Guide to the Human Genome
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Name: SPHK1 Sequence: fasta or formatted (470aa) NCBI GI: 217272880
Description:

sphingosine kinase 1 isoform 2

Referenced in:

Sphingomyelin, Ceramides, and Glycolipids

Other entries for this name:
alt prot [398aa] sphingosine kinase 1 isoform 1
alt prot [384aa] sphingosine kinase 1 isoform 3
alt prot [384aa] sphingosine kinase 1 isoform 3
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            10.4         49           3
 C cysteine            1.7          8           1
 D aspartate           3.2         15           1
 E glutamate           6.8         32           2
 F phenylalanine       3.0         14           1
 G glycine             8.9         42           2
 H histidine           2.8         13           1
 I isoleucine          0.6          3           1
 K lysine              2.3         11           1
 L leucine            13.4         63           3
 M methionine          3.6         17           1
 N asparagine          2.1         10           1
 P proline             9.1         43           3
 Q glutamine           2.6         12           2
 R arginine            7.2         34           2
 S serine              5.7         27           1
 T threonine           3.8         18           1
 V valine              8.7         41           3
 W tryptophan          1.7          8           1
 Y tyrosine            2.1         10           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   sphingosine kinase 1 isoform 2 
SPHK1                 0.811   sphingosine kinase 1 isoform 3 
SPHK1                 0.811   sphingosine kinase 1 isoform 3 
SPHK1                 0.804   sphingosine kinase 1 isoform 1 
SPHK2                 0.245   sphingosine kinase 2 
CERK                  0.074   ceramide kinase 
AGK                   0.062   acylglycerol kinase 
CERKL                 0.046   ceramide kinase-like isoform a 
CERKL                 0.031   ceramide kinase-like isoform b 
LMTK3                 0.015   lemur tyrosine kinase 3 
SAMD1                 0.015   sterile alpha motif domain containing 1 
PHOX2B                0.013   paired-like homeobox 2b 
DGKI                  0.013   diacylglycerol kinase, iota 
AGAP2                 0.012   centaurin, gamma 1 isoform PIKE-L 
HCN4                  0.012   hyperpolarization activated cyclic nucleotide-gated p...
LOC100292853          0.011   PREDICTED: hypothetical protein 
LOC100288412          0.011   PREDICTED: hypothetical protein XP_002342328 
LOC388199             0.011   PREDICTED: hypothetical protein LOC388199 
COL1A2                0.011   alpha 2 type I collagen 
LOC100293055          0.011   PREDICTED: similar to COL22A1 protein 
CDC42EP1              0.011   CDC42 effector protein 1 
GSPT1                 0.011   G1 to S phase transition 1 isoform 1 
DVL1                  0.010   dishevelled 1 
LOC100130884          0.010   PREDICTED: hypothetical protein 
LOC100292865          0.010   PREDICTED: hypothetical protein 
LOC100130884          0.010   PREDICTED: hypothetical protein 
LOC100130884          0.010   PREDICTED: hypothetical protein 
TXLNB                 0.010   taxilin beta 
PLCH2                 0.010   phospholipase C, eta 2 
LOC100287514          0.010   PREDICTED: hypothetical protein XP_002343754 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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