Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 21361116
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361116 versican isoform 1 [Homo sapiens]
(3396 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361116 versican isoform 1 [Homo sapiens] 6785 0.0
gi|187607300 versican isoform 2 [Homo sapiens] 721 0.0
gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens] 386 e-106
gi|126090892 aggrecan isoform 2 precursor [Homo sapiens] 363 2e-99
gi|126090883 aggrecan isoform 1 precursor [Homo sapiens] 363 2e-99
gi|38372931 brevican isoform 2 [Homo sapiens] 324 1e-87
gi|38372935 brevican isoform 1 [Homo sapiens] 324 1e-87
gi|4503053 hyaluronan and proteoglycan link protein 1 [Homo sapi... 217 1e-55
gi|30102948 hyaluronan and proteoglycan link protein 3 [Homo sap... 216 2e-55
gi|11141887 brain link protein-1 [Homo sapiens] 194 1e-48
gi|30794472 hyaluronan and proteoglycan link protein 4 [Homo sap... 191 8e-48
gi|91982772 mucin 17 [Homo sapiens] 180 2e-44
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 160 3e-38
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 125 5e-28
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] 125 5e-28
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens] 125 5e-28
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] 124 2e-27
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] 124 2e-27
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens] 124 2e-27
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens] 124 2e-27
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] 124 2e-27
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens] 124 2e-27
gi|83367077 mucin 16 [Homo sapiens] 120 2e-26
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ... 118 9e-26
gi|110624774 mannose receptor, C type 2 [Homo sapiens] 109 5e-23
gi|24041035 notch 2 preproprotein [Homo sapiens] 108 7e-23
gi|148833508 notch1 preproprotein [Homo sapiens] 97 2e-19
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 96 5e-19
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 95 1e-18
gi|134244285 Notch homolog 3 [Homo sapiens] 95 1e-18
>gi|21361116 versican isoform 1 [Homo sapiens]
Length = 3396
Score = 6785 bits (17603), Expect = 0.0
Identities = 3396/3396 (100%), Positives = 3396/3396 (100%)
Query: 1 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE 60
MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE
Sbjct: 1 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE 60
Query: 61 FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL 120
FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL
Sbjct: 61 FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL 120
Query: 121 LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA 180
LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA
Sbjct: 121 LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA 180
Query: 181 TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD 240
TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD
Sbjct: 181 TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD 240
Query: 241 VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS 300
VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS
Sbjct: 241 VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS 300
Query: 301 DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKPKEATTIDLSILA 360
DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKPKEATTIDLSILA
Sbjct: 301 DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKPKEATTIDLSILA 360
Query: 361 ETASPSLSKEPQMVSDRTTPIIPLVDELPVIPTEFPPVGNIVSFEQKATVQPQAITDSLA 420
ETASPSLSKEPQMVSDRTTPIIPLVDELPVIPTEFPPVGNIVSFEQKATVQPQAITDSLA
Sbjct: 361 ETASPSLSKEPQMVSDRTTPIIPLVDELPVIPTEFPPVGNIVSFEQKATVQPQAITDSLA 420
Query: 421 TKLPTPTGSTKKPWDMDDYSPSASGPLGKLDISEIKEEVLQSTTGVSHYATDSWDGVVED 480
TKLPTPTGSTKKPWDMDDYSPSASGPLGKLDISEIKEEVLQSTTGVSHYATDSWDGVVED
Sbjct: 421 TKLPTPTGSTKKPWDMDDYSPSASGPLGKLDISEIKEEVLQSTTGVSHYATDSWDGVVED 480
Query: 481 KQTQESVTQIEQIEVGPLVTSMEILKHIPSKEFPVTETPLVTARMILESKTEKKMVSTVS 540
KQTQESVTQIEQIEVGPLVTSMEILKHIPSKEFPVTETPLVTARMILESKTEKKMVSTVS
Sbjct: 481 KQTQESVTQIEQIEVGPLVTSMEILKHIPSKEFPVTETPLVTARMILESKTEKKMVSTVS 540
Query: 541 ELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVITVSKTSEDTIHTHLEDLESV 600
ELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVITVSKTSEDTIHTHLEDLESV
Sbjct: 541 ELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVITVSKTSEDTIHTHLEDLESV 600
Query: 601 SASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGKYLSTTPFPSQHRTEIELFPYSG 660
SASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGKYLSTTPFPSQHRTEIELFPYSG
Sbjct: 601 SASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGKYLSTTPFPSQHRTEIELFPYSG 660
Query: 661 DKILVEGISTVIYPSLQTEMTHRRERTETLIPEMRTDTYTDEIQEEITKSPFMGKTEEEV 720
DKILVEGISTVIYPSLQTEMTHRRERTETLIPEMRTDTYTDEIQEEITKSPFMGKTEEEV
Sbjct: 661 DKILVEGISTVIYPSLQTEMTHRRERTETLIPEMRTDTYTDEIQEEITKSPFMGKTEEEV 720
Query: 721 FSGMKLSTSLSEPIHVTESSVEMTKSFDFPTLITKLSAEPTEVRDMEEDFTATPGTTKYD 780
FSGMKLSTSLSEPIHVTESSVEMTKSFDFPTLITKLSAEPTEVRDMEEDFTATPGTTKYD
Sbjct: 721 FSGMKLSTSLSEPIHVTESSVEMTKSFDFPTLITKLSAEPTEVRDMEEDFTATPGTTKYD 780
Query: 781 ENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPLESTEPSASSKLPPALLTTVGMNGKD 840
ENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPLESTEPSASSKLPPALLTTVGMNGKD
Sbjct: 781 ENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPLESTEPSASSKLPPALLTTVGMNGKD 840
Query: 841 KDIPSFTEDGADEFTLIPDSTQKQLEEVTDEDIAAHGKFTIRFQPTTSTGIAEKSTLRDS 900
KDIPSFTEDGADEFTLIPDSTQKQLEEVTDEDIAAHGKFTIRFQPTTSTGIAEKSTLRDS
Sbjct: 841 KDIPSFTEDGADEFTLIPDSTQKQLEEVTDEDIAAHGKFTIRFQPTTSTGIAEKSTLRDS 900
Query: 901 TTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSST 960
TTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSST
Sbjct: 901 TTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSST 960
Query: 961 QEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEATISPET 1020
QEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEATISPET
Sbjct: 961 QEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEATISPET 1020
Query: 1021 MRTTKITEGTTQEEFPWKEQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDEL 1080
MRTTKITEGTTQEEFPWKEQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDEL
Sbjct: 1021 MRTTKITEGTTQEEFPWKEQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDEL 1080
Query: 1081 LTGSERVPVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKY 1140
LTGSERVPVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKY
Sbjct: 1081 LTGSERVPVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKY 1140
Query: 1141 ETEGSSTTGFTSSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATELIEFSTIK 1200
ETEGSSTTGFTSSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATELIEFSTIK
Sbjct: 1141 ETEGSSTTGFTSSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATELIEFSTIK 1200
Query: 1201 VTVPSDITTAFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPP 1260
VTVPSDITTAFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPP
Sbjct: 1201 VTVPSDITTAFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPP 1260
Query: 1261 TTLEDIVAKETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHP 1320
TTLEDIVAKETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHP
Sbjct: 1261 TTLEDIVAKETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHP 1320
Query: 1321 DINVYIIEVRENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIE 1380
DINVYIIEVRENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIE
Sbjct: 1321 DINVYIIEVRENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIE 1380
Query: 1381 IDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPS 1440
IDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPS
Sbjct: 1381 IDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPS 1440
Query: 1441 QNFSDSSESDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDV 1500
QNFSDSSESDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDV
Sbjct: 1441 QNFSDSSESDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDV 1500
Query: 1501 FPTVPFHEEFESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKI 1560
FPTVPFHEEFESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKI
Sbjct: 1501 FPTVPFHEEFESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKI 1560
Query: 1561 AFARATEVTFGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWV 1620
AFARATEVTFGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWV
Sbjct: 1561 AFARATEVTFGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWV 1620
Query: 1621 EATPRQVVELSGSSSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITES 1680
EATPRQVVELSGSSSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITES
Sbjct: 1621 EATPRQVVELSGSSSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITES 1680
Query: 1681 FFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEV 1740
FFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEV
Sbjct: 1681 FFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEV 1740
Query: 1741 YSSTQRSDQLILPFELESPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTETNTLE 1800
YSSTQRSDQLILPFELESPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTETNTLE
Sbjct: 1741 YSSTQRSDQLILPFELESPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTETNTLE 1800
Query: 1801 NLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAI 1860
NLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAI
Sbjct: 1801 NLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAI 1860
Query: 1861 QAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAE 1920
QAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAE
Sbjct: 1861 QAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAE 1920
Query: 1921 IRGFSTGFPLEEDFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVPTSVHI 1980
IRGFSTGFPLEEDFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVPTSVHI
Sbjct: 1921 IRGFSTGFPLEEDFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVPTSVHI 1980
Query: 1981 SHISDSEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQKFSGTASSI 2040
SHISDSEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQKFSGTASSI
Sbjct: 1981 SHISDSEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQKFSGTASSI 2040
Query: 2041 IDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQTIEPAKLWSR 2100
IDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQTIEPAKLWSR
Sbjct: 2041 IDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQTIEPAKLWSR 2100
Query: 2101 QEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTETELKTTDYSVLTT 2160
QEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTETELKTTDYSVLTT
Sbjct: 2101 QEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTETELKTTDYSVLTT 2160
Query: 2161 KKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATEKSHFFLATALVTESIPAEH 2220
KKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATEKSHFFLATALVTESIPAEH
Sbjct: 2161 KKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATEKSHFFLATALVTESIPAEH 2220
Query: 2221 VVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLPTESVNFTEVEQIN 2280
VVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLPTESVNFTEVEQIN
Sbjct: 2221 VVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLPTESVNFTEVEQIN 2280
Query: 2281 NTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVTSTTLIEILSDTG 2340
NTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVTSTTLIEILSDTG
Sbjct: 2281 NTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVTSTTLIEILSDTG 2340
Query: 2341 AEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSNKNSSTAEINETTTSSTD 2400
AEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSNKNSSTAEINETTTSSTD
Sbjct: 2341 AEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSNKNSSTAEINETTTSSTD 2400
Query: 2401 FLARAYGFEMAKEFVTSAPKPSDLYYEPSGEGSGEVDIVDSFHTSATTQATRQESSTTFV 2460
FLARAYGFEMAKEFVTSAPKPSDLYYEPSGEGSGEVDIVDSFHTSATTQATRQESSTTFV
Sbjct: 2401 FLARAYGFEMAKEFVTSAPKPSDLYYEPSGEGSGEVDIVDSFHTSATTQATRQESSTTFV 2460
Query: 2461 SDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSEQNKSSPDPTSTLSNTVSYERSTDGSF 2520
SDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSEQNKSSPDPTSTLSNTVSYERSTDGSF
Sbjct: 2461 SDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSEQNKSSPDPTSTLSNTVSYERSTDGSF 2520
Query: 2521 QDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDLILTITESTILEILPELTSDKNTIIDI 2580
QDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDLILTITESTILEILPELTSDKNTIIDI
Sbjct: 2521 QDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDLILTITESTILEILPELTSDKNTIIDI 2580
Query: 2581 DHTKPVYEDILGMQTDIDTEVPSEPHDSNDESNDDSTQVQEIYEAAVNLSLTEETFEGSA 2640
DHTKPVYEDILGMQTDIDTEVPSEPHDSNDESNDDSTQVQEIYEAAVNLSLTEETFEGSA
Sbjct: 2581 DHTKPVYEDILGMQTDIDTEVPSEPHDSNDESNDDSTQVQEIYEAAVNLSLTEETFEGSA 2640
Query: 2641 DVLASYTQATHDESMTYEDRSQLDHMGFHFTTGIPAPSTETELDVLLPTATSLPIPRKSA 2700
DVLASYTQATHDESMTYEDRSQLDHMGFHFTTGIPAPSTETELDVLLPTATSLPIPRKSA
Sbjct: 2641 DVLASYTQATHDESMTYEDRSQLDHMGFHFTTGIPAPSTETELDVLLPTATSLPIPRKSA 2700
Query: 2701 TVIPEIEGIKAEAKALDDMFESSTLSDGQAIADQSEIIPTLGQFERTQEEYEDKKHAGPS 2760
TVIPEIEGIKAEAKALDDMFESSTLSDGQAIADQSEIIPTLGQFERTQEEYEDKKHAGPS
Sbjct: 2701 TVIPEIEGIKAEAKALDDMFESSTLSDGQAIADQSEIIPTLGQFERTQEEYEDKKHAGPS 2760
Query: 2761 FQPEFSSGAEEALVDHTPYLSIATTHLMDQSVTEVPDVMEGSNPPYYTDTTLAVSTFAKL 2820
FQPEFSSGAEEALVDHTPYLSIATTHLMDQSVTEVPDVMEGSNPPYYTDTTLAVSTFAKL
Sbjct: 2761 FQPEFSSGAEEALVDHTPYLSIATTHLMDQSVTEVPDVMEGSNPPYYTDTTLAVSTFAKL 2820
Query: 2821 SSQTPSSPLTIYSGSEASGHTEIPQPSALPGIDVGSSVMSPQDSFKEIHVNIEATFKPSS 2880
SSQTPSSPLTIYSGSEASGHTEIPQPSALPGIDVGSSVMSPQDSFKEIHVNIEATFKPSS
Sbjct: 2821 SSQTPSSPLTIYSGSEASGHTEIPQPSALPGIDVGSSVMSPQDSFKEIHVNIEATFKPSS 2880
Query: 2881 EEYLHITEPPSLSPDTKLEPSEDDGKPELLEEMEASPTELIAVEGTEILQDFQNKTDGQV 2940
EEYLHITEPPSLSPDTKLEPSEDDGKPELLEEMEASPTELIAVEGTEILQDFQNKTDGQV
Sbjct: 2881 EEYLHITEPPSLSPDTKLEPSEDDGKPELLEEMEASPTELIAVEGTEILQDFQNKTDGQV 2940
Query: 2941 SGEAIKMFPTIKTPEAGTVITTADEIELEGATQWPHSTSASATYGVEAGVVPWLSPQTSE 3000
SGEAIKMFPTIKTPEAGTVITTADEIELEGATQWPHSTSASATYGVEAGVVPWLSPQTSE
Sbjct: 2941 SGEAIKMFPTIKTPEAGTVITTADEIELEGATQWPHSTSASATYGVEAGVVPWLSPQTSE 3000
Query: 3001 RPTLSSSPEINPETQAALIRGQDSTIAASEQQVAARILDSNDQATVNPVEFNTEVATPPF 3060
RPTLSSSPEINPETQAALIRGQDSTIAASEQQVAARILDSNDQATVNPVEFNTEVATPPF
Sbjct: 3001 RPTLSSSPEINPETQAALIRGQDSTIAASEQQVAARILDSNDQATVNPVEFNTEVATPPF 3060
Query: 3061 SLLETSNETDFLIGINEESVEGTAIYLPGPDRCKMNPCLNGGTCYPTETSYVCTCVPGYS 3120
SLLETSNETDFLIGINEESVEGTAIYLPGPDRCKMNPCLNGGTCYPTETSYVCTCVPGYS
Sbjct: 3061 SLLETSNETDFLIGINEESVEGTAIYLPGPDRCKMNPCLNGGTCYPTETSYVCTCVPGYS 3120
Query: 3121 GDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPSYVGALCEQDTETCDYGWHKFQGQC 3180
GDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPSYVGALCEQDTETCDYGWHKFQGQC
Sbjct: 3121 GDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPSYVGALCEQDTETCDYGWHKFQGQC 3180
Query: 3181 YKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQWIGLNDKMFEHDFRWT 3240
YKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQWIGLNDKMFEHDFRWT
Sbjct: 3181 YKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQWIGLNDKMFEHDFRWT 3240
Query: 3241 DGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYHLTYTCKKGTVACGQPP 3300
DGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYHLTYTCKKGTVACGQPP
Sbjct: 3241 DGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYHLTYTCKKGTVACGQPP 3300
Query: 3301 VVENAKTFGKMKPRYEINSLIRYHCKDGFIQRHLPTIRCLGNGRWAIPKITCMNPSAYQR 3360
VVENAKTFGKMKPRYEINSLIRYHCKDGFIQRHLPTIRCLGNGRWAIPKITCMNPSAYQR
Sbjct: 3301 VVENAKTFGKMKPRYEINSLIRYHCKDGFIQRHLPTIRCLGNGRWAIPKITCMNPSAYQR 3360
Query: 3361 TYSMKYFKNSSSAKDNSINTSKHDHRWSRRWQESRR 3396
TYSMKYFKNSSSAKDNSINTSKHDHRWSRRWQESRR
Sbjct: 3361 TYSMKYFKNSSSAKDNSINTSKHDHRWSRRWQESRR 3396
>gi|187607300 versican isoform 2 [Homo sapiens]
Length = 655
Score = 721 bits (1860), Expect = 0.0
Identities = 349/366 (95%), Positives = 354/366 (96%)
Query: 1 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE 60
MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE
Sbjct: 1 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE 60
Query: 61 FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL 120
FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL
Sbjct: 61 FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL 120
Query: 121 LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA 180
LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA
Sbjct: 121 LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA 180
Query: 181 TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD 240
TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD
Sbjct: 181 TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD 240
Query: 241 VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS 300
VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS
Sbjct: 241 VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS 300
Query: 301 DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKPKEATTIDLSILA 360
DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFK + ++ +
Sbjct: 301 DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRPDRCKMNPCLNG 360
Query: 361 ETASPS 366
T P+
Sbjct: 361 GTCYPT 366
Score = 692 bits (1787), Expect = 0.0
Identities = 307/307 (100%), Positives = 307/307 (100%)
Query: 3090 PDRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTF 3149
PDRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTF
Sbjct: 349 PDRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTF 408
Query: 3150 RCLCLPSYVGALCEQDTETCDYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILS 3209
RCLCLPSYVGALCEQDTETCDYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILS
Sbjct: 409 RCLCLPSYVGALCEQDTETCDYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILS 468
Query: 3210 HEEQMFVNRVGHDYQWIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVII 3269
HEEQMFVNRVGHDYQWIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVII
Sbjct: 469 HEEQMFVNRVGHDYQWIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVII 528
Query: 3270 WHENGQWNDVPCNYHLTYTCKKGTVACGQPPVVENAKTFGKMKPRYEINSLIRYHCKDGF 3329
WHENGQWNDVPCNYHLTYTCKKGTVACGQPPVVENAKTFGKMKPRYEINSLIRYHCKDGF
Sbjct: 529 WHENGQWNDVPCNYHLTYTCKKGTVACGQPPVVENAKTFGKMKPRYEINSLIRYHCKDGF 588
Query: 3330 IQRHLPTIRCLGNGRWAIPKITCMNPSAYQRTYSMKYFKNSSSAKDNSINTSKHDHRWSR 3389
IQRHLPTIRCLGNGRWAIPKITCMNPSAYQRTYSMKYFKNSSSAKDNSINTSKHDHRWSR
Sbjct: 589 IQRHLPTIRCLGNGRWAIPKITCMNPSAYQRTYSMKYFKNSSSAKDNSINTSKHDHRWSR 648
Query: 3390 RWQESRR 3396
RWQESRR
Sbjct: 649 RWQESRR 655
>gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens]
Length = 1321
Score = 386 bits (992), Expect = e-106
Identities = 199/520 (38%), Positives = 276/520 (53%), Gaps = 43/520 (8%)
Query: 2855 GSSVMSPQDSFKEIHVNIEATFKPSSEEYLHITEPPSLSP-DTKLEPSEDDGKPELLEEM 2913
G SP V + P+ E ++ E P+++P D+ + P+ D
Sbjct: 789 GLDASSPSAPLGSPGVFLVPKVTPNLEPWVATDEGPTVNPMDSTVTPAPSDASG------ 842
Query: 2914 EASPTELIAVEGTEILQDFQNKTDGQVSGEAIKMFPTIKTPEAGTVITTADEIELEGATQ 2973
I G+++ ++ ++ T + + T E G + L ++
Sbjct: 843 -------IWEPGSQVFEEAESTTLSPQVALDTSIVTPLTTLEQGDKVGVPAMSTLGSSSS 895
Query: 2974 WPHSTSASA--TYGVEAGVVPWLSPQTSERPTLSSSPEINPETQAALIRGQDSTIAASEQ 3031
PH T G VP + + P + P T A G+ +++++ E
Sbjct: 896 QPHPEPEDQVETQGTSGASVP------PHQSSPLGKPAVPPGTPTAASVGESASVSSGEP 949
Query: 3032 QVAARILDSNDQATVNPVEFNTEVATPPFSLLETSNETDFLIGINEESVEGTAIYLPGP- 3090
V + +T+ PV E LE + + EE G LPG
Sbjct: 950 TVPW-----DPSSTLLPVTLGIEDFE-----LEVLAGSPGVESFWEEVASGEEPALPGTP 999
Query: 3091 ----------DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGA 3140
D C+ NPCL+GGTC T Y C+C G++G+ CE+D D+C +PC NG
Sbjct: 1000 MNAGAEEVHSDPCENNPCLHGGTCNANGTMYGCSCDQGFAGENCEIDIDDCLCSPCENGG 1059
Query: 3141 TCVDGFNTFRCLCLPSYVGALCEQDTETCDYGWHKFQGQCYKYFAHRRTWDAAERECRLQ 3200
TC+D N F CLCLPSY G+ CE+DTE CD GWHKFQG CY+YFAHRR W+ AE++CR +
Sbjct: 1060 TCIDEVNGFVCLCLPSYGGSFCEKDTEGCDRGWHKFQGHCYRYFAHRRAWEDAEKDCRRR 1119
Query: 3201 GAHLTSILSHEEQMFVNRVGHDYQWIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFS 3260
HLTS+ S EE F+N GH+ WIGLND++ E DF+WTD + LQ+ENWR NQPD+FF+
Sbjct: 1120 SGHLTSVHSPEEHSFINSFGHENTWIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFA 1179
Query: 3261 AGEDCVVIIWHENGQWNDVPCNYHLTYTCKKGTVACGQPPVVENAKTFGKMKPRYEINSL 3320
GEDCVV++ HE+G+WNDVPCNY+L Y CKKGTV CG PP VENA G K +Y +++
Sbjct: 1180 GGEDCVVMVAHESGRWNDVPCNYNLPYVCKKGTVLCGPPPAVENASLIGARKAKYNVHAT 1239
Query: 3321 IRYHCKDGFIQRHLPTIRCLGNGRWAIPKITCMNPSAYQR 3360
+RY C +GF Q H+ TIRC NG+W P+I C P R
Sbjct: 1240 VRYQCNEGFAQHHVATIRCRSNGKWDRPQIVCTKPRRSHR 1279
Score = 338 bits (867), Expect = 5e-92
Identities = 183/429 (42%), Positives = 255/429 (59%), Gaps = 15/429 (3%)
Query: 21 LHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSEFLRIKWSKIEVDKNGKDLKE 80
LH K+G S V+ +L+ V+LPC F+ P + + RIKW+K+ + ++
Sbjct: 37 LHMQKLG-SGSVQAALAELVALPCLFTLQPRPSAARDAP---RIKWTKVRTASGQR--QD 90
Query: 81 TTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQ 140
+LVA++ +++ + ++GRVS+P++P +A+L + L ASD+GLYRC V+ GIED Q
Sbjct: 91 LPILVAKDNVVRVAKSWQGRVSLPSYPRRRANATLLLGPLRASDSGLYRCQVVRGIEDEQ 150
Query: 141 DTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIATPEQLFAAYEDGFEQCDAGW 200
D V L V GVVFHYR+A RY L F AQ+AC A+IA P L AA+EDGF+ CDAGW
Sbjct: 151 DLVPLEVTGVVFHYRSARDRYALTFAEAQEACRLSSAIIAAPRHLQAAFEDGFDNCDAGW 210
Query: 201 LADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYDVYCYVDHLDGDVFHLTVPSK 260
L+D+TVRYPI R GCYGD+ GVR+YG R+PQE YDVYC+ L G+VF++ +
Sbjct: 211 LSDRTVRYPITQSRPGCYGDRSSLPGVRSYGRRNPQELYDVYCFARELGGEVFYVGPARR 270
Query: 261 FTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLSDASVRHPVTVARAQCGGGLL 320
T A +C Q A LA+VG+L AW G DQCD GWL+D SVR+P+ R +CGG
Sbjct: 271 LTLAGARAQCRRQGAALASVGQLHLAWHEGLDQCDPGWLADGSVRYPIQTPRRRCGGPAP 330
Query: 321 GVRTLYRFENQTGFPPPDSRFDAYCFKPKEATTIDLSILAETASPSLSKEPQMVSDRTTP 380
GVRT+YRF N+TGFP P RFDAYCF+ T S + +PS E +++S P
Sbjct: 331 GVRTVYRFANRTGFPSPAERFDAYCFRAHHPT----SQHGDLETPSSGDEGEILSAEGPP 386
Query: 381 I---IPLVDELPVIPTEFPPVGNIVSFEQKATVQPQAITDSLATKLPTPTGSTKKPWDMD 437
+ P ++E V+ +F +VS ++ T+ + +S T PTP W
Sbjct: 387 VRELEPTLEEEEVVTPDFQE--PLVSSGEEETLILEEKQESQQTLSPTPGDPMLASWPTG 444
Query: 438 DYSPSASGP 446
+ S P
Sbjct: 445 EVWLSTVAP 453
>gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]
Length = 2416
Score = 363 bits (932), Expect = 2e-99
Identities = 347/1210 (28%), Positives = 540/1210 (44%), Gaps = 168/1210 (13%)
Query: 7 SILWMCSTL-IVTHALH----------KVKVGKSPPVRGSLSGKVSLPCHF-STMPTLPP 54
++LW+ TL ++T A+ V + + P+R L +++PC+F M +
Sbjct: 3 TLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPVTT 62
Query: 55 SYNTSEFL-RIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDA 113
+ +T+ RIKWS++ +K E +LVA G +++ Y+ +VS+P +P DA
Sbjct: 63 APSTAPLAPRIKWSRVSKEK------EVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDA 116
Query: 114 SLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACL 173
+L V L ++D+G+YRC+VM+GIED++ T+ + V G+VFHYRA ++RYTL+F+ AQ+ACL
Sbjct: 117 TLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACL 176
Query: 174 DVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFR 233
A+IATPEQL AAYEDGF QCDAGWLADQTVRYPI PR GCYGDK GVRTYG R
Sbjct: 177 QNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIR 236
Query: 234 SPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQ 293
ETYDVYC+ + ++G+VF+ T P KFTF+EAA EC ARLAT G+L AW+ G D
Sbjct: 237 DTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDM 296
Query: 294 CDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKPKEATT 353
C GWL+D SVR+P++ AR CGG LLGVRT+Y NQTG+P P SR+DA C+ ++
Sbjct: 297 CSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVD 356
Query: 354 I-----------DLSILAETASPSLSKEPQMVSD---RTTPIIPLVDELPVIPTEFPPVG 399
I D+++ T P+ +++ R + I+ + V P+ P
Sbjct: 357 IPENFFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPSPLEP-- 414
Query: 400 NIVSFEQKATVQPQAITDSLATKLPTPTGSTKKPWDMDDYSPSASGPLGKLDISEIKEEV 459
E+ T P+ + A ++ TG +PW + GP ++ +V
Sbjct: 415 -----EEPFTFAPEIGATAFA-EVENETGEATRPW---GFPTPGLGPATAFTSEDLVVQV 465
Query: 460 LQSTTGVSHYATDSWDGVV---EDKQTQESVT----QIEQIEVGPLVTSMEILKHIPSKE 512
+ G H GVV T+ S+T Q + G ++ S E L+
Sbjct: 466 -TAVPGQPHLP----GGVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAG 520
Query: 513 FPVTETPLVTARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLI 572
+ + A + + +VS + V G++D T G ST
Sbjct: 521 YEQCD-----AGWLRDQTVRYPIVSPRTPCV---------GDKDSSPGVRTYGVRPSTET 566
Query: 573 FDQI-------PEVITVSKTSEDTIHTHLEDLESVSAS-TTVSPLIMPDNNGSSMDDWEE 624
+D EV ++ + T LE ES +A+ T L + G +
Sbjct: 567 YDVYCFVDRLEGEVFFATRLEQFTFQEALEFCESHNATLATTGQLYAAWSRGL------D 620
Query: 625 RQTSGRITEEFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEGISTV-IYPSLQTEMTHR 683
+ +G + + L +Y TP P+ GDK G+ TV +YP+ QT +
Sbjct: 621 KCYAGWLADGSL-RYPIVTPRPA----------CGGDK---PGVRTVYLYPN-QTGLPDP 665
Query: 684 RERTETLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEM 743
R R + EE +P EE + + P+ ++V
Sbjct: 666 LSRHHAFC--FRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTAVPS 723
Query: 744 TKSFDFPTLITKLSAEPTEVRDMEEDFTAT-----PG--TTKYDENITTVLLAHGTLSVE 796
++ T I + + EP + E +T PG T T G + E
Sbjct: 724 GET----TAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSATE 779
Query: 797 AATVSKWSWDEDNTTSKPLESTEPSASSKLPPAL--LTTVGMNGKDKDIPSFTEDGADE- 853
+ S +E + + P S EPS S + P++ +V + ++ PS ++E
Sbjct: 780 VPSAS----EEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEP 835
Query: 854 ---------------FTLIPDSTQKQ-LEEVTDE-----DIAAHGKFTIRFQPTTSTGIA 892
+T +P S ++ +V+ + D++ H F+ + ++G+
Sbjct: 836 SASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLP 895
Query: 893 EKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVD--LSKPVSTVPQFAHTSE-- 948
DS+ +TST G G G+ E ++ + V +P A E
Sbjct: 896 SGDL--DSS------GLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGS 947
Query: 949 VEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVID 1008
G+ +S + E +S LS +P + VL + P +++ G PS ++L
Sbjct: 948 ASGVGDLSGLPSGE-VLETSASGVGDLSGLPSGE--VLETTAPGVEDISGLPSGEVL--- 1001
Query: 1009 QTRLEATISPETMRTTKITEGTTQE-EFPWKEQTAEKPVPALSSTAWTPKEAVTPLDEQE 1067
T +P + + G E P E + P + T E ++ L
Sbjct: 1002 -----ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGL--PS 1054
Query: 1068 GDGSAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIG 1127
G+ T E ++G VLETT G D S P G V E E ++ P
Sbjct: 1055 GEVLETTAPGVEDISGLPSGEVLETTAPGVEDIS-GLPSGEVLETAAPGVEDISGLPSGE 1113
Query: 1128 PKVSLSPGPE 1137
+ +PG E
Sbjct: 1114 VLETAAPGVE 1123
Score = 333 bits (853), Expect = 2e-90
Identities = 198/487 (40%), Positives = 255/487 (52%), Gaps = 58/487 (11%)
Query: 2924 EGTEILQDF-QNKTDGQVSGEAIKMFPTIKTPE----AGTVITTADEIELEGAT------ 2972
E T I +F + T+ +S E + P TP+ +G V T D + GAT
Sbjct: 1919 EVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGD---ISGATPVLPGS 1975
Query: 2973 -----QWPHSTSASATY---GVEAGVVPWLSPQTSERPTLSSSP----EINPETQAAL-I 3019
P S+S ++ Y G A P S + S P LS + E N E + L +
Sbjct: 1976 GVEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSSGLGV 2035
Query: 3020 RGQDSTIAASEQQVAARILDSNDQATVNPVEFNTEVATPPFSLLETSNETDFLIG--INE 3077
G T E A + S + T + V TE P + S + + G
Sbjct: 2036 SGSTLTFQEGEASAAPEV--SGESTTTSDV--GTEAPGLPSATPTASGDRTEISGDLSGH 2091
Query: 3078 ESVEGTAIYLPGPD---------------RCKMNPCLNGGT---CYPTETSYVCTCVPGY 3119
S G I P+ + + L G T TS +P
Sbjct: 2092 TSQLGVVISTSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPAS 2151
Query: 3120 ------SGDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPSYVGALCEQDTETCDYGW 3173
S C PC G TC + CLC P Y G C D E C+ GW
Sbjct: 2152 PEWKRESESTAAAPARSCAEEPCGAG-TCKETEGHVICLCPPGYTGEHCNIDQEVCEEGW 2210
Query: 3174 HKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQWIGLNDKMF 3233
+K+QG CY++F R TW AER CR Q +HL+SI++ EEQ FVN DYQWIGLND+
Sbjct: 2211 NKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTI 2270
Query: 3234 EHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYHLTYTCKKGT 3293
E DFRW+DG +Q+ENWRPNQPD+FF+AGEDCVV+IWHE G+WNDVPCNYHL +TCKKGT
Sbjct: 2271 EGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGT 2330
Query: 3294 VACGQPPVVENAKTFGKMKPRYEINSLIRYHCKDGFIQRHLPTIRCLGNGRWAIPKITCM 3353
VACG+PPVVE+A+TFG+ K RYEINSL+RY C +GF+QRH+PTIRC +G W P+ITC
Sbjct: 2331 VACGEPPVVEHARTFGQKKDRYEINSLVRYQCTEGFVQRHMPTIRCQPSGHWEEPQITCT 2390
Query: 3354 NPSAYQR 3360
+P+ Y+R
Sbjct: 2391 DPTTYKR 2397
Score = 40.8 bits (94), Expect = 0.023
Identities = 179/769 (23%), Positives = 269/769 (34%), Gaps = 105/769 (13%)
Query: 1356 PCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKH 1415
P EET V + EF EN+ E E + P +
Sbjct: 713 PVEEETTAVPSGETTAILEFTT--------EPENQTEWEPAYTPVGTSPLPGI------- 757
Query: 1416 LVTTVPKDPEAAEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTETTE 1475
L T P E+ G + PS + S P E S + +P S
Sbjct: 758 LPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFP----SEEPSPSEEPFPSVRPFP 813
Query: 1476 SLEVTWKPETYPET----SEHFSGGEPDVFPT--VPFHEEFESGTAKKGAESVTERDTEV 1529
S+E+ E +P SE S E P+ VP E S + GA V+ T
Sbjct: 814 SVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGS 873
Query: 1530 GHQAHEHTEPVSLFPEESSGEIAIDQESQ----KIAFARATEVTFGEEVEKSTSVTYTPT 1585
G + L + +SG + D +S + E E+ TPT
Sbjct: 874 GDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPT 933
Query: 1586 I--VPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWV------------EATPRQVVELS 1631
+ +PS A V + ++L T S V E T V ++S
Sbjct: 934 VGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDIS 993
Query: 1632 GSSSIPITEGSGEAEEDE---------DTMFTMVTDLSQRNTTDTLITL-----DTSRII 1677
G S + E + ED +T V D+S + + L T D S +
Sbjct: 994 GLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLP 1053
Query: 1678 TESFFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTAST 1737
+ E A + +S PS +V+ T D S + S V E E +G S
Sbjct: 1054 SGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISG-LPSGEVLETAAPGVEDISGLPSG 1112
Query: 1738 FEVYSSTQRSDQLI-LP----FELESPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPV 1792
+ ++ + + LP E +P V S + + + + + +
Sbjct: 1113 EVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVL 1172
Query: 1793 FTETNTLENL-GAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSS 1851
T +E++ G + E PGV++ ++ LP G + + P + +
Sbjct: 1173 ETAAPGVEDISGLPSGEVLETAAPGVED-ISGLPSGEVLETAAPGVEDISGLPSGEVLET 1231
Query: 1852 FSLNVE-YAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQT-SREIVIS 1909
+ VE + EV T +P VE S P+G VL T V E+I+ S E++ +
Sbjct: 1232 AAPGVEDISGLPSGEVLETAAPGVED-ISGLPSGEVLETAAPGV--EDISGLPSGEVLET 1288
Query: 1910 ERLGEPNYGAEIRGFSTGFPLEEDFSGDFREYSTVSHPIAKEETV--MMEGSGDAAFRDT 1967
G EI G +G LE G E S + E T + E SG +
Sbjct: 1289 TAPGVE----EISGLPSGEVLETTAPG-VDEISGLPSGEVLETTAPGVEEISGLPSGEVL 1343
Query: 1968 QTSPSTVPT-----------SVHISHISDSEG-PSSTMVSTSAFPWEEFTSSAEGSGEQL 2015
+TS S V + +S + D G PS +V TSA E+ S SGE L
Sbjct: 1344 ETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDV--SELPSGEGL 1401
Query: 2016 VTVSSSVVPV--LPSAVQKFSGTASSIID--------EGL----GEVGT 2050
T +S V + LPS + +AS D EGL EVGT
Sbjct: 1402 ETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGT 1450
Score = 38.1 bits (87), Expect = 0.15
Identities = 121/549 (22%), Positives = 188/549 (34%), Gaps = 117/549 (21%)
Query: 1683 EVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTAS-----T 1737
E+P ++ VS QPS DTS S T + G +G AS T
Sbjct: 1614 EIPG--LFGVSGQPSGF---------PDTSGETSGVTELSGLSSGQPGISGEASGVLYGT 1662
Query: 1738 FEVYSSTQRSDQLILPFELESPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTETN 1797
+ + T S + +L SG L + T S + F +T+
Sbjct: 1663 SQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGI-TFVDTS 1721
Query: 1798 TLENLGAQTTEHS---SIHQPGVQEGLTTLPRSPASVFME-QGSGEAAADPETTTVSSFS 1853
+E E S+ G+ G L V + Q SG + T+ FS
Sbjct: 1722 LVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFS 1781
Query: 1854 LN----VEYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQ--TSREIV 1907
E + ++ + G+ P S P+ +++DR + E++TQ T++E
Sbjct: 1782 GLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAG 1841
Query: 1908 -----ISERLGEPNYGAEIRGFSTGF-----------------PLEEDFSGDFREYSTVS 1945
I E G + ++ G +GF P FSGDF + VS
Sbjct: 1842 EGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVS 1901
Query: 1946 HPIAKEETVMMEGSGDAA-----------FRDTQTSPSTV------PTSVHISHISDSEG 1988
E +V M SG+A+ F + T P+ P H + +S G
Sbjct: 1902 G----ESSVAMGTSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSG 1957
Query: 1989 PSSTM------------------------VSTSAFPWEEFTSSA------EGSGEQLVTV 2018
ST TSA+P F +SA E SG ++
Sbjct: 1958 KVSTAGDISGATPVLPGSGVEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSE 2017
Query: 2019 SSSVVPVLPSAVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAP------ 2072
++S G + S + GE E+ ST T++V GT+AP
Sbjct: 2018 TTSAFHEANLERSSGLGVSGSTLTFQEGEASAAPEVSGESTT--TSDV-GTEAPGLPSAT 2074
Query: 2073 --VEKEEVKVSGTVSTNFPQ------TIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEK 2124
+ ++SG +S + Q T P W++Q P +E E++S EE
Sbjct: 2075 PTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESSSLLYSGEET 2134
Query: 2125 SFESPQNSP 2133
SP
Sbjct: 2135 HTVETATSP 2143
>gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]
Length = 2317
Score = 363 bits (932), Expect = 2e-99
Identities = 347/1210 (28%), Positives = 540/1210 (44%), Gaps = 168/1210 (13%)
Query: 7 SILWMCSTL-IVTHALH----------KVKVGKSPPVRGSLSGKVSLPCHF-STMPTLPP 54
++LW+ TL ++T A+ V + + P+R L +++PC+F M +
Sbjct: 3 TLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHPVTT 62
Query: 55 SYNTSEFL-RIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDA 113
+ +T+ RIKWS++ +K E +LVA G +++ Y+ +VS+P +P DA
Sbjct: 63 APSTAPLAPRIKWSRVSKEK------EVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDA 116
Query: 114 SLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACL 173
+L V L ++D+G+YRC+VM+GIED++ T+ + V G+VFHYRA ++RYTL+F+ AQ+ACL
Sbjct: 117 TLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACL 176
Query: 174 DVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFR 233
A+IATPEQL AAYEDGF QCDAGWLADQTVRYPI PR GCYGDK GVRTYG R
Sbjct: 177 QNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIR 236
Query: 234 SPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQ 293
ETYDVYC+ + ++G+VF+ T P KFTF+EAA EC ARLAT G+L AW+ G D
Sbjct: 237 DTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDM 296
Query: 294 CDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKPKEATT 353
C GWL+D SVR+P++ AR CGG LLGVRT+Y NQTG+P P SR+DA C+ ++
Sbjct: 297 CSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVD 356
Query: 354 I-----------DLSILAETASPSLSKEPQMVSD---RTTPIIPLVDELPVIPTEFPPVG 399
I D+++ T P+ +++ R + I+ + V P+ P
Sbjct: 357 IPENFFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPSPLEP-- 414
Query: 400 NIVSFEQKATVQPQAITDSLATKLPTPTGSTKKPWDMDDYSPSASGPLGKLDISEIKEEV 459
E+ T P+ + A ++ TG +PW + GP ++ +V
Sbjct: 415 -----EEPFTFAPEIGATAFA-EVENETGEATRPW---GFPTPGLGPATAFTSEDLVVQV 465
Query: 460 LQSTTGVSHYATDSWDGVV---EDKQTQESVT----QIEQIEVGPLVTSMEILKHIPSKE 512
+ G H GVV T+ S+T Q + G ++ S E L+
Sbjct: 466 -TAVPGQPHLP----GGVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAG 520
Query: 513 FPVTETPLVTARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLI 572
+ + A + + +VS + V G++D T G ST
Sbjct: 521 YEQCD-----AGWLRDQTVRYPIVSPRTPCV---------GDKDSSPGVRTYGVRPSTET 566
Query: 573 FDQI-------PEVITVSKTSEDTIHTHLEDLESVSAS-TTVSPLIMPDNNGSSMDDWEE 624
+D EV ++ + T LE ES +A+ T L + G +
Sbjct: 567 YDVYCFVDRLEGEVFFATRLEQFTFQEALEFCESHNATLATTGQLYAAWSRGL------D 620
Query: 625 RQTSGRITEEFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEGISTV-IYPSLQTEMTHR 683
+ +G + + L +Y TP P+ GDK G+ TV +YP+ QT +
Sbjct: 621 KCYAGWLADGSL-RYPIVTPRPA----------CGGDK---PGVRTVYLYPN-QTGLPDP 665
Query: 684 RERTETLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEM 743
R R + EE +P EE + + P+ ++V
Sbjct: 666 LSRHHAFC--FRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTAVPS 723
Query: 744 TKSFDFPTLITKLSAEPTEVRDMEEDFTAT-----PG--TTKYDENITTVLLAHGTLSVE 796
++ T I + + EP + E +T PG T T G + E
Sbjct: 724 GET----TAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSATE 779
Query: 797 AATVSKWSWDEDNTTSKPLESTEPSASSKLPPAL--LTTVGMNGKDKDIPSFTEDGADE- 853
+ S +E + + P S EPS S + P++ +V + ++ PS ++E
Sbjct: 780 VPSAS----EEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEP 835
Query: 854 ---------------FTLIPDSTQKQ-LEEVTDE-----DIAAHGKFTIRFQPTTSTGIA 892
+T +P S ++ +V+ + D++ H F+ + ++G+
Sbjct: 836 SASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLP 895
Query: 893 EKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVD--LSKPVSTVPQFAHTSE-- 948
DS+ +TST G G G+ E ++ + V +P A E
Sbjct: 896 SGDL--DSS------GLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGS 947
Query: 949 VEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVID 1008
G+ +S + E +S LS +P + VL + P +++ G PS ++L
Sbjct: 948 ASGVGDLSGLPSGE-VLETSASGVGDLSGLPSGE--VLETTAPGVEDISGLPSGEVL--- 1001
Query: 1009 QTRLEATISPETMRTTKITEGTTQE-EFPWKEQTAEKPVPALSSTAWTPKEAVTPLDEQE 1067
T +P + + G E P E + P + T E ++ L
Sbjct: 1002 -----ETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGL--PS 1054
Query: 1068 GDGSAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIG 1127
G+ T E ++G VLETT G D S P G V E E ++ P
Sbjct: 1055 GEVLETTAPGVEDISGLPSGEVLETTAPGVEDIS-GLPSGEVLETAAPGVEDISGLPSGE 1113
Query: 1128 PKVSLSPGPE 1137
+ +PG E
Sbjct: 1114 VLETAAPGVE 1123
Score = 209 bits (532), Expect = 4e-53
Identities = 86/129 (66%), Positives = 104/129 (80%)
Query: 3165 DTETCDYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQ 3224
D E C+ GW+K+QG CY++F R TW AER CR Q +HL+SI++ EEQ FVN DYQ
Sbjct: 2164 DQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQ 2223
Query: 3225 WIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYH 3284
WIGLND+ E DFRW+DG +Q+ENWRPNQPD+FF+AGEDCVV+IWHE G+WNDVPCNYH
Sbjct: 2224 WIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYH 2283
Query: 3285 LTYTCKKGT 3293
L +TCKKGT
Sbjct: 2284 LPFTCKKGT 2292
Score = 40.8 bits (94), Expect = 0.023
Identities = 179/769 (23%), Positives = 269/769 (34%), Gaps = 105/769 (13%)
Query: 1356 PCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKH 1415
P EET V + EF EN+ E E + P +
Sbjct: 713 PVEEETTAVPSGETTAILEFTT--------EPENQTEWEPAYTPVGTSPLPGI------- 757
Query: 1416 LVTTVPKDPEAAEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTETTE 1475
L T P E+ G + PS + S P E S + +P S
Sbjct: 758 LPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFP----SEEPSPSEEPFPSVRPFP 813
Query: 1476 SLEVTWKPETYPET----SEHFSGGEPDVFPT--VPFHEEFESGTAKKGAESVTERDTEV 1529
S+E+ E +P SE S E P+ VP E S + GA V+ T
Sbjct: 814 SVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGS 873
Query: 1530 GHQAHEHTEPVSLFPEESSGEIAIDQESQ----KIAFARATEVTFGEEVEKSTSVTYTPT 1585
G + L + +SG + D +S + E E+ TPT
Sbjct: 874 GDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPT 933
Query: 1586 I--VPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWV------------EATPRQVVELS 1631
+ +PS A V + ++L T S V E T V ++S
Sbjct: 934 VGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDIS 993
Query: 1632 GSSSIPITEGSGEAEEDE---------DTMFTMVTDLSQRNTTDTLITL-----DTSRII 1677
G S + E + ED +T V D+S + + L T D S +
Sbjct: 994 GLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLP 1053
Query: 1678 TESFFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTAST 1737
+ E A + +S PS +V+ T D S + S V E E +G S
Sbjct: 1054 SGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISG-LPSGEVLETAAPGVEDISGLPSG 1112
Query: 1738 FEVYSSTQRSDQLI-LP----FELESPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPV 1792
+ ++ + + LP E +P V S + + + + + +
Sbjct: 1113 EVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVL 1172
Query: 1793 FTETNTLENL-GAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSS 1851
T +E++ G + E PGV++ ++ LP G + + P + +
Sbjct: 1173 ETAAPGVEDISGLPSGEVLETAAPGVED-ISGLPSGEVLETAAPGVEDISGLPSGEVLET 1231
Query: 1852 FSLNVE-YAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQT-SREIVIS 1909
+ VE + EV T +P VE S P+G VL T V E+I+ S E++ +
Sbjct: 1232 AAPGVEDISGLPSGEVLETAAPGVED-ISGLPSGEVLETAAPGV--EDISGLPSGEVLET 1288
Query: 1910 ERLGEPNYGAEIRGFSTGFPLEEDFSGDFREYSTVSHPIAKEETV--MMEGSGDAAFRDT 1967
G EI G +G LE G E S + E T + E SG +
Sbjct: 1289 TAPGVE----EISGLPSGEVLETTAPG-VDEISGLPSGEVLETTAPGVEEISGLPSGEVL 1343
Query: 1968 QTSPSTVPT-----------SVHISHISDSEG-PSSTMVSTSAFPWEEFTSSAEGSGEQL 2015
+TS S V + +S + D G PS +V TSA E+ S SGE L
Sbjct: 1344 ETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDV--SELPSGEGL 1401
Query: 2016 VTVSSSVVPV--LPSAVQKFSGTASSIID--------EGL----GEVGT 2050
T +S V + LPS + +AS D EGL EVGT
Sbjct: 1402 ETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGT 1450
Score = 40.4 bits (93), Expect = 0.030
Identities = 132/616 (21%), Positives = 214/616 (34%), Gaps = 133/616 (21%)
Query: 1683 EVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTAS-----T 1737
E+P ++ VS QPS DTS S T + G +G AS T
Sbjct: 1614 EIPG--LFGVSGQPSGF---------PDTSGETSGVTELSGLSSGQPGISGEASGVLYGT 1662
Query: 1738 FEVYSSTQRSDQLILPFELESPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTETN 1797
+ + T S + +L SG L + T S + F +T+
Sbjct: 1663 SQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGI-TFVDTS 1721
Query: 1798 TLENLGAQTTEHS---SIHQPGVQEGLTTLPRSPASVFME-QGSGEAAADPETTTVSSFS 1853
+E E S+ G+ G L V + Q SG + T+ FS
Sbjct: 1722 LVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFS 1781
Query: 1854 LN----VEYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQ--TSREIV 1907
E + ++ + G+ P S P+ +++DR + E++TQ T++E
Sbjct: 1782 GLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAG 1841
Query: 1908 -----ISERLGEPNYGAEIRGFSTGF-----------------PLEEDFSGDFREYSTVS 1945
I E G + ++ G +GF P FSGDF + VS
Sbjct: 1842 EGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVS 1901
Query: 1946 HPIAKEETVMMEGSGDAA-----------FRDTQTSPSTV------PTSVHISHISDSEG 1988
E +V M SG+A+ F + T P+ P H + +S G
Sbjct: 1902 G----ESSVAMGTSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSG 1957
Query: 1989 PSSTM------------------------VSTSAFPWEEFTSSA------EGSGEQLVTV 2018
ST TSA+P F +SA E SG ++
Sbjct: 1958 KVSTAGDISGATPVLPGSGVEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSE 2017
Query: 2019 SSSVVPVLPSAVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAP------ 2072
++S G + S + GE E+ ST T++V GT+AP
Sbjct: 2018 TTSAFHEANLERSSGLGVSGSTLTFQEGEASAAPEVSGESTT--TSDV-GTEAPGLPSAT 2074
Query: 2073 --VEKEEVKVSGTVSTNFPQ------TIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEK 2124
+ ++SG +S + Q T P W++Q P +E E++S EE
Sbjct: 2075 PTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESSSLLYSGEET 2134
Query: 2125 SFESPQNSPA-------------TEQTIFDSQTFTE--TELKTTDYSVLTTKKTYSD-DK 2168
SP +E T D + E + + Y ++T+ D ++
Sbjct: 2135 HTVETATSPTDASIPASPEWKRESESTAADQEVCEEGWNKYQGHCYRHFPDRETWVDAER 2194
Query: 2169 EMKEEDTSLVNMSTPD 2184
+E+ + L ++ TP+
Sbjct: 2195 RCREQQSHLSSIVTPE 2210
>gi|38372931 brevican isoform 2 [Homo sapiens]
Length = 671
Score = 324 bits (830), Expect = 1e-87
Identities = 176/446 (39%), Positives = 251/446 (56%), Gaps = 24/446 (5%)
Query: 23 KVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSEFLRIKWSKIEVDKNGKDLKETT 82
+V++ P++G L G +++PCH + P R+KW+ + + E
Sbjct: 36 RVRIAGDAPLQGVLGGALTIPCHVHYLRPPPSRRAVLGSPRVKWTFLSRGR------EAE 89
Query: 83 VLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDT 142
VLVA+ +K+ + Y+ RV++P +P ++ D SL + +L +D+G+YRC+V +GI+D+ D
Sbjct: 90 VLVARGVRVKVNEAYRFRVALPAYPASLTDVSLALSELRPNDSGIYRCEVQHGIDDSSDA 149
Query: 143 VSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLA 202
V + V GVVF YR ++RY +F AQ+AC +GA IATPEQL+AAY G+EQCDAGWL+
Sbjct: 150 VEVKVKGVVFLYREGSARYAFSFSGAQEACARIGAHIATPEQLYAAYLGGYEQCDAGWLS 209
Query: 203 DQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYDVYCYVDHLDGDVFHLTVPSKFT 262
DQTVRYPI+ PR CYGD G GVR YG P + YDVYCY + L+G++F P K T
Sbjct: 210 DQTVRYPIQTPREACYGDMDGFPGVRNYGVVDPDDLYDVYCYAEDLNGELFLGDPPEKLT 269
Query: 263 FEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGV 322
EEA C+ + A +AT G+L AAW G D C GWL+D SVR+P+ +CGGGL GV
Sbjct: 270 LEEARAYCQERGAEIATTGQLYAAWDGGLDHCSPGWLADGSVRYPIVTPSQRCGGGLPGV 329
Query: 323 RTLYRFENQTGFPPPDSRFDAYCFKPKEATTIDLSILAETASPSLSKEPQMVSDRTTPII 382
+TL+ F NQTGFP SRF+ YCF+ + S + E ++P+ + SD I+
Sbjct: 330 KTLFLFPNQTGFPNKHSRFNVYCFR----DSAQPSAIPEASNPASNP----ASDGLEAIV 381
Query: 383 PLVD-----ELPVIPTEFPPVGNIVSFE-----QKATVQPQAITDSLATKLPTPTGSTKK 432
+ + +LP TE G I S + P+ ++ T L T S
Sbjct: 382 TVTETLEELQLPQEATESESRGAIYSIPIMEDGGGGSSTPEDPAEAPRTLLEFETQSMVP 441
Query: 433 PWDMDDYSPSASGPLGKLDISEIKEE 458
P + A K + E KEE
Sbjct: 442 PTGFSEEEGKALEEEEKYEDEEEKEE 467
>gi|38372935 brevican isoform 1 [Homo sapiens]
Length = 911
Score = 324 bits (830), Expect = 1e-87
Identities = 176/446 (39%), Positives = 251/446 (56%), Gaps = 24/446 (5%)
Query: 23 KVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSEFLRIKWSKIEVDKNGKDLKETT 82
+V++ P++G L G +++PCH + P R+KW+ + + E
Sbjct: 36 RVRIAGDAPLQGVLGGALTIPCHVHYLRPPPSRRAVLGSPRVKWTFLSRGR------EAE 89
Query: 83 VLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDT 142
VLVA+ +K+ + Y+ RV++P +P ++ D SL + +L +D+G+YRC+V +GI+D+ D
Sbjct: 90 VLVARGVRVKVNEAYRFRVALPAYPASLTDVSLALSELRPNDSGIYRCEVQHGIDDSSDA 149
Query: 143 VSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLA 202
V + V GVVF YR ++RY +F AQ+AC +GA IATPEQL+AAY G+EQCDAGWL+
Sbjct: 150 VEVKVKGVVFLYREGSARYAFSFSGAQEACARIGAHIATPEQLYAAYLGGYEQCDAGWLS 209
Query: 203 DQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYDVYCYVDHLDGDVFHLTVPSKFT 262
DQTVRYPI+ PR CYGD G GVR YG P + YDVYCY + L+G++F P K T
Sbjct: 210 DQTVRYPIQTPREACYGDMDGFPGVRNYGVVDPDDLYDVYCYAEDLNGELFLGDPPEKLT 269
Query: 263 FEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGV 322
EEA C+ + A +AT G+L AAW G D C GWL+D SVR+P+ +CGGGL GV
Sbjct: 270 LEEARAYCQERGAEIATTGQLYAAWDGGLDHCSPGWLADGSVRYPIVTPSQRCGGGLPGV 329
Query: 323 RTLYRFENQTGFPPPDSRFDAYCFKPKEATTIDLSILAETASPSLSKEPQMVSDRTTPII 382
+TL+ F NQTGFP SRF+ YCF+ + S + E ++P+ + SD I+
Sbjct: 330 KTLFLFPNQTGFPNKHSRFNVYCFR----DSAQPSAIPEASNPASNP----ASDGLEAIV 381
Query: 383 PLVD-----ELPVIPTEFPPVGNIVSFE-----QKATVQPQAITDSLATKLPTPTGSTKK 432
+ + +LP TE G I S + P+ ++ T L T S
Sbjct: 382 TVTETLEELQLPQEATESESRGAIYSIPIMEDGGGGSSTPEDPAEAPRTLLEFETQSMVP 441
Query: 433 PWDMDDYSPSASGPLGKLDISEIKEE 458
P + A K + E KEE
Sbjct: 442 PTGFSEEEGKALEEEEKYEDEEEKEE 467
Score = 300 bits (768), Expect = 2e-80
Identities = 186/557 (33%), Positives = 277/557 (49%), Gaps = 60/557 (10%)
Query: 2827 SPLTIYSGSEASGHTEIPQ---PSALPGIDVGSSVMSPQDSFKEIHVNIEATFKPSSEEY 2883
S +Y +++ + IP+ P++ P D ++++ ++ +E+ + EAT S
Sbjct: 346 SRFNVYCFRDSAQPSAIPEASNPASNPASDGLEAIVTVTETLEELQLPQEATESESRGAI 405
Query: 2884 --LHITEPPSLSPDTKLEPSEDDGKPELLEEMEA---------SPTELIAVEGTEILQDF 2932
+ I E T +P+E P L E E S E A+E E +D
Sbjct: 406 YSIPIMEDGGGGSSTPEDPAE---APRTLLEFETQSMVPPTGFSEEEGKALEEEEKYEDE 462
Query: 2933 QNKTDGQ----VSGEAIKMFPT-IKTPEAGTVITTADEIELEGATQWPHSTSASATYGVE 2987
+ K + + V EA+ +P+ + +P + T + E +Q P
Sbjct: 463 EEKEEEEEEEEVEDEALWAWPSELSSPGPEASLPTEPAAQEESLSQAP----------AR 512
Query: 2988 AGVVPWLSPQTSERPTLSSSPEINPETQAALIRGQDSTIAASEQQVAARILDSNDQATVN 3047
A + P SP S P ++ L ++ +A+ + + AT
Sbjct: 513 AVLQPGASPLPDGESEASRPPRVHGPPTETLPTPRERNLASPSPSTLVEAREVGE-ATGG 571
Query: 3048 PV----------EFNTEVATPPFSLLETSNETDFLIGINEESVEGTAIYLPGPDRCKMNP 3097
P E + P SLL + + + S + + P + P
Sbjct: 572 PELSGVPRGESEETGSSEGAP--SLLPATRAPEGTRELEAPSEDNSGRTAPAGTSVQAQP 629
Query: 3098 CLNGGTCYPTET-SYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPS 3156
L PT++ S V SGD C +PC NG TC++ RCLCLP
Sbjct: 630 VL------PTDSASRGGVAVVPASGD--------CVPSPCHNGGTCLEEEEGVRCLCLPG 675
Query: 3157 YVGALCEQDTETCDYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFV 3216
Y G LC+ C+ GW FQG CYK+F+ RR+W+ AE +CR+ GAHL SI + EEQ F+
Sbjct: 676 YGGDLCDVGLRFCNPGWDAFQGACYKHFSTRRSWEEAETQCRMYGAHLASISTPEEQDFI 735
Query: 3217 NRVGHDYQWIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQW 3276
N +YQWIGLND+ E DF W+DG L YENW P QPDS+F +GE+CVV++WH+ GQW
Sbjct: 736 NNRYREYQWIGLNDRTIEGDFLWSDGVPLLYENWNPGQPDSYFLSGENCVVMVWHDQGQW 795
Query: 3277 NDVPCNYHLTYTCKKGTVACGQPPVVENAKTFGKMKPRYEINSLIRYHCKDGFIQRHLPT 3336
+DVPCNYHL+YTCK G V+CG PP + A+ FG+ + RYE+++++RY C++G QR+LP
Sbjct: 796 SDVPCNYHLSYTCKMGLVSCGPPPELPLAQVFGRPRLRYEVDTVLRYRCREGLAQRNLPL 855
Query: 3337 IRCLGNGRWAIPKITCM 3353
IRC NGRW P+I+C+
Sbjct: 856 IRCQENGRWEAPQISCV 872
>gi|4503053 hyaluronan and proteoglycan link protein 1 [Homo
sapiens]
Length = 354
Score = 217 bits (553), Expect = 1e-55
Identities = 126/313 (40%), Positives = 182/313 (58%), Gaps = 19/313 (6%)
Query: 38 GKVSLPCHFSTMPTLPPSYNTSEFLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDY 97
G V+LPC F PT S +RIKW+K+ D LKE V V+ + K Y
Sbjct: 55 GNVTLPCKFYRDPTAFGS--GIHKIRIKWTKLTSDY----LKEVDVFVSMGYHKKTYGGY 108
Query: 98 KGRVSVPTHPEAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAA 157
+GRV + ++ DASL + L D G Y+C+V+ G+ED V+L + GVVF Y
Sbjct: 109 QGRVFLKGGSDS--DASLVITDLTLEDYGRYKCEVIEGLEDDTVVVALDLQGVVFPYFPR 166
Query: 158 TSRYTLNFEAAQKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGC 217
RY LNF AQ+ACLD AVIA+ +QL+ A+ G + C+AGWL+D +V+YPI PR C
Sbjct: 167 LGRYNLNFHEAQQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPC 226
Query: 218 YGDKMGKAGVRTYGFRSPQET-YDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDAR 276
G + GVR YGF ++ YDV+C+ + +G ++L P+K T++EA + C N A+
Sbjct: 227 -GGQNTVPGVRNYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQ 285
Query: 277 LATVGELQAAWR-NGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFP 335
+A VG++ AAW+ G+D+CD GWL+D SVR+P++ R +C VR + GFP
Sbjct: 286 IAKVGQIFAAWKILGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFV-------GFP 338
Query: 336 PPDSR-FDAYCFK 347
+ + YCF+
Sbjct: 339 DKKHKLYGVYCFR 351
>gi|30102948 hyaluronan and proteoglycan link protein 3 [Homo
sapiens]
Length = 360
Score = 216 bits (551), Expect = 2e-55
Identities = 129/311 (41%), Positives = 175/311 (56%), Gaps = 21/311 (6%)
Query: 40 VSLPCHFSTMPTLPPSYNTSEFLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKG 99
V LPC + P L + +R+KW K+ +NG K+ VLVA + DY+G
Sbjct: 66 VILPCRYRYEPALV----SPRRVRVKWWKLS--ENGAPEKD--VLVAIGLRHRSFGDYQG 117
Query: 100 RVSVPTHPEAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATS 159
RV + E D SL + L D G YRC+V+ G+ED V L + GVVF Y++
Sbjct: 118 RVHLRQDKEH--DVSLEIQDLRLEDYGRYRCEVIDGLEDESGLVELELRGVVFPYQSPNG 175
Query: 160 RYTLNFEAAQKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYG 219
RY NF Q+ C + AV+A+ EQLF A+E+G + C+AGWL D TV+YPI PR C G
Sbjct: 176 RYQFNFHEGQQVCAEQAAVVASFEQLFRAWEEGLDWCNAGWLQDATVQYPIMLPRQPCGG 235
Query: 220 DKMGKAGVRTYGFRSPQ-ETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLA 278
+ GVR+YG R + YDV+C+ L G V++L P K T EA + C+ DA +A
Sbjct: 236 PGLA-PGVRSYGPRHRRLHRYDVFCFATALKGRVYYLEHPEKLTLTEAREACQEDDATIA 294
Query: 279 TVGELQAAWR-NGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPP 337
VG+L AAW+ +G D+CD GWL+D SVR+PV CG GVR+ GFP P
Sbjct: 295 KVGQLFAAWKFHGLDRCDAGWLADGSVRYPVVHPHPNCGPPEPGVRSF-------GFPDP 347
Query: 338 DSR-FDAYCFK 347
SR + YC++
Sbjct: 348 QSRLYGVYCYR 358
>gi|11141887 brain link protein-1 [Homo sapiens]
Length = 340
Score = 194 bits (493), Expect = 1e-48
Identities = 115/310 (37%), Positives = 172/310 (55%), Gaps = 30/310 (9%)
Query: 41 SLPCHFSTMPTLPPSYNTSEFLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGR 100
+LPC + T PPSY +++WSK+E +L+ET +L+ + + GR
Sbjct: 54 TLPC---VLGTTPPSY------KVRWSKVEPG----ELRETLILITNGLHARGYGPLGGR 100
Query: 101 VSVPTHPEAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSR 160
+ DASL + + D G YRC+++ GIED ++L+++GVVF Y+ + R
Sbjct: 101 ARMRRGHRL--DASLVIAGVRLEDEGRYRCELINGIEDESVALTLSLEGVVFPYQPSRGR 158
Query: 161 YTLNFEAAQKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGD 220
Y N+ A++AC + +AT QL+ A+ +G + C+AGWL + +VRYP+ R C G
Sbjct: 159 YQFNYYEAKQACEEQDGRLATYSQLYQAWTEGLDWCNAGWLLEGSVRYPVLTARAPCGG- 217
Query: 221 KMGKAGVRTYGFRS-PQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLAT 279
G+ G+R+YG R ++ YD +C+ L G VF VP + T EA C + A +A
Sbjct: 218 -RGRPGIRSYGPRDRMRDRYDAFCFTSALAGQVFF--VPGRLTLSEAHAACRRRGAVVAK 274
Query: 280 VGELQAAWR-NGFDQCDYGWLSDASVRHPVTVARAQCGG-GLLGVRTLYRFENQTGFP-P 336
VG L AAW+ +G DQCD GWL+D SVR P+T R +CGG GVR+ GFP P
Sbjct: 275 VGHLYAAWKFSGLDQCDGGWLADGSVRFPITTPRPRCGGLPDPGVRSF-------GFPRP 327
Query: 337 PDSRFDAYCF 346
+ + YC+
Sbjct: 328 QQAAYGTYCY 337
>gi|30794472 hyaluronan and proteoglycan link protein 4 [Homo
sapiens]
Length = 402
Score = 191 bits (486), Expect = 8e-48
Identities = 119/322 (36%), Positives = 169/322 (52%), Gaps = 30/322 (9%)
Query: 38 GKVSLPCHFSTMPTLPPSYNTSEFLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDY 97
G + LPC + + + + +R+KW+K+ VD L T V VA + Y
Sbjct: 62 GTIVLPCRYH----YEAAAHGHDGVRLKWTKV-VDP----LAFTDVFVALGPQHRAFGSY 112
Query: 98 KGRVSVPTHPEAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAA 157
+GR + + GDASL + + D G Y C+V +ED V L ++GVVF Y
Sbjct: 113 RGRAEL--QGDGPGDASLVLRNVTLQDYGRYECEVTNELEDDAGMVKLDLEGVVFPYHPR 170
Query: 158 TSRYTLNFEAAQKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGC 217
RY L F AQ+AC + ++A+ EQL AA+ DG + C+AGWL D +V+YP+ PR C
Sbjct: 171 GGRYKLTFAEAQRACAEQDGILASAEQLHAAWRDGLDWCNAGWLRDGSVQYPVNRPREPC 230
Query: 218 YG-DKMGKA--------GVRTYGFR-SPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAA 267
G G A G+R YG+R + +E YD +C+ +L G VF L F AA
Sbjct: 231 GGLGGTGSAGGGGDANGGLRNYGYRHNAEERYDAFCFTSNLPGRVFFLKPLRPVPFSGAA 290
Query: 268 KECENQDARLATVGELQAAWR-NGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLY 326
+ C + A +A VG+L AAW+ D+C GWL+D S R+P+ RA+CGG GVR+L
Sbjct: 291 RACAARGAAVAKVGQLFAAWKLQLLDRCTAGWLADGSARYPIVNPRARCGGRRPGVRSL- 349
Query: 327 RFENQTGFPPPDSR-FDAYCFK 347
GFP R F YC++
Sbjct: 350 ------GFPDATRRLFGVYCYR 365
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 180 bits (457), Expect = 2e-44
Identities = 622/3000 (20%), Positives = 1030/3000 (34%), Gaps = 368/3000 (12%)
Query: 352 TTIDLSILAETASPSLSKEPQMVSDRTTPIIPL-VDELPVIPTEFPPVGNIVSFEQKATV 410
TT + + T S S S+ TTP+ + V PV+ +E + +S T
Sbjct: 1369 TTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSE----ASTLSATPVDTS 1424
Query: 411 QPQAITDSLATKLPTPTGSTKKPWDM--DDYSPSASGPLGKLDISEIKEEVLQSTTGVSH 468
P T + AT PT P + +P S P+ ++ + L +T
Sbjct: 1425 TP-GTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTP---- 1479
Query: 469 YATDSWDGVVEDKQTQESVTQIEQIEVGPLVTSMEILKHIPSKEFPVTETPLVTARMILE 528
DS VV S T E + + T E + S PV+ T + ++ +
Sbjct: 1480 --VDSNSPVVTSTAVSSSPTPAEGTSIA-ISTPSEGSTALTS--IPVSTTTVASSEINSL 1534
Query: 529 SKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVITVSKTSED 588
S T + V+ T + T + GS T + + ++ VS +
Sbjct: 1535 STTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSL--PVSTMLVVSSEANT 1592
Query: 589 TIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGKYLSTTPFPSQ 648
T ++ V+AST S + GSSM + S +T +STTP S
Sbjct: 1593 LSTTPIDSKTQVTASTEASSSTTAE--GSSMTISTPSEGSPLLTSI----PVSTTPVASP 1646
Query: 649 HRTEIELFPYSGDKILVEG--ISTVIYPSLQTEM---THRRERTETLIPEMRTDTYTDEI 703
+ + P + ++ +S+ P+ T M T+ RT +RT
Sbjct: 1647 EASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSA 1706
Query: 704 QEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTES--SVEMTKSFDFPTLITKLSAEPT 761
++ +P T + + S + SE + S S T P T + +
Sbjct: 1707 ISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEA 1766
Query: 762 EVRDMEEDFTATPGTTKYDE----------NITTVLLAHGTLSVEAATVSKW---SWDED 808
T+TP TT + +I T L+ G + + VS + +
Sbjct: 1767 STLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEAS 1826
Query: 809 NTTSKPLESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDST----QKQ 864
++ P++S P +S + T PS +G+ T IP ST +
Sbjct: 1827 TLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPS---EGSTALTSIPVSTTTVASSE 1883
Query: 865 LEEVTDEDIAAHGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSA 924
++ T Q ++S A+ S++ ST E PP+TS T+ S
Sbjct: 1884 TNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVST-TTVASSE 1942
Query: 925 LGEVEDV--DLSKPVSTVPQFAH---TSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIP 979
+ + D PV+T Q + T++ + +YS P T + S T+ +S
Sbjct: 1943 INTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVS--- 1999
Query: 980 KTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEATISPETMRTTKITEGTTQEEFPWKE 1039
SE L D T E + SP T T I T E
Sbjct: 2000 ------------SEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSER---TT 2044
Query: 1040 QTAEKPVPA----------LSSTAWTPKEAVTPLDEQEG----DGSAYTVSEDELLTGSE 1085
A PV LS+T K VT E +GS+ T+S SE
Sbjct: 2045 PLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAP-----SE 2099
Query: 1086 RVPVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRI-GPKVSLSPGPEQKYETEG 1144
P+L + P+ + P + + T V + +P I +VS SP P + +
Sbjct: 2100 GSPLLTSIPLS------TTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQT 2153
Query: 1145 SSTTGFTSSLS--PFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATELIEFSTIKVT 1202
S+ + + L+ P ST + +T T ++ + E + E +++ +
Sbjct: 2154 STYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTS 2213
Query: 1203 VPSDITTAFSSVDRLHTTSAFKPSSAITKKPPLIDREP--------GEETTSDMVIIGES 1254
PS+ +T F+S+ + T ++ P+ P TT++ I S
Sbjct: 2214 TPSEGSTPFTSMP-VSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTS 2272
Query: 1255 TSHVPPTTLEDIVAKET-----------ETDIDREY-FTTSS-----PPATQPTRPPTVE 1297
T T L I T T +D FTTS+ PP + T PT
Sbjct: 2273 TLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTST 2332
Query: 1298 DKEAFGPQALSTPQPPASTKFHPDINVYIIEVRENKTGR-MSDLSVIGHPIDSESKEDEP 1356
E P + P ST + T ++ S G + P
Sbjct: 2333 SSEGNTPLT----RMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMP 2388
Query: 1357 CSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKHL 1416
S ++ L + + P + HS + +T+ +++P+ G +
Sbjct: 2389 TSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTA--EGTSI 2446
Query: 1417 VTTVPKDPE--------------AAEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELS 1462
T+ P + ++EA V S + S+E+ + P +
Sbjct: 2447 PTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVP 2506
Query: 1463 TAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESV 1522
+ ST T S+ V+ P PE S + P V E S T+ +G
Sbjct: 2507 ISTASEGSTLLT-SIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMP 2565
Query: 1523 TERDTEVGHQAHEHTEPVSLFPEESS--GEIAIDQESQKIAFARATEVTFGEEVEKSTSV 1580
T +E + PVS P SS ++ I +TE + K TS+
Sbjct: 2566 TSTYSEGSTPLR--SMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSM 2623
Query: 1581 TY-TPTIVPSSASAY------VSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGS 1633
TP+ V +S ++ V+ EA TL P L T + ++P GS
Sbjct: 2624 PISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTA---EGS 2680
Query: 1634 SSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIYPVS 1693
S T G + T + S+ +T T +DTS +T S + P +
Sbjct: 2681 SMPTSTPGERSTPLTNILVSTTLLANSEASTLSTT-PVDTSTPVTTS----AEASSSPTT 2735
Query: 1694 EQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILP 1753
+ ++ + T T + + ST TT ++ V +ST+ S P
Sbjct: 2736 AEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSS---P 2792
Query: 1754 FELESPNVATSSDSGTRKSFMSL----TTPTQSEREMTDSTPVFTET----NTLENLGAQ 1805
E ++ TS+ S T S+ T SE +TPV T T +T +
Sbjct: 2793 TTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPT 2852
Query: 1806 TTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKE 1865
T E + EG T L P S A E +T+S+ ++ + E
Sbjct: 2853 TAEGIVVPISTASEGSTLLTSIPVST-------TPVASSEASTLSTTPVDTSIPVTTSTE 2905
Query: 1866 VAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFS 1925
G+ SP + E T + +ST + ++ I++S P G+E S
Sbjct: 2906 --GSSSPT-----TAEGTSMPISTPSE------VSTPLTSILVST---VPVAGSEASTLS 2949
Query: 1926 TGFPLEEDFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVPT-SVHISHIS 1984
T P++ ++ S A+ ++ + G+ T S ST+P S S +S
Sbjct: 2950 TT-PVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLS 3008
Query: 1985 DSEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQKFSGTASSIIDEG 2044
+ +ST V+TS T+ AEG+G + T S P+ V S
Sbjct: 3009 RTPADTSTPVTTSTEASSSPTT-AEGTGIPISTPSEGSTPLTSIPV--------STTPVA 3059
Query: 2045 LGEVGTVNE--IDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQTIEPAKLWSRQE 2102
+ E T++ +D S ++ + EV + P E + +S + P T P S
Sbjct: 3060 IPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPV---STTP 3116
Query: 2103 VNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTETELKTTDYSVLTTKK 2162
V S T + S E+ + +E T + T +E T V T
Sbjct: 3117 VTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLV 3176
Query: 2163 TYSDDKEMKEE--DTSLVNMSTPDPDANGLESYTTLPEATEKSHFFLATALVTESIPAEH 2220
S+D + DTS ++ + ++ T++P +T T++ + P
Sbjct: 3177 VSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVAS 3236
Query: 2221 ----VVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLP--TESVNFT 2274
+++ +P+ + T + S G L ++P T +V +
Sbjct: 3237 SEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASS 3296
Query: 2275 EVEQIN----NTLYPHTSQVESTSSDKIEDFNRMENVAKEVG--PLVSQTDIFEGSGSVT 2328
E ++ +T P T+ +++SS I D M G PL + S +
Sbjct: 3297 ETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNM--------SFS 3348
Query: 2329 STTLIEILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSNKNSST 2388
+T ++ + T + P P +T + T I TS P T ++ ST
Sbjct: 3349 TTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVST 3408
Query: 2389 AEI--NETTTSSTDFLARAYGFEMAKEFVTSAPKPSDLYYEPSGEGSGEVDIVDSFHTSA 2446
+ +E T ST P S+ S E S I + TS
Sbjct: 3409 TPVVSSEVNTLST------------------TPVDSNTLVTTSTEASSSPTIAEG--TSL 3448
Query: 2447 TTQATRQESSTTFVSDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSEQNKSSPDPTSTL 2506
T T + S T +S L P V S++A T P + S SSP T
Sbjct: 3449 PTSTTSEGS--TPLSIMPLSTTP-VASSEASTLSTTPVDTSTPVTTSSPTNSSP----TT 3501
Query: 2507 SNTVSYERSTDGSFQDRFREFEDSTLKPNRKKPT--------ENIIIDLDKEDKDLILTI 2558
+ S ST G ST + + N + + T+
Sbjct: 3502 AEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATL 3561
Query: 2559 TESTILEILPELTSDKNTIIDIDHTKPVYEDILGMQTDIDTEVPSEPHDSNDESNDDSTQ 2618
+T+ P S T + + T T + PS P STQ
Sbjct: 3562 QVTTMRMSTPSEGSSSLTTMLLSST---------YVTSSEASTPSTPSVDRSTPVTTSTQ 3612
Query: 2619 VQEIYEAAVNLSLTEETFEGSADVLASYTQATHDESMTYEDRSQLDHMGFHFTTGIPAPS 2678
++L T + L +T S+T + + +T + S
Sbjct: 3613 SNSTPTPPEVITLPMSTPSEVSTPLTIMPVST--TSVTISEAGTASTLPVDTSTPV-ITS 3669
Query: 2679 TETELDVLLPTATSLPI--PRKSATVIPEIEGIKAEAKALDDMFESSTLSDGQAIADQSE 2736
T+ + P T++PI P + +T + + + E STLS +
Sbjct: 3670 TQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSS----EGSTLSTPSVVTST-- 3723
Query: 2737 IIPTLGQFERTQEEYE-DKKHAGPSFQPEFSSGAEEALVDHTPYLSIATTHLMDQSVTEV 2795
P E D S E S+ LV TP T + S +
Sbjct: 3724 --PVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTP-----VTRFPESSTPSI 3776
Query: 2796 PDVM---------EGSNPPYYTD--TTLAVSTFAKLSSQTPS---SPLTIYSGSEASGHT 2841
P V EGS+ P + TT+ +ST ++ S+ + SP+++ S SEAS +
Sbjct: 3777 PSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLS 3836
Query: 2842 EIPQPSALP---GIDVGSSVMSPQDSFKEIHVNIE----------ATFKPSSEEYLHITE 2888
P ++ P GS + + + I + E +T P+S I
Sbjct: 3837 TPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIAS 3896
Query: 2889 PPSLSPDTKLEPSEDDGKPELLEEMEASPTELIAVEGTEILQDFQNKTDGQVSGEAIKMF 2948
P L T PS D + +I T F T V+ +F
Sbjct: 3897 TPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTP--VTSSTADVF 3954
Query: 2949 PTIKTPEAGTVITTADEIELEGATQWPHSTSASATYGVEAGVVPWLSPQTSERPTLSSSP 3008
P T T + T+ E+ + +TS S T + +P T T+S++P
Sbjct: 3955 PAT-TGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYV--TMSTAP 4011
Query: 3009 EINPETQAALIRGQDSTIAASEQ-----QVAARILDSNDQATVNPVEFNTEVATPPFSLL 3063
P T + ST++A+ V R + + +++ P + P F
Sbjct: 4012 S-TPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESS-RPSTITSHTIPPTFPPA 4069
Query: 3064 ETSNETDFLIG---INEESVEGTAIYLPGPDRCKMNPCLNGGTCYPTETSYVCT-----C 3115
+S +N E+V R P + T PT T+
Sbjct: 4070 HSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTT-TAVPTNTTIKSNPTSTPT 4128
Query: 3116 VPGYS---GDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPSYVGALCEQDTETCDYG 3172
VP + GD C+ ++ C+NG T ++ +C C Y G LCE+ + D G
Sbjct: 4129 VPRTTTCFGDGCQNT-----ASRCKNGGT----WDGLKCQCPNLYYGELCEEVVSSIDIG 4179
Score = 160 bits (405), Expect = 2e-38
Identities = 612/2883 (21%), Positives = 980/2883 (33%), Gaps = 437/2883 (15%)
Query: 350 EATTIDLSILAETASPSLSKE----PQMVSDRTTPIIPLVDELPVIPTEFPPVGNIVSFE 405
E T+I S E ++P S P S+ +T I VD ++ T P
Sbjct: 320 EGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEP-------- 371
Query: 406 QKATVQPQAITDSLATKLPTPTGSTKKPWDMDDYSPSASGPLGKLDISEIKEEVLQSTTG 465
+ LPT +T + S PL + +S I +++T
Sbjct: 372 ---------------SSLPTTAEATSM---LTSTLSEGSTPLTNMPVSTILVASSEAST- 412
Query: 466 VSHYATDSWDGVVEDKQTQESVTQIEQIEVGPLVTSMEILKHIPSKEFPVTETPLVTARM 525
S DS V + S T E + TS P PV+ TP+ ++
Sbjct: 413 TSTIPVDSKTFVTTASEASSSPTTAEDTSIA---TSTPSEGSTPLTSMPVSTTPVASSEA 469
Query: 526 I------LESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEV 579
++SKT+ + S T E T ST+ E
Sbjct: 470 SNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVAS-SEA 528
Query: 580 ITVSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSS-MDDWEERQTSGRITEEFLGK 638
T+S T DT E+ S+STT +P + S S R+
Sbjct: 529 STLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEAS 588
Query: 639 YLSTTPFPSQH--RTEIELFPYSGDKILVEGIS--TVIYPSLQTEMTHRRERTETLIPEM 694
STTP S T E S EG S T Y T +T T TL+
Sbjct: 589 TTSTTPADSNTFVTTSSEA---SSSSTTAEGTSMPTSTYSERGTTITSMSVST-TLVASS 644
Query: 695 RTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMTKSFDFPTLIT 754
T + + T P TE S TS+ + TE S +T TL+
Sbjct: 645 EASTLSTTPVDSNT--PVTTSTEATSSSTTAEGTSMPTSTY-TEGSTPLTSMPVNTTLVA 701
Query: 755 KLSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKP 814
A ++ T+TP TT + + ++ A G S+ +T S+ S TS P
Sbjct: 702 SSEASTLSTTPVD---TSTPVTTSTEAS-SSPTTADGA-SMPTSTPSEGSTP---LTSMP 753
Query: 815 -----LESTEPSASSKLPPALLTTVGMNGKDKDIPSFTE----------DGADEFTLIPD 859
L S+E S S P T + + + P+ TE +G+ T IP
Sbjct: 754 VSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPV 813
Query: 860 S----TQKQLEEVTDEDIAAHGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITS--TE 913
S T + ++ + ++ T + ++S AE +++ ST E P+TS
Sbjct: 814 SITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVS 873
Query: 914 GQVYATMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTI 973
+ AT S L VD S PV T+ E + + S T +
Sbjct: 874 TTLVATSAISTLSTTP-VDTSTPV--------TNSTEARSSPTTSEGTSMPTSTPGEGST 924
Query: 974 PLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEATISPETMRTTKITEGTTQE 1033
PL+ +P + P V SE L D T EAT SP T T I T
Sbjct: 925 PLTSMPDST----TPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTST--- 977
Query: 1034 EFPWKEQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETT 1093
P E TPL + SE L+ + PV T
Sbjct: 978 ----------------------PSEGTTPLTSTPVSHTLVANSEASTLSTT---PVDSNT 1012
Query: 1094 PVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGP----KVSLSPGPEQKYETEGSSTTG 1149
P+ + S PP A + + T TP G ++ +S ET STT
Sbjct: 1013 PLTTSTEASSPPPTA------EGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTP 1066
Query: 1150 FTSSLSPFSTHITQLMEETTTEKTSLEDIDLGSG---LFEKPKATELIEFSTIKVTVPSD 1206
+S +P +T+ TT + TS+ G L P +T L+ S +
Sbjct: 1067 ADTS-TPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTP 1125
Query: 1207 ITTAFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDI 1266
+ T+ TTS SS T + I P E T+ + + ST+ V + +
Sbjct: 1126 VDTSIPV-----TTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTL 1180
Query: 1267 VAK--ETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGP-QALSTPQPPASTKFHPDIN 1323
+++T + +S PP + T PT E P ++ P ++ ++
Sbjct: 1181 STTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLS 1240
Query: 1324 VYIIE----VRENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDII 1379
++ V + S + G + + + + + PV + PE ++
Sbjct: 1241 TSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTS-PEASTLL 1299
Query: 1380 E--IDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESV 1437
+D E + T+ P+ Y G+ +T++P + + S
Sbjct: 1300 TTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILST 1359
Query: 1438 APSQN---FSDSSESDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFS 1494
P N + S+E+ + P T + + P+E T S+ V+ P E S +
Sbjct: 1360 TPVDNSTPVTTSTEACSSPTTSEGTSMPNS-NPSEGTTPLTSIPVSTTPVVSSEASTLSA 1418
Query: 1495 GGEPDVFPTVPFHEEFESGTAKKGAESVTERDTE---------VGHQ--AHEHTEPVSLF 1543
P E S T +G T +E V + A+ +S
Sbjct: 1419 TPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTT 1478
Query: 1544 PEESSGEIAIDQE-SQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVT 1602
P +S+ + S A T + E ST++T P + AS+ ++ +
Sbjct: 1479 PVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEIN-----S 1533
Query: 1603 LIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDTMFTMVTDLSQR 1662
L P T S ++P G+S T G + TM+ S+
Sbjct: 1534 LSTTPAVTSTPVTTYSQASSSPTTA---DGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEA 1590
Query: 1663 NTTDTLITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEE 1722
NT T +D+ +T S +TT +E S + S TS +S+T V
Sbjct: 1591 NTLSTT-PIDSKTQVTASTEASSSTT----AEGSSMTISTPSEGSPLLTSIPVSTTPVAS 1645
Query: 1723 KKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELESPNVATSSDSGTRKSFMSLT---TP 1779
+ TT S V +ST+ S P E ++ TS+ + R S+T TP
Sbjct: 1646 PEASTLS-TTPVDSNSPVITSTEVSSS---PTPAEGTSMPTSTYTEGRTPLTSITVRTTP 1701
Query: 1780 -------TQSEREMTDSTPVFTETNTLENLGAQTTEHSSIHQPGVQEG---LTTLPRSPA 1829
T S + +STPV T T + T+E +S+ EG LT++P S
Sbjct: 1702 VASSAISTLSTTPVDNSTPVTTSTEARSS--PTTSEGTSMPNSTPSEGTTPLTSIPVSTT 1759
Query: 1830 SVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEVAGTLSPHVETTFSTEPTGLVLST 1889
V + S +A +T+T + S A + GT P +T S T L +
Sbjct: 1760 PVLSSEASTLSATPIDTSTPVTTSTE---ATSSPTTAEGTSIP--TSTLSEGMTPLTSTP 1814
Query: 1890 VMDRVVAENITQT--------SREIVISERLGEPNYGAEIRGFSTGFPLEEDF------- 1934
V +VA + T + +V S + AE +T P E
Sbjct: 1815 VSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPV 1874
Query: 1935 ------SGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVP-------TSVHIS 1981
S + ST + T + S D + P++ P TS+ +S
Sbjct: 1875 STTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVS 1934
Query: 1982 HISDSEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSV-VPVLPSAVQKFSGTASSI 2040
+ + +T+ +T A T+ ++ S +S+ P + S
Sbjct: 1935 TTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLST 1994
Query: 2041 IDEGLGEVGTVNEIDRRSTILPTAEVEG-------------TKAPVEKEEVKVSGTVSTN 2087
E T++ ++ T EG T P E+ VST
Sbjct: 1995 TLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTT 2054
Query: 2088 FPQTIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTE 2147
+ E L S V+ Q S S E S ++P+ + S +
Sbjct: 2055 LVVSSEGNTL-STTPVDSKTQVTNSTEASSSATAEGSSMTI--SAPSEGSPLLTSIPLST 2111
Query: 2148 TELKTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDP-DANGLESYTTLPEATEKSHFF 2206
T + + + S L+T S+ + + S S+P P + +++ T T +
Sbjct: 2112 TPVASPEASTLSTTPVDSNSPVITSTEVS----SSPIPTEGTSMQTSTYSDRRTPLTSMP 2167
Query: 2207 LATALVTES----IPAEHVVTDSPIKKEESTKHFPKGMR----PTIQESDTELLFSGLGS 2258
++T +V S + V T +P+ + P PT S+ F+ +
Sbjct: 2168 VSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPV 2227
Query: 2259 GEEVLPTLPTESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQT 2318
+ T +++ T V+ T P T+ E+TSS + G + +
Sbjct: 2228 STMPVVTSEASTLSATPVD----TSTPVTTSTEATSSPTTAE-----------GTSIPTS 2272
Query: 2319 DIFEGSGSVTSTTLIEILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTIT 2378
+ EG+ +TS + L VA ST P + + + S P
Sbjct: 2273 TLSEGTTPLTSIPVSHTL---------VANSEVSTLSTTPVDSNTPFTTSTEASSPPPTA 2323
Query: 2379 EQDSNKNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPSDLY-YEPSGEGSGEVD 2437
E S S+++E N T FE + T A + + Y +G D
Sbjct: 2324 EGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTAD 2383
Query: 2438 IVDSFHTSATTQATRQESSTTFVSDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSEQNK 2497
TS T +T E ST S V P VS HS
Sbjct: 2384 -----DTSMPT-STYSEGSTPLTS---------------VPVSTMPVVSSEASTHS---- 2418
Query: 2498 SSPDPTSTLSNTVSYERSTDGSFQDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDLILT 2557
++P TST T ST+ S E P P+E T
Sbjct: 2419 TTPVDTSTPVTT-----STEASSSPTTAEGTSIPTSP----PSEGT-------------T 2456
Query: 2558 ITESTILEILPELTSDKNTIIDIDHTKPVYEDILGMQTDIDTEVPSEPHDSNDESNDDST 2617
S + P ++S+ T+ T +DT S P ++ E++ T
Sbjct: 2457 PLASMPVSTTPVVSSEAGTL---------------STTPVDT---STPMTTSTEASSSPT 2498
Query: 2618 QVQEIYEAAVNLSLTEETFEGSADVLASYTQATHDESMTYEDRSQLDHMGFHFTTGIPAP 2677
++I V +S E + S T E+ T + +T I +
Sbjct: 2499 TAEDI---VVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSS 2555
Query: 2678 STETELDVLLPTATSLPIPRKSATVIPEIEGIKAEAKALDDMFESSTLSDGQAIADQSEI 2737
+T E TS+P S P + + K L E+STLS D S
Sbjct: 2556 ATSAE-------GTSMPTSTYSEGSTP-LRSMPVSTKPLASS-EASTLSTTPV--DTS-- 2602
Query: 2738 IPTLGQFERTQEEYEDKKHAGPSFQP-EFSSGAEEALVDHTPYLSIATTHLMDQSV---- 2792
IP E + K + P P E S+ LV P S + L V
Sbjct: 2603 IPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRT 2662
Query: 2793 --------TEVPDVMEGSNPPYYT-------------DTTLAVSTFAKLSSQTP---SSP 2828
+ P EGS+ P T TTL ++ A S TP S+P
Sbjct: 2663 LVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTP 2722
Query: 2829 LTIYSGSEASGHTEIPQPSALPGIDVGSSVMSPQDSFKEIHVNIEATFKPSSEEYLHITE 2888
+T + +EAS P+ G + + +P D + + +T +S E ++
Sbjct: 2723 VT--TSAEASS-----SPTTAEGTSM--RISTPSDGSTPLTSILVSTLPVASSEASTVS- 2772
Query: 2889 PPSLSPDTKLEPSEDDGKPELLEEMEASPTELIAVEGTEILQDFQNKTDGQVSGEAIKMF 2948
+ + DT + + E +SPT T + T + S M
Sbjct: 2773 --TTAVDTSIPVTTST-------EASSSPT-------TAEVTSMPTSTPSETSTPLTSM- 2815
Query: 2949 PTIKTPEAGTVITTADEIELEGATQWPHSTSASATYGVEAGVVPWLSPQTSERPTLSSSP 3008
P TP A + T ++ +T ST AS++ G+V +S SE TL +S
Sbjct: 2816 PVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPIS-TASEGSTLLTS- 2873
Query: 3009 EINPETQAALIRGQDSTIAASEQQVAARILDSND--------QATVNPVEFNTEVATPPF 3060
P + + + ST++ + + + S + + T P+ +EV+TP
Sbjct: 2874 --IPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLT 2931
Query: 3061 SLL 3063
S+L
Sbjct: 2932 SIL 2934
Score = 158 bits (399), Expect = 1e-37
Identities = 622/2960 (21%), Positives = 1017/2960 (34%), Gaps = 412/2960 (13%)
Query: 348 PKEATTIDLSILAETASPSLSKEPQMV----SDRTTPIIPL-VDELPVIPTEFP-----P 397
P ++ T + ++SP+ +++ + S+ +TP+ + V PV +E P
Sbjct: 417 PVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTP 476
Query: 398 VGN---IVSFEQKATVQPQAITDSLATKLPTPTGSTKKPWDMDDYSPSASGPLGKLDISE 454
V + + + + ++ P A +S+ T P+ GST P AS L +
Sbjct: 477 VDSKTQVTTSTEASSSPPTAEVNSMPTSTPSE-GSTPLTSMSVSTMPVASSEASTLSTTP 535
Query: 455 IKEEVLQSTTGVSHYATDSWDGVVEDKQTQESVTQIEQIEVGPLVTSMEILKHIPSKEFP 514
+ +T+ + ++ + +G T + PL + + S E
Sbjct: 536 VDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGST-------PLTNMPVSTRLVVSSEAS 588
Query: 515 VTETPLVTARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFD 574
T T + + + +E ST +E G ++ +R T+ S +
Sbjct: 589 TTSTTPADSNTFVTTSSEASSSSTTAE-------GTSMPTSTYSERGTTITSMSVSTTLV 641
Query: 575 QIPEVITVSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEE 634
E T+S T D+ E+ S+STT MP S+ + TS +
Sbjct: 642 ASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPT---STYTEGSTPLTSMPVNTT 698
Query: 635 FL----GKYLSTTPF----PSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRER 686
+ LSTTP P TE P + D S+ T
Sbjct: 699 LVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADG-----------ASMPTSTPSEGST 747
Query: 687 TETLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMTKS 746
T +P +T T ++ +P T + + + S S P +S+ ++
Sbjct: 748 PLTSMPVSKT-LLTSSEASTLSTTPL--DTSTHITTSTEASCS---PTTTEGTSMPISTP 801
Query: 747 FDFPTLITKLSAEPTEVRDMEEDFTATPGTTKYDEN---ITTVLLAHGTLSVEAATVSKW 803
+ L+T + T V E +T TT D N T+ ++ E ++
Sbjct: 802 SEGSPLLTSIPVSITPVTSPE---ASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTS 858
Query: 804 SWDEDNT--TSKPLESTEPSAS-----SKLPPALLTTVGMNGKDKDIPSFTE-------- 848
++ E T TS P+ +T + S S P T V + + + P+ +E
Sbjct: 859 TYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTST 918
Query: 849 --DGADEFTLIPDST----QKQLEEVTDEDIAAHGKFTIRFQPTTSTGIAEKSTLRDSTT 902
+G+ T +PDST + ++ + T + T+S AE +++ ST
Sbjct: 919 PGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTP 978
Query: 903 EEKVPPITST--EGQVYATMEGSALGEVEDVDLSKPVSTVPQFAH---TSEVEGLAFVSY 957
E P+TST + A E S L VD + P++T + + T+E + +
Sbjct: 979 SEGTTPLTSTPVSHTLVANSEASTL-STTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTP 1037
Query: 958 SSTQEP-------TTYVDSSHTIPLSVIPK------TDWGVLVPSVPSED------EVLG 998
S P TT V SS T LS P T + S + D
Sbjct: 1038 SEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYS 1097
Query: 999 EPSQDILVID-QTRLEATISPETMRTTKITEG---TTQEEFPWKEQTAEKPVPALSSTAW 1054
E S + + TRL + T+ TT + TT E TAE S
Sbjct: 1098 EGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAE----GTSIPTS 1153
Query: 1055 TPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHKV 1114
P E TPL + SE L+ PV T V + S PP A
Sbjct: 1154 PPSEGTTPLASMPVSTTLVVSSEANTLS---TTPVDSKTQVATSTEASSPPPTAEVTSMP 1210
Query: 1115 KTDEVVTLTPRIGPKVSLSPGPEQKYETEGSS--------TTGFTSSLSPFSTHITQLME 1166
+ TP V +P + T +S TT +S SP + T L
Sbjct: 1211 TSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPT 1270
Query: 1167 ETTTE-KTSLEDIDLGSGLFEKPKATELI-----------------------EFSTIKVT 1202
TT+E T L I + + L P+A+ L+ E +++ +
Sbjct: 1271 STTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTS 1330
Query: 1203 VPSDITTAFSSVDRLHTTSAFKPSSAITKKPPLIDREP--------GEETTSDMVIIGES 1254
S+ T +S+ ++TT + +I P+ + P TTS+ + S
Sbjct: 1331 TYSEGRTPLTSIP-VNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNS 1389
Query: 1255 TSHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPA 1314
T L I T + E T S+ P T P T + P P
Sbjct: 1390 NPSEGTTPLTSIPVSTTPV-VSSEASTLSATPVDTST-PGTTSAEATSSPTTAEGISIPT 1447
Query: 1315 STKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMAEILPE 1374
ST + I V ++ P+DS S + + P I
Sbjct: 1448 STPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAIS 1507
Query: 1375 FPD-----IIEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVTTVP-KDPEAAE 1428
P + I + + E + VT+TP Y TT + +
Sbjct: 1508 TPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTST 1567
Query: 1429 ARRGQ--FESVAPSQNFSDSSES--------DTHPFVIAKTELS----------TAVQPN 1468
G S+ S SSE+ D+ V A TE S T P+
Sbjct: 1568 YSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPS 1627
Query: 1469 ESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTE 1528
E + S+ V+ P PE S + P + E S T +G T TE
Sbjct: 1628 EGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTE 1687
Query: 1529 VGHQAHE---HTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPT 1585
T PV+ + +D +T VT E S + + +
Sbjct: 1688 GRTPLTSITVRTTPVASSAISTLSTTPVD---------NSTPVTTSTEARSSPTTSEGTS 1738
Query: 1586 IVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATP----RQVVELSGSSSIPIT-E 1640
+ S+ S + ++ + P +LS++ S + ATP V + ++S P T E
Sbjct: 1739 MPNSTPSEGTTPLTSIPVSTTP----VLSSEASTLSATPIDTSTPVTTSTEATSSPTTAE 1794
Query: 1641 GSGEAEEDEDTMFTMVTDLSQRNTTDTLI------TLDTSRIITESFFEVPATTIYPVSE 1694
G+ T+ +T L+ + TL+ TL T+ + + S P T VS
Sbjct: 1795 GT---SIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNS----PVVTSTAVSS 1847
Query: 1695 QPS---AKVVPTKFVSETD---TSEWISSTTVEEKKRKEEEGTTGTAST-FEVYSSTQRS 1747
P+ + T SE TS +S+TTV + T ST Y+ S
Sbjct: 1848 SPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSS 1907
Query: 1748 DQLILPFELESPNVATSSDSGTRKSFMSL--TTPTQSEREMTDSTPVFTETNTLENLGAQ 1805
P + ++ TS+ R S+ +T T + E+ + +T T +Q
Sbjct: 1908 -----PTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQ 1962
Query: 1806 ------TTEHSSIHQPGVQEG---LTTLPRSPASVFMEQGSGEAAADPETTTVSSFS--- 1853
T + +S+ P EG LT++P S V + S + +T+T ++ S
Sbjct: 1963 ASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEG 2022
Query: 1854 ---------LNVEYAIQAEKEVAGTLSPHVETTFSTEPTGLVLST--VMDRVVAENITQT 1902
+++ + +E+ P V TT G LST V + N T+
Sbjct: 2023 SSSPTTAGGTSIQTSTPSERTTPLAGMP-VSTTLVVSSEGNTLSTTPVDSKTQVTNSTEA 2081
Query: 1903 SREIVI---SERLGEPNYGAEIRGFSTGFPLEEDFSGDFREYSTVSHPIAKEETVMMEGS 1959
S S + P+ G+ + T PL + V+ P A + S
Sbjct: 2082 SSSATAEGSSMTISAPSEGSPL---LTSIPLST---------TPVASPEASTLSTTPVDS 2129
Query: 1960 GDAAFRDTQTSPSTVP---TSVHISHISDSEGP------SSTMVSTSAFPW--------- 2001
T+ S S +P TS+ S SD P S+T+V++SA
Sbjct: 2130 NSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTS 2189
Query: 2002 EEFTSSAEGSGEQLVTVSSSVVPVLPS-AVQKFSGTASSIIDEGLGEVGTVNEIDRRSTI 2060
T+S E + +S+ PS F+ S + E T++ ++
Sbjct: 2190 TPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTST 2249
Query: 2061 LPTAEVEGTKAPVEKEEVKV-SGTVST-NFPQTIEPAK--LWSRQEVNPVRQEIESETTS 2116
T E T +P E + + T+S P T P L + EV+ + S T
Sbjct: 2250 PVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTL-----STTPV 2304
Query: 2117 EEQIQEEKSFESPQNSPATEQTIFDSQTFTETELKTTDYSVLTTKKTYSDDKEMKEEDTS 2176
+ S E+ P E T + T +E T V TT + + T+
Sbjct: 2305 DSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTL---STT 2361
Query: 2177 LVNMSTP-DPDANGLESYTTLPEATEKSHFFLATALVTESIPAEHVVTDSPIKKEESTKH 2235
+ STP + S TT + + + + + S+P V+ P+ E++ H
Sbjct: 2362 PADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVP----VSTMPVVSSEASTH 2417
Query: 2236 FPKGM-RPTIQESDTELLFSGLGSGEEVLPTLPTESVNFTEVEQINNTLYPHTSQVESTS 2294
+ T + TE S + +PT P S T + + + P S T
Sbjct: 2418 STTPVDTSTPVTTSTEASSSPTTAEGTSIPTSP-PSEGTTPLASMPVSTTPVVSSEAGTL 2476
Query: 2295 SDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVTSTTLIEILSDTGAEGPT-VAPLPFS- 2352
S D + P+ + T E S S T+ I + T +EG T + +P S
Sbjct: 2477 STTPVDTST---------PMTTST---EASSSPTTAEDIVVPISTASEGSTLLTSIPVST 2524
Query: 2353 TDIGHPQNQTVRWAEEIQTSRPQTITEQDSNKNSSTAEINETTTSSTDFLARAYGFEMAK 2412
T + P+ T+ S T TE S+ S+ T+T S +
Sbjct: 2525 TPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEG------STPLRS 2578
Query: 2413 EFVTSAPKPSDLYYEPSGEGSGEVDIVDSFHTSATTQATRQESSTTFVSDGSLEKHPEVP 2472
V++ P S E S + VD + T +T SS T D S+ P
Sbjct: 2579 MPVSTKPLASS---EASTLSTTPVDT-----SIPVTTSTETSSSPTTAKDTSM---PIST 2627
Query: 2473 SAKAVTADGFPTVSVMLPLHSEQNKSSPDPTSTLSNTVSYERSTDGSFQDRFREFEDSTL 2532
++ T+ VS M SE + S P T V+ T S ++
Sbjct: 2628 PSEVSTSLTSILVSTMPVASSEASTLSTTPVDT-RTLVTTSTGTSSSPTTAEGSSMPTST 2686
Query: 2533 KPNRKKPTENIIIDLDKEDKDLILTITESTILEILPELTSDKNTIIDIDHTKPVYEDILG 2592
R P NI++ +L +E++ L P TS T + P +
Sbjct: 2687 PGERSTPLTNILV------STTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTS 2740
Query: 2593 MQTDIDTE---------VPSEPHDSNDESNDDSTQVQEIYEAAVNLSLTEETFEGSADVL 2643
M+ ++ V + P S++ S +T V ++ +T T S+
Sbjct: 2741 MRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVD------TSIPVTTSTEASSSPTT 2794
Query: 2644 ASYTQATHDESMTYEDRSQLDHMGFHFTTGIPAPSTETELDVLLPTATSLPI--PRKSAT 2701
A T + S E + L M + T P S+E P TS P+ K+++
Sbjct: 2795 AEVT--SMPTSTPSETSTPLTSMPVNHT---PVASSEAGTLSTTPVDTSTPVTTSTKASS 2849
Query: 2702 VIPEIEGIKAEAKALDDMFESSTLSDGQAIADQSEI--IPTLGQFERTQEEYEDKKHAGP 2759
EGI + ST S+G + + P T
Sbjct: 2850 SPTTAEGI---------VVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPV 2900
Query: 2760 SFQPEFSSGAEEALVDHTPYL--SIATTHLMDQSVTEVPDVMEGSNPPYYTDTTLAVSTF 2817
+ E SS A P S +T L V+ VP + GS + T + T
Sbjct: 2901 TTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVP--VAGSEASTLSTTPVDTRTP 2958
Query: 2818 AKLSSQTPSSPLTIYSGS---EASGHTEIP----QPSALPGIDVGSSVMS--PQDSFKEI 2868
S++ SSP T S G P S +P +S +S P D+ +
Sbjct: 2959 VTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPV 3018
Query: 2869 HVNIEATFKPSSEEYLHITEPPSLSPDTKLEPSEDDGKPELLEEMEASPTELI-----AV 2923
+ EA+ P++ E I T L P + E T + V
Sbjct: 3019 TTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVV 3078
Query: 2924 EGTEILQDFQNKTDGQVSGEAIKMFPTIKTPEAGTVITT--ADEIELEGATQWPHSTSAS 2981
TE+ + T + + I + TP G ++T + + P TS
Sbjct: 3079 TSTEV---SSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTP 3135
Query: 2982 ATYGVEAGVVPWLSPQTS---ERPTLSSSP-EINPETQAALIRGQDSTIAASEQQVAARI 3037
T EA P S TS P+ S+P P + ++ +DST++A+ + +
Sbjct: 3136 VTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPV 3195
Query: 3038 LDSNDQATVNPVEFNTEVAT 3057
S +AT + T + T
Sbjct: 3196 TTST-EATSSTTAEGTSIPT 3214
Score = 129 bits (324), Expect = 5e-29
Identities = 495/2341 (21%), Positives = 778/2341 (33%), Gaps = 320/2341 (13%)
Query: 929 EDVDLSKPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVP 988
+ V +T T+ VE ++S S+ E T+ ++SS T + T
Sbjct: 57 QHVRTGSAANTATGTTSTNVVEPRMYLSCSTNPEMTS-IESSVTSDTPGVSSTRM----- 110
Query: 989 SVPSEDEVLGEPSQDILVIDQTRLEATISPETMRTTKITEGTTQEEFPWKEQTAEKPVPA 1048
P+E E + D + + E T SP T T + T EE P
Sbjct: 111 -TPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPL 169
Query: 1049 LSSTAWT----PKEAVTPLDEQEGDGSAYTVSEDELL---TGSERVPVLETTPVGKIDHS 1101
S A+T + TPL S+ T E + T SE L + P + +
Sbjct: 170 PSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVA 229
Query: 1102 VSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTS--------- 1152
S +T V+ VT++ + + + GP +T T
Sbjct: 230 SSEAITLLTT-PVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVV 288
Query: 1153 -------SLSPFSTHITQL------MEETTTEKTSLEDIDLGSG---LFEKPKATELI-- 1194
S +P +T+I + TT E TS+ G L P +T +
Sbjct: 289 SSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVAT 348
Query: 1195 -EFSTIKV------------TVPSDITTAFSSVDRLHTTSAFKPSSAITKKPPLIDREPG 1241
E ST+ + T PS + T + L T++ + S+ +T P
Sbjct: 349 SEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSML-TSTLSEGSTPLTNMPVSTILVAS 407
Query: 1242 EETTSDMVIIGESTSHV--------PPTTLEDIVAKETETDIDREYFTTSSPPATQPTRP 1293
E ++ I +S + V PTT ED + T T + TS P +T P
Sbjct: 408 SEASTTSTIPVDSKTFVTTASEASSSPTTAED-TSIATSTPSEGSTPLTSMPVSTTP--- 463
Query: 1294 PTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESKE 1353
V EA LST + T+ + + V P + S+
Sbjct: 464 --VASSEA---SNLSTTPVDSKTQ---------VTTSTEASSSPPTAEVNSMPTSTPSEG 509
Query: 1354 DEP---CSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQY 1410
P S T PV A L P +D E + + T+ P+
Sbjct: 510 STPLTSMSVSTMPVASSEASTLSTTP----VDTSTPVTTSSEASSSSTTPEGTSIPTSTP 565
Query: 1411 INGKHLVTTVPKDPEAAEARRGQFESVAPSQN---FSDSSESDTHPFVIAKTELSTAVQP 1467
G +T +P + S P+ + + SSE+ + T + T+
Sbjct: 566 SEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYS 625
Query: 1468 NESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDT 1527
T T S+ V+ E S + P E S T +G T T
Sbjct: 626 ERGT-TITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYT 684
Query: 1528 EVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIV 1587
E + P++ P ++ + E+ ++ T V V ST + +PT
Sbjct: 685 -------EGSTPLTSMPVNTT--LVASSEASTLS---TTPVDTSTPVTTSTEASSSPTTA 732
Query: 1588 PSSASAYVSEEEAVT-LIGNPWPDDLLSTKE-SWVEATPRQ-----VVELSGSSSIPITE 1640
++ + E T L P LL++ E S + TP S S TE
Sbjct: 733 DGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTE 792
Query: 1641 GSG---EAEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIYPVSEQPS 1697
G+ + + T + T+ TL T+ + + S P TT VS P+
Sbjct: 793 GTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNS----PVTTSTEVSSSPT 848
Query: 1698 ---AKVVPTKFVSE--TDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLIL 1752
+PT SE T + STT+ TT ++ V +ST+
Sbjct: 849 PAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTT 908
Query: 1753 PFELESPNVATSSDSGTRKSFMSLTTP-TQSEREMTDSTPVFTE----TNTLENLGAQTT 1807
P S S TTP SE +TPV T T+T T
Sbjct: 909 SEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTA 968
Query: 1808 EHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEVA 1867
E +SI EG T L +P S + A+ E +T+S+ ++ + E A
Sbjct: 969 EGTSIPTSTPSEGTTPLTSTPVSHTL-------VANSEASTLSTTPVDSNTPLTTSTE-A 1020
Query: 1868 GTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFSTG 1927
+ P E T T ST + R+ S E ST
Sbjct: 1021 SSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSET------------------STL 1062
Query: 1928 FPLEEDFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVPTSVHISHISDSE 1987
D S YS S + M S + + T ++VP S + S++
Sbjct: 1063 STTPADTSTPVTTYSQASSSSTTADGTSMPTS---TYSEGSTPLTSVPVSTRLVVSSEAS 1119
Query: 1988 GPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPS---------------AVQK 2032
S+T V TS T+S E S +S+ PS V
Sbjct: 1120 TLSTTPVDTSI----PVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSS 1175
Query: 2033 FSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEG--TKAPVEKEEVKVSGTVSTNFPQ 2090
+ T S+ + +V T E S+ PTAEV T P E+ S V
Sbjct: 1176 EANTLSTTPVDSKTQVATSTE---ASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVA 1232
Query: 2091 TIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTETEL 2150
+ E + L + +ET+S E S P ++ + T+ S + T +
Sbjct: 1233 SSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSL--PTSTTSEGSTLLTSIPVSTTLV 1290
Query: 2151 KTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDP-DANGLESYTTLPEATEKSHFFLAT 2209
+ + S L T + + + S S+P P + + + T T + + T
Sbjct: 1291 TSPEASTLLTTPVDTKGPVVTSNEVS----SSPTPAEGTSMPTSTYSEGRTPLTSIPVNT 1346
Query: 2210 ALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLP-- 2267
LV S A +++ +P+ + T + S G L ++P
Sbjct: 1347 TLVASS--AISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVS 1404
Query: 2268 TESVNFTEVEQIN----NTLYPHTSQVESTSSDKIEDFNRMENVAKEVG--PL----VSQ 2317
T V +E ++ +T P T+ E+TSS + + G PL VS
Sbjct: 1405 TTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSN 1464
Query: 2318 TDIFEGSGSVTSTTLIE-----------ILSDTGAEGPTVA---PLPFSTDI-GHPQNQT 2362
T + S STT ++ S T AEG ++A P ST + P + T
Sbjct: 1465 TPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTT 1524
Query: 2363 VRWAEEIQTSRPQTITEQDSNKNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPS 2422
+ EI + S A + TT T Y +TS P +
Sbjct: 1525 TVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTY--SEGSTPLTSLPVST 1582
Query: 2423 DLYYEPSGEGSGEVDIVDSFHTSATTQA----TRQESSTTF--VSDGS--LEKHP----E 2470
L I +A+T+A T + SS T S+GS L P
Sbjct: 1583 MLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTP 1642
Query: 2471 VPSAKAVTADGFPTVSVMLPLHSEQNKSSPDP---TSTLSNTVSYERSTDGSFQDRFREF 2527
V S +A T P S + S + SSP P TS ++T + R+ S R
Sbjct: 1643 VASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPV 1702
Query: 2528 EDSTLKPNRKKPTENII-IDLDKEDKDLILTITESTILEILPELTSDKNTIIDIDHTKPV 2586
S + P +N + E + T +++ P + T I + T +
Sbjct: 1703 ASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVL 1762
Query: 2587 YEDILGMQ-TDIDTEVP----SEPHDSNDESNDDSTQVQEIYEAAVNLSLTEETFEGSAD 2641
+ + T IDT P +E S + S + E L+ T + A+
Sbjct: 1763 SSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVAN 1822
Query: 2642 VLASYTQATHDES------MTYEDRSQLDHMGFHFTTGIPAPSTETELDVLLPTATSLPI 2695
AS T +S T S G T P+ + + + T T
Sbjct: 1823 SEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASS 1882
Query: 2696 PRKSATVIPEIEGIKAEAKALDDMFESSTLSDGQAIADQSEIIPTLGQFERTQEEYEDKK 2755
+ + P + A + S T +DG ++ + P G+ T
Sbjct: 1883 ETNTLSTTPAVTSTPVTTYA--QVSSSPTTADGSSMPTST---PREGRPPLTSIPVSTTT 1937
Query: 2756 HAGPSFQPEFSSGAEEALVDHTPYLSIATTHLMDQSVTEVPDVMEGSNP--PYYTDTTLA 2813
A ++ A+ T + ++ D + P EGS P TTL
Sbjct: 1938 VASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLV 1997
Query: 2814 VSTFAKLSSQTP-------------SSPLTIYSGSEASGHTEIPQPSALPGIDVGSSVM- 2859
VS+ A S TP SS T G+ T + + L G+ V ++++
Sbjct: 1998 VSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVV 2057
Query: 2860 ---------SPQDSFKEIHVNIEATFK------------PSSEEYLHITEPPSLSPDTKL 2898
+P DS ++ + EA+ PS L + P S +P
Sbjct: 2058 SSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASP 2117
Query: 2899 EPSE------DDGKPELLE-EMEASPTELIAVEGTEILQDFQNKTDGQVSGEAIKMFPTI 2951
E S D P + E+ +SP I EGT + Q S + + P
Sbjct: 2118 EASTLSTTPVDSNSPVITSTEVSSSP---IPTEGTSM----------QTSTYSDRRTPLT 2164
Query: 2952 KTPEAGTVITTADEIELEGATQWPHSTSASATYGVEAGVVPWLSPQTSERPTLSSSPEIN 3011
P + TV+ ++ + + P TS T EA SP TSE ++ +S
Sbjct: 2165 SMPVSTTVVASS---AISTLSTTPVDTSTPVTNSTEAR----SSPTTSEGTSMPTSTPSE 2217
Query: 3012 PETQAALIRGQDSTIAASEQQVAARILDSNDQATVNPVEFNTEVATPPFSLLETSNETDF 3071
T + + SE A L + T PV +TE + P + TS T
Sbjct: 2218 GSTPFTSMPVSTMPVVTSE----ASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTST 2273
Query: 3072 L 3072
L
Sbjct: 2274 L 2274
Score = 102 bits (253), Expect = 8e-21
Identities = 352/1662 (21%), Positives = 569/1662 (34%), Gaps = 270/1662 (16%)
Query: 348 PKEATTIDLSILAETASPSLSKEPQMVSDRTTPI--------------IPLVDELPVIPT 393
P E +T SIL T P S E +S TTP+ P E +PT
Sbjct: 2628 PSEVSTSLTSILVSTM-PVASSEASTLS--TTPVDTRTLVTTSTGTSSSPTTAEGSSMPT 2684
Query: 394 EFP-----PVGNI-VSFEQKATVQPQAI-TDSLATKLPTPTGS-------TKKPWDMDDY 439
P P+ NI VS A + + T + T P T + T + M
Sbjct: 2685 STPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRIS 2744
Query: 440 SPS-ASGPLGKLDISEIKEEVLQSTTGVSHYATDSWDGVVEDKQTQESVTQIEQIEVGPL 498
+PS S PL + +S + +++T VS A D+ V + S T E V +
Sbjct: 2745 TPSDGSTPLTSILVSTLPVASSEAST-VSTTAVDTSIPVTTSTEASSSPTTAE---VTSM 2800
Query: 499 VTSMEILKHIPSKEFPVTETPLVTARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDE 558
TS P PV TP+ ++ S T V T + + T+ + +
Sbjct: 2801 PTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTP---VDTSTPVTTSTKASSSPTTAEGI 2857
Query: 559 DRTLTVGSDESTLIFDQIP---------EVITVSKTSEDTIHTHLEDLESVSASTTVSPL 609
++ S+ STL+ IP E T+S T DT E S+ TT
Sbjct: 2858 VVPISTASEGSTLL-TSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGT 2916
Query: 610 IMPDNNGSSMDDWEERQTSGRITEEFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEGIS 669
MP + T ++ +ST P + + P +
Sbjct: 2917 SMPIS------------TPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAE 2964
Query: 670 TVIYPSLQ--TEM---THRRERTETLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGM 724
P+ T M T RT + M T E T S T V +
Sbjct: 2965 ASSSPTTAEGTSMPISTPGERRTP--LTSMSVSTMPVASSEASTLSRTPADTSTPVTTST 3022
Query: 725 KLSTSLSEPIHVTESSVEMTKSFDFPTLITKLSAEPTEVRDMEEDFTATPGTTKYDEN-- 782
+ S+S P + + ++ + T +T + T V E +T TT D N
Sbjct: 3023 EASSS---PTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPE---ASTLSTTPVDSNSP 3076
Query: 783 -ITTVLLAHGTLSVEAATVSKWSWDEDNT--TSKPLESTEPSASSKLPPALLTTVGMNGK 839
+T+ ++ E ++ ++ E +T T P+ +T ++S+ ++T+
Sbjct: 3077 VVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSA------ISTLSTTPV 3130
Query: 840 DKDIPSFTEDGA------DEFTLIPDSTQKQLEEVTDEDIAAHGKFTIRFQPTTSTGI-- 891
D P T A E T +P ST + G + + P ++ +
Sbjct: 3131 DTSTPVTTSTEAHSSPTTSEGTSMPTSTPSE------------GSTPLTYMPVSTMLVVS 3178
Query: 892 AEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEG 951
+E STL + + P TSTE T EG+++ + P+++VP V
Sbjct: 3179 SEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVP-------VSN 3231
Query: 952 LAFVSYSSTQEPTTYVDSSHTIPLSV----IPKTDWGVLVP-SVPSEDEVLGEPSQDILV 1006
S ++ TT VDS+ + S P T G +P S PSE G +
Sbjct: 3232 TPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSE----GSTPLTSMP 3287
Query: 1007 IDQTRLEATISPETMRTTKITEGTTQEEFPWKEQTAEKP--VPALSSTAWTPKEAVTPLD 1064
+ T T++ T T T Q + P S T E TPL
Sbjct: 3288 VSTT----TVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLT 3343
Query: 1065 EQEGDGSAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTP 1124
+ SE L+ PV +TPV + P A + TP
Sbjct: 3344 NMSFSTTPVVSSEASTLS---TTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTP 3400
Query: 1125 RIGPKVSLSPGPEQKYETEGSS--------TTGFTSSLSPFSTHITQLMEETTTE-KTSL 1175
VS +P + T ++ TT +S SP T L TT+E T L
Sbjct: 3401 LASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPL 3460
Query: 1176 EDIDLGSGLFEKPKATEL----IEFST-IKVTVPSDITTAFSSVDRLHTTSAFKPSSAIT 1230
+ L + +A+ L ++ ST + + P++ + + V + T++A + S+ +T
Sbjct: 3461 SIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLT 3520
Query: 1231 KKP----PLIDREPGEETT----SDMVIIGESTSHVPPTTLEDIVAKETETDIDREYFTT 1282
P P+ E +T S+ + S + P TL+ + + TT
Sbjct: 3521 NMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTT 3580
Query: 1283 SSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRENKTGRMSDLSV 1342
+T V EA STP P+ + P + + V
Sbjct: 3581 MLLSSTY------VTSSEA------STPSTPSVDRSTP------VTTSTQSNSTPTPPEV 3622
Query: 1343 IGHPIDSESKEDEPCSEETDPVHDLMAEILPE-FPDIIEIDLYHSEENEEEEEECANATD 1401
I P+ + S+ P + PV I + +D + +
Sbjct: 3623 ITLPMSTPSEVSTPLT--IMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPE 3680
Query: 1402 VTTTPSVQYINGKHLVTTVPKDPEAAEARRG---QFESVAPSQNFSDSSESDTHPFVIAK 1458
TT P G +TT+P + G SV S + S+E+ + +
Sbjct: 3681 GTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDS 3740
Query: 1459 TELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVP-FHEEFESGTAKK 1517
T +S ++ ST T L T +PE+S P++P + TA +
Sbjct: 3741 TTMSVSMPMEISTLGTTILVSTTPVTRFPESST----------PSIPSVYTSMSMTTASE 3790
Query: 1518 GAESVTERDTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKS 1577
G+ S T E + P ++ E + + I+ + +
Sbjct: 3791 GSSSPTT------------LEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTP 3838
Query: 1578 TSVTYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGS--SS 1635
T TP + + A ++ E T+ + T E +TP + +S + +S
Sbjct: 3839 PGDTSTPLLTSTKAGSFSIPAEVTTI-------RISITSE---RSTPLTTLLVSTTLPTS 3888
Query: 1636 IPITEGSGEAEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIYPVSEQ 1695
P + D T FT TD + T T+ S +ITE P TTI+
Sbjct: 3889 FPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVS-VITEG--STPGTTIF----- 3940
Query: 1696 PSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFE 1755
I ST V TTG ST V +ST E
Sbjct: 3941 -------------------IPSTPVTSSTADVFPATTGAVST-PVITST----------E 3970
Query: 1756 LESPNVATSSDSGTRKSFMSLTTPTQSERE----MTDSTPVFTETNTLENLGAQTTEHSS 1811
L +P+ ++SS + + + TTP + +T ST T T + S+
Sbjct: 3971 LNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSA 4030
Query: 1812 IHQPGVQEGLTTLPRSPASVFMEQGSGEA-----------AADPETTTVSSFSLNVEYAI 1860
P +TT P +P+S + + ++ P TT+ SS ++N E
Sbjct: 4031 TSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPE--- 4087
Query: 1861 QAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQT 1902
A + P TT + PT + + + N T T
Sbjct: 4088 -AVTTMTTRTKPSTRTT--SFPTVTTTAVPTNTTIKSNPTST 4126
Score = 42.7 bits (99), Expect = 0.006
Identities = 124/597 (20%), Positives = 199/597 (33%), Gaps = 113/597 (18%)
Query: 348 PKEATTIDLSILAETASPSLSKEPQMVSDRTTPIIPLVDELPVIPTEFPPVGNIVSFEQK 407
P E T+ +S +E ++P L+ P + T LPV
Sbjct: 3619 PPEVITLPMSTPSEVSTP-LTIMPVSTTSVTISEAGTASTLPV----------------- 3660
Query: 408 ATVQPQAITDSLATKLPTPTGSTKKPWDMDDYS-PSASGPLGKLDISEIKEEVLQSTTGV 466
T P + +++ TP G+T W + S P + P+ ++ + L + + V
Sbjct: 3661 DTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVV 3720
Query: 467 SHYATDSWDGVVEDKQTQESVTQIEQI--EVGPLVTSMEILKHIPSKEFPVTETPLVTA- 523
+ + + T +S T + E+ L T++ ++ P FP + TP + +
Sbjct: 3721 TSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTI-LVSTTPVTRFPESSTPSIPSV 3779
Query: 524 --RMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVIT 581
M + + +E T E TT ++ S+ STL+ + I+
Sbjct: 3780 YTSMSMTTASEGSSSPTTLEGTTT--------------MPMSTTSERSTLLTTVLISPIS 3825
Query: 582 VSKTSE-DTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEF---LG 637
V SE T+ T D T +PL+ GS E IT E L
Sbjct: 3826 VMSPSEASTLSTPPGD--------TSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLT 3877
Query: 638 KYLSTTPFPSQHRTEIELFPYSGDKILVE---GISTVIYPSLQTEMTHRRERTETLIPEM 694
L +T P+ + G I ST PS T T T+ +
Sbjct: 3878 TLLVSTTLPTS---------FPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSV 3928
Query: 695 RTDTYTDEIQEEITKSPFMGKTEE-------EVFSGMKLSTSLSEPI---HVTESSVEMT 744
T+ T I +P T + V + + ST L+ P T +S T
Sbjct: 3929 ITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTT 3988
Query: 745 KSFDFPTLITK-------LSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEA 797
K F P + T +S P+ R T + G T ++ H + SV
Sbjct: 3989 KEFTTPAMTTAAPLTYVTMSTAPSTPR------TTSRGCTTSASTLSATSTPHTSTSVTT 4042
Query: 798 --ATVSKWSWDEDNTTSKPLESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFT 855
T S S TS + T P A S PP S T + T
Sbjct: 4043 RPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSA------------SSTTVNPEAVT 4090
Query: 856 LIPDSTQKQLEEVTDEDIAAHGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITST 912
+ T+ T F T+T + +T++ + T P T+T
Sbjct: 4091 TMTTRTKPSTR-------------TTSFPTVTTTAVPTNTTIKSNPTSTPTVPRTTT 4134
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 160 bits (404), Expect = 3e-38
Identities = 585/2748 (21%), Positives = 929/2748 (33%), Gaps = 436/2748 (15%)
Query: 576 IPEVITVSKTSEDTIHTHLEDLESVSASTTVSPLI--MPDNNGSSMDDWEERQTSGRITE 633
+ E T ++ T TH + S + S + PD +G++ TSGR
Sbjct: 1158 VEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSS-AHSTTSGR--- 1213
Query: 634 EFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQT--------EMTHRRE 685
G+ STT S TEI P S + ST Y S ++ MT
Sbjct: 1214 ---GE--STTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGV 1268
Query: 686 RTETLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMTK 745
E+ + + + T +P + + V+S + ST + H T +SV +
Sbjct: 1269 GEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEE 1328
Query: 746 SFDF----PTLITKLSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEAATVS 801
F + T L E + + E+ TA PG+ T + AT++
Sbjct: 1329 PTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA------------STQTGLPATLT 1376
Query: 802 KWSWDEDNTTSKPLESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDS- 860
E++TT S+ S +KL PA TT G+ G+ PS + E T +P S
Sbjct: 1377 TADLGEESTT---FPSSSGSTGTKLSPARSTTSGLVGEST--PSRLSPSSTETTTLPGSP 1431
Query: 861 TQKQLEEVTDEDIAAHGKFTIRFQP--TTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYA 918
T L E + + P TTS+G++E +S+T P T T
Sbjct: 1432 TTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSE-----ESSTSHSQPGSTHTTA---- 1482
Query: 919 TMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSST------QEPTTYVDSSHT 972
D + +S P +H+S+ A +S ST Q+ TT+ S
Sbjct: 1483 ---------FPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGD 1533
Query: 973 IPLSVIPKTDW--GVLVPSVPSEDEVLGEPSQDILVIDQTRLEATISPETMRTTKITE-G 1029
+++P G++ S P+ L T++P + + + E
Sbjct: 1534 TETTLLPDDTITSGLVEASTPTHSST-------------GSLHTTLTPASSTSAGLQEES 1580
Query: 1030 TTQEEFPWKEQTAEKP-----VPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELL--- 1081
TT + +P T P P ST + + + TP + SE+
Sbjct: 1581 TTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHS 1640
Query: 1082 ----TGSERVPVLE----------TTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIG 1127
TG+ P T+P+ + PG+ T + +
Sbjct: 1641 SPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRS 1700
Query: 1128 PKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKTSLE----------- 1176
P +LSP + G S TS P STH T TT S E
Sbjct: 1701 PDTTLSPASTT---SSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGST 1757
Query: 1177 DIDLGSG-------------LFEKPKATE--LIEFSTIKVTVPSDITTAFSSVDRLHTTS 1221
D L G P +TE L+ +T + T SS HTT
Sbjct: 1758 DTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTT- 1816
Query: 1222 AFKPSSAITKK---------PPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKETE 1272
P+ + T++ P D P TT+ + +TSH P++ +
Sbjct: 1817 -LSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASS 1875
Query: 1273 TDIDREYFTT---SSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTK--FHPDINVYII 1327
T + R +T SSP AT T P ++ + P ST+ P+ +
Sbjct: 1876 TTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASG 1935
Query: 1328 EVRENKTGRMSDLSVIGHPIDSESK-EDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHS 1386
E++T S I P + S +EP S + P + FPD
Sbjct: 1936 RSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPG----STATTHFPDSSTTSGRSE 1991
Query: 1387 EENEEEEEECANATDVTTTPSV-QYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSD 1445
E + A T V S + G+ + + A G + S+ +
Sbjct: 1992 ESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTT 2051
Query: 1446 SSESDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPE-----------TSEHFS 1494
S P +T+ +E + T+ S + +P+ T+ H S
Sbjct: 2052 FHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS 2111
Query: 1495 GGEPDVF-------PTVPFHEEFESGTAKKGAESVTERDTEVGHQAHE-----HTEPVS- 1541
G D + P E S ++ ++ + + H+ P S
Sbjct: 2112 PGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGST 2171
Query: 1542 ---LFPE--------ESSGEIAIDQESQKIAFARATEVTFGEEVEKST-----SVTYTPT 1585
LFP+ E+S + S + + A+ + G + E + + T+T
Sbjct: 2172 HTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTP 2231
Query: 1586 IVPSSASAYVSEEEAVTLIGNP-------WPDDLLSTKESWVEATPRQVVELSG---SSS 1635
PS+A+A V EE+ T +P +P ++ S + SG SS+
Sbjct: 2232 SPPSTATAPV--EESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSA 2289
Query: 1636 IPITEGSGEAEEDEDTM-FTMVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIYPVS- 1693
T G GE+ + T +T L TT L T+ + P TT+ P S
Sbjct: 2290 HSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSP---RSPTTTLSPASM 2346
Query: 1694 -------------EQP-------SAKVVPTKFVSETDTSEWISS---------------- 1717
QP S T +SE T+ + SS
Sbjct: 2347 TSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTS 2406
Query: 1718 ------TTVEEKKRK-------EEEGTTGTASTFEVYSSTQRSDQLILPFELESPNV--- 1761
TT + E+ T+G + + S Q LP L + ++
Sbjct: 2407 VRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEE 2466
Query: 1762 -----ATSSDSGTRKS-FMSLTTPTQSEREMTDSTPVFTETNTLENLGAQTTEHSSIHQP 1815
++S +GT S S T+ E + +P TET TL G+ TT P
Sbjct: 2467 STTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLP--GSPTT-------P 2517
Query: 1816 GVQEGLTTL---PRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEVAGTLSP 1872
+ E TT PRSP + + + E++T S + + LS
Sbjct: 2518 SLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSR 2577
Query: 1873 HVETTFS----TEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPN-----YGAEIRG 1923
H T+ S T+ T L ST E+ T S L + +G E
Sbjct: 2578 HSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTT 2637
Query: 1924 F--------STGFPLEEDFSGDFREYSTVSHPIAKEETVMMEGSGDA-AFRDTQTSPSTV 1974
F +T FP SG + V T + S + + T+ T
Sbjct: 2638 FHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTH 2697
Query: 1975 PTSVHISHISDSEGPSSTMVSTS------AFPWEEFTSSAEGSGEQLVTVSSSVVPVLPS 2028
P S H + S + ST+ + P F +S+ SG + S++ P
Sbjct: 2698 PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGH---SEKSTIFHSSPD 2754
Query: 2029 AVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNF 2088
A +A S G GE T + I ST + T + G+ E + S
Sbjct: 2755 ASGTTPSSAHSTTS-GRGE-STTSRISPGSTEITT--LPGSTTTPGLSEASTTFYSSPRS 2810
Query: 2089 PQT-IEPAKLWS----------RQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQ 2137
P T + PA + S R + + +T+ + EE + + +TE
Sbjct: 2811 PTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTET 2870
Query: 2138 TIFDSQTFTET--ELKTTDYSVLTTKKT--YSDDKE---MKEEDTSLVNMSTPDPDANGL 2190
T+F T T E TT +S + T +++D + EE T+ +P GL
Sbjct: 2871 TVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPG--SPASTQTGL 2928
Query: 2191 ESYTTLPEATEKSHFFLATALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTE 2250
+ T + E+S F +++ T + + T S + E + P + P+ E+ T
Sbjct: 2929 PATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGEST----PSRLSPSSTETTTL 2984
Query: 2251 LLFSGLGSGEEVLPTLPTESVNF-TEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAK 2309
G P+L +S F T + TL P T+ TSS E E+
Sbjct: 2985 -------PGSPTTPSLSEKSTTFYTSPRSPDATLSPATT----TSSGVSE-----ESSTS 3028
Query: 2310 EVGPLVSQTDIFEGSGSVTSTTLIEILSDTGAEGPTVAPL-PFSTDIGHPQNQTVRWAE- 2367
P + T F S + TS E + ++G T A L P ST Q+ +
Sbjct: 3029 HSQPGSTHTTAFPDS-TTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSS 3087
Query: 2368 ----EIQTSRPQTIT----EQDSNKNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAP 2419
E TIT E + +SST ++ T T ++ A G + S P
Sbjct: 3088 PGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSA---GLQEESTTFQSWP 3144
Query: 2420 KPSDLYYEPSGEGSGEVDIVDSFHT--SATTQATRQESSTTFVSDGSLEKHPEVPSAKAV 2477
SD P G + V++ ++H+ S+T SSTT G E+ V S+
Sbjct: 3145 SSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTL---GRSEESTTVHSSPGA 3201
Query: 2478 TADG-FPTVSVMLPLHSEQNKSSPDPTSTLSNTVSYERSTDGSFQDRFREFEDSTLKPNR 2536
T FPT S L E +SP + + T +T ++ F S P+
Sbjct: 3202 TGTALFPTRSATSVLVGEPT-TSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDT 3260
Query: 2537 KKPTENIIIDLDKEDKDLILTITESTILEILPELT-----SDKNTIIDIDHTKPVYEDIL 2591
+ E+ + ST P T S ++T H+ P D
Sbjct: 3261 TLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQEST---ASHSSPGSTDTT 3317
Query: 2592 GMQTDIDTEVPSEPHDSNDESNDDSTQVQEIYEAAVNLSLTEETFEGSADVLASYTQATH 2651
+ T P + S ST+ + + L E + + + +T +
Sbjct: 3318 -LSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSP 3376
Query: 2652 DESMTYEDRSQLDHMGFHFTTGIPAPSTETELDVLLPT-----------------ATSLP 2694
S T + S + PAP T T V L T +T+L
Sbjct: 3377 AGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLG 3436
Query: 2695 IPRKSATV----IPEIEGIKAEAKALDDMFESSTLSDGQAIADQSEIIP----TLGQFER 2746
+S TV + + E ST + Q+ P T G+ E
Sbjct: 3437 RSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE 3496
Query: 2747 TQEEYEDKKHAGPSFQPEFSSGAEEALVDHTPYLSIATTHLMDQSVT----EVPDVMEGS 2802
+ + H S S+ EE H+ S ATTH D S T E S
Sbjct: 3497 STTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSS 3556
Query: 2803 NPPYYTDTTLAVSTFAKLSSQTPSSPLTIYSGSEASGHTEIPQPSALPGIDVGSSVM--S 2860
T A ST + L ++ +SP++ SGS + T +P + PG+ S+ S
Sbjct: 3557 QDATGTIVLPARSTTSVLLGESTTSPIS--SGSMET--TALPGSTTTPGLSEKSTTFHSS 3612
Query: 2861 PQDSFKEIHVNIEATFKPSSEEYLHITEPPSLS----PDTKLEPSEDDGKPELLEEMEAS 2916
P+ + + S E + P S PD+ P ++
Sbjct: 3613 PRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 3672
Query: 2917 PTELIAVEGTEILQDFQNKTDGQVSGEAIKMFPTIKTPEAGTVITTADEIEL-------E 2969
T L+ T ++ T SG T +P + T ++ E
Sbjct: 3673 DTTLLPASTTTSGSSQESTTSHSSSGST----DTALSPGSTTALSFGQESTTFHSSPGST 3728
Query: 2970 GATQWPHSTSASATYGVEAGVVPWL-SPQTSERPTLSSSPEINPETQA 3016
T +P ST++S V SP+T+ P S+SP + E+ A
Sbjct: 3729 HTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTA 3776
Score = 158 bits (400), Expect = 8e-38
Identities = 613/2849 (21%), Positives = 942/2849 (33%), Gaps = 435/2849 (15%)
Query: 368 SKEPQMVSDRTTPIIPLVDELPVIP------TEFPPVGNIVSFEQKATVQPQAITDSLAT 421
S E ++ D TT L +PV T P G+ + T +
Sbjct: 729 STETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRP 788
Query: 422 KLPTPTGSTKKPWDMDDYSPSA---------SGPLGKLDISEIKEEVLQSTTGVSHYATD 472
PT T + +P SPS+ S G ++ S ST + +D
Sbjct: 789 APPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESD 848
Query: 473 SWDGVVEDKQTQESVTQIEQIEVGPLVTSMEILK---------HIPSKEFPVTETPLVTA 523
+ G E+ T S T I P TS + + + FP + T +
Sbjct: 849 TTSGRGEESTTSHSSTT-HTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRS 907
Query: 524 RMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVITVS 583
S + + T+ L LGE ++ GS E+T + P T
Sbjct: 908 EESTASHSSQDATGTIV-LPARSTTSVLLGESTTSP--ISSGSMETTAL----PGSTTTP 960
Query: 584 KTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGKYLSTT 643
SE + H S +TT+SP + S + T F +TT
Sbjct: 961 GLSERSTTFHSSPR---SPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDS--TTT 1015
Query: 644 PFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRERTETLIPEMRTDTYTDEI 703
P S+H T P S D L+ +T PS ++ +H + + T
Sbjct: 1016 PGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFG 1075
Query: 704 QEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMTKSFDFP-TLITKLSAEPTE 762
QE T G T +F S+ + E+S + S P T ++ S+
Sbjct: 1076 QESTTFHSNPGSTHTTLFPDSTTSSG------IVEASTRVHSSTGSPRTTLSPASSTSPG 1129
Query: 763 VRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPLEST---- 818
++ F P +T + T + T VE +T S TT P ST
Sbjct: 1130 LQGESTAFQTHPAST----HTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGH 1185
Query: 819 ---------EPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQ-LEEV 868
P AS P + +T +G+ + S G+ E T +P ST L E
Sbjct: 1186 SEKSTIFHSSPDASGTTPSSAHSTT--SGRGESTTSRISPGSTEITTLPGSTTTPGLSEA 1243
Query: 869 TDEDIAAHGKFTIRFQPT--TSTGIAEKSTLRDS---TTEEKVPPITSTE---GQVYATM 920
+ ++ T P TS G+ E+ST S +T V P ++T + T+
Sbjct: 1244 STTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTV 1303
Query: 921 EGSALGEVEDVDLSKPVSTVPQFAHTSEVEG---LAFVSYSSTQEPTTYVDSSHTIPLSV 977
S+ G E +TV + T+ V G F S ++ T + + S T L
Sbjct: 1304 YSSSRGSTE--------TTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGL-- 1353
Query: 978 IPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEATISPETMRT--TKITEGTTQEEF 1035
T+ P P+ + G P+ L E+T P + + TK++ +
Sbjct: 1354 ---TEESTAFPGSPASTQT-GLPA--TLTTADLGEESTTFPSSSGSTGTKLSPARSTTSG 1407
Query: 1036 PWKEQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPV 1095
E T + P+ + T P TP E + YT S R P +P
Sbjct: 1408 LVGESTPSRLSPSSTETTTLPGSPTTP-SLSEKSTTFYT---------SPRSPDATLSPA 1457
Query: 1096 GKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLS 1155
VS + T H T P LS P + ++GS+ ++LS
Sbjct: 1458 TTTSSGVS--EESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGST----EATLS 1511
Query: 1156 PFSTHITQLMEETT--------TEKTSLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDI 1207
P ST + L +++T TE T L D + SGL E T S P+
Sbjct: 1512 PGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASS 1571
Query: 1208 TTAFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIV 1267
T+A + T ++ SS T PP P E +T T H P++
Sbjct: 1572 TSA-GLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVST---------TYHSRPSSTPTTH 1621
Query: 1268 AKETETDIDREYFTT---SSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHP-DIN 1323
+ T + R +T SSP AT PT + ++P ST+ +
Sbjct: 1622 FSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGS 1681
Query: 1324 VYIIEVRENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMAEI-LPEFPDIIEID 1382
+ E T S + S SEE+ H FP +
Sbjct: 1682 TTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMP 1741
Query: 1383 LYHSEENEEEEEECANATDVTTTP-SVQYINGKHLVTTVPKDPEAAE--------ARRGQ 1433
E +TD T +P S + TT P + E G
Sbjct: 1742 GVSQESTASHSS--PGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGL 1799
Query: 1434 FESVAPSQNFSDSSESDTHP--FVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSE 1491
E+ P + + S + P + E +T S +T + T T+
Sbjct: 1800 LEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTS 1859
Query: 1492 HFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQA--HEHTEPVSLFPEESSG 1549
H G P PT H S T + ES T + V S EES+
Sbjct: 1860 H---GSPSSTPTT--HFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTA 1914
Query: 1550 EIAIDQESQKIAFARATEVTFGEEVEKS--TSVTYTPTIVPSSASAYVSEEEAVTLIGNP 1607
+ +Q + F ++ + E ++ +S T+T + PS+ SA V E
Sbjct: 1915 YHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEE---------- 1964
Query: 1608 WPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTDT 1667
P S+ S SG S E S + +D T+V L R+TT
Sbjct: 1965 -PTSYHSSPGSTATTHFPDSSTTSGRS-----EESTASHSSQDATGTIV--LPARSTTSV 2016
Query: 1668 LITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKE 1727
L+ T+ I+ E TT P S T +SE STT R
Sbjct: 2017 LLGESTTSPISSGSME---TTALPGS-------TTTPGLSE-------KSTTFHSSPRSP 2059
Query: 1728 EEGTTGTASTFEVYSSTQRSDQLILPFELESPNVATSSDSGTRKSFMSLTTPTQSEREMT 1787
T AST S + + P S + DS T +T + S T
Sbjct: 2060 AT-TLSPASTTSSGVSEESTTSHSRP---GSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 2115
Query: 1788 DSTPVFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETT 1847
D+T + T T TT HSS GS + A P +T
Sbjct: 2116 DTTLLPASTTTSGPSQESTTSHSS-----------------------PGSTDTALSPGST 2152
Query: 1848 TVSSFSLNVEYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIV 1907
T SF TTF + P + D + I + S +
Sbjct: 2153 TALSFG-------------------QESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRV- 2192
Query: 1908 ISERLGEPNYGAEIRGFSTGFPLEEDFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDT 1967
+ G+ S G+ + T HP + T + A ++
Sbjct: 2193 ------HSSTGSPRTTLSPASSTSPGLQGESTAFQT--HPASTHTTPSPPSTATAPVEES 2244
Query: 1968 QT---SPSTVPTS-----------------VHISHISDSEGPSSTMVSTSAFPWEEFTSS 2007
T SP + PT+ H S + PSS +TS +
Sbjct: 2245 TTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRI 2304
Query: 2008 AEGSGEQLVTVSSSVVPVLPSAVQKFSG---------TASSIIDEGLGEVGTVNEIDRRS 2058
+ GS E S+ P L A F + +S+ G+GE T + S
Sbjct: 2305 SPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGS 2364
Query: 2059 TILPTAEVEGTKAPVEKEEVKV-----SGTVSTNFPQT-------IEPAKLWSRQEVNPV 2106
T + T + +E V T +T FP+T EP SR
Sbjct: 2365 THSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHT 2424
Query: 2107 RQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTETELKTTDYSVLTTKKTYSD 2166
E TTS +E +F SPA+ QT + T T +L + ++ +
Sbjct: 2425 TLFTEDSTTS-GLTEESTAF---PGSPASTQTGLPA-TLTTADLGEESTTFPSSSGSTGT 2479
Query: 2167 DKEMKEEDTS-LVNMSTP------DPDANGLESYTTLPEATEKSHFFLATALVTESIPAE 2219
TS LV STP + L T P +EKS F + ++ +
Sbjct: 2480 TLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSP 2539
Query: 2220 HVVTDSPIKKEESTKHFPKGMRPTIQESDTELL----------FSGLGSGEEVLPTLPTE 2269
T S + +E ST H G T D+ S GS + L T
Sbjct: 2540 ATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTT 2599
Query: 2270 SVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVTS 2329
+ ++ +++ T S S F + E+ P + T +F S TS
Sbjct: 2600 TSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQ-ESTTFHSSPGSTHTTLF--PDSTTS 2656
Query: 2330 TTLIE----ILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSNKN 2385
+ ++E + S TG+ T++P ST G T QT P + S +
Sbjct: 2657 SGIVEASTRVHSSTGSPRTTLSPAS-STSPGLQGESTT-----FQT-HPASTHTTPSPPS 2709
Query: 2386 SSTAEINETTTSSTDFLARAYGFEMAKEF----VTSAPKPSDLYYEPSGEGSGEVDIVDS 2441
++TA + E+TT R+ G F TS + S + SG
Sbjct: 2710 TATAPVEESTT-----YHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTP---- 2760
Query: 2442 FHTSATTQATRQESSTTFVSDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSEQNKSSPD 2501
++ +T + R ES+T+ +S GS E T G T + + S
Sbjct: 2761 -SSAHSTTSGRGESTTSRISPGSTE---------ITTLPGSTTTPGLSEASTTFYSSPRS 2810
Query: 2502 PTSTLSNTVSYERSTDGSFQDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDLILTITES 2561
PT+TLS S G R ST + P L +E + + S
Sbjct: 2811 PTTTLS-PASMTSLGVGEESTTSRSQPGST--HSTVSPASTTTPGLSEESTTVYSSSPGS 2867
Query: 2562 TILEILPELTSDKNTIIDIDHTKPVYEDILGMQTDIDTEVPSEPHDSNDESNDDSTQVQE 2621
T + P T+ T + E P+ H S ST
Sbjct: 2868 TETTVFPRSTT----------------------TSVRGEEPTTFH-----SRPASTHTTL 2900
Query: 2622 IYEAAVNLSLTEET--FEGSADVLASYTQAT------HDESMTYEDRSQLDHMGFHFTTG 2673
E + LTEE+ F GS + AT +ES T+ S G TT
Sbjct: 2901 FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS-----GSTGTTL 2955
Query: 2674 IPAPST----------------ETELDVLLPTATSLPIPRKSATVIPEIEG----IKAEA 2713
PA ST TE L + T+ + KS T +
Sbjct: 2956 SPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPAT 3015
Query: 2714 KALDDMFESSTLSDGQAIADQSEIIP----TLGQFERTQEEYEDKKHAGPSFQP---EFS 2766
+ E S+ S Q + + P T G + + + + P S
Sbjct: 3016 TTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTAS 3075
Query: 2767 SGAEEALVDHTPYLSIATTHLMDQSVTEVPDVMEGSNPPY------YTDTTLAVSTFAKL 2820
S +++ H+ TT L D ++T ++E S P + +T T A ST A L
Sbjct: 3076 SLGQQSTTFHSSPGDTETTLLPDDTITS--GLVEASTPTHSSTGSLHTTLTPASSTSAGL 3133
Query: 2821 SSQTPSSPLTIYSGSEASGHTEIPQPSALPGIDVGSSVMSPQDSFKEIHVNIEATFKPSS 2880
++ T S +S T P + ++V ++ S S H + +T S
Sbjct: 3134 QEES----TTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRS 3189
Query: 2881 EEYLHITEPPSLSPDTKLEPSEDDGKPELLEEMEASPTELIAVEGTEILQDFQNKTDGQV 2940
EE + P + T L P+ L+ E SP I+ TE + T +
Sbjct: 3190 EESTTVHSSPG-ATGTALFPTR-SATSVLVGEPTTSP---ISSGSTETTALPGSTTTAGL 3244
Query: 2941 SGEAIKMFPTIKTPEA--GTVITTADEIELEGATQWPHSTSASATYGVEAGVVPWLSPQT 2998
S ++ + + ++P+ TT+ + E T S T + +P +S ++
Sbjct: 3245 SEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQES 3304
Query: 2999 --SERPTLSSSPEINPETQAALIRGQDST 3025
S S+ ++P + A G +ST
Sbjct: 3305 TASHSSPGSTDTTLSPGSTTASSLGPEST 3333
Score = 138 bits (348), Expect = 8e-32
Identities = 557/2644 (21%), Positives = 897/2644 (33%), Gaps = 392/2644 (14%)
Query: 562 LTVGSDESTLIFDQIPEVITVSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDD 621
++ GS E+T + P T SE + H S +TT+SP + S
Sbjct: 2026 ISSGSMETTAL----PGSTTTPGLSEKSTTFHSSPR---SPATTLSPASTTSSGVSEEST 2078
Query: 622 WEERQTSGRITEEFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMT 681
+ T F +TTP S+H T P S D L+ +T PS ++ +
Sbjct: 2079 TSHSRPGSTHTTAFPDS--TTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTS 2136
Query: 682 HRRERTETLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSV 741
H + + T QE T G T +F S+ + E+S
Sbjct: 2137 HSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSG------IVEAST 2190
Query: 742 EMTKSFDFP-TLITKLSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEAATV 800
+ S P T ++ S+ ++ F P +T + T + T VE +T
Sbjct: 2191 RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST----HTTPSPPSTATAPVEESTT 2246
Query: 801 SKWSWDEDNTTSKPLEST-------------EPSASSKLPPALLTTVGMNGKDKDIPSFT 847
S TT P ST P AS P + +T +G+ + S
Sbjct: 2247 YHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTT--SGRGESTTSRI 2304
Query: 848 EDGADEFTLIPDSTQKQ-LEEVTDEDIAAHGKFTIRFQPT--TSTGIAEKSTLRDS---T 901
G+ E T +P ST L E + ++ T P TS G+ E+ST S +
Sbjct: 2305 SPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGS 2364
Query: 902 TEEKVPPITSTE---GQVYATMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEG---LAFV 955
T V P ++T + T+ S+ G E +TV T+ V G F
Sbjct: 2365 THSTVSPASTTTPGLSEESTTVYSSSPGSTE--------TTVFPRTPTTSVRGEEPTTFH 2416
Query: 956 SYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEAT 1015
S ++ T + + S T L T+ P P+ + G P+ L E+T
Sbjct: 2417 SRPASTHTTLFTEDSTTSGL-----TEESTAFPGSPASTQT-GLPAT--LTTADLGEEST 2468
Query: 1016 ISPETMRTTKITEGTTQEEFPWK--EQTAEKPVPALSSTAWTPKEAVTP-LDEQEGDGSA 1072
P + +T T + E T + P+ + T P TP L E+
Sbjct: 2469 TFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYT 2528
Query: 1073 YTVSEDELL----TGSERVPVLETTPVGK--IDHSVSYP-----PG----AVTEHKVKTD 1117
S D L T S V +T + H+ ++P PG + T H
Sbjct: 2529 SPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGS 2588
Query: 1118 EVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETT-------- 1169
TL P + + GP Q+ T SS ++LSP ST +E+T
Sbjct: 2589 TDTTLLPAS----TTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGS 2644
Query: 1170 TEKTSLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSA- 1228
T T D SG+ E +T + + T S ++ + TT P+S
Sbjct: 2645 THTTLFPDSTTSSGIVE--ASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTH 2702
Query: 1229 ITKKPPLIDREPGEETTSDMVIIGES-TSHVPPTTLEDIVAKET---ETDIDREYFTTSS 1284
T PP P EE+T+ G + T+H P ++ ++++ + D T SS
Sbjct: 2703 TTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSS 2762
Query: 1285 PPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRENKTGRMSDLSVIG 1344
+T R + + + G ++T +T + + + T +S S+
Sbjct: 2763 AHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTS 2822
Query: 1345 HPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTT 1404
+ ES + H ++ P + SEE+ +T+ T
Sbjct: 2823 LGVGEESTTSR---SQPGSTHSTVSPASTTTPGL-------SEESTTVYSSSPGSTETTV 2872
Query: 1405 TPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTA 1464
P TT + E F S S + + +E T TE STA
Sbjct: 2873 FP--------RSTTTSVRGEEPT-----TFHSRPASTHTTLFTEDST---TSGLTEESTA 2916
Query: 1465 VQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESG-----TAKKGA 1519
P T L T E S F T+ SG T + +
Sbjct: 2917 F-PGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLS 2975
Query: 1520 ESVTERDTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTS 1579
S TE T G P + E S S + AT + G E STS
Sbjct: 2976 PSSTETTTLPG-------SPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTS 3028
Query: 1580 -----VTYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGS- 1633
T+T S+ ++ +S+E + + LS + + +Q S
Sbjct: 3029 HSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSP 3088
Query: 1634 -----SSIP-------ITEGSGEAEEDEDTMFTMVTDLSQRNT--TDTLITLDTSRIITE 1679
+ +P + E S ++ T +T S + + T + ++
Sbjct: 3089 GDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSD 3148
Query: 1680 SFFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTV-----EEKKRKEEEGTTGT 1734
+ P TT PV + P S T T+ + +S+T E G TGT
Sbjct: 3149 TTPSPPGTTAAPVEVSTTYHSRP----SSTPTTHFSASSTTLGRSEESTTVHSSPGATGT 3204
Query: 1735 ASTFEVYSSTQRSDQLILPFELESPNVATSSDSGTRKSFM--SLTTPTQSEREMT-DSTP 1791
A F S+T +L E P + S T + + S TT SE+ T S+P
Sbjct: 3205 A-LFPTRSATS-----VLVGE---PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSP 3255
Query: 1792 VFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEA---AADPETTT 1848
+T T +S GV E TT P S G E+T
Sbjct: 3256 RSPDT---------TLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTA 3306
Query: 1849 VSSFSLNVEYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVI 1908
S + + + A +L P TTF + P + + D A + + S +
Sbjct: 3307 SHSSPGSTDTTLSPGSTTASSLGPE-STTFHSGPGSTETTLLPDNTTASGLLEASTPVHS 3365
Query: 1909 SERLGEPNYGAEIRGFSTGFPLEEDFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQ 1968
S G P+ G +T + S F+ + ++T + +AF +
Sbjct: 3366 S--TGSPHTTLSPAGSTT----RQGESTTFQSWPN------SKDTTPAPPTTTSAFVELS 3413
Query: 1969 TSPSTVPTSVHISHISDSEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVV--PVL 2026
T+ P+S +H S S S+ G E+ TV SS V
Sbjct: 3414 TTSHGSPSSTPTTHFSAS-------------------STTLGRSEESTTVHSSPVATATT 3454
Query: 2027 PSAVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVST 2086
PS + T S +++E T + + + E + T E+ S T
Sbjct: 3455 PSPAR---STTSGLVEEST----TYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTT-- 3505
Query: 2087 NFPQTIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFT 2146
TI A +T+ ++E S+ S S AT S T
Sbjct: 3506 ---HTISSA-----------------PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSG 3545
Query: 2147 ETELKTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANG------LESYTTLPEAT 2200
+E T +S + T + + + L+ ST P ++G L TT P +
Sbjct: 3546 RSEESTASHS--SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLS 3603
Query: 2201 EKSHFFLATALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELL-------- 2252
EKS F ++ + + T S + +E +T H G T D+
Sbjct: 3604 EKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHST 3663
Query: 2253 --FSGLGSGEEVLPTLPTESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKE 2310
S GS + L T + ++ +++ T S S F + E+
Sbjct: 3664 TSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQ-ESTTFH 3722
Query: 2311 VGPLVSQTDIFEGSGSVTSTTLIE----ILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWA 2366
P + T +F S TS+ ++E + S TG+ T++P ST G T
Sbjct: 3723 SSPGSTHTTLF--PDSTTSSGIVEASTRVHSSTGSPRTTLSPAS-STSPGLQGESTA--- 3776
Query: 2367 EEIQTSRPQTITEQDSNKNSSTAEINETTTSSTDFLARAYGFEMAKEF----VTSAPKPS 2422
QT P + S +++TA + E+TT R+ G F TS
Sbjct: 3777 --FQT-HPASTHTTPSPPSTATAPVEESTT-----YHRSPGSTPTTHFPASSTTSGHSEK 3828
Query: 2423 DLYYEPSGEGSGEVDIVDSFHTSATTQATRQESSTTFVSDGSLEKHPEVPSAKAVTADGF 2482
+ S + SG ++ +T + R ES+T+ +S GS E T G
Sbjct: 3829 STIFHSSPDASGTTP-----SSAHSTTSGRGESTTSRISPGSTE---------ITTLPGS 3874
Query: 2483 PTVSVMLPLHSEQNKSSPDPTSTLSNTVSYERSTDGSFQDRFREFEDSTLKPNRKKPTEN 2542
T + + S PT+TLS S G R ST + P
Sbjct: 3875 TTTPGLSEASTTFYSSPRSPTTTLS-PASMTSLGVGEESTTSRSQPGST--HSTVSPAST 3931
Query: 2543 IIIDLDKEDKDLILTITESTILEILPELTSDKNTIIDIDHTKPVYEDILGMQTDIDTEVP 2602
L +E + + ST + P T+ T + E P
Sbjct: 3932 TTPGLSEESTTVYSSSPGSTETTVFPRSTT----------------------TSVRREEP 3969
Query: 2603 SEPHDSNDESNDDSTQVQEIYEAAVNLSLTEET--FEGSADVLASYTQAT------HDES 2654
+ H S ST E + LTEE+ F GS + AT +ES
Sbjct: 3970 TTFH-----SRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEES 4024
Query: 2655 MTYEDRSQLDHMGF----HFTTGIPAPSTETELDVLLPTATSLP-------IPRKSATVI 2703
T+ S T+G+ ST + L T+LP + KS T
Sbjct: 4025 TTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFY 4084
Query: 2704 PEIEG----IKAEAKALDDMFESSTLSDGQAIADQSEIIP----TLGQFERTQEEYEDKK 2755
+ + E S+ S Q + + P T G + + +
Sbjct: 4085 TSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQG 4144
Query: 2756 HAGPSFQP---EFSSGAEEALVDHTPYLSIATTHLMDQSVTEVPDVMEGSNPPY------ 2806
+ P SS +++ H+ TT L D ++T ++E S P +
Sbjct: 4145 STEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITS--GLVEASTPTHSSTGSL 4202
Query: 2807 YTDTTLAVSTFAKLSSQTPSSPLTIYSGSEASGHTEIPQPSALPGIDVGSSVMSPQDSFK 2866
+T T A ST L ++ T S +S T P + ++V ++ S S
Sbjct: 4203 HTTLTPASSTSTGLQEES----TTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTP 4258
Query: 2867 EIHVNIEATFKPSSEEYLHITEPPSLSPDTKLEPSEDDGKPELLEEMEASPTELIAVEGT 2926
H + +T SEE + P + T L P+ L+ E SP I+ T
Sbjct: 4259 TTHFSASSTTLGRSEESTTVHSSPG-ATGTALFPTR-SATSVLVGEPTTSP---ISSGST 4313
Query: 2927 EILQDFQNKTDGQVSGEAIKMFPTIKTPEA--GTVITTADEIELEGATQWPHSTSASATY 2984
E + T +S ++ + + ++P+ TT+ + E T S T
Sbjct: 4314 ETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTA 4373
Query: 2985 GVEAGVVPWLSPQT--SERPTLSSSPEINP-ETQAALIRGQDSTIAASEQQVAARILDSN 3041
+ +P +S ++ S S+ ++P T A+ + + +T +S +L N
Sbjct: 4374 FPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDN 4433
Query: 3042 DQAT 3045
A+
Sbjct: 4434 TTAS 4437
Score = 135 bits (341), Expect = 5e-31
Identities = 592/2765 (21%), Positives = 917/2765 (33%), Gaps = 492/2765 (17%)
Query: 576 IPEVITVSKTSEDTIHTHLEDLESVSASTTVSPLI--MPDNNGSSMDDWEERQTSGRITE 633
+ E T ++ T TH + S + S + PD +G++ TSGR
Sbjct: 2715 VEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSS-AHSTTSGR--- 2770
Query: 634 EFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRERTETLIPE 693
G+ STT S TEI P S + ST Y S R T TL P
Sbjct: 2771 ---GE--STTSRISPGSTEITTLPGSTTTPGLSEASTTFYSS-------PRSPTTTLSPA 2818
Query: 694 MRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEP-IHVTESSVEMTKSFDFP-- 750
T E E T G T V + LSE V SS T++ FP
Sbjct: 2819 SMTSLGVGE--ESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRS 2876
Query: 751 TLITKLSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEA----------ATV 800
T + EPT A+ TT + E+ TT L + + AT+
Sbjct: 2877 TTTSVRGEEPTTFHSRP----ASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATL 2932
Query: 801 SKWSWDEDNTTSKPLESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDS 860
+ E++TT S+ S + L PA TT G+ G+ PS + E T +P S
Sbjct: 2933 TTADLGEESTT---FPSSSGSTGTTLSPARSTTSGLVGEST--PSRLSPSSTETTTLPGS 2987
Query: 861 -TQKQLEEVTDEDIAAHGKFTIRFQP--TTSTGIAEKSTLRDSTTEEKVPPITSTEGQVY 917
T L E + + P TTS+G++E +S+T P T T
Sbjct: 2988 PTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSE-----ESSTSHSQPGSTHTTA--- 3039
Query: 918 ATMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSST------QEPTTYVDSSH 971
D + +S P +H+S+ A +S ST Q+ TT+ S
Sbjct: 3040 ----------FPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPG 3089
Query: 972 TIPLSVIPKTDW--GVLVPSVPSEDEVLGEPSQDILVIDQTRLEATISPETMRTTKITE- 1028
+++P G++ S P+ L T++P + + + E
Sbjct: 3090 DTETTLLPDDTITSGLVEASTPTHSST-------------GSLHTTLTPASSTSAGLQEE 3136
Query: 1029 GTTQEEFPWKEQTAEKP-----VPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELL-- 1081
TT + +P T P P ST + + + TP + SE+
Sbjct: 3137 STTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVH 3196
Query: 1082 -----TGSERVPVLE----------TTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRI 1126
TG+ P T+P+ + PG+ T + +
Sbjct: 3197 SSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPR 3256
Query: 1127 GPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKTSLE---------- 1176
P +LSP + G S TS P STH T TT S E
Sbjct: 3257 SPDTTLSPASTT---SSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGS 3313
Query: 1177 -DIDLGSG-------------LFEKPKATE--LIEFSTIKVTVPSDITTAFSSVDRLHTT 1220
D L G P +TE L+ +T + T SS HTT
Sbjct: 3314 TDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTT 3373
Query: 1221 SAFKPSSAITKK---------PPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKET 1271
P+ + T++ P D P TT+ + +TSH P++ +
Sbjct: 3374 --LSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSAS 3431
Query: 1272 ETDIDREYFTT---SSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTK--FHPDINVYI 1326
T + R +T SSP AT T P ++ + P ST+ P+ +
Sbjct: 3432 STTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTS 3491
Query: 1327 IEVRENKTGRMSDLSVIGH-PIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYH 1385
E+ T S I P + + +EP S + P + FPD
Sbjct: 3492 GRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPG----STATTHFPDSSTTSGRS 3547
Query: 1386 SEENEEEEEECANATDVTTTPSV-QYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFS 1444
E + A T V S + G+ + + A G + S+ +
Sbjct: 3548 EESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKST 3607
Query: 1445 DSSESDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPE-----------TSEHF 1493
S P +T+ +E + T+ S + +P+ T+ H
Sbjct: 3608 TFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHS 3667
Query: 1494 SGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFPEESSGEIAI 1553
S G D T+ SG++++ S + + + T +S F +ES+ +
Sbjct: 3668 SPGSTDT--TLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALS-FGQESTTFHSS 3724
Query: 1554 DQESQKIAFARATEVTFGEEVEKSTSV---TYTP--TIVPSSASAYVSEEEAVTLIGNPW 1608
+ F +T T VE ST V T +P T+ P+S+++ + E+ +P
Sbjct: 3725 PGSTHTTLFPDST--TSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPA 3782
Query: 1609 PDDLLSTKESWVEATPRQVVELSGS-SSIPITE----GSGEAEEDEDTMF------TMVT 1657
+ S A + S S P T + ++ T+F + T
Sbjct: 3783 STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTT 3842
Query: 1658 DLSQRNTTDTLITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISS 1717
S +TT TSRI S TT+ + P T F S + S
Sbjct: 3843 PSSAHSTTSGRGESTTSRISPGS---TEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLS 3899
Query: 1718 TTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELESPNVATSSDSGTRKSFMSLT 1777
EE TT + +S+ + ES V +SS T + +
Sbjct: 3900 PASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRS 3959
Query: 1778 TPTQSEREMTD---STPVFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFME 1834
T T RE S P T T TE S+ G+ E T P SPAS
Sbjct: 3960 TTTSVRREEPTTFHSRPASTHTTLF-------TEDSTTS--GLTEESTAFPGSPASTQTG 4010
Query: 1835 QGSGEAAAD--PETTTVSSFSLNVEYAIQAEKEVAGT-LSPHVETTFSTEPTGLVLSTVM 1891
+ AD E+TT S S + GT LSP TT +GLV +
Sbjct: 4011 LPATLTTADLGEESTTFPSSSGST-----------GTKLSPARSTT-----SGLVGESTP 4054
Query: 1892 DRVVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPLEEDFSGDFREYSTVSHPIAKE 1951
R+ + T+ + G T L E + + + P + +
Sbjct: 4055 SRLSPSSTETTT-----------------LPGSPTTPSLSE------KSTTFYTSPRSPD 4091
Query: 1952 ETVMMEGSGDAAFRDTQTSPSTVPTSVHISHISDSEGPSSTMVSTSAFPWEEFTS-SAEG 2010
T+ + + + ++ + P S H + DS +TS E TS S++G
Sbjct: 4092 ATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDS-------TTTSGLSQEPTTSHSSQG 4144
Query: 2011 SGEQLVTVSSSVVPVLPSAVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTK 2070
S E ++ S+ L G S+ G D +T+LP + T
Sbjct: 4145 STEATLSPGSTTASSL--------GQQSTTFHSSPG--------DTETTLLPDDTI--TS 4186
Query: 2071 APVEKEEVKVSGTVSTNFPQTIEPAKLWSRQEVNPVRQEIESET--------TSEEQIQE 2122
VE S T S + T + QE + Q S + T+ ++
Sbjct: 4187 GLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEV 4246
Query: 2123 EKSFESPQNSPATEQTIFDSQTFTETELKTTDYSVLTTKKTYSDDKEMKEEDTSLVNMST 2182
++ S +S T S T +E TT +S + T + + + LV T
Sbjct: 4247 STTYHSRPSSTPTTHFSASSTTLGRSEESTTVHS--SPGATGTALFPTRSATSVLVGEPT 4304
Query: 2183 PDPDANGLESYTTLPEAT------EKSHFFLATALVTESIPAEHVVTDSPIKKEESTKHF 2236
P ++G T LP +T EKS F ++ ++ + T S + +E +T H
Sbjct: 4305 TSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS 4364
Query: 2237 -PKGMRPTIQESDTELLFSGLGSGEEVLPTLPTESV-NFTEVEQINNTLYPHTSQVESTS 2294
P M T S T +P + ES + + + TL P ++
Sbjct: 4365 RPGSMHTTAFPSST------------TMPGVSQESTASHSSPGSTDTTLSPGST------ 4406
Query: 2295 SDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVTSTTLIEILSDTGAEGPTVAPLPFSTD 2354
A +GP ++ F S T TTL+ +T A G A P +
Sbjct: 4407 ------------TASSLGP---ESTTFHSSPGSTETTLLP--DNTTASGLLEASTPVHSS 4449
Query: 2355 IGHPQNQTVRWAEEIQTSRPQTITEQDSNKNSSTAEINETTTSSTDFLARAYGFEMAKEF 2414
G P S S+T + TT S + +K+
Sbjct: 4450 TGSPHTTL-------------------SPAGSTTRQGESTTFQS---------WPNSKDT 4481
Query: 2415 VTSAPKPSDLYYEPSGEGSGEVDIVDSFHTSAT-TQATRQESSTTFVSDGSLEKHPEVPS 2473
+ P + + E S G + H SA+ T R E STT S P
Sbjct: 4482 TPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSS---------PV 4532
Query: 2474 AKAVTADGFPTVSVMLPLHSEQNKSSPDPTSTLSNTVSYERSTDGSFQDRFREFEDSTLK 2533
A A T + + L S SSP T T+ S S G E+ST
Sbjct: 4533 ATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRG---------EESTTS 4583
Query: 2534 PNRKKPTENIIIDLDKEDKDLILTITESTILEILPELTSDKNTIIDIDHTKPVYEDILGM 2593
+ T ++ ST ++ E TS ++ T + D
Sbjct: 4584 HSSTTHT---------------ISSAPSTTSALVEEPTSYHSSPGSTATTH--FPD--SS 4624
Query: 2594 QTDIDTEVPSEPHDSNDESNDDSTQVQEIYEAAVNLSLTEETFEGSADVLA----SYTQA 2649
T +E + H S D + + + S T GS + A + T
Sbjct: 4625 TTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPG 4684
Query: 2650 THDESMTYEDR---SQLDHMGFHFTTGIPAPSTETELDVLLPTATSLPIPRKSAT--VIP 2704
++S T+ + H TT + + T + TAT+ P P +S T ++
Sbjct: 4685 LSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATT-PSPARSTTSGLVE 4743
Query: 2705 EIEGIKAEAKALDDMF--ESSTLSDGQAIADQSEIIPTLGQFERTQEEYEDKKHAGPSFQ 2762
E + + M ESST S G+ E ++ + H S
Sbjct: 4744 ESTAYHSSPGSTQTMHFPESSTAS---------------GRSEESRTSHSSTTHTISSPP 4788
Query: 2763 PEFSSGAEEALVDHTPYLSIATTHLMDQSVTEVPDVMEGSNPPYYTDTTLAVSTF-AKLS 2821
S+ EE H+ SIATTH + S T E S + + T ++ A +
Sbjct: 4789 STTSALVEEPTSYHSSPGSIATTHFPESSTTS--GRSEESTASHSSPDTNGITPLPAHFT 4846
Query: 2822 SQTPSSPLTIYSGSEASGHTEIPQPSALPGIDVGSSVMSPQDSFKEIHVNIEATFKPSSE 2881
+ + T + S S T + + PG+ S+++
Sbjct: 4847 TSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSS------------------- 4887
Query: 2882 EYLHITEPPSLSPDTKLEPSEDDGKPELLEEMEASPTELIA-VEGTEILQDFQNKTDGQV 2940
S SPD L P+ + PT L + E T + T +
Sbjct: 4888 ---------SRSPDQTLSPASMTS-----SSISGEPTSLYSQAESTHTTAFPASTTTSGL 4933
Query: 2941 SGEAI----KMFPTIKTPEAGTVITTADEIELEGATQWPHST--SASATYGVEAGVVPWL 2994
S E+ K T T G++ T++ E PHS SA +T + VP L
Sbjct: 4934 SQESTTFHSKPGSTETTLSPGSITTSSFAQEF----TTPHSQPGSALSTVSPASTTVPGL 4989
Query: 2995 SPQTSERPTLSSSPEINPET-----QAALIRGQDST----IAASEQQVAARILDSNDQAT 3045
S E T SSP T I Q ST V L + D
Sbjct: 4990 S---EESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQ 5046
Query: 3046 VNPVEFNTEVATPPFSLLETSNETDFLIGINEESVEGTAIYL-PGPDRCKMNPCLNGGTC 3104
+ ++ AT L S +D L+G E T Y+ P P + P + T
Sbjct: 5047 ESTAFHSSSDATGTTPLPARSTASD-LVG------EPTTFYISPSPTYTTLFPA-SSSTS 5098
Query: 3105 YPTETSYVCTCVPGYSGDQCELD-FDECHSNPCRNGATCVDGFNTFRCLCLPSYVGALCE 3163
TE S P ++ + + C+ G +N +C+C YVG C
Sbjct: 5099 GLTEESTTFHTSPSFTSTIVSTESLETLAPGLCQEGQI----WNGKQCVCPQGYVGYQCL 5154
Query: 3164 QDTET 3168
E+
Sbjct: 5155 SPLES 5159
Score = 125 bits (315), Expect = 5e-28
Identities = 584/2720 (21%), Positives = 897/2720 (32%), Gaps = 414/2720 (15%)
Query: 642 TTPFP-SQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRERTETLIPEMRTDTYT 700
+TP P S E P S K + ST Y S ++ T T +P T +
Sbjct: 608 STPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDT-------THLPASMTSSGV 660
Query: 701 DEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMTKSFDFPTLITKLSAEP 760
E E T G T F G LS+ + SS T + P T S P
Sbjct: 661 SE--ESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGP 718
Query: 761 TEVRDMEEDFTATPG---TTKYDENITTVLLAHGTLSVEAATVSKWSW-DEDNTTSKPLE 816
F + PG TT +N T L ++ V ++T S + +T++ E
Sbjct: 719 EYTT-----FHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGE 773
Query: 817 STE----PSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIP-------DSTQKQL 865
ST PS+ P TT PS T G+ + IP +T +
Sbjct: 774 STTFHSWPSSKDTRPAPPTTTSAFVE-----PSTTSHGSP--SSIPTTHISARSTTSGLV 826
Query: 866 EEVTDEDIAAHGKFTIRF-QPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSA 924
EE T + T+ F + T++G E+ST S+T + ST SA
Sbjct: 827 EESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTT---------SA 877
Query: 925 LGEVEDVDLSKPVSTVP-QFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDW 983
L E S P ST F +S G + S +S D++ TI L
Sbjct: 878 LVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQ----DATGTIVL-------- 925
Query: 984 GVLVPSVPSEDEVLGEPSQDILVIDQTRLEATISPETMRTTKITE-GTTQEEFPWKEQTA 1042
P+ + +LGE + I +E T P + T ++E TT P T
Sbjct: 926 ----PARSTTSVLLGESTTS--PISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATT 979
Query: 1043 EKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKIDHSV 1102
P SS +E+ T + GS +T + P TTP G HS
Sbjct: 980 LSPASTTSSGV--SEESTT---SRSRPGSTHTTA----------FPDSTTTP-GLSRHST 1023
Query: 1103 SYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHIT 1162
T H TL P + + GP Q+ T SS+ ++LSP ST
Sbjct: 1024 -------TSHSSPGSTDTTLLPAS----TTTSGPSQESTTSHSSSGSTDTALSPGSTTAL 1072
Query: 1163 QLMEETT--------TEKTSLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDIT------ 1208
+E+T T T D SG+ E S P+ T
Sbjct: 1073 SFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQG 1132
Query: 1209 --TAFSSVDRLHTTSAFKPSSAI--TKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLE 1264
TAF + T+ PS+A ++ R PG T+ ++ H +T+
Sbjct: 1133 ESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF 1192
Query: 1265 DIVAKETETDIDREYFTTS----------SPPATQPTRPP---TVEDKEAFGPQALSTPQ 1311
+ T + TTS SP +T+ T P T S+P+
Sbjct: 1193 HSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPR 1252
Query: 1312 PPASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLM--A 1369
P +T ++ + V E T S + S SEE+ V+ +
Sbjct: 1253 SPTTTL--SPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGS 1310
Query: 1370 EILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEA 1429
FP ++ E + T + T S T P P + +
Sbjct: 1311 TETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTT-SGLTEESTAFPGSPASTQT 1369
Query: 1430 RRGQFESVA----PSQNFSDSSESDTHPFVIAKTELSTAV-QPNESTETTESLEVTWKP- 1483
+ A S F SS S A++ S V + S + S E T P
Sbjct: 1370 GLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPG 1429
Query: 1484 -ETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTER-DTEVGHQAHEHT---- 1537
T P SE + F T P + A + V+E T HT
Sbjct: 1430 SPTTPSLSE-----KSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFP 1484
Query: 1538 ----------EPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEE-------------- 1573
EP + + S E + S + TF
Sbjct: 1485 DSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTI 1544
Query: 1574 ----VEKSTSV-----TYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLST-KESWVEAT 1623
VE ST + T+ P+S+++ +EE+ T WP +T A
Sbjct: 1545 TSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTF--QSWPSSSDTTPSPPGTTAA 1602
Query: 1624 PRQVVEL--SGSSSIPITEGSGEA-----EEDEDTMF-----TMVTDLSQRNTTDTLITL 1671
P +V S SS P T S + E+ T+ T R+ T L+
Sbjct: 1603 PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE 1662
Query: 1672 DTSRIITESFFEVPA----TTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKE 1727
T+ I+ E A TT +SE+ T F S + + S
Sbjct: 1663 PTTSPISSGSTETTALPGSTTTAGLSEK------STTFYSSPRSPDTTLSPASTTSSGVS 1716
Query: 1728 EEGTTGTASTFEVYSSTQRSDQLILPFELESPNVATSSDSGTRKSFMSLTTPTQS----E 1783
EE TT + +++ + ES A+ S G+ + +S + T S E
Sbjct: 1717 EESTTSHSRPGSTHTTAFPGSTTMPGVSQES--TASHSSPGSTDTTLSPGSTTASSLGPE 1774
Query: 1784 REMTDSTPVFTETNTLEN-------LGAQTTEHSSIHQP--GVQEGLTTLPRSPASVFME 1834
S+P TET L + L A T HSS P + +T + ++ F
Sbjct: 1775 STTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQS 1834
Query: 1835 QGSGEAAADPETTTVSSFSLNVEYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRV 1894
S + TT S+F VE + + + T + H + +T +TV
Sbjct: 1835 WPSSKDTMPAPPTTTSAF---VELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSP 1891
Query: 1895 VAENITQTSREIVISERLGEPNYGAEIRGFSTGFPLEEDFSGDFR-EYSTVSHPIAKEET 1953
VA T + S + E G + E + R E S SH + T
Sbjct: 1892 VATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHS-STTHT 1950
Query: 1954 VMMEGSGDAAFRDTQTSPSTVPTSVHISHISDSEGPSS-TMVSTSAFPWEEFTSS--AEG 2010
+ S +A + TS + P S +H DS S + ST++ ++ T +
Sbjct: 1951 ISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPA 2010
Query: 2011 SGEQLVTVSSSVVPVLPSAVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTK 2070
V + S + S + + S GL E T RS + T
Sbjct: 2011 RSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTS 2070
Query: 2071 APVEKEEV----KVSGTVSTNFPQTIEPAKLWSRQEVNPVRQEIESETT----SEEQIQE 2122
+ V +E + T +T FP + L SR ++TT S
Sbjct: 2071 SGVSEESTTSHSRPGSTHTTAFPDSTTTPGL-SRHSTTSHSSPGSTDTTLLPASTTTSGP 2129
Query: 2123 EKSFESPQNSPATEQTIFDSQTFT-------ETELKTTDYSVLTTKKTYSDDKEMKEEDT 2175
+ + +SP + T + T T ++ S TT S E +
Sbjct: 2130 SQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAS 2189
Query: 2176 SLVNMSTPDPDANGLESYTTLPEATEKSHFFLATALVTESIPAEHVVTDSPIKKEES--- 2232
+ V+ ST P + +T P +S F T + P+ +P+++ +
Sbjct: 2190 TRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHR 2249
Query: 2233 ------TKHFP---------------------KGMRPTIQESDT----ELLFSGLGSGEE 2261
T HFP G P+ S T E S + G
Sbjct: 2250 SPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGST 2309
Query: 2262 VLPTLPTESVN----------FTEVEQINNTLYPHT------SQVESTSSDKIEDFNRME 2305
+ TLP + ++ TL P + + +TS + +
Sbjct: 2310 EITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTV 2369
Query: 2306 NVAKEVGPLVSQ--TDIFEGSGSVTSTTLIEILSDTGAEG--PTV---APLPFSTDIGHP 2358
+ A P +S+ T ++ S T TT+ T G PT P T +
Sbjct: 2370 SPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTE 2429
Query: 2359 QNQTVRWAEE----------IQTSRPQTITEQDSNKNSSTAEINETTTSSTDFLARAYGF 2408
+ T EE QT P T+T D + S+T + +T +T AR+
Sbjct: 2430 DSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTS 2489
Query: 2409 EMAKEFVTSAPKPSD-----LYYEPSGEGSGEVDIVDSFHTS-ATTQATRQESSTTF--V 2460
+ E S PS L P+ E +F+TS + AT ++TT V
Sbjct: 2490 GLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKS--TTFYTSPRSPDATLSPATTTSSGV 2547
Query: 2461 SDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSEQNKSSPDPTSTLSNTVSYERSTDGSF 2520
S+ S H + P + TA T + L HS + SSP T T + +T G
Sbjct: 2548 SEESSTSHSQ-PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT--TLLPASTTTSGPS 2604
Query: 2521 QDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDLILTITESTILEILPELT--------- 2571
Q+ P + +E + ST + P+ T
Sbjct: 2605 QESTTSHSSPGSTDTALSPGSTTALSFGQE-STTFHSSPGSTHTTLFPDSTTSSGIVEAS 2663
Query: 2572 --------SDKNTIIDIDHTKPVYEDILGMQTDIDTEVPSEPHDSNDESNDDSTQVQEIY 2623
S + T+ T P + G T T P+ H + + + V+E
Sbjct: 2664 TRVHSSTGSPRTTLSPASSTSP---GLQGESTTFQTH-PASTHTTPSPPSTATAPVEE-- 2717
Query: 2624 EAAVNLSLTEETFEGSADVL---ASYTQATHDESMTY----EDRSQLDHMGFHFTTGIPA 2676
S T GS AS T + H E T D S H TT
Sbjct: 2718 ------STTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRG 2771
Query: 2677 PSTETELDVLLPTATSLPIPRKSATVIPEIEGIKAEAKALDDMFESSTLSDGQAIADQSE 2736
ST + + T+LP +T P + +EA F SS S ++ S
Sbjct: 2772 ESTTSRISPGSTEITTLP----GSTTTPGL----SEAST---TFYSSPRSPTTTLSPASM 2820
Query: 2737 IIPTLGQFERTQEEYEDKKHAGPSFQPEFSSGAEEALVDHTPYLSIATTHLMDQSVTEVP 2796
+G+ T H+ + P ++ TP LS +T + S P
Sbjct: 2821 TSLGVGEESTTSRSQPGSTHS--TVSPASTT---------TPGLSEESTTVYSSS----P 2865
Query: 2797 DVMEGSNPPYYTDTTLAVSTFAKLSSQTPSSPLTIYS-GSEASGHTEIPQPSALPGIDVG 2855
E + P T T++ S+ S+ T+++ S SG TE + +A PG
Sbjct: 2866 GSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTE--ESTAFPGSPAS 2923
Query: 2856 SSVMSPQDSFKEIHVNIEATFKPSSEEYLHITEPPSLSPDTKLEPSEDDGKPELLEEMEA 2915
+ P + + E+T PSS T P+ S + L + +
Sbjct: 2924 TQTGLPA-TLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSR------LSP 2976
Query: 2916 SPTELIAVEGTEILQDFQNKTDGQVSGEAIKMFPTIKTPEA--GTVITTADEIELEGATQ 2973
S TE + G + T +S ++ + + ++P+A TT+ + E +T
Sbjct: 2977 SSTETTTLPG--------SPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTS 3028
Query: 2974 WPHSTSASATYGVEAGVVPWLS--PQTSERPTLSSSPEINPETQAALIRGQDSTIAASEQ 3031
S T ++ LS P S S+ ++P + A GQ ST S
Sbjct: 3029 HSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSP 3088
Query: 3032 QVAARILDSNDQATVNPVEFNTEVATPPFSLLET-SNETDFLIGINEESVEGTAIYLPGP 3090
L +D T VE +T + SL T + + G+ EES + P
Sbjct: 3089 GDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEES----TTFQSWP 3144
Query: 3091 DRCKMNPCLNGGTCYPTETS 3110
P G T P E S
Sbjct: 3145 SSSDTTPSPPGTTAAPVEVS 3164
Score = 115 bits (287), Expect = 1e-24
Identities = 544/2585 (21%), Positives = 853/2585 (32%), Gaps = 359/2585 (13%)
Query: 641 STTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRERTETLIPEMRTDTYT 700
+TT S+ T P S D+ L +T S ++ +H R I + T
Sbjct: 271 TTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMP 330
Query: 701 DEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMTKSFDFPTLITKLSAEP 760
QE G T+ + G +SL SS TK+ P T ++
Sbjct: 331 GVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTT--TSGL 388
Query: 761 TEVRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEAATVSKWSWDED------NTTSK- 813
E T +P TT + T T E T W +D TTS
Sbjct: 389 LEASTPVHSSTGSPHTTLSPSSST-------THEGEPTTFQSWPSSKDTSPAPSGTTSAF 441
Query: 814 -PLESTEPSASSKLP----PALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEV 868
L +T S+ S P A TT+G + + + S A +T +EE
Sbjct: 442 VKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEES 501
Query: 869 TDEDIAAHGKFTIRF--QPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALG 926
T + T+ F TTS E +T STT K ST + T S+LG
Sbjct: 502 TAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTK-SSTPSTTAALAHTSYHSSLG 560
Query: 927 EVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSSTQEP----TTYVDSSHTIPLSV----- 977
E F +S + G + S +S P TT + + T + V
Sbjct: 561 STE----------TTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTP 610
Query: 978 IPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRL-EATISPETMRTTKIT-EGTTQEEF 1035
P + + ++P G + R + T P +M ++ ++ E TT
Sbjct: 611 SPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSR 670
Query: 1036 PWKEQTAEKP----VPALSSTAWTPKEAVTPLDEQEGDGSAYTVS-EDELLTGSERVPVL 1090
P T P +P LS + + P D GS S E T R
Sbjct: 671 PGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGST 730
Query: 1091 ETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTP-----RIGPKVSLSPGPEQKYETEGS 1145
ETT + + ++ H TL+P R G + P K
Sbjct: 731 ETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAP 790
Query: 1146 STT-------GFTSSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATELIEFST 1198
TT TS SP S T + +TT ++ + P +T+ + F
Sbjct: 791 PTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGL----VEESTTYHSSPGSTQTMHFPE 846
Query: 1199 IKVTVPSDITTAFSSVDRLHT-TSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSH 1257
T + S HT +SA +SA+ ++P PG T+ ++
Sbjct: 847 SDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR 906
Query: 1258 VPPTTLEDIVAKETETDIDREYFTTSSPPATQPTRPPTVEDKEAFG-PQALSTP-QPPAS 1315
+T T T + TTS T P + E P + +TP S
Sbjct: 907 SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERS 966
Query: 1316 TKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSES--KEDEPCSEETDPVHDLMAEILP 1373
T FH + +S S + ES P S T
Sbjct: 967 TTFHSS--------PRSPATTLSPASTTSSGVSEESTTSRSRPGSTHT-----------T 1007
Query: 1374 EFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQ 1433
FPD + +TD T P+ +G +T +
Sbjct: 1008 AFPD--STTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTD---- 1061
Query: 1434 FESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTE------TTESLEVTWKPETYP 1487
+++P + S ++ F T + P+ +T +T T P T
Sbjct: 1062 -TALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL 1120
Query: 1488 ETSEHFS---GGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFP 1544
+ S GE F T P V E T + + P + FP
Sbjct: 1121 SPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTT---YHRSPGSTPTTHFP 1177
Query: 1545 EESSG----------EIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTP-TIVPSSASA 1593
S+ + D + A +T GE S T T +P S +
Sbjct: 1178 ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTT 1237
Query: 1594 YVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELS-GSSSIPITEGSGEAEEDEDTM 1652
E + T +P + +P + L G S G
Sbjct: 1238 PGLSEASTTFYSSP--------RSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 1289
Query: 1653 FTMVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIYPVSEQPSAK-VVPTKFVSETDT 1711
T LS+ +TT +SR TE TT++P S S PT F S +
Sbjct: 1290 STTTPGLSEESTT----VYSSSRGSTE-------TTVFPHSTTTSVHGEEPTTFHSRPAS 1338
Query: 1712 SEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELESPNV--------AT 1763
+ T E+ T+G + + S Q LP L + ++ ++
Sbjct: 1339 THTTLFT--------EDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSS 1390
Query: 1764 SSDSGTRKS-FMSLTTPTQSEREMTDSTPVFTETNTLENLGAQTTEHSSIHQPGVQEGLT 1822
S +GT+ S S T+ E + +P TET TL G+ TT P + E T
Sbjct: 1391 SGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLP--GSPTT-------PSLSEKST 1441
Query: 1823 TL---PRSP------------------ASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQ 1861
T PRSP ++ + GS A P++TT S S +
Sbjct: 1442 TFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHS 1501
Query: 1862 AEKEVAGTLSP---------HVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERL 1912
++ TLSP TTF + P + + D + + + S
Sbjct: 1502 SQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEAS--------- 1552
Query: 1913 GEPNYGAEIRGFSTGFPLEEDFSGDFREYSTV-SHPIAKEETVMMEGSGDAAFRDTQT-- 1969
P + + +T P +G E +T S P + + T G+ A + T
Sbjct: 1553 -TPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYH 1611
Query: 1970 -SPSTVPTSVHISHISDSEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPS 2028
PS+ PT+ H S S + G S + + P T+ V V + S
Sbjct: 1612 SRPSSTPTT-HFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISS 1670
Query: 2029 AVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNF 2088
+ + S GL E T RS + T + V +E T S +
Sbjct: 1671 GSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEE-----STTSHSR 1725
Query: 2089 PQTIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTET 2148
P + + V QE T S + SP ++ T ++ T +
Sbjct: 1726 PGSTHTTAFPGSTTMPGVSQE---STASHSSPGSTDTTLSPGST--TASSLGPESTTFHS 1780
Query: 2149 ELKTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATE-----KS 2203
+T+ ++L T S L+ STP + G +TTL A +S
Sbjct: 1781 SPGSTETTLLPDNTTAS----------GLLEASTPVHSSTG-SPHTTLSPAGSTTRQGES 1829
Query: 2204 HFFLATALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVL 2263
F + +++PA T S + +T H PT S + + LG EE
Sbjct: 1830 TTFQSWPSSKDTMPAPPTTT-SAFVELSTTSHGSPSSTPTTHFSASS---TTLGRSEE-- 1883
Query: 2264 PTLPTESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEG 2323
+ +V+ + V S ST+S +E E+ A P +QT F
Sbjct: 1884 ----STTVHSSPVATATT-----PSPARSTTSGLVE-----ESTAYHSSPGSTQTMHFPE 1929
Query: 2324 SGSVTSTTLIEILSDTGAEGPTVAPLPFSTD--IGHPQNQTVRWAEEIQTSRPQTITEQD 2381
S S S E + + T++ P +T + P + T P + T
Sbjct: 1930 S-STASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSG 1988
Query: 2382 SNKNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPSDLYYEPSGEGS----GEVD 2437
++ S+ + ++ T + AR+ + E TS P S + GS G +
Sbjct: 1989 RSEESTASHSSQDATGTIVLPARSTTSVLLGESTTS-PISSGSMETTALPGSTTTPGLSE 2047
Query: 2438 IVDSFHTSATTQATRQESSTTF---VSDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSE 2494
+FH+S + AT ++T VS+ S H P + TA T + L HS
Sbjct: 2048 KSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSR-PGSTHTTAFPDSTTTPGLSRHST 2106
Query: 2495 QNKSSPDPTSTLSNTVSYERSTDGSFQDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDL 2554
+ SSP T T + +T G Q+ P + +E
Sbjct: 2107 TSHSSPGSTDT--TLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQE-STT 2163
Query: 2555 ILTITESTILEILPELT-----------------SDKNTIIDIDHTKPVYEDILGMQTDI 2597
+ ST + P+ T S + T+ T P G+Q +
Sbjct: 2164 FHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP------GLQGE- 2216
Query: 2598 DTEVPSEPHDSNDESNDDSTQVQEIYEAAVNLSLTEETFEGSADVL---ASYTQATHDES 2654
T + P ++ + ST A V S T GS AS T + H E
Sbjct: 2217 STAFQTHPASTHTTPSPPSTAT-----APVEESTTYHRSPGSTPTTHFPASSTTSGHSEK 2271
Query: 2655 MTY----EDRSQLDHMGFHFTTGIPAPSTETELDVLLPTATSLPIPRKSATVIPEIEGIK 2710
T D S H TT ST + + T+LP +T P +
Sbjct: 2272 STIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLP----GSTTTPGL---- 2323
Query: 2711 AEAKALDDMFESSTLSDGQAIADQSEIIPTLGQFERTQEEYEDKKHAGPSFQPEFSSG-A 2769
+EA F SS S ++ S +G+ T H+ S + G +
Sbjct: 2324 SEAST---TFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLS 2380
Query: 2770 EEALVDHTPYLSIATTHLMDQSVTEVPDVMEGSNP------PYYTDTTLAV--STFAKLS 2821
EE+ ++ T + ++ T + G P P T TTL ST + L+
Sbjct: 2381 EESTTVYSSSPGSTETTVFPRTPT---TSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLT 2437
Query: 2822 SQTPSSPLTIYSGSEASGHTEIPQPSALPGIDVGSSVMSPQDSFKEIHVNIEATFKPSSE 2881
++ T + GS AS T + P+ L D+G + S + + ++
Sbjct: 2438 EES-----TAFPGSPASTQTGL--PATLTTADLGEESTTFPSSSGSTGTTLSPA-RSTTS 2489
Query: 2882 EYLHITEPPSLSPDTKLEPSEDDGKPELLEEMEASPTELIAVEGTEILQDFQNKTDGQVS 2941
+ + P LSP + E + G P E S T + + T VS
Sbjct: 2490 GLVGESTPSRLSP-SSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVS 2548
Query: 2942 GEAIKMFPTIKTPEAGTVITTA--DEIELEGATQWPHSTSASATYG-VEAGVVP---WLS 2995
E+ + + G+ TTA D G ++ HST++ ++ G + ++P S
Sbjct: 2549 EES-----STSHSQPGSTHTTAFPDSTTTPGLSR--HSTTSHSSPGSTDTTLLPASTTTS 2601
Query: 2996 PQTSERPTLSSSP-----EINPETQAALIRGQDSTIAASEQQVAARILDSNDQATVNPVE 3050
+ E T SSP ++P + AL GQ+ST S L + + VE
Sbjct: 2602 GPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVE 2661
Query: 3051 FNTEV 3055
+T V
Sbjct: 2662 ASTRV 2666
Score = 80.5 bits (197), Expect = 3e-14
Identities = 327/1511 (21%), Positives = 505/1511 (33%), Gaps = 226/1511 (14%)
Query: 1687 TTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQR 1746
TT++P S FV E TS I+S ++E T G + + S+ R
Sbjct: 236 TTLFPSHSATSV------FVGEPKTSP-ITSASMETTALPGSTTTAGLSEKSTTFYSSPR 288
Query: 1747 SDQLILPFELESPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTETNTLENLGAQT 1806
S T S + T S +S + T R T F ++ T+ + ++
Sbjct: 289 SPD------------RTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQES 336
Query: 1807 TEHSSIHQPGVQEGL----TTLPRS--PASVFMEQGSGEAAAD--PETTTVSSFSLNVEY 1858
T SI PG + TT P S P S G P+ TT S
Sbjct: 337 TASHSI--PGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTP 394
Query: 1859 AIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYG 1918
+ TLSP TT EPT S + + + T+ V +L +
Sbjct: 395 VHSSTGSPHTTLSPSSSTTHEGEPTTFQ-SWPSSKDTSPAPSGTTSAFV---KLSTTYHS 450
Query: 1919 AEIRGFSTGFPLEEDFSGDFREYSTV-SHPIAKEETVMMEGSGDAAFRDTQTSPSTVPTS 1977
+ +T F G E + V S P+A T S + + T+ P S
Sbjct: 451 SPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGS 510
Query: 1978 VHISHISDSEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQKFSGTA 2037
H +S S+ G E+ T S S + A
Sbjct: 511 TQTMHFPES-------------------STTSGHSEESATFHGSTTHTKSSTPSTTAALA 551
Query: 2038 SSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQTIEPAKL 2097
+ LG T + D ++ + G + +T P P+ L
Sbjct: 552 HTSYHSSLGSTETTHFRD-------SSTISGRSEESKASHSSPDAMATTVLPAGSTPSVL 604
Query: 2098 WSRQEVNPVRQ------EIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTETELK 2151
+P+ + TT ++ +F S SP T + +E
Sbjct: 605 VGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEES 664
Query: 2152 TTDYSVLTTKKTYSDDKE-----MKEEDTSLVNMSTPDPDANGLE-----------SYTT 2195
TT +S + T + + +E T+ + S+P P L YTT
Sbjct: 665 TTSHSRPGSTHTTAFPGSTTMPGLSQESTA--SHSSPGPTDTTLSPGSTTASSLGPEYTT 722
Query: 2196 L---PEATEKSHF---FLATALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDT 2249
P +TE + A+ L+ S+P H T SP T P G ES T
Sbjct: 723 FHSRPGSTETTLLPDNTTASGLLEASMPV-HSSTRSP-----HTTLSPAGSTTRQGESTT 776
Query: 2250 ELLFSGLGSGEEVLPTLPTESVNFTEVEQINN---TLYPHTS-QVESTSSDKIEDFNRME 2305
F S ++ P PT + F E ++ + P T ST+S +E E
Sbjct: 777 ---FHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVE-----E 828
Query: 2306 NVAKEVGPLVSQTDIFEGSGSVTSTTLIEILSDTGAEGPTVAPLPFSTD--IGHPQNQTV 2363
+ P +QT F S + TS E + + T++ P +T + P +
Sbjct: 829 STTYHSSPGSTQTMHFPESDT-TSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHS 887
Query: 2364 RWAEEIQTSRPQTITEQDSNKNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPSD 2423
T P + T ++ S+ + ++ T + AR+ + E TS P S
Sbjct: 888 SPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTS-PISSG 946
Query: 2424 LYYEPSGEGS----GEVDIVDSFHTSATTQATRQESSTTFVSDGSLEKHPEVPSAKAVTA 2479
+ GS G + +FH+S + AT ++T S S E +
Sbjct: 947 SMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHT 1006
Query: 2480 DGFP--TVSVMLPLHSEQNKSSPDPTSTLSNTVSYERSTDGSFQDRFREFEDSTLKPNRK 2537
FP T + L HS + SSP T T S +T G Q+ S
Sbjct: 1007 TAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAS--TTTSGPSQESTTSHSSSGSTDTAL 1064
Query: 2538 KPTENIIIDLDKEDKDLILTITESTILEILPELT-----------------SDKNTIIDI 2580
P + +E ST + P+ T S + T+
Sbjct: 1065 SPGSTTALSFGQESTTFHSN-PGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPA 1123
Query: 2581 DHTKPVYEDILGMQTDIDTEVPSEPHDSNDESNDDSTQVQEIYEAAVNLSLTEETFEGSA 2640
T P G+Q + T + P ++ + ST + E S T GS
Sbjct: 1124 SSTSP------GLQGE-STAFQTHPASTHTTPSPPSTATAPVEE-----STTYHRSPGST 1171
Query: 2641 DVL---ASYTQATHDESMTY----EDRSQLDHMGFHFTTGIPAPSTETELDVLLPTATSL 2693
AS T + H E T D S H TT ST + + T+L
Sbjct: 1172 PTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTL 1231
Query: 2694 PIPRKSATVIPEIEGIKAEAKALDDMFESSTLSDGQAIADQSEIIPTLGQFERTQEEYED 2753
P +T P + +EA F SS S ++ S +G+ T
Sbjct: 1232 P----GSTTTPGL----SEASTT---FYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG 1280
Query: 2754 KKHAGPSFQPEFSSG-AEEALVDHTPYLSIATTHLMDQSVTEVPDVMEGSNP------PY 2806
H+ S + G +EE+ ++ T + S T + G P P
Sbjct: 1281 STHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTS---VHGEEPTTFHSRPA 1337
Query: 2807 YTDTTLAV--STFAKLSSQTPSSPLTIYSGSEASGHTEIPQPSALPGIDVGSSVMSPQDS 2864
T TTL ST + L+ ++ T + GS AS T +P + L D+G
Sbjct: 1338 STHTTLFTEDSTTSGLTEES-----TAFPGSPASTQTGLP--ATLTTADLGE-------- 1382
Query: 2865 FKEIHVNIEATFKPSSEEYLHITEPPSLSPDTKLEPSEDDGKPELLEEMEASPTELIAVE 2924
E+T PSS S S TKL P+ + E++P+ L +
Sbjct: 1383 --------ESTTFPSS----------SGSTGTKLSPARSTTSGLV---GESTPSRL-SPS 1420
Query: 2925 GTEILQDFQNKTDGQVSGEAIKMFPTIKTPEA--GTVITTADEIELEGATQWPHSTSASA 2982
TE + T +S ++ + + ++P+A TT+ + E +T S
Sbjct: 1421 STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHT 1480
Query: 2983 TYGVEAGVVPWLS--PQTSERPTLSSSPEINPETQAALIRGQDSTIAASEQQVAARILDS 3040
T ++ LS P TS S+ ++P + A GQ ST S L
Sbjct: 1481 TAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP 1540
Query: 3041 NDQATVNPVEFNTEVATPPFSLLET-SNETDFLIGINEESVEGTAIYLPGPDRCKMNPCL 3099
+D T VE +T + SL T + + G+ EES + P P
Sbjct: 1541 DDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEES----TTFQSWPSSSDTTPSP 1596
Query: 3100 NGGTCYPTETS 3110
G T P E S
Sbjct: 1597 PGTTAAPVEVS 1607
>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 125 bits (315), Expect = 5e-28
Identities = 299/1401 (21%), Positives = 475/1401 (33%), Gaps = 88/1401 (6%)
Query: 1093 TPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPR-IGPKVSLSPGPEQKYETEGSSTTGFT 1151
+P G VS +T E T++ G + G E T GS TT
Sbjct: 49 SPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT-V 107
Query: 1152 SSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDITTAF 1211
S +T ++ + ETTT T+ + + S + + T TTA
Sbjct: 108 SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAA 167
Query: 1212 SSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKET 1271
S+ TT S IT G ETT+ + G T+ V T E A
Sbjct: 168 STTGSEMTTVFTAGSETITPSTA------GSETTT-VSTAGSETTTVSTTGSETTTASTA 220
Query: 1272 ETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRE 1331
++ S T A ST +T F D
Sbjct: 221 HSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTG 280
Query: 1332 NKTGRMSDLS---VIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEE 1388
+T S + + SE+ ET V +E+ F E +
Sbjct: 281 FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET--IRAST 338
Query: 1389 NEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSE 1448
E + TTT S+ G T E A E+ S ++ SE
Sbjct: 339 VGSETTTVSTTGSETTTASIM---GSETSTDSTTGSETTTASTEGSETTTAS---TEGSE 392
Query: 1449 SDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHE 1508
+ T ++T + +T TE E+T T ET+ + G + E
Sbjct: 393 ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452
Query: 1509 EFESGTAKKGAESVTER--DTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARAT 1566
+ T +VT +T+ + T S E++ I ++ A +
Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-ASTEGS 511
Query: 1567 EVTFGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQ 1626
E T + T ++ S SE V+ G L T + E +
Sbjct: 512 ETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG-------LETTTTSTEGSEMT 564
Query: 1627 VVELSGS-SSIPITEGSGE-AEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEV 1684
V +G+ ++ TEGSG A + T V+ NTT + +T+ T
Sbjct: 565 TVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETT 624
Query: 1685 PATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEG---TTGTASTFEVY 1741
A+T + S + T VS TD+ + STT E+ EG TT +A+ E
Sbjct: 625 TASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684
Query: 1742 SSTQRSDQLILPFE-LESPNVATSSDSGTRKSF--MSLTTPTQSEREMTDSTPVFTETNT 1798
ST+ S + E+ V+T+ T S +TT + + E T ++ +ET T
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT 744
Query: 1799 LENLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFS--LNV 1856
G++TT S+ T+ + AS+ + + + ETT VS+ S +
Sbjct: 745 ASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT 804
Query: 1857 EYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPN 1916
+ +E +A T + T + + ST T+ S S E
Sbjct: 805 VFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETT 864
Query: 1917 YGA-EIRGFSTGFPLEED---FSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPS 1972
+ E +T + + S + E +T S ++ T EGS T + +
Sbjct: 865 TASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETT 924
Query: 1973 TVPTSVHISHISDSEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQK 2032
T T + + +EG T VST+ E T SAEGS VT S +A +
Sbjct: 925 TASTEGSETTTASTEGSELTTVSTTGS--ETITVSAEGSETTTVTTMGSETTTASTAGSE 982
Query: 2033 FS--GTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQ 2090
+ TA S E + + T GT+ + E + TV+T +
Sbjct: 983 TTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE 1042
Query: 2091 TIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTETEL 2150
T A + E E SETT+ E + S + T + S T T +
Sbjct: 1043 T--TAVYTTGSETTTTSTE-GSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTA 1099
Query: 2151 --KTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATEKSHFFLA 2208
+TT + +K T + + + S + T G E T +E +
Sbjct: 1100 GSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTI 1159
Query: 2209 TALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLPT 2268
+ T S A T + + E+T G T S GS T +
Sbjct: 1160 GSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTA--------STAGSETTTASTAGS 1211
Query: 2269 ESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFE-GSGSV 2327
E+ + NT S+ + SS E N A +G S+T I S
Sbjct: 1212 ETTTASTSGSETNTACTTGSETSTPSSAGSE-----TNTAFIIG---SETTIASTASLEP 1263
Query: 2328 TSTTLIEILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSNKNSS 2387
T+T+L TG+E TV+ + + TV + T + +N S
Sbjct: 1264 TATSL------TGSETTTVS---ITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1314
Query: 2388 TAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPS--DLYYEPSGEGS---GEVDIVDSF 2442
T +++ + A G +F SA + + SG G+ G +
Sbjct: 1315 GTRTTGTRLTASSSVTMAPGM----DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAH 1370
Query: 2443 HTSATTQATRQESSTTFVSDG 2463
TT +TR+ +S+TF G
Sbjct: 1371 GVRTTTGSTREPTSSTFQETG 1391
Score = 102 bits (254), Expect = 6e-21
Identities = 284/1387 (20%), Positives = 460/1387 (33%), Gaps = 131/1387 (9%)
Query: 566 SDESTLIFDQIPEVITVSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGS-----SMD 620
S E+T+ T S T +T ++ E+ +AST S P GS S+
Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61
Query: 621 DWEERQTSGRITEEFLGKYL---STTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQ 677
E TS +E +TT + T + + + G T + ++
Sbjct: 62 GSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMG 121
Query: 678 TEMTHR----RERTETLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSL--- 730
+E T E T T T T + E T +T +G +++T
Sbjct: 122 SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG 181
Query: 731 SEPIHVTESSVEMTKSFDFPTLITKLSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAH 790
SE I + + E T + T +S +E + T + T V A
Sbjct: 182 SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241
Query: 791 GTLSVEAA----TVSKWSWDEDNTTSKPLESTEPSASSKLPPALLTTVGMNGKDKDIPSF 846
+V A T + E NT T ++++ +T G P+
Sbjct: 242 SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSE------PTM 295
Query: 847 TEDGADEFTLI----PDSTQKQLEEVTDEDIAAHGKFTIRFQPTTSTGIAEKSTLRDSTT 902
E T+ P++T+ + A G TIR S +T ++TT
Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTT 355
Query: 903 EEKVPPITSTEGQVYATMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSSTQE 962
+ TST+ + GS + ST T+ EG + S+T
Sbjct: 356 ASIMGSETSTD-----STTGSE---------TTTASTEGSETTTASTEGSEATTVSTTGS 401
Query: 963 PTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLE-ATISPETM 1021
TT V + + + + V + E +I + + E T S E
Sbjct: 402 ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS 461
Query: 1022 RTTKITEGTTQEEFPW---KEQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSED 1078
TT +T ++ + + E T ++T +T T + + +A + +
Sbjct: 462 ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGS 521
Query: 1079 ELLT----GSERVPVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSP 1134
E+ T GSE V T G +VS T + E+ T VS +
Sbjct: 522 EMTTVSTEGSENTTVSTT---GSETTTVSTTGLETTTTSTEGSEMTT--------VSTTG 570
Query: 1135 GPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATELI 1194
TEGS TT +++ S +T T E TT E + E A+
Sbjct: 571 AETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTS 630
Query: 1195 EFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGES 1254
+T T S+ TT + TT + + T I G ETT+ E+
Sbjct: 631 SETTTASTEGSETTT-------VSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSET 683
Query: 1255 T--SHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQP 1312
T + TT I ET TT++ ++ E +
Sbjct: 684 TVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETT 743
Query: 1313 PASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMAEIL 1372
AST+ + S + + + SE+ ET V +++
Sbjct: 744 TASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMT 803
Query: 1373 PEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRG 1432
F + E + + +E A + + + + G TT E +E
Sbjct: 804 TVFTENSETTIASTTASETTTVSTAGSETIPASTA-----GSETTTTT--STEGSETTTA 856
Query: 1433 QFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEH 1492
E + ++SSE+ T +T + +T +TE E T T E SE
Sbjct: 857 STEGSETTTASTESSETTT----------ATTIGSETTTASTEGSETT---TTSTEGSE- 902
Query: 1493 FSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFPEESSGEIA 1552
T E E T T TE TE L ++G
Sbjct: 903 ---------TTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSET 953
Query: 1553 IDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSAS----AYVSEEEAVTLIGNPW 1608
I ++ T T G E +++ T V ++ S A + E T+
Sbjct: 954 ITVSAE--GSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1011
Query: 1609 PDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTDTL 1668
+ST T + GS + +T E T T ++ + T T+
Sbjct: 1012 ETTTVST-----TGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTV 1066
Query: 1669 ITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEE 1728
T S T S ++ TT VS S + SET T S T E
Sbjct: 1067 STTG-SETTTASTADLETTT---VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSE 1122
Query: 1729 EGTTGTASTFEVYSSTQRSDQ-LILPFELESPNVAT-SSDSGTRKSFMSLTTPTQSE-RE 1785
T T S+ +ST S+ + E+ V+T S++ T + S T T +E E
Sbjct: 1123 ATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSE 1182
Query: 1786 MTDSTPVFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPE 1845
T ++ +ET T G++TT S+ G + + S + GS E
Sbjct: 1183 TTTASTAGSETTTASTAGSETTTAST---AGSETTTASTSGSETNTACTTGS-------E 1232
Query: 1846 TTTVSS--FSLNVEYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTS 1903
T+T SS N + I +E +A T S T T +S A + T +S
Sbjct: 1233 TSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSS 1292
Query: 1904 REIVISE 1910
V+++
Sbjct: 1293 TTFVLTK 1299
Score = 100 bits (250), Expect = 2e-20
Identities = 275/1346 (20%), Positives = 455/1346 (33%), Gaps = 156/1346 (11%)
Query: 522 TARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVIT 581
TA M T S + + TG + E T + S E+T+ E T
Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146
Query: 582 VSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGKYLS 641
VS +T + D E+ +ASTT S + GS IT G +
Sbjct: 147 VSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSE-----------TITPSTAGSETT 195
Query: 642 TTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTH-RRERTETLIPEMRTDTYT 700
T T + T ++ +E T +ET + ++T
Sbjct: 196 TVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTA 255
Query: 701 DEIQEEITKSPFM--GKTEEEVFSGMK---LSTSLSEPIHVTESSVEMTKSFDFPTLITK 755
++ T + F KT +G + ST+ SEP + E T + TK
Sbjct: 256 ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315
Query: 756 LSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPL 815
+S +EV + + T + TTV + + S+ S D +
Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 375
Query: 816 ESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDEDIAA 875
STE S + TT G + S T ++ T E ++ +
Sbjct: 376 ASTEGSET--------TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVS 427
Query: 876 HGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSK 935
T F+ TT++ E S + ++T + STEG T+ + +K
Sbjct: 428 ----TTVFETTTAS--TEGSEITIASTSDSETTTASTEGSETTTVTTAG-------SETK 474
Query: 936 PVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDE 995
T T+ GL + + TT + + +V V + SE+
Sbjct: 475 TAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENT 534
Query: 996 VLGEPSQDILVIDQTRLEATISPETMRTTKITEGT--TQEEFPWKEQTAEKPVPALSSTA 1053
+ + + T LE TT TEG+ T E T + + ++ A
Sbjct: 535 TVSTTGSETTTVSTTGLET--------TTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA 586
Query: 1054 WTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHK 1113
T T + + + + + ++ E + S T + + + G+ T
Sbjct: 587 STAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTV 646
Query: 1114 VKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKT 1173
TD T+ G + +++ TEGS TT +++ S +T T+ TT T
Sbjct: 647 STTDSETTMVSTTGSERTIT-------STEGSETTTVSATGSE-TTVSTEGSGTTTVSIT 698
Query: 1174 SLEDIDLG-SGLFEKPKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKK 1232
E + +G +TE E +T +T S+ TTA S + TT+A S T
Sbjct: 699 GSETTKVSTTGSETTTTSTEGSEITTASIT-GSETTTA--STEGSETTTASTEGSETTSA 755
Query: 1233 PPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTR 1292
G ETT+ E TT+ I+ ET T +S ++ T+
Sbjct: 756 -----STTGSETTTASTTSSE-------TTMASIMGSET---------TMASTIGSETTK 794
Query: 1293 PPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESK 1352
+ST +T F + I ++T +S
Sbjct: 795 --------------VSTASSKMTTVFTENSETTIASTTASETTTVS-------------- 826
Query: 1353 EDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYIN 1412
ET P +E S E E +++ TT ++
Sbjct: 827 ---TAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI---- 879
Query: 1413 GKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTE 1472
G T E +E E + ++ SE T ++T ++ +T
Sbjct: 880 GSETTTA---STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTA 936
Query: 1473 TTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQ 1532
+TE E+T T ET + G T E + TA +V+ +E
Sbjct: 937 STEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTA 996
Query: 1533 AHEHTEPVSLFPEES-SGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSA 1591
+ E +E ++ S + ++ I +E T T+ YT ++
Sbjct: 997 SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTT 1056
Query: 1592 SAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDT 1651
S SE V+ G+ + + + +E T V SGS T + A + T
Sbjct: 1057 STEGSETTTVSTTGS----ETTTASTADLETT---TVSTSGSG----TTTASTAGSETTT 1105
Query: 1652 MF---TMVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIY-PVSEQPSAKVVPTKFVS 1707
++ + T S + T ++ +S T S TT++ VSE + + S
Sbjct: 1106 VYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIG----S 1161
Query: 1708 ETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELESPNVATSSDS 1767
E TS S E T TA + +ST S E+ +T+
Sbjct: 1162 EATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGS---------ETTTASTAGSE 1212
Query: 1768 GTRKSFMSLTTPTQSEREMTDSTP--VFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLP 1825
T S T T STP +ETNT +G++TT S+ ++ T+L
Sbjct: 1213 TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAST---ASLEPTATSLT 1269
Query: 1826 RSPASVFMEQGSGEAAADPETTTVSS 1851
S + SG AA +TTVSS
Sbjct: 1270 GSETTTVSITASGATAA---STTVSS 1292
Score = 93.6 bits (231), Expect = 3e-18
Identities = 294/1484 (19%), Positives = 489/1484 (32%), Gaps = 171/1484 (11%)
Query: 407 KATVQPQAITDSLATKLPTPTGSTKKPWDMDDYSPSASGPLGKLDISEIKEEVLQSTTGV 466
KA+ A T T P+PTGS + + + G + + TT
Sbjct: 31 KASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTV--SSAGSGTTTA 88
Query: 467 SHYATDSWDGVVEDKQTQESVTQIEQIEVGPLVTSMEILKHIPSKEFPVTETP----LVT 522
S +++ + T S+T E V + S S E VT T
Sbjct: 89 SMAGSETTVSTAGSETTTVSITGTETTMVSAM-GSETTTNSTTSSETTVTSTAGSETTTV 147
Query: 523 ARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVITV 582
+ + E+ T S + TTG T+ E T + E+T + E TV
Sbjct: 148 STVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTV 207
Query: 583 SKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMD-----------DWEERQTSGRI 631
S T +T E+ +AST S GS E+ +T+
Sbjct: 208 STTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAF 267
Query: 632 TEEFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEG-ISTVIYPSLQTEMTHRRERTETL 690
TE+ STT F + + P + E +++ I P T E T
Sbjct: 268 TEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVF 327
Query: 691 IPEMRT---------DTYTDEIQEEITKSPFMG-KTEEEVFSGMKLSTSLSEPIHVTESS 740
T T E T + MG +T + +G + +T+ +E T +S
Sbjct: 328 AAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 387
Query: 741 VEMTKSFDFPTLITKLSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEAATV 800
E +++ T ++ +E T V + + T T ++T + T S E + +
Sbjct: 388 TEGSEA----TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443
Query: 801 SKWSWDEDNTTSKPLESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDS 860
+ S + TT+ E +E + + T + + + FT+ D+
Sbjct: 444 TIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDT 503
Query: 861 TQKQLEEVTDEDIAAHGK-------------------------FTIRFQPTTSTGIAEKS 895
T E ++A G T + TT++ +
Sbjct: 504 TTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEM 563
Query: 896 TLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSKPVSTVPQFAHTS-EVEGLAF 954
T +T E T G A+ GS V D ++ TS G
Sbjct: 564 TTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSET 623
Query: 955 VSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEA 1014
+ S+T TT + + +V +V + SE + + + T E
Sbjct: 624 TTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSET 683
Query: 1015 TISPETMRTTKIT---EGTTQEEFPWKEQTAEKPVPALSSTAW-TPKEAVTPLDEQEGDG 1070
T+S E TT ++ TT+ E T + +TA T E T E G
Sbjct: 684 TVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTE----G 739
Query: 1071 SAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKV 1130
S T + E GSE T G+ T T T+ +G +
Sbjct: 740 SETTTASTE---GSETTSASTT--------------GSETTTASTTSSETTMASIMGSET 782
Query: 1131 SLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEK-PK 1189
+++ T GS TT +++ S +T T+ E T T+ E + + E P
Sbjct: 783 TMA-------STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPA 835
Query: 1190 ATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMV 1249
+T E +T T S+ TTA S + TT+A SS T + G ETT+
Sbjct: 836 STAGSETTTTTSTEGSETTTA--STEGSETTTASTESSETTTATTI-----GSETTT--- 885
Query: 1250 IIGESTSHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALST 1309
ST TT ++ T + TT S ++ T T E ST
Sbjct: 886 ---ASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAST----EGSETTTAST 938
Query: 1310 PQPPASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMA 1369
+T + ++T ++ + SE+ ET V +
Sbjct: 939 EGSELTTVSTTGSETITVSAEGSETTTVTTMG-------SETTTASTAGSETTTVSTAGS 991
Query: 1370 EILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEA 1429
E S E E + ++ TT + G T + E
Sbjct: 992 ETTTA-----------SIEGSETTTVSSTGSETTTVSTT----GTETTITSTEGSETTTV 1036
Query: 1430 RRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPET 1489
E+ A ++ SE+ T ++T + +T +T LE T + T
Sbjct: 1037 TTAGSETTAV---YTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGT 1093
Query: 1490 SEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFP--EES 1547
+ + G + + + T A +V+ +E + +E ++F E+
Sbjct: 1094 TTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSET 1153
Query: 1548 SGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNP 1607
+ I E+ + A + T E ++T+ + T ++AS SE + G+
Sbjct: 1154 TTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS-TAGSETTTASTAGSETTTASTAGSE 1212
Query: 1608 WPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTD- 1666
S E+ T +S P + GS + +T F + ++ + +T
Sbjct: 1213 TTTASTSGSETNTACTT------GSETSTPSSAGS-----ETNTAFIIGSETTIASTASL 1261
Query: 1667 --TLITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKK 1724
T +L S T S AT S V T FV T I T
Sbjct: 1262 EPTATSLTGSETTTVSITASGATAA-------STTVSSTTFVLTKATDVSIQPITNTPMS 1314
Query: 1725 RKEEEGTTGTASTFEVYS-----STQRSDQLILPFELESPNVATS--------SDSGTRK 1771
GT TAS+ + + + + L + + TS S G R
Sbjct: 1315 GTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRT 1374
Query: 1772 SFMSLTTPTQSEREMTDSTPVFTETNTLENLGAQTTEHSSIHQP 1815
+ S PT S + T + T T ++ + + S QP
Sbjct: 1375 TTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPSGYLQP 1418
Score = 87.4 bits (215), Expect = 2e-16
Identities = 253/1199 (21%), Positives = 427/1199 (35%), Gaps = 185/1199 (15%)
Query: 1526 DTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPT 1585
+T V A +T S E++ + E+ + A + T ++T V+ + +
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 1586 IVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQV--VELSGSSSIPITEGSG 1643
+ ++++A SE V+ G+ ++ E+ V + V ++G+ + ++
Sbjct: 64 EITTTSTAG-SENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122
Query: 1644 EAEEDEDTMF--TMVTDLSQRNTTDTLITLDTSRIITESFFEVPATT----IYPVSEQPS 1697
E + T T+ + TT + + +T+ T A+T + V S
Sbjct: 123 ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGS 182
Query: 1698 AKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELE 1757
+ P+ SET T S T E T TA + +ST S E
Sbjct: 183 ETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGS---------E 233
Query: 1758 SPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTE---TNTLENLGAQTTEHSSIHQ 1814
+ V+T+ T + S TT +E T++ FTE T T G +TT S+
Sbjct: 234 TTKVSTAGSETTVSTAGSETTAASTEDSETNTA--FTEDSKTTTASTTGFETTAAST--- 288
Query: 1815 PGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEV--AGTLSP 1872
T + AS + + + PETT VS+ S V A E A T+
Sbjct: 289 -------TGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS 341
Query: 1873 HVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPLEE 1932
TT ST + +++M + + T S S G+E ST
Sbjct: 342 ET-TTVSTTGSETTTASIMGSETSTDSTTGSETTTASTE------GSETTTASTEGSEAT 394
Query: 1933 DFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDT---QTSPSTVPTSVHISHISDSE-- 1987
S E +TVS ++ T EGS A T T+ ST + + I+ SDSE
Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454
Query: 1988 -----GPSSTMVSTS------AFPWEEFTSSAEGSGEQLVTV--------SSSVVPVLPS 2028
G +T V+T+ A+ T++A +G + TV ++S +
Sbjct: 455 TASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514
Query: 2029 AVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNF 2088
AV +++ EG E TV+ +T + T +E T E E+ TVST
Sbjct: 515 AVSATGSEMTTVSTEG-SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMT---TVSTTG 570
Query: 2089 PQTIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTET 2148
+T + S TT+ E + S +S T + DS+T T
Sbjct: 571 AETTTDSTEGSG-------------TTAASTAGSETTTVSTADSENTTASTADSET---T 614
Query: 2149 ELKTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATEKSHFFLA 2208
TT T T S+ E + +ST D S TT+ T
Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTD-------SETTMVSTTG------- 660
Query: 2209 TALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLPT 2268
+E +T + + E+T T+ + +E S GSG T
Sbjct: 661 ---------SERTITST--EGSETT---------TVSATGSETTVSTEGSGTT------T 694
Query: 2269 ESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVT 2328
S+ +E +++ T S+ +TS++ E A G S+T GS T
Sbjct: 695 VSITGSETTKVSTT----GSETTTTSTEGSEI-----TTASITG---SETTTASTEGSET 742
Query: 2329 STTLIE-----ILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSN 2383
+T E S TG+E T + T + A I S ++ S
Sbjct: 743 TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIG-SETTKVSTASSK 801
Query: 2384 KNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPSDLYYEPSGEGSGEVDIVDSFH 2443
+ E +ETT +ST A E T + S+ P+ E
Sbjct: 802 MTTVFTENSETTIASTT----------ASETTTVSTAGSETI--PASTAGSE-------- 841
Query: 2444 TSATTQATRQESSTTFVSDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSEQNKSSPDPT 2503
+ TT +T +TT ++GS E +A +++ ++ + + S T
Sbjct: 842 -TTTTTSTEGSETTTASTEGS-----ETTTASTESSETTTATTIGSETTTASTEGSETTT 895
Query: 2504 STLSNTVSYERSTDGSFQDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDLILTITESTI 2563
++ + + ST+GS E +T+ + T E + TE +
Sbjct: 896 TSTEGSETTTASTEGS--------EITTVSTTGSETT-----TASTEGSETTTASTEGSE 942
Query: 2564 LEILPELTSDKNTIIDIDHTKPVYEDILGMQTDIDTEVPSEPHDSNDESNDDSTQVQEIY 2623
L + T + + + ++ +G +T + SE + ++ +T E
Sbjct: 943 LTTV-STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGS 1001
Query: 2624 EAAVNLSLTEETFEGSADVLASYTQATHDESMTYEDRSQLDHMGFHFTTGIPAPSTETE 2682
E S ET S + +T T + + +TTG +T TE
Sbjct: 1002 ETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV-YTTGSETTTTSTE 1059
>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 125 bits (315), Expect = 5e-28
Identities = 299/1401 (21%), Positives = 475/1401 (33%), Gaps = 88/1401 (6%)
Query: 1093 TPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPR-IGPKVSLSPGPEQKYETEGSSTTGFT 1151
+P G VS +T E T++ G + G E T GS TT
Sbjct: 49 SPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT-V 107
Query: 1152 SSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDITTAF 1211
S +T ++ + ETTT T+ + + S + + T TTA
Sbjct: 108 SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAA 167
Query: 1212 SSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKET 1271
S+ TT S IT G ETT+ + G T+ V T E A
Sbjct: 168 STTGSEMTTVFTAGSETITPSTA------GSETTT-VSTAGSETTTVSTTGSETTTASTA 220
Query: 1272 ETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRE 1331
++ S T A ST +T F D
Sbjct: 221 HSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTG 280
Query: 1332 NKTGRMSDLS---VIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEE 1388
+T S + + SE+ ET V +E+ F E +
Sbjct: 281 FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET--IRAST 338
Query: 1389 NEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSE 1448
E + TTT S+ G T E A E+ S ++ SE
Sbjct: 339 VGSETTTVSTTGSETTTASIM---GSETSTDSTTGSETTTASTEGSETTTAS---TEGSE 392
Query: 1449 SDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHE 1508
+ T ++T + +T TE E+T T ET+ + G + E
Sbjct: 393 ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452
Query: 1509 EFESGTAKKGAESVTER--DTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARAT 1566
+ T +VT +T+ + T S E++ I ++ A +
Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-ASTEGS 511
Query: 1567 EVTFGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQ 1626
E T + T ++ S SE V+ G L T + E +
Sbjct: 512 ETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG-------LETTTTSTEGSEMT 564
Query: 1627 VVELSGS-SSIPITEGSGE-AEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEV 1684
V +G+ ++ TEGSG A + T V+ NTT + +T+ T
Sbjct: 565 TVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETT 624
Query: 1685 PATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEG---TTGTASTFEVY 1741
A+T + S + T VS TD+ + STT E+ EG TT +A+ E
Sbjct: 625 TASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684
Query: 1742 SSTQRSDQLILPFE-LESPNVATSSDSGTRKSF--MSLTTPTQSEREMTDSTPVFTETNT 1798
ST+ S + E+ V+T+ T S +TT + + E T ++ +ET T
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT 744
Query: 1799 LENLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFS--LNV 1856
G++TT S+ T+ + AS+ + + + ETT VS+ S +
Sbjct: 745 ASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT 804
Query: 1857 EYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPN 1916
+ +E +A T + T + + ST T+ S S E
Sbjct: 805 VFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETT 864
Query: 1917 YGA-EIRGFSTGFPLEED---FSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPS 1972
+ E +T + + S + E +T S ++ T EGS T + +
Sbjct: 865 TASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETT 924
Query: 1973 TVPTSVHISHISDSEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQK 2032
T T + + +EG T VST+ E T SAEGS VT S +A +
Sbjct: 925 TASTEGSETTTASTEGSELTTVSTTGS--ETITVSAEGSETTTVTTMGSETTTASTAGSE 982
Query: 2033 FS--GTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQ 2090
+ TA S E + + T GT+ + E + TV+T +
Sbjct: 983 TTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE 1042
Query: 2091 TIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTETEL 2150
T A + E E SETT+ E + S + T + S T T +
Sbjct: 1043 T--TAVYTTGSETTTTSTE-GSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTA 1099
Query: 2151 --KTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATEKSHFFLA 2208
+TT + +K T + + + S + T G E T +E +
Sbjct: 1100 GSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTI 1159
Query: 2209 TALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLPT 2268
+ T S A T + + E+T G T S GS T +
Sbjct: 1160 GSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTA--------STAGSETTTASTAGS 1211
Query: 2269 ESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFE-GSGSV 2327
E+ + NT S+ + SS E N A +G S+T I S
Sbjct: 1212 ETTTASTSGSETNTACTTGSETSTPSSAGSE-----TNTAFIIG---SETTIASTASLEP 1263
Query: 2328 TSTTLIEILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSNKNSS 2387
T+T+L TG+E TV+ + + TV + T + +N S
Sbjct: 1264 TATSL------TGSETTTVS---ITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1314
Query: 2388 TAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPS--DLYYEPSGEGS---GEVDIVDSF 2442
T +++ + A G +F SA + + SG G+ G +
Sbjct: 1315 GTRTTGTRLTASSSVTMAPGM----DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAH 1370
Query: 2443 HTSATTQATRQESSTTFVSDG 2463
TT +TR+ +S+TF G
Sbjct: 1371 GVRTTTGSTREPTSSTFQETG 1391
Score = 102 bits (254), Expect = 6e-21
Identities = 284/1387 (20%), Positives = 460/1387 (33%), Gaps = 131/1387 (9%)
Query: 566 SDESTLIFDQIPEVITVSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGS-----SMD 620
S E+T+ T S T +T ++ E+ +AST S P GS S+
Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61
Query: 621 DWEERQTSGRITEEFLGKYL---STTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQ 677
E TS +E +TT + T + + + G T + ++
Sbjct: 62 GSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMG 121
Query: 678 TEMTHR----RERTETLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSL--- 730
+E T E T T T T + E T +T +G +++T
Sbjct: 122 SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG 181
Query: 731 SEPIHVTESSVEMTKSFDFPTLITKLSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAH 790
SE I + + E T + T +S +E + T + T V A
Sbjct: 182 SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241
Query: 791 GTLSVEAA----TVSKWSWDEDNTTSKPLESTEPSASSKLPPALLTTVGMNGKDKDIPSF 846
+V A T + E NT T ++++ +T G P+
Sbjct: 242 SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSE------PTM 295
Query: 847 TEDGADEFTLI----PDSTQKQLEEVTDEDIAAHGKFTIRFQPTTSTGIAEKSTLRDSTT 902
E T+ P++T+ + A G TIR S +T ++TT
Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTT 355
Query: 903 EEKVPPITSTEGQVYATMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSSTQE 962
+ TST+ + GS + ST T+ EG + S+T
Sbjct: 356 ASIMGSETSTD-----STTGSE---------TTTASTEGSETTTASTEGSEATTVSTTGS 401
Query: 963 PTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLE-ATISPETM 1021
TT V + + + + V + E +I + + E T S E
Sbjct: 402 ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS 461
Query: 1022 RTTKITEGTTQEEFPW---KEQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSED 1078
TT +T ++ + + E T ++T +T T + + +A + +
Sbjct: 462 ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGS 521
Query: 1079 ELLT----GSERVPVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSP 1134
E+ T GSE V T G +VS T + E+ T VS +
Sbjct: 522 EMTTVSTEGSENTTVSTT---GSETTTVSTTGLETTTTSTEGSEMTT--------VSTTG 570
Query: 1135 GPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATELI 1194
TEGS TT +++ S +T T E TT E + E A+
Sbjct: 571 AETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTS 630
Query: 1195 EFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGES 1254
+T T S+ TT + TT + + T I G ETT+ E+
Sbjct: 631 SETTTASTEGSETTT-------VSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSET 683
Query: 1255 T--SHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQP 1312
T + TT I ET TT++ ++ E +
Sbjct: 684 TVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETT 743
Query: 1313 PASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMAEIL 1372
AST+ + S + + + SE+ ET V +++
Sbjct: 744 TASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMT 803
Query: 1373 PEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRG 1432
F + E + + +E A + + + + G TT E +E
Sbjct: 804 TVFTENSETTIASTTASETTTVSTAGSETIPASTA-----GSETTTTT--STEGSETTTA 856
Query: 1433 QFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEH 1492
E + ++SSE+ T +T + +T +TE E T T E SE
Sbjct: 857 STEGSETTTASTESSETTT----------ATTIGSETTTASTEGSETT---TTSTEGSE- 902
Query: 1493 FSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFPEESSGEIA 1552
T E E T T TE TE L ++G
Sbjct: 903 ---------TTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSET 953
Query: 1553 IDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSAS----AYVSEEEAVTLIGNPW 1608
I ++ T T G E +++ T V ++ S A + E T+
Sbjct: 954 ITVSAE--GSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1011
Query: 1609 PDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTDTL 1668
+ST T + GS + +T E T T ++ + T T+
Sbjct: 1012 ETTTVST-----TGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTV 1066
Query: 1669 ITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEE 1728
T S T S ++ TT VS S + SET T S T E
Sbjct: 1067 STTG-SETTTASTADLETTT---VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSE 1122
Query: 1729 EGTTGTASTFEVYSSTQRSDQ-LILPFELESPNVAT-SSDSGTRKSFMSLTTPTQSE-RE 1785
T T S+ +ST S+ + E+ V+T S++ T + S T T +E E
Sbjct: 1123 ATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSE 1182
Query: 1786 MTDSTPVFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPE 1845
T ++ +ET T G++TT S+ G + + S + GS E
Sbjct: 1183 TTTASTAGSETTTASTAGSETTTAST---AGSETTTASTSGSETNTACTTGS-------E 1232
Query: 1846 TTTVSS--FSLNVEYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTS 1903
T+T SS N + I +E +A T S T T +S A + T +S
Sbjct: 1233 TSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSS 1292
Query: 1904 REIVISE 1910
V+++
Sbjct: 1293 TTFVLTK 1299
Score = 100 bits (250), Expect = 2e-20
Identities = 275/1346 (20%), Positives = 455/1346 (33%), Gaps = 156/1346 (11%)
Query: 522 TARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVIT 581
TA M T S + + TG + E T + S E+T+ E T
Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146
Query: 582 VSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGKYLS 641
VS +T + D E+ +ASTT S + GS IT G +
Sbjct: 147 VSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSE-----------TITPSTAGSETT 195
Query: 642 TTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTH-RRERTETLIPEMRTDTYT 700
T T + T ++ +E T +ET + ++T
Sbjct: 196 TVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTA 255
Query: 701 DEIQEEITKSPFM--GKTEEEVFSGMK---LSTSLSEPIHVTESSVEMTKSFDFPTLITK 755
++ T + F KT +G + ST+ SEP + E T + TK
Sbjct: 256 ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315
Query: 756 LSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPL 815
+S +EV + + T + TTV + + S+ S D +
Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 375
Query: 816 ESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDEDIAA 875
STE S + TT G + S T ++ T E ++ +
Sbjct: 376 ASTEGSET--------TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVS 427
Query: 876 HGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSK 935
T F+ TT++ E S + ++T + STEG T+ + +K
Sbjct: 428 ----TTVFETTTAS--TEGSEITIASTSDSETTTASTEGSETTTVTTAG-------SETK 474
Query: 936 PVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDE 995
T T+ GL + + TT + + +V V + SE+
Sbjct: 475 TAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENT 534
Query: 996 VLGEPSQDILVIDQTRLEATISPETMRTTKITEGT--TQEEFPWKEQTAEKPVPALSSTA 1053
+ + + T LE TT TEG+ T E T + + ++ A
Sbjct: 535 TVSTTGSETTTVSTTGLET--------TTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA 586
Query: 1054 WTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHK 1113
T T + + + + + ++ E + S T + + + G+ T
Sbjct: 587 STAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTV 646
Query: 1114 VKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKT 1173
TD T+ G + +++ TEGS TT +++ S +T T+ TT T
Sbjct: 647 STTDSETTMVSTTGSERTIT-------STEGSETTTVSATGSE-TTVSTEGSGTTTVSIT 698
Query: 1174 SLEDIDLG-SGLFEKPKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKK 1232
E + +G +TE E +T +T S+ TTA S + TT+A S T
Sbjct: 699 GSETTKVSTTGSETTTTSTEGSEITTASIT-GSETTTA--STEGSETTTASTEGSETTSA 755
Query: 1233 PPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTR 1292
G ETT+ E TT+ I+ ET T +S ++ T+
Sbjct: 756 -----STTGSETTTASTTSSE-------TTMASIMGSET---------TMASTIGSETTK 794
Query: 1293 PPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESK 1352
+ST +T F + I ++T +S
Sbjct: 795 --------------VSTASSKMTTVFTENSETTIASTTASETTTVS-------------- 826
Query: 1353 EDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYIN 1412
ET P +E S E E +++ TT ++
Sbjct: 827 ---TAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI---- 879
Query: 1413 GKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTE 1472
G T E +E E + ++ SE T ++T ++ +T
Sbjct: 880 GSETTTA---STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTA 936
Query: 1473 TTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQ 1532
+TE E+T T ET + G T E + TA +V+ +E
Sbjct: 937 STEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTA 996
Query: 1533 AHEHTEPVSLFPEES-SGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSA 1591
+ E +E ++ S + ++ I +E T T+ YT ++
Sbjct: 997 SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTT 1056
Query: 1592 SAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDT 1651
S SE V+ G+ + + + +E T V SGS T + A + T
Sbjct: 1057 STEGSETTTVSTTGS----ETTTASTADLETT---TVSTSGSG----TTTASTAGSETTT 1105
Query: 1652 MF---TMVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIY-PVSEQPSAKVVPTKFVS 1707
++ + T S + T ++ +S T S TT++ VSE + + S
Sbjct: 1106 VYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIG----S 1161
Query: 1708 ETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELESPNVATSSDS 1767
E TS S E T TA + +ST S E+ +T+
Sbjct: 1162 EATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGS---------ETTTASTAGSE 1212
Query: 1768 GTRKSFMSLTTPTQSEREMTDSTP--VFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLP 1825
T S T T STP +ETNT +G++TT S+ ++ T+L
Sbjct: 1213 TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAST---ASLEPTATSLT 1269
Query: 1826 RSPASVFMEQGSGEAAADPETTTVSS 1851
S + SG AA +TTVSS
Sbjct: 1270 GSETTTVSITASGATAA---STTVSS 1292
Score = 93.6 bits (231), Expect = 3e-18
Identities = 294/1484 (19%), Positives = 489/1484 (32%), Gaps = 171/1484 (11%)
Query: 407 KATVQPQAITDSLATKLPTPTGSTKKPWDMDDYSPSASGPLGKLDISEIKEEVLQSTTGV 466
KA+ A T T P+PTGS + + + G + + TT
Sbjct: 31 KASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTV--SSAGSGTTTA 88
Query: 467 SHYATDSWDGVVEDKQTQESVTQIEQIEVGPLVTSMEILKHIPSKEFPVTETP----LVT 522
S +++ + T S+T E V + S S E VT T
Sbjct: 89 SMAGSETTVSTAGSETTTVSITGTETTMVSAM-GSETTTNSTTSSETTVTSTAGSETTTV 147
Query: 523 ARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVITV 582
+ + E+ T S + TTG T+ E T + E+T + E TV
Sbjct: 148 STVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTV 207
Query: 583 SKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMD-----------DWEERQTSGRI 631
S T +T E+ +AST S GS E+ +T+
Sbjct: 208 STTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAF 267
Query: 632 TEEFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEG-ISTVIYPSLQTEMTHRRERTETL 690
TE+ STT F + + P + E +++ I P T E T
Sbjct: 268 TEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVF 327
Query: 691 IPEMRT---------DTYTDEIQEEITKSPFMG-KTEEEVFSGMKLSTSLSEPIHVTESS 740
T T E T + MG +T + +G + +T+ +E T +S
Sbjct: 328 AAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 387
Query: 741 VEMTKSFDFPTLITKLSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEAATV 800
E +++ T ++ +E T V + + T T ++T + T S E + +
Sbjct: 388 TEGSEA----TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443
Query: 801 SKWSWDEDNTTSKPLESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDS 860
+ S + TT+ E +E + + T + + + FT+ D+
Sbjct: 444 TIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDT 503
Query: 861 TQKQLEEVTDEDIAAHGK-------------------------FTIRFQPTTSTGIAEKS 895
T E ++A G T + TT++ +
Sbjct: 504 TTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEM 563
Query: 896 TLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSKPVSTVPQFAHTS-EVEGLAF 954
T +T E T G A+ GS V D ++ TS G
Sbjct: 564 TTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSET 623
Query: 955 VSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEA 1014
+ S+T TT + + +V +V + SE + + + T E
Sbjct: 624 TTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSET 683
Query: 1015 TISPETMRTTKIT---EGTTQEEFPWKEQTAEKPVPALSSTAW-TPKEAVTPLDEQEGDG 1070
T+S E TT ++ TT+ E T + +TA T E T E G
Sbjct: 684 TVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTE----G 739
Query: 1071 SAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKV 1130
S T + E GSE T G+ T T T+ +G +
Sbjct: 740 SETTTASTE---GSETTSASTT--------------GSETTTASTTSSETTMASIMGSET 782
Query: 1131 SLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEK-PK 1189
+++ T GS TT +++ S +T T+ E T T+ E + + E P
Sbjct: 783 TMA-------STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPA 835
Query: 1190 ATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMV 1249
+T E +T T S+ TTA S + TT+A SS T + G ETT+
Sbjct: 836 STAGSETTTTTSTEGSETTTA--STEGSETTTASTESSETTTATTI-----GSETTT--- 885
Query: 1250 IIGESTSHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALST 1309
ST TT ++ T + TT S ++ T T E ST
Sbjct: 886 ---ASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAST----EGSETTTAST 938
Query: 1310 PQPPASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMA 1369
+T + ++T ++ + SE+ ET V +
Sbjct: 939 EGSELTTVSTTGSETITVSAEGSETTTVTTMG-------SETTTASTAGSETTTVSTAGS 991
Query: 1370 EILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEA 1429
E S E E + ++ TT + G T + E
Sbjct: 992 ETTTA-----------SIEGSETTTVSSTGSETTTVSTT----GTETTITSTEGSETTTV 1036
Query: 1430 RRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPET 1489
E+ A ++ SE+ T ++T + +T +T LE T + T
Sbjct: 1037 TTAGSETTAV---YTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGT 1093
Query: 1490 SEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFP--EES 1547
+ + G + + + T A +V+ +E + +E ++F E+
Sbjct: 1094 TTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSET 1153
Query: 1548 SGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNP 1607
+ I E+ + A + T E ++T+ + T ++AS SE + G+
Sbjct: 1154 TTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS-TAGSETTTASTAGSETTTASTAGSE 1212
Query: 1608 WPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTD- 1666
S E+ T +S P + GS + +T F + ++ + +T
Sbjct: 1213 TTTASTSGSETNTACTT------GSETSTPSSAGS-----ETNTAFIIGSETTIASTASL 1261
Query: 1667 --TLITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKK 1724
T +L S T S AT S V T FV T I T
Sbjct: 1262 EPTATSLTGSETTTVSITASGATAA-------STTVSSTTFVLTKATDVSIQPITNTPMS 1314
Query: 1725 RKEEEGTTGTASTFEVYS-----STQRSDQLILPFELESPNVATS--------SDSGTRK 1771
GT TAS+ + + + + L + + TS S G R
Sbjct: 1315 GTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRT 1374
Query: 1772 SFMSLTTPTQSEREMTDSTPVFTETNTLENLGAQTTEHSSIHQP 1815
+ S PT S + T + T T ++ + + S QP
Sbjct: 1375 TTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPSGYLQP 1418
Score = 87.4 bits (215), Expect = 2e-16
Identities = 253/1199 (21%), Positives = 427/1199 (35%), Gaps = 185/1199 (15%)
Query: 1526 DTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPT 1585
+T V A +T S E++ + E+ + A + T ++T V+ + +
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 1586 IVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQV--VELSGSSSIPITEGSG 1643
+ ++++A SE V+ G+ ++ E+ V + V ++G+ + ++
Sbjct: 64 EITTTSTAG-SENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122
Query: 1644 EAEEDEDTMF--TMVTDLSQRNTTDTLITLDTSRIITESFFEVPATT----IYPVSEQPS 1697
E + T T+ + TT + + +T+ T A+T + V S
Sbjct: 123 ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGS 182
Query: 1698 AKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELE 1757
+ P+ SET T S T E T TA + +ST S E
Sbjct: 183 ETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGS---------E 233
Query: 1758 SPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTE---TNTLENLGAQTTEHSSIHQ 1814
+ V+T+ T + S TT +E T++ FTE T T G +TT S+
Sbjct: 234 TTKVSTAGSETTVSTAGSETTAASTEDSETNTA--FTEDSKTTTASTTGFETTAAST--- 288
Query: 1815 PGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEV--AGTLSP 1872
T + AS + + + PETT VS+ S V A E A T+
Sbjct: 289 -------TGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS 341
Query: 1873 HVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPLEE 1932
TT ST + +++M + + T S S G+E ST
Sbjct: 342 ET-TTVSTTGSETTTASIMGSETSTDSTTGSETTTASTE------GSETTTASTEGSEAT 394
Query: 1933 DFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDT---QTSPSTVPTSVHISHISDSE-- 1987
S E +TVS ++ T EGS A T T+ ST + + I+ SDSE
Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454
Query: 1988 -----GPSSTMVSTS------AFPWEEFTSSAEGSGEQLVTV--------SSSVVPVLPS 2028
G +T V+T+ A+ T++A +G + TV ++S +
Sbjct: 455 TASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514
Query: 2029 AVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNF 2088
AV +++ EG E TV+ +T + T +E T E E+ TVST
Sbjct: 515 AVSATGSEMTTVSTEG-SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMT---TVSTTG 570
Query: 2089 PQTIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTET 2148
+T + S TT+ E + S +S T + DS+T T
Sbjct: 571 AETTTDSTEGSG-------------TTAASTAGSETTTVSTADSENTTASTADSET---T 614
Query: 2149 ELKTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATEKSHFFLA 2208
TT T T S+ E + +ST D S TT+ T
Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTD-------SETTMVSTTG------- 660
Query: 2209 TALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLPT 2268
+E +T + + E+T T+ + +E S GSG T
Sbjct: 661 ---------SERTITST--EGSETT---------TVSATGSETTVSTEGSGTT------T 694
Query: 2269 ESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVT 2328
S+ +E +++ T S+ +TS++ E A G S+T GS T
Sbjct: 695 VSITGSETTKVSTT----GSETTTTSTEGSEI-----TTASITG---SETTTASTEGSET 742
Query: 2329 STTLIE-----ILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSN 2383
+T E S TG+E T + T + A I S ++ S
Sbjct: 743 TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIG-SETTKVSTASSK 801
Query: 2384 KNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPSDLYYEPSGEGSGEVDIVDSFH 2443
+ E +ETT +ST A E T + S+ P+ E
Sbjct: 802 MTTVFTENSETTIASTT----------ASETTTVSTAGSETI--PASTAGSE-------- 841
Query: 2444 TSATTQATRQESSTTFVSDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSEQNKSSPDPT 2503
+ TT +T +TT ++GS E +A +++ ++ + + S T
Sbjct: 842 -TTTTTSTEGSETTTASTEGS-----ETTTASTESSETTTATTIGSETTTASTEGSETTT 895
Query: 2504 STLSNTVSYERSTDGSFQDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDLILTITESTI 2563
++ + + ST+GS E +T+ + T E + TE +
Sbjct: 896 TSTEGSETTTASTEGS--------EITTVSTTGSETT-----TASTEGSETTTASTEGSE 942
Query: 2564 LEILPELTSDKNTIIDIDHTKPVYEDILGMQTDIDTEVPSEPHDSNDESNDDSTQVQEIY 2623
L + T + + + ++ +G +T + SE + ++ +T E
Sbjct: 943 LTTV-STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGS 1001
Query: 2624 EAAVNLSLTEETFEGSADVLASYTQATHDESMTYEDRSQLDHMGFHFTTGIPAPSTETE 2682
E S ET S + +T T + + +TTG +T TE
Sbjct: 1002 ETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV-YTTGSETTTTSTE 1059
>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 125 bits (315), Expect = 5e-28
Identities = 299/1401 (21%), Positives = 475/1401 (33%), Gaps = 88/1401 (6%)
Query: 1093 TPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPR-IGPKVSLSPGPEQKYETEGSSTTGFT 1151
+P G VS +T E T++ G + G E T GS TT
Sbjct: 49 SPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT-V 107
Query: 1152 SSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDITTAF 1211
S +T ++ + ETTT T+ + + S + + T TTA
Sbjct: 108 SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAA 167
Query: 1212 SSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKET 1271
S+ TT S IT G ETT+ + G T+ V T E A
Sbjct: 168 STTGSEMTTVFTAGSETITPSTA------GSETTT-VSTAGSETTTVSTTGSETTTASTA 220
Query: 1272 ETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRE 1331
++ S T A ST +T F D
Sbjct: 221 HSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTG 280
Query: 1332 NKTGRMSDLS---VIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEE 1388
+T S + + SE+ ET V +E+ F E +
Sbjct: 281 FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET--IRAST 338
Query: 1389 NEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSE 1448
E + TTT S+ G T E A E+ S ++ SE
Sbjct: 339 VGSETTTVSTTGSETTTASIM---GSETSTDSTTGSETTTASTEGSETTTAS---TEGSE 392
Query: 1449 SDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHE 1508
+ T ++T + +T TE E+T T ET+ + G + E
Sbjct: 393 ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452
Query: 1509 EFESGTAKKGAESVTER--DTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARAT 1566
+ T +VT +T+ + T S E++ I ++ A +
Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-ASTEGS 511
Query: 1567 EVTFGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQ 1626
E T + T ++ S SE V+ G L T + E +
Sbjct: 512 ETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG-------LETTTTSTEGSEMT 564
Query: 1627 VVELSGS-SSIPITEGSGE-AEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEV 1684
V +G+ ++ TEGSG A + T V+ NTT + +T+ T
Sbjct: 565 TVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETT 624
Query: 1685 PATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEG---TTGTASTFEVY 1741
A+T + S + T VS TD+ + STT E+ EG TT +A+ E
Sbjct: 625 TASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684
Query: 1742 SSTQRSDQLILPFE-LESPNVATSSDSGTRKSF--MSLTTPTQSEREMTDSTPVFTETNT 1798
ST+ S + E+ V+T+ T S +TT + + E T ++ +ET T
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT 744
Query: 1799 LENLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFS--LNV 1856
G++TT S+ T+ + AS+ + + + ETT VS+ S +
Sbjct: 745 ASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT 804
Query: 1857 EYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPN 1916
+ +E +A T + T + + ST T+ S S E
Sbjct: 805 VFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETT 864
Query: 1917 YGA-EIRGFSTGFPLEED---FSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPS 1972
+ E +T + + S + E +T S ++ T EGS T + +
Sbjct: 865 TASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETT 924
Query: 1973 TVPTSVHISHISDSEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQK 2032
T T + + +EG T VST+ E T SAEGS VT S +A +
Sbjct: 925 TASTEGSETTTASTEGSELTTVSTTGS--ETITVSAEGSETTTVTTMGSETTTASTAGSE 982
Query: 2033 FS--GTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQ 2090
+ TA S E + + T GT+ + E + TV+T +
Sbjct: 983 TTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSE 1042
Query: 2091 TIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTETEL 2150
T A + E E SETT+ E + S + T + S T T +
Sbjct: 1043 T--TAVYTTGSETTTTSTE-GSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTA 1099
Query: 2151 --KTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATEKSHFFLA 2208
+TT + +K T + + + S + T G E T +E +
Sbjct: 1100 GSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTI 1159
Query: 2209 TALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLPT 2268
+ T S A T + + E+T G T S GS T +
Sbjct: 1160 GSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTA--------STAGSETTTASTAGS 1211
Query: 2269 ESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFE-GSGSV 2327
E+ + NT S+ + SS E N A +G S+T I S
Sbjct: 1212 ETTTASTSGSETNTACTTGSETSTPSSAGSE-----TNTAFIIG---SETTIASTASLEP 1263
Query: 2328 TSTTLIEILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSNKNSS 2387
T+T+L TG+E TV+ + + TV + T + +N S
Sbjct: 1264 TATSL------TGSETTTVS---ITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1314
Query: 2388 TAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPS--DLYYEPSGEGS---GEVDIVDSF 2442
T +++ + A G +F SA + + SG G+ G +
Sbjct: 1315 GTRTTGTRLTASSSVTMAPGM----DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAH 1370
Query: 2443 HTSATTQATRQESSTTFVSDG 2463
TT +TR+ +S+TF G
Sbjct: 1371 GVRTTTGSTREPTSSTFQETG 1391
Score = 102 bits (254), Expect = 6e-21
Identities = 284/1387 (20%), Positives = 460/1387 (33%), Gaps = 131/1387 (9%)
Query: 566 SDESTLIFDQIPEVITVSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGS-----SMD 620
S E+T+ T S T +T ++ E+ +AST S P GS S+
Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61
Query: 621 DWEERQTSGRITEEFLGKYL---STTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQ 677
E TS +E +TT + T + + + G T + ++
Sbjct: 62 GSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMG 121
Query: 678 TEMTHR----RERTETLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSL--- 730
+E T E T T T T + E T +T +G +++T
Sbjct: 122 SETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAG 181
Query: 731 SEPIHVTESSVEMTKSFDFPTLITKLSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAH 790
SE I + + E T + T +S +E + T + T V A
Sbjct: 182 SETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAG 241
Query: 791 GTLSVEAA----TVSKWSWDEDNTTSKPLESTEPSASSKLPPALLTTVGMNGKDKDIPSF 846
+V A T + E NT T ++++ +T G P+
Sbjct: 242 SETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSE------PTM 295
Query: 847 TEDGADEFTLI----PDSTQKQLEEVTDEDIAAHGKFTIRFQPTTSTGIAEKSTLRDSTT 902
E T+ P++T+ + A G TIR S +T ++TT
Sbjct: 296 ASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTT 355
Query: 903 EEKVPPITSTEGQVYATMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSSTQE 962
+ TST+ + GS + ST T+ EG + S+T
Sbjct: 356 ASIMGSETSTD-----STTGSE---------TTTASTEGSETTTASTEGSEATTVSTTGS 401
Query: 963 PTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLE-ATISPETM 1021
TT V + + + + V + E +I + + E T S E
Sbjct: 402 ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGS 461
Query: 1022 RTTKITEGTTQEEFPW---KEQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSED 1078
TT +T ++ + + E T ++T +T T + + +A + +
Sbjct: 462 ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGS 521
Query: 1079 ELLT----GSERVPVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSP 1134
E+ T GSE V T G +VS T + E+ T VS +
Sbjct: 522 EMTTVSTEGSENTTVSTT---GSETTTVSTTGLETTTTSTEGSEMTT--------VSTTG 570
Query: 1135 GPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATELI 1194
TEGS TT +++ S +T T E TT E + E A+
Sbjct: 571 AETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTS 630
Query: 1195 EFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGES 1254
+T T S+ TT + TT + + T I G ETT+ E+
Sbjct: 631 SETTTASTEGSETTT-------VSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSET 683
Query: 1255 T--SHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQP 1312
T + TT I ET TT++ ++ E +
Sbjct: 684 TVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETT 743
Query: 1313 PASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMAEIL 1372
AST+ + S + + + SE+ ET V +++
Sbjct: 744 TASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMT 803
Query: 1373 PEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRG 1432
F + E + + +E A + + + + G TT E +E
Sbjct: 804 TVFTENSETTIASTTASETTTVSTAGSETIPASTA-----GSETTTTT--STEGSETTTA 856
Query: 1433 QFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEH 1492
E + ++SSE+ T +T + +T +TE E T T E SE
Sbjct: 857 STEGSETTTASTESSETTT----------ATTIGSETTTASTEGSETT---TTSTEGSE- 902
Query: 1493 FSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFPEESSGEIA 1552
T E E T T TE TE L ++G
Sbjct: 903 ---------TTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSET 953
Query: 1553 IDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSAS----AYVSEEEAVTLIGNPW 1608
I ++ T T G E +++ T V ++ S A + E T+
Sbjct: 954 ITVSAE--GSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGS 1011
Query: 1609 PDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTDTL 1668
+ST T + GS + +T E T T ++ + T T+
Sbjct: 1012 ETTTVST-----TGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTV 1066
Query: 1669 ITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEE 1728
T S T S ++ TT VS S + SET T S T E
Sbjct: 1067 STTG-SETTTASTADLETTT---VSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSE 1122
Query: 1729 EGTTGTASTFEVYSSTQRSDQ-LILPFELESPNVAT-SSDSGTRKSFMSLTTPTQSE-RE 1785
T T S+ +ST S+ + E+ V+T S++ T + S T T +E E
Sbjct: 1123 ATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSE 1182
Query: 1786 MTDSTPVFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPE 1845
T ++ +ET T G++TT S+ G + + S + GS E
Sbjct: 1183 TTTASTAGSETTTASTAGSETTTAST---AGSETTTASTSGSETNTACTTGS-------E 1232
Query: 1846 TTTVSS--FSLNVEYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTS 1903
T+T SS N + I +E +A T S T T +S A + T +S
Sbjct: 1233 TSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSS 1292
Query: 1904 REIVISE 1910
V+++
Sbjct: 1293 TTFVLTK 1299
Score = 100 bits (250), Expect = 2e-20
Identities = 275/1346 (20%), Positives = 455/1346 (33%), Gaps = 156/1346 (11%)
Query: 522 TARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVIT 581
TA M T S + + TG + E T + S E+T+ E T
Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146
Query: 582 VSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGKYLS 641
VS +T + D E+ +ASTT S + GS IT G +
Sbjct: 147 VSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSE-----------TITPSTAGSETT 195
Query: 642 TTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTH-RRERTETLIPEMRTDTYT 700
T T + T ++ +E T +ET + ++T
Sbjct: 196 TVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTA 255
Query: 701 DEIQEEITKSPFM--GKTEEEVFSGMK---LSTSLSEPIHVTESSVEMTKSFDFPTLITK 755
++ T + F KT +G + ST+ SEP + E T + TK
Sbjct: 256 ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315
Query: 756 LSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPL 815
+S +EV + + T + TTV + + S+ S D +
Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 375
Query: 816 ESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDEDIAA 875
STE S + TT G + S T ++ T E ++ +
Sbjct: 376 ASTEGSET--------TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVS 427
Query: 876 HGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSK 935
T F+ TT++ E S + ++T + STEG T+ + +K
Sbjct: 428 ----TTVFETTTAS--TEGSEITIASTSDSETTTASTEGSETTTVTTAG-------SETK 474
Query: 936 PVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDE 995
T T+ GL + + TT + + +V V + SE+
Sbjct: 475 TAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENT 534
Query: 996 VLGEPSQDILVIDQTRLEATISPETMRTTKITEGT--TQEEFPWKEQTAEKPVPALSSTA 1053
+ + + T LE TT TEG+ T E T + + ++ A
Sbjct: 535 TVSTTGSETTTVSTTGLET--------TTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA 586
Query: 1054 WTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHK 1113
T T + + + + + ++ E + S T + + + G+ T
Sbjct: 587 STAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTV 646
Query: 1114 VKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKT 1173
TD T+ G + +++ TEGS TT +++ S +T T+ TT T
Sbjct: 647 STTDSETTMVSTTGSERTIT-------STEGSETTTVSATGSE-TTVSTEGSGTTTVSIT 698
Query: 1174 SLEDIDLG-SGLFEKPKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKK 1232
E + +G +TE E +T +T S+ TTA S + TT+A S T
Sbjct: 699 GSETTKVSTTGSETTTTSTEGSEITTASIT-GSETTTA--STEGSETTTASTEGSETTSA 755
Query: 1233 PPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTR 1292
G ETT+ E TT+ I+ ET T +S ++ T+
Sbjct: 756 -----STTGSETTTASTTSSE-------TTMASIMGSET---------TMASTIGSETTK 794
Query: 1293 PPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESK 1352
+ST +T F + I ++T +S
Sbjct: 795 --------------VSTASSKMTTVFTENSETTIASTTASETTTVS-------------- 826
Query: 1353 EDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYIN 1412
ET P +E S E E +++ TT ++
Sbjct: 827 ---TAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI---- 879
Query: 1413 GKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTE 1472
G T E +E E + ++ SE T ++T ++ +T
Sbjct: 880 GSETTTA---STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTA 936
Query: 1473 TTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQ 1532
+TE E+T T ET + G T E + TA +V+ +E
Sbjct: 937 STEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTA 996
Query: 1533 AHEHTEPVSLFPEES-SGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSA 1591
+ E +E ++ S + ++ I +E T T+ YT ++
Sbjct: 997 SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTT 1056
Query: 1592 SAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDT 1651
S SE V+ G+ + + + +E T V SGS T + A + T
Sbjct: 1057 STEGSETTTVSTTGS----ETTTASTADLETT---TVSTSGSG----TTTASTAGSETTT 1105
Query: 1652 MF---TMVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIY-PVSEQPSAKVVPTKFVS 1707
++ + T S + T ++ +S T S TT++ VSE + + S
Sbjct: 1106 VYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIG----S 1161
Query: 1708 ETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELESPNVATSSDS 1767
E TS S E T TA + +ST S E+ +T+
Sbjct: 1162 EATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGS---------ETTTASTAGSE 1212
Query: 1768 GTRKSFMSLTTPTQSEREMTDSTP--VFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLP 1825
T S T T STP +ETNT +G++TT S+ ++ T+L
Sbjct: 1213 TTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAST---ASLEPTATSLT 1269
Query: 1826 RSPASVFMEQGSGEAAADPETTTVSS 1851
S + SG AA +TTVSS
Sbjct: 1270 GSETTTVSITASGATAA---STTVSS 1292
Score = 93.6 bits (231), Expect = 3e-18
Identities = 294/1484 (19%), Positives = 489/1484 (32%), Gaps = 171/1484 (11%)
Query: 407 KATVQPQAITDSLATKLPTPTGSTKKPWDMDDYSPSASGPLGKLDISEIKEEVLQSTTGV 466
KA+ A T T P+PTGS + + + G + + TT
Sbjct: 31 KASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTV--SSAGSGTTTA 88
Query: 467 SHYATDSWDGVVEDKQTQESVTQIEQIEVGPLVTSMEILKHIPSKEFPVTETP----LVT 522
S +++ + T S+T E V + S S E VT T
Sbjct: 89 SMAGSETTVSTAGSETTTVSITGTETTMVSAM-GSETTTNSTTSSETTVTSTAGSETTTV 147
Query: 523 ARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVITV 582
+ + E+ T S + TTG T+ E T + E+T + E TV
Sbjct: 148 STVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTV 207
Query: 583 SKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMD-----------DWEERQTSGRI 631
S T +T E+ +AST S GS E+ +T+
Sbjct: 208 STTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAF 267
Query: 632 TEEFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEG-ISTVIYPSLQTEMTHRRERTETL 690
TE+ STT F + + P + E +++ I P T E T
Sbjct: 268 TEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVF 327
Query: 691 IPEMRT---------DTYTDEIQEEITKSPFMG-KTEEEVFSGMKLSTSLSEPIHVTESS 740
T T E T + MG +T + +G + +T+ +E T +S
Sbjct: 328 AAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTAS 387
Query: 741 VEMTKSFDFPTLITKLSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEAATV 800
E +++ T ++ +E T V + + T T ++T + T S E + +
Sbjct: 388 TEGSEA----TTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEI 443
Query: 801 SKWSWDEDNTTSKPLESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDS 860
+ S + TT+ E +E + + T + + + FT+ D+
Sbjct: 444 TIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDT 503
Query: 861 TQKQLEEVTDEDIAAHGK-------------------------FTIRFQPTTSTGIAEKS 895
T E ++A G T + TT++ +
Sbjct: 504 TTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEM 563
Query: 896 TLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSKPVSTVPQFAHTS-EVEGLAF 954
T +T E T G A+ GS V D ++ TS G
Sbjct: 564 TTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSET 623
Query: 955 VSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEA 1014
+ S+T TT + + +V +V + SE + + + T E
Sbjct: 624 TTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSET 683
Query: 1015 TISPETMRTTKIT---EGTTQEEFPWKEQTAEKPVPALSSTAW-TPKEAVTPLDEQEGDG 1070
T+S E TT ++ TT+ E T + +TA T E T E G
Sbjct: 684 TVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTE----G 739
Query: 1071 SAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKV 1130
S T + E GSE T G+ T T T+ +G +
Sbjct: 740 SETTTASTE---GSETTSASTT--------------GSETTTASTTSSETTMASIMGSET 782
Query: 1131 SLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEK-PK 1189
+++ T GS TT +++ S +T T+ E T T+ E + + E P
Sbjct: 783 TMA-------STIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPA 835
Query: 1190 ATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMV 1249
+T E +T T S+ TTA S + TT+A SS T + G ETT+
Sbjct: 836 STAGSETTTTTSTEGSETTTA--STEGSETTTASTESSETTTATTI-----GSETTT--- 885
Query: 1250 IIGESTSHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALST 1309
ST TT ++ T + TT S ++ T T E ST
Sbjct: 886 ---ASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAST----EGSETTTAST 938
Query: 1310 PQPPASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMA 1369
+T + ++T ++ + SE+ ET V +
Sbjct: 939 EGSELTTVSTTGSETITVSAEGSETTTVTTMG-------SETTTASTAGSETTTVSTAGS 991
Query: 1370 EILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEA 1429
E S E E + ++ TT + G T + E
Sbjct: 992 ETTTA-----------SIEGSETTTVSSTGSETTTVSTT----GTETTITSTEGSETTTV 1036
Query: 1430 RRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPET 1489
E+ A ++ SE+ T ++T + +T +T LE T + T
Sbjct: 1037 TTAGSETTAV---YTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGT 1093
Query: 1490 SEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFP--EES 1547
+ + G + + + T A +V+ +E + +E ++F E+
Sbjct: 1094 TTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSET 1153
Query: 1548 SGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNP 1607
+ I E+ + A + T E ++T+ + T ++AS SE + G+
Sbjct: 1154 TTVSTIGSEATTSSAAGSEATTTSTEGSETTTAS-TAGSETTTASTAGSETTTASTAGSE 1212
Query: 1608 WPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTD- 1666
S E+ T +S P + GS + +T F + ++ + +T
Sbjct: 1213 TTTASTSGSETNTACTT------GSETSTPSSAGS-----ETNTAFIIGSETTIASTASL 1261
Query: 1667 --TLITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKK 1724
T +L S T S AT S V T FV T I T
Sbjct: 1262 EPTATSLTGSETTTVSITASGATAA-------STTVSSTTFVLTKATDVSIQPITNTPMS 1314
Query: 1725 RKEEEGTTGTASTFEVYS-----STQRSDQLILPFELESPNVATS--------SDSGTRK 1771
GT TAS+ + + + + L + + TS S G R
Sbjct: 1315 GTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRT 1374
Query: 1772 SFMSLTTPTQSEREMTDSTPVFTETNTLENLGAQTTEHSSIHQP 1815
+ S PT S + T + T T ++ + + S QP
Sbjct: 1375 TTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPSGYLQP 1418
Score = 87.4 bits (215), Expect = 2e-16
Identities = 253/1199 (21%), Positives = 427/1199 (35%), Gaps = 185/1199 (15%)
Query: 1526 DTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPT 1585
+T V A +T S E++ + E+ + A + T ++T V+ + +
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 1586 IVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQV--VELSGSSSIPITEGSG 1643
+ ++++A SE V+ G+ ++ E+ V + V ++G+ + ++
Sbjct: 64 EITTTSTAG-SENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122
Query: 1644 EAEEDEDTMF--TMVTDLSQRNTTDTLITLDTSRIITESFFEVPATT----IYPVSEQPS 1697
E + T T+ + TT + + +T+ T A+T + V S
Sbjct: 123 ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGS 182
Query: 1698 AKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELE 1757
+ P+ SET T S T E T TA + +ST S E
Sbjct: 183 ETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGS---------E 233
Query: 1758 SPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTE---TNTLENLGAQTTEHSSIHQ 1814
+ V+T+ T + S TT +E T++ FTE T T G +TT S+
Sbjct: 234 TTKVSTAGSETTVSTAGSETTAASTEDSETNTA--FTEDSKTTTASTTGFETTAAST--- 288
Query: 1815 PGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEV--AGTLSP 1872
T + AS + + + PETT VS+ S V A E A T+
Sbjct: 289 -------TGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS 341
Query: 1873 HVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPLEE 1932
TT ST + +++M + + T S S G+E ST
Sbjct: 342 ET-TTVSTTGSETTTASIMGSETSTDSTTGSETTTASTE------GSETTTASTEGSEAT 394
Query: 1933 DFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDT---QTSPSTVPTSVHISHISDSE-- 1987
S E +TVS ++ T EGS A T T+ ST + + I+ SDSE
Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454
Query: 1988 -----GPSSTMVSTS------AFPWEEFTSSAEGSGEQLVTV--------SSSVVPVLPS 2028
G +T V+T+ A+ T++A +G + TV ++S +
Sbjct: 455 TASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514
Query: 2029 AVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNF 2088
AV +++ EG E TV+ +T + T +E T E E+ TVST
Sbjct: 515 AVSATGSEMTTVSTEG-SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMT---TVSTTG 570
Query: 2089 PQTIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTET 2148
+T + S TT+ E + S +S T + DS+T T
Sbjct: 571 AETTTDSTEGSG-------------TTAASTAGSETTTVSTADSENTTASTADSET---T 614
Query: 2149 ELKTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATEKSHFFLA 2208
TT T T S+ E + +ST D S TT+ T
Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTD-------SETTMVSTTG------- 660
Query: 2209 TALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLPT 2268
+E +T + + E+T T+ + +E S GSG T
Sbjct: 661 ---------SERTITST--EGSETT---------TVSATGSETTVSTEGSGTT------T 694
Query: 2269 ESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVT 2328
S+ +E +++ T S+ +TS++ E A G S+T GS T
Sbjct: 695 VSITGSETTKVSTT----GSETTTTSTEGSEI-----TTASITG---SETTTASTEGSET 742
Query: 2329 STTLIE-----ILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSN 2383
+T E S TG+E T + T + A I S ++ S
Sbjct: 743 TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIG-SETTKVSTASSK 801
Query: 2384 KNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPSDLYYEPSGEGSGEVDIVDSFH 2443
+ E +ETT +ST A E T + S+ P+ E
Sbjct: 802 MTTVFTENSETTIASTT----------ASETTTVSTAGSETI--PASTAGSE-------- 841
Query: 2444 TSATTQATRQESSTTFVSDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSEQNKSSPDPT 2503
+ TT +T +TT ++GS E +A +++ ++ + + S T
Sbjct: 842 -TTTTTSTEGSETTTASTEGS-----ETTTASTESSETTTATTIGSETTTASTEGSETTT 895
Query: 2504 STLSNTVSYERSTDGSFQDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDLILTITESTI 2563
++ + + ST+GS E +T+ + T E + TE +
Sbjct: 896 TSTEGSETTTASTEGS--------EITTVSTTGSETT-----TASTEGSETTTASTEGSE 942
Query: 2564 LEILPELTSDKNTIIDIDHTKPVYEDILGMQTDIDTEVPSEPHDSNDESNDDSTQVQEIY 2623
L + T + + + ++ +G +T + SE + ++ +T E
Sbjct: 943 LTTV-STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGS 1001
Query: 2624 EAAVNLSLTEETFEGSADVLASYTQATHDESMTYEDRSQLDHMGFHFTTGIPAPSTETE 2682
E S ET S + +T T + + +TTG +T TE
Sbjct: 1002 ETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV-YTTGSETTTTSTE 1059
>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1542
Score = 124 bits (311), Expect = 2e-27
Identities = 303/1401 (21%), Positives = 479/1401 (34%), Gaps = 98/1401 (6%)
Query: 1093 TPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPR-IGPKVSLSPGPEQKYETEGSSTTGFT 1151
+P G VS +T E T++ G + G E T GS TT
Sbjct: 70 SPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGSETTT-V 128
Query: 1152 SSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDITTAF 1211
S +T ++ + ETTT T+ + + S + + T TTA
Sbjct: 129 SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAA 188
Query: 1212 SSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKET 1271
S+ TT S IT G ETT+ + G T+ V T E A
Sbjct: 189 STTGSEMTTVFTAGSETITPSTA------GSETTT-VSTAGSETTTVSTTGSETTTASTA 241
Query: 1272 ETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRE 1331
++ S T A ST +T F D
Sbjct: 242 HSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTG 301
Query: 1332 NKTGRMSDLS---VIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEE 1388
+T S + + SE+ ET V +E+ F E +
Sbjct: 302 FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET--IRAST 359
Query: 1389 NEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSE 1448
E + TTT S+ G T E A E+ S ++ SE
Sbjct: 360 VGSETTTVSTTGSETTTASIM---GSETSTDSTTGSETTTASTEGSETTTAS---TEGSE 413
Query: 1449 SDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHE 1508
+ T ++T + +T TE E+T T ET+ + G + E
Sbjct: 414 ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 473
Query: 1509 EFESGTAKKGAESVTER--DTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARAT 1566
+ T +VT +T+ + T S E++ I ++ A +
Sbjct: 474 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-ASTEGS 532
Query: 1567 EVTFGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQ 1626
E T + T ++ S SE V+ G L T + E +
Sbjct: 533 ETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG-------LETTTTSTEGSEMT 585
Query: 1627 VVELSGS-SSIPITEGSGE-AEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEV 1684
V +G+ ++ TEGSG A + T V+ NTT + +T+ T
Sbjct: 586 TVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETT 645
Query: 1685 PATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEG---TTGTASTFEVY 1741
A+T + S + T VS TD+ + STT E+ EG TT +A+ E
Sbjct: 646 TASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 705
Query: 1742 SSTQRSDQLILPFE-LESPNVATSSDSGTRKSF--MSLTTPTQSEREMTDSTPVFTETNT 1798
ST+ S + E+ V+T+ T S +TT + + E T ++ +ET T
Sbjct: 706 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT 765
Query: 1799 LENLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFS--LNV 1856
G++TT S+ T+ + AS+ + + + ETT VS+ S +
Sbjct: 766 ASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT 825
Query: 1857 EYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPN 1916
+ +E +A T + T + + ST T+ S S E
Sbjct: 826 VFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETT 885
Query: 1917 YGA-EIRGFSTGFPLEED---FSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPS 1972
+ E +T + + S + E +T S ++ T EGS T + +
Sbjct: 886 TASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETT 945
Query: 1973 TVPTSVHISHISDSEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQK 2032
T T + + +EG T VST+ E T SAEGS VT S
Sbjct: 946 TASTEGSETTTASTEGSELTTVSTTGS--ETITVSAEGSETTTVTTMGSETTT------- 996
Query: 2033 FSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQTI 2092
+ TA S E TV+ +T TA +EG++ + TVST +T
Sbjct: 997 -ASTAGS-------ETTTVSTAGSETT---TASIEGSETTTVSSTGSETTTVSTTGTETT 1045
Query: 2093 EPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTET--EL 2150
+ S E V SETT+ E + S + S T + S+T T + +L
Sbjct: 1046 ITSTEGS--ETTTV-TTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL 1102
Query: 2151 KTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATE-KSHFFLAT 2209
+TT S + T + + + T G E+ T ++E + +
Sbjct: 1103 ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGS 1162
Query: 2210 ALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTE-LLFSGLGSGEEVLPTLPT 2268
+ T T S I E +T T +E S GS T +
Sbjct: 1163 EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGS 1222
Query: 2269 ESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFE-GSGSV 2327
E+ + NT S+ + SS E N A +G S+T I S
Sbjct: 1223 ETTTASTSGSETNTACTTGSETSTPSSAGSE-----TNTAFIIG---SETTIASTASLEP 1274
Query: 2328 TSTTLIEILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSNKNSS 2387
T+T+L TG+E TV+ + + TV + T + +N S
Sbjct: 1275 TATSL------TGSETTTVS---ITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1325
Query: 2388 TAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPS--DLYYEPSGEGS---GEVDIVDSF 2442
T +++ + A G +F SA + + SG G+ G +
Sbjct: 1326 GTRTTGTRLTASSSVTMAPGM----DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAH 1381
Query: 2443 HTSATTQATRQESSTTFVSDG 2463
TT +TR+ +S+TF G
Sbjct: 1382 GVRTTTGSTREPTSSTFQETG 1402
Score = 100 bits (249), Expect = 2e-20
Identities = 274/1345 (20%), Positives = 452/1345 (33%), Gaps = 164/1345 (12%)
Query: 522 TARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVIT 581
TA M T S + + TG + E T + S E+T+ E T
Sbjct: 108 TASMAGSESTISTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 167
Query: 582 VSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGKYLS 641
VS +T + D E+ +ASTT S + GS IT G +
Sbjct: 168 VSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSE-----------TITPSTAGSETT 216
Query: 642 TTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTH-RRERTETLIPEMRTDTYT 700
T T + T ++ +E T +ET + ++T
Sbjct: 217 TVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTA 276
Query: 701 DEIQEEITKSPFM--GKTEEEVFSGMK---LSTSLSEPIHVTESSVEMTKSFDFPTLITK 755
++ T + F KT +G + ST+ SEP + E T + TK
Sbjct: 277 ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 336
Query: 756 LSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPL 815
+S +EV + + T + TTV + + S+ S D +
Sbjct: 337 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 396
Query: 816 ESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDEDIAA 875
STE S + TT G + S T ++ T E ++ +
Sbjct: 397 ASTEGSET--------TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVS 448
Query: 876 HGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSK 935
T F+ TT++ E S + ++T + STEG T+ + +K
Sbjct: 449 ----TTVFETTTAS--TEGSEITIASTSDSETTTASTEGSETTTVTTAG-------SETK 495
Query: 936 PVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDE 995
T T+ GL + + TT + + +V V + SE+
Sbjct: 496 TAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENT 555
Query: 996 VLGEPSQDILVIDQTRLEATISPETMRTTKITEGT--TQEEFPWKEQTAEKPVPALSSTA 1053
+ + + T LE TT TEG+ T E T + + ++ A
Sbjct: 556 TVSTTGSETTTVSTTGLET--------TTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA 607
Query: 1054 WTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHK 1113
T T + + + + + ++ E + S T + + + G+ T
Sbjct: 608 STAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTV 667
Query: 1114 VKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKT 1173
TD T+ G + +++ TEGS TT +++ S +T T+ TT T
Sbjct: 668 STTDSETTMVSTTGSERTIT-------STEGSETTTVSATGSE-TTVSTEGSGTTTVSIT 719
Query: 1174 SLEDIDLG-SGLFEKPKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKK 1232
E + +G +TE E +T +T S+ TTA S + TT+A S T
Sbjct: 720 GSETTKVSTTGSETTTTSTEGSEITTASIT-GSETTTA--STEGSETTTASTEGSETTSA 776
Query: 1233 PPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTR 1292
G ETT+ E TT+ I+ ET T +S ++ T+
Sbjct: 777 -----STTGSETTTASTTSSE-------TTMASIMGSET---------TMASTIGSETTK 815
Query: 1293 PPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESK 1352
+ST +T F + I ++T +S
Sbjct: 816 --------------VSTASSKMTTVFTENSETTIASTTASETTTVS-------------- 847
Query: 1353 EDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYIN 1412
ET P +E S E E +++ TT ++
Sbjct: 848 ---TAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI---- 900
Query: 1413 GKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTE 1472
G T E +E E + ++ SE T ++T ++ +T
Sbjct: 901 GSETTTA---STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTA 957
Query: 1473 TTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQ 1532
+TE E+T T ET + G T E + TA +V+ +E
Sbjct: 958 STEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTA 1017
Query: 1533 AHEHTEPVSLFPEES-SGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSA 1591
+ E +E ++ S + ++ I +E T T+ YT ++
Sbjct: 1018 SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTT 1077
Query: 1592 SAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDT 1651
S SE V+ G+ + + + +E T V SGS T + A + T
Sbjct: 1078 STEGSETTTVSTTGS----ETTTASTADLETT---TVSTSGSG----TTTASTAGSETTT 1126
Query: 1652 MF---TMVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKFVSE 1708
++ + T S + T ++ +S T S TT++ VSE
Sbjct: 1127 VYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT-------------VSE 1173
Query: 1709 TDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELESPNVATSSDSG 1768
T T I S E TT T + +ST S E+ +T+
Sbjct: 1174 TTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS---------ETTTASTAGSET 1224
Query: 1769 TRKSFMSLTTPTQSEREMTDSTP--VFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLPR 1826
T S T T STP +ETNT +G++TT S+ ++ T+L
Sbjct: 1225 TTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAST---ASLEPTATSLTG 1281
Query: 1827 SPASVFMEQGSGEAAADPETTTVSS 1851
S + SG AA +TTVSS
Sbjct: 1282 SETTTVSITASGATAA---STTVSS 1303
Score = 99.4 bits (246), Expect = 5e-20
Identities = 285/1408 (20%), Positives = 459/1408 (32%), Gaps = 143/1408 (10%)
Query: 546 GHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVITVSKTSEDTIHTHLEDLESVSASTT 605
G T D + T + S E+T+ T S T +T ++ E+ +AST
Sbjct: 3 GSEATTTSTADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTA 62
Query: 606 VSPLIMPDNNGS-------SMDDWEERQTSG--RITEEFLGKYLSTTPFPSQHRTEIELF 656
S P GS S + T+G T G +T T I
Sbjct: 63 GSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSEST-ISTA 121
Query: 657 PYSGDKILVEGISTVIYPSLQTEMTHR----RERTETLIPEMRTDTYTDEIQEEITKSPF 712
+ + G T + ++ +E T E T T T T + E T
Sbjct: 122 GSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTA 181
Query: 713 MGKTEEEVFSGMKLSTSL---SEPIHVTESSVEMTKSFDFPTLITKLSAEPTEVRDMEED 769
+T +G +++T SE I + + E T + T +S +E
Sbjct: 182 DSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTA 241
Query: 770 FTATPGTTKYDENITTVLLAHGTLSVEAA----TVSKWSWDEDNTTSKPLESTEPSASSK 825
+ T + T V A +V A T + E NT T ++++
Sbjct: 242 HSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTG 301
Query: 826 LPPALLTTVGMNGKDKDIPSFTEDGADEFTLI----PDSTQKQLEEVTDEDIAAHGKFTI 881
+T G P+ E T+ P++T+ + A G TI
Sbjct: 302 FETTAASTTGSE------PTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETI 355
Query: 882 RFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSKPVSTVP 941
R S +T ++TT + TST+ + GS + ST
Sbjct: 356 RASTVGSETTTVSTTGSETTTASIMGSETSTD-----STTGSE---------TTTASTEG 401
Query: 942 QFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDEVLGEPS 1001
T+ EG + S+T TT V + + + + V + E
Sbjct: 402 SETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEG 461
Query: 1002 QDILVIDQTRLE-ATISPETMRTTKITEGTTQEEFPW---KEQTAEKPVPALSSTAWTPK 1057
+I + + E T S E TT +T ++ + + E T ++T +T
Sbjct: 462 SEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIG 521
Query: 1058 EAVTPLDEQEGDGSAYTVSEDELLT----GSERVPVLETTPVGKIDHSVSYPPGAVTEHK 1113
T + + +A + + E+ T GSE V T G +VS T
Sbjct: 522 SDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTT---GSETTTVSTTGLETTTTS 578
Query: 1114 VKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKT 1173
+ E+ T VS + TEGS TT +++ S +T T E TT
Sbjct: 579 TEGSEMTT--------VSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTA 630
Query: 1174 SLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKKP 1233
E + E A+ +T T S+ TT + TT + + T
Sbjct: 631 DSETTSASTTGSETTTASTTSSETTTASTEGSETTT-------VSTTDSETTMVSTTGSE 683
Query: 1234 PLIDREPGEETTSDMVIIGEST--SHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPT 1291
I G ETT+ E+T + TT I ET TT++
Sbjct: 684 RTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI 743
Query: 1292 RPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSES 1351
++ E + AST+ + S + + + SE+
Sbjct: 744 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSET 803
Query: 1352 KEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYI 1411
ET V +++ F + E + + +E A + + + +
Sbjct: 804 TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTA---- 859
Query: 1412 NGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNEST 1471
G TT E +E E + ++SSE+ T +T + +T
Sbjct: 860 -GSETTTTT--STEGSETTTASTEGSETTTASTESSETTT----------ATTIGSETTT 906
Query: 1472 ETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGH 1531
+TE E T T E SE T E E T T TE
Sbjct: 907 ASTEGSETT---TTSTEGSE----------TTTASTEGSEITTVSTTGSETTTASTEGSE 953
Query: 1532 QAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSA 1591
TE L ++G I ++ T T G E +++ T V ++
Sbjct: 954 TTTASTEGSELTTVSTTGSETITVSAE--GSETTTVTTMGSETTTASTAGSETTTVSTAG 1011
Query: 1592 S----AYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEE 1647
S A + E T+ +ST T + GS + +T E
Sbjct: 1012 SETTTASIEGSETTTVSSTGSETTTVST-----TGTETTITSTEGSETTTVTTAGSETTA 1066
Query: 1648 DEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKFVS 1707
T T ++ + T T+ T S T S ++ TT VS S + S
Sbjct: 1067 VYTTGSETTTTSTEGSETTTVSTTG-SETTTASTADLETTT---VSTSGSGTTTASTAGS 1122
Query: 1708 ETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQ-LILPFELESPNVAT-SS 1765
ET T S T E T T S+ +ST S+ + E+ V+T S
Sbjct: 1123 ETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGS 1182
Query: 1766 DSGTRKSFMSLTTPTQSE-REMTDSTPVFTETNTLENLGAQTTEHSSIHQPGVQEGLTTL 1824
++ T + S T T +E E T ++ +ET T G++TT
Sbjct: 1183 EATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETT----------------- 1225
Query: 1825 PRSPASVFMEQGSGEAAADPETTTVSS--FSLNVEYAIQAEKEVAGTLSPHVETTFSTEP 1882
AS + + ET+T SS N + I +E +A T S T T
Sbjct: 1226 ---TASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGS 1282
Query: 1883 TGLVLSTVMDRVVAENITQTSREIVISE 1910
+S A + T +S V+++
Sbjct: 1283 ETTTVSITASGATAASTTVSSTTFVLTK 1310
Score = 88.2 bits (217), Expect = 1e-16
Identities = 253/1199 (21%), Positives = 427/1199 (35%), Gaps = 185/1199 (15%)
Query: 1526 DTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPT 1585
+T V A +T S E++ + E+ + A + T ++T V+ + +
Sbjct: 25 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 84
Query: 1586 IVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQV--VELSGSSSIPITEGSG 1643
+ ++++A SE V+ G+ ++ ES + + V ++G+ + ++
Sbjct: 85 EITTTSTAG-SENTTVSSAGSGTTTASMAGSESTISTAGSETTTVSITGTETTMVSAMGS 143
Query: 1644 EAEEDEDTMF--TMVTDLSQRNTTDTLITLDTSRIITESFFEVPATT----IYPVSEQPS 1697
E + T T+ + TT + + +T+ T A+T + V S
Sbjct: 144 ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGS 203
Query: 1698 AKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELE 1757
+ P+ SET T S T E T TA + +ST S E
Sbjct: 204 ETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGS---------E 254
Query: 1758 SPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTE---TNTLENLGAQTTEHSSIHQ 1814
+ V+T+ T + S TT +E T++ FTE T T G +TT S+
Sbjct: 255 TTKVSTAGSETTVSTAGSETTAASTEDSETNTA--FTEDSKTTTASTTGFETTAAST--- 309
Query: 1815 PGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEV--AGTLSP 1872
T + AS + + + PETT VS+ S V A E A T+
Sbjct: 310 -------TGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS 362
Query: 1873 HVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPLEE 1932
TT ST + +++M + + T S S G+E ST
Sbjct: 363 ET-TTVSTTGSETTTASIMGSETSTDSTTGSETTTASTE------GSETTTASTEGSEAT 415
Query: 1933 DFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDT---QTSPSTVPTSVHISHISDSE-- 1987
S E +TVS ++ T EGS A T T+ ST + + I+ SDSE
Sbjct: 416 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 475
Query: 1988 -----GPSSTMVSTS------AFPWEEFTSSAEGSGEQLVTV--------SSSVVPVLPS 2028
G +T V+T+ A+ T++A +G + TV ++S +
Sbjct: 476 TASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETT 535
Query: 2029 AVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNF 2088
AV +++ EG E TV+ +T + T +E T E E+ TVST
Sbjct: 536 AVSATGSEMTTVSTEG-SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMT---TVSTTG 591
Query: 2089 PQTIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTET 2148
+T + S TT+ E + S +S T + DS+T T
Sbjct: 592 AETTTDSTEGSG-------------TTAASTAGSETTTVSTADSENTTASTADSET---T 635
Query: 2149 ELKTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATEKSHFFLA 2208
TT T T S+ E + +ST D S TT+ T
Sbjct: 636 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTD-------SETTMVSTTG------- 681
Query: 2209 TALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLPT 2268
+E +T + + E+T T+ + +E S GSG T
Sbjct: 682 ---------SERTITST--EGSETT---------TVSATGSETTVSTEGSGTT------T 715
Query: 2269 ESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVT 2328
S+ +E +++ T S+ +TS++ E A G S+T GS T
Sbjct: 716 VSITGSETTKVSTT----GSETTTTSTEGSEI-----TTASITG---SETTTASTEGSET 763
Query: 2329 STTLIE-----ILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSN 2383
+T E S TG+E T + T + A I S ++ S
Sbjct: 764 TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIG-SETTKVSTASSK 822
Query: 2384 KNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPSDLYYEPSGEGSGEVDIVDSFH 2443
+ E +ETT +ST A E T + S+ P+ E
Sbjct: 823 MTTVFTENSETTIASTT----------ASETTTVSTAGSETI--PASTAGSE-------- 862
Query: 2444 TSATTQATRQESSTTFVSDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSEQNKSSPDPT 2503
+ TT +T +TT ++GS E +A +++ ++ + + S T
Sbjct: 863 -TTTTTSTEGSETTTASTEGS-----ETTTASTESSETTTATTIGSETTTASTEGSETTT 916
Query: 2504 STLSNTVSYERSTDGSFQDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDLILTITESTI 2563
++ + + ST+GS E +T+ + T E + TE +
Sbjct: 917 TSTEGSETTTASTEGS--------EITTVSTTGSETT-----TASTEGSETTTASTEGSE 963
Query: 2564 LEILPELTSDKNTIIDIDHTKPVYEDILGMQTDIDTEVPSEPHDSNDESNDDSTQVQEIY 2623
L + T + + + ++ +G +T + SE + ++ +T E
Sbjct: 964 LTTV-STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGS 1022
Query: 2624 EAAVNLSLTEETFEGSADVLASYTQATHDESMTYEDRSQLDHMGFHFTTGIPAPSTETE 2682
E S ET S + +T T + + +TTG +T TE
Sbjct: 1023 ETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV-YTTGSETTTTSTE 1080
Score = 62.0 bits (149), Expect = 1e-08
Identities = 178/834 (21%), Positives = 275/834 (32%), Gaps = 120/834 (14%)
Query: 528 ESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVITVSKT-S 586
E+ T S + T G T+ D E ++ E T+ + E TVS T S
Sbjct: 643 ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 702
Query: 587 EDTIHTH--------LEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGK 638
E T+ T + E+ STT S GS + T+ IT G
Sbjct: 703 ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI-------TTASIT----GS 751
Query: 639 YLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRERTETLIPEMRTDT 698
+T EG T T T E T T T
Sbjct: 752 ETTTAS--------------------TEGSETT------TASTEGSETTSASTTGSETTT 785
Query: 699 YTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMTKSFDFPTLITKLSA 758
E T + MG ST SE V+ +S +MT F + T S
Sbjct: 786 -ASTTSSETTMASIMGS------ETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 838
Query: 759 EPTEVRDMEEDFTAT-PGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPLES 817
+E + + T P +T E TT S E + + S + TT+ ES
Sbjct: 839 TASETTTVSTAGSETIPASTAGSETTTTT-------STEGSETTTASTEGSETTTASTES 891
Query: 818 TEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDED---IA 874
+E + ++ + + TT G + S +G++ T + ++ T + +
Sbjct: 892 SETTTATTI-GSETTTASTEGSETTTTS--TEGSETTTASTEGSEITTVSTTGSETTTAS 948
Query: 875 AHGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLS 934
G T T ST +E +T+ + +E +E TM +
Sbjct: 949 TEGSET----TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSET 1004
Query: 935 KPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWG---------- 984
VST T+ +EG + SST TT V ++ T + I T+
Sbjct: 1005 TTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT--ETTITSTEGSETTTVTTAGS 1062
Query: 985 --VLVPSVPSEDEVLGEPSQDILVIDQTRLE-ATISPETMRTTKIT---EGTTQEEFPWK 1038
V + SE + + T E T S + TT ++ GTT
Sbjct: 1063 ETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGS 1122
Query: 1039 EQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKI 1098
E T + ++TA T T + + + + + E+ T V ETT V I
Sbjct: 1123 ETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT--VFTTVSETTTVSTI 1180
Query: 1099 DHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFS 1158
+ A +E + E T S + T GS TT ++S S +
Sbjct: 1181 GSEATTSSAAGSEATTTSTEGSETT-----TASTAGSETTTASTAGSETTTASTSGSETN 1235
Query: 1159 THITQLMEETTTEKTSLE---------DIDLGSGLFEKPKATELIEFSTIKVTVPSDITT 1209
T T E +T E + + S +P AT L T V++ + T
Sbjct: 1236 TACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGAT 1295
Query: 1210 AFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAK 1269
A +S TT ++ ++ +P G TT + S + P A
Sbjct: 1296 A-ASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAAS 1354
Query: 1270 ETETDI--DREYFTTSSPPA------------TQPTRPPTVEDKEAFGPQALST 1309
T I + TS+ A T TR PT + GP ++ T
Sbjct: 1355 HTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGT 1408
>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1521
Score = 124 bits (310), Expect = 2e-27
Identities = 303/1401 (21%), Positives = 479/1401 (34%), Gaps = 98/1401 (6%)
Query: 1093 TPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPR-IGPKVSLSPGPEQKYETEGSSTTGFT 1151
+P G VS +T E T++ G + G E T GS TT
Sbjct: 49 SPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT-V 107
Query: 1152 SSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDITTAF 1211
S +T ++ + ETTT T+ + + S + + T TTA
Sbjct: 108 SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAA 167
Query: 1212 SSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKET 1271
S+ TT S IT G ETT+ + G T+ V T E A
Sbjct: 168 STTGSEMTTVFTAGSETITPSTA------GSETTT-VSTAGSETTTVSTTGSETTTASTA 220
Query: 1272 ETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRE 1331
++ S T A ST +T F D
Sbjct: 221 HSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTG 280
Query: 1332 NKTGRMSDLS---VIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEE 1388
+T S + + SE+ ET V +E+ F E +
Sbjct: 281 FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET--IRAST 338
Query: 1389 NEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSE 1448
E + TTT S+ G T E A E+ S ++ SE
Sbjct: 339 VGSETTTVSTTGSETTTASIM---GSETSTDSTTGSETTTASTEGSETTTAS---TEGSE 392
Query: 1449 SDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHE 1508
+ T ++T + +T TE E+T T ET+ + G + E
Sbjct: 393 ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452
Query: 1509 EFESGTAKKGAESVTER--DTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARAT 1566
+ T +VT +T+ + T S E++ I ++ A +
Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-ASTEGS 511
Query: 1567 EVTFGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQ 1626
E T + T ++ S SE V+ G L T + E +
Sbjct: 512 ETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG-------LETTTTSTEGSEMT 564
Query: 1627 VVELSGS-SSIPITEGSGE-AEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEV 1684
V +G+ ++ TEGSG A + T V+ NTT + +T+ T
Sbjct: 565 TVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETT 624
Query: 1685 PATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEG---TTGTASTFEVY 1741
A+T + S + T VS TD+ + STT E+ EG TT +A+ E
Sbjct: 625 TASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684
Query: 1742 SSTQRSDQLILPFE-LESPNVATSSDSGTRKSF--MSLTTPTQSEREMTDSTPVFTETNT 1798
ST+ S + E+ V+T+ T S +TT + + E T ++ +ET T
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT 744
Query: 1799 LENLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFS--LNV 1856
G++TT S+ T+ + AS+ + + + ETT VS+ S +
Sbjct: 745 ASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT 804
Query: 1857 EYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPN 1916
+ +E +A T + T + + ST T+ S S E
Sbjct: 805 VFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETT 864
Query: 1917 YGA-EIRGFSTGFPLEED---FSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPS 1972
+ E +T + + S + E +T S ++ T EGS T + +
Sbjct: 865 TASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETT 924
Query: 1973 TVPTSVHISHISDSEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQK 2032
T T + + +EG T VST+ E T SAEGS VT S
Sbjct: 925 TASTEGSETTTASTEGSELTTVSTTGS--ETITVSAEGSETTTVTTMGSETTT------- 975
Query: 2033 FSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQTI 2092
+ TA S E TV+ +T TA +EG++ + TVST +T
Sbjct: 976 -ASTAGS-------ETTTVSTAGSETT---TASIEGSETTTVSSTGSETTTVSTTGTETT 1024
Query: 2093 EPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTET--EL 2150
+ S E V SETT+ E + S + S T + S+T T + +L
Sbjct: 1025 ITSTEGS--ETTTV-TTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL 1081
Query: 2151 KTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATE-KSHFFLAT 2209
+TT S + T + + + T G E+ T ++E + +
Sbjct: 1082 ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGS 1141
Query: 2210 ALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTE-LLFSGLGSGEEVLPTLPT 2268
+ T T S I E +T T +E S GS T +
Sbjct: 1142 EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGS 1201
Query: 2269 ESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFE-GSGSV 2327
E+ + NT S+ + SS E N A +G S+T I S
Sbjct: 1202 ETTTASTSGSETNTACTTGSETSTPSSAGSE-----TNTAFIIG---SETTIASTASLEP 1253
Query: 2328 TSTTLIEILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSNKNSS 2387
T+T+L TG+E TV+ + + TV + T + +N S
Sbjct: 1254 TATSL------TGSETTTVS---ITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1304
Query: 2388 TAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPS--DLYYEPSGEGS---GEVDIVDSF 2442
T +++ + A G +F SA + + SG G+ G +
Sbjct: 1305 GTRTTGTRLTASSSVTMAPGM----DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAH 1360
Query: 2443 HTSATTQATRQESSTTFVSDG 2463
TT +TR+ +S+TF G
Sbjct: 1361 GVRTTTGSTREPTSSTFQETG 1381
Score = 100 bits (249), Expect = 2e-20
Identities = 274/1345 (20%), Positives = 452/1345 (33%), Gaps = 164/1345 (12%)
Query: 522 TARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVIT 581
TA M T S + + TG + E T + S E+T+ E T
Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146
Query: 582 VSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGKYLS 641
VS +T + D E+ +ASTT S + GS IT G +
Sbjct: 147 VSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSE-----------TITPSTAGSETT 195
Query: 642 TTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTH-RRERTETLIPEMRTDTYT 700
T T + T ++ +E T +ET + ++T
Sbjct: 196 TVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTA 255
Query: 701 DEIQEEITKSPFM--GKTEEEVFSGMK---LSTSLSEPIHVTESSVEMTKSFDFPTLITK 755
++ T + F KT +G + ST+ SEP + E T + TK
Sbjct: 256 ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315
Query: 756 LSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPL 815
+S +EV + + T + TTV + + S+ S D +
Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 375
Query: 816 ESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDEDIAA 875
STE S + TT G + S T ++ T E ++ +
Sbjct: 376 ASTEGSET--------TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVS 427
Query: 876 HGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSK 935
T F+ TT++ E S + ++T + STEG T+ + +K
Sbjct: 428 ----TTVFETTTAS--TEGSEITIASTSDSETTTASTEGSETTTVTTAG-------SETK 474
Query: 936 PVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDE 995
T T+ GL + + TT + + +V V + SE+
Sbjct: 475 TAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENT 534
Query: 996 VLGEPSQDILVIDQTRLEATISPETMRTTKITEGT--TQEEFPWKEQTAEKPVPALSSTA 1053
+ + + T LE TT TEG+ T E T + + ++ A
Sbjct: 535 TVSTTGSETTTVSTTGLET--------TTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA 586
Query: 1054 WTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHK 1113
T T + + + + + ++ E + S T + + + G+ T
Sbjct: 587 STAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTV 646
Query: 1114 VKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKT 1173
TD T+ G + +++ TEGS TT +++ S +T T+ TT T
Sbjct: 647 STTDSETTMVSTTGSERTIT-------STEGSETTTVSATGSE-TTVSTEGSGTTTVSIT 698
Query: 1174 SLEDIDLG-SGLFEKPKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKK 1232
E + +G +TE E +T +T S+ TTA S + TT+A S T
Sbjct: 699 GSETTKVSTTGSETTTTSTEGSEITTASIT-GSETTTA--STEGSETTTASTEGSETTSA 755
Query: 1233 PPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTR 1292
G ETT+ E TT+ I+ ET T +S ++ T+
Sbjct: 756 -----STTGSETTTASTTSSE-------TTMASIMGSET---------TMASTIGSETTK 794
Query: 1293 PPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESK 1352
+ST +T F + I ++T +S
Sbjct: 795 --------------VSTASSKMTTVFTENSETTIASTTASETTTVS-------------- 826
Query: 1353 EDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYIN 1412
ET P +E S E E +++ TT ++
Sbjct: 827 ---TAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI---- 879
Query: 1413 GKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTE 1472
G T E +E E + ++ SE T ++T ++ +T
Sbjct: 880 GSETTTA---STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTA 936
Query: 1473 TTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQ 1532
+TE E+T T ET + G T E + TA +V+ +E
Sbjct: 937 STEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTA 996
Query: 1533 AHEHTEPVSLFPEES-SGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSA 1591
+ E +E ++ S + ++ I +E T T+ YT ++
Sbjct: 997 SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTT 1056
Query: 1592 SAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDT 1651
S SE V+ G+ + + + +E T V SGS T + A + T
Sbjct: 1057 STEGSETTTVSTTGS----ETTTASTADLETT---TVSTSGSG----TTTASTAGSETTT 1105
Query: 1652 MF---TMVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKFVSE 1708
++ + T S + T ++ +S T S TT++ VSE
Sbjct: 1106 VYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT-------------VSE 1152
Query: 1709 TDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELESPNVATSSDSG 1768
T T I S E TT T + +ST S E+ +T+
Sbjct: 1153 TTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS---------ETTTASTAGSET 1203
Query: 1769 TRKSFMSLTTPTQSEREMTDSTP--VFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLPR 1826
T S T T STP +ETNT +G++TT S+ ++ T+L
Sbjct: 1204 TTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAST---ASLEPTATSLTG 1260
Query: 1827 SPASVFMEQGSGEAAADPETTTVSS 1851
S + SG AA +TTVSS
Sbjct: 1261 SETTTVSITASGATAA---STTVSS 1282
Score = 98.6 bits (244), Expect = 9e-20
Identities = 288/1333 (21%), Positives = 455/1333 (34%), Gaps = 171/1333 (12%)
Query: 566 SDESTLIFDQIPEVITVSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEER 625
S E+T+ T S T +T ++ E+ +AST S P GS
Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGS-------- 53
Query: 626 QTSGRITEEFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRE 685
QT+ G ++TT T + + G T + + T
Sbjct: 54 QTT---IVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSIT 110
Query: 686 RTE-TLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMT 744
TE T++ M ++T T+ T ST+ SE V+ E T
Sbjct: 111 GTETTMVSAMGSETTTNSTTSSET---------------TVTSTAGSETTTVSTVGSETT 155
Query: 745 KSFDFPTLITKLSAEPTEVRDMEEDFTA-----TPGTTKYDENITTVLLAHGTLSVEAAT 799
++ T ++ +A T +M FTA TP T TTV A + + T
Sbjct: 156 TAY---TADSETTAASTTGSEMTTVFTAGSETITPSTA--GSETTTVSTAGSETTTVSTT 210
Query: 800 VSKWSWDEDNTTSKPLESTEPSASSKLPPA-LLTTVGMNGKDKDIPSFTEDGADEFTLIP 858
S+ + + ST S ++K+ A TTV G + S TED
Sbjct: 211 GSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAAS-TEDSETNTAFTE 269
Query: 859 DSTQKQLEEVTDEDIAAHGKFTIRFQPTTSTGIAEKSTLRDSTTEE--KVPPITSTEGQV 916
DS E AA T +PT ++ + ++T+ + E KV +S V
Sbjct: 270 DSKTTTASTTGFETTAAS---TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV 326
Query: 917 YA----TMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHT 972
+A T+ S +G + VST T+ + G + S+T TT +
Sbjct: 327 FAAGSETIRASTVGSE-----TTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTE-- 379
Query: 973 IPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEATI--SPETMRTTKITEGT 1030
SE + + T E T ++ TT TEG+
Sbjct: 380 ------------------GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGS 421
Query: 1031 TQEEFPWKEQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVL 1090
E TA ++TA T +T + S+ E T S
Sbjct: 422 --------EMTAVSTTVFETTTASTEGSEIT----------IASTSDSETTTASTEGSET 463
Query: 1091 ETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGF 1150
T + +Y G+ T T T IG + + TEGS TT
Sbjct: 464 TTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA-------STEGSETTAV 516
Query: 1151 TSSLSPFSTHITQLMEETTTEKTSLEDIDLG-SGLFEKPKATELIEFSTIKVTVPSDITT 1209
+++ S +T T+ E TT T E + +GL +TE E +T+ T T
Sbjct: 517 SATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT---GAET 573
Query: 1210 AFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAK 1269
S + TT+A S T D E +T+D ST+ TT ++
Sbjct: 574 TTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632
Query: 1270 ETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEV 1329
T + TT S ++ T T + S ++T ++
Sbjct: 633 TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS------ 686
Query: 1330 RENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEEN 1389
+ + +S+ G SE+ + ET +EI E +E +
Sbjct: 687 --TEGSGTTTVSITG----SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740
Query: 1390 EEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSES 1449
E TTT S + G + E A E+ S S+++ +
Sbjct: 741 E------------TTTASTE---GSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785
Query: 1450 DTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEE 1509
T + ++T + +T TE+ E T T ET+ + G + P E
Sbjct: 786 ST---IGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS-ETIPASTAGSE 841
Query: 1510 FESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVT 1569
+ T+ +G+E+ T TE TE E++ I E+ T T
Sbjct: 842 TTTTTSTEGSETTT-ASTEGSETTTASTE-----SSETTTATTIGSET-------TTAST 888
Query: 1570 FGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPW---PDDLLSTKESWVEATPRQ 1626
G E T+ T T ++AS SE V+ G+ + T + E +
Sbjct: 889 EGSE----TTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELT 944
Query: 1627 VVELSGSSSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEVPA 1686
V +GS +I ++ G TM + T S + T ++ S T S
Sbjct: 945 TVSTTGSETITVS-AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET 1003
Query: 1687 TTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQR 1746
TT+ + T VS T T I+ST E G+ TA +T
Sbjct: 1004 TTVSSTGSE-------TTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTT 1056
Query: 1747 SDQLILPFELESPNVATSSDSGTRKSFMSL--TTPTQSEREMTDSTPVFTETNTLENLGA 1804
S + E+ V+T+ T S L TT + S T ++ +ET T+ G+
Sbjct: 1057 STE-----GSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111
Query: 1805 QTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEK 1864
+TT S+ T+ + AS + + ETTTVS+ + A
Sbjct: 1112 KTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGS 1171
Query: 1865 EVAGTLSPHVETT 1877
E T + ETT
Sbjct: 1172 EATTTSTEGSETT 1184
Score = 87.4 bits (215), Expect = 2e-16
Identities = 253/1199 (21%), Positives = 427/1199 (35%), Gaps = 185/1199 (15%)
Query: 1526 DTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPT 1585
+T V A +T S E++ + E+ + A + T ++T V+ + +
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 1586 IVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQV--VELSGSSSIPITEGSG 1643
+ ++++A SE V+ G+ ++ E+ V + V ++G+ + ++
Sbjct: 64 EITTTSTAG-SENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122
Query: 1644 EAEEDEDTMF--TMVTDLSQRNTTDTLITLDTSRIITESFFEVPATT----IYPVSEQPS 1697
E + T T+ + TT + + +T+ T A+T + V S
Sbjct: 123 ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGS 182
Query: 1698 AKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELE 1757
+ P+ SET T S T E T TA + +ST S E
Sbjct: 183 ETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGS---------E 233
Query: 1758 SPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTE---TNTLENLGAQTTEHSSIHQ 1814
+ V+T+ T + S TT +E T++ FTE T T G +TT S+
Sbjct: 234 TTKVSTAGSETTVSTAGSETTAASTEDSETNTA--FTEDSKTTTASTTGFETTAAST--- 288
Query: 1815 PGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEV--AGTLSP 1872
T + AS + + + PETT VS+ S V A E A T+
Sbjct: 289 -------TGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS 341
Query: 1873 HVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPLEE 1932
TT ST + +++M + + T S S G+E ST
Sbjct: 342 ET-TTVSTTGSETTTASIMGSETSTDSTTGSETTTASTE------GSETTTASTEGSEAT 394
Query: 1933 DFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDT---QTSPSTVPTSVHISHISDSE-- 1987
S E +TVS ++ T EGS A T T+ ST + + I+ SDSE
Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454
Query: 1988 -----GPSSTMVSTS------AFPWEEFTSSAEGSGEQLVTV--------SSSVVPVLPS 2028
G +T V+T+ A+ T++A +G + TV ++S +
Sbjct: 455 TASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514
Query: 2029 AVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNF 2088
AV +++ EG E TV+ +T + T +E T E E+ TVST
Sbjct: 515 AVSATGSEMTTVSTEG-SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMT---TVSTTG 570
Query: 2089 PQTIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTET 2148
+T + S TT+ E + S +S T + DS+T T
Sbjct: 571 AETTTDSTEGSG-------------TTAASTAGSETTTVSTADSENTTASTADSET---T 614
Query: 2149 ELKTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATEKSHFFLA 2208
TT T T S+ E + +ST D S TT+ T
Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTD-------SETTMVSTTG------- 660
Query: 2209 TALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLPT 2268
+E +T + + E+T T+ + +E S GSG T
Sbjct: 661 ---------SERTITST--EGSETT---------TVSATGSETTVSTEGSGTT------T 694
Query: 2269 ESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVT 2328
S+ +E +++ T S+ +TS++ E A G S+T GS T
Sbjct: 695 VSITGSETTKVSTT----GSETTTTSTEGSEI-----TTASITG---SETTTASTEGSET 742
Query: 2329 STTLIE-----ILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSN 2383
+T E S TG+E T + T + A I S ++ S
Sbjct: 743 TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIG-SETTKVSTASSK 801
Query: 2384 KNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPSDLYYEPSGEGSGEVDIVDSFH 2443
+ E +ETT +ST A E T + S+ P+ E
Sbjct: 802 MTTVFTENSETTIASTT----------ASETTTVSTAGSETI--PASTAGSE-------- 841
Query: 2444 TSATTQATRQESSTTFVSDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSEQNKSSPDPT 2503
+ TT +T +TT ++GS E +A +++ ++ + + S T
Sbjct: 842 -TTTTTSTEGSETTTASTEGS-----ETTTASTESSETTTATTIGSETTTASTEGSETTT 895
Query: 2504 STLSNTVSYERSTDGSFQDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDLILTITESTI 2563
++ + + ST+GS E +T+ + T E + TE +
Sbjct: 896 TSTEGSETTTASTEGS--------EITTVSTTGSETT-----TASTEGSETTTASTEGSE 942
Query: 2564 LEILPELTSDKNTIIDIDHTKPVYEDILGMQTDIDTEVPSEPHDSNDESNDDSTQVQEIY 2623
L + T + + + ++ +G +T + SE + ++ +T E
Sbjct: 943 LTTV-STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGS 1001
Query: 2624 EAAVNLSLTEETFEGSADVLASYTQATHDESMTYEDRSQLDHMGFHFTTGIPAPSTETE 2682
E S ET S + +T T + + +TTG +T TE
Sbjct: 1002 ETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV-YTTGSETTTTSTE 1059
Score = 62.0 bits (149), Expect = 1e-08
Identities = 178/834 (21%), Positives = 275/834 (32%), Gaps = 120/834 (14%)
Query: 528 ESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVITVSKT-S 586
E+ T S + T G T+ D E ++ E T+ + E TVS T S
Sbjct: 622 ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 681
Query: 587 EDTIHTH--------LEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGK 638
E T+ T + E+ STT S GS + T+ IT G
Sbjct: 682 ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI-------TTASIT----GS 730
Query: 639 YLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRERTETLIPEMRTDT 698
+T EG T T T E T T T
Sbjct: 731 ETTTAS--------------------TEGSETT------TASTEGSETTSASTTGSETTT 764
Query: 699 YTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMTKSFDFPTLITKLSA 758
E T + MG ST SE V+ +S +MT F + T S
Sbjct: 765 -ASTTSSETTMASIMGS------ETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817
Query: 759 EPTEVRDMEEDFTAT-PGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPLES 817
+E + + T P +T E TT S E + + S + TT+ ES
Sbjct: 818 TASETTTVSTAGSETIPASTAGSETTTTT-------STEGSETTTASTEGSETTTASTES 870
Query: 818 TEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDED---IA 874
+E + ++ + + TT G + S +G++ T + ++ T + +
Sbjct: 871 SETTTATTI-GSETTTASTEGSETTTTS--TEGSETTTASTEGSEITTVSTTGSETTTAS 927
Query: 875 AHGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLS 934
G T T ST +E +T+ + +E +E TM +
Sbjct: 928 TEGSET----TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSET 983
Query: 935 KPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWG---------- 984
VST T+ +EG + SST TT V ++ T + I T+
Sbjct: 984 TTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT--ETTITSTEGSETTTVTTAGS 1041
Query: 985 --VLVPSVPSEDEVLGEPSQDILVIDQTRLE-ATISPETMRTTKIT---EGTTQEEFPWK 1038
V + SE + + T E T S + TT ++ GTT
Sbjct: 1042 ETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGS 1101
Query: 1039 EQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKI 1098
E T + ++TA T T + + + + + E+ T V ETT V I
Sbjct: 1102 ETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT--VFTTVSETTTVSTI 1159
Query: 1099 DHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFS 1158
+ A +E + E T S + T GS TT ++S S +
Sbjct: 1160 GSEATTSSAAGSEATTTSTEGSETT-----TASTAGSETTTASTAGSETTTASTSGSETN 1214
Query: 1159 THITQLMEETTTEKTSLE---------DIDLGSGLFEKPKATELIEFSTIKVTVPSDITT 1209
T T E +T E + + S +P AT L T V++ + T
Sbjct: 1215 TACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGAT 1274
Query: 1210 AFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAK 1269
A +S TT ++ ++ +P G TT + S + P A
Sbjct: 1275 A-ASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAAS 1333
Query: 1270 ETETDI--DREYFTTSSPPA------------TQPTRPPTVEDKEAFGPQALST 1309
T I + TS+ A T TR PT + GP ++ T
Sbjct: 1334 HTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGT 1387
>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1612
Score = 124 bits (310), Expect = 2e-27
Identities = 298/1402 (21%), Positives = 474/1402 (33%), Gaps = 100/1402 (7%)
Query: 1093 TPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPR-IGPKVSLSPGPEQKYETEGSSTTGFT 1151
+P G VS +T E T++ G + G E T GS TT
Sbjct: 49 SPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT-V 107
Query: 1152 SSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDITTAF 1211
S +T ++ + ETTT T+ + + S + + T TTA
Sbjct: 108 SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAA 167
Query: 1212 SSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKET 1271
S+ TT S IT G ETT+ + G T+ V T E A
Sbjct: 168 STTGSEMTTVFTAGSETITPSTA------GSETTT-VSTAGSETTTVSTTGSETTTASTA 220
Query: 1272 ETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRE 1331
++ S T A ST +T F D
Sbjct: 221 HSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTG 280
Query: 1332 NKTGRMSDLS---VIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEE 1388
+T S + + SE+ ET V +E+ F E +
Sbjct: 281 FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET--IRAST 338
Query: 1389 NEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSE 1448
E + TTT S+ G T E A E+ S ++ SE
Sbjct: 339 VGSETTTVSTTGSETTTASIM---GSETSTDSTTGSETTTASTEGSETTTAS---TEGSE 392
Query: 1449 SDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHE 1508
+ T ++T + +T TE E+T T ET+ + G + E
Sbjct: 393 ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452
Query: 1509 EFESGTAKKGAESVTER--DTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARAT 1566
+ T +VT +T+ + T S E++ I ++ A +
Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-ASTEGS 511
Query: 1567 EVTFGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQ 1626
E T + T ++ S SE V+ G L T + E +
Sbjct: 512 ETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG-------LETTTTSTEGSEMT 564
Query: 1627 VVELSGS-SSIPITEGSGE-AEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEV 1684
V +G+ ++ TEGSG A + T V+ NTT + +T+ T
Sbjct: 565 TVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETT 624
Query: 1685 PATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEG---TTGTASTFEVY 1741
A+T + S + T VS TD+ + STT E+ EG TT +A+ E
Sbjct: 625 TASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684
Query: 1742 SSTQRSDQLILPFE-LESPNVATSSDSGTRKSF--MSLTTPTQSEREMTDSTPVFTETNT 1798
ST+ S + E+ V+T+ T S +TT + + E T ++ +ET T
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT 744
Query: 1799 LENLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFS--LNV 1856
G++TT S+ T+ + AS+ + + + ETT VS+ S +
Sbjct: 745 ASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT 804
Query: 1857 EYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPN 1916
+ +E +A T + T + + ST T+ S S E
Sbjct: 805 VFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETT 864
Query: 1917 YGA-EIRGFSTGFPLEED---FSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPS 1972
+ E +T + + S + E +T S ++ T EGS T + +
Sbjct: 865 TASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETT 924
Query: 1973 TVPTSVHISHISDSEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQK 2032
T T + + +EG T VST+ E T SAEGS VT S
Sbjct: 925 TASTEGSETTTASTEGSELTTVSTTGS--ETITVSAEGSETTTVTTMGSETTT------- 975
Query: 2033 FSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQTI 2092
+ TA S E TV+ +T TA +EG++ + TVST +T
Sbjct: 976 -ASTAGS-------ETTTVSTAGSETT---TASIEGSETTTVSSTGSETTTVSTTGTETT 1024
Query: 2093 EPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTET--EL 2150
+ S E V SETT+ E + S + S T + S+T T + +L
Sbjct: 1025 ITSTEGS--ETTTV-TTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL 1081
Query: 2151 KTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATE-KSHFFLAT 2209
+TT S + T + + + T G E+ T ++E + +
Sbjct: 1082 ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGS 1141
Query: 2210 ALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTE-LLFSGLGSGEEVLPTLPT 2268
+ T T S I E +T T +E S GS T +
Sbjct: 1142 EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGS 1201
Query: 2269 ESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVT 2328
E+ + NT S+ + SS G + I ++
Sbjct: 1202 ETTTASTSGSETNTACTTGSETSTPSS---------------AGSETNTAFIIGSESTIA 1246
Query: 2329 STTLIE--ILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSNKNS 2386
ST +E S TG+E TV+ + + TV + T + +N
Sbjct: 1247 STASLEPTATSLTGSETTTVS---ITASGATAASTTVSSTTFVLTKATDVSIQPITNTPM 1303
Query: 2387 STAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPS--DLYYEPSGEGS---GEVDIVDS 2441
S T +++ + A G +F SA + + SG G+ G +
Sbjct: 1304 SGTRTTGTRLTASSSVTMAPGM----DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSA 1359
Query: 2442 FHTSATTQATRQESSTTFVSDG 2463
TT +TR+ +S+TF G
Sbjct: 1360 HGVRTTTGSTREPTSSTFQETG 1381
Score = 99.8 bits (247), Expect = 4e-20
Identities = 328/1527 (21%), Positives = 520/1527 (34%), Gaps = 225/1527 (14%)
Query: 566 SDESTLIFDQIPEVITVSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEER 625
S E+T+ T S T +T ++ E+ +AST S P GS
Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGS-------- 53
Query: 626 QTSGRITEEFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRE 685
QT+ G ++TT T + + G T + + T
Sbjct: 54 QTT---IVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSIT 110
Query: 686 RTE-TLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMT 744
TE T++ M ++T T+ T ST+ SE V+ E T
Sbjct: 111 GTETTMVSAMGSETTTNSTTSSET---------------TVTSTAGSETTTVSTVGSETT 155
Query: 745 KSFDFPTLITKLSAEPTEVRDMEEDFTA-----TPGTTKYDENITTVLLAHGTLSVEAAT 799
++ T ++ +A T +M FTA TP T TTV A + + T
Sbjct: 156 TAY---TADSETTAASTTGSEMTTVFTAGSETITPSTA--GSETTTVSTAGSETTTVSTT 210
Query: 800 VSKWSWDEDNTTSKPLESTEPSASSKLPPA-LLTTVGMNGKDKDIPSFTEDGADEFTLIP 858
S+ + + ST S ++K+ A TTV G + S TED
Sbjct: 211 GSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAAS-TEDSETNTAFTE 269
Query: 859 DSTQKQLEEVTDEDIAAHGKFTIRFQPTTSTGIAEKSTLRDSTTEE--KVPPITSTEGQV 916
DS E AA T +PT ++ + ++T+ + E KV +S V
Sbjct: 270 DSKTTTASTTGFETTAAS---TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV 326
Query: 917 YA----TMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHT 972
+A T+ S +G + VST T+ + G + S+T TT +
Sbjct: 327 FAAGSETIRASTVGSE-----TTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTE-- 379
Query: 973 IPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEATI--SPETMRTTKITEGT 1030
SE + + T E T ++ TT TEG+
Sbjct: 380 ------------------GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGS 421
Query: 1031 TQEEFPWKEQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVL 1090
E TA ++TA T +T + S+ E T S
Sbjct: 422 --------EMTAVSTTVFETTTASTEGSEIT----------IASTSDSETTTASTEGSET 463
Query: 1091 ETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGF 1150
T + +Y G+ T T T IG + + TEGS TT
Sbjct: 464 TTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA-------STEGSETTAV 516
Query: 1151 TSSLSPFSTHITQLMEETTTEKTSLEDIDLG-SGLFEKPKATELIEFSTIKVTVPSDITT 1209
+++ S +T T+ E TT T E + +GL +TE E +T+ T T
Sbjct: 517 SATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT---GAET 573
Query: 1210 AFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAK 1269
S + TT+A S T D E +T+D ST+ TT ++
Sbjct: 574 TTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632
Query: 1270 ETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEV 1329
T + TT S ++ T T + S ++T ++
Sbjct: 633 TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS------ 686
Query: 1330 RENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEEN 1389
+ + +S+ G SE+ + ET +EI E +E +
Sbjct: 687 --TEGSGTTTVSITG----SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740
Query: 1390 EEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSES 1449
E TTT S + G + E A E+ S S+++ +
Sbjct: 741 E------------TTTASTE---GSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785
Query: 1450 DTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEE 1509
T + ++T + +T TE+ E T T ET+ + G + P E
Sbjct: 786 ST---IGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS-ETIPASTAGSE 841
Query: 1510 FESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVT 1569
+ T+ +G+E+ T TE TE E++ I E+ T T
Sbjct: 842 TTTTTSTEGSETTT-ASTEGSETTTASTE-----SSETTTATTIGSET-------TTAST 888
Query: 1570 FGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPW---PDDLLSTKESWVEATPRQ 1626
G E T+ T T ++AS SE V+ G+ + T + E +
Sbjct: 889 EGSE----TTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELT 944
Query: 1627 VVELSGSSSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEVPA 1686
V +GS +I ++ G TM + T S + T ++ S T S
Sbjct: 945 TVSTTGSETITVS-AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET 1003
Query: 1687 TTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQR 1746
TT+ + T VS T T I+ST E TT + T VY++
Sbjct: 1004 TTVSSTGSE-------TTTVSTTGTETTITSTEGSETTTV----TTAGSETTAVYTT--- 1049
Query: 1747 SDQLILPFELESPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTETNTLENLGAQT 1806
T+S G+ TT + + E T ++ ET T+ G+ T
Sbjct: 1050 -----------GSETTTTSTEGS-----ETTTVSTTGSETTTASTADLETTTVSTSGSGT 1093
Query: 1807 TEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEV 1866
T S+ G + + S + +GS E TTVS+ S +E
Sbjct: 1094 TTAST---AGSETTTVYITGSKTTTASTEGS-------EATTVSTTS--------SETTT 1135
Query: 1867 AGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFST 1926
A T + T F+T +ST+ T+ SE G+E ST
Sbjct: 1136 ASTTGSEMTTVFTTVSETTTVSTIGSEA-------TTSSAAGSEATTTSTEGSETTTAST 1188
Query: 1927 GFPLEEDFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVPTSVHISHISDS 1986
S E +T S ++ T GS +T T PS+ + + + I S
Sbjct: 1189 AGSETTTASTAGSETTTASTSGSETNTACTTGS------ETST-PSSAGSETNTAFIIGS 1241
Query: 1987 EGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQKFSGTASSIIDEGLG 2046
E ST+ ST++ E +S GS V++++S + V + + D +
Sbjct: 1242 E---STIASTASL--EPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQ 1296
Query: 2047 EVGTVNEIDRRST-ILPTAEVEGTKAP 2072
+ R+T TA T AP
Sbjct: 1297 PITNTPMSGTRTTGTRLTASSSVTMAP 1323
Score = 99.0 bits (245), Expect = 7e-20
Identities = 273/1345 (20%), Positives = 452/1345 (33%), Gaps = 164/1345 (12%)
Query: 522 TARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVIT 581
TA M T S + + TG + E T + S E+T+ E T
Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146
Query: 582 VSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGKYLS 641
VS +T + D E+ +ASTT S + GS IT G +
Sbjct: 147 VSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSE-----------TITPSTAGSETT 195
Query: 642 TTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTH-RRERTETLIPEMRTDTYT 700
T T + T ++ +E T +ET + ++T
Sbjct: 196 TVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTA 255
Query: 701 DEIQEEITKSPFM--GKTEEEVFSGMK---LSTSLSEPIHVTESSVEMTKSFDFPTLITK 755
++ T + F KT +G + ST+ SEP + E T + TK
Sbjct: 256 ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315
Query: 756 LSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPL 815
+S +EV + + T + TTV + + S+ S D +
Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 375
Query: 816 ESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDEDIAA 875
STE S + TT G + S T ++ T E ++ +
Sbjct: 376 ASTEGSET--------TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVS 427
Query: 876 HGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSK 935
T F+ TT++ E S + ++T + STEG T+ + +K
Sbjct: 428 ----TTVFETTTAS--TEGSEITIASTSDSETTTASTEGSETTTVTTAG-------SETK 474
Query: 936 PVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDE 995
T T+ GL + + TT + + +V V + SE+
Sbjct: 475 TAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENT 534
Query: 996 VLGEPSQDILVIDQTRLEATISPETMRTTKITEGT--TQEEFPWKEQTAEKPVPALSSTA 1053
+ + + T LE TT TEG+ T E T + + ++ A
Sbjct: 535 TVSTTGSETTTVSTTGLET--------TTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA 586
Query: 1054 WTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHK 1113
T T + + + + + ++ E + S T + + + G+ T
Sbjct: 587 STAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTV 646
Query: 1114 VKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKT 1173
TD T+ G + +++ TEGS TT +++ S +T T+ TT T
Sbjct: 647 STTDSETTMVSTTGSERTIT-------STEGSETTTVSATGSE-TTVSTEGSGTTTVSIT 698
Query: 1174 SLEDIDLG-SGLFEKPKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKK 1232
E + +G +TE E +T +T S+ TTA S + TT+A S T
Sbjct: 699 GSETTKVSTTGSETTTTSTEGSEITTASIT-GSETTTA--STEGSETTTASTEGSETTSA 755
Query: 1233 PPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTR 1292
G ETT+ E TT+ I+ ET T +S ++ T+
Sbjct: 756 -----STTGSETTTASTTSSE-------TTMASIMGSET---------TMASTIGSETTK 794
Query: 1293 PPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESK 1352
+ST +T F + I ++T +S
Sbjct: 795 --------------VSTASSKMTTVFTENSETTIASTTASETTTVS-------------- 826
Query: 1353 EDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYIN 1412
ET P +E S E E +++ TT ++
Sbjct: 827 ---TAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI---- 879
Query: 1413 GKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTE 1472
G T E +E E + ++ SE T ++T ++ +T
Sbjct: 880 GSETTTA---STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTA 936
Query: 1473 TTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQ 1532
+TE E+T T ET + G T E + TA +V+ +E
Sbjct: 937 STEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTA 996
Query: 1533 AHEHTEPVSLFPEES-SGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSA 1591
+ E +E ++ S + ++ I +E T T+ YT ++
Sbjct: 997 SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTT 1056
Query: 1592 SAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDT 1651
S SE V+ G+ + + + +E T V SGS T + A + T
Sbjct: 1057 STEGSETTTVSTTGS----ETTTASTADLETT---TVSTSGSG----TTTASTAGSETTT 1105
Query: 1652 MF---TMVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKFVSE 1708
++ + T S + T ++ +S T S TT++ VSE
Sbjct: 1106 VYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT-------------VSE 1152
Query: 1709 TDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELESPNVATSSDSG 1768
T T I S E TT T + +ST S E+ +T+
Sbjct: 1153 TTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS---------ETTTASTAGSET 1203
Query: 1769 TRKSFMSLTTPTQSEREMTDSTP--VFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLPR 1826
T S T T STP +ETNT +G+++T S+ ++ T+L
Sbjct: 1204 TTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIAST---ASLEPTATSLTG 1260
Query: 1827 SPASVFMEQGSGEAAADPETTTVSS 1851
S + SG AA +TTVSS
Sbjct: 1261 SETTTVSITASGATAA---STTVSS 1282
Score = 87.4 bits (215), Expect = 2e-16
Identities = 253/1199 (21%), Positives = 427/1199 (35%), Gaps = 185/1199 (15%)
Query: 1526 DTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPT 1585
+T V A +T S E++ + E+ + A + T ++T V+ + +
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 1586 IVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQV--VELSGSSSIPITEGSG 1643
+ ++++A SE V+ G+ ++ E+ V + V ++G+ + ++
Sbjct: 64 EITTTSTAG-SENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122
Query: 1644 EAEEDEDTMF--TMVTDLSQRNTTDTLITLDTSRIITESFFEVPATT----IYPVSEQPS 1697
E + T T+ + TT + + +T+ T A+T + V S
Sbjct: 123 ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGS 182
Query: 1698 AKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELE 1757
+ P+ SET T S T E T TA + +ST S E
Sbjct: 183 ETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGS---------E 233
Query: 1758 SPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTE---TNTLENLGAQTTEHSSIHQ 1814
+ V+T+ T + S TT +E T++ FTE T T G +TT S+
Sbjct: 234 TTKVSTAGSETTVSTAGSETTAASTEDSETNTA--FTEDSKTTTASTTGFETTAAST--- 288
Query: 1815 PGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEV--AGTLSP 1872
T + AS + + + PETT VS+ S V A E A T+
Sbjct: 289 -------TGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS 341
Query: 1873 HVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPLEE 1932
TT ST + +++M + + T S S G+E ST
Sbjct: 342 ET-TTVSTTGSETTTASIMGSETSTDSTTGSETTTASTE------GSETTTASTEGSEAT 394
Query: 1933 DFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDT---QTSPSTVPTSVHISHISDSE-- 1987
S E +TVS ++ T EGS A T T+ ST + + I+ SDSE
Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454
Query: 1988 -----GPSSTMVSTS------AFPWEEFTSSAEGSGEQLVTV--------SSSVVPVLPS 2028
G +T V+T+ A+ T++A +G + TV ++S +
Sbjct: 455 TASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514
Query: 2029 AVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNF 2088
AV +++ EG E TV+ +T + T +E T E E+ TVST
Sbjct: 515 AVSATGSEMTTVSTEG-SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMT---TVSTTG 570
Query: 2089 PQTIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTET 2148
+T + S TT+ E + S +S T + DS+T T
Sbjct: 571 AETTTDSTEGSG-------------TTAASTAGSETTTVSTADSENTTASTADSET---T 614
Query: 2149 ELKTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATEKSHFFLA 2208
TT T T S+ E + +ST D S TT+ T
Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTD-------SETTMVSTTG------- 660
Query: 2209 TALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLPT 2268
+E +T + + E+T T+ + +E S GSG T
Sbjct: 661 ---------SERTITST--EGSETT---------TVSATGSETTVSTEGSGTT------T 694
Query: 2269 ESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVT 2328
S+ +E +++ T S+ +TS++ E A G S+T GS T
Sbjct: 695 VSITGSETTKVSTT----GSETTTTSTEGSEI-----TTASITG---SETTTASTEGSET 742
Query: 2329 STTLIE-----ILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSN 2383
+T E S TG+E T + T + A I S ++ S
Sbjct: 743 TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIG-SETTKVSTASSK 801
Query: 2384 KNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPSDLYYEPSGEGSGEVDIVDSFH 2443
+ E +ETT +ST A E T + S+ P+ E
Sbjct: 802 MTTVFTENSETTIASTT----------ASETTTVSTAGSETI--PASTAGSE-------- 841
Query: 2444 TSATTQATRQESSTTFVSDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSEQNKSSPDPT 2503
+ TT +T +TT ++GS E +A +++ ++ + + S T
Sbjct: 842 -TTTTTSTEGSETTTASTEGS-----ETTTASTESSETTTATTIGSETTTASTEGSETTT 895
Query: 2504 STLSNTVSYERSTDGSFQDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDLILTITESTI 2563
++ + + ST+GS E +T+ + T E + TE +
Sbjct: 896 TSTEGSETTTASTEGS--------EITTVSTTGSETT-----TASTEGSETTTASTEGSE 942
Query: 2564 LEILPELTSDKNTIIDIDHTKPVYEDILGMQTDIDTEVPSEPHDSNDESNDDSTQVQEIY 2623
L + T + + + ++ +G +T + SE + ++ +T E
Sbjct: 943 LTTV-STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGS 1001
Query: 2624 EAAVNLSLTEETFEGSADVLASYTQATHDESMTYEDRSQLDHMGFHFTTGIPAPSTETE 2682
E S ET S + +T T + + +TTG +T TE
Sbjct: 1002 ETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV-YTTGSETTTTSTE 1059
Score = 61.6 bits (148), Expect = 1e-08
Identities = 178/834 (21%), Positives = 275/834 (32%), Gaps = 120/834 (14%)
Query: 528 ESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVITVSKT-S 586
E+ T S + T G T+ D E ++ E T+ + E TVS T S
Sbjct: 622 ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 681
Query: 587 EDTIHTH--------LEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGK 638
E T+ T + E+ STT S GS + T+ IT G
Sbjct: 682 ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI-------TTASIT----GS 730
Query: 639 YLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRERTETLIPEMRTDT 698
+T EG T T T E T T T
Sbjct: 731 ETTTAS--------------------TEGSETT------TASTEGSETTSASTTGSETTT 764
Query: 699 YTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMTKSFDFPTLITKLSA 758
E T + MG ST SE V+ +S +MT F + T S
Sbjct: 765 -ASTTSSETTMASIMGS------ETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817
Query: 759 EPTEVRDMEEDFTAT-PGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPLES 817
+E + + T P +T E TT S E + + S + TT+ ES
Sbjct: 818 TASETTTVSTAGSETIPASTAGSETTTTT-------STEGSETTTASTEGSETTTASTES 870
Query: 818 TEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDED---IA 874
+E + ++ + + TT G + S +G++ T + ++ T + +
Sbjct: 871 SETTTATTI-GSETTTASTEGSETTTTS--TEGSETTTASTEGSEITTVSTTGSETTTAS 927
Query: 875 AHGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLS 934
G T T ST +E +T+ + +E +E TM +
Sbjct: 928 TEGSET----TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSET 983
Query: 935 KPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWG---------- 984
VST T+ +EG + SST TT V ++ T + I T+
Sbjct: 984 TTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT--ETTITSTEGSETTTVTTAGS 1041
Query: 985 --VLVPSVPSEDEVLGEPSQDILVIDQTRLE-ATISPETMRTTKIT---EGTTQEEFPWK 1038
V + SE + + T E T S + TT ++ GTT
Sbjct: 1042 ETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGS 1101
Query: 1039 EQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKI 1098
E T + ++TA T T + + + + + E+ T V ETT V I
Sbjct: 1102 ETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT--VFTTVSETTTVSTI 1159
Query: 1099 DHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFS 1158
+ A +E + E T S + T GS TT ++S S +
Sbjct: 1160 GSEATTSSAAGSEATTTSTEGSETT-----TASTAGSETTTASTAGSETTTASTSGSETN 1214
Query: 1159 THITQLMEETTTEKTSLE---------DIDLGSGLFEKPKATELIEFSTIKVTVPSDITT 1209
T T E +T E + + S +P AT L T V++ + T
Sbjct: 1215 TACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITASGAT 1274
Query: 1210 AFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAK 1269
A +S TT ++ ++ +P G TT + S + P A
Sbjct: 1275 A-ASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAAS 1333
Query: 1270 ETETDI--DREYFTTSSPPA------------TQPTRPPTVEDKEAFGPQALST 1309
T I + TS+ A T TR PT + GP ++ T
Sbjct: 1334 HTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGT 1387
>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1612
Score = 124 bits (310), Expect = 2e-27
Identities = 303/1401 (21%), Positives = 479/1401 (34%), Gaps = 98/1401 (6%)
Query: 1093 TPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPR-IGPKVSLSPGPEQKYETEGSSTTGFT 1151
+P G VS +T E T++ G + G E T GS TT
Sbjct: 49 SPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT-V 107
Query: 1152 SSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDITTAF 1211
S +T ++ + ETTT T+ + + S + + T TTA
Sbjct: 108 SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAA 167
Query: 1212 SSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKET 1271
S+ TT S IT G ETT+ + G T+ V T E A
Sbjct: 168 STTGSEMTTVFTAGSETITPSTA------GSETTT-VSTAGSETTTVSTTGSETTTASTA 220
Query: 1272 ETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRE 1331
++ S T A ST +T F D
Sbjct: 221 HSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTG 280
Query: 1332 NKTGRMSDLS---VIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEE 1388
+T S + + SE+ ET V +E+ F E +
Sbjct: 281 FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET--IRAST 338
Query: 1389 NEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSE 1448
E + TTT S+ G T E A E+ S ++ SE
Sbjct: 339 VGSETTTVSTTGSETTTASIM---GSETSTDSTTGSETTTASTEGSETTTAS---TEGSE 392
Query: 1449 SDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHE 1508
+ T ++T + +T TE E+T T ET+ + G + E
Sbjct: 393 ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452
Query: 1509 EFESGTAKKGAESVTER--DTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARAT 1566
+ T +VT +T+ + T S E++ I ++ A +
Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-ASTEGS 511
Query: 1567 EVTFGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQ 1626
E T + T ++ S SE V+ G L T + E +
Sbjct: 512 ETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG-------LETTTTSTEGSEMT 564
Query: 1627 VVELSGS-SSIPITEGSGE-AEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEV 1684
V +G+ ++ TEGSG A + T V+ NTT + +T+ T
Sbjct: 565 TVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETT 624
Query: 1685 PATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEG---TTGTASTFEVY 1741
A+T + S + T VS TD+ + STT E+ EG TT +A+ E
Sbjct: 625 TASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684
Query: 1742 SSTQRSDQLILPFE-LESPNVATSSDSGTRKSF--MSLTTPTQSEREMTDSTPVFTETNT 1798
ST+ S + E+ V+T+ T S +TT + + E T ++ +ET T
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT 744
Query: 1799 LENLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFS--LNV 1856
G++TT S+ T+ + AS+ + + + ETT VS+ S +
Sbjct: 745 ASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT 804
Query: 1857 EYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPN 1916
+ +E +A T + T + + ST T+ S S E
Sbjct: 805 VFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETT 864
Query: 1917 YGA-EIRGFSTGFPLEED---FSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPS 1972
+ E +T + + S + E +T S ++ T EGS T + +
Sbjct: 865 TASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETT 924
Query: 1973 TVPTSVHISHISDSEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQK 2032
T T + + +EG T VST+ E T SAEGS VT S
Sbjct: 925 TASTEGSETTTASTEGSELTTVSTTGS--ETITVSAEGSETTTVTTMGSETTT------- 975
Query: 2033 FSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQTI 2092
+ TA S E TV+ +T TA +EG++ + TVST +T
Sbjct: 976 -ASTAGS-------ETTTVSTAGSETT---TASIEGSETTTVSSTGSETTTVSTTGTETT 1024
Query: 2093 EPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTET--EL 2150
+ S E V SETT+ E + S + S T + S+T T + +L
Sbjct: 1025 ITSTEGS--ETTTV-TTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL 1081
Query: 2151 KTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATE-KSHFFLAT 2209
+TT S + T + + + T G E+ T ++E + +
Sbjct: 1082 ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGS 1141
Query: 2210 ALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTE-LLFSGLGSGEEVLPTLPT 2268
+ T T S I E +T T +E S GS T +
Sbjct: 1142 EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGS 1201
Query: 2269 ESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFE-GSGSV 2327
E+ + NT S+ + SS E N A +G S+T I S
Sbjct: 1202 ETTTASTSGSETNTACTTGSETSTPSSAGSE-----TNTAFIIG---SETTIASTASLEP 1253
Query: 2328 TSTTLIEILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSNKNSS 2387
T+T+L TG+E TV+ + + TV + T + +N S
Sbjct: 1254 TATSL------TGSETTTVS---ITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1304
Query: 2388 TAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPS--DLYYEPSGEGS---GEVDIVDSF 2442
T +++ + A G +F SA + + SG G+ G +
Sbjct: 1305 GTRTTGTRPTASSSVTMAPGM----DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAH 1360
Query: 2443 HTSATTQATRQESSTTFVSDG 2463
TT +TR+ +S+TF G
Sbjct: 1361 GVRTTTGSTREPTSSTFQETG 1381
Score = 102 bits (254), Expect = 6e-21
Identities = 328/1527 (21%), Positives = 521/1527 (34%), Gaps = 225/1527 (14%)
Query: 566 SDESTLIFDQIPEVITVSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEER 625
S E+T+ T S T +T ++ E+ +AST S P GS
Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGS-------- 53
Query: 626 QTSGRITEEFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRE 685
QT+ G ++TT T + + G T + + T
Sbjct: 54 QTT---IVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSIT 110
Query: 686 RTE-TLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMT 744
TE T++ M ++T T+ T ST+ SE V+ E T
Sbjct: 111 GTETTMVSAMGSETTTNSTTSSET---------------TVTSTAGSETTTVSTVGSETT 155
Query: 745 KSFDFPTLITKLSAEPTEVRDMEEDFTA-----TPGTTKYDENITTVLLAHGTLSVEAAT 799
++ T ++ +A T +M FTA TP T TTV A + + T
Sbjct: 156 TAY---TADSETTAASTTGSEMTTVFTAGSETITPSTA--GSETTTVSTAGSETTTVSTT 210
Query: 800 VSKWSWDEDNTTSKPLESTEPSASSKLPPA-LLTTVGMNGKDKDIPSFTEDGADEFTLIP 858
S+ + + ST S ++K+ A TTV G + S TED
Sbjct: 211 GSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAAS-TEDSETNTAFTE 269
Query: 859 DSTQKQLEEVTDEDIAAHGKFTIRFQPTTSTGIAEKSTLRDSTTEE--KVPPITSTEGQV 916
DS E AA T +PT ++ + ++T+ + E KV +S V
Sbjct: 270 DSKTTTASTTGFETTAAS---TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV 326
Query: 917 YA----TMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHT 972
+A T+ S +G + VST T+ + G + S+T TT +
Sbjct: 327 FAAGSETIRASTVGSE-----TTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTE-- 379
Query: 973 IPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEATI--SPETMRTTKITEGT 1030
SE + + T E T ++ TT TEG+
Sbjct: 380 ------------------GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGS 421
Query: 1031 TQEEFPWKEQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVL 1090
E TA ++TA T +T + S+ E T S
Sbjct: 422 --------EMTAVSTTVFETTTASTEGSEIT----------IASTSDSETTTASTEGSET 463
Query: 1091 ETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGF 1150
T + +Y G+ T T T IG + + TEGS TT
Sbjct: 464 TTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA-------STEGSETTAV 516
Query: 1151 TSSLSPFSTHITQLMEETTTEKTSLEDIDLG-SGLFEKPKATELIEFSTIKVTVPSDITT 1209
+++ S +T T+ E TT T E + +GL +TE E +T+ T T
Sbjct: 517 SATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT---GAET 573
Query: 1210 AFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAK 1269
S + TT+A S T D E +T+D ST+ TT ++
Sbjct: 574 TTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632
Query: 1270 ETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEV 1329
T + TT S ++ T T + S ++T ++
Sbjct: 633 TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS------ 686
Query: 1330 RENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEEN 1389
+ + +S+ G SE+ + ET +EI E +E +
Sbjct: 687 --TEGSGTTTVSITG----SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740
Query: 1390 EEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSES 1449
E TTT S + G + E A E+ S S+++ +
Sbjct: 741 E------------TTTASTE---GSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785
Query: 1450 DTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEE 1509
T + ++T + +T TE+ E T T ET+ + G + P E
Sbjct: 786 ST---IGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS-ETIPASTAGSE 841
Query: 1510 FESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVT 1569
+ T+ +G+E+ T TE TE E++ I E+ T T
Sbjct: 842 TTTTTSTEGSETTT-ASTEGSETTTASTE-----SSETTTATTIGSET-------TTAST 888
Query: 1570 FGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPW---PDDLLSTKESWVEATPRQ 1626
G E T+ T T ++AS SE V+ G+ + T + E +
Sbjct: 889 EGSE----TTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELT 944
Query: 1627 VVELSGSSSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEVPA 1686
V +GS +I ++ G TM + T S + T ++ S T S
Sbjct: 945 TVSTTGSETITVS-AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET 1003
Query: 1687 TTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQR 1746
TT+ + T VS T T I+ST E TT + T VY++
Sbjct: 1004 TTVSSTGSE-------TTTVSTTGTETTITSTEGSETTTV----TTAGSETTAVYTT--- 1049
Query: 1747 SDQLILPFELESPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTETNTLENLGAQT 1806
T+S G+ TT + + E T ++ ET T+ G+ T
Sbjct: 1050 -----------GSETTTTSTEGS-----ETTTVSTTGSETTTASTADLETTTVSTSGSGT 1093
Query: 1807 TEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEV 1866
T S+ G + + S + +GS E TTVS+ S +E
Sbjct: 1094 TTAST---AGSETTTVYITGSKTTTASTEGS-------EATTVSTTS--------SETTT 1135
Query: 1867 AGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFST 1926
A T + T F+T +ST+ T+ SE G+E ST
Sbjct: 1136 ASTTGSEMTTVFTTVSETTTVSTIGSEA-------TTSSAAGSEATTTSTEGSETTTAST 1188
Query: 1927 GFPLEEDFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVPTSVHISHISDS 1986
S E +T S ++ T GS +T T PS+ + + + I S
Sbjct: 1189 AGSETTTASTAGSETTTASTSGSETNTACTTGS------ETST-PSSAGSETNTAFIIGS 1241
Query: 1987 EGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQKFSGTASSIIDEGLG 2046
E +T+ ST++ E +S GS V++++S + V + + D +
Sbjct: 1242 E---TTIASTASL--EPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQ 1296
Query: 2047 EVGTVNEIDRRST-ILPTAEVEGTKAP 2072
+ R+T PTA T AP
Sbjct: 1297 PITNTPMSGTRTTGTRPTASSSVTMAP 1323
Score = 100 bits (250), Expect = 2e-20
Identities = 295/1437 (20%), Positives = 482/1437 (33%), Gaps = 128/1437 (8%)
Query: 678 TEMTHRRERTETLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKL---STSLSEPI 734
T T E T LI T T + E T SP +T SG ++ ST+ SE
Sbjct: 17 TASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENT 76
Query: 735 HVTE------------SSVEMTKSFDFPTLITKLSAEPTEVRDMEEDFTATPGTTKYDEN 782
V+ S ++ + T ++ E T V M + T T TT +
Sbjct: 77 TVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSE-TTTNSTTSSETT 135
Query: 783 ITTVLLAHGTL--SVEAATVSKWSWDED----NTTSKPLESTEPSASSKLPPALL----- 831
+T+ + T +V + T + ++ D + +TT + + + S + P+
Sbjct: 136 VTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 195
Query: 832 ---------TTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDEDIAAHGKFTIR 882
TTV G + S + + T K ++ ++ G
Sbjct: 196 TVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS---- 251
Query: 883 FQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSKPVSTVPQ 942
T+ E S + TE+ ST G + T S G + ++ + +
Sbjct: 252 ---ETTAASTEDSETNTAFTEDSKTTTASTTG--FETTAASTTGS--EPTMASTMGSETT 304
Query: 943 FAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVI-PKTDWGVLVPSVPSEDEVLG-EP 1000
A T E VS +S++ T + S TI S + +T S + ++G E
Sbjct: 305 MASTIGPETTK-VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET 363
Query: 1001 SQDILVIDQTRLEATISPETMRTTKITEGT--TQEEFPWKEQTAEKPVPALSSTAWTPKE 1058
S D +T +T ET TT TEG+ T E T + ++T T
Sbjct: 364 STDSTTGSETTTASTEGSET--TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGS 421
Query: 1059 AVTPLDEQ-------EGDGSAYTV---SEDELLTGSERVPVLETTPVGKIDHSVSYPPGA 1108
+T + +GS T+ S+ E T S T + +Y G+
Sbjct: 422 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 481
Query: 1109 VTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEET 1168
T T T IG + + TEGS TT +++ S +T T+ E T
Sbjct: 482 ETTTASNTGLETTTVFTIGSDTTTA-------STEGSETTAVSATGSEMTTVSTEGSENT 534
Query: 1169 TTEKTSLEDIDLGS-GLFEKPKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSS 1227
T T E + + GL +TE E +T+ T T S + TT+A S
Sbjct: 535 TVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT---GAETTTDSTEGSGTTAASTAGS 591
Query: 1228 AITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKETETDIDREYFTTSSPPA 1287
T D E +T+D ST+ TT ++ T + TT S
Sbjct: 592 ETTTVSTA-DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650
Query: 1288 TQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVY-----IIEVRENKTGRMSDLSV 1342
++ T T + S ++T ++ + + ++T ++S
Sbjct: 651 SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGS 710
Query: 1343 IGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDV 1402
+E E S E E S E A+ T
Sbjct: 711 ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSS 770
Query: 1403 TTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQN---FSDSSESDTHPFVIAKT 1459
TT + + + +T+ + + +V + + ++ S+T A +
Sbjct: 771 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS 830
Query: 1460 ELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGA 1519
E A T TT S E + E SE + T E+ TA
Sbjct: 831 ETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEG 890
Query: 1520 ESVTERDTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTS 1579
T TE TE + ++G ++ T T G E+ + S
Sbjct: 891 SETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTE--GSETTTASTEGSELT-TVS 947
Query: 1580 VTYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPIT 1639
T + TI + SA SE VT +G+ T + + V +GS + T
Sbjct: 948 TTGSETI---TVSAEGSETTTVTTMGS-------ETTTASTAGSETTTVSTAGSET---T 994
Query: 1640 EGSGEAEEDEDTMFT--MVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIYPVSEQPS 1697
S E E T T +S T T+ + + S T + T +Y + +
Sbjct: 995 TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT 1054
Query: 1698 AKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELE 1757
SET T S T E T T+ + +ST S+ + +
Sbjct: 1055 TTSTEG---SETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTV--YIT 1109
Query: 1758 SPNVATSSDSGTRKSFMSLTTPTQSEREMTDS--TPVFT---ETNTLENLGAQTTEHSSI 1812
T+S G+ + +S T+ + T S T VFT ET T+ +G++ T S+
Sbjct: 1110 GSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169
Query: 1813 HQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSS--FSLNVEYAIQAEKEVAGTL 1870
+ AS + + + A ETTT S+ N +E +
Sbjct: 1170 GSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSA 1229
Query: 1871 SPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPL 1930
T F + ST A ++T + V G A ST F L
Sbjct: 1230 GSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGAT--AASTTVSSTTFVL 1287
Query: 1931 EEDFSGDFREY---------STVSHPIAKEETVMMEGSGDAAFRDTQTSPSTV--PTSVH 1979
+ + +T + P A M G A + T P V + +
Sbjct: 1288 TKATDVSIQPITNTPMSGTRTTGTRPTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLG 1347
Query: 1980 ISHISDSEGPSSTMVSTSAFPWEEFTSSA-EGSGEQLVTVSSSVVPVLPSAVQKFSG 2035
S + S S+ V T+ E TSS + +G + ++ + P+ V K SG
Sbjct: 1348 TSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPSG 1404
Score = 100 bits (250), Expect = 2e-20
Identities = 279/1377 (20%), Positives = 460/1377 (33%), Gaps = 164/1377 (11%)
Query: 522 TARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVIT 581
TA M T S + + TG + E T + S E+T+ E T
Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146
Query: 582 VSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGKYLS 641
VS +T + D E+ +ASTT S + GS IT G +
Sbjct: 147 VSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSE-----------TITPSTAGSETT 195
Query: 642 TTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTH-RRERTETLIPEMRTDTYT 700
T T + T ++ +E T +ET + ++T
Sbjct: 196 TVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTA 255
Query: 701 DEIQEEITKSPFM--GKTEEEVFSGMK---LSTSLSEPIHVTESSVEMTKSFDFPTLITK 755
++ T + F KT +G + ST+ SEP + E T + TK
Sbjct: 256 ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315
Query: 756 LSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPL 815
+S +EV + + T + TTV + + S+ S D +
Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 375
Query: 816 ESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDEDIAA 875
STE S + TT G + S T ++ T E ++ +
Sbjct: 376 ASTEGSET--------TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVS 427
Query: 876 HGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSK 935
T F+ TT++ E S + ++T + STEG T+ + +K
Sbjct: 428 ----TTVFETTTAS--TEGSEITIASTSDSETTTASTEGSETTTVTTAG-------SETK 474
Query: 936 PVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDE 995
T T+ GL + + TT + + +V V + SE+
Sbjct: 475 TAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENT 534
Query: 996 VLGEPSQDILVIDQTRLEATISPETMRTTKITEGT--TQEEFPWKEQTAEKPVPALSSTA 1053
+ + + T LE TT TEG+ T E T + + ++ A
Sbjct: 535 TVSTTGSETTTVSTTGLET--------TTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA 586
Query: 1054 WTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHK 1113
T T + + + + + ++ E + S T + + + G+ T
Sbjct: 587 STAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTV 646
Query: 1114 VKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKT 1173
TD T+ G + +++ TEGS TT +++ S +T T+ TT T
Sbjct: 647 STTDSETTMVSTTGSERTIT-------STEGSETTTVSATGSE-TTVSTEGSGTTTVSIT 698
Query: 1174 SLEDIDLG-SGLFEKPKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKK 1232
E + +G +TE E +T +T S+ TTA S + TT+A S T
Sbjct: 699 GSETTKVSTTGSETTTTSTEGSEITTASIT-GSETTTA--STEGSETTTASTEGSETTSA 755
Query: 1233 PPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTR 1292
G ETT+ E TT+ I+ ET T +S ++ T+
Sbjct: 756 -----STTGSETTTASTTSSE-------TTMASIMGSET---------TMASTIGSETTK 794
Query: 1293 PPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESK 1352
+ST +T F + I ++T +S
Sbjct: 795 --------------VSTASSKMTTVFTENSETTIASTTASETTTVS-------------- 826
Query: 1353 EDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYIN 1412
ET P +E S E E +++ TT ++
Sbjct: 827 ---TAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI---- 879
Query: 1413 GKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTE 1472
G T E +E E + ++ SE T ++T ++ +T
Sbjct: 880 GSETTTA---STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTA 936
Query: 1473 TTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQ 1532
+TE E+T T ET + G T E + TA +V+ +E
Sbjct: 937 STEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTA 996
Query: 1533 AHEHTEPVSLFPEES-SGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSA 1591
+ E +E ++ S + ++ I +E T T+ YT ++
Sbjct: 997 SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTT 1056
Query: 1592 SAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDT 1651
S SE V+ G+ + + + +E T V SGS T + A + T
Sbjct: 1057 STEGSETTTVSTTGS----ETTTASTADLETT---TVSTSGSG----TTTASTAGSETTT 1105
Query: 1652 MF---TMVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKFVSE 1708
++ + T S + T ++ +S T S TT++ VSE
Sbjct: 1106 VYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT-------------VSE 1152
Query: 1709 TDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELESPNVATSSDSG 1768
T T I S E TT T + +ST S E+ +T+
Sbjct: 1153 TTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS---------ETTTASTAGSET 1203
Query: 1769 TRKSFMSLTTPTQSEREMTDSTP--VFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLPR 1826
T S T T STP +ETNT +G++TT S+ ++ T+L
Sbjct: 1204 TTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAST---ASLEPTATSLTG 1260
Query: 1827 SPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEVAGTLSPHVETTFSTEPT 1883
S + SG AA +TTVSS + + A + T T PT
Sbjct: 1261 SETTTVSITASGATAA---STTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRPT 1314
Score = 87.4 bits (215), Expect = 2e-16
Identities = 253/1199 (21%), Positives = 427/1199 (35%), Gaps = 185/1199 (15%)
Query: 1526 DTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPT 1585
+T V A +T S E++ + E+ + A + T ++T V+ + +
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 1586 IVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQV--VELSGSSSIPITEGSG 1643
+ ++++A SE V+ G+ ++ E+ V + V ++G+ + ++
Sbjct: 64 EITTTSTAG-SENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122
Query: 1644 EAEEDEDTMF--TMVTDLSQRNTTDTLITLDTSRIITESFFEVPATT----IYPVSEQPS 1697
E + T T+ + TT + + +T+ T A+T + V S
Sbjct: 123 ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGS 182
Query: 1698 AKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELE 1757
+ P+ SET T S T E T TA + +ST S E
Sbjct: 183 ETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGS---------E 233
Query: 1758 SPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTE---TNTLENLGAQTTEHSSIHQ 1814
+ V+T+ T + S TT +E T++ FTE T T G +TT S+
Sbjct: 234 TTKVSTAGSETTVSTAGSETTAASTEDSETNTA--FTEDSKTTTASTTGFETTAAST--- 288
Query: 1815 PGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEV--AGTLSP 1872
T + AS + + + PETT VS+ S V A E A T+
Sbjct: 289 -------TGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS 341
Query: 1873 HVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPLEE 1932
TT ST + +++M + + T S S G+E ST
Sbjct: 342 ET-TTVSTTGSETTTASIMGSETSTDSTTGSETTTASTE------GSETTTASTEGSEAT 394
Query: 1933 DFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDT---QTSPSTVPTSVHISHISDSE-- 1987
S E +TVS ++ T EGS A T T+ ST + + I+ SDSE
Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454
Query: 1988 -----GPSSTMVSTS------AFPWEEFTSSAEGSGEQLVTV--------SSSVVPVLPS 2028
G +T V+T+ A+ T++A +G + TV ++S +
Sbjct: 455 TASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514
Query: 2029 AVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNF 2088
AV +++ EG E TV+ +T + T +E T E E+ TVST
Sbjct: 515 AVSATGSEMTTVSTEG-SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMT---TVSTTG 570
Query: 2089 PQTIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTET 2148
+T + S TT+ E + S +S T + DS+T T
Sbjct: 571 AETTTDSTEGSG-------------TTAASTAGSETTTVSTADSENTTASTADSET---T 614
Query: 2149 ELKTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATEKSHFFLA 2208
TT T T S+ E + +ST D S TT+ T
Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTD-------SETTMVSTTG------- 660
Query: 2209 TALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLPT 2268
+E +T + + E+T T+ + +E S GSG T
Sbjct: 661 ---------SERTITST--EGSETT---------TVSATGSETTVSTEGSGTT------T 694
Query: 2269 ESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVT 2328
S+ +E +++ T S+ +TS++ E A G S+T GS T
Sbjct: 695 VSITGSETTKVSTT----GSETTTTSTEGSEI-----TTASITG---SETTTASTEGSET 742
Query: 2329 STTLIE-----ILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSN 2383
+T E S TG+E T + T + A I S ++ S
Sbjct: 743 TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIG-SETTKVSTASSK 801
Query: 2384 KNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPSDLYYEPSGEGSGEVDIVDSFH 2443
+ E +ETT +ST A E T + S+ P+ E
Sbjct: 802 MTTVFTENSETTIASTT----------ASETTTVSTAGSETI--PASTAGSE-------- 841
Query: 2444 TSATTQATRQESSTTFVSDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSEQNKSSPDPT 2503
+ TT +T +TT ++GS E +A +++ ++ + + S T
Sbjct: 842 -TTTTTSTEGSETTTASTEGS-----ETTTASTESSETTTATTIGSETTTASTEGSETTT 895
Query: 2504 STLSNTVSYERSTDGSFQDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDLILTITESTI 2563
++ + + ST+GS E +T+ + T E + TE +
Sbjct: 896 TSTEGSETTTASTEGS--------EITTVSTTGSETT-----TASTEGSETTTASTEGSE 942
Query: 2564 LEILPELTSDKNTIIDIDHTKPVYEDILGMQTDIDTEVPSEPHDSNDESNDDSTQVQEIY 2623
L + T + + + ++ +G +T + SE + ++ +T E
Sbjct: 943 LTTV-STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGS 1001
Query: 2624 EAAVNLSLTEETFEGSADVLASYTQATHDESMTYEDRSQLDHMGFHFTTGIPAPSTETE 2682
E S ET S + +T T + + +TTG +T TE
Sbjct: 1002 ETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV-YTTGSETTTTSTE 1059
Score = 60.8 bits (146), Expect = 2e-08
Identities = 181/835 (21%), Positives = 275/835 (32%), Gaps = 122/835 (14%)
Query: 528 ESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVITVSKT-S 586
E+ T S + T G T+ D E ++ E T+ + E TVS T S
Sbjct: 622 ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 681
Query: 587 EDTIHTH--------LEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGK 638
E T+ T + E+ STT S GS + T+ IT G
Sbjct: 682 ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI-------TTASIT----GS 730
Query: 639 YLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRERTETLIPEMRTDT 698
+T EG T T T E T T T
Sbjct: 731 ETTTAS--------------------TEGSETT------TASTEGSETTSASTTGSETTT 764
Query: 699 YTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMTKSFDFPTLITKLSA 758
E T + MG ST SE V+ +S +MT F + T S
Sbjct: 765 -ASTTSSETTMASIMGS------ETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817
Query: 759 EPTEVRDMEEDFTAT-PGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPLES 817
+E + + T P +T E TT S E + + S + TT+ ES
Sbjct: 818 TASETTTVSTAGSETIPASTAGSETTTTT-------STEGSETTTASTEGSETTTASTES 870
Query: 818 TEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDED---IA 874
+E + ++ + + TT G + S +G++ T + ++ T + +
Sbjct: 871 SETTTATTI-GSETTTASTEGSETTTTS--TEGSETTTASTEGSEITTVSTTGSETTTAS 927
Query: 875 AHGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLS 934
G T T ST +E +T+ + +E +E TM +
Sbjct: 928 TEGSET----TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSET 983
Query: 935 KPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWG---------- 984
VST T+ +EG + SST TT V ++ T + I T+
Sbjct: 984 TTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT--ETTITSTEGSETTTVTTAGS 1041
Query: 985 --VLVPSVPSEDEVLGEPSQDILVIDQTRLE-ATISPETMRTTKIT---EGTTQEEFPWK 1038
V + SE + + T E T S + TT ++ GTT
Sbjct: 1042 ETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGS 1101
Query: 1039 EQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKI 1098
E T + ++TA T T + + + + + E+ T V ETT V I
Sbjct: 1102 ETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT--VFTTVSETTTVSTI 1159
Query: 1099 DHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFS 1158
+ A +E + E T S + T GS TT ++S S +
Sbjct: 1160 GSEATTSSAAGSEATTTSTEGSETT-----TASTAGSETTTASTAGSETTTASTSGSETN 1214
Query: 1159 THITQLMEETTTEKTSLE---------DIDLGSGLFEKPKATELIEFSTIKVTVPSDITT 1209
T T E +T E + + S +P AT L T V++ + T
Sbjct: 1215 TACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGAT 1274
Query: 1210 AFSSVDRLHTTSAFKPSSA----ITKKPPLIDREPGEETTSD--------MVIIGESTSH 1257
A S+ T K + IT P R G T+ M + SH
Sbjct: 1275 AASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRPTASSSVTMAPGMDFTASAASH 1334
Query: 1258 VPPTTLEDIVAKETETDIDREYFTTSS---PPATQPTRPPTVEDKEAFGPQALST 1309
P + + T T TTS+ T TR PT + GP ++ T
Sbjct: 1335 TVPGIVLNTSGLGTST--MGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGT 1387
>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1704
Score = 124 bits (310), Expect = 2e-27
Identities = 303/1401 (21%), Positives = 479/1401 (34%), Gaps = 98/1401 (6%)
Query: 1093 TPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPR-IGPKVSLSPGPEQKYETEGSSTTGFT 1151
+P G VS +T E T++ G + G E T GS TT
Sbjct: 49 SPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT-V 107
Query: 1152 SSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDITTAF 1211
S +T ++ + ETTT T+ + + S + + T TTA
Sbjct: 108 SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAA 167
Query: 1212 SSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKET 1271
S+ TT S IT G ETT+ + G T+ V T E A
Sbjct: 168 STTGSEMTTVFTAGSETITPSTA------GSETTT-VSTAGSETTTVSTTGSETTTASTA 220
Query: 1272 ETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRE 1331
++ S T A ST +T F D
Sbjct: 221 HSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTG 280
Query: 1332 NKTGRMSDLS---VIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEE 1388
+T S + + SE+ ET V +E+ F E +
Sbjct: 281 FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET--IRAST 338
Query: 1389 NEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSE 1448
E + TTT S+ G T E A E+ S ++ SE
Sbjct: 339 VGSETTTVSTTGSETTTASIM---GSETSTDSTTGSETTTASTEGSETTTAS---TEGSE 392
Query: 1449 SDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHE 1508
+ T ++T + +T TE E+T T ET+ + G + E
Sbjct: 393 ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452
Query: 1509 EFESGTAKKGAESVTER--DTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARAT 1566
+ T +VT +T+ + T S E++ I ++ A +
Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-ASTEGS 511
Query: 1567 EVTFGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQ 1626
E T + T ++ S SE V+ G L T + E +
Sbjct: 512 ETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG-------LETTTTSTEGSEMT 564
Query: 1627 VVELSGS-SSIPITEGSGE-AEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEV 1684
V +G+ ++ TEGSG A + T V+ NTT + +T+ T
Sbjct: 565 TVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETT 624
Query: 1685 PATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEG---TTGTASTFEVY 1741
A+T + S + T VS TD+ + STT E+ EG TT +A+ E
Sbjct: 625 TASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684
Query: 1742 SSTQRSDQLILPFE-LESPNVATSSDSGTRKSF--MSLTTPTQSEREMTDSTPVFTETNT 1798
ST+ S + E+ V+T+ T S +TT + + E T ++ +ET T
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT 744
Query: 1799 LENLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFS--LNV 1856
G++TT S+ T+ + AS+ + + + ETT VS+ S +
Sbjct: 745 ASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT 804
Query: 1857 EYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPN 1916
+ +E +A T + T + + ST T+ S S E
Sbjct: 805 VFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETT 864
Query: 1917 YGA-EIRGFSTGFPLEED---FSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPS 1972
+ E +T + + S + E +T S ++ T EGS T + +
Sbjct: 865 TASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETT 924
Query: 1973 TVPTSVHISHISDSEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQK 2032
T T + + +EG T VST+ E T SAEGS VT S
Sbjct: 925 TASTEGSETTTASTEGSELTTVSTTGS--ETITVSAEGSETTTVTTMGSETTT------- 975
Query: 2033 FSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQTI 2092
+ TA S E TV+ +T TA +EG++ + TVST +T
Sbjct: 976 -ASTAGS-------ETTTVSTAGSETT---TASIEGSETTTVSSTGSETTTVSTTGTETT 1024
Query: 2093 EPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTET--EL 2150
+ S E V SETT+ E + S + S T + S+T T + +L
Sbjct: 1025 ITSTEGS--ETTTV-TTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL 1081
Query: 2151 KTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATE-KSHFFLAT 2209
+TT S + T + + + T G E+ T ++E + +
Sbjct: 1082 ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGS 1141
Query: 2210 ALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTE-LLFSGLGSGEEVLPTLPT 2268
+ T T S I E +T T +E S GS T +
Sbjct: 1142 EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGS 1201
Query: 2269 ESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFE-GSGSV 2327
E+ + NT S+ + SS E N A +G S+T I S
Sbjct: 1202 ETTTASTSGSETNTACTTGSETSTPSSAGSE-----TNTAFIIG---SETTIASTASLEP 1253
Query: 2328 TSTTLIEILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSNKNSS 2387
T+T+L TG+E TV+ + + TV + T + +N S
Sbjct: 1254 TATSL------TGSETTTVS---ITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMS 1304
Query: 2388 TAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPS--DLYYEPSGEGS---GEVDIVDSF 2442
T +++ + A G +F SA + + SG G+ G +
Sbjct: 1305 GTRTTGTRPTASSSVTMAPGM----DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAH 1360
Query: 2443 HTSATTQATRQESSTTFVSDG 2463
TT +TR+ +S+TF G
Sbjct: 1361 GVRTTTGSTREPTSSTFQETG 1381
Score = 102 bits (254), Expect = 6e-21
Identities = 328/1527 (21%), Positives = 521/1527 (34%), Gaps = 225/1527 (14%)
Query: 566 SDESTLIFDQIPEVITVSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEER 625
S E+T+ T S T +T ++ E+ +AST S P GS
Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGS-------- 53
Query: 626 QTSGRITEEFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRE 685
QT+ G ++TT T + + G T + + T
Sbjct: 54 QTT---IVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSIT 110
Query: 686 RTE-TLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMT 744
TE T++ M ++T T+ T ST+ SE V+ E T
Sbjct: 111 GTETTMVSAMGSETTTNSTTSSET---------------TVTSTAGSETTTVSTVGSETT 155
Query: 745 KSFDFPTLITKLSAEPTEVRDMEEDFTA-----TPGTTKYDENITTVLLAHGTLSVEAAT 799
++ T ++ +A T +M FTA TP T TTV A + + T
Sbjct: 156 TAY---TADSETTAASTTGSEMTTVFTAGSETITPSTA--GSETTTVSTAGSETTTVSTT 210
Query: 800 VSKWSWDEDNTTSKPLESTEPSASSKLPPA-LLTTVGMNGKDKDIPSFTEDGADEFTLIP 858
S+ + + ST S ++K+ A TTV G + S TED
Sbjct: 211 GSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAAS-TEDSETNTAFTE 269
Query: 859 DSTQKQLEEVTDEDIAAHGKFTIRFQPTTSTGIAEKSTLRDSTTEE--KVPPITSTEGQV 916
DS E AA T +PT ++ + ++T+ + E KV +S V
Sbjct: 270 DSKTTTASTTGFETTAAS---TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV 326
Query: 917 YA----TMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHT 972
+A T+ S +G + VST T+ + G + S+T TT +
Sbjct: 327 FAAGSETIRASTVGSE-----TTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTE-- 379
Query: 973 IPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEATI--SPETMRTTKITEGT 1030
SE + + T E T ++ TT TEG+
Sbjct: 380 ------------------GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGS 421
Query: 1031 TQEEFPWKEQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVL 1090
E TA ++TA T +T + S+ E T S
Sbjct: 422 --------EMTAVSTTVFETTTASTEGSEIT----------IASTSDSETTTASTEGSET 463
Query: 1091 ETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGF 1150
T + +Y G+ T T T IG + + TEGS TT
Sbjct: 464 TTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA-------STEGSETTAV 516
Query: 1151 TSSLSPFSTHITQLMEETTTEKTSLEDIDLG-SGLFEKPKATELIEFSTIKVTVPSDITT 1209
+++ S +T T+ E TT T E + +GL +TE E +T+ T T
Sbjct: 517 SATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT---GAET 573
Query: 1210 AFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAK 1269
S + TT+A S T D E +T+D ST+ TT ++
Sbjct: 574 TTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632
Query: 1270 ETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEV 1329
T + TT S ++ T T + S ++T ++
Sbjct: 633 TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS------ 686
Query: 1330 RENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEEN 1389
+ + +S+ G SE+ + ET +EI E +E +
Sbjct: 687 --TEGSGTTTVSITG----SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740
Query: 1390 EEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSES 1449
E TTT S + G + E A E+ S S+++ +
Sbjct: 741 E------------TTTASTE---GSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785
Query: 1450 DTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEE 1509
T + ++T + +T TE+ E T T ET+ + G + P E
Sbjct: 786 ST---IGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS-ETIPASTAGSE 841
Query: 1510 FESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVT 1569
+ T+ +G+E+ T TE TE E++ I E+ T T
Sbjct: 842 TTTTTSTEGSETTT-ASTEGSETTTASTE-----SSETTTATTIGSET-------TTAST 888
Query: 1570 FGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPW---PDDLLSTKESWVEATPRQ 1626
G E T+ T T ++AS SE V+ G+ + T + E +
Sbjct: 889 EGSE----TTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELT 944
Query: 1627 VVELSGSSSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEVPA 1686
V +GS +I ++ G TM + T S + T ++ S T S
Sbjct: 945 TVSTTGSETITVS-AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET 1003
Query: 1687 TTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQR 1746
TT+ + T VS T T I+ST E TT + T VY++
Sbjct: 1004 TTVSSTGSE-------TTTVSTTGTETTITSTEGSETTTV----TTAGSETTAVYTT--- 1049
Query: 1747 SDQLILPFELESPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTETNTLENLGAQT 1806
T+S G+ TT + + E T ++ ET T+ G+ T
Sbjct: 1050 -----------GSETTTTSTEGS-----ETTTVSTTGSETTTASTADLETTTVSTSGSGT 1093
Query: 1807 TEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEV 1866
T S+ G + + S + +GS E TTVS+ S +E
Sbjct: 1094 TTAST---AGSETTTVYITGSKTTTASTEGS-------EATTVSTTS--------SETTT 1135
Query: 1867 AGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFST 1926
A T + T F+T +ST+ T+ SE G+E ST
Sbjct: 1136 ASTTGSEMTTVFTTVSETTTVSTIGSEA-------TTSSAAGSEATTTSTEGSETTTAST 1188
Query: 1927 GFPLEEDFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVPTSVHISHISDS 1986
S E +T S ++ T GS +T T PS+ + + + I S
Sbjct: 1189 AGSETTTASTAGSETTTASTSGSETNTACTTGS------ETST-PSSAGSETNTAFIIGS 1241
Query: 1987 EGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQKFSGTASSIIDEGLG 2046
E +T+ ST++ E +S GS V++++S + V + + D +
Sbjct: 1242 E---TTIASTASL--EPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQ 1296
Query: 2047 EVGTVNEIDRRST-ILPTAEVEGTKAP 2072
+ R+T PTA T AP
Sbjct: 1297 PITNTPMSGTRTTGTRPTASSSVTMAP 1323
Score = 100 bits (250), Expect = 2e-20
Identities = 295/1437 (20%), Positives = 482/1437 (33%), Gaps = 128/1437 (8%)
Query: 678 TEMTHRRERTETLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKL---STSLSEPI 734
T T E T LI T T + E T SP +T SG ++ ST+ SE
Sbjct: 17 TASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENT 76
Query: 735 HVTE------------SSVEMTKSFDFPTLITKLSAEPTEVRDMEEDFTATPGTTKYDEN 782
V+ S ++ + T ++ E T V M + T T TT +
Sbjct: 77 TVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSE-TTTNSTTSSETT 135
Query: 783 ITTVLLAHGTL--SVEAATVSKWSWDED----NTTSKPLESTEPSASSKLPPALL----- 831
+T+ + T +V + T + ++ D + +TT + + + S + P+
Sbjct: 136 VTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 195
Query: 832 ---------TTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDEDIAAHGKFTIR 882
TTV G + S + + T K ++ ++ G
Sbjct: 196 TVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS---- 251
Query: 883 FQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSKPVSTVPQ 942
T+ E S + TE+ ST G + T S G + ++ + +
Sbjct: 252 ---ETTAASTEDSETNTAFTEDSKTTTASTTG--FETTAASTTGS--EPTMASTMGSETT 304
Query: 943 FAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVI-PKTDWGVLVPSVPSEDEVLG-EP 1000
A T E VS +S++ T + S TI S + +T S + ++G E
Sbjct: 305 MASTIGPETTK-VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET 363
Query: 1001 SQDILVIDQTRLEATISPETMRTTKITEGT--TQEEFPWKEQTAEKPVPALSSTAWTPKE 1058
S D +T +T ET TT TEG+ T E T + ++T T
Sbjct: 364 STDSTTGSETTTASTEGSET--TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGS 421
Query: 1059 AVTPLDEQ-------EGDGSAYTV---SEDELLTGSERVPVLETTPVGKIDHSVSYPPGA 1108
+T + +GS T+ S+ E T S T + +Y G+
Sbjct: 422 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 481
Query: 1109 VTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEET 1168
T T T IG + + TEGS TT +++ S +T T+ E T
Sbjct: 482 ETTTASNTGLETTTVFTIGSDTTTA-------STEGSETTAVSATGSEMTTVSTEGSENT 534
Query: 1169 TTEKTSLEDIDLGS-GLFEKPKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSS 1227
T T E + + GL +TE E +T+ T T S + TT+A S
Sbjct: 535 TVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT---GAETTTDSTEGSGTTAASTAGS 591
Query: 1228 AITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKETETDIDREYFTTSSPPA 1287
T D E +T+D ST+ TT ++ T + TT S
Sbjct: 592 ETTTVSTA-DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650
Query: 1288 TQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVY-----IIEVRENKTGRMSDLSV 1342
++ T T + S ++T ++ + + ++T ++S
Sbjct: 651 SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGS 710
Query: 1343 IGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDV 1402
+E E S E E S E A+ T
Sbjct: 711 ETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSS 770
Query: 1403 TTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQN---FSDSSESDTHPFVIAKT 1459
TT + + + +T+ + + +V + + ++ S+T A +
Sbjct: 771 ETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS 830
Query: 1460 ELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGA 1519
E A T TT S E + E SE + T E+ TA
Sbjct: 831 ETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEG 890
Query: 1520 ESVTERDTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTS 1579
T TE TE + ++G ++ T T G E+ + S
Sbjct: 891 SETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTE--GSETTTASTEGSELT-TVS 947
Query: 1580 VTYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPIT 1639
T + TI + SA SE VT +G+ T + + V +GS + T
Sbjct: 948 TTGSETI---TVSAEGSETTTVTTMGS-------ETTTASTAGSETTTVSTAGSET---T 994
Query: 1640 EGSGEAEEDEDTMFT--MVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIYPVSEQPS 1697
S E E T T +S T T+ + + S T + T +Y + +
Sbjct: 995 TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETT 1054
Query: 1698 AKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELE 1757
SET T S T E T T+ + +ST S+ + +
Sbjct: 1055 TTSTEG---SETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTV--YIT 1109
Query: 1758 SPNVATSSDSGTRKSFMSLTTPTQSEREMTDS--TPVFT---ETNTLENLGAQTTEHSSI 1812
T+S G+ + +S T+ + T S T VFT ET T+ +G++ T S+
Sbjct: 1110 GSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169
Query: 1813 HQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSS--FSLNVEYAIQAEKEVAGTL 1870
+ AS + + + A ETTT S+ N +E +
Sbjct: 1170 GSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSA 1229
Query: 1871 SPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPL 1930
T F + ST A ++T + V G A ST F L
Sbjct: 1230 GSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGAT--AASTTVSSTTFVL 1287
Query: 1931 EEDFSGDFREY---------STVSHPIAKEETVMMEGSGDAAFRDTQTSPSTV--PTSVH 1979
+ + +T + P A M G A + T P V + +
Sbjct: 1288 TKATDVSIQPITNTPMSGTRTTGTRPTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLG 1347
Query: 1980 ISHISDSEGPSSTMVSTSAFPWEEFTSSA-EGSGEQLVTVSSSVVPVLPSAVQKFSG 2035
S + S S+ V T+ E TSS + +G + ++ + P+ V K SG
Sbjct: 1348 TSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPSG 1404
Score = 100 bits (250), Expect = 2e-20
Identities = 279/1377 (20%), Positives = 460/1377 (33%), Gaps = 164/1377 (11%)
Query: 522 TARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVIT 581
TA M T S + + TG + E T + S E+T+ E T
Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146
Query: 582 VSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGKYLS 641
VS +T + D E+ +ASTT S + GS IT G +
Sbjct: 147 VSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSE-----------TITPSTAGSETT 195
Query: 642 TTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTH-RRERTETLIPEMRTDTYT 700
T T + T ++ +E T +ET + ++T
Sbjct: 196 TVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTA 255
Query: 701 DEIQEEITKSPFM--GKTEEEVFSGMK---LSTSLSEPIHVTESSVEMTKSFDFPTLITK 755
++ T + F KT +G + ST+ SEP + E T + TK
Sbjct: 256 ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315
Query: 756 LSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPL 815
+S +EV + + T + TTV + + S+ S D +
Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 375
Query: 816 ESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDEDIAA 875
STE S + TT G + S T ++ T E ++ +
Sbjct: 376 ASTEGSET--------TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVS 427
Query: 876 HGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSK 935
T F+ TT++ E S + ++T + STEG T+ + +K
Sbjct: 428 ----TTVFETTTAS--TEGSEITIASTSDSETTTASTEGSETTTVTTAG-------SETK 474
Query: 936 PVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDE 995
T T+ GL + + TT + + +V V + SE+
Sbjct: 475 TAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENT 534
Query: 996 VLGEPSQDILVIDQTRLEATISPETMRTTKITEGT--TQEEFPWKEQTAEKPVPALSSTA 1053
+ + + T LE TT TEG+ T E T + + ++ A
Sbjct: 535 TVSTTGSETTTVSTTGLET--------TTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA 586
Query: 1054 WTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHK 1113
T T + + + + + ++ E + S T + + + G+ T
Sbjct: 587 STAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTV 646
Query: 1114 VKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKT 1173
TD T+ G + +++ TEGS TT +++ S +T T+ TT T
Sbjct: 647 STTDSETTMVSTTGSERTIT-------STEGSETTTVSATGSE-TTVSTEGSGTTTVSIT 698
Query: 1174 SLEDIDLG-SGLFEKPKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKK 1232
E + +G +TE E +T +T S+ TTA S + TT+A S T
Sbjct: 699 GSETTKVSTTGSETTTTSTEGSEITTASIT-GSETTTA--STEGSETTTASTEGSETTSA 755
Query: 1233 PPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTR 1292
G ETT+ E TT+ I+ ET T +S ++ T+
Sbjct: 756 -----STTGSETTTASTTSSE-------TTMASIMGSET---------TMASTIGSETTK 794
Query: 1293 PPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESK 1352
+ST +T F + I ++T +S
Sbjct: 795 --------------VSTASSKMTTVFTENSETTIASTTASETTTVS-------------- 826
Query: 1353 EDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYIN 1412
ET P +E S E E +++ TT ++
Sbjct: 827 ---TAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI---- 879
Query: 1413 GKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTE 1472
G T E +E E + ++ SE T ++T ++ +T
Sbjct: 880 GSETTTA---STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTA 936
Query: 1473 TTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQ 1532
+TE E+T T ET + G T E + TA +V+ +E
Sbjct: 937 STEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTA 996
Query: 1533 AHEHTEPVSLFPEES-SGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSA 1591
+ E +E ++ S + ++ I +E T T+ YT ++
Sbjct: 997 SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTT 1056
Query: 1592 SAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDT 1651
S SE V+ G+ + + + +E T V SGS T + A + T
Sbjct: 1057 STEGSETTTVSTTGS----ETTTASTADLETT---TVSTSGSG----TTTASTAGSETTT 1105
Query: 1652 MF---TMVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKFVSE 1708
++ + T S + T ++ +S T S TT++ VSE
Sbjct: 1106 VYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT-------------VSE 1152
Query: 1709 TDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELESPNVATSSDSG 1768
T T I S E TT T + +ST S E+ +T+
Sbjct: 1153 TTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS---------ETTTASTAGSET 1203
Query: 1769 TRKSFMSLTTPTQSEREMTDSTP--VFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLPR 1826
T S T T STP +ETNT +G++TT S+ ++ T+L
Sbjct: 1204 TTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAST---ASLEPTATSLTG 1260
Query: 1827 SPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEVAGTLSPHVETTFSTEPT 1883
S + SG AA +TTVSS + + A + T T PT
Sbjct: 1261 SETTTVSITASGATAA---STTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRPT 1314
Score = 87.4 bits (215), Expect = 2e-16
Identities = 253/1199 (21%), Positives = 427/1199 (35%), Gaps = 185/1199 (15%)
Query: 1526 DTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPT 1585
+T V A +T S E++ + E+ + A + T ++T V+ + +
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 1586 IVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQV--VELSGSSSIPITEGSG 1643
+ ++++A SE V+ G+ ++ E+ V + V ++G+ + ++
Sbjct: 64 EITTTSTAG-SENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122
Query: 1644 EAEEDEDTMF--TMVTDLSQRNTTDTLITLDTSRIITESFFEVPATT----IYPVSEQPS 1697
E + T T+ + TT + + +T+ T A+T + V S
Sbjct: 123 ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGS 182
Query: 1698 AKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELE 1757
+ P+ SET T S T E T TA + +ST S E
Sbjct: 183 ETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGS---------E 233
Query: 1758 SPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTE---TNTLENLGAQTTEHSSIHQ 1814
+ V+T+ T + S TT +E T++ FTE T T G +TT S+
Sbjct: 234 TTKVSTAGSETTVSTAGSETTAASTEDSETNTA--FTEDSKTTTASTTGFETTAAST--- 288
Query: 1815 PGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEV--AGTLSP 1872
T + AS + + + PETT VS+ S V A E A T+
Sbjct: 289 -------TGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS 341
Query: 1873 HVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPLEE 1932
TT ST + +++M + + T S S G+E ST
Sbjct: 342 ET-TTVSTTGSETTTASIMGSETSTDSTTGSETTTASTE------GSETTTASTEGSEAT 394
Query: 1933 DFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDT---QTSPSTVPTSVHISHISDSE-- 1987
S E +TVS ++ T EGS A T T+ ST + + I+ SDSE
Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454
Query: 1988 -----GPSSTMVSTS------AFPWEEFTSSAEGSGEQLVTV--------SSSVVPVLPS 2028
G +T V+T+ A+ T++A +G + TV ++S +
Sbjct: 455 TASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514
Query: 2029 AVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNF 2088
AV +++ EG E TV+ +T + T +E T E E+ TVST
Sbjct: 515 AVSATGSEMTTVSTEG-SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMT---TVSTTG 570
Query: 2089 PQTIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTET 2148
+T + S TT+ E + S +S T + DS+T T
Sbjct: 571 AETTTDSTEGSG-------------TTAASTAGSETTTVSTADSENTTASTADSET---T 614
Query: 2149 ELKTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATEKSHFFLA 2208
TT T T S+ E + +ST D S TT+ T
Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTD-------SETTMVSTTG------- 660
Query: 2209 TALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLPT 2268
+E +T + + E+T T+ + +E S GSG T
Sbjct: 661 ---------SERTITST--EGSETT---------TVSATGSETTVSTEGSGTT------T 694
Query: 2269 ESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVT 2328
S+ +E +++ T S+ +TS++ E A G S+T GS T
Sbjct: 695 VSITGSETTKVSTT----GSETTTTSTEGSEI-----TTASITG---SETTTASTEGSET 742
Query: 2329 STTLIE-----ILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSN 2383
+T E S TG+E T + T + A I S ++ S
Sbjct: 743 TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIG-SETTKVSTASSK 801
Query: 2384 KNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPSDLYYEPSGEGSGEVDIVDSFH 2443
+ E +ETT +ST A E T + S+ P+ E
Sbjct: 802 MTTVFTENSETTIASTT----------ASETTTVSTAGSETI--PASTAGSE-------- 841
Query: 2444 TSATTQATRQESSTTFVSDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSEQNKSSPDPT 2503
+ TT +T +TT ++GS E +A +++ ++ + + S T
Sbjct: 842 -TTTTTSTEGSETTTASTEGS-----ETTTASTESSETTTATTIGSETTTASTEGSETTT 895
Query: 2504 STLSNTVSYERSTDGSFQDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDLILTITESTI 2563
++ + + ST+GS E +T+ + T E + TE +
Sbjct: 896 TSTEGSETTTASTEGS--------EITTVSTTGSETT-----TASTEGSETTTASTEGSE 942
Query: 2564 LEILPELTSDKNTIIDIDHTKPVYEDILGMQTDIDTEVPSEPHDSNDESNDDSTQVQEIY 2623
L + T + + + ++ +G +T + SE + ++ +T E
Sbjct: 943 LTTV-STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGS 1001
Query: 2624 EAAVNLSLTEETFEGSADVLASYTQATHDESMTYEDRSQLDHMGFHFTTGIPAPSTETE 2682
E S ET S + +T T + + +TTG +T TE
Sbjct: 1002 ETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV-YTTGSETTTTSTE 1059
Score = 60.8 bits (146), Expect = 2e-08
Identities = 181/835 (21%), Positives = 275/835 (32%), Gaps = 122/835 (14%)
Query: 528 ESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVITVSKT-S 586
E+ T S + T G T+ D E ++ E T+ + E TVS T S
Sbjct: 622 ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 681
Query: 587 EDTIHTH--------LEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGK 638
E T+ T + E+ STT S GS + T+ IT G
Sbjct: 682 ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI-------TTASIT----GS 730
Query: 639 YLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRERTETLIPEMRTDT 698
+T EG T T T E T T T
Sbjct: 731 ETTTAS--------------------TEGSETT------TASTEGSETTSASTTGSETTT 764
Query: 699 YTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMTKSFDFPTLITKLSA 758
E T + MG ST SE V+ +S +MT F + T S
Sbjct: 765 -ASTTSSETTMASIMGS------ETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817
Query: 759 EPTEVRDMEEDFTAT-PGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPLES 817
+E + + T P +T E TT S E + + S + TT+ ES
Sbjct: 818 TASETTTVSTAGSETIPASTAGSETTTTT-------STEGSETTTASTEGSETTTASTES 870
Query: 818 TEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDED---IA 874
+E + ++ + + TT G + S +G++ T + ++ T + +
Sbjct: 871 SETTTATTI-GSETTTASTEGSETTTTS--TEGSETTTASTEGSEITTVSTTGSETTTAS 927
Query: 875 AHGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLS 934
G T T ST +E +T+ + +E +E TM +
Sbjct: 928 TEGSET----TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSET 983
Query: 935 KPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWG---------- 984
VST T+ +EG + SST TT V ++ T + I T+
Sbjct: 984 TTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT--ETTITSTEGSETTTVTTAGS 1041
Query: 985 --VLVPSVPSEDEVLGEPSQDILVIDQTRLE-ATISPETMRTTKIT---EGTTQEEFPWK 1038
V + SE + + T E T S + TT ++ GTT
Sbjct: 1042 ETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGS 1101
Query: 1039 EQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKI 1098
E T + ++TA T T + + + + + E+ T V ETT V I
Sbjct: 1102 ETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT--VFTTVSETTTVSTI 1159
Query: 1099 DHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFS 1158
+ A +E + E T S + T GS TT ++S S +
Sbjct: 1160 GSEATTSSAAGSEATTTSTEGSETT-----TASTAGSETTTASTAGSETTTASTSGSETN 1214
Query: 1159 THITQLMEETTTEKTSLE---------DIDLGSGLFEKPKATELIEFSTIKVTVPSDITT 1209
T T E +T E + + S +P AT L T V++ + T
Sbjct: 1215 TACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGAT 1274
Query: 1210 AFSSVDRLHTTSAFKPSSA----ITKKPPLIDREPGEETTSD--------MVIIGESTSH 1257
A S+ T K + IT P R G T+ M + SH
Sbjct: 1275 AASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRPTASSSVTMAPGMDFTASAASH 1334
Query: 1258 VPPTTLEDIVAKETETDIDREYFTTSS---PPATQPTRPPTVEDKEAFGPQALST 1309
P + + T T TTS+ T TR PT + GP ++ T
Sbjct: 1335 TVPGIVLNTSGLGTST--MGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGT 1387
>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1521
Score = 124 bits (310), Expect = 2e-27
Identities = 298/1402 (21%), Positives = 474/1402 (33%), Gaps = 100/1402 (7%)
Query: 1093 TPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPR-IGPKVSLSPGPEQKYETEGSSTTGFT 1151
+P G VS +T E T++ G + G E T GS TT
Sbjct: 49 SPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT-V 107
Query: 1152 SSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDITTAF 1211
S +T ++ + ETTT T+ + + S + + T TTA
Sbjct: 108 SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAA 167
Query: 1212 SSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKET 1271
S+ TT S IT G ETT+ + G T+ V T E A
Sbjct: 168 STTGSEMTTVFTAGSETITPSTA------GSETTT-VSTAGSETTTVSTTGSETTTASTA 220
Query: 1272 ETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRE 1331
++ S T A ST +T F D
Sbjct: 221 HSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTG 280
Query: 1332 NKTGRMSDLS---VIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEE 1388
+T S + + SE+ ET V +E+ F E +
Sbjct: 281 FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSET--IRAST 338
Query: 1389 NEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSE 1448
E + TTT S+ G T E A E+ S ++ SE
Sbjct: 339 VGSETTTVSTTGSETTTASIM---GSETSTDSTTGSETTTASTEGSETTTAS---TEGSE 392
Query: 1449 SDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHE 1508
+ T ++T + +T TE E+T T ET+ + G + E
Sbjct: 393 ATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSE 452
Query: 1509 EFESGTAKKGAESVTER--DTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARAT 1566
+ T +VT +T+ + T S E++ I ++ A +
Sbjct: 453 TTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-ASTEGS 511
Query: 1567 EVTFGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQ 1626
E T + T ++ S SE V+ G L T + E +
Sbjct: 512 ETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG-------LETTTTSTEGSEMT 564
Query: 1627 VVELSGS-SSIPITEGSGE-AEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEV 1684
V +G+ ++ TEGSG A + T V+ NTT + +T+ T
Sbjct: 565 TVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETT 624
Query: 1685 PATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEG---TTGTASTFEVY 1741
A+T + S + T VS TD+ + STT E+ EG TT +A+ E
Sbjct: 625 TASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684
Query: 1742 SSTQRSDQLILPFE-LESPNVATSSDSGTRKSF--MSLTTPTQSEREMTDSTPVFTETNT 1798
ST+ S + E+ V+T+ T S +TT + + E T ++ +ET T
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT 744
Query: 1799 LENLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFS--LNV 1856
G++TT S+ T+ + AS+ + + + ETT VS+ S +
Sbjct: 745 ASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTT 804
Query: 1857 EYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPN 1916
+ +E +A T + T + + ST T+ S S E
Sbjct: 805 VFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETT 864
Query: 1917 YGA-EIRGFSTGFPLEED---FSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPS 1972
+ E +T + + S + E +T S ++ T EGS T + +
Sbjct: 865 TASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETT 924
Query: 1973 TVPTSVHISHISDSEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQK 2032
T T + + +EG T VST+ E T SAEGS VT S
Sbjct: 925 TASTEGSETTTASTEGSELTTVSTTGS--ETITVSAEGSETTTVTTMGSETTT------- 975
Query: 2033 FSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQTI 2092
+ TA S E TV+ +T TA +EG++ + TVST +T
Sbjct: 976 -ASTAGS-------ETTTVSTAGSETT---TASIEGSETTTVSSTGSETTTVSTTGTETT 1024
Query: 2093 EPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTET--EL 2150
+ S E V SETT+ E + S + S T + S+T T + +L
Sbjct: 1025 ITSTEGS--ETTTV-TTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADL 1081
Query: 2151 KTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATE-KSHFFLAT 2209
+TT S + T + + + T G E+ T ++E + +
Sbjct: 1082 ETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGS 1141
Query: 2210 ALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTE-LLFSGLGSGEEVLPTLPT 2268
+ T T S I E +T T +E S GS T +
Sbjct: 1142 EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGS 1201
Query: 2269 ESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVT 2328
E+ + NT S+ + SS G + I ++
Sbjct: 1202 ETTTASTSGSETNTACTTGSETSTPSS---------------AGSETNTAFIIGSESTIA 1246
Query: 2329 STTLIE--ILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSNKNS 2386
ST +E S TG+E TV+ + + TV + T + +N
Sbjct: 1247 STASLEPTATSLTGSETTTVS---ITASGATAASTTVSSTTFVLTKATDVSIQPITNTPM 1303
Query: 2387 STAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPS--DLYYEPSGEGS---GEVDIVDS 2441
S T +++ + A G +F SA + + SG G+ G +
Sbjct: 1304 SGTRTTGTRLTASSSVTMAPGM----DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSA 1359
Query: 2442 FHTSATTQATRQESSTTFVSDG 2463
TT +TR+ +S+TF G
Sbjct: 1360 HGVRTTTGSTREPTSSTFQETG 1381
Score = 99.8 bits (247), Expect = 4e-20
Identities = 328/1527 (21%), Positives = 520/1527 (34%), Gaps = 225/1527 (14%)
Query: 566 SDESTLIFDQIPEVITVSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEER 625
S E+T+ T S T +T ++ E+ +AST S P GS
Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGS-------- 53
Query: 626 QTSGRITEEFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRE 685
QT+ G ++TT T + + G T + + T
Sbjct: 54 QTT---IVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSIT 110
Query: 686 RTE-TLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMT 744
TE T++ M ++T T+ T ST+ SE V+ E T
Sbjct: 111 GTETTMVSAMGSETTTNSTTSSET---------------TVTSTAGSETTTVSTVGSETT 155
Query: 745 KSFDFPTLITKLSAEPTEVRDMEEDFTA-----TPGTTKYDENITTVLLAHGTLSVEAAT 799
++ T ++ +A T +M FTA TP T TTV A + + T
Sbjct: 156 TAY---TADSETTAASTTGSEMTTVFTAGSETITPSTA--GSETTTVSTAGSETTTVSTT 210
Query: 800 VSKWSWDEDNTTSKPLESTEPSASSKLPPA-LLTTVGMNGKDKDIPSFTEDGADEFTLIP 858
S+ + + ST S ++K+ A TTV G + S TED
Sbjct: 211 GSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAAS-TEDSETNTAFTE 269
Query: 859 DSTQKQLEEVTDEDIAAHGKFTIRFQPTTSTGIAEKSTLRDSTTEE--KVPPITSTEGQV 916
DS E AA T +PT ++ + ++T+ + E KV +S V
Sbjct: 270 DSKTTTASTTGFETTAAS---TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV 326
Query: 917 YA----TMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHT 972
+A T+ S +G + VST T+ + G + S+T TT +
Sbjct: 327 FAAGSETIRASTVGSE-----TTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTE-- 379
Query: 973 IPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEATI--SPETMRTTKITEGT 1030
SE + + T E T ++ TT TEG+
Sbjct: 380 ------------------GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGS 421
Query: 1031 TQEEFPWKEQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVL 1090
E TA ++TA T +T + S+ E T S
Sbjct: 422 --------EMTAVSTTVFETTTASTEGSEIT----------IASTSDSETTTASTEGSET 463
Query: 1091 ETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGF 1150
T + +Y G+ T T T IG + + TEGS TT
Sbjct: 464 TTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA-------STEGSETTAV 516
Query: 1151 TSSLSPFSTHITQLMEETTTEKTSLEDIDLG-SGLFEKPKATELIEFSTIKVTVPSDITT 1209
+++ S +T T+ E TT T E + +GL +TE E +T+ T T
Sbjct: 517 SATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT---GAET 573
Query: 1210 AFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAK 1269
S + TT+A S T D E +T+D ST+ TT ++
Sbjct: 574 TTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632
Query: 1270 ETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEV 1329
T + TT S ++ T T + S ++T ++
Sbjct: 633 TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS------ 686
Query: 1330 RENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEEN 1389
+ + +S+ G SE+ + ET +EI E +E +
Sbjct: 687 --TEGSGTTTVSITG----SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740
Query: 1390 EEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSES 1449
E TTT S + G + E A E+ S S+++ +
Sbjct: 741 E------------TTTASTE---GSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785
Query: 1450 DTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEE 1509
T + ++T + +T TE+ E T T ET+ + G + P E
Sbjct: 786 ST---IGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS-ETIPASTAGSE 841
Query: 1510 FESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVT 1569
+ T+ +G+E+ T TE TE E++ I E+ T T
Sbjct: 842 TTTTTSTEGSETTT-ASTEGSETTTASTE-----SSETTTATTIGSET-------TTAST 888
Query: 1570 FGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPW---PDDLLSTKESWVEATPRQ 1626
G E T+ T T ++AS SE V+ G+ + T + E +
Sbjct: 889 EGSE----TTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELT 944
Query: 1627 VVELSGSSSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEVPA 1686
V +GS +I ++ G TM + T S + T ++ S T S
Sbjct: 945 TVSTTGSETITVS-AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET 1003
Query: 1687 TTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQR 1746
TT+ + T VS T T I+ST E TT + T VY++
Sbjct: 1004 TTVSSTGSE-------TTTVSTTGTETTITSTEGSETTTV----TTAGSETTAVYTT--- 1049
Query: 1747 SDQLILPFELESPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTETNTLENLGAQT 1806
T+S G+ TT + + E T ++ ET T+ G+ T
Sbjct: 1050 -----------GSETTTTSTEGS-----ETTTVSTTGSETTTASTADLETTTVSTSGSGT 1093
Query: 1807 TEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEV 1866
T S+ G + + S + +GS E TTVS+ S +E
Sbjct: 1094 TTAST---AGSETTTVYITGSKTTTASTEGS-------EATTVSTTS--------SETTT 1135
Query: 1867 AGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFST 1926
A T + T F+T +ST+ T+ SE G+E ST
Sbjct: 1136 ASTTGSEMTTVFTTVSETTTVSTIGSEA-------TTSSAAGSEATTTSTEGSETTTAST 1188
Query: 1927 GFPLEEDFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVPTSVHISHISDS 1986
S E +T S ++ T GS +T T PS+ + + + I S
Sbjct: 1189 AGSETTTASTAGSETTTASTSGSETNTACTTGS------ETST-PSSAGSETNTAFIIGS 1241
Query: 1987 EGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQKFSGTASSIIDEGLG 2046
E ST+ ST++ E +S GS V++++S + V + + D +
Sbjct: 1242 E---STIASTASL--EPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQ 1296
Query: 2047 EVGTVNEIDRRST-ILPTAEVEGTKAP 2072
+ R+T TA T AP
Sbjct: 1297 PITNTPMSGTRTTGTRLTASSSVTMAP 1323
Score = 99.0 bits (245), Expect = 7e-20
Identities = 273/1345 (20%), Positives = 452/1345 (33%), Gaps = 164/1345 (12%)
Query: 522 TARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVIT 581
TA M T S + + TG + E T + S E+T+ E T
Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146
Query: 582 VSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGKYLS 641
VS +T + D E+ +ASTT S + GS IT G +
Sbjct: 147 VSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSE-----------TITPSTAGSETT 195
Query: 642 TTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTH-RRERTETLIPEMRTDTYT 700
T T + T ++ +E T +ET + ++T
Sbjct: 196 TVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTA 255
Query: 701 DEIQEEITKSPFM--GKTEEEVFSGMK---LSTSLSEPIHVTESSVEMTKSFDFPTLITK 755
++ T + F KT +G + ST+ SEP + E T + TK
Sbjct: 256 ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315
Query: 756 LSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPL 815
+S +EV + + T + TTV + + S+ S D +
Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 375
Query: 816 ESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDEDIAA 875
STE S + TT G + S T ++ T E ++ +
Sbjct: 376 ASTEGSET--------TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVS 427
Query: 876 HGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSK 935
T F+ TT++ E S + ++T + STEG T+ + +K
Sbjct: 428 ----TTVFETTTAS--TEGSEITIASTSDSETTTASTEGSETTTVTTAG-------SETK 474
Query: 936 PVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDE 995
T T+ GL + + TT + + +V V + SE+
Sbjct: 475 TAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENT 534
Query: 996 VLGEPSQDILVIDQTRLEATISPETMRTTKITEGT--TQEEFPWKEQTAEKPVPALSSTA 1053
+ + + T LE TT TEG+ T E T + + ++ A
Sbjct: 535 TVSTTGSETTTVSTTGLET--------TTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA 586
Query: 1054 WTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHK 1113
T T + + + + + ++ E + S T + + + G+ T
Sbjct: 587 STAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTV 646
Query: 1114 VKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKT 1173
TD T+ G + +++ TEGS TT +++ S +T T+ TT T
Sbjct: 647 STTDSETTMVSTTGSERTIT-------STEGSETTTVSATGSE-TTVSTEGSGTTTVSIT 698
Query: 1174 SLEDIDLG-SGLFEKPKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKK 1232
E + +G +TE E +T +T S+ TTA S + TT+A S T
Sbjct: 699 GSETTKVSTTGSETTTTSTEGSEITTASIT-GSETTTA--STEGSETTTASTEGSETTSA 755
Query: 1233 PPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTR 1292
G ETT+ E TT+ I+ ET T +S ++ T+
Sbjct: 756 -----STTGSETTTASTTSSE-------TTMASIMGSET---------TMASTIGSETTK 794
Query: 1293 PPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESK 1352
+ST +T F + I ++T +S
Sbjct: 795 --------------VSTASSKMTTVFTENSETTIASTTASETTTVS-------------- 826
Query: 1353 EDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYIN 1412
ET P +E S E E +++ TT ++
Sbjct: 827 ---TAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI---- 879
Query: 1413 GKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTE 1472
G T E +E E + ++ SE T ++T ++ +T
Sbjct: 880 GSETTTA---STEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTA 936
Query: 1473 TTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQ 1532
+TE E+T T ET + G T E + TA +V+ +E
Sbjct: 937 STEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTA 996
Query: 1533 AHEHTEPVSLFPEES-SGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSA 1591
+ E +E ++ S + ++ I +E T T+ YT ++
Sbjct: 997 SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTT 1056
Query: 1592 SAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDT 1651
S SE V+ G+ + + + +E T V SGS T + A + T
Sbjct: 1057 STEGSETTTVSTTGS----ETTTASTADLETT---TVSTSGSG----TTTASTAGSETTT 1105
Query: 1652 MF---TMVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKFVSE 1708
++ + T S + T ++ +S T S TT++ VSE
Sbjct: 1106 VYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT-------------VSE 1152
Query: 1709 TDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELESPNVATSSDSG 1768
T T I S E TT T + +ST S E+ +T+
Sbjct: 1153 TTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS---------ETTTASTAGSET 1203
Query: 1769 TRKSFMSLTTPTQSEREMTDSTP--VFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLPR 1826
T S T T STP +ETNT +G+++T S+ ++ T+L
Sbjct: 1204 TTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIAST---ASLEPTATSLTG 1260
Query: 1827 SPASVFMEQGSGEAAADPETTTVSS 1851
S + SG AA +TTVSS
Sbjct: 1261 SETTTVSITASGATAA---STTVSS 1282
Score = 87.4 bits (215), Expect = 2e-16
Identities = 253/1199 (21%), Positives = 427/1199 (35%), Gaps = 185/1199 (15%)
Query: 1526 DTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPT 1585
+T V A +T S E++ + E+ + A + T ++T V+ + +
Sbjct: 4 ETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGS 63
Query: 1586 IVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQV--VELSGSSSIPITEGSG 1643
+ ++++A SE V+ G+ ++ E+ V + V ++G+ + ++
Sbjct: 64 EITTTSTAG-SENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGS 122
Query: 1644 EAEEDEDTMF--TMVTDLSQRNTTDTLITLDTSRIITESFFEVPATT----IYPVSEQPS 1697
E + T T+ + TT + + +T+ T A+T + V S
Sbjct: 123 ETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGS 182
Query: 1698 AKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELE 1757
+ P+ SET T S T E T TA + +ST S E
Sbjct: 183 ETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGS---------E 233
Query: 1758 SPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTE---TNTLENLGAQTTEHSSIHQ 1814
+ V+T+ T + S TT +E T++ FTE T T G +TT S+
Sbjct: 234 TTKVSTAGSETTVSTAGSETTAASTEDSETNTA--FTEDSKTTTASTTGFETTAAST--- 288
Query: 1815 PGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEV--AGTLSP 1872
T + AS + + + PETT VS+ S V A E A T+
Sbjct: 289 -------TGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGS 341
Query: 1873 HVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPLEE 1932
TT ST + +++M + + T S S G+E ST
Sbjct: 342 ET-TTVSTTGSETTTASIMGSETSTDSTTGSETTTASTE------GSETTTASTEGSEAT 394
Query: 1933 DFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDT---QTSPSTVPTSVHISHISDSE-- 1987
S E +TVS ++ T EGS A T T+ ST + + I+ SDSE
Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454
Query: 1988 -----GPSSTMVSTS------AFPWEEFTSSAEGSGEQLVTV--------SSSVVPVLPS 2028
G +T V+T+ A+ T++A +G + TV ++S +
Sbjct: 455 TASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETT 514
Query: 2029 AVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNF 2088
AV +++ EG E TV+ +T + T +E T E E+ TVST
Sbjct: 515 AVSATGSEMTTVSTEG-SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMT---TVSTTG 570
Query: 2089 PQTIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTET 2148
+T + S TT+ E + S +S T + DS+T T
Sbjct: 571 AETTTDSTEGSG-------------TTAASTAGSETTTVSTADSENTTASTADSET---T 614
Query: 2149 ELKTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATEKSHFFLA 2208
TT T T S+ E + +ST D S TT+ T
Sbjct: 615 SASTTGSETTTASTTSSETTTASTEGSETTTVSTTD-------SETTMVSTTG------- 660
Query: 2209 TALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLPT 2268
+E +T + + E+T T+ + +E S GSG T
Sbjct: 661 ---------SERTITST--EGSETT---------TVSATGSETTVSTEGSGTT------T 694
Query: 2269 ESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVT 2328
S+ +E +++ T S+ +TS++ E A G S+T GS T
Sbjct: 695 VSITGSETTKVSTT----GSETTTTSTEGSEI-----TTASITG---SETTTASTEGSET 742
Query: 2329 STTLIE-----ILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSN 2383
+T E S TG+E T + T + A I S ++ S
Sbjct: 743 TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIG-SETTKVSTASSK 801
Query: 2384 KNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPSDLYYEPSGEGSGEVDIVDSFH 2443
+ E +ETT +ST A E T + S+ P+ E
Sbjct: 802 MTTVFTENSETTIASTT----------ASETTTVSTAGSETI--PASTAGSE-------- 841
Query: 2444 TSATTQATRQESSTTFVSDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSEQNKSSPDPT 2503
+ TT +T +TT ++GS E +A +++ ++ + + S T
Sbjct: 842 -TTTTTSTEGSETTTASTEGS-----ETTTASTESSETTTATTIGSETTTASTEGSETTT 895
Query: 2504 STLSNTVSYERSTDGSFQDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDLILTITESTI 2563
++ + + ST+GS E +T+ + T E + TE +
Sbjct: 896 TSTEGSETTTASTEGS--------EITTVSTTGSETT-----TASTEGSETTTASTEGSE 942
Query: 2564 LEILPELTSDKNTIIDIDHTKPVYEDILGMQTDIDTEVPSEPHDSNDESNDDSTQVQEIY 2623
L + T + + + ++ +G +T + SE + ++ +T E
Sbjct: 943 LTTV-STTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGS 1001
Query: 2624 EAAVNLSLTEETFEGSADVLASYTQATHDESMTYEDRSQLDHMGFHFTTGIPAPSTETE 2682
E S ET S + +T T + + +TTG +T TE
Sbjct: 1002 ETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV-YTTGSETTTTSTE 1059
Score = 61.6 bits (148), Expect = 1e-08
Identities = 178/834 (21%), Positives = 275/834 (32%), Gaps = 120/834 (14%)
Query: 528 ESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVITVSKT-S 586
E+ T S + T G T+ D E ++ E T+ + E TVS T S
Sbjct: 622 ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 681
Query: 587 EDTIHTH--------LEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGK 638
E T+ T + E+ STT S GS + T+ IT G
Sbjct: 682 ETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI-------TTASIT----GS 730
Query: 639 YLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRERTETLIPEMRTDT 698
+T EG T T T E T T T
Sbjct: 731 ETTTAS--------------------TEGSETT------TASTEGSETTSASTTGSETTT 764
Query: 699 YTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMTKSFDFPTLITKLSA 758
E T + MG ST SE V+ +S +MT F + T S
Sbjct: 765 -ASTTSSETTMASIMGS------ETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817
Query: 759 EPTEVRDMEEDFTAT-PGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPLES 817
+E + + T P +T E TT S E + + S + TT+ ES
Sbjct: 818 TASETTTVSTAGSETIPASTAGSETTTTT-------STEGSETTTASTEGSETTTASTES 870
Query: 818 TEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDED---IA 874
+E + ++ + + TT G + S +G++ T + ++ T + +
Sbjct: 871 SETTTATTI-GSETTTASTEGSETTTTS--TEGSETTTASTEGSEITTVSTTGSETTTAS 927
Query: 875 AHGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLS 934
G T T ST +E +T+ + +E +E TM +
Sbjct: 928 TEGSET----TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSET 983
Query: 935 KPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWG---------- 984
VST T+ +EG + SST TT V ++ T + I T+
Sbjct: 984 TTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT--ETTITSTEGSETTTVTTAGS 1041
Query: 985 --VLVPSVPSEDEVLGEPSQDILVIDQTRLE-ATISPETMRTTKIT---EGTTQEEFPWK 1038
V + SE + + T E T S + TT ++ GTT
Sbjct: 1042 ETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGS 1101
Query: 1039 EQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKI 1098
E T + ++TA T T + + + + + E+ T V ETT V I
Sbjct: 1102 ETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT--VFTTVSETTTVSTI 1159
Query: 1099 DHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFS 1158
+ A +E + E T S + T GS TT ++S S +
Sbjct: 1160 GSEATTSSAAGSEATTTSTEGSETT-----TASTAGSETTTASTAGSETTTASTSGSETN 1214
Query: 1159 THITQLMEETTTEKTSLE---------DIDLGSGLFEKPKATELIEFSTIKVTVPSDITT 1209
T T E +T E + + S +P AT L T V++ + T
Sbjct: 1215 TACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITASGAT 1274
Query: 1210 AFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAK 1269
A +S TT ++ ++ +P G TT + S + P A
Sbjct: 1275 A-ASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAAS 1333
Query: 1270 ETETDI--DREYFTTSSPPA------------TQPTRPPTVEDKEAFGPQALST 1309
T I + TS+ A T TR PT + GP ++ T
Sbjct: 1334 HTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGT 1387
>gi|83367077 mucin 16 [Homo sapiens]
Length = 14507
Score = 120 bits (302), Expect = 2e-26
Identities = 596/2938 (20%), Positives = 1007/2938 (34%), Gaps = 502/2938 (17%)
Query: 350 EATTIDLSILAETASPSLSKEPQMVSDRTTPIIPLVDELPVIP-----TEFPPVGNIVSF 404
E TTI SI P SK + ++ T+ + P + E + TE V
Sbjct: 4868 EDTTISRSI------PKSSKTTRTETETTSSLTPKLRETSISQEITSSTETSTVPYKELT 4921
Query: 405 EQKATVQPQAITDSLATKLPTPTGSTKKPWDMDDYSPSASGPLGKLDISEIKEEVLQSTT 464
V +T S +T P P ST D S + L I E+ +T
Sbjct: 4922 GATTEVSRTDVTSSSSTSFPGPDQSTVSL----DISTETNTRLSTSPIMTESAEITITTQ 4977
Query: 465 GVSHYATDSWDGVVEDKQT------QESVTQ-IEQIEVGPLV---------TSMEILKHI 508
H AT ++ T ++T Q++V L+ TS +
Sbjct: 4978 TGPHGATSQDTFTMDPSNTTPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVDKT 5037
Query: 509 PSKEFPVTETPLVTARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDE 568
S ++ + T +I + E K+ S ++ L+T+G T D RT
Sbjct: 5038 SSPSSFLSSPAMTTPSLISSTLPEDKLSSPMTSLLTSGLVKIT-----DILRTRLEPVTS 5092
Query: 569 STLIFDQIPE-VITVSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQT 627
S F + ++ SK S+DT + P I + ++
Sbjct: 5093 SLPNFSSTSDKILATSKDSKDT--------------KEIFPSINTEETNVKANNSGHESH 5138
Query: 628 SGRITEEFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRERT 687
S + + S TP + T++ + GD S ++ S +T +RE T
Sbjct: 5139 SPALAD-------SETP---KATTQMVITTTVGDP--APSTSMPVHGSSETTNI-KREPT 5185
Query: 688 ETLIPEMRTDTYTDEIQEEITKSPFM------GKTEEEVFSGMKLSTSLSEPIHVTESSV 741
L P +R +T T + T + F+ G E +G+ S+ +S P H +
Sbjct: 5186 YFLTPRLR-ETSTSQESSFPTDTSFLLSKVPTGTITEVSSTGVNSSSKISTPDHDKSTVP 5244
Query: 742 EMTKSFDFPTLITKL----SAEPTEVRDMEEDFTATPGTTKYDENIT------------- 784
T + + P + T SAE T +A+ T D + T
Sbjct: 5245 PDTFTGEIPRVFTSSIKTKSAEMTITTQASPPESASHSTLPLDTSTTLSQGGTHSTVTQG 5304
Query: 785 ------TVLLAHGTLSV---------EAATVSKWSWDEDNTTSKPLESTEPSA--SSKLP 827
T L+ G +V E ++VS T+ P+ ST P + SS LP
Sbjct: 5305 FPYSEVTTLMGMGPGNVSWMTTPPVEETSSVSSLMSSPAMTSPSPVSSTSPQSIPSSPLP 5364
Query: 828 ------PALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDEDIAAHGKFTI 881
L+TT + G P + I ++ + A H
Sbjct: 5365 VTALPTSVLVTTTDVLGTTS--PESVTSSPPNLSSITHERPATYKDTAHTEAAMHHSTNT 5422
Query: 882 RFQPTTSTGIAEKS---TLRDSTTEEKVPPI--TSTEGQVYATMEGSALGEVEDVDLSKP 936
++G KS L DS T + P + TST G + + + +
Sbjct: 5423 AVTNVGTSGSGHKSQSSVLADSETSKATPLMSTTSTLGDTSVSTSTPNISQTNQIQTEPT 5482
Query: 937 VSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDEV 996
S P+ +S E SST E T T ++ +T+ S+ D
Sbjct: 5483 ASLSPRLRESSTSE-----KTSSTTETNTAFSYVPTGAITQASRTEISSSRTSISDLDRP 5537
Query: 997 LGEPSQDILVIDQ--TRLEATISPETMRTTKITE--GTTQEEFPWKEQTA--EKPVPALS 1050
P +I + T T S E TT+ T T+Q PW T + +
Sbjct: 5538 TIAPDISTGMITRLFTSPIMTKSAEMTVTTQTTTPGATSQGILPWDTSTTLFQGGTHSTV 5597
Query: 1051 STAWTPKEAVTPLDEQEGDGSAYTVSE-DELLTGSERVPVLETTPVGKIDHSV-SYPPGA 1108
S + E T GD S T +E +G + T+P S S P
Sbjct: 5598 SQGFPHSEITTLRSRTPGDVSWMTTPPVEETSSGFSLMSPSMTSPSPVSSTSPESIPSSP 5657
Query: 1109 VTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEET 1168
+ + T +VT T +G + SP P SS T + + H T+ M +
Sbjct: 5658 LPVTALLTSVLVTTTNVLG---TTSPEPVTSSPPNLSSPTQERLTTYKDTAH-TEAMHAS 5713
Query: 1169 TTEKTSLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSA 1228
T++ ++ E + + T K T P IT A +T AF +
Sbjct: 5714 MHTNTAVANVGTSISGHESQSSVPA-DSHTSKATSPMGITFAMGDTSVSTSTPAFFETRI 5772
Query: 1229 ITKK-----PPLIDREPGEETTSDMVIIGEST--SHVPPTTLEDIVAKETETDIDREYFT 1281
T+ P L D EE + + ST S VP TT ++ + T++ T
Sbjct: 5773 QTESTSSLIPGLRDTRTSEEINT---VTETSTVLSEVPTTTTTEV----SRTEVITSSRT 5825
Query: 1282 TSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRENKTGRMSDLS 1341
T S P D P + ST P + N+TG + +S
Sbjct: 5826 TISGP-----------DHSKMSPYISTETITRLST--FPFVTGSTEMAITNQTGPIGTIS 5872
Query: 1342 VIGHPIDSESK-----------EDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENE 1390
+D+ S + P SEET + + + P +E E
Sbjct: 5873 QATLTLDTSSTASWEGTHSPVTQRFPHSEETTTMSRSTKGVSWQSPPSVE---------E 5923
Query: 1391 EEEEECANATDVTTTPSVQY--INGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSE 1448
T+ S Y ++G + +P RR + + SS
Sbjct: 5924 TSSPSSPVPLPAITSHSSLYSAVSGSSPTSALPVTSLLTSGRRKTIDMLDTHSELVTSSL 5983
Query: 1449 SDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHE 1508
F S + +E++ TE++ + E ET+ + + +V H
Sbjct: 5984 PSASSF-------SGEILTSEASTNTETIHFS---ENTAETNMGTTNSMHKLHSSVSIHS 6033
Query: 1509 EFESGTAKKGAESVTER---------DTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQK 1559
+ T K S+ E E + + T P++ +E S + ++ ++
Sbjct: 6034 QPSGHTPPKVTGSMMEDAIVSTSTPGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTES 6093
Query: 1560 IAFARATEVTFGEEVEKSTSVTYTPTIVPSSASAYVSEE---EAVTLIGNPWPDDLLSTK 1616
+ + EV ++ Y PT +P+SA + S + EA + N P + + K
Sbjct: 6094 NTVFSSVSLDAATEVSRAEVTYYDPTFMPASAQSTKSPDISPEASSSHSNSPPLTISTHK 6153
Query: 1617 ESWVEATPRQVVELS----GSSSIPITEGSGEAEE----DEDTMFTMVTDL--------- 1659
+ P V L +S+I + G+ A D +T M DL
Sbjct: 6154 TIATQTGPSGVTSLGQLTLDTSTIATSAGTPSARTQDFVDSETTSVMNNDLNDVLKTSPF 6213
Query: 1660 ------------------SQRNTTDTLITLDTSRIITESFFEVPATTIYPVSEQPS---- 1697
S T TL TS ++ S VP T+ +++ +
Sbjct: 6214 SAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSSLV--SVTSVPTPTLAKITDMDTNLEP 6271
Query: 1698 AKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELE 1757
P + TSE + T GT S+ + T D P++
Sbjct: 6272 VTRSPQNLRNTLATSEATTDTHTMHPSINTAVANVGTTSSPNEFYFTVSPDS--DPYKAT 6329
Query: 1758 SPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFT------ETNTLENLGAQTTEHSS 1811
S V TS+ S +S + P S + +S F+ ET+T + +G+ +++ S+
Sbjct: 6330 SAVVITSTSG---DSIVSTSMPRSSAMKKIESETTFSLIFRLRETSTSQKIGS-SSDTST 6385
Query: 1812 IHQPGVQEGLTTLPR---SPASVFMEQGSGEAAADPETTT--VSSFSLNVEYAIQAEKEV 1866
+ T + R + +S QG+ + P+T+T V+ S E+ +
Sbjct: 6386 VFDKAFTAATTEVSRTELTSSSRTSIQGTEKPTMSPDTSTRSVTMLSTFAGLTKSEERTI 6445
Query: 1867 AGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFST 1926
A PH T+ T ++T + A GFS
Sbjct: 6446 ATQTGPHRATSQGTLTWDTSITTSQ----------------------AGTHSAMTHGFS- 6482
Query: 1927 GFPLE-EDFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVPTSVHISHISD 1985
L+ + EY + + P + E+T S TSPS VPT++
Sbjct: 6483 --QLDLSTLTSRVPEYISGTSPPSVEKT---SSSSSLLSLPAITSPSPVPTTL------- 6530
Query: 1986 SEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQKFSGTASSIIDEGL 2045
E S+ V ++ P TS + + L +V +S+ P L S K T+ I D
Sbjct: 6531 PESRPSSPVHLTSLP----TSGLVKTTDMLASV-ASLPPNLGSTSHKIPTTSEDIKDTEK 6585
Query: 2046 GEVGTVNEIDRRSTILPTAEVEG-TKAPVEKEEVKVSGTVSTNF--PQTIEPAKLWSRQE 2102
T + T T+E E + P E KV+ + T+F TI + E
Sbjct: 6586 MYPSTNIAVTNVGT--TTSEKESYSSVPAYSEPPKVTSPMVTSFNIRDTIVSTSMPGSSE 6643
Query: 2103 VNPVRQE--------IESETTSEEQI--QEEKSFESPQNSPATEQTIFDSQTFTETELKT 2152
+ + E ++ +TS++ I E+ + + ATE + + + T +
Sbjct: 6644 ITRIEMESTFSLAHGLKGTSTSQDPIVSTEKSAVLHKLTTGATETSRTEVASSRRTSIPG 6703
Query: 2153 TDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATEKSHFFLATALV 2212
D+S T S D + + +++ + + + T P + F
Sbjct: 6704 PDHS------TESPDISTEVIPSLPISLGITESSNMTIITRTGPPLGSTSQGTFTLDTPT 6757
Query: 2213 TESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELLF---------SGLGSGEEVL 2263
T S H + +T+ FP T+ D E+L + S
Sbjct: 6758 TSSRAGTHSM---------ATQEFPHSEMTTVMNKDPEILSWTIPPSIEKTSFSSSLMPS 6808
Query: 2264 PTLPTESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEG 2323
P + + V+ T + I+ T P TS + + LV TD G
Sbjct: 6809 PAMTSPPVSSTLPKTIHTTPSPMTSLLTPS--------------------LVMTTDTL-G 6847
Query: 2324 SGSVTSTTLIEILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTS--RPQTITEQD 2381
+ +T+ LS T E T + + HP T E +S Q+ D
Sbjct: 6848 TSPEPTTSSPPNLSSTSHEILTTDEDTTAIEAMHPSTSTAATNVETTSSGHGSQSSVLAD 6907
Query: 2382 SNKNSSTAEINET-----TTSSTDFLARAYGFEMAKEFVTS-APKPSDLYYEPSGEGSGE 2435
S K +TA ++ T TT ST + ++ +E S P + + S +
Sbjct: 6908 SEKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSLTPGLRETSISQNASFSTD 6967
Query: 2436 VDIV-DSFHTSATTQATRQE----SSTTFVSDGSLEKHPEVPSAKAVTADGFPTVS---- 2486
IV T T + +R E T+ PE+ + PT++
Sbjct: 6968 TSIVLSEVPTGTTAEVSRTEVTSSGRTSIPGPSQSTVLPEISTRTMTRLFASPTMTESAE 7027
Query: 2487 VMLPLHSEQNKSSPDPTSTL-SNTVSYERSTDGSFQDRFREFEDSTL------------K 2533
+ +P + + S+ T TL ++T + T + RF E +TL
Sbjct: 7028 MTIPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLMSRGPGDMSWQSS 7087
Query: 2534 PNRKKPTE-NIIIDLDKE------DKDLILTITESTILEILPELTSDKNTIIDIDHTKPV 2586
P+ + P+ ++ L L +TI+ S L + LTS T D+ HT P
Sbjct: 7088 PSLENPSSLPSLLSLPATTSPPPISSTLPVTISSSP-LPVTSLLTSSPVTTTDMLHTSP- 7145
Query: 2587 YEDILGMQTDIDTEVPSEPHDSNDE---SNDDSTQVQEIY----EAAVNLSLTEETFEGS 2639
++ T P + ++DE + D+T + ++ AA N+ + E
Sbjct: 7146 ---------ELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAASNVEIPSSGHESP 7196
Query: 2640 ADVLASYTQATHDESMTYEDRSQLDHMGFHFTTGIPAPSTETELDVLLPTATSLPIPRKS 2699
+ LA +S T + S + F T ST+ + V + T L R
Sbjct: 7197 SSALA--------DSETSKATSPM------FIT-----STQEDTTVAISTPHFLETSRIQ 7237
Query: 2700 ATVIPEIEGIKAEAKALDDMFESSTLSDGQAIADQSEIIPTLGQFERTQEEYEDKKHAGP 2759
I + + + E+S+ + A+ + I T + RT+
Sbjct: 7238 K---ESISSLSPKLRETGSSVETSSAIETSAVLSEVSIGATT-EISRTE--------VTS 7285
Query: 2760 SFQPEFSSGAEEALVDHTPYLSIATTHLMDQSVTEVPDVMEGSNPPYYTDT----TLAVS 2815
S + S AE ++ I+TT + + T P + E S T T + + S
Sbjct: 7286 SSRTSISGSAESTMLP-----EISTTRKIIKFPTS-PILAESSEMTIKTQTSPPGSTSES 7339
Query: 2816 TFAKLSSQTPSSPLTIYSGSEASGHTEI-----------PQPSALPGIDVG--------S 2856
TF +S TPS +T + ++ H+EI P+PS+LP + S
Sbjct: 7340 TFTLDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRPSSLPVEETSPPSSQLSLS 7399
Query: 2857 SVMSPQDSFKEIHVNIEATFKPSSEEYLHITEPPSLSPDTKLEPSEDDGKPELLEEMEAS 2916
+++SP + + A+ SS + P + L+ S E E S
Sbjct: 7400 AMISP----SPVSSTLPASSHSSSASVTSLLTPGQVKTTEVLDAS---------AEPETS 7446
Query: 2917 PTELIAVEGTEILQDFQNKTDGQVSGEAIKMFPTIKTPEAGTVITTADEIELEGATQWPH 2976
++ EIL + TD + K+ P T A T + T+ ++ P
Sbjct: 7447 SPPSLSSTSVEILATSEVTTDTE------KIHPFSNT--AVTKVGTSSSGHESPSSVLPD 7498
Query: 2977 STSASATYGVEAGVVPWLSPQTSERPTLSSSPEINPETQAALIRGQDSTIAASEQQVA 3034
S + AT + + + ++ P LS++ +I E ++L T + E +A
Sbjct: 7499 SETTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASSLTTRLRETSTSEETSLA 7556
Score = 118 bits (295), Expect = 1e-25
Identities = 603/2999 (20%), Positives = 1034/2999 (34%), Gaps = 506/2999 (16%)
Query: 357 SILAETASPSLSKEPQMVSDRTTPIIPLVDELPVIPTEFPPVGNIVSFEQKATVQPQAIT 416
S A T++P + PQ ++ T I P +LP +G+I S V P A+
Sbjct: 3746 SATATTSAPQGATTPQELTLETM-ISPATSQLPF------SIGHITS-----AVTPAAMA 3793
Query: 417 DSLATKLPTPTGSTKKPWDMDDYSPSASGP------------------LGKLDISEIKEE 458
S P ++KK P+ + K + + +
Sbjct: 3794 RSSGVTFSRPDPTSKKAEQTSTQLPTTTSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQ 3853
Query: 459 VLQSTTGVSHYATDSWDGVVEDKQTQ------ESVTQIEQIEVGPLVTSMEILKHIPSKE 512
+ T + +DSW+ ++K T E + + + + + +S +L+ + + +
Sbjct: 3854 GQTALTTEARATSDSWNE--KEKSTPSAPWITEMMNSVSEDTIKEVTSSSSVLRTLNTLD 3911
Query: 513 FPV----TETPLVTARMI-----LESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLT 563
+ T +P + ES T+K+ + + V T G+ E T+
Sbjct: 3912 INLESGTTSSPSWKSSPYERIAPSESTTDKEAIHPSTNTVETT--GWVTSSEHASHSTIP 3969
Query: 564 VGSDESTLIFDQIPE------VITVSKTS--EDT---------IHTHLEDLE---SVSAS 603
S S L + ++++S T+ E T + L D+ S++
Sbjct: 3970 AHSASSKLTSPVVTTSTREQAIVSMSTTTWPESTRARTEPNSFLTIELRDVSPYMDTSST 4029
Query: 604 TTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGKYLSTTPFPSQHRTEIELFP---YSG 660
T S + P + + E +S RI+ FL + + ++ PS+ T + FP SG
Sbjct: 4030 TQTSIISSPGSTAITKGPRTEITSSKRISSSFLAQSMRSSDSPSEAITRLSNFPAMTESG 4089
Query: 661 DKILV-----EGISTVIYPSLQTEMTHRRERTETLIPEMRTDTYTDEIQ-----EEITKS 710
IL G +++ P+L T T T T + + TY+++ E T
Sbjct: 4090 GMILAMQTSPPGATSLSAPTLDTSAT--ASWTGTPLATTQRFTYSEKTTLFSKGPEDTSQ 4147
Query: 711 PFMGKTEEEVFSGMKLSTSLSEPIHVTESS----------------------VEMTKSFD 748
P EE S+S PIH T S + T
Sbjct: 4148 PSPPSVEE------TSSSSSLVPIHATTSPSNILLTSQGHSPSSTPPVTSVFLSETSGLG 4201
Query: 749 FPTLITKLSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHG---TLSVEAATVSKWSW 805
T ++++S EP TA + Y+ + T + H ++ AT S++S
Sbjct: 4202 KTTDMSRISLEPGTSLPPNLSSTAGEALSTYEASRDTKAIHHSADTAVTNMEATSSEYSP 4261
Query: 806 DEDNTTSKPLESTEPSASSKLPPALLTTVGMNGKDKDIPSFT---------EDGADEFTL 856
+T KP ++T P +S + + ++ + G + T E +
Sbjct: 4262 IPGHT--KPSKATSPLVTSHIMGDITSSTSVFGSSETTEIETVSSVNQGLQERSTSQVAS 4319
Query: 857 IPDSTQKQLEEVTDEDIAAHGKFTIRFQPTTSTG---------IAEKSTLRDSTTEEKVP 907
T + V+ D H + Q T S+G I +T D +T
Sbjct: 4320 SATETSTVITHVSSGDATTH---VTKTQATFSSGTSISSPHQFITSTNTFTDVSTNPSTS 4376
Query: 908 PITSTEGQVYATMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYV 967
I + V T + G ST+P T LA E TT +
Sbjct: 4377 LIMTESSGVTITTQTGPTGAATQGPYLLDTSTMPYLTETP----LAVTPDFMQSEKTTLI 4432
Query: 968 -----DSSHTIPLSV----IPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEATISP 1018
D S T P SV P + LV ++P L Q + ++
Sbjct: 4433 SKGPKDVSWTSPPSVAETSYPSSLTPFLVTTIPPATSTL----QGQHTSSPVSATSVLTS 4488
Query: 1019 ETMRTTKITEGTTQEEFPWKEQTAEKPVPALSST--AWTPKEAVTPLDEQE----GDGSA 1072
++TT + T+ E Q P + +T A T E + P + G S+
Sbjct: 4489 GLVKTTDML-NTSMEPVTNSPQNLNNPSNEILATLAATTDIETIHPSINKAVTNMGTASS 4547
Query: 1073 YTVSEDELLTGSE----RVPVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGP 1128
V L SE P++ + +G S+S P T+ + + P
Sbjct: 4548 AHVLHSTLPVSSEPSTATSPMVPASSMGDALASISIPGSETTDIEGE------------P 4595
Query: 1129 KVSLSPG-PEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEK 1187
SL+ G E E +STT LS S + + E T E S + +
Sbjct: 4596 TSSLTAGRKENSTLQEMNSTTESNIILSNVS--VGAITEATKMEVPSFDATFI------- 4646
Query: 1188 PKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKKPPL-IDREPGEETTS 1246
P + +F I S ++ + H T+ SS T K PL +D E +
Sbjct: 4647 PTPAQSTKFPDIFSVASSRLSNSPPMTISTHMTTTQTGSSGATSKIPLALDTSTLETSAG 4706
Query: 1247 DMVIIGESTSHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQA 1306
++ E +H TT + K+ SSP + P T+ AF PQ
Sbjct: 4707 TPSVVTEGFAHSKITTAMNNDVKDVSQTNPPFQDEASSPSSQAPVLVTTLPSSVAFTPQW 4766
Query: 1307 LSTPQPPASTKFHPDINVYIIEVRENKTGRMSDLS---VIGHPIDSESKEDE-----PCS 1358
ST P + + ++ KT D S V P + D+ +
Sbjct: 4767 HSTSSPVSMSS--------VLTSSLVKTAGKVDTSLETVTSSPQSMSNTLDDISVTSAAT 4818
Query: 1359 EETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVT 1418
+ + H + ++ HS + E + +VTT+ + +
Sbjct: 4819 TDIETTHPSINTVVTNVGTTGSAFESHSTVSAYPEPSKVTSPNVTTST----MEDTTISR 4874
Query: 1419 TVPKDPEAAEARRGQFESVAP-------SQNFSDSSESDTHPFVIAKTELSTAVQPNEST 1471
++PK + S+ P SQ + S+E+ T P+ EL+ A T
Sbjct: 4875 SIPKSSKTTRTETETTSSLTPKLRETSISQEITSSTETSTVPY----KELTGATTEVSRT 4930
Query: 1472 ETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTER-----D 1526
+ T S +S F G PD TV E+ T + +TE
Sbjct: 4931 DVTSS------------SSTSFPG--PDQ-STVSLDISTETNTRLSTSPIMTESAEITIT 4975
Query: 1527 TEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTI 1586
T+ G + ++ P ++ + I + F++ T + + S T P++
Sbjct: 4976 TQTGPHGATSQDTFTMDPSNTTPQAGI-HSAMTHGFSQLDVTTLMSRIPQDVSWTSPPSV 5034
Query: 1587 -VPSSASAYVSEEEAVT--LIGNPWPDDLLST-KESWVEATPRQVVELSGSSSIPITEGS 1642
SS S+++S T LI + P+D LS+ S + + ++ ++ + P+T
Sbjct: 5035 DKTSSPSSFLSSPAMTTPSLISSTLPEDKLSSPMTSLLTSGLVKITDILRTRLEPVTSSL 5094
Query: 1643 GEAEEDEDTMFTMVTDLSQR-------NTTDTLITLD--------------------TSR 1675
D + D NT +T + + T
Sbjct: 5095 PNFSSTSDKILATSKDSKDTKEIFPSINTEETNVKANNSGHESHSPALADSETPKATTQM 5154
Query: 1676 IITESFFEVPATTIYPV---SEQPSAKVVPTKFVS----ETDTSEWIS-STTVEEKKRKE 1727
+IT + + +T PV SE + K PT F++ ET TS+ S T K
Sbjct: 5155 VITTTVGDPAPSTSMPVHGSSETTNIKREPTYFLTPRLRETSTSQESSFPTDTSFLLSKV 5214
Query: 1728 EEGTTGTASTFEVYSSTQRS----DQLILP---FELESPNVATSSDSGTRKSFMSLTTPT 1780
GT S+ V SS++ S D+ +P F E P V TSS T+ + M++TT
Sbjct: 5215 PTGTITEVSSTGVNSSSKISTPDHDKSTVPPDTFTGEIPRVFTSSIK-TKSAEMTITTQA 5273
Query: 1781 QSEREMTDSTPVFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEA 1840
+ ST + TL G HS++ Q P S + M G G
Sbjct: 5274 SPPESASHSTLPLDTSTTLSQGGT----HSTVTQ--------GFPYSEVTTLMGMGPGNV 5321
Query: 1841 A---ADPETTTVSSFSLNVEYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAE 1897
+ P T S SL A+ + V+ ST P + S + +
Sbjct: 5322 SWMTTPPVEETSSVSSLMSSPAMTSPSPVS-----------STSPQSIPSSPLPVTALPT 5370
Query: 1898 NITQTSREIVISERLGEPNYGAEIRGFSTGFPLEEDFSGDFREYSTVSH--PIAKEETVM 1955
++ T+ +++ G E + S+++H P ++T
Sbjct: 5371 SVLVTTTDVL-------------------GTTSPESVTSSPPNLSSITHERPATYKDTAH 5411
Query: 1956 MEGSGDAAFRDTQTSPSTVPTS-----VHISHISDSEGPSST-MVSTSAFPWEEFTSSAE 2009
E A T T+ + V TS S ++DSE +T ++ST++ + S++
Sbjct: 5412 TEA---AMHHSTNTAVTNVGTSGSGHKSQSSVLADSETSKATPLMSTTSTLGDTSVSTST 5468
Query: 2010 GSGEQLVTV----SSSVVPVL--PSAVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPT 2063
+ Q + ++S+ P L S +K S T + G + + R
Sbjct: 5469 PNISQTNQIQTEPTASLSPRLRESSTSEKTSSTTETNTAFSYVPTGAITQASRTEISSSR 5528
Query: 2064 AEVEGTKAPVEKEEVKVSGTVSTNFPQTIEPAKLWSRQEVNPVRQEIESETTSEEQIQEE 2123
+ P ++ +G ++ F I + E+ Q TS+ + +
Sbjct: 5529 TSISDLDRPTIAPDIS-TGMITRLFTSPI----MTKSAEMTVTTQTTTPGATSQGILPWD 5583
Query: 2124 KSFESPQNSPATEQTIFDSQTFTETELKTT------DYSVLTTKKTYSDDKEMKEEDTSL 2177
S Q T T+ SQ F +E+ T D S +TT E SL
Sbjct: 5584 TSTTLFQG--GTHSTV--SQGFPHSEITTLRSRTPGDVSWMTTPPV-----EETSSGFSL 5634
Query: 2178 VNMSTPDPDANGLESYTTLPEATEKSHFFLATALVTES----IPAEHVVTDSPIKKEEST 2233
++ S P S ++P + L + LVT + + VT SP T
Sbjct: 5635 MSPSMTSPSPVSSTSPESIPSSPLPVTALLTSVLVTTTNVLGTTSPEPVTSSPPNLSSPT 5694
Query: 2234 KHFPKGMRPTIQ------ESDTELLFSGLG---SGEEVLPTLPTESVNFTEVEQINNTLY 2284
+ + T T + +G SG E ++P +S + T
Sbjct: 5695 QERLTTYKDTAHTEAMHASMHTNTAVANVGTSISGHESQSSVPADSHTSKATSPMGITFA 5754
Query: 2285 PHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVTSTTLIEILSDTGAEGP 2344
+ V +++ E + E+ + + P + T E +VT T+ +LS+
Sbjct: 5755 MGDTSVSTSTPAFFETRIQTESTSSLI-PGLRDTRTSEEINTVTETS--TVLSE------ 5805
Query: 2345 TVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSNKNSSTAEINETTTSSTDFLAR 2404
P +T++ E+ TS TI+ D +K S ET T + F
Sbjct: 5806 --VPTTTTTEVSR---------TEVITSSRTTISGPDHSKMSPYIS-TETITRLSTFPFV 5853
Query: 2405 AYGFEMAKE-------FVTSAPKPSDLYYEPSGEGSGEVDIVDSFHTSATTQATRQESST 2457
EMA ++ A D S EG+ H+ TT +R
Sbjct: 5854 TGSTEMAITNQTGPIGTISQATLTLDTSSTASWEGTHSPVTQRFPHSEETTTMSRSTKGV 5913
Query: 2458 TFVSDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSEQNKSSPDPTSTLSNTVSYERSTD 2517
++ S S+E+ PS+ P ++ L+S + SSP +++ ++ R
Sbjct: 5914 SWQSPPSVEE-TSSPSSPV----PLPAITSHSSLYSAVSGSSPTSALPVTSLLTSGRRKT 5968
Query: 2518 GSFQDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDLILTITESTILEILPELTSDKNTI 2577
D E S+L P+ + I+ + + I +E+T + S
Sbjct: 5969 IDMLDTHSELVTSSL-PSASSFSGEILTSEASTNTETI-HFSENTAETNMGTTNSMHKLH 6026
Query: 2578 IDID-------HTKPVYEDILGMQTDIDTEVPSEPHDSNDESNDDSTQVQEIYE---AAV 2627
+ HT P + + T P P N + + S E+ E A V
Sbjct: 6027 SSVSIHSQPSGHTPPKVTGSMMEDAIVSTSTPGSPETKNVDRDSTSPLTPELKEDSTALV 6086
Query: 2628 NLSLTEETFEGSADVLASYTQATHDESMTYEDRSQLDHMGFHFTTGIPAPSTETELDVLL 2687
S TE S+ L + T+ + E +TY D T +PA + T+ +
Sbjct: 6087 MNSTTESNTVFSSVSLDAATEVSRAE-VTYYD-----------PTFMPASAQSTKSPDIS 6134
Query: 2688 PTATSLPIPRKSATVIPEIEGIKAEAKALDDMFESSTLSDGQAIADQSEIIPTLG-QFER 2746
P A+S S + P + I S S GQ D S I + G R
Sbjct: 6135 PEASS------SHSNSPPLT-ISTHKTIATQTGPSGVTSLGQLTLDTSTIATSAGTPSAR 6187
Query: 2747 TQE------------EYEDKKHAGPSFQPEFSSGAEEALVDHTPYLSIATTHLMDQSVTE 2794
TQ+ + D P E +S + +A + T S T+ L + S +
Sbjct: 6188 TQDFVDSETTSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSS 6247
Query: 2795 VPDVMEGSNPPYYTDTTLAVSTFAKLSSQTPSSPLTIYSGSEASGHTEIPQPSALPGIDV 2854
+ V P T + T + +++P + + SEA+ T PS +
Sbjct: 6248 LVSVTSVPTPTLAKITDM--DTNLEPVTRSPQNLRNTLATSEATTDTHTMHPSINTAVAN 6305
Query: 2855 GSSVMSPQDSFKEIHVNIEATFKPSSEEYLHITEP--PSLSPDTKLEPSEDDGKPELLEE 2912
+ SP + + T P S+ Y + S S D+ + S E
Sbjct: 6306 VGTTSSPNEFY--------FTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMKKIE 6357
Query: 2913 MEASPTELIAVEGTEILQDFQNKTDGQVSGEAIKMFPTIKTPEAGTVITTADEIELEGAT 2972
E + + + + T Q + +D S K F T + T +T++ ++G
Sbjct: 6358 SETTFSLIFRLRETSTSQKIGSSSD--TSTVFDKAFTAATTEVSRTELTSSSRTSIQGTE 6415
Query: 2973 QWPHSTSASATYGVEAGVVPWLSPQTSERPTLSSSPEINPETQAALIRGQDSTIAAS--- 3029
+ P +SP TS R S T A L + ++ TIA
Sbjct: 6416 K------------------PTMSPDTSTRSVTMLS------TFAGLTKSEERTIATQTGP 6451
Query: 3030 EQQVAARILDSNDQATVNPVEFNTEVATPPFSLLE----TSNETDFLIGINEESVEGTA 3084
+ + L + T + ++ + T FS L+ TS +++ G + SVE T+
Sbjct: 6452 HRATSQGTLTWDTSITTSQAGTHSAM-THGFSQLDLSTLTSRVPEYISGTSPPSVEKTS 6509
Score = 106 bits (264), Expect = 4e-22
Identities = 654/3136 (20%), Positives = 1076/3136 (34%), Gaps = 640/3136 (20%)
Query: 346 FKPKEATTIDLSILAETASPSLSKEPQMVSDRTTPI--IPLVDELPVIPTE-FPPVGNIV 402
F+ + T S++ S+E V++ +T + +P V TE +
Sbjct: 5768 FETRIQTESTSSLIPGLRDTRTSEEINTVTETSTVLSEVPTTTTTEVSRTEVITSSRTTI 5827
Query: 403 SFEQKATVQPQAITDSLA--TKLPTPTGSTKKPWDMDDYSPSASGPLGKLDISEIKEEVL 460
S + + P T+++ + P TGST+ + +GP+G +
Sbjct: 5828 SGPDHSKMSPYISTETITRLSTFPFVTGSTEMA------ITNQTGPIGTIS--------- 5872
Query: 461 QSTTGVSHYATDSWDG----VVEDKQTQESVTQIEQIEVGPLVTSMEILKHIPSKEFPVT 516
Q+T + +T SW+G V + E T + + G S ++ S PV
Sbjct: 5873 QATLTLDTSSTASWEGTHSPVTQRFPHSEETTTMSRSTKGVSWQSPPSVEETSSPSSPVP 5932
Query: 517 ETPLVTARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQI 576
P +T+ L S S S L T LT G ++ + D
Sbjct: 5933 -LPAITSHSSLYSAVSGS--SPTSALPVTS--------------LLTSGRRKTIDMLDTH 5975
Query: 577 PEVITVSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFL 636
E++T S S + + E AST + +N E + L
Sbjct: 5976 SELVTSSLPSASSFSGEILTSE---ASTNTETIHFSENTA-------ETNMGTTNSMHKL 6025
Query: 637 GKYLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRERTETLIPEMRT 696
+S PS H P ++ + I + P R+ T L PE++
Sbjct: 6026 HSSVSIHSQPSGHTP-----PKVTGSMMEDAIVSTSTPGSPETKNVDRDSTSPLTPELKE 6080
Query: 697 DTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMTKSFDFPTLITKL 756
D+ T + T+S VFS + L + TE S +D PT +
Sbjct: 6081 DS-TALVMNSTTES-------NTVFSSVSLDAA-------TEVSRAEVTYYD-PTFMPA- 6123
Query: 757 SAEPTEVRDMEEDFTAT-----PGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNTT 811
SA+ T+ D+ + +++ P T + I T G S+ T+ +T+
Sbjct: 6124 SAQSTKSPDISPEASSSHSNSPPLTISTHKTIATQTGPSGVTSLGQLTL--------DTS 6175
Query: 812 SKPLESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDE 871
+ + PSA ++ TT MN D+ + A+E + S+Q L T
Sbjct: 6176 TIATSAGTPSARTQDFVDSETTSVMNNDLNDVLKTSPFSAEEANSL--SSQAPLLVTTSP 6233
Query: 872 DIAAHGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDV 931
P TST ++ S T P L ++ D+
Sbjct: 6234 S------------PVTSTLQEHSTSSLVSVTSVPTP----------------TLAKITDM 6265
Query: 932 DLS-KPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSV 990
D + +PV+ PQ + +T E TT +HT+ S+ V S
Sbjct: 6266 DTNLEPVTRSPQNLRNT----------LATSEATT---DTHTMHPSINTAVA-NVGTTSS 6311
Query: 991 PSEDEVLGEPSQD------ILVIDQTRLEATISPETMRTTKI----TEGTTQEEFPWKEQ 1040
P+E P D +VI T ++ +S R++ + +E T F +E
Sbjct: 6312 PNEFYFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMKKIESETTFSLIFRLRET 6371
Query: 1041 TAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETT-PVGKID 1099
+ + + + S T+ +A T + VS EL T S R + T P D
Sbjct: 6372 STSQKIGSSSDTSTVFDKAFTAATTE--------VSRTEL-TSSSRTSIQGTEKPTMSPD 6422
Query: 1100 HSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGP--------EQKYETEGSSTTGFT 1151
S T + E T+ + GP + S G + T + T GF+
Sbjct: 6423 TSTRSVTMLSTFAGLTKSEERTIATQTGPHRATSQGTLTWDTSITTSQAGTHSAMTHGFS 6482
Query: 1152 S-SLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDITTA 1210
LS ++ + + + T+ S+E S L P T S + T+P ++
Sbjct: 6483 QLDLSTLTSRVPEYISGTSPP--SVEKTSSSSSLLSLPAITSP---SPVPTTLPESRPSS 6537
Query: 1211 FSSVDRLHTTSAFKPS---SAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIV 1267
+ L T+ K + +++ PP + STSH PTT EDI
Sbjct: 6538 PVHLTSLPTSGLVKTTDMLASVASLPPNLG----------------STSHKIPTTSEDI- 6580
Query: 1268 AKETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYII 1327
D ++ Y +T+ T T +KE++ + P ++ N+
Sbjct: 6581 -----KDTEKMYPSTNIAVTNVGT---TTSEKESYSSVPAYSEPPKVTSPMVTSFNIRDT 6632
Query: 1328 EVRENKTG-------RMSDLSVIGHPIDSESKEDEP--CSEETDPVH------------- 1365
V + G M + H + S +P +E++ +H
Sbjct: 6633 IVSTSMPGSSEITRIEMESTFSLAHGLKGTSTSQDPIVSTEKSAVLHKLTTGATETSRTE 6692
Query: 1366 -------------------DLMAEILPEFPDIIEI----DLYHSEENEEEEEECANATDV 1402
D+ E++P P + I ++ + T
Sbjct: 6693 VASSRRTSIPGPDHSTESPDISTEVIPSLPISLGITESSNMTIITRTGPPLGSTSQGTFT 6752
Query: 1403 TTTPSVQYINGKH-----------LVTTVPKDPEAAE-------ARRGQFESVAPSQNFS 1444
TP+ G H + T + KDPE + S+ PS +
Sbjct: 6753 LDTPTTSSRAGTHSMATQEFPHSEMTTVMNKDPEILSWTIPPSIEKTSFSSSLMPSPAMT 6812
Query: 1445 DSSESDTHPFVIAKTE------LSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEP 1498
S T P I T L+ ++ T T T P TS +
Sbjct: 6813 SPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEPTTSSPPNLSSTSHEILTTDE 6872
Query: 1499 DVFPTVPFH-------EEFESGTAKKGAESVTERDTE-------------VGHQAHEHTE 1538
D H E+ ++ G++S D+E +GH
Sbjct: 6873 DTTAIEAMHPSTSTAATNVETTSSGHGSQSSVLADSEKTKATAPMDTTSTMGHTT----- 6927
Query: 1539 PVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSASAYVSEE 1598
VS SS I +ES E + + ST + + VP+ +A VS
Sbjct: 6928 -VSTSMSVSSETTKIKRESTYSLTPGLRETSISQNASFSTDTSIVLSEVPTGTTAEVSRT 6986
Query: 1599 EAV----TLIGNPWPDDLLS--TKESWVEATPRQVVELSGSSSIPITEG-SGEAEEDEDT 1651
E T I P +L + + + S +IP G SG +D T
Sbjct: 6987 EVTSSGRTSIPGPSQSTVLPEISTRTMTRLFASPTMTESAEMTIPTQTGPSGSTSQDTLT 7046
Query: 1652 MFTMVTDLSQRNTTDTL--------ITLDTSR----------------IITESFFEVPAT 1687
+ T T SQ T TL +T SR S +PAT
Sbjct: 7047 LDTSTTK-SQAKTHSTLTQRFPHSEMTTLMSRGPGDMSWQSSPSLENPSSLPSLLSLPAT 7105
Query: 1688 TIYP-----------VSEQPSAKVVPTKFVSETD----TSEWISSTTVEEKKRKEEEGTT 1732
T P S P ++ + V+ TD + E ++S+ + +E TT
Sbjct: 7106 TSPPPISSTLPVTISSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTT 7165
Query: 1733 G--TASTFEVYSSTQ--RSDQLILPFELESPNVATSSDSGTRKSFMSLTTPTQSEREMTD 1788
G T +T V+ ST S+ I ESP+ A + ++ + T TQ + +
Sbjct: 7166 GKDTTNTEAVHPSTNTAASNVEIPSSGHESPSSALADSETSKATSPMFITSTQEDTTVAI 7225
Query: 1789 STPVFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLPRSPA---SVFMEQGSGEAAADPE 1845
STP F ET+ ++ E S P ++E +++ S A S + + S A +
Sbjct: 7226 STPHFLETSRIQK------ESISSLSPKLRETGSSVETSSAIETSAVLSEVSIGATTEIS 7279
Query: 1846 TTTVSSFSLNVEYAIQAEKEVAGTLSPHVETT-----FSTEPTGLVLSTVMDRVVAENIT 1900
T V+S S +I E T+ P + TT F T P ++AE
Sbjct: 7280 RTEVTSSS---RTSISGSAE--STMLPEISTTRKIIKFPTSP-----------ILAE--- 7320
Query: 1901 QTSREIVISERLGEPNYGAEIRGFSTGFPLEEDFSGDF-REYSTVSHPIAKEE--TVMME 1957
S E+ I + P +E + F L+ + +ST++ + E T++
Sbjct: 7321 --SSEMTIKTQTSPPGSTSE-----STFTLDTSTTPSLVITHSTMTQRLPHSEITTLVSR 7373
Query: 1958 GSGD----AAFRDTQTSP-----------------STVPTSVHISHISDSEGPSSTMVST 1996
G+GD ++ +TSP ST+P S H S S + + V T
Sbjct: 7374 GAGDVPRPSSLPVEETSPPSSQLSLSAMISPSPVSSTLPASSHSSSASVTSLLTPGQVKT 7433
Query: 1997 SAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSA--------VQKFSGTASSIIDEGLGEV 2048
+ E +SAE ++SS+ V +L ++ + FS TA + +V
Sbjct: 7434 T----EVLDASAEPETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTA-------VTKV 7482
Query: 2049 GTVNE-IDRRSTILPTAEVEGTKAPVEKEEVKVSG--TVSTNFPQTIEPAKLWSRQEVNP 2105
GT + + S++LP +E TKA + + G +VST P K+ S +
Sbjct: 7483 GTSSSGHESPSSVLPDSET--TKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASSL 7540
Query: 2106 VRQEIESETTSEEQIQEEKS--FESPQNSPATEQTIFDSQTFTETELKTTDYSVLT---- 2159
+ E+ T+ E + E + TE + ++ +F+ T + + S ++
Sbjct: 7541 TTRLRETSTSEETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTMSQDIS 7600
Query: 2160 --TKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATEKSHFFLATALVTESIP 2217
T S + E + T P + LES L AT S + ++V + P
Sbjct: 7601 IGTIPRISASSVLTESAKMTITTQT-GPSESTLESTLNLNTATTPS-WVETHSIVIQGFP 7658
Query: 2218 AEHVVT------------DSPIKKEESTKHFPKGMR----------------PTIQESDT 2249
+ T P KE S P + P T
Sbjct: 7659 HPEMTTSMGRGPGGVSWPSPPFVKETSPPSSPLSLPAVTSPHPVSTTFLAHIPPSPLPVT 7718
Query: 2250 ELLFSGLGSGEEVL------PTLPTESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNR 2303
LL SG + ++L T + S++ T E++ T Y T+ E+
Sbjct: 7719 SLLTSGPATTTDILGTSTEPGTSSSSSLSTTSHERL--TTYKDTAHTEAVHPSTNTGGT- 7775
Query: 2304 MENVAKEVGPLVSQTDIFEGSGSVTSTTLIEILSDTGAEGPTVAPLPFSTDIGHPQNQTV 2363
NVA SQ+ + S + +T+ + DT T A L +T
Sbjct: 7776 --NVATTSSGYKSQSSVLADSSPMCTTS---TMGDTSVLTSTPAFL-----------ETR 7819
Query: 2364 RWAEEIQTSRPQTITEQDSNKNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPSD 2423
R E+ +S + E ++ +S+ T S A E++KE VTS P P+
Sbjct: 7820 RIQTELASSLTPGLRESSGSEGTSSGTKMSTVLSKVPTGATT---EISKEDVTSIPGPAQ 7876
Query: 2424 ------------LYYEPSGEGSGEVDIVDSFHTS---ATTQ--ATRQESSTT--FVSDGS 2464
++ S + +I + HTS ATTQ +T SSTT ++ +
Sbjct: 7877 STISPDISTRTVSWFSTSPVMTESAEITMNTHTSPLGATTQGTSTLDTSSTTSLTMTHST 7936
Query: 2465 LEKHPEVPSAKAVTADGFPTVSVMLP-----------LHSEQNKSSPDP-TSTLSNTVSY 2512
+ + + G VS M P L S +SP P +STL ++S
Sbjct: 7937 ISQGFSHSQMSTLMRRGPEDVSWMSPPLLEKTRPSFSLMSSPATTSPSPVSSTLPESISS 7996
Query: 2513 ERSTDGSFQDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDLILTITESTILEILPELTS 2572
S + + + +P N +L +++ T +T E S
Sbjct: 7997 SPLPVTSLLTSGLA-KTTDMLHKSSEPVTNSPANLSSTSVEILATSEVTTDTE--KTHPS 8053
Query: 2573 DKNTIIDIDHTKPVYEDILGMQTDIDTEVPSEPH--DSNDESNDDSTQVQEIYE------ 2624
T+ D+ + +E + D T + P S E ST +E
Sbjct: 8054 SNRTVTDVGTSSSGHESTSFVLADSQTSKVTSPMVITSTMEDTSVSTSTPGFFETSRIQT 8113
Query: 2625 ---AAVNLSL--------TEETFEGSADVLASYTQATHDESMT-YEDRSQLDHMGFHFTT 2672
+++ L L T E S + T AT + S T S+ GF T
Sbjct: 8114 EPTSSLTLGLRKTSSSEGTSLATEMSTVLSGVPTGATAEVSRTEVTSSSRTSISGFAQLT 8173
Query: 2673 GIPAPSTETELDVLLPTATSLPIPRKSATVIPEIEGIKAEAKALDDMFESSTLSDGQAIA 2732
+P T TE LPT++ I +SA ++ IK + ES+ D
Sbjct: 8174 --VSPETSTETITRLPTSS---IMTESAEMM-----IKTQTDPPGSTPESTHTVDISTTP 8223
Query: 2733 DQSEIIPTLGQ-FERTQEEYEDKKHAGPSFQPEFSSGAE--------------------E 2771
+ E T+ Q F ++ + G P SS E
Sbjct: 8224 NWVETHSTVTQRFSHSEMTTLVSRSPGDMLWPSQSSVEETSSASSLLSLPATTSPSPVSS 8283
Query: 2772 ALVDHTPYLSIATTHLMDQSVTEVPDVMEGSNPPYYTDTTLAVSTFAKLSSQTPSSPLTI 2831
LV+ P S+ T L++ + D M S P + T+ ST + + + T
Sbjct: 8284 TLVEDFPSASLPVTSLLNPGLVITTDRMGISREPGTSSTSNLSSTSHERLTTLEDTVDT- 8342
Query: 2832 YSGSEASGHTEIPQ-PSALPGIDVGSSVMSPQDSFK------------EIHVNIEA---- 2874
+ S HT + +++ G + SSV+S ++ K E V+I
Sbjct: 8343 -EDMQPSTHTAVTNVRTSISGHESQSSVLSDSETPKATSPMGTTYTMGETSVSISTSDFF 8401
Query: 2875 -TFKPSSEEYLHITEPPSLSPDTKLEPSEDDGKPELLE-----EMEASPTELIAVEGTEI 2928
T + E +T + ++ S +G L E E S TE+I+ GT +
Sbjct: 8402 ETSRIQIEPTSSLTSGLRETSSSERISSATEGSTVLSEVPSGATTEVSRTEVISSRGTSM 8461
Query: 2929 LQDFQNKTDGQVSGEAIKMFPT--IKTPEAGTVITTAD-----------EIELEGATQW- 2974
Q +S EAI T I T A + IT ++ T W
Sbjct: 8462 SGPDQFTISPDISTEAITRLSTSPIMTESAESAITIETGSPGATSEGTLTLDTSTTTFWS 8521
Query: 2975 -PHSTSASATYGVE--------AGVVPWLS-PQTSERPTLSSSPEINPETQAALIRGQDS 3024
HST++ E G VPW S P E ++SSS T +
Sbjct: 8522 GTHSTASPGFSHSEMTTLMSRTPGDVPWPSLPSVEEASSVSSSLSSPAMTSTSFFSTLPE 8581
Query: 3025 TIAASEQQVAARILDSNDQATVNPVEFNTEVATPPFSLLETSNETDFLIGINEESVEGTA 3084
+I++S V A + T+ PV+ + T + ET ++ S E A
Sbjct: 8582 SISSSPHPVTALL-------TLGPVKTTDMLRT------SSEPETSSPPNLSSTSAEILA 8628
Query: 3085 IYLPGPDRCKMNPCLN 3100
DR K++P N
Sbjct: 8629 TSEVTKDREKIHPSSN 8644
Score = 103 bits (257), Expect = 3e-21
Identities = 554/2725 (20%), Positives = 943/2725 (34%), Gaps = 462/2725 (16%)
Query: 407 KATVQPQAITDSLATKLPTPTGSTKKPWDMDDYSPSASGPLGK-------LDISEIKEEV 459
++TV P+ T ++ +PT + + P+ +GP G LD S K +
Sbjct: 7001 QSTVLPEISTRTMTRLFASPTMTESAEMTI----PTQTGPSGSTSQDTLTLDTSTTKSQA 7056
Query: 460 L------------QSTTGVSHYATD-SWDGV--VEDKQTQESVTQIEQIEVGPLVTSMEI 504
+ TT +S D SW +E+ + S+ + P ++S +
Sbjct: 7057 KTHSTLTQRFPHSEMTTLMSRGPGDMSWQSSPSLENPSSLPSLLSLPATTSPPPISST-L 7115
Query: 505 LKHIPSKEFPVTE----TPLVTARMI-----LESKTEKKMVSTVSELVTTGHYGFTLGEE 555
I S PVT +P+ T M+ L + + K+ T E +TTG
Sbjct: 7116 PVTISSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTG--------- 7166
Query: 556 DDEDRTLTVGSDESTLIFDQIPEVITVSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNN 615
+D T T ST + + + + ++ + L D E+ S SP+ +
Sbjct: 7167 --KDTTNTEAVHPST---NTAASNVEIPSSGHESPSSALADSET---SKATSPMFITS-- 7216
Query: 616 GSSMDDWEERQTSGRITEEFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPS 675
T+E +ST F R + E K+ G S +
Sbjct: 7217 ----------------TQEDTTVAISTPHFLETSRIQKESISSLSPKLRETGSSVETSSA 7260
Query: 676 LQTEMTHRRERTETLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIH 735
++ T ++ E+ T+ + E+T S SG ST L E I
Sbjct: 7261 IE---------TSAVLSEVSIGATTEISRTEVTSS------SRTSISGSAESTMLPE-IS 7304
Query: 736 VTESSVEMTKSFDFPTLITKLSAEPTEVRDMEEDFTATPGTTK-----YDENIT-TVLLA 789
T K FPT + + AE +E+ + T+ PG+T D + T ++++
Sbjct: 7305 TTR------KIIKFPT--SPILAESSEMTIKTQ--TSPPGSTSESTFTLDTSTTPSLVIT 7354
Query: 790 HGTL------SVEAATVSKWSWDEDNTTSKPLESTEPSASSKLPPALLTTVGMNGKDKDI 843
H T+ S VS+ + D +S P+E T P +S +L + + +
Sbjct: 7355 HSTMTQRLPHSEITTLVSRGAGDVPRPSSLPVEETSPPSSQL---SLSAMISPSPVSSTL 7411
Query: 844 PSFTEDGADEFTLIPDSTQKQLEEVTDEDIAAHGKFTIRFQPTTSTGIAEKSTLRDSTTE 903
P+ + + T + Q + EV D A+ T +ST + +T +T
Sbjct: 7412 PASSHSSSASVTSLLTPGQVKTTEVLD---ASAEPETSSPPSLSSTSVEILATSEVTTDT 7468
Query: 904 EKVPPITSTEGQVYATMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSSTQEP 963
EK+ P ++T T G++ E P S +P T + +S
Sbjct: 7469 EKIHPFSNTA----VTKVGTSSSGHE-----SPSSVLPDSETTKATSAMGTISIMGDTSV 7519
Query: 964 TTYVDS-SHTIPLSVIPKTDWGV-LVPSVPSEDEVLGEPSQDILVIDQTRLEATISPETM 1021
+T + S+T + P + L + SE+ L + +L +++ + E
Sbjct: 7520 STLTPALSNTRKIQSEPASSLTTRLRETSTSEETSLATEANTVL----SKVSTGATTEVS 7575
Query: 1022 RTTKITEGTTQ----EEFPWKEQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSE 1077
RT I+ T E+ + + +P +S+++ + A + Q G + S
Sbjct: 7576 RTEAISFSRTSMSGPEQSTMSQDISIGTIPRISASSVLTESAKMTITTQTGPSESTLEST 7635
Query: 1078 DELLTGS------------ERVPVLE-TTPVGKIDHSVSYP-----------------PG 1107
L T + + P E TT +G+ VS+P P
Sbjct: 7636 LNLNTATTPSWVETHSIVIQGFPHPEMTTSMGRGPGGVSWPSPPFVKETSPPSSPLSLPA 7695
Query: 1108 AVTEHKVKTDEVVTLTPRIGPKVS-LSPGPEQKYETEGSSTTGFTSSLSPFST------- 1159
+ H V T + + P P S L+ GP + G+ST TSS S ST
Sbjct: 7696 VTSPHPVSTTFLAHIPPSPLPVTSLLTSGPATTTDILGTSTEPGTSSSSSLSTTSHERLT 7755
Query: 1160 ------HITQLMEETTTEKTSLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDITTAFSS 1213
H + T T T++ G K +++ L + S + T T+ +S
Sbjct: 7756 TYKDTAHTEAVHPSTNTGGTNVATTSSG----YKSQSSVLADSSPMCTTSTMGDTSVLTS 7811
Query: 1214 VDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKETET 1273
T + A + P L + G E TS + S VP +I +KE T
Sbjct: 7812 TPAFLETRRIQTELASSLTPGLRE-SSGSEGTSSGTKMSTVLSKVPTGATTEI-SKEDVT 7869
Query: 1274 DIDREYFTTSSPPATQ------PTRPPTVEDKE-------------AFGPQALSTPQPPA 1314
I +T SP + T P E E G L T +
Sbjct: 7870 SIPGPAQSTISPDISTRTVSWFSTSPVMTESAEITMNTHTSPLGATTQGTSTLDTSSTTS 7929
Query: 1315 STKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMAEILPE 1374
T H I+ + +MS L G + S P E+T P LM+
Sbjct: 7930 LTMTHSTIS------QGFSHSQMSTLMRRGP--EDVSWMSPPLLEKTRPSFSLMSSPATT 7981
Query: 1375 FPDIIEIDLYHSEENEE------EEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAE 1428
P + L S + A TD+ S N +++ + A
Sbjct: 7982 SPSPVSSTLPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPVTNSPANLSSTSVEILATS 8041
Query: 1429 ARRGQFESVAPSQN------FSDSSESDTHPFVIAKTELSTAVQPNESTETTESLEVTWK 1482
E PS N + SS ++ FV+A ++ S P T T E V+
Sbjct: 8042 EVTTDTEKTHPSSNRTVTDVGTSSSGHESTSFVLADSQTSKVTSPMVITSTMEDTSVSTS 8101
Query: 1483 PETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQAHEHTEPVSL 1542
+ ETS PT ++ +G TE T + P
Sbjct: 8102 TPGFFETS------RIQTEPTSSLTLGLRKTSSSEGTSLATEMSTVLS------GVPTGA 8149
Query: 1543 FPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVT 1602
E S E+ + FA+ T V TS T T T +P+S+ S E +
Sbjct: 8150 TAEVSRTEVTSSSRTSISGFAQLT-------VSPETS-TETITRLPTSSIMTESAEMMIK 8201
Query: 1603 LIGNP---WPDDL----LSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDTMFTM 1655
+P P+ +ST +WVE S S + S D ++
Sbjct: 8202 TQTDPPGSTPESTHTVDISTTPNWVETHSTVTQRFSHSEMTTLVSRS-----PGDMLWPS 8256
Query: 1656 VTDLSQRNTTDTLITLDTSRIITESFFEVPATTI--YPVSEQPSAKVVPTKFVSETD--- 1710
+ + + ++ +L++L T S V +T + +P + P ++ V TD
Sbjct: 8257 QSSVEETSSASSLLSLPA----TTSPSPVSSTLVEDFPSASLPVTSLLNPGLVITTDRMG 8312
Query: 1711 -TSEWISSTTVEEKKRKEEEGTT--GTASTFEVYSSTQRS-DQLILPFELESPNVATSSD 1766
+ E +S+T E TT T T ++ ST + + + SD
Sbjct: 8313 ISREPGTSSTSNLSSTSHERLTTLEDTVDTEDMQPSTHTAVTNVRTSISGHESQSSVLSD 8372
Query: 1767 SGTRKSFMSL-TTPTQSEREMTDSTPVFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLP 1825
S T K+ + TT T E ++ ST F ET+ ++ + ++ S + + E +++
Sbjct: 8373 SETPKATSPMGTTYTMGETSVSISTSDFFETSRIQ-IEPTSSLTSGLRETSSSERISSAT 8431
Query: 1826 RSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEVAGTLSPHVETTFSTEPTGL 1885
++V E SG T +SS ++ Q T+SP + T T
Sbjct: 8432 EG-STVLSEVPSGATTEVSRTEVISSRGTSMSGPDQF------TISPDISTEAIT----- 8479
Query: 1886 VLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPLEEDFSGDFREYSTVS 1945
R+ I S E I+ G P GA G T F ++
Sbjct: 8480 -------RLSTSPIMTESAESAITIETGSP--GATSEGTLTLDTSTTTFWSGTHSTASPG 8530
Query: 1946 HPIAKEETVMMEGSGDAAFRDTQTSPSTVPTSVHISHISDSEGPSSTMVSTSAFPWEEFT 2005
++ T+M GD + ++P+ S +S S S M STS F
Sbjct: 8531 FSHSEMTTLMSRTPGDVPW-------PSLPSVEEASSVSSSLS-SPAMTSTSFF---STL 8579
Query: 2006 SSAEGSGEQLVTVSSSVVPVLPSAVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAE 2065
+ S VT ++ PV + + + S + L + IL T+E
Sbjct: 8580 PESISSSPHPVTALLTLGPVKTTDMLRTSSEPETSSPPNLSSTS--------AEILATSE 8631
Query: 2066 VEGTKAPVEKEEVKVSGTVSTNFPQTIEPAK-LWSRQEVNPVRQEIESETTSEEQIQEEK 2124
V + + V T + + P+ L P + T +
Sbjct: 8632 VTKDREKIHPSSNTPVVNVGTVIYKHLSPSSVLADLVTTKPTSPMATTSTLGNTSVSTST 8691
Query: 2125 SF--ESPQNSPATEQT--IFDSQTFTETELKTTDYSVLTTKKTYSDDKEMKEEDTSLVNM 2180
E+ P + T + + T ET T + L+ T + K + E SL
Sbjct: 8692 PAFPETMMTQPTSSLTSGLREISTSQETSSATERSASLSGMPTGATTKVSRTEALSLGRT 8751
Query: 2181 STPDPDANGLESYTTLPEATEKSHFFLATALVTESIPAEHVVTDS--------------- 2225
STP P + T PE + ++ ++T L T AE +T
Sbjct: 8752 STPGPAQS-----TISPEISTETITRISTPLTTTG-SAEMTITPKTGHSGASSQGTFTLD 8805
Query: 2226 -------PIKKEESTKHFP-KGMRPTIQESDTELLFSGLGSGEEVLPTLPTESVNFTEVE 2277
P +T P GM + ++ + S E+ P P+ V+ + V
Sbjct: 8806 TSSRASWPGTHSAATHRSPHSGMTTPMSRGPEDVSWPSRPSVEKTSP--PSSLVSLSAVT 8863
Query: 2278 QINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEGS--GSVTSTTLIEI 2335
+ LY S ES+ S + R+ ++ V ++ TD+ + S TS + I
Sbjct: 8864 S-PSPLYSTPS--ESSHSSPL----RVTSLFTPV--MMKTTDMLDTSLEPVTTSPPSMNI 8914
Query: 2336 LSD----TGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRP---------------QT 2376
SD T + S + Q T+ +E +S P T
Sbjct: 8915 TSDESLATSKATMETEAIQLSENTAVTQMGTISARQEFYSSYPGLPEPSKVTSPVVTSST 8974
Query: 2377 ITEQDSNKNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPSDLYYEPSGEGSGEV 2436
I + S +++EI ST L + + SA KPS + Y+
Sbjct: 8975 IKDIVSTTIPASSEITRIEMESTSTLTPTPRETSTSQEIHSATKPSTVPYK--------- 9025
Query: 2437 DIVDSFHTSATTQATRQESSTTFVSDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSEQN 2496
A T AT ++S T +S + ++ ++ + +S P+ +E
Sbjct: 9026 ---------ALTSATIEDSMTQVMSSSRGPSPDQSTMSQDISTEVITRLSTS-PIKTEST 9075
Query: 2497 K-----SSPDPTSTLSNTVSYERST---DGSFQDRFREFEDSTLKPNRKKPTENIIIDLD 2548
+ + P +T T++ + ST G+ + F S + + T + L
Sbjct: 9076 EMTITTQTGSPGATSRGTLTLDTSTTFMSGTHSTASQGFSHSQMTALMSR-TPGDVPWLS 9134
Query: 2549 KEDKDLILTITESTILEILPELTSDKNTIIDIDHTK--PVYE----------DILGMQTD 2596
+ + + S ++ + +T+ D H+ PV ++LG ++
Sbjct: 9135 HPSVEEASSASFSLSSPVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLGTSSE 9194
Query: 2597 IDTEVPSEPHDSNDE---SNDDSTQVQEIYEAAVNLSLTEETFEGSADVLAS--YTQATH 2651
+T P ++ E + +T +++ N+ + T E + VLA T+AT
Sbjct: 9195 PETSSPPNLSSTSAEILAITEVTTDTEKL--EMTNVVTSGYTHESPSSVLADSVTTKATS 9252
Query: 2652 DESMTY--------------EDRSQLDHMG-FHFTTGIPAPSTETELDVLLPTATSL-PI 2695
+TY D S++ T G+ S E +T L +
Sbjct: 9253 SMGITYPTGDTNVLTSTPAFSDTSRIQTKSKLSLTPGLMETSISEETSSATEKSTVLSSV 9312
Query: 2696 PRKSATVIPEIEGIKAEAKALDDMFESSTLSDGQAIADQSEIIPTLGQFERTQEEYEDKK 2755
P + T + E I + ++ + ST+S ++ + I L + E T K
Sbjct: 9313 PTGATTEVSRTEAISSSRTSIPGPAQ-STMSSDTSMETITRISTPLTRKESTDMAITPKT 9371
Query: 2756 -HAGPSFQPEFSSGAEEALVDHTPYLSIATTHLMDQSVTEVP------DVMEGSNPPYYT 2808
+G + Q F+ + + P ATT QSV P DV S P
Sbjct: 9372 GPSGATSQGTFT--LDSSSTASWPGTHSATTQRFPQSVVTTPMSRGPEDVSWPS--PLSV 9427
Query: 2809 DTTLAVSTFAKLSSQTPSSPLTIYSGSEASGHTEIPQPSALPGIDVGSSVMSPQDSFKEI 2868
+ S+ SS T SPL YS S H+ S +P + +S+M +
Sbjct: 9428 EKNSPPSSLVSSSSVTSPSPL--YSTPSGSSHS-----SPVPVTSLFTSIMMKATDMLDA 9480
Query: 2869 HVNIEATFKPSSEEYLHITEPPSLS 2893
+ E T P+ ++IT SL+
Sbjct: 9481 SLEPETTSAPN----MNITSDESLA 9501
Score = 94.0 bits (232), Expect = 2e-18
Identities = 496/2380 (20%), Positives = 850/2380 (35%), Gaps = 430/2380 (18%)
Query: 361 ETASP----SLSKEPQMVSDRTTPIIPLVDELPVIPTEFPPVGNIVSFEQKATVQPQAIT 416
ET+SP S S E S+ T D + P+ PV N+ + K +
Sbjct: 8612 ETSSPPNLSSTSAEILATSEVTK------DREKIHPSSNTPVVNVGTVIYKHLSPSSVLA 8665
Query: 417 DSLATKLPTPTGSTKKPWDMDDYSPSASGPLGKLDISEIKEEVLQSTTGVSHYATDSWDG 476
D + TK +P +T + + S S S P + + + T+G+ +T
Sbjct: 8666 DLVTTKPTSPMATTST---LGNTSVSTSTPA--FPETMMTQPTSSLTSGLREISTSQETS 8720
Query: 477 VVEDKQTQES---------VTQIEQIEVG----PLVTSMEILKHIPSKEFPVTETPLVT- 522
++ S V++ E + +G P I I ++ TPL T
Sbjct: 8721 SATERSASLSGMPTGATTKVSRTEALSLGRTSTPGPAQSTISPEISTETITRISTPLTTT 8780
Query: 523 --ARMILESKTEKKMVS--------TVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLI 572
A M + KT S T S G + T + +
Sbjct: 8781 GSAEMTITPKTGHSGASSQGTFTLDTSSRASWPGTHSAATHRSPHSGMTTPMSRGPEDVS 8840
Query: 573 FDQIPEVITVSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRIT 632
+ P +V KTS + L S+SA T+ SPL + S + R+T
Sbjct: 8841 WPSRP---SVEKTSPPS------SLVSLSAVTSPSPLYSTPSESS-------HSSPLRVT 8884
Query: 633 EEFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRERTETLIP 692
F + TT + P S + E ++T +++TE E T +
Sbjct: 8885 SLFTPVMMKTTDMLDTSLEPVTTSPPSMNITSDESLATS-KATMETEAIQLSENTA--VT 8941
Query: 693 EMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKL----STSLSEPIHVTESSVEMTKSFD 748
+M T + E P K V + + ST++ +T +E T +
Sbjct: 8942 QMGTISARQEFYSSYPGLPEPSKVTSPVVTSSTIKDIVSTTIPASSEITRIEMESTST-- 8999
Query: 749 FPTLITKLSAEPTEVRDMEEDFTAT-PGTTKY--------DENITTVLLAHGTLSVEAAT 799
L+ P E +E +AT P T Y ++++T V+ + S + +T
Sbjct: 9000 -------LTPTPRETSTSQEIHSATKPSTVPYKALTSATIEDSMTQVMSSSRGPSPDQST 9052
Query: 800 VSKWSWDEDNTTSKPLESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPD 859
+S+ + +T ST P + + T G G + T D + F
Sbjct: 9053 MSQ----DISTEVITRLSTSPIKTESTEMTITTQTGSPGATSR-GTLTLDTSTTFMSGTH 9107
Query: 860 STQKQ---------LEEVTDEDI----------AAHGKFTIRFQPTTSTGIAEKSTLRDS 900
ST Q L T D+ A+ F++ P ++ STL DS
Sbjct: 9108 STASQGFSHSQMTALMSRTPGDVPWLSHPSVEEASSASFSLS-SPVMTSSSPVSSTLPDS 9166
Query: 901 TTEEKVPPITS--TEGQVYATMEGSALGEVEDVDLSKPVSTVPQFAHTS-EVEGLAFVSY 957
+P +TS T G V T LG + + S P P + TS E+ + V+
Sbjct: 9167 IHSSSLP-VTSLLTSGLVKTT---ELLGTSSEPETSSP----PNLSSTSAEILAITEVTT 9218
Query: 958 SSTQEPTTYVDSS---HTIPLSVIPKT-------DWGVLVPSVPSEDEVLGEPSQDILVI 1007
+ + T V +S H P SV+ + G+ P+ + + + P+
Sbjct: 9219 DTEKLEMTNVVTSGYTHESPSSVLADSVTTKATSSMGITYPTGDT-NVLTSTPAFSDTSR 9277
Query: 1008 DQTRLEATISPETMRTTKITEGTTQEEFPWKEQTAEKPVPALSSTAWTPKEAVTPLDEQE 1067
QT+ + +++P M T+ E ++ E + T VP ++T + EA++
Sbjct: 9278 IQTKSKLSLTPGLMETSISEETSSATE----KSTVLSSVPTGATTEVSRTEAISSSRTSI 9333
Query: 1068 GDGSAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIG 1127
+ T+S D + R+ +TP+ + K TD + +TP+ G
Sbjct: 9334 PGPAQSTMSSDTSMETITRI----STPLTR---------------KESTD--MAITPKTG 9372
Query: 1128 PKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEK 1187
P + S G + + SST + + S + Q + TT ED+ S L +
Sbjct: 9373 PSGATSQGT---FTLDSSSTASWPGTHSATTQRFPQSVV-TTPMSRGPEDVSWPSPLSVE 9428
Query: 1188 PKATELIEFSTIKVTVPSDITTAFSSVDR---LHTTSAFKPSSAITKKPPLIDREPGEET 1244
+ S+ VT PS + + S + TS F +S + K ++D ET
Sbjct: 9429 KNSPPSSLVSSSSVTSPSPLYSTPSGSSHSSPVPVTSLF--TSIMMKATDMLDASLEPET 9486
Query: 1245 TSDM---VIIGESTSHVPPTT-------LEDIVAKETETDIDREYFTTSSPPATQPTRPP 1294
TS + ES + TT E+ A ET E +SSP ++PT+
Sbjct: 9487 TSAPNMNITSDESLAASKATTETEAIHVFENTAASHVETTSATEELYSSSPGFSEPTKVI 9546
Query: 1295 T-VEDKEAFGPQALSTPQPPASTKFHPDI---NVYIIEVRENKTGR----MSDLSVIGHP 1346
+ V + +ST P +S +I + +RE +T + ++ S + +
Sbjct: 9547 SPVVTSSSIRDNMVSTTMPGSSGITRIEIESMSSLTPGLRETRTSQDITSSTETSTVLYK 9606
Query: 1347 IDSE-----SKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECAN--- 1398
+ S S+ + S T + + + D + L S E E
Sbjct: 9607 MPSGATPEVSRTEVMPSSRTSIPGPAQSTMSLDISDEVVTRLSTSPIMTESAEITITTQT 9666
Query: 1399 ----ATDVTTTP---SVQYINGKHLVTTVPKDPEAAEAR----RGQFESVAPSQNFSDSS 1447
AT T P S+ +++G H +T+ + +E RG S F +++
Sbjct: 9667 GYSLATSQVTLPLGTSMTFLSGTH--STMSQGLSHSEMTNLMSRGPESLSWTSPRFVETT 9724
Query: 1448 ESDTHPFVIAKTELSTAVQPNEST---------------------ETTESLEVTWKPETY 1486
S + + L+T++ P ST +TTE L+ + +P+T
Sbjct: 9725 RSSSS---LTSLPLTTSLSPVSSTLLDSSPSSPLPVTSLILPGLVKTTEVLDTSSEPKT- 9780
Query: 1487 PETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQAHEH----TEPVSL 1542
+S + S ++ T + E R + H++H +E
Sbjct: 9781 -SSSPNLSSTSVEIPATSEIMTDTEKIHPSSNTAVAKVRTSSSVHESHSSVLADSETTIT 9839
Query: 1543 FPEESSGEIAIDQE--SQKIAFARA----TEVTFG--------EEVEKSTSVTYTPTI-- 1586
P D + AF+ TE TF E++TS+T T +
Sbjct: 9840 IPSMGITSAVDDTTVFTSNPAFSETRRIPTEPTFSLTPGFRETSTSEETTSITETSAVLY 9899
Query: 1587 -VPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEA 1645
VP+SA+ VS E ++ PD ST +P + E+ IT S +
Sbjct: 9900 GVPTSATTEVSMTEIMSSNRIHIPDSDQSTM------SPDIITEV-------ITRLSSSS 9946
Query: 1646 EEDEDTMFTMVTDLSQRNTT--DTLITLDTSRIITESFFEVPA-------TTIYPVS-EQ 1695
E T T+ T S T TL T+ + + VP TT+ S E
Sbjct: 9947 MMSESTQMTITTQKSSPGATAQSTLTLATTTAPLARTHSTVPPRFLHSEMTTLMSRSPEN 10006
Query: 1696 PSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFE 1755
PS K + FV +T +S + S V + + + SS+ L+ P
Sbjct: 10007 PSWK--SSLFVEKTSSSSSLLSLPVTTSP------SVSSTLPQSIPSSSFSVTSLLTPGM 10058
Query: 1756 LESPNVATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTETNTLE--NLGAQTTEHS--- 1810
+++ + +T + + + + E+T T ++++ N+G ++ H
Sbjct: 10059 VKTTDTSTEPGTSLSPNLSGTSVEILAASEVTTDTEKIHPSSSMAVTNVGTTSSGHELYS 10118
Query: 1811 --SIHQPGVQEGLTTLP-RSPASVFMEQGSGEAAADPETTTV--------------SSFS 1853
SIH + T P +P+S+ S A+ ETT ++ S
Sbjct: 10119 SVSIHS---EPSKATYPVGTPSSMAETSISTSMPANFETTGFEAEPFSHLTSGFRKTNMS 10175
Query: 1854 LNVEYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLG 1913
L+ ++ + S H+ + T+ T ++ D A T+ +I+
Sbjct: 10176 LDTS-SVTPTNTPSSPGSTHLLQSSKTDFTSSAKTSSPDWPPASQYTEIPVDIITPFN-A 10233
Query: 1914 EPNYGAEIRGFSTGFPLEEDFSGDFREYST-VSHPIAKEETVMMEGSGDAAFRDTQTSPS 1972
P+ E G T FP E F+ E + +S + + G+ + + TS +
Sbjct: 10234 SPSI-TESTGI-TSFP-ESRFTMSVTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFA 10290
Query: 1973 T--VPTSVHISHISDSE---GPSSTMVSTSAFPWEEFTSSAEG--SGEQLVTVSSSVVPV 2025
T VP ++ S S GP +ST A E SS S T SS +P
Sbjct: 10291 TTGVPRAISGSGSPFSRTESGPGDATLSTIA---ESLPSSTPVPFSSSTFTTTDSSTIPA 10347
Query: 2026 L---------PSAVQKFSGTASSIIDEGLGEVGTVNEIDR--RSTILPTAEVEGTKAPVE 2074
L P V GT SS + L V T++ + R++ P + T
Sbjct: 10348 LHEITSSSATPYRVDTSLGTESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMT----- 10402
Query: 2075 KEEVKVSGTVSTNFPQTIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPA 2134
E V++ GTV++ + +L + +I +E I+ K ++ SPA
Sbjct: 10403 -ESVEL-GTVTSAYQVPSLSTRLTRTDGIMEHITKIPNEAAHRGTIRPVKGPQT-STSPA 10459
Query: 2135 TEQTIFDSQT-----------FTETELKTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTP 2183
+ + + T T T LKTT + LTT Y+ + + M++
Sbjct: 10460 SPKGLHTGGTKRMETTTTALKTTTTALKTTSRATLTTS-VYTPTLGTLTPLNASMQMAST 10518
Query: 2184 DPDANGLESYTTLPEATEKSHFFLATALVTESIPAEHVVTDSPIKKEEST---------- 2233
P + + P+ E + LAT+L E+ A T S +E T
Sbjct: 10519 IPTEMMITTPYVFPDVPETTSS-LATSLGAETSTALPRTTPSVFNRESETTASLVSRSGA 10577
Query: 2234 KHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLPTESVNF--TEVEQINNTLYPHTSQVE 2291
+ P + S+ + S + E +PT+ + NF +E++ +++T H + V
Sbjct: 10578 ERSPVIQTLDVSSSEPDTTASWVIHPAETIPTVSKTTPNFFHSELDTVSSTATSHGADVS 10637
Query: 2292 STSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVTSTTLIEILSDTGAEGPTVAPLPF 2351
S I L + T + SG+ TSTT PT+ P
Sbjct: 10638 SAIPTNISP-----------SELDALTPLVTISGTDTSTTF-----------PTLTKSPH 10675
Query: 2352 STDIGHPQNQTVRWAEEIQTSRPQTITEQDSNKNSSTAEINETTTSSTDFLARAYGFEMA 2411
T+ + + E ++ P+TI +++ +T I + + T A
Sbjct: 10676 ETET---RTTWLTHPAETSSTIPRTIPNFSHHESDATPSIATSPGAETS---------SA 10723
Query: 2412 KEFVTSAPKPSDLYYEPSGEGSGEVDIVDSFHTSATTQATRQESSTTFVSDGSLEKHPEV 2471
+T +P G D+V S TS+ T +++ +
Sbjct: 10724 IPIMTVSP--------------GAEDLVTSQVTSSGT-----------------DRNMTI 10752
Query: 2472 PSAKAVTADGFPTVSVMLPLHSEQNKSSPDPTSTLSNTVS 2511
P+ + G P L H E SS PTST+S VS
Sbjct: 10753 PTL--TLSPGEPKTIASLVTHPEAQTSSAIPTSTISPAVS 10790
Score = 93.6 bits (231), Expect = 3e-18
Identities = 540/2758 (19%), Positives = 949/2758 (34%), Gaps = 464/2758 (16%)
Query: 509 PSKEFPVTETPLVTARMILESKTEKKMVST--VSELVTTGHYGFTLGEEDDEDRTLTVGS 566
PS PV V + + S +V+T S + TT G T T+ +
Sbjct: 8641 PSSNTPVVNVGTVIYKHLSPSSVLADLVTTKPTSPMATTSTLGNTSVSTSTPAFPETMMT 8700
Query: 567 DESTLIFDQIPEVITVSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQ 626
++ + + E+ T +TS T + A+T VS +S +
Sbjct: 8701 QPTSSLTSGLREISTSQETSSATERSASLSGMPTGATTKVSRTEALSLGRTSTPGPAQST 8760
Query: 627 TSGRITEEFLGKYLSTTPFPSQHRTEIELFPYSGDK-------ILVEGISTVIYPSLQTE 679
S I+ E + + +TP + E+ + P +G ++ S +P +
Sbjct: 8761 ISPEISTETITRI--STPLTTTGSAEMTITPKTGHSGASSQGTFTLDTSSRASWPGTHSA 8818
Query: 680 MTHRRERTETLIPEMRTDTYTDEIQEEIT--KSPFMGKTEEEVFSGMKLSTSLSEPIHVT 737
THR + P R E+++ P + KT + + P++ T
Sbjct: 8819 ATHRSPHSGMTTPMSRGP-------EDVSWPSRPSVEKTSPPSSLVSLSAVTSPSPLYST 8871
Query: 738 ESSVEMTKSFDFPTLITKLSAEPTEVRDME-EDFTATPGTTKY--DENITTVLLAHGTLS 794
S + +L T + + T++ D E T +P + DE++ T + T+
Sbjct: 8872 PSESSHSSPLRVTSLFTPVMMKTTDMLDTSLEPVTTSPPSMNITSDESLAT---SKATME 8928
Query: 795 VEAATVSK-WSWDEDNTTSKPLESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADE 853
EA +S+ + + T S E P + + V + KDI S T + E
Sbjct: 8929 TEAIQLSENTAVTQMGTISARQEFYSSYPGLPEPSKVTSPVVTSSTIKDIVSTTIPASSE 8988
Query: 854 FTLIPDSTQKQL-----EEVTDEDIAAHGK-FTIRFQPTTSTGIAEKSTLRDSTTEEKVP 907
T I + L E T ++I + K T+ ++ TS +T+ DS T+
Sbjct: 8989 ITRIEMESTSTLTPTPRETSTSQEIHSATKPSTVPYKALTS------ATIEDSMTQV--- 9039
Query: 908 PITSTEGQVYATMEGSALGEVEDVDLSKPVSTVPQFAHTSEVE--------GLAFVSYSS 959
++S+ G + + S + + ++ +ST P ++E+ G +
Sbjct: 9040 -MSSSRGP---SPDQSTMSQDISTEVITRLSTSPIKTESTEMTITTQTGSPGATSRGTLT 9095
Query: 960 TQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEATISPE 1019
TT++ +H+ + L+ P + L PS V + + ++S
Sbjct: 9096 LDTSTTFMSGTHSTASQGFSHSQMTALMSRTPGDVPWLSHPS----VEEASSASFSLSSP 9151
Query: 1020 TMRTTKITEGTTQEEFPWKEQTAEKPVPALSSTAW--------TPKEAVTPLDEQEGDGS 1071
M ++ T + ++ PV +L ++ T E T S
Sbjct: 9152 VMTSSSPVSSTLPDSI----HSSSLPVTSLLTSGLVKTTELLGTSSEPETSSPPNLSSTS 9207
Query: 1072 AYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVS 1131
A ++ E+ T +E++ + G S S K + +T ++
Sbjct: 9208 AEILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADSVTTKATSSMGITYPTGDTNVLT 9267
Query: 1132 LSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKAT 1191
+P + S T L T I++ T + T L + G+ + T
Sbjct: 9268 STPAFSDTSRIQTKSKLSLTPGL--METSISEETSSATEKSTVLSSVPTGATT--EVSRT 9323
Query: 1192 ELIEFSTIKVTVPSDIT----TAFSSVDRLHTTSAFKPSS--AITKKPPLIDREPGEETT 1245
E I S + P+ T T+ ++ R+ T K S+ AIT K G +
Sbjct: 9324 EAISSSRTSIPGPAQSTMSSDTSMETITRISTPLTRKESTDMAITPKTG----PSGATSQ 9379
Query: 1246 SDMVIIGESTSHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQ 1305
+ ST+ P T TT P + T P + GP+
Sbjct: 9380 GTFTLDSSSTASWPGT----------------HSATTQRFPQSVVTTPMSR------GPE 9417
Query: 1306 ALSTPQPPASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVH 1365
+S P P + K P ++ V + S L + S S P PV
Sbjct: 9418 DVSWPSPLSVEKNSPPSSL----VSSSSVTSPSPL----YSTPSGSSHSSPV-----PVT 9464
Query: 1366 DLMAEILPEFPDIIEIDLYHSEE-----NEEEEEECANATDVTTTPSVQYING---KHLV 1417
L I+ + D+++ L N +E A + T T ++ H+
Sbjct: 9465 SLFTSIMMKATDMLDASLEPETTSAPNMNITSDESLAASKATTETEAIHVFENTAASHVE 9524
Query: 1418 TTVPKD------PEAAEARRGQFESVAPSQNFSDSSESDTHP----FVIAKTELSTAVQP 1467
TT + P +E + V S + D+ S T P + E +++ P
Sbjct: 9525 TTSATEELYSSSPGFSEPTK-VISPVVTSSSIRDNMVSTTMPGSSGITRIEIESMSSLTP 9583
Query: 1468 NESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKG-AESVTERD 1526
ET S ++T ET + SG P+V T S T+ G A+S D
Sbjct: 9584 G-LRETRTSQDITSSTETSTVLYKMPSGATPEVSRTEVMPS---SRTSIPGPAQSTMSLD 9639
Query: 1527 TEVGHQAHEHTEPVSLFPEESSGEIAID-QESQKIAFARATEVTFGEEVEKSTSVTYTPT 1585
T P+ S EI I Q +A ++ T + TS+T+
Sbjct: 9640 ISDEVVTRLSTSPIMT----ESAEITITTQTGYSLATSQVT-------LPLGTSMTFLSG 9688
Query: 1586 IVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEA 1645
S+ S +S E L+ P+ L T +VE T S +S+P+T
Sbjct: 9689 -THSTMSQGLSHSEMTNLMSRG-PESLSWTSPRFVETTRSS----SSLTSLPLT------ 9736
Query: 1646 EEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKF 1705
T LS ++T LD+S +P T++ + +V+ T
Sbjct: 9737 -----------TSLSPVSST----LLDSS-----PSSPLPVTSLILPGLVKTTEVLDTSS 9776
Query: 1706 VSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQR---SDQLILPFELESPNVA 1762
+T +S +SST+VE +T E+ + T++ S + S +V
Sbjct: 9777 EPKTSSSPNLSSTSVE------------IPATSEIMTDTEKIHPSSNTAVAKVRTSSSVH 9824
Query: 1763 TSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTETNTLENLGAQTTEHSSIHQPGVQEGLT 1822
S S S ++T P+ D T VFT TE + PG +E T
Sbjct: 9825 ESHSSVLADSETTITIPSMGITSAVDDTTVFTSNPAFSETRRIPTEPTFSLTPGFRE--T 9882
Query: 1823 TLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEVAGTLSPHVETTFSTEP 1882
+ S+ TT VS + I T+SP +
Sbjct: 9883 STSEETTSITETSAVLYGVPTSATTEVSMTEIMSSNRIHIPDSDQSTMSPDI-------- 9934
Query: 1883 TGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPLEEDFSGDFREYS 1942
++ V+ R+ + ++ S ++ I+ + P GA + T +
Sbjct: 9935 ----ITEVITRLSSSSMMSESTQMTITTQKSSP--GATAQSTLT--------------LA 9974
Query: 1943 TVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVPTSVHISHISDSEGPSSTMVSTSAFPWE 2002
T + P+A+ STVP S ++ S S + +
Sbjct: 9975 TTTAPLARTH-------------------STVPPRFLHSEMTTLMSRSPENPSWKSSLFV 10015
Query: 2003 EFTSSAEGSGEQLVTVSSSVVPVLPSAVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILP 2062
E TSS+ VT S SV LP ++ S + +S++ G+ V T + T L
Sbjct: 10016 EKTSSSSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGM--VKTTDTSTEPGTSL- 10072
Query: 2063 TAEVEGTKAPV--------EKEEVKVSGTVS-TNFPQTIEPAKLWSRQEVN--------- 2104
+ + GT + + E++ S +++ TN T +L+S ++
Sbjct: 10073 SPNLSGTSVEILAASEVTTDTEKIHPSSSMAVTNVGTTSSGHELYSSVSIHSEPSKATYP 10132
Query: 2105 ---PVRQEIESETTSEEQIQEEKSFESPQNSPATE-----QTIFDSQTFTETE------- 2149
P S +TS E FE+ S T D+ + T T
Sbjct: 10133 VGTPSSMAETSISTSMPANFETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSSPGS 10192
Query: 2150 ---LKTTDYSVLTTKKTYSDDKEMKEEDTSL-VNMSTP---DPDANGLESYTTLPEA--- 2199
L+++ ++ KT S D + T + V++ TP P T+ PE+
Sbjct: 10193 THLLQSSKTDFTSSAKTSSPDWPPASQYTEIPVDIITPFNASPSITESTGITSFPESRFT 10252
Query: 2200 ---TEKSHFFLATALVTESIPAEHVV---TDSPIKKEESTKHFPKGMRPTIQESDTELLF 2253
TE +H L T+ +P+ + T P E T G+ I S +
Sbjct: 10253 MSVTESTHH-----LSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRAISGSGSPFSR 10307
Query: 2254 SGLGSGEEVLPTL----------PTESVNFTEVE------------------QINNTLYP 2285
+ G G+ L T+ P S FT + +++ +L
Sbjct: 10308 TESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYRVDTSLGT 10367
Query: 2286 HTSQVES----------------TSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVTS 2329
+S E TSS I D E+V E+G + S + S +T
Sbjct: 10368 ESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESV--ELGTVTSAYQVPSLSTRLTR 10425
Query: 2330 T----TLIEILSDTGAEGPTVAPL---PFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDS 2382
T I + + A T+ P+ ST P+ + ++T+ T +
Sbjct: 10426 TDGIMEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKGLHTGGTKRMETTTTALKTTTTA 10485
Query: 2383 NKNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPSDL---YYEPSGEGSGEVDIV 2439
K +S A + TT+ T L + + ++ P + Y P D+
Sbjct: 10486 LKTTSRATL--TTSVYTPTLGTLTPLNASMQMASTIPTEMMITTPYVFP--------DVP 10535
Query: 2440 DSFHTSATTQATRQESSTTFVSDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSEQNKSS 2499
++ + AT+ ++ + + E +A V+ G V+ L + + S
Sbjct: 10536 ETTSSLATSLGAETSTALPRTTPSVFNRESET-TASLVSRSGAERSPVIQTL--DVSSSE 10592
Query: 2500 PDPTSTL----SNTVSYERSTDGSFQDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDL- 2554
PD T++ + T+ T +F + ST + + I ++ + D
Sbjct: 10593 PDTTASWVIHPAETIPTVSKTTPNFFHSELDTVSSTATSHGADVSSAIPTNISPSELDAL 10652
Query: 2555 --ILTITESTILEILPELTSDKNTIIDIDHTKPVYEDILGMQTDIDTEVPSEPHDSNDES 2612
++TI+ + P LT + + + + I +P+ H +D +
Sbjct: 10653 TPLVTISGTDTSTTFPTLTKSPH---ETETRTTWLTHPAETSSTIPRTIPNFSHHESDAT 10709
Query: 2613 NDDSTQVQEIYEAAVNLSLTEETFEGSADVLAS-YTQATHDESMTYEDRSQLDHMGFHFT 2671
+T +A+ + G+ D++ S T + D +MT + G T
Sbjct: 10710 PSIATSPGAETSSAIPIMTVS---PGAEDLVTSQVTSSGTDRNMTIPTLTL--SPGEPKT 10764
Query: 2672 TGIPAPSTETELDVLLPTATSLPIPRKSATVIPEIEGIKAEAKALDDMFESS------TL 2725
E + +PT+T P + T + + + A+ + +S T+
Sbjct: 10765 IASLVTHPEAQTSSAIPTSTISPAVSRLVTSM--VTSLAAKTSTTNRALTNSPGEPATTV 10822
Query: 2726 SDGQAIADQSEIIPTLGQFERTQEEYEDKKHAGPSFQPEFSSGAEEALVDHTPYLSIATT 2785
S A S +P T + K PS S GAE + TP +S
Sbjct: 10823 SLVTHPAQTSPTVPW-----TTSIFFHSKSDTTPSMTT--SHGAESSSAVPTPTVS---- 10871
Query: 2786 HLMDQSVTEVPDVMEGSNPPYYTDTTLAVSTFAKLSSQTPSSPLTIYS-----GSEASGH 2840
TEVP V+ P T + +ST + + +P P T S G EAS
Sbjct: 10872 -------TEVPGVV----TPLVTSSRAVISTTIPILTLSPGEPETTPSMATSHGEEAS-- 10918
Query: 2841 TEIPQPSALPGI-DVGSSVMSPQDSFKEIHVNIEATFKPSSEEYLHITEPPSLSPDTKLE 2899
+ IP P+ PG+ V +S+++ + + I TF E PS++ E
Sbjct: 10919 SAIPTPTVSPGVPGVVTSLVTSSRAVTSTTIPI-LTFSLGEPE-----TTPSMATSHGTE 10972
Query: 2900 PSEDDGKPELLEEMEASPTELIAVEGTEILQDFQNKTDGQVSGEAIKMFPTIKTPEAGTV 2959
P +L E+ T L+A T E T EA +
Sbjct: 10973 AG--SAVPTVLPEVPGMVTSLVASSRAVTSTTLPTLTLSPGEPETTPSMATSHGAEASST 11030
Query: 2960 ITTADEIELEGATQWPHSTSASATYGVEAGVVPWLSPQTSERPTLSS------------- 3006
+ T E+ G ++ +++ GV + +P L E T S
Sbjct: 11031 VPTVSP-EVPGVV----TSLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEASSAV 11085
Query: 3007 -SPEINPETQAALIRGQDSTIAASEQQVAARILDSND------QATVNPVEFNTEVAT 3057
+P ++P + S+ A + + L S++ AT + VE ++ V T
Sbjct: 11086 PTPTVSPGVSGVVTPLVTSSRAVTSTTIPILTLSSSEPETTPSMATSHGVEASSAVLT 11143
Score = 91.3 bits (225), Expect = 1e-17
Identities = 543/2830 (19%), Positives = 951/2830 (33%), Gaps = 398/2830 (14%)
Query: 414 AITDSLATKLPTPTGSTKKPWDMDDYSPSASGPLGKLDISEIKEEVLQSTTGVSHYATDS 473
++ S AT P+P ST +S PL ++ + L TT + H +++
Sbjct: 7973 SLMSSPATTSPSPVSSTLP-------ESISSSPL---PVTSLLTSGLAKTTDMLHKSSEP 8022
Query: 474 WDGVVEDKQTQESVTQIEQIEVGPLVTSMEILKHIPSKEFPVTETPLV------TARMIL 527
V + S T +E + + T E K PS VT+ T+ ++
Sbjct: 8023 ----VTNSPANLSSTSVEILATSEVTTDTE--KTHPSSNRTVTDVGTSSSGHESTSFVLA 8076
Query: 528 ESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVITVS--KT 585
+S+T K S +V T ED T T G E++ I + +T+ KT
Sbjct: 8077 DSQTSK----VTSPMVITSTM------EDTSVSTSTPGFFETSRIQTEPTSSLTLGLRKT 8126
Query: 586 SEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGKYLSTTPF 645
S E S +T +S ++ G++ + TS T + + T
Sbjct: 8127 SSS---------EGTSLATEMSTVLSGVPTGATAEVSRTEVTSSSRTS--ISGFAQLTVS 8175
Query: 646 PSQHRTEIELFPYSGDKILVEGISTVIY-----PSLQTEMTHRRERTETLIPEMRTDTYT 700
P I P S I+ E +I P E TH + + T T T
Sbjct: 8176 PETSTETITRLPTSS--IMTESAEMMIKTQTDPPGSTPESTHTVDISTTPNWVETHSTVT 8233
Query: 701 D-----EIQEEITKSP--FMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMTKSFDFPTL- 752
E+ +++SP + ++ V S+ LS P + S V T DFP+
Sbjct: 8234 QRFSHSEMTTLVSRSPGDMLWPSQSSVEETSSASSLLSLPATTSPSPVSSTLVEDFPSAS 8293
Query: 753 --ITKLSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNT 810
+T L + + PGT+ +T +H L+ TV
Sbjct: 8294 LPVTSLLNPGLVITTDRMGISREPGTSSTSNLSST---SHERLTTLEDTVDTEDMQPSTH 8350
Query: 811 TSKPLESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTD 870
T+ T S L D + P T +T+ S + +
Sbjct: 8351 TAVTNVRTSISGHESQSSVL--------SDSETPKATSPMGTTYTMGETSVSISTSDFFE 8402
Query: 871 EDIAAHGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQ-VYATMEGSALGEVE 929
I+ +PT+S S LR++++ E++ ++TEG V + + A EV
Sbjct: 8403 TS-------RIQIEPTSSL----TSGLRETSSSERIS--SATEGSTVLSEVPSGATTEVS 8449
Query: 930 DVDL----SKPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWGV 985
++ +S QF + ++ A S++ T +S+ TI T G
Sbjct: 8450 RTEVISSRGTSMSGPDQFTISPDISTEAITRLSTSPIMTESAESAITIETGSPGATSEGT 8509
Query: 986 LVPSVPSEDEVLGEPSQDILVIDQTRLEATISPETMRTTKIT-EGTTQEEFPWKE----Q 1040
L + G S T SP + T T + PW +
Sbjct: 8510 LTLDTSTTTFWSGTHS-------------TASPGFSHSEMTTLMSRTPGDVPWPSLPSVE 8556
Query: 1041 TAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKIDH 1100
A +LSS A T + L E S + V+ L + +L T+ +
Sbjct: 8557 EASSVSSSLSSPAMTSTSFFSTLPESISS-SPHPVTALLTLGPVKTTDMLRTSS----EP 8611
Query: 1101 SVSYPPG--AVTEHKVKTDEVVTLTPRIGPKVS-------------LSPGP--EQKYETE 1143
S PP + + + T EV +I P + LSP T+
Sbjct: 8612 ETSSPPNLSSTSAEILATSEVTKDREKIHPSSNTPVVNVGTVIYKHLSPSSVLADLVTTK 8671
Query: 1144 GSSTTGFTSSL--SPFSTHITQLMEETTTEKTSLEDIDLGSGLFE---KPKATELIEFST 1198
+S TS+L + ST E T+ TS L SGL E + + E S
Sbjct: 8672 PTSPMATTSTLGNTSVSTSTPAFPETMMTQPTS----SLTSGLREISTSQETSSATERSA 8727
Query: 1199 IKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHV 1258
+P+ TT S + L P A + P I E ++ + G + +
Sbjct: 8728 SLSGMPTGATTKVSRTEALSLGRTSTPGPAQSTISPEISTETITRISTPLTTTGSAEMTI 8787
Query: 1259 PPTTLEDIVAKETETDID---REYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPAS 1315
P T + + +D R + + AT + + + GP+ +S P P+
Sbjct: 8788 TPKTGHSGASSQGTFTLDTSSRASWPGTHSAATHRSPHSGMTTPMSRGPEDVSWPSRPSV 8847
Query: 1316 TKFHPDINVYIIEVRENKTGRMSDLSVIGH--PIDSESKEDEPCSEETDPVHDLMAEILP 1373
K P ++ + + + S S H P+ S + TD + + +
Sbjct: 8848 EKTSPPSSLVSLSAVTSPSPLYSTPSESSHSSPLRVTSLFTPVMMKTTDMLDTSLEPVTT 8907
Query: 1374 EFPDI-IEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKH-LVTTVPKDPEAAEARR 1431
P + I D + E E ++ T + I+ + ++ P PE ++
Sbjct: 8908 SPPSMNITSDESLATSKATMETEAIQLSENTAVTQMGTISARQEFYSSYPGLPEPSKVTS 8967
Query: 1432 GQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSE 1491
S S + + + I ST T T++ + KP T P +
Sbjct: 8968 PVVTSSTIKDIVSTTIPASSEITRIEMESTSTLTPTPRETSTSQEIHSATKPSTVPYKAL 9027
Query: 1492 HFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFPEE----- 1546
+ E + + S +S +D T P+ E
Sbjct: 9028 TSATIEDSMTQVM------SSSRGPSPDQSTMSQDISTEVITRLSTSPIKTESTEMTITT 9081
Query: 1547 --------SSGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSASAYVSEE 1598
S G + +D + ++ +T + + ++ TP VP + V E
Sbjct: 9082 QTGSPGATSRGTLTLDTSTTFMSGTHSTASQGFSHSQMTALMSRTPGDVPWLSHPSVEEA 9141
Query: 1599 EAVTL-IGNPW---PDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDTMFT 1654
+ + + +P + ST + ++ V L S + TE G + E E +
Sbjct: 9142 SSASFSLSSPVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLGTSSEPETSSPP 9201
Query: 1655 MVTDLSQRNTTDTLITLDTSR-----IITESF-FEVPATTI---------------YPVS 1693
++ S T +T DT + ++T + E P++ + YP
Sbjct: 9202 NLSSTSAEILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADSVTTKATSSMGITYPTG 9261
Query: 1694 E----------------QPSAKVVPTKFVSETDTSEWISSTTVEEKKRKE-EEGTTGTAS 1736
+ Q +K+ T + ET SE SS T + G T S
Sbjct: 9262 DTNVLTSTPAFSDTSRIQTKSKLSLTPGLMETSISEETSSATEKSTVLSSVPTGATTEVS 9321
Query: 1737 TFEVYSSTQRSDQLILPFELESPNVATSSDSGTRKSFMSLTTPTQSEREMTD-------- 1788
E SS++ S + P +T S + ++ ++TP + +E TD
Sbjct: 9322 RTEAISSSRTS--------IPGPAQSTMSSDTSMETITRISTPL-TRKESTDMAITPKTG 9372
Query: 1789 ---STPVFTETNTLENLGAQTTEHSSIHQPGVQEGLTT-LPRSPASVFMEQGSGEAAADP 1844
+T T T + + HS+ Q Q +TT + R P V P
Sbjct: 9373 PSGATSQGTFTLDSSSTASWPGTHSATTQRFPQSVVTTPMSRGPEDVSWPSPLSVEKNSP 9432
Query: 1845 ETTTVSSFSLNVEYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSR 1904
++ VSS S+ + + + SP T+ T + + E + +
Sbjct: 9433 PSSLVSSSSVTSPSPLYSTPSGSSHSSPVPVTSLFTSIMMKATDMLDASLEPETTSAPNM 9492
Query: 1905 EIVISERLGEPNYGAE---IRGFSTGFPLEEDFSGDFREYSTVSHPIAKEETVMMEGSGD 1961
I E L E I F + + E + S ++ V+
Sbjct: 9493 NITSDESLAASKATTETEAIHVFENTAASHVETTSATEELYSSSPGFSEPTKVISPVVTS 9552
Query: 1962 AAFRDTQTSPSTVPTSVHISHISDSEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSS 2021
++ RD S +T+P S I+ I S T ++ TSS E S L + S
Sbjct: 9553 SSIRDNMVS-TTMPGSSGITRIEIESMSSLTPGLRETRTSQDITSSTETS-TVLYKMPSG 9610
Query: 2022 VVP------VLPSAVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEK 2075
P V+PS+ G A S + + + + R ST +P+
Sbjct: 9611 ATPEVSRTEVMPSSRTSIPGPAQSTMSLDISD----EVVTRLST-----------SPIMT 9655
Query: 2076 EEVKVSGTVSTNFPQTIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQN---- 2131
E +++ T T + L + Q P+ + + + + + S N
Sbjct: 9656 ESAEITITTQTGY-------SLATSQVTLPLGTSMTFLSGTHSTMSQGLSHSEMTNLMSR 9708
Query: 2132 --------SPATEQTIFDSQTFTETELKTTDYSVLTTKKTYSDDKEMKEEDTSLVNM--S 2181
SP +T S + T L T+ V +T S + L + +
Sbjct: 9709 GPESLSWTSPRFVETTRSSSSLTSLPLTTSLSPVSSTLLDSSPSSPLPVTSLILPGLVKT 9768
Query: 2182 TPDPDANGLESYTTLPEATEKSHFFLATALVTESIPAEHVVTDSPIKKEESTKHFPKGMR 2241
T D + ++ P + S AT+ + H +++ + K ++ +
Sbjct: 9769 TEVLDTSSEPKTSSSPNLSSTSVEIPATSEIMTDTEKIHPSSNTAVAKVRTSSSVHESHS 9828
Query: 2242 PTIQESDTELLFSGLGSGEEVLPTLPTESVNFTEVEQINNTLYPHTSQVESTSSDKIEDF 2301
+ +S+T + +G T +V+ T V +N + T ++ + + +
Sbjct: 9829 SVLADSETTITIPSMGI---------TSAVDDTTVFT-SNPAFSETRRIPTEPTFSLTPG 9878
Query: 2302 NRMENVAKEVGPLVSQTDIFEG--SGSVTSTTLIEILSDTGAEGPTVAPLPFSTDIGHPQ 2359
R + ++E + + + G + + T ++ EI+S P S DI
Sbjct: 9879 FRETSTSEETTSITETSAVLYGVPTSATTEVSMTEIMSSNRIHIPDSDQSTMSPDIITEV 9938
Query: 2360 NQTVRWAEEIQTSRPQTITEQDSNKNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAP 2419
+ + + S TIT Q S+ + TA+ T ++T LAR + T P
Sbjct: 9939 ITRLSSSSMMSESTQMTITTQKSSPGA-TAQSTLTLATTTAPLARTHS--------TVPP 9989
Query: 2420 KPSDLYYEPSGEGSGEVDIVDSFHTSATTQATRQESSTTFVSDGSLEKHPEVPSAKAVTA 2479
+ H+ TT +R + ++ S +EK S ++
Sbjct: 9990 R--------------------FLHSEMTTLMSRSPENPSWKSSLFVEKTSSSSSLLSLPV 10029
Query: 2480 DGFPTVSVMLPLHSEQNKSSPDPTSTLSNTVSYERSTDGSFQDRFREFEDSTLKPNRKKP 2539
P+VS LP Q+ S + T T ++TD S + ++L PN
Sbjct: 10030 TTSPSVSSTLP----QSIPSSSFSVTSLLTPGMVKTTDTSTEP------GTSLSPNLSGT 10079
Query: 2540 TENIII------DLDKEDKDLILTITESTILEILPELTSDKNTIIDIDH-TKPVYEDILG 2592
+ I+ D +K + +T EL S + + T PV
Sbjct: 10080 SVEILAASEVTTDTEKIHPSSSMAVTNVGTTSSGHELYSSVSIHSEPSKATYPVGTPSSM 10139
Query: 2593 MQTDIDTEVPSEPHDSNDESNDDSTQVQEIYEAAVNLSLTEET------FEGSADVLAS- 2645
+T I T +P+ + E+ S + ++L + T GS +L S
Sbjct: 10140 AETSISTSMPANFETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSSPGSTHLLQSS 10199
Query: 2646 ---YTQATHDESMTYEDRSQLDHMGFHFTTGIPAPSTETELDVLLPTATSLPIPRKSATV 2702
+T + S + SQ + T A + TE + TS P R + +V
Sbjct: 10200 KTDFTSSAKTSSPDWPPASQYTEIPVDIITPFNASPSITESTGI----TSFPESRFTMSV 10255
Query: 2703 IPEIEGIKAEAKALDDMFESSTLSDGQAIADQSEIIPTLGQFERTQEEYEDKKHAGPSFQ 2762
+ D + + T+S G + SE + + F T P +
Sbjct: 10256 TESTHHLST-----DLLPSAETISTGTVMPSLSEAMTS---FATTGVPRAISGSGSPFSR 10307
Query: 2763 PEFSSG------AEEALVDHTP--YLSIATTHLMDQSVTEVPDVMEGSNPPYYTDTTLAV 2814
E G E+L TP + S T ++ + ++ S PY DT+L
Sbjct: 10308 TESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYRVDTSLGT 10367
Query: 2815 STFAKLSSQTPSSPLTIYSGSEASGHTEIPQPSALPGIDVG---SSVMSPQDSFKEIHVN 2871
+ S L S + + I +++G S+ P S + +
Sbjct: 10368 ESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSLSTRLTRTD 10427
Query: 2872 --IEATFKPSSEEYLHITEPPSLSPDTKLEPSEDDGKPELLEEMEASPTELIAVEGTEIL 2929
+E K +E T P P T P+ G + GT+ +
Sbjct: 10428 GIMEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKG---------------LHTGGTKRM 10472
Query: 2930 QDFQNKTDGQVSGEAIKMFPT-IKTPEAGTVITTADEIELEGATQWPHSTSASATYGVEA 2988
+ + A+K T +KT T+ T+ L T S ++T E
Sbjct: 10473 ---------ETTTTALKTTTTALKTTSRATLTTSVYTPTLGTLTPLNASMQMASTIPTEM 10523
Query: 2989 GV-VPWLSPQTSERPTLSSSPEINPETQAALIRGQDSTIAASEQQVAARILDSNDQATVN 3047
+ P++ P E T S + + ET AL R S + A+ L S A +
Sbjct: 10524 MITTPYVFPDVPE-TTSSLATSLGAETSTALPRTTPSVFNRESETTAS--LVSRSGAERS 10580
Query: 3048 PVEFNTEVAT 3057
PV +V++
Sbjct: 10581 PVIQTLDVSS 10590
Score = 87.0 bits (214), Expect = 3e-16
Identities = 577/2899 (19%), Positives = 971/2899 (33%), Gaps = 525/2899 (18%)
Query: 350 EATTIDLSILAETASPSLSKEPQMVSDRTTPIIPLVDELPVIPTEFPPV-GNIVSFEQKA 408
E+T+ ++ + SPSLS + R P +V L T GN
Sbjct: 88 ESTSRGMTHSEQRTSPSLSPQVNGTPSRNYPATSMVSGLSSPRTRTSSTEGNFTKEASTY 147
Query: 409 TVQPQAITDSLATKLPTPT-------GSTKKPWDMDDYSPSASGPLGKL-DISEIKEEVL 460
T+ + + + K PT ST+ PWD + P+ D + KE
Sbjct: 148 TLTVETTSGPVTEKYTVPTETSTTEGDSTETPWDTRYIPVKITSPMKTFADSTASKENAP 207
Query: 461 QSTTGVSHYATDSWDGVVEDKQTQESVTQIEQ--IEVGPL-------VTSMEILKHIPSK 511
S T TDS +T S + +++ P TS+E++
Sbjct: 208 VSMTPAETTVTDSHT----PGRTNPSFGTLYSSFLDLSPKGTPNSRGETSLELILSTTGY 263
Query: 512 EFPV------------TETPLVTARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDED 559
F T PL ++ +L++K + + + L +
Sbjct: 264 PFSSPEPGSAGHSRISTSAPLSSSASVLDNKISETSIFSGQSLTSP-------------- 309
Query: 560 RTLTVGSDE---STLIFDQIPEVITVS--KTSEDTIHTHLEDLESVSASTTVSPLIMPDN 614
L+ G E ST+ IP +T+S +TS + + + + L + S ST
Sbjct: 310 --LSPGVPEARASTMPNSAIPFSMTLSNAETSAERVRSTISSLGTPSIST---------- 357
Query: 615 NGSSMDDWEERQTSGRITEEFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYP 674
+QT+ I + T PS H + + G + G ST
Sbjct: 358 ----------KQTAETILT--FHAFAETMDIPSTHIAKTLASEWLGSPGTLGGTSTSALT 405
Query: 675 SLQTEMTHRRERTETLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPI 734
+ T E T T GK E + S P
Sbjct: 406 TTSPSTTLVSEETNT-------------------HHSTSGKETEGTLNTSMTPLETSAPG 446
Query: 735 HVTESSVEMTKSFDFPTLITKLSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLS 794
+E + + + F TL +K+ + T G+T ++ +T AHG+
Sbjct: 447 EESEMTATLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTA--AHGSSD 504
Query: 795 VEAATVSKWS----WDEDNTTSKPLE-------STEPSASSKLPPALLTTVGMNGKDKDI 843
+ AT S S W ++T + E T PS ++ PPA + I
Sbjct: 505 ILRATTSSTSKASSWTSESTAQQFSEPQHTQWVETSPSMKTERPPASTSVAA------PI 558
Query: 844 PSFTEDGADEFTLIPDSTQKQ--LEEVTDEDIAAH---GKFTIRFQPTTSTGIAEKSTLR 898
+ FT + S+ K LEE + + + G T +F T + S+ R
Sbjct: 559 TTSVPSVVSGFTTLKTSSTKGIWLEETSADTLIGESTAGPTTHQFAVPTGISMTGGSSTR 618
Query: 899 DS--TTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVS 956
S TT S+E T+ + + PVS P + T+
Sbjct: 619 GSQGTTHLLTRATASSETSADLTLATNGV----------PVSVSPAVSKTA--------- 659
Query: 957 YSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDEVLG-----------EPSQDI- 1004
+ P S+T+ SVIP+T L S E LG P D
Sbjct: 660 --AGSSPPGGTKPSYTMVSSVIPETS--SLQSSAFREGTSLGLTPLNTRHPFSSPEPDSA 715
Query: 1005 ----------LVIDQTRLEATISPETM-----RTTKITEGTTQEEFPWKEQTAEKPVPAL 1049
L+ + LE +S + T+ IT GT + K +A L
Sbjct: 716 GHTKISTSIPLLSSASVLEDKVSATSTFSHHKATSSITTGTPEISTKTKPSSAVLSSMTL 775
Query: 1050 SSTAWTP---KEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPP 1106
S+ A +P + A +PL G S L T +E P G + S P
Sbjct: 776 SNAATSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESP 835
Query: 1107 GAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLME 1166
++ V V T P L E+ ET S + +S+S T +
Sbjct: 836 STLSLPSVSG--VKTTFSSSTPSTHLFTSGEETEETSNPSVSQPETSVSRVRTTLASTSV 893
Query: 1167 ETTTEKTSLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPS 1226
T T ++ S F + +T +V + +A + L T+
Sbjct: 894 PTPVFPT-MDTWPTRSAQFSSSHLVSELR-ATSSTSVTNSTGSALPKISHLTGTATMSQ- 950
Query: 1227 SAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKETETDIDREYFT---TS 1283
T + D + TT T TT A + FT TS
Sbjct: 951 ---TNRDTFNDSAAPQSTTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATS 1007
Query: 1284 SPPATQPTRPPT--VEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRENKTGRMSDLS 1341
S AT P T + + GP +++ AST P YI E GR+
Sbjct: 1008 SMEATSIREPSTTILTTETTNGPGSMAV----ASTNI-PIGKGYITE------GRLDTSH 1056
Query: 1342 V-IGHPIDSESKEDEPCSEETDPVH-------DLMAEILP----EFPDIIEIDLYHSEEN 1389
+ IG SE+ D ++E+ + D P +F D D+YH
Sbjct: 1057 LPIGTTASSETSMDFTMAKESVSMSVSPSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSR 1116
Query: 1390 EEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQF-------ESVAPSQN 1442
E + T TP + T P P+ AR S P
Sbjct: 1117 EITIPR--DGTSSALTPQ--------MTATHPPSPDPGSARSTWLGILSSSPSSPTPKVT 1166
Query: 1443 FSD--SSESDTHPFVIAKTELSTAVQPN--ESTETTESL--------EVTWKPETYPETS 1490
S S++ T ++ E S PN +T T S + T P P +
Sbjct: 1167 MSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTSLTPSNIPTSGAIGKSTLVPLDTPSPA 1226
Query: 1491 EHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFPEE-SSG 1549
E + + E + + GA + +E + + +P S P S
Sbjct: 1227 TSLEASEGGLPTLSTYPESTNTPSIHLGAHASSESPSTIKLTMASVVKPGSYTPLTFPSI 1286
Query: 1550 EIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPWP 1609
E I + ++A++ + E +T T+ PT T I P
Sbjct: 1287 ETHIHVSTARMAYSSGSSPEMTAPGETNTGSTWDPT----------------TYITTTDP 1330
Query: 1610 DDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTDTLI 1669
D S + S TP V L + + P TE + A + +L+ T I
Sbjct: 1331 KDTSSAQVS----TPHSVRTLRTTENHPKTESATPAAYSGSPKISSSPNLTSPATKAWTI 1386
Query: 1670 TLDTSRIITESFFEVPATTIYPVSEQ----PSAKVVPTKFVSETDTSEWISSTTVEEKKR 1725
T DT+ T+ + A Q P + V+PT + T E S E
Sbjct: 1387 T-DTTEHSTQLHYTKLAEKSSGFETQSAPGPVSVVIPTSPTIGSSTLELTSDVPGEPLVL 1445
Query: 1726 KEEEGTTGTASTFEVYSSTQRSDQLILPFELESPNVATSSDSGTRKSFMSLTTPTQ--SE 1783
E TT T S++ + ++ SP SS T F ++TP+ S+
Sbjct: 1446 APSEQTTITLPMATWLSTSLTEEMASTDLDISSP----SSPMSTFAIFPPMSTPSHELSK 1501
Query: 1784 REMTDSTPVFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAAD 1843
E S T++ TL+ +H I G LTT+P +P
Sbjct: 1502 SEADTSAIRNTDSTTLD-------QHLGIRSLGRTGDLTTVPITPL-------------- 1540
Query: 1844 PETTTVSSFSLNVEYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTV---MDRVVAENIT 1900
TTT +S +E++ QA+ ++ T+SP T + T + S + V E T
Sbjct: 1541 --TTTWTSV---IEHSTQAQDTLSATMSPTHVTQSLKDQTSIPASASPSHLTEVYPELGT 1595
Query: 1901 Q--TSREIVISERLGEPNYGAEIRGFSTGF----PLEEDFSGDFREYSTV---------S 1945
Q +S E + EI T P++ +G T+ S
Sbjct: 1596 QGRSSSEATTFWKPSTDTLSREIETGPTNIQSTPPMDNTTTGSSSSGVTLGIAHLPIGTS 1655
Query: 1946 HPIAKEETVMMEGSGDAAFRDTQTSPSTVPTSVHISHISDSEGPSSTMVSTSAFPWEEFT 2005
P + +E A + + TS IS S G S+++S S E T
Sbjct: 1656 SPAETSTNMALERRSSTATVSMAGTMGLLVTSAPGRSISQSLGRVSSVLSESTT--EGVT 1713
Query: 2006 SSAEGSGEQLVT-----VSSSVVPVLPSAVQKFSGT--ASSIIDEGLGEVGTVNEIDRRS 2058
S++GS +L T +SSS+ P Q + SS + +G +
Sbjct: 1714 DSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMSTSIPLTSSPTTPDVEFIGGSTFWTKEV 1773
Query: 2059 TILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQTIEPAKLWSRQEVNPVRQEIESETTSEE 2118
T + T+++ + A E + T + +E T +E
Sbjct: 1774 TTVMTSDISKSSARTESSSATLMSTALGS------------------------TENTGKE 1809
Query: 2119 QIQEEKSFESPQNSPATEQTIFDSQTFTETELKTTD-----YSVLTTKK-TYSDDKEMKE 2172
+++ S + P +P+ E T + S T + TTD + V T+ T + D+ +
Sbjct: 1810 KLRTA-SMDLPSPTPSMEVTPWISLTLSNAP-NTTDSLDLSHGVHTSSAGTLATDRSL-- 1865
Query: 2173 EDTSLVNMSTPDPDANGLESYTTLPEATEKSHFFLATALVTESIPAEHVVTDSPIKKEES 2232
+T + S + ++ ++ +T S + + V+ SI H ++ E+
Sbjct: 1866 -NTGVTRASRLENGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSI---HPRPETSAPGAET 1921
Query: 2233 TKHFPKGMR------PTIQESDTELLFSGLGSGEEVLPTLPTES--VNFTEVEQINNTLY 2284
T G R P E++ +G+ SG ++ T S T V T+
Sbjct: 1922 TLTSTPGNRAISLTLPFSSIPVEEVISTGITSGPDINSAPMTHSPITPPTIVWTSTGTIE 1981
Query: 2285 PHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVTSTTLIEILSDTGAEGP 2344
T + + SS+K+ +V + P V+ + S S T + S T +
Sbjct: 1982 QSTQPLHAVSSEKV-------SVQTQSTPYVNSVAV---SASPTHENSVSSGSSTSSPYS 2031
Query: 2345 TVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDS-------------NKNSSTAEI 2391
+ + + I +N W ++ TS P T S N +S+T E
Sbjct: 2032 SASLESLDSTISR-RNAITSWLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEF 2090
Query: 2392 NETTTSSTDFLAR------AYGFE--MAKEFVTSAPKPSDLYYEPSGEG-SGEVDIVDSF 2442
+ +ST + +G + A T A + L P G S EV + +
Sbjct: 2091 PLFSAASTSAAKQRNPETETHGPQNTAASTLNTDASSVTGLSETPVGASISSEVPLPMAI 2150
Query: 2443 HTSA-----TTQATRQESSTTFVSDGS-LEKHPEVPSAKAVTADGFP----TVSVMLPLH 2492
+ + T+++T S T S G+ L + +P+++++ + TVS+ L H
Sbjct: 2151 TSRSDVSGLTSESTANPSLGTASSAGTKLTRTISLPTSESLVSFRMNKDPWTVSIPLGSH 2210
Query: 2493 SEQN--------KSSPDPTSTLSN--------------TVSYERSTD------GSFQDR- 2523
N + P ST+++ TVS+ S D F ++
Sbjct: 2211 PTTNTETSIPVNSAGPPGLSTVASDVIDTPSDGAESIPTVSFSPSPDTEVTTISHFPEKT 2270
Query: 2524 ---FREFEDST--------------------LKPNRKKPTENI-----IIDLDKEDKDLI 2555
FR T KP P+ + I ++
Sbjct: 2271 THSFRTISSLTHELTSRVTPIPGDWMSSAMSTKPTGASPSITLGERRTITSAAPTTSPIV 2330
Query: 2556 LT--ITESTILEILPELTSDKNTIIDIDHTKPVYEDILGMQTDIDTEVPSEPHDSNDESN 2613
LT TE++ + + E T + I+D T + D I+T + S D ++
Sbjct: 2331 LTASFTETSTVSLDNETTVKTSDILDARKTNELPSDSSSSSDLINTSIASSTMDVTKTAS 2390
Query: 2614 DDSTQVQEIYEAAVNLSLTEETFEGSADVLASYTQATHDESMTYEDRSQLDHMGFHFTTG 2673
T + + + S + F + + T T+ + + G G
Sbjct: 2391 ISPTSI-----SGMTASSSPSLFSSDRPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGG 2445
Query: 2674 IPAPSTETELDVLLPTATSLPI-----PRKSATVIPEIEGIKAEAKALDDMFESSTLSDG 2728
PST + P TS + P ++ + + + E + +S + G
Sbjct: 2446 --TPSTLPPFTITHPVETSSALLAWSRPVRTFSTMVSTDTASGENPTSSNSVVTSVPAPG 2503
Query: 2729 Q-AIADQSEIIPTLGQFERTQEEYEDKKHAGPSFQPEFSSGAEEALVDHTPYLSIATTHL 2787
+ +P +G F +T E + +P + TP+LS A
Sbjct: 2504 TWTSVGSTTDLPAMG-FLKTSPAGEAHSLLASTIEPATA---------FTPHLSAA---- 2549
Query: 2788 MDQSVTEVPDVMEGSNPPYYTDTTLAVSTFAKLSSQTPSSPLTIYSGSEASGHTEIPQPS 2847
V+ GS+ ++ +L ++ +K +P +P T SG A+ T S
Sbjct: 2550 ----------VVTGSSAT--SEASLLTTSESKAIHSSPQTPTTPTSG--ANWETSATPES 2595
Query: 2848 ALPGIDVGSSVMSPQDSFKEIHVNIEATFKPS---SEEYLHITEPPSLSPDTKLEP-SED 2903
L + + ++ + + + + PS S L P+L PDT P +
Sbjct: 2596 LLVVTETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFPTLLPDTPAIPLTAT 2655
Query: 2904 DGKPELLEEMEASPTELIAVEGTEILQDFQNKTDGQVSGEAIKMFPTIKTPEAGTVITTA 2963
+ L +++P IA + + + +G+A+ + T+ P+ +
Sbjct: 2656 EPTSSLATSFDSTPLVTIASDSLGTVPETTLTMSETSNGDAL-VLKTVSNPD-----RSI 2709
Query: 2964 DEIELEGATQWP-HSTSAS 2981
I ++G T+ P H +S S
Sbjct: 2710 PGITIQGVTESPLHPSSTS 2728
Score = 83.2 bits (204), Expect = 4e-15
Identities = 498/2344 (21%), Positives = 804/2344 (34%), Gaps = 414/2344 (17%)
Query: 416 TDSLATKLPTPTGSTKKPWDMDDYSPSASGPLGKLDISEIKEEVLQSTTGVSHYATD-SW 474
TD T P+G+T + D S +AS P G + + TT +S D SW
Sbjct: 9363 TDMAITPKTGPSGATSQGTFTLDSSSTASWP-GTHSATTQRFPQSVVTTPMSRGPEDVSW 9421
Query: 475 DGVVEDKQTQESVTQIEQIEVGPLVTSMEILKHIPS---KEFPVTETPLVTARMILESKT 531
+ ++ + + V TS L PS PV T L T+ M
Sbjct: 9422 PSPLSVEKNSPPSSLVSSSSV----TSPSPLYSTPSGSSHSSPVPVTSLFTSIM------ 9471
Query: 532 EKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVITVSKTSEDTIH 591
+ T +L E + + SDES E + E+T
Sbjct: 9472 ----------MKATDMLDASLEPETTSAPNMNITSDESLAASKATTETEAIH-VFENTAA 9520
Query: 592 THLEDLESVSASTTVSP-------LIMPDNNGSSMDDWEERQT---SGRITEEFLGKYLS 641
+H+E + + SP +I P SS+ D T S IT + S
Sbjct: 9521 SHVETTSATEELYSSSPGFSEPTKVISPVVTSSSIRDNMVSTTMPGSSGITRIEIESMSS 9580
Query: 642 TTPFPSQHRTEIELFPYSGDKILVEGISTVIY--PSLQTEMTHRRE---RTETLIPEMRT 696
TP + RT S D STV+Y PS T R E + T IP
Sbjct: 9581 LTPGLRETRT-------SQDITSSTETSTVLYKMPSGATPEVSRTEVMPSSRTSIPGPAQ 9633
Query: 697 DTYT----DEIQEEITKSPFMGKTEEEVFS---GMKLSTS-LSEPIHVTESSVE-----M 743
T + DE+ ++ SP M ++ E + G L+TS ++ P+ + + + M
Sbjct: 9634 STMSLDISDEVVTRLSTSPIMTESAEITITTQTGYSLATSQVTLPLGTSMTFLSGTHSTM 9693
Query: 744 TKSFDFPTLITKLSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEAATVSKW 803
++ + +S P + F T T+ ++T++ L V + +
Sbjct: 9694 SQGLSHSEMTNLMSRGPESLSWTSPRFVET---TRSSSSLTSLPLTTSLSPVSSTLL--- 9747
Query: 804 SWDEDNTTSKPLESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQK 863
D++ S PL P S LP + TT ++ + S + + + IP ++
Sbjct: 9748 ----DSSPSSPL----PVTSLILPGLVKTTEVLDTSSEPKTSSSPNLSSTSVEIPATS-- 9797
Query: 864 QLEEVTDEDIAAHGKFTIRFQPTTSTGIAEK--STLRDSTTEEKVPP--ITSTEGQVYAT 919
E +TD + T + TS+ + E S L DS T +P ITS
Sbjct: 9798 --EIMTDTEKIHPSSNTAVAKVRTSSSVHESHSSVLADSETTITIPSMGITSAVDDTTVF 9855
Query: 920 MEGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSS-----------TQEPTTYVD 968
A E + S P F TS E ++ +S T+ T +
Sbjct: 9856 TSNPAFSETRRIPTEPTFSLTPGFRETSTSEETTSITETSAVLYGVPTSATTEVSMTEIM 9915
Query: 969 SSHTIPLSVIPKTDWGVLVPSVPSE-------DEVLGEPSQDILVIDQT----------- 1010
SS+ I IP +D + P + +E ++ E +Q + ++
Sbjct: 9916 SSNRIH---IPDSDQSTMSPDIITEVITRLSSSSMMSESTQMTITTQKSSPGATAQSTLT 9972
Query: 1011 ---------RLEATISPETMRTTKITEGTTQEEFP-WK-----EQTAEK------PV--- 1046
R +T+ P + + T + E P WK E+T+ PV
Sbjct: 9973 LATTTAPLARTHSTVPPRFLHSEMTTLMSRSPENPSWKSSLFVEKTSSSSSLLSLPVTTS 10032
Query: 1047 -----------------------PALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTG 1083
P + T T E T L S ++ E+ T
Sbjct: 10033 PSVSSTLPQSIPSSSFSVTSLLTPGMVKTTDTSTEPGTSLSPNLSGTSVEILAASEVTTD 10092
Query: 1084 SERVPVLETTPVGKIDHSVS----YPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQK 1139
+E++ + V + + S Y ++ K V TP + S+S
Sbjct: 10093 TEKIHPSSSMAVTNVGTTSSGHELYSSVSIHSEPSKATYPVG-TPSSMAETSISTSMPAN 10151
Query: 1140 YETEGSS-------TTGF--------TSSL-------SPFSTHITQLMEE--TTTEKTSL 1175
+ET G T+GF TSS+ SP STH+ Q + T++ KTS
Sbjct: 10152 FETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSSPGSTHLLQSSKTDFTSSAKTSS 10211
Query: 1176 EDIDLGSGLFEKPKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKKPP- 1234
D P A++ E +P DI T F++ + + S+ IT P
Sbjct: 10212 PDW---------PPASQYTE-------IPVDIITPFNA------SPSITESTGITSFPES 10249
Query: 1235 ---LIDREPGEETTSDMVIIGE--STSHVPPTTLEDIVAKETETDIDREYFTTSSPPATQ 1289
+ E ++D++ E ST V P+ E + + T T + R + SP +
Sbjct: 10250 RFTMSVTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFAT-TGVPRAISGSGSPFSRT 10308
Query: 1290 PTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDS 1349
+ P STP P +S+ F + I + E ++ S + +D+
Sbjct: 10309 ESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHE-----ITSSSATPYRVDT 10363
Query: 1350 ESKEDEPCSE-ETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSV 1408
+ +E V L P I + E E T PS+
Sbjct: 10364 SLGTESSTTEGRLVMVSTLDTSSQPGRTSSSPI----LDTRMTESVELGTVTSAYQVPSL 10419
Query: 1409 --QYINGKHLVTTVPKDPEAAEARRGQFESV-APSQNFSDSSESDTHPFVIAKTELSTAV 1465
+ ++ + K P A A RG V P + S +S H + E +T
Sbjct: 10420 STRLTRTDGIMEHITKIPNEA-AHRGTIRPVKGPQTSTSPASPKGLHTGGTKRMETTTTA 10478
Query: 1466 QPNESTETTESLEVTWKPETYPETSEHFSG-----------------GEPDVFPTVPFHE 1508
+T + T Y T + P VFP VP E
Sbjct: 10479 LKTTTTALKTTSRATLTTSVYTPTLGTLTPLNASMQMASTIPTEMMITTPYVFPDVP--E 10536
Query: 1509 EFESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFPEESSGEIAIDQES--QKIAFARAT 1566
S GAE+ T A T P S+F ES ++ S ++ +
Sbjct: 10537 TTSSLATSLGAETST---------ALPRTTP-SVFNRESETTASLVSRSGAERSPVIQTL 10586
Query: 1567 EVTFGEEVEKSTSVTYT----PTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEA 1622
+V+ E ++ V + PT+ ++ + + SE + V+ D+ S + +
Sbjct: 10587 DVSSSEPDTTASWVIHPAETIPTVSKTTPNFFHSELDTVSSTATSHGADVSSAIPTNISP 10646
Query: 1623 TPRQ----VVELSG---SSSIPITEGSGEAEEDEDTMFTMVTDLSQ----------RNTT 1665
+ +V +SG S++ P S E T T + S + +
Sbjct: 10647 SELDALTPLVTISGTDTSTTFPTLTKSPHETETRTTWLTHPAETSSTIPRTIPNFSHHES 10706
Query: 1666 DTLITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKR 1725
D ++ TS E+ +P T+ P +E V + S TD + I + T+ +
Sbjct: 10707 DATPSIATSPG-AETSSAIPIMTVSPGAEDLVTSQVTS---SGTDRNMTIPTLTLSPGEP 10762
Query: 1726 KE--------EEGTTGTASTFEVYSSTQR---SDQLILPFELESPNVATSSDSGTRKSFM 1774
K E T+ T + + R S L + + N A ++ G + +
Sbjct: 10763 KTIASLVTHPEAQTSSAIPTSTISPAVSRLVTSMVTSLAAKTSTTNRALTNSPGEPATTV 10822
Query: 1775 SLTT-PTQSE-----------REMTDSTPVFTETNTLENLGAQTTEHSSIHQPGVQEGLT 1822
SL T P Q+ +D+TP T ++ E+ A T S PGV L
Sbjct: 10823 SLVTHPAQTSPTVPWTTSIFFHSKSDTTPSMTTSHGAESSSAVPTPTVSTEVPGVVTPLV 10882
Query: 1823 TLPRSPASV---FMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEVAGTLSPHVETTFS 1879
T R+ S + GE PETT + S E + P V T+
Sbjct: 10883 TSSRAVISTTIPILTLSPGE----PETTPSMATSHGEEASSAIPTPTVSPGVPGVVTSLV 10938
Query: 1880 TEPTGLVLSTVMDRVVAENITQTSREIVISERL----GEPNYGAEIRGFSTGFPLEEDFS 1935
T + +T+ + +T+ + S P E+ G T
Sbjct: 10939 TSSRAVTSTTIPILTFSLGEPETTPSMATSHGTEAGSAVPTVLPEVPGMVTSLVASSRAV 10998
Query: 1936 GDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVPTSVHISHISDSEGPSSTMVS 1995
+ P E T M S A T + S V S ++ S G +ST +
Sbjct: 10999 TSTTLPTLTLSPGEPETTPSMATSHGAEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSIP 11058
Query: 1996 T---SAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQKFSGTASSIIDEGLGEVGTVN 2052
T S E S A G + +SS VP P+ SG + ++ T
Sbjct: 11059 TLILSPGELETTPSMATSHGAE----ASSAVPT-PTVSPGVSGVVTPLVTSSRAVTSTTI 11113
Query: 2053 EIDRRSTILPTAEVEGTKAPVEKEEVKVSG---TVSTNFPQTIEPAKLWSRQEVNPVRQE 2109
I L ++E E T + V+ S TVS P + SR +
Sbjct: 11114 PI----LTLSSSEPETTPSMATSHGVEASSAVLTVSPEVPGMVTSLVTSSRAVTSTTIPT 11169
Query: 2110 I-----ESETTSEEQIQEEKSFESPQNSPATEQTI--FDSQTFTETELKTTDYSVLTTKK 2162
+ E ETT+ E S + A T+ + T + +T+ +S LT
Sbjct: 11170 LTISSDEPETTTSLVTHSEAKMISAIPTLAVSPTVQGLVTSLVTSSGSETSAFSNLTVAS 11229
Query: 2163 TYSDDKEM-----KEEDTSLV---NMSTPDPDAN------GLESYTTLPEATEK-SHFFL 2207
+ + + E +S+V +ST +P N ES +TLP T + SH L
Sbjct: 11230 SQPETIDSWVAHPGTEASSVVPTLTVSTGEPFTNISLVTHPAESSSTLPRTTSRFSHSEL 11289
Query: 2208 ATALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLP 2267
T T + P + ES+ + P I T L+ S SG ++ T P
Sbjct: 11290 DTMPSTVTSP-----------EAESSSAISTTISPGIPGVLTSLVTS---SGRDISATFP 11335
Query: 2268 T--ESVNFTEV-------EQINNTLYPHT-------------SQVESTSSDKIEDFNRME 2305
T ES + +E + +T P T S S ++ DF +
Sbjct: 11336 TVPESPHESEATASWVTHPAVTSTTVPRTTPNYSHSEPDTTPSIATSPGAEATSDFPTI- 11394
Query: 2306 NVAKEVGPLVSQTDIFEGSGSVTSTTLIEILSDTGAEGPTVAPLPFS---TDIGHPQNQT 2362
V+ +V +V T SG+ TS T+ + +G T + + +S T P
Sbjct: 11395 TVSPDVPDMV--TSQVTSSGTDTSITIPTLTLSSGEPETTTSFITYSETHTSSAIPTLPV 11452
Query: 2363 VRWAEEIQTSRPQTITEQDSNKNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPS 2422
A ++ TS S+ ST T + + A E T P+ +
Sbjct: 11453 SPGASKMLTSL------VISSGTDSTTTFPTLTETPYEPETTAIQLIHPAETNTMVPRTT 11506
Query: 2423 DLYYEPSGEGSGEVDIVDSFHTSATTQATRQESSTTFVSDGSLEKHPEVPSAKAVTADGF 2482
+ + + V I TS +A+ S+TT D S VPS+ T+ F
Sbjct: 11507 PKFSHSKSDTTLPVAI-----TSPGPEASSAVSTTTISPDMSDLVTSLVPSSGTDTSTTF 11561
Query: 2483 PTVS 2486
PT+S
Sbjct: 11562 PTLS 11565
Score = 82.8 bits (203), Expect = 5e-15
Identities = 566/2815 (20%), Positives = 971/2815 (34%), Gaps = 424/2815 (15%)
Query: 415 ITDSLATKLPTPTGSTKKPWDMDDYSPSASGPLGKLDISEIKEEVLQSTTGV--SHYATD 472
ITD L T+L T S D + S D EI + T V ++ +
Sbjct: 5079 ITDILRTRLEPVTSSLPNFSSTSDKILATSKD--SKDTKEIFPSINTEETNVKANNSGHE 5136
Query: 473 SWDGVVEDKQTQESVTQ-IEQIEVGPLVTSMEILKHIPSKEFPVTETP--LVTARMILES 529
S + D +T ++ TQ + VG S + H S+ + P +T R+ S
Sbjct: 5137 SHSPALADSETPKATTQMVITTTVGDPAPSTSMPVHGSSETTNIKREPTYFLTPRLRETS 5196
Query: 530 KTE-------------KKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQI 576
++ K T++E+ +TG + D D++ TV D T +I
Sbjct: 5197 TSQESSFPTDTSFLLSKVPTGTITEVSSTGVNSSSKISTPDHDKS-TVPPDTFT---GEI 5252
Query: 577 PEVITVS---KTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITE 633
P V T S K++E TI T ES S ST +P + +++ + T +T+
Sbjct: 5253 PRVFTSSIKTKSAEMTITTQASPPESASHST------LPLDTSTTLS---QGGTHSTVTQ 5303
Query: 634 EFLGKYLST------------TPFPSQHRTEIELF---PYSGDKILVEGISTVIYPSLQT 678
F ++T T P + + + P V S PS
Sbjct: 5304 GFPYSEVTTLMGMGPGNVSWMTTPPVEETSSVSSLMSSPAMTSPSPVSSTSPQSIPSSPL 5363
Query: 679 EMTHRRERTETLIPEMRTDTYTDEIQEEITKSP--FMGKTEEEVFSGMKLSTSLSEPIHV 736
+T T + TD E +T SP T E + + + + H
Sbjct: 5364 PVT----ALPTSVLVTTTDVLGTTSPESVTSSPPNLSSITHERPATYKDTAHTEAAMHHS 5419
Query: 737 TESSVEM--TKSFDFPTLITKLSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLS 794
T ++V T + + L+ T T+T G T + + + +
Sbjct: 5420 TNTAVTNVGTSGSGHKSQSSVLADSETSKATPLMSTTSTLGDTSVSTSTPNISQTNQIQT 5479
Query: 795 VEAATVSKWSWDEDNTTSKPLESTEPS-ASSKLPPALLTTVGMNGKDKDIPSFTEDGADE 853
A++S E +T+ K +TE + A S +P +T S ++ D
Sbjct: 5480 EPTASLSP-RLRESSTSEKTSSTTETNTAFSYVPTGAITQASRTEISSSRTSISD--LDR 5536
Query: 854 FTLIPDSTQKQLEEV-TDEDIAAHGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITST 912
T+ PD + + + T + + T+ Q TT ++ D++T ST
Sbjct: 5537 PTIAPDISTGMITRLFTSPIMTKSAEMTVTTQTTTPGATSQGILPWDTSTTLFQGGTHST 5596
Query: 913 EGQVYATMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHT 972
Q + E + L D+S T P TS G + +S S T S +
Sbjct: 5597 VSQGFPHSEITTLRSRTPGDVSW--MTTPPVEETSS--GFSLMSPSMTSPSPVSSTSPES 5652
Query: 973 IPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEATISPETMRTT--KITEGT 1030
IP S +P T L+ SV ++ T + T SPE + ++ ++ T
Sbjct: 5653 IPSSPLPVT---ALLTSV---------------LVTTTNVLGTTSPEPVTSSPPNLSSPT 5694
Query: 1031 TQEEFPWKEQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVL 1090
+ +K+ + + A T T + E S S T P+
Sbjct: 5695 QERLTTYKDTAHTEAMHASMHTNTAVANVGTSISGHESQSSVPADSHTSKATS----PMG 5750
Query: 1091 ETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGF 1150
T +G D SVS A E +++T+ +L P + + T+
Sbjct: 5751 ITFAMG--DTSVSTSTPAFFETRIQTESTSSLIPGL----------------RDTRTSEE 5792
Query: 1151 TSSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATELIEF-STIKVTVPSDITT 1209
++++ ST ++++ TTTE + E I P +++ + ST +T S
Sbjct: 5793 INTVTETSTVLSEVPTTTTTEVSRTEVITSSRTTISGPDHSKMSPYISTETITRLSTFPF 5852
Query: 1210 AFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAK 1269
S + + T+ P I++ +D T+S G +H P T +
Sbjct: 5853 VTGSTE-MAITNQTGPIGTISQATLTLD------TSSTASWEG---THSPVTQRFPHSEE 5902
Query: 1270 ETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEV 1329
T + + SPP+ + T P S+P P + H + +
Sbjct: 5903 TTTMSRSTKGVSWQSPPSVEETSSP-------------SSPVPLPAITSHSSLYSAVSGS 5949
Query: 1330 RENKTGRMSDLSVIGH--PIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSE 1387
++ L G ID E + EIL ++ SE
Sbjct: 5950 SPTSALPVTSLLTSGRRKTIDMLDTHSELVTSSLPSASSFSGEILTSEASTNTETIHFSE 6009
Query: 1388 ENEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSS 1447
E T++ TT S+ ++ + + P + E S + S
Sbjct: 6010 NTAE--------TNMGTTNSMHKLHSSVSIHSQPSGHTPPKVTGSMMEDAIVSTSTPGSP 6061
Query: 1448 ES------DTHPFVIAKTELSTAVQPNESTETT--------------ESLEVTWKPETYP 1487
E+ T P E STA+ N +TE+ EVT+ T+
Sbjct: 6062 ETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSVSLDAATEVSRAEVTYYDPTFM 6121
Query: 1488 ETSEHFSGGEPDVFP------------TVPFHEEFESGTAKKGAESVTERDTEVGHQAHE 1535
S S PD+ P T+ H+ + T G S+ + + A
Sbjct: 6122 PASAQ-STKSPDISPEASSSHSNSPPLTISTHKTIATQTGPSGVTSLGQLTLDTSTIATS 6180
Query: 1536 HTEP-----------------------VSLFPEESSGEIAIDQESQKIAFARATEVTFGE 1572
P + P + ++ ++ + + VT
Sbjct: 6181 AGTPSARTQDFVDSETTSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTSTL 6240
Query: 1573 EVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSG 1632
+ E STS + T VP+ A +++ + P +L +T + T + S
Sbjct: 6241 Q-EHSTSSLVSVTSVPTPTLAKITDMDTNLEPVTRSPQNLRNTLATSEATTDTHTMHPSI 6299
Query: 1633 SSSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIYPV 1692
++++ G + FT+ D T ++ TS S ++ + +
Sbjct: 6300 NTAVA---NVGTTSSPNEFYFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMKKI 6356
Query: 1693 SEQPSAKVVPTKFVSETDTSEWI-SSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLI 1751
+ + ++ + ET TS+ I SS+ K T S E+ SS++ S Q
Sbjct: 6357 ESETTFSLIFR--LRETSTSQKIGSSSDTSTVFDKAFTAATTEVSRTELTSSSRTSIQ-- 6412
Query: 1752 LPFELESPNVA--TSSDSGTRKSFMSLTTPTQSEREMTDSTPV-FTETNTLENLGAQTTE 1808
E P ++ TS+ S T S + T ++ T + P T TL + TT
Sbjct: 6413 ---GTEKPTMSPDTSTRSVTMLSTFAGLTKSEERTIATQTGPHRATSQGTLTWDTSITTS 6469
Query: 1809 HSSIHQPGVQEGLTTLPRSP-ASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEVA 1867
+ H + G + L S S E SG + E T+ SS L++ AI + V
Sbjct: 6470 QAGTHS-AMTHGFSQLDLSTLTSRVPEYISGTSPPSVEKTSSSSSLLSLP-AITSPSPVP 6527
Query: 1868 GTLS---PHVETTFSTEPT-GLVLSTVMDRVVAE----------NITQTSREIVISERLG 1913
TL P ++ PT GLV +T M VA I TS +I +E++
Sbjct: 6528 TTLPESRPSSPVHLTSLPTSGLVKTTDMLASVASLPPNLGSTSHKIPTTSEDIKDTEKM- 6586
Query: 1914 EPNYGAEIRGFSTGFPLEEDFSG--DFREYSTVSHPIAKE----ETVM---MEGSGDAAF 1964
P+ + T +E +S + E V+ P+ +T++ M GS +
Sbjct: 6587 YPSTNIAVTNVGTTTSEKESYSSVPAYSEPPKVTSPMVTSFNIRDTIVSTSMPGSSEITR 6646
Query: 1965 RDTQTSPSTVPTSVHISHISDSEGPSSTMVST--SAFPWEEFTSSAEGSGEQLVTVSSSV 2022
+ + ST + + S S+ P +VST SA + T + E S ++ + +
Sbjct: 6647 IEME---STFSLAHGLKGTSTSQDP---IVSTEKSAVLHKLTTGATETSRTEVASSRRTS 6700
Query: 2023 VPVLPSAVQKFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSG 2082
+P P + ++ +I +G + E + I T G+ + G
Sbjct: 6701 IPG-PDHSTESPDISTEVIPSLPISLG-ITESSNMTIITRTGPPLGSTS---------QG 6749
Query: 2083 TVSTNFPQTIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDS 2142
T + + P T A S E+ TT + E S+ P P+ E+T F S
Sbjct: 6750 TFTLDTPTTSSRAGTHSMATQEFPHSEM---TTVMNKDPEILSWTIP---PSIEKTSFSS 6803
Query: 2143 QTFTETELKTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATEK 2202
+ + S K ++ M T + M+T + + ++ P +
Sbjct: 6804 SLMPSPAMTSPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEPTTSSPPNLSST 6863
Query: 2203 SHFFLATALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEV 2262
SH L T T +I A H T + E+T SG GS V
Sbjct: 6864 SHEILTTDEDTTAIEAMHPSTSTAATNVETTS-------------------SGHGSQSSV 6904
Query: 2263 LPTLPTESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFE 2322
L +E T +T+ HT+ V ++ S E + P + +T I +
Sbjct: 6905 L--ADSEKTKATAPMDTTSTM-GHTT-VSTSMSVSSETTKIKRESTYSLTPGLRETSISQ 6960
Query: 2323 GSGSVTSTTLI--EILSDTGAE-GPTVAPLPFSTDIGHPQNQTVRWAEEIQT-------- 2371
+ T T+++ E+ + T AE T T I P TV EI T
Sbjct: 6961 NASFSTDTSIVLSEVPTGTTAEVSRTEVTSSGRTSIPGPSQSTV--LPEISTRTMTRLFA 7018
Query: 2372 ------SRPQTITEQDSNKNSSTAEINETTTSSTDFLARAYG-----FEMAKEFVTSAPK 2420
S TI Q S++ + TS+T A+ + F ++ +
Sbjct: 7019 SPTMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLMSRG 7078
Query: 2421 PSDLYYEPSGEGSGEVDIVDSFHTSATTQATRQESS-TTFVSDGSLEKHPEVPSAKAVTA 2479
P D+ ++ S + ATT S+ +S L + S+ T
Sbjct: 7079 PGDMSWQSSPSLENPSSLPSLLSLPATTSPPPISSTLPVTISSSPLPVTSLLTSSPVTTT 7138
Query: 2480 DGFPTVSVMLPLHSEQNKSSPDPTST----LSNTVSYERSTDGS-----FQDRFREFEDS 2530
D T ++ + + D T +NT + ST+ + E S
Sbjct: 7139 DMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAASNVEIPSSGHESPSS 7198
Query: 2531 TLKPNR-KKPTENIIIDLDKEDKDLILT---------ITESTILEILPELT---SDKNTI 2577
L + K T + I +ED + ++ I + +I + P+L S T
Sbjct: 7199 ALADSETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKESISSLSPKLRETGSSVETS 7258
Query: 2578 IDIDHTKPVYEDILGMQTDID-TEVPSEPHDSNDESNDDSTQVQEIYEAAVNLSLTEETF 2636
I+ + + E +G T+I TEV S S S +ST + EI +
Sbjct: 7259 SAIETSAVLSEVSIGATTEISRTEVTSSSRTSISGS-AESTMLPEISTTRKIIKFPTSPI 7317
Query: 2637 EGSADVLASYTQATHDESMTYEDRSQLDHMGFHFTTGIPA-PSTETELDVLLPTATSLPI 2695
+ + TQ T T E LD T+ P+ T + + LP + +
Sbjct: 7318 LAESSEMTIKTQ-TSPPGSTSESTFTLD------TSTTPSLVITHSTMTQRLPHSEITTL 7370
Query: 2696 PRKSATVIPEIEGIKAEAKALDDMFESSTLSDGQAIADQSEIIPTLGQFERTQEEYEDKK 2755
+ A +P + E + SS LS A+ S + TL
Sbjct: 7371 VSRGAGDVPRPSSLPVE----ETSPPSSQLS-LSAMISPSPVSSTL-------------- 7411
Query: 2756 HAGPSFQPEFSSGAEEALVDHTPYLSIATTHLMDQSVTEVPDVMEGSNPPYYTDTTLAVS 2815
P S + ++ + TT ++D S E S+PP + T++ +
Sbjct: 7412 -------PASSHSSSASVTSLLTPGQVKTTEVLDASAEP-----ETSSPPSLSSTSVEIL 7459
Query: 2816 TFAKLSSQTP-----SSPLTIYSGSEASGHTEIPQPSALPGIDVGSSVMSPQDSFKEIHV 2870
+++++ T S+ G+ +SGH E P S LP + + S + +
Sbjct: 7460 ATSEVTTDTEKIHPFSNTAVTKVGTSSSGH-ESPS-SVLPDSET-TKATSAMGTISIMGD 7516
Query: 2871 NIEATFKPSSEEYLHITEPPSLSPDTKLEPSEDDGKPELLEE-------------MEASP 2917
+T P+ I P+ S T+L + + L E E S
Sbjct: 7517 TSVSTLTPALSNTRKIQSEPASSLTTRLRETSTSEETSLATEANTVLSKVSTGATTEVSR 7576
Query: 2918 TELIAV--------EGTEILQDFQNKTDGQVSG-----EAIKMFPTIKTPEAGTVITTAD 2964
TE I+ E + + QD T ++S E+ KM T +T + + + +
Sbjct: 7577 TEAISFSRTSMSGPEQSTMSQDISIGTIPRISASSVLTESAKMTITTQTGPSESTLESTL 7636
Query: 2965 EIELEGATQW-----------PHSTSASATYGVEAGVVPWLSPQTSERPTLSSSP 3008
+ W PH + + G G V W SP + + SSP
Sbjct: 7637 NLNTATTPSWVETHSIVIQGFPH-PEMTTSMGRGPGGVSWPSPPFVKETSPPSSP 7690
Score = 79.3 bits (194), Expect = 6e-14
Identities = 338/1651 (20%), Positives = 576/1651 (34%), Gaps = 269/1651 (16%)
Query: 534 KMVSTV-SELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVITVSKTSEDTIHT 592
+M ST+ +E++ T Y F E ++G++ ST + P V ++ SE T
Sbjct: 10514 QMASTIPTEMMITTPYVFPDVPETTSSLATSLGAETSTALPRTTPSVF--NRESETT--A 10569
Query: 593 HLEDLESVSASTTVSPLIMPDNNGSSMDDW-----EERQTSGRITEEFLGKYLST-TPFP 646
L S + L + + + W E T + T F L T +
Sbjct: 10570 SLVSRSGAERSPVIQTLDVSSSEPDTTASWVIHPAETIPTVSKTTPNFFHSELDTVSSTA 10629
Query: 647 SQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRERTETLIPEMRTDTYTDEIQEE 706
+ H ++ I T I PS +T L+ TDT T
Sbjct: 10630 TSHGADVS-----------SAIPTNISPSELDALT-------PLVTISGTDTSTTF--PT 10669
Query: 707 ITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMTKSFDF------PTLITKLSAEP 760
+TKSP +T +T L+ P + + +F P++ T AE
Sbjct: 10670 LTKSPHETETR---------TTWLTHPAETSSTIPRTIPNFSHHESDATPSIATSPGAET 10720
Query: 761 TE------VRDMEEDFTATPGTTK-YDENIT--TVLLAHGTLSVEAATVSKWSWDEDNTT 811
+ V ED + T+ D N+T T+ L+ G A+ V+ E T+
Sbjct: 10721 SSAIPIMTVSPGAEDLVTSQVTSSGTDRNMTIPTLTLSPGEPKTIASLVTH---PEAQTS 10777
Query: 812 SKPLESTEPSASSKLPPALLTTVGMNGK--DKDIPSFTEDGADEFTLIPDSTQKQLEEVT 869
S ST A S+L +++T++ ++ + + + A +L+ Q
Sbjct: 10778 SAIPTSTISPAVSRLVTSMVTSLAAKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVPW 10837
Query: 870 DEDIAAHGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPI-----TSTEGQVYATMEGSA 924
I H K TTS G S + T +VP + TS+ + T+
Sbjct: 10838 TTSIFFHSKSDTTPSMTTSHGAESSSAVPTPTVSTEVPGVVTPLVTSSRAVISTTIPILT 10897
Query: 925 LGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSSTQEP------TTYVDSSHTIPLSVI 978
L E T P A TS E + + T P T+ V SS + + I
Sbjct: 10898 LSPGEP-------ETTPSMA-TSHGEEASSAIPTPTVSPGVPGVVTSLVTSSRAVTSTTI 10949
Query: 979 PKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEA-----TISPET--MRTTKI--TEG 1029
P + LGEP + EA T+ PE M T+ + +
Sbjct: 10950 PILTFS------------LGEPETTPSMATSHGTEAGSAVPTVLPEVPGMVTSLVASSRA 10997
Query: 1030 TTQEEFPWKEQTAEKP--VPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERV 1087
T P + +P P+++++ + P E G ++ S +
Sbjct: 10998 VTSTTLPTLTLSPGEPETTPSMATSHGAEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSI 11057
Query: 1088 PVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSST 1147
P L +P G+++ + P T H + V P ++SPG +S+
Sbjct: 11058 PTLILSP-GELETT----PSMATSHGAEASSAV-------PTPTVSPGVSGVVTPLVTSS 11105
Query: 1148 TGFTSSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDI 1207
TS+ P T ++ ETT + ++ S + T+ VP +
Sbjct: 11106 RAVTSTTIPILT-LSSSEPETTPSMATSHGVEASSAVL------------TVSPEVPGMV 11152
Query: 1208 TTAFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGES-------TSHVPP 1260
T+ +S + +T+ P+ I+ P ETT+ +V E+ T V P
Sbjct: 11153 TSLVTSSRAVTSTTI--PTLTISSDEP--------ETTTSLVTHSEAKMISAIPTLAVSP 11202
Query: 1261 TTLEDIVAKETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHP 1320
T + + T + + F+ + ++QP T++ A S+ P +
Sbjct: 11203 TVQGLVTSLVTSSGSETSAFSNLTVASSQPE---TIDSWVAHPGTEASSVVPTLTVS--- 11256
Query: 1321 DINVYIIEVRENKTGR-MSDLSVIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDII 1379
TG +++S++ HP +S S S + D M +
Sbjct: 11257 -------------TGEPFTNISLVTHPAESSSTLPRTTSRFSHSELDTMPSTVTS----- 11298
Query: 1380 EIDLYHSEENEEEEEECANATDVTTTPSVQYI-------NGKHLVTTVPKDPEAAEARRG 1432
E E ++A T +P + + +G+ + T P PE+
Sbjct: 11299 ------------PEAESSSAISTTISPGIPGVLTSLVTSSGRDISATFPTVPESPHESEA 11346
Query: 1433 QFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTETTESLE-VTWKPETYPETSE 1491
V S + T + ++ + + ++ + E T +T P+ +
Sbjct: 11347 TASWVTHPAVTSTTVPRTTPNYSHSEPDTTPSIATSPGAEATSDFPTITVSPDVPDMVTS 11406
Query: 1492 HFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFPEESSGEI 1551
+ D T+P SG + +T +T T PVS + +
Sbjct: 11407 QVTSSGTDTSITIPTLT-LSSGEPETTTSFITYSETHTSSAIP--TLPVSPGASKMLTSL 11463
Query: 1552 AIDQESQKIA-FARATEVTFGEEVEKSTSV--TYTPTIVPSSASAYVSEEEAVTL---IG 1605
I + F TE + E + T T+VP + + + TL I
Sbjct: 11464 VISSGTDSTTTFPTLTETPYEPETTAIQLIHPAETNTMVPRTTPKFSHSKSDTTLPVAIT 11523
Query: 1606 NPWPDDLLSTKESWVEATP------RQVVELSGSSSIPITEGSGEAEEDEDTMFTMVTDL 1659
+P P+ S+ S +P +V SG+ + E + +T T +T
Sbjct: 11524 SPGPE--ASSAVSTTTISPDMSDLVTSLVPSSGTDTSTTFPTLSETPYEPETTATWLTHP 11581
Query: 1660 SQRNTT-------------DTLITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKFV 1706
++ +TT DT ++ TS + ++ VP TTI PS V T V
Sbjct: 11582 AETSTTVSGTIPNFSHRGSDTAPSMVTSPGV-DTRSGVPTTTI-----PPSIPGVVTSQV 11635
Query: 1707 --SETDTSEWISSTTV---EEKKRKEEEGTTGTASTFEVYSSTQRSDQL-ILPFELESPN 1760
S TDTS I + T E + GT + F V T S + + + P
Sbjct: 11636 TSSATDTSTAIPTLTPSPGEPETTASSATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPP 11695
Query: 1761 VATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTETNTLENLGAQTTEHSSIHQPGVQEG 1820
++ S T SF + + T + T + GA S I G
Sbjct: 11696 QTSTPVSRTTSSFSHSSPDATPVMATSPRTEASSAVLTTISPGAPEMVTSQITSSGAATS 11755
Query: 1821 LTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEVAGTLSPHVETT--F 1878
TT+P S M + + + P T T +F + + +E + T+ P ET+
Sbjct: 11756 -TTVPTLTHSPGMPETTALLSTHPRTETSKTFPASTVFPQVSETTASLTIRPGAETSTAL 11814
Query: 1879 STEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPLEEDFSGDF 1938
T+ T + + + +T TSR V P A+ ST E +
Sbjct: 11815 PTQTTSSLFTLL--------VTGTSR--VDLSPTASPGVSAKTAPLSTHPGTE---TSTM 11861
Query: 1939 REYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVPTSVHISHISDSEGPSSTMVSTSA 1998
ST+S + E T ++ S A +T TS T+ S +S +S + +T +
Sbjct: 11862 IPTSTLSLGLL-ETTGLLATSSSA---ETSTSTLTLTVSPAVSGLSSAS--ITTDKPQTV 11915
Query: 1999 FPWEEFTS---SAEGSGEQLVTVSSSVVPVLPSAVQKFSGTASSIIDEGLGEVGTVNEID 2055
W TS ++ G E TV+ + + ++PS + T+ EG+
Sbjct: 11916 TSWNTETSPSVTSVGPPEFSRTVTGTTMTLIPSEMPTPPKTSHG---EGVSP-------- 11964
Query: 2056 RRSTILPTAEVEGTKAPVEKEEVKVSGTVST 2086
+TIL T VE T V+ T +T
Sbjct: 11965 --TTILRTTMVEATNLATTGSSPTVAKTTTT 11993
Score = 77.0 bits (188), Expect = 3e-13
Identities = 504/2548 (19%), Positives = 856/2548 (33%), Gaps = 461/2548 (18%)
Query: 416 TDSLATKLPTPTGSTKKPWDMDDYSPSASGPLGKLDISEIKE--EVLQSTTGVSHYATDS 473
+ S T LP T + + D SPS+ P+ L + + + EVL +++ ++ +
Sbjct: 9726 SSSSLTSLPLTTSLSPVSSTLLDSSPSSPLPVTSLILPGLVKTTEVLDTSSEPKTSSSPN 9785
Query: 474 WDGV-VEDKQTQESVTQIEQIE------VGPLVTSMEILKHIPSKEFPVTETPLVTARMI 526
VE T E +T E+I V + TS + + S +ET + M
Sbjct: 9786 LSSTSVEIPATSEIMTDTEKIHPSSNTAVAKVRTSSSVHES-HSSVLADSETTITIPSMG 9844
Query: 527 LESKTEKKMVSTVS-------ELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEV 579
+ S + V T + + T + T G + T E++ + +P
Sbjct: 9845 ITSAVDDTTVFTSNPAFSETRRIPTEPTFSLTPGFRETSTSEETTSITETSAVLYGVPTS 9904
Query: 580 ITVSKTSEDTIHT---HLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQT-------SG 629
T + + + + H+ D + + S + ++ + SSM + T G
Sbjct: 9905 ATTEVSMTEIMSSNRIHIPDSDQSTMSPDIITEVITRLSSSSMMSESTQMTITTQKSSPG 9964
Query: 630 RITEEFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRERTET 689
+ L +T P H T F +S +L + +
Sbjct: 9965 ATAQSTLTLATTTAPLARTHSTVPPRFLHSE------------MTTLMSRSPENPSWKSS 10012
Query: 690 LIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLS-TSLSEP--IHVTESSVEMTKS 746
L E +T + + + +T SP + T + S TSL P + T++S E S
Sbjct: 10013 LFVE-KTSSSSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKTTDTSTEPGTS 10071
Query: 747 FDFPTLITKLSAEPTEVRDMEEDFTAT----PGTTKYDENITTVLLAHGTLSVEAATVSK 802
L LS E+ E T T P ++ N+ T H S +VS
Sbjct: 10072 -----LSPNLSGTSVEILAASEVTTDTEKIHPSSSMAVTNVGTTSSGHELYS----SVSI 10122
Query: 803 WSWDEDNT--TSKPLESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDS 860
S T P E S S+ +P TT G + + S G + + D+
Sbjct: 10123 HSEPSKATYPVGTPSSMAETSISTSMPANFETT----GFEAEPFSHLTSGFRKTNMSLDT 10178
Query: 861 TQKQLEEVTDEDIAAHGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATM 920
+ + H ++ T T A+ T+ PP
Sbjct: 10179 SSVTPTNTPSSPGSTH---LLQSSKTDFTSSAK-------TSSPDWPP------------ 10216
Query: 921 EGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPK 980
S E+ VD+ P + P S E S+ ++ + +S+H + ++P
Sbjct: 10217 -ASQYTEIP-VDIITPFNASP-----SITESTGITSFPESRFTMSVTESTHHLSTDLLPS 10269
Query: 981 TDW---GVLVPS------------VPSEDEVLGEPSQDILVIDQTRLEATISPETMRTTK 1025
+ G ++PS VP G P +TI+ +T
Sbjct: 10270 AETISTGTVMPSLSEAMTSFATTGVPRAISGSGSPFSRTESGPGDATLSTIAESLPSSTP 10329
Query: 1026 ITEGTTQEEFPWKEQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSE 1085
+ ++ F + + + ++S++ TP T L + V L T S+
Sbjct: 10330 VPFSSST--FTTTDSSTIPALHEITSSSATPYRVDTSLGTESSTTEGRLVMVSTLDTSSQ 10387
Query: 1086 -----RVPVLETTPVGKIDHSV---SYPPGAVTEHKVKTDEVV--------------TLT 1123
P+L+T ++ +Y +++ +TD ++ T+
Sbjct: 10388 PGRTSSSPILDTRMTESVELGTVTSAYQVPSLSTRLTRTDGIMEHITKIPNEAAHRGTIR 10447
Query: 1124 PRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKTSLEDIDLGSG 1183
P GP+ S SP + T G+ T T L TT KT+
Sbjct: 10448 PVKGPQTSTSPASPKGLHTGGTKR---------METTTTALKTTTTALKTT--------- 10489
Query: 1184 LFEKPKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEE 1243
+ T + T+ P + + +S P+ + P + P E
Sbjct: 10490 --SRATLTTSVYTPTLGTLTPLNASMQMASTI---------PTEMMITTPYVFPDVP--E 10536
Query: 1244 TTSDMVI-IGESTSHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTRPPTVEDKEAF 1302
TTS + +G TS P T + +E+ET T S + R P ++ +
Sbjct: 10537 TTSSLATSLGAETSTALPRTTPSVFNRESET-------TASLVSRSGAERSPVIQTLDV- 10588
Query: 1303 GPQALSTPQPPASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESKEDEPCSEETD 1362
+ S P AS HP + + +KT P S+ D S T
Sbjct: 10589 ---SSSEPDTTASWVIHPAETIPTV----SKTT----------PNFFHSELDTVSSTATS 10631
Query: 1363 PVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVTTVPK 1422
D+ + I ++ SE + + TD +TT T+ K
Sbjct: 10632 HGADVSSAI--------PTNISPSELDALTPLVTISGTDTSTT-----------FPTLTK 10672
Query: 1423 DPEAAEARR------GQFESVAPSQ--NFSDSSESDTHPFVIAKTELSTA-------VQP 1467
P E R + S P NFS ESD P + T+ V P
Sbjct: 10673 SPHETETRTTWLTHPAETSSTIPRTIPNFSHH-ESDATPSIATSPGAETSSAIPIMTVSP 10731
Query: 1468 NESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTA-------KKGAE 1520
T + + + S GEP ++ H E ++ +A +
Sbjct: 10732 GAEDLVTSQVTSSGTDRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSAIPTSTISPAVSR 10791
Query: 1521 SVTERDTEVGHQAHEHTEPVSLFPEESSGEIAI----DQESQKIAFARATEVTFGEEVEK 1576
VT T + + ++ P E + +++ Q S + + T + F + +
Sbjct: 10792 LVTSMVTSLAAKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVPWT--TSIFFHSKSDT 10849
Query: 1577 STSVTY-----------TPTI---VPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEA 1622
+ S+T TPT+ VP + V+ AV P +L+ E
Sbjct: 10850 TPSMTTSHGAESSSAVPTPTVSTEVPGVVTPLVTSSRAVISTTIP----ILTLSPGEPET 10905
Query: 1623 TPRQVVELS--GSSSIP-----------ITEGSGEAEEDEDTMFTMVT-DLSQRNTTDTL 1668
TP SS+IP +T + T ++T L + TT ++
Sbjct: 10906 TPSMATSHGEEASSAIPTPTVSPGVPGVVTSLVTSSRAVTSTTIPILTFSLGEPETTPSM 10965
Query: 1669 IT---LDTSRIITESFFEVPA--TTIYPVSEQPSAKVVPTKFVS----ETDTSEWIS--- 1716
T + + EVP T++ S ++ +PT +S ET S S
Sbjct: 10966 ATSHGTEAGSAVPTVLPEVPGMVTSLVASSRAVTSTTLPTLTLSPGEPETTPSMATSHGA 11025
Query: 1717 --STTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELES-PNVATSSDSGTRKSF 1773
S+TV + T ++ +ST ++ P ELE+ P++ATS + ++
Sbjct: 11026 EASSTVPTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGA---EAS 11082
Query: 1774 MSLTTPTQSEREMTDSTPVFTETN----------TLENLGAQTTEHSSIHQPGVQEGLTT 1823
++ TPT S TP+ T + TL + +TT S GV+
Sbjct: 11083 SAVPTPTVSPGVSGVVTPLVTSSRAVTSTTIPILTLSSSEPETTP-SMATSHGVEASSAV 11141
Query: 1824 LPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEVAGTLSPHVETTFSTEPT 1883
L SP M ++ +TT+ + +++ + E E +L H E +
Sbjct: 11142 LTVSPEVPGMVTSLVTSSRAVTSTTIPTLTISSD-----EPETTTSLVTHSEAKMISAIP 11196
Query: 1884 GLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPLEEDFS-------- 1935
L +S + +V +T + E L + E P E S
Sbjct: 11197 TLAVSPTVQGLVTSLVTSSGSETSAFSNLTVASSQPETIDSWVAHPGTEASSVVPTLTVS 11256
Query: 1936 --GDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVPTSVHISHISDSEGPSSTM 1993
F S V+HP A+ + + + + + T PSTV + E SS+
Sbjct: 11257 TGEPFTNISLVTHP-AESSSTLPRTTSRFSHSELDTMPSTV---------TSPEAESSSA 11306
Query: 1994 VSTSAFPWEE--FTSSAEGSGEQLVTVSSSVVPVLPSAVQKFSGTASSIIDEGLGEVGTV 2051
+ST+ P TS SG + S+ P +P + + TAS + +
Sbjct: 11307 ISTTISPGIPGVLTSLVTSSGRDI----SATFPTVPESPHESEATASWVTHPAVTSTTVP 11362
Query: 2052 NEIDRRSTILP-TAEVEGTKAPVEKEEVKVSGTVSTNFPQTIEPAKLWSRQEVNPVRQEI 2110
S P T T E + TVS + P + S + + +
Sbjct: 11363 RTTPNYSHSEPDTTPSIATSPGAEATSDFPTITVSPDVPDMVTSQVTSSGTDTSITIPTL 11422
Query: 2111 -----ESETTSE----EQIQEEKSFESPQNSPATEQTIFDSQTFTETELKTTDYSVLTTK 2161
E ETT+ + + + SP + + + T+ TT + LT
Sbjct: 11423 TLSSGEPETTTSFITYSETHTSSAIPTLPVSPGASKMLTSLVISSGTD-STTTFPTLT-- 11479
Query: 2162 KTYSDDKEMKEEDTSLVNMSTPDPDANGLESYTTLPEATEKSHFFLATALVTESIPAEHV 2221
+ E +T+ + + P + N + TT + KS L A+ + A
Sbjct: 11480 ------ETPYEPETTAIQLIHP-AETNTMVPRTTPKFSHSKSDTTLPVAITSPGPEASSA 11532
Query: 2222 VTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLPTESVNFTEVEQINN 2281
V+ + I P + + T L+ S SG + T PT S E E
Sbjct: 11533 VSTTTIS-------------PDMSDLVTSLVPS---SGTDTSTTFPTLSETPYEPET-TA 11575
Query: 2282 TLYPHTSQVESTSSDKIEDFNRMENVAKEVGP-LVSQTDIFEGSGSVTSTTLIEI----- 2335
T H ++ +T S I +F+ + P +V+ + SG T+T I
Sbjct: 11576 TWLTHPAETSTTVSGTIPNFSHR---GSDTAPSMVTSPGVDTRSGVPTTTIPPSIPGVVT 11632
Query: 2336 ------LSDTGAEGPTVAPLP-----FSTDIGHPQNQTVRWA--EEIQTSRPQTITEQDS 2382
+DT PT+ P P ++ HP QT + +S P T+ +
Sbjct: 11633 SQVTSSATDTSTAIPTLTPSPGEPETTASSATHPGTQTGFTVPIRTVPSSEPDTMASWVT 11692
Query: 2383 NKNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPSDLYYEPSGEGSGEVDIVDSF 2442
+ ++ ++ TT+S + A MA T A P I S
Sbjct: 11693 HPPQTSTPVSRTTSSFSHSSPDATPV-MATSPRTEASSAVLTTISPGAPEMVTSQITSSG 11751
Query: 2443 HTSATTQATRQESSTTFVSDGSLEKHPEVPSAKAVTADG-FPTVS---VMLPLHSEQNKS 2498
++TT T S + L HP ++K A FP VS L + S
Sbjct: 11752 AATSTTVPTLTHSPGMPETTALLSTHPRTETSKTFPASTVFPQVSETTASLTIRPGAETS 11811
Query: 2499 SPDPTST----------------LSNTVSYERSTDGSFQDRFREFEDSTLKPNRK----- 2537
+ PT T LS T S S + E ST+ P
Sbjct: 11812 TALPTQTTSSLFTLLVTGTSRVDLSPTASPGVSAKTAPLSTHPGTETSTMIPTSTLSLGL 11871
Query: 2538 -KPTENIIIDLDKEDKDLILTITESTILEILPE--LTSDKNTIIDIDHTK---------- 2584
+ T + E LT+T S + L +T+DK + +T+
Sbjct: 11872 LETTGLLATSSSAETSTSTLTLTVSPAVSGLSSASITTDKPQTVTSWNTETSPSVTSVGP 11931
Query: 2585 PVYEDILG--MQTDIDTEVPSEPHDSNDESNDDSTQVQEIYEAAVNLSLTEETFEGSADV 2642
P + + T I +E+P+ P S+ E +T ++ A NL+ T GS+
Sbjct: 11932 PEFSRTVTGTTMTLIPSEMPTPPKTSHGEGVSPTTILRTTMVEATNLATT-----GSSPT 11986
Query: 2643 LASYTQATH-------------------DESMTYEDRSQLDHMGFHFTTG-------IPA 2676
+A T + ES+T R+ +H + TT PA
Sbjct: 11987 VAKTTTTFNTLAGSLFTPLTTPGMSTLASESVT--SRTSYNHRSWISTTSSYNRRYWTPA 12044
Query: 2677 PSTETELDVLLPTATSLPIPRKSATVIP 2704
ST P ++ IP +A +P
Sbjct: 12045 TSTPV-TSTFSPGISTSSIPSSTAATVP 12071
Score = 73.9 bits (180), Expect = 2e-12
Identities = 399/1984 (20%), Positives = 692/1984 (34%), Gaps = 304/1984 (15%)
Query: 672 IYPSLQTEMTHRRERTETLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLS 731
I+P + T +H ++E +R T Q +S +G+T + L+T
Sbjct: 1488 IFPPMSTP-SHELSKSEADTSAIRNTDSTTLDQHLGIRS--LGRTGD-------LTTVPI 1537
Query: 732 EPIHVTESSVEMTKSFDFPTLITKLSAEPTEVRDMEEDFTATPGTTKYDENITTV---LL 788
P+ T +SV + TL +S PT V +D T+ P + ++T V L
Sbjct: 1538 TPLTTTWTSVIEHSTQAQDTLSATMS--PTHVTQSLKDQTSIPASAS-PSHLTEVYPELG 1594
Query: 789 AHGTLSVEAATVSKWSWDEDNTTSKPLESTEPSASSKLPPALLTTVGMNGKDKDIPSFTE 848
G S EA T K S D T S+ +E T P+ PP TT G + +
Sbjct: 1595 TQGRSSSEATTFWKPSTD---TLSREIE-TGPTNIQSTPPMDNTTTGSSSSGVTLG---- 1646
Query: 849 DGADEFTLIPDSTQKQLEEVTDEDIAAHGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPP 908
+P T E T+ + + +T+T ++ T+ T
Sbjct: 1647 -----IAHLPIGTSSPAETSTN--------MALERRSSTAT-VSMAGTMGLLVTSAPGRS 1692
Query: 909 ITSTEGQVYATMEGSALGEVEDVDL--SKPVSTVPQFAHTSEVE-GLAFVSYSSTQEPTT 965
I+ + G+V + + S V D S ++T A +S +E A S ST P T
Sbjct: 1693 ISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMSTSIPLT 1752
Query: 966 YVDSSHTIP--LSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEATISPETMRT 1023
SS T P + T W V +V + D I ++ S T+ +
Sbjct: 1753 ---SSPTTPDVEFIGGSTFWTKEVTTVMTSD------------ISKSSARTESSSATLMS 1797
Query: 1024 TKI--TEGTTQEEFPWKEQTAEKPVPALSSTAW------TPKEAVTPLDEQEG--DGSAY 1073
T + TE T +E+ P P++ T W LD G SA
Sbjct: 1798 TALGSTENTGKEKLRTASMDLPSPTPSMEVTPWISLTLSNAPNTTDSLDLSHGVHTSSAG 1857
Query: 1074 TVSEDELL-TGSERVPVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSL 1132
T++ D L TG R LE G S S G T + T T + S+
Sbjct: 1858 TLATDRSLNTGVTRASRLEN---GSDTSSKSLSMGNSTHTSM------TYTEKSEVSSSI 1908
Query: 1133 SPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATE 1192
P PE G+ TT TS+ + +T E+ I G + P
Sbjct: 1909 HPRPETS--APGAETT-LTSTPGNRAISLTLPFSSIPVEEVISTGITSGPDINSAPMTHS 1965
Query: 1193 LIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKKPPLIDREP--GEETTSDMVI 1250
I TI T I S LH S+ K S T+ P ++ T + V
Sbjct: 1966 PITPPTIVWTSTGTIE---QSTQPLHAVSSEKVSVQ-TQSTPYVNSVAVSASPTHENSVS 2021
Query: 1251 IGESTSHVPPT----TLEDIVAKETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQA 1306
G STS + +L+ +++ TTS P T P+ ++ + + G
Sbjct: 2022 SGSSTSSPYSSASLESLDSTISRRNAITSWLWDLTTSLPTTTWPST--SLSEALSSGHSG 2079
Query: 1307 LSTPQPPASTKF--HPDINVYIIEVRENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPV 1364
+S P +T+F + + R +T + +++++ SE PV
Sbjct: 2080 VSNPSS-TTTEFPLFSAASTSAAKQRNPETETHGPQNTAASTLNTDASSVTGLSET--PV 2136
Query: 1365 HDLMAEILPEFPDII----EIDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVT-T 1419
++ +P P I ++ SE A++ T ++ + LV+
Sbjct: 2137 GASISSEVP-LPMAITSRSDVSGLTSESTANPSLGTASSAGTKLTRTISLPTSESLVSFR 2195
Query: 1420 VPKDPEAAEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTETTESLEV 1479
+ KDP G + + +S +A + T P++ E+ ++
Sbjct: 2196 MNKDPWTVSIPLGSHPTTNTETSIPVNSAGPPGLSTVASDVIDT---PSDGAESIPTVSF 2252
Query: 1480 TWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQAHEHTEP 1539
+ P+T T HF E T + HE T
Sbjct: 2253 SPSPDTEVTTISHFP-------------------------EKTTHSFRTISSLTHELTSR 2287
Query: 1540 VSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSASAYVSEEE 1599
V+ P G+ S K A + +T GE + T + PT P +A +E
Sbjct: 2288 VTPIP----GDWMSSAMSTKPTGA-SPSITLGE---RRTITSAAPTTSPIVLTASFTETS 2339
Query: 1600 AVTLIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDTMFTMVTDL 1659
V+L D+ + K S +++ ++ +P ++ D + T +
Sbjct: 2340 TVSL------DNETTVKTS-------DILDARKTNELP-----SDSSSSSDLINTSIA-- 2379
Query: 1660 SQRNTTDTLITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTT 1719
+ T+ T+ I S + A++ + +V + + T TS +SS T
Sbjct: 2380 -----SSTMDVTKTASISPTSISGMTASSSPSLFSSDRPQVPTSTTETNTATSPSVSSNT 2434
Query: 1720 VEEKKRKEEEGTTGTASTFEVYSSTQRSDQLIL---PFELESPNVATSSDSG---TRKSF 1773
GT T F + + S L+ P S V+T + SG T +
Sbjct: 2435 YSLDGGSNVGGTPSTLPPFTITHPVETSSALLAWSRPVRTFSTMVSTDTASGENPTSSNS 2494
Query: 1774 MSLTTPTQSEREMTDSTPVFTETNTLE--------NLGAQTTEHSSIHQPGVQEGLTT-- 1823
+ + P ST L+ +L A T E ++ P + + T
Sbjct: 2495 VVTSVPAPGTWTSVGSTTDLPAMGFLKTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGS 2554
Query: 1824 LPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEVAGTLSPHVETT------ 1877
S AS+ S + P+T T + N E + E + T + T
Sbjct: 2555 SATSEASLLTTSESKAIHSSPQTPTTPTSGANWETSATPESLLVVTETSDTTLTSKILVT 2614
Query: 1878 ----FSTEPT------------GLVLSTVMDRVVAENITQTSREIVISERLGEP---NYG 1918
FST T G T++ A +T T ++
Sbjct: 2615 DTILFSTVSTPPSKFPSTGTLSGASFPTLLPDTPAIPLTATEPTSSLATSFDSTPLVTIA 2674
Query: 1919 AEIRGF--STGFPLEEDFSGDFREYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVPT 1976
++ G T + E +GD TVS+P + ++G ++ + TSPS +
Sbjct: 2675 SDSLGTVPETTLTMSETSNGDALVLKTVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVA 2734
Query: 1977 SVHISHISDSEGPSSTMVSTSAFPWEE-----FTSSAEGSGEQLVTVSSSVVPVLPSAVQ 2031
+ ++ EG S V+ S P F+ S+E S E V SS + ++
Sbjct: 2735 PRNTTY----EG--SITVALSTLPAGTTGSLVFSQSSENS-ETTALVDSS------AGLE 2781
Query: 2032 KFSGTASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQT 2091
+ S + +G+ G + ST GTK ++ P T
Sbjct: 2782 RASVMPLTTGSQGMASSGGIRSGSTHST--------GTK-------------TFSSLPLT 2820
Query: 2092 IEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQTFTETELK 2151
+ P ++ + E+ R T + + S ES +P + + S+ F
Sbjct: 2821 MNPGEVTAMSEITTNRLTATQSTAPKGIPVKPTSAESGLLTPVSASS-SPSKAFASLTTA 2879
Query: 2152 TTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPD------PDANGLESYTTL---PEATEK 2202
+ + + T+ + E+ DT ++ TP PD++ + ++L PE +
Sbjct: 2880 PPTWGIPQSTLTF-EFSEVPSLDTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEKNPR 2938
Query: 2203 SHFFLATALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEV 2262
+ +T ++ S T++P E S G P + S G+G+
Sbjct: 2939 ARMMTSTKAISASSFQSTGFTETP---EGSASPSMAGHEPRVPTS---------GTGD-- 2984
Query: 2263 LPTLPTESVNFTEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFE 2322
P +ES+++ + + ++ + + + T+ R + + + + F
Sbjct: 2985 -PRYASESMSYPDPSKASSAMTSTSLASKLTTLFSTGQAARSGSSSSPISLSTEKETSFL 3043
Query: 2323 GSGSVTSTTLIEILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEE--IQTSRPQTITEQ 2380
+ TS L + A P + ++ + T+ ++E + + QTI E+
Sbjct: 3044 SPTASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTSTLNMSQEEPPELTSSQTIAEE 3103
Query: 2381 DSNKNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPSDLYYEPSGEGSGEVDIVD 2440
+ +TAE T + ++ E T+ K S + S + +V+
Sbjct: 3104 E----GTTAETQTLTFTPSETPTSLLPVSSPTE-PTARRKSSPETWASSISVPAKTSLVE 3158
Query: 2441 SFHTSATTQATRQESSTTFVSDGSLEKHP--EVPSAKAVTADGFPTVSVMLPLHSEQNKS 2498
T+ T T + S+ S P E S+ A T+ G P +S L + S + S
Sbjct: 3159 ---TTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAGTSPGSPEMSTTLKIMSSKEPS 3215
Query: 2499 -SPDPTSTLSNT-----------------VSYERSTDGSFQDRFREFEDSTLKPNRKKPT 2540
SP+ ST+ N+ V+ + + GS T P K PT
Sbjct: 3216 ISPEIRSTVRNSPWKTPETTVPMETTVEPVTLQSTALGSGSTSISHLPTGTTSPT-KSPT 3274
Query: 2541 ENII 2544
EN++
Sbjct: 3275 ENML 3278
Score = 72.0 bits (175), Expect = 9e-12
Identities = 473/2380 (19%), Positives = 798/2380 (33%), Gaps = 429/2380 (18%)
Query: 742 EMTKSFDF---PTLITKLSAEPTEVRDME-----EDFTATPGTTKYDENITTVLLAHGTL 793
+ T +F+F P+L TK ++ PT + + + TA+ +K E + T
Sbjct: 2887 QSTLTFEFSEVPSLDTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEKNPRARMMTSTK 2946
Query: 794 SVEAATVSKWSWDEDNTTSKPLESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADE 853
++ A+ S+ T P S PS + P + G + S+ +
Sbjct: 2947 AISAS-----SFQSTGFTETPEGSASPSMAGHEPRVPTSGTGDPRYASESMSYPDPSKAS 3001
Query: 854 FTLIPDSTQKQLEEVTDEDIAAHGKFT---IRFQPTTSTGIAEKSTLRDSTTEEKVPPIT 910
+ S +L + AA + I T + T + P
Sbjct: 3002 SAMTSTSLASKLTTLFSTGQAARSGSSSSPISLSTEKETSFLSPTASTSRKTSLFLGPSM 3061
Query: 911 STEGQVYATMEGSALGEVEDVDLSKPVSTVPQFAHT---SEVEGLAFVSYSSTQEPTTYV 967
+ + + ++ SAL L+ P+ + +E EG +T E T
Sbjct: 3062 ARQPNILVHLQTSALTLSPTSTLNMSQEEPPELTSSQTIAEEEG-------TTAETQTLT 3114
Query: 968 DSSHTIPLSVIPKTDWGVLVPSVPSEDEVLGEPSQD-----ILVIDQTRLEATISPETMR 1022
+ P S++P S P+E + S + I V +T L T +
Sbjct: 3115 FTPSETPTSLLPV--------SSPTEPTARRKSSPETWASSISVPAKTSLVETTDGTLVT 3166
Query: 1023 TTKITEGTTQEEFPWK---EQTAEKPV------PALSSTA--WTPKE-AVTPLDEQEGDG 1070
T K++ Q W E+T P P +S+T + KE +++P
Sbjct: 3167 TIKMSSQAAQGNSTWPAPAEETGSSPAGTSPGSPEMSTTLKIMSSKEPSISPEIRSTVRN 3226
Query: 1071 SAYTVSEDELLTGSERVPV-LETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPK 1129
S + E + + PV L++T +G S+S+ P T E + T R
Sbjct: 3227 SPWKTPETTVPMETTVEPVTLQSTALGSGSTSISHLPTGTTSPTKSPTENMLATER---- 3282
Query: 1130 VSLSPGPEQKYETEGSSTTGFT----------SSLSPFSTHITQLMEETTTE---KTSLE 1176
VSLSP P + + S T G T S SP + IT ++++ E KT+
Sbjct: 3283 VSLSPSPPEAWTNLYSGTPGGTRQSLATMSSVSLESPTARSITGTGQQSSPELVSKTTGM 3342
Query: 1177 DIDLGSGLFEKPKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKKPPLI 1236
+ + G + ST + D T+ +SV L S K + +
Sbjct: 3343 EFSMWHGSTGGTTGDTHVSLSTSS-NILEDPVTSPNSVSSLTDKSKHKTETWV------- 3394
Query: 1237 DREPGEETTSDMVIIGESTSHVPPTTLED-IVAKETETD--IDREYFTTSSPPATQPTRP 1293
ST+ +P T L + I+A E +T +D Y +TSS
Sbjct: 3395 -----------------STTAIPSTVLNNKIMAAEQQTSRSVDEAYSSTSS--------- 3428
Query: 1294 PTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESKE 1353
+ G P + + + +G ++ + +P ++
Sbjct: 3429 ---WSDQTSGSDITLGASPDVTNTLYITSTAQTTSLVSLPSGDQG-ITSLTNPSGGKTSS 3484
Query: 1354 DEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYIN- 1412
+ + + L A + DI + S+ + E + DVTT P+
Sbjct: 3485 ASSVTSPSIGLETLRANVSAVKSDIAPTAGHLSQTSSPAE---VSILDVTTAPTPGISTT 3541
Query: 1413 ----GKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPN 1468
G + ++T +PE + +S ++ + S+E HP T STA +
Sbjct: 3542 ITTMGTNSISTTTPNPEVGMST---MDSTPATERRTTSTE---HP----STWSSTAASDS 3591
Query: 1469 ES-TETTESLEVTWKP---ETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTE 1524
+ T+ T +L+V P T TS S E D T G VT
Sbjct: 3592 WTVTDMTSNLKVARSPGTISTMHTTSFLASSTELDSMSTP------HGRITVIGTSLVTP 3645
Query: 1525 RDTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTP 1584
+ T +L P +++ I F+R ++ STS T
Sbjct: 3646 SSDASAVKTETSTSERTLSPSDTTASTPIS------TFSRVQRMSISVPDILSTSWT--- 3696
Query: 1585 TIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGE 1644
PSS A E+ V+++ D STK TP S++ G
Sbjct: 3697 ---PSSTEA---EDVPVSMVST----DHASTKTD--PNTPLSTFLFDSLSTLDWDTGRSL 3744
Query: 1645 AEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIYPVSEQPSAKVV--- 1701
+ T Q T +T+I+ TS++ A T P + S+ V
Sbjct: 3745 SSATATTSAPQGATTPQELTLETMISPATSQLPFSIGHITSAVT--PAAMARSSGVTFSR 3802
Query: 1702 --PTKFVSETDTSEWISSTTVEEKKRKEEEGTT-----GTASTFEVYSSTQRSDQLILPF 1754
PT +E +++ ++T+ + TT TA T + ++ QR Q L
Sbjct: 3803 PDPTSKKAEQTSTQLPTTTSAHPGQVPRSAATTLDVIPHTAKTPD--ATFQRQGQTALTT 3860
Query: 1755 ELESPNVATSSDSGTRKSFMSLTTPTQSE----------REMTDSTPVFTETNTLENLGA 1804
E + +SDS K + + P +E +E+T S+ V NTL+
Sbjct: 3861 EARA-----TSDSWNEKEKSTPSAPWITEMMNSVSEDTIKEVTSSSSVLRTLNTLDI--- 3912
Query: 1805 QTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVE-YAIQAE 1863
++ G T+ P +S + E+ D E S+ ++ + +E
Sbjct: 3913 -----------NLESGTTSSPSWKSSPYERIAPSESTTDKEAIHPSTNTVETTGWVTSSE 3961
Query: 1864 KEVAGTLSPHVETTFSTEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRG 1923
T+ H ++ T P +V ++ ++ + T T E + EPN I
Sbjct: 3962 HASHSTIPAHSASSKLTSP--VVTTSTREQAIVSMSTTTWPESTRART--EPNSFLTI-- 4015
Query: 1924 FSTGFPLEEDFSGDFREYSTVSHPIAKEETVMMEGSGDAAF----RDTQTSPSTVPTSVH 1979
+ R+ S + +T ++ G A R TS + +S
Sbjct: 4016 -------------ELRDVSPYMDTSSTTQTSIISSPGSTAITKGPRTEITSSKRISSSFL 4062
Query: 1980 ISHISDSEGPSSTMVSTSAFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQKFSGTASS 2039
+ S+ PS + S FP + E G L +S SA + +S
Sbjct: 4063 AQSMRSSDSPSEAITRLSNFP-----AMTESGGMILAMQTSPPGATSLSAPTLDTSATAS 4117
Query: 2040 IIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTV----STNFPQTIE-P 2094
L ++ + E +P EE S ++ +T P I
Sbjct: 4118 WTGTPLATTQRFTYSEKTTLFSKGPEDTSQPSPPSVEETSSSSSLVPIHATTSPSNILLT 4177
Query: 2095 AKLWSRQEVNPVRQEIESET------TSEEQIQEEKSFESPQNSPATEQTIFDSQTFTET 2148
++ S PV SET T +I E P N
Sbjct: 4178 SQGHSPSSTPPVTSVFLSETSGLGKTTDMSRISLEPGTSLPPN----------------- 4220
Query: 2149 ELKTTDYSVLTTKKTYSDDKEMKEE-DTSLVNMSTPDPDANGLESYTTLPEATEKSHFFL 2207
L +T L+T + D K + DT++ NM + + + +T +AT
Sbjct: 4221 -LSSTAGEALSTYEASRDTKAIHHSADTAVTNMEATSSEYSPIPGHTKPSKAT------- 4272
Query: 2208 ATALVTESIPAEHVVTDSPIKKEESTK-HFPKGMRPTIQESDTELLFSGLGSGEEVLPTL 2266
+ LVT I + + S E+T+ + +QE T +V +
Sbjct: 4273 -SPLVTSHIMGDITSSTSVFGSSETTEIETVSSVNQGLQERSTS----------QVASSA 4321
Query: 2267 PTESVNFTEVEQINNTLYPHTSQVESTSSDKIED---FNRMENVAKEVGPLVSQTDIFEG 2323
S T V + T + +Q +S I F N +V S + I
Sbjct: 4322 TETSTVITHVSSGDATTHVTKTQATFSSGTSISSPHQFITSTNTFTDVSTNPSTSLIMTE 4381
Query: 2324 SGSVTSTTLIEILSDTGA--EGP-----------TVAPLPFSTDIGHPQNQT-------- 2362
S VT TT TGA +GP T PL + D + T
Sbjct: 4382 SSGVTITTQT---GPTGAATQGPYLLDTSTMPYLTETPLAVTPDFMQSEKTTLISKGPKD 4438
Query: 2363 VRWAEE---IQTSRPQTIT----------------EQDSNKNSSTAEINETTTSSTDFLA 2403
V W +TS P ++T + S+ S+T+ + +TD L
Sbjct: 4439 VSWTSPPSVAETSYPSSLTPFLVTTIPPATSTLQGQHTSSPVSATSVLTSGLVKTTDML- 4497
Query: 2404 RAYGFEMAKEFVTSAPKPSDLYYEPSGE------GSGEVDIVDSFHTSATTQATRQESST 2457
+ E VT++P+ + PS E + +++ + A T S+
Sbjct: 4498 -----NTSMEPVTNSPQNLN---NPSNEILATLAATTDIETIHPSINKAVTNMGTASSAH 4549
Query: 2458 TFVSDGSLEKHPEVPSAKAVTAD--GFPTVSVMLPLHSEQNKSSPDPTSTLSNTVSYERS 2515
S + P ++ V A G S+ +P SE +PTS+L
Sbjct: 4550 VLHSTLPVSSEPSTATSPMVPASSMGDALASISIP-GSETTDIEGEPTSSL--------- 4599
Query: 2516 TDGSFQDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDLILTITESTILEILPELTSDKN 2575
T G E+STL+ NII+ + ITE+T +E+ S
Sbjct: 4600 TAG-------RKENSTLQEMNSTTESNIILS-----NVSVGAITEATKMEV----PSFDA 4643
Query: 2576 TIIDIDHTKPVYEDILGMQTDIDTEVPS---EPHDSNDESNDDSTQVQEIYEAAVNLSLT 2632
T I + DI + + + P H + ++ + + L+L
Sbjct: 4644 TFIPTPAQSTKFPDIFSVASSRLSNSPPMTISTHMTTTQTGSSGAT------SKIPLALD 4697
Query: 2633 EETFEGSADVLASYTQATHDESMTY---EDRSQLDHMGFHFTTGIPAPSTETELDVL-LP 2688
T E SA + T+ +T D + F +PS++ + V LP
Sbjct: 4698 TSTLETSAGTPSVVTEGFAHSKITTAMNNDVKDVSQTNPPFQDEASSPSSQAPVLVTTLP 4757
Query: 2689 TA---------TSLPIPRKSATVIPEIEGIKAEAKALDDMFESSTLSDGQAIADQSEIIP 2739
++ TS P+ S + A +D E+ T S Q++++
Sbjct: 4758 SSVAFTPQWHSTSSPVSMSSVLT----SSLVKTAGKVDTSLETVT-SSPQSMSN------ 4806
Query: 2740 TLGQFERTQEEYEDKKHAGPSFQPEFSSGAEEALVDHTPYLSIATTHLMDQSVTEVPDVM 2799
TL T D + PS +T ++ TT +S + V
Sbjct: 4807 TLDDISVTSAATTDIETTHPSI--------------NTVVTNVGTTGSAFESHSTVSAYP 4852
Query: 2800 EGSN--PPYYTDTTLAVSTFAKLSSQTPSSPLTIYSGSEASGHTEIPQPSALPGIDVGSS 2857
E S P T +T+ +T +S P S T + +E + ++ SS
Sbjct: 4853 EPSKVTSPNVTTSTMEDTT---ISRSIPKSSKTTRTETETTSSLTPKLRETSISQEITSS 4909
Query: 2858 VMSPQDSFKEIHVNIEATFKPSSEEYLHITEPPSLSPDTKLEPSEDDGKPELLEEMEASP 2917
+ +KE+ AT + S + + PD D E + SP
Sbjct: 4910 TETSTVPYKEL---TGATTEVSRTDVTSSSSTSFPGPDQSTVSL--DISTETNTRLSTSP 4964
Query: 2918 TELIAVEGTEILQDFQNKTDGQVSGEAIKMFPTIKTPEAG 2957
I E EI Q G S + M P+ TP+AG
Sbjct: 4965 ---IMTESAEITITTQTGPHGATSQDTFTMDPSNTTPQAG 5001
Score = 67.0 bits (162), Expect = 3e-10
Identities = 505/2555 (19%), Positives = 871/2555 (34%), Gaps = 343/2555 (13%)
Query: 666 EGISTVIY-PSLQTEMTHRRERTETLIPEMRT-DTYTDEIQEEITKSP--FMGKTEEEVF 721
E I TV + PS TE+T E RT + T E+ +T P +M
Sbjct: 2245 ESIPTVSFSPSPDTEVTTISHFPEKTTHSFRTISSLTHELTSRVTPIPGDWMSSAMSTKP 2304
Query: 722 SGMKLSTSLSEPIHVTE-----SSVEMTKSFDFPTLIT---KLSAEPTEVRDMEEDFTAT 773
+G S +L E +T S + +T SF + ++ + + + +++ D +
Sbjct: 2305 TGASPSITLGERRTITSAAPTTSPIVLTASFTETSTVSLDNETTVKTSDILDARKT-NEL 2363
Query: 774 PGTTKYDENITTVLLAHGTLSV-EAATVSKWSWDEDNTTSKP--LESTEPSA-SSKLPPA 829
P + ++ +A T+ V + A++S S +S P S P +S
Sbjct: 2364 PSDSSSSSDLINTSIASSTMDVTKTASISPTSISGMTASSSPSLFSSDRPQVPTSTTETN 2423
Query: 830 LLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDEDIAAHGKFTIRFQPTTST 889
T+ ++ + + G TL P + +E T + A + F ST
Sbjct: 2424 TATSPSVSSNTYSLDGGSNVGGTPSTLPPFTITHPVE--TSSALLAWSRPVRTFSTMVST 2481
Query: 890 GIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSKPVSTV-----PQFA 944
A S + P T V +T + A+G ++ + S + P A
Sbjct: 2482 DTASGENPTSSNSVVTSVPAPGTWTSVGSTTDLPAMGFLKTSPAGEAHSLLASTIEPATA 2541
Query: 945 HTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDI 1004
T + S+T E + + +S + + P+T P+ + E P + +
Sbjct: 2542 FTPHLSAAVVTGSSATSE-ASLLTTSESKAIHSSPQTP---TTPTSGANWETSATP-ESL 2596
Query: 1005 LVIDQTRLEATISPETMRTTKI---TEGTTQEEFPWKEQTAEKPVPALSSTAWTPKEAVT 1061
LV+ +T + T++ + + T I T T +FP + P L P
Sbjct: 2597 LVVTETS-DTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFPTL-----LPDTPAI 2650
Query: 1062 PLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVT 1121
PL E S L T + P++ D + P +T + + +
Sbjct: 2651 PLTATEPTSS--------LATSFDSTPLVTIAS----DSLGTVPETTLTMSETSNGDALV 2698
Query: 1122 LTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKTSLEDIDLG 1181
L P S+ PG + TE S L P ST ++++ T + L
Sbjct: 2699 LKTVSNPDRSI-PGITIQGVTE--------SPLHPSSTSPSKIVAPRNTTYEGSITVALS 2749
Query: 1182 SGLFEKPKATELIEFSTIKVTVPSDITTA--FSSVDRLHTTSAFKPSSAITKKPPLIDRE 1239
T+P+ T + FS T+A SSA ++ ++
Sbjct: 2750 --------------------TLPAGTTGSLVFSQSSENSETTALVDSSAGLERASVMPLT 2789
Query: 1240 PGEETTSDMVIIGESTSHVPPT-TLEDIVAKETETDIDR-EYFTTSSPPATQPTRPPTVE 1297
G + + I ++H T T + ++ TT+ ATQ T P +
Sbjct: 2790 TGSQGMASSGGIRSGSTHSTGTKTFSSLPLTMNPGEVTAMSEITTNRLTATQSTAPKGIP 2849
Query: 1298 DKEAFGPQALSTPQPPASTKFHPDINVYIIE-----VRENKTGRMSDLSVIGHPIDSESK 1352
K L TP +S+ ++ + T S++ +D++S
Sbjct: 2850 VKPTSAESGLLTPVSASSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVP----SLDTKSA 2905
Query: 1353 EDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYIN 1412
+ + + D A S + E+ A +T+T ++ +
Sbjct: 2906 SLPTPGQSLNTIPDSDASTA-------------SSSLSKSPEKNPRARMMTSTKAISASS 2952
Query: 1413 GKHLVTTVPKDPEAAEARRGQFESVAPSQNFSD---SSESDTHPFVIAKTELSTAVQPNE 1469
+ T + A+ + G E P+ D +SES ++P P++
Sbjct: 2953 FQSTGFTETPEGSASPSMAGH-EPRVPTSGTGDPRYASESMSYP------------DPSK 2999
Query: 1470 STETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEV 1529
++ S + K T FS G + SG++ TE++T
Sbjct: 3000 ASSAMTSTSLASKLTTL------FSTG-----------QAARSGSSSSPISLSTEKETSF 3042
Query: 1530 GHQAHEHTEPVSLFPEES-SGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVP 1588
+ SLF S + + I Q A + T E+ +T + TI
Sbjct: 3043 LSPTASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTSTLNMSQEEPPELTSSQTIAE 3102
Query: 1589 SSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEED 1648
+ +E + +T + P LL R+ + +SSI + + E
Sbjct: 3103 EEGT--TAETQTLTFTPSETPTSLLPVSSPTEPTARRKSSPETWASSISVPAKTSLVETT 3160
Query: 1649 EDTMFT---MVTDLSQRNTTDTLITLDTSRI---ITESFFEVPATTIYPVSEQPSAKVVP 1702
+ T+ T M + +Q N+T +T + E+ T S++PS +
Sbjct: 3161 DGTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAGTSPGSPEMSTTLKIMSSKEPS---IS 3217
Query: 1703 TKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELESPNVA 1762
+ S S W + T + E T ST ST S LP SP +
Sbjct: 3218 PEIRSTVRNSPWKTPETTVPMETTVEPVT--LQSTALGSGSTSISH---LPTGTTSPTKS 3272
Query: 1763 TSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTETN--TLENLGAQTTEHSSIHQPGVQEG 1820
+ + + +P ++ + TP T + T+ ++ ++ SI G Q
Sbjct: 3273 PTENMLATERVSLSPSPPEAWTNLYSGTPGGTRQSLATMSSVSLESPTARSITGTGQQSS 3332
Query: 1821 LTTLPRSPASVF-MEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEVAGTLSPHVETTFS 1879
+ ++ F M GS ++S+ S +E + + V+ T +
Sbjct: 3333 PELVSKTTGMEFSMWHGSTGGTTGDTHVSLSTSSNILEDPVTSPNSVSSLTDKSKHKTET 3392
Query: 1880 TEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPLEEDFSGDFR 1939
T + STV++ + QTSR V ++ + G D +
Sbjct: 3393 WVSTTAIPSTVLNNKIMAAEQQTSRS-VDEAYSSTSSWSDQTSGSDITLGASPDVTNTLY 3451
Query: 1940 EYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVPTSVHISHISDSEGPSSTMVSTSAF 1999
ST A+ +++ SGD + T+PS TS S S S G + + SA
Sbjct: 3452 ITST-----AQTTSLVSLPSGDQGI-TSLTNPSGGKTSSASSVTSPSIGLETLRANVSAV 3505
Query: 2000 PWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQKFSGTASSIIDEGLGEVGTVNEIDRRST 2059
+ A +G T S + V +L G +++I G + ST
Sbjct: 3506 K----SDIAPTAGHLSQTSSPAEVSILDVTTAPTPGISTTITTMGTNSI---------ST 3552
Query: 2060 ILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQTIEPAKLWSRQEVNPVRQEIESETTSEEQ 2119
P EV + ++ T ST P T WS + T +
Sbjct: 3553 TTPNPEV--GMSTMDSTPATERRTTSTEHPST------WSSTAAS-------DSWTVTDM 3597
Query: 2120 IQEEKSFESPQNSPATEQTIFDSQTFTETELKTTDYSVLTTKKT-----YSDDKEMK-EE 2173
K SP T F + + TE + +T + +T T SD +K E
Sbjct: 3598 TSNLKVARSPGTISTMHTTSFLASS-TELDSMSTPHGRITVIGTSLVTPSSDASAVKTET 3656
Query: 2174 DTSLVNMSTPDPDAN-GLESYTTLPEATEKSHFFLATALVTESIPAEHVVTDSPIKKEES 2232
TS +S D A+ + +++ + + L+T+ S AE V S
Sbjct: 3657 STSERTLSPSDTTASTPISTFSRVQRMSISVPDILSTSWTPSSTEAEDVPVSMVSTDHAS 3716
Query: 2233 TKHFPKGMRPTIQESDTELL--FSGLGSGEEVLPTLPTESVNFTEVEQINNTLYPHTSQV 2290
TK P T L +G T + + + + P TSQ+
Sbjct: 3717 TKTDPNTPLSTFLFDSLSTLDWDTGRSLSSATATTSAPQGATTPQELTLETMISPATSQL 3776
Query: 2291 ESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVTSTTLIEILSDTGAEGPTVAPLP 2350
S I +A+ G S+ D TST L PT
Sbjct: 3777 -PFSIGHITSAVTPAAMARSSGVTFSRPDPTSKKAEQTSTQL-----------PT----- 3819
Query: 2351 FSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSNKNSSTAEINETTTSSTDFLARAYGFEM 2410
T HP Q R A P T D +T + T +T+ A + +
Sbjct: 3820 --TTSAHP-GQVPRSAATTLDVIPHTAKTPD-----ATFQRQGQTALTTEARATSDSWNE 3871
Query: 2411 AKEFVTSAPKPSDLYYEPSGEGSGEVDIVDSFHTSATTQATRQESSTT------------ 2458
++ SAP +++ S + EV S + T ES TT
Sbjct: 3872 KEKSTPSAPWITEMMNSVSEDTIKEVTSSSSVLRTLNTLDINLESGTTSSPSWKSSPYER 3931
Query: 2459 -FVSDGSLEKHPEVPSAKAVTADGFPTVS-----VMLPLHSEQNK-SSPDPTSTLSNTVS 2511
S+ + +K PS V G+ T S +P HS +K +SP T++
Sbjct: 3932 IAPSESTTDKEAIHPSTNTVETTGWVTSSEHASHSTIPAHSASSKLTSPVVTTSTREQAI 3991
Query: 2512 YERSTDGSFQDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDLILTITESTILEILPELT 2571
ST + +ST R +P + I+L + + T T + P T
Sbjct: 3992 VSMST--------TTWPESTRA--RTEPNSFLTIELRDVSPYMDTSSTTQTSIISSPGST 4041
Query: 2572 S-DKNTIIDIDHTKPVYEDILGMQTDIDTEVPSEP------HDSNDESNDDSTQVQEIYE 2624
+ K +I +K + L Q+ ++ PSE + ES +Q
Sbjct: 4042 AITKGPRTEITSSKRISSSFLA-QSMRSSDSPSEAITRLSNFPAMTESGGMILAMQTSPP 4100
Query: 2625 AAVNLSL----TEETFEGSADVLASYTQATHDESMTY-----EDRSQLDHMGFHFTTG-- 2673
A +LS T T + LA+ + T+ E T ED SQ T+
Sbjct: 4101 GATSLSAPTLDTSATASWTGTPLATTQRFTYSEKTTLFSKGPEDTSQPSPPSVEETSSSS 4160
Query: 2674 --IPAPSTETELDVLLPTATSLPIPRKSATVIPEIEGIKAEAKALDDMFESSTLSDGQAI 2731
+P +T + ++LL + P ++ P +E L + S +S
Sbjct: 4161 SLVPIHATTSPSNILLTSQGHSP-----SSTPPVTSVFLSETSGLGKTTDMSRISLEPGT 4215
Query: 2732 ADQSEIIPTLGQFERTQEEYEDKK---HAGPS--FQPEFSSGAEEALVDHT----PYLSI 2782
+ + T G+ T E D K H+ + E +S + HT +
Sbjct: 4216 SLPPNLSSTAGEALSTYEASRDTKAIHHSADTAVTNMEATSSEYSPIPGHTKPSKATSPL 4275
Query: 2783 ATTHLMDQSVTEVPDVMEGSNPPYYTDTTLAV-------STFAKLSSQTPSSP-LTIYSG 2834
T+H+M +T V GS+ +T +V ST SS T +S +T S
Sbjct: 4276 VTSHIMG-DITSSTSVF-GSSETTEIETVSSVNQGLQERSTSQVASSATETSTVITHVSS 4333
Query: 2835 SEASGHTEIPQPSALPGIDVGSSVMSPQDSFKEIHVNIEATFKPSSEEYLHITEPPSLSP 2894
+A+ H Q + G+S+ SP + + + PS+ L +TE ++
Sbjct: 4334 GDATTHVTKTQAT----FSSGTSISSPHQFITSTNTFTDVSTNPSTS--LIMTESSGVTI 4387
Query: 2895 DTKLEPS----------EDDGKPELLEEMEASPTELIAVEGTEILQDFQNKTDGQVS--- 2941
T+ P+ + P L E A + + E T ++ +K VS
Sbjct: 4388 TTQTGPTGAATQGPYLLDTSTMPYLTETPLAVTPDFMQSEKTTLI----SKGPKDVSWTS 4443
Query: 2942 --GEAIKMFPTIKTPEAGTVITTADEIELEGATQWPHSTS-ASATYGVEAGVVPWLSPQT 2998
A +P+ TP T I A Q H++S SAT + +G+V
Sbjct: 4444 PPSVAETSYPSSLTPFLVTTIPPA-----TSTLQGQHTSSPVSATSVLTSGLVKTTDMLN 4498
Query: 2999 SERPTLSSSPE--INPETQAALIRGQDSTIAASEQQVAARILDSNDQATVN------PVE 3050
+ +++SP+ NP + + I + + + ++ + PV
Sbjct: 4499 TSMEPVTNSPQNLNNPSNEILATLAATTDIETIHPSINKAVTNMGTASSAHVLHSTLPVS 4558
Query: 3051 FNTEVATPPFSLLETSNETDFLIGINEESVEGTAI 3085
AT P ++ S+ D L I+ E T I
Sbjct: 4559 SEPSTATSP--MVPASSMGDALASISIPGSETTDI 4591
Score = 65.9 bits (159), Expect = 7e-10
Identities = 549/2798 (19%), Positives = 948/2798 (33%), Gaps = 462/2798 (16%)
Query: 579 VITVSKTSEDTIHTHLEDLESVSASTTVSP--LIMPDNNG-----SSMDDWEERQTSGRI 631
V+T+S ++E T ++ ++++ ++ SP L +P +G SS TSG
Sbjct: 806 VLTLSTSAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEE 865
Query: 632 TEEFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRERTET-L 690
TEE ++ P SQ T + + + + T ++P++ T T + + + L
Sbjct: 866 TEE------TSNPSVSQPETSVSRVRTT---LASTSVPTPVFPTMDTWPTRSAQFSSSHL 916
Query: 691 IPEMRTDTYTDEIQE---------EITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSV 741
+ E+R + T +T + M +T + F+ S + P E+S
Sbjct: 917 VSELRATSSTSVTNSTGSALPKISHLTGTATMSQTNRDTFNDSAAPQSTTWP----ETSP 972
Query: 742 EMTKSFDFPTLITKLSAEPTEVRDMEEDFTATPGTTKYD-----ENITTVLLAH-----G 791
T SA M FT+ P T+ + E TT+L G
Sbjct: 973 RFKTGLPSATTTVSTSATSLSATVMVSKFTS-PATSSMEATSIREPSTTILTTETTNGPG 1031
Query: 792 TLSVEAA----------------------TVSKWSWDEDNTTSKPLESTEPSASSKLPPA 829
+++V + T + D T +K S S S + A
Sbjct: 1032 SMAVASTNIPIGKGYITEGRLDTSHLPIGTTASSETSMDFTMAKESVSMSVSPSQSMDAA 1091
Query: 830 LLTTVGMNGKDKDIPSFTED----GADEFTLIPDSTQKQLEEVTDEDIAAHGKFTIRFQP 885
+T G + D +F++D + E T+ D T L T + A H P
Sbjct: 1092 GSSTPGRTSQFVD--TFSDDVYHLTSREITIPRDGTSSAL---TPQMTATH-------PP 1139
Query: 886 TTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSK--------PV 937
+ G A + L ++ P T ++T + ++ V+ S+
Sbjct: 1140 SPDPGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTT 1199
Query: 938 STVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHT-IP-LSVIPKTDWGVLVPSVPSEDE 995
S P TS G + + T P T +++S +P LS P++ PS+
Sbjct: 1200 SLTPSNIPTSGAIGKSTLVPLDTPSPATSLEASEGGLPTLSTYPES---TNTPSIHLGAH 1256
Query: 996 VLGE-PSQDILVIDQTRLEATISPETMRT--TKITEGTTQEEFPWKEQTAEKPVPALSST 1052
E PS L + + +P T + T I T + + + E P ++T
Sbjct: 1257 ASSESPSTIKLTMASVVKPGSYTPLTFPSIETHIHVSTARMAYS-SGSSPEMTAPGETNT 1315
Query: 1053 A--WTPKEAVTPLDEQEGDGSAYTVSED-ELLTGSERVPVLET-TPVG-----KIDHSVS 1103
W P +T D ++ + + L +E P E+ TP KI S +
Sbjct: 1316 GSTWDPTTYITTTDPKDTSSAQVSTPHSVRTLRTTENHPKTESATPAAYSGSPKISSSPN 1375
Query: 1104 YPPGAV--------TEHKVKTDEVVTLTPRIGPKVSLSPGPEQKY----ETEGSSTTGFT 1151
A TEH + G + +PGP T GSST T
Sbjct: 1376 LTSPATKAWTITDTTEHSTQLHYTKLAEKSSGFETQSAPGPVSVVIPTSPTIGSSTLELT 1435
Query: 1152 SSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDITTAF 1211
S + P + E+TT I L + TE + + + ++ PS + F
Sbjct: 1436 SDV-PGEPLVLAPSEQTT--------ITLPMATWLSTSLTEEMASTDLDISSPSSPMSTF 1486
Query: 1212 SSVDRLHT-----------TSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPP 1260
+ + T TSA + + + T L R G T D+ +T + P
Sbjct: 1487 AIFPPMSTPSHELSKSEADTSAIRNTDSTTLDQHLGIRSLGR--TGDL-----TTVPITP 1539
Query: 1261 TTLEDIVAKETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHP 1320
T E T T SP T T+ +++D+ + A P T+ +P
Sbjct: 1540 LTTTWTSVIEHSTQAQDTLSATMSP--THVTQ--SLKDQTSIPASA----SPSHLTEVYP 1591
Query: 1321 DINVYIIEVRENKTGRMSDLSVIGHPIDS--ESKEDEPCSEETDPVHDLMAEILPEFPDI 1378
++ E T + I++ + + P + T L I
Sbjct: 1592 ELGTQGRSSSEATTFWKPSTDTLSREIETGPTNIQSTPPMDNTTTGSSSSGVTL----GI 1647
Query: 1379 IEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVTTVP-KDPEAAEARRGQFESV 1437
+ + S E T T S+ G LVT+ P + + R S
Sbjct: 1648 AHLPIGTSSPAETSTNMALERRSSTATVSMAGTMGL-LVTSAPGRSISQSLGRVSSVLSE 1706
Query: 1438 APSQNFSDSSESDTHPF-VIAKTELSTAVQPN--ESTETTESLEVTWKPETYPETSEHFS 1494
+ ++ +DSS+ + T LS++++P+ E ++ + S+ +T P T P+ F
Sbjct: 1707 STTEGVTDSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMSTSIPLTSSPTT-PDVE--FI 1763
Query: 1495 GGEP--DVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQAH------------------ 1534
GG T + +A+ + S T T +G +
Sbjct: 1764 GGSTFWTKEVTTVMTSDISKSSARTESSSATLMSTALGSTENTGKEKLRTASMDLPSPTP 1823
Query: 1535 --EHTEPVSL-----------------FPEESSGEIAIDQESQKIAFARATEVTFGEEVE 1575
E T +SL S+G +A D+ S RA+ + G +
Sbjct: 1824 SMEVTPWISLTLSNAPNTTDSLDLSHGVHTSSAGTLATDR-SLNTGVTRASRLENGSDTS 1882
Query: 1576 KSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATP--RQVVELSGS 1633
+ T ++ Y + E + I +P P+ E+ + +TP R +
Sbjct: 1883 SKSLSMGNST---HTSMTYTEKSEVSSSI-HPRPETSAPGAETTLTSTPGNRAISLTLPF 1938
Query: 1634 SSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIYPVS 1693
SSIP+ EE T T D++ T + IT T I+ S + +T
Sbjct: 1939 SSIPV-------EEVISTGITSGPDINSAPMTHSPITPPT--IVWTSTGTIEQST----- 1984
Query: 1694 EQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILP 1753
QP V K +T ++ +++S V E ++G+ ST YSS L
Sbjct: 1985 -QPLHAVSSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGS-STSSPYSSASLES---LD 2039
Query: 1754 FELESPNVATSSDSGTRKSFMSLTTPTQSEREMTDS--TPVFTETNTLENLGAQTTEHSS 1811
+ N TS S + T P+ S E S + V ++T + +S
Sbjct: 2040 STISRRNAITSWLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTS 2099
Query: 1812 IHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEY--AIQAEKEVAG- 1868
+ E T P++ A+ + + ET +S S V AI + +V+G
Sbjct: 2100 AAKQRNPETETHGPQNTAASTLNTDASSVTGLSETPVGASISSEVPLPMAITSRSDVSGL 2159
Query: 1869 ----TLSPHVETTFSTEPTGLVLSTVMDRVVAENI-----------------------TQ 1901
T +P + T S G L+ + +E++ T+
Sbjct: 2160 TSESTANPSLGTASSA---GTKLTRTISLPTSESLVSFRMNKDPWTVSIPLGSHPTTNTE 2216
Query: 1902 TSREI----------VISERLGEPNYGAE---IRGFSTGFPLE--------EDFSGDFRE 1940
TS + V S+ + P+ GAE FS E E + FR
Sbjct: 2217 TSIPVNSAGPPGLSTVASDVIDTPSDGAESIPTVSFSPSPDTEVTTISHFPEKTTHSFRT 2276
Query: 1941 YSTVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVPTSVHISH---ISDSEGPSSTMVSTS 1997
S+++H + T + GD T P+ S+ + I+ + +S +V T+
Sbjct: 2277 ISSLTHELTSRVTPI---PGDWMSSAMSTKPTGASPSITLGERRTITSAAPTTSPIVLTA 2333
Query: 1998 AFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQKFSGTASSIIDEGLGEVGTVNEIDRR 2057
+F TS+ E V S + + + S ++S +I+ + + ++ +
Sbjct: 2334 SFTE---TSTVSLDNETTVKTSDILDARKTNELPSDSSSSSDLINTSIAS--STMDVTKT 2388
Query: 2058 STILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQTIEPAKLWSRQEVNPVRQEIESETTSE 2117
++I PT+ +SG +++ P L+S E+ T +
Sbjct: 2389 ASISPTS---------------ISGMTASSSPS------LFSSDRPQVPTSTTETNTATS 2427
Query: 2118 EQIQEEK-SFESPQNSPATEQTI----FDSQTFTETELKTTDYSVLTTKKTYSDDKEMKE 2172
+ S + N T T+ T + L V T S D E
Sbjct: 2428 PSVSSNTYSLDGGSNVGGTPSTLPPFTITHPVETSSALLAWSRPVRTFSTMVSTDTASGE 2487
Query: 2173 EDTSL--VNMSTPDPDA-NGLESYTTLP-------EATEKSHFFLATALVTESIPAEH-- 2220
TS V S P P + S T LP ++H LA+ + + H
Sbjct: 2488 NPTSSNSVVTSVPAPGTWTSVGSTTDLPAMGFLKTSPAGEAHSLLASTIEPATAFTPHLS 2547
Query: 2221 --VVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGEEVLPTLPTESVNF-TEVE 2277
VVT S E S + S+++ + S + PT PT N+ T
Sbjct: 2548 AAVVTGSSATSEASL----------LTTSESKAIHSSPQT-----PTTPTSGANWETSAT 2592
Query: 2278 QINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVTSTTLIEILS 2337
+ + TS TS + D V+ + F +G+++ + +L
Sbjct: 2593 PESLLVVTETSDTTLTSKILVTDTILFSTVS-------TPPSKFPSTGTLSGASFPTLLP 2645
Query: 2338 DTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSNKNSSTAEINETTTS 2397
DT A T S V A + + P+T N + +
Sbjct: 2646 DTPAIPLTATEPTSSLATSFDSTPLVTIASDSLGTVPETTLTMSETSNGDALVLKTVSNP 2705
Query: 2398 STDFLARAYGFEMAKEFVTSAPKPSDLYYEPSGEGSGEVDIVDSFHTSATTQA-----TR 2452
S+ PS + + G + + S + TT + +
Sbjct: 2706 DRSIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSITVALSTLPAGTTGSLVFSQSS 2765
Query: 2453 QESSTTFVSDGS--LEKHPEVP----SAKAVTADGFPTVSVMLPLHSEQNKSSPDPTSTL 2506
+ S TT + D S LE+ +P S ++ G + S HS K+ T+
Sbjct: 2766 ENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSGST----HSTGTKTFSSLPLTM 2821
Query: 2507 SN---TVSYERSTDGSFQDRFREFEDSTLKPNRKKPTENIIIDLDKEDKDLILTITESTI 2563
+ T E +T+ + + +KP + + ++T +
Sbjct: 2822 NPGEVTAMSEITTNRLTATQSTAPKGIPVKPTSAESGLLTPVSASSSPSKAFASLTTAPP 2881
Query: 2564 LEILPE--LTSDKNTIIDIDHTK---PVYEDILGMQTDIDTEVPSEPHDSNDESNDDS-- 2616
+P+ LT + + + +D P L D D S + E N +
Sbjct: 2882 TWGIPQSTLTFEFSEVPSLDTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEKNPRARM 2941
Query: 2617 -TQVQEIYEAAVNLSLTEETFEGSADVLASYTQATHDESMTYEDRSQLDHMGFHFTTGIP 2675
T + I ++ + ET EGSA + + S T + R + M + +
Sbjct: 2942 MTSTKAISASSFQSTGFTETPEGSASPSMAGHEPRVPTSGTGDPRYASESMSYPDPSKAS 3001
Query: 2676 APSTETELDVLLPTATSLPIPRKSATVIPEIEGIKAEAKALDDMFESSTLSDGQAIADQS 2735
+ T T L L T S +S G + +L E+S LS
Sbjct: 3002 SAMTSTSLASKLTTLFSTGQAARS--------GSSSSPISLSTEKETSFLS--------- 3044
Query: 2736 EIIPTLGQFERTQEEYEDKKHAGPSF--QPEFSSGAEEALVDHTPYLSIATTHLMDQSVT 2793
PT +T GPS QP + T L+++ T ++ S
Sbjct: 3045 ---PTASTSRKTS------LFLGPSMARQPNILVHLQ------TSALTLSPTSTLNMSQE 3089
Query: 2794 EVPDVMEGSNPPYYTDTTLAVSTFAKLSSQTPSSPLTIYSGSEASGHTEIPQPSALPGID 2853
E P++ TT T S+TP+S L + S +E + + + I
Sbjct: 3090 EPPELTSSQTIAEEEGTTAETQTLTFTPSETPTSLLPVSSPTEPTARRKSSPETWASSIS 3149
Query: 2854 V--GSSVMSPQDSFKEIHVNIEATFKPSSEEYLHITEPPSLSPDTKLEPS-EDDGKPELL 2910
V +S++ D + T K SS+ + P+ + +T P+ G PE+
Sbjct: 3150 VPAKTSLVETTDG------TLVTTIKMSSQAAQGNSTWPAPAEETGSSPAGTSPGSPEMS 3203
Query: 2911 EEMEASPTELIAVEGTEILQDFQNKTDGQVSGEAIKMFPTIKTPEAGTVI-TTADEIELE 2969
++ ++ ++ EI +N KTPE + TT + + L+
Sbjct: 3204 TTLKIMSSKEPSI-SPEIRSTVRNS--------------PWKTPETTVPMETTVEPVTLQ 3248
Query: 2970 GATQWPHSTSAS--ATYGVEAGVVPWLSPQTSERPTLSSSPEINPETQAALIRGQDSTIA 3027
STS S T P + +ER +LS SP PE L G T
Sbjct: 3249 STALGSGSTSISHLPTGTTSPTKSPTENMLATERVSLSPSP---PEAWTNLYSG---TPG 3302
Query: 3028 ASEQQVAARILDSNDQATVNPVEFNTEVATPPFSLLETSNETDFLIGINEESVEGTAIYL 3087
+ Q +A S + T + + ++P T E G + T + L
Sbjct: 3303 GTRQSLATMSSVSLESPTARSITGTGQQSSPELVSKTTGMEFSMWHGSTGGTTGDTHVSL 3362
Query: 3088 PGPDRCKMNP--------CLNGGTCYPTETSYVCTCVP 3117
+P L + + TET T +P
Sbjct: 3363 STSSNILEDPVTSPNSVSSLTDKSKHKTETWVSTTAIP 3400
Score = 49.3 bits (116), Expect = 6e-05
Identities = 201/1003 (20%), Positives = 345/1003 (34%), Gaps = 111/1003 (11%)
Query: 2082 GTVSTNFPQTIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFD 2141
G +S+ P++ S Q +P + T S S S +SP T +T
Sbjct: 80 GVMSSALPESTSRGMTHSEQRTSPSLSPQVNGTPSRNY--PATSMVSGLSSPRT-RTSST 136
Query: 2142 SQTFTETELKTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDP-DANGLESYTTLPEAT 2200
FT+ E T +V TT ++ + E ++ ST P D + T P T
Sbjct: 137 EGNFTK-EASTYTLTVETTSGPVTEKYTVPTETSTTEGDSTETPWDTRYIPVKITSPMKT 195
Query: 2201 EKSHFFLATALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLGSGE 2260
PAE VTDS H P P+ + L
Sbjct: 196 FADSTASKENAPVSMTPAETTVTDS---------HTPGRTNPSFGTLYSSFL-------- 238
Query: 2261 EVLPTLPTESVNFTEVEQINNTL-YPHTS-QVESTSSDKIEDFNRMENVAKEVGPLVSQT 2318
++ P S T +E I +T YP +S + S +I + + A + +S+T
Sbjct: 239 DLSPKGTPNSRGETSLELILSTTGYPFSSPEPGSAGHSRISTSAPLSSSASVLDNKISET 298
Query: 2319 DIFEGSGSVTSTTLIEILSDTGAEGPTVAPLPFSTDIGHPQNQTVRWAEEIQT-SRPQTI 2377
IF G S+TS + + P A +PFS + + + R I + P
Sbjct: 299 SIFSGQ-SLTSPLSPGVPEARASTMPNSA-IPFSMTLSNAETSAERVRSTISSLGTPSIS 356
Query: 2378 TEQDSNKNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPSDLYYEPSGEGSGEVD 2437
T+Q + + ET + +A+ E T + S + +
Sbjct: 357 TKQTAETILTFHAFAETMDIPSTHIAKTLASEWLGSPGTLGGTSTSALTTTSPSTTLVSE 416
Query: 2438 IVDSFHTSA--TTQATRQESSTTFVSDGSLEKHPEVPSAKAVTADGFPTVSVMLPLHSEQ 2495
++ H+++ T+ T S T + E+ +A V GF T+ + S+
Sbjct: 417 ETNTHHSTSGKETEGTLNTSMTPLETSAPGEESEM--TATLVPTLGFTTLDSKIRSPSQV 474
Query: 2496 NKSSPD----PTSTLSNTVSYERSTDGSFQDRFREFEDSTLKPNR----------KKPTE 2541
+ S P T + S S + GS D R ST K + +P
Sbjct: 475 SSSHPTRELRTTGSTSGRQSSSTAAHGS-SDILRATTSSTSKASSWTSESTAQQFSEPQH 533
Query: 2542 NIIIDLD---KEDKDLILTITESTILEILPELTSDKNTIIDIDHTKPVYEDILGMQTDID 2598
++ K ++ T + I +P + S T+ TK ++ + +T D
Sbjct: 534 TQWVETSPSMKTERPPASTSVAAPITTSVPSVVSGFTTL-KTSSTKGIWLE----ETSAD 588
Query: 2599 TEVPSEPHDSNDESNDDSTQVQEIYEAAVNLSLTEETFEGSADVLASYTQATHDESMTYE 2658
T + ES T Q ++++ T GS T+AT S T
Sbjct: 589 TLI--------GESTAGPTTHQFAVPTGISMTGGSST-RGSQGTTHLLTRATAS-SETSA 638
Query: 2659 DRSQLDHMGFHFTTGIP---APSTETELDVLLPTATSLPIPRKSATVIPEIEGIKAEAKA 2715
D + T G+P +P+ P + P ++VIPE +++ A
Sbjct: 639 DLTLA-------TNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETSSLQSSAFR 691
Query: 2716 LDDMFESSTLS----------DGQAIADQSEIIPTLGQFERTQEEYEDKKHAGPSFQ--- 2762
+ L+ D S IP L + EDK A +F
Sbjct: 692 EGTSLGLTPLNTRHPFSSPEPDSAGHTKISTSIPLLS----SASVLEDKVSATSTFSHHK 747
Query: 2763 --PEFSSGAEEALVDHTPYLSIATTHLMDQSVTEVPDVMEGSNP-----PYYTDTTLAVS 2815
++G E P ++ ++ + + T V ++P P +T +V
Sbjct: 748 ATSSITTGTPEISTKTKPSSAVLSSMTLSNAATSPERVRNATSPLTHPSPSGEETAGSVL 807
Query: 2816 TFAKLSSQTPSSPLTIYSGSEASGHTEIPQPSALPGIDVGSSVMSPQDSFKEIHVNIEAT 2875
T + S++T SP +G+ S +E P +LP + + S + + E T
Sbjct: 808 TLST-SAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEET 866
Query: 2876 FKPSSEEYLHITEPPSLSPDTKLEPSEDDGKPELLEEMEASPTELIAVEGTEILQDFQNK 2935
+ S+ +++P + + + + M+ PT + ++ + +
Sbjct: 867 EETSNPS---VSQPETSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHLVSELRAT 923
Query: 2936 TDGQVSGEAIKMFPTIK--TPEAGTVITTADEIELEGA---TQWPHSTSASATYGVEAGV 2990
+ V+ P I T A T D A T WP TS G+ +
Sbjct: 924 SSTSVTNSTGSALPKISHLTGTATMSQTNRDTFNDSAAPQSTTWP-ETSPRFKTGLPSAT 982
Query: 2991 VPWLSPQTSERPTLSSSPEINPET---QAALIRGQDSTIAASE 3030
+ TS T+ S +P T +A IR +TI +E
Sbjct: 983 TTVSTSATSLSATVMVSKFTSPATSSMEATSIREPSTTILTTE 1025
>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
sapiens]
Length = 1521
Score = 118 bits (296), Expect = 9e-26
Identities = 314/1476 (21%), Positives = 510/1476 (34%), Gaps = 175/1476 (11%)
Query: 1403 TTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELS 1462
TTT S G T + K E A E+ PS S ++ I T S
Sbjct: 15 TTTAST---TGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTT--S 69
Query: 1463 TAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGA-ES 1521
TA N + + S T ET+ +G E S + S
Sbjct: 70 TAGSENTTVSSAGS-GTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS 128
Query: 1522 VTERDTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTSVT 1581
T +T V A T VS E++ D E+ + T G E+ +
Sbjct: 129 TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAAS-------TTGSEMT-TVFTA 180
Query: 1582 YTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPITEG 1641
+ TI PS+A SE V+ G+ + E+ +T E + +S++
Sbjct: 181 GSETITPSTAG---SETTTVSTAGSETTTVSTTGSETTTASTAHS--ETTAASTMGSETT 235
Query: 1642 SGEAEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITE-SFFEVPATTIYPVSEQPSAKV 1700
E T+ T ++ + +T D+ +T+ TE S +TT + + +
Sbjct: 236 KVSTAGSETTVSTAGSETTAASTEDS----ETNTAFTEDSKTTTASTTGFETTAASTTGS 291
Query: 1701 VPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELESPN 1760
PT ++ T SE ++T+ + K ++ + F S T R+ + E+
Sbjct: 292 EPT--MASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTV----GSETTT 345
Query: 1761 VATSSDSGTRKSFMSLTTPTQSEREMTDSTPVFTETNTLENLGAQTTEHSSIHQPGVQEG 1820
V+T+ T S M T T DST +ET T G++TT S+ EG
Sbjct: 346 VSTTGSETTTASIMGSETST-------DST-TGSETTTASTEGSETTTAST-------EG 390
Query: 1821 LTTLPRSPASVFMEQGSGEAAADPETTTVS-SFSLNVEYAIQAEKEVAGTLSPHVETTFS 1879
S A+ GS ETTTVS + S + + A + + TT S
Sbjct: 391 ------SEATTVSTTGS-------ETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAS 437
Query: 1880 TEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPLEEDFSGDFR 1939
TE + + +++ D T+ S ++ G+E + T S
Sbjct: 438 TEGSEITIASTSDSETTTASTEGSETTTVTTA------GSETKTAYTTGSETTTASNTGL 491
Query: 1940 EYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVPTSVHISHISDSEGPSSTMVSTSAF 1999
E +TV + T EGS A T + +TV T + + G +T VST+
Sbjct: 492 ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGL 551
Query: 2000 PWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQKFSGTASSIIDEGLGEVGTVNEIDRRST 2059
E T+S EGS ++ TVS++ + + TA+S E TV+ D +T
Sbjct: 552 --ETTTTSTEGS--EMTTVSTTGAETTTDSTEGSGTTAASTAGS---ETTTVSTADSENT 604
Query: 2060 ILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQTIEPAKLWSRQEVNPVRQEIESETTSEEQ 2119
TA+ E T A E + T S+ E + +SETT
Sbjct: 605 TASTADSETTSASTTGSETTTASTTSS------ETTTASTEGSETTTVSTTDSETTMVST 658
Query: 2120 IQEEKSFESPQNSPATEQTIFDSQTFTETELK-TTDYSVLTTKKTYSDDKEMKEEDTSLV 2178
E++ S + S T + S+T TE TT S+ ++ T + TS
Sbjct: 659 TGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTE 718
Query: 2179 NMSTPDPDANGLESYTTLPEATEKSHFFLATALVTESIPAEHVVTDSPIKKEESTKHFPK 2238
G E+ T E +E + T S + S E +T
Sbjct: 719 GSEITTASITGSETTTASTEGSETT---------TASTEGSETTSASTTGSETTTA---- 765
Query: 2239 GMRPTIQESDTELLFSGLGSGEEVLPTLPTESVNFTEVEQINNTLYPHTSQVESTSSDKI 2298
+ S+T + S +GS + T+ +E+ + T++ S+ S+
Sbjct: 766 ----STTSSETTMA-SIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTAS 820
Query: 2299 EDFNRMENVAKEVGPLVSQTDIFEGSGSVTSTTLIEILSDTGAEGPTVAPLPFSTDIGHP 2358
E V S+T +GS T+TT S G+E T + T
Sbjct: 821 E--------TTTVSTAGSETIPASTAGSETTTTT----STEGSETTTASTEGSETTTAST 868
Query: 2359 QNQTVRWAEEIQTSRPQTITEQDSNKNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSA 2418
++ A I + TE +ST E +ETTT+ST
Sbjct: 869 ESSETTTATTIGSETTTASTEGSETTTTST-EGSETTTAST------------------- 908
Query: 2419 PKPSDLYYEPSGEGSGEVDIVDSFHTSATTQATRQESSTTFVSDGSLEKHPEVPSAKAVT 2478
EGS E+ V + + TT +T +TT ++GS ++ +T
Sbjct: 909 ------------EGS-EITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETIT 955
Query: 2479 --ADGFPTVSVMLPLHSEQNKSSPDPTSTLSNTVSYERSTDGSFQDRFREFEDSTLKPNR 2536
A+G T +V + SE +S + T + + + +T S + ST
Sbjct: 956 VSAEGSETTTV-TTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETT 1014
Query: 2537 KKPTENIIIDLDKEDKDLILTITESTILEILPELTSDKNTIIDIDHTKPVYEDILGMQT- 2595
T + + T+T + T + T + ++ G +T
Sbjct: 1015 TVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETT 1074
Query: 2596 -----DIDTEVPSEPHDSNDESNDDSTQVQEIYEAAVNLSLTEETFEGSADVLASYTQAT 2650
D++T S ++ ++ +Y T + EGS S T +
Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVY--ITGSKTTTASTEGSEATTVSTTSSE 1132
Query: 2651 HDESMTYEDRSQLDHMGFHFTTGIPAPSTETELDVLLPTATSLPIPRKSATVIPEIEGIK 2710
+ T G TT S T + + AT+ AT EG +
Sbjct: 1133 TTTAST---------TGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATT-TSTEGSE 1182
Query: 2711 AEAKALDDMFESSTLSDGQAIADQSEIIPTLGQFERTQEEYEDKKHAGPSFQPEFSSGAE 2770
+ ++ + G S T E AG F G+E
Sbjct: 1183 TTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSE 1242
Query: 2771 EALVDHTPYLSIATTHLMDQSVTEVPDVMEGSNPPYYTDTTLAVSTFAKLSSQTPS-SPL 2829
+ T L T L T V G+ TT++ +TF + S P+
Sbjct: 1243 TTIAS-TASLEPTATSLTGSETTTVSITASGATA---ASTTVSSTTFVLTKATDVSIQPI 1298
Query: 2830 --TIYSGSEASGHTEIPQPSAL---PGIDVGSSVMS 2860
T SG+ +G T + S++ PG+D +S S
Sbjct: 1299 TNTPMSGTRTTG-TRLTASSSVTMAPGMDFTASAAS 1333
Score = 114 bits (284), Expect = 2e-24
Identities = 274/1275 (21%), Positives = 437/1275 (34%), Gaps = 132/1275 (10%)
Query: 955 VSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEA 1014
VS S ++ TT S +S G S+ + + + + T E
Sbjct: 58 VSISGSEITTTSTAGSENTTVS---SAGSGTTTASMAGSETTVSTAGSETTTVSITGTET 114
Query: 1015 TI----SPETMRTTKITEGTTQEEFPWKEQTAEKPVPALSSTAWTPKEAVTPLDEQEGDG 1070
T+ ET + + TT E T V + ++TA+T T +
Sbjct: 115 TMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM 174
Query: 1071 SAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKV 1130
+ + E +T S T + + G+ T T +G +
Sbjct: 175 TTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSET 234
Query: 1131 SL--SPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKTSLEDIDLGSGLFEKP 1188
+ + G E T GS TT ++ S +T T+ + TT T E + E
Sbjct: 235 TKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPT 294
Query: 1189 KATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDM 1248
A+ + +T+ T+ + T ++ + T+ F S + + G ETT+
Sbjct: 295 MASTMGSETTMASTIGPETTKVSTASSEV--TTVFAAGSETIRASTV-----GSETTTVS 347
Query: 1249 VIIGESTSHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALS 1308
E TT I+ ET TD TT++ T + E EA +S
Sbjct: 348 TTGSE-------TTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEA---TTVS 397
Query: 1309 TPQPPASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESKEDEPCSE--ETDPVHD 1366
T +T +S+ ++S+ C+E E V
Sbjct: 398 TTGSETTT-----------------------VSI------TDSETTTTCTEGSEMTAVST 428
Query: 1367 LMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEA 1426
+ E + EI + + ++E + T T + G T E
Sbjct: 429 TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTA-----GSETKTAYTTGSET 483
Query: 1427 AEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETY 1486
A E+ SD++ + T ++T +A +T +TE E T T
Sbjct: 484 TTASNTGLETTTVFTIGSDTTTASTEG---SETTAVSATGSEMTTVSTEGSENTTVSTTG 540
Query: 1487 PETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERD----TEVGHQAHEHTEPVSL 1542
ET+ + G + E T GAE+ T+ T A T VS
Sbjct: 541 SETTTVSTTGLETTTTSTEGSEMTTVSTT--GAETTTDSTEGSGTTAASTAGSETTTVST 598
Query: 1543 FPEESSGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVT 1602
E++ D E+ A +E T T+ T ++ S SE V+
Sbjct: 599 ADSENTTASTADSETTS-ASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVS 657
Query: 1603 LIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEEDEDTMFTMVTDLSQR 1662
G+ + ST E + V +GS + TEGSG T T +S
Sbjct: 658 TTGSE--RTITST-----EGSETTTVSATGSETTVSTEGSGTTTVSITGSET--TKVSTT 708
Query: 1663 NTTDTLITLDTSRIITESFFEVPATTIYP-------VSEQPSAKVVPTKFVSETDTSEWI 1715
+ T+ + + S I T S TT S + S + SET T+
Sbjct: 709 GSETTITSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768
Query: 1716 SSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELESPNVA--TSSDSGTRKSF 1773
SS T E T + ST S + E +A T+S++ T +
Sbjct: 769 SSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTA 828
Query: 1774 MSLTTPTQ---SEREMTDSTPVFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLPRSPAS 1830
S T P SE T ST +ET T G++TT S+ + AS
Sbjct: 829 GSETIPASTAGSETTTTTSTEG-SETTTASTEGSETTTASTESSETTTATTIGSETTTAS 887
Query: 1831 VFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEVAGTLSPHVETTF-STEPTGLVLST 1889
+ + + ETTT S+ + E + ETT STE + L T
Sbjct: 888 TEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSEL---T 944
Query: 1890 VMDRVVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPLEEDFSGDFREYSTVSHPIA 1949
+ +E IT ++ SE G+E ST E +TVS +
Sbjct: 945 TVSTTGSETITVSAEG---SETTTVTTMGSETTTASTAGS----------ETTTVSTAGS 991
Query: 1950 KEETVMMEGSGDAAFRDTQTSPSTVPTSVHISHISDSEGPSSTMVSTSAFPW-------- 2001
+ T +EGS T + +TV T+ + I+ +EG +T V+T+
Sbjct: 992 ETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1051
Query: 2002 EEFTSSAEGSGEQLVTVSSSVVPVLPSAVQKFSGTASSIIDEGLGEVGTVNEIDRRSTIL 2061
E T+S EGS + TVS++ ++ T S G T +
Sbjct: 1052 ETTTTSTEGS--ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTA------GSET 1103
Query: 2062 PTAEVEGTKAPVEKEEVKVSGTVSTNFPQTIEPAKLWSRQEVNPVRQEIESETTSEEQIQ 2121
T + G+K E + TVST +T + S E+ V + SETT+ I
Sbjct: 1104 TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGS--EMTTVFTTV-SETTTVSTIG 1160
Query: 2122 EEKSFESPQNSPATEQTIFDSQTFTETEL--KTTDYSVLTTKKTYSDDKEMKEEDTSLVN 2179
E + S S AT + S+T T + +TT S ++ T + +
Sbjct: 1161 SEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTG 1220
Query: 2180 MSTPDPDANGLESYT 2194
T P + G E+ T
Sbjct: 1221 SETSTPSSAGSETNT 1235
Score = 102 bits (253), Expect = 8e-21
Identities = 281/1348 (20%), Positives = 452/1348 (33%), Gaps = 170/1348 (12%)
Query: 522 TARMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVIT 581
TA M T S + + TG + E T + S E+T+ E T
Sbjct: 87 TASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTT 146
Query: 582 VSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGKYLS 641
VS +T + D E+ +ASTT S + GS IT G +
Sbjct: 147 VSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSE-----------TITPSTAGSETT 195
Query: 642 TTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTH-RRERTETLIPEMRTDTYT 700
T T + T ++ +E T +ET + ++T
Sbjct: 196 TVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTA 255
Query: 701 DEIQEEITKSPFM--GKTEEEVFSGMK---LSTSLSEPIHVTESSVEMTKSFDFPTLITK 755
++ T + F KT +G + ST+ SEP + E T + TK
Sbjct: 256 ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTK 315
Query: 756 LSAEPTEVRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPL 815
+S +EV + + T + TTV + + S+ S D +
Sbjct: 316 VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTT 375
Query: 816 ESTEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDEDIAA 875
STE S + TT G + S T ++ T E ++ +
Sbjct: 376 ASTEGSET--------TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVS 427
Query: 876 HGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSK 935
T F+ TT++ E S + ++T + STEG T+ + +K
Sbjct: 428 ----TTVFETTTAS--TEGSEITIASTSDSETTTASTEGSETTTVTTAG-------SETK 474
Query: 936 PVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWGVLVPSVPSEDE 995
T T+ GL + + TT + + +V V + SE+
Sbjct: 475 TAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENT 534
Query: 996 VLGEPSQDILVIDQTRLEATISPETMRTTKITEGT--TQEEFPWKEQTAEKPVPALSSTA 1053
+ + + T LE TT TEG+ T E T + + ++ A
Sbjct: 535 TVSTTGSETTTVSTTGLET--------TTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA 586
Query: 1054 WTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKIDHSVSYPPGAVTEHK 1113
T T + + + + + ++ E + S T + + + G+ T
Sbjct: 587 STAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTV 646
Query: 1114 VKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEETTTEKT 1173
TD T+ G + +++ TEGS TT T S + T ++ TTT
Sbjct: 647 STTDSETTMVSTTGSERTIT-------STEGSETT--TVSATGSETTVSTEGSGTTTVSI 697
Query: 1174 SLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSSAITKKP 1233
+ GS E K + +TI T S+ITTA S+ TT+A S T
Sbjct: 698 T------GS---ETTKVSTTGSETTITSTEGSEITTA--SITGSETTTASTEGSETTTA- 745
Query: 1234 PLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKETETDIDREYFTTSSPPATQPTRP 1293
G ETTS ST+ TT ++ T I T +S ++ T+
Sbjct: 746 ----STEGSETTS------ASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTK- 794
Query: 1294 PTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEVRENKTGRMSDLSVIGHPIDSESKE 1353
+ST +T F EN SE+
Sbjct: 795 -------------VSTASSKMTTVF-----------TEN----------------SETTI 814
Query: 1354 DEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPSVQYING 1413
+ ET V +E +P E S E E ++ TTT S +
Sbjct: 815 ASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE-TTTASTESSET 873
Query: 1414 KHLVT----TVPKDPEAAEARRGQFESVAPSQNFSDSSESDTHPFVIAKTELSTAVQPNE 1469
T T E +E E + ++ SE T ++T ++
Sbjct: 874 TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933
Query: 1470 STETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEV 1529
+T +TE E+T T ET + G T E + TA +V+ +E
Sbjct: 934 TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993
Query: 1530 GHQAHEHTEPVSLFPEES-SGEIAIDQESQKIAFARATEVTFGEEVEKSTSVTYTPTIVP 1588
+ E +E ++ S + ++ I +E T T+ YT
Sbjct: 994 TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSET 1053
Query: 1589 SSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGSSSIPITEGSGEAEED 1648
++ S SE V+ G+ + + + +E T V SGS T + A +
Sbjct: 1054 TTTSTEGSETTTVSTTGS----ETTTASTADLETT---TVSTSGSG----TTTASTAGSE 1102
Query: 1649 EDTMF---TMVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKF 1705
T++ + T S + T ++ +S T S TT++
Sbjct: 1103 TTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT------------- 1149
Query: 1706 VSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELESPNVATSS 1765
VSET T I S E TT T + +ST S E+ +T+
Sbjct: 1150 VSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGS---------ETTTASTAG 1200
Query: 1766 DSGTRKSFMSLTTPTQSEREMTDSTP--VFTETNTLENLGAQTTEHSSIHQPGVQEGLTT 1823
T S T T STP +ETNT +G++TT S+ ++ T+
Sbjct: 1201 SETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIAST---ASLEPTATS 1257
Query: 1824 LPRSPASVFMEQGSGEAAADPETTTVSS 1851
L S + SG AA +TTVSS
Sbjct: 1258 LTGSETTTVSITASGATAA---STTVSS 1282
Score = 100 bits (249), Expect = 2e-20
Identities = 275/1314 (20%), Positives = 439/1314 (33%), Gaps = 135/1314 (10%)
Query: 678 TEMTHRRERTETLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKL---STSLSEPI 734
T T E T LI T T + E T SP +T SG ++ ST+ SE
Sbjct: 17 TASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENT 76
Query: 735 HVTE------------SSVEMTKSFDFPTLITKLSAEPTEVRDMEEDFTATPGTTKYDEN 782
V+ S ++ + T ++ E T V M + T T TT +
Sbjct: 77 TVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSE-TTTNSTTSSETT 135
Query: 783 ITTVLLAHGTL--SVEAATVSKWSWDED----NTTSKPLESTEPSASSKLPPALL----- 831
+T+ + T +V + T + ++ D + +TT + + + S + P+
Sbjct: 136 VTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETT 195
Query: 832 ---------TTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDEDIAAHGKFTIR 882
TTV G + S + + T K ++ ++ G
Sbjct: 196 TVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS---- 251
Query: 883 FQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLSKPVSTVPQ 942
T+ E S + TE+ ST G + T S G + ++ + +
Sbjct: 252 ---ETTAASTEDSETNTAFTEDSKTTTASTTG--FETTAASTTGS--EPTMASTMGSETT 304
Query: 943 FAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVI-PKTDWGVLVPSVPSEDEVLG-EP 1000
A T E VS +S++ T + S TI S + +T S + ++G E
Sbjct: 305 MASTIGPETTK-VSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSET 363
Query: 1001 SQDILVIDQTRLEATISPETMRTTKITEGT--TQEEFPWKEQTAEKPVPALSSTAWTPKE 1058
S D +T +T ET TT TEG+ T E T + ++T T
Sbjct: 364 STDSTTGSETTTASTEGSET--TTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGS 421
Query: 1059 AVTPLDEQ-------EGDGSAYTV---SEDELLTGSERVPVLETTPVGKIDHSVSYPPGA 1108
+T + +GS T+ S+ E T S T + +Y G+
Sbjct: 422 EMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGS 481
Query: 1109 VTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHITQLMEET 1168
T T T IG + + TEGS TT +++ S +T T+ E T
Sbjct: 482 ETTTASNTGLETTTVFTIGSDTTTA-------STEGSETTAVSATGSEMTTVSTEGSENT 534
Query: 1169 TTEKTSLEDIDLGS-GLFEKPKATELIEFSTIKVTVPSDITTAFSSVDRLHTTSAFKPSS 1227
T T E + + GL +TE E +T+ T T S + TT+A S
Sbjct: 535 TVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT---GAETTTDSTEGSGTTAASTAGS 591
Query: 1228 AITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAKETETDIDREYFTTSSPPA 1287
T D E +T+D ST+ TT ++ T + TT S
Sbjct: 592 ETTTVSTA-DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650
Query: 1288 TQPTRPPTVEDKEAF----GPQALSTP----QPPASTKFHPDINVYIIEVRENKTGRMSD 1339
++ T T + G + + + ST+ V I K
Sbjct: 651 SETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGS 710
Query: 1340 LSVIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANA 1399
+ I SE ET +E + E S E A+
Sbjct: 711 ETTITSTEGSEITTASITGSETTTASTEGSETTTASTEGSETT---SASTTGSETTTAST 767
Query: 1400 TDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQN---FSDSSESDTHPFVI 1456
T TT + + + +T+ + + +V + + ++ S+T
Sbjct: 768 TSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVST 827
Query: 1457 AKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEEFESGTAK 1516
A +E A T TT S E + E SE + T E+ TA
Sbjct: 828 AGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTAS 887
Query: 1517 KGAESVTERDTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVTFGEEVEK 1576
T TE TE + ++G ++ T T G E+
Sbjct: 888 TEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTE--GSETTTASTEGSELT- 944
Query: 1577 STSVTYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESWVEATPRQVVELSGSSSI 1636
+ S T + TI + SA SE VT +G+ T + + V +GS +
Sbjct: 945 TVSTTGSETI---TVSAEGSETTTVTTMGS-------ETTTASTAGSETTTVSTAGSET- 993
Query: 1637 PITEGSGEAEEDEDTMFT--MVTDLSQRNTTDTLITLDTSRIITESFFEVPATTIYPVSE 1694
T S E E T T +S T T+ + + S T + T +Y
Sbjct: 994 --TTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1051
Query: 1695 QPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPF 1754
+ + SET T S T E T T+ + +ST S+ +
Sbjct: 1052 ETTTTSTEG---SETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTV-- 1106
Query: 1755 ELESPNVATSSDSGTRKSFMSLTTPTQSEREMTDS--TPVFT---ETNTLENLGAQTTEH 1809
+ T+S G+ + +S T+ + T S T VFT ET T+ +G++ T
Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTS 1166
Query: 1810 SSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEVAGT 1869
S+ + AS + + + A ETTT S+ A E +
Sbjct: 1167 SAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTP 1226
Query: 1870 LSPHVET--------------TFSTEPTGLVLS---TVMDRVVAENITQTSREI 1906
S ET T S EPT L+ T + A T S +
Sbjct: 1227 SSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTV 1280
Score = 97.8 bits (242), Expect = 2e-19
Identities = 288/1333 (21%), Positives = 455/1333 (34%), Gaps = 171/1333 (12%)
Query: 566 SDESTLIFDQIPEVITVSKTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEER 625
S E+T+ T S T +T ++ E+ +AST S P GS
Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGS-------- 53
Query: 626 QTSGRITEEFLGKYLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRE 685
QT+ G ++TT T + + G T + + T
Sbjct: 54 QTT---IVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSIT 110
Query: 686 RTE-TLIPEMRTDTYTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMT 744
TE T++ M ++T T+ T ST+ SE V+ E T
Sbjct: 111 GTETTMVSAMGSETTTNSTTSSET---------------TVTSTAGSETTTVSTVGSETT 155
Query: 745 KSFDFPTLITKLSAEPTEVRDMEEDFTA-----TPGTTKYDENITTVLLAHGTLSVEAAT 799
++ T ++ +A T +M FTA TP T TTV A + + T
Sbjct: 156 TAY---TADSETTAASTTGSEMTTVFTAGSETITPSTA--GSETTTVSTAGSETTTVSTT 210
Query: 800 VSKWSWDEDNTTSKPLESTEPSASSKLPPA-LLTTVGMNGKDKDIPSFTEDGADEFTLIP 858
S+ + + ST S ++K+ A TTV G + S TED
Sbjct: 211 GSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAAS-TEDSETNTAFTE 269
Query: 859 DSTQKQLEEVTDEDIAAHGKFTIRFQPTTSTGIAEKSTLRDSTTEE--KVPPITSTEGQV 916
DS E AA T +PT ++ + ++T+ + E KV +S V
Sbjct: 270 DSKTTTASTTGFETTAAS---TTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV 326
Query: 917 YA----TMEGSALGEVEDVDLSKPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHT 972
+A T+ S +G + VST T+ + G + S+T TT +
Sbjct: 327 FAAGSETIRASTVGSE-----TTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTE-- 379
Query: 973 IPLSVIPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEATI--SPETMRTTKITEGT 1030
SE + + T E T ++ TT TEG+
Sbjct: 380 ------------------GSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGS 421
Query: 1031 TQEEFPWKEQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVL 1090
E TA ++TA T +T + S+ E T S
Sbjct: 422 --------EMTAVSTTVFETTTASTEGSEIT----------IASTSDSETTTASTEGSET 463
Query: 1091 ETTPVGKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGF 1150
T + +Y G+ T T T IG + + TEGS TT
Sbjct: 464 TTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTA-------STEGSETTAV 516
Query: 1151 TSSLSPFSTHITQLMEETTTEKTSLEDIDLG-SGLFEKPKATELIEFSTIKVTVPSDITT 1209
+++ S +T T+ E TT T E + +GL +TE E +T+ T T
Sbjct: 517 SATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTT---GAET 573
Query: 1210 AFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAK 1269
S + TT+A S T D E +T+D ST+ TT ++
Sbjct: 574 TTDSTEGSGTTAASTAGSE-TTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSE 632
Query: 1270 ETETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEV 1329
T + TT S ++ T T + S ++T ++
Sbjct: 633 TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVS------ 686
Query: 1330 RENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEEN 1389
+ + +S+ G SE+ + ET +EI E +E +
Sbjct: 687 --TEGSGTTTVSITG----SETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGS 740
Query: 1390 EEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSES 1449
E TTT S + G + E A E+ S S+++ +
Sbjct: 741 E------------TTTASTE---GSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785
Query: 1450 DTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEE 1509
T + ++T + +T TE+ E T T ET+ + G + P E
Sbjct: 786 ST---IGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGS-ETIPASTAGSE 841
Query: 1510 FESGTAKKGAESVTERDTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFARATEVT 1569
+ T+ +G+E+ T TE TE E++ I E+ T T
Sbjct: 842 TTTTTSTEGSETTT-ASTEGSETTTASTE-----SSETTTATTIGSET-------TTAST 888
Query: 1570 FGEEVEKSTSVTYTPTIVPSSASAYVSEEEAVTLIGNPW---PDDLLSTKESWVEATPRQ 1626
G E T+ T T ++AS SE V+ G+ + T + E +
Sbjct: 889 EGSE----TTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELT 944
Query: 1627 VVELSGSSSIPITEGSGEAEEDEDTMFTMVTDLSQRNTTDTLITLDTSRIITESFFEVPA 1686
V +GS +I ++ G TM + T S + T ++ S T S
Sbjct: 945 TVSTTGSETITVS-AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET 1003
Query: 1687 TTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQR 1746
TT+ + T VS T T I+ST E G+ TA +T
Sbjct: 1004 TTVSSTGSE-------TTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTT 1056
Query: 1747 SDQLILPFELESPNVATSSDSGTRKSFMSL--TTPTQSEREMTDSTPVFTETNTLENLGA 1804
S + E+ V+T+ T S L TT + S T ++ +ET T+ G+
Sbjct: 1057 STE-----GSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111
Query: 1805 QTTEHSSIHQPGVQEGLTTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEK 1864
+TT S+ T+ + AS + + ETTTVS+ + A
Sbjct: 1112 KTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGS 1171
Query: 1865 EVAGTLSPHVETT 1877
E T + ETT
Sbjct: 1172 EATTTSTEGSETT 1184
Score = 89.7 bits (221), Expect = 4e-17
Identities = 282/1365 (20%), Positives = 465/1365 (34%), Gaps = 134/1365 (9%)
Query: 1707 SETDTSEWISSTTVEEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELESPNVATSSD 1766
S T T+ S T + E T TA + S S I+ + + T+S
Sbjct: 13 SNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIV--SISGSEITTTST 70
Query: 1767 SGTRKSFMS-----LTTPTQSEREMTDSTPVFTETNTLENLGAQTTEHSSIHQPGVQEGL 1821
+G+ + +S TT + + E T ST +ET T+ G +TT S++ G
Sbjct: 71 AGSENTTVSSAGSGTTTASMAGSETTVST-AGSETTTVSITGTETTMVSAM-------GS 122
Query: 1822 TTLPRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEV--AGTLSPHVETTFS 1879
T S S + + + A ETTTVS+ A A+ E A T + T F+
Sbjct: 123 ETTTNSTTS---SETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFT 179
Query: 1880 TEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPLEEDFSGDFR 1939
+ ST T+ SE G+E ST E +
Sbjct: 180 AGSETITPSTAGSET-------TTVSTAGSETTTVSTTGSETTTASTAHS-ETTAASTMG 231
Query: 1940 EYSTVSHPIAKEETVMMEGSGDAAFRDTQTSPSTVPTSVHISHISDSEGPSSTMVSTSAF 1999
+T E TV GS A + +T T + + + G +T ST+
Sbjct: 232 SETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGS 291
Query: 2000 PWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQKFSGTASSIIDEGLGEVGTVNEIDRRST 2059
E +S GS T++S++ P + V S +++ G E + + +T
Sbjct: 292 --EPTMASTMGSE---TTMASTIGPET-TKVSTASSEVTTVFAAG-SETIRASTVGSETT 344
Query: 2060 ILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQTIEPAKLWSRQEVNPVRQEIESETTSEEQ 2119
+ T E T A + E T + E E SETT+
Sbjct: 345 TVSTTGSETTTASIMGSETSTDSTTGS---------------ETTTASTE-GSETTTAST 388
Query: 2120 IQEEKSFESPQNSPATEQTIFDSQTFTE----TELKTTDYSVLTTKKTYSDDKEMKEEDT 2175
E + S S T +I DS+T T +E+ +V T ++ E+ T
Sbjct: 389 EGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIAST 448
Query: 2176 SLVNMSTPDPDANGLESYTTLPEATEKSHFFLATALVTESIPAEHVVTDSPIKKEESTKH 2235
S +T + + + TT T+ TA T S T + E+T
Sbjct: 449 SDSETTTASTEGSETTTVTTAGSETK-------TAYTTGS-----ETTTASNTGLETTTV 496
Query: 2236 FPKGMRPTIQESDTELLFSGLGSGEEVLPTLPTESVNFTEVEQINN--TLYPHTSQVEST 2293
F G T ++ + +G E + T+ TE T V + T T +T
Sbjct: 497 FTIGSDTTTASTEGSETTAVSATGSE-MTTVSTEGSENTTVSTTGSETTTVSTTGLETTT 555
Query: 2294 SSDKIEDFNRMENVAKEVGPLVSQTDIFEGSGSVTSTTL---IEILSDTGAEGPTVAPLP 2350
+S + + + E + TD EGSG+ ++T +S +E T +
Sbjct: 556 TSTEGSEMTTVSTTGAE-----TTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTAD 610
Query: 2351 FSTDIGHPQNQTVRWAEEIQTSRPQTITEQDSNKNSSTAEINETTTSSTDFLARAYGFEM 2410
T A + TE ST + +ETT ST R
Sbjct: 611 SETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD-SETTMVSTTGSERTITSTE 669
Query: 2411 AKEFVTSAPKPSDLYYEPSGEGSGEVDIVDSFHTSATTQATRQESSTTFVS-DGSLEKHP 2469
E T + S+ G G+ V I S TT+ + S TT S +GS
Sbjct: 670 GSETTTVSATGSETTVSTEGSGTTTVSITG----SETTKVSTTGSETTITSTEGSEITTA 725
Query: 2470 EVPSAKAVTA--DGFPTVSVMLPLHSEQNKSSPDPTSTLSNTVSYERSTDGSFQDRFREF 2527
+ ++ TA +G T + + S+ +T ++T S E +T S
Sbjct: 726 SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSE-TTMASIMG----- 779
Query: 2528 EDSTLKPNRKKPTENIIIDLDKEDKDLILTITESTILEILPELTSDKNTIIDIDHTKPVY 2587
++T+ T + K + T+ + T+ + T + ++ +
Sbjct: 780 SETTMASTIGSETTKVSTASSK-----MTTVFTENSETTIASTTASETTTVSTAGSETIP 834
Query: 2588 EDILGMQTDIDTEVP-SEPHDSNDESNDDSTQVQEIYEAAVNLSLTEETFEGSADVLASY 2646
G +T T SE ++ E ++ +T E E ++ ET S + +
Sbjct: 835 ASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETT 894
Query: 2647 TQATHDESMTYEDRSQLDHMGFHFTTGIPAPSTETELDVLLPTATSLPIPRKSATVIPEI 2706
T +T + S T ++ + TTG + TE +T +T E
Sbjct: 895 TTST-EGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSET 953
Query: 2707 EGIKAEAKALDDMFE-SSTLSDGQAIADQSEIIPTLGQFERTQEEYEDKKHAGPSFQPEF 2765
+ AE + S + ++ + T G E T E + S
Sbjct: 954 ITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGS-ETTTASIEGSETTTVS----- 1007
Query: 2766 SSGAEEALVDHTPYLSIATTHLMDQSVTEVPDVMEGSNPPYYTDTTLAVSTFAKLSSQTP 2825
S+G+E V T + T+ + S T YT + +T + S T
Sbjct: 1008 STGSETTTVSTTGTETTITS--TEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTT 1065
Query: 2826 SSPLTIYSGSE-ASGHTEIPQPSALPGIDVGSSVMSPQDS-FKEIHVNIEATFKPSSEEY 2883
S +GSE + T + + + G++ S S +++ T S+E
Sbjct: 1066 VST----TGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGS 1121
Query: 2884 LHITEPPSLSPDTKLEPSEDDGKPELLEEMEASPTELIAVEGTEILQDFQNKTDGQVSGE 2943
T + S T + + E + I E T T G
Sbjct: 1122 EATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGS 1181
Query: 2944 AIKMFPTIKTPEAGTVITTADEIELEGATQWPHSTSASATYGVEAGVVPWLSPQTSERPT 3003
T AG+ TTA E T+ ++T G E +TS +
Sbjct: 1182 -----ETTTASTAGSETTTASTAGSE--------TTTASTSGSETNTACTTGSETSTPSS 1228
Query: 3004 LSSSPEINPETQAALIRGQDSTIAASEQ-QVAARILDSNDQATVN 3047
S ET A I G ++TIA++ + A L ++ TV+
Sbjct: 1229 AGS------ETNTAFIIGSETTIASTASLEPTATSLTGSETTTVS 1267
Score = 62.8 bits (151), Expect = 6e-09
Identities = 178/834 (21%), Positives = 276/834 (33%), Gaps = 120/834 (14%)
Query: 528 ESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVITVSKT-S 586
E+ T S + T G T+ D E ++ E T+ + E TVS T S
Sbjct: 622 ETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGS 681
Query: 587 EDTIHTH--------LEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGK 638
E T+ T + E+ STT S + GS + T+ IT G
Sbjct: 682 ETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEI-------TTASIT----GS 730
Query: 639 YLSTTPFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRERTETLIPEMRTDT 698
+T EG T T T E T T T
Sbjct: 731 ETTTAS--------------------TEGSETT------TASTEGSETTSASTTGSETTT 764
Query: 699 YTDEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMTKSFDFPTLITKLSA 758
E T + MG ST SE V+ +S +MT F + T S
Sbjct: 765 -ASTTSSETTMASIMGS------ETTMASTIGSETTKVSTASSKMTTVFTENSETTIAST 817
Query: 759 EPTEVRDMEEDFTAT-PGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPLES 817
+E + + T P +T E TT S E + + S + TT+ ES
Sbjct: 818 TASETTTVSTAGSETIPASTAGSETTTTT-------STEGSETTTASTEGSETTTASTES 870
Query: 818 TEPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQLEEVTDED---IA 874
+E + ++ + + TT G + S +G++ T + ++ T + +
Sbjct: 871 SETTTATTI-GSETTTASTEGSETTTTS--TEGSETTTASTEGSEITTVSTTGSETTTAS 927
Query: 875 AHGKFTIRFQPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSALGEVEDVDLS 934
G T T ST +E +T+ + +E +E TM +
Sbjct: 928 TEGSET----TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSET 983
Query: 935 KPVSTVPQFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDWG---------- 984
VST T+ +EG + SST TT V ++ T + I T+
Sbjct: 984 TTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGT--ETTITSTEGSETTTVTTAGS 1041
Query: 985 --VLVPSVPSEDEVLGEPSQDILVIDQTRLE-ATISPETMRTTKIT---EGTTQEEFPWK 1038
V + SE + + T E T S + TT ++ GTT
Sbjct: 1042 ETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGS 1101
Query: 1039 EQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKI 1098
E T + ++TA T T + + + + + E+ T V ETT V I
Sbjct: 1102 ETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTT--VFTTVSETTTVSTI 1159
Query: 1099 DHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFS 1158
+ A +E + E T S + T GS TT ++S S +
Sbjct: 1160 GSEATTSSAAGSEATTTSTEGSETT-----TASTAGSETTTASTAGSETTTASTSGSETN 1214
Query: 1159 THITQLMEETTTEKTSLE---------DIDLGSGLFEKPKATELIEFSTIKVTVPSDITT 1209
T T E +T E + + S +P AT L T V++ + T
Sbjct: 1215 TACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGAT 1274
Query: 1210 AFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIVAK 1269
A +S TT ++ ++ +P G TT + S + P A
Sbjct: 1275 A-ASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAAS 1333
Query: 1270 ETETDI--DREYFTTSSPPA------------TQPTRPPTVEDKEAFGPQALST 1309
T I + TS+ A T TR PT + GP ++ T
Sbjct: 1334 HTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGT 1387
>gi|110624774 mannose receptor, C type 2 [Homo sapiens]
Length = 1479
Score = 109 bits (272), Expect = 5e-23
Identities = 50/126 (39%), Positives = 73/126 (57%), Gaps = 4/126 (3%)
Query: 3169 CDYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNR-VGHDYQ--W 3225
C+ W FQG CY+ A +R+W +++ C G L SI S E F+ + + + + W
Sbjct: 382 CEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSIHSMAELEFITKQIKQEVEELW 441
Query: 3226 IGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYHL 3285
IGLND + +F W+DGS + + +W P +P++F + EDCV IW G+WND PCN L
Sbjct: 442 IGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVT-IWGPEGRWNDSPCNQSL 500
Query: 3286 TYTCKK 3291
CKK
Sbjct: 501 PSICKK 506
Score = 87.4 bits (215), Expect = 2e-16
Identities = 51/144 (35%), Positives = 71/144 (49%), Gaps = 8/144 (5%)
Query: 3162 CEQDTETCDYGWHKFQ--GQCYKY-FAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNR 3218
C + C+ W K Q CY++ F +W A C QGA L SI EQ ++N
Sbjct: 228 CPIKSNDCETFWDKDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYING 287
Query: 3219 VGHDYQ---WIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQ 3275
+ Y WIGLND ++W+D S L+Y NW +QPD+ + E+C VI +G
Sbjct: 288 LLTGYSSTLWIGLNDLDTSGGWQWSDNSPLKYLNWESDQPDN--PSEENCGVIRTESSGG 345
Query: 3276 WNDVPCNYHLTYTCKKGTVACGQP 3299
W + C+ L Y CKK A +P
Sbjct: 346 WQNRDCSIALPYVCKKKPNATAEP 369
Score = 79.0 bits (193), Expect = 8e-14
Identities = 51/139 (36%), Positives = 66/139 (47%), Gaps = 16/139 (11%)
Query: 3173 WHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSI--------LSHEEQMFVNRVGHDYQ 3224
W +FQ YK+F H TW A+R C A LTS+ LSH Q F +R +
Sbjct: 829 WLRFQEAEYKFFEHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKF-SRAQEQHW 887
Query: 3225 WIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGED--CVVIIWHENGQWNDVPCN 3282
WIGL+ + FRWTDGS + + +W P +P G+D CV + W D C
Sbjct: 888 WIGLHTSESDGRFRWTDGSIINFISWAPGKPR---PVGKDKKCVYMT-ASREDWGDQRCL 943
Query: 3283 YHLTYTCKKGTVAC-GQPP 3300
L Y CK+ V QPP
Sbjct: 944 TALPYICKRSNVTKETQPP 962
Score = 60.8 bits (146), Expect = 2e-08
Identities = 42/143 (29%), Positives = 61/143 (42%), Gaps = 21/143 (14%)
Query: 3169 CDYGWHKFQGQCYKYFAH----RRTWDAAERECRLQGAHLTSILSHEEQMFVN----RVG 3220
C W +F +C++ R W A+ C Q A L +I + EQ F+ V
Sbjct: 972 CPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQAFITASLPNVT 1031
Query: 3221 HDYQWIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGE-----DCVVIIW----H 3271
D WIGL+ + DF+W + L Y NW P +P A C V++ H
Sbjct: 1032 FDL-WIGLHAS--QRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAVVLHSPSAH 1088
Query: 3272 ENGQWNDVPCNYHL-TYTCKKGT 3293
G+W+D C + C+KGT
Sbjct: 1089 FTGRWDDRSCTEETHGFICQKGT 1111
Score = 53.9 bits (128), Expect = 3e-06
Identities = 44/147 (29%), Positives = 66/147 (44%), Gaps = 25/147 (17%)
Query: 3166 TETCDYGWHKFQG--QCYKYFAHRR-----TWDAAERECRLQGAHLTSILSHEEQMFV-- 3216
T +C GW CYK F+ R +W A+ C+ GA L S+ S+EE+ FV
Sbjct: 666 TGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEEHFVAN 725
Query: 3217 --NRVGHDYQ---------WIGLN--DKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGE 3263
N++ + + WIGLN D +RW+DG Y N+ ++ D G
Sbjct: 726 MLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRG- 784
Query: 3264 DCVVIIWHENGQWNDVPCNYHLTYTCK 3290
C V+ + QW + C+ L + CK
Sbjct: 785 -CAVLDL-ASLQWVAMQCDTQLDWICK 809
Score = 53.5 bits (127), Expect = 3e-06
Identities = 34/133 (25%), Positives = 54/133 (40%), Gaps = 7/133 (5%)
Query: 3164 QDTETCDYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGH-- 3221
++ C GW CY + T+ A R C G+ L +I + EQ FV+ + +
Sbjct: 516 EEDHGCRKGWTWHSPSCYWLGEDQVTYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNW 575
Query: 3222 --DYQWIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDV 3279
+Y W L D F W G + Y +W +QP +S G + G W
Sbjct: 576 EGEYFWTALQDLNSTGSFFWLSGDEVMYTHWNRDQPG--YSRGGCVALATGSAMGLWEVK 633
Query: 3280 PC-NYHLTYTCKK 3291
C ++ Y C++
Sbjct: 634 NCTSFRARYICRQ 646
Score = 43.1 bits (100), Expect = 0.005
Identities = 38/147 (25%), Positives = 54/147 (36%), Gaps = 20/147 (13%)
Query: 3156 SYVGALCEQDTETCDYGWHKFQGQCYKY-----FAHRRTWDAAERECRLQGAHLTSILSH 3210
SY G+ C Q D W F+ CY + H+ A + C+ G + SIL
Sbjct: 1256 SYHGS-CPQGL--ADSAWIPFREHCYSFHMELLLGHKE----ARQRCQRAGGAVLSILDE 1308
Query: 3211 EEQMFVNRVGHDYQ------WIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGED 3264
E +FV Y+ W+G+N W D + + Y NW P +
Sbjct: 1309 MENVFVWEHLQSYEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNS 1368
Query: 3265 CVVIIWHENGQWNDVPC-NYHLTYTCK 3290
C I +G W C N + CK
Sbjct: 1369 C-YWIQSNSGLWRPGACTNITMGVVCK 1394
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 108 bits (271), Expect = 7e-23
Identities = 45/93 (48%), Positives = 57/93 (61%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C PC+N G C+ T+ SY+C C PG+SG CE D D+C +NPC+NG +C+DG NTF
Sbjct: 875 DECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNTFS 934
Query: 3151 CLCLPSYVGALCEQDTETCDYGWHKFQGQCYKY 3183
CLCLP + G C+ D C K G C Y
Sbjct: 935 CLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDY 967
Score = 99.8 bits (247), Expect = 4e-20
Identities = 43/91 (47%), Positives = 52/91 (57%), Gaps = 1/91 (1%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C NPC +G TC Y C CVPGY G CE + DEC + PC+NG TC+D N F+
Sbjct: 1151 DECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFK 1210
Query: 3151 CLCLPSYVGALCEQDTETCDYGWHKFQ-GQC 3180
C C P G LCE++ + C G H GQC
Sbjct: 1211 CSCPPGTRGLLCEENIDDCARGPHCLNGGQC 1241
Score = 96.7 bits (239), Expect = 4e-19
Identities = 40/93 (43%), Positives = 55/93 (59%), Gaps = 3/93 (3%)
Query: 3091 DRCKM---NPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFN 3147
D C M NPC + G C T+ ++ C C+ GY+G +CE+D +ECHS+PC+N ATC+D
Sbjct: 417 DECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIG 476
Query: 3148 TFRCLCLPSYVGALCEQDTETCDYGWHKFQGQC 3180
F CLC+P + G CE + C GQC
Sbjct: 477 GFTCLCMPGFKGVHCELEINECQSNPCVNNGQC 509
Score = 94.0 bits (232), Expect = 2e-18
Identities = 36/87 (41%), Positives = 55/87 (63%), Gaps = 5/87 (5%)
Query: 3084 AIYLPGPDRCKMNPCLNGGTCYPT-ETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATC 3142
++Y+P C +PC+NGGTC T + ++ C C+PG+ G CE + D+C ++ C+NG C
Sbjct: 220 SLYVP----CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVC 275
Query: 3143 VDGFNTFRCLCLPSYVGALCEQDTETC 3169
VDG NT+ C C P + G C +D + C
Sbjct: 276 VDGVNTYNCRCPPQWTGQFCTEDVDEC 302
Score = 93.2 bits (230), Expect = 4e-18
Identities = 33/80 (41%), Positives = 48/80 (60%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
+ C+ NPC+N G C + C C PG++G C++D D+C S PC NGA C+D N +
Sbjct: 496 NECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYE 555
Query: 3151 CLCLPSYVGALCEQDTETCD 3170
C C + G LCE++ + CD
Sbjct: 556 CQCATGFTGVLCEENIDNCD 575
Score = 91.3 bits (225), Expect = 1e-17
Identities = 34/79 (43%), Positives = 48/79 (60%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C NPC NGG+C ++ C C+PG++GD+C+ D +EC S PC+NG TC D N++
Sbjct: 913 DDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYT 972
Query: 3151 CLCLPSYVGALCEQDTETC 3169
C C + G CE + C
Sbjct: 973 CKCQAGFDGVHCENNINEC 991
Score = 90.5 bits (223), Expect = 3e-17
Identities = 34/79 (43%), Positives = 46/79 (58%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
+ C +PC N TC + C C+PG+ G CEL+ +EC SNPC N CVD N F+
Sbjct: 458 NECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQ 517
Query: 3151 CLCLPSYVGALCEQDTETC 3169
CLC P + G +C+ D + C
Sbjct: 518 CLCPPGFTGPVCQIDIDDC 536
Score = 89.7 bits (221), Expect = 4e-17
Identities = 36/79 (45%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C +PCLN G C Y C C PG SG CE++FD+C SNPC +G C+DG N +
Sbjct: 609 DECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHG-ICMDGINRYS 667
Query: 3151 CLCLPSYVGALCEQDTETC 3169
C+C P + G C D + C
Sbjct: 668 CVCSPGFTGQRCNIDIDEC 686
Score = 85.5 bits (210), Expect = 8e-16
Identities = 34/79 (43%), Positives = 43/79 (54%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
+ C PC NGGTC SY C C G+ G CE + +EC + C NG TCVDG N+F
Sbjct: 951 NECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFS 1010
Query: 3151 CLCLPSYVGALCEQDTETC 3169
CLC + G+ C + C
Sbjct: 1011 CLCPVGFTGSFCLHEINEC 1029
Score = 85.1 bits (209), Expect = 1e-15
Identities = 33/63 (52%), Positives = 42/63 (66%), Gaps = 1/63 (1%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C NPC++G C Y C C PG++G +C +D DEC SNPCR GATC++G N FR
Sbjct: 647 DDCASNPCIHG-ICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFR 705
Query: 3151 CLC 3153
C+C
Sbjct: 706 CIC 708
Score = 82.0 bits (201), Expect = 9e-15
Identities = 36/79 (45%), Positives = 46/79 (58%), Gaps = 2/79 (2%)
Query: 3097 PCLNGGTCYP-TETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLP 3155
PCLNGGTC+ + +Y CTC G++G +C+ D C S+PC NG+TC N F C CL
Sbjct: 114 PCLNGGTCHMLSRDTYECTCQVGFTGKECQWT-DACLSHPCANGSTCTTVANQFSCKCLT 172
Query: 3156 SYVGALCEQDTETCDYGWH 3174
+ G CE D CD H
Sbjct: 173 GFTGQKCETDVNECDIPGH 191
Score = 81.6 bits (200), Expect = 1e-14
Identities = 31/79 (39%), Positives = 43/79 (54%), Gaps = 1/79 (1%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C PCLNG C Y C C G++G CE + D C +PC +G C DG +++
Sbjct: 534 DDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG-QCQDGIDSYT 592
Query: 3151 CLCLPSYVGALCEQDTETC 3169
C+C P Y+GA+C + C
Sbjct: 593 CICNPGYMGAICSDQIDEC 611
Score = 81.3 bits (199), Expect = 2e-14
Identities = 33/79 (41%), Positives = 42/79 (53%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
+ C NPC NGGTC Y CTC G+ G C+++ DEC SNPC N TC D + +
Sbjct: 759 NECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYT 818
Query: 3151 CLCLPSYVGALCEQDTETC 3169
C C+ Y G C+ C
Sbjct: 819 CHCVLPYTGKNCQTVLAPC 837
Score = 80.9 bits (198), Expect = 2e-14
Identities = 35/90 (38%), Positives = 46/90 (51%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
+ C + C NGGTC S+ C C G++G C + +EC S+PC N TCVDG T+R
Sbjct: 989 NECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYR 1048
Query: 3151 CLCLPSYVGALCEQDTETCDYGWHKFQGQC 3180
C C Y G C+ C K +G C
Sbjct: 1049 CSCPLGYTGKNCQTLVNLCSRSPCKNKGTC 1078
Score = 80.1 bits (196), Expect = 3e-14
Identities = 33/81 (40%), Positives = 42/81 (51%), Gaps = 2/81 (2%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVD--GFNT 3148
D C NPCLN GTC+ + Y C CV Y+G C+ C NPC N A C + F +
Sbjct: 797 DECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFES 856
Query: 3149 FRCLCLPSYVGALCEQDTETC 3169
+ CLC P + G C D + C
Sbjct: 857 YTCLCAPGWQGQRCTIDIDEC 877
Score = 80.1 bits (196), Expect = 3e-14
Identities = 34/89 (38%), Positives = 45/89 (50%)
Query: 3098 CLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPSY 3157
C + G C ++ C C GY+G CE DEC SNPC++GATC D +RC C+P Y
Sbjct: 1120 CQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGY 1179
Query: 3158 VGALCEQDTETCDYGWHKFQGQCYKYFAH 3186
G CE + + C + G C H
Sbjct: 1180 QGVNCEYEVDECQNQPCQNGGTCIDLVNH 1208
Score = 78.6 bits (192), Expect = 1e-13
Identities = 36/84 (42%), Positives = 40/84 (47%), Gaps = 5/84 (5%)
Query: 3091 DRCKMNPCLNGGTC--YPTETSYVCTCVPGYSGDQCELDFDEC---HSNPCRNGATCVDG 3145
D C NPC G C P Y+CTC GY G C D DEC +SNPC + CV+
Sbjct: 377 DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAGKCVNT 436
Query: 3146 FNTFRCLCLPSYVGALCEQDTETC 3169
F C CL Y G CE D C
Sbjct: 437 DGAFHCECLKGYAGPRCEMDINEC 460
Score = 75.1 bits (183), Expect = 1e-12
Identities = 34/91 (37%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
+ C NPC++G C + Y C C G+ G CE+D +EC SNPC+NG TC + N +R
Sbjct: 722 NECLSNPCIHGN-CTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYR 780
Query: 3151 CLCLPSYVGALCEQDTETCDYGWHKFQGQCY 3181
C C + G C+ + + C QG C+
Sbjct: 781 CTCKKGFKGYNCQVNIDECASNPCLNQGTCF 811
Score = 74.7 bits (182), Expect = 1e-12
Identities = 34/87 (39%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query: 3091 DRCKMNP--CLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNT 3148
D C + P C NGGTC Y C CV G+SGD C + D+C C G+TC+D +
Sbjct: 300 DECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVAS 359
Query: 3149 FRCLCLPSYVGALCEQDTETCDYGWHK 3175
F C+C G LC D HK
Sbjct: 360 FSCMCPEGKAGLLCHLDDACISNPCHK 386
Score = 74.3 bits (181), Expect = 2e-12
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 3/82 (3%)
Query: 3091 DRCKMNP-CLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGAT--CVDGFN 3147
D C P CLNGG C Y C C+PG++G++CE D +EC SNPC + + C+ N
Sbjct: 1227 DDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTN 1286
Query: 3148 TFRCLCLPSYVGALCEQDTETC 3169
+ C+C ++ G CE + C
Sbjct: 1287 DYLCVCRSAFTGRHCETFVDVC 1308
Score = 72.8 bits (177), Expect = 5e-12
Identities = 32/79 (40%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C +PC + G C SY C C PGY G C DEC+S+PC N C+D N ++
Sbjct: 572 DNCDPDPC-HHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQ 630
Query: 3151 CLCLPSYVGALCEQDTETC 3169
C C P G CE + + C
Sbjct: 631 CNCQPGTSGVNCEINFDDC 649
Score = 72.4 bits (176), Expect = 7e-12
Identities = 30/80 (37%), Positives = 43/80 (53%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
+ C +PCLN GTC +Y C+C GY+G C+ + C +PC+N TCV +
Sbjct: 1027 NECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQ 1086
Query: 3151 CLCLPSYVGALCEQDTETCD 3170
CLC + GA C+ +CD
Sbjct: 1087 CLCPSGWAGAYCDVPNVSCD 1106
Score = 69.7 bits (169), Expect = 5e-11
Identities = 30/73 (41%), Positives = 41/73 (56%), Gaps = 1/73 (1%)
Query: 3098 CLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATC-VDGFNTFRCLCLPS 3156
C +GGTC SY C C G++G C+ + C +PC NG TC G TF C CLP
Sbjct: 192 CQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPG 251
Query: 3157 YVGALCEQDTETC 3169
+ G+ CE++ + C
Sbjct: 252 FEGSTCERNIDDC 264
Score = 66.6 bits (161), Expect = 4e-10
Identities = 25/74 (33%), Positives = 41/74 (55%), Gaps = 1/74 (1%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECH-SNPCRNGATCVDGFNTF 3149
D C +PC NG TC + C C+ G++G +CE D +EC C++G TC++ ++
Sbjct: 146 DACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNLPGSY 205
Query: 3150 RCLCLPSYVGALCE 3163
+C C + G C+
Sbjct: 206 QCQCPQGFTGQYCD 219
Score = 66.6 bits (161), Expect = 4e-10
Identities = 30/79 (37%), Positives = 37/79 (46%), Gaps = 1/79 (1%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C NPC G TC + C C G C +EC SNPC +G C G + ++
Sbjct: 684 DECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHG-NCTGGLSGYK 742
Query: 3151 CLCLPSYVGALCEQDTETC 3169
CLC +VG CE D C
Sbjct: 743 CLCDAGWVGINCEVDKNEC 761
Score = 66.2 bits (160), Expect = 5e-10
Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDEC--HSNPCRNGATCVDGFNT 3148
D C + C NGG C +Y C C P ++G C D DEC N C+NG TC +
Sbjct: 262 DDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGG 321
Query: 3149 FRCLCLPSYVGALCEQDTETCDY 3171
+ C+C+ + G C ++ + C +
Sbjct: 322 YGCVCVNGWSGDDCSENIDDCAF 344
Score = 44.3 bits (103), Expect = 0.002
Identities = 31/128 (24%), Positives = 48/128 (37%), Gaps = 16/128 (12%)
Query: 3079 SVEGTAIYLPGPDRCKM----NPCLNGGTCYPTETS--YVCTCVPGYSGDQCELDFDECH 3132
+ G + P P C+ +PC +GG+C+P Y C C P +SG +CEL
Sbjct: 1360 TASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCEL----YT 1415
Query: 3133 SNPCRNGATCVDGFNTFRC---LCLPSYVGALCEQDTETCDYGWHKFQGQCYKYFAHRRT 3189
+ P ATC+ + + +C + C+ D C C
Sbjct: 1416 APPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLP---C 1472
Query: 3190 WDAAEREC 3197
WD +C
Sbjct: 1473 WDYINNQC 1480
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 97.4 bits (241), Expect = 2e-19
Identities = 36/78 (46%), Positives = 50/78 (64%), Gaps = 1/78 (1%)
Query: 3093 CKMNPCLNGGTCYPT-ETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRC 3151
C +PC NGGTC PT + ++ C C+PG++G CE + D+C N C+NG CVDG NT+ C
Sbjct: 222 CSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNC 281
Query: 3152 LCLPSYVGALCEQDTETC 3169
C P + G C +D + C
Sbjct: 282 RCPPEWTGQYCTEDVDEC 299
Score = 96.3 bits (238), Expect = 5e-19
Identities = 40/92 (43%), Positives = 56/92 (60%), Gaps = 2/92 (2%)
Query: 3091 DRCKM--NPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNT 3148
D C + NPC + G C T S+ C C+ GY+G +CE+D +EC SNPC+N ATC+D
Sbjct: 414 DECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGE 473
Query: 3149 FRCLCLPSYVGALCEQDTETCDYGWHKFQGQC 3180
F+C+C+P Y G CE +T+ C G+C
Sbjct: 474 FQCICMPGYEGVHCEVNTDECASSPCLHNGRC 505
Score = 95.9 bits (237), Expect = 6e-19
Identities = 37/79 (46%), Positives = 46/79 (58%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
+ C ++PC +G +C T Y C C GYSG CE D D+C NPC NG +C DG NT
Sbjct: 871 NECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAF 930
Query: 3151 CLCLPSYVGALCEQDTETC 3169
C CLP + G CE+D C
Sbjct: 931 CDCLPGFRGTFCEEDINEC 949
Score = 94.0 bits (232), Expect = 2e-18
Identities = 36/80 (45%), Positives = 47/80 (58%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C +PCL+ G C + C C G++G C+ D DEC S PC+NGA C+DG NT+
Sbjct: 492 DECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYT 551
Query: 3151 CLCLPSYVGALCEQDTETCD 3170
C+C Y G CE D + CD
Sbjct: 552 CVCTEGYTGTHCEVDIDECD 571
Score = 93.6 bits (231), Expect = 3e-18
Identities = 39/90 (43%), Positives = 52/90 (57%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
+ C+ NPC+NGGTC + YVCTC G+SG C+ + +EC SNPC N TC+D ++
Sbjct: 755 NECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYK 814
Query: 3151 CLCLPSYVGALCEQDTETCDYGWHKFQGQC 3180
C CL Y GA CE C + G+C
Sbjct: 815 CNCLLPYTGATCEVVLAPCAPSPCRNGGEC 844
Score = 92.4 bits (228), Expect = 7e-18
Identities = 36/80 (45%), Positives = 46/80 (57%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
+ C +PC NG C SY CTC G+SG CE + +C + C NG TCVDG N+F
Sbjct: 947 NECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFT 1006
Query: 3151 CLCLPSYVGALCEQDTETCD 3170
CLC P + G+ C+ D CD
Sbjct: 1007 CLCPPGFTGSYCQHDVNECD 1026
Score = 89.4 bits (220), Expect = 6e-17
Identities = 38/93 (40%), Positives = 51/93 (54%), Gaps = 1/93 (1%)
Query: 3090 PDRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTF 3149
PD C + C NGGTC S+ C C PG++G C+ D +EC S PC +G TC DG ++
Sbjct: 985 PD-CTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSY 1043
Query: 3150 RCLCLPSYVGALCEQDTETCDYGWHKFQGQCYK 3182
RC C Y G C+ CD K G+C++
Sbjct: 1044 RCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQ 1076
Score = 89.0 bits (219), Expect = 7e-17
Identities = 38/90 (42%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C PC NG C +Y C C GY+G CE+D DEC +PC G +C DG TF
Sbjct: 530 DECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG-SCKDGVATFT 588
Query: 3151 CLCLPSYVGALCEQDTETCDYGWHKFQGQC 3180
CLC P Y G CE + C + G C
Sbjct: 589 CLCRPGYTGHHCETNINECSSQPCRHGGTC 618
Score = 83.6 bits (205), Expect = 3e-15
Identities = 34/81 (41%), Positives = 45/81 (55%), Gaps = 2/81 (2%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNP--CRNGATCVDGFNT 3148
D C NPC NGG C P E SY+C C P + G C D +EC P CR+G TC + +
Sbjct: 142 DPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGS 201
Query: 3149 FRCLCLPSYVGALCEQDTETC 3169
+RC+C ++ G CE+ C
Sbjct: 202 YRCVCRATHTGPNCERPYVPC 222
Score = 83.6 bits (205), Expect = 3e-15
Identities = 32/79 (40%), Positives = 44/79 (55%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
+ C NPC N TC + C C+PGY G CE++ DEC S+PC + C+D N F+
Sbjct: 454 NECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQ 513
Query: 3151 CLCLPSYVGALCEQDTETC 3169
C C + G LC+ D + C
Sbjct: 514 CECPTGFTGHLCQYDVDEC 532
Score = 83.6 bits (205), Expect = 3e-15
Identities = 34/80 (42%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C +PC + GTC Y C C PGY+G C ++ DEC NPC NG TC DG N F
Sbjct: 643 DDCASSPC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFT 701
Query: 3151 CLCLPSYVGALCEQDTETCD 3170
C C Y C + C+
Sbjct: 702 CRCPEGYHDPTCLSEVNECN 721
Score = 83.6 bits (205), Expect = 3e-15
Identities = 35/80 (43%), Positives = 45/80 (56%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C +PC NG TC Y C CV GY G C + DEC S+PC+NG TC+D NT++
Sbjct: 1147 DECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYK 1206
Query: 3151 CLCLPSYVGALCEQDTETCD 3170
C C G CE + + C+
Sbjct: 1207 CSCPRGTQGVHCEINVDDCN 1226
Score = 83.2 bits (204), Expect = 4e-15
Identities = 30/79 (37%), Positives = 49/79 (62%), Gaps = 1/79 (1%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
+ C PC +GGTC + +Y+C C+ G +G CE++ D+C S+PC +G TC+D + +
Sbjct: 605 NECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSG-TCLDKIDGYE 663
Query: 3151 CLCLPSYVGALCEQDTETC 3169
C C P Y G++C + + C
Sbjct: 664 CACEPGYTGSMCNINIDEC 682
Score = 81.3 bits (199), Expect = 2e-14
Identities = 42/103 (40%), Positives = 51/103 (49%), Gaps = 4/103 (3%)
Query: 3082 GTAIYLPGPDRCKMNPCLNGGTC-YPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGA 3140
G P + C NPC NGGTC T T Y C C PG+SG C+ D C SNPC NG
Sbjct: 95 GPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNPCANGG 153
Query: 3141 TCVDGFNTFRCLCLPSYVGALCEQDTETCDY--GWHKFQGQCY 3181
C+ ++ C C PS+ G C QD C G + G C+
Sbjct: 154 QCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCH 196
Score = 78.6 bits (192), Expect = 1e-13
Identities = 33/79 (41%), Positives = 45/79 (56%), Gaps = 2/79 (2%)
Query: 3093 CKMNPCLNGGTCYPTET--SYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
C +PC NGG C +E S+ C C G+ G CE+D +EC +PCR+GA+C + +R
Sbjct: 833 CAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYR 892
Query: 3151 CLCLPSYVGALCEQDTETC 3169
C C Y G CE D + C
Sbjct: 893 CHCQAGYSGRNCETDIDDC 911
Score = 77.8 bits (190), Expect = 2e-13
Identities = 32/79 (40%), Positives = 44/79 (55%), Gaps = 1/79 (1%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C +PC + G+C ++ C C PGY+G CE + +EC S PCR+G TC D N +
Sbjct: 568 DECDPDPC-HYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYL 626
Query: 3151 CLCLPSYVGALCEQDTETC 3169
C CL G CE + + C
Sbjct: 627 CFCLKGTTGPNCEINLDDC 645
Score = 76.3 bits (186), Expect = 5e-13
Identities = 33/83 (39%), Positives = 40/83 (48%), Gaps = 4/83 (4%)
Query: 3091 DRCKMNPCLNGGTC--YPTETSYVCTCVPGYSGDQCELDFDECH--SNPCRNGATCVDGF 3146
D C NPC G C P +CTC GY+G C D DEC +NPC + C++
Sbjct: 374 DACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTL 433
Query: 3147 NTFRCLCLPSYVGALCEQDTETC 3169
+F C CL Y G CE D C
Sbjct: 434 GSFECQCLQGYTGPRCEIDVNEC 456
Score = 75.9 bits (185), Expect = 6e-13
Identities = 33/90 (36%), Positives = 47/90 (52%), Gaps = 1/90 (1%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
+ C NPC++G C + Y C C PG+SG C+++ +EC SNPC NG TC D + +
Sbjct: 718 NECNSNPCVHGA-CRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYV 776
Query: 3151 CLCLPSYVGALCEQDTETCDYGWHKFQGQC 3180
C C + G C+ + C QG C
Sbjct: 777 CTCREGFSGPNCQTNINECASNPCLNQGTC 806
Score = 75.1 bits (183), Expect = 1e-12
Identities = 32/80 (40%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C NPC NGGTC + C C GY C + +EC+SNPC +GA C D N ++
Sbjct: 680 DECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGA-CRDSLNGYK 738
Query: 3151 CLCLPSYVGALCEQDTETCD 3170
C C P + G C+ + C+
Sbjct: 739 CDCDPGWSGTNCDINNNECE 758
Score = 73.6 bits (179), Expect = 3e-12
Identities = 30/80 (37%), Positives = 42/80 (52%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
+ C PCL+GGTC SY CTC GY+G C+ C S+PC+NG C +R
Sbjct: 1023 NECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYR 1082
Query: 3151 CLCLPSYVGALCEQDTETCD 3170
C C + G C+ + +C+
Sbjct: 1083 CECPSGWTGLYCDVPSVSCE 1102
Score = 72.4 bits (176), Expect = 7e-12
Identities = 32/74 (43%), Positives = 42/74 (56%), Gaps = 2/74 (2%)
Query: 3091 DRCKMNP--CLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNT 3148
D C++ P C NGGTC+ T Y C CV G++G+ C + D+C S C +GATC D +
Sbjct: 297 DECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVAS 356
Query: 3149 FRCLCLPSYVGALC 3162
F C C G LC
Sbjct: 357 FYCECPHGRTGLLC 370
Score = 72.4 bits (176), Expect = 7e-12
Identities = 28/72 (38%), Positives = 39/72 (54%)
Query: 3098 CLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPSY 3157
C +GG C ++ C C GY+G CE DEC +PC+NGATC D + C C+ Y
Sbjct: 1116 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGY 1175
Query: 3158 VGALCEQDTETC 3169
G C ++ + C
Sbjct: 1176 HGVNCSEEIDEC 1187
Score = 72.4 bits (176), Expect = 7e-12
Identities = 38/96 (39%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Query: 3088 PGPDRCKMNP-CLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPC--RNGATCVD 3144
P D +P C N GTC Y CTC PG+ G++CE D +EC SNPC R CV
Sbjct: 1227 PPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQ 1286
Query: 3145 GFNTFRCLCLPSYVGALCEQDTETCDYGWHKFQGQC 3180
N F C C + G CE C K G C
Sbjct: 1287 RVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTC 1322
Score = 69.7 bits (169), Expect = 5e-11
Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECH--SNPCRNGATCVDGFNT 3148
D C N C NGG C +Y C C P ++G C D DEC N C+NG TC +
Sbjct: 259 DDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGG 318
Query: 3149 FRCLCLPSYVGALCEQDTETC 3169
+ C+C+ + G C ++ + C
Sbjct: 319 YNCVCVNGWTGEDCSENIDDC 339
Score = 68.9 bits (167), Expect = 8e-11
Identities = 30/87 (34%), Positives = 41/87 (47%), Gaps = 10/87 (11%)
Query: 3093 CKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECH----------SNPCRNGATC 3142
C +PC NGG C+ T T Y C C G++G C++ C + C++G C
Sbjct: 1063 CDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLC 1122
Query: 3143 VDGFNTFRCLCLPSYVGALCEQDTETC 3169
VD NT C C Y G+ CE + C
Sbjct: 1123 VDAGNTHHCRCQAGYTGSYCEDLVDEC 1149
Score = 68.2 bits (165), Expect = 1e-10
Identities = 36/102 (35%), Positives = 49/102 (48%), Gaps = 7/102 (6%)
Query: 3090 PDRCKMNPCLNGGTCYPTE----TSYVCTCVPGYSGDQCELDFDE-CHSNPCRNGATC-V 3143
P+ C PC N GTC+ + Y C+C G+SG C D C +NPCRNG TC +
Sbjct: 60 PNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDL 119
Query: 3144 DGFNTFRCLCLPSYVGALCEQDTETCDYGWHKFQGQCYKYFA 3185
++C C P + G C+Q + C GQC + A
Sbjct: 120 LTLTEYKCRCPPGWSGKSCQQ-ADPCASNPCANGGQCLPFEA 160
Score = 68.2 bits (165), Expect = 1e-10
Identities = 31/74 (41%), Positives = 38/74 (51%), Gaps = 3/74 (4%)
Query: 3093 CKMNPCLNGGTCYP---TETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTF 3149
CK PC NGGTC T ++C C G+ G CE D C S C NG TC+ G +
Sbjct: 1311 CKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSP 1370
Query: 3150 RCLCLPSYVGALCE 3163
CLCL + G C+
Sbjct: 1371 TCLCLGPFTGPECQ 1384
Score = 66.6 bits (161), Expect = 4e-10
Identities = 32/84 (38%), Positives = 40/84 (47%), Gaps = 5/84 (5%)
Query: 3091 DRCKMNPCLNGGT--CYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNT 3148
+ C NPC GT C + C C G++G +CE + C PC+NG TC NT
Sbjct: 1269 NECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNT 1328
Query: 3149 ---FRCLCLPSYVGALCEQDTETC 3169
F C C + GA CE D TC
Sbjct: 1329 ARGFICKCPAGFEGATCENDARTC 1352
Score = 62.8 bits (151), Expect = 6e-09
Identities = 32/86 (37%), Positives = 40/86 (46%), Gaps = 7/86 (8%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATC----VDGF 3146
D C C +G TC+ S+ C C G +G C L+ D C SNPC G+ C V+G
Sbjct: 337 DDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLN-DACISNPCNEGSNCDTNPVNG- 394
Query: 3147 NTFRCLCLPSYVGALCEQDTETCDYG 3172
C C Y G C QD + C G
Sbjct: 395 -KAICTCPSGYTGPACSQDVDECSLG 419
Score = 52.0 bits (123), Expect = 1e-05
Identities = 31/85 (36%), Positives = 40/85 (47%), Gaps = 8/85 (9%)
Query: 3084 AIYLPGPDRCKM--NPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGAT 3141
A+ GP RC CLNGG C + C C + G +C+ D + C S PC+N T
Sbjct: 16 ALAARGP-RCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQ-DPNPCLSTPCKNAGT 73
Query: 3142 C--VD--GFNTFRCLCLPSYVGALC 3162
C VD G + C C + G LC
Sbjct: 74 CHVVDRRGVADYACSCALGFSGPLC 98
Score = 33.9 bits (76), Expect = 2.8
Identities = 15/33 (45%), Positives = 18/33 (54%), Gaps = 2/33 (6%)
Query: 3096 NPCLNGGTCYPTETS--YVCTCVPGYSGDQCEL 3126
NPC N GTC PT S Y C C ++G C +
Sbjct: 1395 NPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHI 1427
>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
sapiens]
Length = 2036
Score = 96.3 bits (238), Expect = 5e-19
Identities = 321/1458 (22%), Positives = 498/1458 (34%), Gaps = 182/1458 (12%)
Query: 368 SKEPQMVSDRTTPIIPLVDELPVIP------TEFPPVGNIVSFEQKATVQPQAITDSLAT 421
S E ++ D TT L +PV T P G+ + T +
Sbjct: 216 STETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRP 275
Query: 422 KLPTPTGSTKKPWDMDDYSPSA---------SGPLGKLDISEIKEEVLQSTTGVSHYATD 472
PT T + +P SPS+ S G ++ S ST + +D
Sbjct: 276 APPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESD 335
Query: 473 SWDGVVEDKQTQESVTQIEQIEVGPLVTSMEILK---------HIPSKEFPVTETPLVTA 523
+ G E+ T S T I P TS + + + FP + T +
Sbjct: 336 TTSGRGEESTTSHSSTT-HTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRS 394
Query: 524 RMILESKTEKKMVSTVSELVTTGHYGFTLGEEDDEDRTLTVGSDESTLIFDQIPEVITVS 583
S + + T+ L LGE ++ GS E+T + P T
Sbjct: 395 EESTASHSSQDATGTIV-LPARSTTSVLLGESTTSP--ISSGSMETTAL----PGSTTTP 447
Query: 584 KTSEDTIHTHLEDLESVSASTTVSPLIMPDNNGSSMDDWEERQTSGRITEEFLGKYLSTT 643
SE + H S +TT+SP + S + T F +TT
Sbjct: 448 GLSERSTTFHSSPR---SPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDS--TTT 502
Query: 644 PFPSQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRERTETLIPEMRTDTYTDEI 703
P S+H T P S D L+ +T PS ++ +H + + T
Sbjct: 503 PGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFG 562
Query: 704 QEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMTKSFDFP-TLITKLSAEPTE 762
QE T G T +F S+ + E+S + S P T ++ S+
Sbjct: 563 QESTTFHSNPGSTHTTLFPDSTTSSG------IVEASTRVHSSTGSPRTTLSPASSTSPG 616
Query: 763 VRDMEEDFTATPGTTKYDENITTVLLAHGTLSVEAATVSKWSWDEDNTTSKPLEST---- 818
++ F P +T + T + T VE +T S TT P ST
Sbjct: 617 LQGESTAFQTHPAST----HTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGH 672
Query: 819 ---------EPSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIPDSTQKQ-LEEV 868
P AS P + +T +G+ + S G+ E T +P ST L E
Sbjct: 673 SEKSTIFHSSPDASGTTPSSAHSTT--SGRGESTTSRISPGSTEITTLPGSTTTPGLSEA 730
Query: 869 TDEDIAAHGKFTIRFQPT--TSTGIAEKSTLRDS---TTEEKVPPITSTE---GQVYATM 920
+ ++ T P TS G+ E+ST S +T V P ++T + T+
Sbjct: 731 STTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTV 790
Query: 921 EGSALGEVEDVDLSKPVSTVPQFAHTSEVEG---LAFVSYSSTQEPTTYVDSSHTIPLSV 977
S+ G E +TV + T+ V G F S ++ T + + S T L
Sbjct: 791 YSSSRGSTE--------TTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGL-- 840
Query: 978 IPKTDWGVLVPSVPSEDEVLGEPSQDILVIDQTRLEATISPETMRT--TKITEGTTQEEF 1035
T+ P P+ + G P+ L E+T P + + TK++ +
Sbjct: 841 ---TEESTAFPGSPASTQT-GLPA--TLTTADLGEESTTFPSSSGSTGTKLSPARSTTSG 894
Query: 1036 PWKEQTAEKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPV 1095
E T + P+ + T P TP E + YT S R P +P
Sbjct: 895 LVGESTPSRLSPSSTETTTLPGSPTTP-SLSEKSTTFYT---------SPRSPDATLSPA 944
Query: 1096 GKIDHSVSYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLS 1155
VS + T H T P LS P + ++GS+ ++LS
Sbjct: 945 TTTSSGVS--EESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGST----EATLS 998
Query: 1156 PFSTHITQLMEETT--------TEKTSLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDI 1207
P ST + L +++T TE T L D + SGL E T S P+
Sbjct: 999 PGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASS 1058
Query: 1208 TTAFSSVDRLHTTSAFKPSSAITKKPPLIDREPGEETTSDMVIIGESTSHVPPTTLEDIV 1267
T+A + T ++ SS T PP P E +T T H P++
Sbjct: 1059 TSA-GLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVST---------TYHSRPSSTPTTH 1108
Query: 1268 AKETETDIDREYFTT---SSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHP-DIN 1323
+ T + R +T SSP AT PT + ++P ST+ +
Sbjct: 1109 FSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGS 1168
Query: 1324 VYIIEVRENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMAEI-LPEFPDIIEID 1382
+ E T S + S SEE+ H FP +
Sbjct: 1169 TTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMP 1228
Query: 1383 LYHSEENEEEEEECANATDVTTTP-SVQYINGKHLVTTVPKDPEAAE--------ARRGQ 1433
E +TD T +P S + TT P + E G
Sbjct: 1229 GVSQESTASHSS--PGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGL 1286
Query: 1434 FESVAPSQNFSDSSESDTHP--FVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSE 1491
E+ P + + S + P + E +T S +T + T T+
Sbjct: 1287 LEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTS 1346
Query: 1492 HFSGGEPDVFPTVPFHEEFESGTAKKGAESVTERDTEVGHQA--HEHTEPVSLFPEESSG 1549
H G P PT H S T + ES T + V S EES+
Sbjct: 1347 H---GSPSSTPTT--HFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTA 1401
Query: 1550 EIAIDQESQKIAFARATEVTFGEEVEKS--TSVTYTPTIVPSSASAYVSEEEAVTLIGNP 1607
+ +Q + F ++ + E ++ +S T+T + PS+ SA V E + +
Sbjct: 1402 YHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSY----HS 1457
Query: 1608 WPDDLLSTKESWVEATPRQVVELSGSSSIPITEG--------SGEAEEDEDTMF-----T 1654
P + +T T + E + S S P T G + E T F +
Sbjct: 1458 SPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGS 1517
Query: 1655 MVTDLSQRNTTDTL----ITLDTSRIITE--SFFEVPA---TTIYPVSEQPS--AKVVPT 1703
M T L+ TT L L TS ++ E +F+ P+ TT++P S S + T
Sbjct: 1518 METTLASTATTPGLSAKSTILYTSDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTT 1577
Query: 1704 KFVSETDTSEWISSTTVE 1721
S + TS +S+ ++E
Sbjct: 1578 FHTSPSFTSTIVSTESLE 1595
Score = 92.8 bits (229), Expect = 5e-18
Identities = 302/1407 (21%), Positives = 487/1407 (34%), Gaps = 181/1407 (12%)
Query: 1678 TESFFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWI--SSTTVEEK------------ 1723
T S F P+TT + S +PT +S T+ + STT
Sbjct: 280 TTSAFVEPSTTSHG-----SPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPES 334
Query: 1724 ---KRKEEEGTTGTASTFEVYSSTQRSDQLIL--PFELESPNVATSS----DSGTRKSFM 1774
+ EE TT +ST SS + ++ P S +T++ DS T
Sbjct: 335 DTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRS 394
Query: 1775 SLTTPTQSEREMTDSTPVFTETNTLENLGAQTTEH------------SSIHQPGVQEGLT 1822
+T + S ++ T + + + T LG TT S PG+ E T
Sbjct: 395 EESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERST 454
Query: 1823 TL---PRSPASVFMEQGSGEAAADPETTTVSSFSLNVEYAIQAEKEVAGTLSPHVETTFS 1879
T PRSPA+ + + E+TT S + + LS H T+ S
Sbjct: 455 TFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHS 514
Query: 1880 ----TEPTGLVLSTVMDRVVAENITQTSREIVISERLGEPN-----YGAEIRGF------ 1924
T+ T L ST E+ T S L + +G E F
Sbjct: 515 SPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGS 574
Query: 1925 --STGFPLEEDFSGDFREYSTVSHPIAKEETVMMEGSGDA-AFRDTQTSPSTVPTSVHIS 1981
+T FP SG + V T + S + + T+ T P S H +
Sbjct: 575 THTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTT 634
Query: 1982 HISDSEGPSSTMVSTS------AFPWEEFTSSAEGSGEQLVTVSSSVVPVLPSAVQKFSG 2035
S + ST+ + P F +S+ SG + S++ P A
Sbjct: 635 PSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGH---SEKSTIFHSSPDASGTTPS 691
Query: 2036 TASSIIDEGLGEVGTVNEIDRRSTILPTAEVEGTKAPVEKEEVKVSGTVSTNFPQT-IEP 2094
+A S G GE T + I ST + T + G+ E + S P T + P
Sbjct: 692 SAHSTTS-GRGE-STTSRISPGSTEITT--LPGSTTTPGLSEASTTFYSSPRSPTTTLSP 747
Query: 2095 AKLWS----------RQEVNPVRQEIESETTSEEQIQEEKSFESPQNSPATEQTIFDSQT 2144
A + S R + + +T+ + EE + + +TE T+F T
Sbjct: 748 ASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHST 807
Query: 2145 FTET--ELKTTDYSVLTTKKT--YSDDKE---MKEEDTSLVNMSTPDPDANGLESYTTLP 2197
T E TT +S + T +++D + EE T+ +P GL + T
Sbjct: 808 TTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPG--SPASTQTGLPATLTTA 865
Query: 2198 EATEKSHFFLATALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESDTELLFSGLG 2257
+ E+S F +++ T + + T S + E + P + P+ E+ T
Sbjct: 866 DLGEESTTFPSSSGSTGTKLSPARSTTSGLVGEST----PSRLSPSSTETTTL------- 914
Query: 2258 SGEEVLPTLPTESVNF-TEVEQINNTLYPHTSQVESTSSDKIEDFNRMENVAKEVGPLVS 2316
G P+L +S F T + TL P T+ TSS E E+ P +
Sbjct: 915 PGSPTTPSLSEKSTTFYTSPRSPDATLSPATT----TSSGVSE-----ESSTSHSQPGST 965
Query: 2317 QTDIFEGSGSVTSTTLIEILSDTGAEGPTVAPL-PFSTDIGHPQNQTVRWAE-----EIQ 2370
T F S + TS E + ++G T A L P ST Q+ + E
Sbjct: 966 HTTAFPDS-TTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETT 1024
Query: 2371 TSRPQTIT----EQDSNKNSSTAEINETTTSSTDFLARAYGFEMAKEFVTSAPKPSDLYY 2426
TIT E + +SST ++ T T ++ A G + S P SD
Sbjct: 1025 LLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSA---GLQEESTTFQSWPSSSDTTP 1081
Query: 2427 EPSGEGSGEVDIVDSFHT--SATTQATRQESSTTFVSDGSLEKHPEVPSAKAVTADG-FP 2483
P G + V++ ++H+ S+T SSTT G E+ V S+ T FP
Sbjct: 1082 SPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTL---GRSEESTTVHSSPGATGTALFP 1138
Query: 2484 TVSVMLPLHSEQNKSSPDPTSTLSNTVSYERSTDGSFQDRFREFEDSTLKPNRKKPTENI 2543
T S L E +SP + + T +T ++ F S P+ +
Sbjct: 1139 TRSATSVLVGEPT-TSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPAST 1197
Query: 2544 IIDLDKEDKDLILTITESTILEILPELT-----SDKNTIIDIDHTKPVYEDILGMQTDID 2598
E+ + ST P T S ++T H+ P D +
Sbjct: 1198 TSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQEST---ASHSSPGSTDTT-LSPGST 1253
Query: 2599 TEVPSEPHDSNDESNDDSTQVQEIYEAAVNLSLTEETFEGSADVLASYTQATHDESMTYE 2658
T P + S+ ST+ + + L E + + + +T + S T +
Sbjct: 1254 TASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQ 1313
Query: 2659 DRSQLDHMGFHFTTGIPAPSTETELDVLLPT-----------------ATSLPIPRKSAT 2701
S +PAP T T V L T +T+L +S T
Sbjct: 1314 GESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTT 1373
Query: 2702 V----IPEIEGIKAEAKALDDMFESSTLSDGQAIADQSEIIP----TLGQFERTQEEYED 2753
V + + E ST + Q+ P G+ E ++ +
Sbjct: 1374 VHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSS 1433
Query: 2754 KKHAGPSFQPEFSSGAEEALVDHTPYLSIATTHLMDQSVTEVPDVMEGSNPPYYTDTTLA 2813
H S S+ EE H+ SIATTH + S T E S + + T
Sbjct: 1434 TTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTS--GRSEESTASHSSPDTNG 1491
Query: 2814 VSTF-AKLSSQTPSSPLTIYSGSEASGHTEIPQPSALPGIDVGSSVMSPQDSFKE---IH 2869
++ A ++ + T + S S T + + PG+ S+++ D E +
Sbjct: 1492 ITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYTSDLVGEPTTFY 1551
Query: 2870 VNIEATFK---PSSEEYLHITEPPSLSPDTKLEPSEDDGKPELLEEMEASPTELIAVEGT 2926
++ T+ P+S +TE + + S L +P +L A G
Sbjct: 1552 ISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAPETPEKLNATLGM 1611
Query: 2927 EILQDFQNKTD--GQVSGEAIKMFPTI 2951
+ ++N T+ S + + F T+
Sbjct: 1612 TVKVTYRNFTEKMNDASSQEYQNFSTL 1638
Score = 92.4 bits (228), Expect = 7e-18
Identities = 378/1746 (21%), Positives = 584/1746 (33%), Gaps = 270/1746 (15%)
Query: 642 TTPFP-SQHRTEIELFPYSGDKILVEGISTVIYPSLQTEMTHRRERTETLIPEMRTDTYT 700
+TP P S E P S K + ST Y S ++ T T +P T +
Sbjct: 95 STPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDT-------THLPASMTSSGV 147
Query: 701 DEIQEEITKSPFMGKTEEEVFSGMKLSTSLSEPIHVTESSVEMTKSFDFPTLITKLSAEP 760
E E T G T F G LS+ + SS T + P T S P
Sbjct: 148 SE--ESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGP 205
Query: 761 TEVRDMEEDFTATPG---TTKYDENITTVLLAHGTLSVEAATVSKWSW-DEDNTTSKPLE 816
F + PG TT +N T L ++ V ++T S + +T++ E
Sbjct: 206 EYTT-----FHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGE 260
Query: 817 STE----PSASSKLPPALLTTVGMNGKDKDIPSFTEDGADEFTLIP-------DSTQKQL 865
ST PS+ P TT PS T G+ + IP +T +
Sbjct: 261 STTFHSWPSSKDTRPAPPTTTSAFVE-----PSTTSHGSP--SSIPTTHISARSTTSGLV 313
Query: 866 EEVTDEDIAAHGKFTIRF-QPTTSTGIAEKSTLRDSTTEEKVPPITSTEGQVYATMEGSA 924
EE T + T+ F + T++G E+ST S+T + ST SA
Sbjct: 314 EESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTT---------SA 364
Query: 925 LGEVEDVDLSKPVSTVP-QFAHTSEVEGLAFVSYSSTQEPTTYVDSSHTIPLSVIPKTDW 983
L E S P ST F +S G + S +S D++ TI L
Sbjct: 365 LVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQ----DATGTIVL-------- 412
Query: 984 GVLVPSVPSEDEVLGEPSQDILVIDQTRLEATISPETMRTTKITE-GTTQEEFPWKEQTA 1042
P+ + +LGE + I +E T P + T ++E TT P T
Sbjct: 413 ----PARSTTSVLLGESTTS--PISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATT 466
Query: 1043 EKPVPALSSTAWTPKEAVTPLDEQEGDGSAYTVSEDELLTGSERVPVLETTPVGKIDHSV 1102
P SS +E+ T + GS +T + P TTP G HS
Sbjct: 467 LSPASTTSSGV--SEESTT---SRSRPGSTHTTA----------FPDSTTTP-GLSRHST 510
Query: 1103 SYPPGAVTEHKVKTDEVVTLTPRIGPKVSLSPGPEQKYETEGSSTTGFTSSLSPFSTHIT 1162
T H TL P + + GP Q+ T SS+ ++LSP ST
Sbjct: 511 -------TSHSSPGSTDTTLLPAS----TTTSGPSQESTTSHSSSGSTDTALSPGSTTAL 559
Query: 1163 QLMEETT--------TEKTSLEDIDLGSGLFEKPKATELIEFSTIKVTVPSDITTAFSSV 1214
+E+T T T D SG+ E +T + + T S ++ +
Sbjct: 560 SFGQESTTFHSNPGSTHTTLFPDSTTSSGIVE--ASTRVHSSTGSPRTTLSPASSTSPGL 617
Query: 1215 DRLHTTSAFKPSSA-ITKKPPLIDREPGEETTSDMVIIGES-TSHVPPTTLEDIVAKET- 1271
T P+S T PP P EE+T+ G + T+H P ++ ++++
Sbjct: 618 QGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKST 677
Query: 1272 --ETDIDREYFTTSSPPATQPTRPPTVEDKEAFGPQALSTPQPPASTKFHPDINVYIIEV 1329
+ D T SS +T R + + + G ++T +T + +
Sbjct: 678 IFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSS 737
Query: 1330 RENKTGRMSDLSVIGHPIDSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEEN 1389
+ T +S S+ + ES + H ++ P + SEE+
Sbjct: 738 PRSPTTTLSPASMTSLGVGEESTTSR---SQPGSTHSTVSPASTTTPGL-------SEES 787
Query: 1390 EEEEEECANATDVTTTPSVQYINGKHLVTTVPKDPEAAEARRGQFESVAPSQNFSDSSES 1449
+T+ T P H TT E F S S + + +E
Sbjct: 788 TTVYSSSRGSTETTVFP--------HSTTTSVHGEEPT-----TFHSRPASTHTTLFTED 834
Query: 1450 DTHPFVIAKTELSTAVQPNESTETTESLEVTWKPETYPETSEHFSGGEPDVFPTVPFHEE 1509
T TE STA P T L T E S F +
Sbjct: 835 ST---TSGLTEESTAF-PGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARS 890
Query: 1510 FESG-----TAKKGAESVTERDTEVGHQAHEHTEPVSLFPEESSGEIAIDQESQKIAFAR 1564
SG T + + S TE T G P + E S S +
Sbjct: 891 TTSGLVGESTPSRLSPSSTETTTLPG-------SPTTPSLSEKSTTFYTSPRSPDATLSP 943
Query: 1565 ATEVTFGEEVEKSTS-----VTYTPTIVPSSASAYVSEEEAVTLIGNPWPDDLLSTKESW 1619
AT + G E STS T+T S+ ++ +S+E + + LS +
Sbjct: 944 ATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTT 1003
Query: 1620 VEATPRQVVELSGS------SSIP-------ITEGSGEAEEDEDTMFTMVTDLSQRNT-- 1664
+ +Q S + +P + E S ++ T +T S +
Sbjct: 1004 ASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGL 1063
Query: 1665 TDTLITLDTSRIITESFFEVPATTIYPVSEQPSAKVVPTKFVSETDTSEWISSTTV---- 1720
+ T + +++ P TT PV + P S T T+ + +S+T
Sbjct: 1064 QEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRP----SSTPTTHFSASSTTLGRS 1119
Query: 1721 -EEKKRKEEEGTTGTASTFEVYSSTQRSDQLILPFELESPNVATSSDSGTRKSFM--SLT 1777
E G TGTA F S+T +L E P + S T + + S T
Sbjct: 1120 EESTTVHSSPGATGTA-LFPTRSATS-----VLVGE---PTTSPISSGSTETTALPGSTT 1170
Query: 1778 TPTQSEREMT-DSTPVFTETNTLENLGAQTTEHSSIHQPGVQEGLTTLPRSPASVFMEQG 1836
T SE+ T S+P +T T +S GV E TT P S
Sbjct: 1171 TAGLSEKSTTFYSSPRSPDT---------TLSPASTTSSGVSEESTTSHSRPGSTHTTAF 1221
Query: 1837 SGEA---AADPETTTVSSFSLNVEYAIQAEKEVAGTLSPHVETTFSTEPTGLVLSTVMDR 1893
G E+T S + + + A +L P TTF + P + + D
Sbjct: 1222 PGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPE-STTFHSSPGSTETTLLPDN 1280
Query: 1894 VVAENITQTSREIVISERLGEPNYGAEIRGFSTGFPLEEDFSGDFREYSTVSHPIAKEET 1953
A + + S + S G P+ G +T + S F+ + + ++T
Sbjct: 1281 TTASGLLEASTPVHSS--TGSPHTTLSPAGSTT----RQGESTTFQSWP------SSKDT 1328
Query: 1954 VMMEGSGDAAFRDTQTSPSTVPTSVHISHISDSEGPSSTMVSTSAFPWEEFTSSAEGSGE 2013
+ + +AF + T+ P+S +H S S S+ G E
Sbjct: 1329 MPAPPTTTSAFVELSTTSHGSPSSTPTTHFSAS-------------------STTLGRSE 1369
Query: 2014 QLVTVSSSVV--PVLPSAVQKFSGTASSIIDEGL---GEVGTVNEIDRRSTILPTAEVEG 2068
+ TV SS V PS + T S +++E G+ + + + E
Sbjct: 1370 ESTTVHSSPVATATTPSPAR---STTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEE 1426
Query: 2069 TKAPVEKEEVKVSGTVSTNFPQTIEPAKLWSRQEVNPVRQEIESETTSEEQIQEEKSFES 2128
++ +S ST EP S ES TTS + S S
Sbjct: 1427 SRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSS 1486
Query: 2129 PQNSPATEQTIFDSQTFTETELKTTDYSVLTTKKTYSDDKEMKEEDTSLVNMSTPDPDAN 2188
P + T TT + + Y M E T +TP A
Sbjct: 1487 PDTNGITPLPAH----------FTTSGRIAESTTFYISPGSM--ETTLASTATTPGLSAK 1534
Query: 2189 GLESYTTLPEATEKSHFFLATALVTESIPAEHVVTDSPIKKEESTKHFPKGMRPTIQESD 2248
YT+ + + + T PA + S + +E +T H TI ++
Sbjct: 1535 STILYTSDLVGEPTTFYISPSPTYTTLFPASS--STSGLTEESTTFHTSPSFTSTIVSTE 1592
Query: 2249 TELLFSGLGSGEEVLPTLPTESVNFTEVEQINNTLYPHTSQVESTSSDKIEDF-----NR 2303
S E + P P E +N T + T T ++ SS + ++F NR
Sbjct: 1593 ---------SLETLAPETP-EKLNATLGMTVKVTYRNFTEKMNDASSQEYQNFSTLFKNR 1642
Query: 2304 MENVAK 2309
M+ V K
Sbjct: 1643 MDVVLK 1648
Score = 63.5 bits (153), Expect = 3e-09
Identities = 228/1046 (21%), Positives = 351/1046 (33%), Gaps = 154/1046 (14%)
Query: 2177 LVNMSTPDPDANGLESYTTLPEAT------EKSHFFLATALVTESIPAEHVVTDSPIKKE 2230
LV STP P ++G T LP +T EKS F ++ ++ +T S + +E
Sbjct: 91 LVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEE 150
Query: 2231 ESTKHFPKGMRPTI------------QESDTELLFSG-----LGSGEEVLPTLPTESVNF 2273
+T H G T QES G L G +L E F
Sbjct: 151 STTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTF 210
Query: 2274 ------TEVEQI-----------------NNTLYPHTSQVESTSSDKIEDFNRMEN--VA 2308
TE + ++T PHT+ + S+ + + + +
Sbjct: 211 HSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSS 270
Query: 2309 KEVGP--------LVSQTDIFEGSGSVTSTTLIEILSDTGA---EGPTVAPLPFSTDIGH 2357
K+ P V + GS S TT I S T E T P ST H
Sbjct: 271 KDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMH 330
Query: 2358 -PQNQTVRWAEEIQTSRPQTITEQDSNKNSSTAEINETTTSSTDFLARAYGFEMAKEFVT 2416
P++ T E T+ + T S+ S+T+ + E TS T
Sbjct: 331 FPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTT 390
Query: 2417 SAPKPSDLYYEPSGEGSGEVDIVDSFHTSATTQATRQESSTTFVSDGSLEKHPEVPSAKA 2476
S S + +G + + +TT ES+T+ +S GS+E +P +
Sbjct: 391 SGRSEESTASHSSQDATGTIVLP----ARSTTSVLLGESTTSPISSGSMET-TALPGS-- 443
Query: 2477 VTADGFPTVSVMLPLHSEQNKSSPDPTSTLSNTVSYERSTDGSF--QDRFREFEDSTLKP 2534
T G S ++ P ST S+ VS E +T S F DST P
Sbjct: 444 TTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTP 503
Query: 2535 NRKKPTENIIIDLDKEDKDLI--LTITESTILEILPELTSDKNTIIDIDHTKPVYEDILG 2592
+ + D L+ T T E +S +T + P L
Sbjct: 504 GLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALS---PGSTTALS 560
Query: 2593 MQTDIDTEVPSEPHDSNDESNDDSTQVQEIYEAAVNL--------------SLTEETFEG 2638
+ T S P ++ DST I EA+ + S T +G
Sbjct: 561 FGQE-STTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQG 619
Query: 2639 SADVLASYTQATH-------------DESMTYEDRSQLDHMGFHFTTGIPAPSTET---- 2681
+ ++ +TH +ES TY RS G TT PA ST +
Sbjct: 620 ESTAFQTHPASTHTTPSPPSTATAPVEESTTYH-RSP----GSTPTTHFPASSTTSGHSE 674
Query: 2682 ---------ELDVLLPTATSLPIPRKSATVIPEIEGIKAEAKALDDMFESSTLSDGQAIA 2732
+ P++ + + I E L + LS+
Sbjct: 675 KSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF 734
Query: 2733 DQSEIIPT--LGQFERTQEEYEDKKHAGPSFQPEFSSGAEEALVDHTPYLSIATTHLMDQ 2790
S PT L T ++ S QP + TP LS +T +
Sbjct: 735 YSSPRSPTTTLSPASMTSLGVGEESTTSRS-QPGSTHSTVSPASTTTPGLSEESTTVYSS 793
Query: 2791 SVTEVPDVMEGSNPPYYTDTTLAVSTFAKLSSQTPSSPLTIYS-GSEASGHTEIPQPSAL 2849
S E + P+ T T++ S+ S+ T+++ S SG TE + +A
Sbjct: 794 SRGST----ETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTE--ESTAF 847
Query: 2850 PGIDVGSSVMSPQDSFKEIHVNIEATFKPSSEEYLHITEPPSLSPDTKLEPSEDDGKPEL 2909
PG + P + + E+T PSS S S TKL P+ +
Sbjct: 848 PGSPASTQTGLPA-TLTTADLGEESTTFPSS----------SGSTGTKLSPARSTTSGLV 896
Query: 2910 LEEMEASPTELIAVEGTEILQDFQNKTDGQVSGEAIKMFPTIKTPEA--GTVITTADEIE 2967
E++P+ L + TE + T +S ++ + + ++P+A TT+ +
Sbjct: 897 ---GESTPSRL-SPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVS 952
Query: 2968 LEGATQWPHSTSASATYGVEAGVVPWLS--PQTSERPTLSSSPEINPETQAALIRGQDST 3025
E +T S T ++ LS P TS S+ ++P + A GQ ST
Sbjct: 953 EESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQST 1012
Query: 3026 IAASEQQVAARILDSNDQATVNPVEFNTEVATPPFSLLET-SNETDFLIGINEESVEGTA 3084
S L +D T VE +T + SL T + + G+ EES
Sbjct: 1013 TFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEES----T 1068
Query: 3085 IYLPGPDRCKMNPCLNGGTCYPTETS 3110
+ P P G T P E S
Sbjct: 1069 TFQSWPSSSDTTPSPPGTTAAPVEVS 1094
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 95.1 bits (235), Expect = 1e-18
Identities = 40/88 (45%), Positives = 50/88 (56%), Gaps = 7/88 (7%)
Query: 3093 CKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRCL 3152
C NPC NGG+C+ + + C C G+SG C LD DEC SNPC G TCVD + F C+
Sbjct: 351 CTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECI 410
Query: 3153 CLPSYVGALCEQDTETCDYGWHKFQGQC 3180
C +VGA C+ D C +GQC
Sbjct: 411 CPEQWVGATCQLDVNDC-------RGQC 431
Score = 82.8 bits (203), Expect = 5e-15
Identities = 33/77 (42%), Positives = 44/77 (57%)
Query: 3093 CKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRCL 3152
C NPC+NGGTC + S+ C C G+ G C + ++C+ PC NG CVDG N FRC
Sbjct: 717 CLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCE 776
Query: 3153 CLPSYVGALCEQDTETC 3169
C P + G C + + C
Sbjct: 777 CAPGFAGPDCRINIDEC 793
Score = 82.8 bits (203), Expect = 5e-15
Identities = 32/72 (44%), Positives = 41/72 (56%)
Query: 3093 CKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRCL 3152
C PC NGG C + C C PG++G C ++ DEC S+PC GATCVD N +RC
Sbjct: 755 CNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCS 814
Query: 3153 CLPSYVGALCEQ 3164
C P G C++
Sbjct: 815 CPPGRAGPRCQE 826
Score = 77.4 bits (189), Expect = 2e-13
Identities = 33/84 (39%), Positives = 44/84 (52%)
Query: 3098 CLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPSY 3157
C +GGTC Y C C G+ G CEL+ DEC S+PC +G C D + F C C +
Sbjct: 431 CQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGF 490
Query: 3158 VGALCEQDTETCDYGWHKFQGQCY 3181
G LCE D + C+ + +CY
Sbjct: 491 SGPLCEVDVDLCEPSPCRNGARCY 514
Score = 72.4 bits (176), Expect = 7e-12
Identities = 31/82 (37%), Positives = 40/82 (48%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C +PC +GG C + C C G+SG CE+D D C +PCRNGA C + +
Sbjct: 462 DECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYY 521
Query: 3151 CLCLPSYVGALCEQDTETCDYG 3172
C C + G C E C G
Sbjct: 522 CACPDDFGGKNCSVPREPCPGG 543
Score = 72.4 bits (176), Expect = 7e-12
Identities = 30/80 (37%), Positives = 42/80 (52%), Gaps = 1/80 (1%)
Query: 3092 RCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDE-CHSNPCRNGATCVDGFNTFR 3150
+C C NGGTCY + ++ C C PG+ G C + + C NPC NG TCV +F
Sbjct: 677 QCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFS 736
Query: 3151 CLCLPSYVGALCEQDTETCD 3170
C+C + G C +T C+
Sbjct: 737 CICRDGWEGRTCTHNTNDCN 756
Score = 68.2 bits (165), Expect = 1e-10
Identities = 27/73 (36%), Positives = 37/73 (50%)
Query: 3090 PDRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTF 3149
P+ C +PC + G CY + C C G+ G C +C + C NG TC D +TF
Sbjct: 637 PNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTF 696
Query: 3150 RCLCLPSYVGALC 3162
RC C P + G+ C
Sbjct: 697 RCACPPGWKGSTC 709
Score = 67.4 bits (163), Expect = 2e-10
Identities = 30/91 (32%), Positives = 41/91 (45%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C PC NGGTC ++ C C G+ G+ C+ + ++C +PC + C D N F
Sbjct: 600 DDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFY 659
Query: 3151 CLCLPSYVGALCEQDTETCDYGWHKFQGQCY 3181
C C + G C CD G CY
Sbjct: 660 CACDDGWKGKTCHSREFQCDAYTCSNGGTCY 690
Score = 67.0 bits (162), Expect = 3e-10
Identities = 26/72 (36%), Positives = 39/72 (54%)
Query: 3110 SYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPSYVGALCEQDTETC 3169
++ C C G++G C + D+C PCRNG TC+D + FRC C + G LC+ + C
Sbjct: 581 NFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDC 640
Query: 3170 DYGWHKFQGQCY 3181
+G+CY
Sbjct: 641 LPDPCHSRGRCY 652
Score = 51.6 bits (122), Expect = 1e-05
Identities = 30/130 (23%), Positives = 45/130 (34%), Gaps = 34/130 (26%)
Query: 3074 GINEESVEGTAIYLP----GP------DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQ 3123
G+ E+ +G + P GP D C+ +PC NG CY E Y C C + G
Sbjct: 473 GLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKN 532
Query: 3124 CELDFDECHSNPCR------------------------NGATCVDGFNTFRCLCLPSYVG 3159
C + + C CR +G F C+C + G
Sbjct: 533 CSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTG 592
Query: 3160 ALCEQDTETC 3169
C ++ + C
Sbjct: 593 TYCHENIDDC 602
Score = 51.2 bits (121), Expect = 2e-05
Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 7/95 (7%)
Query: 3091 DRCKMNP-CLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHS-NPCRNGATCVDGF-N 3147
D C P C++G P + C C + G C+ D + C S +PC NG TC++ +
Sbjct: 274 DECVPYPGCVHGSCVEPWQ----CNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPD 329
Query: 3148 TFRCLCLPSYVGALCEQDTETCDYGWHKFQGQCYK 3182
+RC C Y G CE+ C G C++
Sbjct: 330 QYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHE 364
Score = 46.2 bits (108), Expect = 5e-04
Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 5/67 (7%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCE--LDFD-ECHS--NPCRNGATCVDG 3145
D C+ +PC G TC Y C+C PG +G +C+ + F C S P +G++ V+
Sbjct: 791 DECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVED 850
Query: 3146 FNTFRCL 3152
N+ RCL
Sbjct: 851 CNSCRCL 857
Score = 35.8 bits (81), Expect = 0.74
Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 11/71 (15%)
Query: 3099 LNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPSYV 3158
L+GG P E C C G+ G C DEC P +CV+ ++C C ++
Sbjct: 252 LHGGCTVPGE----CRCSYGWQGRFC----DECVPYPGCVHGSCVE---PWQCNCETNWG 300
Query: 3159 GALCEQDTETC 3169
G LC++D C
Sbjct: 301 GLLCDKDLNYC 311
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 94.7 bits (234), Expect = 1e-18
Identities = 36/79 (45%), Positives = 49/79 (62%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C+ +PC+NGG C + CTC G+SG C+LD DEC S PCRNGA CVD + +
Sbjct: 471 DECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYE 530
Query: 3151 CLCLPSYVGALCEQDTETC 3169
C C + G LC+++ + C
Sbjct: 531 CRCAEGFEGTLCDRNVDDC 549
Score = 94.4 bits (233), Expect = 2e-18
Identities = 39/79 (49%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C NPC GTC S+ CTC PGY G CE D +C + C NG TCVDG N+F
Sbjct: 889 DECLSNPC-GPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFS 947
Query: 3151 CLCLPSYVGALCEQDTETC 3169
CLC P Y GA C+ + + C
Sbjct: 948 CLCRPGYTGAHCQHEADPC 966
Score = 93.2 bits (230), Expect = 4e-18
Identities = 35/78 (44%), Positives = 49/78 (62%), Gaps = 1/78 (1%)
Query: 3093 CKMNPCLNGGTCYPT-ETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRC 3151
C +PC NGGTC + + +Y C C+PG+ G CE++ D+C + C NG TCVDG NT+ C
Sbjct: 201 CAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNC 260
Query: 3152 LCLPSYVGALCEQDTETC 3169
C P + G C +D + C
Sbjct: 261 QCPPEWTGQFCTEDVDEC 278
Score = 91.3 bits (225), Expect = 1e-17
Identities = 37/82 (45%), Positives = 49/82 (59%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C PC +GGTC Y+C C+PGY+GD CE D DEC S PC++G +C+D +
Sbjct: 1086 DPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYL 1145
Query: 3151 CLCLPSYVGALCEQDTETCDYG 3172
C C P +G LCE + + C G
Sbjct: 1146 CSCPPGTLGVLCEINEDDCGPG 1167
Score = 90.1 bits (222), Expect = 3e-17
Identities = 39/77 (50%), Positives = 47/77 (61%), Gaps = 1/77 (1%)
Query: 3093 CKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRCL 3152
C NPCLNGG+C S+ C+C+PG++G +C D DEC SNPC G TC D +F C
Sbjct: 853 CDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPG-TCTDHVASFTCT 911
Query: 3153 CLPSYVGALCEQDTETC 3169
C P Y G CEQD C
Sbjct: 912 CPPGYGGFHCEQDLPDC 928
Score = 88.2 bits (217), Expect = 1e-16
Identities = 36/81 (44%), Positives = 49/81 (60%), Gaps = 2/81 (2%)
Query: 3091 DRCKM--NPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNT 3148
D C + NPC + G C T+ S++C C GY+G +CE D +EC S PCRN ATC+D
Sbjct: 393 DECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQ 452
Query: 3149 FRCLCLPSYVGALCEQDTETC 3169
F C+C+ + G CE D + C
Sbjct: 453 FTCICMAGFTGTYCEVDIDEC 473
Score = 81.6 bits (200), Expect = 1e-14
Identities = 31/79 (39%), Positives = 42/79 (53%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
+ C PC N TC + C C+ G++G CE+D DEC S+PC NG C D N F
Sbjct: 433 NECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFS 492
Query: 3151 CLCLPSYVGALCEQDTETC 3169
C C + G+ C+ D + C
Sbjct: 493 CTCPSGFSGSTCQLDVDEC 511
Score = 81.3 bits (199), Expect = 2e-14
Identities = 33/90 (36%), Positives = 43/90 (47%), Gaps = 1/90 (1%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C PC NG C Y C C G+ G C+ + D+C +PC +G CVDG +F
Sbjct: 509 DECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHG-RCVDGIASFS 567
Query: 3151 CLCLPSYVGALCEQDTETCDYGWHKFQGQC 3180
C C P Y G CE + C + G+C
Sbjct: 568 CACAPGYTGTRCESQVDECRSQPCRHGGKC 597
Score = 80.9 bits (198), Expect = 2e-14
Identities = 32/79 (40%), Positives = 43/79 (54%), Gaps = 1/79 (1%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C+ PC +GG C Y+C C G +G CE++ D+C SNPC G C DG N +
Sbjct: 584 DECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFG-VCRDGINRYD 642
Query: 3151 CLCLPSYVGALCEQDTETC 3169
C+C P + G LC + C
Sbjct: 643 CVCQPGFTGPLCNVEINEC 661
Score = 80.1 bits (196), Expect = 3e-14
Identities = 31/73 (42%), Positives = 41/73 (56%)
Query: 3097 PCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPS 3156
PC G C S+ CTC GY+G C+ D ++C NPC NG +C DG +F C CLP
Sbjct: 819 PCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPG 878
Query: 3157 YVGALCEQDTETC 3169
+ G C +D + C
Sbjct: 879 FAGPRCARDVDEC 891
Score = 79.0 bits (193), Expect = 8e-14
Identities = 34/82 (41%), Positives = 44/82 (53%), Gaps = 2/82 (2%)
Query: 3090 PDRCKMNPCLNGGTC-YPTETSYVCTCVPGYSGDQCELDFDECH-SNPCRNGATCVDGFN 3147
PD C +PC +G C + ++C+C PGY G C D DEC PCR+G TC++
Sbjct: 120 PDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPG 179
Query: 3148 TFRCLCLPSYVGALCEQDTETC 3169
+FRC C Y G LCE C
Sbjct: 180 SFRCQCPAGYTGPLCENPAVPC 201
Score = 78.2 bits (191), Expect = 1e-13
Identities = 34/79 (43%), Positives = 43/79 (54%), Gaps = 1/79 (1%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C NPC G C Y C C PG++G C ++ +EC S+PC G +CVDG N FR
Sbjct: 622 DDCASNPC-TFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFR 680
Query: 3151 CLCLPSYVGALCEQDTETC 3169
CLC P + LC + C
Sbjct: 681 CLCPPGSLPPLCLPPSHPC 699
Score = 78.2 bits (191), Expect = 1e-13
Identities = 35/89 (39%), Positives = 43/89 (48%), Gaps = 7/89 (7%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNP-------CRNGATCV 3143
D C PC +GG+C Y+C+C PG G CE++ D+C P C + TCV
Sbjct: 1124 DECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCV 1183
Query: 3144 DGFNTFRCLCLPSYVGALCEQDTETCDYG 3172
D FRC C P Y G CE D C G
Sbjct: 1184 DLVGGFRCTCPPGYTGLRCEADINECRSG 1212
Score = 77.4 bits (189), Expect = 2e-13
Identities = 36/97 (37%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 3090 PDRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTF 3149
PD C + C NGGTC S+ C C PGY+G C+ + D C S PC +G C F
Sbjct: 926 PD-CSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGF 984
Query: 3150 RCLCLPSYVGALCEQDTETCDYGWHKFQGQCYKYFAH 3186
RC CL S+ G C+ + C + G+C + A+
Sbjct: 985 RCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAY 1021
Score = 75.9 bits (185), Expect = 6e-13
Identities = 35/81 (43%), Positives = 45/81 (55%), Gaps = 2/81 (2%)
Query: 3091 DRCKMN-PCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATC-VDGFNT 3148
D C++ PC +GGTC T S+ C C GY+G CE C +PCRNG TC G T
Sbjct: 160 DECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLT 219
Query: 3149 FRCLCLPSYVGALCEQDTETC 3169
+ C CLP + G CE + + C
Sbjct: 220 YDCACLPGFEGQNCEVNVDDC 240
Score = 74.3 bits (181), Expect = 2e-12
Identities = 31/79 (39%), Positives = 42/79 (53%), Gaps = 1/79 (1%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C +PC + G C S+ C C PGY+G +CE DEC S PCR+G C+D + +
Sbjct: 547 DDCSPDPC-HHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYL 605
Query: 3151 CLCLPSYVGALCEQDTETC 3169
C C G CE + + C
Sbjct: 606 CRCPSGTTGVNCEVNIDDC 624
Score = 72.4 bits (176), Expect = 7e-12
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNP--CRNGATCVDGFNT 3148
D C + CLNGGTC +Y C C P ++G C D DEC P C NG TC +
Sbjct: 238 DDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGG 297
Query: 3149 FRCLCLPSYVGALCEQDTETC 3169
C+C+ + G C Q+ + C
Sbjct: 298 HSCVCVNGWTGESCSQNIDDC 318
Score = 71.6 bits (174), Expect = 1e-11
Identities = 31/77 (40%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Query: 3091 DRCKMNP--CLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNT 3148
D C++ P C NGGTC+ T + C CV G++G+ C + D+C + C +GATC D +
Sbjct: 276 DECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVAS 335
Query: 3149 FRCLCLPSYVGALCEQD 3165
F C C G LC D
Sbjct: 336 FYCACPMGKTGLLCHLD 352
Score = 71.6 bits (174), Expect = 1e-11
Identities = 35/94 (37%), Positives = 44/94 (46%), Gaps = 4/94 (4%)
Query: 3091 DRCKMNPCLNGGTC--YPTETSYVCTCVPGYSGDQCELDFDECH--SNPCRNGATCVDGF 3146
D C NPC C P +CTC PG++G C+ D DEC +NPC + CV+
Sbjct: 353 DACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQ 412
Query: 3147 NTFRCLCLPSYVGALCEQDTETCDYGWHKFQGQC 3180
+F C C Y G CE D C G + Q C
Sbjct: 413 GSFLCQCGRGYTGPRCETDVNECLSGPCRNQATC 446
Score = 71.2 bits (173), Expect = 2e-11
Identities = 28/72 (38%), Positives = 38/72 (52%)
Query: 3098 CLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPSY 3157
C GG C ++S+ C C G +G CE + D C + PC++G TC + C CLP Y
Sbjct: 1055 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGY 1114
Query: 3158 VGALCEQDTETC 3169
G CE D + C
Sbjct: 1115 NGDNCEDDVDEC 1126
Score = 68.6 bits (166), Expect = 1e-10
Identities = 36/96 (37%), Positives = 46/96 (47%), Gaps = 3/96 (3%)
Query: 3088 PGPDRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGAT--CV-D 3144
PGP CL+ GTC + CTC PGY+G +CE D +EC S C T C+ D
Sbjct: 1166 PGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQD 1225
Query: 3145 GFNTFRCLCLPSYVGALCEQDTETCDYGWHKFQGQC 3180
FRCLC + G C+ C+ + GQC
Sbjct: 1226 PGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQC 1261
Score = 66.6 bits (161), Expect = 4e-10
Identities = 31/80 (38%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
D C+ PC GGTC + CTC PG G QCEL C NPC +G C
Sbjct: 736 DACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCEL-LSPCTPNPCEHGGRCESAPGQLP 794
Query: 3151 -CLCLPSYVGALCEQDTETC 3169
C C + G C+QD + C
Sbjct: 795 VCSCPQGWQGPRCQQDVDEC 814
Score = 65.1 bits (157), Expect = 1e-09
Identities = 34/93 (36%), Positives = 43/93 (46%), Gaps = 4/93 (4%)
Query: 3080 VEGTAIYLPGPDRCKMNPCLNGGTCYPTETSY-VCTCVPGYSGDQCELDFDECHSN-PCR 3137
V+G L P C NPC +GG C VC+C G+ G +C+ D DEC PC
Sbjct: 764 VQGRQCELLSP--CTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCG 821
Query: 3138 NGATCVDGFNTFRCLCLPSYVGALCEQDTETCD 3170
C + +F C C Y G C+QD CD
Sbjct: 822 PHGICTNLAGSFSCTCHGGYTGPSCDQDINDCD 854
Score = 60.1 bits (144), Expect = 4e-08
Identities = 31/87 (35%), Positives = 39/87 (44%), Gaps = 6/87 (6%)
Query: 3091 DRCKMNPCLNGGTCYPTETS----YVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGF 3146
D C PC G C + + + C C G+ G C L D C S+PC +GA C G
Sbjct: 80 DPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLP-DPCLSSPCAHGARCSVGP 138
Query: 3147 N-TFRCLCLPSYVGALCEQDTETCDYG 3172
+ F C C P Y G C D + C G
Sbjct: 139 DGRFLCSCPPGYQGRSCRSDVDECRVG 165
Score = 56.6 bits (135), Expect = 4e-07
Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 1/74 (1%)
Query: 3091 DRCKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFR 3150
+ C +PC GG+C E + C C PG C C PC +G C D FR
Sbjct: 659 NECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHG-ICYDAPGGFR 717
Query: 3151 CLCLPSYVGALCEQ 3164
C+C P + G C Q
Sbjct: 718 CVCEPGWSGPRCSQ 731
Score = 53.9 bits (128), Expect = 3e-06
Identities = 27/72 (37%), Positives = 35/72 (48%), Gaps = 6/72 (8%)
Query: 3096 NPCLNGGTCYPTET-SYVCTCVPGYSGDQCELDFDECHSNPCRNGATC----VDGFNTFR 3150
+PC NGG C + C C PG+ G++C+L+ D CHS PC C V G F
Sbjct: 47 SPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGPCAGRGVCQSSVVAGTARFS 105
Query: 3151 CLCLPSYVGALC 3162
C C + G C
Sbjct: 106 CRCPRGFRGPDC 117
Score = 44.7 bits (104), Expect = 0.002
Identities = 22/75 (29%), Positives = 29/75 (38%), Gaps = 5/75 (6%)
Query: 3093 CKMNPCLNGGTCYPTE-----TSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFN 3147
C+ PC +GG C P+ ++ C C + G +CE C C G C
Sbjct: 1250 CESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPR 1309
Query: 3148 TFRCLCLPSYVGALC 3162
RC C P G C
Sbjct: 1310 GPRCACPPGLSGPSC 1324
Score = 40.8 bits (94), Expect = 0.023
Identities = 24/81 (29%), Positives = 29/81 (35%), Gaps = 10/81 (12%)
Query: 3093 CKMNPCLNGGTCYPTETSYVCTCVPGYSGDQCE--------LDFDECHSNPCRNGATCVD 3144
C+ C G C T C C PG SG C C + PC +G +C
Sbjct: 1293 CRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRP 1352
Query: 3145 G--FNTFRCLCLPSYVGALCE 3163
FRC C + G CE
Sbjct: 1353 APLAPFFRCACAQGWTGPRCE 1373
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 136,240,137
Number of Sequences: 37866
Number of extensions: 6730636
Number of successful extensions: 26866
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 231
Number of HSP's successfully gapped in prelim test: 486
Number of HSP's that attempted gapping in prelim test: 19164
Number of HSP's gapped (non-prelim): 4219
length of query: 3396
length of database: 18,247,518
effective HSP length: 121
effective length of query: 3275
effective length of database: 13,665,732
effective search space: 44755272300
effective search space used: 44755272300
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.