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Search of human proteins with 21361183
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361183 paired-like homeodomain transcription factor 2
isoform c [Homo sapiens]
(324 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361183 paired-like homeodomain transcription factor 2 isofo... 660 0.0
gi|24234708 paired-like homeodomain transcription factor 2 isofo... 527 e-150
gi|24234711 paired-like homeodomain transcription factor 2 isofo... 524 e-149
gi|152963644 paired-like homeodomain transcription factor 1 [Hom... 364 e-101
gi|4826912 paired-like homeodomain 3 [Homo sapiens] 297 7e-81
gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens] 119 4e-27
gi|55743092 aristaless-like homeobox 4 [Homo sapiens] 112 6e-25
gi|24497589 aristaless related homeobox [Homo sapiens] 108 8e-24
gi|122937484 dorsal root ganglia homeobox [Homo sapiens] 105 7e-23
gi|207029223 paired box 7 isoform 3 [Homo sapiens] 104 1e-22
gi|4505619 paired box 7 isoform 1 [Homo sapiens] 103 2e-22
gi|7524359 paired box 7 isoform 2 [Homo sapiens] 103 2e-22
gi|113204604 aristaless-like homeobox 3 [Homo sapiens] 100 2e-21
gi|126116581 retina and anterior neural fold homeobox [Homo sapi... 100 3e-21
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 96 6e-20
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] 96 6e-20
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] 96 6e-20
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] 96 6e-20
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 94 1e-19
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 94 1e-19
gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens] 93 4e-19
gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Hom... 93 4e-19
gi|14149760 orthopedia homeobox [Homo sapiens] 93 4e-19
gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Hom... 93 4e-19
gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens] 92 6e-19
gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo sapi... 92 6e-19
gi|34365783 visual system homeobox 2 [Homo sapiens] 90 3e-18
gi|11056038 visual system homeobox 1 isoform a [Homo sapiens] 89 4e-18
gi|12707580 paired-like homeobox 2b [Homo sapiens] 88 9e-18
gi|20070107 orthodenticle homeobox 1 [Homo sapiens] 87 2e-17
>gi|21361183 paired-like homeodomain transcription factor 2 isoform
c [Homo sapiens]
Length = 324
Score = 660 bits (1703), Expect = 0.0
Identities = 324/324 (100%), Positives = 324/324 (100%)
Query: 1 MNCMKGPLHLEHRAAGTKLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSSKHRLEVHTIS 60
MNCMKGPLHLEHRAAGTKLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSSKHRLEVHTIS
Sbjct: 1 MNCMKGPLHLEHRAAGTKLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSSKHRLEVHTIS 60
Query: 61 DTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMS 120
DTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMS
Sbjct: 61 DTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMS 120
Query: 121 TREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPG 180
TREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPG
Sbjct: 121 TREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPG 180
Query: 181 YSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTG 240
YSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTG
Sbjct: 181 YSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTG 240
Query: 241 VPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSS 300
VPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSS
Sbjct: 241 VPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSS 300
Query: 301 FGYASVQNPASNLSACQYAVDRPV 324
FGYASVQNPASNLSACQYAVDRPV
Sbjct: 301 FGYASVQNPASNLSACQYAVDRPV 324
>gi|24234708 paired-like homeodomain transcription factor 2 isoform
b [Homo sapiens]
Length = 317
Score = 527 bits (1357), Expect = e-150
Identities = 258/260 (99%), Positives = 258/260 (99%)
Query: 65 PEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREE 124
P A EKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREE
Sbjct: 58 PGANEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREE 117
Query: 125 IAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYN 184
IAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYN
Sbjct: 118 IAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYN 177
Query: 185 NWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGS 244
NWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGS
Sbjct: 178 NWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGS 237
Query: 245 SLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYA 304
SLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYA
Sbjct: 238 SLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYA 297
Query: 305 SVQNPASNLSACQYAVDRPV 324
SVQNPASNLSACQYAVDRPV
Sbjct: 298 SVQNPASNLSACQYAVDRPV 317
>gi|24234711 paired-like homeodomain transcription factor 2 isoform
a [Homo sapiens]
Length = 271
Score = 524 bits (1350), Expect = e-149
Identities = 256/256 (100%), Positives = 256/256 (100%)
Query: 69 EKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVW 128
EKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVW
Sbjct: 16 EKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVW 75
Query: 129 TNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAA 188
TNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAA
Sbjct: 76 TNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAA 135
Query: 189 KGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNS 248
KGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNS
Sbjct: 136 KGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNS 195
Query: 249 LNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQN 308
LNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQN
Sbjct: 196 LNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQN 255
Query: 309 PASNLSACQYAVDRPV 324
PASNLSACQYAVDRPV
Sbjct: 256 PASNLSACQYAVDRPV 271
>gi|152963644 paired-like homeodomain transcription factor 1 [Homo
sapiens]
Length = 314
Score = 364 bits (935), Expect = e-101
Identities = 203/330 (61%), Positives = 234/330 (70%), Gaps = 30/330 (9%)
Query: 1 MNCMKGPLHLEHRAAGTKLSAVSSSSCHHPQPLAMASVLA-PGQPRSLDSSKHRLEVHTI 59
M+ KG + LE G + P + A LA P PR LE ++
Sbjct: 1 MDAFKGGMSLERLPEGLRPPPPP------PHDMGPAFHLARPADPRE------PLE-NSA 47
Query: 60 SDTSSPEAAEKDKSQQGKNEDV---------GAEDPSKKKRQRRQRTHFTSQQLQELEAT 110
S++S E EK++ + K + GA+DP+KKK+QRRQRTHFTSQQLQELEAT
Sbjct: 48 SESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEAT 107
Query: 111 FQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGL 170
FQRNRYPDMS REEIAVWTNLTE RVRVWFKNRRAKWRKRERNQQ +LCK G+ PQF+GL
Sbjct: 108 FQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGL 167
Query: 171 MQPYDDMY-PGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSM 229
+QPY+D+Y GYSYNNWAAK L A LSTKSF FFNSM +PLSSQSMFS P+SISSM+M
Sbjct: 168 VQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSM--SPLSSQSMFSAPSSISSMTM 225
Query: 230 SSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPY-VYRDTCNSSL 288
SSM P AV G+P S LNN+NNL+ SLNSA+ ACPY P PY VYRDTCNSSL
Sbjct: 226 PSSMGPGAVPGMPNS---GLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSL 282
Query: 289 ASLRLKAKQHSSFGYASVQNPASNLSACQY 318
ASLRLK+KQHSSFGY +Q PAS L+ACQY
Sbjct: 283 ASLRLKSKQHSSFGYGGLQGPASGLNACQY 312
>gi|4826912 paired-like homeodomain 3 [Homo sapiens]
Length = 302
Score = 297 bits (761), Expect = 7e-81
Identities = 160/253 (63%), Positives = 187/253 (73%), Gaps = 16/253 (6%)
Query: 84 EDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNR 143
ED S KK+QRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNR
Sbjct: 54 EDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNR 113
Query: 144 RAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPF 203
RAKWRKRER+QQAELCK F GL+ PY+++YPGYSY NW K L + L+ K+FPF
Sbjct: 114 RAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKAL-APPLAAKTFPF 172
Query: 204 -FNSMNVNPLSSQSMFSPPNSI-SSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLN 261
FNS+NV PL+SQ +FSPP+SI +SM S++ P V G PG+ L+ +++
Sbjct: 173 AFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPG-PGALQGLGGGPPGLAPAAVS 231
Query: 262 SAVPTPACPY--------APPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQN--PAS 311
S +CPY A + PYVYRD CNSSLASLRLKAKQH+SF Y +V PA+
Sbjct: 232 SG--AVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLRLKAKQHASFSYPAVHGPPPAA 289
Query: 312 NLSACQYAVDRPV 324
NLS CQYAV+RPV
Sbjct: 290 NLSPCQYAVERPV 302
>gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens]
Length = 326
Score = 119 bits (298), Expect = 4e-27
Identities = 83/233 (35%), Positives = 122/233 (52%), Gaps = 22/233 (9%)
Query: 70 KDKSQQGKNEDVGAEDPSK--KKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAV 127
K ++G+ +++G + S ++RR RT FTS QL+ELE FQ+ YPD+ RE++A+
Sbjct: 108 KGMQEKGELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLAL 167
Query: 128 WTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWA 187
T LTEARV+VWF+NRRAKWRKRER Q + K+ F ++ + P D YP N WA
Sbjct: 168 RTELTEARVQVWFQNRRAKWRKRERYGQIQQAKSHFAATYDISVLPRTDSYPQIQNNLWA 227
Query: 188 AKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLN 247
+ +++ P S + P S SP S S+ + + VP
Sbjct: 228 GNASGGSVVTSCMLPRDTSSCMTPYS----HSPRTDSSYTGFSNHQ--NQFSHVP----- 276
Query: 248 SLNNLNNLSSPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSS 300
LNN + SL + +A T P R +SS+A LR+KAK+H++
Sbjct: 277 ----LNNFFTDSLLTGATN---GHAFETKPEFERR--SSSIAVLRMKAKEHTA 320
>gi|55743092 aristaless-like homeobox 4 [Homo sapiens]
Length = 411
Score = 112 bits (279), Expect = 6e-25
Identities = 81/223 (36%), Positives = 114/223 (51%), Gaps = 27/223 (12%)
Query: 83 AEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKN 142
A+ S K ++RR RT FTS QL+ELE FQ+ YPD+ RE++A+ T+LTEARV+VWF+N
Sbjct: 205 ADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQN 264
Query: 143 RRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMY-----PGYSYNNWAAKGLTSASLS 197
RRAKWRKRER Q + + F + + + Y P + NN AA + + +
Sbjct: 265 RRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWLGNNGAASPVPACVVP 324
Query: 198 TKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSS 257
P S + + PP S +S V A + V + + SL +L S
Sbjct: 325 CDPVPACMSPHAH---------PPGSGASSVTDFLSVSGAGSHVGQTHMGSLFGAASL-S 374
Query: 258 PSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSS 300
P LN Y P D SS+A+LR+KAK+HS+
Sbjct: 375 PGLNG--------YELNGEP----DRKTSSIAALRMKAKEHSA 405
>gi|24497589 aristaless related homeobox [Homo sapiens]
Length = 562
Score = 108 bits (269), Expect = 8e-24
Identities = 88/253 (34%), Positives = 132/253 (52%), Gaps = 24/253 (9%)
Query: 65 PEAAEKDKSQQGKNEDVGA--EDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTR 122
PE AE + G+ E+ K++QRR RT FTS QL+ELE FQ+ YPD+ TR
Sbjct: 299 PEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTR 358
Query: 123 EEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGF---GP-QFNGLMQPYDDMY 178
EE+A+ +LTEARV+VWF+NRRAKWRKRE+ A+ G GP + PY D
Sbjct: 359 EELAMRLDLTEARVQVWFQNRRAKWRKREK-AGAQTHPPGLPFPGPLSATHPLSPYLDAS 417
Query: 179 PGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSM----- 233
P ++ T+A+ + + F S+ P S+ S P S + + +S+ +
Sbjct: 418 PFPPHHPALDSAWTAAAAAAAA--AFPSLPPPPGSA----SLPPSGAPLGLSTFLGAAVF 471
Query: 234 -VPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPT-----PPYVYRDTCNSS 287
P+ ++ G +++ L + S+ + PTPA A + P D SS
Sbjct: 472 RHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASS 531
Query: 288 LASLRLKAKQHSS 300
+A+LRLKAK+H++
Sbjct: 532 IAALRLKAKEHAA 544
>gi|122937484 dorsal root ganglia homeobox [Homo sapiens]
Length = 268
Score = 105 bits (261), Expect = 7e-23
Identities = 74/232 (31%), Positives = 110/232 (47%), Gaps = 39/232 (16%)
Query: 76 GKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEAR 135
G + +D +++QRR RT FT QQL+ LEA F + YPD+ TREE+A+ NLTEAR
Sbjct: 22 GNHSSGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEAR 81
Query: 136 VRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSAS 195
V+VWF+NRRAKWRK ER G Q G +P ++ P
Sbjct: 82 VQVWFQNRRAKWRKTER---------GASDQEPGAKEPMAEVTP---------------- 116
Query: 196 LSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSA---VTGVPGSSLNSLNNL 252
P ++N P Q+ + S+ ++ P+ + +PG+ LN+
Sbjct: 117 ------PPVRNINSPPPGDQARSKKEALEAQQSLGRTVGPAGPFFPSCLPGTLLNTATYA 170
Query: 253 NNLSSPSLNSAVPTPACPYAPP-----TPPYVYRDTCNSSLASLRLKAKQHS 299
LS + P +C P P Y + +S+A+LR+KA++HS
Sbjct: 171 QALSHVASLKGGPLCSCCVPDPMGLSFLPTYGCQSNRTASVATLRMKAREHS 222
>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
Length = 505
Score = 104 bits (259), Expect = 1e-22
Identities = 89/281 (31%), Positives = 128/281 (45%), Gaps = 46/281 (16%)
Query: 77 KNEDVGAE-DPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEAR 135
+ DV +E D K++QRR RT FT++QL+ELE F+R YPD+ TREE+A T LTEAR
Sbjct: 201 EGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEAR 260
Query: 136 VRVWFKNRRAKWRKRE-RNQQA---ELCKNGFGPQFNGLMQPY---DDMYPGYSYNN--- 185
V+VWF NRRA+WRK+ NQ A L GF P + PY D YP + +
Sbjct: 261 VQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGG 320
Query: 186 ----------------------WAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSP-PN 222
AA +SA + SF ++ +NP + + +P N
Sbjct: 321 STVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSN 380
Query: 223 SISSMSMSSSMVPSAVTGVPGS---------SLNSLNNLNNLSSPSLNSAVPTPACPYAP 273
+S MS PSAV P + L+S +++ S +S P + P +
Sbjct: 381 GLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSISASCSQRADSIKPGDSLPTSQ 440
Query: 274 PTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLS 314
P Y T + + Q+ +G +V A N+S
Sbjct: 441 AYCPPTYSTT---GYSVDPVAGYQYGQYGQTAVDYLAKNVS 478
>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
Length = 520
Score = 103 bits (258), Expect = 2e-22
Identities = 84/246 (34%), Positives = 116/246 (47%), Gaps = 47/246 (19%)
Query: 77 KNEDVGAE-DPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEAR 135
+ DV +E D K++QRR RT FT++QL+ELE F+R YPD+ TREE+A T LTEAR
Sbjct: 201 EGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEAR 260
Query: 136 VRVWFKNRRAKWRKRE-RNQQA---ELCKNGFGPQFNGLMQPY---DDMYPGYSYNN--- 185
V+VWF NRRA+WRK+ NQ A L GF P + PY D YP + +
Sbjct: 261 VQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGG 320
Query: 186 ----------------------WAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSP-PN 222
AA +SA + SF ++ +NP + + +P N
Sbjct: 321 STVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSN 380
Query: 223 SISSMSMSSSMVPSAVTGVPGS---------SLNSLNNLNNLSSPSLNSAVPTPACP--- 270
+S MS PSAV P + L+S +++ S +S P + P
Sbjct: 381 GLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSISASCSQRADSIKPGDSLPTSQ 440
Query: 271 -YAPPT 275
Y PPT
Sbjct: 441 AYCPPT 446
>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
Length = 518
Score = 103 bits (258), Expect = 2e-22
Identities = 84/246 (34%), Positives = 116/246 (47%), Gaps = 47/246 (19%)
Query: 77 KNEDVGAE-DPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEAR 135
+ DV +E D K++QRR RT FT++QL+ELE F+R YPD+ TREE+A T LTEAR
Sbjct: 199 EGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEAR 258
Query: 136 VRVWFKNRRAKWRKRE-RNQQA---ELCKNGFGPQFNGLMQPY---DDMYPGYSYNN--- 185
V+VWF NRRA+WRK+ NQ A L GF P + PY D YP + +
Sbjct: 259 VQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGG 318
Query: 186 ----------------------WAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSP-PN 222
AA +SA + SF ++ +NP + + +P N
Sbjct: 319 STVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSYSDSFMNPAAPSNHMNPVSN 378
Query: 223 SISSMSMSSSMVPSAVTGVPGS---------SLNSLNNLNNLSSPSLNSAVPTPACP--- 270
+S MS PSAV P + L+S +++ S +S P + P
Sbjct: 379 GLSPQVMSILGNPSAVPPQPQADFSISPLHGGLDSATSISASCSQRADSIKPGDSLPTSQ 438
Query: 271 -YAPPT 275
Y PPT
Sbjct: 439 AYCPPT 444
>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
Length = 343
Score = 100 bits (249), Expect = 2e-21
Identities = 48/102 (47%), Positives = 70/102 (68%)
Query: 89 KKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWR 148
K ++RR RT F++ QL+ELE FQ+ YPD+ RE++A+ T+LTEARV+VWF+NRRAKWR
Sbjct: 150 KSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWR 209
Query: 149 KRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKG 190
KRER + + +N F ++ + P D +P + WA+ G
Sbjct: 210 KRERYGKIQEGRNPFTAAYDISVLPRTDSHPQLQNSLWASPG 251
>gi|126116581 retina and anterior neural fold homeobox [Homo
sapiens]
Length = 346
Score = 99.8 bits (247), Expect = 3e-21
Identities = 76/231 (32%), Positives = 106/231 (45%), Gaps = 37/231 (16%)
Query: 83 AEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKN 142
+E+ KK+ RR RT FT+ QL ELE F+++ YPD+ +REE+A NL E RV+VWF+N
Sbjct: 127 SEEEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQN 186
Query: 143 RRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSF- 201
RRAKWR++E+ + + + K P + P + G +L +S+
Sbjct: 187 RRAKWRRQEKLEVSSM-KLQDSPLLSFSRSPPSATLSPLGAGPGSGGGPAGGALPLESWL 245
Query: 202 -PFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSL 260
P L S F PP + +P++ T P P L
Sbjct: 246 GPPLPGGGATALQSLPGFGPP---------AQSLPASYTPPPP------------PPPFL 284
Query: 261 NSAVPTPAC-PYAPPTPPYV------------YRDTCNSSLASLRLKAKQH 298
NS P P APP P Y D NSS+A+LRLKAK+H
Sbjct: 285 NSPPLGPGLQPLAPPPPSYPCGPGFGDKFPLDEADPRNSSIAALRLKAKEH 335
>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
Length = 483
Score = 95.5 bits (236), Expect = 6e-20
Identities = 79/233 (33%), Positives = 104/233 (44%), Gaps = 24/233 (10%)
Query: 57 HTISDTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRY 116
H+I S E A +S +G + D + P K+K QRR RT FT++QL+ELE F+R Y
Sbjct: 185 HSIDGILS-ERASAPQSDEGSDIDSEPDLPLKRK-QRRSRTTFTAEQLEELERAFERTHY 242
Query: 117 PDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQA----ELCKNGFGPQFNGLMQ 172
PD+ TREE+A LTEARV+VWF NRRA+WRK+ Q L GF P +
Sbjct: 243 PDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLP 302
Query: 173 PYDDMYPGYSYNNWAAKGLTSASLSTKSFP--------FFNSMNVNPLSSQSMFSPPNSI 224
Y SY + S ST P +++ NP SS + P
Sbjct: 303 TY--QLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRH 360
Query: 225 SSMSMSSSMVPSAVTGVPGSSLNSLNNL--NNLSSPSLNSAVPTPACPYAPPT 275
S + S VP P N +N N LS + P+ P T
Sbjct: 361 GFSSYTDSFVP------PSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQT 407
>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
Length = 505
Score = 95.5 bits (236), Expect = 6e-20
Identities = 79/233 (33%), Positives = 104/233 (44%), Gaps = 24/233 (10%)
Query: 57 HTISDTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRY 116
H+I S E A +S +G + D + P K+K QRR RT FT++QL+ELE F+R Y
Sbjct: 186 HSIDGILS-ERASAPQSDEGSDIDSEPDLPLKRK-QRRSRTTFTAEQLEELERAFERTHY 243
Query: 117 PDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQA----ELCKNGFGPQFNGLMQ 172
PD+ TREE+A LTEARV+VWF NRRA+WRK+ Q L GF P +
Sbjct: 244 PDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLP 303
Query: 173 PYDDMYPGYSYNNWAAKGLTSASLSTKSFP--------FFNSMNVNPLSSQSMFSPPNSI 224
Y SY + S ST P +++ NP SS + P
Sbjct: 304 TY--QLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRH 361
Query: 225 SSMSMSSSMVPSAVTGVPGSSLNSLNNL--NNLSSPSLNSAVPTPACPYAPPT 275
S + S VP P N +N N LS + P+ P T
Sbjct: 362 GFSSYTDSFVP------PSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQT 408
>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
Length = 484
Score = 95.5 bits (236), Expect = 6e-20
Identities = 79/233 (33%), Positives = 104/233 (44%), Gaps = 24/233 (10%)
Query: 57 HTISDTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRY 116
H+I S E A +S +G + D + P K+K QRR RT FT++QL+ELE F+R Y
Sbjct: 186 HSIDGILS-ERASAPQSDEGSDIDSEPDLPLKRK-QRRSRTTFTAEQLEELERAFERTHY 243
Query: 117 PDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQA----ELCKNGFGPQFNGLMQ 172
PD+ TREE+A LTEARV+VWF NRRA+WRK+ Q L GF P +
Sbjct: 244 PDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLP 303
Query: 173 PYDDMYPGYSYNNWAAKGLTSASLSTKSFP--------FFNSMNVNPLSSQSMFSPPNSI 224
Y SY + S ST P +++ NP SS + P
Sbjct: 304 TY--QLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRH 361
Query: 225 SSMSMSSSMVPSAVTGVPGSSLNSLNNL--NNLSSPSLNSAVPTPACPYAPPT 275
S + S VP P N +N N LS + P+ P T
Sbjct: 362 GFSSYTDSFVP------PSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQT 408
>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
Length = 479
Score = 95.5 bits (236), Expect = 6e-20
Identities = 79/233 (33%), Positives = 104/233 (44%), Gaps = 24/233 (10%)
Query: 57 HTISDTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRY 116
H+I S E A +S +G + D + P K+K QRR RT FT++QL+ELE F+R Y
Sbjct: 186 HSIDGILS-ERASAPQSDEGSDIDSEPDLPLKRK-QRRSRTTFTAEQLEELERAFERTHY 243
Query: 117 PDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQA----ELCKNGFGPQFNGLMQ 172
PD+ TREE+A LTEARV+VWF NRRA+WRK+ Q L GF P +
Sbjct: 244 PDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLP 303
Query: 173 PYDDMYPGYSYNNWAAKGLTSASLSTKSFP--------FFNSMNVNPLSSQSMFSPPNSI 224
Y SY + S ST P +++ NP SS + P
Sbjct: 304 TY--QLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRH 361
Query: 225 SSMSMSSSMVPSAVTGVPGSSLNSLNNL--NNLSSPSLNSAVPTPACPYAPPT 275
S + S VP P N +N N LS + P+ P T
Sbjct: 362 GFSSYTDSFVP------PSGPSNPMNPTIGNGLSPQVMGLLTNHGGVPHQPQT 408
>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
Length = 403
Score = 94.4 bits (233), Expect = 1e-19
Identities = 76/217 (35%), Positives = 101/217 (46%), Gaps = 23/217 (10%)
Query: 57 HTISDTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRY 116
H+I S E A +S +G + D + P K+K QRR RT FT++QL+ELE F+R Y
Sbjct: 186 HSIDGILS-ERASAPQSDEGSDIDSEPDLPLKRK-QRRSRTTFTAEQLEELERAFERTHY 243
Query: 117 PDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQA----ELCKNGFGPQFNGLMQ 172
PD+ TREE+A LTEARV+VWF NRRA+WRK+ Q L GF P +
Sbjct: 244 PDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLP 303
Query: 173 PYDDMYPGYSYNNWAAKGLTSASLSTKSFP--------FFNSMNVNPLSSQSMFSPPNSI 224
Y SY + S ST P +++ NP SS + P
Sbjct: 304 TY--QLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRH 361
Query: 225 SSMSMSSSMVPSAVTGVPGSSLNSLN-NLNNLSSPSL 260
S + S VP P N +N + N SP +
Sbjct: 362 GFSSYTDSFVP------PSGPSNPMNPTIGNGLSPQV 392
>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
Length = 407
Score = 94.4 bits (233), Expect = 1e-19
Identities = 76/217 (35%), Positives = 101/217 (46%), Gaps = 23/217 (10%)
Query: 57 HTISDTSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRY 116
H+I S E A +S +G + D + P K+K QRR RT FT++QL+ELE F+R Y
Sbjct: 186 HSIDGILS-ERASAPQSDEGSDIDSEPDLPLKRK-QRRSRTTFTAEQLEELERAFERTHY 243
Query: 117 PDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQA----ELCKNGFGPQFNGLMQ 172
PD+ TREE+A LTEARV+VWF NRRA+WRK+ Q L GF P +
Sbjct: 244 PDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLP 303
Query: 173 PYDDMYPGYSYNNWAAKGLTSASLSTKSFP--------FFNSMNVNPLSSQSMFSPPNSI 224
Y SY + S ST P +++ NP SS + P
Sbjct: 304 TY--QLSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRH 361
Query: 225 SSMSMSSSMVPSAVTGVPGSSLNSLN-NLNNLSSPSL 260
S + S VP P N +N + N SP +
Sbjct: 362 GFSSYTDSFVP------PSGPSNPMNPTIGNGLSPQV 392
>gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]
Length = 325
Score = 92.8 bits (229), Expect = 4e-19
Identities = 101/326 (30%), Positives = 141/326 (43%), Gaps = 63/326 (19%)
Query: 10 LEHR-AAGTKLSAVSSSSCHHPQPLAMAS------VLAPGQP-RSLDSSKHRLEVHTISD 61
L HR A +L S HP LA S L PG+ ++ S+ L V
Sbjct: 21 LGHREAVKCRLGVGGSDPGGHPGDLAPNSDPVEGATLLPGEDITTVGSTPASLAV----- 75
Query: 62 TSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMST 121
S + +K QG A +++Q+R RT FT QL ELE +F + YPD+
Sbjct: 76 --SAKDPDKQPGPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFM 133
Query: 122 REEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNGFGPQF----NGLMQ 172
REE+A+ LTE+RV+VWF+NRRAKW+KR++ L PQF
Sbjct: 134 REELALRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAA 193
Query: 173 PYDDMYPGYSYNN--WAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFS-------PPNS 223
D + N+ WAA + S P ++ +QS+ PPN
Sbjct: 194 AMGDSLCSFHANDTRWAAAAMPGVS----QLPLPPALGRQQAMAQSLSQCSLAAGPPPN- 248
Query: 224 ISSMSMSSSMVPSAVTGV---------PGSSLNSLNNLNNLS-SPSLNSAVPTPACPYAP 273
SM +S+S+ S G+ PG SL +N+S SP L S+
Sbjct: 249 --SMGLSNSLAGSNGAGLQSHLYQPAFPGMVPASLPGPSNVSGSPQLCSS---------- 296
Query: 274 PTPPYVYRDTCNSSLASLRLKAKQHS 299
P V+R T S+ASLR KA +H+
Sbjct: 297 PDSSDVWRGT---SIASLRRKALEHT 319
>gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Homo
sapiens]
Length = 382
Score = 92.8 bits (229), Expect = 4e-19
Identities = 43/71 (60%), Positives = 57/71 (80%)
Query: 87 SKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAK 146
S+ ++QRR RT FT+QQL+ LE TFQ+ YPD+ RE +A+ TNL EARV+VWFKNRRAK
Sbjct: 66 SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAK 125
Query: 147 WRKRERNQQAE 157
+RK++R+ Q E
Sbjct: 126 FRKKQRSLQKE 136
Score = 32.0 bits (71), Expect = 0.77
Identities = 17/49 (34%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Query: 43 QPRSLDSSKHRLEVH-TISDTSSPEAAEKDKSQQGKNEDVGAEDPSKKK 90
QP L S E+H ++S+ S+ E+A +D+ + ++ GAEDP +K
Sbjct: 166 QPPRLPGSDPPAELHLSLSEQSASESAPEDQPDREEDPRAGAEDPKAEK 214
>gi|14149760 orthopedia homeobox [Homo sapiens]
Length = 325
Score = 92.8 bits (229), Expect = 4e-19
Identities = 101/326 (30%), Positives = 141/326 (43%), Gaps = 63/326 (19%)
Query: 10 LEHR-AAGTKLSAVSSSSCHHPQPLAMAS------VLAPGQP-RSLDSSKHRLEVHTISD 61
L HR A +L S HP LA S L PG+ ++ S+ L V
Sbjct: 21 LGHREAVKCRLGVGGSDPGGHPGDLAPNSDPVEGATLLPGEDITTVGSTPASLAV----- 75
Query: 62 TSSPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMST 121
S + +K QG A +++Q+R RT FT QL ELE +F + YPD+
Sbjct: 76 --SAKDPDKQPGPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFM 133
Query: 122 REEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQ-----AELCKNGFGPQF----NGLMQ 172
REE+A+ LTE+RV+VWF+NRRAKW+KR++ L PQF
Sbjct: 134 REELALRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAA 193
Query: 173 PYDDMYPGYSYNN--WAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFS-------PPNS 223
D + N+ WAA + S P ++ +QS+ PPN
Sbjct: 194 AMGDSLCSFHANDTRWAAAAMPGVS----QLPLPPALGRQQAMAQSLSQCSLAAGPPPN- 248
Query: 224 ISSMSMSSSMVPSAVTGV---------PGSSLNSLNNLNNLS-SPSLNSAVPTPACPYAP 273
SM +S+S+ S G+ PG SL +N+S SP L S+
Sbjct: 249 --SMGLSNSLAGSNGAGLQSHLYQPAFPGMVPASLPGPSNVSGSPQLCSS---------- 296
Query: 274 PTPPYVYRDTCNSSLASLRLKAKQHS 299
P V+R T S+ASLR KA +H+
Sbjct: 297 PDSSDVWRGT---SIASLRRKALEHT 319
>gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Homo
sapiens]
Length = 377
Score = 92.8 bits (229), Expect = 4e-19
Identities = 43/71 (60%), Positives = 57/71 (80%)
Query: 87 SKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAK 146
S+ ++QRR RT FT+QQL+ LE TFQ+ YPD+ RE +A+ TNL EARV+VWFKNRRAK
Sbjct: 61 SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAK 120
Query: 147 WRKRERNQQAE 157
+RK++R+ Q E
Sbjct: 121 FRKKQRSLQKE 131
Score = 32.0 bits (71), Expect = 0.77
Identities = 17/49 (34%), Positives = 29/49 (59%), Gaps = 1/49 (2%)
Query: 43 QPRSLDSSKHRLEVH-TISDTSSPEAAEKDKSQQGKNEDVGAEDPSKKK 90
QP L S E+H ++S+ S+ E+A +D+ + ++ GAEDP +K
Sbjct: 161 QPPRLPGSDPPAELHLSLSEQSASESAPEDQPDREEDPRAGAEDPKAEK 209
>gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens]
Length = 217
Score = 92.0 bits (227), Expect = 6e-19
Identities = 50/105 (47%), Positives = 66/105 (62%), Gaps = 5/105 (4%)
Query: 64 SPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTRE 123
SP + Q N+ + +E+ KK++QRR RT F S QLQ LE F+R YPD RE
Sbjct: 67 SPGLTSGSDTPQQDNDQLNSEE-KKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVRE 125
Query: 124 EIAVWTNLTEARVRVWFKNRRAKWRKRER----NQQAELCKNGFG 164
++A NLTEARV+VWF+NRRAK+R+ ER N+ A L K+ G
Sbjct: 126 DLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSG 170
>gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo
sapiens]
Length = 245
Score = 92.0 bits (227), Expect = 6e-19
Identities = 50/105 (47%), Positives = 66/105 (62%), Gaps = 5/105 (4%)
Query: 64 SPEAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTRE 123
SP + Q N+ + +E+ KK++QRR RT F S QLQ LE F+R YPD RE
Sbjct: 67 SPGLTSGSDTPQQDNDQLNSEE-KKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVRE 125
Query: 124 EIAVWTNLTEARVRVWFKNRRAKWRKRER----NQQAELCKNGFG 164
++A NLTEARV+VWF+NRRAK+R+ ER N+ A L K+ G
Sbjct: 126 DLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSG 170
>gi|34365783 visual system homeobox 2 [Homo sapiens]
Length = 361
Score = 89.7 bits (221), Expect = 3e-18
Identities = 54/136 (39%), Positives = 76/136 (55%), Gaps = 19/136 (13%)
Query: 17 TKLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSSKHRLEVHTISDTSSPEAAEKDKSQQG 76
T L +S H QPL AS LD+S+ SD+ ++++ S+
Sbjct: 92 TFLEVLSDPQSVHLQPLGRAS-------GPLDTSQT-----ASSDSEDVSSSDRKMSKSA 139
Query: 77 KNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARV 136
N+ +KK+++RR RT FTS QL+ELE F YPD+ RE +A+ T L E R+
Sbjct: 140 LNQ-------TKKRKKRRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRI 192
Query: 137 RVWFKNRRAKWRKRER 152
+VWF+NRRAKWRKRE+
Sbjct: 193 QVWFQNRRAKWRKREK 208
>gi|11056038 visual system homeobox 1 isoform a [Homo sapiens]
Length = 365
Score = 89.4 bits (220), Expect = 4e-18
Identities = 51/123 (41%), Positives = 70/123 (56%), Gaps = 12/123 (9%)
Query: 30 PQPLAMASVLAPGQPRSLDSSKHRLEVHTISDTSSPEAAEKDKSQQGKNEDVGAEDPSKK 89
P+P A+ LAP +P + R + + SD + SQ D+ A K
Sbjct: 114 PEP---AAPLAPSRPPPALGRQKRSDSVSTSD---------EDSQSEDRNDLKASPTLGK 161
Query: 90 KRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRK 149
+++RR RT FT+ QL+ELE F YPD+ RE +AV T L E R++VWF+NRRAKWRK
Sbjct: 162 RKKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRK 221
Query: 150 RER 152
RE+
Sbjct: 222 REK 224
>gi|12707580 paired-like homeobox 2b [Homo sapiens]
Length = 314
Score = 88.2 bits (217), Expect = 9e-18
Identities = 67/167 (40%), Positives = 85/167 (50%), Gaps = 18/167 (10%)
Query: 2 NCMKGPLHLEHRAAGTKLSAVSSSSCHHPQPLAMASVLAPGQPRSLDSSKHRLEVHTISD 61
+CM G +A S+ S +S P+ G P S + T+ D
Sbjct: 16 SCMAGMDTSSLASAYADFSSCSQASGFQYNPIRTTFGATSGCPSLTPGS---CSLGTLRD 72
Query: 62 -TSSPEAAEKDK---SQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYP 117
SSP AA K G NE K++QRR RT FTS QL+ELE F YP
Sbjct: 73 HQSSPYAAVPYKLFTDHGGLNE---------KRKQRRIRTTFTSAQLKELERVFAETHYP 123
Query: 118 DMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER--NQQAELCKNG 162
D+ TREE+A+ +LTEARV+VWF+NRRAK+RK+ER A KNG
Sbjct: 124 DIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAAAAAAAAAKNG 170
>gi|20070107 orthodenticle homeobox 1 [Homo sapiens]
Length = 354
Score = 87.4 bits (215), Expect = 2e-17
Identities = 60/189 (31%), Positives = 105/189 (55%), Gaps = 24/189 (12%)
Query: 86 PSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRA 145
P+ ++QRR+RT FT QL LEA F + RYPD+ REE+A+ NL E+RV+VWFKNRRA
Sbjct: 32 PATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRA 91
Query: 146 KWRKRERN----------QQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSAS 195
K R+++++ +++ + G + +G P P S ++ ++ S+S
Sbjct: 92 KCRQQQQSGSGTKSRPAKKKSSPVRESSGSESSGQFTP-----PAVS-SSASSSSSASSS 145
Query: 196 LSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNL 255
+ + + NP+++ S S+S+ + SS P++++ PGS+ S++ L
Sbjct: 146 SANPAAAAAAGLGGNPVAAAS------SLSTPAASSIWSPASIS--PGSAPASVSVPEPL 197
Query: 256 SSPSLNSAV 264
++PS S +
Sbjct: 198 AAPSNTSCM 206
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.123 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,725,987
Number of Sequences: 37866
Number of extensions: 640095
Number of successful extensions: 4483
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 326
Number of HSP's successfully gapped in prelim test: 147
Number of HSP's that attempted gapping in prelim test: 3791
Number of HSP's gapped (non-prelim): 773
length of query: 324
length of database: 18,247,518
effective HSP length: 102
effective length of query: 222
effective length of database: 14,385,186
effective search space: 3193511292
effective search space used: 3193511292
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.