEEEDGGRSRKAFTEVTQTELQDPHPSRELPWPMQARRAHRQRNASRDQVVYGSGTK
Sbjct: 61 ALEEEEEDGGRSRKAFTEVTQTELQDPHPSRELPWPMQARRAHRQRNASRDQVVYGSGTK 120
Query: 115 TDRWARLLRRSKEKTKEGLRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVL 174
TDRWARLLRRSKEKTKEGLRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVL
Sbjct: 121 TDRWARLLRRSKEKTKEGLRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVL 180
Query: 175 MACMTLLPTWLGGAPPGPPGPDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLF 234
MACMTLLPTWLGGAPPGPPGPDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLF
Sbjct: 181 MACMTLLPTWLGGAPPGPPGPDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLF 240
Query: 235 YGFYPPRPRLAVTYLCWAFAVGLICLLLILHRSVSGLKQTLLAESEALTSYSHRVFSAWD 294
YGFYPPRPRLAVTYLCWAFAVGLICLLLILHRSVSGLKQTLLAESEALTSYSHRVFSAWD
Sbjct: 241 YGFYPPRPRLAVTYLCWAFAVGLICLLLILHRSVSGLKQTLLAESEALTSYSHRVFSAWD 300
Query: 295 FGLCGDVHVRLRQRIILYELKVELEETVVRRQAAVRTLGQQARVWLVRVLLNLLVVALLG 354
FGLCGDVHVRLRQRIILYELKVELEETVVRRQAAVRTLGQQARVWLVRVLLNLLVVALLG
Sbjct: 301 FGLCGDVHVRLRQRIILYELKVELEETVVRRQAAVRTLGQQARVWLVRVLLNLLVVALLG 360
Query: 355 AAFYGVYWATGCTVELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLIAPLEGY 414
AAFYGVYWATGCTVELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLIAPLEGY
Sbjct: 361 AAFYGVYWATGCTVELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLIAPLEGY 420
Query: 415 TRSRQIVFILLRTVFLRLASLVVLLFSLWNQITCGGDSEAEDCKTCGYNYKQLPCWETVL 474
TRSRQIVFILLRTVFLRLASLVVLLFSLWNQITCGGDSEAEDCKTCGYNYKQLPCWETVL
Sbjct: 421 TRSRQIVFILLRTVFLRLASLVVLLFSLWNQITCGGDSEAEDCKTCGYNYKQLPCWETVL 480
Query: 475 GQEMYKLLLFDLLTVLAVALLIQFPRKLLCGLCPGALGRLAGTQEFQVPDEVLGLIYAQT 534
GQEMYKLLLFDLLTVLAVALLIQFPRKLLCGLCPGALGRLAGTQEFQVPDEVLGLIYAQT
Sbjct: 481 GQEMYKLLLFDLLTVLAVALLIQFPRKLLCGLCPGALGRLAGTQEFQVPDEVLGLIYAQT 540
Query: 535 VVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANFFFPLVLLLGLA 594
VVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANFFFPLVLLLGLA
Sbjct: 541 VVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANFFFPLVLLLGLA 600
Query: 595 ISSVPLLYSIFLIPPSKLCGPFRGQSSIWAQIPESISSLPETTQNFLFFLGTQAFAVPLL 654
ISSVPLLYSIFLIPPSKLCGPFRGQSSIWAQIPESISSLPETTQNFLFFLGTQAFAVPLL
Sbjct: 601 ISSVPLLYSIFLIPPSKLCGPFRGQSSIWAQIPESISSLPETTQNFLFFLGTQAFAVPLL 660
Query: 655 LISSILMAYTVALANSYGRLISELKRQRQTEAQNKVFLARRAVALTSTKPAL 706
LISSILMAYTVALANSYGRLISELKRQRQTEAQNKVFLARRAVALTSTKPAL
Sbjct: 661 LISSILMAYTVALANSYGRLISELKRQRQTEAQNKVFLARRAVALTSTKPAL 712
>gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens]
Length = 723
Score = 434 bits (1117), Expect = e-121
Identities = 257/688 (37%), Positives = 392/688 (56%), Gaps = 40/688 (5%)
Query: 34 LNELPSAATLRYRDPGVLPWGALEEEEEDGGRSRKAFTEVTQTELQD-------PHPSRE 86
L ELPS ++ R V ++ G K T+ ++L+D H R
Sbjct: 40 LQELPSYRSIARRRTTV------HSRDKQSGTLLKP-TDSYSSQLEDRIAENLSSHSLRN 92
Query: 87 LPWPMQARRAHRQRNASRDQVVYGSGTKTDRWARLLRRS----KEKTKEGLRSLQPWAWT 142
+ +R R R+ Q+ Y S + D+W R +S EK +E L+ W
Sbjct: 93 YALNISEKR--RLRDIQETQMKYLS--EWDQWKRYSSKSWKRFLEKAREMTTHLELWRED 148
Query: 143 LKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTLLPTWL------GGAPPGPPGPD 196
++ I G+FG G +SYFS LRFL+LLN++ +++ + LLP L + P D
Sbjct: 149 IRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKD 208
Query: 197 ISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPPRP--------RLAVTY 248
+ C Y S GL+ F + + +LLSG G+LE + LFYG Y L + Y
Sbjct: 209 MDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEETSLFYGHYTIDGVKFQNFTYDLPLAY 268
Query: 249 LCWAFAVGLICLLLILHRSVSGLKQTLLAESEALTSYSHRVFSAWDFGLCGDVHVRLRQR 308
L A + LL I+ RSV G K L+ E SY +++F+ WDF + L+
Sbjct: 269 LLSTIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHS 328
Query: 309 IILYELKVELEETVVRRQAAVRTLGQQARVWLVRVLLNLLVVALLGAAFYGVYWATGCTV 368
+ YEL+ +LEE +R++ A RT + R++ +R+ LN +V+A+LGA FY +Y AT +
Sbjct: 329 SLRYELRADLEEERMRQKIAERTSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQ 388
Query: 369 ELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLIAPLEGYTRSRQIVFILLRTV 428
E + + + + L + YLPSI I NF+ P +F I E Y+ +I +LR V
Sbjct: 389 EHMKKEIDKMVFGENLFILYLPSIVITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCV 448
Query: 429 FLRLASLVVLLFSLWNQITCGGDSEAEDCKTCGYNYKQLPCWETVLGQEMYKLLLFDLLT 488
F+RLA++ VL+F+L ++IT D + C CGYN K PCWET +GQEMYKL++FD +
Sbjct: 449 FMRLATICVLVFTLGSKITSCDD---DTCDLCGYNQKLYPCWETQVGQEMYKLMIFDFII 505
Query: 489 VLAVALLIQFPRKLLCGLCPGA-LGRLAGTQEFQVPDEVLGLIYAQTVVWVGSFFCPLLP 547
+LAV L + FPRKLL C L + G QEF +PD VLG++Y QT+ W+G+FF PLLP
Sbjct: 506 ILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLP 565
Query: 548 LLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANFFFPLVLLLGLAISSVPLLYSIFLI 607
+ T+KF+++FY+K+ +L TC P+ R FRAS +NFFF LVLL+GL ++ +PL SI I
Sbjct: 566 AIATLKFIIIFYVKEWSLLYTCRPSPRPFRASNSNFFFLLVLLIGLCLAIIPLTISISRI 625
Query: 608 PPSKLCGPFRGQSSIWAQIPESISSLPETTQNFLFFLGTQAFAVPLLLISSILMAYTVAL 667
P SK CGPF ++ W IP+++S+ P + Q+F+ + ++AFAVP +I ++M Y +AL
Sbjct: 626 PSSKACGPFTNFNTTWEVIPKTVSTFPSSLQSFIHGVTSEAFAVPFFMIICLIMFYFIAL 685
Query: 668 ANSYGRLISELKRQRQTEAQNKVFLARR 695
A ++ R++ +L+ Q E+++K +L ++
Sbjct: 686 AGAHKRVVIQLREQLSLESRDKCYLIQK 713
>gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens]
Length = 613
Score = 432 bits (1112), Expect = e-121
Identities = 237/599 (39%), Positives = 359/599 (59%), Gaps = 22/599 (3%)
Query: 116 DRWARLLRRS----KEKTKEGLRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLA 171
D+W R +S EK +E L+ W ++ I G+FG G +SYFS LRFL+LLN++
Sbjct: 8 DQWKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVI 67
Query: 172 SVLMACMTLLPTWL------GGAPPGPPGPDISSPCGSYNPHSQGLVTFATQLFNLLSGE 225
+++ + LLP L + P D+ C Y S GL+ F + + +LLSG
Sbjct: 68 FLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGT 127
Query: 226 GYLEWSPLFYGFYPPRP--------RLAVTYLCWAFAVGLICLLLILHRSVSGLKQTLLA 277
G+LE + LFYG Y L + YL A + LL I+ RSV G K L+
Sbjct: 128 GFLEETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLIR 187
Query: 278 ESEALTSYSHRVFSAWDFGLCGDVHVRLRQRIILYELKVELEETVVRRQAAVRTLGQQAR 337
E SY +++F+ WDF + L+ + YEL+ +LEE +R++ A RT + R
Sbjct: 188 SEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAERTSEETIR 247
Query: 338 VWLVRVLLNLLVVALLGAAFYGVYWATGCTVELQEMPLVQELPLLKLGVNYLPSIFIAGV 397
++ +R+ LN +V+A+LGA FY +Y AT + E + + + + L + YLPSI I
Sbjct: 248 IYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMKKEIDKMVFGENLFILYLPSIVITLA 307
Query: 398 NFVLPPVFKLIAPLEGYTRSRQIVFILLRTVFLRLASLVVLLFSLWNQITCGGDSEAEDC 457
NF+ P +F I E Y+ +I +LR VF+RLA++ VL+F+L ++IT D + C
Sbjct: 308 NFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITSCDD---DTC 364
Query: 458 KTCGYNYKQLPCWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLCGLCPGA-LGRLAG 516
CGYN K PCWET +GQEMYKL++FD + +LAV L + FPRKLL C L + G
Sbjct: 365 DLCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWG 424
Query: 517 TQEFQVPDEVLGLIYAQTVVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAARTF 576
QEF +PD VLG++Y QT+ W+G+FF PLLP + T+KF+++FY+K+ +L TC P+ R F
Sbjct: 425 QQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPF 484
Query: 577 RASAANFFFPLVLLLGLAISSVPLLYSIFLIPPSKLCGPFRGQSSIWAQIPESISSLPET 636
RAS +NFFF LVLL+GL ++ +PL SI IP SK CGPF ++ W IP+++S+ P +
Sbjct: 485 RASNSNFFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVSTFPSS 544
Query: 637 TQNFLFFLGTQAFAVPLLLISSILMAYTVALANSYGRLISELKRQRQTEAQNKVFLARR 695
Q+F+ + ++AFAVP +I ++M Y +ALA ++ R++ +L+ Q E+++K +L ++
Sbjct: 545 LQSFIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLESRDKCYLIQK 603
>gi|23943900 transmembrane channel-like 8 [Homo sapiens]
Length = 726
Score = 332 bits (850), Expect = 9e-91
Identities = 225/626 (35%), Positives = 322/626 (51%), Gaps = 40/626 (6%)
Query: 83 PSRELPWPMQARRAHRQRNASRDQVVYGSGTKTDRWAR-------LLRRSKEKTKEGLRS 135
P R LP+ M +R Q +G +T RW R + RR +E + R
Sbjct: 35 PVRGLPYAMMDKRLIWQLREP-------AGVQTLRWQRWQRRRQTVERRLREAAQRLARG 87
Query: 136 LQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTLLP-TWLGGAPPGPPG 194
L W L IGG FG G SYF+ LRFLLLLN+L+ +L A LLP WL PGP
Sbjct: 88 LGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWLRPPDPGPT- 146
Query: 195 PDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPPRPR------LAVTY 248
+++ C G++ F QL+++L+G + + LFYG Y P + + Y
Sbjct: 147 LNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFTN-TYLFYGAYRVGPESSSVYSIRLAY 205
Query: 249 LCWAFAVGLICLLLILHRSVSGLKQTLLAESEALTSYSHRVFSAWDFGLCGDVHVRLRQR 308
L A L+C L R V GL Q L S +VFS+WDF + +++
Sbjct: 206 LLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATIKKH 265
Query: 309 IILYELKVELEE----TVVRRQAAVRTLGQQARVWLVRVLLNLLVVALLGAAFYGVYWAT 364
I E KVELEE ++++Q +T + V VL LLVV + A ++WAT
Sbjct: 266 EISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLVVGAISA----IFWAT 321
Query: 365 GCTVELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLIAPLEGYTRSRQIVFIL 424
+ + +E L L + YLP IA VNF+ P +F + LE Y + ++ L
Sbjct: 322 KYSQDNKEESLF-------LLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLTL 374
Query: 425 LRTVFLRLASLVVLLFSLWNQITCGGDSEAEDCKTCGYNYKQLPCWETVLGQEMYKLLLF 484
+ V L+LASL + SL I C G ++ C++ GYN CWE +G+E+YKL +F
Sbjct: 375 IWCVVLKLASLGMFSVSLGQTILCIGRDKSS-CESYGYNVCDYQCWENSVGEELYKLSIF 433
Query: 485 DLLTVLAVALLIQFPRKLLCGLCPGALGRLAGTQEFQVPDEVLGLIYAQTVVWVGSFFCP 544
+ L +A A L+ PR+LL G +EF VP VL ++ QTV W+G F+CP
Sbjct: 434 NFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVTWMGLFYCP 493
Query: 545 LLPLLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANFFFPLVLLLGLAISSVPLLYSI 604
LLPLLN+V L FY+KK TL ++R FRAS++ FFF LVLLLGL +++VPL Y +
Sbjct: 494 LLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLLGLLLAAVPLGYVV 553
Query: 605 FLIPPSKLCGPFRGQSSIWAQIPESIS-SLPETTQNFLFFLGTQAFAVPLLLISSILMAY 663
I S CG F S+ W +PE ++ LP Q L +LG+ AF+ PLL++ S+++
Sbjct: 554 SSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLIMLSLVLTV 613
Query: 664 TVALANSYGRLISELKRQRQTEAQNK 689
V+ + R I L++Q + Q K
Sbjct: 614 CVSQTQANARAIHRLRKQLVWQVQEK 639
>gi|157426860 transmembrane channel-like 5 isoform a [Homo sapiens]
Length = 1006
Score = 182 bits (461), Expect = 1e-45
Identities = 158/601 (26%), Positives = 267/601 (44%), Gaps = 74/601 (12%)
Query: 119 ARLLRRSKEKTKEGLRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACM 178
+R RRSK E L S+ W TLK IGG+FG SYF+ LR+LL N+ + +L
Sbjct: 411 SRAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSF 470
Query: 179 TLLPTWLGGAPPGPPGPDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFY 238
++P + + + F F +G GY + ++YGFY
Sbjct: 471 IIIP--------------------QFTVAKKNTLQFTGLEF--FTGVGYFRDTVMYYGFY 508
Query: 239 P----PRPRLAVTY---LCWAFAVGLI---CLLLILHRSVSGLKQTLLAESEALTSYSHR 288
+Y L + F +G C +L + + +
Sbjct: 509 TNSTIQHGNSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKL 568
Query: 289 VFSAWDFGLCGDVHVRLRQRIILYELKVELEETVVRRQAAVRTLGQQARVWLVRVLLNLL 348
+F WDF + + V+L+Q+ + E++ L E +R++ + T Q + ++ ++
Sbjct: 569 IF-CWDFTVTHEKAVKLKQKNLSTEIRENLSE--LRQENSKLTFNQLLTRFSAYMVAWVV 625
Query: 349 VVALLGAAFYGVYWATGCTVELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLI 408
+ A VY+ +E + LL LP + ++ +N +P ++ +
Sbjct: 626 STGVAIACCAAVYYLAEYNLEFLKTHSNPGAVLL------LPFV-VSCINLAVPCIYSMF 678
Query: 409 APLEGYTRSRQIVFILL-RTVFLRLASLVVLLFSLWNQITCGGDSEAEDCKTCGYNYKQL 467
+E Y R V++LL R +FL+++ + +L + N + G+
Sbjct: 679 RLVERYEMPRHEVYVLLIRNIFLKISIIGILCYYWLNTVALSGEE--------------- 723
Query: 468 PCWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLCGLCPGALGRLAGTQEFQVPDEVL 527
CWET++GQ++Y+LLL D + L + L +F R+++ G+ L G QEF + VL
Sbjct: 724 -CWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRII-GM---QLITSLGLQEFDIARNVL 778
Query: 528 GLIYAQTVVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANFFFPL 587
LIYAQT+VW+G FFCPLLP + + ++FY K ++L P ++ +RAS FF +
Sbjct: 779 ELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFF-I 837
Query: 588 VLLLGLAISSV--PLLYSIFLIPPSKLCGPFRGQSSIWAQIPESISSLPETTQNFLF--- 642
LL + + V L +I+ + PS CGPFRG I I +L T +L+
Sbjct: 838 FLLFFPSFTGVLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSWIDTL-STRPGYLWVVW 896
Query: 643 ----FLGTQAFAVPLLLISSILMAYTVALANSYGRLISELKRQRQTEAQNKVFLARRAVA 698
+G+ F L LI I+ + +I L Q E ++K+FL + +
Sbjct: 897 IYRNLIGSVHFFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIINEGKDKMFLIEKLIK 956
Query: 699 L 699
L
Sbjct: 957 L 957
>gi|31377679 transmembrane channel-like 5 isoform c [Homo sapiens]
Length = 760
Score = 182 bits (461), Expect = 1e-45
Identities = 158/601 (26%), Positives = 267/601 (44%), Gaps = 74/601 (12%)
Query: 119 ARLLRRSKEKTKEGLRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACM 178
+R RRSK E L S+ W TLK IGG+FG SYF+ LR+LL N+ + +L
Sbjct: 165 SRAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSF 224
Query: 179 TLLPTWLGGAPPGPPGPDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFY 238
++P + + + F F +G GY + ++YGFY
Sbjct: 225 IIIP--------------------QFTVAKKNTLQFTGLEF--FTGVGYFRDTVMYYGFY 262
Query: 239 P----PRPRLAVTY---LCWAFAVGLI---CLLLILHRSVSGLKQTLLAESEALTSYSHR 288
+Y L + F +G C +L + + +
Sbjct: 263 TNSTIQHGNSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKL 322
Query: 289 VFSAWDFGLCGDVHVRLRQRIILYELKVELEETVVRRQAAVRTLGQQARVWLVRVLLNLL 348
+F WDF + + V+L+Q+ + E++ L E +R++ + T Q + ++ ++
Sbjct: 323 IF-CWDFTVTHEKAVKLKQKNLSTEIRENLSE--LRQENSKLTFNQLLTRFSAYMVAWVV 379
Query: 349 VVALLGAAFYGVYWATGCTVELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLI 408
+ A VY+ +E + LL LP + ++ +N +P ++ +
Sbjct: 380 STGVAIACCAAVYYLAEYNLEFLKTHSNPGAVLL------LPFV-VSCINLAVPCIYSMF 432
Query: 409 APLEGYTRSRQIVFILL-RTVFLRLASLVVLLFSLWNQITCGGDSEAEDCKTCGYNYKQL 467
+E Y R V++LL R +FL+++ + +L + N + G+
Sbjct: 433 RLVERYEMPRHEVYVLLIRNIFLKISIIGILCYYWLNTVALSGEE--------------- 477
Query: 468 PCWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLCGLCPGALGRLAGTQEFQVPDEVL 527
CWET++GQ++Y+LLL D + L + L +F R+++ G+ L G QEF + VL
Sbjct: 478 -CWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRII-GM---QLITSLGLQEFDIARNVL 532
Query: 528 GLIYAQTVVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANFFFPL 587
LIYAQT+VW+G FFCPLLP + + ++FY K ++L P ++ +RAS FF +
Sbjct: 533 ELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFF-I 591
Query: 588 VLLLGLAISSV--PLLYSIFLIPPSKLCGPFRGQSSIWAQIPESISSLPETTQNFLF--- 642
LL + + V L +I+ + PS CGPFRG I I +L T +L+
Sbjct: 592 FLLFFPSFTGVLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSWIDTL-STRPGYLWVVW 650
Query: 643 ----FLGTQAFAVPLLLISSILMAYTVALANSYGRLISELKRQRQTEAQNKVFLARRAVA 698
+G+ F L LI I+ + +I L Q E ++K+FL + +
Sbjct: 651 IYRNLIGSVHFFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIINEGKDKMFLIEKLIK 710
Query: 699 L 699
L
Sbjct: 711 L 711
>gi|21071070 transmembrane channel-like 1 [Homo sapiens]
Length = 760
Score = 176 bits (447), Expect = 5e-44
Identities = 169/671 (25%), Positives = 290/671 (43%), Gaps = 85/671 (12%)
Query: 88 PWPMQAR---RAHRQRNASRDQVVYGSGTKTDRWARLLRRSKEKTKEGLRSLQ------- 137
PW M+ + ++ S ++ G G K RW +K + LR +
Sbjct: 110 PWKMEKKIEVLKEAKKFVSENEGALGKG-KGKRWFAFKMMMAKKWAKFLRDFENFKAACV 168
Query: 138 PWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTLLPTWLGGAPPGPPGPDI 197
PW +K I QFG+ SYF LR++ +N++ +L + +LP +L G P G
Sbjct: 169 PWENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYG------ 222
Query: 198 SSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPPRP-------RLAVTYLC 250
S P + + L++ G ++S LFYG+Y + RL ++Y
Sbjct: 223 SLPRKTVPRAEEASAANFGVLYDF---NGLAQYSVLFYGYYDNKRTIGWMNFRLPLSY-- 277
Query: 251 WAFAVGLICL----LLILHRSVSGLKQTLLAESEALTSYSHRVFSAWDFGLCGDVHVRLR 306
F VG++C+ L++L + + ++S +VF++WD+ L G+
Sbjct: 278 --FLVGIMCIGYSFLVVLKAMTKNIGDDGGGDDNTF-NFSWKVFTSWDY-LIGNPETADN 333
Query: 307 QRIILYELKVELEETVVRRQAAVRTLGQQARVWLVRVLLNLLVVALLGAAFYGVYWATGC 366
+ + + +E + +AA + + +R L N V LG + Y ++WA
Sbjct: 334 K---FNSITMNFKEAITEEKAA-QVEENVHLIRFLRFLANFFVFLTLGGSGYLIFWAVKR 389
Query: 367 TVELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLIAPLEGYTRSRQIVFILLR 426
+ E + Q+ L ++ ++ + P +F L A LE Y + ++L R
Sbjct: 390 SQEFAQ----QDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGR 445
Query: 427 TVFLRLASLVVLLFSLWNQITCGGDSE-----------AEDCKTCGYNYKQL-------- 467
L L +L V + +L ++I + E A K ++ +
Sbjct: 446 IFALLLGNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFFV 505
Query: 468 --------PCWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLCGLCPGA------LGR 513
PCWET++GQE +L + D+LT L+ F R C G
Sbjct: 506 HPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGY 565
Query: 514 LAGTQEFQVPDEVLGLIYAQTVVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAA 573
+ T EF + VL LI+ Q ++W+GSFF P LP +N ++ Y + + P A
Sbjct: 566 PSYT-EFDISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEA 624
Query: 574 RTFRASAANFFFPLVLLLGLAISSVPLLYSIFLIPPSKLCGPFRGQSSIWAQIPESIS-S 632
R F+AS +N F+ +LLL L +S++P+LY I +PPS CGPF G++ ++ I E++
Sbjct: 625 RVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHD 684
Query: 633 LPETTQNFLFFLGTQAFAVPLLLISSILMAYTVALANSYGRLISELKRQRQTEA-----Q 687
P L L + ++L+ + + Y A A +LK++ + +A +
Sbjct: 685 FPSWMAKILRQLSNPGLVIAVILVMVLAIYYLNATAKGQKAANLDLKKKMKMQALENKMR 744
Query: 688 NKVFLARRAVA 698
NK A RA A
Sbjct: 745 NKKMAAARAAA 755
>gi|94536852 transmembrane cochlear-expressed protein 2 [Homo
sapiens]
Length = 906
Score = 172 bits (436), Expect = 1e-42
Identities = 165/647 (25%), Positives = 287/647 (44%), Gaps = 71/647 (10%)
Query: 85 RELPWPMQARRAHRQRNASRDQVVY------GSGTKTDRWARLLRRSKEKTKEGLRSLQ- 137
R PWPM A++ R A Y G G + + L+ + K K + +
Sbjct: 171 RSKPWPM-AKKLTELREAQEFVEKYEGALGKGKGKQLYAYKMLMAKKWVKFKRDFDNFKT 229
Query: 138 ---PWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTLLPTWLGGAPPGPPG 194
PW +K I FG+ SYF LR++ +N++ L+ + ++P L G P G
Sbjct: 230 QCIPWEMKIKDIESHFGSSVASYFIFLRWMYGVNLVLFGLIFGLVIIPEVLMGMPYGSI- 288
Query: 195 PDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPP-------RPRLAVT 247
P + P + + F+ L EGY+++S LFYG+Y R RL +
Sbjct: 289 PRKTVP----RAEEEKAMDFSV----LWDFEGYIKYSALFYGYYNNQRTIGWLRYRLPMA 340
Query: 248 YLCWAFAVGLICLLLILHRSVSGLKQTLLAESEALT-SYSHRVFSAWDFGLCGDVHVRLR 306
Y +V L++++ RS++ Q E E+ ++S ++F++WD+ L G+
Sbjct: 341 YFMVGVSVFGYSLIIVI-RSMASNTQGSTGEGESDNFTFSFKMFTSWDY-LIGNSETADN 398
Query: 307 QRIILYELKVELEETVVRRQAAVRTLGQQARVWLVRVLLNLLVVALLGAAFYGVYWATGC 366
+ + +E++V Q + + +L RVL N L++ L + Y +Y+
Sbjct: 399 KYA---SITTSFKESIVDEQESNKEENIHLTRFL-RVLANFLIICCLCGSGYLIYFVVKR 454
Query: 367 TVELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLIAPLEGYTRSRQIVFILLR 426
+ + +M V ++ I ++ + PP+F+ IA LE Y + + L R
Sbjct: 455 SQQFSKMQNVSWYERNEV------EIVMSLLGMFCPPLFETIAALENYHPRTGLKWQLGR 508
Query: 427 TVFLRLASLVVLLFSLWNQITCGGDSEAEDCKTCG----YNY-------KQLP------- 468
L L +L L +L + + +E E K +NY + +P
Sbjct: 509 IFALFLGNLYTFLLALMDDVHLKLANE-ETIKNITHWTLFNYYNSSGWNESVPRPPLHPA 567
Query: 469 ------CWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLCGL-----CPGALGRLAGT 517
CWET +G E +L + D+L LL F R C
Sbjct: 568 DVPRGSCWETAVGIEFMRLTVSDMLVTYITILLGDFLRACFVRFMNYCWCWDLEAGFPSY 627
Query: 518 QEFQVPDEVLGLIYAQTVVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAARTFR 577
EF + VLGLI+ Q ++W+GSF+ P L +N ++ L Y + + S+ P R F+
Sbjct: 628 AEFDISGNVLGLIFNQGMIWMGSFYAPGLVGINVLRLLTSMYFQCWAVMSSNVPHERVFK 687
Query: 578 ASAANFFFPLVLLLGLAISSVPLLYSIFLIPPSKLCGPFRGQSSIWAQIPESI-SSLPET 636
AS +N F+ +LLL L +S +P+ Y+I +PPS CGPF G++ ++ + E+I + P
Sbjct: 688 ASRSNNFYMGLLLLVLFLSLLPVAYTIMSLPPSFDCGPFSGKNRMYDVLQETIENDFPTF 747
Query: 637 TQNFLFFLGTQAFAVPLLLISSILMAYTVALANSYGRLISELKRQRQ 683
FL +P +L+ + + Y +++ S R ++L+++ Q
Sbjct: 748 LGKIFAFLANPGLIIPAILLMFLAIYYLNSVSKSLSRANAQLRKKIQ 794
>gi|157426862 transmembrane channel-like 5 isoform b [Homo sapiens]
Length = 948
Score = 164 bits (414), Expect = 3e-40
Identities = 127/482 (26%), Positives = 218/482 (45%), Gaps = 63/482 (13%)
Query: 119 ARLLRRSKEKTKEGLRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACM 178
+R RRSK E L S+ W TLK IGG+FG SYF+ LR+LL N+ + +L
Sbjct: 411 SRAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSF 470
Query: 179 TLLPTWLGGAPPGPPGPDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFY 238
++P + + + F F +G GY + ++YGFY
Sbjct: 471 IIIP--------------------QFTVAKKNTLQFTGLEF--FTGVGYFRDTVMYYGFY 508
Query: 239 P----PRPRLAVTY---LCWAFAVGLI---CLLLILHRSVSGLKQTLLAESEALTSYSHR 288
+Y L + F +G C +L + + +
Sbjct: 509 TNSTIQHGNSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPHIYSGGITKL 568
Query: 289 VFSAWDFGLCGDVHVRLRQRIILYELKVELEETVVRRQAAVRTLGQQARVWLVRVLLNLL 348
+F WDF + + V+L+Q+ + E++ L E +R++ + T Q + ++ ++
Sbjct: 569 IF-CWDFTVTHEKAVKLKQKNLSTEIRENLSE--LRQENSKLTFNQLLTRFSAYMVAWVV 625
Query: 349 VVALLGAAFYGVYWATGCTVELQEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLI 408
+ A VY+ +E + LL LP + ++ +N +P ++ +
Sbjct: 626 STGVAIACCAAVYYLAEYNLEFLKTHSNPGAVLL------LPFV-VSCINLAVPCIYSMF 678
Query: 409 APLEGYTRSRQIVFILL-RTVFLRLASLVVLLFSLWNQITCGGDSEAEDCKTCGYNYKQL 467
+E Y R V++LL R +FL+++ + +L + N + G+
Sbjct: 679 RLVERYEMPRHEVYVLLIRNIFLKISIIGILCYYWLNTVALSGEE--------------- 723
Query: 468 PCWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLCGLCPGALGRLAGTQEFQVPDEVL 527
CWET++GQ++Y+LLL D + L + L +F R+++ G+ L G QEF + VL
Sbjct: 724 -CWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRII-GM---QLITSLGLQEFDIARNVL 778
Query: 528 GLIYAQTVVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANFFFPL 587
LIYAQT+VW+G FFCPLLP + + ++FY K ++L P ++ +RAS FF
Sbjct: 779 ELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIF 838
Query: 588 VL 589
+L
Sbjct: 839 LL 840
>gi|187608784 transmembrane channel-like 6 [Homo sapiens]
Length = 805
Score = 149 bits (376), Expect = 9e-36
Identities = 169/623 (27%), Positives = 264/623 (42%), Gaps = 120/623 (19%)
Query: 133 LRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTLLPTWLGGAPPGP 192
L++L PW + LKRIGGQFG+ SYF L+ LL N L +L+ + P PP
Sbjct: 224 LQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQV--AFPPAL 281
Query: 193 PGPDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPPR----------- 241
PGP P GL LL+G G + ++YG Y
Sbjct: 282 PGPA---------PVCTGL--------ELLTGAGCFTHTVMYYGHYSNATLNQPCGSPLD 324
Query: 242 -----PRLA-VTY---LCWAFAVG----LICLLLILHRSVSGLKQTLLAESEALTSYSHR 288
PR+ + Y L + VG + C+ L+ + S + + + + + +
Sbjct: 325 GSQCTPRVGGLPYNMPLAYLSTVGVSFFITCITLVYSMAHSFGESYRVGSTSGIHAIT-- 382
Query: 289 VFSAWDFGLCGDVHVRLRQRIILYELKVELEETVVR----------RQAAVRTLGQQARV 338
VF +WD+ + RL+Q I LK L E +R RQAAV L V
Sbjct: 383 VFCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQAAVLGL-----V 437
Query: 339 WLVRVLLNL---LVVALLGAAFYGVYWATGCTVELQEMPLVQELPLLKLGVNYLPSIFIA 395
WL+ + L + V + A G L +PLV + LL LG YL
Sbjct: 438 WLLCLGTALGCAVAVHVFSEFMIQSPEAAGQEAVLLVLPLV--VGLLNLGAPYL------ 489
Query: 396 GVNFVLPPVFKLIAPLEGYTRSRQIVFILL-RTVFLRLASLVVLLFSLWNQITCGGDSEA 454
+++A LE + V++ + R + L+LA L L + W G
Sbjct: 490 ---------CRVLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYH-WLGRRVG----- 534
Query: 455 EDCKTCGYNYKQLPCWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLCGLCPGALGRL 514
Q CWE +GQE+Y+ L+ D + +L L +L+ + +
Sbjct: 535 ---------VLQGQCWEDFVGQELYRFLVMDFVLMLLDTLF----GELVWRIISEKKLKR 581
Query: 515 AGTQEFQVPDEVLGLIYAQTVVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAAR 574
EF + VL LIY QT+ W+G F PLLP + +K LL+FY+KK +L + C R
Sbjct: 582 RRKPEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPRR 641
Query: 575 TFRAS-AANFFFPLVLLLGLAISSVPLLYSIFLIPPSKLCGPFRGQSS------IWAQIP 627
+ AS + F L+ ++V L Y+++ + PS CGPFR + +W +
Sbjct: 642 PWLASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHL 701
Query: 628 ES----ISSLPETTQNFLFFLGTQAFAVPLLLISSILMA---YTVALANSYGRLISELKR 680
E+ +S LP + +L F V L+S++L+A + + ++I LK
Sbjct: 702 EAAGPRVSWLPWVHR----YLMENTFFV--FLVSALLLAVIYLNIQVVRGQRKVICLLKE 755
Query: 681 QRQTEAQNKVFLARRAVALTSTK 703
Q E ++K+FL + ++ K
Sbjct: 756 QISNEGEDKIFLINKLHSIYERK 778
>gi|187608791 transmembrane channel-like 6 [Homo sapiens]
Length = 805
Score = 149 bits (376), Expect = 9e-36
Identities = 169/623 (27%), Positives = 264/623 (42%), Gaps = 120/623 (19%)
Query: 133 LRSLQPWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTLLPTWLGGAPPGP 192
L++L PW + LKRIGGQFG+ SYF L+ LL N L +L+ + P PP
Sbjct: 224 LQALMPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQV--AFPPAL 281
Query: 193 PGPDISSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPPR----------- 241
PGP P GL LL+G G + ++YG Y
Sbjct: 282 PGPA---------PVCTGL--------ELLTGAGCFTHTVMYYGHYSNATLNQPCGSPLD 324
Query: 242 -----PRLA-VTY---LCWAFAVG----LICLLLILHRSVSGLKQTLLAESEALTSYSHR 288
PR+ + Y L + VG + C+ L+ + S + + + + + +
Sbjct: 325 GSQCTPRVGGLPYNMPLAYLSTVGVSFFITCITLVYSMAHSFGESYRVGSTSGIHAIT-- 382
Query: 289 VFSAWDFGLCGDVHVRLRQRIILYELKVELEETVVR----------RQAAVRTLGQQARV 338
VF +WD+ + RL+Q I LK L E +R RQAAV L V
Sbjct: 383 VFCSWDYKVTQKRASRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQAAVLGL-----V 437
Query: 339 WLVRVLLNL---LVVALLGAAFYGVYWATGCTVELQEMPLVQELPLLKLGVNYLPSIFIA 395
WL+ + L + V + A G L +PLV + LL LG YL
Sbjct: 438 WLLCLGTALGCAVAVHVFSEFMIQSPEAAGQEAVLLVLPLV--VGLLNLGAPYL------ 489
Query: 396 GVNFVLPPVFKLIAPLEGYTRSRQIVFILL-RTVFLRLASLVVLLFSLWNQITCGGDSEA 454
+++A LE + V++ + R + L+LA L L + W G
Sbjct: 490 ---------CRVLAALEPHDSPVLEVYVAICRNLILKLAILGTLCYH-WLGRRVG----- 534
Query: 455 EDCKTCGYNYKQLPCWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLCGLCPGALGRL 514
Q CWE +GQE+Y+ L+ D + +L L +L+ + +
Sbjct: 535 ---------VLQGQCWEDFVGQELYRFLVMDFVLMLLDTLF----GELVWRIISEKKLKR 581
Query: 515 AGTQEFQVPDEVLGLIYAQTVVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAAR 574
EF + VL LIY QT+ W+G F PLLP + +K LL+FY+KK +L + C R
Sbjct: 582 RRKPEFDIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPRR 641
Query: 575 TFRAS-AANFFFPLVLLLGLAISSVPLLYSIFLIPPSKLCGPFRGQSS------IWAQIP 627
+ AS + F L+ ++V L Y+++ + PS CGPFR + +W +
Sbjct: 642 PWLASHMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHL 701
Query: 628 ES----ISSLPETTQNFLFFLGTQAFAVPLLLISSILMA---YTVALANSYGRLISELKR 680
E+ +S LP + +L F V L+S++L+A + + ++I LK
Sbjct: 702 EAAGPRVSWLPWVHR----YLMENTFFV--FLVSALLLAVIYLNIQVVRGQRKVICLLKE 755
Query: 681 QRQTEAQNKVFLARRAVALTSTK 703
Q E ++K+FL + ++ K
Sbjct: 756 QISNEGEDKIFLINKLHSIYERK 778
>gi|122937502 transmembrane channel-like 3 [Homo sapiens]
Length = 1100
Score = 122 bits (305), Expect = 1e-27
Identities = 77/242 (31%), Positives = 125/242 (51%), Gaps = 7/242 (2%)
Query: 469 CWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLCGL-----CPGALGRLAGTQEFQVP 523
CWET +GQEM KL + D+L +A LLI F R L C + EF++
Sbjct: 499 CWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSDYWCWDLESKFPEYGEFKIA 558
Query: 524 DEVLGLIYAQTVVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANF 583
+ VL L+Y Q ++W+G+FF P LP N +K + L YL+ + + P + FRAS +N
Sbjct: 559 ENVLHLVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVLTCNVPHQQVFRASRSNN 618
Query: 584 FFPLVLLLGLAISSVPLLYSIFLIPPSKLCGPFRGQSSIWAQIPESI-SSLPETTQNFLF 642
F+ +LL L + +P +++I PS CGPF GQ I+ + E+I P + +
Sbjct: 619 FYLAMLLFMLFLCMLPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGSVVG 678
Query: 643 FLGTQAFAVPLLLISSILMAYTVALANSYGRLISELKRQRQ-TEAQNKVFLARRAVALTS 701
+ + +P +L+ +L+ Y ++A S +LK Q Q +++K +A+ A
Sbjct: 679 HISSPVVILPAVLLLFMLIYYLQSIARSLKLSNHQLKMQIQNARSEDKKKVAQMVEARIQ 738
Query: 702 TK 703
T+
Sbjct: 739 TQ 740
Score = 103 bits (257), Expect = 5e-22
Identities = 81/316 (25%), Positives = 142/316 (44%), Gaps = 26/316 (8%)
Query: 138 PWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTLLPTWLGGAPPGPPGPDI 197
PW +K+I FG+G SYF LR+L +N++ +++ ++P + G P G
Sbjct: 122 PWEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVIPELIAGQPFG------ 175
Query: 198 SSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPPRP-------RLAVTYLC 250
S P Q V+ A L + S GYL++S LFYG+Y RL + Y
Sbjct: 176 -STARKTIPKEQ--VSSAQDLDTVWSLGGYLQYSVLFYGYYGRERKIGRAGYRLPLAYFL 232
Query: 251 WAFAVGLICLLLILHRSVSGLKQTLLAESEALTSYSHRVFSAWDFGLCGDVHVRLRQRII 310
AV +++L + + +L + S ++ RVF AWD+ + + I
Sbjct: 233 VGMAVFAYSFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPEAAESKTAAI 292
Query: 311 LYELKVELEETVVRRQAAVRTLGQQARVWLVRVLLNLLVVALLGAAFYGVYWATGCTVEL 370
+ ++ E ++ Q ++ + L R++ N+LV+ L + Y +Y+ + +L
Sbjct: 293 VNSIR----EAILEEQEKKKSKNLAVTICL-RIIANILVLLSLAGSIYLIYFVVDRSQKL 347
Query: 371 QEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLIAPLEGYTRSRQIVFILLRTVFL 430
+ Q L L S+ ++ V + P F LIA LE Y + F L R + L
Sbjct: 348 E-----QSKKELTLWEKNEVSVVVSLVTMIAPSAFDLIAALEMYHPRTTLRFQLARVLVL 402
Query: 431 RLASLVVLLFSLWNQI 446
L +L L+ +L +++
Sbjct: 403 YLGNLYSLIIALLDKV 418
>gi|122937243 dual specificity phosphatase 27 [Homo sapiens]
Length = 1158
Score = 36.6 bits (83), Expect = 0.082
Identities = 34/126 (26%), Positives = 50/126 (39%), Gaps = 15/126 (11%)
Query: 17 GWLAPREARGGPSLSS-----VLNELPSAATLRYRDPGVLPWGALEEEEEDG------GR 65
GW + +GG L ++ E S RY+ G WG EE+EE+ GR
Sbjct: 371 GWRSASSGQGGEELEDEDVERIIQEWQSRNE-RYQAEGYRRWGREEEKEEESDAGSSVGR 429
Query: 66 SRKAFTEVTQTELQDPHPSRELPWPMQARRAHRQRNASRDQVVYGSGTKTDRW-ARLLRR 124
R+ +E + E H L ++ R R D + S + D W RLL
Sbjct: 430 RRRTLSESSAWESVSSHDIWVLKQQLELNRPDHGRRRRADSM--SSESTWDAWNERLLEI 487
Query: 125 SKEKTK 130
KE ++
Sbjct: 488 EKEASR 493
>gi|222352177 nuclear factor of kappa light polypeptide gene
enhancer in B-cells inhibitor-like 1 isoform 3 [Homo
sapiens]
Length = 358
Score = 34.7 bits (78), Expect = 0.31
Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 13/70 (18%)
Query: 24 ARGGPSLSS-----VLNELPSAATLRYRD---PGVL-----PWGALEEEEEDGGRSRKAF 70
AR GP + +L+ PSA ++ +D PG + PW + EEEEED + +
Sbjct: 83 ARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREW 142
Query: 71 TEVTQTELQD 80
+ Q EL+D
Sbjct: 143 RQKLQGELED 152
>gi|222352173 nuclear factor of kappa light polypeptide gene
enhancer in B-cells inhibitor-like 1 isoform 1 [Homo
sapiens]
Length = 381
Score = 34.7 bits (78), Expect = 0.31
Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 13/70 (18%)
Query: 24 ARGGPSLSS-----VLNELPSAATLRYRD---PGVL-----PWGALEEEEEDGGRSRKAF 70
AR GP + +L+ PSA ++ +D PG + PW + EEEEED + +
Sbjct: 106 ARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREW 165
Query: 71 TEVTQTELQD 80
+ Q EL+D
Sbjct: 166 RQKLQGELED 175
>gi|222352179 nuclear factor of kappa light polypeptide gene
enhancer in B-cells inhibitor-like 1 isoform 4 [Homo
sapiens]
Length = 343
Score = 34.3 bits (77), Expect = 0.41
Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 15/103 (14%)
Query: 24 ARGGPSLSS-----VLNELPSAATLRYRD---PGVL-----PWGALEEEEEDGGRSRKAF 70
AR GP + +L+ PSA ++ +D PG + PW + EEEEED + +
Sbjct: 83 ARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREW 142
Query: 71 TEVTQTEL--QDPHPSRELPWPMQARRAHRQRNASRDQVVYGS 111
+ Q + + P W + R H Q+ + + GS
Sbjct: 143 RQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGS 185
>gi|222352175 nuclear factor of kappa light polypeptide gene
enhancer in B-cells inhibitor-like 1 isoform 2 [Homo
sapiens]
Length = 366
Score = 34.3 bits (77), Expect = 0.41
Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 15/103 (14%)
Query: 24 ARGGPSLSS-----VLNELPSAATLRYRD---PGVL-----PWGALEEEEEDGGRSRKAF 70
AR GP + +L+ PSA ++ +D PG + PW + EEEEED + +
Sbjct: 106 ARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEEDDASKEREW 165
Query: 71 TEVTQTEL--QDPHPSRELPWPMQARRAHRQRNASRDQVVYGS 111
+ Q + + P W + R H Q+ + + GS
Sbjct: 166 RQKLQGDASHETQEPESFSAWSDRLAREHAQKCQQQQREAEGS 208
>gi|195927059 axin 2 [Homo sapiens]
Length = 843
Score = 32.3 bits (72), Expect = 1.5
Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 13/111 (11%)
Query: 6 TLESEAWGSSRGWLAPREARGGPSLSSVLNELPSAATLRYRDPGVLPWGALEEEEEDGGR 65
T+ SE +G SRG P+ G L A PG GAL+ E+G R
Sbjct: 564 TMPSEQFGGSRGSTLPKRNGKGTEPGLALPAREGGA------PGGA--GALQLPREEGDR 615
Query: 66 SRKAFTEVTQTELQD---PH--PSRELPWPMQARRAHRQRNASRDQVVYGS 111
S+ + + ++E Q PH S + +P+++ R+ ASR + G+
Sbjct: 616 SQDVWQWMLESERQSKPKPHSAQSTKKAYPLESARSSPGERASRHHLWGGN 666
>gi|33589848 transferrin receptor 2 [Homo sapiens]
Length = 801
Score = 32.3 bits (72), Expect = 1.5
Identities = 20/50 (40%), Positives = 23/50 (46%), Gaps = 7/50 (14%)
Query: 54 GALEEEEEDGGRSRKAFTEVTQTELQDPHP--SRE-----LPWPMQARRA 96
G LEEEEEDG + EL+ P P SR +PW RRA
Sbjct: 32 GHLEEEEEDGEEGAETLAHFCPMELRGPEPLGSRPRQPNLIPWAAAGRRA 81
>gi|166795252 hypothetical protein LOC23359 [Homo sapiens]
Length = 539
Score = 31.6 bits (70), Expect = 2.6
Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 4/77 (5%)
Query: 568 TCSPAARTFRASAANFF-FPLVLLLGLAISSVPLLYSIFLIPPSKLC---GPFRGQSSIW 623
TC+P+ R +F P L +AI+S LLY L PP + P +SI
Sbjct: 255 TCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPYEAVVGQPPASQVTSIG 314
Query: 624 AQIPESISSLPETTQNF 640
Q+ ES S P T+ F
Sbjct: 315 QQVAESSSGDPNTSAGF 331
>gi|31881740 solute carrier family 12 (potassium/chloride
transporters), member 9 [Homo sapiens]
Length = 914
Score = 31.6 bits (70), Expect = 2.6
Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 11/84 (13%)
Query: 132 GLRSL-QPWAWTLKR-------IGG--QFGAGTESYFSLLRFLLLLNVLASVLMACMTLL 181
GLR L Q + W L +GG GAG + S L FLL+ LASVL++ + +
Sbjct: 156 GLRVLPQGYGWNLLYGSLLLGLVGGVCTLGAGLYARASFLTFLLVSGSLASVLISFVAVG 215
Query: 182 PTWLGGAP-PGPPGPDISSPCGSY 204
P + P PGP G + G +
Sbjct: 216 PRDIRLTPRPGPNGSSLPPRFGHF 239
>gi|41349499 proteolipid protein 1 isoform 1 [Homo sapiens]
Length = 277
Score = 31.2 bits (69), Expect = 3.4
Identities = 12/26 (46%), Positives = 18/26 (69%)
Query: 523 PDEVLGLIYAQTVVWVGSFFCPLLPL 548
PD+ +G+ YA TVVW+ F C +P+
Sbjct: 149 PDKFVGITYALTVVWLLVFACSAVPV 174
>gi|192449447 proteolipid protein 1 isoform 1 [Homo sapiens]
Length = 277
Score = 31.2 bits (69), Expect = 3.4
Identities = 12/26 (46%), Positives = 18/26 (69%)
Query: 523 PDEVLGLIYAQTVVWVGSFFCPLLPL 548
PD+ +G+ YA TVVW+ F C +P+
Sbjct: 149 PDKFVGITYALTVVWLLVFACSAVPV 174
>gi|239757751 PREDICTED: hypothetical protein [Homo sapiens]
Length = 327
Score = 31.2 bits (69), Expect = 3.4
Identities = 37/139 (26%), Positives = 53/139 (38%), Gaps = 12/139 (8%)
Query: 25 RGGPSLSSVLNELPSAATLRYR-------DPGVLPWGALEEEEEDGGRSRKAFTEVTQTE 77
R GP L L A LR R DP + G +E + G+ + + +
Sbjct: 105 RSGPGLHGALGPDTGGAKLRVRPRRTPPRDPSLPVLGGAKEPGQVEGQEEEGVVRLLEPT 164
Query: 78 LQDPHPSRELPWPMQARRAHRQRNASRDQVVYGSGTKT-DRWARLLRRSKEKTKEGLRSL 136
Q P PS P A RA R+ N D + G + R + R ++ L S
Sbjct: 165 PQPPPPS---PPRGLADRAPRRLNTPPDTLAPRRGVLSGHRLGLQIPRDPDQGSGSLSSQ 221
Query: 137 QPWAWTLKRIGGQFGAGTE 155
P + L R GQF G++
Sbjct: 222 LP-TFPLLRKSGQFRDGSQ 239
>gi|239752261 PREDICTED: hypothetical protein XP_002348184 [Homo
sapiens]
Length = 264
Score = 31.2 bits (69), Expect = 3.4
Identities = 37/139 (26%), Positives = 53/139 (38%), Gaps = 12/139 (8%)
Query: 25 RGGPSLSSVLNELPSAATLRYR-------DPGVLPWGALEEEEEDGGRSRKAFTEVTQTE 77
R GP L L A LR R DP + G +E + G+ + + +
Sbjct: 42 RSGPGLHGALGPDTGGAKLRVRPRRTPPRDPSLPVLGGAKEPGQVEGQEEEGVVRLLEPT 101
Query: 78 LQDPHPSRELPWPMQARRAHRQRNASRDQVVYGSGTKT-DRWARLLRRSKEKTKEGLRSL 136
Q P PS P A RA R+ N D + G + R + R ++ L S
Sbjct: 102 PQPPPPS---PPRGLADRAPRRLNTPPDTLAPRRGVLSGHRLGLQIPRDPDQGSGSLSSQ 158
Query: 137 QPWAWTLKRIGGQFGAGTE 155
P + L R GQF G++
Sbjct: 159 LP-TFPLLRKSGQFRDGSQ 176
>gi|239746774 PREDICTED: hypothetical protein XP_002343845 [Homo
sapiens]
Length = 264
Score = 31.2 bits (69), Expect = 3.4
Identities = 37/139 (26%), Positives = 53/139 (38%), Gaps = 12/139 (8%)
Query: 25 RGGPSLSSVLNELPSAATLRYR-------DPGVLPWGALEEEEEDGGRSRKAFTEVTQTE 77
R GP L L A LR R DP + G +E + G+ + + +
Sbjct: 42 RSGPGLHGALGPDTGGAKLRVRPRRTPPRDPSLPVLGGAKEPGQVEGQEEEGVVRLLEPT 101
Query: 78 LQDPHPSRELPWPMQARRAHRQRNASRDQVVYGSGTKT-DRWARLLRRSKEKTKEGLRSL 136
Q P PS P A RA R+ N D + G + R + R ++ L S
Sbjct: 102 PQPPPPS---PPRGLADRAPRRLNTPPDTLAPRRGVLSGHRLGLQIPRDPDQGSGSLSSQ 158
Query: 137 QPWAWTLKRIGGQFGAGTE 155
P + L R GQF G++
Sbjct: 159 LP-TFPLLRKSGQFRDGSQ 176
>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
Length = 1312
Score = 31.2 bits (69), Expect = 3.4
Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 56 LEEEEEDGGR-SRKAFTEVTQTELQDPHPSRELPWPMQARRAHRQRNASRDQVVYGSGTK 114
+EE++E+ R + E Q +LQ+ R L RR +R A R+Q +
Sbjct: 398 IEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQLE 457
Query: 115 TDRWARLLRRSKEKTKEGLRSLQ 137
R + L+R ++ L+SLQ
Sbjct: 458 EQRQSERLQRQLQQEHAYLKSLQ 480
>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
Length = 1303
Score = 31.2 bits (69), Expect = 3.4
Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 56 LEEEEEDGGR-SRKAFTEVTQTELQDPHPSRELPWPMQARRAHRQRNASRDQVVYGSGTK 114
+EE++E+ R + E Q +LQ+ R L RR +R A R+Q +
Sbjct: 398 IEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQLE 457
Query: 115 TDRWARLLRRSKEKTKEGLRSLQ 137
R + L+R ++ L+SLQ
Sbjct: 458 EQRQSERLQRQLQQEHAYLKSLQ 480
>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
Length = 1332
Score = 31.2 bits (69), Expect = 3.4
Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 56 LEEEEEDGGR-SRKAFTEVTQTELQDPHPSRELPWPMQARRAHRQRNASRDQVVYGSGTK 114
+EE++E+ R + E Q +LQ+ R L RR +R A R+Q +
Sbjct: 398 IEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQLE 457
Query: 115 TDRWARLLRRSKEKTKEGLRSLQ 137
R + L+R ++ L+SLQ
Sbjct: 458 EQRQSERLQRQLQQEHAYLKSLQ 480
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.139 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,844,715
Number of Sequences: 37866
Number of extensions: 1321155
Number of successful extensions: 6665
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 6570
Number of HSP's gapped (non-prelim): 64
length of query: 706
length of database: 18,247,518
effective HSP length: 109
effective length of query: 597
effective length of database: 14,120,124
effective search space: 8429714028
effective search space used: 8429714028
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.