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Search of human proteins with 21361659
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361659 importin 9 [Homo sapiens]
(1041 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361659 importin 9 [Homo sapiens] 2053 0.0
gi|198041777 Ran binding protein 11 isoform 1 [Homo sapiens] 72 4e-12
gi|39725950 Ran binding protein 11 isoform 2 [Homo sapiens] 72 4e-12
gi|29029559 CSE1 chromosome segregation 1-like protein [Homo sap... 60 1e-08
gi|5453998 importin 7 [Homo sapiens] 59 3e-08
gi|53759103 importin 8 [Homo sapiens] 58 5e-08
gi|209969838 transportin 2 (importin 3, karyopherin beta 2b) iso... 47 7e-05
gi|209969836 transportin 2 (importin 3, karyopherin beta 2b) iso... 47 7e-05
gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isof... 47 7e-05
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 45 4e-04
gi|215422388 death-domain associated protein isoform a [Homo sap... 45 4e-04
gi|215422366 death-domain associated protein isoform b [Homo sap... 45 4e-04
gi|156071452 nardilysin isoform b [Homo sapiens] 44 8e-04
gi|156071450 nardilysin isoform a [Homo sapiens] 44 8e-04
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 41 0.005
gi|23510381 transportin 1 isoform 2 [Homo sapiens] 41 0.007
gi|133925811 transportin 1 isoform 1 [Homo sapiens] 41 0.007
gi|55956788 nucleolin [Homo sapiens] 40 0.011
gi|14249412 tripartite motif-containing 52 [Homo sapiens] 40 0.011
gi|239747212 PREDICTED: hypothetical protein XP_002346939 [Homo ... 39 0.020
gi|41349472 PR domain containing 16 isoform 2 [Homo sapiens] 39 0.020
gi|41349470 PR domain containing 16 isoform 1 [Homo sapiens] 39 0.020
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 39 0.020
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 39 0.020
gi|151101404 prothymosin, alpha isoform 2 [Homo sapiens] 38 0.057
gi|17975763 myelin transcription factor 1 [Homo sapiens] 37 0.074
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 37 0.074
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 37 0.074
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 37 0.074
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 37 0.097
>gi|21361659 importin 9 [Homo sapiens]
Length = 1041
Score = 2053 bits (5319), Expect = 0.0
Identities = 1041/1041 (100%), Positives = 1041/1041 (100%)
Query: 1 MAAAAAAGAASGLPGPVAQGLKEALVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHL 60
MAAAAAAGAASGLPGPVAQGLKEALVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHL
Sbjct: 1 MAAAAAAGAASGLPGPVAQGLKEALVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHL 60
Query: 61 AELTVDPQGALAIRQLASVILKQYVETHWCAQSEKFRPPETTERAKIVIRELLPNGLRES 120
AELTVDPQGALAIRQLASVILKQYVETHWCAQSEKFRPPETTERAKIVIRELLPNGLRES
Sbjct: 61 AELTVDPQGALAIRQLASVILKQYVETHWCAQSEKFRPPETTERAKIVIRELLPNGLRES 120
Query: 121 ISKVRSSVAYAVSAIAHWDWPEAWPQLFNLLMEMLVSGDLNAVHGAMRVLTEFTREVTDT 180
ISKVRSSVAYAVSAIAHWDWPEAWPQLFNLLMEMLVSGDLNAVHGAMRVLTEFTREVTDT
Sbjct: 121 ISKVRSSVAYAVSAIAHWDWPEAWPQLFNLLMEMLVSGDLNAVHGAMRVLTEFTREVTDT 180
Query: 181 QMPLVAPVILPEMYKIFTMAEVYGIRTRSRAVEIFTTCAHMICNMEELEKGAAKVLIFPV 240
QMPLVAPVILPEMYKIFTMAEVYGIRTRSRAVEIFTTCAHMICNMEELEKGAAKVLIFPV
Sbjct: 181 QMPLVAPVILPEMYKIFTMAEVYGIRTRSRAVEIFTTCAHMICNMEELEKGAAKVLIFPV 240
Query: 241 VQQFTEAFVQALQIPDGPTSDSGFKMEVLKAVTALVKNFPKHMVSSMQQILPIVWNTLTE 300
VQQFTEAFVQALQIPDGPTSDSGFKMEVLKAVTALVKNFPKHMVSSMQQILPIVWNTLTE
Sbjct: 241 VQQFTEAFVQALQIPDGPTSDSGFKMEVLKAVTALVKNFPKHMVSSMQQILPIVWNTLTE 300
Query: 301 SAAFYVRTEVNYTEEVEDPVDSDGEVLGFENLVFSIFEFVHALLENSKFKSTVKKALPEL 360
SAAFYVRTEVNYTEEVEDPVDSDGEVLGFENLVFSIFEFVHALLENSKFKSTVKKALPEL
Sbjct: 301 SAAFYVRTEVNYTEEVEDPVDSDGEVLGFENLVFSIFEFVHALLENSKFKSTVKKALPEL 360
Query: 361 IYYIILYMQITEEQIKVWTANPQQFVEDEDDDTFSYTVRIAAQDLLLAVATDFQNESAAA 420
IYYIILYMQITEEQIKVWTANPQQFVEDEDDDTFSYTVRIAAQDLLLAVATDFQNESAAA
Sbjct: 361 IYYIILYMQITEEQIKVWTANPQQFVEDEDDDTFSYTVRIAAQDLLLAVATDFQNESAAA 420
Query: 421 LAAAATRHLQEAEQTKNSGTEHWWKIHEACMLALGSVKAIITDSVKNGRIHFDMHGFLTN 480
LAAAATRHLQEAEQTKNSGTEHWWKIHEACMLALGSVKAIITDSVKNGRIHFDMHGFLTN
Sbjct: 421 LAAAATRHLQEAEQTKNSGTEHWWKIHEACMLALGSVKAIITDSVKNGRIHFDMHGFLTN 480
Query: 481 VILADLNLSVSPFLLGRALWAASRFTVAMSPELIQQFLQATVSGLHETQPPSVRISAVRA 540
VILADLNLSVSPFLLGRALWAASRFTVAMSPELIQQFLQATVSGLHETQPPSVRISAVRA
Sbjct: 481 VILADLNLSVSPFLLGRALWAASRFTVAMSPELIQQFLQATVSGLHETQPPSVRISAVRA 540
Query: 541 IWGYCDQLKVSESTHVLQPFLPSILDGLIHLAAQFSSEVLNLVMETLCIVCTVDPEFTAS 600
IWGYCDQLKVSESTHVLQPFLPSILDGLIHLAAQFSSEVLNLVMETLCIVCTVDPEFTAS
Sbjct: 541 IWGYCDQLKVSESTHVLQPFLPSILDGLIHLAAQFSSEVLNLVMETLCIVCTVDPEFTAS 600
Query: 601 MESKICPFTIAIFLKYSNDPVVASLAQDIFKELSQIEACQGPMQMRLIPTLVSIMQAPAD 660
MESKICPFTIAIFLKYSNDPVVASLAQDIFKELSQIEACQGPMQMRLIPTLVSIMQAPAD
Sbjct: 601 MESKICPFTIAIFLKYSNDPVVASLAQDIFKELSQIEACQGPMQMRLIPTLVSIMQAPAD 660
Query: 661 KIPAGLCATAIDILTTVVRNTKPPLSQLLICQAFPAVAQCTLHTDDNATMQNGGECLRAY 720
KIPAGLCATAIDILTTVVRNTKPPLSQLLICQAFPAVAQCTLHTDDNATMQNGGECLRAY
Sbjct: 661 KIPAGLCATAIDILTTVVRNTKPPLSQLLICQAFPAVAQCTLHTDDNATMQNGGECLRAY 720
Query: 721 VSVTLEQVAQWHDEQGHNGLWYVMQVVSQLLDPRTSEFTAAFVGRLVSTLISKAGRELGE 780
VSVTLEQVAQWHDEQGHNGLWYVMQVVSQLLDPRTSEFTAAFVGRLVSTLISKAGRELGE
Sbjct: 721 VSVTLEQVAQWHDEQGHNGLWYVMQVVSQLLDPRTSEFTAAFVGRLVSTLISKAGRELGE 780
Query: 781 NLDQILRAILSKMQQAETLSVMQSLIMVFAHLVHTQLEPLLEFLCSLPGPTGKPALEFVM 840
NLDQILRAILSKMQQAETLSVMQSLIMVFAHLVHTQLEPLLEFLCSLPGPTGKPALEFVM
Sbjct: 781 NLDQILRAILSKMQQAETLSVMQSLIMVFAHLVHTQLEPLLEFLCSLPGPTGKPALEFVM 840
Query: 841 AEWTSRQHLFYGQYEGKVSSVALCKLLQHGINADDKRLQDIRVKGEEIYSMDEGIRTRSK 900
AEWTSRQHLFYGQYEGKVSSVALCKLLQHGINADDKRLQDIRVKGEEIYSMDEGIRTRSK
Sbjct: 841 AEWTSRQHLFYGQYEGKVSSVALCKLLQHGINADDKRLQDIRVKGEEIYSMDEGIRTRSK 900
Query: 901 SAKNPERWTNIPLLVKILKLIINELSNVMEANAARQATPAEWSQDDSNDMWEDQEEEEEE 960
SAKNPERWTNIPLLVKILKLIINELSNVMEANAARQATPAEWSQDDSNDMWEDQEEEEEE
Sbjct: 901 SAKNPERWTNIPLLVKILKLIINELSNVMEANAARQATPAEWSQDDSNDMWEDQEEEEEE 960
Query: 961 EEDGLAGQLLSDILATSKYEEDYYEDDEEDDPDALKDPLYQIDLQAYLTDFLCQFAQQPC 1020
EEDGLAGQLLSDILATSKYEEDYYEDDEEDDPDALKDPLYQIDLQAYLTDFLCQFAQQPC
Sbjct: 961 EEDGLAGQLLSDILATSKYEEDYYEDDEEDDPDALKDPLYQIDLQAYLTDFLCQFAQQPC 1020
Query: 1021 YIMFSGHLNDNERRVLQTIGI 1041
YIMFSGHLNDNERRVLQTIGI
Sbjct: 1021 YIMFSGHLNDNERRVLQTIGI 1041
>gi|198041777 Ran binding protein 11 isoform 1 [Homo sapiens]
Length = 1015
Score = 71.6 bits (174), Expect = 4e-12
Identities = 117/592 (19%), Positives = 217/592 (36%), Gaps = 73/592 (12%)
Query: 25 LVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHLAELTVDPQGALAIRQLASVILKQY 84
++ LT S V AEEQ+K E F L + + + +R LA + K
Sbjct: 50 VLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINVRWLAVLYFKHG 109
Query: 85 VETHWCAQSEKFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSAIAHWDWPEAW 144
++ +W + P +E K +R L E I+++ + +A ++ +A D P W
Sbjct: 110 IDRYW----RRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQW 165
Query: 145 PQLFNLLMEMLVSGDLNAVHGAMRVLTEFTREVTDTQMPLVAPVILPEMYKIFTMA-EVY 203
P+L L+E + D H A+ T+ + ++ + I+ A ++
Sbjct: 166 PELIPTLIESVKVQDDLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLW 225
Query: 204 GIRTRSRAVEIFTTCAHMICNMEELEKGAAKVLIFPVVQQFT----------------EA 247
T + E+ + I + E + KVL V F E
Sbjct: 226 NHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGFLHGIFER 285
Query: 248 FVQALQIPDGPTSDSGFKMEVLKAVTALVKNFPKHMVSSMQQILPIVWNTLTESAAFYVR 307
Q L+ +D+ + + K + K + P++ +L E + YV
Sbjct: 286 LKQFLECSRSIGTDNVCRDRLEKTIILFTKVLLDFLDQHPFSFTPLIQRSL-EFSVSYVF 344
Query: 308 TEVNYTEEVEDPVDSDGEVLGFENLVFSIFEFVHALLENSKFKST--------------- 352
TEV GE + FE + + +++N +K +
Sbjct: 345 TEV-------------GEGVTFERFIVQCMNLIKMIVKNYAYKPSKNFEDSSPETLEAHK 391
Query: 353 VKKA------LPELIYYIIL-YMQITEEQIKVWTANPQQF-VEDEDDDTFSYTVRIAAQD 404
+K A L E+ ++ Y +TEE++ +W +P+ F VE+ D++ Y++R +
Sbjct: 392 IKMAFFTYPTLTEICRRLVSHYFLLTEEELTMWEEDPEGFTVEETGGDSWKYSLRPCTEV 451
Query: 405 LLLAVATDFQNESAAALAAAATRHLQEAEQTKNSGTEHWWKIHEACMLALGSVKAIITDS 464
L + D +E L +Q + N + I +A A+G + DS
Sbjct: 452 LFI----DIFHEYNQTLTPVLLEMMQTLQGPTNVEDMNALLIKDAVYNAVGLAAYELFDS 507
Query: 465 VKNGRIHFDMHGFLTNVILADLNLSVSPF--LLGRALWAASRFTVAMSPELIQQFLQATV 522
V D + N +L +L + + + L R +W ++ ++ L +
Sbjct: 508 V-------DFDQWFKNQLLPELQVIHNRYKPLRRRVIWLIGQWISVKFKSDLRPMLYEAI 560
Query: 523 SGLHETQPPSVRISAVRAIWGYCDQLKVSESTHVLQPFLPSILDGLIHLAAQ 574
L + Q VRI + D + T P+L ++ L L Q
Sbjct: 561 CNLLQDQDLVVRIETATTLKLTVDDFEF--RTDQFLPYLETMFTLLFQLLQQ 610
Score = 33.9 bits (76), Expect = 0.82
Identities = 61/320 (19%), Positives = 124/320 (38%), Gaps = 27/320 (8%)
Query: 443 WWKIHEACMLALGSVKAIITDSVKNGRIHFDMHGFLTNVILADLNLSVSP--FLL--GRA 498
W + E ML + +I G +++ FL VI ++S P +LL G
Sbjct: 650 WKQSEEHNMLRCAILTTLIHLVQGLGADSKNLYPFLLPVIQLSTDVSQPPHVYLLEDGLE 709
Query: 499 LWAAS-RFTVAMSPELIQQFLQATVSGLHETQPPSVRISAVRAIWGYCDQLKVSESTHVL 557
LW + + ++PEL++ F +S L E ++R + + I GY ST L
Sbjct: 710 LWLVTLENSPCITPELLRIF--QNMSPLLELSSENLR-TCFKIINGYI----FLSSTEFL 762
Query: 558 QPFLPSILDGLIHLAAQFSSEVLNLVMETLCIVCTVDPEFTASMESKICPFTIAIFLKYS 617
Q + + L + ++E V++ + V+P M I P+ ++
Sbjct: 763 QTYAVGLCQSFCELLKEITTEGQVQVLKVVENALKVNPILGPQMFQPILPYVFKGIIEGE 822
Query: 618 NDPVVASLAQDIFKELSQIEACQGPMQMRLIPTLVSIMQAPADKIPAGLCATAIDILTTV 677
PVV S + + ++ L+ + D++ + +D + +
Sbjct: 823 RYPVVMSTYLGV---MGRVLLQNTSFFSSLLNEMAHKFNQEMDQLLGNMIEMWVDRMDNI 879
Query: 678 VRNTKPPLSQLLICQAFPAVAQCTLHTDDNATMQNGGECLRAYVSVTLEQVAQWHDEQGH 737
+ + LS L + P+ DN+ +Q + +++++E + E
Sbjct: 880 TQPERRKLSALALLSLLPS---------DNSVIQ---DKFCGIINISVEGLHDVMTEDPE 927
Query: 738 NGLWYVMQVVSQLLDPRTSE 757
G + ++S L +P+ +E
Sbjct: 928 TGTYKDCMLMSHLEEPKVTE 947
>gi|39725950 Ran binding protein 11 isoform 2 [Homo sapiens]
Length = 975
Score = 71.6 bits (174), Expect = 4e-12
Identities = 117/592 (19%), Positives = 217/592 (36%), Gaps = 73/592 (12%)
Query: 25 LVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHLAELTVDPQGALAIRQLASVILKQY 84
++ LT S V AEEQ+K E F L + + + +R LA + K
Sbjct: 10 VLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINVRWLAVLYFKHG 69
Query: 85 VETHWCAQSEKFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSAIAHWDWPEAW 144
++ +W + P +E K +R L E I+++ + +A ++ +A D P W
Sbjct: 70 IDRYW----RRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQW 125
Query: 145 PQLFNLLMEMLVSGDLNAVHGAMRVLTEFTREVTDTQMPLVAPVILPEMYKIFTMA-EVY 203
P+L L+E + D H A+ T+ + ++ + I+ A ++
Sbjct: 126 PELIPTLIESVKVQDDLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLW 185
Query: 204 GIRTRSRAVEIFTTCAHMICNMEELEKGAAKVLIFPVVQQFT----------------EA 247
T + E+ + I + E + KVL V F E
Sbjct: 186 NHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGFLHGIFER 245
Query: 248 FVQALQIPDGPTSDSGFKMEVLKAVTALVKNFPKHMVSSMQQILPIVWNTLTESAAFYVR 307
Q L+ +D+ + + K + K + P++ +L E + YV
Sbjct: 246 LKQFLECSRSIGTDNVCRDRLEKTIILFTKVLLDFLDQHPFSFTPLIQRSL-EFSVSYVF 304
Query: 308 TEVNYTEEVEDPVDSDGEVLGFENLVFSIFEFVHALLENSKFKST--------------- 352
TEV GE + FE + + +++N +K +
Sbjct: 305 TEV-------------GEGVTFERFIVQCMNLIKMIVKNYAYKPSKNFEDSSPETLEAHK 351
Query: 353 VKKA------LPELIYYIIL-YMQITEEQIKVWTANPQQF-VEDEDDDTFSYTVRIAAQD 404
+K A L E+ ++ Y +TEE++ +W +P+ F VE+ D++ Y++R +
Sbjct: 352 IKMAFFTYPTLTEICRRLVSHYFLLTEEELTMWEEDPEGFTVEETGGDSWKYSLRPCTEV 411
Query: 405 LLLAVATDFQNESAAALAAAATRHLQEAEQTKNSGTEHWWKIHEACMLALGSVKAIITDS 464
L + D +E L +Q + N + I +A A+G + DS
Sbjct: 412 LFI----DIFHEYNQTLTPVLLEMMQTLQGPTNVEDMNALLIKDAVYNAVGLAAYELFDS 467
Query: 465 VKNGRIHFDMHGFLTNVILADLNLSVSPF--LLGRALWAASRFTVAMSPELIQQFLQATV 522
V D + N +L +L + + + L R +W ++ ++ L +
Sbjct: 468 V-------DFDQWFKNQLLPELQVIHNRYKPLRRRVIWLIGQWISVKFKSDLRPMLYEAI 520
Query: 523 SGLHETQPPSVRISAVRAIWGYCDQLKVSESTHVLQPFLPSILDGLIHLAAQ 574
L + Q VRI + D + T P+L ++ L L Q
Sbjct: 521 CNLLQDQDLVVRIETATTLKLTVDDFEF--RTDQFLPYLETMFTLLFQLLQQ 570
Score = 33.9 bits (76), Expect = 0.82
Identities = 61/320 (19%), Positives = 124/320 (38%), Gaps = 27/320 (8%)
Query: 443 WWKIHEACMLALGSVKAIITDSVKNGRIHFDMHGFLTNVILADLNLSVSP--FLL--GRA 498
W + E ML + +I G +++ FL VI ++S P +LL G
Sbjct: 610 WKQSEEHNMLRCAILTTLIHLVQGLGADSKNLYPFLLPVIQLSTDVSQPPHVYLLEDGLE 669
Query: 499 LWAAS-RFTVAMSPELIQQFLQATVSGLHETQPPSVRISAVRAIWGYCDQLKVSESTHVL 557
LW + + ++PEL++ F +S L E ++R + + I GY ST L
Sbjct: 670 LWLVTLENSPCITPELLRIF--QNMSPLLELSSENLR-TCFKIINGYI----FLSSTEFL 722
Query: 558 QPFLPSILDGLIHLAAQFSSEVLNLVMETLCIVCTVDPEFTASMESKICPFTIAIFLKYS 617
Q + + L + ++E V++ + V+P M I P+ ++
Sbjct: 723 QTYAVGLCQSFCELLKEITTEGQVQVLKVVENALKVNPILGPQMFQPILPYVFKGIIEGE 782
Query: 618 NDPVVASLAQDIFKELSQIEACQGPMQMRLIPTLVSIMQAPADKIPAGLCATAIDILTTV 677
PVV S + + ++ L+ + D++ + +D + +
Sbjct: 783 RYPVVMSTYLGV---MGRVLLQNTSFFSSLLNEMAHKFNQEMDQLLGNMIEMWVDRMDNI 839
Query: 678 VRNTKPPLSQLLICQAFPAVAQCTLHTDDNATMQNGGECLRAYVSVTLEQVAQWHDEQGH 737
+ + LS L + P+ DN+ +Q + +++++E + E
Sbjct: 840 TQPERRKLSALALLSLLPS---------DNSVIQ---DKFCGIINISVEGLHDVMTEDPE 887
Query: 738 NGLWYVMQVVSQLLDPRTSE 757
G + ++S L +P+ +E
Sbjct: 888 TGTYKDCMLMSHLEEPKVTE 907
>gi|29029559 CSE1 chromosome segregation 1-like protein [Homo
sapiens]
Length = 971
Score = 59.7 bits (143), Expect = 1e-08
Identities = 93/493 (18%), Positives = 200/493 (40%), Gaps = 61/493 (12%)
Query: 23 EALVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHLAELTVDPQGALAIRQLASVILK 82
+ L + L L P +R AE+ ++ +E + + + L L Q + I+ ASV K
Sbjct: 9 QTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLLLTLLEKSQDNV-IKVCASVTFK 67
Query: 83 QYVETHWCAQSEKFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSAIAHWDWPE 142
Y++ +W ++ P + E ++ I+ + + + S +++ ++ A+S I D+P+
Sbjct: 68 NYIKRNWRIVEDE--PNKICEADRVAIKANIVHLMLSSPEQIQKQLSDAISIIGREDFPQ 125
Query: 143 AWPQLFNLLMEMLVSGDLNAVHGAMRVL--------TEFTREVTDTQMPLVAPVILPEMY 194
WP L ++ SGD + ++G +R EF T++ LV +
Sbjct: 126 KWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALPLT 185
Query: 195 KIFTMAEVYGIRTRSRAVEIFTTCAHMICNMEELEKGAAKVLIFPVVQQFTEAFVQALQI 254
+F +E+ +T A+ + A ++L ++ +L
Sbjct: 186 NLF-----------KATIELCSTHAN--------DASALRILFSSLI--LISKLFYSLNF 224
Query: 255 PDGPTSDSGFKMEVLKAVTALVKNFPKHMVSSMQQ---ILPIVWNTLTESAAFYVRTEVN 311
D P + L+ K + + ++ +L ++ + + ++AA Y +
Sbjct: 225 QDLPEFFEDNMETWMNNFHTLLTLDNKLLQTDDEEEAGLLELLKSQICDNAALYAQ---K 281
Query: 312 YTEEVE-----------DPVDSDGEVLGFENLVFSIFEFVHALLENSKFKSTV--KKALP 358
Y EE + + + + G+ + ++ LV + +F+ ++ E +K+ + L
Sbjct: 282 YDEEFQRYLPRFVTAIWNLLVTTGQEVKYDLLVSNAIQFLASVCERPHYKNLFEDQNTLT 341
Query: 359 ELIYYIIL-YMQITEEQIKVWTANPQQFVEDEDDDTFSYTVRIAAQDLLLAVATDFQNES 417
+ +I+ M+ + + N ++++ + + + T R AA DL+ + F+
Sbjct: 342 SICEKVIVPNMEFRAADEEAFEDNSEEYIRRDLEGSDIDTRRRAACDLVRGLCKFFEGPV 401
Query: 418 AAALAAAATRHLQEAEQTKNSGTEHWWKIHEACMLALGSVKAIITDSVKNGRIH----FD 473
+ LQ E KN WK +A + + S+ A + K+G +
Sbjct: 402 TGIFSGYVNSMLQ--EYAKNPSVN--WKHKDAAIYLVTSL-ASKAQTQKHGITQANELVN 456
Query: 474 MHGFLTNVILADL 486
+ F N IL DL
Sbjct: 457 LTEFFVNHILPDL 469
>gi|5453998 importin 7 [Homo sapiens]
Length = 1038
Score = 58.5 bits (140), Expect = 3e-08
Identities = 203/1094 (18%), Positives = 395/1094 (36%), Gaps = 183/1094 (16%)
Query: 25 LVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHLAELTVDPQGALAIRQLASVILKQY 84
+++ L G + P +R AAE Q+ + F L ++T+ Q L +RQ + LK
Sbjct: 6 IIEALRGTMDPA--LREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKNM 63
Query: 85 VETHWCAQSE---KFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSAIAHWDWP 141
+ +W + P E + IRE + + S +R + + I D+P
Sbjct: 64 ITQYWPDRETAPGDISPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDYP 123
Query: 142 EAWPQLFNLLMEMLVSGDLNAVHGAMRVLTEFTR----EVTDTQMPLVA------PVILP 191
W + + + L S + G + L + + + + + PLVA PV+
Sbjct: 124 SRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNYEYKKPEERSPLVAAMQHFLPVLKD 183
Query: 192 EMYKIFTMAEVYGIRTRSRAVEIFTTCAHMICNMEELEKGA----AKVLIFPVVQQFTEA 247
++ + + + + +IF +E + + ++L V +
Sbjct: 184 RFIQLLSDQSDQSVLIQKQIFKIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPNE 243
Query: 248 FVQ-----------------ALQIPDGPTSDSGFKMEVLKAVTALVKNFPKHMVSSMQQI 290
+Q AL I G V K + F K +QQ+
Sbjct: 244 TLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEVFLKAFAVGVQQV 303
Query: 291 LPIVWNTLTES---AAFYVRTEVNYTEEVEDPVDSDGEVLGFENLVFSIFEFVHALLENS 347
L V E A ++ +NY + L ++NL
Sbjct: 304 LLKVLYQYKEKQYMAPRVLQQTLNYINQ------GVSHALTWKNL--------------- 342
Query: 348 KFKSTVKKALPELIYYIILYMQITEEQIKVWTANPQQFVEDEDDDTFSYTVRIAAQDLLL 407
K ++ + ++I+ ++ Y EE +W +P +++ + D + A LL
Sbjct: 343 --KPHIQGIIQDVIFPLMCYTDADEE---LWQEDPYEYIRMKFDVFEDFISPTTAAQTLL 397
Query: 408 AVATDFQNESAAALAAAATRHLQE--AEQTKNSGTEHWWKIHEACMLALGSVKAIITDSV 465
A + E + L E A+ K G H +GS+ I+
Sbjct: 398 FTACSKRKEVLQKTMGFCYQILTEPNADPRKKDGALH----------MIGSLAEILLKK- 446
Query: 466 KNGRIHFDMHGFLTNVILADLNLSVSPFLLGRALWAASRFTVA--MSPELIQQFLQATVS 523
+I+ D ++ + L S ++ RA W F S + +Q L+ T
Sbjct: 447 ---KIYKDQMEYMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKSDQNLQTALELTRR 503
Query: 524 GLHETQPPSVRISAVRAIWGYCDQLKVS---ESTHVLQPFLPSILDGLIHLAAQFSSEVL 580
L + + V++ A A+ Q+ +S ++ + PF+ ++ L+H+ + ++ L
Sbjct: 504 CLIDDREMPVKVEAAIAL-----QVLISNQEKAKEYITPFIRPVMQALLHIIRETENDDL 558
Query: 581 -NLVMETLCIVCTVDPEFTASMESKICPFTIAIFLKYSNDPVVASLAQDIFKELSQIEAC 639
N++ + +C E++ + T + + ++ V D +E S +A
Sbjct: 559 TNVIQKMIC-------EYSEEVTPIAVEMTQHLAMTFNQ---VIQTGPD--EEGSDDKAV 606
Query: 640 QGPMQMRLIPTLVSIMQAPADKIPAGLCATAIDILTTVVRNTKP-------PLSQLLICQ 692
+ I TL+S+++ +I L + ++ TV++ L+ L CQ
Sbjct: 607 TAMGILNTIDTLLSVVE-DHKEITQQLEGICLQVIGTVLQQHVLEFYEEIFSLAHSLTCQ 665
Query: 693 AFPAVAQCTLHTDDNATMQNGGE-------CLRAYVSVTLEQVAQWHDEQGHNGLWYVMQ 745
L Q+G + L YV+V + + L +
Sbjct: 666 QVSPQMWQLLPLVFEVFQQDGFDYFTDMMPLLHNYVTVDTDTLL-----SDTKYLEMIYS 720
Query: 746 VVSQLLDPRTSEFTAAFVGRLVSTLISKA-GRELGENLDQILRAILSKM-QQAETLSVMQ 803
+ ++L E +L+ +I + GR + + + + A L ++ ++ +T +
Sbjct: 721 MCKKVLTGVAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVEAALERLTREVKTSELRT 780
Query: 804 SLIMVFAHLVHTQLEPLLEFLCSLPGPTG-KPALEFVMAEWTSRQHLFYGQYEGKVSSVA 862
+ V ++ LL L +L P +P + +W + F G ++ K+ +
Sbjct: 781 MCLQVAIAALYYNPHLLLNTLENLRFPNNVEPVTNHFITQWLNDVDCFLGLHDRKMCVLG 840
Query: 863 LCKLLQHGINADDKRLQDI--RVKGEEIYSMDEGIRTRSKSAKNPERWTNIPLLVKILKL 920
LC L+ D +++ + +V G+ ++ L
Sbjct: 841 LCALI------DMEQIPQVLNQVSGQ---------------------------ILPAFIL 867
Query: 921 IINELSNVMEANAARQATPAEWSQDDSNDMWEDQEEEEE--EEEDGL--AGQLLSDILAT 976
+ N L +A + + D +D ED +E EE +ED + GQ +ILA
Sbjct: 868 LFNGLKRAYACHAEHE------NDSDDDDEAEDDDETEELGSDEDDIDEDGQEYLEILAK 921
Query: 977 SKYEEDYYEDDEEDDPD--ALKDPLYQID--------LQAYLTDFLCQFAQQPCYIMFSG 1026
E+ ED EEDD + AL+ ID Q + F + P +
Sbjct: 922 QAGEDGDDEDWEEDDAEETALEGYSTIIDDEDNPVDEYQIFKAIFQTIQNRNPVWYQALT 981
Query: 1027 H-LNDNERRVLQTI 1039
H LN+ +R+ LQ I
Sbjct: 982 HGLNEEQRKQLQDI 995
>gi|53759103 importin 8 [Homo sapiens]
Length = 1037
Score = 57.8 bits (138), Expect = 5e-08
Identities = 192/1086 (17%), Positives = 403/1086 (37%), Gaps = 168/1086 (15%)
Query: 25 LVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHLAELTVDPQGALAIRQLASVILKQY 84
++ L G + P ++R AAE ++ F L + V +RQ A++ LK
Sbjct: 6 IIQALKGTIDP--KLRIAAENELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYLKNM 63
Query: 85 VETHWCAQ----SEKFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSAIAHWDW 140
V +W + E P E + IR+ + G+ S VR + + AI D+
Sbjct: 64 VTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMCLRAIIKHDF 123
Query: 141 PEAWPQLFNLLMEMLVSGDLNAVHGAMRVLTEFT----------REVTDTQMPLVAPVIL 190
P WP + + + L S + G++ L + RE M + P I
Sbjct: 124 PGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTYEYKKAEEREPLIIAMQIFLPRIQ 183
Query: 191 PEMYKIFTMAEVYGIRTRSRAVEIFTTCAHMICNMEELEKGAAKVLIFPVVQQFTEAFVQ 250
++ ++ + Y + + + ++IF ++ + + + +
Sbjct: 184 QQIVQLLPDSSYYSVLLQKQILKIFYALVQYALPLQLVNNQTMTTWM-----EIFRTIID 238
Query: 251 ALQIPDGPTSDSGFKMEVLKAVTALVKNFPKHMVSSMQQILPIVWNTLT---ESAAFYVR 307
P+ D + E+ V K + H+V+ + + N E + F+++
Sbjct: 239 RTVPPETLHIDEDDRPEL---VWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLK 295
Query: 308 TEVNYTEEVEDPVDSDGEVLGF--ENLVFSIFEFVHALLENS----KFKSTVKKALPELI 361
T ++V + + ++ F +++ + +S + K ++ ++I
Sbjct: 296 TYAVGIQQVLLKILDQYRQKEYVAPRVLQQAFNYLNQGVVHSITWKQMKPHIQNISEDVI 355
Query: 362 YYIILYMQITEEQIKVWTANPQQFVEDEDDDTFSYTVRIAAQDLLLAVATDFQNESAAAL 421
+ ++ Y EE +W +P +++ + D Y A LL A + E +
Sbjct: 356 FSVMCYKDEDEE---LWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKM 412
Query: 422 AAAATRHLQEA--EQTKNSGTEHWWKIHEACMLALGSVKAIITDSVKNGRIHFDMHGFLT 479
A + L + + K G H +GS+ I+ +K M FL
Sbjct: 413 MAFCYQILTDPNFDPRKKDGALH----------VIGSLAEIL---LKKSLFKDQMELFLQ 459
Query: 480 NVILADLNLSVSPFLLGRALWAASRF-TVAMSPEL-IQQFLQATVSGLHETQPPSVRISA 537
N + L LS +L R+ W F ++ EL ++ ++ L E + V++ A
Sbjct: 460 NHVF-PLLLSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIEDKEMPVKVEA 518
Query: 538 VRAIWG-YCDQLKVSESTHVLQPFLPSILDGLIHLAAQFSSEVLNLVMETLCIVCTVDPE 596
A+ +Q++ E ++P + I+ L+H+ + ++ + V++ + +C E
Sbjct: 519 ALALQSLISNQIQAKE---YMKPHVRPIMQELLHIVRETENDDVTNVIQKM--ICEYSQE 573
Query: 597 FTASMESKICPFTIAIFLKYSNDPVVASLAQDIFKELSQIEACQGPMQMRLIPTLVSIMQ 656
AS+ + IF K L D ++E+ + M M ++ T+ +I+
Sbjct: 574 -VASIAVDMTQHLAEIFGKV--------LQSDEYEEVED----KTVMAMGILHTIDTILT 620
Query: 657 APAD-----KIPAGLCATAIDIL-----------------TTVVRNTKPPLSQLLICQAF 694
D + +C ID++ + + P + QLL
Sbjct: 621 VVEDHKEITQQLENICLRIIDLVLQKHVIEFYEEILSLAYSLTCHSISPQMWQLLGILYE 680
Query: 695 PAVAQCTLHTDDNATMQNGGECLRAYVSVTLEQVAQWHDEQGHNGLWYVMQVVSQLLDPR 754
C + D + L YV++ + + L + + ++L
Sbjct: 681 VFQQDCFEYFTDMMPL------LHNYVTIDTDTLL-----SNAKHLEILFTMCRKVLCGD 729
Query: 755 TSEFTAAFVGRLVSTLISKA-GRELGENLDQILRAILSKMQQAETLSVMQSL-IMVFAHL 812
E +L+ +I + GR + + + ++ +L ++ + S ++++ + V
Sbjct: 730 AGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVQLVLERLTRGVKTSELRTMCLQVAIAA 789
Query: 813 VHTQLEPLLEFL--CSLPGPTGKPALEFVMAEWTSRQHLFYGQYEGKVSSVALCKLLQHG 870
++ + LL L LP G ++F+ +W + F G ++ K+ + L LL+
Sbjct: 790 LYYNPDLLLHTLERIQLPHNPGPITVQFI-NQWMNDTDCFLGHHDRKMCIIGLSILLE-- 846
Query: 871 INADDKRLQDIRVKGEEIYSMDEGIRTRSKSAKNPERWTNIPLLVKILKLIINELSNVME 930
++ R + ++ +I+ I+ + +
Sbjct: 847 ------------------------LQNRPPAVD--------AVVGQIVPSILFLFLGLKQ 874
Query: 931 ANAARQATPAE-WSQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEE 989
A RQ E S+ + DM E++E +EEE + Q + + + ED E+D++
Sbjct: 875 VCATRQLVNREDRSKAEKADMEENEEISSDEEETNVTAQAMQ---SNNGRGEDEEEEDDD 931
Query: 990 DDPDALKD--------PL--------YQIDLQAYLTDFLCQFAQQPCYIMFSGHLNDNER 1033
D + L++ PL YQ QA +T Q Y + L++++R
Sbjct: 932 WDEEVLEETALEGFSTPLDLDNSVDEYQFFTQALIT---VQSRDAAWYQLLMAPLSEDQR 988
Query: 1034 RVLQTI 1039
LQ +
Sbjct: 989 TALQEV 994
>gi|209969838 transportin 2 (importin 3, karyopherin beta 2b)
isoform 1 [Homo sapiens]
Length = 897
Score = 47.4 bits (111), Expect = 7e-05
Identities = 43/165 (26%), Positives = 75/165 (45%), Gaps = 11/165 (6%)
Query: 16 PVAQGLKEALVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHLA-ELTVDPQGALAIR 74
P QGL++ L L SP + ++++K L +F +L LT R
Sbjct: 5 PDEQGLQQVL-QLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDEPTR 63
Query: 75 QLASVILKQYVETHWCAQSEKFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSA 134
L+ +ILK V+ H+ + F PP A + +E L N + ++ S +R+++ ++
Sbjct: 64 SLSGLILKNNVKAHY----QSFPPPV----ADFIKQECL-NNIGDASSLIRATIGILITT 114
Query: 135 IAHWDWPEAWPQLFNLLMEMLVSGDLNAVHGAMRVLTEFTREVTD 179
IA + WP+L L +L S D N GA L + + ++
Sbjct: 115 IASKGELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSE 159
>gi|209969836 transportin 2 (importin 3, karyopherin beta 2b)
isoform 3 [Homo sapiens]
Length = 887
Score = 47.4 bits (111), Expect = 7e-05
Identities = 43/165 (26%), Positives = 75/165 (45%), Gaps = 11/165 (6%)
Query: 16 PVAQGLKEALVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHLA-ELTVDPQGALAIR 74
P QGL++ L L SP + ++++K L +F +L LT R
Sbjct: 5 PDEQGLQQVL-QLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDEPTR 63
Query: 75 QLASVILKQYVETHWCAQSEKFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSA 134
L+ +ILK V+ H+ + F PP A + +E L N + ++ S +R+++ ++
Sbjct: 64 SLSGLILKNNVKAHY----QSFPPPV----ADFIKQECL-NNIGDASSLIRATIGILITT 114
Query: 135 IAHWDWPEAWPQLFNLLMEMLVSGDLNAVHGAMRVLTEFTREVTD 179
IA + WP+L L +L S D N GA L + + ++
Sbjct: 115 IASKGELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSE 159
>gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isoform
2 [Homo sapiens]
Length = 887
Score = 47.4 bits (111), Expect = 7e-05
Identities = 43/165 (26%), Positives = 75/165 (45%), Gaps = 11/165 (6%)
Query: 16 PVAQGLKEALVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHLA-ELTVDPQGALAIR 74
P QGL++ L L SP + ++++K L +F +L LT R
Sbjct: 5 PDEQGLQQVL-QLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDEPTR 63
Query: 75 QLASVILKQYVETHWCAQSEKFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSA 134
L+ +ILK V+ H+ + F PP A + +E L N + ++ S +R+++ ++
Sbjct: 64 SLSGLILKNNVKAHY----QSFPPPV----ADFIKQECL-NNIGDASSLIRATIGILITT 114
Query: 135 IAHWDWPEAWPQLFNLLMEMLVSGDLNAVHGAMRVLTEFTREVTD 179
IA + WP+L L +L S D N GA L + + ++
Sbjct: 115 IASKGELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSE 159
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 45.1 bits (105), Expect = 4e-04
Identities = 64/269 (23%), Positives = 109/269 (40%), Gaps = 44/269 (16%)
Query: 745 QVVSQLLDPRTSEFTAAFVGRLVSTLISKAGRELGENLDQILRAILSKMQQAETLSVMQS 804
+V+ Q + R + + V R + LI+K G + + +LRA+ K +L + +
Sbjct: 251 RVIEQRIPYRGTRYPE--VNRRIERLINKPGPDTFPDYGDVLRAV-EKAAARHSLGLPRQ 307
Query: 805 LIMVFAHLV----------HTQLEPLLEFLCSLPG---PTGKPALEFVMAEWTSRQH--L 849
+ + A L+ + F C L P PAL + R++ L
Sbjct: 308 QLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPVLARRLRENRSL 367
Query: 850 FYGQYEGKVSSVALCKLLQHGINADDKRLQDIRVKGEEIYSMDEGIRTRSKSAKNPERWT 909
+ + +S A+ LQ +++ + R++G T S SA PE
Sbjct: 368 AMSRLDEVISKYAM---LQDKSEEGERKKRRARLQG-----------TSSHSADTPEA-- 411
Query: 910 NIPLLVKILKLIINELSNVMEANAARQATPAEWS-QDDSNDMWEDQEEEEEEEEDGLAGQ 968
L E + M + A+ AE +DD E++EEEEEEEE+ +
Sbjct: 412 ---------SLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSE 462
Query: 969 LLSDILATSKYEEDYYEDDEEDDPDALKD 997
D+ + +ED E+DEE++ A KD
Sbjct: 463 EEEDLEQMQEGQEDDEEEDEEEEAAAGKD 491
>gi|215422388 death-domain associated protein isoform a [Homo
sapiens]
Length = 740
Score = 45.1 bits (105), Expect = 4e-04
Identities = 64/269 (23%), Positives = 109/269 (40%), Gaps = 44/269 (16%)
Query: 745 QVVSQLLDPRTSEFTAAFVGRLVSTLISKAGRELGENLDQILRAILSKMQQAETLSVMQS 804
+V+ Q + R + + V R + LI+K G + + +LRA+ K +L + +
Sbjct: 251 RVIEQRIPYRGTRYPE--VNRRIERLINKPGPDTFPDYGDVLRAV-EKAAARHSLGLPRQ 307
Query: 805 LIMVFAHLV----------HTQLEPLLEFLCSLPG---PTGKPALEFVMAEWTSRQH--L 849
+ + A L+ + F C L P PAL + R++ L
Sbjct: 308 QLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPVLARRLRENRSL 367
Query: 850 FYGQYEGKVSSVALCKLLQHGINADDKRLQDIRVKGEEIYSMDEGIRTRSKSAKNPERWT 909
+ + +S A+ LQ +++ + R++G T S SA PE
Sbjct: 368 AMSRLDEVISKYAM---LQDKSEEGERKKRRARLQG-----------TSSHSADTPEA-- 411
Query: 910 NIPLLVKILKLIINELSNVMEANAARQATPAEWS-QDDSNDMWEDQEEEEEEEEDGLAGQ 968
L E + M + A+ AE +DD E++EEEEEEEE+ +
Sbjct: 412 ---------SLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSE 462
Query: 969 LLSDILATSKYEEDYYEDDEEDDPDALKD 997
D+ + +ED E+DEE++ A KD
Sbjct: 463 EEEDLEQMQEGQEDDEEEDEEEEAAAGKD 491
>gi|215422366 death-domain associated protein isoform b [Homo
sapiens]
Length = 752
Score = 45.1 bits (105), Expect = 4e-04
Identities = 64/269 (23%), Positives = 109/269 (40%), Gaps = 44/269 (16%)
Query: 745 QVVSQLLDPRTSEFTAAFVGRLVSTLISKAGRELGENLDQILRAILSKMQQAETLSVMQS 804
+V+ Q + R + + V R + LI+K G + + +LRA+ K +L + +
Sbjct: 263 RVIEQRIPYRGTRYPE--VNRRIERLINKPGPDTFPDYGDVLRAV-EKAAARHSLGLPRQ 319
Query: 805 LIMVFAHLV----------HTQLEPLLEFLCSLPG---PTGKPALEFVMAEWTSRQH--L 849
+ + A L+ + F C L P PAL + R++ L
Sbjct: 320 QLQLMAQDAFRDVGIRLQERRHLDLIYNFGCHLTDDYRPGVDPALSDPVLARRLRENRSL 379
Query: 850 FYGQYEGKVSSVALCKLLQHGINADDKRLQDIRVKGEEIYSMDEGIRTRSKSAKNPERWT 909
+ + +S A+ LQ +++ + R++G T S SA PE
Sbjct: 380 AMSRLDEVISKYAM---LQDKSEEGERKKRRARLQG-----------TSSHSADTPEA-- 423
Query: 910 NIPLLVKILKLIINELSNVMEANAARQATPAEWS-QDDSNDMWEDQEEEEEEEEDGLAGQ 968
L E + M + A+ AE +DD E++EEEEEEEE+ +
Sbjct: 424 ---------SLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSE 474
Query: 969 LLSDILATSKYEEDYYEDDEEDDPDALKD 997
D+ + +ED E+DEE++ A KD
Sbjct: 475 EEEDLEQMQEGQEDDEEEDEEEEAAAGKD 503
>gi|156071452 nardilysin isoform b [Homo sapiens]
Length = 1151
Score = 43.9 bits (102), Expect = 8e-04
Identities = 30/107 (28%), Positives = 57/107 (53%), Gaps = 11/107 (10%)
Query: 900 KSAKNPERWTNIPLLVKILKLIINELSNVMEANAARQATPAEWSQDDSNDMWEDQEEEEE 959
KS +P+++ I L + L+I++LSN ME + ++D E++ EEEE
Sbjct: 105 KSPSDPKQYRYIKLQNGLQALLISDLSN-MEGKTG----------NTTDDEEEEEVEEEE 153
Query: 960 EEEDGLAGQLLSDILATSKYEEDYYEDDEEDDPDALKDPLYQIDLQA 1006
E++D +G + D +ED ++D+ +DD D + L +++ +A
Sbjct: 154 EDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERA 200
>gi|156071450 nardilysin isoform a [Homo sapiens]
Length = 1219
Score = 43.9 bits (102), Expect = 8e-04
Identities = 30/107 (28%), Positives = 57/107 (53%), Gaps = 11/107 (10%)
Query: 900 KSAKNPERWTNIPLLVKILKLIINELSNVMEANAARQATPAEWSQDDSNDMWEDQEEEEE 959
KS +P+++ I L + L+I++LSN ME + ++D E++ EEEE
Sbjct: 105 KSPSDPKQYRYIKLQNGLQALLISDLSN-MEGKTG----------NTTDDEEEEEVEEEE 153
Query: 960 EEEDGLAGQLLSDILATSKYEEDYYEDDEEDDPDALKDPLYQIDLQA 1006
E++D +G + D +ED ++D+ +DD D + L +++ +A
Sbjct: 154 EDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERA 200
>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
Length = 1711
Score = 41.2 bits (95), Expect = 0.005
Identities = 19/56 (33%), Positives = 30/56 (53%)
Query: 936 QATPAEWSQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDD 991
+A W + + MW+ EEEEEEEE+GL + + KY+ Y ++ED+
Sbjct: 1297 RAREMPWRTEAARQMWDTNEEEEEEEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDE 1352
>gi|23510381 transportin 1 isoform 2 [Homo sapiens]
Length = 890
Score = 40.8 bits (94), Expect = 0.007
Identities = 47/189 (24%), Positives = 86/189 (45%), Gaps = 19/189 (10%)
Query: 16 PVAQGLKEALVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHLA-ELTVDPQGALAIR 74
P QGL++ L L SP ++ +++++ L +F +L LT R
Sbjct: 7 PDEQGLQQIL-QLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSEDEPTR 65
Query: 75 QLASVILKQYVETHWCAQSEKFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSA 134
L+ +ILK V+ H+ + F P T+ I+ N + +S +R++V ++
Sbjct: 66 SLSGLILKNNVKAHF----QNF-PNGVTD----FIKSECLNNIGDSSPLIRATVGILITT 116
Query: 135 IAHWDWPEAWPQLFNLLMEMLVSGDLN---AVHGAMRVLTEFTREVTDTQM---PLVAPV 188
IA + WP L L +L S D N GA++ + E + E+ D+ + PL +
Sbjct: 117 IASKGELQNWPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPL--NI 174
Query: 189 ILPEMYKIF 197
++P+ + F
Sbjct: 175 MIPKFLQFF 183
>gi|133925811 transportin 1 isoform 1 [Homo sapiens]
Length = 898
Score = 40.8 bits (94), Expect = 0.007
Identities = 47/189 (24%), Positives = 86/189 (45%), Gaps = 19/189 (10%)
Query: 16 PVAQGLKEALVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHLA-ELTVDPQGALAIR 74
P QGL++ L L SP ++ +++++ L +F +L LT R
Sbjct: 15 PDEQGLQQIL-QLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSEDEPTR 73
Query: 75 QLASVILKQYVETHWCAQSEKFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSA 134
L+ +ILK V+ H+ + F P T+ I+ N + +S +R++V ++
Sbjct: 74 SLSGLILKNNVKAHF----QNF-PNGVTD----FIKSECLNNIGDSSPLIRATVGILITT 124
Query: 135 IAHWDWPEAWPQLFNLLMEMLVSGDLN---AVHGAMRVLTEFTREVTDTQM---PLVAPV 188
IA + WP L L +L S D N GA++ + E + E+ D+ + PL +
Sbjct: 125 IASKGELQNWPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPL--NI 182
Query: 189 ILPEMYKIF 197
++P+ + F
Sbjct: 183 MIPKFLQFF 191
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 40.0 bits (92), Expect = 0.011
Identities = 20/66 (30%), Positives = 36/66 (54%)
Query: 932 NAARQATPAEWSQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDD 991
NA ++ + E D D +D++E+E+E+E A + S+ E+D ++D+EDD
Sbjct: 139 NAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDD 198
Query: 992 PDALKD 997
D +D
Sbjct: 199 DDDEED 204
Score = 39.3 bits (90), Expect = 0.020
Identities = 24/78 (30%), Positives = 41/78 (52%), Gaps = 9/78 (11%)
Query: 929 MEANAARQATPAEWSQDDSNDMWEDQEEEEEEEEDGL---------AGQLLSDILATSKY 979
M+A AA A+ E +DD +D +D +EE++ EE+ + A +++
Sbjct: 175 MKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAE 234
Query: 980 EEDYYEDDEEDDPDALKD 997
+ED EDDE++D D +D
Sbjct: 235 DEDEEEDDEDEDDDDDED 252
Score = 32.0 bits (71), Expect = 3.1
Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 14/71 (19%)
Query: 937 ATPAEWSQDDSNDMWEDQEEE--------------EEEEEDGLAGQLLSDILATSKYEED 982
A PA+ +++ N ED +EE E+E+ED + + A E++
Sbjct: 128 AIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDE 187
Query: 983 YYEDDEEDDPD 993
EDDE+D+ D
Sbjct: 188 DDEDDEDDEDD 198
Score = 31.2 bits (69), Expect = 5.3
Identities = 16/48 (33%), Positives = 25/48 (52%)
Query: 916 KILKLIINELSNVMEANAARQATPAEWSQDDSNDMWEDQEEEEEEEED 963
K K++ + NV E + E DD +D +D E++EEEEE+
Sbjct: 220 KAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEE 267
Score = 30.4 bits (67), Expect = 9.1
Identities = 13/20 (65%), Positives = 16/20 (80%)
Query: 944 QDDSNDMWEDQEEEEEEEED 963
+DD +D ED EEEEEEEE+
Sbjct: 251 EDDEDDDDEDDEEEEEEEEE 270
>gi|14249412 tripartite motif-containing 52 [Homo sapiens]
Length = 297
Score = 40.0 bits (92), Expect = 0.011
Identities = 19/51 (37%), Positives = 31/51 (60%)
Query: 945 DDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDDPDAL 995
D+ + MW+++EEEEEE++D G L D+ EE+ E +ED+ + L
Sbjct: 115 DNVDYMWDEEEEEEEEDQDYYLGGLRPDLRIDVYREEEILEAYDEDEDEEL 165
Score = 38.5 bits (88), Expect = 0.033
Identities = 17/66 (25%), Positives = 35/66 (53%), Gaps = 6/66 (9%)
Query: 932 NAARQATPAEWSQDDSNDMWEDQEEEEEEEEDGLAGQL------LSDILATSKYEEDYYE 985
N R WS++D D E+++E EEEE++ G + + ++L +E+ ++
Sbjct: 38 NFCRGCVTQLWSKEDEEDQNEEEDEWEEEEDEEAVGAMDGWDGSIREVLYRGNADEELFQ 97
Query: 986 DDEEDD 991
D ++D+
Sbjct: 98 DQDDDE 103
>gi|239747212 PREDICTED: hypothetical protein XP_002346939 [Homo
sapiens]
Length = 1158
Score = 39.3 bits (90), Expect = 0.020
Identities = 19/55 (34%), Positives = 34/55 (61%), Gaps = 2/55 (3%)
Query: 940 AEWSQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDDPDA 994
A Q+D + ED ++ EE++ED LAG+ D ++ + + YED+E+++P A
Sbjct: 1012 ASEKQEDVEE--EDDDDLEEDDEDSLAGKSQDDTVSPAPEPQAAYEDEEDEEPAA 1064
>gi|41349472 PR domain containing 16 isoform 2 [Homo sapiens]
Length = 1256
Score = 39.3 bits (90), Expect = 0.020
Identities = 19/55 (34%), Positives = 34/55 (61%), Gaps = 2/55 (3%)
Query: 940 AEWSQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDDPDA 994
A Q+D + ED ++ EE++ED LAG+ D ++ + + YED+E+++P A
Sbjct: 1110 ASEKQEDVEE--EDDDDLEEDDEDSLAGKSQDDTVSPAPEPQAAYEDEEDEEPAA 1162
>gi|41349470 PR domain containing 16 isoform 1 [Homo sapiens]
Length = 1275
Score = 39.3 bits (90), Expect = 0.020
Identities = 19/55 (34%), Positives = 34/55 (61%), Gaps = 2/55 (3%)
Query: 940 AEWSQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDDPDA 994
A Q+D + ED ++ EE++ED LAG+ D ++ + + YED+E+++P A
Sbjct: 1110 ASEKQEDVEE--EDDDDLEEDDEDSLAGKSQDDTVSPAPEPQAAYEDEEDEEPAA 1162
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 39.3 bits (90), Expect = 0.020
Identities = 33/130 (25%), Positives = 57/130 (43%), Gaps = 32/130 (24%)
Query: 871 INADDKRLQDIRVKG--EEIYSMDEGIRTRSKSAKNPERWTNIPLLVKILKLIINELSNV 928
++++D D + G EE+ ++ R R++SAK E L N+ S
Sbjct: 1336 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAE-------------LEENQRSYK 1382
Query: 929 MEANAARQATPAEWSQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDE 988
+ R + S ++ ++ E++EE+EEEEE EE+ E++E
Sbjct: 1383 QKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEE-----------------EEEEEEEEE 1425
Query: 989 EDDPDALKDP 998
ED+ D K P
Sbjct: 1426 EDENDDSKSP 1435
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 39.3 bits (90), Expect = 0.020
Identities = 33/130 (25%), Positives = 57/130 (43%), Gaps = 32/130 (24%)
Query: 871 INADDKRLQDIRVKG--EEIYSMDEGIRTRSKSAKNPERWTNIPLLVKILKLIINELSNV 928
++++D D + G EE+ ++ R R++SAK E L N+ S
Sbjct: 1374 VSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAE-------------LEENQRSYK 1420
Query: 929 MEANAARQATPAEWSQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDE 988
+ R + S ++ ++ E++EE+EEEEE EE+ E++E
Sbjct: 1421 QKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEE-----------------EEEEEEEEE 1463
Query: 989 EDDPDALKDP 998
ED+ D K P
Sbjct: 1464 EDENDDSKSP 1473
>gi|151101404 prothymosin, alpha isoform 2 [Homo sapiens]
Length = 110
Score = 37.7 bits (86), Expect = 0.057
Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 5/87 (5%)
Query: 915 VKILKLIINELSNVMEANAARQATPAEWSQDDSNDMWEDQEEE-----EEEEEDGLAGQL 969
+K K ++ E N +A A A Q+ N++ E++EE EEEE DG
Sbjct: 17 LKEKKEVVEEAENGRDAPANGNANEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDG 76
Query: 970 LSDILATSKYEEDYYEDDEEDDPDALK 996
D A S + EDDE+DD D K
Sbjct: 77 DEDEEAESATGKRAAEDDEDDDVDTKK 103
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 37.4 bits (85), Expect = 0.074
Identities = 21/74 (28%), Positives = 37/74 (50%), Gaps = 16/74 (21%)
Query: 930 EANAARQATPAEWSQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEE 989
E + + E +D+ + E++EEEEEEEE+ EE+ E++EE
Sbjct: 259 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEE----------------EEEEEEEEEE 302
Query: 990 DDPDALKDPLYQID 1003
++ +A D ++Q D
Sbjct: 303 EEEEAAPDVIFQED 316
>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member E isoform 1 [Homo sapiens]
Length = 268
Score = 37.4 bits (85), Expect = 0.074
Identities = 20/48 (41%), Positives = 28/48 (58%), Gaps = 9/48 (18%)
Query: 944 QDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDD 991
++D +D E+ EEEEEEEE GL G+ K + D +D EE+D
Sbjct: 229 EEDDDDYVEEGEEEEEEEEGGLRGE---------KRKRDAEDDGEEED 267
Score = 32.0 bits (71), Expect = 3.1
Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 7/49 (14%)
Query: 945 DDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDDPD 993
D + ED +E++EEEE+ AG YEE+ E++EED+ +
Sbjct: 157 DSEEEDDEDGDEDDEEEEENEAG-------PPEGYEEEEEEEEEEDEDE 198
Score = 31.6 bits (70), Expect = 4.1
Identities = 17/75 (22%), Positives = 38/75 (50%), Gaps = 11/75 (14%)
Query: 930 EANAARQATPAE-WSQDDSNDMWEDQEEEEEEEEDGLA----------GQLLSDILATSK 978
E +A P E + +++ + ED++E+E+E+E G L+ + + +
Sbjct: 171 EEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEE 230
Query: 979 YEEDYYEDDEEDDPD 993
++DY E+ EE++ +
Sbjct: 231 DDDDYVEEGEEEEEE 245
>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 2 [Homo sapiens]
Length = 227
Score = 37.4 bits (85), Expect = 0.074
Identities = 20/48 (41%), Positives = 28/48 (58%), Gaps = 9/48 (18%)
Query: 944 QDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDD 991
++D +D E+ EEEEEEEE GL G+ K + D +D EE+D
Sbjct: 188 EEDDDDYVEEGEEEEEEEEGGLRGE---------KRKRDAEDDGEEED 226
Score = 32.0 bits (71), Expect = 3.1
Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 7/49 (14%)
Query: 945 DDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDDPD 993
D + ED +E++EEEE+ AG YEE+ E++EED+ +
Sbjct: 116 DSEEEDDEDGDEDDEEEEENEAG-------PPEGYEEEEEEEEEEDEDE 157
Score = 31.6 bits (70), Expect = 4.1
Identities = 17/75 (22%), Positives = 38/75 (50%), Gaps = 11/75 (14%)
Query: 930 EANAARQATPAE-WSQDDSNDMWEDQEEEEEEEEDGLA----------GQLLSDILATSK 978
E +A P E + +++ + ED++E+E+E+E G L+ + + +
Sbjct: 130 EEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEE 189
Query: 979 YEEDYYEDDEEDDPD 993
++DY E+ EE++ +
Sbjct: 190 DDDDYVEEGEEEEEE 204
>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 3 [Homo sapiens]
Length = 220
Score = 37.4 bits (85), Expect = 0.074
Identities = 20/48 (41%), Positives = 28/48 (58%), Gaps = 9/48 (18%)
Query: 944 QDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDD 991
++D +D E+ EEEEEEEE GL G+ K + D +D EE+D
Sbjct: 181 EEDDDDYVEEGEEEEEEEEGGLRGE---------KRKRDAEDDGEEED 219
Score = 32.0 bits (71), Expect = 3.1
Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 7/49 (14%)
Query: 945 DDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDDPD 993
D + ED +E++EEEE+ AG YEE+ E++EED+ +
Sbjct: 109 DSEEEDDEDGDEDDEEEEENEAG-------PPEGYEEEEEEEEEEDEDE 150
Score = 31.6 bits (70), Expect = 4.1
Identities = 17/75 (22%), Positives = 38/75 (50%), Gaps = 11/75 (14%)
Query: 930 EANAARQATPAE-WSQDDSNDMWEDQEEEEEEEEDGLA----------GQLLSDILATSK 978
E +A P E + +++ + ED++E+E+E+E G L+ + + +
Sbjct: 123 EEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEE 182
Query: 979 YEEDYYEDDEEDDPD 993
++DY E+ EE++ +
Sbjct: 183 DDDDYVEEGEEEEEE 197
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 37.0 bits (84), Expect = 0.097
Identities = 18/51 (35%), Positives = 31/51 (60%), Gaps = 5/51 (9%)
Query: 943 SQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDDPD 993
S D+ + E++EEEEEEEE+ D + EE+Y+E++EE++ +
Sbjct: 885 SSDEEEEEEEEEEEEEEEEEEE-----EEDFEEEEEDEEEYFEEEEEEEEE 930
Score = 32.0 bits (71), Expect = 3.1
Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 7/53 (13%)
Query: 941 EWSQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDDPD 993
E ++D + +E++EEEEEE E+ + + EE+ E+DEE++ +
Sbjct: 911 EEEEEDEEEYFEEEEEEEEEFEEEFEEE-------EGELEEEEEEEDEEEEEE 956
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.132 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,666,191
Number of Sequences: 37866
Number of extensions: 1577403
Number of successful extensions: 12479
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 83
Number of HSP's successfully gapped in prelim test: 106
Number of HSP's that attempted gapping in prelim test: 10037
Number of HSP's gapped (non-prelim): 1106
length of query: 1041
length of database: 18,247,518
effective HSP length: 112
effective length of query: 929
effective length of database: 14,006,526
effective search space: 13012062654
effective search space used: 13012062654
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.