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Search of human proteins with 21361356
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361356 translocase of outer mitochondrial membrane 34
[Homo sapiens]
(309 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361356 translocase of outer mitochondrial membrane 34 [Homo... 613 e-176
gi|27262638 sperm associated antigen 1 [Homo sapiens] 270 1e-72
gi|27262636 sperm associated antigen 1 [Homo sapiens] 270 1e-72
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 114 8e-26
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 113 2e-25
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H... 103 2e-22
gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens] 84 1e-16
gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens] 78 1e-14
gi|4503729 FK506 binding protein 52 [Homo sapiens] 76 3e-14
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens] 76 3e-14
gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens] 75 7e-14
gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens] 75 7e-14
gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens] 75 7e-14
gi|29725607 smooth muscle cell associated protein-1 isoform 2 [H... 73 4e-13
gi|54607135 translocase of outer mitochondrial membrane 70 homol... 72 5e-13
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-... 72 8e-13
gi|89179321 smooth muscle cell associated protein-1 isoform 3 [H... 70 2e-12
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi... 70 3e-12
gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens] 69 4e-12
gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens] 69 4e-12
gi|56181387 STIP1 homology and U-box containing protein 1 [Homo ... 68 9e-12
gi|17149853 WAF-1/CIP1 stabilizing protein 39 [Homo sapiens] 68 9e-12
gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 68 1e-11
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform... 68 1e-11
gi|4826932 peptidylprolyl isomerase D [Homo sapiens] 65 8e-11
gi|201860300 aryl hydrocarbon receptor interacting protein [Homo... 65 1e-10
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens] 60 2e-09
gi|27881484 zinc finger CCCH-type containing 7B [Homo sapiens] 59 5e-09
gi|156627581 tetratricopeptide repeat domain 4 [Homo sapiens] 58 9e-09
gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Hom... 57 2e-08
>gi|21361356 translocase of outer mitochondrial membrane 34 [Homo
sapiens]
Length = 309
Score = 613 bits (1582), Expect = e-176
Identities = 309/309 (100%), Positives = 309/309 (100%)
Query: 1 MAPKFPDSVEELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAAC 60
MAPKFPDSVEELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAAC
Sbjct: 1 MAPKFPDSVEELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAAC 60
Query: 61 HLKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTS 120
HLKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTS
Sbjct: 61 HLKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTS 120
Query: 121 AVEGINRMTRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTAT 180
AVEGINRMTRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTAT
Sbjct: 121 AVEGINRMTRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTAT 180
Query: 181 KNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVL 240
KNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVL
Sbjct: 181 KNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVL 240
Query: 241 KQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKL 300
KQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKL
Sbjct: 241 KQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKL 300
Query: 301 RQEVKQNLH 309
RQEVKQNLH
Sbjct: 301 RQEVKQNLH 309
>gi|27262638 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 270 bits (690), Expect = 1e-72
Identities = 145/299 (48%), Positives = 199/299 (66%), Gaps = 8/299 (2%)
Query: 12 LRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCI 71
L++ GNE FR+GQ+AEA+ Y A+ +L+ GS ++ S+LYSNRAAC+LK+GNC CI
Sbjct: 448 LKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDLSILYSNRAACYLKEGNCSGCI 507
Query: 72 KDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTRA 131
+DC AL L PFS+KPLLRRA AYE LE+Y AYVDYKTVLQID + A + +NR++R
Sbjct: 508 QDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQIDCGLQLANDSVNRLSRI 567
Query: 132 LMDSLGPEWRLKLPSIPLVPVSAQ-KRWNSLPSENHKEMAKSKSKETTATKNRVPSAGDV 190
LM+ GP WR KL IP VP S + W+ KEM ++ ++++ +R D
Sbjct: 568 LMELDGPNWREKLSPIPAVPASVPLQAWHPA-----KEMISKQAGDSSS--HRQQGITDE 620
Query: 191 EKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDC 250
+ + LKEEGN+ V N+K A+ KYSE L +N E A Y+NRALCYL L Q+ EA +DC
Sbjct: 621 KTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECAIYTNRALCYLKLCQFEEAKQDC 680
Query: 251 TEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQNLH 309
+AL+L NVKAFYRRA AHK LK+Y+ S D++ ++ ++P A+ +EV + L+
Sbjct: 681 DQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILLDPSIIEAKMELEEVTRLLN 739
Score = 78.2 bits (191), Expect = 9e-15
Identities = 47/150 (31%), Positives = 80/150 (53%), Gaps = 6/150 (4%)
Query: 164 ENHKEMAKSKSKETTATKNRVPSAGDVEKARVL-----KEEGNELVKKGNHKKAIEKYSE 218
E++KE + + R+ +AG EK + KE+GNE G++++A+ Y+
Sbjct: 175 EDYKEKTVIDKSHLSKIETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTR 234
Query: 219 SLLCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYK 278
S+ A Y+NRA + L+ + A +DC + L+L+ NVKA RRA +K +
Sbjct: 235 SISALPTVVA-YNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLR 293
Query: 279 SSFADISNLLQIEPRNGPAQKLRQEVKQNL 308
+ D+S +L +EP N A+K EV+++L
Sbjct: 294 EATEDLSKVLDVEPDNDLAKKTLSEVERDL 323
Score = 63.9 bits (154), Expect = 2e-10
Identities = 51/196 (26%), Positives = 82/196 (41%), Gaps = 13/196 (6%)
Query: 16 GNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCIKDCT 75
GNE+F +G Y EA Y R++ L V Y+NRA +K N +DC
Sbjct: 216 GNEAFNSGDYEEAVMYYTRSISALPTV---------VAYNNRAQAEIKLQNWNSAFQDCE 266
Query: 76 SALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTRALMDS 135
L L P ++K LLRRA+ Y+ K A D VL ++ + A + ++ + R L +S
Sbjct: 267 KVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVERDLKNS 326
Query: 136 -LGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTATKNRVPS---AGDVE 191
E + K + + + + H++ K A R G+++
Sbjct: 327 EAASETQTKGKRMVIQEIENSEDEEGKSGRKHEDGGGDKKPAEPAGAARAAQPCVMGNIQ 386
Query: 192 KARVLKEEGNELVKKG 207
K K EG + +G
Sbjct: 387 KKLTGKAEGGKRPARG 402
>gi|27262636 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 270 bits (690), Expect = 1e-72
Identities = 145/299 (48%), Positives = 199/299 (66%), Gaps = 8/299 (2%)
Query: 12 LRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCI 71
L++ GNE FR+GQ+AEA+ Y A+ +L+ GS ++ S+LYSNRAAC+LK+GNC CI
Sbjct: 448 LKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDLSILYSNRAACYLKEGNCSGCI 507
Query: 72 KDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTRA 131
+DC AL L PFS+KPLLRRA AYE LE+Y AYVDYKTVLQID + A + +NR++R
Sbjct: 508 QDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQIDCGLQLANDSVNRLSRI 567
Query: 132 LMDSLGPEWRLKLPSIPLVPVSAQ-KRWNSLPSENHKEMAKSKSKETTATKNRVPSAGDV 190
LM+ GP WR KL IP VP S + W+ KEM ++ ++++ +R D
Sbjct: 568 LMELDGPNWREKLSPIPAVPASVPLQAWHPA-----KEMISKQAGDSSS--HRQQGITDE 620
Query: 191 EKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDC 250
+ + LKEEGN+ V N+K A+ KYSE L +N E A Y+NRALCYL L Q+ EA +DC
Sbjct: 621 KTFKALKEEGNQCVNDKNYKDALSKYSECLKINNKECAIYTNRALCYLKLCQFEEAKQDC 680
Query: 251 TEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQNLH 309
+AL+L NVKAFYRRA AHK LK+Y+ S D++ ++ ++P A+ +EV + L+
Sbjct: 681 DQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILLDPSIIEAKMELEEVTRLLN 739
Score = 78.2 bits (191), Expect = 9e-15
Identities = 47/150 (31%), Positives = 80/150 (53%), Gaps = 6/150 (4%)
Query: 164 ENHKEMAKSKSKETTATKNRVPSAGDVEKARVL-----KEEGNELVKKGNHKKAIEKYSE 218
E++KE + + R+ +AG EK + KE+GNE G++++A+ Y+
Sbjct: 175 EDYKEKTVIDKSHLSKIETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTR 234
Query: 219 SLLCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYK 278
S+ A Y+NRA + L+ + A +DC + L+L+ NVKA RRA +K +
Sbjct: 235 SISALPTVVA-YNNRAQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLR 293
Query: 279 SSFADISNLLQIEPRNGPAQKLRQEVKQNL 308
+ D+S +L +EP N A+K EV+++L
Sbjct: 294 EATEDLSKVLDVEPDNDLAKKTLSEVERDL 323
Score = 63.9 bits (154), Expect = 2e-10
Identities = 51/196 (26%), Positives = 82/196 (41%), Gaps = 13/196 (6%)
Query: 16 GNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCIKDCT 75
GNE+F +G Y EA Y R++ L V Y+NRA +K N +DC
Sbjct: 216 GNEAFNSGDYEEAVMYYTRSISALPTV---------VAYNNRAQAEIKLQNWNSAFQDCE 266
Query: 76 SALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTRALMDS 135
L L P ++K LLRRA+ Y+ K A D VL ++ + A + ++ + R L +S
Sbjct: 267 KVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDLAKKTLSEVERDLKNS 326
Query: 136 -LGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTATKNRVPS---AGDVE 191
E + K + + + + H++ K A R G+++
Sbjct: 327 EAASETQTKGKRMVIQEIENSEDEEGKSGRKHEDGGGDKKPAEPAGAARAAQPCVMGNIQ 386
Query: 192 KARVLKEEGNELVKKG 207
K K EG + +G
Sbjct: 387 KKLTGKAEGGKRPARG 402
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 114 bits (286), Expect = 8e-26
Identities = 85/297 (28%), Positives = 137/297 (46%), Gaps = 35/297 (11%)
Query: 12 LRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCI 71
L+ GN+ F+ G+Y EA Y + + +DP VL +NRA+ + +
Sbjct: 136 LKEKGNKYFKQGKYDEAIDCYTKGM-------DADPYNP-VLPTNRASAYFRLKKFAVAE 187
Query: 72 KDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTRA 131
DC A+AL K RR +A AL+K A DY+ VL+++ N A + ++++A
Sbjct: 188 SDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQA 247
Query: 132 LMDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTATKNRVPSAGDVE 191
L + NS P E A K T + ++ + + +
Sbjct: 248 LAS----------------------KENSYPKE-----ADIVIKSTEGERKQIEAQQNKQ 280
Query: 192 KARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDCT 251
+A K+ GN K+G +++AIE Y+ + + +NRA+ YL +++Y EA KDCT
Sbjct: 281 QAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCT 340
Query: 252 EALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQNL 308
+A+ LDG KAF RR A L + D +L +EP N A ++K+ L
Sbjct: 341 QAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKEL 397
Score = 71.6 bits (174), Expect = 8e-13
Identities = 40/120 (33%), Positives = 65/120 (54%)
Query: 189 DVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVK 248
D +KA VLKE+GN+ K+G + +AI+ Y++ + +NRA Y LK++ A
Sbjct: 129 DSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAES 188
Query: 249 DCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQNL 308
DC A+ L+ KA+ RR A AL+ + + D +L++EP N A +++ Q L
Sbjct: 189 DCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQAL 248
Score = 50.4 bits (119), Expect = 2e-06
Identities = 36/119 (30%), Positives = 59/119 (49%), Gaps = 8/119 (6%)
Query: 16 GNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCIKDCT 75
GN F+ G+Y A Y R + A G++ ++L +NRA +LK + KDCT
Sbjct: 289 GNGFFKEGKYERAIECYTRGIA---ADGAN-----ALLPANRAMAYLKIQKYEEAEKDCT 340
Query: 76 SALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTRALMD 134
A+ L K RR +A L K A D++TVL ++ AV ++++ + L++
Sbjct: 341 QAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE 399
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 113 bits (282), Expect = 2e-25
Identities = 84/295 (28%), Positives = 136/295 (46%), Gaps = 35/295 (11%)
Query: 12 LRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCI 71
L+ GN+ F+ G+Y EA Y + + +DP VL +NRA+ + +
Sbjct: 136 LKEKGNKYFKQGKYDEAIDCYTKGM-------DADPYNP-VLPTNRASAYFRLKKFAVAE 187
Query: 72 KDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTRA 131
DC A+AL K RR +A AL+K A DY+ VL+++ N A + ++++A
Sbjct: 188 SDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQA 247
Query: 132 LMDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTATKNRVPSAGDVE 191
L + NS P E A K T + ++ + + +
Sbjct: 248 LAS----------------------KENSYPKE-----ADIVIKSTEGERKQIEAQQNKQ 280
Query: 192 KARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDCT 251
+A K+ GN K+G +++AIE Y+ + + +NRA+ YL +++Y EA KDCT
Sbjct: 281 QAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCT 340
Query: 252 EALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQ 306
+A+ LDG KAF RR A L + D +L +EP N A ++K+
Sbjct: 341 QAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKK 395
Score = 71.6 bits (174), Expect = 8e-13
Identities = 40/120 (33%), Positives = 65/120 (54%)
Query: 189 DVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVK 248
D +KA VLKE+GN+ K+G + +AI+ Y++ + +NRA Y LK++ A
Sbjct: 129 DSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAES 188
Query: 249 DCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQNL 308
DC A+ L+ KA+ RR A AL+ + + D +L++EP N A +++ Q L
Sbjct: 189 DCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQAL 248
>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
sapiens]
Length = 506
Score = 103 bits (257), Expect = 2e-22
Identities = 74/257 (28%), Positives = 119/257 (46%), Gaps = 27/257 (10%)
Query: 52 VLYSNRAACHLKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTV 111
VL +NRA+ + + DC A+AL K RR +A AL+K A DY+ V
Sbjct: 9 VLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERV 68
Query: 112 LQIDDNVTSAVEGINRMTRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAK 171
L+++ N A + ++++AL + NS P E A
Sbjct: 69 LELEPNNFEATNELRKISQALAS----------------------KENSYPKE-----AD 101
Query: 172 SKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYS 231
K T + ++ + + ++A K+ GN K+G +++AIE Y+ + + +
Sbjct: 102 IVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLPA 161
Query: 232 NRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIE 291
NRA+ YL +++Y EA KDCT+A+ LDG KAF RR A L + D +L +E
Sbjct: 162 NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLE 221
Query: 292 PRNGPAQKLRQEVKQNL 308
P N A ++K+ L
Sbjct: 222 PGNKQAVTELSKIKKEL 238
Score = 50.4 bits (119), Expect = 2e-06
Identities = 36/119 (30%), Positives = 59/119 (49%), Gaps = 8/119 (6%)
Query: 16 GNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCIKDCT 75
GN F+ G+Y A Y R + A G++ ++L +NRA +LK + KDCT
Sbjct: 130 GNGFFKEGKYERAIECYTRGIA---ADGAN-----ALLPANRAMAYLKIQKYEEAEKDCT 181
Query: 76 SALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTRALMD 134
A+ L K RR +A L K A D++TVL ++ AV ++++ + L++
Sbjct: 182 QAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKELIE 240
>gi|4507711 tetratricopeptide repeat domain 1 [Homo sapiens]
Length = 292
Score = 84.3 bits (207), Expect = 1e-16
Identities = 46/121 (38%), Positives = 67/121 (55%), Gaps = 3/121 (2%)
Query: 12 LRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCI 71
L+ GNE F+ G Y EA + Y RAL + S +E S+L+SNRAA +K I
Sbjct: 119 LKEEGNEQFKKGDYIEAESSYSRALEMCP---SCFQKERSILFSNRAAARMKQDKKEMAI 175
Query: 72 KDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTRA 131
DC+ A+ L P I+ +LRRA YE +K A DYK++L+ D ++ A E R+ +
Sbjct: 176 NDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLPKQ 235
Query: 132 L 132
+
Sbjct: 236 I 236
Score = 58.2 bits (139), Expect = 9e-09
Identities = 33/107 (30%), Positives = 60/107 (56%), Gaps = 5/107 (4%)
Query: 191 EKARVLKEEGNELVKKGNHKKAIEKYSESL-LCSNL----ESATYSNRALCYLVLKQYTE 245
E++ LKEEGNE KKG++ +A YS +L +C + S +SNRA + +
Sbjct: 114 EESTRLKEEGNEQFKKGDYIEAESSYSRALEMCPSCFQKERSILFSNRAAARMKQDKKEM 173
Query: 246 AVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEP 292
A+ DC++A++L+ ++A RRA+ ++ + D ++L+ +P
Sbjct: 174 AINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDP 220
>gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens]
Length = 705
Score = 77.8 bits (190), Expect = 1e-14
Identities = 53/159 (33%), Positives = 78/159 (49%), Gaps = 11/159 (6%)
Query: 151 PVSAQKRWNSLPSENHKEMAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHK 210
P +A K + SE + +KE + D LKE+GNE +GN++
Sbjct: 69 PQTAMKSAEEINSEAFLASVEKDAKERAKRRRENKVLADA-----LKEKGNEAFAEGNYE 123
Query: 211 KAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQA 270
AI +YSE L Y+NRA Y+ L+ Y +A+ DC ALK D K KA++ +A
Sbjct: 124 TAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKALVDCEWALKCDEKCTKAYFHMGKA 183
Query: 271 HKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQNLH 309
+ ALK+Y S +L+I P KL+ +VK L+
Sbjct: 184 NLALKNYSVSRECYKKILEINP------KLQTQVKGYLN 216
Score = 50.1 bits (118), Expect = 3e-06
Identities = 33/115 (28%), Positives = 52/115 (45%), Gaps = 8/115 (6%)
Query: 10 EELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRD 69
+ L+ GNE+F G Y A Y L L+ + VLY+NRA ++K +
Sbjct: 107 DALKEKGNEAFAEGNYETAILRYSEGLEKLK--------DMKVLYTNRAQAYMKLEDYEK 158
Query: 70 CIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEG 124
+ DC AL K A AL+ Y ++ YK +L+I+ + + V+G
Sbjct: 159 ALVDCEWALKCDEKCTKAYFHMGKANLALKNYSVSRECYKKILEINPKLQTQVKG 213
>gi|4503729 FK506 binding protein 52 [Homo sapiens]
Length = 459
Score = 76.3 bits (186), Expect = 3e-14
Identities = 44/152 (28%), Positives = 78/152 (51%), Gaps = 15/152 (9%)
Query: 162 PSENHKEMAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLL 221
P+ K KS E + S +E++ ++KE G K+G +K+A+ +Y + +
Sbjct: 239 PNAELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVS 298
Query: 222 CSNLES---------------ATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYR 266
ES A++ N A+C+L L+ ++ A++ C +AL+LD N K +R
Sbjct: 299 WLEYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFR 358
Query: 267 RAQAHKALKDYKSSFADISNLLQIEPRNGPAQ 298
R +AH A+ D++ + AD +LQ+ P N A+
Sbjct: 359 RGEAHLAVNDFELARADFQKVLQLYPNNKAAK 390
Score = 50.8 bits (120), Expect = 1e-06
Identities = 44/183 (24%), Positives = 76/183 (41%), Gaps = 10/183 (5%)
Query: 12 LRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEES-------VLYSNRAACHLKD 64
++ G F+ G+Y +A Y + + L+ + S EE + N A CHLK
Sbjct: 273 VKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRLASHLNLAMCHLKL 332
Query: 65 GNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEG 124
I+ C AL L + K L RR A+ A+ + +A D++ VLQ+ N +A
Sbjct: 333 QAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQLYPNNKAAKTQ 392
Query: 125 INRMTRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENH---KEMAKSKSKETTATK 181
+ + + L E +L + K S +H EM + + T ++
Sbjct: 393 LAVCQQRIRRQLAREKKLYANMFERLAEEENKAKAEASSGDHPTDTEMKEEQKSNTAGSQ 452
Query: 182 NRV 184
++V
Sbjct: 453 SQV 455
>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
Length = 499
Score = 76.3 bits (186), Expect = 3e-14
Identities = 40/138 (28%), Positives = 80/138 (57%), Gaps = 3/138 (2%)
Query: 169 MAKSKSKETTAT---KNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNL 225
MA ++ + T ++ P+ G +++A LK + N+ K +++ AI+ YS+++ +
Sbjct: 1 MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPS 60
Query: 226 ESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADIS 285
+ Y NR+L YL + Y A+ D T A++LD K +K +YRRA ++ AL ++++ D
Sbjct: 61 NAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYE 120
Query: 286 NLLQIEPRNGPAQKLRQE 303
+++++P + A+ QE
Sbjct: 121 TVVKVKPHDKDAKMKYQE 138
Score = 45.8 bits (107), Expect = 5e-05
Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 8/105 (7%)
Query: 10 EELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRD 69
EEL+ N+ F+ Y A Y +A+ + + ++ Y NR+ +L+
Sbjct: 29 EELKTQANDYFKAKDYENAIKFYSQAIELNPSN--------AIYYGNRSLAYLRTECYGY 80
Query: 70 CIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQI 114
+ D T A+ L IK RRA++ AL K+ A DY+TV+++
Sbjct: 81 ALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKV 125
>gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 75.1 bits (183), Expect = 7e-14
Identities = 44/147 (29%), Positives = 74/147 (50%), Gaps = 21/147 (14%)
Query: 167 KEMAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYS--------- 217
K K+K TK ++ E+A ++KE+G K G + +A+ +Y
Sbjct: 248 KSFEKAKESWEMDTKEKL------EQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEME 301
Query: 218 ------ESLLCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAH 271
ES + A + N A+CYL L++YT+AV+ C +AL LD N K YRR +A
Sbjct: 302 YGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQ 361
Query: 272 KALKDYKSSFADISNLLQIEPRNGPAQ 298
+ +++S+ D +L++ P+N A+
Sbjct: 362 LLMNEFESAKGDFEKVLEVNPQNKAAR 388
Score = 43.5 bits (101), Expect = 2e-04
Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 7/111 (6%)
Query: 12 LRAAGNESFRNGQYAEASALYGRALRVLQAQ-GSSDPEEES------VLYSNRAACHLKD 64
++ G F+ G+Y +A YG+ + L+ + G S+ E ++ + N A C+LK
Sbjct: 271 VKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKL 330
Query: 65 GNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQID 115
++ C AL L + K L RR A + ++ A D++ VL+++
Sbjct: 331 REYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVN 381
>gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 75.1 bits (183), Expect = 7e-14
Identities = 44/147 (29%), Positives = 74/147 (50%), Gaps = 21/147 (14%)
Query: 167 KEMAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYS--------- 217
K K+K TK ++ E+A ++KE+G K G + +A+ +Y
Sbjct: 248 KSFEKAKESWEMDTKEKL------EQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEME 301
Query: 218 ------ESLLCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAH 271
ES + A + N A+CYL L++YT+AV+ C +AL LD N K YRR +A
Sbjct: 302 YGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQ 361
Query: 272 KALKDYKSSFADISNLLQIEPRNGPAQ 298
+ +++S+ D +L++ P+N A+
Sbjct: 362 LLMNEFESAKGDFEKVLEVNPQNKAAR 388
Score = 43.5 bits (101), Expect = 2e-04
Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 7/111 (6%)
Query: 12 LRAAGNESFRNGQYAEASALYGRALRVLQAQ-GSSDPEEES------VLYSNRAACHLKD 64
++ G F+ G+Y +A YG+ + L+ + G S+ E ++ + N A C+LK
Sbjct: 271 VKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKL 330
Query: 65 GNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQID 115
++ C AL L + K L RR A + ++ A D++ VL+++
Sbjct: 331 REYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVN 381
>gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 75.1 bits (183), Expect = 7e-14
Identities = 44/147 (29%), Positives = 74/147 (50%), Gaps = 21/147 (14%)
Query: 167 KEMAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYS--------- 217
K K+K TK ++ E+A ++KE+G K G + +A+ +Y
Sbjct: 248 KSFEKAKESWEMDTKEKL------EQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEME 301
Query: 218 ------ESLLCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAH 271
ES + A + N A+CYL L++YT+AV+ C +AL LD N K YRR +A
Sbjct: 302 YGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQ 361
Query: 272 KALKDYKSSFADISNLLQIEPRNGPAQ 298
+ +++S+ D +L++ P+N A+
Sbjct: 362 LLMNEFESAKGDFEKVLEVNPQNKAAR 388
Score = 43.5 bits (101), Expect = 2e-04
Identities = 29/111 (26%), Positives = 54/111 (48%), Gaps = 7/111 (6%)
Query: 12 LRAAGNESFRNGQYAEASALYGRALRVLQAQ-GSSDPEEES------VLYSNRAACHLKD 64
++ G F+ G+Y +A YG+ + L+ + G S+ E ++ + N A C+LK
Sbjct: 271 VKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKL 330
Query: 65 GNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQID 115
++ C AL L + K L RR A + ++ A D++ VL+++
Sbjct: 331 REYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVN 381
>gi|29725607 smooth muscle cell associated protein-1 isoform 2 [Homo
sapiens]
Length = 944
Score = 72.8 bits (177), Expect = 4e-13
Identities = 44/135 (32%), Positives = 76/135 (56%), Gaps = 10/135 (7%)
Query: 177 TTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESL---LCSNLESATYSNR 233
T + P A VE+ L++EGNEL K G++ A+ Y+++L ++ + NR
Sbjct: 8 TPEPRPATPGASSVEQ---LRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNR 64
Query: 234 ALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPR 293
A C+L L+ Y +A + ++A++ DG +VKA YRR+QA + L + D+ + +EP+
Sbjct: 65 AACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPK 124
Query: 294 NGPAQKLRQEVKQNL 308
N K+ QE +N+
Sbjct: 125 N----KVFQEALRNI 135
Score = 64.7 bits (156), Expect = 1e-10
Identities = 52/202 (25%), Positives = 97/202 (48%), Gaps = 22/202 (10%)
Query: 8 SVEELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNC 67
SVE+LR GNE F+ G Y A A Y +AL + + P++++VL+ NRAACHLK +
Sbjct: 20 SVEQLRKEGNELFKCGDYGGALAAYTQALGL-----DATPQDQAVLHRNRAACHLKLEDY 74
Query: 68 RDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINR 127
+ + A+ +K L RR+ A E L + A +D + + ++ N+
Sbjct: 75 DKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPK--------NK 126
Query: 128 MTRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSL--PSENHKEMAKSKSKETTATKNRVP 185
+ + + ++G + + K+ + ++ + L P E K K+ A++N V
Sbjct: 127 VFQEALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEE------KGTEKKQKASQNLVV 180
Query: 186 SA-GDVEKARVLKEEGNELVKK 206
A D ++ + G +L+++
Sbjct: 181 LAREDAGAEKIFRSNGVQLLQR 202
>gi|54607135 translocase of outer mitochondrial membrane 70 homolog
A [Homo sapiens]
Length = 608
Score = 72.4 bits (176), Expect = 5e-13
Identities = 38/107 (35%), Positives = 71/107 (66%), Gaps = 5/107 (4%)
Query: 190 VEKARVLKEEGNELVKKGNHKKAIEKYSESL-LC---SNLESAT-YSNRALCYLVLKQYT 244
+++A+ K +GN+ K G +++AI+ Y+E++ LC N++ +T Y NRA + L+++
Sbjct: 111 LDRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDLSTFYQNRAAAFEQLQKWK 170
Query: 245 EAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIE 291
E +DCT+A++L+ K VKA +RRA+AH+ L + K D++ + +E
Sbjct: 171 EVAQDCTKAVELNPKYVKALFRRAKAHEKLDNKKECLEDVTAVCILE 217
Score = 60.1 bits (144), Expect = 2e-09
Identities = 78/317 (24%), Positives = 133/317 (41%), Gaps = 35/317 (11%)
Query: 7 DSVEELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGN 66
D + + GN+ F+ G+Y +A Y A+ + + + D S Y NRAA +
Sbjct: 112 DRAQAAKNKGNKYFKAGKYEQAIQCYTEAISLCPTEKNVDL---STFYQNRAAAFEQLQK 168
Query: 67 CRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGI- 125
++ +DCT A+ L P +K L RRA A+E L D K D +EG
Sbjct: 169 WKEVAQDCTKAVELNPKYVKALFRRAKAHEKL--------DNKKECLEDVTAVCILEGFQ 220
Query: 126 NRMTRALMDS----LGPE-----WRLKLPSIPLVPVSAQ--KRWNSLPSENHKEMAKSKS 174
N+ + L D LG E ++ + P +P S Q K + S +++ K
Sbjct: 221 NQQSMLLADKVLKLLGKEKAKEKYKNREPLMP----SPQFIKSYFSSFTDDIISQPMLKG 276
Query: 175 KETTATKNRVPSAGDV-EKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESA-TYSN 232
+++ K++ A +V E + LK + +++ N+ K I + S+ + A
Sbjct: 277 EKSDEDKDKEGEALEVKENSGYLK--AKQYMEEENYDKIISECSKEIDAEGKYMAEALLL 334
Query: 233 RALCYLVLKQYTEAVKDCTEALKLDGKNVK----AFYRRAQAHKALKDYKSSFADISNLL 288
RA YL++ A D + + L NVK A +R + + S D +
Sbjct: 335 RATFYLLIGNANAAKPDLDKVISLKEANVKLRANALIKRGSMYMQQQQPLLSTQDFNMAA 394
Query: 289 QIEPRNGPAQKLRQEVK 305
I+P+N R ++K
Sbjct: 395 DIDPQNADVYHHRGQLK 411
>gi|24308141 small glutamine-rich tetratricopeptide repeat
(TPR)-containing, beta [Homo sapiens]
Length = 304
Score = 71.6 bits (174), Expect = 8e-13
Identities = 39/113 (34%), Positives = 61/113 (53%), Gaps = 2/113 (1%)
Query: 182 NRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLK 241
N VP DV KA LK+EGN +K+ N+ A++ Y++++ + Y NRA L
Sbjct: 76 NSVPE--DVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLG 133
Query: 242 QYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRN 294
YT+A+KDC +A+ +D K KA+ R A AL ++ + L ++P N
Sbjct: 134 HYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPEN 186
Score = 52.8 bits (125), Expect = 4e-07
Identities = 36/113 (31%), Positives = 51/113 (45%), Gaps = 8/113 (7%)
Query: 3 PKFPDSVEELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHL 62
P+ ++L+ GN + YA A Y +A+ + DP +V Y NRAA
Sbjct: 79 PEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIEL-------DPNN-AVYYCNRAAAQS 130
Query: 63 KDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQID 115
K G+ D IKDC A+A+ K R A AL K+ A Y+ L +D
Sbjct: 131 KLGHYTDAIKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLD 183
>gi|89179321 smooth muscle cell associated protein-1 isoform 3 [Homo
sapiens]
Length = 929
Score = 70.1 bits (170), Expect = 2e-12
Identities = 42/126 (33%), Positives = 74/126 (58%), Gaps = 10/126 (7%)
Query: 186 SAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESL---LCSNLESATYSNRALCYLVLKQ 242
+A VE+ L++EGNEL K G++ A+ Y+++L ++ + NRA C+L L+
Sbjct: 2 TASSVEQ---LRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLED 58
Query: 243 YTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQ 302
Y +A + ++A++ DG +VKA YRR+QA + L + D+ + +EP+N K+ Q
Sbjct: 59 YDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKN----KVFQ 114
Query: 303 EVKQNL 308
E +N+
Sbjct: 115 EALRNI 120
Score = 64.7 bits (156), Expect = 1e-10
Identities = 52/202 (25%), Positives = 97/202 (48%), Gaps = 22/202 (10%)
Query: 8 SVEELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNC 67
SVE+LR GNE F+ G Y A A Y +AL + + P++++VL+ NRAACHLK +
Sbjct: 5 SVEQLRKEGNELFKCGDYGGALAAYTQALGL-----DATPQDQAVLHRNRAACHLKLEDY 59
Query: 68 RDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINR 127
+ + A+ +K L RR+ A E L + A +D + + ++ N+
Sbjct: 60 DKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPK--------NK 111
Query: 128 MTRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSL--PSENHKEMAKSKSKETTATKNRVP 185
+ + + ++G + + K+ + ++ + L P E K K+ A++N V
Sbjct: 112 VFQEALRNIGGQIQEKVRYMSSTDAKVEQMFQILLDPEE------KGTEKKQKASQNLVV 165
Query: 186 SA-GDVEKARVLKEEGNELVKK 206
A D ++ + G +L+++
Sbjct: 166 LAREDAGAEKIFRSNGVQLLQR 187
>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
protein) [Homo sapiens]
Length = 543
Score = 69.7 bits (169), Expect = 3e-12
Identities = 32/95 (33%), Positives = 59/95 (62%)
Query: 197 KEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKL 256
K +GNE +KG++ +A++ Y+E++ + ++ YSNRA CY L ++ A+KDC E ++L
Sbjct: 364 KNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEECIQL 423
Query: 257 DGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIE 291
+ +K + R+A A +A+KDY + L ++
Sbjct: 424 EPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLD 458
Score = 69.3 bits (168), Expect = 4e-12
Identities = 43/126 (34%), Positives = 63/126 (50%), Gaps = 8/126 (6%)
Query: 6 PDSVEELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDG 65
PD E + GNE F+ G Y +A Y A++ +P++ LYSNRAAC+ K
Sbjct: 357 PDLALEEKNKGNECFQKGDYPQAMKHYTEAIK-------RNPKDAK-LYSNRAACYTKLL 408
Query: 66 NCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGI 125
+ +KDC + L P IK R+A+A EA++ Y A Y+ L +D + A +G
Sbjct: 409 EFQLALKDCEECIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSSCKEAADGY 468
Query: 126 NRMTRA 131
R A
Sbjct: 469 QRCMMA 474
Score = 51.6 bits (122), Expect = 9e-07
Identities = 66/310 (21%), Positives = 119/310 (38%), Gaps = 53/310 (17%)
Query: 7 DSVEELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGN 66
+ V EL+ GN++ G +A Y A+++ DP VLYSNR+A + K G+
Sbjct: 2 EQVNELKEKGNKALSVGNIDDALQCYSEAIKL-------DPHNH-VLYSNRSAAYAKKGD 53
Query: 67 CRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGIN 126
+ +D + L P K R+A+A E L ++ A Y+ L+ + N EG+
Sbjct: 54 YQKAYEDGCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKEGLQ 113
Query: 127 RM-----TRALMDSLG-PEWRLKLPSIPLVPVSAQ--------KRWNSLPSENHK----- 167
M R M+ P KL S P ++ + PS+
Sbjct: 114 NMEARLAERKFMNPFNMPNLYQKLESDPRTRTLLSDPTYRELIEQLRNKPSDLGTKLQDP 173
Query: 168 ------------EMAKSKSKETTATKNRVPSAGDVEKARVLKEE--------------GN 201
++ +E AT P K ++E+ GN
Sbjct: 174 RIMTTLSVLLGVDLGSMDEEEEIATPPPPPPPKKETKPEPMEEDLPENKKQALKEKELGN 233
Query: 202 ELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNV 261
+ KK + A++ Y ++ +N+A Y Y + + C +A+++ +N
Sbjct: 234 DAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRENR 293
Query: 262 KAFYRRAQAH 271
+ + + A+A+
Sbjct: 294 EDYRQIAKAY 303
Score = 46.2 bits (108), Expect = 4e-05
Identities = 31/119 (26%), Positives = 56/119 (47%)
Query: 190 VEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKD 249
+E+ LKE+GN+ + GN A++ YSE++ YSNR+ Y Y +A +D
Sbjct: 1 MEQVNELKEKGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYED 60
Query: 250 CTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQNL 308
+ + L K + R+A A + L ++ + L+ E N ++ Q ++ L
Sbjct: 61 GCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKEGLQNMEARL 119
Score = 41.6 bits (96), Expect = 0.001
Identities = 32/126 (25%), Positives = 52/126 (41%), Gaps = 26/126 (20%)
Query: 193 ARVLKEEGNELVKKGNHKKAIEKYSESLL----------CSNLESATYSNRALCY----L 238
A+ GN K+ +K AI Y++SL C E L Y L
Sbjct: 300 AKAYARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQERLAYINPDL 359
Query: 239 VLKQ------------YTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISN 286
L++ Y +A+K TEA+K + K+ K + RA + L +++ + D
Sbjct: 360 ALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEE 419
Query: 287 LLQIEP 292
+Q+EP
Sbjct: 420 CIQLEP 425
>gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens]
Length = 929
Score = 69.3 bits (168), Expect = 4e-12
Identities = 37/116 (31%), Positives = 62/116 (53%), Gaps = 3/116 (2%)
Query: 196 LKEEGNELVKKGNHKKAIEKYSESLLCSN---LESATYSNRALCYLVLKQYTEAVKDCTE 252
LKEEGN + ++K A YS++L + L + Y NRA C L + Y +A D +
Sbjct: 9 LKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQAASDASR 68
Query: 253 ALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQNL 308
A+ ++ ++KA YRR QA + L +F D+ +EPRN Q++ + + ++
Sbjct: 69 AIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNTSI 124
Score = 52.8 bits (125), Expect = 4e-07
Identities = 35/126 (27%), Positives = 58/126 (46%), Gaps = 5/126 (3%)
Query: 11 ELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDC 70
+L+ GN F+ Y A+ Y +AL++ + D + LY NRAAC LK +
Sbjct: 8 QLKEEGNRHFQLQDYKAATNSYSQALKL-----TKDKALLATLYRNRAACGLKTESYVQA 62
Query: 71 IKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTR 130
D + A+ + IK L RR A E L K A+ D + ++ + E + R+
Sbjct: 63 ASDASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNT 122
Query: 131 ALMDSL 136
++ + L
Sbjct: 123 SIQEKL 128
>gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens]
Length = 931
Score = 69.3 bits (168), Expect = 4e-12
Identities = 37/116 (31%), Positives = 62/116 (53%), Gaps = 3/116 (2%)
Query: 196 LKEEGNELVKKGNHKKAIEKYSESLLCSN---LESATYSNRALCYLVLKQYTEAVKDCTE 252
LKEEGN + ++K A YS++L + L + Y NRA C L + Y +A D +
Sbjct: 9 LKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQAASDASR 68
Query: 253 ALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQNL 308
A+ ++ ++KA YRR QA + L +F D+ +EPRN Q++ + + ++
Sbjct: 69 AIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNTSI 124
Score = 52.8 bits (125), Expect = 4e-07
Identities = 35/126 (27%), Positives = 58/126 (46%), Gaps = 5/126 (3%)
Query: 11 ELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDC 70
+L+ GN F+ Y A+ Y +AL++ + D + LY NRAAC LK +
Sbjct: 8 QLKEEGNRHFQLQDYKAATNSYSQALKL-----TKDKALLATLYRNRAACGLKTESYVQA 62
Query: 71 IKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMTR 130
D + A+ + IK L RR A E L K A+ D + ++ + E + R+
Sbjct: 63 ASDASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATLEPRNQNFQEMLRRLNT 122
Query: 131 ALMDSL 136
++ + L
Sbjct: 123 SIQEKL 128
>gi|56181387 STIP1 homology and U-box containing protein 1 [Homo
sapiens]
Length = 303
Score = 68.2 bits (165), Expect = 9e-12
Identities = 33/92 (35%), Positives = 56/92 (60%)
Query: 193 ARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDCTE 252
A+ LKE+GN L + +A Y ++ + L + Y+NRALCYL ++Q+ +A+ DC
Sbjct: 26 AQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRR 85
Query: 253 ALKLDGKNVKAFYRRAQAHKALKDYKSSFADI 284
AL+LDG++VKA + Q ++ Y + A++
Sbjct: 86 ALELDGQSVKAHFFLGQCQLEMESYDEAIANL 117
Score = 53.1 bits (126), Expect = 3e-07
Identities = 51/170 (30%), Positives = 73/170 (42%), Gaps = 33/170 (19%)
Query: 2 APKFPDSVEELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACH 61
+P+ S +EL+ GN F +Y EA+A YGRA+ + +P +V Y+NRA C+
Sbjct: 19 SPEKSPSAQELKEQGNRLFVGRKYPEAAACYGRAI-------TRNP-LVAVYYTNRALCY 70
Query: 62 LKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSA 121
LK + DC AL L S+K +E Y
Sbjct: 71 LKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYD------------------- 111
Query: 122 VEGINRMTRALMDSLGPEWRLKL-PSIP-LVPVSAQKRWNSLPSEN-HKE 168
E I + RA SL E RL IP + ++ +KRWNS+ H+E
Sbjct: 112 -EAIANLQRAY--SLAKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQE 158
>gi|17149853 WAF-1/CIP1 stabilizing protein 39 [Homo sapiens]
Length = 349
Score = 68.2 bits (165), Expect = 9e-12
Identities = 45/118 (38%), Positives = 57/118 (48%)
Query: 11 ELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDC 70
E RA G E FR G A+ YGRALR+L P E +VL++N AAC L G +
Sbjct: 212 EERARGTELFRAGNPEGAARCYGRALRLLLTLPPPGPPERTVLHANLAACQLLLGQPQLA 271
Query: 71 IKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRM 128
+ C L P +K L RR A AL A D K VL ID +A E + ++
Sbjct: 272 AQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKV 329
Score = 55.8 bits (133), Expect = 5e-08
Identities = 39/120 (32%), Positives = 61/120 (50%), Gaps = 11/120 (9%)
Query: 191 EKARVLKEE---GNELVKKGNHKKAIEKYSESL-LCSNL-------ESATYSNRALCYLV 239
EK + +EE G EL + GN + A Y +L L L + ++N A C L+
Sbjct: 205 EKEALAREERARGTELFRAGNPEGAARCYGRALRLLLTLPPPGPPERTVLHANLAACQLL 264
Query: 240 LKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQK 299
L Q A + C L+ + ++KA YRR A AL + + + AD+ +L I+P+N AQ+
Sbjct: 265 LGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQE 324
>gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 2
[Homo sapiens]
Length = 438
Score = 67.8 bits (164), Expect = 1e-11
Identities = 42/137 (30%), Positives = 66/137 (48%), Gaps = 11/137 (8%)
Query: 169 MAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCS----N 224
MA K A +N + + KE+GN+ K+GN+K A E Y+E+L
Sbjct: 183 MAPDHEKACIACRN-------AKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIK 235
Query: 225 LESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADI 284
+ Y NR L++ +A++DCT A+KLD +KA+ RRAQ + + Y+ + D
Sbjct: 236 TNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDY 295
Query: 285 SNLLQIEPRNGPAQKLR 301
+ Q E Q L+
Sbjct: 296 EKVYQTEKTKEHKQLLK 312
Score = 57.4 bits (137), Expect = 2e-08
Identities = 36/100 (36%), Positives = 51/100 (51%), Gaps = 4/100 (4%)
Query: 16 GNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCIKDCT 75
GN++F+ G Y A LY AL + ++ + + LY NR + K D I+DCT
Sbjct: 207 GNKAFKEGNYKLAYELYTEALGI----DPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCT 262
Query: 76 SALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQID 115
+A+ L IK LRRA Y E+Y A DY+ V Q +
Sbjct: 263 NAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTE 302
Score = 40.0 bits (92), Expect = 0.003
Identities = 18/70 (25%), Positives = 38/70 (54%)
Query: 230 YSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQ 289
Y NRA ++L ++ EA+ D ++++LD V+ R + H +L + ++ L+
Sbjct: 9 YGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALE 68
Query: 290 IEPRNGPAQK 299
++ +N AQ+
Sbjct: 69 LDHKNAQAQQ 78
>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
[Homo sapiens]
Length = 494
Score = 67.8 bits (164), Expect = 1e-11
Identities = 42/137 (30%), Positives = 66/137 (48%), Gaps = 11/137 (8%)
Query: 169 MAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCS----N 224
MA K A +N + + KE+GN+ K+GN+K A E Y+E+L
Sbjct: 239 MAPDHEKACIACRN-------AKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIK 291
Query: 225 LESATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADI 284
+ Y NR L++ +A++DCT A+KLD +KA+ RRAQ + + Y+ + D
Sbjct: 292 TNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDY 351
Query: 285 SNLLQIEPRNGPAQKLR 301
+ Q E Q L+
Sbjct: 352 EKVYQTEKTKEHKQLLK 368
Score = 57.4 bits (137), Expect = 2e-08
Identities = 36/100 (36%), Positives = 51/100 (51%), Gaps = 4/100 (4%)
Query: 16 GNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCIKDCT 75
GN++F+ G Y A LY AL + ++ + + LY NR + K D I+DCT
Sbjct: 263 GNKAFKEGNYKLAYELYTEALGI----DPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCT 318
Query: 76 SALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQID 115
+A+ L IK LRRA Y E+Y A DY+ V Q +
Sbjct: 319 NAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTE 358
Score = 53.5 bits (127), Expect = 2e-07
Identities = 26/108 (24%), Positives = 57/108 (52%)
Query: 192 KARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDCT 251
+A KE+GN K ++ +A Y++++ ++ Y NRA ++L ++ EA+ D
Sbjct: 27 EAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREALGDAQ 86
Query: 252 EALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQK 299
++++LD V+ R + H +L + ++ L+++ +N AQ+
Sbjct: 87 QSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQ 134
Score = 33.9 bits (76), Expect = 0.19
Identities = 60/307 (19%), Positives = 110/307 (35%), Gaps = 36/307 (11%)
Query: 10 EELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRD 69
E + GN + Y EA Y +A+ + S Y NRAA + G R+
Sbjct: 29 ETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNAS--------YYGNRAATLMMLGRFRE 80
Query: 70 CIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEGINRMT 129
+ D ++ L ++ LR + +L A ++ L++D A +
Sbjct: 81 ALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALELDHKNAQAQQEFKNAN 140
Query: 130 RALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENHKEMAKSKSKETTATKNRVPSAG- 188
+ E + V + P+ + ++ K+ E A R P A
Sbjct: 141 AVMEYEKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKA---ECLAMLGRYPEAQS 197
Query: 189 --------DVEKARVLKEEGNELVKKGNHKKAIEKYSESL-LCSNLESATYSNRALCYLV 239
D A L G L + +KA++ + ++L + + E A + R L
Sbjct: 198 VASDILRMDSTNADALYVRGLCLYYEDCIEKAVQFFVQALRMAPDHEKACIACRNAKALK 257
Query: 240 LKQ-----------YTEAVKDCTEALKLDGKNVKA----FYRRAQAHKALKDYKSSFADI 284
K+ Y A + TEAL +D N+K + R + L+ + D
Sbjct: 258 AKKEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDC 317
Query: 285 SNLLQIE 291
+N ++++
Sbjct: 318 TNAVKLD 324
>gi|4826932 peptidylprolyl isomerase D [Homo sapiens]
Length = 370
Score = 65.1 bits (157), Expect = 8e-11
Identities = 44/140 (31%), Positives = 63/140 (45%), Gaps = 20/140 (14%)
Query: 189 DVEKARVLKEE----GNELVKKGNHKKAIEKYSESLLCSNLESATYS------------- 231
DV+K ++ E+ GN K N + AI+KY+E L + A
Sbjct: 215 DVDKILLITEDLKNIGNTFFKSQNWEMAIKKYAEVLRYVDSSKAVIETADRAKLQPIALS 274
Query: 232 ---NRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLL 288
N C L + + A+ C EAL+LD N KA YRRAQ + LK+Y + AD+
Sbjct: 275 CVLNIGACKLKMSNWQGAIDSCLEALELDPSNTKALYRRAQGWQGLKEYDQALADLKKAQ 334
Query: 289 QIEPRNGPAQKLRQEVKQNL 308
I P + Q +VKQ +
Sbjct: 335 GIAPEDKAIQAELLKVKQKI 354
Score = 47.8 bits (112), Expect = 1e-05
Identities = 32/108 (29%), Positives = 50/108 (46%), Gaps = 8/108 (7%)
Query: 10 EELRAAGNESFRNGQYAEASALYGRALRVLQA-----QGSSDPEEESVLYS---NRAACH 61
E+L+ GN F++ + A Y LR + + + + + + + S N AC
Sbjct: 224 EDLKNIGNTFFKSQNWEMAIKKYAEVLRYVDSSKAVIETADRAKLQPIALSCVLNIGACK 283
Query: 62 LKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYK 109
LK N + I C AL L P + K L RRA ++ L++Y A D K
Sbjct: 284 LKMSNWQGAIDSCLEALELDPSNTKALYRRAQGWQGLKEYDQALADLK 331
>gi|201860300 aryl hydrocarbon receptor interacting protein [Homo
sapiens]
Length = 330
Score = 64.7 bits (156), Expect = 1e-10
Identities = 50/175 (28%), Positives = 85/175 (48%), Gaps = 30/175 (17%)
Query: 159 NSLPSENHKEMAKSKSKETTATKNRVPSA-GDVEKAR---VLKEEGNELVKKGNHKKAIE 214
N P H EM K E+ T + P A D EKA+ ++ +EGN L ++G+ K+A
Sbjct: 144 NPQPLIFHMEMLKV---ESPGTYQQDPWAMTDEEKAKAVPLIHQEGNRLYREGHVKEAAA 200
Query: 215 KYSESLLC-SNLE-----------------SATYSNRALCYLVLKQYTEAVKDCTEALKL 256
KY +++ C NL+ + N C LV+++Y E + C+ L
Sbjct: 201 KYYDAIACLKNLQMKEQPGSPEWIQLDQQITPLLLNYCQCKLVVEEYYEVLDHCSSILNK 260
Query: 257 DGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPA-----QKLRQEVKQ 306
NVKA+++R +AH A+ + + + AD + +L+++P P Q L ++Q
Sbjct: 261 YDDNVKAYFKRGKAHAAVWNAQEAQADFAKVLELDPALAPVVSRELQALEARIRQ 315
Score = 36.2 bits (82), Expect = 0.038
Identities = 30/125 (24%), Positives = 52/125 (41%), Gaps = 10/125 (8%)
Query: 8 SVEELRAAGNESFRNGQYAEASALYGRALRVL------QAQGSSD----PEEESVLYSNR 57
+V + GN +R G EA+A Y A+ L + GS + ++ + L N
Sbjct: 178 AVPLIHQEGNRLYREGHVKEAAAKYYDAIACLKNLQMKEQPGSPEWIQLDQQITPLLLNY 237
Query: 58 AACHLKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDN 117
C L + + C+S L ++K +R A+ A+ A D+ VL++D
Sbjct: 238 CQCKLVVEEYYEVLDHCSSILNKYDDNVKAYFKRGKAHAAVWNAQEAQADFAKVLELDPA 297
Query: 118 VTSAV 122
+ V
Sbjct: 298 LAPVV 302
>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
Length = 313
Score = 60.5 bits (145), Expect = 2e-09
Identities = 35/110 (31%), Positives = 55/110 (50%)
Query: 185 PSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYT 244
PS D +A LK EGNE +K N + A+ Y +++ + + + NRA Y L Y
Sbjct: 83 PSEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYA 142
Query: 245 EAVKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRN 294
AV+DC A+ +D KA+ R A +L + + A L+++P N
Sbjct: 143 GAVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDN 192
Score = 52.8 bits (125), Expect = 4e-07
Identities = 35/111 (31%), Positives = 52/111 (46%), Gaps = 9/111 (8%)
Query: 10 EELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRD 69
E L+ GNE + + A YG+A+ + A +V + NRAA + K GN
Sbjct: 92 ERLKTEGNEQMKVENFEAAVHFYGKAIELNPAN--------AVYFCNRAAAYSKLGNYAG 143
Query: 70 CIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQID-DNVT 119
++DC A+ + P K R A +L K+ A YK L++D DN T
Sbjct: 144 AVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPDNET 194
>gi|27881484 zinc finger CCCH-type containing 7B [Homo sapiens]
Length = 977
Score = 58.9 bits (141), Expect = 5e-09
Identities = 36/122 (29%), Positives = 63/122 (51%), Gaps = 12/122 (9%)
Query: 199 EGNELVKKGNHKKAIEKYSESL------------LCSNLESATYSNRALCYLVLKQYTEA 246
EGN+L ++ ++K+A+ +Y E L L L + NRA CY + Y +A
Sbjct: 42 EGNDLFREKDYKQALVQYMEGLNVADYAASDQVALPRELLCKLHVNRAACYFTMGLYEKA 101
Query: 247 VKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLRQEVKQ 306
++D +AL LD ++++A +R+A+A L +K ++ S P + +L QE+ Q
Sbjct: 102 LEDSEKALGLDSESIRALFRKARALNELGRHKEAYECSSRCSLALPHDESVTQLGQELAQ 161
Query: 307 NL 308
L
Sbjct: 162 KL 163
Score = 47.8 bits (112), Expect = 1e-05
Identities = 35/101 (34%), Positives = 46/101 (45%), Gaps = 4/101 (3%)
Query: 9 VEELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSD---PEEESV-LYSNRAACHLKD 64
V+ L A GN+ FR Y +A Y L V S P E L+ NRAAC+
Sbjct: 36 VQNLFAEGNDLFREKDYKQALVQYMEGLNVADYAASDQVALPRELLCKLHVNRAACYFTM 95
Query: 65 GNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAY 105
G ++D AL L SI+ L R+A A L ++ AY
Sbjct: 96 GLYEKALEDSEKALGLDSESIRALFRKARALNELGRHKEAY 136
>gi|156627581 tetratricopeptide repeat domain 4 [Homo sapiens]
Length = 387
Score = 58.2 bits (139), Expect = 9e-09
Identities = 37/115 (32%), Positives = 60/115 (52%), Gaps = 4/115 (3%)
Query: 191 EKARVLKEEGNELVKKGNHKKAIEKYSESL--LCS--NLESATYSNRALCYLVLKQYTEA 246
E+A+ K+EGN+ K+ ++KKA+ Y+E L C+ +L + Y+NRA L + A
Sbjct: 77 EQAKTYKDEGNDYFKEKDYKKAVISYTEGLKKKCADPDLNAVLYTNRAAAQYYLGNFRSA 136
Query: 247 VKDCTEALKLDGKNVKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNGPAQKLR 301
+ D T A KL ++KA R A H LK + + LQI+ + ++R
Sbjct: 137 LNDVTAARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQIDAKEKKLLEMR 191
Score = 50.8 bits (120), Expect = 1e-06
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 4/100 (4%)
Query: 16 GNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRDCIKDCT 75
GN+ F+ Y +A Y L+ + +DP+ +VLY+NRAA GN R + D T
Sbjct: 86 GNDYFKEKDYKKAVISYTEGLK----KKCADPDLNAVLYTNRAAAQYYLGNFRSALNDVT 141
Query: 76 SALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQID 115
+A L P +K ++R A + L+ + A LQID
Sbjct: 142 AARKLKPCHLKAIIRGALCHLELKHFAEAVNWCDEGLQID 181
>gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Homo
sapiens]
Length = 420
Score = 57.4 bits (137), Expect = 2e-08
Identities = 40/122 (32%), Positives = 63/122 (51%), Gaps = 12/122 (9%)
Query: 196 LKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDCTEALK 255
LK++GN+L N+ AI Y+ ++ +N Y NRA C+L LK +A++D ++AL+
Sbjct: 293 LKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAIEDSSKALE 352
Query: 256 L------DGKN--VKAFYRRAQAHKALKDYKSSFADISNLLQIEPRNG----PAQKLRQE 303
L D N +KA RR A L+ Y D L+I+P N A+K+R
Sbjct: 353 LLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKIVQIDAEKIRNV 412
Query: 304 VK 305
++
Sbjct: 413 IQ 414
Score = 51.6 bits (122), Expect = 9e-07
Identities = 39/114 (34%), Positives = 55/114 (48%), Gaps = 16/114 (14%)
Query: 10 EELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACHLKDGNCRD 69
E L+ GN+ F Y A Y A+R+ + +LY NRAACHLK N
Sbjct: 291 EWLKDKGNKLFATENYLAAINAYNLAIRL--------NNKMPLLYLNRAACHLKLKNLHK 342
Query: 70 CIKDCTSALALV--PFS------IKPLLRRASAYEALEKYPMAYVDYKTVLQID 115
I+D + AL L+ P + +K +RR +A+ LE Y DY+ L+ID
Sbjct: 343 AIEDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKID 396
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.127 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,919,415
Number of Sequences: 37866
Number of extensions: 435354
Number of successful extensions: 1552
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 1218
Number of HSP's gapped (non-prelim): 266
length of query: 309
length of database: 18,247,518
effective HSP length: 102
effective length of query: 207
effective length of database: 14,385,186
effective search space: 2977733502
effective search space used: 2977733502
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.