Guide to the Human Genome
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Name: SPHK1 Sequence: fasta or formatted (384aa) NCBI GI: 217272883
Description:

sphingosine kinase 1 isoform 3

Referenced in:

Sphingomyelin, Ceramides, and Glycolipids

Other entries for this name:
alt prot [398aa] sphingosine kinase 1 isoform 1
alt prot [470aa] sphingosine kinase 1 isoform 2
alt mRNA [384aa] sphingosine kinase 1 isoform 3
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.1         31           2
 C cysteine            1.8          7           1
 D aspartate           3.1         12           1
 E glutamate           7.0         27           2
 F phenylalanine       3.4         13           1
 G glycine             8.1         31           2
 H histidine           3.1         12           1
 I isoleucine          0.8          3           1
 K lysine              2.3          9           1
 L leucine            14.8         57           3
 M methionine          4.2         16           1
 N asparagine          2.3          9           1
 P proline             8.1         31           3
 Q glutamine           2.6         10           2
 R arginine            7.3         28           2
 S serine              5.7         22           1
 T threonine           3.1         12           1
 V valine              9.9         38           3
 W tryptophan          1.6          6           1
 Y tyrosine            2.6         10           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   sphingosine kinase 1 isoform 3 
SPHK1                 1.000   sphingosine kinase 1 isoform 3 
SPHK1                 1.000   sphingosine kinase 1 isoform 2 
SPHK1                 0.991   sphingosine kinase 1 isoform 1 
SPHK2                 0.302   sphingosine kinase 2 
CERK                  0.091   ceramide kinase 
AGK                   0.077   acylglycerol kinase 
CERKL                 0.057   ceramide kinase-like isoform a 
CERKL                 0.038   ceramide kinase-like isoform b 
DGKI                  0.013   diacylglycerol kinase, iota 
ORAI3                 0.008   ORAI calcium release-activated calcium modulator 3 [...
CERKL                 0.007   ceramide kinase-like isoform d 
SF3B3                 0.007   splicing factor 3b, subunit 3 
LOC100133405          0.007   PREDICTED: hypothetical protein 
MTSS1                 0.007   metastasis suppressor 1 
LOC392145             0.005   hypothetical protein LOC392145 
NEURL4                0.005   neuralized homolog 4 isoform 1 
NEURL4                0.005   neuralized homolog 4 isoform 2 
DGKA                  0.005   diacylglycerol kinase, alpha 80kDa 
DGKA                  0.005   diacylglycerol kinase, alpha 80kDa 
DGKA                  0.005   diacylglycerol kinase, alpha 80kDa 
DGKA                  0.005   diacylglycerol kinase, alpha 80kDa 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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