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Search of human proteins with 21361159
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361159 Wilms' tumour 1-associating protein isoform 1 [Homo
sapiens]
(396 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361159 Wilms' tumour 1-associating protein isoform 1 [Homo ... 773 0.0
gi|23199976 Wilms' tumour 1-associating protein isoform 2 [Homo ... 296 2e-80
gi|23199974 Wilms' tumour 1-associating protein isoform 2 [Homo ... 296 2e-80
gi|221219020 NYD-SP11 protein [Homo sapiens] 53 4e-07
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 53 5e-07
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 52 7e-07
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 52 7e-07
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 52 7e-07
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 52 7e-07
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 52 7e-07
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 52 7e-07
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 52 7e-07
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 52 7e-07
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 51 2e-06
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 51 2e-06
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 51 2e-06
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 51 2e-06
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 51 2e-06
gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens] 50 3e-06
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 50 5e-06
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 50 5e-06
gi|10864047 epidermal growth factor receptor pathway substrate 1... 49 6e-06
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens] 49 6e-06
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 49 6e-06
gi|55770834 centromere protein F [Homo sapiens] 49 8e-06
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 49 1e-05
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 49 1e-05
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 49 1e-05
gi|221139761 zinc finger protein 853 [Homo sapiens] 48 1e-05
gi|32698688 citron [Homo sapiens] 48 1e-05
>gi|21361159 Wilms' tumour 1-associating protein isoform 1 [Homo
sapiens]
Length = 396
Score = 773 bits (1995), Expect = 0.0
Identities = 396/396 (100%), Positives = 396/396 (100%)
Query: 1 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE 60
MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE
Sbjct: 1 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE 60
Query: 61 KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF 120
KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF
Sbjct: 61 KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF 120
Query: 121 FLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRI 180
FLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRI
Sbjct: 121 FLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRI 180
Query: 181 AQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQ 240
AQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQ
Sbjct: 181 AQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQ 240
Query: 241 QQQSQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTE 300
QQQSQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTE
Sbjct: 241 QQQSQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTE 300
Query: 301 DDFPSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSNDTDSSH 360
DDFPSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSNDTDSSH
Sbjct: 301 DDFPSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSNDTDSSH 360
Query: 361 DPQEEKAVSGKGNRTVGSRHVQNGLDSSVNVQGSVL 396
DPQEEKAVSGKGNRTVGSRHVQNGLDSSVNVQGSVL
Sbjct: 361 DPQEEKAVSGKGNRTVGSRHVQNGLDSSVNVQGSVL 396
>gi|23199976 Wilms' tumour 1-associating protein isoform 2 [Homo
sapiens]
Length = 151
Score = 296 bits (759), Expect = 2e-80
Identities = 150/150 (100%), Positives = 150/150 (100%)
Query: 1 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE 60
MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE
Sbjct: 1 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE 60
Query: 61 KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF 120
KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF
Sbjct: 61 KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF 120
Query: 121 FLKMKGELEQTKDKLEQAQNELSAWKFTPD 150
FLKMKGELEQTKDKLEQAQNELSAWKFTPD
Sbjct: 121 FLKMKGELEQTKDKLEQAQNELSAWKFTPD 150
>gi|23199974 Wilms' tumour 1-associating protein isoform 2 [Homo
sapiens]
Length = 151
Score = 296 bits (759), Expect = 2e-80
Identities = 150/150 (100%), Positives = 150/150 (100%)
Query: 1 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE 60
MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE
Sbjct: 1 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE 60
Query: 61 KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF 120
KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF
Sbjct: 61 KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF 120
Query: 121 FLKMKGELEQTKDKLEQAQNELSAWKFTPD 150
FLKMKGELEQTKDKLEQAQNELSAWKFTPD
Sbjct: 121 FLKMKGELEQTKDKLEQAQNELSAWKFTPD 150
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 53.1 bits (126), Expect = 4e-07
Identities = 65/285 (22%), Positives = 130/285 (45%), Gaps = 39/285 (13%)
Query: 4 EEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALE-GKYTDLNSNDVTGLRESEEKL 62
EE L ++ + K +A +E L W++ + + + + +L + L + +EK+
Sbjct: 1732 EEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKM 1791
Query: 63 KQQQQESARRENILV---MRLATKEQE----MQECTTQIQYLKQV-----QQPSVAQLRS 110
++++ R+ L+ M+LA K + M+E T L Q ++ ++AQ +
Sbjct: 1792 PEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKE 1851
Query: 111 TMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAW---------KFTPDSQT----GKKL 157
+ NL + K + L +K +L Q +N+L + K T + +T +KL
Sbjct: 1852 KLAQRKENLLYNKER--LTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKL 1909
Query: 158 MAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEG 217
+ L+Q L ++ Q ++AQ + +LAL+K + K + EL+ I +E+
Sbjct: 1910 AETEKKLVQVEDSLAKK--QEKLAQEKMKLALEKAMVQGKKRLRGELD---IAKEEKALN 1964
Query: 218 MQSTILVLQQQLKETRQQLAQYQQQQSQASAPSTSRTTASEPVEQ 262
++ ++L E + +L + ++ S+ P TSR VEQ
Sbjct: 1965 LE------MKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQ 2003
Score = 38.1 bits (87), Expect = 0.014
Identities = 53/245 (21%), Positives = 108/245 (44%), Gaps = 32/245 (13%)
Query: 4 EEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLK 63
EE L ++ R + + +A + ++ Q + + EGK+ L + EKL
Sbjct: 1599 EEKLAQEERQLAQEERKLA--QAYVKITQDDREMAQAEGKFAQKEET----LAQRGEKLS 1652
Query: 64 QQQQESARRENILVMR---LATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF 120
Q+ ++ A++ L + +A +E+++ + ++ +K + V +L P
Sbjct: 1653 QEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEEL------PQREQN 1706
Query: 121 FLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRI 180
+ EL Q ++LE ELS WK +Q KL+ + + L +E + L Q
Sbjct: 1707 LDWQEKELAQELEELEWDMEELS-WKEEELNQEEGKLVEEKKKLAEEEEALAWQR----- 1760
Query: 181 AQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQ 240
+K EE K +Q+E + +IQ E++ + + +++L R+QL + +
Sbjct: 1761 ---------EKLSEEETKLAQEE--ELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKK 1809
Query: 241 QQQSQ 245
+ +Q
Sbjct: 1810 MKLAQ 1814
Score = 28.9 bits (63), Expect = 8.5
Identities = 34/199 (17%), Positives = 88/199 (44%), Gaps = 5/199 (2%)
Query: 49 SNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQL 108
+N + + EEK+ +++ + AR+ + ++ L +E+ E I +LK+ +
Sbjct: 2147 ANKMRRMINKEEKMTEEESKLARKHSEVI--LDDEEEGGIEEEEVIPFLKRRWRKRKEAK 2204
Query: 109 RSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRML--IQ 166
R + +++ E E +++E +EL + + ++ + R ++
Sbjct: 2205 RGDKPKEKFSSQVDEVESE-EHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVR 2263
Query: 167 ENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQ 226
E +E ++ +G Q+E E +KK +E K + + + + + EE+ + T +
Sbjct: 2264 EEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSD 2323
Query: 227 QQLKETRQQLAQYQQQQSQ 245
++ +E L + ++ +
Sbjct: 2324 EEEEEESCSLEEEVDREKE 2342
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 52.8 bits (125), Expect = 5e-07
Identities = 64/279 (22%), Positives = 126/279 (45%), Gaps = 40/279 (14%)
Query: 2 TNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEK 61
T +PL + R E ++ A+DE +L+ K+ + V EG+ ++ L E
Sbjct: 839 TKVKPLLQVTRQEE---ELQAKDEELLKVKEKQTKV---EGELEEMERKHQQLLEEKNIL 892
Query: 62 LKQQQQES---ARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAIN 118
+Q Q E+ A E + RLA K+QE++E ++ + ++ L++ +
Sbjct: 893 AEQLQAETELFAEAEEMRA-RLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAH 951
Query: 119 LFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQEL--GRQLS 176
+ +LE+ D+ E A+ +L K T +++ KK+ + +L +N + ++L
Sbjct: 952 I------QDLEEQLDEEEGARQKLQLEKVTAEAKI-KKMEEEILLLEDQNSKFIKEKKLM 1004
Query: 177 QGRIAQLEAELALQKKYSEEL---------------------KSSQDELNDFIIQLDEEV 215
+ RIA+ ++LA +++ ++ L + ++ EL +LD E
Sbjct: 1005 EDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGET 1064
Query: 216 EGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPSTSRT 254
+Q I LQ Q+ E + QLA+ +++ A A T
Sbjct: 1065 TDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDET 1103
Score = 45.4 bits (106), Expect = 9e-05
Identities = 58/271 (21%), Positives = 120/271 (44%), Gaps = 29/271 (10%)
Query: 10 KVRLSETDFKVMARDELILRWKQYEAYVQALEGKYT-DLNSNDVTGLRESEEKLKQQQQ- 67
+ +L E + ++ A ++ LR E +QA++ ++ DL + D + +KQ ++
Sbjct: 1545 RTQLEELEDELQATEDAKLR---LEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVREL 1601
Query: 68 ----ESARRENILVMRLATK-EQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFL 122
E R++ L + K E ++++ QI+ + + + QLR
Sbjct: 1602 EAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLR------------- 1648
Query: 123 KMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQ 182
K++ +++ + +LE+A+ F ++ KKL + ++Q +EL R A+
Sbjct: 1649 KLQAQMKDYQRELEEARASRDEI-FAQSKESEKKLKSLEAEILQLQEELASSERARRHAE 1707
Query: 183 LEA-ELALQKKYSEELKSS----QDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLA 237
E ELA + S KS+ + L I QL+EE+E QS + +L + ++T Q+
Sbjct: 1708 QERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVD 1767
Query: 238 QYQQQQSQASAPSTSRTTASEPVEQSEATSK 268
+ + + + A + +E+ K
Sbjct: 1768 TLNAELAAERSAAQKSDNARQQLERQNKELK 1798
Score = 45.1 bits (105), Expect = 1e-04
Identities = 52/267 (19%), Positives = 116/267 (43%), Gaps = 14/267 (5%)
Query: 31 KQYEAYVQALEGKYTDLNSNDVT-GLRESEEKLKQQQQESARRENILVMRLATKEQEMQE 89
+Q + ++ + K+ L + + + R +EE+ + + AR + + LA +E E
Sbjct: 1440 RQVASNLEKKQKKFDQLLAEEKSISARYAEER--DRAEAEAREKETKALSLARALEEALE 1497
Query: 90 CTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLK-----MKGELEQTKDKLEQAQNELSA 144
+ + + + + L S+ D N+ L+ ++ ++E+ + +LE+ ++EL A
Sbjct: 1498 AKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQA 1557
Query: 145 W-----KFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKS 199
+ + Q K + E E ++L ++ +LEAEL ++K +
Sbjct: 1558 TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVA 1617
Query: 200 SQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPSTSRTTASEP 259
S+ ++ + L+ ++E + +QL++ + Q+ YQ++ +A A S A
Sbjct: 1618 SKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARA-SRDEIFAQSK 1676
Query: 260 VEQSEATSKDCSRLTNGPSNGSSSRQR 286
+ + S + L SS R R
Sbjct: 1677 ESEKKLKSLEAEILQLQEELASSERAR 1703
Score = 41.6 bits (96), Expect = 0.001
Identities = 51/232 (21%), Positives = 109/232 (46%), Gaps = 17/232 (7%)
Query: 35 AYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQI 94
A +ALE K N LR E L + + + + L EQ+++E TQ+
Sbjct: 1491 ALEEALEAKEEFERQNKQ--LRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQL 1548
Query: 95 QYLK-QVQQPSVAQLRSTMVDPAINLFF---LKMKGELEQTKDKLEQAQ-NELSAWKFTP 149
+ L+ ++Q A+LR + A+ F L+ + E + K +L Q EL A
Sbjct: 1549 EELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDE 1608
Query: 150 DSQTGKKLMAKCRMLIQENQELGRQLSQG---------RIAQLEAELALQKKYSEELKSS 200
Q + +K +M I + ++L Q+ ++ +L+A++ ++ EE ++S
Sbjct: 1609 RKQRALAVASKKKMEI-DLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARAS 1667
Query: 201 QDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPSTS 252
+DE+ + +++++ +++ IL LQ++L + + +Q++ + + T+
Sbjct: 1668 RDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITN 1719
Score = 34.3 bits (77), Expect = 0.20
Identities = 47/262 (17%), Positives = 109/262 (41%), Gaps = 10/262 (3%)
Query: 31 KQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQEC 90
++ E + L+G+ TDL + E + ++ + + + A++E L LA + E
Sbjct: 1051 QELEKAKRKLDGETTDLQDQ----IAELQAQIDELKLQLAKKEEELQGALARGDDETLHK 1106
Query: 91 TTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPD 150
++ ++++Q +A+L+ + K + + ++LE + EL T
Sbjct: 1107 NNALKVVRELQA-QIAELQEDFESEKASRN--KAEKQKRDLSEELEALKTELEDTLDTTA 1163
Query: 151 SQTGKKLMAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQ 210
+Q ++L K + E ++ + ++ AQ++ EEL ++ F
Sbjct: 1164 AQ--QELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKAN 1221
Query: 211 LDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAP-STSRTTASEPVEQSEATSKD 269
L++ +G+++ L ++K +Q A+ + ++ + A SE ++
Sbjct: 1222 LEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEK 1281
Query: 270 CSRLTNGPSNGSSSRQRTSGSG 291
S+L N N S+ + G
Sbjct: 1282 ASKLQNELDNVSTLLEEAEKKG 1303
Score = 29.6 bits (65), Expect = 5.0
Identities = 47/226 (20%), Positives = 93/226 (41%), Gaps = 45/226 (19%)
Query: 31 KQYEAYVQALEGKYTDLNSN------DVTGLRESEEKL-------KQQQQESARRENILV 77
K E V AL+ + D + L E+++KL Q+ +E A + L
Sbjct: 1360 KNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLE 1419
Query: 78 MRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTK-DKLE 136
+QE+ + T + + +QV A NL E +Q K D+L
Sbjct: 1420 KTKNRLQQELDDLTVDLDHQRQV---------------ASNL-------EKKQKKFDQLL 1457
Query: 137 QAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEE 196
+ +SA ++ + + A+ R + L R L + A+ E E + +++
Sbjct: 1458 AEEKSISA-RYAEERDRAE---AEAREKETKALSLARALEEALEAKEEFE-----RQNKQ 1508
Query: 197 LKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQ 242
L++ ++L + + V ++ + L+QQ++E R QL + + +
Sbjct: 1509 LRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDE 1554
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 52.4 bits (124), Expect = 7e-07
Identities = 52/217 (23%), Positives = 99/217 (45%), Gaps = 20/217 (9%)
Query: 45 TDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPS 104
T+L + + L ++ E +QQ A R + L +++++Q+ +Q LK + +
Sbjct: 2420 TELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ-LKSEEMQT 2478
Query: 105 VAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRML 164
V Q + A+ FL K L Q + +EQ + +L Q + +AK + L
Sbjct: 2479 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE--------QLFQDEVAKAQQL 2530
Query: 165 IQENQELGRQLSQGR---IAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQST 221
+E Q +Q+ Q R +A +E Q + E ++ Q+EL QL+++ +
Sbjct: 2531 REEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQ----QLEQQRRQQEEL 2586
Query: 222 ILVLQQQLKETRQQLAQYQQQQSQASAPSTSRTTASE 258
+ Q+L+E Q L ++Q +A+ + TAS+
Sbjct: 2587 LAEENQRLREQLQLL----EEQHRAALAHSEEVTASQ 2619
Score = 43.5 bits (101), Expect = 3e-04
Identities = 55/275 (20%), Positives = 119/275 (43%), Gaps = 26/275 (9%)
Query: 1 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE 60
M EE L ++ R E + L + + EA+ QA RE++E
Sbjct: 1344 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQA-----------KAQAEREAKE 1392
Query: 61 KLKQQQQESARRENILVMRLATK---EQEMQEC--TTQIQYLKQVQQPSVAQLRSTMVDP 115
++ Q+E RRE V K ++E+Q+ +++ + + +Q A+ ++
Sbjct: 1393 LQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEE 1452
Query: 116 AINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQL 175
I + L +LE T+ + A+ EL A + + +K A+ +E + L RQ+
Sbjct: 1453 EIRVVRL----QLEATERQRGGAEGELQALRARAEEAEAQKRQAQ-----EEAERLRRQV 1503
Query: 176 SQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQ- 234
+ +AE+ L + E ++++++ + ++ ++ + Q +++ RQ
Sbjct: 1504 QDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQV 1563
Query: 235 QLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKD 269
Q+A Q+S + + R + +E Q E + ++
Sbjct: 1564 QVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1598
Score = 38.5 bits (88), Expect = 0.011
Identities = 48/231 (20%), Positives = 95/231 (41%), Gaps = 17/231 (7%)
Query: 52 VTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTT-QIQYLKQVQQPSVAQLRS 110
V LRE E+ QQQ E+ R L + + E ++Q + QQ S+AQ +
Sbjct: 1603 VAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEA 1662
Query: 111 TMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLI----Q 166
+ EQ + E A+ EL + + ++L A+ ++
Sbjct: 1663 EKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAET 1722
Query: 167 ENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQ 226
E E RQL + +A+L+ E A + +EL++ + ++ E+E + ++ +
Sbjct: 1723 EQGEQQRQLLEEELARLQREAAAATQKRQELEAE-------LAKVRAEMEVLLASKARAE 1775
Query: 227 QQLKETRQQLAQYQQQQS-----QASAPSTSRTTASEPVEQSEATSKDCSR 272
++ + T ++ Q + ++ A + R A E Q + +D +R
Sbjct: 1776 EESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAAR 1826
Score = 36.2 bits (82), Expect = 0.053
Identities = 49/255 (19%), Positives = 104/255 (40%), Gaps = 16/255 (6%)
Query: 22 ARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR----ENILV 77
A +E + K V+ L+ K + +ES +L+ Q+ + +R E
Sbjct: 1996 AEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHA 2055
Query: 78 MRLATKEQEMQECTTQIQ-YLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLE 136
+ KEQE+Q+ Q Q L Q++ + A R+ A +++ E E + + +
Sbjct: 2056 FAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA-----AEEAEEARVQAEREAAQSRRQ 2110
Query: 137 QAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQL------EAELALQ 190
+ E +Q + A L +E ++ + +Q A L +AE+
Sbjct: 2111 VEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKH 2170
Query: 191 KKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPS 250
KK++E+ + ++ + L ++E +L ++L+ + + + +Q+SQ
Sbjct: 2171 KKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEEL 2230
Query: 251 TSRTTASEPVEQSEA 265
S E + + +A
Sbjct: 2231 FSVRVQMEELSKLKA 2245
Score = 35.4 bits (80), Expect = 0.091
Identities = 56/255 (21%), Positives = 104/255 (40%), Gaps = 46/255 (18%)
Query: 34 EAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR---ENILVMRLATKEQEMQEC 90
E +QAL + + + E+E +Q Q ES R+ E L R+ + + +E
Sbjct: 1472 EGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK 1531
Query: 91 TTQIQYLKQVQ---QPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKF 147
+Q L++++ + + +LR V+ A Q + LE AQ A
Sbjct: 1532 QRALQALEELRLQAEEAERRLRQAEVERA------------RQVQVALETAQRSAEA--- 1576
Query: 148 TPDSQTGKKLMAKCRMLIQENQELGRQLSQGR--IAQLEAELALQKKYSEELKSSQDELN 205
+L +K ++ +L R L + +AQL E + + E + +++E
Sbjct: 1577 --------ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREE-- 1626
Query: 206 DFIIQLDEEVEGMQ---STILVLQQQLKETRQQ----LAQYQQQQSQASAPSTSRTTASE 258
+ E+E Q + L L+ Q +E QQ A+ ++Q+ +A + R A E
Sbjct: 1627 -----AERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1681
Query: 259 -PVEQSEATSKDCSR 272
V Q E ++ +
Sbjct: 1682 QAVRQRELAEQELEK 1696
Score = 35.0 bits (79), Expect = 0.12
Identities = 60/285 (21%), Positives = 111/285 (38%), Gaps = 42/285 (14%)
Query: 25 ELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR-ENILVMRLATK 83
+L+ RW+ A + + L + RES + L Q++ RR E I M LA
Sbjct: 1183 QLLERWQAVLAQTDVRQRELEQLG-RQLRYYRESADPLGAWLQDARRRQEQIQAMPLADS 1241
Query: 84 EQEMQECTTQIQYLKQVQ---------QPSVAQLRSTMVDPAINLFFLKMKGE--LEQTK 132
+ ++ + L++++ Q Q + + D + L K + E K
Sbjct: 1242 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK 1301
Query: 133 DKLEQAQNELSAWKF-----------TPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIA 181
Q+ +E ++ T SQ K + R + +E + +Q ++ R
Sbjct: 1302 KPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER 1361
Query: 182 QLEAELALQKK------YSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQ 235
E E AL+K+ +++ ++ E + ++ EEV + + QQQ + +++
Sbjct: 1362 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1421
Query: 236 LAQYQQQQS--------QASAPSTSRTTASEPVE----QSEATSK 268
L Q +Q QA A SR E + Q EAT +
Sbjct: 1422 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATER 1466
Score = 34.7 bits (78), Expect = 0.15
Identities = 55/264 (20%), Positives = 105/264 (39%), Gaps = 31/264 (11%)
Query: 4 EEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLK 63
E+ L +K++ + ++ A EL+ + K+ L L+E +E++
Sbjct: 2309 EKMLKEKMQAVQEATRLKAEAELLQQQKE--------------LAQEQARRLQEDKEQMA 2354
Query: 64 QQQQESARRENILVMRLATKEQEMQECTTQIQYLK-QVQQPSVAQLRSTMVDPAINLFFL 122
QQ E + L + Q E + + + LK +V + S AQ R+ F
Sbjct: 2355 QQLAEETQG---FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR----FR 2407
Query: 123 KMKGELEQTKDKLEQAQNELSAWKFTPDSQT------GKKLMAKCRMLIQENQELGRQLS 176
K E+ + + E A E T + Q ++L L +E ++L ++
Sbjct: 2408 KQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAK 2467
Query: 177 QGRIAQLEAELALQKKYSEELKSSQDEL---NDFIIQLDEEVEGMQSTILVLQQQLKETR 233
++ E + Q++ +E ++ Q D ++Q + +E ++ + L Q
Sbjct: 2468 LLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKA 2527
Query: 234 QQLAQYQQQQSQASAPSTSRTTAS 257
QQL + QQ+Q Q R AS
Sbjct: 2528 QQLREEQQRQQQQMEQERQRLVAS 2551
Score = 29.6 bits (65), Expect = 5.0
Identities = 38/221 (17%), Positives = 90/221 (40%), Gaps = 20/221 (9%)
Query: 57 ESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPA 116
E EE+L +QQ+ R V K++++ E Q K + +L+ M +
Sbjct: 1345 EEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQ---AKAQAEREAKELQQRMQEEV 1401
Query: 117 INLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLS 176
+ + + + + Q EL + + +++ + AK R + R
Sbjct: 1402 V-----RREEAAVDAQQQKRSIQEELQQLRQSSEAE----IQAKARQAEAAERSRLRIEE 1452
Query: 177 QGRIAQLEAELALQKKYSEE-----LKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKE 231
+ R+ +L+ E +++ E L++ +E Q EE E ++ + Q+ ++
Sbjct: 1453 EIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ 1512
Query: 232 TRQQLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKDCSR 272
+LA + +++A + + A + +E+ +++ R
Sbjct: 1513 AEVELASRVKAEAEA---AREKQRALQALEELRLQAEEAER 1550
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 52.4 bits (124), Expect = 7e-07
Identities = 52/217 (23%), Positives = 99/217 (45%), Gaps = 20/217 (9%)
Query: 45 TDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPS 104
T+L + + L ++ E +QQ A R + L +++++Q+ +Q LK + +
Sbjct: 2424 TELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ-LKSEEMQT 2482
Query: 105 VAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRML 164
V Q + A+ FL K L Q + +EQ + +L Q + +AK + L
Sbjct: 2483 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE--------QLFQDEVAKAQQL 2534
Query: 165 IQENQELGRQLSQGR---IAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQST 221
+E Q +Q+ Q R +A +E Q + E ++ Q+EL QL+++ +
Sbjct: 2535 REEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQ----QLEQQRRQQEEL 2590
Query: 222 ILVLQQQLKETRQQLAQYQQQQSQASAPSTSRTTASE 258
+ Q+L+E Q L ++Q +A+ + TAS+
Sbjct: 2591 LAEENQRLREQLQLL----EEQHRAALAHSEEVTASQ 2623
Score = 43.5 bits (101), Expect = 3e-04
Identities = 55/275 (20%), Positives = 119/275 (43%), Gaps = 26/275 (9%)
Query: 1 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE 60
M EE L ++ R E + L + + EA+ QA RE++E
Sbjct: 1348 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQA-----------KAQAEREAKE 1396
Query: 61 KLKQQQQESARRENILVMRLATK---EQEMQEC--TTQIQYLKQVQQPSVAQLRSTMVDP 115
++ Q+E RRE V K ++E+Q+ +++ + + +Q A+ ++
Sbjct: 1397 LQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEE 1456
Query: 116 AINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQL 175
I + L +LE T+ + A+ EL A + + +K A+ +E + L RQ+
Sbjct: 1457 EIRVVRL----QLEATERQRGGAEGELQALRARAEEAEAQKRQAQ-----EEAERLRRQV 1507
Query: 176 SQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQ- 234
+ +AE+ L + E ++++++ + ++ ++ + Q +++ RQ
Sbjct: 1508 QDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQV 1567
Query: 235 QLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKD 269
Q+A Q+S + + R + +E Q E + ++
Sbjct: 1568 QVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1602
Score = 38.5 bits (88), Expect = 0.011
Identities = 48/231 (20%), Positives = 95/231 (41%), Gaps = 17/231 (7%)
Query: 52 VTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTT-QIQYLKQVQQPSVAQLRS 110
V LRE E+ QQQ E+ R L + + E ++Q + QQ S+AQ +
Sbjct: 1607 VAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEA 1666
Query: 111 TMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLI----Q 166
+ EQ + E A+ EL + + ++L A+ ++
Sbjct: 1667 EKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAET 1726
Query: 167 ENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQ 226
E E RQL + +A+L+ E A + +EL++ + ++ E+E + ++ +
Sbjct: 1727 EQGEQQRQLLEEELARLQREAAAATQKRQELEAE-------LAKVRAEMEVLLASKARAE 1779
Query: 227 QQLKETRQQLAQYQQQQS-----QASAPSTSRTTASEPVEQSEATSKDCSR 272
++ + T ++ Q + ++ A + R A E Q + +D +R
Sbjct: 1780 EESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAAR 1830
Score = 36.2 bits (82), Expect = 0.053
Identities = 49/255 (19%), Positives = 104/255 (40%), Gaps = 16/255 (6%)
Query: 22 ARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR----ENILV 77
A +E + K V+ L+ K + +ES +L+ Q+ + +R E
Sbjct: 2000 AEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHA 2059
Query: 78 MRLATKEQEMQECTTQIQ-YLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLE 136
+ KEQE+Q+ Q Q L Q++ + A R+ A +++ E E + + +
Sbjct: 2060 FAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA-----AEEAEEARVQAEREAAQSRRQ 2114
Query: 137 QAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQL------EAELALQ 190
+ E +Q + A L +E ++ + +Q A L +AE+
Sbjct: 2115 VEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKH 2174
Query: 191 KKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPS 250
KK++E+ + ++ + L ++E +L ++L+ + + + +Q+SQ
Sbjct: 2175 KKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEEL 2234
Query: 251 TSRTTASEPVEQSEA 265
S E + + +A
Sbjct: 2235 FSVRVQMEELSKLKA 2249
Score = 35.4 bits (80), Expect = 0.091
Identities = 56/255 (21%), Positives = 104/255 (40%), Gaps = 46/255 (18%)
Query: 34 EAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR---ENILVMRLATKEQEMQEC 90
E +QAL + + + E+E +Q Q ES R+ E L R+ + + +E
Sbjct: 1476 EGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK 1535
Query: 91 TTQIQYLKQVQ---QPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKF 147
+Q L++++ + + +LR V+ A Q + LE AQ A
Sbjct: 1536 QRALQALEELRLQAEEAERRLRQAEVERA------------RQVQVALETAQRSAEA--- 1580
Query: 148 TPDSQTGKKLMAKCRMLIQENQELGRQLSQGR--IAQLEAELALQKKYSEELKSSQDELN 205
+L +K ++ +L R L + +AQL E + + E + +++E
Sbjct: 1581 --------ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREE-- 1630
Query: 206 DFIIQLDEEVEGMQ---STILVLQQQLKETRQQ----LAQYQQQQSQASAPSTSRTTASE 258
+ E+E Q + L L+ Q +E QQ A+ ++Q+ +A + R A E
Sbjct: 1631 -----AERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1685
Query: 259 -PVEQSEATSKDCSR 272
V Q E ++ +
Sbjct: 1686 QAVRQRELAEQELEK 1700
Score = 35.0 bits (79), Expect = 0.12
Identities = 60/285 (21%), Positives = 111/285 (38%), Gaps = 42/285 (14%)
Query: 25 ELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR-ENILVMRLATK 83
+L+ RW+ A + + L + RES + L Q++ RR E I M LA
Sbjct: 1187 QLLERWQAVLAQTDVRQRELEQLG-RQLRYYRESADPLGAWLQDARRRQEQIQAMPLADS 1245
Query: 84 EQEMQECTTQIQYLKQVQ---------QPSVAQLRSTMVDPAINLFFLKMKGE--LEQTK 132
+ ++ + L++++ Q Q + + D + L K + E K
Sbjct: 1246 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK 1305
Query: 133 DKLEQAQNELSAWKF-----------TPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIA 181
Q+ +E ++ T SQ K + R + +E + +Q ++ R
Sbjct: 1306 KPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER 1365
Query: 182 QLEAELALQKK------YSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQ 235
E E AL+K+ +++ ++ E + ++ EEV + + QQQ + +++
Sbjct: 1366 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1425
Query: 236 LAQYQQQQS--------QASAPSTSRTTASEPVE----QSEATSK 268
L Q +Q QA A SR E + Q EAT +
Sbjct: 1426 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATER 1470
Score = 34.7 bits (78), Expect = 0.15
Identities = 55/264 (20%), Positives = 105/264 (39%), Gaps = 31/264 (11%)
Query: 4 EEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLK 63
E+ L +K++ + ++ A EL+ + K+ L L+E +E++
Sbjct: 2313 EKMLKEKMQAVQEATRLKAEAELLQQQKE--------------LAQEQARRLQEDKEQMA 2358
Query: 64 QQQQESARRENILVMRLATKEQEMQECTTQIQYLK-QVQQPSVAQLRSTMVDPAINLFFL 122
QQ E + L + Q E + + + LK +V + S AQ R+ F
Sbjct: 2359 QQLAEETQG---FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR----FR 2411
Query: 123 KMKGELEQTKDKLEQAQNELSAWKFTPDSQT------GKKLMAKCRMLIQENQELGRQLS 176
K E+ + + E A E T + Q ++L L +E ++L ++
Sbjct: 2412 KQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAK 2471
Query: 177 QGRIAQLEAELALQKKYSEELKSSQDEL---NDFIIQLDEEVEGMQSTILVLQQQLKETR 233
++ E + Q++ +E ++ Q D ++Q + +E ++ + L Q
Sbjct: 2472 LLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKA 2531
Query: 234 QQLAQYQQQQSQASAPSTSRTTAS 257
QQL + QQ+Q Q R AS
Sbjct: 2532 QQLREEQQRQQQQMEQERQRLVAS 2555
Score = 29.6 bits (65), Expect = 5.0
Identities = 38/221 (17%), Positives = 90/221 (40%), Gaps = 20/221 (9%)
Query: 57 ESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPA 116
E EE+L +QQ+ R V K++++ E Q K + +L+ M +
Sbjct: 1349 EEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQ---AKAQAEREAKELQQRMQEEV 1405
Query: 117 INLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLS 176
+ + + + + Q EL + + +++ + AK R + R
Sbjct: 1406 V-----RREEAAVDAQQQKRSIQEELQQLRQSSEAE----IQAKARQAEAAERSRLRIEE 1456
Query: 177 QGRIAQLEAELALQKKYSEE-----LKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKE 231
+ R+ +L+ E +++ E L++ +E Q EE E ++ + Q+ ++
Sbjct: 1457 EIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ 1516
Query: 232 TRQQLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKDCSR 272
+LA + +++A + + A + +E+ +++ R
Sbjct: 1517 AEVELASRVKAEAEA---AREKQRALQALEELRLQAEEAER 1554
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 52.4 bits (124), Expect = 7e-07
Identities = 52/217 (23%), Positives = 99/217 (45%), Gaps = 20/217 (9%)
Query: 45 TDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPS 104
T+L + + L ++ E +QQ A R + L +++++Q+ +Q LK + +
Sbjct: 2420 TELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ-LKSEEMQT 2478
Query: 105 VAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRML 164
V Q + A+ FL K L Q + +EQ + +L Q + +AK + L
Sbjct: 2479 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE--------QLFQDEVAKAQQL 2530
Query: 165 IQENQELGRQLSQGR---IAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQST 221
+E Q +Q+ Q R +A +E Q + E ++ Q+EL QL+++ +
Sbjct: 2531 REEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQ----QLEQQRRQQEEL 2586
Query: 222 ILVLQQQLKETRQQLAQYQQQQSQASAPSTSRTTASE 258
+ Q+L+E Q L ++Q +A+ + TAS+
Sbjct: 2587 LAEENQRLREQLQLL----EEQHRAALAHSEEVTASQ 2619
Score = 43.5 bits (101), Expect = 3e-04
Identities = 55/275 (20%), Positives = 119/275 (43%), Gaps = 26/275 (9%)
Query: 1 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE 60
M EE L ++ R E + L + + EA+ QA RE++E
Sbjct: 1344 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQA-----------KAQAEREAKE 1392
Query: 61 KLKQQQQESARRENILVMRLATK---EQEMQEC--TTQIQYLKQVQQPSVAQLRSTMVDP 115
++ Q+E RRE V K ++E+Q+ +++ + + +Q A+ ++
Sbjct: 1393 LQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEE 1452
Query: 116 AINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQL 175
I + L +LE T+ + A+ EL A + + +K A+ +E + L RQ+
Sbjct: 1453 EIRVVRL----QLEATERQRGGAEGELQALRARAEEAEAQKRQAQ-----EEAERLRRQV 1503
Query: 176 SQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQ- 234
+ +AE+ L + E ++++++ + ++ ++ + Q +++ RQ
Sbjct: 1504 QDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQV 1563
Query: 235 QLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKD 269
Q+A Q+S + + R + +E Q E + ++
Sbjct: 1564 QVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1598
Score = 38.5 bits (88), Expect = 0.011
Identities = 48/231 (20%), Positives = 95/231 (41%), Gaps = 17/231 (7%)
Query: 52 VTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTT-QIQYLKQVQQPSVAQLRS 110
V LRE E+ QQQ E+ R L + + E ++Q + QQ S+AQ +
Sbjct: 1603 VAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEA 1662
Query: 111 TMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLI----Q 166
+ EQ + E A+ EL + + ++L A+ ++
Sbjct: 1663 EKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAET 1722
Query: 167 ENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQ 226
E E RQL + +A+L+ E A + +EL++ + ++ E+E + ++ +
Sbjct: 1723 EQGEQQRQLLEEELARLQREAAAATQKRQELEAE-------LAKVRAEMEVLLASKARAE 1775
Query: 227 QQLKETRQQLAQYQQQQS-----QASAPSTSRTTASEPVEQSEATSKDCSR 272
++ + T ++ Q + ++ A + R A E Q + +D +R
Sbjct: 1776 EESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAAR 1826
Score = 36.2 bits (82), Expect = 0.053
Identities = 49/255 (19%), Positives = 104/255 (40%), Gaps = 16/255 (6%)
Query: 22 ARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR----ENILV 77
A +E + K V+ L+ K + +ES +L+ Q+ + +R E
Sbjct: 1996 AEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHA 2055
Query: 78 MRLATKEQEMQECTTQIQ-YLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLE 136
+ KEQE+Q+ Q Q L Q++ + A R+ A +++ E E + + +
Sbjct: 2056 FAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA-----AEEAEEARVQAEREAAQSRRQ 2110
Query: 137 QAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQL------EAELALQ 190
+ E +Q + A L +E ++ + +Q A L +AE+
Sbjct: 2111 VEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKH 2170
Query: 191 KKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPS 250
KK++E+ + ++ + L ++E +L ++L+ + + + +Q+SQ
Sbjct: 2171 KKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEEL 2230
Query: 251 TSRTTASEPVEQSEA 265
S E + + +A
Sbjct: 2231 FSVRVQMEELSKLKA 2245
Score = 35.4 bits (80), Expect = 0.091
Identities = 56/255 (21%), Positives = 104/255 (40%), Gaps = 46/255 (18%)
Query: 34 EAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR---ENILVMRLATKEQEMQEC 90
E +QAL + + + E+E +Q Q ES R+ E L R+ + + +E
Sbjct: 1472 EGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK 1531
Query: 91 TTQIQYLKQVQ---QPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKF 147
+Q L++++ + + +LR V+ A Q + LE AQ A
Sbjct: 1532 QRALQALEELRLQAEEAERRLRQAEVERA------------RQVQVALETAQRSAEA--- 1576
Query: 148 TPDSQTGKKLMAKCRMLIQENQELGRQLSQGR--IAQLEAELALQKKYSEELKSSQDELN 205
+L +K ++ +L R L + +AQL E + + E + +++E
Sbjct: 1577 --------ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREE-- 1626
Query: 206 DFIIQLDEEVEGMQ---STILVLQQQLKETRQQ----LAQYQQQQSQASAPSTSRTTASE 258
+ E+E Q + L L+ Q +E QQ A+ ++Q+ +A + R A E
Sbjct: 1627 -----AERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1681
Query: 259 -PVEQSEATSKDCSR 272
V Q E ++ +
Sbjct: 1682 QAVRQRELAEQELEK 1696
Score = 35.0 bits (79), Expect = 0.12
Identities = 60/285 (21%), Positives = 111/285 (38%), Gaps = 42/285 (14%)
Query: 25 ELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR-ENILVMRLATK 83
+L+ RW+ A + + L + RES + L Q++ RR E I M LA
Sbjct: 1183 QLLERWQAVLAQTDVRQRELEQLG-RQLRYYRESADPLGAWLQDARRRQEQIQAMPLADS 1241
Query: 84 EQEMQECTTQIQYLKQVQ---------QPSVAQLRSTMVDPAINLFFLKMKGE--LEQTK 132
+ ++ + L++++ Q Q + + D + L K + E K
Sbjct: 1242 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK 1301
Query: 133 DKLEQAQNELSAWKF-----------TPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIA 181
Q+ +E ++ T SQ K + R + +E + +Q ++ R
Sbjct: 1302 KPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER 1361
Query: 182 QLEAELALQKK------YSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQ 235
E E AL+K+ +++ ++ E + ++ EEV + + QQQ + +++
Sbjct: 1362 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1421
Query: 236 LAQYQQQQS--------QASAPSTSRTTASEPVE----QSEATSK 268
L Q +Q QA A SR E + Q EAT +
Sbjct: 1422 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATER 1466
Score = 34.7 bits (78), Expect = 0.15
Identities = 55/264 (20%), Positives = 105/264 (39%), Gaps = 31/264 (11%)
Query: 4 EEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLK 63
E+ L +K++ + ++ A EL+ + K+ L L+E +E++
Sbjct: 2309 EKMLKEKMQAVQEATRLKAEAELLQQQKE--------------LAQEQARRLQEDKEQMA 2354
Query: 64 QQQQESARRENILVMRLATKEQEMQECTTQIQYLK-QVQQPSVAQLRSTMVDPAINLFFL 122
QQ E + L + Q E + + + LK +V + S AQ R+ F
Sbjct: 2355 QQLAEETQG---FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR----FR 2407
Query: 123 KMKGELEQTKDKLEQAQNELSAWKFTPDSQT------GKKLMAKCRMLIQENQELGRQLS 176
K E+ + + E A E T + Q ++L L +E ++L ++
Sbjct: 2408 KQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAK 2467
Query: 177 QGRIAQLEAELALQKKYSEELKSSQDEL---NDFIIQLDEEVEGMQSTILVLQQQLKETR 233
++ E + Q++ +E ++ Q D ++Q + +E ++ + L Q
Sbjct: 2468 LLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKA 2527
Query: 234 QQLAQYQQQQSQASAPSTSRTTAS 257
QQL + QQ+Q Q R AS
Sbjct: 2528 QQLREEQQRQQQQMEQERQRLVAS 2551
Score = 29.6 bits (65), Expect = 5.0
Identities = 38/221 (17%), Positives = 90/221 (40%), Gaps = 20/221 (9%)
Query: 57 ESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPA 116
E EE+L +QQ+ R V K++++ E Q K + +L+ M +
Sbjct: 1345 EEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQ---AKAQAEREAKELQQRMQEEV 1401
Query: 117 INLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLS 176
+ + + + + Q EL + + +++ + AK R + R
Sbjct: 1402 V-----RREEAAVDAQQQKRSIQEELQQLRQSSEAE----IQAKARQAEAAERSRLRIEE 1452
Query: 177 QGRIAQLEAELALQKKYSEE-----LKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKE 231
+ R+ +L+ E +++ E L++ +E Q EE E ++ + Q+ ++
Sbjct: 1453 EIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ 1512
Query: 232 TRQQLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKDCSR 272
+LA + +++A + + A + +E+ +++ R
Sbjct: 1513 AEVELASRVKAEAEA---AREKQRALQALEELRLQAEEAER 1550
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 52.4 bits (124), Expect = 7e-07
Identities = 52/217 (23%), Positives = 99/217 (45%), Gaps = 20/217 (9%)
Query: 45 TDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPS 104
T+L + + L ++ E +QQ A R + L +++++Q+ +Q LK + +
Sbjct: 2388 TELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ-LKSEEMQT 2446
Query: 105 VAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRML 164
V Q + A+ FL K L Q + +EQ + +L Q + +AK + L
Sbjct: 2447 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE--------QLFQDEVAKAQQL 2498
Query: 165 IQENQELGRQLSQGR---IAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQST 221
+E Q +Q+ Q R +A +E Q + E ++ Q+EL QL+++ +
Sbjct: 2499 REEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQ----QLEQQRRQQEEL 2554
Query: 222 ILVLQQQLKETRQQLAQYQQQQSQASAPSTSRTTASE 258
+ Q+L+E Q L ++Q +A+ + TAS+
Sbjct: 2555 LAEENQRLREQLQLL----EEQHRAALAHSEEVTASQ 2587
Score = 43.5 bits (101), Expect = 3e-04
Identities = 55/275 (20%), Positives = 119/275 (43%), Gaps = 26/275 (9%)
Query: 1 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE 60
M EE L ++ R E + L + + EA+ QA RE++E
Sbjct: 1312 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQA-----------KAQAEREAKE 1360
Query: 61 KLKQQQQESARRENILVMRLATK---EQEMQEC--TTQIQYLKQVQQPSVAQLRSTMVDP 115
++ Q+E RRE V K ++E+Q+ +++ + + +Q A+ ++
Sbjct: 1361 LQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEE 1420
Query: 116 AINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQL 175
I + L +LE T+ + A+ EL A + + +K A+ +E + L RQ+
Sbjct: 1421 EIRVVRL----QLEATERQRGGAEGELQALRARAEEAEAQKRQAQ-----EEAERLRRQV 1471
Query: 176 SQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQ- 234
+ +AE+ L + E ++++++ + ++ ++ + Q +++ RQ
Sbjct: 1472 QDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQV 1531
Query: 235 QLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKD 269
Q+A Q+S + + R + +E Q E + ++
Sbjct: 1532 QVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1566
Score = 38.5 bits (88), Expect = 0.011
Identities = 48/231 (20%), Positives = 95/231 (41%), Gaps = 17/231 (7%)
Query: 52 VTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTT-QIQYLKQVQQPSVAQLRS 110
V LRE E+ QQQ E+ R L + + E ++Q + QQ S+AQ +
Sbjct: 1571 VAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEA 1630
Query: 111 TMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLI----Q 166
+ EQ + E A+ EL + + ++L A+ ++
Sbjct: 1631 EKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAET 1690
Query: 167 ENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQ 226
E E RQL + +A+L+ E A + +EL++ + ++ E+E + ++ +
Sbjct: 1691 EQGEQQRQLLEEELARLQREAAAATQKRQELEAE-------LAKVRAEMEVLLASKARAE 1743
Query: 227 QQLKETRQQLAQYQQQQS-----QASAPSTSRTTASEPVEQSEATSKDCSR 272
++ + T ++ Q + ++ A + R A E Q + +D +R
Sbjct: 1744 EESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAAR 1794
Score = 36.2 bits (82), Expect = 0.053
Identities = 49/255 (19%), Positives = 104/255 (40%), Gaps = 16/255 (6%)
Query: 22 ARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR----ENILV 77
A +E + K V+ L+ K + +ES +L+ Q+ + +R E
Sbjct: 1964 AEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHA 2023
Query: 78 MRLATKEQEMQECTTQIQ-YLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLE 136
+ KEQE+Q+ Q Q L Q++ + A R+ A +++ E E + + +
Sbjct: 2024 FAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA-----AEEAEEARVQAEREAAQSRRQ 2078
Query: 137 QAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQL------EAELALQ 190
+ E +Q + A L +E ++ + +Q A L +AE+
Sbjct: 2079 VEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKH 2138
Query: 191 KKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPS 250
KK++E+ + ++ + L ++E +L ++L+ + + + +Q+SQ
Sbjct: 2139 KKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEEL 2198
Query: 251 TSRTTASEPVEQSEA 265
S E + + +A
Sbjct: 2199 FSVRVQMEELSKLKA 2213
Score = 35.4 bits (80), Expect = 0.091
Identities = 56/255 (21%), Positives = 104/255 (40%), Gaps = 46/255 (18%)
Query: 34 EAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR---ENILVMRLATKEQEMQEC 90
E +QAL + + + E+E +Q Q ES R+ E L R+ + + +E
Sbjct: 1440 EGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK 1499
Query: 91 TTQIQYLKQVQ---QPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKF 147
+Q L++++ + + +LR V+ A Q + LE AQ A
Sbjct: 1500 QRALQALEELRLQAEEAERRLRQAEVERA------------RQVQVALETAQRSAEA--- 1544
Query: 148 TPDSQTGKKLMAKCRMLIQENQELGRQLSQGR--IAQLEAELALQKKYSEELKSSQDELN 205
+L +K ++ +L R L + +AQL E + + E + +++E
Sbjct: 1545 --------ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREE-- 1594
Query: 206 DFIIQLDEEVEGMQ---STILVLQQQLKETRQQ----LAQYQQQQSQASAPSTSRTTASE 258
+ E+E Q + L L+ Q +E QQ A+ ++Q+ +A + R A E
Sbjct: 1595 -----AERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1649
Query: 259 -PVEQSEATSKDCSR 272
V Q E ++ +
Sbjct: 1650 QAVRQRELAEQELEK 1664
Score = 35.0 bits (79), Expect = 0.12
Identities = 60/285 (21%), Positives = 111/285 (38%), Gaps = 42/285 (14%)
Query: 25 ELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR-ENILVMRLATK 83
+L+ RW+ A + + L + RES + L Q++ RR E I M LA
Sbjct: 1151 QLLERWQAVLAQTDVRQRELEQLG-RQLRYYRESADPLGAWLQDARRRQEQIQAMPLADS 1209
Query: 84 EQEMQECTTQIQYLKQVQ---------QPSVAQLRSTMVDPAINLFFLKMKGE--LEQTK 132
+ ++ + L++++ Q Q + + D + L K + E K
Sbjct: 1210 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK 1269
Query: 133 DKLEQAQNELSAWKF-----------TPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIA 181
Q+ +E ++ T SQ K + R + +E + +Q ++ R
Sbjct: 1270 KPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER 1329
Query: 182 QLEAELALQKK------YSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQ 235
E E AL+K+ +++ ++ E + ++ EEV + + QQQ + +++
Sbjct: 1330 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1389
Query: 236 LAQYQQQQS--------QASAPSTSRTTASEPVE----QSEATSK 268
L Q +Q QA A SR E + Q EAT +
Sbjct: 1390 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATER 1434
Score = 34.7 bits (78), Expect = 0.15
Identities = 55/264 (20%), Positives = 105/264 (39%), Gaps = 31/264 (11%)
Query: 4 EEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLK 63
E+ L +K++ + ++ A EL+ + K+ L L+E +E++
Sbjct: 2277 EKMLKEKMQAVQEATRLKAEAELLQQQKE--------------LAQEQARRLQEDKEQMA 2322
Query: 64 QQQQESARRENILVMRLATKEQEMQECTTQIQYLK-QVQQPSVAQLRSTMVDPAINLFFL 122
QQ E + L + Q E + + + LK +V + S AQ R+ F
Sbjct: 2323 QQLAEETQG---FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR----FR 2375
Query: 123 KMKGELEQTKDKLEQAQNELSAWKFTPDSQT------GKKLMAKCRMLIQENQELGRQLS 176
K E+ + + E A E T + Q ++L L +E ++L ++
Sbjct: 2376 KQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAK 2435
Query: 177 QGRIAQLEAELALQKKYSEELKSSQDEL---NDFIIQLDEEVEGMQSTILVLQQQLKETR 233
++ E + Q++ +E ++ Q D ++Q + +E ++ + L Q
Sbjct: 2436 LLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKA 2495
Query: 234 QQLAQYQQQQSQASAPSTSRTTAS 257
QQL + QQ+Q Q R AS
Sbjct: 2496 QQLREEQQRQQQQMEQERQRLVAS 2519
Score = 29.6 bits (65), Expect = 5.0
Identities = 38/221 (17%), Positives = 90/221 (40%), Gaps = 20/221 (9%)
Query: 57 ESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPA 116
E EE+L +QQ+ R V K++++ E Q K + +L+ M +
Sbjct: 1313 EEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQ---AKAQAEREAKELQQRMQEEV 1369
Query: 117 INLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLS 176
+ + + + + Q EL + + +++ + AK R + R
Sbjct: 1370 V-----RREEAAVDAQQQKRSIQEELQQLRQSSEAE----IQAKARQAEAAERSRLRIEE 1420
Query: 177 QGRIAQLEAELALQKKYSEE-----LKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKE 231
+ R+ +L+ E +++ E L++ +E Q EE E ++ + Q+ ++
Sbjct: 1421 EIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ 1480
Query: 232 TRQQLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKDCSR 272
+LA + +++A + + A + +E+ +++ R
Sbjct: 1481 AEVELASRVKAEAEA---AREKQRALQALEELRLQAEEAER 1518
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 52.4 bits (124), Expect = 7e-07
Identities = 52/217 (23%), Positives = 99/217 (45%), Gaps = 20/217 (9%)
Query: 45 TDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPS 104
T+L + + L ++ E +QQ A R + L +++++Q+ +Q LK + +
Sbjct: 2557 TELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ-LKSEEMQT 2615
Query: 105 VAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRML 164
V Q + A+ FL K L Q + +EQ + +L Q + +AK + L
Sbjct: 2616 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE--------QLFQDEVAKAQQL 2667
Query: 165 IQENQELGRQLSQGR---IAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQST 221
+E Q +Q+ Q R +A +E Q + E ++ Q+EL QL+++ +
Sbjct: 2668 REEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQ----QLEQQRRQQEEL 2723
Query: 222 ILVLQQQLKETRQQLAQYQQQQSQASAPSTSRTTASE 258
+ Q+L+E Q L ++Q +A+ + TAS+
Sbjct: 2724 LAEENQRLREQLQLL----EEQHRAALAHSEEVTASQ 2756
Score = 43.5 bits (101), Expect = 3e-04
Identities = 55/275 (20%), Positives = 119/275 (43%), Gaps = 26/275 (9%)
Query: 1 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE 60
M EE L ++ R E + L + + EA+ QA RE++E
Sbjct: 1481 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQA-----------KAQAEREAKE 1529
Query: 61 KLKQQQQESARRENILVMRLATK---EQEMQEC--TTQIQYLKQVQQPSVAQLRSTMVDP 115
++ Q+E RRE V K ++E+Q+ +++ + + +Q A+ ++
Sbjct: 1530 LQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEE 1589
Query: 116 AINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQL 175
I + L +LE T+ + A+ EL A + + +K A+ +E + L RQ+
Sbjct: 1590 EIRVVRL----QLEATERQRGGAEGELQALRARAEEAEAQKRQAQ-----EEAERLRRQV 1640
Query: 176 SQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQ- 234
+ +AE+ L + E ++++++ + ++ ++ + Q +++ RQ
Sbjct: 1641 QDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQV 1700
Query: 235 QLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKD 269
Q+A Q+S + + R + +E Q E + ++
Sbjct: 1701 QVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1735
Score = 38.5 bits (88), Expect = 0.011
Identities = 48/231 (20%), Positives = 95/231 (41%), Gaps = 17/231 (7%)
Query: 52 VTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTT-QIQYLKQVQQPSVAQLRS 110
V LRE E+ QQQ E+ R L + + E ++Q + QQ S+AQ +
Sbjct: 1740 VAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEA 1799
Query: 111 TMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLI----Q 166
+ EQ + E A+ EL + + ++L A+ ++
Sbjct: 1800 EKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAET 1859
Query: 167 ENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQ 226
E E RQL + +A+L+ E A + +EL++ + ++ E+E + ++ +
Sbjct: 1860 EQGEQQRQLLEEELARLQREAAAATQKRQELEAE-------LAKVRAEMEVLLASKARAE 1912
Query: 227 QQLKETRQQLAQYQQQQS-----QASAPSTSRTTASEPVEQSEATSKDCSR 272
++ + T ++ Q + ++ A + R A E Q + +D +R
Sbjct: 1913 EESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAAR 1963
Score = 36.2 bits (82), Expect = 0.053
Identities = 49/255 (19%), Positives = 104/255 (40%), Gaps = 16/255 (6%)
Query: 22 ARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR----ENILV 77
A +E + K V+ L+ K + +ES +L+ Q+ + +R E
Sbjct: 2133 AEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHA 2192
Query: 78 MRLATKEQEMQECTTQIQ-YLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLE 136
+ KEQE+Q+ Q Q L Q++ + A R+ A +++ E E + + +
Sbjct: 2193 FAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA-----AEEAEEARVQAEREAAQSRRQ 2247
Query: 137 QAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQL------EAELALQ 190
+ E +Q + A L +E ++ + +Q A L +AE+
Sbjct: 2248 VEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKH 2307
Query: 191 KKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPS 250
KK++E+ + ++ + L ++E +L ++L+ + + + +Q+SQ
Sbjct: 2308 KKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEEL 2367
Query: 251 TSRTTASEPVEQSEA 265
S E + + +A
Sbjct: 2368 FSVRVQMEELSKLKA 2382
Score = 35.4 bits (80), Expect = 0.091
Identities = 56/255 (21%), Positives = 104/255 (40%), Gaps = 46/255 (18%)
Query: 34 EAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR---ENILVMRLATKEQEMQEC 90
E +QAL + + + E+E +Q Q ES R+ E L R+ + + +E
Sbjct: 1609 EGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK 1668
Query: 91 TTQIQYLKQVQ---QPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKF 147
+Q L++++ + + +LR V+ A Q + LE AQ A
Sbjct: 1669 QRALQALEELRLQAEEAERRLRQAEVERA------------RQVQVALETAQRSAEA--- 1713
Query: 148 TPDSQTGKKLMAKCRMLIQENQELGRQLSQGR--IAQLEAELALQKKYSEELKSSQDELN 205
+L +K ++ +L R L + +AQL E + + E + +++E
Sbjct: 1714 --------ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREE-- 1763
Query: 206 DFIIQLDEEVEGMQ---STILVLQQQLKETRQQ----LAQYQQQQSQASAPSTSRTTASE 258
+ E+E Q + L L+ Q +E QQ A+ ++Q+ +A + R A E
Sbjct: 1764 -----AERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1818
Query: 259 -PVEQSEATSKDCSR 272
V Q E ++ +
Sbjct: 1819 QAVRQRELAEQELEK 1833
Score = 35.0 bits (79), Expect = 0.12
Identities = 60/285 (21%), Positives = 111/285 (38%), Gaps = 42/285 (14%)
Query: 25 ELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR-ENILVMRLATK 83
+L+ RW+ A + + L + RES + L Q++ RR E I M LA
Sbjct: 1320 QLLERWQAVLAQTDVRQRELEQLG-RQLRYYRESADPLGAWLQDARRRQEQIQAMPLADS 1378
Query: 84 EQEMQECTTQIQYLKQVQ---------QPSVAQLRSTMVDPAINLFFLKMKGE--LEQTK 132
+ ++ + L++++ Q Q + + D + L K + E K
Sbjct: 1379 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK 1438
Query: 133 DKLEQAQNELSAWKF-----------TPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIA 181
Q+ +E ++ T SQ K + R + +E + +Q ++ R
Sbjct: 1439 KPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER 1498
Query: 182 QLEAELALQKK------YSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQ 235
E E AL+K+ +++ ++ E + ++ EEV + + QQQ + +++
Sbjct: 1499 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1558
Query: 236 LAQYQQQQS--------QASAPSTSRTTASEPVE----QSEATSK 268
L Q +Q QA A SR E + Q EAT +
Sbjct: 1559 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATER 1603
Score = 34.7 bits (78), Expect = 0.15
Identities = 55/264 (20%), Positives = 105/264 (39%), Gaps = 31/264 (11%)
Query: 4 EEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLK 63
E+ L +K++ + ++ A EL+ + K+ L L+E +E++
Sbjct: 2446 EKMLKEKMQAVQEATRLKAEAELLQQQKE--------------LAQEQARRLQEDKEQMA 2491
Query: 64 QQQQESARRENILVMRLATKEQEMQECTTQIQYLK-QVQQPSVAQLRSTMVDPAINLFFL 122
QQ E + L + Q E + + + LK +V + S AQ R+ F
Sbjct: 2492 QQLAEETQG---FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR----FR 2544
Query: 123 KMKGELEQTKDKLEQAQNELSAWKFTPDSQT------GKKLMAKCRMLIQENQELGRQLS 176
K E+ + + E A E T + Q ++L L +E ++L ++
Sbjct: 2545 KQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAK 2604
Query: 177 QGRIAQLEAELALQKKYSEELKSSQDEL---NDFIIQLDEEVEGMQSTILVLQQQLKETR 233
++ E + Q++ +E ++ Q D ++Q + +E ++ + L Q
Sbjct: 2605 LLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKA 2664
Query: 234 QQLAQYQQQQSQASAPSTSRTTAS 257
QQL + QQ+Q Q R AS
Sbjct: 2665 QQLREEQQRQQQQMEQERQRLVAS 2688
Score = 29.6 bits (65), Expect = 5.0
Identities = 38/221 (17%), Positives = 90/221 (40%), Gaps = 20/221 (9%)
Query: 57 ESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPA 116
E EE+L +QQ+ R V K++++ E Q K + +L+ M +
Sbjct: 1482 EEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQ---AKAQAEREAKELQQRMQEEV 1538
Query: 117 INLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLS 176
+ + + + + Q EL + + +++ + AK R + R
Sbjct: 1539 V-----RREEAAVDAQQQKRSIQEELQQLRQSSEAE----IQAKARQAEAAERSRLRIEE 1589
Query: 177 QGRIAQLEAELALQKKYSEE-----LKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKE 231
+ R+ +L+ E +++ E L++ +E Q EE E ++ + Q+ ++
Sbjct: 1590 EIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ 1649
Query: 232 TRQQLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKDCSR 272
+LA + +++A + + A + +E+ +++ R
Sbjct: 1650 AEVELASRVKAEAEA---AREKQRALQALEELRLQAEEAER 1687
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 52.4 bits (124), Expect = 7e-07
Identities = 52/217 (23%), Positives = 99/217 (45%), Gaps = 20/217 (9%)
Query: 45 TDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPS 104
T+L + + L ++ E +QQ A R + L +++++Q+ +Q LK + +
Sbjct: 2398 TELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ-LKSEEMQT 2456
Query: 105 VAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRML 164
V Q + A+ FL K L Q + +EQ + +L Q + +AK + L
Sbjct: 2457 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE--------QLFQDEVAKAQQL 2508
Query: 165 IQENQELGRQLSQGR---IAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQST 221
+E Q +Q+ Q R +A +E Q + E ++ Q+EL QL+++ +
Sbjct: 2509 REEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQ----QLEQQRRQQEEL 2564
Query: 222 ILVLQQQLKETRQQLAQYQQQQSQASAPSTSRTTASE 258
+ Q+L+E Q L ++Q +A+ + TAS+
Sbjct: 2565 LAEENQRLREQLQLL----EEQHRAALAHSEEVTASQ 2597
Score = 43.5 bits (101), Expect = 3e-04
Identities = 55/275 (20%), Positives = 119/275 (43%), Gaps = 26/275 (9%)
Query: 1 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE 60
M EE L ++ R E + L + + EA+ QA RE++E
Sbjct: 1322 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQA-----------KAQAEREAKE 1370
Query: 61 KLKQQQQESARRENILVMRLATK---EQEMQEC--TTQIQYLKQVQQPSVAQLRSTMVDP 115
++ Q+E RRE V K ++E+Q+ +++ + + +Q A+ ++
Sbjct: 1371 LQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEE 1430
Query: 116 AINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQL 175
I + L +LE T+ + A+ EL A + + +K A+ +E + L RQ+
Sbjct: 1431 EIRVVRL----QLEATERQRGGAEGELQALRARAEEAEAQKRQAQ-----EEAERLRRQV 1481
Query: 176 SQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQ- 234
+ +AE+ L + E ++++++ + ++ ++ + Q +++ RQ
Sbjct: 1482 QDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQV 1541
Query: 235 QLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKD 269
Q+A Q+S + + R + +E Q E + ++
Sbjct: 1542 QVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1576
Score = 38.5 bits (88), Expect = 0.011
Identities = 48/231 (20%), Positives = 95/231 (41%), Gaps = 17/231 (7%)
Query: 52 VTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTT-QIQYLKQVQQPSVAQLRS 110
V LRE E+ QQQ E+ R L + + E ++Q + QQ S+AQ +
Sbjct: 1581 VAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEA 1640
Query: 111 TMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLI----Q 166
+ EQ + E A+ EL + + ++L A+ ++
Sbjct: 1641 EKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAET 1700
Query: 167 ENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQ 226
E E RQL + +A+L+ E A + +EL++ + ++ E+E + ++ +
Sbjct: 1701 EQGEQQRQLLEEELARLQREAAAATQKRQELEAE-------LAKVRAEMEVLLASKARAE 1753
Query: 227 QQLKETRQQLAQYQQQQS-----QASAPSTSRTTASEPVEQSEATSKDCSR 272
++ + T ++ Q + ++ A + R A E Q + +D +R
Sbjct: 1754 EESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAAR 1804
Score = 36.2 bits (82), Expect = 0.053
Identities = 49/255 (19%), Positives = 104/255 (40%), Gaps = 16/255 (6%)
Query: 22 ARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR----ENILV 77
A +E + K V+ L+ K + +ES +L+ Q+ + +R E
Sbjct: 1974 AEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHA 2033
Query: 78 MRLATKEQEMQECTTQIQ-YLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLE 136
+ KEQE+Q+ Q Q L Q++ + A R+ A +++ E E + + +
Sbjct: 2034 FAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA-----AEEAEEARVQAEREAAQSRRQ 2088
Query: 137 QAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQL------EAELALQ 190
+ E +Q + A L +E ++ + +Q A L +AE+
Sbjct: 2089 VEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKH 2148
Query: 191 KKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPS 250
KK++E+ + ++ + L ++E +L ++L+ + + + +Q+SQ
Sbjct: 2149 KKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEEL 2208
Query: 251 TSRTTASEPVEQSEA 265
S E + + +A
Sbjct: 2209 FSVRVQMEELSKLKA 2223
Score = 35.4 bits (80), Expect = 0.091
Identities = 56/255 (21%), Positives = 104/255 (40%), Gaps = 46/255 (18%)
Query: 34 EAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR---ENILVMRLATKEQEMQEC 90
E +QAL + + + E+E +Q Q ES R+ E L R+ + + +E
Sbjct: 1450 EGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK 1509
Query: 91 TTQIQYLKQVQ---QPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKF 147
+Q L++++ + + +LR V+ A Q + LE AQ A
Sbjct: 1510 QRALQALEELRLQAEEAERRLRQAEVERA------------RQVQVALETAQRSAEA--- 1554
Query: 148 TPDSQTGKKLMAKCRMLIQENQELGRQLSQGR--IAQLEAELALQKKYSEELKSSQDELN 205
+L +K ++ +L R L + +AQL E + + E + +++E
Sbjct: 1555 --------ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREE-- 1604
Query: 206 DFIIQLDEEVEGMQ---STILVLQQQLKETRQQ----LAQYQQQQSQASAPSTSRTTASE 258
+ E+E Q + L L+ Q +E QQ A+ ++Q+ +A + R A E
Sbjct: 1605 -----AERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1659
Query: 259 -PVEQSEATSKDCSR 272
V Q E ++ +
Sbjct: 1660 QAVRQRELAEQELEK 1674
Score = 35.0 bits (79), Expect = 0.12
Identities = 60/285 (21%), Positives = 111/285 (38%), Gaps = 42/285 (14%)
Query: 25 ELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR-ENILVMRLATK 83
+L+ RW+ A + + L + RES + L Q++ RR E I M LA
Sbjct: 1161 QLLERWQAVLAQTDVRQRELEQLG-RQLRYYRESADPLGAWLQDARRRQEQIQAMPLADS 1219
Query: 84 EQEMQECTTQIQYLKQVQ---------QPSVAQLRSTMVDPAINLFFLKMKGE--LEQTK 132
+ ++ + L++++ Q Q + + D + L K + E K
Sbjct: 1220 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK 1279
Query: 133 DKLEQAQNELSAWKF-----------TPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIA 181
Q+ +E ++ T SQ K + R + +E + +Q ++ R
Sbjct: 1280 KPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER 1339
Query: 182 QLEAELALQKK------YSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQ 235
E E AL+K+ +++ ++ E + ++ EEV + + QQQ + +++
Sbjct: 1340 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1399
Query: 236 LAQYQQQQS--------QASAPSTSRTTASEPVE----QSEATSK 268
L Q +Q QA A SR E + Q EAT +
Sbjct: 1400 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATER 1444
Score = 34.7 bits (78), Expect = 0.15
Identities = 55/264 (20%), Positives = 105/264 (39%), Gaps = 31/264 (11%)
Query: 4 EEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLK 63
E+ L +K++ + ++ A EL+ + K+ L L+E +E++
Sbjct: 2287 EKMLKEKMQAVQEATRLKAEAELLQQQKE--------------LAQEQARRLQEDKEQMA 2332
Query: 64 QQQQESARRENILVMRLATKEQEMQECTTQIQYLK-QVQQPSVAQLRSTMVDPAINLFFL 122
QQ E + L + Q E + + + LK +V + S AQ R+ F
Sbjct: 2333 QQLAEETQG---FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR----FR 2385
Query: 123 KMKGELEQTKDKLEQAQNELSAWKFTPDSQT------GKKLMAKCRMLIQENQELGRQLS 176
K E+ + + E A E T + Q ++L L +E ++L ++
Sbjct: 2386 KQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAK 2445
Query: 177 QGRIAQLEAELALQKKYSEELKSSQDEL---NDFIIQLDEEVEGMQSTILVLQQQLKETR 233
++ E + Q++ +E ++ Q D ++Q + +E ++ + L Q
Sbjct: 2446 LLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKA 2505
Query: 234 QQLAQYQQQQSQASAPSTSRTTAS 257
QQL + QQ+Q Q R AS
Sbjct: 2506 QQLREEQQRQQQQMEQERQRLVAS 2529
Score = 29.6 bits (65), Expect = 5.0
Identities = 38/221 (17%), Positives = 90/221 (40%), Gaps = 20/221 (9%)
Query: 57 ESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPA 116
E EE+L +QQ+ R V K++++ E Q K + +L+ M +
Sbjct: 1323 EEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQ---AKAQAEREAKELQQRMQEEV 1379
Query: 117 INLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLS 176
+ + + + + Q EL + + +++ + AK R + R
Sbjct: 1380 V-----RREEAAVDAQQQKRSIQEELQQLRQSSEAE----IQAKARQAEAAERSRLRIEE 1430
Query: 177 QGRIAQLEAELALQKKYSEE-----LKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKE 231
+ R+ +L+ E +++ E L++ +E Q EE E ++ + Q+ ++
Sbjct: 1431 EIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ 1490
Query: 232 TRQQLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKDCSR 272
+LA + +++A + + A + +E+ +++ R
Sbjct: 1491 AEVELASRVKAEAEA---AREKQRALQALEELRLQAEEAER 1528
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 52.4 bits (124), Expect = 7e-07
Identities = 52/217 (23%), Positives = 99/217 (45%), Gaps = 20/217 (9%)
Query: 45 TDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPS 104
T+L + + L ++ E +QQ A R + L +++++Q+ +Q LK + +
Sbjct: 2406 TELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ-LKSEEMQT 2464
Query: 105 VAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRML 164
V Q + A+ FL K L Q + +EQ + +L Q + +AK + L
Sbjct: 2465 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE--------QLFQDEVAKAQQL 2516
Query: 165 IQENQELGRQLSQGR---IAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQST 221
+E Q +Q+ Q R +A +E Q + E ++ Q+EL QL+++ +
Sbjct: 2517 REEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQ----QLEQQRRQQEEL 2572
Query: 222 ILVLQQQLKETRQQLAQYQQQQSQASAPSTSRTTASE 258
+ Q+L+E Q L ++Q +A+ + TAS+
Sbjct: 2573 LAEENQRLREQLQLL----EEQHRAALAHSEEVTASQ 2605
Score = 43.5 bits (101), Expect = 3e-04
Identities = 55/275 (20%), Positives = 119/275 (43%), Gaps = 26/275 (9%)
Query: 1 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE 60
M EE L ++ R E + L + + EA+ QA RE++E
Sbjct: 1330 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQA-----------KAQAEREAKE 1378
Query: 61 KLKQQQQESARRENILVMRLATK---EQEMQEC--TTQIQYLKQVQQPSVAQLRSTMVDP 115
++ Q+E RRE V K ++E+Q+ +++ + + +Q A+ ++
Sbjct: 1379 LQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEE 1438
Query: 116 AINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQL 175
I + L +LE T+ + A+ EL A + + +K A+ +E + L RQ+
Sbjct: 1439 EIRVVRL----QLEATERQRGGAEGELQALRARAEEAEAQKRQAQ-----EEAERLRRQV 1489
Query: 176 SQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQ- 234
+ +AE+ L + E ++++++ + ++ ++ + Q +++ RQ
Sbjct: 1490 QDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQV 1549
Query: 235 QLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKD 269
Q+A Q+S + + R + +E Q E + ++
Sbjct: 1550 QVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1584
Score = 38.5 bits (88), Expect = 0.011
Identities = 48/231 (20%), Positives = 95/231 (41%), Gaps = 17/231 (7%)
Query: 52 VTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTT-QIQYLKQVQQPSVAQLRS 110
V LRE E+ QQQ E+ R L + + E ++Q + QQ S+AQ +
Sbjct: 1589 VAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEA 1648
Query: 111 TMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLI----Q 166
+ EQ + E A+ EL + + ++L A+ ++
Sbjct: 1649 EKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAET 1708
Query: 167 ENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQ 226
E E RQL + +A+L+ E A + +EL++ + ++ E+E + ++ +
Sbjct: 1709 EQGEQQRQLLEEELARLQREAAAATQKRQELEAE-------LAKVRAEMEVLLASKARAE 1761
Query: 227 QQLKETRQQLAQYQQQQS-----QASAPSTSRTTASEPVEQSEATSKDCSR 272
++ + T ++ Q + ++ A + R A E Q + +D +R
Sbjct: 1762 EESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAAR 1812
Score = 36.2 bits (82), Expect = 0.053
Identities = 49/255 (19%), Positives = 104/255 (40%), Gaps = 16/255 (6%)
Query: 22 ARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR----ENILV 77
A +E + K V+ L+ K + +ES +L+ Q+ + +R E
Sbjct: 1982 AEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHA 2041
Query: 78 MRLATKEQEMQECTTQIQ-YLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLE 136
+ KEQE+Q+ Q Q L Q++ + A R+ A +++ E E + + +
Sbjct: 2042 FAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA-----AEEAEEARVQAEREAAQSRRQ 2096
Query: 137 QAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQL------EAELALQ 190
+ E +Q + A L +E ++ + +Q A L +AE+
Sbjct: 2097 VEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKH 2156
Query: 191 KKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPS 250
KK++E+ + ++ + L ++E +L ++L+ + + + +Q+SQ
Sbjct: 2157 KKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEEL 2216
Query: 251 TSRTTASEPVEQSEA 265
S E + + +A
Sbjct: 2217 FSVRVQMEELSKLKA 2231
Score = 35.4 bits (80), Expect = 0.091
Identities = 56/255 (21%), Positives = 104/255 (40%), Gaps = 46/255 (18%)
Query: 34 EAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR---ENILVMRLATKEQEMQEC 90
E +QAL + + + E+E +Q Q ES R+ E L R+ + + +E
Sbjct: 1458 EGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK 1517
Query: 91 TTQIQYLKQVQ---QPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKF 147
+Q L++++ + + +LR V+ A Q + LE AQ A
Sbjct: 1518 QRALQALEELRLQAEEAERRLRQAEVERA------------RQVQVALETAQRSAEA--- 1562
Query: 148 TPDSQTGKKLMAKCRMLIQENQELGRQLSQGR--IAQLEAELALQKKYSEELKSSQDELN 205
+L +K ++ +L R L + +AQL E + + E + +++E
Sbjct: 1563 --------ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREE-- 1612
Query: 206 DFIIQLDEEVEGMQ---STILVLQQQLKETRQQ----LAQYQQQQSQASAPSTSRTTASE 258
+ E+E Q + L L+ Q +E QQ A+ ++Q+ +A + R A E
Sbjct: 1613 -----AERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1667
Query: 259 -PVEQSEATSKDCSR 272
V Q E ++ +
Sbjct: 1668 QAVRQRELAEQELEK 1682
Score = 35.0 bits (79), Expect = 0.12
Identities = 60/285 (21%), Positives = 111/285 (38%), Gaps = 42/285 (14%)
Query: 25 ELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR-ENILVMRLATK 83
+L+ RW+ A + + L + RES + L Q++ RR E I M LA
Sbjct: 1169 QLLERWQAVLAQTDVRQRELEQLG-RQLRYYRESADPLGAWLQDARRRQEQIQAMPLADS 1227
Query: 84 EQEMQECTTQIQYLKQVQ---------QPSVAQLRSTMVDPAINLFFLKMKGE--LEQTK 132
+ ++ + L++++ Q Q + + D + L K + E K
Sbjct: 1228 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK 1287
Query: 133 DKLEQAQNELSAWKF-----------TPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIA 181
Q+ +E ++ T SQ K + R + +E + +Q ++ R
Sbjct: 1288 KPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER 1347
Query: 182 QLEAELALQKK------YSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQ 235
E E AL+K+ +++ ++ E + ++ EEV + + QQQ + +++
Sbjct: 1348 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1407
Query: 236 LAQYQQQQS--------QASAPSTSRTTASEPVE----QSEATSK 268
L Q +Q QA A SR E + Q EAT +
Sbjct: 1408 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATER 1452
Score = 34.7 bits (78), Expect = 0.15
Identities = 55/264 (20%), Positives = 105/264 (39%), Gaps = 31/264 (11%)
Query: 4 EEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLK 63
E+ L +K++ + ++ A EL+ + K+ L L+E +E++
Sbjct: 2295 EKMLKEKMQAVQEATRLKAEAELLQQQKE--------------LAQEQARRLQEDKEQMA 2340
Query: 64 QQQQESARRENILVMRLATKEQEMQECTTQIQYLK-QVQQPSVAQLRSTMVDPAINLFFL 122
QQ E + L + Q E + + + LK +V + S AQ R+ F
Sbjct: 2341 QQLAEETQG---FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR----FR 2393
Query: 123 KMKGELEQTKDKLEQAQNELSAWKFTPDSQT------GKKLMAKCRMLIQENQELGRQLS 176
K E+ + + E A E T + Q ++L L +E ++L ++
Sbjct: 2394 KQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAK 2453
Query: 177 QGRIAQLEAELALQKKYSEELKSSQDEL---NDFIIQLDEEVEGMQSTILVLQQQLKETR 233
++ E + Q++ +E ++ Q D ++Q + +E ++ + L Q
Sbjct: 2454 LLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKA 2513
Query: 234 QQLAQYQQQQSQASAPSTSRTTAS 257
QQL + QQ+Q Q R AS
Sbjct: 2514 QQLREEQQRQQQQMEQERQRLVAS 2537
Score = 29.6 bits (65), Expect = 5.0
Identities = 38/221 (17%), Positives = 90/221 (40%), Gaps = 20/221 (9%)
Query: 57 ESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPA 116
E EE+L +QQ+ R V K++++ E Q K + +L+ M +
Sbjct: 1331 EEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQ---AKAQAEREAKELQQRMQEEV 1387
Query: 117 INLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLS 176
+ + + + + Q EL + + +++ + AK R + R
Sbjct: 1388 V-----RREEAAVDAQQQKRSIQEELQQLRQSSEAE----IQAKARQAEAAERSRLRIEE 1438
Query: 177 QGRIAQLEAELALQKKYSEE-----LKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKE 231
+ R+ +L+ E +++ E L++ +E Q EE E ++ + Q+ ++
Sbjct: 1439 EIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ 1498
Query: 232 TRQQLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKDCSR 272
+LA + +++A + + A + +E+ +++ R
Sbjct: 1499 AEVELASRVKAEAEA---AREKQRALQALEELRLQAEEAER 1536
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 52.4 bits (124), Expect = 7e-07
Identities = 52/217 (23%), Positives = 99/217 (45%), Gaps = 20/217 (9%)
Query: 45 TDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPS 104
T+L + + L ++ E +QQ A R + L +++++Q+ +Q LK + +
Sbjct: 2447 TELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ-LKSEEMQT 2505
Query: 105 VAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRML 164
V Q + A+ FL K L Q + +EQ + +L Q + +AK + L
Sbjct: 2506 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLE--------QLFQDEVAKAQQL 2557
Query: 165 IQENQELGRQLSQGR---IAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQST 221
+E Q +Q+ Q R +A +E Q + E ++ Q+EL QL+++ +
Sbjct: 2558 REEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQ----QLEQQRRQQEEL 2613
Query: 222 ILVLQQQLKETRQQLAQYQQQQSQASAPSTSRTTASE 258
+ Q+L+E Q L ++Q +A+ + TAS+
Sbjct: 2614 LAEENQRLREQLQLL----EEQHRAALAHSEEVTASQ 2646
Score = 43.5 bits (101), Expect = 3e-04
Identities = 55/275 (20%), Positives = 119/275 (43%), Gaps = 26/275 (9%)
Query: 1 MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEE 60
M EE L ++ R E + L + + EA+ QA RE++E
Sbjct: 1371 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQA-----------KAQAEREAKE 1419
Query: 61 KLKQQQQESARRENILVMRLATK---EQEMQEC--TTQIQYLKQVQQPSVAQLRSTMVDP 115
++ Q+E RRE V K ++E+Q+ +++ + + +Q A+ ++
Sbjct: 1420 LQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEE 1479
Query: 116 AINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQL 175
I + L +LE T+ + A+ EL A + + +K A+ +E + L RQ+
Sbjct: 1480 EIRVVRL----QLEATERQRGGAEGELQALRARAEEAEAQKRQAQ-----EEAERLRRQV 1530
Query: 176 SQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQ- 234
+ +AE+ L + E ++++++ + ++ ++ + Q +++ RQ
Sbjct: 1531 QDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQV 1590
Query: 235 QLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKD 269
Q+A Q+S + + R + +E Q E + ++
Sbjct: 1591 QVALETAQRSAEAELQSKRASFAEKTAQLERSLQE 1625
Score = 38.5 bits (88), Expect = 0.011
Identities = 48/231 (20%), Positives = 95/231 (41%), Gaps = 17/231 (7%)
Query: 52 VTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTT-QIQYLKQVQQPSVAQLRS 110
V LRE E+ QQQ E+ R L + + E ++Q + QQ S+AQ +
Sbjct: 1630 VAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEA 1689
Query: 111 TMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLI----Q 166
+ EQ + E A+ EL + + ++L A+ ++
Sbjct: 1690 EKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAET 1749
Query: 167 ENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQ 226
E E RQL + +A+L+ E A + +EL++ + ++ E+E + ++ +
Sbjct: 1750 EQGEQQRQLLEEELARLQREAAAATQKRQELEAE-------LAKVRAEMEVLLASKARAE 1802
Query: 227 QQLKETRQQLAQYQQQQS-----QASAPSTSRTTASEPVEQSEATSKDCSR 272
++ + T ++ Q + ++ A + R A E Q + +D +R
Sbjct: 1803 EESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAAR 1853
Score = 36.2 bits (82), Expect = 0.053
Identities = 49/255 (19%), Positives = 104/255 (40%), Gaps = 16/255 (6%)
Query: 22 ARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR----ENILV 77
A +E + K V+ L+ K + +ES +L+ Q+ + +R E
Sbjct: 2023 AEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHA 2082
Query: 78 MRLATKEQEMQECTTQIQ-YLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLE 136
+ KEQE+Q+ Q Q L Q++ + A R+ A +++ E E + + +
Sbjct: 2083 FAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA-----AEEAEEARVQAEREAAQSRRQ 2137
Query: 137 QAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQL------EAELALQ 190
+ E +Q + A L +E ++ + +Q A L +AE+
Sbjct: 2138 VEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKH 2197
Query: 191 KKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPS 250
KK++E+ + ++ + L ++E +L ++L+ + + + +Q+SQ
Sbjct: 2198 KKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEEL 2257
Query: 251 TSRTTASEPVEQSEA 265
S E + + +A
Sbjct: 2258 FSVRVQMEELSKLKA 2272
Score = 35.4 bits (80), Expect = 0.091
Identities = 56/255 (21%), Positives = 104/255 (40%), Gaps = 46/255 (18%)
Query: 34 EAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR---ENILVMRLATKEQEMQEC 90
E +QAL + + + E+E +Q Q ES R+ E L R+ + + +E
Sbjct: 1499 EGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREK 1558
Query: 91 TTQIQYLKQVQ---QPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKF 147
+Q L++++ + + +LR V+ A Q + LE AQ A
Sbjct: 1559 QRALQALEELRLQAEEAERRLRQAEVERA------------RQVQVALETAQRSAEA--- 1603
Query: 148 TPDSQTGKKLMAKCRMLIQENQELGRQLSQGR--IAQLEAELALQKKYSEELKSSQDELN 205
+L +K ++ +L R L + +AQL E + + E + +++E
Sbjct: 1604 --------ELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREE-- 1653
Query: 206 DFIIQLDEEVEGMQ---STILVLQQQLKETRQQ----LAQYQQQQSQASAPSTSRTTASE 258
+ E+E Q + L L+ Q +E QQ A+ ++Q+ +A + R A E
Sbjct: 1654 -----AERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEE 1708
Query: 259 -PVEQSEATSKDCSR 272
V Q E ++ +
Sbjct: 1709 QAVRQRELAEQELEK 1723
Score = 35.0 bits (79), Expect = 0.12
Identities = 60/285 (21%), Positives = 111/285 (38%), Gaps = 42/285 (14%)
Query: 25 ELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR-ENILVMRLATK 83
+L+ RW+ A + + L + RES + L Q++ RR E I M LA
Sbjct: 1210 QLLERWQAVLAQTDVRQRELEQLG-RQLRYYRESADPLGAWLQDARRRQEQIQAMPLADS 1268
Query: 84 EQEMQECTTQIQYLKQVQ---------QPSVAQLRSTMVDPAINLFFLKMKGE--LEQTK 132
+ ++ + L++++ Q Q + + D + L K + E K
Sbjct: 1269 QAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAK 1328
Query: 133 DKLEQAQNELSAWKF-----------TPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIA 181
Q+ +E ++ T SQ K + R + +E + +Q ++ R
Sbjct: 1329 KPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERER 1388
Query: 182 QLEAELALQKK------YSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQ 235
E E AL+K+ +++ ++ E + ++ EEV + + QQQ + +++
Sbjct: 1389 LAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEE 1448
Query: 236 LAQYQQQQS--------QASAPSTSRTTASEPVE----QSEATSK 268
L Q +Q QA A SR E + Q EAT +
Sbjct: 1449 LQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATER 1493
Score = 34.7 bits (78), Expect = 0.15
Identities = 55/264 (20%), Positives = 105/264 (39%), Gaps = 31/264 (11%)
Query: 4 EEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLK 63
E+ L +K++ + ++ A EL+ + K+ L L+E +E++
Sbjct: 2336 EKMLKEKMQAVQEATRLKAEAELLQQQKE--------------LAQEQARRLQEDKEQMA 2381
Query: 64 QQQQESARRENILVMRLATKEQEMQECTTQIQYLK-QVQQPSVAQLRSTMVDPAINLFFL 122
QQ E + L + Q E + + + LK +V + S AQ R+ F
Sbjct: 2382 QQLAEETQG---FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR----FR 2434
Query: 123 KMKGELEQTKDKLEQAQNELSAWKFTPDSQT------GKKLMAKCRMLIQENQELGRQLS 176
K E+ + + E A E T + Q ++L L +E ++L ++
Sbjct: 2435 KQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAK 2494
Query: 177 QGRIAQLEAELALQKKYSEELKSSQDEL---NDFIIQLDEEVEGMQSTILVLQQQLKETR 233
++ E + Q++ +E ++ Q D ++Q + +E ++ + L Q
Sbjct: 2495 LLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKA 2554
Query: 234 QQLAQYQQQQSQASAPSTSRTTAS 257
QQL + QQ+Q Q R AS
Sbjct: 2555 QQLREEQQRQQQQMEQERQRLVAS 2578
Score = 29.6 bits (65), Expect = 5.0
Identities = 38/221 (17%), Positives = 90/221 (40%), Gaps = 20/221 (9%)
Query: 57 ESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPA 116
E EE+L +QQ+ R V K++++ E Q K + +L+ M +
Sbjct: 1372 EEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQ---AKAQAEREAKELQQRMQEEV 1428
Query: 117 INLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLS 176
+ + + + + Q EL + + +++ + AK R + R
Sbjct: 1429 V-----RREEAAVDAQQQKRSIQEELQQLRQSSEAE----IQAKARQAEAAERSRLRIEE 1479
Query: 177 QGRIAQLEAELALQKKYSEE-----LKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKE 231
+ R+ +L+ E +++ E L++ +E Q EE E ++ + Q+ ++
Sbjct: 1480 EIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ 1539
Query: 232 TRQQLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKDCSR 272
+LA + +++A + + A + +E+ +++ R
Sbjct: 1540 AEVELASRVKAEAEA---AREKQRALQALEELRLQAEEAER 1577
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 50.8 bits (120), Expect = 2e-06
Identities = 63/253 (24%), Positives = 112/253 (44%), Gaps = 38/253 (15%)
Query: 40 LEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQ 99
L K+ + + E E+KLK++++ + EN +V Q ++C+ LKQ
Sbjct: 698 LTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVV-------QIEKQCSMLDVDLKQ 750
Query: 100 VQQ--PSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTG--K 155
QQ + + M D NL +LEQ +K QNEL F D+ G K
Sbjct: 751 SQQKLEHLTGNKERMEDEVKNLTL-----QLEQESNKRLLLQNELKTQAFEADNLKGLEK 805
Query: 156 KLMAKCRMLIQENQELGRQLSQ---------GRIAQLEAELALQKKYS-------EELKS 199
++ + L++ + L +L+Q G++ +L+ +L ++ +S +ELK
Sbjct: 806 QMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKE 865
Query: 200 SQDELNDFIIQLDEEVEGMQSTILVLQQQLKETR---QQLAQYQQQQSQASAPSTSRTTA 256
+E N ++ +E++ + T L Q L ET+ +QLA+ ++ S+ A
Sbjct: 866 EIEEKNRENLKKIQELQNEKET-LATQLDLAETKAESEQLARGLLEEQYFELTQESKKAA 924
Query: 257 SEPVEQSEATSKD 269
S + E T KD
Sbjct: 925 SR--NRQEITDKD 935
Score = 33.9 bits (76), Expect = 0.26
Identities = 42/211 (19%), Positives = 88/211 (41%), Gaps = 26/211 (12%)
Query: 40 LEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQ 99
LE + + + E ++ +QE+ +R N+ E E+ Q++ LK+
Sbjct: 477 LESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNV--------ENEVSTLKDQLEDLKK 528
Query: 100 VQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMA 159
V Q S QL + + +++ +LE+ D L + +A + K ++
Sbjct: 529 VSQNS--QLANEKLS--------QLQKQLEEANDLLRTESD--TAVRLRKSHTEMSKSIS 576
Query: 160 KCRMLIQENQELGRQLSQGRIA------QLEAELALQKKYSEELKSSQDELNDFIIQLDE 213
+ L +E QE R L + QL+A L +++ +L I L E
Sbjct: 577 QLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQE 636
Query: 214 EVEGMQSTILVLQQQLKETRQQLAQYQQQQS 244
EV+ ++ + ++ + KE + L +++++
Sbjct: 637 EVKHLKHNLEKVEGERKEAQDMLNHSEKEKN 667
Score = 32.7 bits (73), Expect = 0.59
Identities = 47/240 (19%), Positives = 96/240 (40%), Gaps = 41/240 (17%)
Query: 40 LEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQ 99
LE +Y +L +ES++ + +QE +++ V RL E+ T I+ L++
Sbjct: 909 LEEQYFELT-------QESKKAASRNRQEITDKDHT-VSRL---EEANSMLTKDIEILRR 957
Query: 100 VQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMA 159
+ +++ K E E +K E+ N +A++ +++ K A
Sbjct: 958 ENEELTEKMK---------------KAEEEYKLEKEEEISNLKAAFEKNINTERTLKTQA 1002
Query: 160 KCRML-IQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGM 218
++ I ++ + L + +K EL +++ N +++ +E+ M
Sbjct: 1003 VNKLAEIMNRKDFKIDRKKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDM 1062
Query: 219 QSTIL-------VLQQQL-------KETRQQLAQYQQQQSQASAPSTSRTTASEPVEQSE 264
Q+ ++ LQ QL ++ R +L S AS PS T + P + E
Sbjct: 1063 QAQLVEECAHRNELQMQLASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIE 1122
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 50.8 bits (120), Expect = 2e-06
Identities = 64/277 (23%), Positives = 128/277 (46%), Gaps = 53/277 (19%)
Query: 10 KVRLSETDFKVMARDELILRWKQYEAYVQALEGKYT-DLNSNDVTGLRESEEKLKQQQQ- 67
K +L E + ++ A ++ LR E +QAL+G++ DL + D ++EEK +Q Q+
Sbjct: 1545 KTQLEELEDELQATEDAKLR---LEVNMQALKGQFERDLQARD----EQNEEKRRQLQRQ 1597
Query: 68 --------ESARRENILVMRLATK-EQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAIN 118
E R++ L K E ++++ Q + ++ ++ QLR
Sbjct: 1598 LHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR--------- 1648
Query: 119 LFFLKMKGELEQTKDKLEQAQ---NELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQL 175
K++ +++ + +LE A+ +E+ A T K+ K + L + +L L
Sbjct: 1649 ----KLQAQMKDFQRELEDARASRDEIFA--------TAKENEKKAKSLEADLMQLQEDL 1696
Query: 176 SQGRIAQLEAELALQKKYSEELKSS-------QDE---LNDFIIQLDEEVEGMQSTILVL 225
+ A+ +A+L +++ +EEL SS QDE L I QL+EE+E Q + +
Sbjct: 1697 AAAERARKQADLE-KEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1755
Query: 226 QQQLKETRQQLAQYQQQQSQASAPSTSRTTASEPVEQ 262
++++ QQ Q + + + + +A + +E+
Sbjct: 1756 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 1792
Score = 48.1 bits (113), Expect = 1e-05
Identities = 66/347 (19%), Positives = 145/347 (41%), Gaps = 54/347 (15%)
Query: 15 ETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSND---VTGLRESEEKLK-------Q 64
+ D + R+E I + ++ +A ++ + + D ++ +E+E+K K Q
Sbjct: 1632 QADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQ 1691
Query: 65 QQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQ------QPSVAQLRSTMVDPAIN 118
Q++ A E KE+ +E + + +Q + +AQL + + N
Sbjct: 1692 LQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGN 1751
Query: 119 LFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQ- 177
+ M + + + EQ NEL+ + T +K + + L ++N+EL +L +
Sbjct: 1752 ME--AMSDRVRKATQQAEQLSNELAT-----ERSTAQKNESARQQLERQNKELRSKLHEM 1804
Query: 178 ----------------GRIAQLEAELALQKK----YSEELKSSQDELNDFIIQLDEE--- 214
+IAQLE ++ + + ++ LK +L + ++Q+++E
Sbjct: 1805 EGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKM 1864
Query: 215 VEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPSTS-RTTASEPVEQSEATSKDC--- 270
E + ++K+ ++QL + +++ + +A + E E +EA ++
Sbjct: 1865 AEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNAL 1924
Query: 271 -SRLTNGPSNGSSSRQRTSGSGF--HREGNTTEDDFPSSPGNGNKSS 314
S+L G +R+ G + +G+ E D + NG K+S
Sbjct: 1925 KSKLRRGNETSFVPSRRSGGRRVIENADGSEEETDTRDADFNGTKAS 1971
Score = 45.8 bits (107), Expect = 7e-05
Identities = 45/187 (24%), Positives = 86/187 (45%), Gaps = 10/187 (5%)
Query: 53 TGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTM 112
T L ++ + QQ+ A+RE + + ++E + Q+Q ++Q +V +L +
Sbjct: 1153 TELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQL 1212
Query: 113 VDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELG 172
F + K L++ K LE+ +L A + Q +++ K + L + QEL
Sbjct: 1213 EQ------FKRAKANLDKNKQTLEKENADL-AGELRVLGQAKQEVEHKKKKLEAQVQELQ 1265
Query: 173 RQLSQGRIAQLEAELALQKKYS--EELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQL- 229
+ S G A+ E + K + E + +E I+L ++V + S + Q+ L
Sbjct: 1266 SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ 1325
Query: 230 KETRQQL 236
+ETRQ+L
Sbjct: 1326 EETRQKL 1332
Score = 44.3 bits (103), Expect = 2e-04
Identities = 56/268 (20%), Positives = 121/268 (45%), Gaps = 47/268 (17%)
Query: 2 TNEEPLPKKVRLSETDFKVMARDELILRWKQY----EAYVQALEGKYTDLNSNDVTGLRE 57
T +PL + R E ++ A+++ + + K+ E ++ LE K++ L
Sbjct: 839 TKVKPLLQVTRQEE---EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEK----NL 891
Query: 58 SEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAI 117
+E+L+ + + A E + V RLA K+QE++E +++ + ++ QL++ A
Sbjct: 892 LQEQLQAETELYAEAEEMRV-RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQ 950
Query: 118 NLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGK-------------KLMAKCRML 164
+ +LE+ ++ E A+ +L K T +++ K KL + ++L
Sbjct: 951 QML------DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLL 1004
Query: 165 ----------IQENQELGRQLS------QGRIAQLEAELALQKKYSEELKSSQDELNDFI 208
+ E +E + L+ + I++LE L ++K +EL+ + +L
Sbjct: 1005 EERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDA 1064
Query: 209 IQLDEEVEGMQSTILVLQQQLKETRQQL 236
E++ +Q+ I L+ QL + ++L
Sbjct: 1065 SDFHEQIADLQAQIAELKMQLAKKEEEL 1092
Score = 43.1 bits (100), Expect = 4e-04
Identities = 50/220 (22%), Positives = 95/220 (43%), Gaps = 35/220 (15%)
Query: 31 KQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQ-- 88
+ +EA VQ + K+ V L E E+ K+ + + + L A E++
Sbjct: 1188 RSHEAQVQEMRQKHAQA----VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1243
Query: 89 -ECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKF 147
+ ++++ K+ + V +L+S D + + EL DK+ + QNE+ +
Sbjct: 1244 GQAKQEVEHKKKKLEAQVQELQSKCSDGE------RARAELN---DKVHKLQNEVESVTG 1294
Query: 148 TPDSQTGKKL-----MAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQD 202
+ GK + +A +Q+ QEL L+ E + S +L+ ++
Sbjct: 1295 MLNEAEGKAIKLAKDVASLSSQLQDTQEL-----------LQEETRQKLNVSTKLRQLEE 1343
Query: 203 ELNDFIIQLDEEVEGMQST---ILVLQQQLKETRQQLAQY 239
E N QLDEE+E Q+ I L QL +++++L +
Sbjct: 1344 ERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDF 1383
Score = 41.6 bits (96), Expect = 0.001
Identities = 48/238 (20%), Positives = 114/238 (47%), Gaps = 18/238 (7%)
Query: 35 AYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQI 94
A +ALE K +N + L+ E L + + + + L E +M+E TQ+
Sbjct: 1491 ALEEALEAKEELERTNKM--LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL 1548
Query: 95 QYLK-QVQQPSVAQLRSTMVDPAINLFFLK-MKGELEQTKDKLEQAQNELSAWKFTPDSQ 152
+ L+ ++Q A+LR + A+ F + ++ EQ ++K Q Q +L ++ + +
Sbjct: 1549 EELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDE 1608
Query: 153 TGKKLMA-----------KCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQ 201
++ +A K L ++ GR+ + ++ +L+A++ ++ E+ ++S+
Sbjct: 1609 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1668
Query: 202 DELNDFIIQLDEEVEGMQSTILVLQQQL---KETRQQLAQYQQQQSQASAPSTSRTTA 256
DE+ + +++ + +++ ++ LQ+ L + R+Q +++ ++ A S S A
Sbjct: 1669 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA 1726
Score = 33.9 bits (76), Expect = 0.26
Identities = 41/193 (21%), Positives = 84/193 (43%), Gaps = 27/193 (13%)
Query: 22 ARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLA 81
AR +L L EA ++ LE +++ + + KL ++++ R + L LA
Sbjct: 965 ARQKLQLEKVTAEAKIKKLE--------DEILVMDDQNNKLSKERKLLEERISDLTTNLA 1016
Query: 82 TKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNE 141
+E++ + T LK + +++L + K + ELE+ K KLE ++
Sbjct: 1017 EEEEKAKNLTK----LKNKHESMISELEVRLKKEE------KSRQELEKLKRKLEGDASD 1066
Query: 142 LSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQ 201
+Q + M L ++ +EL Q +A+L+ E+A + ++++ +
Sbjct: 1067 FHEQIADLQAQIAELKM----QLAKKEEEL-----QAALARLDDEIAQKNNALKKIRELE 1117
Query: 202 DELNDFIIQLDEE 214
++D LD E
Sbjct: 1118 GHISDLQEDLDSE 1130
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 50.8 bits (120), Expect = 2e-06
Identities = 64/277 (23%), Positives = 128/277 (46%), Gaps = 53/277 (19%)
Query: 10 KVRLSETDFKVMARDELILRWKQYEAYVQALEGKYT-DLNSNDVTGLRESEEKLKQQQQ- 67
K +L E + ++ A ++ LR E +QAL+G++ DL + D ++EEK +Q Q+
Sbjct: 1552 KTQLEELEDELQATEDAKLR---LEVNMQALKGQFERDLQARD----EQNEEKRRQLQRQ 1604
Query: 68 --------ESARRENILVMRLATK-EQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAIN 118
E R++ L K E ++++ Q + ++ ++ QLR
Sbjct: 1605 LHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR--------- 1655
Query: 119 LFFLKMKGELEQTKDKLEQAQ---NELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQL 175
K++ +++ + +LE A+ +E+ A T K+ K + L + +L L
Sbjct: 1656 ----KLQAQMKDFQRELEDARASRDEIFA--------TAKENEKKAKSLEADLMQLQEDL 1703
Query: 176 SQGRIAQLEAELALQKKYSEELKSS-------QDE---LNDFIIQLDEEVEGMQSTILVL 225
+ A+ +A+L +++ +EEL SS QDE L I QL+EE+E Q + +
Sbjct: 1704 AAAERARKQADLE-KEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1762
Query: 226 QQQLKETRQQLAQYQQQQSQASAPSTSRTTASEPVEQ 262
++++ QQ Q + + + + +A + +E+
Sbjct: 1763 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 1799
Score = 48.1 bits (113), Expect = 1e-05
Identities = 66/347 (19%), Positives = 145/347 (41%), Gaps = 54/347 (15%)
Query: 15 ETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSND---VTGLRESEEKLK-------Q 64
+ D + R+E I + ++ +A ++ + + D ++ +E+E+K K Q
Sbjct: 1639 QADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQ 1698
Query: 65 QQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQ------QPSVAQLRSTMVDPAIN 118
Q++ A E KE+ +E + + +Q + +AQL + + N
Sbjct: 1699 LQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGN 1758
Query: 119 LFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQ- 177
+ M + + + EQ NEL+ + T +K + + L ++N+EL +L +
Sbjct: 1759 ME--AMSDRVRKATQQAEQLSNELAT-----ERSTAQKNESARQQLERQNKELRSKLHEM 1811
Query: 178 ----------------GRIAQLEAELALQKK----YSEELKSSQDELNDFIIQLDEE--- 214
+IAQLE ++ + + ++ LK +L + ++Q+++E
Sbjct: 1812 EGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKM 1871
Query: 215 VEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPSTS-RTTASEPVEQSEATSKDC--- 270
E + ++K+ ++QL + +++ + +A + E E +EA ++
Sbjct: 1872 AEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNAL 1931
Query: 271 -SRLTNGPSNGSSSRQRTSGSGF--HREGNTTEDDFPSSPGNGNKSS 314
S+L G +R+ G + +G+ E D + NG K+S
Sbjct: 1932 KSKLRRGNETSFVPSRRSGGRRVIENADGSEEETDTRDADFNGTKAS 1978
Score = 45.8 bits (107), Expect = 7e-05
Identities = 45/187 (24%), Positives = 86/187 (45%), Gaps = 10/187 (5%)
Query: 53 TGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTM 112
T L ++ + QQ+ A+RE + + ++E + Q+Q ++Q +V +L +
Sbjct: 1160 TELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQL 1219
Query: 113 VDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELG 172
F + K L++ K LE+ +L A + Q +++ K + L + QEL
Sbjct: 1220 EQ------FKRAKANLDKNKQTLEKENADL-AGELRVLGQAKQEVEHKKKKLEAQVQELQ 1272
Query: 173 RQLSQGRIAQLEAELALQKKYS--EELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQL- 229
+ S G A+ E + K + E + +E I+L ++V + S + Q+ L
Sbjct: 1273 SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ 1332
Query: 230 KETRQQL 236
+ETRQ+L
Sbjct: 1333 EETRQKL 1339
Score = 44.3 bits (103), Expect = 2e-04
Identities = 56/268 (20%), Positives = 121/268 (45%), Gaps = 47/268 (17%)
Query: 2 TNEEPLPKKVRLSETDFKVMARDELILRWKQY----EAYVQALEGKYTDLNSNDVTGLRE 57
T +PL + R E ++ A+++ + + K+ E ++ LE K++ L
Sbjct: 846 TKVKPLLQVTRQEE---EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEK----NL 898
Query: 58 SEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAI 117
+E+L+ + + A E + V RLA K+QE++E +++ + ++ QL++ A
Sbjct: 899 LQEQLQAETELYAEAEEMRV-RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQ 957
Query: 118 NLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGK-------------KLMAKCRML 164
+ +LE+ ++ E A+ +L K T +++ K KL + ++L
Sbjct: 958 QML------DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLL 1011
Query: 165 ----------IQENQELGRQLS------QGRIAQLEAELALQKKYSEELKSSQDELNDFI 208
+ E +E + L+ + I++LE L ++K +EL+ + +L
Sbjct: 1012 EERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDA 1071
Query: 209 IQLDEEVEGMQSTILVLQQQLKETRQQL 236
E++ +Q+ I L+ QL + ++L
Sbjct: 1072 SDFHEQIADLQAQIAELKMQLAKKEEEL 1099
Score = 43.1 bits (100), Expect = 4e-04
Identities = 50/220 (22%), Positives = 95/220 (43%), Gaps = 35/220 (15%)
Query: 31 KQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQ-- 88
+ +EA VQ + K+ V L E E+ K+ + + + L A E++
Sbjct: 1195 RSHEAQVQEMRQKHAQA----VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1250
Query: 89 -ECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKF 147
+ ++++ K+ + V +L+S D + + EL DK+ + QNE+ +
Sbjct: 1251 GQAKQEVEHKKKKLEAQVQELQSKCSDGE------RARAELN---DKVHKLQNEVESVTG 1301
Query: 148 TPDSQTGKKL-----MAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQD 202
+ GK + +A +Q+ QEL L+ E + S +L+ ++
Sbjct: 1302 MLNEAEGKAIKLAKDVASLSSQLQDTQEL-----------LQEETRQKLNVSTKLRQLEE 1350
Query: 203 ELNDFIIQLDEEVEGMQST---ILVLQQQLKETRQQLAQY 239
E N QLDEE+E Q+ I L QL +++++L +
Sbjct: 1351 ERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDF 1390
Score = 41.6 bits (96), Expect = 0.001
Identities = 48/238 (20%), Positives = 114/238 (47%), Gaps = 18/238 (7%)
Query: 35 AYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQI 94
A +ALE K +N + L+ E L + + + + L E +M+E TQ+
Sbjct: 1498 ALEEALEAKEELERTNKM--LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL 1555
Query: 95 QYLK-QVQQPSVAQLRSTMVDPAINLFFLK-MKGELEQTKDKLEQAQNELSAWKFTPDSQ 152
+ L+ ++Q A+LR + A+ F + ++ EQ ++K Q Q +L ++ + +
Sbjct: 1556 EELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDE 1615
Query: 153 TGKKLMA-----------KCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQ 201
++ +A K L ++ GR+ + ++ +L+A++ ++ E+ ++S+
Sbjct: 1616 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1675
Query: 202 DELNDFIIQLDEEVEGMQSTILVLQQQL---KETRQQLAQYQQQQSQASAPSTSRTTA 256
DE+ + +++ + +++ ++ LQ+ L + R+Q +++ ++ A S S A
Sbjct: 1676 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA 1733
Score = 33.9 bits (76), Expect = 0.26
Identities = 41/193 (21%), Positives = 84/193 (43%), Gaps = 27/193 (13%)
Query: 22 ARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLA 81
AR +L L EA ++ LE +++ + + KL ++++ R + L LA
Sbjct: 972 ARQKLQLEKVTAEAKIKKLE--------DEILVMDDQNNKLSKERKLLEERISDLTTNLA 1023
Query: 82 TKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNE 141
+E++ + T LK + +++L + K + ELE+ K KLE ++
Sbjct: 1024 EEEEKAKNLTK----LKNKHESMISELEVRLKKEE------KSRQELEKLKRKLEGDASD 1073
Query: 142 LSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQ 201
+Q + M L ++ +EL Q +A+L+ E+A + ++++ +
Sbjct: 1074 FHEQIADLQAQIAELKM----QLAKKEEEL-----QAALARLDDEIAQKNNALKKIRELE 1124
Query: 202 DELNDFIIQLDEE 214
++D LD E
Sbjct: 1125 GHISDLQEDLDSE 1137
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 50.8 bits (120), Expect = 2e-06
Identities = 64/277 (23%), Positives = 128/277 (46%), Gaps = 53/277 (19%)
Query: 10 KVRLSETDFKVMARDELILRWKQYEAYVQALEGKYT-DLNSNDVTGLRESEEKLKQQQQ- 67
K +L E + ++ A ++ LR E +QAL+G++ DL + D ++EEK +Q Q+
Sbjct: 1552 KTQLEELEDELQATEDAKLR---LEVNMQALKGQFERDLQARD----EQNEEKRRQLQRQ 1604
Query: 68 --------ESARRENILVMRLATK-EQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAIN 118
E R++ L K E ++++ Q + ++ ++ QLR
Sbjct: 1605 LHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR--------- 1655
Query: 119 LFFLKMKGELEQTKDKLEQAQ---NELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQL 175
K++ +++ + +LE A+ +E+ A T K+ K + L + +L L
Sbjct: 1656 ----KLQAQMKDFQRELEDARASRDEIFA--------TAKENEKKAKSLEADLMQLQEDL 1703
Query: 176 SQGRIAQLEAELALQKKYSEELKSS-------QDE---LNDFIIQLDEEVEGMQSTILVL 225
+ A+ +A+L +++ +EEL SS QDE L I QL+EE+E Q + +
Sbjct: 1704 AAAERARKQADLE-KEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1762
Query: 226 QQQLKETRQQLAQYQQQQSQASAPSTSRTTASEPVEQ 262
++++ QQ Q + + + + +A + +E+
Sbjct: 1763 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 1799
Score = 45.8 bits (107), Expect = 7e-05
Identities = 45/187 (24%), Positives = 86/187 (45%), Gaps = 10/187 (5%)
Query: 53 TGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTM 112
T L ++ + QQ+ A+RE + + ++E + Q+Q ++Q +V +L +
Sbjct: 1160 TELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQL 1219
Query: 113 VDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELG 172
F + K L++ K LE+ +L A + Q +++ K + L + QEL
Sbjct: 1220 EQ------FKRAKANLDKNKQTLEKENADL-AGELRVLGQAKQEVEHKKKKLEAQVQELQ 1272
Query: 173 RQLSQGRIAQLEAELALQKKYS--EELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQL- 229
+ S G A+ E + K + E + +E I+L ++V + S + Q+ L
Sbjct: 1273 SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ 1332
Query: 230 KETRQQL 236
+ETRQ+L
Sbjct: 1333 EETRQKL 1339
Score = 44.3 bits (103), Expect = 2e-04
Identities = 56/268 (20%), Positives = 121/268 (45%), Gaps = 47/268 (17%)
Query: 2 TNEEPLPKKVRLSETDFKVMARDELILRWKQY----EAYVQALEGKYTDLNSNDVTGLRE 57
T +PL + R E ++ A+++ + + K+ E ++ LE K++ L
Sbjct: 846 TKVKPLLQVTRQEE---EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEK----NL 898
Query: 58 SEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAI 117
+E+L+ + + A E + V RLA K+QE++E +++ + ++ QL++ A
Sbjct: 899 LQEQLQAETELYAEAEEMRV-RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQ 957
Query: 118 NLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGK-------------KLMAKCRML 164
+ +LE+ ++ E A+ +L K T +++ K KL + ++L
Sbjct: 958 QML------DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLL 1011
Query: 165 ----------IQENQELGRQLS------QGRIAQLEAELALQKKYSEELKSSQDELNDFI 208
+ E +E + L+ + I++LE L ++K +EL+ + +L
Sbjct: 1012 EERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDA 1071
Query: 209 IQLDEEVEGMQSTILVLQQQLKETRQQL 236
E++ +Q+ I L+ QL + ++L
Sbjct: 1072 SDFHEQIADLQAQIAELKMQLAKKEEEL 1099
Score = 43.1 bits (100), Expect = 4e-04
Identities = 50/220 (22%), Positives = 95/220 (43%), Gaps = 35/220 (15%)
Query: 31 KQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQ-- 88
+ +EA VQ + K+ V L E E+ K+ + + + L A E++
Sbjct: 1195 RSHEAQVQEMRQKHAQA----VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1250
Query: 89 -ECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKF 147
+ ++++ K+ + V +L+S D + + EL DK+ + QNE+ +
Sbjct: 1251 GQAKQEVEHKKKKLEAQVQELQSKCSDGE------RARAELN---DKVHKLQNEVESVTG 1301
Query: 148 TPDSQTGKKL-----MAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQD 202
+ GK + +A +Q+ QEL L+ E + S +L+ ++
Sbjct: 1302 MLNEAEGKAIKLAKDVASLSSQLQDTQEL-----------LQEETRQKLNVSTKLRQLEE 1350
Query: 203 ELNDFIIQLDEEVEGMQST---ILVLQQQLKETRQQLAQY 239
E N QLDEE+E Q+ I L QL +++++L +
Sbjct: 1351 ERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDF 1390
Score = 42.0 bits (97), Expect = 0.001
Identities = 55/300 (18%), Positives = 127/300 (42%), Gaps = 48/300 (16%)
Query: 15 ETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSND---VTGLRESEEKLK-------Q 64
+ D + R+E I + ++ +A ++ + + D ++ +E+E+K K Q
Sbjct: 1639 QADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQ 1698
Query: 65 QQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQ------QPSVAQLRSTMVDPAIN 118
Q++ A E KE+ +E + + +Q + +AQL + + N
Sbjct: 1699 LQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGN 1758
Query: 119 LFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQ- 177
+ M + + + EQ NEL+ + T +K + + L ++N+EL +L +
Sbjct: 1759 ME--AMSDRVRKATQQAEQLSNELAT-----ERSTAQKNESARQQLERQNKELRSKLHEM 1811
Query: 178 ----------------GRIAQLEAELALQKK----YSEELKSSQDELNDFIIQLDEE--- 214
+IAQLE ++ + + ++ LK +L + ++Q+++E
Sbjct: 1812 EGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKM 1871
Query: 215 VEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPSTS-RTTASEPVEQSEATSKDCSRL 273
E + ++K+ ++QL + +++ + +A + E E +EA ++ + L
Sbjct: 1872 AEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNAL 1931
Score = 41.6 bits (96), Expect = 0.001
Identities = 48/238 (20%), Positives = 114/238 (47%), Gaps = 18/238 (7%)
Query: 35 AYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQI 94
A +ALE K +N + L+ E L + + + + L E +M+E TQ+
Sbjct: 1498 ALEEALEAKEELERTNKM--LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL 1555
Query: 95 QYLK-QVQQPSVAQLRSTMVDPAINLFFLK-MKGELEQTKDKLEQAQNELSAWKFTPDSQ 152
+ L+ ++Q A+LR + A+ F + ++ EQ ++K Q Q +L ++ + +
Sbjct: 1556 EELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDE 1615
Query: 153 TGKKLMA-----------KCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQ 201
++ +A K L ++ GR+ + ++ +L+A++ ++ E+ ++S+
Sbjct: 1616 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1675
Query: 202 DELNDFIIQLDEEVEGMQSTILVLQQQL---KETRQQLAQYQQQQSQASAPSTSRTTA 256
DE+ + +++ + +++ ++ LQ+ L + R+Q +++ ++ A S S A
Sbjct: 1676 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA 1733
Score = 33.9 bits (76), Expect = 0.26
Identities = 41/193 (21%), Positives = 84/193 (43%), Gaps = 27/193 (13%)
Query: 22 ARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLA 81
AR +L L EA ++ LE +++ + + KL ++++ R + L LA
Sbjct: 972 ARQKLQLEKVTAEAKIKKLE--------DEILVMDDQNNKLSKERKLLEERISDLTTNLA 1023
Query: 82 TKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNE 141
+E++ + T LK + +++L + K + ELE+ K KLE ++
Sbjct: 1024 EEEEKAKNLTK----LKNKHESMISELEVRLKKEE------KSRQELEKLKRKLEGDASD 1073
Query: 142 LSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQ 201
+Q + M L ++ +EL Q +A+L+ E+A + ++++ +
Sbjct: 1074 FHEQIADLQAQIAELKM----QLAKKEEEL-----QAALARLDDEIAQKNNALKKIRELE 1124
Query: 202 DELNDFIIQLDEE 214
++D LD E
Sbjct: 1125 GHISDLQEDLDSE 1137
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 50.8 bits (120), Expect = 2e-06
Identities = 64/277 (23%), Positives = 128/277 (46%), Gaps = 53/277 (19%)
Query: 10 KVRLSETDFKVMARDELILRWKQYEAYVQALEGKYT-DLNSNDVTGLRESEEKLKQQQQ- 67
K +L E + ++ A ++ LR E +QAL+G++ DL + D ++EEK +Q Q+
Sbjct: 1545 KTQLEELEDELQATEDAKLR---LEVNMQALKGQFERDLQARD----EQNEEKRRQLQRQ 1597
Query: 68 --------ESARRENILVMRLATK-EQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAIN 118
E R++ L K E ++++ Q + ++ ++ QLR
Sbjct: 1598 LHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR--------- 1648
Query: 119 LFFLKMKGELEQTKDKLEQAQ---NELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQL 175
K++ +++ + +LE A+ +E+ A T K+ K + L + +L L
Sbjct: 1649 ----KLQAQMKDFQRELEDARASRDEIFA--------TAKENEKKAKSLEADLMQLQEDL 1696
Query: 176 SQGRIAQLEAELALQKKYSEELKSS-------QDE---LNDFIIQLDEEVEGMQSTILVL 225
+ A+ +A+L +++ +EEL SS QDE L I QL+EE+E Q + +
Sbjct: 1697 AAAERARKQADLE-KEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1755
Query: 226 QQQLKETRQQLAQYQQQQSQASAPSTSRTTASEPVEQ 262
++++ QQ Q + + + + +A + +E+
Sbjct: 1756 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 1792
Score = 45.8 bits (107), Expect = 7e-05
Identities = 45/187 (24%), Positives = 86/187 (45%), Gaps = 10/187 (5%)
Query: 53 TGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTM 112
T L ++ + QQ+ A+RE + + ++E + Q+Q ++Q +V +L +
Sbjct: 1153 TELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQL 1212
Query: 113 VDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELG 172
F + K L++ K LE+ +L A + Q +++ K + L + QEL
Sbjct: 1213 EQ------FKRAKANLDKNKQTLEKENADL-AGELRVLGQAKQEVEHKKKKLEAQVQELQ 1265
Query: 173 RQLSQGRIAQLEAELALQKKYS--EELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQL- 229
+ S G A+ E + K + E + +E I+L ++V + S + Q+ L
Sbjct: 1266 SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ 1325
Query: 230 KETRQQL 236
+ETRQ+L
Sbjct: 1326 EETRQKL 1332
Score = 44.3 bits (103), Expect = 2e-04
Identities = 56/268 (20%), Positives = 121/268 (45%), Gaps = 47/268 (17%)
Query: 2 TNEEPLPKKVRLSETDFKVMARDELILRWKQY----EAYVQALEGKYTDLNSNDVTGLRE 57
T +PL + R E ++ A+++ + + K+ E ++ LE K++ L
Sbjct: 839 TKVKPLLQVTRQEE---EMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEK----NL 891
Query: 58 SEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAI 117
+E+L+ + + A E + V RLA K+QE++E +++ + ++ QL++ A
Sbjct: 892 LQEQLQAETELYAEAEEMRV-RLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQ 950
Query: 118 NLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGK-------------KLMAKCRML 164
+ +LE+ ++ E A+ +L K T +++ K KL + ++L
Sbjct: 951 QML------DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLL 1004
Query: 165 ----------IQENQELGRQLS------QGRIAQLEAELALQKKYSEELKSSQDELNDFI 208
+ E +E + L+ + I++LE L ++K +EL+ + +L
Sbjct: 1005 EERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDA 1064
Query: 209 IQLDEEVEGMQSTILVLQQQLKETRQQL 236
E++ +Q+ I L+ QL + ++L
Sbjct: 1065 SDFHEQIADLQAQIAELKMQLAKKEEEL 1092
Score = 43.1 bits (100), Expect = 4e-04
Identities = 50/220 (22%), Positives = 95/220 (43%), Gaps = 35/220 (15%)
Query: 31 KQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQ-- 88
+ +EA VQ + K+ V L E E+ K+ + + + L A E++
Sbjct: 1188 RSHEAQVQEMRQKHAQA----VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1243
Query: 89 -ECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKF 147
+ ++++ K+ + V +L+S D + + EL DK+ + QNE+ +
Sbjct: 1244 GQAKQEVEHKKKKLEAQVQELQSKCSDGE------RARAELN---DKVHKLQNEVESVTG 1294
Query: 148 TPDSQTGKKL-----MAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQD 202
+ GK + +A +Q+ QEL L+ E + S +L+ ++
Sbjct: 1295 MLNEAEGKAIKLAKDVASLSSQLQDTQEL-----------LQEETRQKLNVSTKLRQLEE 1343
Query: 203 ELNDFIIQLDEEVEGMQST---ILVLQQQLKETRQQLAQY 239
E N QLDEE+E Q+ I L QL +++++L +
Sbjct: 1344 ERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDF 1383
Score = 42.0 bits (97), Expect = 0.001
Identities = 55/300 (18%), Positives = 127/300 (42%), Gaps = 48/300 (16%)
Query: 15 ETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSND---VTGLRESEEKLK-------Q 64
+ D + R+E I + ++ +A ++ + + D ++ +E+E+K K Q
Sbjct: 1632 QADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQ 1691
Query: 65 QQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQ------QPSVAQLRSTMVDPAIN 118
Q++ A E KE+ +E + + +Q + +AQL + + N
Sbjct: 1692 LQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGN 1751
Query: 119 LFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQ- 177
+ M + + + EQ NEL+ + T +K + + L ++N+EL +L +
Sbjct: 1752 ME--AMSDRVRKATQQAEQLSNELAT-----ERSTAQKNESARQQLERQNKELRSKLHEM 1804
Query: 178 ----------------GRIAQLEAELALQKK----YSEELKSSQDELNDFIIQLDEE--- 214
+IAQLE ++ + + ++ LK +L + ++Q+++E
Sbjct: 1805 EGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKM 1864
Query: 215 VEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPSTS-RTTASEPVEQSEATSKDCSRL 273
E + ++K+ ++QL + +++ + +A + E E +EA ++ + L
Sbjct: 1865 AEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNAL 1924
Score = 41.6 bits (96), Expect = 0.001
Identities = 48/238 (20%), Positives = 114/238 (47%), Gaps = 18/238 (7%)
Query: 35 AYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQI 94
A +ALE K +N + L+ E L + + + + L E +M+E TQ+
Sbjct: 1491 ALEEALEAKEELERTNKM--LKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL 1548
Query: 95 QYLK-QVQQPSVAQLRSTMVDPAINLFFLK-MKGELEQTKDKLEQAQNELSAWKFTPDSQ 152
+ L+ ++Q A+LR + A+ F + ++ EQ ++K Q Q +L ++ + +
Sbjct: 1549 EELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDE 1608
Query: 153 TGKKLMA-----------KCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQ 201
++ +A K L ++ GR+ + ++ +L+A++ ++ E+ ++S+
Sbjct: 1609 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1668
Query: 202 DELNDFIIQLDEEVEGMQSTILVLQQQL---KETRQQLAQYQQQQSQASAPSTSRTTA 256
DE+ + +++ + +++ ++ LQ+ L + R+Q +++ ++ A S S A
Sbjct: 1669 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNA 1726
Score = 33.9 bits (76), Expect = 0.26
Identities = 41/193 (21%), Positives = 84/193 (43%), Gaps = 27/193 (13%)
Query: 22 ARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLA 81
AR +L L EA ++ LE +++ + + KL ++++ R + L LA
Sbjct: 965 ARQKLQLEKVTAEAKIKKLE--------DEILVMDDQNNKLSKERKLLEERISDLTTNLA 1016
Query: 82 TKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNE 141
+E++ + T LK + +++L + K + ELE+ K KLE ++
Sbjct: 1017 EEEEKAKNLTK----LKNKHESMISELEVRLKKEE------KSRQELEKLKRKLEGDASD 1066
Query: 142 LSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQ 201
+Q + M L ++ +EL Q +A+L+ E+A + ++++ +
Sbjct: 1067 FHEQIADLQAQIAELKM----QLAKKEEEL-----QAALARLDDEIAQKNNALKKIRELE 1117
Query: 202 DELNDFIIQLDEE 214
++D LD E
Sbjct: 1118 GHISDLQEDLDSE 1130
>gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens]
Length = 1505
Score = 50.4 bits (119), Expect = 3e-06
Identities = 75/366 (20%), Positives = 147/366 (40%), Gaps = 46/366 (12%)
Query: 5 EPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVT------GLRES 58
+P+P + KV ++ ++ ++ ++ ++ + +VT +RE
Sbjct: 90 DPVPALDLGQQLQLKVQRLHDIETENQKLRETLEEYNKEFAEVKNQEVTIKALKEKIREY 149
Query: 59 EEKLKQQQQESA-RRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAI 117
E+ LK Q + A +E L A KE+++QE + + V L++ +
Sbjct: 150 EQTLKNQAETIALEKEQKLQNDFAEKERKLQETQMSTTSKLEEAEHKVQSLQTALEKTRT 209
Query: 118 NLFFLKMK----------------GELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMA-- 159
LF LK K +LE+ + E AQ E + S +A
Sbjct: 210 ELFDLKTKYDEETTAKADEIEMIMTDLERANQRAEVAQREAETLREQLSSANHSLQLASQ 269
Query: 160 --KCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELND----FIIQLDE 213
K + Q + L R + +A E E+A + + L++S +L + I QL++
Sbjct: 270 IQKAPDVEQAIEVLTRSSLEVELAAKEREIAQLVEDVQRLQASLTKLRENSASQISQLEQ 329
Query: 214 EVEGMQSTILVLQQQLK---ETRQQLAQYQQQQSQASAPSTSRTT--ASEPVE------- 261
++ ST+ L+++LK + + + +S APS T A++P+E
Sbjct: 330 QLSAKNSTLKQLEEKLKGQADYEEVKKELNILKSMEFAPSEGAGTQDAAKPLEVLLLEKN 389
Query: 262 QSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGN---TTEDDFPSSPGNGNKSSNSSE 318
+S + R++N +GS+ R+ R G+ P +PG ++N +
Sbjct: 390 RSLQSENAALRISNSDLSGSARRKGKDQPESRRPGSLPAPPPSQLPRNPGEQASNTNGTH 449
Query: 319 ERTGRG 324
+ + G
Sbjct: 450 QFSPAG 455
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 49.7 bits (117), Expect = 5e-06
Identities = 41/154 (26%), Positives = 73/154 (47%), Gaps = 11/154 (7%)
Query: 244 SQASAPSTSRTTASEPVEQSEAT-SKDCSRLTNGP-SNGSSSRQRTSGSGFHREGNTTED 301
S S+ S+ + +S+ + S+++ S D S +N S+ SS +S S + + + D
Sbjct: 1147 SSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD 1206
Query: 302 DFPSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSND-TDSSH 360
SS + + S+ S + + S + S +S DS S++S + S+D T S+
Sbjct: 1207 SSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSN 1266
Query: 361 DPQEEKAVSGKGNRTVGSRHVQNGLDSSVNVQGS 394
D + ++ SG GN NG DS + +GS
Sbjct: 1267 DESDSQSKSGNGN--------NNGSDSDSDSEGS 1292
Score = 46.2 bits (108), Expect = 5e-05
Identities = 39/148 (26%), Positives = 67/148 (45%), Gaps = 4/148 (2%)
Query: 244 SQASAPSTSRTTASEPVEQSEAT-SKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTEDD 302
S S+ S+ + +S+ + S+++ SK S + S+ S S+ +S S + ++
Sbjct: 598 SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSS 657
Query: 303 FPSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSNDTDS--SH 360
S+ N + SS+SS+ S N S +S DS SE+S + S+D+DS S
Sbjct: 658 DSSNSSNSSDSSDSSDSSDSSSSSDSSNS-SDSSDSSDSSNSSESSDSSDSSDSDSSDSS 716
Query: 361 DPQEEKAVSGKGNRTVGSRHVQNGLDSS 388
D + + + S N DSS
Sbjct: 717 DSSNSNSSDSDSSNSSDSSDSSNSSDSS 744
Score = 45.1 bits (105), Expect = 1e-04
Identities = 40/163 (24%), Positives = 72/163 (44%), Gaps = 12/163 (7%)
Query: 244 SQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREG------- 296
S S+ S++ + +S+ + S++ S D S +N S+ S S + S
Sbjct: 689 SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSD 748
Query: 297 --NTTEDDFPSSPGNGNKSSNSSE--ERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQ 352
N+++ S N + SS+SS+ + + S N S +S DS S++S +
Sbjct: 749 SSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808
Query: 353 SND-TDSSHDPQEEKAVSGKGNRTVGSRHVQNGLDSSVNVQGS 394
S+D +DSS + S + + S + + DSS + GS
Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS 851
Score = 43.9 bits (102), Expect = 3e-04
Identities = 33/146 (22%), Positives = 62/146 (42%), Gaps = 5/146 (3%)
Query: 244 SQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTEDDF 303
S S+ S+ + +SE + S+++ D S ++ ++ SS ++ S N+++
Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSD 745
Query: 304 PSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSE-NSLTHQSNDTDSSHDP 362
S N + SS+SS+ S S +S DS S+ N ++ S+ +DSS+
Sbjct: 746 SSDSSNSSDSSDSSDSSNSSDSS----DSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSS 801
Query: 363 QEEKAVSGKGNRTVGSRHVQNGLDSS 388
+ + N DSS
Sbjct: 802 DSSNSSDSSDSSDSSDSDSSNSSDSS 827
Score = 43.5 bits (101), Expect = 3e-04
Identities = 36/148 (24%), Positives = 66/148 (44%), Gaps = 4/148 (2%)
Query: 244 SQASAPSTSRTTASEPVEQSEATSKDC-SRLTNGPSNGSSSRQRTSGSGFHREGNTTE-- 300
S S+ S+ + + +SE+ S D S+ + SN S S + S N+++
Sbjct: 610 SSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSS 669
Query: 301 DDFPSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSNDTDSSH 360
D SS + + S++S + + S ++ S +S DS + S++S + SN +DS
Sbjct: 670 DSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDS-SDSSDSSNSNSSDSDS 728
Query: 361 DPQEEKAVSGKGNRTVGSRHVQNGLDSS 388
+ + S + + S N DSS
Sbjct: 729 SNSSDSSDSSNSSDSSDSSDSSNSSDSS 756
Score = 43.5 bits (101), Expect = 3e-04
Identities = 38/147 (25%), Positives = 65/147 (44%), Gaps = 3/147 (2%)
Query: 244 SQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTEDDF 303
S +S S S ++ + + S D S ++G + SS+R +S S + + + +
Sbjct: 818 SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSS 877
Query: 304 PSSPGN-GNKSSNSSEERTGRGGS-GYVNQLSAGYESVDSPTGSENSLTHQSNDTDSSHD 361
SS + N+SSNSS+ S + S +S DS S++S + S+D +S D
Sbjct: 878 DSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD 937
Query: 362 PQEEKAVSGKGNRTVGSRHVQNGLDSS 388
+ S + + S N DSS
Sbjct: 938 -SSNSSDSSDSSDSSNSSDSSNSSDSS 963
Score = 42.7 bits (99), Expect = 6e-04
Identities = 39/151 (25%), Positives = 62/151 (41%), Gaps = 8/151 (5%)
Query: 244 SQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTEDDF 303
S S+ S+ + +S+ S+ S D S ++ S+ SS +S S + + D
Sbjct: 788 SSNSSDSSDSSNSSDSSNSSD--SSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845
Query: 304 PSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSNDTDSSHDPQ 363
SS G+ + SSN S+ S S S DS S+++ SN +DSS
Sbjct: 846 DSSDGSDSDSSNRSDSSNSSDSS----DSSDSSNSSDSSDSSDSN--ESSNSSDSSDSSN 899
Query: 364 EEKAVSGKGNRTVGSRHVQNGLDSSVNVQGS 394
+ S + + S N DSS + S
Sbjct: 900 SSDSDSSDSSNSSDSSDSSNSSDSSESSNSS 930
Score = 42.7 bits (99), Expect = 6e-04
Identities = 37/149 (24%), Positives = 67/149 (44%), Gaps = 7/149 (4%)
Query: 244 SQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTEDDF 303
S S+ S+ + +S+ + S+++ D S ++ S+ SS +S S + + + D
Sbjct: 794 SSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSD--SSNSSDSSDSSNSSDSSDSSDSSDGS 851
Query: 304 PSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSNDTDSS---- 359
S N + SSNSS+ S + S +S +S S++S + S+D+DSS
Sbjct: 852 DSDSSNRSDSSNSSDSSDSSDSSNSSDS-SDSSDSNESSNSSDSSDSSNSSDSDSSDSSN 910
Query: 360 HDPQEEKAVSGKGNRTVGSRHVQNGLDSS 388
+ + S + + S N DSS
Sbjct: 911 SSDSSDSSNSSDSSESSNSSDNSNSSDSS 939
Score = 41.2 bits (95), Expect = 0.002
Identities = 34/146 (23%), Positives = 62/146 (42%), Gaps = 3/146 (2%)
Query: 244 SQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTEDDF 303
S S+ S+ + +S+ + S++++ S ++ SN S S + S N+++ +
Sbjct: 728 SSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSND 787
Query: 304 PSSPGNGNKSSNSSEERTGRGGSGYVNQL-SAGYESVDSPTGSENSLTHQSNDTDSSHDP 362
S+ + + SSNSS+ S + S S DS S++S SN +DSS
Sbjct: 788 SSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS--DSSNSSDSSDSS 845
Query: 363 QEEKAVSGKGNRTVGSRHVQNGLDSS 388
+ S + + DSS
Sbjct: 846 DSSDGSDSDSSNRSDSSNSSDSSDSS 871
Score = 40.8 bits (94), Expect = 0.002
Identities = 31/145 (21%), Positives = 59/145 (40%), Gaps = 1/145 (0%)
Query: 244 SQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTEDDF 303
S +++ + + +S+ + S ++ S ++ S+ S S ++ S ++++
Sbjct: 719 SNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSD 778
Query: 304 PSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSNDTDSSHDPQ 363
S+ + N SSNSS+ S N + S S + S NS + SN +DSS
Sbjct: 779 SSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS-SDSSNSSDSSDSSN 837
Query: 364 EEKAVSGKGNRTVGSRHVQNGLDSS 388
+ + N DSS
Sbjct: 838 SSDSSDSSDSSDGSDSDSSNRSDSS 862
Score = 40.4 bits (93), Expect = 0.003
Identities = 30/149 (20%), Positives = 60/149 (40%), Gaps = 4/149 (2%)
Query: 244 SQASAPSTSRTTASEPVEQSEATSKDCSRLTNGP----SNGSSSRQRTSGSGFHREGNTT 299
S S+ S++ + +S+ + S+ + D S ++ S+ SS +S S + N +
Sbjct: 829 SSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNES 888
Query: 300 EDDFPSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSNDTDSS 359
+ SS + + S+SS+ S N + S S + + ++ S+ +DSS
Sbjct: 889 SNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSS 948
Query: 360 HDPQEEKAVSGKGNRTVGSRHVQNGLDSS 388
+ + + N DSS
Sbjct: 949 DSSNSSDSSNSSDSSNSSDSSDSNSSDSS 977
Score = 40.4 bits (93), Expect = 0.003
Identities = 31/145 (21%), Positives = 63/145 (43%), Gaps = 5/145 (3%)
Query: 246 ASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTEDDFPS 305
+ + S++R+ +S + S+++ S + S+ S S + ++ S N+++ D
Sbjct: 851 SDSDSSNRSDSSNSSDSSDSSDSSNS---SDSSDSSDSNESSNSSDSSDSSNSSDSDSSD 907
Query: 306 SPGNGNKS--SNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSNDTDSSHDPQ 363
S + + S SNSS+ S N + S S + ++ + SN +DSS+
Sbjct: 908 SSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSD 967
Query: 364 EEKAVSGKGNRTVGSRHVQNGLDSS 388
+ S + + S + DSS
Sbjct: 968 SSDSNSSDSSDSSNSSDSSDSSDSS 992
Score = 40.0 bits (92), Expect = 0.004
Identities = 33/148 (22%), Positives = 60/148 (40%), Gaps = 3/148 (2%)
Query: 244 SQASAPSTSRTTASEPVEQSEATSKDCSRLTNGP--SNGSSSRQRTSGSGFHREGNTTED 301
S +++ S S ++ S+ + S++ S D S ++ S+ S S + S + + +E
Sbjct: 572 SDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631
Query: 302 DFPSSPGNGNKS-SNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSNDTDSSH 360
D S + S SNSS+ S N ++ S S + +S + SN +DSS
Sbjct: 632 DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691
Query: 361 DPQEEKAVSGKGNRTVGSRHVQNGLDSS 388
+ + + DSS
Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSS 719
Score = 40.0 bits (92), Expect = 0.004
Identities = 36/147 (24%), Positives = 63/147 (42%), Gaps = 7/147 (4%)
Query: 243 QSQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTEDD 302
+S +S S S ++ + S D + +N S+ SS +S S N+++
Sbjct: 858 RSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSN--SSDSSDSSNSSDSDSSDSSNSSDSS 915
Query: 303 FPSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENS-LTHQSNDTDSSHD 361
S+ + ++SSNSS+ S S +S DS S++S + SN +DSS
Sbjct: 916 DSSNSSDSSESSNSSDNSNSSDSS----NSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS 971
Query: 362 PQEEKAVSGKGNRTVGSRHVQNGLDSS 388
+ + S + + S + DSS
Sbjct: 972 NSSDSSDSSNSSDSSDSSDSSDSSDSS 998
Score = 39.3 bits (90), Expect = 0.006
Identities = 36/160 (22%), Positives = 68/160 (42%), Gaps = 20/160 (12%)
Query: 244 SQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTEDDF 303
S S+ S++ + +S+ + S+++ S +N SN S S ++ S + + + D
Sbjct: 755 SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSS----DSSNSSDSS 810
Query: 304 PSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQS---------- 353
SS + + SSNSS+ S N S +S DS GS++ +++S
Sbjct: 811 DSSDSSDSDSSNSSDSSNSSDSSDSSNS-SDSSDSSDSSDGSDSDSSNRSDSSNSSDSSD 869
Query: 354 -----NDTDSSHDPQEEKAVSGKGNRTVGSRHVQNGLDSS 388
N +DSS ++ + + + + DSS
Sbjct: 870 SSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSS 909
Score = 38.9 bits (89), Expect = 0.008
Identities = 37/166 (22%), Positives = 74/166 (44%), Gaps = 19/166 (11%)
Query: 239 YQQQQSQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREG-- 296
+ + Q P++S + SE+ + SR G ++ +S + +G+G +G
Sbjct: 455 FDDKSMQGDDPNSSDESNGNDDANSESDNNSSSR---GDASYNSDESKDNGNGSDSKGAE 511
Query: 297 -----NTTEDDFPSSPGNGNKSSNSSEER-TGRGGSGYVNQLSA-------GYESVDSPT 343
+T++ + S GNGN ++ +++ +G+G S + S+ +S DS +
Sbjct: 512 DDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDS 571
Query: 344 GSENSLTHQ-SNDTDSSHDPQEEKAVSGKGNRTVGSRHVQNGLDSS 388
NS + S+D+DSS + + S + + S + DSS
Sbjct: 572 SDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSS 617
Score = 38.1 bits (87), Expect = 0.014
Identities = 31/145 (21%), Positives = 63/145 (43%), Gaps = 7/145 (4%)
Query: 244 SQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTEDDF 303
S S+ S+ + +S+ + SE++ S ++ S+ S S + S ++++
Sbjct: 1129 SSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1188
Query: 304 PSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSNDTDSSHDPQ 363
S + + SS+SS+ S + S +S DS S++S + SN++ S D
Sbjct: 1189 SSDSSDSSDSSDSSD-------SSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSS 1241
Query: 364 EEKAVSGKGNRTVGSRHVQNGLDSS 388
+ S + + S + DS+
Sbjct: 1242 DSSDSSNSSDSSDSSDSSDSTSDSN 1266
Score = 37.7 bits (86), Expect = 0.018
Identities = 34/129 (26%), Positives = 57/129 (44%), Gaps = 7/129 (5%)
Query: 262 QSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTE-DDFPSSPGNGNKSSNSSEER 320
+S+++ D S +N + SS +S S + ++++ D SS + + SSNSS+
Sbjct: 546 KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSS 605
Query: 321 TGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSNDTDSSHDPQEEKAVSGKGNR-TVGSR 379
S S +S DS + S S S+D+DS D + + N + S
Sbjct: 606 DSSDSS----DSSDSSDSSDSKSDSSKS-ESDSSDSDSKSDSSDSNSSDSSDNSDSSDSS 660
Query: 380 HVQNGLDSS 388
+ N DSS
Sbjct: 661 NSSNSSDSS 669
Score = 37.4 bits (85), Expect = 0.024
Identities = 34/143 (23%), Positives = 61/143 (42%), Gaps = 13/143 (9%)
Query: 237 AQYQQQQSQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREG 296
A Y +S+ + + A + + S++TS + +NG N + S SG +
Sbjct: 491 ASYNSDESKDNGNGSDSKGAED--DDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSD 548
Query: 297 NTTED--------DFPSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENS 348
++ D D S + + SNSS + S + S+ +S DS S++S
Sbjct: 549 SSDSDSSDSSNSSDSSDSSDSDSSDSNSSSD---SDSSDSDSSDSSDSDSSDSSNSSDSS 605
Query: 349 LTHQSNDTDSSHDPQEEKAVSGK 371
+ S+D+ S D + K+ S K
Sbjct: 606 DSSDSSDSSDSSDSSDSKSDSSK 628
Score = 35.8 bits (81), Expect = 0.069
Identities = 29/145 (20%), Positives = 62/145 (42%), Gaps = 4/145 (2%)
Query: 244 SQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTEDDF 303
S S+ S+ + +S+ + S++++ S + S+ SS +S S + + + D
Sbjct: 740 SSDSSDSSDSSNSSDSSDSSDSSNSSDSS-DSSDSSDSSDSSNSSDS---NDSSNSSDSS 795
Query: 304 PSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSNDTDSSHDPQ 363
SS + + +S+ S + + S N + S S + + + + S+ +D S
Sbjct: 796 DSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDS 855
Query: 364 EEKAVSGKGNRTVGSRHVQNGLDSS 388
++ S + + S N DSS
Sbjct: 856 SNRSDSSNSSDSSDSSDSSNSSDSS 880
Score = 34.7 bits (78), Expect = 0.15
Identities = 34/152 (22%), Positives = 55/152 (36%), Gaps = 29/152 (19%)
Query: 234 QQLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKDCSRLT---NGPSNGSSSRQRTSGS 290
+ +A Q+ Q + + S E +E S + S +T N NG+ + T G+
Sbjct: 174 EDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGT 233
Query: 291 GFHR-----------------EGNTTEDDFPSSPGNGNKSSNSSEERTGRGGSGYVNQLS 333
G E + DD GNG SSN+S+ + G+
Sbjct: 234 GEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQ---------D 284
Query: 334 AGYESVDSPTGSENSLTHQSNDTDSSHDPQEE 365
G E + +NS + + D + DP E
Sbjct: 285 HGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNE 316
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 49.7 bits (117), Expect = 5e-06
Identities = 75/315 (23%), Positives = 126/315 (40%), Gaps = 39/315 (12%)
Query: 10 KVRLSETDFKVMARDE----LILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQ 65
K S+ D K+ E L + +++ +++Q L+ +L +E EK Q
Sbjct: 303 KTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQL 362
Query: 66 QQESA----------RRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDP 115
++E + + IL +L+ E+ + + K V QL + +
Sbjct: 363 EKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEA 422
Query: 116 AI---NLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLI----QEN 168
A N L+ + E+ +T+ ++A+ F + Q L+ + I Q
Sbjct: 423 ATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAK 482
Query: 169 QELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQ 228
+EL Q SQ A+L A++A L S LN I Q D+E+ G L+QQ
Sbjct: 483 EEL-EQASQAHGARLTAQVA-------SLTSELTTLNATIQQQDQELAG-------LKQQ 527
Query: 229 LKETRQQLAQYQQQQSQASAPSTSRT-TASEPVEQSEATSKDCSRLTNGPSNGSSSRQRT 287
KE + QLAQ QQQ QAS + S ++Q E K+ + + + T
Sbjct: 528 AKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLAT 587
Query: 288 SGSGFHREGNTTEDD 302
+ RE + E D
Sbjct: 588 AAE--EREASLRERD 600
Score = 40.4 bits (93), Expect = 0.003
Identities = 60/302 (19%), Positives = 113/302 (37%), Gaps = 37/302 (12%)
Query: 3 NEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKL 62
N L +V + ET+ + +L+ +E Q L TDL S+ ++ L +++E+L
Sbjct: 428 NNTQLQARVEMLETE-RGQQEAKLLAERGHFEEEKQQLSSLITDLQSS-ISNLSQAKEEL 485
Query: 63 KQQQQESARRENI----LVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTM-----V 113
+Q Q R L L T +Q+ ++ LKQ + AQL T+
Sbjct: 486 EQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQA 545
Query: 114 DPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTG------------------- 154
+ ++ L+Q + +L++ + A + Q
Sbjct: 546 SQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQ 605
Query: 155 -----KKLMAKCRMLIQENQELG--RQLSQGRIAQLEAELALQKKYSEELKSSQDELNDF 207
K+ AK +L Q+ Q R +Q + Q + E A + EEL++ +
Sbjct: 606 LEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQE 665
Query: 208 IIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPSTSRTTASEPVEQSEATS 267
+ +V ++ + QQ+ E + + Q Q Q A S +E+ + +
Sbjct: 666 QHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRA 725
Query: 268 KD 269
D
Sbjct: 726 AD 727
Score = 40.0 bits (92), Expect = 0.004
Identities = 61/266 (22%), Positives = 105/266 (39%), Gaps = 29/266 (10%)
Query: 1 MTNEEPLPKKVRLSETDFKVMARDELILRWK--QYEAYVQALEGKYTDLNSNDVTGLRES 58
+ + L K++ + D K + IL+ K Q E ++ L+ +V G
Sbjct: 356 LEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQ-EKGEVLGDVLQ 414
Query: 59 EEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAIN 118
E LKQ+ A L R+ E E + ++ + + QL S + D +
Sbjct: 415 LETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSS 474
Query: 119 LFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQG 178
+ L Q K++LEQA G +L A+ L E L
Sbjct: 475 I------SNLSQAKEELEQASQA-----------HGARLTAQVASLTSELTTLN-----A 512
Query: 179 RIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQ 238
I Q + ELA K ++ K Q +L + Q ++ +G++ + L LK+ QQL +
Sbjct: 513 TIQQQDQELAGLK---QQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKE 569
Query: 239 Y-QQQQSQASAPSTSRTTASEPVEQS 263
++Q++ + TA+E E S
Sbjct: 570 VAEKQEATRQDHAQQLATAAEEREAS 595
Score = 38.1 bits (87), Expect = 0.014
Identities = 71/348 (20%), Positives = 136/348 (39%), Gaps = 66/348 (18%)
Query: 3 NEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKL 62
N + L K+ E VMA E + ++ +QA + + + LRE + L
Sbjct: 1238 NRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSL 1297
Query: 63 KQQQQESARRENILVMRLATKEQEMQECTTQI-----QYLKQVQQPSVAQLRSTMVDPAI 117
+++ ++ L L ++ + +E ++ ++ ++ Q S QL T +
Sbjct: 1298 REEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALV 1357
Query: 118 NLFF-----------------LKMKGELEQTKD-------KLEQAQNELS-----AWKFT 148
+ + + ELEQ+K +L +AQ EL K
Sbjct: 1358 SELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVA 1417
Query: 149 PDSQTGKKLMAKCR--------------MLIQENQELGRQLSQGRIAQLEAEL-ALQKKY 193
+T ++L A+ +L +EN+ LG + + GR LE EL ++KY
Sbjct: 1418 EQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGR-QFLEVELDQAREKY 1476
Query: 194 SEELKSSQDELNDFIIQLDEEV--------------EGMQSTILVLQQQLKETRQQL-AQ 238
+EL + + + + ++ E EG + +L +Q+ +E RQ+L AQ
Sbjct: 1477 VQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQ 1536
Query: 239 YQQQQSQASAPSTSRTTASEPVEQSEATSK-DCSRLTNGPSNGSSSRQ 285
+Q + + S+ + S+ SK +L + G S+Q
Sbjct: 1537 VEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQ 1584
Score = 35.8 bits (81), Expect = 0.069
Identities = 43/249 (17%), Positives = 105/249 (42%), Gaps = 13/249 (5%)
Query: 57 ESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDP- 115
+ +E K + E+A+ + + +R K+ + Q + ++ S A R+ P
Sbjct: 1062 KDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPK 1121
Query: 116 --AINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGR 173
A+ K++ + ++ +++ + + L A + + ++ L L ++ QELG
Sbjct: 1122 LEALRAEVSKLEQQCQKQQEQADSLERSLEAERASR-AERDSALETLQGQLEEKAQELGH 1180
Query: 174 QLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETR 233
SQ +A + ELA + ++ ++DE + + +E E S I L++++
Sbjct: 1181 --SQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILN 1238
Query: 234 QQLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFH 293
+Q+ + + + + + + S+ +E+ RL + +S+R S
Sbjct: 1239 RQVLEKEGESKELKRLVMAESEKSQKLEER-------LRLLQAETASNSARAAERSSALR 1291
Query: 294 REGNTTEDD 302
E + ++
Sbjct: 1292 EEVQSLREE 1300
Score = 35.4 bits (80), Expect = 0.091
Identities = 62/324 (19%), Positives = 135/324 (41%), Gaps = 78/324 (24%)
Query: 27 ILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARR----ENILVMRLAT 82
+ W++ Q E +Y + + L+E EK +Q+ QE+ + E+ ++++
Sbjct: 810 VAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISR 869
Query: 83 KEQEMQECTTQI-QYLKQVQQPSV-------------AQLRSTMVDPAINLFFLKMKGEL 128
++ E+ E + + L+QVQ+ V ++ +T + A ++ GE
Sbjct: 870 QQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQ 929
Query: 129 EQTKDKLEQAQNELSAWKFTP---DSQTGKKL---MAKCRMLIQENQELGRQLSQGRIAQ 182
++T + E + A P + Q G++ A + + +E +++G +L + R A
Sbjct: 930 QETASR-ELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAAL 988
Query: 183 LE---------------------------AELALQKKYSEELKSS-QDELNDFIIQL--- 211
+E A+LAL+K EL+ Q+ LN+ ++
Sbjct: 989 MESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATL 1048
Query: 212 --------------DEE---VEGMQST----ILVLQQQLKETRQQLAQYQQQQSQASAPS 250
D+E + G+++ + L+Q +K+ ++QLA+ +++ + S
Sbjct: 1049 QEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQ 1108
Query: 251 TSRTTASEPV-EQSEATSKDCSRL 273
+ +EP + EA + S+L
Sbjct: 1109 SEAAGRTEPTGPKLEALRAEVSKL 1132
Score = 29.6 bits (65), Expect = 5.0
Identities = 30/140 (21%), Positives = 58/140 (41%), Gaps = 1/140 (0%)
Query: 107 QLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQ 166
Q +D A + ++ + +L + Q E + + T K AK ++L +
Sbjct: 1463 QFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEE 1522
Query: 167 ENQ-ELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVL 225
+ + RQ ++ QLE Q K EEL + + ++++ +Q+
Sbjct: 1523 RQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGES 1582
Query: 226 QQQLKETRQQLAQYQQQQSQ 245
QQ+ + + QL + Q Q SQ
Sbjct: 1583 QQEAQRLQAQLNELQAQLSQ 1602
>gi|10864047 epidermal growth factor receptor pathway substrate
15-like 1 [Homo sapiens]
Length = 864
Score = 49.3 bits (116), Expect = 6e-06
Identities = 64/282 (22%), Positives = 114/282 (40%), Gaps = 41/282 (14%)
Query: 47 LNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQV---QQP 103
L S + TG++E ++ + Q+ + R + L + KE+ +++ T+++Q L+ +
Sbjct: 375 LGSGEFTGVKELDD-ISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETS 433
Query: 104 SVAQLRSTMVDPAINLFFL-----KMKGELEQTKDKLEQAQNELSAWKFTPDSQTG---- 154
S+ +L + D L + K++ L + K + +S+ K SQ
Sbjct: 434 SLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKS 493
Query: 155 -----KKLMAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFII 209
+ ++ L QE +L + + GR+ QLE + + LKS+QDE+N
Sbjct: 494 QEDDLNRAKSELNRLQQEETQLEQSIQAGRV-QLETII-------KSLKSTQDEINQ--- 542
Query: 210 QLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPS-TSRTTASEPVEQSEATSK 268
+S + L + +E + L QY Q A S T SE V +E S
Sbjct: 543 --------ARSKLSQLHESRQEAHRSLEQYDQVLDGAHGASLTDLANLSEGVSLAERGSF 594
Query: 269 DCSRLTNGPSNGSSSRQRTSGSGFHREGNTTEDDFPSSPGNG 310
+ P + + H + TED F S P G
Sbjct: 595 GA---MDDPFKNKALLFSNNTQELHPDPFQTEDPFKSDPFKG 633
>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
Length = 1219
Score = 49.3 bits (116), Expect = 6e-06
Identities = 58/245 (23%), Positives = 106/245 (43%), Gaps = 35/245 (14%)
Query: 4 EEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGK-----YTDLNSNDVTGLRES 58
+E L K R+ E + K+ ELI R ++Y + K T + L
Sbjct: 579 QEILEKSNRIEEQNDKI---SELIERNQRYVEQSNLMMEKRNNSLQTATENTQARVLHAE 635
Query: 59 EEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAIN 118
+EK K ++ +A + ++L + +E Q+Q + +++ + + + T
Sbjct: 636 QEKAKVTEELAAATAQVSHLQLKMTAHQKKETELQMQLTESLKETDLLRGQLT------- 688
Query: 119 LFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQG 178
K++ +L + ++ EQAQ+ KF + Q K+L K L +E +L
Sbjct: 689 ----KVQAKLSELQETSEQAQS-----KFKSEKQNRKQLELKVTSLEEELTDL------- 732
Query: 179 RIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQ 238
++E E +L+K SE K S E + ++DE + Q + L+Q LK+TR Q
Sbjct: 733 ---RVEKE-SLEKNLSERKKKSAQERSQAEEEIDEIRKSYQEELDKLRQLLKKTRVSTDQ 788
Query: 239 YQQQQ 243
+Q
Sbjct: 789 AAAEQ 793
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 49.3 bits (116), Expect = 6e-06
Identities = 43/212 (20%), Positives = 97/212 (45%), Gaps = 19/212 (8%)
Query: 43 KYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQ 102
K D ++V LRES + +QQQE+ R + ++ +QE+Q+ + + ++
Sbjct: 160 KERDQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKE 219
Query: 103 PSVAQLRSTMVD--------PAINLFFLKMKGELEQTKDKLEQAQ--NELSAWKFTPDSQ 152
+L+ D A+ + K K EL++ + +L++ + NE +A +
Sbjct: 220 KLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQM 279
Query: 153 TGKKLMAK-------CRMLIQENQELGRQL--SQGRIAQLEAELALQKKYSEELKSSQDE 203
KL + C L QENQ+ +L + + Q+ ++ K E++
Sbjct: 280 RNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHH 339
Query: 204 LNDFIIQLDEEVEGMQSTILVLQQQLKETRQQ 235
D ++++ E +++ I+ L+++++ +++Q
Sbjct: 340 TEDQKAEVEQHKETLKNQIVGLEREVEASKKQ 371
Score = 34.3 bits (77), Expect = 0.20
Identities = 15/77 (19%), Positives = 44/77 (57%)
Query: 166 QENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVL 225
Q+ E ++ ++ I+Q + E+ ++ + +++L + Q+ +++ Q+ I L
Sbjct: 183 QQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKAL 242
Query: 226 QQQLKETRQQLAQYQQQ 242
QQ +++++++L + +QQ
Sbjct: 243 QQYVQKSKEELQKLEQQ 259
Score = 30.8 bits (68), Expect = 2.2
Identities = 26/123 (21%), Positives = 55/123 (44%), Gaps = 5/123 (4%)
Query: 144 AWKFTPDSQTGKKLMAKCRMLI--QENQELGRQLSQGRIAQLEAELALQK--KYSEELKS 199
AWK DS K+ AK +L +E L + + QG ++ ++ ++ EE+
Sbjct: 102 AWKMV-DSAYDKEQKAKETILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTK 160
Query: 200 SQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPSTSRTTASEP 259
+D+L +++L E + ++ +E ++Q+QQ+ Q ++ E
Sbjct: 161 ERDQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEK 220
Query: 260 VEQ 262
+E+
Sbjct: 221 LEK 223
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 48.9 bits (115), Expect = 8e-06
Identities = 69/290 (23%), Positives = 131/290 (45%), Gaps = 31/290 (10%)
Query: 41 EGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTT----QIQY 96
EGK + + L E+E+K + ++ ++ + + K +EC + +I
Sbjct: 2689 EGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDL 2748
Query: 97 LKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKK 156
LK ++ L++T ++ EL++TK + N+L K +Q K
Sbjct: 2749 LKSSKEELNNSLKATT----------QILEELKKTKMDNLKYVNQLK--KENERAQGKMK 2796
Query: 157 LMAK-CRMLIQENQELGRQLSQGRIAQLEAELA--LQKKYSE---ELKSSQDELNDFIIQ 210
L+ K C+ L +E + L ++LSQ + AQ + + + K E E+K ++ L + +
Sbjct: 2797 LLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKE 2856
Query: 211 LDEEVEGMQSTILVLQQQLKETRQQL-AQYQQQQSQASAPSTSRTTASEPVEQ--SEATS 267
DE ++ S +L+ ++L++ ++ L Q SQ S + + PV S S
Sbjct: 2857 ADEYLDKYCS-LLISHEKLEKAKEMLETQVAHLCSQQSKQDSRGSPLLGPVVPGPSPIPS 2915
Query: 268 KDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTEDDFPSSPGNGNKSSNSS 317
RL++G + S RQR+SG + G T P++P + +K S +
Sbjct: 2916 VTEKRLSSGQNKASGKRQRSSGIWENGRGPT-----PATPESFSKKSKKA 2960
Score = 44.3 bits (103), Expect = 2e-04
Identities = 64/257 (24%), Positives = 99/257 (38%), Gaps = 44/257 (17%)
Query: 10 KVRLSETDFKVM--ARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQ 67
KV L E + KV+ RDEL+ QY+ KYT L L++ E L Q+Q
Sbjct: 326 KVELIEKE-KVLNKCRDELVRTTAQYDQ----ASTKYTALEQK----LKKLTEDLSCQRQ 376
Query: 68 ESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGE 127
+ L ++ KE+E QE ++ Q Q Q+++ + E
Sbjct: 377 NAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQ------------E 424
Query: 128 LEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQLEAEL 187
L+Q K+ Q EL D T K Q+L L + + AE
Sbjct: 425 LQQAKNMHNVLQAEL-------DKLTSVK------------QQLENNLEEFKQKLCRAEQ 465
Query: 188 ALQKKY--SEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQ 245
A Q EL+ S +E+ L E + L+ +LK +Q L Q Q +
Sbjct: 466 AFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEE 525
Query: 246 ASAPSTSRTTASEPVEQ 262
A +TS+ T +++
Sbjct: 526 MKAKNTSQETMLRDLQE 542
Score = 43.5 bits (101), Expect = 3e-04
Identities = 56/233 (24%), Positives = 98/233 (42%), Gaps = 37/233 (15%)
Query: 47 LNSNDVTGLRESEEKLKQQQQESARRENILVM-------RLATKEQEMQECTTQIQYLK- 98
+NS+ L+E E++ Q +++S+ +L R+A + + C + Q L
Sbjct: 2414 INSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSS 2473
Query: 99 QVQ--QPSVAQLRSTMVDPAINLFFLKMK-----GELEQTKDKLEQAQNELSAWKFTPDS 151
QV+ + AQL + + N L+ E+E K KLE+ E+S
Sbjct: 2474 QVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEIS-------- 2525
Query: 152 QTGKKLMAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQL 211
+ + IQ+ ++L +LSQ +E E L K+ + EL++ EL I L
Sbjct: 2526 --------RLKNQIQDQEQLVSKLSQ-----VEGEHQLWKEQNLELRNLTVELEQKIQVL 2572
Query: 212 DEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPSTSRTTASEPVEQSE 264
+ +Q T+ VLQ K +L + + + ++ TA E Q E
Sbjct: 2573 QSKNASLQDTLEVLQSSYKNLENEL-ELTKMDKMSFVEKVNKMTAKETELQRE 2624
Score = 41.6 bits (96), Expect = 0.001
Identities = 47/223 (21%), Positives = 92/223 (41%), Gaps = 29/223 (13%)
Query: 51 DVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRS 110
+V LR EKL+ + + +++ + +L +E+E +++ L++ Q S
Sbjct: 2113 EVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQEL 2172
Query: 111 TMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQE 170
++D K E+E K ++E+ L ++ + +K EN
Sbjct: 2173 VILDAE------NSKAEVETLKTQIEEMARSLKVFELDLVTLRSEK----------ENLT 2216
Query: 171 LGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLK 230
Q QG++++L+ L+ K EE + ++ IQ+ EE ++ + +LQ QLK
Sbjct: 2217 KQIQEKQGQLSELDKLLSSFKSLLEEKEQAE-------IQIKEE---SKTAVEMLQNQLK 2266
Query: 231 ETRQQLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKDCSRL 273
E + +A Q A S P+E+ +L
Sbjct: 2267 ELNEAVAALCGDQEIMKATEQS---LDPPIEEEHQLRNSIEKL 2306
Score = 40.8 bits (94), Expect = 0.002
Identities = 60/249 (24%), Positives = 101/249 (40%), Gaps = 37/249 (14%)
Query: 60 EKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLK-QVQQPSVAQLRSTMVDPAIN 118
++LK Q QE + N L +RL E+EM+ + Q L+ Q+++ V + V
Sbjct: 281 DQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKV----- 335
Query: 119 LFFLKMKGELEQTKDKLEQAQNELSAW-----KFTPDSQTGKKLMAKCRMLIQE------ 167
K + EL +T + +QA + +A K T D ++ R +++
Sbjct: 336 --LNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKE 393
Query: 168 ---NQELGRQ------LSQGRI---AQLEAELALQKKYSEELKSSQDELNDFIIQLDEEV 215
+EL RQ L Q I A+L EL K L++ D+L QL+ +
Sbjct: 394 KEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNL 453
Query: 216 EGMQSTILVLQQ-----QLKETRQQLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKDC 270
E + + +Q Q+KE + + + ++ S S A E V EA K+
Sbjct: 454 EEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKARE-VCHLEAELKNI 512
Query: 271 SRLTNGPSN 279
+ N N
Sbjct: 513 KQCLNQSQN 521
Score = 40.0 bits (92), Expect = 0.004
Identities = 53/290 (18%), Positives = 132/290 (45%), Gaps = 33/290 (11%)
Query: 5 EPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSN------DVTGLRES 58
E L +++++SE + ++ +IL + +A V+ L+ + ++ + D+ LR
Sbjct: 2157 ENLERELQMSEEN-----QELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSE 2211
Query: 59 EEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAIN 118
+E L +Q QE + + L L++ + ++E +K+ + +V L++ + + +N
Sbjct: 2212 KENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKE--LN 2269
Query: 119 LFFLKMKGELEQTK----------DKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQEN 168
+ G+ E K ++ Q +N + + ++ K+L C + +
Sbjct: 2270 EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQL---CVLQQLKE 2326
Query: 169 QELGRQLSQGRIAQLEAELALQKKYSE----ELKSSQDELNDFIIQLD---EEVEGMQST 221
E L +GR+ LE EL + + E E ++S+ E+ +++ + + G++
Sbjct: 2327 SEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELD 2386
Query: 222 ILVLQQQLKETRQQLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKDCS 271
++ ++ + + +L + Q++ S+ ++S + EQ + K+ S
Sbjct: 2387 VVTIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKS 2436
Score = 36.6 bits (83), Expect = 0.041
Identities = 31/120 (25%), Positives = 58/120 (48%), Gaps = 7/120 (5%)
Query: 122 LKMKGELEQTKDKLEQ------AQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQL 175
+++KGE+E+ K EQ A+ K D+ + ++A+ + EN+E QL
Sbjct: 857 VQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSAL-ENKEKELQL 915
Query: 176 SQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQ 235
++ +AE+ KK + L+ S EL L E + M S I + +++++E Q+
Sbjct: 916 LNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQE 975
Score = 33.5 bits (75), Expect = 0.34
Identities = 39/212 (18%), Positives = 87/212 (41%), Gaps = 12/212 (5%)
Query: 159 AKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEV-EG 217
++CR+ ++ + + Q R+ LE L QK+ + +L+ +EL +Q+ E+ E
Sbjct: 812 SECRLEADQSPK-NSAILQNRVDSLEFSLESQKQMNSDLQKQCEEL----VQIKGEIEEN 866
Query: 218 MQSTILVLQQQLKETRQQLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKDCSRLTNGP 277
+ + Q + ET Q++++ Q+ S + +E + E K+ L +
Sbjct: 867 LMKAEQMHQSFVAETSQRISKLQED------TSAHQNVVAETLSALENKEKELQLLNDKV 920
Query: 278 SNGSSSRQRTSGSGFHREGNTTEDDFPSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYE 337
+ Q S E + E S + K SS + + Q + +
Sbjct: 921 ETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLK 980
Query: 338 SVDSPTGSENSLTHQSNDTDSSHDPQEEKAVS 369
+++ E Q +++ +++ + EK++S
Sbjct: 981 EINASLNQEKMNLIQKSESFANYIDEREKSIS 1012
Score = 32.7 bits (73), Expect = 0.59
Identities = 62/303 (20%), Positives = 119/303 (39%), Gaps = 53/303 (17%)
Query: 3 NEEPLPKKVRLSETDFKVMARDELILR--WKQYEAYVQALEGKYTDLNSNDVTGLRESEE 60
++E L K+ E + ++ L LR + E +Q L+ K L D + +S
Sbjct: 2533 DQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQ--DTLEVLQSSY 2590
Query: 61 KLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLF 120
K + + E + + M K +M T++Q A+L+ + L
Sbjct: 2591 KNLENELELTKMDK---MSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLA 2647
Query: 121 --FLKMKGELEQTKDKLEQAQNELSAWKFTPD-------SQTGK--KLMAKCRMLIQENQ 169
+ E++ +KD+L++ E S K + D + GK + +A+ ++ + E +
Sbjct: 2648 GELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAE 2707
Query: 170 ELGRQLSQGRIAQLEAE--------------LALQKKYSEELKSSQDELND--------- 206
+ + L Q E E L+ QK + LKSS++ELN+
Sbjct: 2708 KKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQIL 2767
Query: 207 ------------FIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPSTSRT 254
++ QL +E E Q + +L + K+ ++ Q++ SQ A +
Sbjct: 2768 EELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQK 2827
Query: 255 TAS 257
T +
Sbjct: 2828 TGT 2830
Score = 30.4 bits (67), Expect = 2.9
Identities = 45/201 (22%), Positives = 83/201 (41%), Gaps = 25/201 (12%)
Query: 48 NSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQ-ECTTQIQYLKQVQQPSVA 106
N++ T LR+ +EK+ QQ+ + ++LA + E Q +C+ Q L + ++ +
Sbjct: 530 NTSQETMLRDLQEKINQQENSLTLEK----LKLAVADLEKQRDCS---QDLLKKREHHIE 582
Query: 107 QLRSTMVDPAINLFFLKMKGELEQTK-DKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLI 165
QL + L EL++ + ++L++ + S WK +KL+ +
Sbjct: 583 QLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWK-----SENEKLLTQ----- 632
Query: 166 QENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVL 225
E ++ Q +I LE L Q+ S E L L E+ + + VL
Sbjct: 633 ---MESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHN---VL 686
Query: 226 QQQLKETRQQLAQYQQQQSQA 246
+ E Q Y + Q +A
Sbjct: 687 DSKSVEVETQKLAYMELQQKA 707
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 48.5 bits (114), Expect = 1e-05
Identities = 49/271 (18%), Positives = 127/271 (46%), Gaps = 24/271 (8%)
Query: 2 TNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEK 61
T++ PLP++ ++ E + +V ++ + ++ E V+ EG+ + +RE E +
Sbjct: 43 TDKIPLPQEGQVREQEGQVREQEGQV---REQEGQVREQEGQVREQEGQ----VREQEGQ 95
Query: 62 LKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFF 121
+++Q+ + +E ++ +E +++E Q++ + + Q+R
Sbjct: 96 VREQEGQVREQEG----QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR----- 146
Query: 122 LKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIA 181
+ +G++ + + ++ + + ++ + Q G+ + ++ QE Q +G Q +G++
Sbjct: 147 -EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ-MGEQ--EGQMG 202
Query: 182 QLEAELALQK----KYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLA 237
+ E ++ Q+ K E++ ++++ Q+ E+ E +Q +Q+Q ++ R+Q
Sbjct: 203 EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEE 262
Query: 238 QYQQQQSQASAPSTSRTTASEPVEQSEATSK 268
Q ++Q+ Q E EQ E T +
Sbjct: 263 QMREQEEQMREQEEQMLKQKEQTEQEEQTGE 293
Score = 41.2 bits (95), Expect = 0.002
Identities = 37/196 (18%), Positives = 92/196 (46%), Gaps = 24/196 (12%)
Query: 55 LRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVD 114
+R+ EE++++Q+++ +E ++ + EQE Q + Q +Q +Q +
Sbjct: 257 MRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQE------- 309
Query: 115 PAINLFFLKMKGELEQTKDKLEQ-AQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGR 173
+M+ + EQ +++ EQ + E W+ K+ M K + E QE
Sbjct: 310 -------EQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGE-QEEQM 361
Query: 174 QLSQGRIAQLEAELALQ----KKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQL 229
Q + ++ + E ++ Q +K E+++ ++++ + Q+ E+ E M+ ++Q+
Sbjct: 362 QKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQ----EEQM 417
Query: 230 KETRQQLAQYQQQQSQ 245
E ++Q+ + ++ +
Sbjct: 418 GEQKEQMRKQEEHMGE 433
Score = 29.6 bits (65), Expect = 5.0
Identities = 36/187 (19%), Positives = 82/187 (43%), Gaps = 19/187 (10%)
Query: 4 EEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLK 63
EE + K+ + M E +R ++ + Q + + + +RE EE+++
Sbjct: 247 EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306
Query: 64 QQQQESARRENIL---VMRLATKEQEMQECTTQI-----QYLKQVQQPSVAQLRSTMVDP 115
+Q+++ +E + ++ +E++M E Q+ Q KQ +Q + + +
Sbjct: 307 EQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEE 366
Query: 116 AINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTG--KKLMAKCRMLIQENQE-LG 172
+ +M+ + EQ + + EQ + + + Q G K+ M + + ++E +E +G
Sbjct: 367 QVRKQEEQMRKQEEQMRKQEEQMRKQ--------EEQMGEQKEQMGEQKEQMREQEEQMG 418
Query: 173 RQLSQGR 179
Q Q R
Sbjct: 419 EQKEQMR 425
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 48.5 bits (114), Expect = 1e-05
Identities = 55/232 (23%), Positives = 105/232 (45%), Gaps = 46/232 (19%)
Query: 52 VTGLRESEEKLKQQQQESARRENILVMRLATKEQEM---QECTTQIQYLKQVQQPSVAQL 108
+ GL E ++K K+ Q +N L+ +++TK+ E+ QE T++ L Q Q ++++
Sbjct: 1849 IAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRV 1908
Query: 109 RSTMVDPAINLFFLKMKGELEQTKDKLEQA-QNELSAWKFT--------PDSQTGKKL-- 157
K+K E+ KD LE+ N+L+ + D+Q +L
Sbjct: 1909 T-------------KLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLE 1955
Query: 158 --MAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEV 215
M + + E +E +QL + + + E ++K+Y E+++ +Q E
Sbjct: 1956 SEMKNLKKCVSELEEEKQQLVKEKT---KVESEIRKEYLEKIQGAQKE------------ 2000
Query: 216 EGMQSTILVLQQQLKETRQQLAQYQQQ--QSQASAPSTSRTTASEPVEQSEA 265
G +S LQ+ LKE +Q++ Q Q+ + Q + RT + Q+E+
Sbjct: 2001 PGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTES 2052
Score = 42.4 bits (98), Expect = 7e-04
Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 6/134 (4%)
Query: 123 KMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAK-CRMLIQENQELGRQLSQGRIA 181
+M +E+ K + + +++ W+ +QT +L K C L EN+EL QL + R
Sbjct: 2242 QMSIHMEELKINISRLEHDKQIWE--SKAQTEVQLQQKVCDTLQGENKELLSQLEETRHL 2299
Query: 182 QLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQ 241
++ L K SE LKS +D+L D L++ E + +++QQ + + Y+Q
Sbjct: 2300 YHSSQNELAKLESE-LKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQ 2358
Query: 242 QQS--QASAPSTSR 253
++ QAS TSR
Sbjct: 2359 LETDLQASRELTSR 2372
Score = 41.2 bits (95), Expect = 0.002
Identities = 57/254 (22%), Positives = 103/254 (40%), Gaps = 49/254 (19%)
Query: 31 KQYEAYVQALEGKYTDLN--SNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQ 88
K+YE +Q+ E + + V +R+ +++L + + + + +L EQEM+
Sbjct: 1613 KEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEME 1672
Query: 89 ECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFT 148
E +++ + +Q + ELE+ D+L +
Sbjct: 1673 EMKEKMRKFAKSKQQKIL--------------------ELEEENDRLRA--------EVH 1704
Query: 149 PDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFI 208
P T K+ M L+ N + +L + ++E E L KK+ + L S +D L++ +
Sbjct: 1705 PAGDTAKECM---ETLLSSNASMKEELER---VKMEYE-TLSKKF-QSLMSEKDSLSEEV 1756
Query: 209 IQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQS-------QASAPSTSRTTASEPVE 261
L ++EG S L+ K Q + QS Q S ++R T SE V
Sbjct: 1757 QDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVP 1816
Query: 262 QSE----ATSKDCS 271
++ A SKD S
Sbjct: 1817 SAKSANPAVSKDFS 1830
Score = 41.2 bits (95), Expect = 0.002
Identities = 43/184 (23%), Positives = 88/184 (47%), Gaps = 25/184 (13%)
Query: 52 VTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRST 111
++ L+ +++ Q+ R +++ K+Q +QE + LK+ + LRS
Sbjct: 2466 MSSLQNDRDRIVGDYQQLEERHLSIILE---KDQLIQEAAAENNKLKE----EIRGLRSH 2518
Query: 112 MVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQEL 171
M D +N K+ EL Q ++ L Q DSQ + L + +Q+N+EL
Sbjct: 2519 MDD--LNSENAKLDAELIQYREDLNQVIT-------IKDSQQKQLLEVQ----LQQNKEL 2565
Query: 172 GRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKE 231
+ + A+LE +L ++ +E+L+ S + L + L +E+E ++ +I L +Q+
Sbjct: 2566 -----ENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTA 2620
Query: 232 TRQQ 235
+++
Sbjct: 2621 LQEE 2624
Score = 36.6 bits (83), Expect = 0.041
Identities = 45/209 (21%), Positives = 92/209 (44%), Gaps = 16/209 (7%)
Query: 41 EGKYTDLNSNDVTGLRESEEK---LKQQQQESARRENILVMRLATKEQEMQECTTQIQYL 97
E K++D + +R E+ LK Q ++ + L + ++ E + Q ++ Q
Sbjct: 2212 ERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTE 2271
Query: 98 KQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKL 157
Q+QQ L+ + + +LE+T+ +QNEL+ K + ++ K
Sbjct: 2272 VQLQQKVCDTLQGENKE---------LLSQLEETRHLYHSSQNELA--KLESELKSLKDQ 2320
Query: 158 MAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEG 217
+ +++ +E L +G I Q EA++ K E+L++ + +L EE+
Sbjct: 2321 LTDLSNSLEKCKEQKGNL-EGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINM 2379
Query: 218 MQSTILVLQQQLKETRQ-QLAQYQQQQSQ 245
+ I+ L +E Q +A+ +QQ +
Sbjct: 2380 KEQKIISLLSGKEEAIQVAIAELRQQHDK 2408
Score = 35.4 bits (80), Expect = 0.091
Identities = 53/269 (19%), Positives = 111/269 (41%), Gaps = 22/269 (8%)
Query: 3 NEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSND-VTGLRESEEK 61
+EE L K + S + M +++ + ++ E + L+ + T + E EE
Sbjct: 128 SEEQLSKHDKSSTEE--EMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEF 185
Query: 62 LKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFF 121
+ +QQ + E I ++ + + ++ Q+ K + + +L + +
Sbjct: 186 VMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQAD 245
Query: 122 LK--MKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGR 179
++ M+ +L + KLE+ + L +Q L + Q NQ L +QL Q
Sbjct: 246 VETEMQQKLRVLQRKLEEHEESLVG-----RAQVVDLLQQELTAAEQRNQILSQQLQQ-- 298
Query: 180 IAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQY 239
+EAE +++ ++E + +++ EV + + LQ+++ +Q
Sbjct: 299 ---MEAE---HNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQF--- 349
Query: 240 QQQQSQASAPSTSRTTASEPVEQSEATSK 268
+Q QA A SR +A E ++E K
Sbjct: 350 -EQAGQAQAELESRYSALEQKHKAEMEEK 377
Score = 35.4 bits (80), Expect = 0.091
Identities = 51/238 (21%), Positives = 98/238 (41%), Gaps = 34/238 (14%)
Query: 59 EEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAIN 118
E ++K+Q + ++ + L +E++ ++Q Q LK Q + S D + N
Sbjct: 2963 ERRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPDGSQN 3022
Query: 119 LFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQL--- 175
L + E E + +L + E+ + ++L + L++E L QL
Sbjct: 3023 LVY-----ETELLRTQLNDSLKEIHQKELRI-----QQLNSNFSQLLEEKNTLSIQLCDT 3072
Query: 176 ------SQGRIAQLEAELALQKKYSEELKS----------SQDELNDFIIQLD-EEVEGM 218
+Q L A+ +K +EL++ + E N + D EE+
Sbjct: 3073 SQSLRENQQHYGDLLNHCAVLEKQVQELQAGPLNIDVAPGAPQEKNGVHRKSDPEELREP 3132
Query: 219 QSTILVLQQQLKETRQQLAQ----YQQQQSQASAPSTSRTTASEPVEQSEATSKDCSR 272
Q + QQQL TRQ++ + ++++ Q A + + A E + + E + D SR
Sbjct: 3133 QQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAAENALSVAEEQIRRLEHSEWDSSR 3190
Score = 35.0 bits (79), Expect = 0.12
Identities = 44/212 (20%), Positives = 86/212 (40%), Gaps = 29/212 (13%)
Query: 43 KYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQ 102
K D NS+ T L E ++L Q +E + + +R K+ EM + Q +
Sbjct: 730 KNADNNSSAFTALSEERDQLLSQVKELSM---VTELRAQVKQLEMNLAEAERQRRLDYES 786
Query: 103 PSVAQLRSTMVDPAINLFFLKMKGELEQTKD-KLEQAQNELSAWKFTPDSQTGKKLMAKC 161
+ ++ I+ ++ K +KD K+E QNEL
Sbjct: 787 QTA---HDNLLTEQIHSLSIEAK-----SKDVKIEVLQNELD----------------DV 822
Query: 162 RMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQST 221
++ E L R L Q ++ E+E+ + + S +EL+ + Q + E+ M
Sbjct: 823 QLQFSEQSTLIRSL-QSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQL 881
Query: 222 ILVLQQQLKETRQQLAQYQQQQSQASAPSTSR 253
+L ++ ++ +Q + + QQ ++ S T +
Sbjct: 882 LLEKKRDVETLQQTIEEKDQQVTEISFSMTEK 913
Score = 34.7 bits (78), Expect = 0.15
Identities = 39/143 (27%), Positives = 65/143 (45%), Gaps = 20/143 (13%)
Query: 156 KLMAKCRMLIQENQELGRQLSQG---RIAQLEAELALQKKYSEELKSSQDELNDFIIQLD 212
+L K L +E ++L ++L + R A L+ ++ EELK +D+ N Q D
Sbjct: 1161 ELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFD 1220
Query: 213 E---EVEGMQSTILVLQQQLKETRQ-QLAQYQQQQSQASAP-------STSRTTASEPVE 261
E E E + + LQ Q++E+ +L QQ+S +S P + ++PV
Sbjct: 1221 EQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVL 1280
Query: 262 QSE------ATSKDCSRLTNGPS 278
+S + S+D S L G S
Sbjct: 1281 ESNLCPDWPSHSEDASALQGGTS 1303
Score = 33.1 bits (74), Expect = 0.45
Identities = 43/216 (19%), Positives = 88/216 (40%), Gaps = 17/216 (7%)
Query: 31 KQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQEC 90
+Q EA +Q + Y L T L+ S E + +E +E ++ L+ KE+ +Q
Sbjct: 2343 RQQEADIQNSKFSYEQLE----TDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQ-- 2396
Query: 91 TTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPD 150
I L+Q + +L + + L+ E+ K +++ + K
Sbjct: 2397 -VAIAELRQQHDKEIKELENLLSQEEEENIVLE-----EENKKAVDKTNQLMETLKTIKK 2450
Query: 151 SQTGKKLMAKCRMLIQENQELGRQLSQGRIAQLEAE-LALQKKYSEELKSSQDELNDFII 209
+K + + + R G QLE L++ + + ++ + E N
Sbjct: 2451 ENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENN---- 2506
Query: 210 QLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQ 245
+L EE+ G++S + L + + +L QY++ +Q
Sbjct: 2507 KLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQ 2542
Score = 31.6 bits (70), Expect = 1.3
Identities = 47/249 (18%), Positives = 106/249 (42%), Gaps = 46/249 (18%)
Query: 13 LSETDFKVMARDELILR--------WKQYEAYVQALEGKYTDLNS--NDVTGLRESEE-K 61
L + + +++++DE +L + Q +++ +A+ + + N++ R+SEE K
Sbjct: 2803 LEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGK 2862
Query: 62 LKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFF 121
+ Q S + ++ A + + ++ LK +QQ + Q+ +
Sbjct: 2863 QRSAAQPSTSPAEVQSLKKAMSSLQ-NDRDRLLKELKNLQQQYL-QINQEIT-------- 2912
Query: 122 LKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIA 181
EL K +L++ Q++ A++ + L QEN +L Q R+
Sbjct: 2913 -----ELHPLKAQLQEYQDKTKAFQIMQEE------------LRQENLSWQHELHQLRME 2955
Query: 182 QLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQ 241
+ E+ ++ + L + D+ D+++ +Q+ I L+ +T+ QYQ+
Sbjct: 2956 KSSWEIHERRMKEQYLMAISDK--------DQQLSHLQNLIRELRSSSSQTQPLKVQYQR 3007
Query: 242 QQSQASAPS 250
Q S ++ S
Sbjct: 3008 QASPETSAS 3016
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 48.5 bits (114), Expect = 1e-05
Identities = 55/229 (24%), Positives = 108/229 (47%), Gaps = 18/229 (7%)
Query: 62 LKQQQQESARRENILVMRLATKEQEMQECTTQI-QYLKQVQQPSVAQLRSTMVDPAINLF 120
L+Q + +NIL M L + E+Q Q Q + ++++ VA L + +
Sbjct: 1688 LRQMSKHKTELKNILDM-LQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQI 1746
Query: 121 FLKMKGELEQTKDKLEQAQNELSAWKFTPDS---QTGKKLMAKCRMLIQENQEL-GRQLS 176
+ KGE+E K LE+ + E+ + T +S Q+ + ++K + +QE ++ ++L+
Sbjct: 1747 SQQQKGEIEWQKQLLERDKREIE--RMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLA 1804
Query: 177 QGR--IAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQ 234
Q + +A E +++ E+L+ + +L + QL+ + + + I +QQQL+E R+
Sbjct: 1805 QTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKRE 1864
Query: 235 QLAQYQQQQSQA------SAPSTSRTTASEPVEQSEAT--SKDCSRLTN 275
+ Q++ + + TT + V SE T KD S N
Sbjct: 1865 AVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWAN 1913
Score = 33.9 bits (76), Expect = 0.26
Identities = 48/231 (20%), Positives = 98/231 (42%), Gaps = 26/231 (11%)
Query: 32 QYEAYVQALEGKYTDLNSNDVTG---LRESEEKLKQQQQESARRENILV---MRLATKEQ 85
Q E+ + LE + + N V LR + K +Q ++E IL +A K+
Sbjct: 1472 QTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDS 1531
Query: 86 EMQ-------ECTTQIQYL-KQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQ 137
+ Q + T ++Q L K ++ + V + + ELE+ K ++
Sbjct: 1532 DFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTS 1591
Query: 138 AQNELSAWKFTPDSQTGKK---LMAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYS 194
Q E++ D Q G K L ++Q +L L G E E+ + +
Sbjct: 1592 QQQEMAVL----DRQLGHKKEELHLLQGSMVQAKADLQEALRLG-----ETEVTEKCNHI 1642
Query: 195 EELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQ 245
E+KS +EL+ +L+ ++ ++ + +++Q++++ + L +Q S+
Sbjct: 1643 REVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSK 1693
Score = 31.6 bits (70), Expect = 1.3
Identities = 24/103 (23%), Positives = 44/103 (42%)
Query: 166 QENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVL 225
Q+ QE + S + +LE +L + +EELKS Q + I D+ + ++ ++
Sbjct: 258 QDRQEAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQ 317
Query: 226 QQQLKETRQQLAQYQQQQSQASAPSTSRTTASEPVEQSEATSK 268
+Q +E + L + Q + T +EQ A K
Sbjct: 318 KQSCEELKSDLNTKNELLKQKTIELTRACQKQYELEQELAFYK 360
Score = 29.3 bits (64), Expect = 6.5
Identities = 29/145 (20%), Positives = 64/145 (44%), Gaps = 22/145 (15%)
Query: 137 QAQNELSAWKFTPDSQTGKKLMAKCRM-----LIQENQELGRQLSQGRIAQLEAELALQK 191
Q++ E+ D +K +C + +Q+ Q+ + G + L EL ++K
Sbjct: 1351 QSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQ-KDFIDGNVESLMTELEIEK 1409
Query: 192 KYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPST 251
LK +D + +E+E ++ T+L + +L+E + LA+ + + S +
Sbjct: 1410 S----LKHHED--------IVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTK 1457
Query: 252 SR----TTASEPVEQSEATSKDCSR 272
+ T A + Q+E+ +++ R
Sbjct: 1458 NAVEKFTDAKRSLLQTESDAEELER 1482
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 48.1 bits (113), Expect = 1e-05
Identities = 52/231 (22%), Positives = 103/231 (44%), Gaps = 33/231 (14%)
Query: 59 EEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQ-------------QPSV 105
E++L QQQQE +++ +L + ++Q+ Q+ Q+Q +Q+ Q
Sbjct: 200 EQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQ 259
Query: 106 AQLRSTMVDPAI----NLFFLKMKGELEQTKDK--LEQAQNELSAWKFTP-------DSQ 152
AQL+ +++ L+ + +L+Q + + L+Q Q +L + P + +
Sbjct: 260 AQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEE 319
Query: 153 TGKKLM----AKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFI 208
+LM + L Q+ QEL RQ + + + + LQ K EEL+ + +L
Sbjct: 320 VELELMPVDLGSEQELEQQRQELERQQE---LERQQEQRQLQLKLQEELQQLEQQLEQQQ 376
Query: 209 IQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPSTSRTTASEP 259
QL+++ ++ T + L Q +E + +L Q + P+ A+ P
Sbjct: 377 QQLEQQEVQLELTPVELGAQQQEVQLELTPVQPELQLELVPAAGGGGAAVP 427
Score = 46.6 bits (109), Expect = 4e-05
Identities = 54/238 (22%), Positives = 97/238 (40%), Gaps = 9/238 (3%)
Query: 32 QYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEM--QE 89
Q E +Q LE + L++ + L+ QQQ + L K Q + QE
Sbjct: 86 QRELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQE 145
Query: 90 CTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTP 149
++Q + Q QQ Q++ + + +Q + EQ Q ++ +
Sbjct: 146 LKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQ 205
Query: 150 DSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQLEAE---LALQKKYSEELKSSQDELND 206
Q + + L+Q+ ++L +Q Q + QL+ + L LQ++ + + Q +
Sbjct: 206 QQQE----QLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQ 261
Query: 207 FIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPSTSRTTASEPVEQSE 264
QL E+ + L+LQQQ + +QQ Q QQQ + + EP E+ E
Sbjct: 262 LQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEE 319
Score = 45.4 bits (106), Expect = 9e-05
Identities = 47/224 (20%), Positives = 106/224 (47%), Gaps = 20/224 (8%)
Query: 23 RDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLAT 82
+ EL L +Q + Q ++ + + ++++E+ QQQE +++ + +L
Sbjct: 147 KPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQ-VQEQQLLQ 205
Query: 83 KEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNEL 142
++QE + +Q +Q+QQ Q + + L L+ +G+L+Q + +QAQ +
Sbjct: 206 QQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQ-QLLLLQQQGQLQQQLLQQQQAQLQQ 264
Query: 143 SAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQD 202
+ ++ + ++L+Q+ ++L +Q Q + Q + E+L+ Q
Sbjct: 265 QLLE-------QQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQ----------EQLQQQQL 307
Query: 203 ELNDFIIQLDEEVE-GMQSTILVLQQQLKETRQQLAQYQQQQSQ 245
+ + +EEVE + L +Q+L++ RQ+L + Q+ + Q
Sbjct: 308 QPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQ 351
Score = 32.0 bits (71), Expect = 1.0
Identities = 33/134 (24%), Positives = 60/134 (44%), Gaps = 26/134 (19%)
Query: 27 ILRWKQYEAYVQALEGKYTDLNSNDVTGLRES-----EEKLKQQQQESARRENILVMRLA 81
+L+ +Q + Q LE + L + +E +++L QQQQE +++ + L
Sbjct: 254 LLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLE 313
Query: 82 TKEQE-------------MQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGEL 128
+E+E QE Q Q L++ Q+ Q + + LK++ EL
Sbjct: 314 PEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQ--------LKLQEEL 365
Query: 129 EQTKDKLEQAQNEL 142
+Q + +LEQ Q +L
Sbjct: 366 QQLEQQLEQQQQQL 379
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 48.1 bits (113), Expect = 1e-05
Identities = 56/227 (24%), Positives = 94/227 (41%), Gaps = 18/227 (7%)
Query: 16 TDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENI 75
T + A++E+I +Q + Y++ GK N L E EK+ Q R
Sbjct: 798 TQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRK----LEEQLEKISHQDHSDKNRLLE 853
Query: 76 LVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKL 135
L RL E +E +++ Q S+ + S + A+ ++ +L Q K +L
Sbjct: 854 LETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLT--ALQAARAALESQLRQAKTEL 911
Query: 136 EQ----AQNELSAWKFTPDSQTGK--KLMAKCRMLIQENQELGRQLSQGRIAQLEAELAL 189
E+ A+ E+ A D K L C ++ +L QL+Q + + AEL
Sbjct: 912 EETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVIT----DLEEQLNQ--LTEDNAELNN 965
Query: 190 QKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQL 236
Q Y + ND I+QL EV+ ++ I + QL +Q +
Sbjct: 966 QNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTM 1012
Score = 38.5 bits (88), Expect = 0.011
Identities = 49/279 (17%), Positives = 116/279 (41%), Gaps = 28/279 (10%)
Query: 20 VMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMR 79
++ R E ++ A ++E K + S ++ ++ K++Q+ RR + +
Sbjct: 427 ILGRSESVVSGLDSPAKTSSMEKKLL-IKSKELQDSQDKCHKMEQEMTRLHRRVSEVEAV 485
Query: 80 LATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQ 139
L+ KE E++ TQ L+Q + + S +K LEQ + +E +Q
Sbjct: 486 LSQKEVELKASETQRSLLEQDLATYITECSS-------------LKRSLEQAR--MEVSQ 530
Query: 140 NELSAWKFTPDSQTGKKLMAKCR-----MLIQENQELGRQLSQGRIAQ------LEAELA 188
+ A + D + + + + + ++E + + QL + ++ E+EL
Sbjct: 531 EDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELR 590
Query: 189 LQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASA 248
+ +EE K E +++ ++ + L++ E + ++ + Q++ +A
Sbjct: 591 ESRLAAEEFKRKATECQHKLLKAKDQGKPEVGEYAKLEKINAEQQLKIQELQEKLEKAVK 650
Query: 249 PSTSRTTASEPVEQS-EATSKDCSRLTNGPSNGSSSRQR 286
ST T + + Q+ E ++ +L N + R++
Sbjct: 651 ASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKK 689
Score = 38.5 bits (88), Expect = 0.011
Identities = 58/299 (19%), Positives = 121/299 (40%), Gaps = 26/299 (8%)
Query: 19 KVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVM 78
K++ +EL + ++ + Q LE + ++ + ++K+ + EN++
Sbjct: 689 KLVEAEELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMM-Q 747
Query: 79 RLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPA-INLFFLKMKGELEQTKDKLEQ 137
R + E + ++ + + + L +V+ + N ++ E+
Sbjct: 748 RHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEE 807
Query: 138 AQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSE-- 195
+EL KF ++Q GK L A+ R L ++ +++ Q + LE E L++ E
Sbjct: 808 MISELRQQKFYLETQAGK-LEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHE 866
Query: 196 ----ELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQL--------------- 236
ELK EL + + + ++ +Q+ L+ QL++ + +L
Sbjct: 867 EQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALT 926
Query: 237 AQYQQQQSQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHRE 295
A + Q + A S T ++ EQ ++D + L N N S+Q SG + E
Sbjct: 927 AHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNN--QNFYLSKQLDEASGANDE 983
Score = 37.7 bits (86), Expect = 0.018
Identities = 41/198 (20%), Positives = 83/198 (41%), Gaps = 23/198 (11%)
Query: 63 KQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFL 122
KQ + S + I+ +R + ++Q Q Q + TM++ +
Sbjct: 972 KQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVM---- 1027
Query: 123 KMKGELEQTKDKLEQAQNELSAWKFT---PDSQTGKKLMAKCRMLIQENQELGR------ 173
+LE D+L + + + AW+ SQ ++ RML E Q R
Sbjct: 1028 ----DLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRIT 1083
Query: 174 ---QLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQL- 229
Q+ + + + +AE+ ++ +E K + L+D + L+++ ++ LQQ+L
Sbjct: 1084 ESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLE 1143
Query: 230 --KETRQQLAQYQQQQSQ 245
+E +Q+L + Q + Q
Sbjct: 1144 TERELKQRLLEEQAKLQQ 1161
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.121 0.320
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,360,712
Number of Sequences: 37866
Number of extensions: 670338
Number of successful extensions: 6950
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 178
Number of HSP's successfully gapped in prelim test: 751
Number of HSP's that attempted gapping in prelim test: 3972
Number of HSP's gapped (non-prelim): 2726
length of query: 396
length of database: 18,247,518
effective HSP length: 104
effective length of query: 292
effective length of database: 14,309,454
effective search space: 4178360568
effective search space used: 4178360568
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.