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Search of human proteins with 21361699
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361699 sphingosine kinase 2 [Homo sapiens]
(654 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361699 sphingosine kinase 2 [Homo sapiens] 1347 0.0
gi|217272885 sphingosine kinase 1 isoform 3 [Homo sapiens] 253 4e-67
gi|217272883 sphingosine kinase 1 isoform 3 [Homo sapiens] 253 4e-67
gi|21361088 sphingosine kinase 1 isoform 1 [Homo sapiens] 253 4e-67
gi|217272880 sphingosine kinase 1 isoform 2 [Homo sapiens] 253 4e-67
gi|20336726 ceramide kinase [Homo sapiens] 102 9e-22
gi|8922701 acylglycerol kinase [Homo sapiens] 74 3e-13
gi|41680688 ceramide kinase-like isoform a [Homo sapiens] 67 7e-11
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 55 2e-07
gi|115387123 protocadherin 15 isoform CD1-4 precursor [Homo sapi... 55 2e-07
gi|218505798 protocadherin 15 isoform CD1-10 precursor [Homo sap... 55 2e-07
gi|218505785 protocadherin 15 isoform CD1-9 precursor [Homo sapi... 55 2e-07
gi|218505783 protocadherin 15 isoform CD1-8 precursor [Homo sapi... 55 2e-07
gi|218505781 protocadherin 15 isoform CD1-7 precursor [Homo sapi... 55 2e-07
gi|218505779 protocadherin 15 isoform CD1-6 precursor [Homo sapi... 55 2e-07
gi|218505777 protocadherin 15 isoform CD1-2 precursor [Homo sapi... 55 2e-07
gi|218505775 protocadherin 15 isoform CD1-1 precursor [Homo sapi... 55 2e-07
gi|160707881 formin 2 [Homo sapiens] 55 3e-07
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 53 8e-07
gi|71896723 ceramide kinase-like isoform b [Homo sapiens] 52 1e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni... 52 1e-06
gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi... 51 3e-06
gi|55750053 atrophin-1 [Homo sapiens] 51 3e-06
gi|55750041 atrophin-1 [Homo sapiens] 51 3e-06
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 50 7e-06
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 50 9e-06
gi|239750506 PREDICTED: hypothetical protein XP_002347417 [Homo ... 49 1e-05
gi|239744803 PREDICTED: hypothetical protein XP_002343287 [Homo ... 49 1e-05
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 49 1e-05
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 49 1e-05
>gi|21361699 sphingosine kinase 2 [Homo sapiens]
Length = 654
Score = 1347 bits (3487), Expect = 0.0
Identities = 654/654 (100%), Positives = 654/654 (100%)
Query: 1 MNGHLEAEEQQDQRPDQELTGSWGHGPRSTLVRAKAMAPPPPPLAASTPLLHGEFGSYPA 60
MNGHLEAEEQQDQRPDQELTGSWGHGPRSTLVRAKAMAPPPPPLAASTPLLHGEFGSYPA
Sbjct: 1 MNGHLEAEEQQDQRPDQELTGSWGHGPRSTLVRAKAMAPPPPPLAASTPLLHGEFGSYPA 60
Query: 61 RGPRFALTLTSQALHIQRLRPKPEARPRGGLVPLAEVSGCCTLRSRSPSDSAAYFCIYTY 120
RGPRFALTLTSQALHIQRLRPKPEARPRGGLVPLAEVSGCCTLRSRSPSDSAAYFCIYTY
Sbjct: 61 RGPRFALTLTSQALHIQRLRPKPEARPRGGLVPLAEVSGCCTLRSRSPSDSAAYFCIYTY 120
Query: 121 PRGRRGARRRATRTFRADGAATYEENRAEAQRWATALTCLLRGLPLPGDGEITPDLLPRP 180
PRGRRGARRRATRTFRADGAATYEENRAEAQRWATALTCLLRGLPLPGDGEITPDLLPRP
Sbjct: 121 PRGRRGARRRATRTFRADGAATYEENRAEAQRWATALTCLLRGLPLPGDGEITPDLLPRP 180
Query: 181 PRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELVQGLSLSEWDG 240
PRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELVQGLSLSEWDG
Sbjct: 181 PRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELVQGLSLSEWDG 240
Query: 241 IVTVSGDGLLHEVLNGLLDRPDWEEAVKMPVGILPCGSGNALAGAVNQHGGFEPALGLDL 300
IVTVSGDGLLHEVLNGLLDRPDWEEAVKMPVGILPCGSGNALAGAVNQHGGFEPALGLDL
Sbjct: 241 IVTVSGDGLLHEVLNGLLDRPDWEEAVKMPVGILPCGSGNALAGAVNQHGGFEPALGLDL 300
Query: 301 LLNCSLLLCRGGGHPLDLLSVTLASGSRCFSFLSVAWGFVSDVDIQSERFRALGSARFTL 360
LLNCSLLLCRGGGHPLDLLSVTLASGSRCFSFLSVAWGFVSDVDIQSERFRALGSARFTL
Sbjct: 301 LLNCSLLLCRGGGHPLDLLSVTLASGSRCFSFLSVAWGFVSDVDIQSERFRALGSARFTL 360
Query: 361 GTVLGLATLHTYRGRLSYLPATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSV 420
GTVLGLATLHTYRGRLSYLPATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSV
Sbjct: 361 GTVLGLATLHTYRGRLSYLPATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSV 420
Query: 421 SDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKA 480
SDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKA
Sbjct: 421 SDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKA 480
Query: 481 ALHSPVSEGAPVIPPSSGLPLPTPDARVGASTCGPPDHLLPPLGTPLPPDWVTLEGDFVL 540
ALHSPVSEGAPVIPPSSGLPLPTPDARVGASTCGPPDHLLPPLGTPLPPDWVTLEGDFVL
Sbjct: 481 ALHSPVSEGAPVIPPSSGLPLPTPDARVGASTCGPPDHLLPPLGTPLPPDWVTLEGDFVL 540
Query: 541 MLAISPSHLGADLVAAPHARFDDGLVHLCWVRSGISRAALLRLFLAMERGSHFSLGCPQL 600
MLAISPSHLGADLVAAPHARFDDGLVHLCWVRSGISRAALLRLFLAMERGSHFSLGCPQL
Sbjct: 541 MLAISPSHLGADLVAAPHARFDDGLVHLCWVRSGISRAALLRLFLAMERGSHFSLGCPQL 600
Query: 601 GYAAARAFRLEPLTPRGVLTVDGEQVEYGPLQAQMHPGIGTLLTGPPGCPGREP 654
GYAAARAFRLEPLTPRGVLTVDGEQVEYGPLQAQMHPGIGTLLTGPPGCPGREP
Sbjct: 601 GYAAARAFRLEPLTPRGVLTVDGEQVEYGPLQAQMHPGIGTLLTGPPGCPGREP 654
>gi|217272885 sphingosine kinase 1 isoform 3 [Homo sapiens]
Length = 384
Score = 253 bits (646), Expect = 4e-67
Identities = 130/245 (53%), Positives = 173/245 (70%), Gaps = 14/245 (5%)
Query: 176 LLPRPPRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELVQGLSL 235
+LPRP R+L+L+NP GG+G A Q ++HV P+++EA +SF L+ TER+NHARELV+ L
Sbjct: 10 VLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEEL 69
Query: 236 SEWDGIVTVSGDGLLHEVLNGLLDRPDWEEAVKMPVGILPCGSGNALAGAVNQHGGFEPA 295
WD +V +SGDGL+HEV+NGL++RPDWE A++ P+ LP GSGNALA ++N + G+E
Sbjct: 70 GRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAGYEQV 129
Query: 296 LGLDLLLNCSLLLCRGGGHPLDLLSVTLASGSRCFSFLSVAWGFVSDVDIQSERFRALGS 355
DLL NC+LLLCR P++LLS+ ASG R FS LS+AWGF++DVD++SE++R LG
Sbjct: 130 TNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYRRLGE 189
Query: 356 ARFTLGTVLGLATLHTYRGRLSYLP----ATVEPAS-------PTPAHSLPRAK---SEL 401
RFTLGT L LA L TYRGRL+YLP + PAS P AH +P + S
Sbjct: 190 MRFTLGTFLRLAALRTYRGRLAYLPVGRVGSKTPASPVVVQQGPVDAHLVPLEEPVPSHW 249
Query: 402 TLTPD 406
T+ PD
Sbjct: 250 TVVPD 254
Score = 123 bits (308), Expect = 6e-28
Identities = 69/151 (45%), Positives = 91/151 (60%), Gaps = 9/151 (5%)
Query: 504 PDARVGASTC--------GPPDHLLPPLGTPLPPDWVTL-EGDFVLMLAISPSHLGADLV 554
P RVG+ T GP D L PL P+P W + + DFVL+LA+ SHLG+++
Sbjct: 214 PVGRVGSKTPASPVVVQQGPVDAHLVPLEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMF 273
Query: 555 AAPHARFDDGLVHLCWVRSGISRAALLRLFLAMERGSHFSLGCPQLGYAAARAFRLEPLT 614
AAP R G++HL +VR+G+SRA LLRLFLAME+G H CP L Y AFRLEP
Sbjct: 274 AAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKD 333
Query: 615 PRGVLTVDGEQVEYGPLQAQMHPGIGTLLTG 645
+GV VDGE + +Q Q+HP +++G
Sbjct: 334 GKGVFAVDGELMVSEAVQGQVHPNYFWMVSG 364
>gi|217272883 sphingosine kinase 1 isoform 3 [Homo sapiens]
Length = 384
Score = 253 bits (646), Expect = 4e-67
Identities = 130/245 (53%), Positives = 173/245 (70%), Gaps = 14/245 (5%)
Query: 176 LLPRPPRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELVQGLSL 235
+LPRP R+L+L+NP GG+G A Q ++HV P+++EA +SF L+ TER+NHARELV+ L
Sbjct: 10 VLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEEL 69
Query: 236 SEWDGIVTVSGDGLLHEVLNGLLDRPDWEEAVKMPVGILPCGSGNALAGAVNQHGGFEPA 295
WD +V +SGDGL+HEV+NGL++RPDWE A++ P+ LP GSGNALA ++N + G+E
Sbjct: 70 GRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAGYEQV 129
Query: 296 LGLDLLLNCSLLLCRGGGHPLDLLSVTLASGSRCFSFLSVAWGFVSDVDIQSERFRALGS 355
DLL NC+LLLCR P++LLS+ ASG R FS LS+AWGF++DVD++SE++R LG
Sbjct: 130 TNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYRRLGE 189
Query: 356 ARFTLGTVLGLATLHTYRGRLSYLP----ATVEPAS-------PTPAHSLPRAK---SEL 401
RFTLGT L LA L TYRGRL+YLP + PAS P AH +P + S
Sbjct: 190 MRFTLGTFLRLAALRTYRGRLAYLPVGRVGSKTPASPVVVQQGPVDAHLVPLEEPVPSHW 249
Query: 402 TLTPD 406
T+ PD
Sbjct: 250 TVVPD 254
Score = 123 bits (308), Expect = 6e-28
Identities = 69/151 (45%), Positives = 91/151 (60%), Gaps = 9/151 (5%)
Query: 504 PDARVGASTC--------GPPDHLLPPLGTPLPPDWVTL-EGDFVLMLAISPSHLGADLV 554
P RVG+ T GP D L PL P+P W + + DFVL+LA+ SHLG+++
Sbjct: 214 PVGRVGSKTPASPVVVQQGPVDAHLVPLEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMF 273
Query: 555 AAPHARFDDGLVHLCWVRSGISRAALLRLFLAMERGSHFSLGCPQLGYAAARAFRLEPLT 614
AAP R G++HL +VR+G+SRA LLRLFLAME+G H CP L Y AFRLEP
Sbjct: 274 AAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKD 333
Query: 615 PRGVLTVDGEQVEYGPLQAQMHPGIGTLLTG 645
+GV VDGE + +Q Q+HP +++G
Sbjct: 334 GKGVFAVDGELMVSEAVQGQVHPNYFWMVSG 364
>gi|21361088 sphingosine kinase 1 isoform 1 [Homo sapiens]
Length = 398
Score = 253 bits (646), Expect = 4e-67
Identities = 130/245 (53%), Positives = 173/245 (70%), Gaps = 14/245 (5%)
Query: 176 LLPRPPRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELVQGLSL 235
+LPRP R+L+L+NP GG+G A Q ++HV P+++EA +SF L+ TER+NHARELV+ L
Sbjct: 24 VLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEEL 83
Query: 236 SEWDGIVTVSGDGLLHEVLNGLLDRPDWEEAVKMPVGILPCGSGNALAGAVNQHGGFEPA 295
WD +V +SGDGL+HEV+NGL++RPDWE A++ P+ LP GSGNALA ++N + G+E
Sbjct: 84 GRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAGYEQV 143
Query: 296 LGLDLLLNCSLLLCRGGGHPLDLLSVTLASGSRCFSFLSVAWGFVSDVDIQSERFRALGS 355
DLL NC+LLLCR P++LLS+ ASG R FS LS+AWGF++DVD++SE++R LG
Sbjct: 144 TNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYRRLGE 203
Query: 356 ARFTLGTVLGLATLHTYRGRLSYLP----ATVEPAS-------PTPAHSLPRAK---SEL 401
RFTLGT L LA L TYRGRL+YLP + PAS P AH +P + S
Sbjct: 204 MRFTLGTFLRLAALRTYRGRLAYLPVGRVGSKTPASPVVVQQGPVDAHLVPLEEPVPSHW 263
Query: 402 TLTPD 406
T+ PD
Sbjct: 264 TVVPD 268
Score = 123 bits (308), Expect = 6e-28
Identities = 69/151 (45%), Positives = 91/151 (60%), Gaps = 9/151 (5%)
Query: 504 PDARVGASTC--------GPPDHLLPPLGTPLPPDWVTL-EGDFVLMLAISPSHLGADLV 554
P RVG+ T GP D L PL P+P W + + DFVL+LA+ SHLG+++
Sbjct: 228 PVGRVGSKTPASPVVVQQGPVDAHLVPLEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMF 287
Query: 555 AAPHARFDDGLVHLCWVRSGISRAALLRLFLAMERGSHFSLGCPQLGYAAARAFRLEPLT 614
AAP R G++HL +VR+G+SRA LLRLFLAME+G H CP L Y AFRLEP
Sbjct: 288 AAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKD 347
Query: 615 PRGVLTVDGEQVEYGPLQAQMHPGIGTLLTG 645
+GV VDGE + +Q Q+HP +++G
Sbjct: 348 GKGVFAVDGELMVSEAVQGQVHPNYFWMVSG 378
>gi|217272880 sphingosine kinase 1 isoform 2 [Homo sapiens]
Length = 470
Score = 253 bits (646), Expect = 4e-67
Identities = 130/245 (53%), Positives = 173/245 (70%), Gaps = 14/245 (5%)
Query: 176 LLPRPPRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELVQGLSL 235
+LPRP R+L+L+NP GG+G A Q ++HV P+++EA +SF L+ TER+NHARELV+ L
Sbjct: 96 VLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFTLMLTERRNHARELVRSEEL 155
Query: 236 SEWDGIVTVSGDGLLHEVLNGLLDRPDWEEAVKMPVGILPCGSGNALAGAVNQHGGFEPA 295
WD +V +SGDGL+HEV+NGL++RPDWE A++ P+ LP GSGNALA ++N + G+E
Sbjct: 156 GRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPAGSGNALAASLNHYAGYEQV 215
Query: 296 LGLDLLLNCSLLLCRGGGHPLDLLSVTLASGSRCFSFLSVAWGFVSDVDIQSERFRALGS 355
DLL NC+LLLCR P++LLS+ ASG R FS LS+AWGF++DVD++SE++R LG
Sbjct: 216 TNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYRRLGE 275
Query: 356 ARFTLGTVLGLATLHTYRGRLSYLP----ATVEPAS-------PTPAHSLPRAK---SEL 401
RFTLGT L LA L TYRGRL+YLP + PAS P AH +P + S
Sbjct: 276 MRFTLGTFLRLAALRTYRGRLAYLPVGRVGSKTPASPVVVQQGPVDAHLVPLEEPVPSHW 335
Query: 402 TLTPD 406
T+ PD
Sbjct: 336 TVVPD 340
Score = 123 bits (308), Expect = 6e-28
Identities = 69/151 (45%), Positives = 91/151 (60%), Gaps = 9/151 (5%)
Query: 504 PDARVGASTC--------GPPDHLLPPLGTPLPPDWVTL-EGDFVLMLAISPSHLGADLV 554
P RVG+ T GP D L PL P+P W + + DFVL+LA+ SHLG+++
Sbjct: 300 PVGRVGSKTPASPVVVQQGPVDAHLVPLEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMF 359
Query: 555 AAPHARFDDGLVHLCWVRSGISRAALLRLFLAMERGSHFSLGCPQLGYAAARAFRLEPLT 614
AAP R G++HL +VR+G+SRA LLRLFLAME+G H CP L Y AFRLEP
Sbjct: 360 AAPMGRCAAGVMHLFYVRAGVSRAMLLRLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKD 419
Query: 615 PRGVLTVDGEQVEYGPLQAQMHPGIGTLLTG 645
+GV VDGE + +Q Q+HP +++G
Sbjct: 420 GKGVFAVDGELMVSEAVQGQVHPNYFWMVSG 450
>gi|20336726 ceramide kinase [Homo sapiens]
Length = 537
Score = 102 bits (255), Expect = 9e-22
Identities = 70/230 (30%), Positives = 114/230 (49%), Gaps = 21/230 (9%)
Query: 171 EITPDLLPRPPRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELV 230
E+ L RP LL+ +NPFGG+G + + V P+ + A ++ ++I TE N A+E +
Sbjct: 121 EMLEKLTSRPKHLLVFINPFGGKGQGKRIYERKVAPLFTLASITTDIIVTEHANQAKETL 180
Query: 231 QGLSLSEWDGIVTVSGDGLLHEVLNGLLDR--------PDWEEAVKMP----VGILPCGS 278
+++ ++DGIV V GDG+ EVL+GL+ R + AV +P +GI+P GS
Sbjct: 181 YEINIDKYDGIVCVGGDGMFSEVLHGLIGRTQRSAGVDQNHPRAVLVPSSLRIGIIPAGS 240
Query: 279 GNALAGAVNQHGGFEPALGLDLLLNCSLLLCRGGGHPLDLLSVTLASGSRCFSFLSVAWG 338
+ + + +G +L + G +D+ SV S +S + +G
Sbjct: 241 TDCVCYS---------TVGTSDAETSALHIVVGDSLAMDVSSVHHNSTLLRYSVSLLGYG 291
Query: 339 FVSDVDIQSERFRALGSARFTLGTVLGLATLHTYRGRLSYLPATVEPASP 388
F D+ SE+ R LG AR+ + + H Y G +S+LPA SP
Sbjct: 292 FYGDIIKDSEKKRWLGLARYDFSGLKTFLSHHCYEGTVSFLPAQHTVGSP 341
>gi|8922701 acylglycerol kinase [Homo sapiens]
Length = 422
Score = 74.3 bits (181), Expect = 3e-13
Identities = 62/259 (23%), Positives = 113/259 (43%), Gaps = 26/259 (10%)
Query: 185 LLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELVQGLSLSEWDGIVTV 244
+ +NP +G A + + P++ +G+ +++T+ + A++L++ + D I+
Sbjct: 65 VFLNPAACKGKARTLFEKNAAPILHLSGMDVTIVKTDYEGQAKKLLE--LMENTDVIIVA 122
Query: 245 SGDGLLHEVLNGLLDRPDWEEAVKMPVGILPCGSGNALAGAVNQHGGFEPALGLDLLLNC 304
GDG L EV+ G+L R D K+P+G +P G ++L+ + G + + + +
Sbjct: 123 GGDGTLQEVVTGVLRRTDEATFSKIPIGFIPLGETSSLSHTLFAESGNK----VQHITDA 178
Query: 305 SLLLCRGGGHPLDLLSVTLASGSRCFSFLSVAWGFVSDVDIQSERFRALGSARFTLGTVL 364
+L + +G PLD+L + F+ + WG D ++ ++ LG +
Sbjct: 179 TLAIVKGETVPLDVLQIKGEKEQPVFAMTGLRWGSFRDAGVKVSKYWYLGPLKIKAAHF- 237
Query: 365 GLATL----HTYRGRLSYLPATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSV 420
+TL T++ +SY T P P E TP P + L R
Sbjct: 238 -FSTLKEWPQTHQASISYTGPTERP---------PNEPEE---TPVQRPSLYRRILRRLA 284
Query: 421 SDLPLPLPQPALASPGSPE 439
S PQ AL+ SPE
Sbjct: 285 S--YWAQPQDALSQEVSPE 301
>gi|41680688 ceramide kinase-like isoform a [Homo sapiens]
Length = 532
Score = 66.6 bits (161), Expect = 7e-11
Identities = 58/214 (27%), Positives = 97/214 (45%), Gaps = 22/214 (10%)
Query: 179 RPPRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELVQGLSLSEW 238
RP L +L+NP + A Q V P++ AG+ ++ E + HA L++ L +
Sbjct: 165 RPKSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGF 224
Query: 239 DGIVTVSGDGLLHEVLNGLL-----------DRPDWEEAVKMPVGILPCGSGNALAGAVN 287
DG+V V GDG EV + LL DR ++P+G++P GS N LA +++
Sbjct: 225 DGVVCVGGDGSASEVAHALLLRAQKNAGMETDRILTPVRAQLPLGLIPAGSTNVLAHSLH 284
Query: 288 QHGGFEPALGLDLLLNCSLLLCRGGGHPLDLLSVTLASGSRCFSFLSVAWGFVSDVDIQS 347
G+ ++ +L + G +D+ + + A F F S +GF +
Sbjct: 285 ---------GVPHVITATLHIIMGHVQLVDVCTFSTAGKLLRFGF-SAMFGFGGRTLALA 334
Query: 348 ERFRALG-SARFTLGTVLGLATLHTYRGRLSYLP 380
E++R + + R V LA L +S+LP
Sbjct: 335 EKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLP 368
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 55.5 bits (132), Expect = 2e-07
Identities = 55/190 (28%), Positives = 72/190 (37%), Gaps = 21/190 (11%)
Query: 378 YLPATVEPASP--TPAHSLPRAKSELTLTPDPAPPMAH--SPLHRSVSDLPLPLPQPALA 433
+ P P SP TP P + + L P+PP + SP P PL P L
Sbjct: 677 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 736
Query: 434 SPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVI 493
P SP P +S + P PL P L PP P + SP+++ P
Sbjct: 737 VPPSPPASPPMSPSATPPPRV--------PPLLAAPPLQVPPSPPASLPMSPLAKPPPQA 788
Query: 494 PPSSGLP----LPTPDARVGASTCGPPDHLLP--PLGTPLPPDWVTLEGDFVLMLAISPS 547
PP+ P LP+P A P LP PL TP P L +L + PS
Sbjct: 789 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP---LLQVPPS 845
Query: 548 HLGADLVAAP 557
+ + AP
Sbjct: 846 PPASPTLQAP 855
Score = 48.9 bits (115), Expect = 1e-05
Identities = 56/209 (26%), Positives = 82/209 (39%), Gaps = 31/209 (14%)
Query: 355 SARFTLGTVLGLATL--HTYRGRLSYL-PATVEPASPTPAHSLPRAKSELTLTP-DPAPP 410
S+ T+ + L++L H+ + LS L +E S SL + LT P + P
Sbjct: 481 SSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPS 540
Query: 411 MAHSPLHRSVSDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPL 470
+A PL + + PL P L +P P P P+ AP P PL
Sbjct: 541 LAPPPLQTASA----PLTTPHLETPPCPAPCPL------------------QAP--PSPL 576
Query: 471 LSSPPGSPKAALHSPVSEGAPVI--PPSSGLPLPTPDARVGASTCGPPDHLLPPLGTPLP 528
+ PP +P +++ +P + P + PP GLP P PP LPPL P
Sbjct: 577 TTPPPETP-SSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPS 635
Query: 529 PDWVTLEGDFVLMLAISPSHLGADLVAAP 557
P +P+ L L+ AP
Sbjct: 636 PPASPPLSPLATPSPQAPNALAVHLLQAP 664
Score = 44.3 bits (103), Expect = 4e-04
Identities = 48/154 (31%), Positives = 59/154 (38%), Gaps = 20/154 (12%)
Query: 385 PASPTPAHSL---PRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEPL 441
PASP + S PR L P PP + L S P P PALA+P
Sbjct: 742 PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATP------ 795
Query: 442 PILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIPPSSGL-- 499
P+ +L G + A L PL + PP +P L +P+ + P P S L
Sbjct: 796 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP-PVLAAPLLQVPPSPPASPTLQA 854
Query: 500 ----PLPTPDARVGASTCGPPDHLLPPLGTPLPP 529
P P PD S GP L G P PP
Sbjct: 855 PRRPPTPGPD----TSVSGPRLTLALAPGPPPPP 884
Score = 42.7 bits (99), Expect = 0.001
Identities = 46/155 (29%), Positives = 56/155 (36%), Gaps = 33/155 (21%)
Query: 385 PASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPA-------LASPGS 437
P SP A P+A L L P APP P +S L P PQ L +P S
Sbjct: 610 PLSPL-ATPPPQAPPXLALPPLQAPPSP--PASPPLSPLATPSPQAPNALAVHLLQAPFS 666
Query: 438 PEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSP---VSEGAPVIP 494
P P P + + P+SP ++PP +L +P V P P
Sbjct: 667 PPP---------SPPVQAPFSPPASPPVSPS---ATPPSQAPPSLAAPPLQVPPSPPASP 714
Query: 495 PSSGLPLPTPDARVGASTCGPPDHLLPPLGTPLPP 529
P S P P A PP PPL P P
Sbjct: 715 PMSPSATPPPQA--------PPPLAAPPLQVPPSP 741
Score = 42.4 bits (98), Expect = 0.001
Identities = 47/162 (29%), Positives = 57/162 (35%), Gaps = 37/162 (22%)
Query: 382 TVEPASPT--PAHSLPRAKSELTLTPDPAPPMAHS-------PLHRSVSDLPLPLPQPAL 432
+ P PT P S+ A T P PA S P RS+S PL PA
Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 254
Query: 433 ASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDP----LLSSPPGSPKAALHSPVSE 488
+ P + G P A P P P L P +P P +
Sbjct: 255 SGPSAR----------GTPR-------APAHPSQPKPKGLQALRPPQVTP------PRKD 291
Query: 489 GAPVIPPSSGLPLPTPD-ARVGASTCGPPDHLLPPLGTPLPP 529
AP + P S PL TP + A PPD+ PL LPP
Sbjct: 292 AAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPP 333
Score = 38.9 bits (89), Expect = 0.015
Identities = 43/142 (30%), Positives = 50/142 (35%), Gaps = 28/142 (19%)
Query: 379 LPATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALASPGSP 438
L A P +P P S+ + L L P P PP + SP L P LA S
Sbjct: 852 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP--------SSTLSGPDLAGHSSS 903
Query: 439 EPLPILSLNG--GGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIP-- 494
L G GPE GGA +P PP + AA H P P
Sbjct: 904 ATSTPEELRGYDSGPE-----GGAAASP---------PPDAELAACHPAAWSRGPAPPLA 949
Query: 495 --PSSGLPLPTPDARVGASTCG 514
+ G PLP P A S G
Sbjct: 950 FRGAPGAPLPWPPATGPGSADG 971
Score = 37.0 bits (84), Expect = 0.057
Identities = 40/135 (29%), Positives = 52/135 (38%), Gaps = 25/135 (18%)
Query: 380 PATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDL--------PLPLPQPA 431
P + P SP+ SL S P APP +P ++ L P L P+
Sbjct: 340 PLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPS 399
Query: 432 LASPGSPEPLPILSLNG----GGPELAGDWGGAGDAP-------LSPDPLLSSPPGSPKA 480
L +P P PL + SL G P L +P SP S+PP SP
Sbjct: 400 LQAP--PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSP-- 455
Query: 481 ALHSPVSEGAPVIPP 495
L +P+S P PP
Sbjct: 456 PLQAPLS--LPASPP 468
Score = 33.5 bits (75), Expect = 0.63
Identities = 44/146 (30%), Positives = 57/146 (39%), Gaps = 29/146 (19%)
Query: 390 PAH-SLPRAKSELTLTPDPAPPMAH--SPLHRSVSDLPLPLPQPALASPGSPEPLPILSL 446
PAH S P+ K L P P +P +S PL P P+ + P P P
Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS-GTKARPVPPPD--- 321
Query: 447 NGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIPPS-SGLPLP--T 503
N P A L P P L++P P++ +P PPS LP P T
Sbjct: 322 NAATPL---------PATLPPSPPLATP---------LPLAPPSPSAPPSLQTLPSPPAT 363
Query: 504 PDARVGASTCGPPDHLLPPLGTPLPP 529
P ++ S PP P L T +PP
Sbjct: 364 PPSQAPPSMTTPPMQAPPSLQT-IPP 388
Score = 33.1 bits (74), Expect = 0.83
Identities = 39/151 (25%), Positives = 53/151 (35%), Gaps = 22/151 (14%)
Query: 373 RGRLSYLPATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPAL 432
+G + P V P A +L S TP P+ A P+P P
Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR------------PVPPPDN 322
Query: 433 ASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPL--LSSPPGSPKAALHSPVSEGA 490
A+ P LP P LA A +P +P L L SPP +P + ++
Sbjct: 323 AATPLPATLP------PSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPP 376
Query: 491 PVIPPSSGL--PLPTPDARVGASTCGPPDHL 519
PPS P+ P + S PP L
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPL 407
Score = 31.2 bits (69), Expect = 3.1
Identities = 51/167 (30%), Positives = 64/167 (38%), Gaps = 29/167 (17%)
Query: 10 QQDQRPDQELTGSWGHGPRSTLVRAKAMAPPPPPLAASTPLLHGEFGSYPARGPRFALTL 69
Q +RP + GPR TL A+AP PPP + +P S GP A
Sbjct: 853 QAPRRPPTPGPDTSVSGPRLTL----ALAPGPPPPPSRSP-------SSTLSGPDLAGHS 901
Query: 70 TSQALHIQRLRPKPEARPRGGLV----PLAEVSGCCTLR-SRSPSDSAAYFCIYTYPRGR 124
+S + LR ++ P GG P AE++ C SR P+ A+ RG
Sbjct: 902 SSATSTPEELRGY-DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF-------RGA 953
Query: 125 RGAR---RRATRTFRADGAATYEENRAEAQRWATALTCLLRGLPLPG 168
GA AT ADG T E E AT L P PG
Sbjct: 954 PGAPLPWPPATGPGSADGLCTIYE--TEGPESATPAPGALDPGPSPG 998
Score = 30.0 bits (66), Expect = 7.0
Identities = 37/123 (30%), Positives = 45/123 (36%), Gaps = 12/123 (9%)
Query: 386 ASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEPLPILS 445
ASP P L A + PAPP+A + PLP P PGS + L +
Sbjct: 924 ASPPPDAELA-ACHPAAWSRGPAPPLAFRGAPGA------PLPWPPATGPGSADGLCTI- 975
Query: 446 LNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIPPSSGLPLPTPD 505
GPE A GA L P P + G A + S +P LPL
Sbjct: 976 YETEGPESATPAPGA----LDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQ 1031
Query: 506 ARV 508
A V
Sbjct: 1032 ASV 1034
>gi|115387123 protocadherin 15 isoform CD1-4 precursor [Homo sapiens]
Length = 1955
Score = 55.1 bits (131), Expect = 2e-07
Identities = 52/155 (33%), Positives = 63/155 (40%), Gaps = 42/155 (27%)
Query: 383 VEPASPTPAHS-LPRAKSELTLTPDPAPP-----MAHSPLHRSVSDLPLPLPQPALASPG 436
+ P+ P HS L R ++ + + P AH P ++S PLP P SP
Sbjct: 1700 LSPSRPCVLHSSLSRRETPICMLPIETERNIFENFAHPP---NISPSACPLPPPPPISPP 1756
Query: 437 SPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIPPS 496
SP P P APL+P PP +L P P PPS
Sbjct: 1757 SPPPAP--------------------APLAP------PPDISPFSLFCP-----PPSPPS 1785
Query: 497 SGLPLPTPD-ARVGASTCGPP-DHLLPPLGTPLPP 529
LPLP P + ST GPP LLPP TPLPP
Sbjct: 1786 IPLPLPPPTFFPLSVSTSGPPTPPLLPPFPTPLPP 1820
Score = 32.0 bits (71), Expect = 1.8
Identities = 30/106 (28%), Positives = 37/106 (34%), Gaps = 23/106 (21%)
Query: 407 PAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLS 466
P+PP A +PL P L P + P P PLP P +
Sbjct: 1756 PSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLP---------------------PPT 1794
Query: 467 PDPLLSSPPGSPKAALHSPVSEGAPVIPPSSGLPLPTPDARVGAST 512
PL S G P L P P+ PP +P P P + ST
Sbjct: 1795 FFPLSVSTSGPPTPPLLPPFP--TPLPPPPPSIPCPPPPSASFLST 1838
>gi|218505798 protocadherin 15 isoform CD1-10 precursor [Homo sapiens]
Length = 1932
Score = 55.1 bits (131), Expect = 2e-07
Identities = 52/155 (33%), Positives = 63/155 (40%), Gaps = 42/155 (27%)
Query: 383 VEPASPTPAHS-LPRAKSELTLTPDPAPP-----MAHSPLHRSVSDLPLPLPQPALASPG 436
+ P+ P HS L R ++ + + P AH P ++S PLP P SP
Sbjct: 1677 LSPSRPCVLHSSLSRRETPICMLPIETERNIFENFAHPP---NISPSACPLPPPPPISPP 1733
Query: 437 SPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIPPS 496
SP P P APL+P PP +L P P PPS
Sbjct: 1734 SPPPAP--------------------APLAP------PPDISPFSLFCP-----PPSPPS 1762
Query: 497 SGLPLPTPD-ARVGASTCGPP-DHLLPPLGTPLPP 529
LPLP P + ST GPP LLPP TPLPP
Sbjct: 1763 IPLPLPPPTFFPLSVSTSGPPTPPLLPPFPTPLPP 1797
Score = 32.0 bits (71), Expect = 1.8
Identities = 30/106 (28%), Positives = 37/106 (34%), Gaps = 23/106 (21%)
Query: 407 PAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLS 466
P+PP A +PL P L P + P P PLP P +
Sbjct: 1733 PSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLP---------------------PPT 1771
Query: 467 PDPLLSSPPGSPKAALHSPVSEGAPVIPPSSGLPLPTPDARVGAST 512
PL S G P L P P+ PP +P P P + ST
Sbjct: 1772 FFPLSVSTSGPPTPPLLPPFP--TPLPPPPPSIPCPPPPSASFLST 1815
>gi|218505785 protocadherin 15 isoform CD1-9 precursor [Homo sapiens]
Length = 1935
Score = 55.1 bits (131), Expect = 2e-07
Identities = 52/155 (33%), Positives = 63/155 (40%), Gaps = 42/155 (27%)
Query: 383 VEPASPTPAHS-LPRAKSELTLTPDPAPP-----MAHSPLHRSVSDLPLPLPQPALASPG 436
+ P+ P HS L R ++ + + P AH P ++S PLP P SP
Sbjct: 1680 LSPSRPCVLHSSLSRRETPICMLPIETERNIFENFAHPP---NISPSACPLPPPPPISPP 1736
Query: 437 SPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIPPS 496
SP P P APL+P PP +L P P PPS
Sbjct: 1737 SPPPAP--------------------APLAP------PPDISPFSLFCP-----PPSPPS 1765
Query: 497 SGLPLPTPD-ARVGASTCGPP-DHLLPPLGTPLPP 529
LPLP P + ST GPP LLPP TPLPP
Sbjct: 1766 IPLPLPPPTFFPLSVSTSGPPTPPLLPPFPTPLPP 1800
Score = 32.0 bits (71), Expect = 1.8
Identities = 30/106 (28%), Positives = 37/106 (34%), Gaps = 23/106 (21%)
Query: 407 PAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLS 466
P+PP A +PL P L P + P P PLP P +
Sbjct: 1736 PSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLP---------------------PPT 1774
Query: 467 PDPLLSSPPGSPKAALHSPVSEGAPVIPPSSGLPLPTPDARVGAST 512
PL S G P L P P+ PP +P P P + ST
Sbjct: 1775 FFPLSVSTSGPPTPPLLPPFP--TPLPPPPPSIPCPPPPSASFLST 1818
>gi|218505783 protocadherin 15 isoform CD1-8 precursor [Homo sapiens]
Length = 1915
Score = 55.1 bits (131), Expect = 2e-07
Identities = 52/155 (33%), Positives = 63/155 (40%), Gaps = 42/155 (27%)
Query: 383 VEPASPTPAHS-LPRAKSELTLTPDPAPP-----MAHSPLHRSVSDLPLPLPQPALASPG 436
+ P+ P HS L R ++ + + P AH P ++S PLP P SP
Sbjct: 1660 LSPSRPCVLHSSLSRRETPICMLPIETERNIFENFAHPP---NISPSACPLPPPPPISPP 1716
Query: 437 SPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIPPS 496
SP P P APL+P PP +L P P PPS
Sbjct: 1717 SPPPAP--------------------APLAP------PPDISPFSLFCP-----PPSPPS 1745
Query: 497 SGLPLPTPD-ARVGASTCGPP-DHLLPPLGTPLPP 529
LPLP P + ST GPP LLPP TPLPP
Sbjct: 1746 IPLPLPPPTFFPLSVSTSGPPTPPLLPPFPTPLPP 1780
Score = 32.0 bits (71), Expect = 1.8
Identities = 30/106 (28%), Positives = 37/106 (34%), Gaps = 23/106 (21%)
Query: 407 PAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLS 466
P+PP A +PL P L P + P P PLP P +
Sbjct: 1716 PSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLP---------------------PPT 1754
Query: 467 PDPLLSSPPGSPKAALHSPVSEGAPVIPPSSGLPLPTPDARVGAST 512
PL S G P L P P+ PP +P P P + ST
Sbjct: 1755 FFPLSVSTSGPPTPPLLPPFP--TPLPPPPPSIPCPPPPSASFLST 1798
>gi|218505781 protocadherin 15 isoform CD1-7 precursor [Homo sapiens]
Length = 1952
Score = 55.1 bits (131), Expect = 2e-07
Identities = 52/155 (33%), Positives = 63/155 (40%), Gaps = 42/155 (27%)
Query: 383 VEPASPTPAHS-LPRAKSELTLTPDPAPP-----MAHSPLHRSVSDLPLPLPQPALASPG 436
+ P+ P HS L R ++ + + P AH P ++S PLP P SP
Sbjct: 1697 LSPSRPCVLHSSLSRRETPICMLPIETERNIFENFAHPP---NISPSACPLPPPPPISPP 1753
Query: 437 SPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIPPS 496
SP P P APL+P PP +L P P PPS
Sbjct: 1754 SPPPAP--------------------APLAP------PPDISPFSLFCP-----PPSPPS 1782
Query: 497 SGLPLPTPD-ARVGASTCGPP-DHLLPPLGTPLPP 529
LPLP P + ST GPP LLPP TPLPP
Sbjct: 1783 IPLPLPPPTFFPLSVSTSGPPTPPLLPPFPTPLPP 1817
Score = 32.0 bits (71), Expect = 1.8
Identities = 30/106 (28%), Positives = 37/106 (34%), Gaps = 23/106 (21%)
Query: 407 PAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLS 466
P+PP A +PL P L P + P P PLP P +
Sbjct: 1753 PSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLP---------------------PPT 1791
Query: 467 PDPLLSSPPGSPKAALHSPVSEGAPVIPPSSGLPLPTPDARVGAST 512
PL S G P L P P+ PP +P P P + ST
Sbjct: 1792 FFPLSVSTSGPPTPPLLPPFP--TPLPPPPPSIPCPPPPSASFLST 1835
>gi|218505779 protocadherin 15 isoform CD1-6 precursor [Homo sapiens]
Length = 1886
Score = 55.1 bits (131), Expect = 2e-07
Identities = 52/155 (33%), Positives = 63/155 (40%), Gaps = 42/155 (27%)
Query: 383 VEPASPTPAHS-LPRAKSELTLTPDPAPP-----MAHSPLHRSVSDLPLPLPQPALASPG 436
+ P+ P HS L R ++ + + P AH P ++S PLP P SP
Sbjct: 1631 LSPSRPCVLHSSLSRRETPICMLPIETERNIFENFAHPP---NISPSACPLPPPPPISPP 1687
Query: 437 SPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIPPS 496
SP P P APL+P PP +L P P PPS
Sbjct: 1688 SPPPAP--------------------APLAP------PPDISPFSLFCP-----PPSPPS 1716
Query: 497 SGLPLPTPD-ARVGASTCGPP-DHLLPPLGTPLPP 529
LPLP P + ST GPP LLPP TPLPP
Sbjct: 1717 IPLPLPPPTFFPLSVSTSGPPTPPLLPPFPTPLPP 1751
Score = 32.0 bits (71), Expect = 1.8
Identities = 30/106 (28%), Positives = 37/106 (34%), Gaps = 23/106 (21%)
Query: 407 PAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLS 466
P+PP A +PL P L P + P P PLP P +
Sbjct: 1687 PSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLP---------------------PPT 1725
Query: 467 PDPLLSSPPGSPKAALHSPVSEGAPVIPPSSGLPLPTPDARVGAST 512
PL S G P L P P+ PP +P P P + ST
Sbjct: 1726 FFPLSVSTSGPPTPPLLPPFP--TPLPPPPPSIPCPPPPSASFLST 1769
>gi|218505777 protocadherin 15 isoform CD1-2 precursor [Homo sapiens]
Length = 1957
Score = 55.1 bits (131), Expect = 2e-07
Identities = 52/155 (33%), Positives = 63/155 (40%), Gaps = 42/155 (27%)
Query: 383 VEPASPTPAHS-LPRAKSELTLTPDPAPP-----MAHSPLHRSVSDLPLPLPQPALASPG 436
+ P+ P HS L R ++ + + P AH P ++S PLP P SP
Sbjct: 1702 LSPSRPCVLHSSLSRRETPICMLPIETERNIFENFAHPP---NISPSACPLPPPPPISPP 1758
Query: 437 SPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIPPS 496
SP P P APL+P PP +L P P PPS
Sbjct: 1759 SPPPAP--------------------APLAP------PPDISPFSLFCP-----PPSPPS 1787
Query: 497 SGLPLPTPD-ARVGASTCGPP-DHLLPPLGTPLPP 529
LPLP P + ST GPP LLPP TPLPP
Sbjct: 1788 IPLPLPPPTFFPLSVSTSGPPTPPLLPPFPTPLPP 1822
Score = 32.0 bits (71), Expect = 1.8
Identities = 30/106 (28%), Positives = 37/106 (34%), Gaps = 23/106 (21%)
Query: 407 PAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLS 466
P+PP A +PL P L P + P P PLP P +
Sbjct: 1758 PSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLP---------------------PPT 1796
Query: 467 PDPLLSSPPGSPKAALHSPVSEGAPVIPPSSGLPLPTPDARVGAST 512
PL S G P L P P+ PP +P P P + ST
Sbjct: 1797 FFPLSVSTSGPPTPPLLPPFP--TPLPPPPPSIPCPPPPSASFLST 1840
>gi|218505775 protocadherin 15 isoform CD1-1 precursor [Homo sapiens]
Length = 1962
Score = 55.1 bits (131), Expect = 2e-07
Identities = 52/155 (33%), Positives = 63/155 (40%), Gaps = 42/155 (27%)
Query: 383 VEPASPTPAHS-LPRAKSELTLTPDPAPP-----MAHSPLHRSVSDLPLPLPQPALASPG 436
+ P+ P HS L R ++ + + P AH P ++S PLP P SP
Sbjct: 1707 LSPSRPCVLHSSLSRRETPICMLPIETERNIFENFAHPP---NISPSACPLPPPPPISPP 1763
Query: 437 SPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIPPS 496
SP P P APL+P PP +L P P PPS
Sbjct: 1764 SPPPAP--------------------APLAP------PPDISPFSLFCP-----PPSPPS 1792
Query: 497 SGLPLPTPD-ARVGASTCGPP-DHLLPPLGTPLPP 529
LPLP P + ST GPP LLPP TPLPP
Sbjct: 1793 IPLPLPPPTFFPLSVSTSGPPTPPLLPPFPTPLPP 1827
Score = 32.0 bits (71), Expect = 1.8
Identities = 30/106 (28%), Positives = 37/106 (34%), Gaps = 23/106 (21%)
Query: 407 PAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLS 466
P+PP A +PL P L P + P P PLP P +
Sbjct: 1763 PSPPPAPAPLAPPPDISPFSLFCPPPSPPSIPLPLP---------------------PPT 1801
Query: 467 PDPLLSSPPGSPKAALHSPVSEGAPVIPPSSGLPLPTPDARVGAST 512
PL S G P L P P+ PP +P P P + ST
Sbjct: 1802 FFPLSVSTSGPPTPPLLPPFP--TPLPPPPPSIPCPPPPSASFLST 1845
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 54.7 bits (130), Expect = 3e-07
Identities = 52/168 (30%), Positives = 59/168 (35%), Gaps = 22/168 (13%)
Query: 379 LPATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLP----LPQPALAS 434
LP P P+ A P + P P PP+ + + PLP LP P L
Sbjct: 883 LPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGI---PPPPPLPGAGILPLPPLPG 939
Query: 435 PGSPEPLPILS--------LNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSP- 485
G P P P+ L G G L GAG P P P PP P P
Sbjct: 940 AGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 999
Query: 486 ----VSEGAPVIPPSSGLPLPTPDARVGASTCGPPDHLLPPLGTPLPP 529
G P PP G +P P GA PP LP G P PP
Sbjct: 1000 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI--PPPPPLPGAGIPPPP 1045
Score = 53.5 bits (127), Expect = 6e-07
Identities = 49/150 (32%), Positives = 59/150 (39%), Gaps = 32/150 (21%)
Query: 385 PASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEPLPIL 444
P P P ++P S T P P PP+ + + LP P P L G P P P+
Sbjct: 879 PPPPLPGMTVPTLPS--TAIPQP-PPLQGTEM--------LPPPPPPLPGAGIPPPPPL- 926
Query: 445 SLNGGGPELAGDWGGAGDAPLSPDPL--LSSPPGSPKAALHSP---VSEGAPVIPPSSGL 499
GAG PL P P + PP P AA+ P G P+ PP G
Sbjct: 927 -------------PGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGA 973
Query: 500 PLPTPDARVGASTCGPPDHLLPPLGTPLPP 529
+P P GA PP LP G P PP
Sbjct: 974 GIPPPPPLPGAGI--PPPPPLPGAGIPPPP 1001
Score = 50.1 bits (118), Expect = 7e-06
Identities = 50/154 (32%), Positives = 58/154 (37%), Gaps = 20/154 (12%)
Query: 381 ATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEP 440
A + P P P ++P P P P A PL + +P P P L G P P
Sbjct: 940 AGIPPPPPLPGAAIP---------PPPPLPGAGIPLPPPLPGAGIP-PPPPLPGAGIPPP 989
Query: 441 LPILSLNGGGPELAGDWGGAGDAPLSPDPL--LSSPPGSPKAALHSPVSEGAPVIPPSSG 498
P L G G GAG P P P + PP P A + P IPP
Sbjct: 990 PP---LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1046
Query: 499 LP---LPTPDARVGASTCGPPDHLLPPLGTPLPP 529
LP +P P GA PP LP G P PP
Sbjct: 1047 LPGAGIPPPPPLPGAGI--PPPPPLPGAGIPPPP 1078
Score = 49.7 bits (117), Expect = 9e-06
Identities = 48/154 (31%), Positives = 54/154 (35%), Gaps = 20/154 (12%)
Query: 381 ATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEP 440
A + P P P +P P P P A P + +P P P L G P P
Sbjct: 995 AGIPPPPPLPGAGIP---------PPPPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIPPP 1044
Query: 441 LPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPV-----SEGAPVIPP 495
P L G G GAG P P P PP P P G P PP
Sbjct: 1045 PP---LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1101
Query: 496 SSGLPLPTPDARVGASTCGPPDHLLPPLGTPLPP 529
G+ +P P GA PP LP G P PP
Sbjct: 1102 LPGVGIPPPPPLPGAGI--PPPPPLPGAGIPPPP 1133
Score = 49.3 bits (116), Expect = 1e-05
Identities = 50/156 (32%), Positives = 57/156 (36%), Gaps = 24/156 (15%)
Query: 381 ATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEP 440
A + P P P +P P P P A P + +P P P L G P P
Sbjct: 1028 AGIPPPPPLPGAGIP---------PPPPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIPPP 1077
Query: 441 LPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPV--IPP--- 495
P L G G GAG P P P + PP P P P IPP
Sbjct: 1078 PP---LPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1134
Query: 496 --SSGLPLPTPDARVGASTCGPPDHLLPPLGTPLPP 529
+G+P P P RVG PP LP G P PP
Sbjct: 1135 LPGAGIPPPPPLPRVGI----PPPPPLPGAGIPPPP 1166
Score = 47.0 bits (110), Expect = 6e-05
Identities = 49/156 (31%), Positives = 56/156 (35%), Gaps = 24/156 (15%)
Query: 381 ATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEP 440
A + P P P +P P P P A P + + +P P P L G P P
Sbjct: 1072 AGIPPPPPLPGAGIP---------PPPPLPGAGIPPPPPLPGVGIP-PPPPLPGAGIPPP 1121
Query: 441 LPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPV--IPP--- 495
P L G G GAG P P P + PP P P P IPP
Sbjct: 1122 PP---LPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1178
Query: 496 --SSGLPLPTPDARVGASTCGPPDHLLPPLGTPLPP 529
G+P P P VG PP LP G P PP
Sbjct: 1179 LPGVGIPPPPPLPGVGI----PPPPPLPGAGIPPPP 1210
Score = 47.0 bits (110), Expect = 6e-05
Identities = 50/155 (32%), Positives = 59/155 (38%), Gaps = 21/155 (13%)
Query: 381 ATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLP------QPALAS 434
A + P P P +P L P PP PL R P PLP P L
Sbjct: 1116 AGIPPPPPLPGAGIP-PPPPLPGAGIPPPP----PLPRVGIPPPPPLPGAGIPPPPPLPG 1170
Query: 435 PGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIP 494
G P P P L G G G G P P P PP P + P + P+ P
Sbjct: 1171 AGIPPPPP---LPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPP 1227
Query: 495 PSSGLPLPTPDARVGASTCGPPDHLLPPLGTPLPP 529
P +G+P P P V GPP LLP +G+ P
Sbjct: 1228 PGTGIP-PPPLLPVS----GPP--LLPQVGSSTLP 1255
Score = 33.1 bits (74), Expect = 0.83
Identities = 34/103 (33%), Positives = 42/103 (40%), Gaps = 27/103 (26%)
Query: 437 SPEPLPILSLNGGGPELAGDWGGAGDAPLSPD-------------PLLSSP--PGSPKAA 481
SP+P L L+ L G GGAG+AP SPD L + P P P +
Sbjct: 240 SPQPGAFLGLDRF---LLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSP 296
Query: 482 LHSPVSEGAPVIPPS--------SGLPLPTPDARVGASTCGPP 516
PVSE AP +P + S P P+A G G P
Sbjct: 297 GGLPVSE-APSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAP 338
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 53.1 bits (126), Expect = 8e-07
Identities = 51/163 (31%), Positives = 67/163 (41%), Gaps = 12/163 (7%)
Query: 378 YLPATVEPASPTPAHSLPRAKSELTLTPDP-----APPMAHSPLHRSVSDLPL-PLPQPA 431
+ P P SP P S P E L+P P +PP SPL +LP P P+ +
Sbjct: 512 FSPLEESPLSP-PEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEAS 570
Query: 432 LASPGSPE----PLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVS 487
SP E P P S PE + + ++PLSP P S P+A+ SP
Sbjct: 571 RLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPP 630
Query: 488 EGAPVIPPSSGLPLPTPDARVGASTCGPPDHLL-PPLGTPLPP 529
E +P+ PP P+ P S L PP +PL P
Sbjct: 631 EDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSP 673
Score = 45.8 bits (107), Expect = 1e-04
Identities = 45/137 (32%), Positives = 57/137 (41%), Gaps = 22/137 (16%)
Query: 380 PATVEPASPTP-AHSLPRAKSELTLTPDP-----APPMAHSPLHRSVSDLPL-PLPQPAL 432
P P SP P A L E L+P P +PP S L D P+ P P+ +
Sbjct: 584 PPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESP 643
Query: 433 ASPGSPE-----PLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVS 487
SP PE PLP++S PE ++PLSP P S P+A+ SP
Sbjct: 644 MSP-PPEVSRLSPLPVVSRLSPPPE---------ESPLSPPPEESPTSPPPEASRLSPPP 693
Query: 488 EGAPVIPPSSGLPLPTP 504
E +P PP P P
Sbjct: 694 EDSPTSPPPEDSPASPP 710
Score = 42.0 bits (97), Expect = 0.002
Identities = 48/161 (29%), Positives = 62/161 (38%), Gaps = 31/161 (19%)
Query: 380 PATVEPASPTP-AHSLPRAKSELTLTPDP-----APPMAHSPLHRSVSDLPL-PLPQPAL 432
P P SP P A L EL +P P + P+ SPL + PL P P+ +
Sbjct: 452 PPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSP 511
Query: 433 ASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPV 492
SP PL + P L + PLSP P+A+ SP E +P+
Sbjct: 512 FSPLEESPLSPPEESPPSPAL--------ETPLSP---------PPEASPLSPPFEESPL 554
Query: 493 IPPSSGLPLPTPDARVGASTCGPPDH----LLPPLGTPLPP 529
PP LP P AS PP PP +P+ P
Sbjct: 555 SPPPEELPTSPPPE---ASRLSPPPEESPMSPPPEESPMSP 592
Score = 41.2 bits (95), Expect = 0.003
Identities = 48/171 (28%), Positives = 66/171 (38%), Gaps = 27/171 (15%)
Query: 382 TVEPASPTP--AHSLPRAKSELTLTPDPA----------PPMAHSPLHRSVSDLPLPLPQ 429
+++P P P + P K+ + L P PP SPL + P P
Sbjct: 403 SMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPP 462
Query: 430 PALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEG 489
A PE LP L PE ++PLSP P S P+++ SP+ E
Sbjct: 463 EASRLSPPPEELPASPL----PEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEE- 517
Query: 490 APVIPPSSGLPLPTPDARVG----ASTCGPP---DHLLPP---LGTPLPPD 530
+P+ PP P P + + AS PP L PP L T PP+
Sbjct: 518 SPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPE 568
Score = 40.0 bits (92), Expect = 0.007
Identities = 48/161 (29%), Positives = 62/161 (38%), Gaps = 34/161 (21%)
Query: 380 PATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALASPGSPE 439
PA EP P P LP EL L+P P ++ + PLP P + + +P
Sbjct: 898 PALSEPGEP-PLSPLPE---ELPLSPSGEPSLSPQLMPPD----PLPPPLSPIITAAAP- 948
Query: 440 PLPILSLNGGGPELAGDWGGAGDA-------------PLSPDPLLSSPPGSPKAALHSPV 486
P LS G EL +G GD+ P+SP P + P + P
Sbjct: 949 --PALSPLG---ELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPP 1003
Query: 487 SEGAPVIPPSSGLPLPTPDARVGASTCGP-PDHLLPPLGTP 526
S G+PV P S L P P C P H L P +P
Sbjct: 1004 SPGSPVGPASPILMEPLP------PQCSPLLQHSLVPQNSP 1038
Score = 39.7 bits (91), Expect = 0.009
Identities = 45/161 (27%), Positives = 59/161 (36%), Gaps = 19/161 (11%)
Query: 377 SYLPATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHS--PLHRSVSDLPLPLPQPALAS 434
S +PA+ + S + + PR S P P P S P R S P L
Sbjct: 2409 SRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHK 2468
Query: 435 PGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAP--- 491
P P+P PE+A G L ++ P P LH+ V G P
Sbjct: 2469 PPRPQP----------PEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNF 2518
Query: 492 VIPPSSG--LPLPTPDARVGASTCGPPDHLLPPLGTP-LPP 529
V P +G + P+P G P L PP+ P LPP
Sbjct: 2519 VRSPGTGAFVGTPSPMRFTFPQAVGEPS-LKPPVPQPGLPP 2558
Score = 35.8 bits (81), Expect = 0.13
Identities = 51/177 (28%), Positives = 63/177 (35%), Gaps = 38/177 (21%)
Query: 380 PATVEP---ASPTPAHSLPRAKSELTLTPDPAP----PMAHSPLHRSVSDLPLPLPQPAL 432
P EP A P H P+A+ L+P P P P V + P PQP
Sbjct: 772 PQPEEPCLCAVPEEPHLSPQAEGP-HLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEE 830
Query: 433 A--SPGSPEPL-----------------PILSLNGGGPELAGDWGGAGDAPLSPDPLLSS 473
+ SP S EP P+ PE G + PL P
Sbjct: 831 SHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFP------ 884
Query: 474 PPGSPKAA-LHSPVSEGAPVIPPSSGLPLPTPDARVGASTCGPPDHLLPPLGTPLPP 529
PPG P + L + P PP S LP P + G + P L+PP PLPP
Sbjct: 885 PPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSP--QLMPP--DPLPP 937
Score = 35.0 bits (79), Expect = 0.22
Identities = 43/143 (30%), Positives = 55/143 (38%), Gaps = 23/143 (16%)
Query: 385 PASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEPLPIL 444
P TP P A P+P PPM P S P+ P L P P+ P+L
Sbjct: 976 PILETPISPPPEANCT---DPEPVPPMILPPSPGS----PVGPASPILMEPLPPQCSPLL 1028
Query: 445 SLNGGGPELAGDWGGAGDAPLS-PDPLLSSPPG-----SPKAALHSPVSEGA-----PVI 493
+ PLS P PL SP G S +A LH +E P +
Sbjct: 1029 QHSLVPQNSPPSQCSPPALPLSVPSPL--SPIGKVVGVSDEAELHEMETEKVSEPECPAL 1086
Query: 494 PPSSGLPLPTPDARVGASTCGPP 516
PS+ PLP+P +G +C P
Sbjct: 1087 EPSATSPLPSP---MGDLSCPAP 1106
Score = 34.7 bits (78), Expect = 0.28
Identities = 37/119 (31%), Positives = 50/119 (42%), Gaps = 6/119 (5%)
Query: 380 PATVEPASPTP-AHSLPRAKSELTLTPDPAP-PMAHSPLHRSVSDLPLP--LPQPALASP 435
P P SP P A L + ++P P PM+ P +S LP+ L P SP
Sbjct: 611 PPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESP 670
Query: 436 GSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIP 494
SP P S PE + D+P SP P S P+ +L S E +P++P
Sbjct: 671 LSPPPEE--SPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLP 727
Score = 34.7 bits (78), Expect = 0.28
Identities = 33/104 (31%), Positives = 41/104 (39%), Gaps = 21/104 (20%)
Query: 404 TPDPAPPMAHSPLHRSVSDL------------PLPLPQPALASPGSPEPLPILSLNGGGP 451
+P P PP HS + +VS+L P P P P SP SP P++
Sbjct: 4883 SPAPEPPTQHSYTY-NVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLV------- 4934
Query: 452 ELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIPP 495
EL + P SP PL SSP + P EG PP
Sbjct: 4935 ELPTEPLAEPPVP-SPLPLASSPESARPKPRARPPEEGEDSRPP 4977
Score = 31.2 bits (69), Expect = 3.1
Identities = 38/121 (31%), Positives = 50/121 (41%), Gaps = 15/121 (12%)
Query: 383 VEPASPTPAHSLPRAKSEL---TLTPDPAPPMAHSPLHRSVSDLPLPLPQPALASPGSPE 439
V PASP LP S L +L P +PP SP LPL +P SP SP
Sbjct: 1009 VGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSP-----PALPLSVP-----SPLSPI 1058
Query: 440 PLPI-LSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIPPSSG 498
+ +S E+ + + P + +P +SP SP L P AP + SG
Sbjct: 1059 GKVVGVSDEAELHEMETEKVSEPECP-ALEPSATSPLPSPMGDLSCPAPSPAPALDDFSG 1117
Query: 499 L 499
L
Sbjct: 1118 L 1118
Score = 30.8 bits (68), Expect = 4.1
Identities = 44/175 (25%), Positives = 58/175 (33%), Gaps = 16/175 (9%)
Query: 407 PAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWG----GAGD 462
P P + L ++ + LP P PG P + L + G G G G
Sbjct: 2841 PGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGP 2900
Query: 463 A------PLSPDPLLSSPPGSPKAALHS--PVSEGAPVIPPSSGLPLPTPDARVGASTCG 514
P+S DP +P G A+ P AP P + PTP + G
Sbjct: 2901 PQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTG 2960
Query: 515 PPDHLLPPLGTPL-PPDWVTLEGDFVLMLAISPSHLGADLVAAPHARFDDGLVHL 568
PP T L P+ + LE L L D A D+ L HL
Sbjct: 2961 LELVNRPPSSTELGRPNPLALEAG---KLPCEDPELDDDFDAHKALEDDEELAHL 3012
Score = 29.6 bits (65), Expect = 9.2
Identities = 27/86 (31%), Positives = 34/86 (39%), Gaps = 14/86 (16%)
Query: 426 PLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSS----PPGSPKAA 481
P +P + PG P P I S G GP L P S + +++ P GSP
Sbjct: 2545 PSLKPPVPQPGLPPPHGINSHFGPGPTLG--------KPQSTNYTVATGNFHPSGSPLGP 2596
Query: 482 LHSPVSE--GAPVIPPSSGLPLPTPD 505
E G + P S LP P PD
Sbjct: 2597 SSGSTGESYGLSPLRPPSVLPPPAPD 2622
>gi|71896723 ceramide kinase-like isoform b [Homo sapiens]
Length = 558
Score = 52.4 bits (124), Expect = 1e-06
Identities = 58/240 (24%), Positives = 97/240 (40%), Gaps = 48/240 (20%)
Query: 179 RPPRLLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELVQGLSLSEW 238
RP L +L+NP + A Q V P++ AG+ ++ E + HA L++ L +
Sbjct: 165 RPKSLKILLNPQSHKKEATQVYYEKVEPLLKLAGIKTDVTIMEYEGHALSLLKECELQGF 224
Query: 239 DG--------------------------IVTVSGDGLLHEVLNGLL-----------DRP 261
DG +V V GDG EV + LL DR
Sbjct: 225 DGGHRKPLFAIHWSVQRLFTGMQTLEPSVVCVGGDGSASEVAHALLLRAQKNAGMETDRI 284
Query: 262 DWEEAVKMPVGILPCGSGNALAGAVNQHGGFEPALGLDLLLNCSLLLCRGGGHPLDLLSV 321
++P+G++P GS N LA +++ G+ ++ +L + G +D+ +
Sbjct: 285 LTPVRAQLPLGLIPAGSTNVLAHSLH---------GVPHVITATLHIIMGHVQLVDVCTF 335
Query: 322 TLASGSRCFSFLSVAWGFVSDVDIQSERFRALG-SARFTLGTVLGLATLHTYRGRLSYLP 380
+ A F F S +GF +E++R + + R V LA L +S+LP
Sbjct: 336 STAGKLLRFGF-SAMFGFGGRTLALAEKYRWMSPNQRRDFAVVKALAKLKAEDCEISFLP 394
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 52.4 bits (124), Expect = 1e-06
Identities = 53/187 (28%), Positives = 66/187 (35%), Gaps = 42/187 (22%)
Query: 386 ASPTPAHSLPRAKSELTLTPD---PAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEPLP 442
A TPA + P K L P P P A P + L P P+ A +P + P P
Sbjct: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG--GLATPPPKGAPTTPAATPPSP 1182
Query: 443 ILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIP------PS 496
L P+ AP +P ++ P SPK L +P +GAP P P
Sbjct: 1183 KGGLATPSPK---------GAPTTP----AATPPSPKGGLATPSPKGAPTTPAATPPSPK 1229
Query: 497 SGLPLPTPDARVGASTCGPPD-----HLLPPLGTPLPPDWVTLEGDFVLMLAISPSHLGA 551
GL P+P PP PP G P PP A +P L
Sbjct: 1230 GGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPP-------------AATPPSLKG 1276
Query: 552 DLVAAPH 558
L PH
Sbjct: 1277 GLATPPH 1283
Score = 50.8 bits (120), Expect = 4e-06
Identities = 46/153 (30%), Positives = 58/153 (37%), Gaps = 14/153 (9%)
Query: 385 PASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEPLPIL 444
P SP A LP + D +P HSP S P P P+ +P SP+ + +
Sbjct: 827 PVSPVEASFLPENSLSFQGSKD-SPATTHSPTPPS----PKGAPTPSAVTPLSPKGVTLP 881
Query: 445 SLNGGGPELAG----DWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIPPSSGLP 500
P + G A AP P LS SPK A +P +G P P G P
Sbjct: 882 PKETPTPSVVNLPFPKEGPATPAPKQA-PALSMTSSSPKKARATPAPKGIPASPSPKGAP 940
Query: 501 LP----TPDARVGASTCGPPDHLLPPLGTPLPP 529
P P + G +T P PP TP P
Sbjct: 941 TPPAATPPSPKGGPATPSPKWAPTPPAATPPSP 973
Score = 50.1 bits (118), Expect = 7e-06
Identities = 51/161 (31%), Positives = 67/161 (41%), Gaps = 32/161 (19%)
Query: 381 ATVEP--ASPTPAHSLPRAKSELTLTPD---PAPPMAHSPLHRSVSDLP--LPLPQPALA 433
AT P A TPA + P K P P PP A P + P P PA+
Sbjct: 1233 ATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV 1292
Query: 434 SPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAP-- 491
+P SP+ GGP + G +P P ++PP SPK + +P +GAP
Sbjct: 1293 TPPSPK---------GGPATSPPKG-------APTPPAATPP-SPKGSPGTPPPKGAPTP 1335
Query: 492 --VIPPSSG----LPLPTPDARVGASTCGPPDHLLPPLGTP 526
V PPS LP TP ++ G +T + PP TP
Sbjct: 1336 PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATP 1376
Score = 49.7 bits (117), Expect = 9e-06
Identities = 54/187 (28%), Positives = 67/187 (35%), Gaps = 39/187 (20%)
Query: 379 LPATVEP-ASPTPAHSLPRAKSELTLTPDP----APPMAHSPLHRSVSDLPLP--LPQPA 431
+PA+ P +PTP + P + TP P PP A P + P P P P
Sbjct: 930 IPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPP 989
Query: 432 LASPGSPEPLPIL-SLNG-------------GGPELAGDWGGAGDAPLSPDPLLSSPPGS 477
A+P SP+ P S G G P GA P + P SP GS
Sbjct: 990 AATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPP---SPKGS 1046
Query: 478 PKA-----------ALHSPVSEGAPVIPPSSGLPLP----TPDARVGASTCGPPDHLLPP 522
P A A P +G P P G P P P + G +T P +PP
Sbjct: 1047 PAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP 1106
Query: 523 LGTPLPP 529
TP P
Sbjct: 1107 AATPPSP 1113
Score = 48.5 bits (114), Expect = 2e-05
Identities = 47/160 (29%), Positives = 60/160 (37%), Gaps = 18/160 (11%)
Query: 386 ASPTPAHSLPRAK---SELTLTPDPAPPMAHSPLHRSVSDLPLP--LPQPALASPGSPEP 440
A TPA +LP K + +L P PP A P + P P P P A+P SP+
Sbjct: 1056 APTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKG 1115
Query: 441 LPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSP------PGSPKAALHSPVSEGAPVIP 494
+ G P + L+ P +P P SPK L +P +GAP P
Sbjct: 1116 GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175
Query: 495 ------PSSGLPLPTPDARVGASTCGPPDHLLPPLGTPLP 528
P GL P+P PP L TP P
Sbjct: 1176 AATPPSPKGGLATPSPKGAPTTPAATPPSP-KGGLATPSP 1214
Score = 44.3 bits (103), Expect = 4e-04
Identities = 51/164 (31%), Positives = 64/164 (39%), Gaps = 20/164 (12%)
Query: 380 PATVEP-ASPTPAHSLPRAKSELTLTPDP--AP-PMAHSPLHRSVSDLPLPLPQ----PA 431
PAT P +PTP + P + TP P AP P A +P S P P+ P
Sbjct: 977 PATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPP 1036
Query: 432 LASPGSPEPLPILS-LNGGGPEL-AGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEG 489
A+P SP+ P + L G P A P +P L P P A SP +G
Sbjct: 1037 AATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPS--LKGAPTPPAATPPSP--KG 1092
Query: 490 APVIPPSSGLPLP----TPDARVGASTCGPPDHLLPPLGTPLPP 529
P P G P+P P + G +T PP P PP
Sbjct: 1093 GPATPSPKGAPMPPAATPPSPKGGLAT--PPHKGAPTTPAATPP 1134
Score = 39.7 bits (91), Expect = 0.009
Identities = 45/153 (29%), Positives = 60/153 (39%), Gaps = 16/153 (10%)
Query: 380 PATVE-PASPTPAHSLPRAKSELTLTPDPAP--PMAHSPLHRSVSDLPLPLPQPALASPG 436
P T E A+P+ P A + ++L PA P S D LP P SP
Sbjct: 1419 PVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPP--SPK 1476
Query: 437 SPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIPPS 496
P P P P+ A A AP+ L + P SPK +P S P+ P +
Sbjct: 1477 EP-PAPKQVATSSSPKKAP----ATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTA 1531
Query: 497 SGLPLPTPDARVGASTCGPPDHLLPPLGTPLPP 529
+ L TP +T P + L+PP T P
Sbjct: 1532 TLLSKKTP------ATLAPKEALIPPAMTVPSP 1558
Score = 38.9 bits (89), Expect = 0.015
Identities = 48/159 (30%), Positives = 57/159 (35%), Gaps = 27/159 (16%)
Query: 381 ATVEPASP-TPAHSLPRAKSELTLTPDP-APPMAHSPLHRSVSDLPLPLPQPALASPGSP 438
ATV AS PA P A E+ + P P + P+ +P + PQ +S SP
Sbjct: 1663 ATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKG--------PQTKKSSATSP 1714
Query: 439 EPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIPPSSG 498
P S G G APL P SS K A HSP P+ PP S
Sbjct: 1715 PICPDPSAKNGSK---GPLSTVAPAPLLPVQKDSSKTAKGKDASHSPK---GPLAPPESK 1768
Query: 499 LPLPTPDARV--------GASTCGPPDHLLPPLGTPLPP 529
P A AS P PP+ PL P
Sbjct: 1769 ASTPLTAAAFEKVLPKPESASVSAAPS---PPVSLPLAP 1804
Score = 38.1 bits (87), Expect = 0.026
Identities = 42/156 (26%), Positives = 58/156 (37%), Gaps = 30/156 (19%)
Query: 387 SPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEPLPIL-- 444
SP + P +K+ LT + P SVS P P ++ P +P P+P L
Sbjct: 1757 SPKGPLAPPESKASTPLTAAAFEKVLPKPESASVS----AAPSPPVSLPLAPSPVPTLPP 1812
Query: 445 --SLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPV--------IP 494
P L + AP D LL P P +S G P P
Sbjct: 1813 KQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEP-------ISGGVPFQSVLVNMPTP 1865
Query: 495 PSSGLPLPTPDAR-------VGASTCGPPDHLLPPL 523
S+G+P+PTP A+ G+ T D +P L
Sbjct: 1866 KSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPEL 1901
Score = 36.2 bits (82), Expect = 0.098
Identities = 45/177 (25%), Positives = 58/177 (32%), Gaps = 26/177 (14%)
Query: 380 PATVEP-ASPTPAHSLPRAKSELTLTPDP----APPMAHSPLHRSVSDLPLPLPQP---- 430
PAT P +PTP + P + TP P PP P + LP P
Sbjct: 1301 PATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGP 1360
Query: 431 -ALASPGSPEPLPILSLNGGGPELA--------------GDWGGAGDAPLSPDPLLSSPP 475
+S P P + GGP + GD PLSP ++P
Sbjct: 1361 TTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPV 1420
Query: 476 GSPKAALHSPVSEGAPVIPPSSGLPLPTPDARVG--ASTCGPPDHLLPPLGTPLPPD 530
AA S P + P S P A G A+ D LP + P P +
Sbjct: 1421 TREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE 1477
Score = 35.0 bits (79), Expect = 0.22
Identities = 40/144 (27%), Positives = 54/144 (37%), Gaps = 16/144 (11%)
Query: 385 PASPT-------PAHSLPRAKSELTLTPDPA--PPMAHSPLHRSVSDLPLPLPQPALASP 435
PA+P+ P +L K+ TL P A PP P + +P P PA S
Sbjct: 1517 PATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSS 1576
Query: 436 --GSPEPLPILSLNGGGP---ELAGDWGGAGDAPL-SPDPLLSSPPGSPKAALHSPVSEG 489
S P S G P EL +P +P P +PP SP+ +P +G
Sbjct: 1577 KEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPP-SPEKGPATPAPKG 1635
Query: 490 APVIPPSSGLPLPTPDARVGASTC 513
P PP + L + TC
Sbjct: 1636 TPTSPPVTPSSLKDSPTSPASVTC 1659
Score = 34.7 bits (78), Expect = 0.28
Identities = 36/118 (30%), Positives = 51/118 (43%), Gaps = 15/118 (12%)
Query: 376 LSYLPATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLP-LPL-PQPALA 433
L +PA++E A +PA + K + T+ P +SP +S S P +PL P+ LA
Sbjct: 532 LQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLA 591
Query: 434 SPGSPEPLPI----------LSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAA 481
EPLPI L +N + D + P S PLL S +P A
Sbjct: 592 KKSLGEPLPIGKPASSMTSPLGVNSSASVIKTD---SYAGPDSAGPLLKSSLITPTVA 646
Score = 34.7 bits (78), Expect = 0.28
Identities = 39/150 (26%), Positives = 56/150 (37%), Gaps = 19/150 (12%)
Query: 362 TVLGLATLHTYRGRLSYLPATVEPASPTPAHSLPRAKSELTLTPDP----APPMAHSPLH 417
T+L T T + + +P + SP ++P K E TP +PP +
Sbjct: 1532 TLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPK-EAPATPSSKEASSPPAVTPSTY 1590
Query: 418 RSVSDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGS 477
+ L PA+ SP E ++ PE G A +P +SPP +
Sbjct: 1591 KGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPE-------KGPATPAPKGTPTSPPVT 1643
Query: 478 PKAALHSPVSE-------GAPVIPPSSGLP 500
P + SP S GA V S GLP
Sbjct: 1644 PSSLKDSPTSPASVTCKMGATVPQASKGLP 1673
Score = 32.0 bits (71), Expect = 1.8
Identities = 46/176 (26%), Positives = 64/176 (36%), Gaps = 38/176 (21%)
Query: 380 PATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLH----RSVSDLPLPLPQPALASP 435
P P SP P A ++ + P P+ +A +PL +S S LPL A
Sbjct: 43 PTLPPPCSPAPQQCPLSAANQASPFPSPST-IASTPLEVPFPQSSSGTALPLGTAPEAPT 101
Query: 436 GSPE----PLPILSLNGGGPELAGDWGG--AGDAPLS---------------PDPLLSSP 474
P P+ +L P +A G + APL+ P LL+SP
Sbjct: 102 FLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSP 161
Query: 475 PGSPKAALHSPVSEGAPVIPPSSGLPLPTPDARVGASTCGPPDHLLP-PLGTPLPP 529
P A S ++ AP+ P L P ++P P GTP PP
Sbjct: 162 PSVAVAESGSVITLSAPIAPSEPKTNLNK-----------VPSEVVPNPKGTPSPP 206
Score = 31.6 bits (70), Expect = 2.4
Identities = 49/180 (27%), Positives = 73/180 (40%), Gaps = 22/180 (12%)
Query: 374 GRLSYLPATVEPASPTPAHSLPRAKSELTLTPD--PAPPMAHS--PLHRSVSDLPLPLPQ 429
G + L A + P+ P +L + SE+ P P+PP S P H P+ Q
Sbjct: 170 GSVITLSAPIAPSEPKT--NLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVT---PMASIQ 224
Query: 430 PALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEG 489
+AS P+ P +L P++ D +S +L SP +L PVS
Sbjct: 225 SGVAS--LPQTTPTTTLAIASPQVK-------DTTISS--VLISPQNPGSLSLKGPVSPP 273
Query: 490 APVIPPSSGLPLPTPDARVGASTCGPPDHLLPPLGTPLPPDWVTLEGDFVLMLAISPSHL 549
A + + LP+ T + A PPD + LG+ L P + G L+ PS L
Sbjct: 274 AALSLSTQSLPVVTSSQKT-AGPNTPPDFPI-SLGSHLAPLHQSSFGSVQLLGQTGPSAL 331
Score = 30.8 bits (68), Expect = 4.1
Identities = 31/132 (23%), Positives = 54/132 (40%), Gaps = 9/132 (6%)
Query: 380 PATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALASPGSPE 439
P+T+ + +P+ SL A S +L+P + + SP + PL P + +P
Sbjct: 385 PSTISSITCSPSGSLNVATS-FSLSPTTSLILKSSP--NATYHYPLVAQMPVSSVGTTPL 441
Query: 440 PLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIPPSSGL 499
+ P + P+S P+ + P SP A + +PV+ P ++ L
Sbjct: 442 VVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTL 501
Query: 500 ------PLPTPD 505
PLP P+
Sbjct: 502 RIPVSPPLPDPE 513
>gi|239508790 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 490
Score = 51.2 bits (121), Expect = 3e-06
Identities = 54/172 (31%), Positives = 72/172 (41%), Gaps = 15/172 (8%)
Query: 377 SYLPATVEPAS--PTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSV----SDLP-LPLPQ 429
S L P S P+P +P S++ L D P + PL V SD+P LP
Sbjct: 179 SLLSGVPSPPSDVPSPPSDVPSPPSDVPLLSDVPSPPSDVPLLSDVPSPPSDVPSLPSDV 238
Query: 430 PALASPGSPEPLPILSLNGGGPELAGDWGGAGDAP--LSPDPLLSSPPGSPKAALHSPVS 487
P+L+ SP P + SL G P D D P LS P L S S + + SP S
Sbjct: 239 PSLSGVPSP-PSDVPSLLSGVPSPPSDISPPSDVPSLLSDVPSLPSDVPSLLSGVPSPPS 297
Query: 488 EGAPVIP----PSSGLPLPTPDARVGASTCGPPDHL-LPPLGTPLPPDWVTL 534
+ ++ P S +P P D + + PP + PP P PP V L
Sbjct: 298 DVPSLLSDVPSPPSDVPSPPSDIPLLSGVPSPPSDVPSPPSDVPSPPSDVPL 349
Score = 42.4 bits (98), Expect = 0.001
Identities = 43/155 (27%), Positives = 58/155 (37%), Gaps = 15/155 (9%)
Query: 379 LPATVEPAS--PTPAHSLPRAKSELTLTP-DPAPPMAHSPLHRSVSDLPLPLPQPALASP 435
LP+ V S P+P +P S + P D +PP L V LP +P P
Sbjct: 234 LPSDVPSLSGVPSPPSDVPSLLSGVPSPPSDISPPSDVPSLLSDVPSLPSDVPSLLSGVP 293
Query: 436 GSPEPLPILSLNGGGPELAGDWGGAGDAPLSPD--PLLSSPPGSPKAALHSPVSEGAPV- 492
P +P L + P D P P PLLS P P P +P
Sbjct: 294 SPPSDVPSLLSDVPSPP--------SDVPSPPSDIPLLSGVPSPPSDVPSPPSDVPSPPS 345
Query: 493 -IPPSSGLPLPTPDARVGASTCGPPDHLLPPLGTP 526
+P SG+P P D + + PP + L +P
Sbjct: 346 DVPLLSGVPSPLSDVPLLSGVPSPPSDVPSLLMSP 380
Score = 41.2 bits (95), Expect = 0.003
Identities = 58/189 (30%), Positives = 72/189 (38%), Gaps = 39/189 (20%)
Query: 385 PASP-----TPAHSLPRAKSELTLTPDPAPPMAHSPL---HRSVSDLPLPLPQPALASPG 436
P SP +P H L L ++P +P H PL H S+ PL P L+
Sbjct: 57 PVSPHFPLVSPHHPLMSPHYSL-VSPQYSPVSPHCPLVSPHYSLVSPHRPLVSPLLSGVP 115
Query: 437 SPEPLPILSLNGGGPELAGDWGGA-GDAP--LSPDPLLSSPPGSPKAALHSPVSE----- 488
SP P + SL G P L D D P LS P L S SP + + SP S+
Sbjct: 116 SP-PSDVPSLLSGVPSLPSDVSSPPSDVPSLLSDVPSLLSGVPSPPSDVPSPPSDVPSPP 174
Query: 489 --------GAPVIP-----PSSGLPLPTPDARVGASTCGPP-------DHLLPPLGTP-L 527
G P P P S +P P D + + PP D PP P L
Sbjct: 175 SDVPSLLSGVPSPPSDVPSPPSDVPSPPSDVPLLSDVPSPPSDVPLLSDVPSPPSDVPSL 234
Query: 528 PPDWVTLEG 536
P D +L G
Sbjct: 235 PSDVPSLSG 243
Score = 37.7 bits (86), Expect = 0.034
Identities = 40/153 (26%), Positives = 54/153 (35%), Gaps = 39/153 (25%)
Query: 388 PTPAHSLPRAKSELTLTPDPAP-PMAHSPLHRSVSDLPLPLPQPALASPGSPEPLPILS- 445
P+P +P S++ P P P + PL V P +P P P P +P+LS
Sbjct: 293 PSPPSDVPSLLSDVPSPPSDVPSPPSDIPLLSGVPSPPSDVPSPPSDVPSPPSDVPLLSG 352
Query: 446 ---LNGGGPELAGDWGGAGDAP---LSPDPLL---------------------------- 471
P L+G D P +SP LL
Sbjct: 353 VPSPLSDVPLLSGVPSPPSDVPSLLMSPHRLLMSHYSLVSPHRLDVPSLLSDVPSLLSGV 412
Query: 472 -SSPPGSPKAALHSPVSEGAPVIPPSSGLPLPT 503
SSP G P P+ G P +P SG+P P+
Sbjct: 413 PSSPSGVPSLPSGVPILSGVPSLP--SGVPSPS 443
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 51.2 bits (121), Expect = 3e-06
Identities = 46/159 (28%), Positives = 62/159 (38%), Gaps = 21/159 (13%)
Query: 378 YLPATVEPASPTPAHSLPRAKSELTLTPDPA--PPMAHSPLHRSVSDLPLPLPQPALASP 435
Y P + P SP P S PR + E + P P+ P H+P+ P + A P
Sbjct: 159 YHPPPLFPPSPQPPDSTPR-QPEASFEPHPSVTPTGYHAPMEP-------PTSRMFQAPP 210
Query: 436 GSPEPLPILSLNG-----GGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGA 490
G+P P P L G GP + GGA + P+ PP + ++ S + GA
Sbjct: 211 GAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGA 270
Query: 491 PVIPPSSGLPLPTPDARVGASTCGPPDHLLPPLGTPLPP 529
P P PT G PP P + LPP
Sbjct: 271 PPTKP------PTTPVGGGNLPSAPPPANFPHVTPNLPP 303
Score = 34.7 bits (78), Expect = 0.28
Identities = 39/168 (23%), Positives = 61/168 (36%), Gaps = 15/168 (8%)
Query: 365 GLATLHTYRGRLSYLPATVEPASPTPAHSLPRAKSELTLTP-----DPAPPMAHSPLHRS 419
G ++ H + +S ++ P P PAH LP S+++ + P ++S S
Sbjct: 521 GGSSHHAHPYAMSPSLGSLRPYPPGPAH-LPPPHSQVSYSQAGPNGPPVSSSSNSSSSTS 579
Query: 420 VSDLPLPLPQPALASPGSPEPL-PILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSP 478
P P P+ G+P P P+ ++ L+ +P +SPPG P
Sbjct: 580 QGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYK--TASPPGPP 637
Query: 479 KAALHSPVSEGAPVIPPSSGLPLPTPDARVGASTCGPPDH--LLPPLG 524
+P P P P R G PP + PP G
Sbjct: 638 PYGKRAPSPGAYKTATPPGYKPGSPPSFRTGT----PPGYRGTSPPAG 681
Score = 30.0 bits (66), Expect = 7.0
Identities = 43/164 (26%), Positives = 52/164 (31%), Gaps = 26/164 (15%)
Query: 367 ATLHTYRGRLSYLPATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLP 426
ATL T ++ PA + ASP P P P +P S
Sbjct: 612 ATLSTVIATVASSPAGYKTASP----------------PGPPPYGKRAP-----SPGAYK 650
Query: 427 LPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPV 486
P PGSP G P G AG P P P A
Sbjct: 651 TATPPGYKPGSPPSFR----TGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLP 706
Query: 487 SEGAPVIPPSSGLPL-PTPDARVGASTCGPPDHLLPPLGTPLPP 529
S P P+SG PL T + A P+ +PP +P PP
Sbjct: 707 SLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPP 750
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 51.2 bits (121), Expect = 3e-06
Identities = 46/159 (28%), Positives = 62/159 (38%), Gaps = 21/159 (13%)
Query: 378 YLPATVEPASPTPAHSLPRAKSELTLTPDPA--PPMAHSPLHRSVSDLPLPLPQPALASP 435
Y P + P SP P S PR + E + P P+ P H+P+ P + A P
Sbjct: 159 YHPPPLFPPSPQPPDSTPR-QPEASFEPHPSVTPTGYHAPMEP-------PTSRMFQAPP 210
Query: 436 GSPEPLPILSLNG-----GGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGA 490
G+P P P L G GP + GGA + P+ PP + ++ S + GA
Sbjct: 211 GAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGA 270
Query: 491 PVIPPSSGLPLPTPDARVGASTCGPPDHLLPPLGTPLPP 529
P P PT G PP P + LPP
Sbjct: 271 PPTKP------PTTPVGGGNLPSAPPPANFPHVTPNLPP 303
Score = 34.7 bits (78), Expect = 0.28
Identities = 39/168 (23%), Positives = 61/168 (36%), Gaps = 15/168 (8%)
Query: 365 GLATLHTYRGRLSYLPATVEPASPTPAHSLPRAKSELTLTP-----DPAPPMAHSPLHRS 419
G ++ H + +S ++ P P PAH LP S+++ + P ++S S
Sbjct: 521 GGSSHHAHPYAMSPSLGSLRPYPPGPAH-LPPPHSQVSYSQAGPNGPPVSSSSNSSSSTS 579
Query: 420 VSDLPLPLPQPALASPGSPEPL-PILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSP 478
P P P+ G+P P P+ ++ L+ +P +SPPG P
Sbjct: 580 QGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYK--TASPPGPP 637
Query: 479 KAALHSPVSEGAPVIPPSSGLPLPTPDARVGASTCGPPDH--LLPPLG 524
+P P P P R G PP + PP G
Sbjct: 638 PYGKRAPSPGAYKTATPPGYKPGSPPSFRTGT----PPGYRGTSPPAG 681
Score = 30.0 bits (66), Expect = 7.0
Identities = 43/164 (26%), Positives = 52/164 (31%), Gaps = 26/164 (15%)
Query: 367 ATLHTYRGRLSYLPATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLP 426
ATL T ++ PA + ASP P P P +P S
Sbjct: 612 ATLSTVIATVASSPAGYKTASP----------------PGPPPYGKRAP-----SPGAYK 650
Query: 427 LPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPV 486
P PGSP G P G AG P P P A
Sbjct: 651 TATPPGYKPGSPPSFR----TGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLP 706
Query: 487 SEGAPVIPPSSGLPL-PTPDARVGASTCGPPDHLLPPLGTPLPP 529
S P P+SG PL T + A P+ +PP +P PP
Sbjct: 707 SLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPP 750
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 50.1 bits (118), Expect = 7e-06
Identities = 47/143 (32%), Positives = 56/143 (39%), Gaps = 16/143 (11%)
Query: 367 ATLHTYRGRLSYLPATVEPASPTPAHSLP----RAKSELTLTPDPAPPMAHSPLHRSVSD 422
++L RG L+ LP PAS P P A P PAPP P
Sbjct: 737 SSLRAERGSLADLPMA-PPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADP 795
Query: 423 LPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAAL 482
P P A+ASPGS L+ GP+ GD G + P SP+ + PG A
Sbjct: 796 AASPDPPSAVASPGS-------GLSSPGPK-PGDSGYETETPFSPE---GAFPGGGAAEE 844
Query: 483 HSPVSEGAPVIPPSSGLPLPTPD 505
AP PP G P P PD
Sbjct: 845 EGVPRPRAPPEPPDPGAPRPPPD 867
Score = 37.0 bits (84), Expect = 0.057
Identities = 46/154 (29%), Positives = 57/154 (37%), Gaps = 13/154 (8%)
Query: 385 PASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRS-VSDLPL-PLPQPALASPGSPEPLP 442
P S PA ++ E +L PAP S + + PL P P+ PG+ P
Sbjct: 1063 PESWGPAPTIGEPAPETSLERAPAPSAVVSSRNGGETAPGPLGPAPKNGTLEPGTERRAP 1122
Query: 443 ILSLNGGGPELAG----DWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIPPSSG 498
GG P G D G G AP+ PGS A V P PP
Sbjct: 1123 E---TGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNTRPQ-PPPPP 1178
Query: 499 LPLPTPDARVGASTCGPPDHL--LPPLGTPLPPD 530
LP P P+A+ PP + P G P PD
Sbjct: 1179 LP-PPPEAQPRRLEPAPPRARPEVAPEGEPGAPD 1211
Score = 35.0 bits (79), Expect = 0.22
Identities = 40/142 (28%), Positives = 47/142 (33%), Gaps = 31/142 (21%)
Query: 407 PAPPMAHSPLHRSVSDLP-LPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPL 465
P PP S L L LP+ PA A P +PL + P+ G
Sbjct: 730 PHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPL----MGAAAPQYPGR--------- 776
Query: 466 SPDPLLSSPPGSPKAALHSPVSEGAP--VIPPSSGLPLPTP---DARVGASTCGPPDHLL 520
P P PP P+A S P V P SGL P P D+ T P+
Sbjct: 777 GPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAF 836
Query: 521 P------------PLGTPLPPD 530
P P P PPD
Sbjct: 837 PGGGAAEEEGVPRPRAPPEPPD 858
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 49.7 bits (117), Expect = 9e-06
Identities = 46/168 (27%), Positives = 64/168 (38%), Gaps = 28/168 (16%)
Query: 371 TYRGRLSYLPAT---------VEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVS 421
+Y+G +SY A PA P P A + P PAPP +P+ +
Sbjct: 86 SYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAA- 144
Query: 422 DLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAA 481
P P+ A A+ +P P P + G + A AP +P + +PP P+ A
Sbjct: 145 --PARAPRAAAAAATAP-PSPGPAQPGPRAQRAAPLAAPPPAPAAPPAV--APPAGPRRA 199
Query: 482 LHSPVSEGAPVIPPSSGLPLPTPDARVGASTCGPPDHLLPPLGTPLPP 529
V+ P +PP P P A PP PP P PP
Sbjct: 200 PPPAVAAREPPLPPP-----PQPPA--------PPQQQQPPPPQPQPP 234
Score = 35.0 bits (79), Expect = 0.22
Identities = 36/118 (30%), Positives = 42/118 (35%), Gaps = 34/118 (28%)
Query: 381 ATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEP 440
A P SP PA PRA+ A P+A P P P PA+A P P
Sbjct: 155 AATAPPSPGPAQPGPRAQR--------AAPLAAPP--------PAPAAPPAVAPPAGPRR 198
Query: 441 LPILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPGSPKAALHSPVSEGAPVIPPSSG 498
P P +A A + PL P P PP P+ P P PP G
Sbjct: 199 AP-------PPAVA-----AREPPLPPPP---QPPAPPQQQQPPPPQ---PQPPPEGG 238
>gi|239750506 PREDICTED: hypothetical protein XP_002347417 [Homo
sapiens]
Length = 325
Score = 49.3 bits (116), Expect = 1e-05
Identities = 52/187 (27%), Positives = 68/187 (36%), Gaps = 30/187 (16%)
Query: 361 GTVLGLATLHTYRGRLSYLPATVEPASPTPAHSLPRAKSELTLTPDPA--PPMAHSPLHR 418
G V G H+ R R +++PA +P P H+ PR + L+ TP PP + PLH
Sbjct: 14 GDVRGSERRHSTRTRKTHVPA-----NPAPFHT-PRKRHPLSHTPHATAHPPSSPPPLHI 67
Query: 419 SVSDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPD---------- 468
+ P+ P P L + +G G + G A PL P
Sbjct: 68 T------PVLPPTFPGTQPPRALRLAEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGP 121
Query: 469 ------PLLSSPPGSPKAALHSPVSEGAPVIPPSSGLPLPTPDARVGASTCGPPDHLLPP 522
SS PG P AA P + P S P A G+ P LL P
Sbjct: 122 CSAPVGSRASSGPGLPSAAAARPARKTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGP 181
Query: 523 LGTPLPP 529
G P P
Sbjct: 182 GGRPSSP 188
>gi|239744803 PREDICTED: hypothetical protein XP_002343287 [Homo
sapiens]
Length = 325
Score = 49.3 bits (116), Expect = 1e-05
Identities = 52/187 (27%), Positives = 68/187 (36%), Gaps = 30/187 (16%)
Query: 361 GTVLGLATLHTYRGRLSYLPATVEPASPTPAHSLPRAKSELTLTPDPA--PPMAHSPLHR 418
G V G H+ R R +++PA +P P H+ PR + L+ TP PP + PLH
Sbjct: 14 GDVRGSERRHSTRTRKTHVPA-----NPAPFHT-PRKRHPLSHTPHATAHPPSSPPPLHI 67
Query: 419 SVSDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPD---------- 468
+ P+ P P L + +G G + G A PL P
Sbjct: 68 T------PVLPPTFPGTQPPRALRLAEGSGEGKQEEGRRAQARPRPLRPPWEVRGGARGP 121
Query: 469 ------PLLSSPPGSPKAALHSPVSEGAPVIPPSSGLPLPTPDARVGASTCGPPDHLLPP 522
SS PG P AA P + P S P A G+ P LL P
Sbjct: 122 CSAPVGSRASSGPGLPSAAAARPARKTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGP 181
Query: 523 LGTPLPP 529
G P P
Sbjct: 182 GGRPSSP 188
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 49.3 bits (116), Expect = 1e-05
Identities = 58/197 (29%), Positives = 69/197 (35%), Gaps = 26/197 (13%)
Query: 352 ALGSARFTLGTVLGLATLHTYRGRLSYLPATVEPASPTPAHSLPRAKSELTLTPDPAPPM 411
A G A +G+ LG T R S L T +PTPA PR++S PP
Sbjct: 729 AEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPP- 787
Query: 412 AHSPLHRSVSDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLL 471
P P + + S SPEP P+ G G P P
Sbjct: 788 ------------PPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGP---- 831
Query: 472 SSPPGSPKAA-------LHSPVSEGAPVIPPSSGLPLPTPDARVGASTCGPPDHLLPPLG 524
S PPG P A P EG P SSG LP + P PP
Sbjct: 832 SEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRE 891
Query: 525 TPLPP--DWVTLEGDFV 539
TP+PP D+ E D V
Sbjct: 892 TPVPPGLDFNLTESDTV 908
Score = 43.5 bits (101), Expect = 6e-04
Identities = 39/138 (28%), Positives = 51/138 (36%), Gaps = 12/138 (8%)
Query: 383 VEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEPLP 442
V A+P PA LP TP +PP + P S +P P SP P+P
Sbjct: 929 VASATPGPAAPLPSP------TPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVP 982
Query: 443 ILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPG----SPKAALHSPVSEGAPVIPPSSG 498
G A W G + P +P LL P P + + ++ P + P G
Sbjct: 983 PCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLG 1042
Query: 499 LPLPTPDAR-VGASTCGP 515
P P P R T GP
Sbjct: 1043 -PRPVPPPRPESTGTVGP 1059
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 49.3 bits (116), Expect = 1e-05
Identities = 58/197 (29%), Positives = 69/197 (35%), Gaps = 26/197 (13%)
Query: 352 ALGSARFTLGTVLGLATLHTYRGRLSYLPATVEPASPTPAHSLPRAKSELTLTPDPAPPM 411
A G A +G+ LG T R S L T +PTPA PR++S PP
Sbjct: 811 AEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPP- 869
Query: 412 AHSPLHRSVSDLPLPLPQPALASPGSPEPLPILSLNGGGPELAGDWGGAGDAPLSPDPLL 471
P P + + S SPEP P+ G G P P
Sbjct: 870 ------------PPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGP---- 913
Query: 472 SSPPGSPKAA-------LHSPVSEGAPVIPPSSGLPLPTPDARVGASTCGPPDHLLPPLG 524
S PPG P A P EG P SSG LP + P PP
Sbjct: 914 SEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRE 973
Query: 525 TPLPP--DWVTLEGDFV 539
TP+PP D+ E D V
Sbjct: 974 TPVPPGLDFNLTESDTV 990
Score = 43.5 bits (101), Expect = 6e-04
Identities = 39/138 (28%), Positives = 51/138 (36%), Gaps = 12/138 (8%)
Query: 383 VEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALASPGSPEPLP 442
V A+P PA LP TP +PP + P S +P P SP P+P
Sbjct: 1011 VASATPGPAAPLPSP------TPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVP 1064
Query: 443 ILSLNGGGPELAGDWGGAGDAPLSPDPLLSSPPG----SPKAALHSPVSEGAPVIPPSSG 498
G A W G + P +P LL P P + + ++ P + P G
Sbjct: 1065 PCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLG 1124
Query: 499 LPLPTPDAR-VGASTCGP 515
P P P R T GP
Sbjct: 1125 -PRPVPPPRPESTGTVGP 1141
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.138 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,243,454
Number of Sequences: 37866
Number of extensions: 2134788
Number of successful extensions: 16114
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 1048
Number of HSP's that attempted gapping in prelim test: 11238
Number of HSP's gapped (non-prelim): 4710
length of query: 654
length of database: 18,247,518
effective HSP length: 109
effective length of query: 545
effective length of database: 14,120,124
effective search space: 7695467580
effective search space used: 7695467580
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.