Search of human proteins with 21264365

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21264365 nucleoporin 98kD isoform 1 [Homo sapiens]
         (1800 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21264365 nucleoporin 98kD isoform 1 [Homo sapiens]                3628   0.0  
gi|56549645 nucleoporin 98kD isoform 4 [Homo sapiens]                2986   0.0  
gi|21264369 nucleoporin 98kD isoform 2 [Homo sapiens]                1850   0.0  
gi|56549643 nucleoporin 98kD isoform 3 [Homo sapiens]                1839   0.0  
gi|33946327 nucleoporin 214kDa [Homo sapiens]                         114   1e-24
gi|89276766 trophinin isoform 5 [Homo sapiens]                        111   6e-24
gi|62122917 filaggrin family member 2 [Homo sapiens]                   94   2e-18
gi|161016767 mucin 21 [Homo sapiens]                                   91   8e-18
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            86   2e-16
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]            86   2e-16
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]            86   2e-16
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            86   4e-16
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]            86   4e-16
gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ...    84   9e-16
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            84   2e-15
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]            84   2e-15
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            83   3e-15
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            83   3e-15
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]    81   8e-15
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    79   3e-14
gi|24430146 nucleoporin 153kDa [Homo sapiens]                          77   2e-13
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]           76   3e-13
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        74   1e-12
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    74   1e-12
gi|24497609 nucleoporin 62kDa [Homo sapiens]                           73   3e-12
gi|24497607 nucleoporin 62kDa [Homo sapiens]                           73   3e-12
gi|24497605 nucleoporin 62kDa [Homo sapiens]                           73   3e-12
gi|24497603 nucleoporin 62kDa [Homo sapiens]                           73   3e-12
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ...    70   2e-11
gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]             69   3e-11

>gi|21264365 nucleoporin 98kD isoform 1 [Homo sapiens]
          Length = 1800

 Score = 3628 bits (9408), Expect = 0.0
 Identities = 1800/1800 (100%), Positives = 1800/1800 (100%)

Query: 1    MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG 60
            MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG
Sbjct: 1    MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG 60

Query: 61   GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF 120
            GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF
Sbjct: 61   GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF 120

Query: 121  GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180
            GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST
Sbjct: 121  GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180

Query: 181  NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240
            NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL
Sbjct: 181  NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240

Query: 241  FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300
            FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF
Sbjct: 241  FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300

Query: 301  SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV 360
            SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV
Sbjct: 301  SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV 360

Query: 361  GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGF 420
            GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGF
Sbjct: 361  GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGF 420

Query: 421  GTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQ 480
            GTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQ
Sbjct: 421  GTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQ 480

Query: 481  QAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPA 540
            QAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPA
Sbjct: 481  QAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPA 540

Query: 541  TRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKLVLKNLNNSNLFSPVNRD 600
            TRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKLVLKNLNNSNLFSPVNRD
Sbjct: 541  TRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKLVLKNLNNSNLFSPVNRD 600

Query: 601  SENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYTNPIAKPIPQTPESAGNK 660
            SENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYTNPIAKPIPQTPESAGNK
Sbjct: 601  SENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYTNPIAKPIPQTPESAGNK 660

Query: 661  HSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDREEIENNSYHMHPAGIILT 720
            HSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDREEIENNSYHMHPAGIILT
Sbjct: 661  HSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDREEIENNSYHMHPAGIILT 720

Query: 721  KVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDIVHIRRK 780
            KVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDIVHIRRK
Sbjct: 721  KVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDIVHIRRK 780

Query: 781  EVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEAVSR 840
            EVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEAVSR
Sbjct: 781  EVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEAVSR 840

Query: 841  KQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTSTKKLKTAPLPPASQTTP 900
            KQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTSTKKLKTAPLPPASQTTP
Sbjct: 841  KQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTSTKKLKTAPLPPASQTTP 900

Query: 901  LQMALNGKPAPPPQSQSPEVEQLGRVVELDSDMVDITQEPVLDTMLEESMPEDQEPVSAS 960
            LQMALNGKPAPPPQSQSPEVEQLGRVVELDSDMVDITQEPVLDTMLEESMPEDQEPVSAS
Sbjct: 901  LQMALNGKPAPPPQSQSPEVEQLGRVVELDSDMVDITQEPVLDTMLEESMPEDQEPVSAS 960

Query: 961  THIASSLGINPHVLQIMKASLLTDEEDVDMALDQRFSRLPSKADTSQEICSPRLPISASH 1020
            THIASSLGINPHVLQIMKASLLTDEEDVDMALDQRFSRLPSKADTSQEICSPRLPISASH
Sbjct: 961  THIASSLGINPHVLQIMKASLLTDEEDVDMALDQRFSRLPSKADTSQEICSPRLPISASH 1020

Query: 1021 SSKTRSLVGGLLQSKFTSGAFLSPSVSVQECRTPRAASLMNIPSTSSWSVPPPLTSVFTM 1080
            SSKTRSLVGGLLQSKFTSGAFLSPSVSVQECRTPRAASLMNIPSTSSWSVPPPLTSVFTM
Sbjct: 1021 SSKTRSLVGGLLQSKFTSGAFLSPSVSVQECRTPRAASLMNIPSTSSWSVPPPLTSVFTM 1080

Query: 1081 PSPAPEVPLKTVGTRRQLGLVPREKSVTYGKGKLLMDMALFMGRSFRVGWGPNWTLANSG 1140
            PSPAPEVPLKTVGTRRQLGLVPREKSVTYGKGKLLMDMALFMGRSFRVGWGPNWTLANSG
Sbjct: 1081 PSPAPEVPLKTVGTRRQLGLVPREKSVTYGKGKLLMDMALFMGRSFRVGWGPNWTLANSG 1140

Query: 1141 EQLNGSHELENHQIADSMEFGFLPNPVAVKPLTESPFKVHLEKLSLRQRKPDEDMKLYQT 1200
            EQLNGSHELENHQIADSMEFGFLPNPVAVKPLTESPFKVHLEKLSLRQRKPDEDMKLYQT
Sbjct: 1141 EQLNGSHELENHQIADSMEFGFLPNPVAVKPLTESPFKVHLEKLSLRQRKPDEDMKLYQT 1200

Query: 1201 PLELKLKHSTVHVDELCPLIVPNLGVAVIHDYADWVKEASGDLPEAQIVKHWSLTWTLCE 1260
            PLELKLKHSTVHVDELCPLIVPNLGVAVIHDYADWVKEASGDLPEAQIVKHWSLTWTLCE
Sbjct: 1201 PLELKLKHSTVHVDELCPLIVPNLGVAVIHDYADWVKEASGDLPEAQIVKHWSLTWTLCE 1260

Query: 1261 ALWGHLKELDSQLNEPREYIQILERRRAFSRWLSCTATPQIEEEVSLTQKNSPVEAVFSY 1320
            ALWGHLKELDSQLNEPREYIQILERRRAFSRWLSCTATPQIEEEVSLTQKNSPVEAVFSY
Sbjct: 1261 ALWGHLKELDSQLNEPREYIQILERRRAFSRWLSCTATPQIEEEVSLTQKNSPVEAVFSY 1320

Query: 1321 LTGKRISEACSLAQQSGDHRLALLLSQFVGSQSVRELLTMQLVDWHQLQADSFIQDERLR 1380
            LTGKRISEACSLAQQSGDHRLALLLSQFVGSQSVRELLTMQLVDWHQLQADSFIQDERLR
Sbjct: 1321 LTGKRISEACSLAQQSGDHRLALLLSQFVGSQSVRELLTMQLVDWHQLQADSFIQDERLR 1380

Query: 1381 IFALLAGKPVWQLSEKKQINVCSQLDWKRSLAIHLWYLLPPTASISRALSMYEEAFQNTS 1440
            IFALLAGKPVWQLSEKKQINVCSQLDWKRSLAIHLWYLLPPTASISRALSMYEEAFQNTS
Sbjct: 1381 IFALLAGKPVWQLSEKKQINVCSQLDWKRSLAIHLWYLLPPTASISRALSMYEEAFQNTS 1440

Query: 1441 DSDRYACSPLPSYLEGSGCVIAEEQNSQTPLRDVCFHLLKLYSDRHYDLNQLLEPRSITA 1500
            DSDRYACSPLPSYLEGSGCVIAEEQNSQTPLRDVCFHLLKLYSDRHYDLNQLLEPRSITA
Sbjct: 1441 DSDRYACSPLPSYLEGSGCVIAEEQNSQTPLRDVCFHLLKLYSDRHYDLNQLLEPRSITA 1500

Query: 1501 DPLDYRLSWHLWEVLRALNYTHLSAQCEGVLQASYAGQLESEGLWEWAIFVLLHIDNSGI 1560
            DPLDYRLSWHLWEVLRALNYTHLSAQCEGVLQASYAGQLESEGLWEWAIFVLLHIDNSGI
Sbjct: 1501 DPLDYRLSWHLWEVLRALNYTHLSAQCEGVLQASYAGQLESEGLWEWAIFVLLHIDNSGI 1560

Query: 1561 REKAVRELLTRHCQLLETPESWAKETFLTQKLRVPAKWIHEAKAVRAHMESDKHLEALCL 1620
            REKAVRELLTRHCQLLETPESWAKETFLTQKLRVPAKWIHEAKAVRAHMESDKHLEALCL
Sbjct: 1561 REKAVRELLTRHCQLLETPESWAKETFLTQKLRVPAKWIHEAKAVRAHMESDKHLEALCL 1620

Query: 1621 FKAEHWNRCHKLIIRHLASDAIINENYDYLKGFLEDLAPPERSSLIQDWETSGLVYLDYI 1680
            FKAEHWNRCHKLIIRHLASDAIINENYDYLKGFLEDLAPPERSSLIQDWETSGLVYLDYI
Sbjct: 1621 FKAEHWNRCHKLIIRHLASDAIINENYDYLKGFLEDLAPPERSSLIQDWETSGLVYLDYI 1680

Query: 1681 RVIEMLRHIQQVDCSGNDLEQLHIKVTSLCSRIEQIQCYSAKDRLAQSDMAKRVANLLRV 1740
            RVIEMLRHIQQVDCSGNDLEQLHIKVTSLCSRIEQIQCYSAKDRLAQSDMAKRVANLLRV
Sbjct: 1681 RVIEMLRHIQQVDCSGNDLEQLHIKVTSLCSRIEQIQCYSAKDRLAQSDMAKRVANLLRV 1740

Query: 1741 VLSLHHPPDRTSDSTPDPQRVPLRLLAPHIGRLPMPEDYAMDELRSLTQSYLRELAVGSL 1800
            VLSLHHPPDRTSDSTPDPQRVPLRLLAPHIGRLPMPEDYAMDELRSLTQSYLRELAVGSL
Sbjct: 1741 VLSLHHPPDRTSDSTPDPQRVPLRLLAPHIGRLPMPEDYAMDELRSLTQSYLRELAVGSL 1800


>gi|56549645 nucleoporin 98kD isoform 4 [Homo sapiens]
          Length = 1726

 Score = 2986 bits (7742), Expect = 0.0
 Identities = 1484/1484 (100%), Positives = 1484/1484 (100%)

Query: 1    MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG 60
            MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG
Sbjct: 1    MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG 60

Query: 61   GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF 120
            GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF
Sbjct: 61   GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF 120

Query: 121  GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180
            GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST
Sbjct: 121  GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180

Query: 181  NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240
            NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL
Sbjct: 181  NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240

Query: 241  FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300
            FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF
Sbjct: 241  FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300

Query: 301  SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV 360
            SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV
Sbjct: 301  SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV 360

Query: 361  GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGF 420
            GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGF
Sbjct: 361  GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGF 420

Query: 421  GTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQ 480
            GTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQ
Sbjct: 421  GTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQ 480

Query: 481  QAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPA 540
            QAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPA
Sbjct: 481  QAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPA 540

Query: 541  TRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKLVLKNLNNSNLFSPVNRD 600
            TRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKLVLKNLNNSNLFSPVNRD
Sbjct: 541  TRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKLVLKNLNNSNLFSPVNRD 600

Query: 601  SENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYTNPIAKPIPQTPESAGNK 660
            SENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYTNPIAKPIPQTPESAGNK
Sbjct: 601  SENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYTNPIAKPIPQTPESAGNK 660

Query: 661  HSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDREEIENNSYHMHPAGIILT 720
            HSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDREEIENNSYHMHPAGIILT
Sbjct: 661  HSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDREEIENNSYHMHPAGIILT 720

Query: 721  KVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDIVHIRRK 780
            KVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDIVHIRRK
Sbjct: 721  KVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDIVHIRRK 780

Query: 781  EVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEAVSR 840
            EVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEAVSR
Sbjct: 781  EVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEAVSR 840

Query: 841  KQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTSTKKLKTAPLPPASQTTP 900
            KQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTSTKKLKTAPLPPASQTTP
Sbjct: 841  KQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTSTKKLKTAPLPPASQTTP 900

Query: 901  LQMALNGKPAPPPQSQSPEVEQLGRVVELDSDMVDITQEPVLDTMLEESMPEDQEPVSAS 960
            LQMALNGKPAPPPQSQSPEVEQLGRVVELDSDMVDITQEPVLDTMLEESMPEDQEPVSAS
Sbjct: 901  LQMALNGKPAPPPQSQSPEVEQLGRVVELDSDMVDITQEPVLDTMLEESMPEDQEPVSAS 960

Query: 961  THIASSLGINPHVLQIMKASLLTDEEDVDMALDQRFSRLPSKADTSQEICSPRLPISASH 1020
            THIASSLGINPHVLQIMKASLLTDEEDVDMALDQRFSRLPSKADTSQEICSPRLPISASH
Sbjct: 961  THIASSLGINPHVLQIMKASLLTDEEDVDMALDQRFSRLPSKADTSQEICSPRLPISASH 1020

Query: 1021 SSKTRSLVGGLLQSKFTSGAFLSPSVSVQECRTPRAASLMNIPSTSSWSVPPPLTSVFTM 1080
            SSKTRSLVGGLLQSKFTSGAFLSPSVSVQECRTPRAASLMNIPSTSSWSVPPPLTSVFTM
Sbjct: 1021 SSKTRSLVGGLLQSKFTSGAFLSPSVSVQECRTPRAASLMNIPSTSSWSVPPPLTSVFTM 1080

Query: 1081 PSPAPEVPLKTVGTRRQLGLVPREKSVTYGKGKLLMDMALFMGRSFRVGWGPNWTLANSG 1140
            PSPAPEVPLKTVGTRRQLGLVPREKSVTYGKGKLLMDMALFMGRSFRVGWGPNWTLANSG
Sbjct: 1081 PSPAPEVPLKTVGTRRQLGLVPREKSVTYGKGKLLMDMALFMGRSFRVGWGPNWTLANSG 1140

Query: 1141 EQLNGSHELENHQIADSMEFGFLPNPVAVKPLTESPFKVHLEKLSLRQRKPDEDMKLYQT 1200
            EQLNGSHELENHQIADSMEFGFLPNPVAVKPLTESPFKVHLEKLSLRQRKPDEDMKLYQT
Sbjct: 1141 EQLNGSHELENHQIADSMEFGFLPNPVAVKPLTESPFKVHLEKLSLRQRKPDEDMKLYQT 1200

Query: 1201 PLELKLKHSTVHVDELCPLIVPNLGVAVIHDYADWVKEASGDLPEAQIVKHWSLTWTLCE 1260
            PLELKLKHSTVHVDELCPLIVPNLGVAVIHDYADWVKEASGDLPEAQIVKHWSLTWTLCE
Sbjct: 1201 PLELKLKHSTVHVDELCPLIVPNLGVAVIHDYADWVKEASGDLPEAQIVKHWSLTWTLCE 1260

Query: 1261 ALWGHLKELDSQLNEPREYIQILERRRAFSRWLSCTATPQIEEEVSLTQKNSPVEAVFSY 1320
            ALWGHLKELDSQLNEPREYIQILERRRAFSRWLSCTATPQIEEEVSLTQKNSPVEAVFSY
Sbjct: 1261 ALWGHLKELDSQLNEPREYIQILERRRAFSRWLSCTATPQIEEEVSLTQKNSPVEAVFSY 1320

Query: 1321 LTGKRISEACSLAQQSGDHRLALLLSQFVGSQSVRELLTMQLVDWHQLQADSFIQDERLR 1380
            LTGKRISEACSLAQQSGDHRLALLLSQFVGSQSVRELLTMQLVDWHQLQADSFIQDERLR
Sbjct: 1321 LTGKRISEACSLAQQSGDHRLALLLSQFVGSQSVRELLTMQLVDWHQLQADSFIQDERLR 1380

Query: 1381 IFALLAGKPVWQLSEKKQINVCSQLDWKRSLAIHLWYLLPPTASISRALSMYEEAFQNTS 1440
            IFALLAGKPVWQLSEKKQINVCSQLDWKRSLAIHLWYLLPPTASISRALSMYEEAFQNTS
Sbjct: 1381 IFALLAGKPVWQLSEKKQINVCSQLDWKRSLAIHLWYLLPPTASISRALSMYEEAFQNTS 1440

Query: 1441 DSDRYACSPLPSYLEGSGCVIAEEQNSQTPLRDVCFHLLKLYSD 1484
            DSDRYACSPLPSYLEGSGCVIAEEQNSQTPLRDVCFHLLKLYSD
Sbjct: 1441 DSDRYACSPLPSYLEGSGCVIAEEQNSQTPLRDVCFHLLKLYSD 1484



 Score =  493 bits (1269), Expect = e-139
 Identities = 244/251 (97%), Positives = 246/251 (98%)

Query: 1550 FVLLHIDNSGIREKAVRELLTRHCQLLETPESWAKETFLTQKLRVPAKWIHEAKAVRAHM 1609
            F LL + +  IREKAVRELLTRHCQLLETPESWAKETFLTQKLRVPAKWIHEAKAVRAHM
Sbjct: 1476 FHLLKLYSDSIREKAVRELLTRHCQLLETPESWAKETFLTQKLRVPAKWIHEAKAVRAHM 1535

Query: 1610 ESDKHLEALCLFKAEHWNRCHKLIIRHLASDAIINENYDYLKGFLEDLAPPERSSLIQDW 1669
            ESDKHLEALCLFKAEHWNRCHKLIIRHLASDAIINENYDYLKGFLEDLAPPERSSLIQDW
Sbjct: 1536 ESDKHLEALCLFKAEHWNRCHKLIIRHLASDAIINENYDYLKGFLEDLAPPERSSLIQDW 1595

Query: 1670 ETSGLVYLDYIRVIEMLRHIQQVDCSGNDLEQLHIKVTSLCSRIEQIQCYSAKDRLAQSD 1729
            ETSGLVYLDYIRVIEMLRHIQQVDCSGNDLEQLHIKVTSLCSRIEQIQCYSAKDRLAQSD
Sbjct: 1596 ETSGLVYLDYIRVIEMLRHIQQVDCSGNDLEQLHIKVTSLCSRIEQIQCYSAKDRLAQSD 1655

Query: 1730 MAKRVANLLRVVLSLHHPPDRTSDSTPDPQRVPLRLLAPHIGRLPMPEDYAMDELRSLTQ 1789
            MAKRVANLLRVVLSLHHPPDRTSDSTPDPQRVPLRLLAPHIGRLPMPEDYAMDELRSLTQ
Sbjct: 1656 MAKRVANLLRVVLSLHHPPDRTSDSTPDPQRVPLRLLAPHIGRLPMPEDYAMDELRSLTQ 1715

Query: 1790 SYLRELAVGSL 1800
            SYLRELAVGSL
Sbjct: 1716 SYLRELAVGSL 1726


>gi|21264369 nucleoporin 98kD isoform 2 [Homo sapiens]
          Length = 920

 Score = 1850 bits (4791), Expect = 0.0
 Identities = 914/914 (100%), Positives = 914/914 (100%)

Query: 1   MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG 60
           MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG
Sbjct: 1   MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG 60

Query: 61  GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF 120
           GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF
Sbjct: 61  GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF 120

Query: 121 GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180
           GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST
Sbjct: 121 GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180

Query: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240
           NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL
Sbjct: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240

Query: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300
           FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF
Sbjct: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300

Query: 301 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV 360
           SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV
Sbjct: 301 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV 360

Query: 361 GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGF 420
           GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGF
Sbjct: 361 GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGF 420

Query: 421 GTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQ 480
           GTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQ
Sbjct: 421 GTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQ 480

Query: 481 QAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPA 540
           QAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPA
Sbjct: 481 QAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPA 540

Query: 541 TRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKLVLKNLNNSNLFSPVNRD 600
           TRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKLVLKNLNNSNLFSPVNRD
Sbjct: 541 TRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKLVLKNLNNSNLFSPVNRD 600

Query: 601 SENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYTNPIAKPIPQTPESAGNK 660
           SENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYTNPIAKPIPQTPESAGNK
Sbjct: 601 SENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYTNPIAKPIPQTPESAGNK 660

Query: 661 HSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDREEIENNSYHMHPAGIILT 720
           HSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDREEIENNSYHMHPAGIILT
Sbjct: 661 HSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDREEIENNSYHMHPAGIILT 720

Query: 721 KVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDIVHIRRK 780
           KVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDIVHIRRK
Sbjct: 721 KVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDIVHIRRK 780

Query: 781 EVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEAVSR 840
           EVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEAVSR
Sbjct: 781 EVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEAVSR 840

Query: 841 KQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTSTKKLKTAPLPPASQTTP 900
           KQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTSTKKLKTAPLPPASQTTP
Sbjct: 841 KQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTSTKKLKTAPLPPASQTTP 900

Query: 901 LQMALNGKPAPPPQ 914
           LQMALNGKPAPPPQ
Sbjct: 901 LQMALNGKPAPPPQ 914


>gi|56549643 nucleoporin 98kD isoform 3 [Homo sapiens]
          Length = 937

 Score = 1839 bits (4763), Expect = 0.0
 Identities = 914/931 (98%), Positives = 914/931 (98%), Gaps = 17/931 (1%)

Query: 1   MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG 60
           MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG
Sbjct: 1   MFNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG 60

Query: 61  GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF 120
           GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF
Sbjct: 61  GLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF 120

Query: 121 GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180
           GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST
Sbjct: 121 GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180

Query: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240
           NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL
Sbjct: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240

Query: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300
           FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF
Sbjct: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300

Query: 301 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV 360
           SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV
Sbjct: 301 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAV 360

Query: 361 GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFG-----------------FGTNTSGNSIF 403
           GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFG                 FGTNTSGNSIF
Sbjct: 361 GSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNTSGNSIF 420

Query: 404 GSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG 463
           GSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG
Sbjct: 421 GSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG 480

Query: 464 APQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAA 523
           APQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAA
Sbjct: 481 APQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAA 540

Query: 524 QKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKL 583
           QKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKL
Sbjct: 541 QKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKL 600

Query: 584 VLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYT 643
           VLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYT
Sbjct: 601 VLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYT 660

Query: 644 NPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDRE 703
           NPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDRE
Sbjct: 661 NPIAKPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFHDESLQDDRE 720

Query: 704 EIENNSYHMHPAGIILTKVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGD 763
           EIENNSYHMHPAGIILTKVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGD
Sbjct: 721 EIENNSYHMHPAGIILTKVGYYTIPSMDDLAKITNEKGECIVSDFTIGRKGYGSIYFEGD 780

Query: 764 VNLTNLNLDDIVHIRRKEVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSP 823
           VNLTNLNLDDIVHIRRKEVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSP
Sbjct: 781 VNLTNLNLDDIVHIRRKEVVVYLDDNQKPPVGEGLNRKAEVTLDGVWPTDKTSRCLIKSP 840

Query: 824 DRLADINYEGRLEAVSRKQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTS 883
           DRLADINYEGRLEAVSRKQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTS
Sbjct: 841 DRLADINYEGRLEAVSRKQGAQFKEYRPETGSWVFKVSHFSKYGLQDSDEEEEEHPSKTS 900

Query: 884 TKKLKTAPLPPASQTTPLQMALNGKPAPPPQ 914
           TKKLKTAPLPPASQTTPLQMALNGKPAPPPQ
Sbjct: 901 TKKLKTAPLPPASQTTPLQMALNGKPAPPPQ 931


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score =  114 bits (284), Expect = 1e-24
 Identities = 126/457 (27%), Positives = 192/457 (42%), Gaps = 78/457 (17%)

Query: 8    TPFGGGTGGFGTTSTFGQNTG---------------------FGTTSGGAFGTSAFGSSN 46
            TP  G        S FGQ TG                     FGTT+ G FG + FG ++
Sbjct: 1671 TPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQTTFGQAS 1730

Query: 47   NTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFG---FGTSTGTANTLFGTASTGTSLFS 103
                +FG S +    +F   SFSQP  S+   FG     T T T+ ++FG AS   S  S
Sbjct: 1731 ----VFGQSASSAASVF---SFSQPGFSSVPAFGQPASSTPTSTSGSVFGAAS---STSS 1780

Query: 104  SQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTS---NPFGSTSGSLFGPSSFTAAPTGT 160
            S + +F Q+ P          + GGLFG +N  +   +P     GS+FG +S       T
Sbjct: 1781 SSSFSFGQSSP---------NTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAAT 1831

Query: 161  T-IKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQV 219
            +   F   +G  +     V    ++    +    +  S S   +          G  + +
Sbjct: 1832 SGFSFCQASGFGSSNTGSVFGQAASTGGIV--FGQQSSSSSGSVFGSGNTGRGGGFFSGL 1889

Query: 220  GAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQN--KTAFGTSTTGFG-TNPGGLFGQ 276
            G   +      +P +S++ G  S++T+N+   +G +  KT  G +++ FG   P G F  
Sbjct: 1890 GGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSS 1949

Query: 277  QNQQTTSLFSKPFGQATTTQNTGFS----FGNTSTI-GQPSTNTMGLFGVTQASQPGGLF 331
                  S+ S+ FG ++  +  GF     FG+  T  G P    +  FG   A      F
Sbjct: 1950 GG---GSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPA------F 2000

Query: 332  GTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGS-STTSAPSFGTTSGGL 390
             +   ++ G  FG GT        GFG+  +T       T+FG+ ++ +AP+FG+ S   
Sbjct: 2001 TSPLGSTGGKVFGEGTAAASAGGFGFGSSSNT-------TSFGTLASQNAPTFGSLSQQT 2053

Query: 391  FGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAG 427
             GFGT +SG S FGS    GT G   G+   +  G G
Sbjct: 2054 SGFGTQSSGFSGFGS----GTGGFSFGSNNSSVQGFG 2086



 Score =  102 bits (254), Expect = 3e-21
 Identities = 134/491 (27%), Positives = 199/491 (40%), Gaps = 115/491 (23%)

Query: 93   GTASTGTSLFSSQNNAFAQNKPTGFGNFGTST----SSGGLFGTTNTTSNPFGSTSGSLF 148
            GTA++ TSL +   +A A    TG  +  T      SS  + G T  T+    S++G + 
Sbjct: 1552 GTAASSTSLVAL--SAEATPATTGVPDARTEAVPPASSFSVPGQTAVTAAAI-SSAGPVA 1608

Query: 149  GPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDY 208
              +S T   + TT    P    +      V++  S   Q   A     S +  +L     
Sbjct: 1609 VETSSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASS---SSAFNQLTNNTA 1665

Query: 209  QANRKGPQ-NQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFG 267
             A    P   QV A T   LFG    ++++T   +   ++SGF           S+  FG
Sbjct: 1666 TAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGF-----------SSPAFG 1714

Query: 268  TNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQP 327
            T   G+FGQ    TT   +  FGQ+ ++  + FSF       QP  +++  FG   +S P
Sbjct: 1715 TTAPGVFGQ----TTFGQASVFGQSASSAASVFSFS------QPGFSSVPAFGQPASSTP 1764

Query: 328  ----GGLFGTATNTSTGTAFG-------TGTGLFGQTNT-------GFGAVGSTLFGNNK 369
                G +FG A++TS+ ++F        TG GLFGQ+N        GFG  GS   G + 
Sbjct: 1765 TSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSA 1824

Query: 370  LTT--------------FGSSTTSAPSFG---TTSGGLFGFGTNTSGNSIFGSKPAP--G 410
             TT              FGSS T +  FG   +T G +FG  +++S  S+FGS      G
Sbjct: 1825 ATTTAATSGFSFCQASGFGSSNTGSV-FGQAASTGGIVFGQQSSSSSGSVFGSGNTGRGG 1883

Query: 411  TLGTGLGA-----------------GFGTALGAGQASLFGNNQPKIGGPLGTGAFGAP-- 451
               +GLG                  GFG+   +  ++LFGN+  K  G   + +FG    
Sbjct: 1884 GFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKP 1943

Query: 452  ----------------GFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSP 495
                            GF++   T GFGA  APV  + P    +                
Sbjct: 1944 TGTFSSGGGSVASQGFGFSSPNKTGGFGA--APVFGSPPTFGGSP--------GFGGVPA 1993

Query: 496  FGDSPLFRNPM 506
            FG +P F +P+
Sbjct: 1994 FGSAPAFTSPL 2004



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 137/510 (26%), Positives = 194/510 (38%), Gaps = 89/510 (17%)

Query: 8    TPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTS---AFGSSNNTGGLFGNSQTKPGGLFG 64
            TP    T          +   FGT + G+   +   A  SS+    L  N+ T P     
Sbjct: 1614 TPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASSSSAFNQLTNNTATAPSA--- 1670

Query: 65   TSSFSQPATSTSTGFGFGTSTG-TANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTS 123
            T  F Q A ST+    FG  TG TA+T   T    +S FSS   AF    P  FG   T+
Sbjct: 1671 TPVFGQVAASTAPSL-FGQQTGSTASTAAATPQVSSSGFSSP--AFGTTAPGVFGQ--TT 1725

Query: 124  TSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIS 183
                 +FG + +++    S     F    F++ P       + PT T   V    S+  S
Sbjct: 1726 FGQASVFGQSASSAASVFS-----FSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSS 1780

Query: 184  TKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSS 243
            +               L             G  N    G + G FG   +    T   ++
Sbjct: 1781 SSSFSFGQSSPNTGGGLF------------GQSNAPAFGQSPG-FGQGGSVFGGTSAATT 1827

Query: 244  STTNSGFAYGQNKTAFGTSTTG--FG--TNPGGL-FGQQNQQTTSLFSKPFGQATTTQNT 298
            +   SGF++ Q  + FG+S TG  FG   + GG+ FGQQ+  ++      FG   T +  
Sbjct: 1828 TAATSGFSFCQ-ASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSG---SVFGSGNTGRGG 1883

Query: 299  GFSFGNTSTIGQ------PSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQ 352
            GF  G      Q      P ++  G FG T  S    LFG   N+   T  G  +  FG+
Sbjct: 1884 GFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFG---NSGAKTFGGFASSSFGE 1940

Query: 353  T------NTGFGAVGSTLFG---NNKLTTFGSSTT--------------------SAPSF 383
                   ++G G+V S  FG    NK   FG++                      SAP+F
Sbjct: 1941 QKPTGTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAF 2000

Query: 384  ----GTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKI 439
                G+T G +FG GT  +    FG   +  T        FGT L +  A  FG+   + 
Sbjct: 2001 TSPLGSTGGKVFGEGTAAASAGGFGFGSSSNT------TSFGT-LASQNAPTFGSLSQQT 2053

Query: 440  GGPLGTGAFGAPGFNTTTATLGFGAPQAPV 469
             G  GT + G  GF + T    FG+  + V
Sbjct: 2054 SG-FGTQSSGFSGFGSGTGGFSFGSNNSSV 2082



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 120/408 (29%), Positives = 170/408 (41%), Gaps = 67/408 (16%)

Query: 5    SFGTPFGGGTGGFGTTSTFGQNTGFG--TTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGL 62
            S  + F     GF +   FGQ       +TSG  FG ++  SS+++     +S    GGL
Sbjct: 1738 SAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGL 1797

Query: 63   FGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGT 122
            FG S  + PA   S GFG G S      +FG  S  T+  ++   +F Q   +GFG    
Sbjct: 1798 FGQS--NAPAFGQSPGFGQGGS------VFGGTSAATTTAATSGFSFCQ--ASGFG---- 1843

Query: 123  STSSGGLFGTTNTTSN-PFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTN 181
            S+++G +FG   +T    FG  S S  G S F +  TG    F    G         S +
Sbjct: 1844 SSNTGSVFGQAASTGGIVFGQQSSSSSG-SVFGSGNTGRGGGFFSGLG------GKPSQD 1896

Query: 182  ISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLF 241
             + K+   +A   + S +          +N        GA T  G   SS      TG F
Sbjct: 1897 AANKNPFSSASGGFGSTA---------TSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTF 1947

Query: 242  SS---STTNSGFAYGQ-NKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQN 297
            SS   S  + GF +   NKT       GFG  P  +FG      T   S  FG       
Sbjct: 1948 SSGGGSVASQGFGFSSPNKTG------GFGAAP--VFG---SPPTFGGSPGFGGVP---- 1992

Query: 298  TGFSFGNTSTIGQPSTNTMG-LFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTG 356
               +FG+      P  +T G +FG   A+   G FG  ++++T T+FGT   L  Q    
Sbjct: 1993 ---AFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFGFGSSSNT-TSFGT---LASQNAPT 2045

Query: 357  FGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFG 404
            FG++     G      FG+ ++    FG+ +GG F FG+N S    FG
Sbjct: 2046 FGSLSQQTSG------FGTQSSGFSGFGSGTGG-FSFGSNNSSVQGFG 2086



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 51/143 (35%), Positives = 68/143 (47%), Gaps = 16/143 (11%)

Query: 3    NKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGL 62
            ++ FG      TGGFG    FG    FG  S G  G  AFGS+         + T P G 
Sbjct: 1956 SQGFGFSSPNKTGGFGAAPVFGSPPTFG-GSPGFGGVPAFGSA--------PAFTSPLGS 2006

Query: 63   FGTSSFSQ-PATSTSTGFGFGTSTGTANTLFGT-ASTGTSLFS--SQNNAFAQNKPTGFG 118
             G   F +  A +++ GFGFG+S+ T  T FGT AS     F   SQ  +    + +GF 
Sbjct: 2007 TGGKVFGEGTAAASAGGFGFGSSSNT--TSFGTLASQNAPTFGSLSQQTSGFGTQSSGFS 2064

Query: 119  NFGTSTSSGGLFGTTNTTSNPFG 141
             FG+ T  G  FG+ N++   FG
Sbjct: 2065 GFGSGT-GGFSFGSNNSSVQGFG 2086



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 105/467 (22%), Positives = 164/467 (35%), Gaps = 80/467 (17%)

Query: 69   SQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGG 128
            + PAT  ST  G      TA T     +   +  + Q +     KP+G        SSG 
Sbjct: 1130 NNPATP-STAMGSSVPYSTAKTPHPVLTPVAANQAKQGSLINSLKPSGPTPASGQLSSGD 1188

Query: 129  -LFGT----TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIS 183
               GT    T  TS P  S SG    P SF+  P+GT   F   T T        S+N +
Sbjct: 1189 KASGTAKIETAVTSTP--SASGQFSKPFSFS--PSGTGFNFGIITPTP-------SSNFT 1237

Query: 184  TKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSS 243
                   + KE                    P      G +   + + P +S  +G+ S+
Sbjct: 1238 AAQGATPSTKESSQ-----------------PDAFSSGGGSKPSYEAIPESSPPSGITSA 1280

Query: 244  STTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFG 303
            S T  G     +      S T   T    L    ++    LF       T    +G   G
Sbjct: 1281 SNTTPGEPAASSSRPVAPSGTALSTTSSKLETPPSKLGELLFPSSLAGETLGSFSGLRVG 1340

Query: 304  NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363
                  +P+                     A++TS  +   T T       +GF      
Sbjct: 1341 QADDSTKPTNK-------------------ASSTSLTSTQPTKTS---GVPSGFNFTAPP 1378

Query: 364  LFGNNK---LTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGF 420
            + G +    +T+  ++T+ AP   T+          TS  ++FGS P      +G+ +  
Sbjct: 1379 VLGKHTEPPVTSSATTTSVAPPAATS----------TSSTAVFGSLPVTSAGSSGVISFG 1428

Query: 421  GTALGAGQASL-FGNNQ-----PKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDP 474
            GT+L AG+ S  FG+ Q     P    P  T A   P   T+  TL FG+  +  + T P
Sbjct: 1429 GTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLP---TSFPTLSFGSLLS--SATTP 1483

Query: 475  NASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNP 521
            +   +     ++  +S      GDS +  +  S  ++++    P  P
Sbjct: 1484 SLPMSAGRSTEEATSSALPEKPGDSEVSASAASLLEEQQSAQLPQAP 1530



 Score = 38.9 bits (89), Expect = 0.046
 Identities = 69/316 (21%), Positives = 118/316 (37%), Gaps = 45/316 (14%)

Query: 18   GTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77
            G T   GQ +     SG A   +A  S+ +  G F    +KP        FS   + T  
Sbjct: 1176 GPTPASGQLSSGDKASGTAKIETAVTSTPSASGQF----SKP--------FSFSPSGTGF 1223

Query: 78   GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ---NKPTGFGNFGTSTSSGGLFGTTN 134
             FG  T T ++N      +T ++  SSQ +AF+    +KP+ +     S+   G+   +N
Sbjct: 1224 NFGIITPTPSSNFTAAQGATPSTKESSQPDAFSSGGGSKPS-YEAIPESSPPSGITSASN 1282

Query: 135  TTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMV-------------------K 175
            TT     ++S     PS    + T + ++  PP+    ++                   +
Sbjct: 1283 TTPGEPAASSSRPVAPSGTALSTTSSKLE-TPPSKLGELLFPSSLAGETLGSFSGLRVGQ 1341

Query: 176  AGVSTNISTKHQCITAMKEYESKSLEELRLEDYQA----NRKGPQNQVGAGTTTGLFGSS 231
            A  ST  + K    +      +K+       ++ A     +        + TTT +   +
Sbjct: 1342 ADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTAPPVLGKHTEPPVTSSATTTSVAPPA 1401

Query: 232  PATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQ 291
              ++S+T +F S    S  + G    +FG ++   G        QQ   T    + P   
Sbjct: 1402 ATSTSSTAVFGSLPVTSAGSSG--VISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTT 1459

Query: 292  ATTTQNTGF---SFGN 304
            A T   T F   SFG+
Sbjct: 1460 AATPLPTSFPTLSFGS 1475



 Score = 37.4 bits (85), Expect = 0.13
 Identities = 36/116 (31%), Positives = 46/116 (39%), Gaps = 26/116 (22%)

Query: 6    FGTP-FGGGTGGFGTTSTFGQNTGF----GTTSGGAFGTSA---------FGSSNNTGGL 51
            FG+P   GG+ GFG    FG    F    G+T G  FG            FGSS+NT   
Sbjct: 1976 FGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFGFGSSSNTTSF 2035

Query: 52   ----------FGNSQTKPGGLFGTSSFSQPATSTSTG-FGFGTSTGTANTLFGTAS 96
                      FG+   +  G FGT S       + TG F FG++  +     G  S
Sbjct: 2036 GTLASQNAPTFGSLSQQTSG-FGTQSSGFSGFGSGTGGFSFGSNNSSVQGFGGWRS 2090


>gi|89276766 trophinin isoform 5 [Homo sapiens]
          Length = 1431

 Score =  111 bits (278), Expect = 6e-24
 Identities = 142/485 (29%), Positives = 194/485 (40%), Gaps = 68/485 (14%)

Query: 5    SFGTPFGGGTGGFGTTST---FGQNTGFGTTSGGAFGTS-AFGSSNNTGGLFG---NSQT 57
            SFG+     TG  G  ST   FG         GG+ GTS +FGS+ NT   +G   ++ T
Sbjct: 978  SFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGGSPGTSVSFGSALNTNAGYGGAVSTNT 1037

Query: 58   KPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSS--QNNAFAQNKPT 115
              GG   TS     + STS GFG   +T   N  FG A + ++ FS     +A     P 
Sbjct: 1038 DFGGTLSTSVCFGGSPSTSAGFGGALNT---NASFGCAVSTSASFSGAVSTSACFSGAPI 1094

Query: 116  GFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVK 175
                FG + S+   FG   +T+  FG T  +  G   F AAP+ T++ F    GT     
Sbjct: 1095 TNPGFGGAFSTSAGFGGALSTAADFGGTPSNSIG---FGAAPS-TSVSFGGAHGTSLCFG 1150

Query: 176  AGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVG--AGTTTGLFGSSPA 233
               ST++            + S S   L          GP +     +G T+  F   P+
Sbjct: 1151 GAPSTSLC-----------FGSASNTNLCFG-------GPPSTSACFSGATSPSFCDGPS 1192

Query: 234  TSSATGLFSSSTTNSGFAYGQNKTA-FGTSTTGFGTNPGGLFGQQNQQTTSLF------S 286
            TS+     +  +TN+GF  G N +A FG    G GT+ G   G     T+S F      S
Sbjct: 1193 TSTGFSFGNGLSTNAGFGGGLNTSAGFGG---GLGTSAGFSGGLS---TSSGFDGGLGTS 1246

Query: 287  KPFGQATTTQNTGFSFGNTSTIG-QPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGT 345
              FG    T +TGF  G  ++ G      T   FG    +  G   G  TN S G+  GT
Sbjct: 1247 AGFGGGPGT-STGFGGGLGTSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGT 1305

Query: 346  GTGLFG--QTNTGFGAVGSTLF------------GNNKLTTFGSSTTSAPSFGTTSGGLF 391
              G  G   T+ GFG+  +  F            G+N  T F    +++  F +    + 
Sbjct: 1306 SAGFSGGLSTSDGFGSRPNASFDRGLSTIIGFGSGSNTSTGFTGEPSTSTGFSSGPSSIV 1365

Query: 392  GFGTNTSGNSIFGSKPAPGTL--GTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFG 449
            GF    S    F S P+      G   GAGFG     G A   G      G   G  + G
Sbjct: 1366 GFSGGPSTGVGFCSGPSTSGFSGGPSTGAGFGGGPNTG-AGFGGGPSTSAGFGSGAASLG 1424

Query: 450  APGFN 454
            A GF+
Sbjct: 1425 ACGFS 1429



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 136/485 (28%), Positives = 190/485 (39%), Gaps = 73/485 (15%)

Query: 5    SFGTPFGGGTGGFGTTS-TFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLF 63
            SFG      T      S +FG       +  G   +S  G  + +    G + +  GG  
Sbjct: 794  SFGCAHSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTL 853

Query: 64   GTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTS 123
             T++      STST FG   +T T  +   + STG     S +  F    P+  G+FG +
Sbjct: 854  STTAGFSGVLSTSTSFGSAPTTSTVFSSALSTSTGFGGILSTSVCFG-GSPSSSGSFGGT 912

Query: 124  TSSGGLFGTTNTTSNPFGST--SGSLFGPSSFTAAPTGTTIKF------NPPTGTDTMVK 175
             S+   FG +  TS  FG T  +   FG SS T+A  G T+        +P TG      
Sbjct: 913  LSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFDGSPSTGAGFGGA 972

Query: 176  AGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATS 235
               S +  +     T      S S +                  G  +T+  FG SP TS
Sbjct: 973  LNTSASFGSVLNTSTGFGGAMSTSAD----------------FGGTLSTSVCFGGSPGTS 1016

Query: 236  SATGLFSSSTTNSGF--AYGQNKTAFGTSTTG--FGTNPGGLFGQQNQQTTSLFSKPFGQ 291
             + G  S+  TN+G+  A   N    GT +T   FG +P    G             FG 
Sbjct: 1017 VSFG--SALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAG-------------FGG 1061

Query: 292  ATTTQNTGFSFG---NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTG 348
            A    NT  SFG   +TS     + +T   F     + PG  FG A +TS G      T 
Sbjct: 1062 AL---NTNASFGCAVSTSASFSGAVSTSACFSGAPITNPG--FGGAFSTSAGFGGALSTA 1116

Query: 349  L-FGQT---NTGFGAVGST--LFGNNKLTT--FGSSTTSAPSFGTTSGGLFGFGTNTSGN 400
              FG T   + GFGA  ST   FG    T+  FG + +++  FG+ S     FG   S +
Sbjct: 1117 ADFGGTPSNSIGFGAAPSTSVSFGGAHGTSLCFGGAPSTSLCFGSASNTNLCFGGPPSTS 1176

Query: 401  SIFGSKPAPG-----TLGTGLGAGFGTALGAGQASLFG---NNQPKIGGPLGTGAFGAPG 452
            + F    +P      +  TG   G G +  AG    FG   N     GG LGT A  + G
Sbjct: 1177 ACFSGATSPSFCDGPSTSTGFSFGNGLSTNAG----FGGGLNTSAGFGGGLGTSAGFSGG 1232

Query: 453  FNTTT 457
             +T++
Sbjct: 1233 LSTSS 1237



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 132/483 (27%), Positives = 187/483 (38%), Gaps = 90/483 (18%)

Query: 24   GQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGT 83
            G +T  G + G +   +  G+ +++GG  G     PG  FG +  +  + S +    FG 
Sbjct: 726  GASTRAGFSDGASISFN--GAPSSSGGFSGG----PGITFGVAPSTSASFSNTASISFGG 779

Query: 84   STGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF---------GTSTSSGGLFGTTN 134
            +  T+++    AS       S + +F+      FG           G S+S  G   T+ 
Sbjct: 780  TLSTSSSFSSAASISFGCAHSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSA 839

Query: 135  T----TSNPFGST-------SGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIS 183
            T     S+ FG T       SG L   +SF +APT +T+ F+    T T     +ST++ 
Sbjct: 840  TFSGGASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTV-FSSALSTSTGFGGILSTSV- 897

Query: 184  TKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAG---TTTGLFGSSPATSSATG- 239
                C        S       L         P    G G   +T+  FG S +TS+  G 
Sbjct: 898  ----CFGGSP--SSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGG 951

Query: 240  -------LFSSSTTNSGFAYGQNKTA-FGT---STTGFG--TNPGGLFGQQNQQTTSLFS 286
                      S +T +GF    N +A FG+   ++TGFG   +    FG     +     
Sbjct: 952  TLSTSICFDGSPSTGAGFGGALNTSASFGSVLNTSTGFGGAMSTSADFGGTLSTSVCFGG 1011

Query: 287  KP-----FGQATTTQNTGFSFG-NTSTIGQPSTNTMGLFGVTQASQPGGLFGTA--TNTS 338
             P     FG A  T N G+    +T+T    + +T   FG + ++  G  FG A  TN S
Sbjct: 1012 SPGTSVSFGSALNT-NAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAG--FGGALNTNAS 1068

Query: 339  TGTAFGTGTGLFGQ------------TNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTT 386
             G A  T     G             TN GFG   ST  G      FG + ++A  FG T
Sbjct: 1069 FGCAVSTSASFSGAVSTSACFSGAPITNPGFGGAFSTSAG------FGGALSTAADFGGT 1122

Query: 387  SGGLFGFGTNTSGNSIFGSKPAPGTLGTGL--GAGFGTALGAGQASLFGNNQPKIGGPLG 444
                 GFG   S +  FG     G  GT L  G    T+L  G AS   N     GGP  
Sbjct: 1123 PSNSIGFGAAPSTSVSFG-----GAHGTSLCFGGAPSTSLCFGSAS---NTNLCFGGPPS 1174

Query: 445  TGA 447
            T A
Sbjct: 1175 TSA 1177



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 77/256 (30%), Positives = 98/256 (38%), Gaps = 25/256 (9%)

Query: 5    SFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG 64
            S G  FG G     T + FG         GG  GTSA  S    GGL   S    GGL  
Sbjct: 1194 STGFSFGNG---LSTNAGFGGGLNTSAGFGGGLGTSAGFS----GGL-STSSGFDGGLGT 1245

Query: 65   TSSFSQ-PATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGN-FGT 122
            ++ F   P TST  G G GTS G +  L  +A  G  L +S           GFG   GT
Sbjct: 1246 SAGFGGGPGTSTGFGGGLGTSAGFSGGLGTSAGFGGGLVTSD----------GFGGGLGT 1295

Query: 123  STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMV--KAGVST 180
            + S G   GT+   S    ++ G    P++       T I F   + T T    +   ST
Sbjct: 1296 NASFGSTLGTSAGFSGGLSTSDGFGSRPNASFDRGLSTIIGFGSGSNTSTGFTGEPSTST 1355

Query: 181  NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVG--AGTTTGL-FGSSPATSSA 237
              S+    I       S  +             GP    G   G  TG  FG  P+TS+ 
Sbjct: 1356 GFSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGGPSTGAGFGGGPNTGAGFGGGPSTSAG 1415

Query: 238  TGLFSSSTTNSGFAYG 253
             G  ++S    GF+YG
Sbjct: 1416 FGSGAASLGACGFSYG 1431



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 42/137 (30%), Positives = 49/137 (35%), Gaps = 39/137 (28%)

Query: 3    NKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTS-----AFGSSNNTG-GLFGNSQ 56
            N SFG+  G   G  G  ST   + GFG+    +F         FGS +NT  G  G   
Sbjct: 1296 NASFGSTLGTSAGFSGGLST---SDGFGSRPNASFDRGLSTIIGFGSGSNTSTGFTGEPS 1352

Query: 57   TKPGGLFGTSSF--------------SQPATS---------------TSTGFGFGTSTGT 87
            T  G   G SS               S P+TS                +TG GFG    T
Sbjct: 1353 TSTGFSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGGPSTGAGFGGGPNTGAGFGGGPST 1412

Query: 88   -ANTLFGTASTGTSLFS 103
             A    G AS G   FS
Sbjct: 1413 SAGFGSGAASLGACGFS 1429


>gi|62122917 filaggrin family member 2 [Homo sapiens]
          Length = 2391

 Score = 93.6 bits (231), Expect = 2e-18
 Identities = 131/486 (26%), Positives = 218/486 (44%), Gaps = 74/486 (15%)

Query: 10   FGGGTG---GFGTT-STFGQNTGFG---TTSG-GAFGTSAFGSSNNTG-GLFGNSQTKPG 60
            +G G+G   GFG   S  GQ++GFG   + SG  ++G  + GSS ++G G  G+ QT   
Sbjct: 583  YGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGF 642

Query: 61   GLFGTSSFSQPATSTSTGFG-FGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPT---- 115
            G  G+ S      S STGFG +G+ +G ++  FG   +G    S Q++ F Q++      
Sbjct: 643  GQHGSGS------SQSTGFGQYGSGSGQSSG-FGQHVSG----SGQSSGFGQHESRSGHS 691

Query: 116  --GFGNFGTSTSSG-GLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDT 172
              G   FG+S SSG G  G+++  ++ FG    S    SSF    +G+       +G   
Sbjct: 692  SYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGS----GQSSGFGQ 747

Query: 173  MVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGL--FGS 230
                   ++   +H+  +    Y   S    +   Y         Q G+  T+G    GS
Sbjct: 748  HGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGY--------GQHGSRQTSGFGQHGS 799

Query: 231  SPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFG 290
              + S+  G + S +  S   +GQ+ +  G S +GFG +      + +Q +         
Sbjct: 800  GSSQSTGFGQYGSGSGQSA-GFGQHGSGSGQS-SGFGQHE----SRSHQSSYGQHGSGSS 853

Query: 291  QATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTA-FGTGTGL 349
            Q++     G S G TS  GQ  +++    G        G  G+ +  S+G    GTG+G 
Sbjct: 854  QSSGYGQHGSSSGQTSGFGQHRSSSGQYSGF-------GQHGSGSGQSSGFGQHGTGSGQ 906

Query: 350  FGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSF---GTTSGGLFGFGTNTSGNSIFGSK 406
            +    +GFG   S     +     GS ++ +  +   G++SG  FGFG + SG+      
Sbjct: 907  Y----SGFGQHESRSH-QSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGF 961

Query: 407  PAPGTLGTGLGAGFGT-ALGAGQASLFGNNQPKIG----GPLGTGAFGAPGF----NTTT 457
               G+ G+G  +GFG    G+G++S FG ++ +      G  G+G+  + G+    +++ 
Sbjct: 962  GQHGS-GSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSG 1020

Query: 458  ATLGFG 463
             T GFG
Sbjct: 1021 QTTGFG 1026



 Score = 87.8 bits (216), Expect = 9e-17
 Identities = 133/493 (26%), Positives = 213/493 (43%), Gaps = 58/493 (11%)

Query: 12  GGTGGFGTT-STFGQNTGFGTTSGGAFGTSAFGSSNNTGGL---FGNSQTKPGGLFGTSS 67
           G T GFG   S  GQ++GFG    G+  +S FG   +  G    FG   +  G   G   
Sbjct: 474 GKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQ 533

Query: 68  FSQPATSTSTG-FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTST-- 124
               +  +S G  G G+S  +    +G+  T         +     + TGFG +G+ +  
Sbjct: 534 HESRSRQSSYGQHGSGSSQSSGYGQYGSRETS----GFGQHGLGSGQSTGFGQYGSGSGQ 589

Query: 125 SSG-GLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIS 183
           SSG G  G+ +  S+ FG    S  G SS+    +G++ + +      +   +G   + S
Sbjct: 590 SSGFGQHGSGSGQSSGFGQHE-SRSGQSSYGQHSSGSS-QSSGYGQHGSRQTSGFGQHGS 647

Query: 184 TKHQCITAMKEYESKSLEELRLEDY-----QANRKGPQNQVGAGTTTGLFGSSPATSSAT 238
              Q  T   +Y S S +      +     Q++  G        ++ G  G   + SS  
Sbjct: 648 GSSQS-TGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGY 706

Query: 239 GLF-SSSTTNSGFAYGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQAT 293
           G   SSS   SGF  GQ++ + G S++    G G+     FGQ    +    S  FGQ  
Sbjct: 707 GQHGSSSGQTSGF--GQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQ--SSGFGQHE 762

Query: 294 TTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTA-FGTGTGL--- 349
           +      S+G  S+ G   ++  G  G  Q S   G  G+ ++ STG   +G+G+G    
Sbjct: 763 SRSGQS-SYGQHSS-GSSQSSGYGQHGSRQTS-GFGQHGSGSSQSTGFGQYGSGSGQSAG 819

Query: 350 FGQTNTGFGAVGSTLFGNNKLTTF---------GSSTTSA-PSFGTTSGGLFGFGTNTSG 399
           FGQ  +G G   S+ FG ++  +          GSS +S     G++SG   GFG + S 
Sbjct: 820 FGQHGSGSGQ--SSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSS 877

Query: 400 NSIFGSKPAPGTLGTGLGAGFGT-ALGAGQASLFGNNQPKIG----GPLGTGAFGAPGF- 453
           +  +      G+ G+G  +GFG    G+GQ S FG ++ +      G  G+G+  + G+ 
Sbjct: 878 SGQYSGFGQHGS-GSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYG 936

Query: 454 ---NTTTATLGFG 463
              +++  T GFG
Sbjct: 937 QHGSSSGQTFGFG 949



 Score = 74.7 bits (182), Expect = 8e-13
 Identities = 128/535 (23%), Positives = 212/535 (39%), Gaps = 83/535 (15%)

Query: 13  GTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72
           G+GG        Q+   G    G+ G  +  SS+N    F        G   ++SF Q  
Sbjct: 384 GSGG-------SQSCSNGQHEYGSCGRFSNSSSSNE---FSKCDQYGSGSSQSTSFEQHG 433

Query: 73  TSTSTGFGFGTST-GTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFG 131
           T  S   GF     G+  T     ST +       +  +  K +GFG  G+ +     FG
Sbjct: 434 TGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFG 493

Query: 132 TTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191
              + S   G +SG  FG     +  +    +    +G  +    G   + S   Q  ++
Sbjct: 494 QCGSGS---GQSSG--FGQHGSVSGQSSGFGQHGSVSGQSS----GFGQHESRSRQ--SS 542

Query: 192 MKEYESKSLEELRLEDYQANRKGP--QNQVGAGTTTGL--FGSSPATSSATGLFSSSTTN 247
             ++ S S +      Y +       Q+ +G+G +TG   +GS    SS  G   S +  
Sbjct: 543 YGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQ 602

Query: 248 SGFAYGQNKTAFGTSTTG---FGTNPGGLFGQQNQQTTSLFSKPFGQ--ATTTQNTGFS- 301
           S   +GQ+++  G S+ G    G++    +GQ   + TS     FGQ  + ++Q+TGF  
Sbjct: 603 SS-GFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTS----GFGQHGSGSSQSTGFGQ 657

Query: 302 FGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVG 361
           +G+ S  GQ S     + G  Q+S     FG   + S  +++G   G     ++G+G  G
Sbjct: 658 YGSGS--GQSSGFGQHVSGSGQSSG----FGQHESRSGHSSYGQH-GFGSSQSSGYGQHG 710

Query: 362 STL-----FGNNKLTT--------FGSSTTSAPSFG---TTSGGLFGFGTNTS--GNSIF 403
           S+      FG ++L++         GS +  +  FG   + SG   GFG + S  G S +
Sbjct: 711 SSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSY 770

Query: 404 GSKPAPGTLGTGLG-------AGFGT--------------ALGAGQASLFGNNQPKIGGP 442
           G   +  +  +G G       +GFG                 G+GQ++ FG +    G  
Sbjct: 771 GQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQS 830

Query: 443 LGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFG 497
            G G   +    ++    G G+ Q+       ++S       Q   +S  YS FG
Sbjct: 831 SGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFG 885



 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 113/481 (23%), Positives = 192/481 (39%), Gaps = 82/481 (17%)

Query: 3    NKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGL 62
            ++S  + +G    G   +S +GQ+   G++SG    TS FG   ++ G +          
Sbjct: 838  SRSHQSSYGQHGSGSSQSSGYGQH---GSSSGQ---TSGFGQHRSSSGQY---------- 881

Query: 63   FGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGT 122
               S F Q       G G G S+G     FG   TG+  +S      +++  + +G  G+
Sbjct: 882  ---SGFGQ------HGSGSGQSSG-----FGQHGTGSGQYSGFGQHESRSHQSSYGQHGS 927

Query: 123  STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182
             +S    +G         GS+SG  FG     +  +G +  F    G+ +   +G   + 
Sbjct: 928  GSSQSSGYG-------QHGSSSGQTFGFGQHRSG-SGQSSGFG-QHGSGSGQSSGFGQHE 978

Query: 183  STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLF- 241
            S   +  +   ++ES+S +     +Y  +  G     G G      GSS   ++  G   
Sbjct: 979  SGSGKS-SGFGQHESRSSQ----SNYGQHGSGSSQSSGYGQ----HGSSSGQTTGFGQHR 1029

Query: 242  SSSTTNSGFAY----GQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQ--ATTT 295
            SSS   SGF          + FG   TG G + G  FGQ   ++       +GQ  + ++
Sbjct: 1030 SSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSG--FGQYESRSR---QSSYGQHGSGSS 1084

Query: 296  QNTGF-----SFGNTSTIGQ-----PSTNTMGLFGVTQASQPG-GLFGTATNTSTGTA-- 342
            Q++G+     + G TS  GQ       ++  G +G       G G  G+ T  S+G A  
Sbjct: 1085 QSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQH 1144

Query: 343  -FGTGTGLFGQTNTG---FGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTS 398
             + +G   +GQ  TG       G    G+   T+FG   + + +F ++   +   G +T 
Sbjct: 1145 EYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTG 1204

Query: 399  GNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTA 458
                FG   +     TGLG G    + +G +++ G  +   G  + T      G   +T 
Sbjct: 1205 ----FGQYGSGSGQSTGLGQGESQQVESG-STVHGRQETTHGQTINTTRHSQSGQGQSTQ 1259

Query: 459  T 459
            T
Sbjct: 1260 T 1260



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 110/440 (25%), Positives = 180/440 (40%), Gaps = 60/440 (13%)

Query: 69  SQPATSTSTGFGFGT-STGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSG 127
           S P + + +  G+G    G      G   TG    SSQ++   Q     +G+ G+ + S 
Sbjct: 343 SNPCSQSYSQRGYGARENGQPQNCGGQWRTG----SSQSSCCGQ-----YGSGGSQSCSN 393

Query: 128 GL--FGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTK 185
           G   +G+    SN   S+S + F       + +  +  F    GT     +G   ++   
Sbjct: 394 GQHEYGSCGRFSN---SSSSNEFSKCDQYGSGSSQSTSFEQH-GTGLSQSSGFEQHVCGS 449

Query: 186 HQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSST 245
            Q      ++ES S + L  + + ++        G  +  G  GS    SS  G   S +
Sbjct: 450 GQ---TCGQHESTSSQSLGYDQHGSSS-------GKTSGFGQHGSGSGQSSGFGQCGSGS 499

Query: 246 TNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNT 305
             S   +GQ+ +  G S+ GFG + G + GQ         S  FGQ  +      S+G  
Sbjct: 500 GQSS-GFGQHGSVSGQSS-GFGQH-GSVSGQ---------SSGFGQHESRSRQS-SYGQH 546

Query: 306 STIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTA-FGTGTGLFGQTNTGFGAVGSTL 364
            + G   ++  G +G  + S   G  G  +  STG   +G+G+G     ++GFG  GS  
Sbjct: 547 GS-GSSQSSGYGQYGSRETSG-FGQHGLGSGQSTGFGQYGSGSG----QSSGFGQHGS-- 598

Query: 365 FGNNKLTTFGS--STTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGA---- 418
            G+ + + FG   S +   S+G  S G     + +SG    GS+   G    G G+    
Sbjct: 599 -GSGQSSGFGQHESRSGQSSYGQHSSG----SSQSSGYGQHGSRQTSGFGQHGSGSSQST 653

Query: 419 GFGT-ALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNAS 477
           GFG    G+GQ+S FG +    G   G G   +   +++    GFG+ Q+       ++S
Sbjct: 654 GFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSS 713

Query: 478 AAQQAVLQQHINSLTYSPFG 497
                  Q  ++S   S FG
Sbjct: 714 GQTSGFGQHELSSGQSSSFG 733



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 91/401 (22%), Positives = 154/401 (38%), Gaps = 44/401 (10%)

Query: 7    GTPFGGGTGGFGTTSTFGQNTGFGTTSG----GAFGTSAFGSSNNTGGLFGNSQTKPGGL 62
            G+    G G  GT S  GQ++GFG         ++G    GSS ++G  +G   +  G  
Sbjct: 1044 GSDQSSGFGQHGTGS--GQSSGFGQYESRSRQSSYGQHGSGSSQSSG--YGQHGSNSGQ- 1098

Query: 63   FGTSSFSQ--PATSTSTGFG-FGTSTGTANTLFGTASTGTSLFSSQNNAFAQNK----PT 115
              TS F Q  P +  S+GFG +G+ +G ++  FG   +GT     +++ FAQ++     +
Sbjct: 1099 --TSGFGQHRPGSGQSSGFGQYGSGSGQSSG-FGQHGSGT----GKSSGFAQHEYRSGQS 1151

Query: 116  GFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTA-----APTGTTI---KFNPP 167
             +G  GT +S     G   + S P  S    + G  +F++     + +G +    ++   
Sbjct: 1152 SYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSG 1211

Query: 168  TGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGL 227
            +G  T +  G S  + +     T     E+   + +    +  + +G   Q G+  T   
Sbjct: 1212 SGQSTGLGQGESQQVESGS---TVHGRQETTHGQTINTTRHSQSGQGQSTQTGSRVTRRR 1268

Query: 228  FGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSK 287
              S    S +      S  +S   + Q  + +  S +      G   GQ+   T    S 
Sbjct: 1269 RSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHS- 1327

Query: 288  PFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVT----QASQPGGLFGTATNTSTGTAF 343
              G   +TQ    + G        +T++    GV+       Q     G+    S  T  
Sbjct: 1328 --GHGQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVH 1385

Query: 344  GTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFG 384
                  +GQT     A G    G+ + T  GS TT     G
Sbjct: 1386 ERHETTYGQTGE---ATGHGHSGHGQSTQRGSRTTGRRGSG 1423



 Score = 38.5 bits (88), Expect = 0.060
 Identities = 43/170 (25%), Positives = 65/170 (38%), Gaps = 12/170 (7%)

Query: 214  GPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGL 273
            G   Q G+ TT          S + G    S T+SG  +GQ ++  G S +      G +
Sbjct: 1711 GLTTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERHGTI 1770

Query: 274  FGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGT 333
             GQ    T    S   G   +TQ    + G  S+     +++ G  G +Q     G    
Sbjct: 1771 HGQTGDTTRHAHS---GHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRG---- 1823

Query: 334  ATNTSTGTAFGTGTGLFGQTN-TGFGAVGST----LFGNNKLTTFGSSTT 378
             T+   G+  G    +  + + T  G  G T      G+ + T  GSSTT
Sbjct: 1824 HTHGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTT 1873



 Score = 37.7 bits (86), Expect = 0.10
 Identities = 100/424 (23%), Positives = 158/424 (37%), Gaps = 65/424 (15%)

Query: 7    GTPFGGGTGGFGTTSTFGQNTGFG--TTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG 64
            G P  G T   G+ +T  + +G    + S G  G S    S +T G  G+   + G    
Sbjct: 1933 GHPSHGQTIQTGSRTTGRRGSGHSEYSDSEGPSGVS-HTHSGHTHGQAGSHYPESGSSVH 1991

Query: 65   T---SSFSQPATSTSTGF-GFGTSTGTANTLFGTASTGTSLFS-SQNNAFAQNKPTGFGN 119
                ++  Q A +T  G  G G ST   +   G  ++G S +S S+ ++   +  +G  +
Sbjct: 1992 ERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAH 2051

Query: 120  ------FGTSTSS-----GGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPT 168
                   G S SS     G   G T  T+    S  G      S TA   G+        
Sbjct: 2052 GQAGSQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGS----GHSE 2107

Query: 169  GTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELR----------LEDYQANRKGPQNQ 218
             +D+ V +GVS   S         +  ES S    R             +  +  G   Q
Sbjct: 2108 SSDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQ 2167

Query: 219  VGAGTTTGLFGSSPATSSATGLFS-SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQ 277
             G+  TTG   SS + SS + + S +S T+SG  + Q  +  G S    G++  G  G  
Sbjct: 2168 TGS-RTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQS----GSSGHGRQGTT 2222

Query: 278  NQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNT 337
            + QT            TT++  + +G ++  G  +T   G      +      +G+ T++
Sbjct: 2223 HGQT----------GDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWGSHTHS 2272

Query: 338  STGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNT 397
                       + GQ  +     GST+ G          TT   +  TT  G  G+G +T
Sbjct: 2273 G---------HIQGQAGSQQRQPGSTVHGR-------LETTHGQTGDTTRHGHSGYGQST 2316

Query: 398  SGNS 401
               S
Sbjct: 2317 QTGS 2320



 Score = 32.0 bits (71), Expect = 5.6
 Identities = 47/173 (27%), Positives = 68/173 (39%), Gaps = 18/173 (10%)

Query: 214  GPQNQVGAGTTTGLFGSSPATSSATGLFSS-STTNSGFAYGQNKTAFGTSTTGFGTNPGG 272
            G   Q G+ +TTG  GS  + SS + + S  S T+SG  +GQ+ +  G S +        
Sbjct: 1484 GKSTQRGS-STTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESESIIHDRHRI 1542

Query: 273  LFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNT-MGLFGVTQASQPGGLF 331
              GQ    T   +S   G   TTQ    + G   T    ST++ +   G  +       +
Sbjct: 1543 THGQTGDTTRHSYS---GHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREHTY 1599

Query: 332  GTATNTSTGTAF------GTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTT 378
            G A +      F      GT  G  G T       G +  G+ + T  GS TT
Sbjct: 1600 GQAGSQHEEPEFTVHERHGTTHGQIGDT------TGHSHSGHGQSTQRGSRTT 1646


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 112/461 (24%), Positives = 185/461 (40%), Gaps = 31/461 (6%)

Query: 20  TSTFGQNTGFGTTSGGAF-----GTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATS 74
           TST   NTG    S GA      G+S   S  +T  + G+S T  G    T+S     +S
Sbjct: 27  TST-SANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSS 85

Query: 75  TSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTN 134
                  G ST T N+ F T S+G S+ ++  ++   +  +   N  +ST S G    TN
Sbjct: 86  -------GISTAT-NSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATN 137

Query: 135 TTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKE 194
           + S+   S + +     S T +   +T   N  + T T   A  +TN  +      A   
Sbjct: 138 SDSSTTSSGASTATNSDSSTTSSEASTAT-NSESST-TSSGASTATNSESSTVSSRASTA 195

Query: 195 YESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQ 254
             S+S           N +      GAGT T    S+ ++ ++T   S S+T S  A   
Sbjct: 196 TNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTA 255

Query: 255 NKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTN 314
             +   T+++G GT         N +++++ S       +  +T  S  NT+T  + ST 
Sbjct: 256 TNSESSTTSSGAGT-------ATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTT 308

Query: 315 TMGLFGVTQASQPGGLFG--TATNT-STGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLT 371
           + G    T +       G  TATN+ S+ T+ G  T    +++T      +     +  T
Sbjct: 309 SSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTT 368

Query: 372 TFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALG--AGQA 429
           + G+ST +     T S G     T+ S  +  G+  A  +  + + +G  TA    +   
Sbjct: 369 SSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTT 428

Query: 430 SLFGNNQPKIGGPL---GTGAFGAPGFNTTTATLGFGAPQA 467
           S   N     G  +   G+G     G +TT+ +      +A
Sbjct: 429 SSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEA 469



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 104/434 (23%), Positives = 164/434 (37%), Gaps = 79/434 (18%)

Query: 3   NKSFGTPFGG---GTGGFGTTSTFGQNTGFGT-----TSGGAFGTSAFGSSNNTGGLFGN 54
           N  F T   G    T    +T++ G +T   +     +SG +  T++  S+ ++G    +
Sbjct: 92  NSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGA---S 148

Query: 55  SQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGT---ANTLFGTASTGTSLFSSQNNAFAQ 111
           + T       +S  S    S S+    G ST T   ++T+   AST T+  SS  ++ A 
Sbjct: 149 TATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGAS 208

Query: 112 NKP------------TGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTG 159
                          T   +  ++TSSG    T + +S P      +    SS T++  G
Sbjct: 209 TATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAG 268

Query: 160 TTIKFNPPT---GTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQ 216
           T       T   G  T+  +  ST  S  +    +     S         D      G  
Sbjct: 269 TATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGAS 328

Query: 217 NQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQ 276
               + ++T   G+S AT+S      SSTT+SG +   N    G+STT  GT+       
Sbjct: 329 TATNSESSTTSSGASTATNS-----ESSTTSSGASTATNS---GSSTTSSGTSTA----- 375

Query: 277 QNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATN 336
            N +++++ S      T+  +T  S  +T+T  + ST + G               TATN
Sbjct: 376 TNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGA-------------STATN 422

Query: 337 TSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTN 396
           + + T                     T  G N  T  GSS TSA   G+ +  L G  T 
Sbjct: 423 SESST---------------------TSSGANTATNSGSSVTSA---GSGTAALTGMHTT 458

Query: 397 TSGNSIFGSKPAPG 410
           +   S   S+  PG
Sbjct: 459 SHSASTAVSEAKPG 472



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 65/270 (24%), Positives = 113/270 (41%), Gaps = 54/270 (20%)

Query: 3   NKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGL 62
           ++S  T  G GT     +ST   ++G  T +     T + G++  T     +S T  G  
Sbjct: 258 SESSTTSSGAGTATNSESSTV--SSGISTVTNSESSTPSSGANTATNS--ESSTTSSGAN 313

Query: 63  FGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGT 122
             T+S S   ++TS+G    T++ ++ T  G AST T+  SS  ++ A        N G+
Sbjct: 314 TATNSDS---STTSSGASTATNSESSTTSSG-ASTATNSESSTTSSGASTAT----NSGS 365

Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182
           ST+S G    T+T +N   ST  S  G S+ T + + TT              +G ST  
Sbjct: 366 STTSSG----TSTATNSESSTVSS--GASTATTSESSTT-------------SSGASTAT 406

Query: 183 STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFS 242
           +++   +++                      G      + ++T   G++ AT+S + + S
Sbjct: 407 NSESSTVSS----------------------GASTATNSESSTTSSGANTATNSGSSVTS 444

Query: 243 SSTTNSGFAYGQNKTAFGTSTTGFGTNPGG 272
           + +  +    G + T+   ST      PGG
Sbjct: 445 AGSGTAALT-GMHTTSHSASTAVSEAKPGG 473


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 140/563 (24%), Positives = 218/563 (38%), Gaps = 73/563 (12%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTS 76
            TTST G  T   +T G    T++  SS  T      S+T      G  T++ S   + T+
Sbjct: 845  TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 77   TGFGFG------TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF-----GTSTS 125
            T    G      ++TG+  T   T  + T+  S++ +       TG         G+ T+
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 126  SGGLFGTTNTTSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIS 183
            +    G+  TT++  GS  T+ S  G  + TA+  G+       TG++T   +   T  +
Sbjct: 965  TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024

Query: 184  TKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSS 243
                 IT+ +  E+ ++     E       G +      TTT   GS   T S TG   S
Sbjct: 1025 -----ITSTEGSETTTVTTAGSETTAVYTTGSET-----TTTSTEGSETTTVSTTG---S 1071

Query: 244  STTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFG 303
             TT +  A  +  T    ST+G GT      G    +TT+++    G  TTT +T  S  
Sbjct: 1072 ETTTASTADLETTT---VSTSGSGTTTASTAG---SETTTVYIT--GSKTTTASTEGSEA 1123

Query: 304  NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363
             T +     T T      T  S+   +F T + T+T +  G+       T++  G+  +T
Sbjct: 1124 TTVSTTSSETTTAS----TTGSEMTTVFTTVSETTTVSTIGSE----ATTSSAAGSEATT 1175

Query: 364  LFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTA 423
                   +T GS TT+A + G+ +      G+ T+  S  GS+    T  +  G+   TA
Sbjct: 1176 ------TSTEGSETTTASTAGSETTTASTAGSETTTASTAGSET---TTASTSGSETNTA 1226

Query: 424  LGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTT---------TATLGFGAPQAPVALTDP 474
               G  +    + P   G     AF   G  TT         TAT   G+    V++T  
Sbjct: 1227 CTTGSET----STPSSAGSETNTAF-IIGSETTIASTASLEPTATSLTGSETTTVSITAS 1281

Query: 475  NASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYK 534
             A+AA   V          +     P+   PMS  +    RL      A  ++T      
Sbjct: 1282 GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRL-----TASSSVTMAPGMD 1336

Query: 535  LTPRPATRVRPK-ALQTTGTAKS 556
             T   A+   P   L T+G   S
Sbjct: 1337 FTASAASHTVPGIVLNTSGLGTS 1359



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 121/505 (23%), Positives = 182/505 (36%), Gaps = 66/505 (13%)

Query: 18   GTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77
            G+  T    TG  TT+    G+    +S     L   S T       T + S   + T+T
Sbjct: 910  GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS----ETITVSAEGSETTT 965

Query: 78   GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNTT 136
                G+ T TA+T     +T ++  S    A  + ++ T   + G+ T++    GT  T 
Sbjct: 966  VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTI 1025

Query: 137  SNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196
            ++  GS +      ++ T A + TT  +   TG++T      ST  S      T   E  
Sbjct: 1026 TSTEGSET------TTVTTAGSETTAVYT--TGSETTT---TSTEGSETTTVSTTGSETT 1074

Query: 197  SKSLEELRLEDYQANRKGPQNQVGAG---TTTGLFGSSPATSSATG-------LFSSSTT 246
            + S  +L       +  G      AG   TT  + GS   T+S  G         SS TT
Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 247  NSGFAYGQNKTAFGT-------STTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTG 299
             +     +  T F T       ST G         G +   T++      G  TTT +T 
Sbjct: 1135 TASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTST-----EGSETTTASTA 1189

Query: 300  FSFGNTSTIGQPSTNTMGLFG--VTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGF 357
             S   T++     T T    G   T AS  G    TA  T + T+  +  G   +TNT F
Sbjct: 1190 GSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAG--SETNTAF 1247

Query: 358  GAVGS--------------TLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSI- 402
              +GS              T    ++ TT   + + A +  TT        T  +  SI 
Sbjct: 1248 -IIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQ 1306

Query: 403  -FGSKPAPG--TLGTGLGAGFGTALGAGQ---ASLFGNNQPKIGGPLGTGAFGAPGFNTT 456
               + P  G  T GT L A     +  G    AS   +  P  G  L T   G      +
Sbjct: 1307 PITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVP--GIVLNTSGLGTSTMGAS 1364

Query: 457  TATLGFGAPQAPVALTDPNASAAQQ 481
            + T   G      +  +P +S  Q+
Sbjct: 1365 STTSAHGVRTTTGSTREPTSSTFQE 1389



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 89/396 (22%), Positives = 145/396 (36%), Gaps = 38/396 (9%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
           T S  G  T   + SG    T++   S NT      S T    + G+ +    A S +T 
Sbjct: 47  TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT 106

Query: 79  FGFGTSTGTANTLFGTASTGTSLFSSQNN--AFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136
                +  T  +  G+ +T  S  SS+    + A ++ T     G+ T++     +  T 
Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166

Query: 137 SNPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191
           ++  GS   ++F   S T  P+      TT+       T        +T  ST H   TA
Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTA 226

Query: 192 MKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251
                S++ +               +  G+ TT    GS    +S       S TN+ F 
Sbjct: 227 ASTMGSETTKV--------------STAGSETTVSTAGSETTAAST----EDSETNTAFT 268

Query: 252 YGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQP 311
                T    STTGF T      G +    +++     G  TT  +T      T+ +   
Sbjct: 269 EDSKTTT--ASTTGFETTAASTTGSEPTMASTM-----GSETTMAST--IGPETTKVSTA 319

Query: 312 STNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGT-GLFGQTNTGFGAVGSTLFGNNKL 370
           S+    +F     +      G+ T T + T   T T  + G   +     GS        
Sbjct: 320 SSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE---TTTA 376

Query: 371 TTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
           +T GS TT+A + G+ +  +   G+ T+  SI  S+
Sbjct: 377 STEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 94/395 (23%), Positives = 157/395 (39%), Gaps = 39/395 (9%)

Query: 18  GTTSTFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72
           G+ +T    TG  TT+    G+     S  GS   T    G+  T       ++  S+  
Sbjct: 340 GSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTT-----ASTEGSEAT 394

Query: 73  TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132
           T ++TG    T + T +    T + G+ + +     F     +  G+  T  S+     T
Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454

Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192
           T +T     +T+ +  G  + TA  TG+       TG +T     + ++ +T      + 
Sbjct: 455 TASTEGS-ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-----AST 508

Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252
           +  E+ ++     E    + +G +N     TT    GS   T S TGL +++T+  G   
Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSEN-----TTVSTTGSETTTVSTTGLETTTTSTEGSEM 563

Query: 253 GQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPS 312
               T  G  TT   T   G        TT+  +   G  TTT +T  S   T++     
Sbjct: 564 TTVSTT-GAETTTDSTEGSG--------TTA--ASTAGSETTTVSTADSENTTASTADSE 612

Query: 313 TNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTT 372
           T +      T  S+      T++ T+T +  G+ T     T++    V +T       +T
Sbjct: 613 TTSAS----TTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITST 668

Query: 373 FGSSTTSAPSFGT-TSGGLFGFGTNTSGNSIFGSK 406
            GS TT+  + G+ T+    G GT T   SI GS+
Sbjct: 669 EGSETTTVSATGSETTVSTEGSGTTTV--SITGSE 701



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 99/409 (24%), Positives = 158/409 (38%), Gaps = 41/409 (10%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG------------GLFGTS 66
           T ST G  T   +T G    T +   S  T     +S+T                +F T+
Sbjct: 375 TASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETT 434

Query: 67  SFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTS 125
           + S   +  +      + T TA+T     +T T+  S    A+   ++ T   N G  T+
Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494

Query: 126 SGGLFGTTNTTSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGV---ST 180
           +    G+  TT++  GS  T+ S  G    T +  G+       TG++T   +     +T
Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240
             ST+   +T +    S +  E   +  + +     +  G+ TTT     S  T+++T  
Sbjct: 555 TTSTEGSEMTTV----STTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTA- 609

Query: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300
             S TT++     +  TA   STT   T      G +    T+  S    + T    TG 
Sbjct: 610 -DSETTSASTTGSETTTA---STTSSETTTASTEGSE----TTTVSTTDSETTMVSTTGS 661

Query: 301 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGT----AFGTGTGLFGQTNTG 356
               TST G  +T        T  S  G   GT T + TG+       TG+     +  G
Sbjct: 662 ERTITSTEGSETTTVSATGSETTVSTEGS--GTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 357 FGAVGSTLFGNNKLT--TFGSSTTSAPSFG--TTSGGLFGFGTNTSGNS 401
                +++ G+   T  T GS TT+A + G  TTS    G  T T+  +
Sbjct: 720 SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 91/400 (22%), Positives = 152/400 (38%), Gaps = 24/400 (6%)

Query: 19  TTSTFGQNTGFGTTSGG-AFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77
           T  T G +T   +T G      SA GS   T    G+  T       +++ S+  T ++T
Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTV-----STTGSETTTVSTT 549

Query: 78  GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTS 137
           G    T++   + +   ++TG    +           +  G+  T+ S+     TT +T+
Sbjct: 550 GLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTA 609

Query: 138 NPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYES 197
           +   +TS S  G  + TA+ T +        G++T     VST  S      T   E   
Sbjct: 610 DS-ETTSASTTGSETTTASTTSSETTTASTEGSETTT---VSTTDSETTMVSTTGSERTI 665

Query: 198 KSLEELRLEDYQANRKGPQNQV---GAGTTT-GLFGSSPATSSATGLFSSSTTNSGFAYG 253
            S E        A   G +  V   G+GTTT  + GS     S TG  +++T+  G    
Sbjct: 666 TSTEGSETTTVSAT--GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI- 722

Query: 254 QNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPST 313
              +  G+ TT   T          + + +  +   G  TTT +T  S    ++I    T
Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSET 782

Query: 314 NTMGLFG--VTQASQPGGLFGT--ATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNK 369
                 G   T+ S       T    N+ T  A  T +     +  G   + ++  G+  
Sbjct: 783 TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 370 LTTF---GSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
            TT    GS TT+A + G+ +       + T+  +  GS+
Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 77/327 (23%), Positives = 131/327 (40%), Gaps = 38/327 (11%)

Query: 71  PATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGF--------GNFGT 122
           PA  ++T     T + T   L   + T T+  S+  +      PTG         G+  T
Sbjct: 9   PAAGSNTTTASTTGSETTTILIKASETTTA--STAGSETTTPSPTGSQTTIVSISGSEIT 66

Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182
           +TS+ G   TT +++   G+T+ S+ G S  T +  G+       TGT+T + + + +  
Sbjct: 67  TTSTAGSENTTVSSAGS-GTTTASMAG-SETTVSTAGSETTTVSITGTETTMVSAMGSET 124

Query: 183 STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFS 242
           +T            S +  E  +     +     + VG+ TTT     S  T+++T    
Sbjct: 125 TT-----------NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSE 173

Query: 243 SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302
            +T  +  +     +  G+ TT   T           +TT++ +   G  TTT +T  S 
Sbjct: 174 MTTVFTAGSETITPSTAGSETTTVST--------AGSETTTVSTT--GSETTTASTAHSE 223

Query: 303 GN-TSTIGQPSTNTMGLFGVTQASQPGGLFGTAT--NTSTGTAFGTGTGLFGQTNTGFGA 359
               ST+G  +T        T  S  G     A+  ++ T TAF   +     + TGF  
Sbjct: 224 TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFET 283

Query: 360 VGSTLFGN--NKLTTFGSSTTSAPSFG 384
             ++  G+     +T GS TT A + G
Sbjct: 284 TAASTTGSEPTMASTMGSETTMASTIG 310



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 68/286 (23%), Positives = 102/286 (35%), Gaps = 48/286 (16%)

Query: 131 GTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC 188
           G+  TT++  GS + ++   +S   TA+  G+      PTG+ T + +   + I+T    
Sbjct: 12  GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTS-- 69

Query: 189 ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248
            TA  E  + S                    G+GTTT     S  T S  G  S +TT  
Sbjct: 70  -TAGSENTTVS------------------SAGSGTTTASMAGSETTVSTAG--SETTT-- 106

Query: 249 GFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTI 308
                        S TG  T      G +    T+  S    + T T   G      ST+
Sbjct: 107 ------------VSITGTETTMVSAMGSE----TTTNSTTSSETTVTSTAGSETTTVSTV 150

Query: 309 GQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNN 368
           G  +T        T A+   G   T   T+        T   G   T     GS      
Sbjct: 151 GSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTA--GSETTTVSTAGSE---TT 205

Query: 369 KLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGT 414
            ++T GS TT+A +  + +      G+ T+  S  GS+    T G+
Sbjct: 206 TVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS 251


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 140/563 (24%), Positives = 218/563 (38%), Gaps = 73/563 (12%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTS 76
            TTST G  T   +T G    T++  SS  T      S+T      G  T++ S   + T+
Sbjct: 845  TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 77   TGFGFG------TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF-----GTSTS 125
            T    G      ++TG+  T   T  + T+  S++ +       TG         G+ T+
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 126  SGGLFGTTNTTSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIS 183
            +    G+  TT++  GS  T+ S  G  + TA+  G+       TG++T   +   T  +
Sbjct: 965  TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024

Query: 184  TKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSS 243
                 IT+ +  E+ ++     E       G +      TTT   GS   T S TG   S
Sbjct: 1025 -----ITSTEGSETTTVTTAGSETTAVYTTGSET-----TTTSTEGSETTTVSTTG---S 1071

Query: 244  STTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFG 303
             TT +  A  +  T    ST+G GT      G    +TT+++    G  TTT +T  S  
Sbjct: 1072 ETTTASTADLETTT---VSTSGSGTTTASTAG---SETTTVYIT--GSKTTTASTEGSEA 1123

Query: 304  NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363
             T +     T T      T  S+   +F T + T+T +  G+       T++  G+  +T
Sbjct: 1124 TTVSTTSSETTTAS----TTGSEMTTVFTTVSETTTVSTIGSE----ATTSSAAGSEATT 1175

Query: 364  LFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTA 423
                   +T GS TT+A + G+ +      G+ T+  S  GS+    T  +  G+   TA
Sbjct: 1176 ------TSTEGSETTTASTAGSETTTASTAGSETTTASTAGSET---TTASTSGSETNTA 1226

Query: 424  LGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTT---------TATLGFGAPQAPVALTDP 474
               G  +    + P   G     AF   G  TT         TAT   G+    V++T  
Sbjct: 1227 CTTGSET----STPSSAGSETNTAF-IIGSETTIASTASLEPTATSLTGSETTTVSITAS 1281

Query: 475  NASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYK 534
             A+AA   V          +     P+   PMS  +    RL      A  ++T      
Sbjct: 1282 GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRL-----TASSSVTMAPGMD 1336

Query: 535  LTPRPATRVRPK-ALQTTGTAKS 556
             T   A+   P   L T+G   S
Sbjct: 1337 FTASAASHTVPGIVLNTSGLGTS 1359



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 121/505 (23%), Positives = 182/505 (36%), Gaps = 66/505 (13%)

Query: 18   GTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77
            G+  T    TG  TT+    G+    +S     L   S T       T + S   + T+T
Sbjct: 910  GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS----ETITVSAEGSETTT 965

Query: 78   GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNTT 136
                G+ T TA+T     +T ++  S    A  + ++ T   + G+ T++    GT  T 
Sbjct: 966  VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTI 1025

Query: 137  SNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196
            ++  GS +      ++ T A + TT  +   TG++T      ST  S      T   E  
Sbjct: 1026 TSTEGSET------TTVTTAGSETTAVYT--TGSETTT---TSTEGSETTTVSTTGSETT 1074

Query: 197  SKSLEELRLEDYQANRKGPQNQVGAG---TTTGLFGSSPATSSATG-------LFSSSTT 246
            + S  +L       +  G      AG   TT  + GS   T+S  G         SS TT
Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 247  NSGFAYGQNKTAFGT-------STTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTG 299
             +     +  T F T       ST G         G +   T++      G  TTT +T 
Sbjct: 1135 TASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTST-----EGSETTTASTA 1189

Query: 300  FSFGNTSTIGQPSTNTMGLFG--VTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGF 357
             S   T++     T T    G   T AS  G    TA  T + T+  +  G   +TNT F
Sbjct: 1190 GSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAG--SETNTAF 1247

Query: 358  GAVGS--------------TLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSI- 402
              +GS              T    ++ TT   + + A +  TT        T  +  SI 
Sbjct: 1248 -IIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQ 1306

Query: 403  -FGSKPAPG--TLGTGLGAGFGTALGAGQ---ASLFGNNQPKIGGPLGTGAFGAPGFNTT 456
               + P  G  T GT L A     +  G    AS   +  P  G  L T   G      +
Sbjct: 1307 PITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVP--GIVLNTSGLGTSTMGAS 1364

Query: 457  TATLGFGAPQAPVALTDPNASAAQQ 481
            + T   G      +  +P +S  Q+
Sbjct: 1365 STTSAHGVRTTTGSTREPTSSTFQE 1389



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 89/396 (22%), Positives = 145/396 (36%), Gaps = 38/396 (9%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
           T S  G  T   + SG    T++   S NT      S T    + G+ +    A S +T 
Sbjct: 47  TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT 106

Query: 79  FGFGTSTGTANTLFGTASTGTSLFSSQNN--AFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136
                +  T  +  G+ +T  S  SS+    + A ++ T     G+ T++     +  T 
Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166

Query: 137 SNPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191
           ++  GS   ++F   S T  P+      TT+       T        +T  ST H   TA
Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTA 226

Query: 192 MKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251
                S++ +               +  G+ TT    GS    +S       S TN+ F 
Sbjct: 227 ASTMGSETTKV--------------STAGSETTVSTAGSETTAAST----EDSETNTAFT 268

Query: 252 YGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQP 311
                T    STTGF T      G +    +++     G  TT  +T      T+ +   
Sbjct: 269 EDSKTTT--ASTTGFETTAASTTGSEPTMASTM-----GSETTMAST--IGPETTKVSTA 319

Query: 312 STNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGT-GLFGQTNTGFGAVGSTLFGNNKL 370
           S+    +F     +      G+ T T + T   T T  + G   +     GS        
Sbjct: 320 SSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE---TTTA 376

Query: 371 TTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
           +T GS TT+A + G+ +  +   G+ T+  SI  S+
Sbjct: 377 STEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 94/395 (23%), Positives = 157/395 (39%), Gaps = 39/395 (9%)

Query: 18  GTTSTFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72
           G+ +T    TG  TT+    G+     S  GS   T    G+  T       ++  S+  
Sbjct: 340 GSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTT-----ASTEGSEAT 394

Query: 73  TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132
           T ++TG    T + T +    T + G+ + +     F     +  G+  T  S+     T
Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454

Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192
           T +T     +T+ +  G  + TA  TG+       TG +T     + ++ +T      + 
Sbjct: 455 TASTEGS-ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-----AST 508

Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252
           +  E+ ++     E    + +G +N     TT    GS   T S TGL +++T+  G   
Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSEN-----TTVSTTGSETTTVSTTGLETTTTSTEGSEM 563

Query: 253 GQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPS 312
               T  G  TT   T   G        TT+  +   G  TTT +T  S   T++     
Sbjct: 564 TTVSTT-GAETTTDSTEGSG--------TTA--ASTAGSETTTVSTADSENTTASTADSE 612

Query: 313 TNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTT 372
           T +      T  S+      T++ T+T +  G+ T     T++    V +T       +T
Sbjct: 613 TTSAS----TTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITST 668

Query: 373 FGSSTTSAPSFGT-TSGGLFGFGTNTSGNSIFGSK 406
            GS TT+  + G+ T+    G GT T   SI GS+
Sbjct: 669 EGSETTTVSATGSETTVSTEGSGTTTV--SITGSE 701



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 99/409 (24%), Positives = 158/409 (38%), Gaps = 41/409 (10%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG------------GLFGTS 66
           T ST G  T   +T G    T +   S  T     +S+T                +F T+
Sbjct: 375 TASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETT 434

Query: 67  SFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTS 125
           + S   +  +      + T TA+T     +T T+  S    A+   ++ T   N G  T+
Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494

Query: 126 SGGLFGTTNTTSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGV---ST 180
           +    G+  TT++  GS  T+ S  G    T +  G+       TG++T   +     +T
Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240
             ST+   +T +    S +  E   +  + +     +  G+ TTT     S  T+++T  
Sbjct: 555 TTSTEGSEMTTV----STTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTA- 609

Query: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300
             S TT++     +  TA   STT   T      G +    T+  S    + T    TG 
Sbjct: 610 -DSETTSASTTGSETTTA---STTSSETTTASTEGSE----TTTVSTTDSETTMVSTTGS 661

Query: 301 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGT----AFGTGTGLFGQTNTG 356
               TST G  +T        T  S  G   GT T + TG+       TG+     +  G
Sbjct: 662 ERTITSTEGSETTTVSATGSETTVSTEGS--GTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 357 FGAVGSTLFGNNKLT--TFGSSTTSAPSFG--TTSGGLFGFGTNTSGNS 401
                +++ G+   T  T GS TT+A + G  TTS    G  T T+  +
Sbjct: 720 SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 91/400 (22%), Positives = 152/400 (38%), Gaps = 24/400 (6%)

Query: 19  TTSTFGQNTGFGTTSGG-AFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77
           T  T G +T   +T G      SA GS   T    G+  T       +++ S+  T ++T
Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTV-----STTGSETTTVSTT 549

Query: 78  GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTS 137
           G    T++   + +   ++TG    +           +  G+  T+ S+     TT +T+
Sbjct: 550 GLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTA 609

Query: 138 NPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYES 197
           +   +TS S  G  + TA+ T +        G++T     VST  S      T   E   
Sbjct: 610 DS-ETTSASTTGSETTTASTTSSETTTASTEGSETTT---VSTTDSETTMVSTTGSERTI 665

Query: 198 KSLEELRLEDYQANRKGPQNQV---GAGTTT-GLFGSSPATSSATGLFSSSTTNSGFAYG 253
            S E        A   G +  V   G+GTTT  + GS     S TG  +++T+  G    
Sbjct: 666 TSTEGSETTTVSAT--GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI- 722

Query: 254 QNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPST 313
              +  G+ TT   T          + + +  +   G  TTT +T  S    ++I    T
Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSET 782

Query: 314 NTMGLFG--VTQASQPGGLFGT--ATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNK 369
                 G   T+ S       T    N+ T  A  T +     +  G   + ++  G+  
Sbjct: 783 TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 370 LTTF---GSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
            TT    GS TT+A + G+ +       + T+  +  GS+
Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 77/327 (23%), Positives = 131/327 (40%), Gaps = 38/327 (11%)

Query: 71  PATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGF--------GNFGT 122
           PA  ++T     T + T   L   + T T+  S+  +      PTG         G+  T
Sbjct: 9   PAAGSNTTTASTTGSETTTILIKASETTTA--STAGSETTTPSPTGSQTTIVSISGSEIT 66

Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182
           +TS+ G   TT +++   G+T+ S+ G S  T +  G+       TGT+T + + + +  
Sbjct: 67  TTSTAGSENTTVSSAGS-GTTTASMAG-SETTVSTAGSETTTVSITGTETTMVSAMGSET 124

Query: 183 STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFS 242
           +T            S +  E  +     +     + VG+ TTT     S  T+++T    
Sbjct: 125 TT-----------NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSE 173

Query: 243 SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302
            +T  +  +     +  G+ TT   T           +TT++ +   G  TTT +T  S 
Sbjct: 174 MTTVFTAGSETITPSTAGSETTTVST--------AGSETTTVSTT--GSETTTASTAHSE 223

Query: 303 GN-TSTIGQPSTNTMGLFGVTQASQPGGLFGTAT--NTSTGTAFGTGTGLFGQTNTGFGA 359
               ST+G  +T        T  S  G     A+  ++ T TAF   +     + TGF  
Sbjct: 224 TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFET 283

Query: 360 VGSTLFGN--NKLTTFGSSTTSAPSFG 384
             ++  G+     +T GS TT A + G
Sbjct: 284 TAASTTGSEPTMASTMGSETTMASTIG 310



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 68/286 (23%), Positives = 102/286 (35%), Gaps = 48/286 (16%)

Query: 131 GTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC 188
           G+  TT++  GS + ++   +S   TA+  G+      PTG+ T + +   + I+T    
Sbjct: 12  GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTS-- 69

Query: 189 ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248
            TA  E  + S                    G+GTTT     S  T S  G  S +TT  
Sbjct: 70  -TAGSENTTVS------------------SAGSGTTTASMAGSETTVSTAG--SETTT-- 106

Query: 249 GFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTI 308
                        S TG  T      G +    T+  S    + T T   G      ST+
Sbjct: 107 ------------VSITGTETTMVSAMGSE----TTTNSTTSSETTVTSTAGSETTTVSTV 150

Query: 309 GQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNN 368
           G  +T        T A+   G   T   T+        T   G   T     GS      
Sbjct: 151 GSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTA--GSETTTVSTAGSE---TT 205

Query: 369 KLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGT 414
            ++T GS TT+A +  + +      G+ T+  S  GS+    T G+
Sbjct: 206 TVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS 251


>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 140/563 (24%), Positives = 218/563 (38%), Gaps = 73/563 (12%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTS 76
            TTST G  T   +T G    T++  SS  T      S+T      G  T++ S   + T+
Sbjct: 845  TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 77   TGFGFG------TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF-----GTSTS 125
            T    G      ++TG+  T   T  + T+  S++ +       TG         G+ T+
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 126  SGGLFGTTNTTSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIS 183
            +    G+  TT++  GS  T+ S  G  + TA+  G+       TG++T   +   T  +
Sbjct: 965  TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024

Query: 184  TKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSS 243
                 IT+ +  E+ ++     E       G +      TTT   GS   T S TG   S
Sbjct: 1025 -----ITSTEGSETTTVTTAGSETTAVYTTGSET-----TTTSTEGSETTTVSTTG---S 1071

Query: 244  STTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFG 303
             TT +  A  +  T    ST+G GT      G    +TT+++    G  TTT +T  S  
Sbjct: 1072 ETTTASTADLETTT---VSTSGSGTTTASTAG---SETTTVYIT--GSKTTTASTEGSEA 1123

Query: 304  NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363
             T +     T T      T  S+   +F T + T+T +  G+       T++  G+  +T
Sbjct: 1124 TTVSTTSSETTTAS----TTGSEMTTVFTTVSETTTVSTIGSE----ATTSSAAGSEATT 1175

Query: 364  LFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTA 423
                   +T GS TT+A + G+ +      G+ T+  S  GS+    T  +  G+   TA
Sbjct: 1176 ------TSTEGSETTTASTAGSETTTASTAGSETTTASTAGSET---TTASTSGSETNTA 1226

Query: 424  LGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTT---------TATLGFGAPQAPVALTDP 474
               G  +    + P   G     AF   G  TT         TAT   G+    V++T  
Sbjct: 1227 CTTGSET----STPSSAGSETNTAF-IIGSETTIASTASLEPTATSLTGSETTTVSITAS 1281

Query: 475  NASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYK 534
             A+AA   V          +     P+   PMS  +    RL      A  ++T      
Sbjct: 1282 GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRL-----TASSSVTMAPGMD 1336

Query: 535  LTPRPATRVRPK-ALQTTGTAKS 556
             T   A+   P   L T+G   S
Sbjct: 1337 FTASAASHTVPGIVLNTSGLGTS 1359



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 121/505 (23%), Positives = 182/505 (36%), Gaps = 66/505 (13%)

Query: 18   GTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77
            G+  T    TG  TT+    G+    +S     L   S T       T + S   + T+T
Sbjct: 910  GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS----ETITVSAEGSETTT 965

Query: 78   GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNTT 136
                G+ T TA+T     +T ++  S    A  + ++ T   + G+ T++    GT  T 
Sbjct: 966  VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTI 1025

Query: 137  SNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196
            ++  GS +      ++ T A + TT  +   TG++T      ST  S      T   E  
Sbjct: 1026 TSTEGSET------TTVTTAGSETTAVYT--TGSETTT---TSTEGSETTTVSTTGSETT 1074

Query: 197  SKSLEELRLEDYQANRKGPQNQVGAG---TTTGLFGSSPATSSATG-------LFSSSTT 246
            + S  +L       +  G      AG   TT  + GS   T+S  G         SS TT
Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 247  NSGFAYGQNKTAFGT-------STTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTG 299
             +     +  T F T       ST G         G +   T++      G  TTT +T 
Sbjct: 1135 TASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTST-----EGSETTTASTA 1189

Query: 300  FSFGNTSTIGQPSTNTMGLFG--VTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGF 357
             S   T++     T T    G   T AS  G    TA  T + T+  +  G   +TNT F
Sbjct: 1190 GSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAG--SETNTAF 1247

Query: 358  GAVGS--------------TLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSI- 402
              +GS              T    ++ TT   + + A +  TT        T  +  SI 
Sbjct: 1248 -IIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQ 1306

Query: 403  -FGSKPAPG--TLGTGLGAGFGTALGAGQ---ASLFGNNQPKIGGPLGTGAFGAPGFNTT 456
               + P  G  T GT L A     +  G    AS   +  P  G  L T   G      +
Sbjct: 1307 PITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVP--GIVLNTSGLGTSTMGAS 1364

Query: 457  TATLGFGAPQAPVALTDPNASAAQQ 481
            + T   G      +  +P +S  Q+
Sbjct: 1365 STTSAHGVRTTTGSTREPTSSTFQE 1389



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 89/396 (22%), Positives = 145/396 (36%), Gaps = 38/396 (9%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
           T S  G  T   + SG    T++   S NT      S T    + G+ +    A S +T 
Sbjct: 47  TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT 106

Query: 79  FGFGTSTGTANTLFGTASTGTSLFSSQNN--AFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136
                +  T  +  G+ +T  S  SS+    + A ++ T     G+ T++     +  T 
Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166

Query: 137 SNPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191
           ++  GS   ++F   S T  P+      TT+       T        +T  ST H   TA
Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTA 226

Query: 192 MKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251
                S++ +               +  G+ TT    GS    +S       S TN+ F 
Sbjct: 227 ASTMGSETTKV--------------STAGSETTVSTAGSETTAAST----EDSETNTAFT 268

Query: 252 YGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQP 311
                T    STTGF T      G +    +++     G  TT  +T      T+ +   
Sbjct: 269 EDSKTTT--ASTTGFETTAASTTGSEPTMASTM-----GSETTMAST--IGPETTKVSTA 319

Query: 312 STNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGT-GLFGQTNTGFGAVGSTLFGNNKL 370
           S+    +F     +      G+ T T + T   T T  + G   +     GS        
Sbjct: 320 SSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE---TTTA 376

Query: 371 TTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
           +T GS TT+A + G+ +  +   G+ T+  SI  S+
Sbjct: 377 STEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 94/395 (23%), Positives = 157/395 (39%), Gaps = 39/395 (9%)

Query: 18  GTTSTFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72
           G+ +T    TG  TT+    G+     S  GS   T    G+  T       ++  S+  
Sbjct: 340 GSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTT-----ASTEGSEAT 394

Query: 73  TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132
           T ++TG    T + T +    T + G+ + +     F     +  G+  T  S+     T
Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454

Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192
           T +T     +T+ +  G  + TA  TG+       TG +T     + ++ +T      + 
Sbjct: 455 TASTEGS-ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-----AST 508

Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252
           +  E+ ++     E    + +G +N     TT    GS   T S TGL +++T+  G   
Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSEN-----TTVSTTGSETTTVSTTGLETTTTSTEGSEM 563

Query: 253 GQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPS 312
               T  G  TT   T   G        TT+  +   G  TTT +T  S   T++     
Sbjct: 564 TTVSTT-GAETTTDSTEGSG--------TTA--ASTAGSETTTVSTADSENTTASTADSE 612

Query: 313 TNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTT 372
           T +      T  S+      T++ T+T +  G+ T     T++    V +T       +T
Sbjct: 613 TTSAS----TTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITST 668

Query: 373 FGSSTTSAPSFGT-TSGGLFGFGTNTSGNSIFGSK 406
            GS TT+  + G+ T+    G GT T   SI GS+
Sbjct: 669 EGSETTTVSATGSETTVSTEGSGTTTV--SITGSE 701



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 99/409 (24%), Positives = 158/409 (38%), Gaps = 41/409 (10%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG------------GLFGTS 66
           T ST G  T   +T G    T +   S  T     +S+T                +F T+
Sbjct: 375 TASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETT 434

Query: 67  SFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTS 125
           + S   +  +      + T TA+T     +T T+  S    A+   ++ T   N G  T+
Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494

Query: 126 SGGLFGTTNTTSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGV---ST 180
           +    G+  TT++  GS  T+ S  G    T +  G+       TG++T   +     +T
Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240
             ST+   +T +    S +  E   +  + +     +  G+ TTT     S  T+++T  
Sbjct: 555 TTSTEGSEMTTV----STTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTA- 609

Query: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300
             S TT++     +  TA   STT   T      G +    T+  S    + T    TG 
Sbjct: 610 -DSETTSASTTGSETTTA---STTSSETTTASTEGSE----TTTVSTTDSETTMVSTTGS 661

Query: 301 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGT----AFGTGTGLFGQTNTG 356
               TST G  +T        T  S  G   GT T + TG+       TG+     +  G
Sbjct: 662 ERTITSTEGSETTTVSATGSETTVSTEGS--GTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 357 FGAVGSTLFGNNKLT--TFGSSTTSAPSFG--TTSGGLFGFGTNTSGNS 401
                +++ G+   T  T GS TT+A + G  TTS    G  T T+  +
Sbjct: 720 SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 91/400 (22%), Positives = 152/400 (38%), Gaps = 24/400 (6%)

Query: 19  TTSTFGQNTGFGTTSGG-AFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77
           T  T G +T   +T G      SA GS   T    G+  T       +++ S+  T ++T
Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTV-----STTGSETTTVSTT 549

Query: 78  GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTS 137
           G    T++   + +   ++TG    +           +  G+  T+ S+     TT +T+
Sbjct: 550 GLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTA 609

Query: 138 NPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYES 197
           +   +TS S  G  + TA+ T +        G++T     VST  S      T   E   
Sbjct: 610 DS-ETTSASTTGSETTTASTTSSETTTASTEGSETTT---VSTTDSETTMVSTTGSERTI 665

Query: 198 KSLEELRLEDYQANRKGPQNQV---GAGTTT-GLFGSSPATSSATGLFSSSTTNSGFAYG 253
            S E        A   G +  V   G+GTTT  + GS     S TG  +++T+  G    
Sbjct: 666 TSTEGSETTTVSAT--GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI- 722

Query: 254 QNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPST 313
              +  G+ TT   T          + + +  +   G  TTT +T  S    ++I    T
Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSET 782

Query: 314 NTMGLFG--VTQASQPGGLFGT--ATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNK 369
                 G   T+ S       T    N+ T  A  T +     +  G   + ++  G+  
Sbjct: 783 TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 370 LTTF---GSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
            TT    GS TT+A + G+ +       + T+  +  GS+
Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 77/327 (23%), Positives = 131/327 (40%), Gaps = 38/327 (11%)

Query: 71  PATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGF--------GNFGT 122
           PA  ++T     T + T   L   + T T+  S+  +      PTG         G+  T
Sbjct: 9   PAAGSNTTTASTTGSETTTILIKASETTTA--STAGSETTTPSPTGSQTTIVSISGSEIT 66

Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182
           +TS+ G   TT +++   G+T+ S+ G S  T +  G+       TGT+T + + + +  
Sbjct: 67  TTSTAGSENTTVSSAGS-GTTTASMAG-SETTVSTAGSETTTVSITGTETTMVSAMGSET 124

Query: 183 STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFS 242
           +T            S +  E  +     +     + VG+ TTT     S  T+++T    
Sbjct: 125 TT-----------NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSE 173

Query: 243 SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302
            +T  +  +     +  G+ TT   T           +TT++ +   G  TTT +T  S 
Sbjct: 174 MTTVFTAGSETITPSTAGSETTTVST--------AGSETTTVSTT--GSETTTASTAHSE 223

Query: 303 GN-TSTIGQPSTNTMGLFGVTQASQPGGLFGTAT--NTSTGTAFGTGTGLFGQTNTGFGA 359
               ST+G  +T        T  S  G     A+  ++ T TAF   +     + TGF  
Sbjct: 224 TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFET 283

Query: 360 VGSTLFGN--NKLTTFGSSTTSAPSFG 384
             ++  G+     +T GS TT A + G
Sbjct: 284 TAASTTGSEPTMASTMGSETTMASTIG 310



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 68/286 (23%), Positives = 102/286 (35%), Gaps = 48/286 (16%)

Query: 131 GTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC 188
           G+  TT++  GS + ++   +S   TA+  G+      PTG+ T + +   + I+T    
Sbjct: 12  GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTS-- 69

Query: 189 ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248
            TA  E  + S                    G+GTTT     S  T S  G  S +TT  
Sbjct: 70  -TAGSENTTVS------------------SAGSGTTTASMAGSETTVSTAG--SETTT-- 106

Query: 249 GFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTI 308
                        S TG  T      G +    T+  S    + T T   G      ST+
Sbjct: 107 ------------VSITGTETTMVSAMGSE----TTTNSTTSSETTVTSTAGSETTTVSTV 150

Query: 309 GQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNN 368
           G  +T        T A+   G   T   T+        T   G   T     GS      
Sbjct: 151 GSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTA--GSETTTVSTAGSE---TT 205

Query: 369 KLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGT 414
            ++T GS TT+A +  + +      G+ T+  S  GS+    T G+
Sbjct: 206 TVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS 251


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 142/556 (25%), Positives = 215/556 (38%), Gaps = 69/556 (12%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTS 76
            TTST G  T   +T G    T++  SS  T      S+T      G  T++ S   + T+
Sbjct: 845  TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 77   TGFGFG------TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF-----GTSTS 125
            T    G      ++TG+  T   T  + T+  S++ +       TG         G+ T+
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 126  SGGLFGTTNTTSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIS 183
            +    G+  TT++  GS  T+ S  G  + TA+  G+       TG++T   +   T  +
Sbjct: 965  TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024

Query: 184  TKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSS 243
                 IT+ +  E+ ++     E       G +      TTT   GS   T S TG   S
Sbjct: 1025 -----ITSTEGSETTTVTTAGSETTAVYTTGSET-----TTTSTEGSETTTVSTTG---S 1071

Query: 244  STTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFG 303
             TT +  A  +  T    ST+G GT      G    +TT+++    G  TTT +T  S  
Sbjct: 1072 ETTTASTADLETTT---VSTSGSGTTTASTAG---SETTTVYIT--GSKTTTASTEGSEA 1123

Query: 304  NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363
             T +     T T      T  S+   +F T + T+T +  G+       T++  G+  +T
Sbjct: 1124 TTVSTTSSETTTAS----TTGSEMTTVFTTVSETTTVSTIGSE----ATTSSAAGSEATT 1175

Query: 364  LFGNNKLTTFGSSTTSAPSFG--TTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFG 421
                   +T GS TT+A + G  TT+    G  T T+  S   +  A  T     G+   
Sbjct: 1176 ------TSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTT-----GSETS 1224

Query: 422  TALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQ 481
            T   AG  +    N   I G   T A  A      TAT   G+    V++T   A+AA  
Sbjct: 1225 TPSSAGSET----NTAFIIGSETTIASTAS--LEPTATSLTGSETTTVSITASGATAAST 1278

Query: 482  AVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPAT 541
             V          +     P+   PMS       R   T P A  ++T       T   A+
Sbjct: 1279 TVSSTTFVLTKATDVSIQPITNTPMSG-----TRTTGTRPTASSSVTMAPGMDFTASAAS 1333

Query: 542  RVRPK-ALQTTGTAKS 556
               P   L T+G   S
Sbjct: 1334 HTVPGIVLNTSGLGTS 1349



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 89/396 (22%), Positives = 145/396 (36%), Gaps = 38/396 (9%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
           T S  G  T   + SG    T++   S NT      S T    + G+ +    A S +T 
Sbjct: 47  TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT 106

Query: 79  FGFGTSTGTANTLFGTASTGTSLFSSQNN--AFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136
                +  T  +  G+ +T  S  SS+    + A ++ T     G+ T++     +  T 
Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166

Query: 137 SNPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191
           ++  GS   ++F   S T  P+      TT+       T        +T  ST H   TA
Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTA 226

Query: 192 MKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251
                S++ +               +  G+ TT    GS    +S       S TN+ F 
Sbjct: 227 ASTMGSETTKV--------------STAGSETTVSTAGSETTAAST----EDSETNTAFT 268

Query: 252 YGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQP 311
                T    STTGF T      G +    +++     G  TT  +T      T+ +   
Sbjct: 269 EDSKTTT--ASTTGFETTAASTTGSEPTMASTM-----GSETTMAST--IGPETTKVSTA 319

Query: 312 STNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGT-GLFGQTNTGFGAVGSTLFGNNKL 370
           S+    +F     +      G+ T T + T   T T  + G   +     GS        
Sbjct: 320 SSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE---TTTA 376

Query: 371 TTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
           +T GS TT+A + G+ +  +   G+ T+  SI  S+
Sbjct: 377 STEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 94/395 (23%), Positives = 157/395 (39%), Gaps = 39/395 (9%)

Query: 18  GTTSTFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72
           G+ +T    TG  TT+    G+     S  GS   T    G+  T       ++  S+  
Sbjct: 340 GSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTT-----ASTEGSEAT 394

Query: 73  TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132
           T ++TG    T + T +    T + G+ + +     F     +  G+  T  S+     T
Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454

Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192
           T +T     +T+ +  G  + TA  TG+       TG +T     + ++ +T      + 
Sbjct: 455 TASTEGS-ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-----AST 508

Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252
           +  E+ ++     E    + +G +N     TT    GS   T S TGL +++T+  G   
Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSEN-----TTVSTTGSETTTVSTTGLETTTTSTEGSEM 563

Query: 253 GQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPS 312
               T  G  TT   T   G        TT+  +   G  TTT +T  S   T++     
Sbjct: 564 TTVSTT-GAETTTDSTEGSG--------TTA--ASTAGSETTTVSTADSENTTASTADSE 612

Query: 313 TNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTT 372
           T +      T  S+      T++ T+T +  G+ T     T++    V +T       +T
Sbjct: 613 TTSAS----TTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITST 668

Query: 373 FGSSTTSAPSFGT-TSGGLFGFGTNTSGNSIFGSK 406
            GS TT+  + G+ T+    G GT T   SI GS+
Sbjct: 669 EGSETTTVSATGSETTVSTEGSGTTTV--SITGSE 701



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 99/409 (24%), Positives = 158/409 (38%), Gaps = 41/409 (10%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG------------GLFGTS 66
           T ST G  T   +T G    T +   S  T     +S+T                +F T+
Sbjct: 375 TASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETT 434

Query: 67  SFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTS 125
           + S   +  +      + T TA+T     +T T+  S    A+   ++ T   N G  T+
Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494

Query: 126 SGGLFGTTNTTSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGV---ST 180
           +    G+  TT++  GS  T+ S  G    T +  G+       TG++T   +     +T
Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240
             ST+   +T +    S +  E   +  + +     +  G+ TTT     S  T+++T  
Sbjct: 555 TTSTEGSEMTTV----STTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTA- 609

Query: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300
             S TT++     +  TA   STT   T      G +    T+  S    + T    TG 
Sbjct: 610 -DSETTSASTTGSETTTA---STTSSETTTASTEGSE----TTTVSTTDSETTMVSTTGS 661

Query: 301 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGT----AFGTGTGLFGQTNTG 356
               TST G  +T        T  S  G   GT T + TG+       TG+     +  G
Sbjct: 662 ERTITSTEGSETTTVSATGSETTVSTEGS--GTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 357 FGAVGSTLFGNNKLT--TFGSSTTSAPSFG--TTSGGLFGFGTNTSGNS 401
                +++ G+   T  T GS TT+A + G  TTS    G  T T+  +
Sbjct: 720 SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 91/400 (22%), Positives = 152/400 (38%), Gaps = 24/400 (6%)

Query: 19  TTSTFGQNTGFGTTSGG-AFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77
           T  T G +T   +T G      SA GS   T    G+  T       +++ S+  T ++T
Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTV-----STTGSETTTVSTT 549

Query: 78  GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTS 137
           G    T++   + +   ++TG    +           +  G+  T+ S+     TT +T+
Sbjct: 550 GLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTA 609

Query: 138 NPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYES 197
           +   +TS S  G  + TA+ T +        G++T     VST  S      T   E   
Sbjct: 610 DS-ETTSASTTGSETTTASTTSSETTTASTEGSETTT---VSTTDSETTMVSTTGSERTI 665

Query: 198 KSLEELRLEDYQANRKGPQNQV---GAGTTT-GLFGSSPATSSATGLFSSSTTNSGFAYG 253
            S E        A   G +  V   G+GTTT  + GS     S TG  +++T+  G    
Sbjct: 666 TSTEGSETTTVSAT--GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI- 722

Query: 254 QNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPST 313
              +  G+ TT   T          + + +  +   G  TTT +T  S    ++I    T
Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSET 782

Query: 314 NTMGLFG--VTQASQPGGLFGT--ATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNK 369
                 G   T+ S       T    N+ T  A  T +     +  G   + ++  G+  
Sbjct: 783 TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 370 LTTF---GSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
            TT    GS TT+A + G+ +       + T+  +  GS+
Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 77/327 (23%), Positives = 131/327 (40%), Gaps = 38/327 (11%)

Query: 71  PATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGF--------GNFGT 122
           PA  ++T     T + T   L   + T T+  S+  +      PTG         G+  T
Sbjct: 9   PAAGSNTTTASTTGSETTTILIKASETTTA--STAGSETTTPSPTGSQTTIVSISGSEIT 66

Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182
           +TS+ G   TT +++   G+T+ S+ G S  T +  G+       TGT+T + + + +  
Sbjct: 67  TTSTAGSENTTVSSAGS-GTTTASMAG-SETTVSTAGSETTTVSITGTETTMVSAMGSET 124

Query: 183 STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFS 242
           +T            S +  E  +     +     + VG+ TTT     S  T+++T    
Sbjct: 125 TT-----------NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSE 173

Query: 243 SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302
            +T  +  +     +  G+ TT   T           +TT++ +   G  TTT +T  S 
Sbjct: 174 MTTVFTAGSETITPSTAGSETTTVST--------AGSETTTVSTT--GSETTTASTAHSE 223

Query: 303 GN-TSTIGQPSTNTMGLFGVTQASQPGGLFGTAT--NTSTGTAFGTGTGLFGQTNTGFGA 359
               ST+G  +T        T  S  G     A+  ++ T TAF   +     + TGF  
Sbjct: 224 TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFET 283

Query: 360 VGSTLFGN--NKLTTFGSSTTSAPSFG 384
             ++  G+     +T GS TT A + G
Sbjct: 284 TAASTTGSEPTMASTMGSETTMASTIG 310



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 68/286 (23%), Positives = 102/286 (35%), Gaps = 48/286 (16%)

Query: 131 GTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC 188
           G+  TT++  GS + ++   +S   TA+  G+      PTG+ T + +   + I+T    
Sbjct: 12  GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTS-- 69

Query: 189 ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248
            TA  E  + S                    G+GTTT     S  T S  G  S +TT  
Sbjct: 70  -TAGSENTTVS------------------SAGSGTTTASMAGSETTVSTAG--SETTT-- 106

Query: 249 GFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTI 308
                        S TG  T      G +    T+  S    + T T   G      ST+
Sbjct: 107 ------------VSITGTETTMVSAMGSE----TTTNSTTSSETTVTSTAGSETTTVSTV 150

Query: 309 GQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNN 368
           G  +T        T A+   G   T   T+        T   G   T     GS      
Sbjct: 151 GSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTA--GSETTTVSTAGSE---TT 205

Query: 369 KLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGT 414
            ++T GS TT+A +  + +      G+ T+  S  GS+    T G+
Sbjct: 206 TVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS 251


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 142/556 (25%), Positives = 215/556 (38%), Gaps = 69/556 (12%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTS 76
            TTST G  T   +T G    T++  SS  T      S+T      G  T++ S   + T+
Sbjct: 845  TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 77   TGFGFG------TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF-----GTSTS 125
            T    G      ++TG+  T   T  + T+  S++ +       TG         G+ T+
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 126  SGGLFGTTNTTSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIS 183
            +    G+  TT++  GS  T+ S  G  + TA+  G+       TG++T   +   T  +
Sbjct: 965  TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024

Query: 184  TKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSS 243
                 IT+ +  E+ ++     E       G +      TTT   GS   T S TG   S
Sbjct: 1025 -----ITSTEGSETTTVTTAGSETTAVYTTGSET-----TTTSTEGSETTTVSTTG---S 1071

Query: 244  STTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFG 303
             TT +  A  +  T    ST+G GT      G    +TT+++    G  TTT +T  S  
Sbjct: 1072 ETTTASTADLETTT---VSTSGSGTTTASTAG---SETTTVYIT--GSKTTTASTEGSEA 1123

Query: 304  NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363
             T +     T T      T  S+   +F T + T+T +  G+       T++  G+  +T
Sbjct: 1124 TTVSTTSSETTTAS----TTGSEMTTVFTTVSETTTVSTIGSE----ATTSSAAGSEATT 1175

Query: 364  LFGNNKLTTFGSSTTSAPSFG--TTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFG 421
                   +T GS TT+A + G  TT+    G  T T+  S   +  A  T     G+   
Sbjct: 1176 ------TSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTT-----GSETS 1224

Query: 422  TALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQ 481
            T   AG  +    N   I G   T A  A      TAT   G+    V++T   A+AA  
Sbjct: 1225 TPSSAGSET----NTAFIIGSETTIASTAS--LEPTATSLTGSETTTVSITASGATAAST 1278

Query: 482  AVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPAT 541
             V          +     P+   PMS       R   T P A  ++T       T   A+
Sbjct: 1279 TVSSTTFVLTKATDVSIQPITNTPMSG-----TRTTGTRPTASSSVTMAPGMDFTASAAS 1333

Query: 542  RVRPK-ALQTTGTAKS 556
               P   L T+G   S
Sbjct: 1334 HTVPGIVLNTSGLGTS 1349



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 89/396 (22%), Positives = 145/396 (36%), Gaps = 38/396 (9%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
           T S  G  T   + SG    T++   S NT      S T    + G+ +    A S +T 
Sbjct: 47  TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT 106

Query: 79  FGFGTSTGTANTLFGTASTGTSLFSSQNN--AFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136
                +  T  +  G+ +T  S  SS+    + A ++ T     G+ T++     +  T 
Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166

Query: 137 SNPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191
           ++  GS   ++F   S T  P+      TT+       T        +T  ST H   TA
Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTA 226

Query: 192 MKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251
                S++ +               +  G+ TT    GS    +S       S TN+ F 
Sbjct: 227 ASTMGSETTKV--------------STAGSETTVSTAGSETTAAST----EDSETNTAFT 268

Query: 252 YGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQP 311
                T    STTGF T      G +    +++     G  TT  +T      T+ +   
Sbjct: 269 EDSKTTT--ASTTGFETTAASTTGSEPTMASTM-----GSETTMAST--IGPETTKVSTA 319

Query: 312 STNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGT-GLFGQTNTGFGAVGSTLFGNNKL 370
           S+    +F     +      G+ T T + T   T T  + G   +     GS        
Sbjct: 320 SSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE---TTTA 376

Query: 371 TTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
           +T GS TT+A + G+ +  +   G+ T+  SI  S+
Sbjct: 377 STEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 94/395 (23%), Positives = 157/395 (39%), Gaps = 39/395 (9%)

Query: 18  GTTSTFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72
           G+ +T    TG  TT+    G+     S  GS   T    G+  T       ++  S+  
Sbjct: 340 GSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTT-----ASTEGSEAT 394

Query: 73  TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132
           T ++TG    T + T +    T + G+ + +     F     +  G+  T  S+     T
Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454

Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192
           T +T     +T+ +  G  + TA  TG+       TG +T     + ++ +T      + 
Sbjct: 455 TASTEGS-ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-----AST 508

Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252
           +  E+ ++     E    + +G +N     TT    GS   T S TGL +++T+  G   
Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSEN-----TTVSTTGSETTTVSTTGLETTTTSTEGSEM 563

Query: 253 GQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPS 312
               T  G  TT   T   G        TT+  +   G  TTT +T  S   T++     
Sbjct: 564 TTVSTT-GAETTTDSTEGSG--------TTA--ASTAGSETTTVSTADSENTTASTADSE 612

Query: 313 TNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTT 372
           T +      T  S+      T++ T+T +  G+ T     T++    V +T       +T
Sbjct: 613 TTSAS----TTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITST 668

Query: 373 FGSSTTSAPSFGT-TSGGLFGFGTNTSGNSIFGSK 406
            GS TT+  + G+ T+    G GT T   SI GS+
Sbjct: 669 EGSETTTVSATGSETTVSTEGSGTTTV--SITGSE 701



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 99/409 (24%), Positives = 158/409 (38%), Gaps = 41/409 (10%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG------------GLFGTS 66
           T ST G  T   +T G    T +   S  T     +S+T                +F T+
Sbjct: 375 TASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETT 434

Query: 67  SFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTS 125
           + S   +  +      + T TA+T     +T T+  S    A+   ++ T   N G  T+
Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494

Query: 126 SGGLFGTTNTTSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGV---ST 180
           +    G+  TT++  GS  T+ S  G    T +  G+       TG++T   +     +T
Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240
             ST+   +T +    S +  E   +  + +     +  G+ TTT     S  T+++T  
Sbjct: 555 TTSTEGSEMTTV----STTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTA- 609

Query: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300
             S TT++     +  TA   STT   T      G +    T+  S    + T    TG 
Sbjct: 610 -DSETTSASTTGSETTTA---STTSSETTTASTEGSE----TTTVSTTDSETTMVSTTGS 661

Query: 301 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGT----AFGTGTGLFGQTNTG 356
               TST G  +T        T  S  G   GT T + TG+       TG+     +  G
Sbjct: 662 ERTITSTEGSETTTVSATGSETTVSTEGS--GTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 357 FGAVGSTLFGNNKLT--TFGSSTTSAPSFG--TTSGGLFGFGTNTSGNS 401
                +++ G+   T  T GS TT+A + G  TTS    G  T T+  +
Sbjct: 720 SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 91/400 (22%), Positives = 152/400 (38%), Gaps = 24/400 (6%)

Query: 19  TTSTFGQNTGFGTTSGG-AFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77
           T  T G +T   +T G      SA GS   T    G+  T       +++ S+  T ++T
Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTV-----STTGSETTTVSTT 549

Query: 78  GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTS 137
           G    T++   + +   ++TG    +           +  G+  T+ S+     TT +T+
Sbjct: 550 GLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTA 609

Query: 138 NPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYES 197
           +   +TS S  G  + TA+ T +        G++T     VST  S      T   E   
Sbjct: 610 DS-ETTSASTTGSETTTASTTSSETTTASTEGSETTT---VSTTDSETTMVSTTGSERTI 665

Query: 198 KSLEELRLEDYQANRKGPQNQV---GAGTTT-GLFGSSPATSSATGLFSSSTTNSGFAYG 253
            S E        A   G +  V   G+GTTT  + GS     S TG  +++T+  G    
Sbjct: 666 TSTEGSETTTVSAT--GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI- 722

Query: 254 QNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPST 313
              +  G+ TT   T          + + +  +   G  TTT +T  S    ++I    T
Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSET 782

Query: 314 NTMGLFG--VTQASQPGGLFGT--ATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNK 369
                 G   T+ S       T    N+ T  A  T +     +  G   + ++  G+  
Sbjct: 783 TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 370 LTTF---GSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
            TT    GS TT+A + G+ +       + T+  +  GS+
Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 77/327 (23%), Positives = 131/327 (40%), Gaps = 38/327 (11%)

Query: 71  PATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGF--------GNFGT 122
           PA  ++T     T + T   L   + T T+  S+  +      PTG         G+  T
Sbjct: 9   PAAGSNTTTASTTGSETTTILIKASETTTA--STAGSETTTPSPTGSQTTIVSISGSEIT 66

Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182
           +TS+ G   TT +++   G+T+ S+ G S  T +  G+       TGT+T + + + +  
Sbjct: 67  TTSTAGSENTTVSSAGS-GTTTASMAG-SETTVSTAGSETTTVSITGTETTMVSAMGSET 124

Query: 183 STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFS 242
           +T            S +  E  +     +     + VG+ TTT     S  T+++T    
Sbjct: 125 TT-----------NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSE 173

Query: 243 SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302
            +T  +  +     +  G+ TT   T           +TT++ +   G  TTT +T  S 
Sbjct: 174 MTTVFTAGSETITPSTAGSETTTVST--------AGSETTTVSTT--GSETTTASTAHSE 223

Query: 303 GN-TSTIGQPSTNTMGLFGVTQASQPGGLFGTAT--NTSTGTAFGTGTGLFGQTNTGFGA 359
               ST+G  +T        T  S  G     A+  ++ T TAF   +     + TGF  
Sbjct: 224 TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFET 283

Query: 360 VGSTLFGN--NKLTTFGSSTTSAPSFG 384
             ++  G+     +T GS TT A + G
Sbjct: 284 TAASTTGSEPTMASTMGSETTMASTIG 310



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 68/286 (23%), Positives = 102/286 (35%), Gaps = 48/286 (16%)

Query: 131 GTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC 188
           G+  TT++  GS + ++   +S   TA+  G+      PTG+ T + +   + I+T    
Sbjct: 12  GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTS-- 69

Query: 189 ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248
            TA  E  + S                    G+GTTT     S  T S  G  S +TT  
Sbjct: 70  -TAGSENTTVS------------------SAGSGTTTASMAGSETTVSTAG--SETTT-- 106

Query: 249 GFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTI 308
                        S TG  T      G +    T+  S    + T T   G      ST+
Sbjct: 107 ------------VSITGTETTMVSAMGSE----TTTNSTTSSETTVTSTAGSETTTVSTV 150

Query: 309 GQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNN 368
           G  +T        T A+   G   T   T+        T   G   T     GS      
Sbjct: 151 GSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTA--GSETTTVSTAGSE---TT 205

Query: 369 KLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGT 414
            ++T GS TT+A +  + +      G+ T+  S  GS+    T G+
Sbjct: 206 TVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS 251


>gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo
           sapiens]
          Length = 834

 Score = 84.3 bits (207), Expect = 9e-16
 Identities = 125/440 (28%), Positives = 182/440 (41%), Gaps = 89/440 (20%)

Query: 85  TGTANTLFGTASTGTS---LFSSQNNAFAQNKPT-GFGNFGTSTSSGGLFGTTNTTSNPF 140
           T TA    G AS  ++   + S+  +  + +KP  GFG    S+SS      + TTS   
Sbjct: 386 TTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSS-----VSTTTSTAT 440

Query: 141 GSTSGSLFGP-----SSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCI-TAMKE 194
            ++   LFG      +SFT A  G+  +F  P    T      +T ++T  Q + TA+  
Sbjct: 441 AASQPFLFGAPQASAASFTPA-MGSIFQFGKPPALPT------TTTVTTFSQSLPTAVPT 493

Query: 195 YESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQ 254
             S S  +                 G G+T  L  S+PATSS   L  S+T+   F    
Sbjct: 494 ATSSSAADFS---------------GFGST--LATSAPATSSQPTLTFSNTSTPTFNIPF 536

Query: 255 NKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTST-IGQPST 313
             +A     +  G NP   FG    Q     +KP    T +  + F+FGN++     P+ 
Sbjct: 537 GSSAKSPLPSYPGANPQPAFGAAEGQPPGA-AKP--ALTPSFGSSFTFGNSAAPAAAPTP 593

Query: 314 NTMGLFGVTQASQPGGL---FGTATNTSTGT---------------AFGTGTGLFG---Q 352
               +  +  A  P  +   FG AT+++ G                AFG  T +F     
Sbjct: 594 APPSMIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAA 653

Query: 353 TNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTS----GGLFGFGTNTSGNSI------ 402
           T++GFGA   T    +  + FGS+T S  +FG ++     G FG    T G+S       
Sbjct: 654 TSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGAFS 713

Query: 403 FGSKPAPGT-LGTGLGAGFG-TALG-AGQASLFGNN-------QPKIGGPLGTGAFG--- 449
           FG+  +  T   T    G G  ALG  GQ++ F  N       +P  GG   T  FG   
Sbjct: 714 FGAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGG-TATPTFGLNT 772

Query: 450 -APGFNTTTATLGFGAPQAP 468
            APG  T+ ++L FGA  AP
Sbjct: 773 PAPGVGTSGSSLSFGASSAP 792



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 118/474 (24%), Positives = 173/474 (36%), Gaps = 72/474 (15%)

Query: 69  SQPATSTSTGFGFGT-STGTANTLFGTASTGTSLFSSQNNAFAQNK-----PTGFGNFGT 122
           S P+ +    F FGT +T  ++     AS+ + +F     A  +++     P G     T
Sbjct: 278 SAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVSAT 337

Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSF-------------TAAPTGTTIKF----N 165
           + SS  L  TT+TT+  F     S+  P+S                APT T   F    +
Sbjct: 338 APSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLAS 397

Query: 166 PPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRK---GPQNQVGAG 222
             +    +  A  ST+ ++K      +    S S+         A++    G      A 
Sbjct: 398 ATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAAS 457

Query: 223 TTTGL-----FGSSPA--TSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFG 275
            T  +     FG  PA  T++    FS S      A     ++     +GFG+       
Sbjct: 458 FTPAMGSIFQFGKPPALPTTTTVTTFSQSLPT---AVPTATSSSAADFSGFGSTLATSAP 514

Query: 276 QQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPS---TNTMGLFGVTQASQPGGLFG 332
             + Q T  FS      T+T      FG+++    PS    N    FG  +  QP G   
Sbjct: 515 ATSSQPTLTFSN-----TSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAE-GQPPGAAK 568

Query: 333 TATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFG 392
            A   S G++F      FG +     A         K+      T   P+FG  +   FG
Sbjct: 569 PALTPSFGSSF-----TFGNSAAPAAAPTPAPPSMIKIVPAHVPTPIQPTFGGATHSAFG 623

Query: 393 -------FGTNTSGNSIFGSKPAPGTLGTGLGAGFG----TALGAGQASLFGNNQPK--- 438
                  FG   S    FG   A  + G    +GFG    TA     +S+FG+  P    
Sbjct: 624 LKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFT 683

Query: 439 IGG---PLGTGAFG----APGFNTTTATLGFGAPQA-PVALTDPNASAAQQAVL 484
            GG   P G+G+FG     PG + TT    FGA Q+   A + P A    Q  L
Sbjct: 684 FGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQSGSTATSTPFAGGLGQNAL 737



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 112/436 (25%), Positives = 153/436 (35%), Gaps = 95/436 (21%)

Query: 6   FGTPFGGG---TGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGL 62
           FG P       T   G+   FG+     TT+     + +  ++  T     +S     G 
Sbjct: 448 FGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTAT--SSSAADFSGF 505

Query: 63  FGTSSFSQPATSTSTGFGFG-TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFG 121
             T + S PATS+     F  TST T N  FG  S+  S   S   A   N    FG   
Sbjct: 506 GSTLATSAPATSSQPTLTFSNTSTPTFNIPFG--SSAKSPLPSYPGA---NPQPAFG--- 557

Query: 122 TSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTN 181
              + G   G       P   +S +    ++  AAPT        P     +V A V T 
Sbjct: 558 --AAEGQPPGAAKPALTPSFGSSFTFGNSAAPAAAPTPA------PPSMIKIVPAHVPTP 609

Query: 182 ISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFG----SSPATSSA 237
           I       T                          +  G   T   FG    S PA   +
Sbjct: 610 IQPTFGGAT-------------------------HSAFGLKATASAFGAPASSQPAFGGS 644

Query: 238 TGLFS-SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQ 296
           T +FS  + T+SGF       + G+S++ FG+            T S F+  FG +    
Sbjct: 645 TAVFSFGAATSSGFGATTQTASSGSSSSVFGST-----------TPSPFT--FGGSAAPA 691

Query: 297 NTGFSFG-NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQT-- 353
            +G SFG N +T G  +T     FG  Q+         +T TST  A G G    G T  
Sbjct: 692 GSG-SFGINVATPGSSATTGAFSFGAGQSG--------STATSTPFAGGLGQNALGTTGQ 742

Query: 354 ------NTGFGAVGSTLFGNNKLTTFGSSTT--------SAPSFGTTSGGLFGFGTNTSG 399
                 N G       +FG     TFG +T         S+ SFG +S    GF     G
Sbjct: 743 STPFAFNVGSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASSAPAQGF----VG 798

Query: 400 NSIFGSKPAPGTLGTG 415
            + FGS     ++G G
Sbjct: 799 VAPFGSAAPSFSIGAG 814



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 61/199 (30%), Positives = 84/199 (42%), Gaps = 40/199 (20%)

Query: 5   SFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFG----TSAFGSSNNTGG-------LFG 53
           +FG P        G+T+ F     FG  +   FG    T++ GSS++  G        FG
Sbjct: 630 AFGAPASSQPAFGGSTAVFS----FGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFG 685

Query: 54  NSQTKPG-GLFGTSSFSQPATSTSTG---FGFGTSTGTANTLFGTASTGTSLFSSQNNAF 109
            S    G G FG  + + P +S +TG   FG G S  TA +       G +   +     
Sbjct: 686 GSAAPAGSGSFGI-NVATPGSSATTGAFSFGAGQSGSTATSTPFAGGLGQNALGTT---- 740

Query: 110 AQNKPTGFGNFGTSTSSGGLFGTTNT------TSNPFGSTSGS--LFGPSSFTA------ 155
            Q+ P  F N G++T S  +FG T T      T  P   TSGS   FG SS  A      
Sbjct: 741 GQSTPFAF-NVGSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASSAPAQGFVGV 799

Query: 156 APTGTTI-KFNPPTGTDTM 173
           AP G+    F+   G+ T+
Sbjct: 800 APFGSAAPSFSIGAGSKTL 818


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 141/556 (25%), Positives = 215/556 (38%), Gaps = 69/556 (12%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTS 76
            TTST G  T   +T G    T++  SS  T      S+T      G  T++ S   + T+
Sbjct: 845  TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 77   TGFGFG------TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF-----GTSTS 125
            T    G      ++TG+  T   T  + T+  S++ +       TG         G+ T+
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 126  SGGLFGTTNTTSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIS 183
            +    G+  TT++  GS  T+ S  G  + TA+  G+       TG++T   +   T  +
Sbjct: 965  TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024

Query: 184  TKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSS 243
                 IT+ +  E+ ++     E       G +      TTT   GS   T S TG   S
Sbjct: 1025 -----ITSTEGSETTTVTTAGSETTAVYTTGSET-----TTTSTEGSETTTVSTTG---S 1071

Query: 244  STTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFG 303
             TT +  A  +  T    ST+G GT      G    +TT+++    G  TTT +T  S  
Sbjct: 1072 ETTTASTADLETTT---VSTSGSGTTTASTAG---SETTTVYIT--GSKTTTASTEGSEA 1123

Query: 304  NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363
             T +     T T      T  S+   +F T + T+T +  G+       T++  G+  +T
Sbjct: 1124 TTVSTTSSETTTAS----TTGSEMTTVFTTVSETTTVSTIGSE----ATTSSAAGSEATT 1175

Query: 364  LFGNNKLTTFGSSTTSAPSFG--TTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFG 421
                   +T GS TT+A + G  TT+    G  T T+  S   +  A  T     G+   
Sbjct: 1176 ------TSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTT-----GSETS 1224

Query: 422  TALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQ 481
            T   AG  +    N   I G   T A  A      TAT   G+    V++T   A+AA  
Sbjct: 1225 TPSSAGSET----NTAFIIGSESTIASTAS--LEPTATSLTGSETTTVSITASGATAAST 1278

Query: 482  AVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPAT 541
             V          +     P+   PMS  +    RL      A  ++T       T   A+
Sbjct: 1279 TVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRL-----TASSSVTMAPGMDFTASAAS 1333

Query: 542  RVRPK-ALQTTGTAKS 556
               P   L T+G   S
Sbjct: 1334 HTVPGIVLNTSGLGTS 1349



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 124/499 (24%), Positives = 182/499 (36%), Gaps = 64/499 (12%)

Query: 18   GTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77
            G+  T    TG  TT+    G+    +S     L   S T       T + S   + T+T
Sbjct: 910  GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS----ETITVSAEGSETTT 965

Query: 78   GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNTT 136
                G+ T TA+T     +T ++  S    A  + ++ T   + G+ T++    GT  T 
Sbjct: 966  VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTI 1025

Query: 137  SNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196
            ++  GS +      ++ T A + TT  +   TG++T      ST  S      T   E  
Sbjct: 1026 TSTEGSET------TTVTTAGSETTAVYT--TGSETTT---TSTEGSETTTVSTTGSETT 1074

Query: 197  SKSLEELRLEDYQANRKGPQNQVGAG---TTTGLFGSSPATSSATG-------LFSSSTT 246
            + S  +L       +  G      AG   TT  + GS   T+S  G         SS TT
Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 247  NSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTS 306
             +     +  T F   TT   T      G  ++ TTS  S    +ATTT   G      S
Sbjct: 1135 TASTTGSEMTTVF---TTVSETTTVSTIG--SEATTS--SAAGSEATTTSTEGSETTTAS 1187

Query: 307  TIGQPST--NTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGF-----GA 359
            T G  +T  +T G    T AS  G    TA  T + T+  +  G   +TNT F       
Sbjct: 1188 TAGSETTTASTAG-SETTTASTSGSETNTACTTGSETSTPSSAG--SETNTAFIIGSEST 1244

Query: 360  VGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK------------P 407
            + ST       T+   S T+  S   T+ G     T  S  +   +K            P
Sbjct: 1245 IASTASLEPTATSLTGSETTTVSI--TASGATAASTTVSSTTFVLTKATDVSIQPITNTP 1302

Query: 408  APG--TLGTGLGAGFGTALGAGQ---ASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGF 462
              G  T GT L A     +  G    AS   +  P  G  L T   G      ++ T   
Sbjct: 1303 MSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVP--GIVLNTSGLGTSTMGASSTTSAH 1360

Query: 463  GAPQAPVALTDPNASAAQQ 481
            G      +  +P +S  Q+
Sbjct: 1361 GVRTTTGSTREPTSSTFQE 1379



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 89/396 (22%), Positives = 145/396 (36%), Gaps = 38/396 (9%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
           T S  G  T   + SG    T++   S NT      S T    + G+ +    A S +T 
Sbjct: 47  TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT 106

Query: 79  FGFGTSTGTANTLFGTASTGTSLFSSQNN--AFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136
                +  T  +  G+ +T  S  SS+    + A ++ T     G+ T++     +  T 
Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166

Query: 137 SNPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191
           ++  GS   ++F   S T  P+      TT+       T        +T  ST H   TA
Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTA 226

Query: 192 MKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251
                S++ +               +  G+ TT    GS    +S       S TN+ F 
Sbjct: 227 ASTMGSETTKV--------------STAGSETTVSTAGSETTAAST----EDSETNTAFT 268

Query: 252 YGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQP 311
                T    STTGF T      G +    +++     G  TT  +T      T+ +   
Sbjct: 269 EDSKTTT--ASTTGFETTAASTTGSEPTMASTM-----GSETTMAST--IGPETTKVSTA 319

Query: 312 STNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGT-GLFGQTNTGFGAVGSTLFGNNKL 370
           S+    +F     +      G+ T T + T   T T  + G   +     GS        
Sbjct: 320 SSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE---TTTA 376

Query: 371 TTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
           +T GS TT+A + G+ +  +   G+ T+  SI  S+
Sbjct: 377 STEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 94/395 (23%), Positives = 157/395 (39%), Gaps = 39/395 (9%)

Query: 18  GTTSTFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72
           G+ +T    TG  TT+    G+     S  GS   T    G+  T       ++  S+  
Sbjct: 340 GSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTT-----ASTEGSEAT 394

Query: 73  TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132
           T ++TG    T + T +    T + G+ + +     F     +  G+  T  S+     T
Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454

Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192
           T +T     +T+ +  G  + TA  TG+       TG +T     + ++ +T      + 
Sbjct: 455 TASTEGS-ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-----AST 508

Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252
           +  E+ ++     E    + +G +N     TT    GS   T S TGL +++T+  G   
Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSEN-----TTVSTTGSETTTVSTTGLETTTTSTEGSEM 563

Query: 253 GQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPS 312
               T  G  TT   T   G        TT+  +   G  TTT +T  S   T++     
Sbjct: 564 TTVSTT-GAETTTDSTEGSG--------TTA--ASTAGSETTTVSTADSENTTASTADSE 612

Query: 313 TNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTT 372
           T +      T  S+      T++ T+T +  G+ T     T++    V +T       +T
Sbjct: 613 TTSAS----TTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITST 668

Query: 373 FGSSTTSAPSFGT-TSGGLFGFGTNTSGNSIFGSK 406
            GS TT+  + G+ T+    G GT T   SI GS+
Sbjct: 669 EGSETTTVSATGSETTVSTEGSGTTTV--SITGSE 701



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 99/409 (24%), Positives = 158/409 (38%), Gaps = 41/409 (10%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG------------GLFGTS 66
           T ST G  T   +T G    T +   S  T     +S+T                +F T+
Sbjct: 375 TASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETT 434

Query: 67  SFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTS 125
           + S   +  +      + T TA+T     +T T+  S    A+   ++ T   N G  T+
Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494

Query: 126 SGGLFGTTNTTSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGV---ST 180
           +    G+  TT++  GS  T+ S  G    T +  G+       TG++T   +     +T
Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240
             ST+   +T +    S +  E   +  + +     +  G+ TTT     S  T+++T  
Sbjct: 555 TTSTEGSEMTTV----STTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTA- 609

Query: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300
             S TT++     +  TA   STT   T      G +    T+  S    + T    TG 
Sbjct: 610 -DSETTSASTTGSETTTA---STTSSETTTASTEGSE----TTTVSTTDSETTMVSTTGS 661

Query: 301 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGT----AFGTGTGLFGQTNTG 356
               TST G  +T        T  S  G   GT T + TG+       TG+     +  G
Sbjct: 662 ERTITSTEGSETTTVSATGSETTVSTEGS--GTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 357 FGAVGSTLFGNNKLT--TFGSSTTSAPSFG--TTSGGLFGFGTNTSGNS 401
                +++ G+   T  T GS TT+A + G  TTS    G  T T+  +
Sbjct: 720 SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 91/400 (22%), Positives = 152/400 (38%), Gaps = 24/400 (6%)

Query: 19  TTSTFGQNTGFGTTSGG-AFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77
           T  T G +T   +T G      SA GS   T    G+  T       +++ S+  T ++T
Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTV-----STTGSETTTVSTT 549

Query: 78  GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTS 137
           G    T++   + +   ++TG    +           +  G+  T+ S+     TT +T+
Sbjct: 550 GLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTA 609

Query: 138 NPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYES 197
           +   +TS S  G  + TA+ T +        G++T     VST  S      T   E   
Sbjct: 610 DS-ETTSASTTGSETTTASTTSSETTTASTEGSETTT---VSTTDSETTMVSTTGSERTI 665

Query: 198 KSLEELRLEDYQANRKGPQNQV---GAGTTT-GLFGSSPATSSATGLFSSSTTNSGFAYG 253
            S E        A   G +  V   G+GTTT  + GS     S TG  +++T+  G    
Sbjct: 666 TSTEGSETTTVSAT--GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI- 722

Query: 254 QNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPST 313
              +  G+ TT   T          + + +  +   G  TTT +T  S    ++I    T
Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSET 782

Query: 314 NTMGLFG--VTQASQPGGLFGT--ATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNK 369
                 G   T+ S       T    N+ T  A  T +     +  G   + ++  G+  
Sbjct: 783 TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 370 LTTF---GSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
            TT    GS TT+A + G+ +       + T+  +  GS+
Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 77/327 (23%), Positives = 131/327 (40%), Gaps = 38/327 (11%)

Query: 71  PATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGF--------GNFGT 122
           PA  ++T     T + T   L   + T T+  S+  +      PTG         G+  T
Sbjct: 9   PAAGSNTTTASTTGSETTTILIKASETTTA--STAGSETTTPSPTGSQTTIVSISGSEIT 66

Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182
           +TS+ G   TT +++   G+T+ S+ G S  T +  G+       TGT+T + + + +  
Sbjct: 67  TTSTAGSENTTVSSAGS-GTTTASMAG-SETTVSTAGSETTTVSITGTETTMVSAMGSET 124

Query: 183 STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFS 242
           +T            S +  E  +     +     + VG+ TTT     S  T+++T    
Sbjct: 125 TT-----------NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSE 173

Query: 243 SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302
            +T  +  +     +  G+ TT   T           +TT++ +   G  TTT +T  S 
Sbjct: 174 MTTVFTAGSETITPSTAGSETTTVST--------AGSETTTVSTT--GSETTTASTAHSE 223

Query: 303 GN-TSTIGQPSTNTMGLFGVTQASQPGGLFGTAT--NTSTGTAFGTGTGLFGQTNTGFGA 359
               ST+G  +T        T  S  G     A+  ++ T TAF   +     + TGF  
Sbjct: 224 TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFET 283

Query: 360 VGSTLFGN--NKLTTFGSSTTSAPSFG 384
             ++  G+     +T GS TT A + G
Sbjct: 284 TAASTTGSEPTMASTMGSETTMASTIG 310



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 68/286 (23%), Positives = 102/286 (35%), Gaps = 48/286 (16%)

Query: 131 GTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC 188
           G+  TT++  GS + ++   +S   TA+  G+      PTG+ T + +   + I+T    
Sbjct: 12  GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTS-- 69

Query: 189 ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248
            TA  E  + S                    G+GTTT     S  T S  G  S +TT  
Sbjct: 70  -TAGSENTTVS------------------SAGSGTTTASMAGSETTVSTAG--SETTT-- 106

Query: 249 GFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTI 308
                        S TG  T      G +    T+  S    + T T   G      ST+
Sbjct: 107 ------------VSITGTETTMVSAMGSE----TTTNSTTSSETTVTSTAGSETTTVSTV 150

Query: 309 GQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNN 368
           G  +T        T A+   G   T   T+        T   G   T     GS      
Sbjct: 151 GSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTA--GSETTTVSTAGSE---TT 205

Query: 369 KLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGT 414
            ++T GS TT+A +  + +      G+ T+  S  GS+    T G+
Sbjct: 206 TVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS 251


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 141/556 (25%), Positives = 215/556 (38%), Gaps = 69/556 (12%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTS 76
            TTST G  T   +T G    T++  SS  T      S+T      G  T++ S   + T+
Sbjct: 845  TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 77   TGFGFG------TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF-----GTSTS 125
            T    G      ++TG+  T   T  + T+  S++ +       TG         G+ T+
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 126  SGGLFGTTNTTSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIS 183
            +    G+  TT++  GS  T+ S  G  + TA+  G+       TG++T   +   T  +
Sbjct: 965  TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024

Query: 184  TKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSS 243
                 IT+ +  E+ ++     E       G +      TTT   GS   T S TG   S
Sbjct: 1025 -----ITSTEGSETTTVTTAGSETTAVYTTGSET-----TTTSTEGSETTTVSTTG---S 1071

Query: 244  STTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFG 303
             TT +  A  +  T    ST+G GT      G    +TT+++    G  TTT +T  S  
Sbjct: 1072 ETTTASTADLETTT---VSTSGSGTTTASTAG---SETTTVYIT--GSKTTTASTEGSEA 1123

Query: 304  NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363
             T +     T T      T  S+   +F T + T+T +  G+       T++  G+  +T
Sbjct: 1124 TTVSTTSSETTTAS----TTGSEMTTVFTTVSETTTVSTIGSE----ATTSSAAGSEATT 1175

Query: 364  LFGNNKLTTFGSSTTSAPSFG--TTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFG 421
                   +T GS TT+A + G  TT+    G  T T+  S   +  A  T     G+   
Sbjct: 1176 ------TSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTT-----GSETS 1224

Query: 422  TALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQ 481
            T   AG  +    N   I G   T A  A      TAT   G+    V++T   A+AA  
Sbjct: 1225 TPSSAGSET----NTAFIIGSESTIASTAS--LEPTATSLTGSETTTVSITASGATAAST 1278

Query: 482  AVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPAT 541
             V          +     P+   PMS  +    RL      A  ++T       T   A+
Sbjct: 1279 TVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRL-----TASSSVTMAPGMDFTASAAS 1333

Query: 542  RVRPK-ALQTTGTAKS 556
               P   L T+G   S
Sbjct: 1334 HTVPGIVLNTSGLGTS 1349



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 124/499 (24%), Positives = 182/499 (36%), Gaps = 64/499 (12%)

Query: 18   GTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77
            G+  T    TG  TT+    G+    +S     L   S T       T + S   + T+T
Sbjct: 910  GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS----ETITVSAEGSETTT 965

Query: 78   GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNTT 136
                G+ T TA+T     +T ++  S    A  + ++ T   + G+ T++    GT  T 
Sbjct: 966  VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTI 1025

Query: 137  SNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196
            ++  GS +      ++ T A + TT  +   TG++T      ST  S      T   E  
Sbjct: 1026 TSTEGSET------TTVTTAGSETTAVYT--TGSETTT---TSTEGSETTTVSTTGSETT 1074

Query: 197  SKSLEELRLEDYQANRKGPQNQVGAG---TTTGLFGSSPATSSATG-------LFSSSTT 246
            + S  +L       +  G      AG   TT  + GS   T+S  G         SS TT
Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 247  NSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTS 306
             +     +  T F   TT   T      G  ++ TTS  S    +ATTT   G      S
Sbjct: 1135 TASTTGSEMTTVF---TTVSETTTVSTIG--SEATTS--SAAGSEATTTSTEGSETTTAS 1187

Query: 307  TIGQPST--NTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGF-----GA 359
            T G  +T  +T G    T AS  G    TA  T + T+  +  G   +TNT F       
Sbjct: 1188 TAGSETTTASTAG-SETTTASTSGSETNTACTTGSETSTPSSAG--SETNTAFIIGSEST 1244

Query: 360  VGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK------------P 407
            + ST       T+   S T+  S   T+ G     T  S  +   +K            P
Sbjct: 1245 IASTASLEPTATSLTGSETTTVSI--TASGATAASTTVSSTTFVLTKATDVSIQPITNTP 1302

Query: 408  APG--TLGTGLGAGFGTALGAGQ---ASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGF 462
              G  T GT L A     +  G    AS   +  P  G  L T   G      ++ T   
Sbjct: 1303 MSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVP--GIVLNTSGLGTSTMGASSTTSAH 1360

Query: 463  GAPQAPVALTDPNASAAQQ 481
            G      +  +P +S  Q+
Sbjct: 1361 GVRTTTGSTREPTSSTFQE 1379



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 89/396 (22%), Positives = 145/396 (36%), Gaps = 38/396 (9%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
           T S  G  T   + SG    T++   S NT      S T    + G+ +    A S +T 
Sbjct: 47  TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT 106

Query: 79  FGFGTSTGTANTLFGTASTGTSLFSSQNN--AFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136
                +  T  +  G+ +T  S  SS+    + A ++ T     G+ T++     +  T 
Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166

Query: 137 SNPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191
           ++  GS   ++F   S T  P+      TT+       T        +T  ST H   TA
Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTA 226

Query: 192 MKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251
                S++ +               +  G+ TT    GS    +S       S TN+ F 
Sbjct: 227 ASTMGSETTKV--------------STAGSETTVSTAGSETTAAST----EDSETNTAFT 268

Query: 252 YGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQP 311
                T    STTGF T      G +    +++     G  TT  +T      T+ +   
Sbjct: 269 EDSKTTT--ASTTGFETTAASTTGSEPTMASTM-----GSETTMAST--IGPETTKVSTA 319

Query: 312 STNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGT-GLFGQTNTGFGAVGSTLFGNNKL 370
           S+    +F     +      G+ T T + T   T T  + G   +     GS        
Sbjct: 320 SSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE---TTTA 376

Query: 371 TTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
           +T GS TT+A + G+ +  +   G+ T+  SI  S+
Sbjct: 377 STEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 94/395 (23%), Positives = 157/395 (39%), Gaps = 39/395 (9%)

Query: 18  GTTSTFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72
           G+ +T    TG  TT+    G+     S  GS   T    G+  T       ++  S+  
Sbjct: 340 GSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTT-----ASTEGSEAT 394

Query: 73  TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132
           T ++TG    T + T +    T + G+ + +     F     +  G+  T  S+     T
Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454

Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192
           T +T     +T+ +  G  + TA  TG+       TG +T     + ++ +T      + 
Sbjct: 455 TASTEGS-ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-----AST 508

Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252
           +  E+ ++     E    + +G +N     TT    GS   T S TGL +++T+  G   
Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSEN-----TTVSTTGSETTTVSTTGLETTTTSTEGSEM 563

Query: 253 GQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPS 312
               T  G  TT   T   G        TT+  +   G  TTT +T  S   T++     
Sbjct: 564 TTVSTT-GAETTTDSTEGSG--------TTA--ASTAGSETTTVSTADSENTTASTADSE 612

Query: 313 TNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTT 372
           T +      T  S+      T++ T+T +  G+ T     T++    V +T       +T
Sbjct: 613 TTSAS----TTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITST 668

Query: 373 FGSSTTSAPSFGT-TSGGLFGFGTNTSGNSIFGSK 406
            GS TT+  + G+ T+    G GT T   SI GS+
Sbjct: 669 EGSETTTVSATGSETTVSTEGSGTTTV--SITGSE 701



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 99/409 (24%), Positives = 158/409 (38%), Gaps = 41/409 (10%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG------------GLFGTS 66
           T ST G  T   +T G    T +   S  T     +S+T                +F T+
Sbjct: 375 TASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETT 434

Query: 67  SFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTS 125
           + S   +  +      + T TA+T     +T T+  S    A+   ++ T   N G  T+
Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494

Query: 126 SGGLFGTTNTTSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGV---ST 180
           +    G+  TT++  GS  T+ S  G    T +  G+       TG++T   +     +T
Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240
             ST+   +T +    S +  E   +  + +     +  G+ TTT     S  T+++T  
Sbjct: 555 TTSTEGSEMTTV----STTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTA- 609

Query: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300
             S TT++     +  TA   STT   T      G +    T+  S    + T    TG 
Sbjct: 610 -DSETTSASTTGSETTTA---STTSSETTTASTEGSE----TTTVSTTDSETTMVSTTGS 661

Query: 301 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGT----AFGTGTGLFGQTNTG 356
               TST G  +T        T  S  G   GT T + TG+       TG+     +  G
Sbjct: 662 ERTITSTEGSETTTVSATGSETTVSTEGS--GTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 357 FGAVGSTLFGNNKLT--TFGSSTTSAPSFG--TTSGGLFGFGTNTSGNS 401
                +++ G+   T  T GS TT+A + G  TTS    G  T T+  +
Sbjct: 720 SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 91/400 (22%), Positives = 152/400 (38%), Gaps = 24/400 (6%)

Query: 19  TTSTFGQNTGFGTTSGG-AFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77
           T  T G +T   +T G      SA GS   T    G+  T       +++ S+  T ++T
Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTV-----STTGSETTTVSTT 549

Query: 78  GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTS 137
           G    T++   + +   ++TG    +           +  G+  T+ S+     TT +T+
Sbjct: 550 GLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTA 609

Query: 138 NPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYES 197
           +   +TS S  G  + TA+ T +        G++T     VST  S      T   E   
Sbjct: 610 DS-ETTSASTTGSETTTASTTSSETTTASTEGSETTT---VSTTDSETTMVSTTGSERTI 665

Query: 198 KSLEELRLEDYQANRKGPQNQV---GAGTTT-GLFGSSPATSSATGLFSSSTTNSGFAYG 253
            S E        A   G +  V   G+GTTT  + GS     S TG  +++T+  G    
Sbjct: 666 TSTEGSETTTVSAT--GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI- 722

Query: 254 QNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPST 313
              +  G+ TT   T          + + +  +   G  TTT +T  S    ++I    T
Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSET 782

Query: 314 NTMGLFG--VTQASQPGGLFGT--ATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNK 369
                 G   T+ S       T    N+ T  A  T +     +  G   + ++  G+  
Sbjct: 783 TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 370 LTTF---GSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
            TT    GS TT+A + G+ +       + T+  +  GS+
Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 77/327 (23%), Positives = 131/327 (40%), Gaps = 38/327 (11%)

Query: 71  PATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGF--------GNFGT 122
           PA  ++T     T + T   L   + T T+  S+  +      PTG         G+  T
Sbjct: 9   PAAGSNTTTASTTGSETTTILIKASETTTA--STAGSETTTPSPTGSQTTIVSISGSEIT 66

Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182
           +TS+ G   TT +++   G+T+ S+ G S  T +  G+       TGT+T + + + +  
Sbjct: 67  TTSTAGSENTTVSSAGS-GTTTASMAG-SETTVSTAGSETTTVSITGTETTMVSAMGSET 124

Query: 183 STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFS 242
           +T            S +  E  +     +     + VG+ TTT     S  T+++T    
Sbjct: 125 TT-----------NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSE 173

Query: 243 SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302
            +T  +  +     +  G+ TT   T           +TT++ +   G  TTT +T  S 
Sbjct: 174 MTTVFTAGSETITPSTAGSETTTVST--------AGSETTTVSTT--GSETTTASTAHSE 223

Query: 303 GN-TSTIGQPSTNTMGLFGVTQASQPGGLFGTAT--NTSTGTAFGTGTGLFGQTNTGFGA 359
               ST+G  +T        T  S  G     A+  ++ T TAF   +     + TGF  
Sbjct: 224 TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFET 283

Query: 360 VGSTLFGN--NKLTTFGSSTTSAPSFG 384
             ++  G+     +T GS TT A + G
Sbjct: 284 TAASTTGSEPTMASTMGSETTMASTIG 310



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 68/286 (23%), Positives = 102/286 (35%), Gaps = 48/286 (16%)

Query: 131 GTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC 188
           G+  TT++  GS + ++   +S   TA+  G+      PTG+ T + +   + I+T    
Sbjct: 12  GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTS-- 69

Query: 189 ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248
            TA  E  + S                    G+GTTT     S  T S  G  S +TT  
Sbjct: 70  -TAGSENTTVS------------------SAGSGTTTASMAGSETTVSTAG--SETTT-- 106

Query: 249 GFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTI 308
                        S TG  T      G +    T+  S    + T T   G      ST+
Sbjct: 107 ------------VSITGTETTMVSAMGSE----TTTNSTTSSETTVTSTAGSETTTVSTV 150

Query: 309 GQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNN 368
           G  +T        T A+   G   T   T+        T   G   T     GS      
Sbjct: 151 GSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTA--GSETTTVSTAGSE---TT 205

Query: 369 KLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGT 414
            ++T GS TT+A +  + +      G+ T+  S  GS+    T G+
Sbjct: 206 TVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS 251


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 82.8 bits (203), Expect = 3e-15
 Identities = 141/556 (25%), Positives = 215/556 (38%), Gaps = 69/556 (12%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTS 76
            TTST G  T   +T G    T++  SS  T      S+T      G  T++ S   + T+
Sbjct: 845  TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 77   TGFGFG------TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF-----GTSTS 125
            T    G      ++TG+  T   T  + T+  S++ +       TG         G+ T+
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 126  SGGLFGTTNTTSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIS 183
            +    G+  TT++  GS  T+ S  G  + TA+  G+       TG++T   +   T  +
Sbjct: 965  TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024

Query: 184  TKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSS 243
                 IT+ +  E+ ++     E       G +      TTT   GS   T S TG   S
Sbjct: 1025 -----ITSTEGSETTTVTTAGSETTAVYTTGSET-----TTTSTEGSETTTVSTTG---S 1071

Query: 244  STTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFG 303
             TT +  A  +  T    ST+G GT      G    +TT+++    G  TTT +T  S  
Sbjct: 1072 ETTTASTADLETTT---VSTSGSGTTTASTAG---SETTTVYIT--GSKTTTASTEGSEA 1123

Query: 304  NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363
             T +     T T      T  S+   +F T + T+T +  G+       T++  G+  +T
Sbjct: 1124 TTVSTTSSETTTAS----TTGSEMTTVFTTVSETTTVSTIGSE----ATTSSAAGSEATT 1175

Query: 364  LFGNNKLTTFGSSTTSAPSFG--TTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFG 421
                   +T GS TT+A + G  TT+    G  T T+  S   +  A  T     G+   
Sbjct: 1176 ------TSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTT-----GSETS 1224

Query: 422  TALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQ 481
            T   AG  +    N   I G   T A  A      TAT   G+    V++T   A+AA  
Sbjct: 1225 TPSSAGSET----NTAFIIGSETTIASTAS--LEPTATSLTGSETTTVSITASGATAAST 1278

Query: 482  AVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPAT 541
             V          +     P+   PMS  +    RL      A  ++T       T   A+
Sbjct: 1279 TVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRL-----TASSSVTMAPGMDFTASAAS 1333

Query: 542  RVRPK-ALQTTGTAKS 556
               P   L T+G   S
Sbjct: 1334 HTVPGIVLNTSGLGTS 1349



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 89/396 (22%), Positives = 145/396 (36%), Gaps = 38/396 (9%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
           T S  G  T   + SG    T++   S NT      S T    + G+ +    A S +T 
Sbjct: 47  TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT 106

Query: 79  FGFGTSTGTANTLFGTASTGTSLFSSQNN--AFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136
                +  T  +  G+ +T  S  SS+    + A ++ T     G+ T++     +  T 
Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166

Query: 137 SNPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191
           ++  GS   ++F   S T  P+      TT+       T        +T  ST H   TA
Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTA 226

Query: 192 MKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251
                S++ +               +  G+ TT    GS    +S       S TN+ F 
Sbjct: 227 ASTMGSETTKV--------------STAGSETTVSTAGSETTAAST----EDSETNTAFT 268

Query: 252 YGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQP 311
                T    STTGF T      G +    +++     G  TT  +T      T+ +   
Sbjct: 269 EDSKTTT--ASTTGFETTAASTTGSEPTMASTM-----GSETTMAST--IGPETTKVSTA 319

Query: 312 STNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGT-GLFGQTNTGFGAVGSTLFGNNKL 370
           S+    +F     +      G+ T T + T   T T  + G   +     GS        
Sbjct: 320 SSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE---TTTA 376

Query: 371 TTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
           +T GS TT+A + G+ +  +   G+ T+  SI  S+
Sbjct: 377 STEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 124/498 (24%), Positives = 184/498 (36%), Gaps = 62/498 (12%)

Query: 18   GTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77
            G+  T    TG  TT+    G+    +S     L   S T       T + S   + T+T
Sbjct: 910  GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS----ETITVSAEGSETTT 965

Query: 78   GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNTT 136
                G+ T TA+T     +T ++  S    A  + ++ T   + G+ T++    GT  T 
Sbjct: 966  VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTI 1025

Query: 137  SNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196
            ++  GS +      ++ T A + TT  +   TG++T      ST  S      T   E  
Sbjct: 1026 TSTEGSET------TTVTTAGSETTAVYT--TGSETTT---TSTEGSETTTVSTTGSETT 1074

Query: 197  SKSLEELRLEDYQANRKGPQNQVGAG---TTTGLFGSSPATSSATG-------LFSSSTT 246
            + S  +L       +  G      AG   TT  + GS   T+S  G         SS TT
Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 247  NSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTS 306
             +     +  T F   TT   T      G  ++ TTS  S    +ATTT   G      S
Sbjct: 1135 TASTTGSEMTTVF---TTVSETTTVSTIG--SEATTS--SAAGSEATTTSTEGSETTTAS 1187

Query: 307  TIGQPST--NTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGS-- 362
            T G  +T  +T G    T AS  G    TA  T + T+  +  G   +TNT F  +GS  
Sbjct: 1188 TAGSETTTASTAG-SETTTASTSGSETNTACTTGSETSTPSSAG--SETNTAF-IIGSET 1243

Query: 363  ------------TLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSI--FGSKPA 408
                        T    ++ TT   + + A +  TT        T  +  SI    + P 
Sbjct: 1244 TIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPM 1303

Query: 409  PG--TLGTGLGAGFGTALGAGQ---ASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG 463
             G  T GT L A     +  G    AS   +  P  G  L T   G      ++ T   G
Sbjct: 1304 SGTRTTGTRLTASSSVTMAPGMDFTASAASHTVP--GIVLNTSGLGTSTMGASSTTSAHG 1361

Query: 464  APQAPVALTDPNASAAQQ 481
                  +  +P +S  Q+
Sbjct: 1362 VRTTTGSTREPTSSTFQE 1379



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 94/395 (23%), Positives = 157/395 (39%), Gaps = 39/395 (9%)

Query: 18  GTTSTFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72
           G+ +T    TG  TT+    G+     S  GS   T    G+  T       ++  S+  
Sbjct: 340 GSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTT-----ASTEGSEAT 394

Query: 73  TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132
           T ++TG    T + T +    T + G+ + +     F     +  G+  T  S+     T
Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454

Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192
           T +T     +T+ +  G  + TA  TG+       TG +T     + ++ +T      + 
Sbjct: 455 TASTEGS-ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-----AST 508

Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252
           +  E+ ++     E    + +G +N     TT    GS   T S TGL +++T+  G   
Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSEN-----TTVSTTGSETTTVSTTGLETTTTSTEGSEM 563

Query: 253 GQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPS 312
               T  G  TT   T   G        TT+  +   G  TTT +T  S   T++     
Sbjct: 564 TTVSTT-GAETTTDSTEGSG--------TTA--ASTAGSETTTVSTADSENTTASTADSE 612

Query: 313 TNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTT 372
           T +      T  S+      T++ T+T +  G+ T     T++    V +T       +T
Sbjct: 613 TTSAS----TTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITST 668

Query: 373 FGSSTTSAPSFGT-TSGGLFGFGTNTSGNSIFGSK 406
            GS TT+  + G+ T+    G GT T   SI GS+
Sbjct: 669 EGSETTTVSATGSETTVSTEGSGTTTV--SITGSE 701



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 99/409 (24%), Positives = 158/409 (38%), Gaps = 41/409 (10%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG------------GLFGTS 66
           T ST G  T   +T G    T +   S  T     +S+T                +F T+
Sbjct: 375 TASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETT 434

Query: 67  SFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTS 125
           + S   +  +      + T TA+T     +T T+  S    A+   ++ T   N G  T+
Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494

Query: 126 SGGLFGTTNTTSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGV---ST 180
           +    G+  TT++  GS  T+ S  G    T +  G+       TG++T   +     +T
Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 554

Query: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240
             ST+   +T +    S +  E   +  + +     +  G+ TTT     S  T+++T  
Sbjct: 555 TTSTEGSEMTTV----STTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTA- 609

Query: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300
             S TT++     +  TA   STT   T      G +    T+  S    + T    TG 
Sbjct: 610 -DSETTSASTTGSETTTA---STTSSETTTASTEGSE----TTTVSTTDSETTMVSTTGS 661

Query: 301 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGT----AFGTGTGLFGQTNTG 356
               TST G  +T        T  S  G   GT T + TG+       TG+     +  G
Sbjct: 662 ERTITSTEGSETTTVSATGSETTVSTEGS--GTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 357 FGAVGSTLFGNNKLT--TFGSSTTSAPSFG--TTSGGLFGFGTNTSGNS 401
                +++ G+   T  T GS TT+A + G  TTS    G  T T+  +
Sbjct: 720 SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 768



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 91/400 (22%), Positives = 152/400 (38%), Gaps = 24/400 (6%)

Query: 19  TTSTFGQNTGFGTTSGG-AFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77
           T  T G +T   +T G      SA GS   T    G+  T       +++ S+  T ++T
Sbjct: 495 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTV-----STTGSETTTVSTT 549

Query: 78  GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTS 137
           G    T++   + +   ++TG    +           +  G+  T+ S+     TT +T+
Sbjct: 550 GLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTA 609

Query: 138 NPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYES 197
           +   +TS S  G  + TA+ T +        G++T     VST  S      T   E   
Sbjct: 610 DS-ETTSASTTGSETTTASTTSSETTTASTEGSETTT---VSTTDSETTMVSTTGSERTI 665

Query: 198 KSLEELRLEDYQANRKGPQNQV---GAGTTT-GLFGSSPATSSATGLFSSSTTNSGFAYG 253
            S E        A   G +  V   G+GTTT  + GS     S TG  +++T+  G    
Sbjct: 666 TSTEGSETTTVSAT--GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI- 722

Query: 254 QNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPST 313
              +  G+ TT   T          + + +  +   G  TTT +T  S    ++I    T
Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSET 782

Query: 314 NTMGLFG--VTQASQPGGLFGT--ATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNK 369
                 G   T+ S       T    N+ T  A  T +     +  G   + ++  G+  
Sbjct: 783 TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 370 LTTF---GSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
            TT    GS TT+A + G+ +       + T+  +  GS+
Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 882



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 77/327 (23%), Positives = 131/327 (40%), Gaps = 38/327 (11%)

Query: 71  PATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGF--------GNFGT 122
           PA  ++T     T + T   L   + T T+  S+  +      PTG         G+  T
Sbjct: 9   PAAGSNTTTASTTGSETTTILIKASETTTA--STAGSETTTPSPTGSQTTIVSISGSEIT 66

Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182
           +TS+ G   TT +++   G+T+ S+ G S  T +  G+       TGT+T + + + +  
Sbjct: 67  TTSTAGSENTTVSSAGS-GTTTASMAG-SETTVSTAGSETTTVSITGTETTMVSAMGSET 124

Query: 183 STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFS 242
           +T            S +  E  +     +     + VG+ TTT     S  T+++T    
Sbjct: 125 TT-----------NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSE 173

Query: 243 SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302
            +T  +  +     +  G+ TT   T           +TT++ +   G  TTT +T  S 
Sbjct: 174 MTTVFTAGSETITPSTAGSETTTVST--------AGSETTTVSTT--GSETTTASTAHSE 223

Query: 303 GN-TSTIGQPSTNTMGLFGVTQASQPGGLFGTAT--NTSTGTAFGTGTGLFGQTNTGFGA 359
               ST+G  +T        T  S  G     A+  ++ T TAF   +     + TGF  
Sbjct: 224 TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFET 283

Query: 360 VGSTLFGN--NKLTTFGSSTTSAPSFG 384
             ++  G+     +T GS TT A + G
Sbjct: 284 TAASTTGSEPTMASTMGSETTMASTIG 310



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 68/286 (23%), Positives = 102/286 (35%), Gaps = 48/286 (16%)

Query: 131 GTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC 188
           G+  TT++  GS + ++   +S   TA+  G+      PTG+ T + +   + I+T    
Sbjct: 12  GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTS-- 69

Query: 189 ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248
            TA  E  + S                    G+GTTT     S  T S  G  S +TT  
Sbjct: 70  -TAGSENTTVS------------------SAGSGTTTASMAGSETTVSTAG--SETTT-- 106

Query: 249 GFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTI 308
                        S TG  T      G +    T+  S    + T T   G      ST+
Sbjct: 107 ------------VSITGTETTMVSAMGSE----TTTNSTTSSETTVTSTAGSETTTVSTV 150

Query: 309 GQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNN 368
           G  +T        T A+   G   T   T+        T   G   T     GS      
Sbjct: 151 GSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTA--GSETTTVSTAGSE---TT 205

Query: 369 KLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGT 414
            ++T GS TT+A +  + +      G+ T+  S  GS+    T G+
Sbjct: 206 TVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS 251


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 82.8 bits (203), Expect = 3e-15
 Identities = 141/556 (25%), Positives = 215/556 (38%), Gaps = 69/556 (12%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTS 76
            TTST G  T   +T G    T++  SS  T      S+T      G  T++ S   + T+
Sbjct: 866  TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 925

Query: 77   TGFGFG------TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNF-----GTSTS 125
            T    G      ++TG+  T   T  + T+  S++ +       TG         G+ T+
Sbjct: 926  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 985

Query: 126  SGGLFGTTNTTSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIS 183
            +    G+  TT++  GS  T+ S  G  + TA+  G+       TG++T   +   T  +
Sbjct: 986  TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1045

Query: 184  TKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSS 243
                 IT+ +  E+ ++     E       G +      TTT   GS   T S TG   S
Sbjct: 1046 -----ITSTEGSETTTVTTAGSETTAVYTTGSET-----TTTSTEGSETTTVSTTG---S 1092

Query: 244  STTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFG 303
             TT +  A  +  T    ST+G GT      G    +TT+++    G  TTT +T  S  
Sbjct: 1093 ETTTASTADLETTT---VSTSGSGTTTASTAG---SETTTVYIT--GSKTTTASTEGSEA 1144

Query: 304  NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363
             T +     T T      T  S+   +F T + T+T +  G+       T++  G+  +T
Sbjct: 1145 TTVSTTSSETTTAS----TTGSEMTTVFTTVSETTTVSTIGSE----ATTSSAAGSEATT 1196

Query: 364  LFGNNKLTTFGSSTTSAPSFG--TTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFG 421
                   +T GS TT+A + G  TT+    G  T T+  S   +  A  T     G+   
Sbjct: 1197 ------TSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTT-----GSETS 1245

Query: 422  TALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQ 481
            T   AG  +    N   I G   T A  A      TAT   G+    V++T   A+AA  
Sbjct: 1246 TPSSAGSET----NTAFIIGSETTIASTAS--LEPTATSLTGSETTTVSITASGATAAST 1299

Query: 482  AVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPAT 541
             V          +     P+   PMS  +    RL      A  ++T       T   A+
Sbjct: 1300 TVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRL-----TASSSVTMAPGMDFTASAAS 1354

Query: 542  RVRPK-ALQTTGTAKS 556
               P   L T+G   S
Sbjct: 1355 HTVPGIVLNTSGLGTS 1370



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 94/397 (23%), Positives = 147/397 (37%), Gaps = 40/397 (10%)

Query: 19  TTSTFGQNTGFGTTSGGAFGT-SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77
           T S  G  T   + SG    T S  GS N T    G+  T        S+ S   + T+T
Sbjct: 68  TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGSETTT 127

Query: 78  GFGFGTSTGTANTLFGTASTGTSLFSSQN--NAFAQNKPTGFGNFGTSTSSGGLFGTTNT 135
               GT T T  +  G+ +T  S  SS+    + A ++ T     G+ T++     +  T
Sbjct: 128 VSITGTET-TMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT 186

Query: 136 TSNPFGSTSGSLFGPSSFTAAPT-----GTTIKFNPPTGTDTMVKAGVSTNISTKHQCIT 190
            ++  GS   ++F   S T  P+      TT+       T        +T  ST H   T
Sbjct: 187 AASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETT 246

Query: 191 AMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGF 250
           A     S++ +               +  G+ TT    GS    +S       S TN+ F
Sbjct: 247 AASTMGSETTK--------------VSTAGSETTVSTAGSETTAAST----EDSETNTAF 288

Query: 251 AYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQ 310
                 T    STTGF T      G +    +++     G  TT  +T      T+ +  
Sbjct: 289 TEDSKTTT--ASTTGFETTAASTTGSEPTMASTM-----GSETTMAST--IGPETTKVST 339

Query: 311 PSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGT-GLFGQTNTGFGAVGSTLFGNNK 369
            S+    +F     +      G+ T T + T   T T  + G   +     GS       
Sbjct: 340 ASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE---TTT 396

Query: 370 LTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
            +T GS TT+A + G+ +  +   G+ T+  SI  S+
Sbjct: 397 ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 433



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 124/498 (24%), Positives = 184/498 (36%), Gaps = 62/498 (12%)

Query: 18   GTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77
            G+  T    TG  TT+    G+    +S     L   S T       T + S   + T+T
Sbjct: 931  GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS----ETITVSAEGSETTT 986

Query: 78   GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNTT 136
                G+ T TA+T     +T ++  S    A  + ++ T   + G+ T++    GT  T 
Sbjct: 987  VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTI 1046

Query: 137  SNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196
            ++  GS +      ++ T A + TT  +   TG++T      ST  S      T   E  
Sbjct: 1047 TSTEGSET------TTVTTAGSETTAVYT--TGSETTT---TSTEGSETTTVSTTGSETT 1095

Query: 197  SKSLEELRLEDYQANRKGPQNQVGAG---TTTGLFGSSPATSSATG-------LFSSSTT 246
            + S  +L       +  G      AG   TT  + GS   T+S  G         SS TT
Sbjct: 1096 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1155

Query: 247  NSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTS 306
             +     +  T F   TT   T      G  ++ TTS  S    +ATTT   G      S
Sbjct: 1156 TASTTGSEMTTVF---TTVSETTTVSTIG--SEATTS--SAAGSEATTTSTEGSETTTAS 1208

Query: 307  TIGQPST--NTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGS-- 362
            T G  +T  +T G    T AS  G    TA  T + T+  +  G   +TNT F  +GS  
Sbjct: 1209 TAGSETTTASTAG-SETTTASTSGSETNTACTTGSETSTPSSAG--SETNTAF-IIGSET 1264

Query: 363  ------------TLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSI--FGSKPA 408
                        T    ++ TT   + + A +  TT        T  +  SI    + P 
Sbjct: 1265 TIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPM 1324

Query: 409  PG--TLGTGLGAGFGTALGAGQ---ASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG 463
             G  T GT L A     +  G    AS   +  P  G  L T   G      ++ T   G
Sbjct: 1325 SGTRTTGTRLTASSSVTMAPGMDFTASAASHTVP--GIVLNTSGLGTSTMGASSTTSAHG 1382

Query: 464  APQAPVALTDPNASAAQQ 481
                  +  +P +S  Q+
Sbjct: 1383 VRTTTGSTREPTSSTFQE 1400



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 94/395 (23%), Positives = 157/395 (39%), Gaps = 39/395 (9%)

Query: 18  GTTSTFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72
           G+ +T    TG  TT+    G+     S  GS   T    G+  T       ++  S+  
Sbjct: 361 GSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTT-----ASTEGSEAT 415

Query: 73  TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132
           T ++TG    T + T +    T + G+ + +     F     +  G+  T  S+     T
Sbjct: 416 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 475

Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192
           T +T     +T+ +  G  + TA  TG+       TG +T     + ++ +T      + 
Sbjct: 476 TASTEGS-ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-----AST 529

Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252
           +  E+ ++     E    + +G +N     TT    GS   T S TGL +++T+  G   
Sbjct: 530 EGSETTAVSATGSEMTTVSTEGSEN-----TTVSTTGSETTTVSTTGLETTTTSTEGSEM 584

Query: 253 GQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPS 312
               T  G  TT   T   G        TT+  +   G  TTT +T  S   T++     
Sbjct: 585 TTVSTT-GAETTTDSTEGSG--------TTA--ASTAGSETTTVSTADSENTTASTADSE 633

Query: 313 TNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTT 372
           T +      T  S+      T++ T+T +  G+ T     T++    V +T       +T
Sbjct: 634 TTSAS----TTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITST 689

Query: 373 FGSSTTSAPSFGT-TSGGLFGFGTNTSGNSIFGSK 406
            GS TT+  + G+ T+    G GT T   SI GS+
Sbjct: 690 EGSETTTVSATGSETTVSTEGSGTTTV--SITGSE 722



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 99/409 (24%), Positives = 158/409 (38%), Gaps = 41/409 (10%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPG------------GLFGTS 66
           T ST G  T   +T G    T +   S  T     +S+T                +F T+
Sbjct: 396 TASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETT 455

Query: 67  SFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTS 125
           + S   +  +      + T TA+T     +T T+  S    A+   ++ T   N G  T+
Sbjct: 456 TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 515

Query: 126 SGGLFGTTNTTSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGV---ST 180
           +    G+  TT++  GS  T+ S  G    T +  G+       TG++T   +     +T
Sbjct: 516 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETT 575

Query: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240
             ST+   +T +    S +  E   +  + +     +  G+ TTT     S  T+++T  
Sbjct: 576 TTSTEGSEMTTV----STTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTA- 630

Query: 241 FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGF 300
             S TT++     +  TA   STT   T      G +    T+  S    + T    TG 
Sbjct: 631 -DSETTSASTTGSETTTA---STTSSETTTASTEGSE----TTTVSTTDSETTMVSTTGS 682

Query: 301 SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGT----AFGTGTGLFGQTNTG 356
               TST G  +T        T  S  G   GT T + TG+       TG+     +  G
Sbjct: 683 ERTITSTEGSETTTVSATGSETTVSTEGS--GTTTVSITGSETTKVSTTGSETTTTSTEG 740

Query: 357 FGAVGSTLFGNNKLT--TFGSSTTSAPSFG--TTSGGLFGFGTNTSGNS 401
                +++ G+   T  T GS TT+A + G  TTS    G  T T+  +
Sbjct: 741 SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTT 789



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 91/400 (22%), Positives = 152/400 (38%), Gaps = 24/400 (6%)

Query: 19  TTSTFGQNTGFGTTSGG-AFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77
           T  T G +T   +T G      SA GS   T    G+  T       +++ S+  T ++T
Sbjct: 516 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTV-----STTGSETTTVSTT 570

Query: 78  GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTS 137
           G    T++   + +   ++TG    +           +  G+  T+ S+     TT +T+
Sbjct: 571 GLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTA 630

Query: 138 NPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYES 197
           +   +TS S  G  + TA+ T +        G++T     VST  S      T   E   
Sbjct: 631 DS-ETTSASTTGSETTTASTTSSETTTASTEGSETTT---VSTTDSETTMVSTTGSERTI 686

Query: 198 KSLEELRLEDYQANRKGPQNQV---GAGTTT-GLFGSSPATSSATGLFSSSTTNSGFAYG 253
            S E        A   G +  V   G+GTTT  + GS     S TG  +++T+  G    
Sbjct: 687 TSTEGSETTTVSAT--GSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEI- 743

Query: 254 QNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPST 313
              +  G+ TT   T          + + +  +   G  TTT +T  S    ++I    T
Sbjct: 744 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSET 803

Query: 314 NTMGLFG--VTQASQPGGLFGT--ATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNK 369
                 G   T+ S       T    N+ T  A  T +     +  G   + ++  G+  
Sbjct: 804 TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET 863

Query: 370 LTTF---GSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
            TT    GS TT+A + G+ +       + T+  +  GS+
Sbjct: 864 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 903



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 71/297 (23%), Positives = 107/297 (36%), Gaps = 37/297 (12%)

Query: 128 GLFGTTNTTSNPFGSTSGSLFGPSSFTAAPT-GTTIKFNPPTGTDT---MVKAGVSTNIS 183
           G   TT +T++    T+ S+   S  T AP  G+       TG++T   ++KA  +T  S
Sbjct: 3   GSEATTTSTADSKVITASSM--SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTAS 60

Query: 184 TKHQCITAMKEYESKSL------EELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSA 237
           T     T      S++        E+       +     +  G+GTTT     S +T S 
Sbjct: 61  TAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTIST 120

Query: 238 TGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQN 297
            G  S +TT               S TG  T      G +    T+  S    + T T  
Sbjct: 121 AG--SETTT--------------VSITGTETTMVSAMGSE----TTTNSTTSSETTVTST 160

Query: 298 TGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGF 357
            G      ST+G  +T        T A+   G   T   T+        T   G   T  
Sbjct: 161 AGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTA--GSETTTV 218

Query: 358 GAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGT 414
              GS       ++T GS TT+A +  + +      G+ T+  S  GS+    T G+
Sbjct: 219 STAGSE---TTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS 272



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 92/399 (23%), Positives = 142/399 (35%), Gaps = 47/399 (11%)

Query: 83  TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGS 142
           T+T TA++   TAS+     SS+        P    N  T++++G    TT        +
Sbjct: 7   TTTSTADSKVITASS----MSSETTV----APAAGSNTTTASTTGS--ETTTILIKASET 56

Query: 143 TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKS 199
           T+ S  G  + T +PTG   T +  +    T T      +T +S+     T      S+S
Sbjct: 57  TTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSES 116

Query: 200 L-----EELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQ 254
                  E              + +G+ TTT    SS  T ++T    S TT       +
Sbjct: 117 TISTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTA--GSETTTVSTVGSE 174

Query: 255 NKTAF--GTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNT-STIGQP 311
             TA+   + TT   T    +       + ++     G  TTT +T  S   T ST G  
Sbjct: 175 TTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSE 234

Query: 312 STNTMGLFGVTQASQPGG-------LFGTATNTST-GTAFGTGTGLFGQTNTGFGAVGST 363
           +T        T A+   G         G+ T  ST G+     +    +TNT F     T
Sbjct: 235 TTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKT 294

Query: 364 LFGNNK--LTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFG 421
              +     TT  S+T S P+  +T G        T  ++I        T  + +   F 
Sbjct: 295 TTASTTGFETTAASTTGSEPTMASTMG-----SETTMASTIGPETTKVSTASSEVTTVFA 349

Query: 422 TALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATL 460
                 +AS  G+          T      G  TTTA++
Sbjct: 350 AGSETIRASTVGSE---------TTTVSTTGSETTTASI 379


>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
          Length = 987

 Score = 81.3 bits (199), Expect = 8e-15
 Identities = 125/442 (28%), Positives = 181/442 (40%), Gaps = 91/442 (20%)

Query: 85  TGTANTLFGTASTGTS---LFSSQNNAFAQNKPT-GFGNFGTSTSSGGLFGTTNTTSNPF 140
           T TA    G AS  ++   + S+  +  + +KP  GFG    S+SS      + TTS   
Sbjct: 537 TTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSS-----VSTTTSTAT 591

Query: 141 GSTSGSLFGP-----SSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCI-TAMKE 194
            ++   LFG      +SFT A  G+  +F  P    T      +T ++T  Q + TA+  
Sbjct: 592 AASQPFLFGAPQASAASFTPA-MGSIFQFGKPPALPT------TTTVTTFSQSLPTAVPT 644

Query: 195 YESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQ 254
             S S  +                 G G+T  L  S+PATSS   L  S+T+   F    
Sbjct: 645 ATSSSAADFS---------------GFGST--LATSAPATSSQPTLTFSNTSTPTFNIPF 687

Query: 255 NKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQ---P 311
             +A     +  G NP   FG    Q     +KP    T +  + F+FGN++       P
Sbjct: 688 GSSAKSPLPSYPGANPQPAFGAAEGQPPGA-AKP--ALTPSFGSSFTFGNSAAPAPATAP 744

Query: 312 STNTMGLFGVTQASQPGGL---FGTATNTSTGT---------------AFGTGTGLFG-- 351
           +        +  A  P  +   FG AT+++ G                AFG  T +F   
Sbjct: 745 TPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFG 804

Query: 352 -QTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTS----GGLFGFGTNTSGNSI---- 402
             T++GFGA   T    +  + FGS+T S  +FG ++     G FG    T G+S     
Sbjct: 805 AATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATTGA 864

Query: 403 --FGSKPAPGT-LGTGLGAGFG-TALG-AGQASLFGNN-------QPKIGGPLGTGAFG- 449
             FG+  +  T   T    G G  ALG  GQ++ F  N       +P  GG   T  FG 
Sbjct: 865 FSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGG-TATPTFGQ 923

Query: 450 ---APGFNTTTATLGFGAPQAP 468
              APG  T+ ++L FGA  AP
Sbjct: 924 NTPAPGVGTSGSSLSFGASSAP 945



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 115/457 (25%), Positives = 169/457 (36%), Gaps = 71/457 (15%)

Query: 69  SQPATSTSTGFGFGT-STGTANTLFGTASTGTSLFSSQNNAFAQNK-----PTGFGNFGT 122
           S P+ +    F FGT +T  ++     AS+ + +F     A  +++     P G     T
Sbjct: 429 SAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTAT 488

Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSF-------------TAAPTGTTIKF----N 165
           + SS  L  TT+TT+  F     S+  P+S                APT T   F    +
Sbjct: 489 APSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLAS 548

Query: 166 PPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRK---GPQNQVGAG 222
             +    +  A  ST+ ++K      +    S S+         A++    G      A 
Sbjct: 549 ATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAAS 608

Query: 223 TTTGL-----FGSSPA--TSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFG 275
            T  +     FG  PA  T++    FS S      A     ++     +GFG+       
Sbjct: 609 FTPAMGSIFQFGKPPALPTTTTVTTFSQSLPT---AVPTATSSSAADFSGFGSTLATSAP 665

Query: 276 QQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPS---TNTMGLFGVTQASQPGGLFG 332
             + Q T  FS      T+T      FG+++    PS    N    FG  +  QP G   
Sbjct: 666 ATSSQPTLTFSN-----TSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAE-GQPPGAAK 719

Query: 333 TATNTSTGTAFGTGTGLFGQTNTG-FGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLF 391
            A   S G++F  G        T    A  ST+    K+      T   P+FG  +   F
Sbjct: 720 PALTPSFGSSFTFGNSAAPAPATAPTPAPASTI----KIVPAHVPTPIQPTFGGATHSAF 775

Query: 392 G-------FGTNTSGNSIFGSKPAPGTLGTGLGAGFG----TALGAGQASLFGNNQPK-- 438
           G       FG   S    FG   A  + G    +GFG    TA     +S+FG+  P   
Sbjct: 776 GLKATASAFGAPASSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPF 835

Query: 439 -IGG---PLGTGAFG----APGFNTTTATLGFGAPQA 467
             GG   P G+G+FG     PG + TT    FGA Q+
Sbjct: 836 TFGGSAAPAGSGSFGINVATPGSSATTGAFSFGAGQS 872



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 122/446 (27%), Positives = 160/446 (35%), Gaps = 101/446 (22%)

Query: 6   FGTPFGGG---TGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGL 62
           FG P       T   G+   FG+     TT+     + +  ++  T     +S     G 
Sbjct: 599 FGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTAT--SSSAADFSGF 656

Query: 63  FGTSSFSQPATSTSTGFGFG-TSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFG 121
             T + S PATS+     F  TST T N  FG  S+  S   S   A   N    FG   
Sbjct: 657 GSTLATSAPATSSQPTLTFSNTSTPTFNIPFG--SSAKSPLPSYPGA---NPQPAFG--- 708

Query: 122 TSTSSGGLFGTTNTTSNP-FGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180
              + G   G       P FGS+    FG S   AAP   T     P  T  +V A V T
Sbjct: 709 --AAEGQPPGAAKPALTPSFGSSF--TFGNS---AAPAPATAPTPAPASTIKIVPAHVPT 761

Query: 181 NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFG----SSPATSS 236
            I       T                          +  G   T   FG    S PA   
Sbjct: 762 PIQPTFGGAT-------------------------HSAFGLKATASAFGAPASSQPAFGG 796

Query: 237 ATGLFS-SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTT 295
           +T +FS  + T+SGF       + G+S++ FG+            T S F+  FG +   
Sbjct: 797 STAVFSFGAATSSGFGATTQTASSGSSSSVFGST-----------TPSPFT--FGGSAAP 843

Query: 296 QNTGFSFG-NTSTIGQPSTNTMGLFGVTQASQP-------GGLFGTATNTS-TGTAFGTG 346
             +G SFG N +T G  +T     FG  Q+          GGL   A  T+   T F   
Sbjct: 844 AGSG-SFGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFN 902

Query: 347 TGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
            G   ++   FG   +  FG N         T AP  G TSG    FG +        S 
Sbjct: 903 VGSTTESKPVFGGTATPTFGQN---------TPAPGVG-TSGSSLSFGAS--------SA 944

Query: 407 PAPGTLGTGLGAGFGTA-----LGAG 427
           PA G +G G    FG+A     +GAG
Sbjct: 945 PAQGFVGVG---PFGSAAPSFSIGAG 967



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 113/504 (22%), Positives = 162/504 (32%), Gaps = 82/504 (16%)

Query: 33  SGGAFGTSAFGSSNNTGGL--FGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANT 90
           S GA  T A         L   G SQ+ P GL  + SF     +T  G     S   A  
Sbjct: 351 SAGAATTEALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATD 410

Query: 91  LFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN----PFGSTSGS 146
                +           A    KP        +     LFGT NT+ +    P  S++  
Sbjct: 411 TKAPPTL---------QAETATKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASP 461

Query: 147 LFGPSSFTAAPTGTTIKFNPP-------TGTDTMVKAGVSTNISTKHQCITAMKEYESKS 199
           +F P  FTA P        PP         + + +    ST   T     ++M    S  
Sbjct: 462 MFKPI-FTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASVP 520

Query: 200 LEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSS--STTNSGFAYGQNKT 257
           L     +        P     A   TGL  ++ A +  T    S  S +   F +G N  
Sbjct: 521 LPAPFFKQTTTPATAPTTT--APLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSV 578

Query: 258 AFG----TSTTGFGTNPGGLFGQQNQQTTSL---------FSKPFGQATTTQNTGFSFGN 304
           +      T++T    +   LFG       S          F KP    TTT  T FS   
Sbjct: 579 SSSSVSTTTSTATAASQPFLFGAPQASAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSL 638

Query: 305 TSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTG-----FGA 359
            + +   ++++   F           FG+   TS        T  F  T+T      FG+
Sbjct: 639 PTAVPTATSSSAADFSG---------FGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGS 689

Query: 360 VGSTLF----GNNKLTTFGSST-----TSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPG 410
              +      G N    FG++       + P+   + G  F FG + +        PAP 
Sbjct: 690 SAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFTFGNSAAPAPATAPTPAPA 749

Query: 411 ----------------TLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAP--- 451
                           T G    + FG    A       ++QP  GG     +FGA    
Sbjct: 750 STIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFSFGAATSS 809

Query: 452 GFNTTTATLGFGAPQAPVALTDPN 475
           GF  TT T   G+  +    T P+
Sbjct: 810 GFGATTQTASSGSSSSVFGSTTPS 833



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 91/368 (24%), Positives = 127/368 (34%), Gaps = 106/368 (28%)

Query: 5   SFGTPFGGGTG-------GFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQ- 56
           +F  PFG           G      FG   G    +     T +FGSS      FGNS  
Sbjct: 682 TFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPSFGSSFT----FGNSAA 737

Query: 57  ----TKPGGLFGTSSFSQPA---TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAF 109
               T P     ++    PA   T     FG     G  ++ FG  +T ++  +  ++  
Sbjct: 738 PAPATAPTPAPASTIKIVPAHVPTPIQPTFG-----GATHSAFGLKATASAFGAPASSQP 792

Query: 110 AQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFG---PSSFT----AAPTGTTI 162
           A    T   +FG +TSSG  FG T  T++    +S S+FG   PS FT    AAP G+  
Sbjct: 793 AFGGSTAVFSFGAATSSG--FGATTQTAS--SGSSSSVFGSTTPSPFTFGGSAAPAGS-- 846

Query: 163 KFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAG 222
                             N++T                                   G+ 
Sbjct: 847 -------------GSFGINVATP----------------------------------GSS 859

Query: 223 TTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTS--TTGFGTNPGGLFGQQNQQ 280
            TTG F      S   G   S+ T++ F  G  + A GT+  +T F  N G    +    
Sbjct: 860 ATTGAF------SFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGST-TESKPV 912

Query: 281 TTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTG 340
                +  FGQ T     G S G++ + G  S    G  GV       G FG+A      
Sbjct: 913 FGGTATPTFGQNTPAPGVGTS-GSSLSFGASSAPAQGFVGV-------GPFGSA-----A 959

Query: 341 TAFGTGTG 348
            +F  G G
Sbjct: 960 PSFSIGAG 967



 Score = 39.7 bits (91), Expect = 0.027
 Identities = 55/201 (27%), Positives = 74/201 (36%), Gaps = 29/201 (14%)

Query: 10  FGGGTG-GFGTT----------STFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTK 58
           FG  T  GFG T          S FG  T    T GG+   +  GS        G+S T 
Sbjct: 803 FGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSATT 862

Query: 59  PGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFG 118
               FG       ATST    G G +        GT    T  F+    +  ++KP  FG
Sbjct: 863 GAFSFGAGQSGSTATSTPFTGGLGQNA------LGTTGQSTP-FAFNVGSTTESKPV-FG 914

Query: 119 NFGTSTSSGGLFGTTNTTSNPFGSTSGSL-FGPSSFTAAPTGTTIKFNPPTGTDTMVKAG 177
             GT+T + G     NT +   G++  SL FG SS   AP    +   P          G
Sbjct: 915 --GTATPTFG----QNTPAPGVGTSGSSLSFGASS---APAQGFVGVGPFGSAAPSFSIG 965

Query: 178 VSTNISTKHQCITAMKEYESK 198
             +      Q + A +++  K
Sbjct: 966 AGSKTPGARQRLQARRQHTRK 986


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
            sapiens]
          Length = 1521

 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 113/473 (23%), Positives = 184/473 (38%), Gaps = 48/473 (10%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
            T ST G  T   +T+G    T++  SS  T      S+T      G+ +     T  ST 
Sbjct: 744  TASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSET-----TKVSTA 798

Query: 79   FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138
                T+  T N+    AST  S  ++ + A ++  P       T+T++    G+  TT++
Sbjct: 799  SSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTT-STEGSETTTAS 857

Query: 139  PFGS--TSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMK 193
              GS  T+ S     + TA   G   TT        T T  +   +T  ST+   IT + 
Sbjct: 858  TEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVS 917

Query: 194  E--YESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251
                E+ +      E   A+ +G +      TT    GS   T SA G  +++ T  G  
Sbjct: 918  TTGSETTTASTEGSETTTASTEGSEL-----TTVSTTGSETITVSAEGSETTTVTTMGSE 972

Query: 252  YGQNKTAFGTSTT----GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTST 307
                 TA   +TT    G  T    + G +    T+  S    + TT   TG     TST
Sbjct: 973  TTTASTAGSETTTVSTAGSETTTASIEGSE----TTTVSSTGSETTTVSTTGTETTITST 1028

Query: 308  IGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGN 367
             G  +T        T  S+   ++ T + T+T +  G+ T     T +      +     
Sbjct: 1029 EGSETTTV-----TTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLET 1083

Query: 368  NKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAG 427
              ++T GS TT+A + G+ +  ++  G+ T+  S  GS+    T+ T       T+    
Sbjct: 1084 TTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEAT--TVST-------TSSETT 1134

Query: 428  QASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQ 480
             AS  G+          T  F      TT +T+G  A  +  A ++   ++ +
Sbjct: 1135 TASTTGSEM--------TTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 102/426 (23%), Positives = 165/426 (38%), Gaps = 27/426 (6%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGT--SSFSQPATSTS 76
            T ST    T   TT G    T++   S  T      S+T      G+  ++ S   + T+
Sbjct: 865  TASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETT 924

Query: 77   TGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNT 135
            T    G+ T TA+T     +T ++  S      A+ ++ T     G+ T++    G+  T
Sbjct: 925  TASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETT 984

Query: 136  TSNPFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMV---KAGVSTNISTKHQCIT 190
            T +  GS  T+ S+ G  + T + TG+       TGT+T +   +   +T ++T     T
Sbjct: 985  TVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETT 1044

Query: 191  AMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGF 250
            A+  Y + S      E    + +G +      TT    GS   T+S   L +++ + SG 
Sbjct: 1045 AV--YTTGS------ETTTTSTEGSET-----TTVSTTGSETTTASTADLETTTVSTSGS 1091

Query: 251  AYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQ 310
                  TA   +TT + T              +  S    + TT   TG       T   
Sbjct: 1092 GTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVS 1151

Query: 311  PSTNTMGLFGVTQASQPGGLFGTATNT---STGTAFGTGTGLFGQTNTGFGAVGSTLFGN 367
             +T    +      S   G   T T+T    T TA   G+     +  G     ++  G+
Sbjct: 1152 ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGS 1211

Query: 368  --NKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTL-GTGLGAGFGTAL 424
              N   T GS T++  S G+ +   F  G+ T+  S    +P   +L G+       TA 
Sbjct: 1212 ETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITAS 1271

Query: 425  GAGQAS 430
            GA  AS
Sbjct: 1272 GATAAS 1277



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 133/559 (23%), Positives = 201/559 (35%), Gaps = 75/559 (13%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
            TTST G  T   +T G    T++  SS  T      S+T               T+ ST 
Sbjct: 845  TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---------------TTASTE 889

Query: 79   FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138
                T+T T  +   TAST  S            + T     G+ T++    G+  TT++
Sbjct: 890  GSETTTTSTEGSETTTASTEGS------------EITTVSTTGSETTTASTEGSETTTAS 937

Query: 139  PFGS--TSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196
              GS  T+ S  G  + T +  G+        G++T   +   +  +T     TA  E  
Sbjct: 938  TEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT---VSTAGSETT 994

Query: 197  SKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNK 256
            + S+E        +           GT T +  S+  + + T   + S T + +  G   
Sbjct: 995  TASIEGSETTTVSSTGSETTTVSTTGTETTI-TSTEGSETTTVTTAGSETTAVYTTGSET 1053

Query: 257  TAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTM 316
            T   TST G  T      G +    T+  S    + TT   +G      ST G   T T+
Sbjct: 1054 TT--TSTEGSETTTVSTTGSE----TTTASTADLETTTVSTSGSGTTTASTAGS-ETTTV 1106

Query: 317  GLFG--VTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFG 374
             + G   T AS  G    T + TS+ T   + TG   +  T F  V  T      ++T G
Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTG--SEMTTVFTTVSET----TTVSTIG 1160

Query: 375  SSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPG-------TLGTGLGAGFGTALGAG 427
            S  T++ + G+ +      G+ T+  S  GS+           T  +  G+   TA   G
Sbjct: 1161 SEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTG 1220

Query: 428  QASLFGNNQPKIGGPLGTGAFGAPGFNTT---------TATLGFGAPQAPVALTDPNASA 478
              +    + P   G     AF   G  TT         TAT   G+    V++T   A+A
Sbjct: 1221 SET----STPSSAGSETNTAF-IIGSETTIASTASLEPTATSLTGSETTTVSITASGATA 1275

Query: 479  AQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPR 538
            A   V          +     P+   PMS  +    RL      A  ++T       T  
Sbjct: 1276 ASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRL-----TASSSVTMAPGMDFTAS 1330

Query: 539  PATRVRPK-ALQTTGTAKS 556
             A+   P   L T+G   S
Sbjct: 1331 AASHTVPGIVLNTSGLGTS 1349



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 89/396 (22%), Positives = 145/396 (36%), Gaps = 38/396 (9%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
           T S  G  T   + SG    T++   S NT      S T    + G+ +    A S +T 
Sbjct: 47  TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTT 106

Query: 79  FGFGTSTGTANTLFGTASTGTSLFSSQNN--AFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136
                +  T  +  G+ +T  S  SS+    + A ++ T     G+ T++     +  T 
Sbjct: 107 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 166

Query: 137 SNPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191
           ++  GS   ++F   S T  P+      TT+       T        +T  ST H   TA
Sbjct: 167 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTA 226

Query: 192 MKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251
                S++ +               +  G+ TT    GS    +S       S TN+ F 
Sbjct: 227 ASTMGSETTKV--------------STAGSETTVSTAGSETTAAST----EDSETNTAFT 268

Query: 252 YGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQP 311
                T    STTGF T      G +    +++     G  TT  +T      T+ +   
Sbjct: 269 EDSKTTT--ASTTGFETTAASTTGSEPTMASTM-----GSETTMAST--IGPETTKVSTA 319

Query: 312 STNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGT-GLFGQTNTGFGAVGSTLFGNNKL 370
           S+    +F     +      G+ T T + T   T T  + G   +     GS        
Sbjct: 320 SSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSE---TTTA 376

Query: 371 TTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
           +T GS TT+A + G+ +  +   G+ T+  SI  S+
Sbjct: 377 STEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 124/498 (24%), Positives = 184/498 (36%), Gaps = 62/498 (12%)

Query: 18   GTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTST 77
            G+  T    TG  TT+    G+    +S     L   S T       T + S   + T+T
Sbjct: 910  GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGS----ETITVSAEGSETTT 965

Query: 78   GFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ-NKPTGFGNFGTSTSSGGLFGTTNTT 136
                G+ T TA+T     +T ++  S    A  + ++ T   + G+ T++    GT  T 
Sbjct: 966  VTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTI 1025

Query: 137  SNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYE 196
            ++  GS +      ++ T A + TT  +   TG++T      ST  S      T   E  
Sbjct: 1026 TSTEGSET------TTVTTAGSETTAVYT--TGSETTT---TSTEGSETTTVSTTGSETT 1074

Query: 197  SKSLEELRLEDYQANRKGPQNQVGAG---TTTGLFGSSPATSSATG-------LFSSSTT 246
            + S  +L       +  G      AG   TT  + GS   T+S  G         SS TT
Sbjct: 1075 TASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETT 1134

Query: 247  NSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTS 306
             +     +  T F   TT   T      G  ++ TTS  S    +ATTT   G      S
Sbjct: 1135 TASTTGSEMTTVF---TTVSETTTVSTIG--SEATTS--SAAGSEATTTSTEGSETTTAS 1187

Query: 307  TIGQPST--NTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGS-- 362
            T G  +T  +T G    T AS  G    TA  T + T+  +  G   +TNT F  +GS  
Sbjct: 1188 TAGSETTTASTAG-SETTTASTSGSETNTACTTGSETSTPSSAG--SETNTAF-IIGSET 1243

Query: 363  ------------TLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSI--FGSKPA 408
                        T    ++ TT   + + A +  TT        T  +  SI    + P 
Sbjct: 1244 TIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPM 1303

Query: 409  PG--TLGTGLGAGFGTALGAGQ---ASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFG 463
             G  T GT L A     +  G    AS   +  P  G  L T   G      ++ T   G
Sbjct: 1304 SGTRTTGTRLTASSSVTMAPGMDFTASAASHTVP--GIVLNTSGLGTSTMGASSTTSAHG 1361

Query: 464  APQAPVALTDPNASAAQQ 481
                  +  +P +S  Q+
Sbjct: 1362 VRTTTGSTREPTSSTFQE 1379



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 94/395 (23%), Positives = 157/395 (39%), Gaps = 39/395 (9%)

Query: 18  GTTSTFGQNTGFGTTSGGAFGT-----SAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPA 72
           G+ +T    TG  TT+    G+     S  GS   T    G+  T       ++  S+  
Sbjct: 340 GSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTT-----ASTEGSEAT 394

Query: 73  TSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGT 132
           T ++TG    T + T +    T + G+ + +     F     +  G+  T  S+     T
Sbjct: 395 TVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT 454

Query: 133 TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192
           T +T     +T+ +  G  + TA  TG+       TG +T     + ++ +T      + 
Sbjct: 455 TASTEGS-ETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTT-----AST 508

Query: 193 KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252
           +  E+ ++     E    + +G +N     TT    GS   T S TGL +++T+  G   
Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSEN-----TTVSTTGSETTTVSTTGLETTTTSTEGSEM 563

Query: 253 GQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPS 312
               T  G  TT   T   G        TT+  +   G  TTT +T  S   T++     
Sbjct: 564 TTVSTT-GAETTTDSTEGSG--------TTA--ASTAGSETTTVSTADSENTTASTADSE 612

Query: 313 TNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTT 372
           T +      T  S+      T++ T+T +  G+ T     T++    V +T       +T
Sbjct: 613 TTSAS----TTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITST 668

Query: 373 FGSSTTSAPSFGT-TSGGLFGFGTNTSGNSIFGSK 406
            GS TT+  + G+ T+    G GT T   SI GS+
Sbjct: 669 EGSETTTVSATGSETTVSTEGSGTTTV--SITGSE 701



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 101/396 (25%), Positives = 149/396 (37%), Gaps = 37/396 (9%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTS 76
           T ST G      +TS     T++   S  T      S+TK     G  T++ S     T+
Sbjct: 435 TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETT 494

Query: 77  TGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTT 136
           T F  G+ T TA+T  G+ +T  S   S+    +       G+  T+ S+ G   TT +T
Sbjct: 495 TVFTIGSDTTTASTE-GSETTAVSATGSEMTTVSTE-----GSENTTVSTTGSETTTVST 548

Query: 137 SNPFGSTSGSLFGPSSFTAAPTG--TTIKFNPPTGTDTMVKAGV-STNIST--KHQCITA 191
           +    +T+ S  G    T + TG  TT      +GT     AG  +T +ST        +
Sbjct: 549 TG-LETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAS 607

Query: 192 MKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFA 251
             + E+ S      E   A+    +      TT    GS   T S T     S T     
Sbjct: 608 TADSETTSASTTGSETTTASTTSSET-----TTASTEGSETTTVSTT----DSETTMVST 658

Query: 252 YGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQN-TGFSFGNTSTIGQ 310
            G  +T   TST G  T      G +   +T       G  TTT + TG      ST G 
Sbjct: 659 TGSERTI--TSTEGSETTTVSATGSETTVSTE------GSGTTTVSITGSETTKVSTTGS 710

Query: 311 PSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKL 370
            +T T      T+ S+      T + T+T +  G+ T       +   +  +T       
Sbjct: 711 ETTITS-----TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTA 765

Query: 371 TTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
           +T  S TT A   G+ +      G+ T+  S   SK
Sbjct: 766 STTSSETTMASIMGSETTMASTIGSETTKVSTASSK 801



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 77/327 (23%), Positives = 131/327 (40%), Gaps = 38/327 (11%)

Query: 71  PATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGF--------GNFGT 122
           PA  ++T     T + T   L   + T T+  S+  +      PTG         G+  T
Sbjct: 9   PAAGSNTTTASTTGSETTTILIKASETTTA--STAGSETTTPSPTGSQTTIVSISGSEIT 66

Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182
           +TS+ G   TT +++   G+T+ S+ G S  T +  G+       TGT+T + + + +  
Sbjct: 67  TTSTAGSENTTVSSAGS-GTTTASMAG-SETTVSTAGSETTTVSITGTETTMVSAMGSET 124

Query: 183 STKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFS 242
           +T            S +  E  +     +     + VG+ TTT     S  T+++T    
Sbjct: 125 TT-----------NSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSE 173

Query: 243 SSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSF 302
            +T  +  +     +  G+ TT   T           +TT++ +   G  TTT +T  S 
Sbjct: 174 MTTVFTAGSETITPSTAGSETTTVST--------AGSETTTVSTT--GSETTTASTAHSE 223

Query: 303 GN-TSTIGQPSTNTMGLFGVTQASQPGGLFGTAT--NTSTGTAFGTGTGLFGQTNTGFGA 359
               ST+G  +T        T  S  G     A+  ++ T TAF   +     + TGF  
Sbjct: 224 TTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFET 283

Query: 360 VGSTLFGN--NKLTTFGSSTTSAPSFG 384
             ++  G+     +T GS TT A + G
Sbjct: 284 TAASTTGSEPTMASTMGSETTMASTIG 310



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 68/286 (23%), Positives = 102/286 (35%), Gaps = 48/286 (16%)

Query: 131 GTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC 188
           G+  TT++  GS + ++   +S   TA+  G+      PTG+ T + +   + I+T    
Sbjct: 12  GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTS-- 69

Query: 189 ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNS 248
            TA  E  + S                    G+GTTT     S  T S  G  S +TT  
Sbjct: 70  -TAGSENTTVS------------------SAGSGTTTASMAGSETTVSTAG--SETTT-- 106

Query: 249 GFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTI 308
                        S TG  T      G +    T+  S    + T T   G      ST+
Sbjct: 107 ------------VSITGTETTMVSAMGSE----TTTNSTTSSETTVTSTAGSETTTVSTV 150

Query: 309 GQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNN 368
           G  +T        T A+   G   T   T+        T   G   T     GS      
Sbjct: 151 GSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTA--GSETTTVSTAGSE---TT 205

Query: 369 KLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGT 414
            ++T GS TT+A +  + +      G+ T+  S  GS+    T G+
Sbjct: 206 TVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGS 251


>gi|24430146 nucleoporin 153kDa [Homo sapiens]
          Length = 1475

 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 141/574 (24%), Positives = 212/574 (36%), Gaps = 131/574 (22%)

Query: 3    NKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGG- 61
            + SF       + G   T T   N  FG   G   G S+   S N     G   +KP G 
Sbjct: 900  SSSFKFGVSSSSSGPSQTLTSTGNFKFGDQGGFKIGVSSDSGSINPMSE-GFKFSKPIGD 958

Query: 62   -LFGTSSFSQPAT----STSTGFGFGTSTGTANTL------FGTASTGTSLFSSQNNAFA 110
              FG SS S+P      S +  F FG S+G +N +      FG ++ G      +     
Sbjct: 959  FKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVSLTPFQFGVSNLGQE---EKKEELP 1015

Query: 111  QNKPTGFGNFGT-------------------STSSGGLFGTTNTTSNPF----------- 140
            ++   GF +FGT                   S+ + G   T + +  PF           
Sbjct: 1016 KSSSAGF-SFGTGVINSTPAPANTIVTSENKSSFNLGTIETKSASVAPFTCKTSEAKKEE 1074

Query: 141  --GSTSGSLFG---PSSFTAAPT----GTTIKFNPPTGTDTMVKAGVSTNISTKHQCITA 191
               +  G  FG   P+S  +A       T  K   P  + ++V    + N   K Q + +
Sbjct: 1075 MPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTSTSLVFGKKADNEEPKCQPVFS 1134

Query: 192  MKEYESKSLEELRLEDYQANRKGPQNQ-----------VGAGTTT--------------- 225
                E    E      +  +   P  +            GA T+T               
Sbjct: 1135 FGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLN 1194

Query: 226  --GLFGSSPATSSATGLFSSSTTNSG-----FAYGQNK-----TAFGTSTTGFGTNPGGL 273
                  S+PATS+  G+F SST++S      F +GQ+      +AFG +T    T+   L
Sbjct: 1195 NSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFG-NTAESSTSQSLL 1253

Query: 274  FGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGG---L 330
            F Q ++  T+        +T T  T F FG  ++    +T+  G FG T  S   G   +
Sbjct: 1254 FSQDSKLATT-------SSTGTAVTPFVFGPGASSNNTTTSGFG-FGATTTSSSAGSSFV 1305

Query: 331  FGTATNT-STGTAFGTG-TGLFGQTN-------TGFGAVGSTLFGNNKLTTFGSSTTSAP 381
            FGT  +  S   AFG   T  FGQ+         GFG++ S+      L   GS   + P
Sbjct: 1306 FGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSS----TALFPTGSQP-APP 1360

Query: 382  SFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASL---FGNNQPK 438
            +FGT S        ++S   +FG +P+    G+G      +A   G ++    F NN P 
Sbjct: 1361 TFGTVS--------SSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPS 1412

Query: 439  IGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALT 472
                 G  +         + + GF   Q+P A T
Sbjct: 1413 GVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFT 1446



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 126/524 (24%), Positives = 188/524 (35%), Gaps = 103/524 (19%)

Query: 34   GGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFG 93
            G   G   F +S+++     +S  K G    +S  SQ  TST   F FG   G      G
Sbjct: 880  GTKSGFKGFDTSSSSSNSAASSSFKFGVSSSSSGPSQTLTSTGN-FKFGDQGGFK---IG 935

Query: 94   TASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSS------------GGLFGTTNTTSNPFG 141
             +S   S+ +  +  F  +KP G   FG S+ S               FG ++  SNP  
Sbjct: 936  VSSDSGSI-NPMSEGFKFSKPIGDFKFGVSSESKPEEVKKDSKNDNFKFGLSSGLSNPVS 994

Query: 142  STSGSLFGPSSF------TAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEY 195
             T    FG S+          P  ++  F+  TG      A  +T ++++++    +   
Sbjct: 995  LTPFQ-FGVSNLGQEEKKEELPKSSSAGFSFGTGVINSTPAPANTIVTSENKSSFNLGTI 1053

Query: 196  ESKSLE---------ELRLEDYQANRKG-----------PQNQVGAGTTTGLFGSSPATS 235
            E+KS           E + E+  A + G           P   V     T      P TS
Sbjct: 1054 ETKSASVAPFTCKTSEAKKEEMPATKGGFSFGNVEPASLPSASVFVLGRTEEKQQEPVTS 1113

Query: 236  SATGLFSSSTTNSG------FAYGQNKTA----FGTSTTGFG-TNPGGLFGQQNQQTTSL 284
            ++  +F     N        F++G ++         ST  F  T P     +Q  + T  
Sbjct: 1114 TSL-VFGKKADNEEPKCQPVFSFGNSEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFA 1172

Query: 285  FSKPFGQATTTQNTG-----FSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTST 339
            F     Q +TT + G     FSF N S+    +  T         S  GG+FG++T++S 
Sbjct: 1173 FG---AQTSTTADQGAAKPVFSFLNNSSSSSSTPAT---------SAGGGIFGSSTSSSN 1220

Query: 340  GTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSG 399
                   T +FGQ++     V S+ FGN    T  SST+ +  F   S       T T+ 
Sbjct: 1221 PPV---ATFVFGQSSN---PVSSSAFGN----TAESSTSQSLLFSQDSKLATTSSTGTAV 1270

Query: 400  NSIFGSKPAPGTLGTGLGAGFG---TALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTT 456
                    A     T  G GFG   T+  AG + +FG                  G +  
Sbjct: 1271 TPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGT-----------------GPSAP 1313

Query: 457  TATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSP 500
            +A+  FGA Q P       AS           +S    P G  P
Sbjct: 1314 SASPAFGANQTPTFGQSQGASQPNPPGFGSISSSTALFPTGSQP 1357



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 91/335 (27%), Positives = 133/335 (39%), Gaps = 52/335 (15%)

Query: 36   AFGTSAFGSSNNTGGLFGNSQTKPGGLF---GTSSFSQPATSTSTGFGFGTSTGTANTLF 92
            A  T AFG+  +T         KP   F    +SS S PATS   G  FG+ST ++N   
Sbjct: 1167 AKATFAFGAQTSTTA--DQGAAKPVFSFLNNSSSSSSTPATSAGGGI-FGSSTSSSN--- 1220

Query: 93   GTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTN----TTSNPFGSTSGSLF 148
                  T +F   +N  +    + FGN   S++S  L  + +    TTS+   + +  +F
Sbjct: 1221 --PPVATFVFGQSSNPVSS---SAFGNTAESSTSQSLLFSQDSKLATTSSTGTAVTPFVF 1275

Query: 149  GPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDY 208
            GP + +   T +   F     T T   AG S    T     +A   + +        +  
Sbjct: 1276 GPGASSNNTTTSGFGFG---ATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFG-QSQ 1331

Query: 209  QANRKGPQNQVGAGTTTGLF--GSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGF 266
             A++  P       ++T LF  GS PA  +  G  SSS+    F    +++AFG+ TT  
Sbjct: 1332 GASQPNPPGFGSISSSTALFPTGSQPAPPT-FGTVSSSSQPPVFGQQPSQSAFGSGTT-- 1388

Query: 267  GTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQA-- 324
                          ++S F   FG +T    T F+F N S  G     T G    T A  
Sbjct: 1389 ------------PNSSSAFQ--FGSST----TNFNFTNNSPSG---VFTFGANSSTPAAS 1427

Query: 325  SQPGGLFGTATNTSTG--TAFGTGTGLFGQTNTGF 357
            +QP G  G   N S    T    G  +F  + T F
Sbjct: 1428 AQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSF 1462



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 80/285 (28%), Positives = 116/285 (40%), Gaps = 49/285 (17%)

Query: 17   FGTTSTFGQNTGFGTTSGGAFGTS-----------AFGSSNN--TGGLFGN---SQTKPG 60
            F   S+   +T   +  GG FG+S            FG S+N  +   FGN   S T   
Sbjct: 1192 FLNNSSSSSSTPATSAGGGIFGSSTSSSNPPVATFVFGQSSNPVSSSAFGNTAESSTSQS 1251

Query: 61   GLFGTSSFSQPATSTSTG-----FGFGTSTGTANTL-----FGTASTGTSLFSSQNNAFA 110
             LF  S  S+ AT++STG     F FG    + NT      FG  +T +S  SS      
Sbjct: 1252 LLF--SQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTSSSAGSSFVFGTG 1309

Query: 111  QNKPTGFGNFGTSTSSGGLFGTTNTTSNP----FGSTSGS--LFGPSSFTAAPTGTTIKF 164
             + P+    FG + +    FG +   S P    FGS S S  LF   S  A PT  T+  
Sbjct: 1310 PSAPSASPAFGANQTP--TFGQSQGASQPNPPGFGSISSSTALFPTGSQPAPPTFGTVSS 1367

Query: 165  N--PPT----GTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQ 218
            +  PP      + +   +G + N S+  Q  ++   +   +     +  + AN   P   
Sbjct: 1368 SSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTFGANSSTPAAS 1427

Query: 219  VGAGTTTGL-FGSSPAT----SSATGLFSSSTTNSGFAYGQNKTA 258
                 + G  F  SPA     S+   +FSSS T+  F+  + KTA
Sbjct: 1428 AQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTS--FSGRKIKTA 1470



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 51/178 (28%), Positives = 75/178 (42%), Gaps = 38/178 (21%)

Query: 3    NKSFGTPFGGGTG----------GFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLF 52
            + S G+ F  GTG          G   T TFGQ+ G    +        FGS +++  LF
Sbjct: 1297 SSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPN-----PPGFGSISSSTALF 1351

Query: 53   GNSQTKPGGLFGT-SSFSQPAT----STSTGFGFGTSTGTANTL-FGTASTGTSLFSSQN 106
                      FGT SS SQP       + + FG GT+  +++   FG+++T        N
Sbjct: 1352 PTGSQPAPPTFGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGSSTT--------N 1403

Query: 107  NAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLF--GPSSFTAAPTGTTI 162
              F  N P+G   FG ++S      T   ++ P GS  G  F   P++FT    G  +
Sbjct: 1404 FNFTNNSPSGVFTFGANSS------TPAASAQPSGS-GGFPFNQSPAAFTVGSNGKNV 1454



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 54/186 (29%), Positives = 76/186 (40%), Gaps = 23/186 (12%)

Query: 8    TPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNT--GGLFGNSQTKPGGLFGT 65
            T  G G G   T+S+ G +  FGT       + AFG++     G   G SQ  P G    
Sbjct: 1285 TTSGFGFGATTTSSSAGSSFVFGTGPSAPSASPAFGANQTPTFGQSQGASQPNPPGFGSI 1344

Query: 66   SSF-------SQPATSTSTGFGFGT-STGTANTLFG----TASTGTSLFSSQNNAFAQNK 113
            SS        SQPA  T     FGT S+ +   +FG     ++ G+    + ++AF    
Sbjct: 1345 SSSTALFPTGSQPAPPT-----FGTVSSSSQPPVFGQQPSQSAFGSGTTPNSSSAFQFGS 1399

Query: 114  PTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTM 173
             T   NF T+ S  G+F     +S P  S   S  G   F  +P   T+  N   G +  
Sbjct: 1400 STTNFNF-TNNSPSGVFTFGANSSTPAASAQPSGSGGFPFNQSPAAFTVGSN---GKNVF 1455

Query: 174  VKAGVS 179
              +G S
Sbjct: 1456 SSSGTS 1461


>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
          Length = 984

 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 125/439 (28%), Positives = 180/439 (41%), Gaps = 88/439 (20%)

Query: 85  TGTANTLFGTASTGTS---LFSSQNNAFAQNKPT-GFGNFGTSTSSGGLFGTTNTTSNPF 140
           T TA    G AS  ++   + S+  +  + +KP  GFG    S+SS      + TTS   
Sbjct: 537 TTTAPLFTGLASATSAVAPITSASPSTDSASKPAFGFGINSVSSSS-----VSTTTSTAT 591

Query: 141 GSTSGSLFGP-----SSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCI-TAMKE 194
            ++   LFG      +SFT A  G+  +F  P    T      +T ++T  Q + TA+  
Sbjct: 592 AASQPFLFGAPQASAASFTPA-MGSIFQFGKPPALPT------TTTVTTFSQSLHTAVPT 644

Query: 195 YESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQ 254
             S S  +                 G G+T  L  S+PATSS   L  S+T+   F    
Sbjct: 645 ATSSSAADFS---------------GFGST--LATSAPATSSQPTLTFSNTSTPTFNIPF 687

Query: 255 NKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTST-IGQPST 313
             +A     +  G NP   FG    Q     +KP      +  + F+FGN++     P+ 
Sbjct: 688 GSSAKSPLPSYPGANPQPAFGAAEGQPPGA-AKP--ALAPSFGSSFTFGNSAAPAAAPTP 744

Query: 314 NTMGLFGVTQASQPGGL---FGTATNTS-----TGTAFGTGTG----LFGQTNTGFGAVG 361
               +  V  A  P  +   FG AT+++     T +AFG          G T   FGA  
Sbjct: 745 APPSMIKVVPAYVPTPIHPIFGGATHSAFGLKATASAFGAPASSQPAFGGSTAVFFGAAT 804

Query: 362 STLFG--------NNKLTTFGSSTTSAPSFGTTS----GGLFGFGTNTSGNSI------F 403
           S+ FG         +  + FGS+T S  +FG ++     G FG    T G+S       F
Sbjct: 805 SSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSTTTGAFSF 864

Query: 404 GSKPAPGT-LGTGLGAGFG-TALG-AGQASLFGNN-------QPKIGGPLGTGAFG---- 449
           G+  +  T   T    G G  ALG  GQ++ F  N       +P  GG   T  FG    
Sbjct: 865 GAGQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVSSTTESKPVFGG-TATPTFGLNTP 923

Query: 450 APGFNTTTATLGFGAPQAP 468
           APG  T+ ++L FGA  AP
Sbjct: 924 APGVGTSGSSLSFGASSAP 942



 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 118/474 (24%), Positives = 172/474 (36%), Gaps = 73/474 (15%)

Query: 69  SQPATSTSTGFGFGT-STGTANTLFGTASTGTSLFSSQNNAFAQNK-----PTGFGNFGT 122
           S P+ +    F FGT +T  ++     AS+   +F     A  +++     P G     T
Sbjct: 429 SAPSPAPKQSFLFGTQNTSPSSPAAPAASSAPPMFKPIFTAPPKSEKEGPTPPGPSVTAT 488

Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSSF-------------TAAPTGTTIKF----N 165
           + SS  L  TT+TT+  F     S+  P+S                APT T   F    +
Sbjct: 489 APSSSSLPTTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLAS 548

Query: 166 PPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRK---GPQNQVGAG 222
             +    +  A  ST+ ++K      +    S S+         A++    G      A 
Sbjct: 549 ATSAVAPITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQASAAS 608

Query: 223 TTTGL-----FGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTST---TGFGTNPGGLF 274
            T  +     FG  PA  + T    + TT S   +    TA  +S    +GFG+      
Sbjct: 609 FTPAMGSIFQFGKPPALPTTT----TVTTFSQSLHTAVPTATSSSAADFSGFGSTLATSA 664

Query: 275 GQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPS---TNTMGLFGVTQASQPGGLF 331
              + Q T  FS      T+T      FG+++    PS    N    FG  +   PG   
Sbjct: 665 PATSSQPTLTFSN-----TSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQPPG--- 716

Query: 332 GTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLF 391
             A   +   +FG+ +  FG +     A         K+      T   P FG  +   F
Sbjct: 717 --AAKPALAPSFGS-SFTFGNSAAPAAAPTPAPPSMIKVVPAYVPTPIHPIFGGATHSAF 773

Query: 392 G-------FGTNTSGNSIFGSKPA---PGTLGTGLGAGFGTALGAGQASLFGNNQPK--- 438
           G       FG   S    FG   A        +G GA   TA     +S+FG+  P    
Sbjct: 774 GLKATASAFGAPASSQPAFGGSTAVFFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFT 833

Query: 439 IGG---PLGTGAFG----APGFNTTTATLGFGAPQA-PVALTDPNASAAQQAVL 484
            GG   P G+G+FG     PG +TTT    FGA Q+   A + P A    Q  L
Sbjct: 834 FGGSAAPAGSGSFGINVATPGSSTTTGAFSFGAGQSGSTATSTPFAGGLGQNAL 887



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 106/438 (24%), Positives = 151/438 (34%), Gaps = 100/438 (22%)

Query: 6   FGTPFGGG---TGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKP--G 60
           FG P       T   G+   FG+     TT+      + F  S +T      S +     
Sbjct: 599 FGAPQASAASFTPAMGSIFQFGKPPALPTTTT----VTTFSQSLHTAVPTATSSSAADFS 654

Query: 61  GLFGTSSFSQPATSTSTGFGFG-TSTGTANTLFGTASTG---TSLFSSQNNAF--AQNKP 114
           G   T + S PATS+     F  TST T N  FG+++     +   ++   AF  A+ +P
Sbjct: 655 GFGSTLATSAPATSSQPTLTFSNTSTPTFNIPFGSSAKSPLPSYPGANPQPAFGAAEGQP 714

Query: 115 TGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMV 174
            G      + S G  F   N+ +     T      PS     P       +P  G  T  
Sbjct: 715 PGAAKPALAPSFGSSFTFGNSAAPAAAPTPAP---PSMIKVVPAYVPTPIHPIFGGATHS 771

Query: 175 KAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPAT 234
             G+    S                                    GA  +     S PA 
Sbjct: 772 AFGLKATASA----------------------------------FGAPAS-----SQPAF 792

Query: 235 SSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATT 294
             +T +F  + T+SGF       + G+S++ FG+            T S F+  FG +  
Sbjct: 793 GGSTAVFFGAATSSGFGATTQTASSGSSSSVFGST-----------TPSPFT--FGGSAA 839

Query: 295 TQNTGFSFG-NTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQT 353
              +G SFG N +T G  +T     FG  Q+         +T TST  A G G    G T
Sbjct: 840 PAGSG-SFGINVATPGSSTTTGAFSFGAGQSG--------STATSTPFAGGLGQNALGTT 890

Query: 354 --------NTGFGAVGSTLFGNNKLTTFGSSTT--------SAPSFGTTSGGLFGFGTNT 397
                   N         +FG     TFG +T         S+ SFG +S    GF    
Sbjct: 891 GQSTPFAFNVSSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASSAPAQGF---- 946

Query: 398 SGNSIFGSKPAPGTLGTG 415
            G + FGS     ++G G
Sbjct: 947 VGVAPFGSAALSFSIGAG 964



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 66/196 (33%), Positives = 87/196 (44%), Gaps = 37/196 (18%)

Query: 5   SFGTP------FGGGTG---GFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNS 55
           +FG P      FGG T    G  T+S FG  T   T S G+  +S FGS+  +   FG S
Sbjct: 781 AFGAPASSQPAFGGSTAVFFGAATSSGFGATTQ--TASSGS-SSSVFGSTTPSPFTFGGS 837

Query: 56  QTKPG-GLFGTSSFSQPATSTSTG---FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQ 111
               G G FG +  + P +ST+TG   FG G S  TA +       G +   +      Q
Sbjct: 838 AAPAGSGSFGIN-VATPGSSTTTGAFSFGAGQSGSTATSTPFAGGLGQNALGTT----GQ 892

Query: 112 NKPTGFGNFGTSTSSGGLFGTTNT------TSNPFGSTSGS--LFGPSSFTA------AP 157
           + P  F N  ++T S  +FG T T      T  P   TSGS   FG SS  A      AP
Sbjct: 893 STPFAF-NVSSTTESKPVFGGTATPTFGLNTPAPGVGTSGSSLSFGASSAPAQGFVGVAP 951

Query: 158 TGT-TIKFNPPTGTDT 172
            G+  + F+   G+ T
Sbjct: 952 FGSAALSFSIGAGSKT 967


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 117/478 (24%), Positives = 185/478 (38%), Gaps = 80/478 (16%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
            T+S   + +    +  G+  T+AF  S  T GL  +S T       T +   PA++T++G
Sbjct: 986  TSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG 1045

Query: 79   -----FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNK-PTGFGNFGTSTSSGGLF-- 130
                     +S+G+ +T     ST    F  ++  F  N   T    F  ST+S G+   
Sbjct: 1046 PSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEA 1105

Query: 131  --------GTTNTTSNPFGSTSGSLFGPS-SFTAAPTGTTIKFNPPTGTDTMVKAGVSTN 181
                    G+  TT +P  STS  L G S +F   P  T    +PP+     V+   + +
Sbjct: 1106 STRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYH 1165

Query: 182  ISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLF 241
             S      T      + S                    G    + +F SSP  S  T   
Sbjct: 1166 RSPGSTPTTHFPASSTTS--------------------GHSEKSTIFHSSPDASGTTPSS 1205

Query: 242  SSSTTNSGFAYGQNKTAFG----TSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQN 297
            + STT+       ++ + G    T+  G  T PG      ++ +T+ +S P    TT   
Sbjct: 1206 AHSTTSGRGESTTSRISPGSTEITTLPGSTTTPG-----LSEASTTFYSSPRSPTTTLSP 1260

Query: 298  TGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGF 357
               +   +  +G+ ST        T  SQPG    T +  ST     T  GL  ++ T +
Sbjct: 1261 ASMT---SLGVGEEST--------TSRSQPGSTHSTVSPAST-----TTPGLSEESTTVY 1304

Query: 358  ----GAVGSTLFGNNKLTTFGSS--TTSAPSFGTTSGGLFGFGTNTSG----NSIFGSKP 407
                G+  +T+F ++  T+      TT      +T   LF   + TSG    ++ F   P
Sbjct: 1305 SSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSP 1364

Query: 408  APGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAP 465
            A  +  TGL A   TA    +++ F    P   G  GT    +P  +TT+  +G   P
Sbjct: 1365 A--STQTGLPATLTTADLGEESTTF----PSSSGSTGTKL--SPARSTTSGLVGESTP 1414



 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 116/478 (24%), Positives = 184/478 (38%), Gaps = 80/478 (16%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
            T+S   + +    +  G+  T+AF  S  T GL  +S T       T +   PA++T++G
Sbjct: 2543 TSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG 2602

Query: 79   FGFGTST-----GTANTLFGTASTGTSLFSSQNNAFAQNK-PTGFGNFGTSTSSGGLF-- 130
                ++T     G+ +T     ST    F  ++  F  +   T    F  ST+S G+   
Sbjct: 2603 PSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEA 2662

Query: 131  --------GTTNTTSNPFGSTSGSLFGPS-SFTAAPTGTTIKFNPPTGTDTMVKAGVSTN 181
                    G+  TT +P  STS  L G S +F   P  T    +PP+     V+   + +
Sbjct: 2663 STRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYH 2722

Query: 182  ISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLF 241
             S      T      + S                    G    + +F SSP  S  T   
Sbjct: 2723 RSPGSTPTTHFPASSTTS--------------------GHSEKSTIFHSSPDASGTTPSS 2762

Query: 242  SSSTTNSGFAYGQNKTAFG----TSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQN 297
            + STT+       ++ + G    T+  G  T PG      ++ +T+ +S P    TT   
Sbjct: 2763 AHSTTSGRGESTTSRISPGSTEITTLPGSTTTPG-----LSEASTTFYSSPRSPTTTLSP 2817

Query: 298  TGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGF 357
               +   +  +G+ ST        T  SQPG    T +  ST     T  GL  ++ T +
Sbjct: 2818 ASMT---SLGVGEEST--------TSRSQPGSTHSTVSPAST-----TTPGLSEESTTVY 2861

Query: 358  ----GAVGSTLFGNNKLTTFGSS--TTSAPSFGTTSGGLFGFGTNTSG----NSIFGSKP 407
                G+  +T+F  +  T+      TT      +T   LF   + TSG    ++ F   P
Sbjct: 2862 SSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSP 2921

Query: 408  APGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAP 465
            A  +  TGL A   TA    +++ F    P   G  GT    +P  +TT+  +G   P
Sbjct: 2922 A--STQTGLPATLTTADLGEESTTF----PSSSGSTGTTL--SPARSTTSGLVGESTP 2971



 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 151/634 (23%), Positives = 227/634 (35%), Gaps = 113/634 (17%)

Query: 19   TTSTFGQNTGFGT--TSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTS 76
            +++T G++    T  +S GA GT+ F + + T  L G   T P     T + + P ++T+
Sbjct: 1625 SSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTT 1684

Query: 77   TGFG-----FGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKP-----TGFGNFGT---- 122
             G       F +S  + +T    AST TS   S+ +  + ++P     T F    T    
Sbjct: 1685 AGLSEKSTTFYSSPRSPDTTLSPAST-TSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGV 1743

Query: 123  ---STSSGGLFGTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGT------- 170
               ST+S    G+T+TT +P GST+ S  GP S  F ++P  T     P   T       
Sbjct: 1744 SQESTASHSSPGSTDTTLSP-GSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEA 1802

Query: 171  ------------DTMVKAGVST--NISTKHQCITAMKE------YESKSLEELRLEDYQA 210
                         T+  AG +T    ST  Q   + K+        + +  EL    + +
Sbjct: 1803 STPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGS 1862

Query: 211  NRKGPQNQVGAGTTT----------------GLFGSSPATSSATGLFSSST-------TN 247
                P     A +TT                     SPA S+ +GL   ST       + 
Sbjct: 1863 PSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGST 1922

Query: 248  SGFAYGQNKTAFG---------TSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATT---T 295
                + ++ TA G         +STT   ++P        ++ TS  S P   ATT    
Sbjct: 1923 QTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPD 1982

Query: 296  QNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNT 355
             +T       ST    S +  G   +   S    L G +T +   +     T L G T T
Sbjct: 1983 SSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT 2042

Query: 356  GFGAVGSTLFGNN-----------KLTTFG---SSTTSAPSFGTTSGGLFGFGTNTSGNS 401
               +  ST F ++             T+ G    STTS    G+T    F   T T G S
Sbjct: 2043 PGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLS 2102

Query: 402  IFG--SKPAPGTLGTGLGAGFGTALGAGQASLFGNNQP-KIGGPLGTGAFGAPGFNTTTA 458
                 S  +PG+  T L     T  G  Q S   ++ P      L  G+  A  F   + 
Sbjct: 2103 RHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQEST 2162

Query: 459  TLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKP 518
            T           L   + +++        ++S T SP       R  +S        L+ 
Sbjct: 2163 TFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSP-------RTTLSPASSTSPGLQG 2215

Query: 519  TNPAAQKALTTPTHYKLTPR-PATRVRPKALQTT 551
             + A Q   T P     TP  P+T   P    TT
Sbjct: 2216 ESTAFQ---THPASTHTTPSPPSTATAPVEESTT 2246



 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 143/602 (23%), Positives = 222/602 (36%), Gaps = 108/602 (17%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
            T+S   + +    +  G+  T+AF  S  T GL  +S T       T +   PA++T++G
Sbjct: 2069 TSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG 2128

Query: 79   FGFGTST-----GTANTLFGTASTGTSLFSSQNNAFAQNK-PTGFGNFGTSTSSGGLF-- 130
                ++T     G+ +T     ST    F  ++  F  +   T    F  ST+S G+   
Sbjct: 2129 PSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEA 2188

Query: 131  --------GTTNTTSNPFGSTSGSLFGPS-SFTAAPTGTTIKFNPPTGTDTMVKAGVSTN 181
                    G+  TT +P  STS  L G S +F   P  T    +PP+     V+   + +
Sbjct: 2189 STRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYH 2248

Query: 182  ISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLF 241
             S      T      + S                    G    + +F SSP  S  T   
Sbjct: 2249 RSPGSTPTTHFPASSTTS--------------------GHSEKSTIFHSSPDASGTTPSS 2288

Query: 242  SSSTTNSGFAYGQNKTAFG----TSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQN 297
            + STT+       ++ + G    T+  G  T PG      ++ +T+ +S P    TT   
Sbjct: 2289 AHSTTSGRGESTTSRISPGSTEITTLPGSTTTPG-----LSEASTTFYSSPRSPTTTLSP 2343

Query: 298  TGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGF 357
               +   +  +G+ ST        T  SQPG    T +  ST     T  GL  ++ T +
Sbjct: 2344 ASMT---SLGVGEEST--------TSRSQPGSTHSTVSPAST-----TTPGLSEESTTVY 2387

Query: 358  ----GAVGSTLFGNNKLTTFGSS--TTSAPSFGTTSGGLFGFGTNTSG----NSIFGSKP 407
                G+  +T+F     T+      TT      +T   LF   + TSG    ++ F   P
Sbjct: 2388 SSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSP 2447

Query: 408  A------PGTLGTG-LG----------AGFGTALGAGQAS---LFGNNQPKIGGPLGTGA 447
            A      P TL T  LG             GT L   +++   L G + P    P  T  
Sbjct: 2448 ASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTET 2507

Query: 448  FGAPGFNTT-----TATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLF 502
               PG  TT      +T  + +P++P A   P A+     V ++  +S ++S  G +   
Sbjct: 2508 TTLPGSPTTPSLSEKSTTFYTSPRSPDATLSP-ATTTSSGVSEE--SSTSHSQPGSTHTT 2564

Query: 503  RNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGL 562
              P S       R   T+ ++  +  T     L P   T   P    TT    SH   G 
Sbjct: 2565 AFPDSTTTPGLSRHSTTSHSSPGSTDT----TLLPASTTTSGPSQESTT----SHSSPGS 2616

Query: 563  DD 564
             D
Sbjct: 2617 TD 2618



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 153/625 (24%), Positives = 236/625 (37%), Gaps = 111/625 (17%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
            TTS F + +     S  +  T+ F +S+ T G    S T       T++   PA ST++G
Sbjct: 1848 TTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSG 1907

Query: 79   F-----GFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTT 133
                   + +S G+  T+    S+  S  S ++               TS SS     TT
Sbjct: 1908 LVEESTAYHSSPGSTQTMHFPESSTASGRSEESR--------------TSHSS-----TT 1948

Query: 134  NTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC----- 188
            +T S+P  +TS  +  P+S+ ++P  T     P    D+   +G S   +  H       
Sbjct: 1949 HTISSPPSTTSALVEEPTSYHSSPGSTATTHFP----DSSTTSGRSEESTASHSSQDATG 2004

Query: 189  --ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGL------FGSSPATSSATGL 240
              +   +   S  L E       +         G+ TT GL      F SSP  S AT L
Sbjct: 2005 TIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPR-SPATTL 2063

Query: 241  FSSSTTNSGFAY----------GQNKTAFGTSTTGFGTNPGGLFGQQNQQTT-------- 282
              +STT+SG +             + TAF  STT  G +        +  +T        
Sbjct: 2064 SPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAS 2123

Query: 283  SLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFG---VTQASQPGG----LFGTAT 335
            +  S P  ++TT+ +   S G+T T   P + T   FG    T  S PG     LF  +T
Sbjct: 2124 TTTSGPSQESTTSHS---SPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDST 2180

Query: 336  NT------STGTAFGTG---TGLFGQTNTGFGAVG-STLFGNNKLTTFGS----STTSAP 381
             +      ST     TG   T L   ++T  G  G ST F  +  +T  +    ST +AP
Sbjct: 2181 TSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAP 2240

Query: 382  ---------SFGTTSGGLFGFGTNTSGNS----IFGSKPAPGTLGTGLGAGFGTALGAGQ 428
                     S G+T    F   + TSG+S    IF S  +P   GT   +   T  G G+
Sbjct: 2241 VEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHS--SPDASGTTPSSAHSTTSGRGE 2298

Query: 429  ASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHI 488
            ++    +          G+   PG +  + T  + +P++P     P AS     V ++  
Sbjct: 2299 STTSRISPGSTEITTLPGSTTTPGLSEASTTF-YSSPRSPTTTLSP-ASMTSLGVGEEST 2356

Query: 489  NSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPATR------ 542
             S +      S +     + P   EE    T  ++    T  T +  TP  + R      
Sbjct: 2357 TSRSQPGSTHSTVSPASTTTPGLSEE--STTVYSSSPGSTETTVFPRTPTTSVRGEEPTT 2414

Query: 543  --VRPKALQTTGTAKSHLFDGLDDD 565
               RP +  TT   +     GL ++
Sbjct: 2415 FHSRPASTHTTLFTEDSTTSGLTEE 2439



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 138/567 (24%), Positives = 211/567 (37%), Gaps = 117/567 (20%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
            TT+  G+ +    +S G+ GT+   + + T GL G S         T + + P + T+  
Sbjct: 2933 TTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPS 2992

Query: 79   FG-----FGTSTGTANTLFGTASTGTSLFSSQNN-AFAQNKPTGFGNFGTSTSSGGLF-- 130
                   F TS  + +     A+T +S  S +++ + +Q   T    F  ST++ GL   
Sbjct: 2993 LSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQE 3052

Query: 131  --------GTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNP-PTGTDTMVKAGVS 179
                    G+T  T +P GST+ S  G  S  F ++P  T     P  T T  +V+A   
Sbjct: 3053 PTASHSSQGSTEATLSP-GSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTP 3111

Query: 180  TNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATG 239
            T+ ST                                   G+  TT     +PA+S++ G
Sbjct: 3112 THSST-----------------------------------GSLHTT----LTPASSTSAG 3132

Query: 240  LFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTG 299
            L   STT   +    + T           +P G      + +T+  S+P    ++T  T 
Sbjct: 3133 LQEESTTFQSWPSSSDTT----------PSPPGTTAAPVEVSTTYHSRP----SSTPTTH 3178

Query: 300  FSFGNTSTIGQPSTNTMGLFGVTQASQPG----GLFGTATNTSTGTAFGTGTGLFGQTNT 355
            FS  +T T+G+   +T      T  S PG     LF T + TS      T + +   +  
Sbjct: 3179 FSASST-TLGRSEEST------TVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTE 3231

Query: 356  GFGAVGSTLFG--NNKLTTFGSS-----TTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPA 408
                 GST     + K TTF SS     TT +P+  TTS G+    T         S   
Sbjct: 3232 TTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPA-STTSSGVSEESTT--------SHSR 3282

Query: 409  PGTLGTGLGAGFGTALGAGQASLFGNNQP-KIGGPLGTGAFGAPGFNTTTATLGFGAPQA 467
            PG+  T    G  T  G  Q S   ++ P      L  G+  A      + T   G    
Sbjct: 3283 PGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGST 3342

Query: 468  PVALTDPNASAAQQAVLQQHINSLTYSPF------------GDSPLFRNPMSDPKKKEER 515
               L   N +A+        ++S T SP             G+S  F+   S P  K+  
Sbjct: 3343 ETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQ---SWPNSKDTT 3399

Query: 516  -LKPTNPAAQKALTTPTHYKLTPRPAT 541
               PT  +A   L+T +H   +  P T
Sbjct: 3400 PAPPTTTSAFVELSTTSHGSPSSTPTT 3426



 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 133/557 (23%), Positives = 207/557 (37%), Gaps = 97/557 (17%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
            TT+  G+ +    +S G+ GT    + + T GL G S         T + + P + T+  
Sbjct: 4016 TTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPS 4075

Query: 79   FG-----FGTSTGTANTLFGTASTGTSLFSSQNN-AFAQNKPTGFGNFGTSTSSGGLFGT 132
                   F TS  + +     A+T +S  S +++ + +Q   T    F  ST++ GL   
Sbjct: 4076 LSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQE 4135

Query: 133  TNTTSNPFGSTSGSLFGPSSFTAAPTG---TTIKFNPPTGTDTMVKAGVSTNISTKHQCI 189
              T+ +  GST  +L  P S TA+  G   TT   +P     T++     T+   +    
Sbjct: 4136 PTTSHSSQGSTEATL-SPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTP 4194

Query: 190  TAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSG 249
            T                          +  G+  TT     +PA+S++TGL   STT   
Sbjct: 4195 T-------------------------HSSTGSLHTT----LTPASSTSTGLQEESTTFQS 4225

Query: 250  FAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIG 309
            +    + T    STT              + +T+  S+P    ++T  T FS  +T T+G
Sbjct: 4226 WPSSSDTTPSPPSTTAVPV----------EVSTTYHSRP----SSTPTTHFSASST-TLG 4270

Query: 310  QPSTNTMGLFGVTQASQPG----GLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLF 365
            +   +T      T  S PG     LF T + TS      T + +   +       GST  
Sbjct: 4271 RSEEST------TVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTT 4324

Query: 366  G--NNKLTTFGSS-----TTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGA 418
               + K TTF SS     TT +P+  TTS G+    T         S   PG++ T    
Sbjct: 4325 AGLSEKSTTFYSSPRSPDTTLSPA-STTSSGVSEESTT--------SHSRPGSMHTTAFP 4375

Query: 419  GFGTALGAGQASLFGNNQP-KIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNAS 477
               T  G  Q S   ++ P      L  G+  A      + T           L   N +
Sbjct: 4376 SSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTT 4435

Query: 478  AAQQAVLQQHINSLTYSPF------------GDSPLFRNPMSDPKKKEER-LKPTNPAAQ 524
            A+        ++S T SP             G+S  F+   S P  K+     PT  +A 
Sbjct: 4436 ASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQ---SWPNSKDTTPAPPTTTSAF 4492

Query: 525  KALTTPTHYKLTPRPAT 541
              L+T +H   +  P T
Sbjct: 4493 VELSTTSHGSPSSTPTT 4509



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 138/586 (23%), Positives = 218/586 (37%), Gaps = 61/586 (10%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
            TTS F + +     S  +  T+   + + T GL   S T       T +   P + T++G
Sbjct: 793  TTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSG 852

Query: 79   FGFGTST---GTANTLFGTAST-------GTSLFSSQNNAFAQNKP---TGFGNFGTSTS 125
             G  ++T    T +T+    ST        TS  SS  +    + P   T  G    ST+
Sbjct: 853  RGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTA 912

Query: 126  SGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTK 185
            S      T T   P  ST+  L G S+ +   +G+      P  T T    G+S   +T 
Sbjct: 913  SHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT---PGLSERSTTF 969

Query: 186  HQC----ITAMKEYESKSLEELRLEDYQANRKGPQNQVG---AGTTTGLFGSSPATSSAT 238
            H       T +    + S           +R G  +      + TT GL   S  + S+ 
Sbjct: 970  HSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSP 1029

Query: 239  G-----LFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQAT 293
            G     L  +STT SG +     +   + +T    +PG         TT+L    FGQ +
Sbjct: 1030 GSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPG--------STTAL---SFGQES 1078

Query: 294  TTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQT 353
            TT ++  + G+T T   P + T    G+ +AS        +  T+   A  T  GL G++
Sbjct: 1079 TTFHS--NPGSTHTTLFPDSTTSS--GIVEASTRVHSSTGSPRTTLSPASSTSPGLQGES 1134

Query: 354  NTGFGAVGSTLFGNNKLTT----FGSSTTSAPSFGTTSGGLFGFGTNTSGNS----IFGS 405
                    ST    +  +T       STT   S G+T    F   + TSG+S    IF S
Sbjct: 1135 TAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHS 1194

Query: 406  KPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAP 465
              +P   GT   +   T  G G+++    +          G+   PG +  + T  + +P
Sbjct: 1195 --SPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF-YSSP 1251

Query: 466  QAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQK 525
            ++P     P AS     V ++   S +      S +     + P   EE     + +   
Sbjct: 1252 RSPTTTLSP-ASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGS 1310

Query: 526  ALTTPTHYKLT-----PRPAT-RVRPKALQTTGTAKSHLFDGLDDD 565
              TT   +  T       P T   RP +  TT   +     GL ++
Sbjct: 1311 TETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEE 1356



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 149/620 (24%), Positives = 231/620 (37%), Gaps = 101/620 (16%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
            TTS F + +     S  +  T+ F +S+ T G    S T       T++   PA ST++G
Sbjct: 3405 TTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSG 3464

Query: 79   F-----GFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTT 133
                   + +S G+  T+    S  TS               G G   T++ S     TT
Sbjct: 3465 LVEESTTYHSSPGSTQTMHFPESDTTS---------------GRGEESTTSHSS----TT 3505

Query: 134  NTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQC----- 188
            +T S+   +TS  +  P+S+ ++P  T     P    D+   +G S   +  H       
Sbjct: 3506 HTISSAPSTTSALVEEPTSYHSSPGSTATTHFP----DSSTTSGRSEESTASHSSQDATG 3561

Query: 189  --ITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGL------FGSSPATSSATGL 240
              +   +   S  L E       +         G+ TT GL      F SSP  S AT L
Sbjct: 3562 TIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPR-SPATTL 3620

Query: 241  FSSSTTNSGFAY----------GQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKP-- 288
              +STT+SG +             + TAF  STT  G +        +  +T     P  
Sbjct: 3621 SPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAS 3680

Query: 289  ---FGQATTTQNTGFSFGNTSTIGQPSTNTMGLFG---VTQASQPGG----LFGTATNT- 337
                G +  +  +  S G+T T   P + T   FG    T  S PG     LF  +T + 
Sbjct: 3681 TTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSS 3740

Query: 338  -----STGTAFGTG---TGLFGQTNTGFGAVG-STLFGNNKLTTFGS----STTSAP--- 381
                 ST     TG   T L   ++T  G  G ST F  +  +T  +    ST +AP   
Sbjct: 3741 GIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEE 3800

Query: 382  ------SFGTTSGGLFGFGTNTSGNS----IFGSKPAPGTLGTGLGAGFGTALGAGQASL 431
                  S G+T    F   + TSG+S    IF S  +P   GT   +   T  G G+++ 
Sbjct: 3801 STTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHS--SPDASGTTPSSAHSTTSGRGESTT 3858

Query: 432  FGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSL 491
               +          G+   PG +  + T  + +P++P     P AS     V ++   S 
Sbjct: 3859 SRISPGSTEITTLPGSTTTPGLSEASTTF-YSSPRSPTTTLSP-ASMTSLGVGEESTTSR 3916

Query: 492  TYSPFGDSPLFRNPMSDPKKKEE--RLKPTNPAAQKALTTPTHYKLTPR---PAT-RVRP 545
            +      S +     + P   EE   +  ++P + +    P     + R   P T   RP
Sbjct: 3917 SQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRP 3976

Query: 546  KALQTTGTAKSHLFDGLDDD 565
             +  TT   +     GL ++
Sbjct: 3977 ASTHTTLFTEDSTTSGLTEE 3996



 Score = 65.1 bits (157), Expect = 6e-10
 Identities = 129/553 (23%), Positives = 205/553 (37%), Gaps = 89/553 (16%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
            TT+  G+ +    +S G+ GT    + + T GL G S          S  S  +T T+T 
Sbjct: 1376 TTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGEST--------PSRLSPSSTETTTL 1427

Query: 79   FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138
             G  T+          +   T+ ++S  +  A   P        +T+S G+   ++T+ +
Sbjct: 1428 PGSPTTP-------SLSEKSTTFYTSPRSPDATLSP-------ATTTSSGVSEESSTSHS 1473

Query: 139  PFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESK 198
              GST  + F  S+ T+  +      +   G+     +  ST  S+  Q  T        
Sbjct: 1474 QPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGD 1533

Query: 199  SLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATG-----LFSSSTTNSGFAYG 253
            +   L  +D                T+GL  +S  T S+TG     L  +S+T++G    
Sbjct: 1534 TETTLLPDD--------------TITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEE 1579

Query: 254  QNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPST 313
                    S++    +P G      + +T+  S+P    ++T  T FS  +T T+G+   
Sbjct: 1580 STTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRP----SSTPTTHFSASST-TLGRSEE 1634

Query: 314  NTMGLFGVTQASQPG----GLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFG--N 367
            +T      T  S PG     LF T + TS      T + +   +       GST     +
Sbjct: 1635 ST------TVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLS 1688

Query: 368  NKLTTFGSS-----TTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGT 422
             K TTF SS     TT +P+  TTS G+    T         S   PG+  T    G  T
Sbjct: 1689 EKSTTFYSSPRSPDTTLSPA-STTSSGVSEESTT--------SHSRPGSTHTTAFPGSTT 1739

Query: 423  ALGAGQASLFGNNQP-KIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQ 481
              G  Q S   ++ P      L  G+  A      + T           L   N +A+  
Sbjct: 1740 MPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGL 1799

Query: 482  AVLQQHINSLTYSPF------------GDSPLFRNPMSDPKKKEER-LKPTNPAAQKALT 528
                  ++S T SP             G+S  F+   S P  K+     PT  +A   L+
Sbjct: 1800 LEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQ---SWPSSKDTMPAPPTTTSAFVELS 1856

Query: 529  TPTHYKLTPRPAT 541
            T +H   +  P T
Sbjct: 1857 TTSHGSPSSTPTT 1869



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 174/771 (22%), Positives = 272/771 (35%), Gaps = 128/771 (16%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
            T+S   + +    +  G+  T+AF  S  T GL     T       T +   P ++T++ 
Sbjct: 4100 TSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASS 4159

Query: 79   FG-----FGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTT 133
             G     F +S G   T      T TS                 G    ST +    G+ 
Sbjct: 4160 LGQQSTTFHSSPGDTETTLLPDDTITS-----------------GLVEASTPTHSSTGSL 4202

Query: 134  NTTSNPFGSTSGSLFGPS-SFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192
            +TT  P  STS  L   S +F + P+ +    +PP  + T V   VST   ++    T  
Sbjct: 4203 HTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPP--STTAVPVEVSTTYHSRPSS-TPT 4259

Query: 193  KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAY 252
              + + S    R E+       P       T T LF +  ATS   G  ++S  +SG   
Sbjct: 4260 THFSASSTTLGRSEESTTVHSSP-----GATGTALFPTRSATSVLVGEPTTSPISSG--- 4311

Query: 253  GQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATT-----TQNTGFSF----- 302
                TA   STT  G          ++++T+ +S P    TT     T ++G S      
Sbjct: 4312 STETTALPGSTTTAGL---------SEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTS 4362

Query: 303  ----GNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFG 358
                G+  T   PS+ TM   GV+Q S        +T+T+      T + L  ++ T   
Sbjct: 4363 HSRPGSMHTTAFPSSTTMP--GVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS 4420

Query: 359  AVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGT---NTSGNSIFGSKPAPGTLGTG 415
            + GST             TT  P   TT+ GL    T   +++G+      PA  T   G
Sbjct: 4421 SPGST------------ETTLLPD-NTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQG 4467

Query: 416  LGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPG------FNTTTATLGFG-----A 464
                F +   +   +            L T + G+P       F+ ++ TLG        
Sbjct: 4468 ESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTV 4527

Query: 465  PQAPVA-LTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTN--- 520
              +PVA  T P+ + +  + L +   +   SP G +     P S+          T+   
Sbjct: 4528 HSSPVATATTPSPARSTTSGLVEESTTYHSSP-GSTQTMHFPESNTTSGRGEESTTSHSS 4586

Query: 521  --------PAAQKALT-TPTHYKLTP-RPATRVRPKALQTTGTAKSHLFDGLDDDEPSLA 570
                    P+   AL   PT Y  +P   AT   P +  T+G ++         D    A
Sbjct: 4587 TTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQD----A 4642

Query: 571  NGAF-MPKKSIKKLVLKNLNNSNLFS--------PVNRDSENL--------ASPSEYPEN 613
             G   +P +S   ++L     S + S        P +  +  L        +SPS  P  
Sbjct: 4643 TGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTT 4702

Query: 614  GERFSFLSKPVDENHQQDGDEDSLVSHFYT-NPIAKPIPQTPESAGNKHSNSNSVDDTIV 672
               FS  S  +  + +      S V+   T +P         E +   HS+  S      
Sbjct: 4703 --HFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHF 4760

Query: 673  ALNMRAALRNGLEGSSEETSFHDESLQDDREEI---ENNSYHMHPAGIILT 720
              +  A+ R+    +S  ++ H  S           E  SYH  P  I  T
Sbjct: 4761 PESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATT 4811



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 169/757 (22%), Positives = 269/757 (35%), Gaps = 113/757 (14%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
           T S   + +    +  GA GT+ F S + T    G  +T P       + + P ++T+ G
Sbjct: 216 TNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAG 275

Query: 79  FG------FGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPT---GFGNFGT------- 122
                   + +      TL    +T + +      + ++  PT    F +  T       
Sbjct: 276 LSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQE 335

Query: 123 STSSGGLFGTTNTTSNPFGSTSGSLFGPSS--FTAAPTGT-TIKFNPPTGTDTMVKAGVS 179
           ST+S  + G+T+TT +P G+T+ S  GP S  F ++P  T T +    T T  +++A   
Sbjct: 336 STASHSIPGSTDTTLSP-GTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTP 394

Query: 180 TNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATG 239
            + ST     T      S +  E     +Q+    P ++           +SPA S  T 
Sbjct: 395 VHSSTGSPHTTLSP--SSSTTHEGEPTTFQS---WPSSK----------DTSPAPSGTTS 439

Query: 240 LF-SSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATT---- 294
            F   STT          T F  S+T  G          ++++T + S P   ATT    
Sbjct: 440 AFVKLSTTYHSSPSSTPTTHFSASSTTLG---------HSEESTPVHSSPVATATTPPPA 490

Query: 295 --------TQNTGF--SFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFG 344
                    ++T +  S G+T T+  P ++T        A+  G    T ++T + TA  
Sbjct: 491 RSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAAL 550

Query: 345 TGTGL---FGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNS 401
             T      G T T      ST+ G ++ +    S+  A +      G      +T    
Sbjct: 551 AHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAG------STPSVL 604

Query: 402 IFGSKPAP---GTLGTGLGAGFGTALGAGQASLFGNNQPKIGG----PLGTGAFGAPGFN 454
           +  S P+P   G++ T    G  T  G  + S    + P+       P    + G    +
Sbjct: 605 VGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEES 664

Query: 455 TT-------TATLGF-GAPQAPVALTDPNASAAQQAVLQQHIN--SLTYSPFGDSPLFRN 504
           TT       T T  F G+   P    +  AS +        ++  S T S  G  P +  
Sbjct: 665 TTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLG--PEYTT 722

Query: 505 PMSDPKKKEERLKPTNPAAQKAL--TTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGL 562
             S P   E  L P N  A   L  + P H   T  P T + P A  TT   +S  F   
Sbjct: 723 FHSRPGSTETTLLPDNTTASGLLEASMPVH-SSTRSPHTTLSP-AGSTTRQGESTTFHSW 780

Query: 563 DDDEPSLANGAFMPKKSIKKLVLKNLNNSNLFSPVNRDSENLASPSEYPENGERFSFLSK 622
               PS  +    P  +    V  +  +    S +         P+ +       S L +
Sbjct: 781 ----PSSKDTRPAPPTTTSAFVEPSTTSHGSPSSI---------PTTHISARSTTSGLVE 827

Query: 623 PVDENHQQDGDEDSLVSHFYTNPIAKPIPQTPESAGNKHSNS----NSVDDTIVALNMRA 678
                H   G   ++  HF   P +       E +   HS++    +S   T  AL    
Sbjct: 828 ESTTYHSSPGSTQTM--HF---PESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEP 882

Query: 679 ALRNGLEGSSEETSFHDESLQDDREEIENNSYHMHPA 715
              +   GS+  T F D S    R E    S+    A
Sbjct: 883 TSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDA 919



 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 94/391 (24%), Positives = 148/391 (37%), Gaps = 61/391 (15%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
            TTS     +     S G+  T+A   S  T GL   S T       T +    A+ST+ G
Sbjct: 4653 TTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLG 4712

Query: 79   FGFGTST------GTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLF-- 130
                ++T       TA T     ST + L        +    T   +F  S+++ G    
Sbjct: 4713 RSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEE 4772

Query: 131  ------GTTNTTSNPFGSTSGSLFGPSSFTAAPTG-TTIKFNPPTGTDTMVKAGVSTNIS 183
                   TT+T S+P  +TS  +  P+S+ ++P    T  F   + T    +   +++ S
Sbjct: 4773 SRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSS 4832

Query: 184  TKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGA-GTTTGLFGS------------ 230
                 IT +  + + S        +  +    +  + +  TT GL               
Sbjct: 4833 PDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPD 4892

Query: 231  ---SPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSK 287
               SPA+ +++ +    T+    A   + TAF  STT  G          +Q++T+  SK
Sbjct: 4893 QTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGL---------SQESTTFHSK 4943

Query: 288  PFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGT 347
            P G   TT + G     TS+  Q  T        T  SQPG    T +  ST     T  
Sbjct: 4944 P-GSTETTLSPGSI--TTSSFAQEFT--------TPHSQPGSALSTVSPAST-----TVP 4987

Query: 348  GLFGQTNTGFGAVGSTLFGNNKLTTFGSSTT 378
            GL  ++ T + + GST     + T F  S T
Sbjct: 4988 GLSEESTTFYSSPGST-----ETTAFSHSNT 5013



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 142/606 (23%), Positives = 227/606 (37%), Gaps = 76/606 (12%)

Query: 28   GFGTTSGGAFGTSAFGSS--NNTGGLFGNSQTKPG-GLFGTSSFSQPATSTSTGFGFGTS 84
            G  TT G +  ++ F SS  + T  L   S T  G G   T+S SQP ++ ST     T+
Sbjct: 2316 GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTT 2375

Query: 85   TG----TANTLFGTA--STGTSLFS-SQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTS 137
            T      + T++ ++  ST T++F  +   +    +PT F +   ST +  LF   +TTS
Sbjct: 2376 TPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTT-LFTEDSTTS 2434

Query: 138  NPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192
               G T  S   P S  +  TG     TT      + T         T +S      + +
Sbjct: 2435 ---GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGL 2491

Query: 193  KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGS--------SPATSSATGLFSSS 244
                + S       +       P     +  +T  + S        SPAT++++G+   S
Sbjct: 2492 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 2551

Query: 245  TTNSGFAYGQNKTAFGTSTTGFG---------TNPGG----------LFGQQNQQTTSLF 285
            +T+       + TAF  STT  G         ++PG                +Q++T+  
Sbjct: 2552 STSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSH 2611

Query: 286  SKPFGQATTT---QNTGFSFGNTSTI--GQPSTNTMGLF-------GVTQASQPGGLFGT 333
            S P    T       T  SFG  ST     P +    LF       G+ +AS        
Sbjct: 2612 SSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTG 2671

Query: 334  ATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTT----FGSSTTSAPSFGTTSGG 389
            +  T+   A  T  GL G++ T      ST    +  +T       STT   S G+T   
Sbjct: 2672 SPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTT 2731

Query: 390  LFGFGTNTSGNS----IFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGT 445
             F   + TSG+S    IF S  +P   GT   +   T  G G+++    +          
Sbjct: 2732 HFPASSTTSGHSEKSTIFHS--SPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLP 2789

Query: 446  GAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNP 505
            G+   PG +  + T  + +P++P     P AS     V ++   S +      S +    
Sbjct: 2790 GSTTTPGLSEASTTF-YSSPRSPTTTLSP-ASMTSLGVGEESTTSRSQPGSTHSTVSPAS 2847

Query: 506  MSDPKKKEE--RLKPTNPAAQKALTTPTHYKLTPR---PAT-RVRPKALQTTGTAKSHLF 559
             + P   EE   +  ++P + +    P     + R   P T   RP +  TT   +    
Sbjct: 2848 TTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTT 2907

Query: 560  DGLDDD 565
             GL ++
Sbjct: 2908 SGLTEE 2913



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 154/627 (24%), Positives = 234/627 (37%), Gaps = 122/627 (19%)

Query: 28   GFGTTSGGAFGTSAFGSS--NNTGGLFGNSQTKPG-GLFGTSSFSQPATSTSTGFGFGTS 84
            G  TT G +  ++ F SS  + T  L   S T  G G   T+S SQP ++ ST     T+
Sbjct: 3873 GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTT 3932

Query: 85   TG----TANTLFGTA--STGTSLFS-SQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTS 137
            T      + T++ ++  ST T++F  S   +  + +PT F +   ST +  LF   +TTS
Sbjct: 3933 TPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTT-LFTEDSTTS 3991

Query: 138  NPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192
               G T  S   P S  +  TG     TT      + T         T +S      + +
Sbjct: 3992 ---GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 4048

Query: 193  KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGS--------SPATSSATGLFSSS 244
                + S       +       P     +  +T  + S        SPAT++++G+   S
Sbjct: 4049 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 4108

Query: 245  TTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKP-------FGQATTTQN 297
            +T+       + TAF  STT  G +        +Q +T     P        GQ +TT +
Sbjct: 4109 STSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFH 4168

Query: 298  TGFSFGNTSTIGQPSTNTMGLFGVTQASQP-----GGLFGT---ATNTSTG-----TAF- 343
            +  S G+T T   P        G+ +AS P     G L  T   A++TSTG     T F 
Sbjct: 4169 S--SPGDTETTLLPDDTITS--GLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQ 4224

Query: 344  -------------------------------GTGTGLFGQTNTGFG-------------A 359
                                            T T  F  ++T  G             A
Sbjct: 4225 SWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGA 4284

Query: 360  VGSTLFGNNKLTT--FGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSK--PAPGTLGTG 415
             G+ LF     T+   G  TTS  S G+T        T T+G S   +    +P +  T 
Sbjct: 4285 TGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTT 4344

Query: 416  LGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPN 475
            L     T+ G  + S   +++P   G + T AF       ++ T+   + ++  + + P 
Sbjct: 4345 LSPASTTSSGVSEESTTSHSRP---GSMHTTAF------PSSTTMPGVSQESTASHSSPG 4395

Query: 476  ASAAQQAVLQQHINSLTYSPFG-DSPLFRNPMSDPKKKEERLKPTNPAAQKAL--TTPTH 532
            ++    +       S T S  G +S  F    S P   E  L P N  A   L  +TP H
Sbjct: 4396 STDTTLSP-----GSTTASSLGPESTTFH---SSPGSTETTLLPDNTTASGLLEASTPVH 4447

Query: 533  YKLTPRPATRVRPKALQTTGTAKSHLF 559
               T  P T + P A  TT   +S  F
Sbjct: 4448 -SSTGSPHTTLSP-AGSTTRQGESTTF 4472



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 125/510 (24%), Positives = 192/510 (37%), Gaps = 67/510 (13%)

Query: 28   GFGTTSGGAFGTSAFGSS--NNTGGLFGNSQTKPG-GLFGTSSFSQPATSTSTGFGFGTS 84
            G  TT G +  ++ F SS  + T  L   S T  G G   T+S SQP ++ ST     T+
Sbjct: 2790 GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTT 2849

Query: 85   TG----TANTLFGTA--STGTSLFS-SQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTS 137
            T      + T++ ++  ST T++F  S   +    +PT F +   ST +  LF   +TTS
Sbjct: 2850 TPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTT-LFTEDSTTS 2908

Query: 138  NPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192
               G T  S   P S  +  TG     TT      + T         T +S      + +
Sbjct: 2909 ---GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGL 2965

Query: 193  KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGS--------SPATSSATGLFSSS 244
                + S       +       P     +  +T  + S        SPAT++++G+   S
Sbjct: 2966 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 3025

Query: 245  TTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKP-------FGQATTTQN 297
            +T+       + TAF  STT  G +        +Q +T     P        GQ +TT +
Sbjct: 3026 STSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFH 3085

Query: 298  TGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLF------- 350
            +  S G+T T   P        G+ +AS P      + +T+   A  T  GL        
Sbjct: 3086 S--SPGDTETTLLPDDTITS--GLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQ 3141

Query: 351  ---GQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPS--FGTTSGGLFGFGTNTSGNSIFGS 405
                 ++T     G+T       TT+ S  +S P+  F  +S  L   G +    ++  S
Sbjct: 3142 SWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTL---GRSEESTTVHSS 3198

Query: 406  KPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTT-----ATL 460
               PG  GT L   F T              P   G   T A   PG  TT      +T 
Sbjct: 3199 ---PGATGTAL---FPTRSATSVLVGEPTTSPISSGSTETTAL--PGSTTTAGLSEKSTT 3250

Query: 461  GFGAPQAPVALTDPNASAAQQAVLQQHINS 490
             + +P++P     P AS     V ++   S
Sbjct: 3251 FYSSPRSPDTTLSP-ASTTSSGVSEESTTS 3279



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 124/510 (24%), Positives = 191/510 (37%), Gaps = 67/510 (13%)

Query: 28   GFGTTSGGAFGTSAFGSS--NNTGGLFGNSQTKPG-GLFGTSSFSQPATSTSTGFGFGTS 84
            G  TT G +  ++ F SS  + T  L   S T  G G   T+S SQP ++ ST     T+
Sbjct: 1233 GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTT 1292

Query: 85   TG----TANTLFGTA--STGTSLFS-SQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTS 137
            T      + T++ ++  ST T++F  S   +    +PT F +   ST +  LF   +TTS
Sbjct: 1293 TPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTT-LFTEDSTTS 1351

Query: 138  NPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192
               G T  S   P S  +  TG     TT      + T         T +S      + +
Sbjct: 1352 ---GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 1408

Query: 193  KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGS--------SPATSSATGLFSSS 244
                + S       +       P     +  +T  + S        SPAT++++G+   S
Sbjct: 1409 VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 1468

Query: 245  TTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKP-------FGQATTTQN 297
            +T+       + TAF  STT    +        +Q +T     P        GQ +TT +
Sbjct: 1469 STSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFH 1528

Query: 298  TGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLF------- 350
            +  S G+T T   P        G+ +AS P      + +T+   A  T  GL        
Sbjct: 1529 S--SPGDTETTLLPDDTITS--GLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQ 1584

Query: 351  ---GQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPS--FGTTSGGLFGFGTNTSGNSIFGS 405
                 ++T     G+T       TT+ S  +S P+  F  +S  L   G +    ++  S
Sbjct: 1585 SWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTL---GRSEESTTVHSS 1641

Query: 406  KPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTT-----ATL 460
               PG  GT L   F T              P   G   T A   PG  TT      +T 
Sbjct: 1642 ---PGATGTAL---FPTRSATSVLVGEPTTSPISSGSTETTAL--PGSTTTAGLSEKSTT 1693

Query: 461  GFGAPQAPVALTDPNASAAQQAVLQQHINS 490
             + +P++P     P AS     V ++   S
Sbjct: 1694 FYSSPRSPDTTLSP-ASTTSSGVSEESTTS 1722



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 62/265 (23%), Positives = 100/265 (37%), Gaps = 33/265 (12%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQT---KPGGLFGT--SSFSQPAT 73
            TTS   + +    +S    G +   +   T G    S T    PG +  T  S+ + P  
Sbjct: 4818 TTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGL 4877

Query: 74   STSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTT 133
            S  +   + +S     TL   + T +S+     + ++Q + T    F  ST++ GL   +
Sbjct: 4878 SAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQES 4937

Query: 134  NTTSNPFGSTSGSLFGPSSFTA---APTGTTIKFNPPTGTDTMVKA-----GVSTNISTK 185
             T  +  GST  +L  P S T    A   TT    P +   T+  A     G+S   +T 
Sbjct: 4938 TTFHSKPGSTETTL-SPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTF 4996

Query: 186  HQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSST 245
            +   ++    E+ +          + +  P       T T L    PAT + T +     
Sbjct: 4997 Y---SSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVL----PATLTTTDI----- 5044

Query: 246  TNSGFAYGQNKTAFGTSTTGFGTNP 270
                   GQ  TAF +S+   GT P
Sbjct: 5045 -------GQESTAFHSSSDATGTTP 5062



 Score = 31.6 bits (70), Expect = 7.3
 Identities = 55/223 (24%), Positives = 78/223 (34%), Gaps = 50/223 (22%)

Query: 235 SSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATT 294
           S+AT  F  S+TNSG +     +  G   TG    P       +   TS+F    G+  T
Sbjct: 205 STATKHFLDSSTNSGHSEESTVSHSGPGATGTTLFP-------SHSATSVF---VGEPKT 254

Query: 295 TQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTN 354
           +  T  S   T+  G  +T  +     T  S P      + + +   A  T +G+  ++ 
Sbjct: 255 SPITSASMETTALPGSTTTAGLSEKSTTFYSSP-----RSPDRTLSPARTTSSGVSEKST 309

Query: 355 TGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGT 414
           T     G T         F  STT  P     S         T+ +SI      PG+  T
Sbjct: 310 TSHSRPGPT-----HTIAFPDSTT-MPGVSQES---------TASHSI------PGSTDT 348

Query: 415 GLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTT 457
            L  G  T              P   GP  T    +PG+  TT
Sbjct: 349 TLSPGTTT--------------PSSLGPESTTFHSSPGYTKTT 377



 Score = 31.2 bits (69), Expect = 9.5
 Identities = 55/237 (23%), Positives = 86/237 (36%), Gaps = 24/237 (10%)

Query: 31   TTSG-GAFGTSAFGSSNNTGGLFGNSQTKPGGLFG--TSSFSQPATSTSTGFGFGTSTG- 86
            TT G  A  T  + SS +       +      + G  TS +SQ  ++ +T F   T+T  
Sbjct: 4873 TTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSG 4932

Query: 87   ------TANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGT--------STSSGGLFGT 132
                  T ++  G+  T  S  S   ++FAQ   T     G+        ST+  GL   
Sbjct: 4933 LSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEE 4992

Query: 133  TNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192
            + T  +  GST  + F  S+  +  +  +  F    G    V     T      +     
Sbjct: 4993 STTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFH 5052

Query: 193  KEYESKSLEELRLEDYQANRKGPQNQV---GAGTTTGLFGSSPATSSATGLFSSSTT 246
               ++     L      ++  G         + T T LF   PA+SS +GL   STT
Sbjct: 5053 SSSDATGTTPLPARSTASDLVGEPTTFYISPSPTYTTLF---PASSSTSGLTEESTT 5106


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
           sapiens]
          Length = 2036

 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 117/478 (24%), Positives = 185/478 (38%), Gaps = 80/478 (16%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
           T+S   + +    +  G+  T+AF  S  T GL  +S T       T +   PA++T++G
Sbjct: 473 TSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG 532

Query: 79  -----FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNK-PTGFGNFGTSTSSGGLF-- 130
                    +S+G+ +T     ST    F  ++  F  N   T    F  ST+S G+   
Sbjct: 533 PSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEA 592

Query: 131 --------GTTNTTSNPFGSTSGSLFGPS-SFTAAPTGTTIKFNPPTGTDTMVKAGVSTN 181
                   G+  TT +P  STS  L G S +F   P  T    +PP+     V+   + +
Sbjct: 593 STRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYH 652

Query: 182 ISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLF 241
            S      T      + S                    G    + +F SSP  S  T   
Sbjct: 653 RSPGSTPTTHFPASSTTS--------------------GHSEKSTIFHSSPDASGTTPSS 692

Query: 242 SSSTTNSGFAYGQNKTAFG----TSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQN 297
           + STT+       ++ + G    T+  G  T PG      ++ +T+ +S P    TT   
Sbjct: 693 AHSTTSGRGESTTSRISPGSTEITTLPGSTTTPG-----LSEASTTFYSSPRSPTTTLSP 747

Query: 298 TGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGF 357
              +   +  +G+ ST        T  SQPG    T +  ST     T  GL  ++ T +
Sbjct: 748 ASMT---SLGVGEEST--------TSRSQPGSTHSTVSPAST-----TTPGLSEESTTVY 791

Query: 358 ----GAVGSTLFGNNKLTTFGSS--TTSAPSFGTTSGGLFGFGTNTSG----NSIFGSKP 407
               G+  +T+F ++  T+      TT      +T   LF   + TSG    ++ F   P
Sbjct: 792 SSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSP 851

Query: 408 APGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAP 465
           A  +  TGL A   TA    +++ F    P   G  GT    +P  +TT+  +G   P
Sbjct: 852 A--STQTGLPATLTTADLGEESTTF----PSSSGSTGTKL--SPARSTTSGLVGESTP 901



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 138/586 (23%), Positives = 218/586 (37%), Gaps = 61/586 (10%)

Query: 19  TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
           TTS F + +     S  +  T+   + + T GL   S T       T +   P + T++G
Sbjct: 280 TTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSG 339

Query: 79  FGFGTST---GTANTLFGTAST-------GTSLFSSQNNAFAQNKP---TGFGNFGTSTS 125
            G  ++T    T +T+    ST        TS  SS  +    + P   T  G    ST+
Sbjct: 340 RGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTA 399

Query: 126 SGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTK 185
           S      T T   P  ST+  L G S+ +   +G+      P  T T    G+S   +T 
Sbjct: 400 SHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT---PGLSERSTTF 456

Query: 186 HQC----ITAMKEYESKSLEELRLEDYQANRKGPQNQVG---AGTTTGLFGSSPATSSAT 238
           H       T +    + S           +R G  +      + TT GL   S  + S+ 
Sbjct: 457 HSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSP 516

Query: 239 G-----LFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQAT 293
           G     L  +STT SG +     +   + +T    +PG         TT+L    FGQ +
Sbjct: 517 GSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPG--------STTAL---SFGQES 565

Query: 294 TTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQT 353
           TT ++  + G+T T   P + T    G+ +AS        +  T+   A  T  GL G++
Sbjct: 566 TTFHS--NPGSTHTTLFPDSTTSS--GIVEASTRVHSSTGSPRTTLSPASSTSPGLQGES 621

Query: 354 NTGFGAVGSTLFGNNKLTT----FGSSTTSAPSFGTTSGGLFGFGTNTSGNS----IFGS 405
                   ST    +  +T       STT   S G+T    F   + TSG+S    IF S
Sbjct: 622 TAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHS 681

Query: 406 KPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAP 465
             +P   GT   +   T  G G+++    +          G+   PG +  + T  + +P
Sbjct: 682 --SPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF-YSSP 738

Query: 466 QAPVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQK 525
           ++P     P AS     V ++   S +      S +     + P   EE     + +   
Sbjct: 739 RSPTTTLSP-ASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGS 797

Query: 526 ALTTPTHYKLT-----PRPAT-RVRPKALQTTGTAKSHLFDGLDDD 565
             TT   +  T       P T   RP +  TT   +     GL ++
Sbjct: 798 TETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEE 843



 Score = 65.1 bits (157), Expect = 6e-10
 Identities = 129/553 (23%), Positives = 205/553 (37%), Gaps = 89/553 (16%)

Query: 19   TTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTG 78
            TT+  G+ +    +S G+ GT    + + T GL G S          S  S  +T T+T 
Sbjct: 863  TTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGEST--------PSRLSPSSTETTTL 914

Query: 79   FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSN 138
             G  T+          +   T+ ++S  +  A   P        +T+S G+   ++T+ +
Sbjct: 915  PGSPTTP-------SLSEKSTTFYTSPRSPDATLSP-------ATTTSSGVSEESSTSHS 960

Query: 139  PFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESK 198
              GST  + F  S+ T+  +      +   G+     +  ST  S+  Q  T        
Sbjct: 961  QPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGD 1020

Query: 199  SLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATG-----LFSSSTTNSGFAYG 253
            +   L  +D                T+GL  +S  T S+TG     L  +S+T++G    
Sbjct: 1021 TETTLLPDD--------------TITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEE 1066

Query: 254  QNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPST 313
                    S++    +P G      + +T+  S+P    ++T  T FS  +T T+G+   
Sbjct: 1067 STTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRP----SSTPTTHFSASST-TLGRSEE 1121

Query: 314  NTMGLFGVTQASQPG----GLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFG--N 367
            +T      T  S PG     LF T + TS      T + +   +       GST     +
Sbjct: 1122 ST------TVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLS 1175

Query: 368  NKLTTFGSS-----TTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGT 422
             K TTF SS     TT +P+  TTS G+    T         S   PG+  T    G  T
Sbjct: 1176 EKSTTFYSSPRSPDTTLSPA-STTSSGVSEESTT--------SHSRPGSTHTTAFPGSTT 1226

Query: 423  ALGAGQASLFGNNQP-KIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQ 481
              G  Q S   ++ P      L  G+  A      + T           L   N +A+  
Sbjct: 1227 MPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGL 1286

Query: 482  AVLQQHINSLTYSPF------------GDSPLFRNPMSDPKKKEER-LKPTNPAAQKALT 528
                  ++S T SP             G+S  F+   S P  K+     PT  +A   L+
Sbjct: 1287 LEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQ---SWPSSKDTMPAPPTTTSAFVELS 1343

Query: 529  TPTHYKLTPRPAT 541
            T +H   +  P T
Sbjct: 1344 TTSHGSPSSTPTT 1356



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 108/428 (25%), Positives = 171/428 (39%), Gaps = 70/428 (16%)

Query: 19   TTSTFGQNTGFGT--TSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTS 76
            +++T G++    T  +S GA GT+ F + + T  L G   T P     T + + P ++T+
Sbjct: 1112 SSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTT 1171

Query: 77   TGFG-----FGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKP-----TGFGNFGT---- 122
             G       F +S  + +T    AST TS   S+ +  + ++P     T F    T    
Sbjct: 1172 AGLSEKSTTFYSSPRSPDTTLSPAST-TSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGV 1230

Query: 123  ---STSSGGLFGTTNTTSNPFGSTSGSLFGPSS--FTAAPTGTTIKFNPPTGTDT-MVKA 176
               ST+S    G+T+TT +P GST+ S  GP S  F ++P  T     P   T + +++A
Sbjct: 1231 SQESTASHSSPGSTDTTLSP-GSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEA 1289

Query: 177  GVSTNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSS----P 232
                + ST     T                    +  G   + G  TT   + SS    P
Sbjct: 1290 STPVHSSTGSPHTT-------------------LSPAGSTTRQGESTTFQSWPSSKDTMP 1330

Query: 233  ATSSATGLF-SSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQ 291
            A  + T  F   STT+ G       T F  S+T  G         +++++T++ S P   
Sbjct: 1331 APPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLG---------RSEESTTVHSSPVAT 1381

Query: 292  ATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFG 351
            ATT      +   TS + + ST      G TQ      +    ++T++G +  + T    
Sbjct: 1382 ATTPSP---ARSTTSGLVEESTAYHSSPGSTQT-----MHFPESSTASGRSEESRTSHSS 1433

Query: 352  QTNTGFGAVGSTLFGNNKLTTFGSS-----TTSAPSFGTTSGGLFGFGTNTSGNSIFGSK 406
             T+T      +T     + T++ SS     TT  P   TTSG       + S     G  
Sbjct: 1434 TTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGIT 1493

Query: 407  PAPGTLGT 414
            P P    T
Sbjct: 1494 PLPAHFTT 1501



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 124/510 (24%), Positives = 191/510 (37%), Gaps = 67/510 (13%)

Query: 28   GFGTTSGGAFGTSAFGSS--NNTGGLFGNSQTKPG-GLFGTSSFSQPATSTSTGFGFGTS 84
            G  TT G +  ++ F SS  + T  L   S T  G G   T+S SQP ++ ST     T+
Sbjct: 720  GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTT 779

Query: 85   TG----TANTLFGTA--STGTSLFS-SQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTS 137
            T      + T++ ++  ST T++F  S   +    +PT F +   ST +  LF   +TTS
Sbjct: 780  TPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTT-LFTEDSTTS 838

Query: 138  NPFGSTSGSLFGPSSFTAAPTG-----TTIKFNPPTGTDTMVKAGVSTNISTKHQCITAM 192
               G T  S   P S  +  TG     TT      + T         T +S      + +
Sbjct: 839  ---GLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 895

Query: 193  KEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGS--------SPATSSATGLFSSS 244
                + S       +       P     +  +T  + S        SPAT++++G+   S
Sbjct: 896  VGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 955

Query: 245  TTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKP-------FGQATTTQN 297
            +T+       + TAF  STT    +        +Q +T     P        GQ +TT +
Sbjct: 956  STSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFH 1015

Query: 298  TGFSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLF------- 350
            +  S G+T T   P        G+ +AS P      + +T+   A  T  GL        
Sbjct: 1016 S--SPGDTETTLLPDDTITS--GLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQ 1071

Query: 351  ---GQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPS--FGTTSGGLFGFGTNTSGNSIFGS 405
                 ++T     G+T       TT+ S  +S P+  F  +S  L   G +    ++  S
Sbjct: 1072 SWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTL---GRSEESTTVHSS 1128

Query: 406  KPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTT-----ATL 460
               PG  GT L   F T              P   G   T A   PG  TT      +T 
Sbjct: 1129 ---PGATGTAL---FPTRSATSVLVGEPTTSPISSGSTETTAL--PGSTTTAGLSEKSTT 1180

Query: 461  GFGAPQAPVALTDPNASAAQQAVLQQHINS 490
             + +P++P     P AS     V ++   S
Sbjct: 1181 FYSSPRSPDTTLSP-ASTTSSGVSEESTTS 1209



 Score = 38.1 bits (87), Expect = 0.078
 Identities = 138/647 (21%), Positives = 231/647 (35%), Gaps = 104/647 (16%)

Query: 71  PATSTSTGFGFGTST---GTANTLFGTASTGTSL-FSSQNNAFAQNKPTGFGNFGT---- 122
           P +ST++G    ++T    T +T   T ST  +L  +S +++    + T F +  T    
Sbjct: 4   PESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGR 63

Query: 123 ---STSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVS 179
              S +S        TT  P GST   L G S+ +   +G+      P  T    K G+S
Sbjct: 64  SEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGST---TKPGLS 120

Query: 180 TNISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATG 239
              +T                       + ++ + P        TT L    PA+ +++G
Sbjct: 121 EKSTT-----------------------FYSSPRSPD-------TTHL----PASMTSSG 146

Query: 240 LFSSSTTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTG 299
           +   STT+       + TAF  ST    T PG      +Q++T+  S P G   TT + G
Sbjct: 147 VSEESTTSHSRPGSTHTTAFPGST----TMPG-----LSQESTASHSSP-GPTDTTLSPG 196

Query: 300 FSFGNTSTIGQPSTNTMGLFGVTQASQPGGLFGT--ATNTSTGTAFGTGTGLFGQT---N 354
            +    S++G   T        T  S+PG    T    NT+          +   T   +
Sbjct: 197 ST--TASSLGPEYT--------TFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPH 246

Query: 355 TGFGAVGSTLFGNNKLT--TFGSSTTSAPSFGTTSGGLFGFGTNTSG--NSIFGSKPAPG 410
           T     GST       T  ++ SS  + P+  TT+       T + G  +SI  +  +  
Sbjct: 247 TTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISAR 306

Query: 411 TLGTGL---GAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQA 467
           +  +GL      + ++ G+ Q   F    P+     G G       ++TT T+   AP  
Sbjct: 307 STTSGLVEESTTYHSSPGSTQTMHF----PESDTTSGRGEESTTSHSSTTHTIS-SAPST 361

Query: 468 PVALTDPNASAAQQAVLQQHINSLTYSPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKAL 527
             AL +   S            S   + F DS        +          T      A 
Sbjct: 362 TSALVEEPTS------YHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPAR 415

Query: 528 TTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPKKSIKKLVLKN 587
           +T T   L     + +   +++TT    S    GL +   +  +    P  ++      +
Sbjct: 416 ST-TSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTS 474

Query: 588 LNNSNLFSPVNRDSENLASPSEYPENGERFSFLSKPVDENHQQDGDEDSLVSHFYTNPIA 647
              S   S  +R        + +P++      LS+    +H   G  D+ +      P +
Sbjct: 475 SGVSE-ESTTSRSRPGSTHTTAFPDS-TTTPGLSRHSTTSHSSPGSTDTTLL-----PAS 527

Query: 648 KPIPQTPESAGNKHSNSNSVDDTIVALNMRAALRNGLEGSSEETSFH 694
                  + +   HS+S S  DT ++     AL  G     E T+FH
Sbjct: 528 TTTSGPSQESTTSHSSSGST-DTALSPGSTTALSFG----QESTTFH 569


>gi|24497609 nucleoporin 62kDa [Homo sapiens]
          Length = 522

 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 102/385 (26%), Positives = 143/385 (37%), Gaps = 76/385 (19%)

Query: 7   GTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTS 66
           G P GG T G   T+T    TGF      +F TS  G  N        + T   GLF  +
Sbjct: 10  GAPTGGFTFGTAKTATTTPATGF------SFSTSGTGGFNFGAPFQPATSTPSTGLFSLA 63

Query: 67  SFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAF--AQNKPTGFGNFGTST 124
           +   PAT T TGF FGT+T  +     +   G S  +  N A   A   P+GFG  G+S 
Sbjct: 64  T-QTPATQT-TGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFG-LGSSN 120

Query: 125 SSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIST 184
            +  +  T   TS+   + +G +FGPS+ + AP  T+  F+  TG  T   +G       
Sbjct: 121 LTNAISST--VTSSQGTAPTGFVFGPSTTSVAPATTSGGFS-FTGGSTAQPSG------- 170

Query: 185 KHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSS 244
                                  +     G   Q  A  T     ++PA ++A     ++
Sbjct: 171 -----------------------FNIGSAGNSAQPTAPATLPFTPATPAATTAGATQPAA 207

Query: 245 TTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGN 304
            T          TA  TST                   SLF+      T++  TG S   
Sbjct: 208 PT---------PTATITST-----------------GPSLFASIATAPTSSATTGLSLCT 241

Query: 305 -TSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363
             +T G P+  T G         PG   GT+T TST  A  T T     + TGF      
Sbjct: 242 PVTTAGAPTAGTQGF----SLKAPGAASGTSTTTST-AATATATTTSSSSTTGFALNLKP 296

Query: 364 LFGNNKLTTFGSSTTSAPSFGTTSG 388
           L      +   ++ T+ P  G  +G
Sbjct: 297 LAPAGIPSNTAAAVTAPPGPGAAAG 321



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 88/310 (28%), Positives = 117/310 (37%), Gaps = 49/310 (15%)

Query: 221 AGTTTGLFGS--SPATSS-ATGLFS-----SSTTNSGFAYGQNKTAFG------------ 260
           +GT    FG+   PATS+ +TGLFS      +T  +GF +G    A G            
Sbjct: 37  SGTGGFNFGAPFQPATSTPSTGLFSLATQTPATQTTGFTFGTATLASGGTGFSLGIGASK 96

Query: 261 -----TSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNT 315
                T+ T    NP G FG  +   T+  S     +  T  TGF FG ++T   P+T T
Sbjct: 97  LNLSNTAATPAMANPSG-FGLGSSNLTNAISSTVTSSQGTAPTGFVFGPSTTSVAPAT-T 154

Query: 316 MGLFGVTQAS--QPGGL-FGTATNTSTGTAFGT--------GTGLFGQTNTGFGAVGSTL 364
            G F  T  S  QP G   G+A N++  TA  T             G T        +T+
Sbjct: 155 SGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPATPAATTAGATQPAAPTPTATI 214

Query: 365 FGNNKLTTFGSSTTSAPSFGTTSGGL----FGFGTNTSGNSIFGSKPAPGTLGTGLGAGF 420
                 + F S  T+  S  TT   L       G  T+G   F  K APG      G   
Sbjct: 215 TSTGP-SLFASIATAPTSSATTGLSLCTPVTTAGAPTAGTQGFSLK-APGAAS---GTST 269

Query: 421 GTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQ 480
            T+  A   +   ++    G  L        G  + TA     AP  P A     AS+A 
Sbjct: 270 TTSTAATATATTTSSSSTTGFALNLKPLAPAGIPSNTAA-AVTAPPGPGAAAGAAASSAM 328

Query: 481 -QAVLQQHIN 489
             A L+  IN
Sbjct: 329 TYAQLESLIN 338



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 42/151 (27%), Positives = 53/151 (35%), Gaps = 20/151 (13%)

Query: 319 FGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTT 378
           FG T A   G  FGTA   +T  A G      G     FGA                   
Sbjct: 6   FGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGA------------------P 47

Query: 379 SAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGN-NQP 437
             P+  T S GLF   T T      G      TL +G G GF   +GA + +L      P
Sbjct: 48  FQPATSTPSTGLFSLATQTPATQTTGFTFGTATLASG-GTGFSLGIGASKLNLSNTAATP 106

Query: 438 KIGGPLGTGAFGAPGFNTTTATLGFGAPQAP 468
            +  P G G   +   N  ++T+      AP
Sbjct: 107 AMANPSGFGLGSSNLTNAISSTVTSSQGTAP 137



 Score = 38.1 bits (87), Expect = 0.078
 Identities = 56/208 (26%), Positives = 76/208 (36%), Gaps = 29/208 (13%)

Query: 5   SFGTPF--GGGTG---GFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFG----NS 55
           +FGT     GGTG   G G +     NT          G    GSSN T  +      + 
Sbjct: 75  TFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFG-LGSSNLTNAISSTVTSSQ 133

Query: 56  QTKPGG-LFGTSSFSQPATSTSTGFGF---------GTSTGTANTLFGTASTGTSLFSSQ 105
            T P G +FG S+ S    +TS GF F         G + G+A       +  T  F+  
Sbjct: 134 GTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPA 193

Query: 106 NNA---FAQNKPTGFGNFGTSTSSG-GLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTT 161
             A       +P       T TS+G  LF +  T      +T  SL  P +   APT  T
Sbjct: 194 TPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLCTPVTTAGAPTAGT 253

Query: 162 IKFN-----PPTGTDTMVKAGVSTNIST 184
             F+       +GT T      +   +T
Sbjct: 254 QGFSLKAPGAASGTSTTTSTAATATATT 281


>gi|24497607 nucleoporin 62kDa [Homo sapiens]
          Length = 522

 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 102/385 (26%), Positives = 143/385 (37%), Gaps = 76/385 (19%)

Query: 7   GTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTS 66
           G P GG T G   T+T    TGF      +F TS  G  N        + T   GLF  +
Sbjct: 10  GAPTGGFTFGTAKTATTTPATGF------SFSTSGTGGFNFGAPFQPATSTPSTGLFSLA 63

Query: 67  SFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAF--AQNKPTGFGNFGTST 124
           +   PAT T TGF FGT+T  +     +   G S  +  N A   A   P+GFG  G+S 
Sbjct: 64  T-QTPATQT-TGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFG-LGSSN 120

Query: 125 SSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIST 184
            +  +  T   TS+   + +G +FGPS+ + AP  T+  F+  TG  T   +G       
Sbjct: 121 LTNAISST--VTSSQGTAPTGFVFGPSTTSVAPATTSGGFS-FTGGSTAQPSG------- 170

Query: 185 KHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSS 244
                                  +     G   Q  A  T     ++PA ++A     ++
Sbjct: 171 -----------------------FNIGSAGNSAQPTAPATLPFTPATPAATTAGATQPAA 207

Query: 245 TTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGN 304
            T          TA  TST                   SLF+      T++  TG S   
Sbjct: 208 PT---------PTATITST-----------------GPSLFASIATAPTSSATTGLSLCT 241

Query: 305 -TSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363
             +T G P+  T G         PG   GT+T TST  A  T T     + TGF      
Sbjct: 242 PVTTAGAPTAGTQGF----SLKAPGAASGTSTTTST-AATATATTTSSSSTTGFALNLKP 296

Query: 364 LFGNNKLTTFGSSTTSAPSFGTTSG 388
           L      +   ++ T+ P  G  +G
Sbjct: 297 LAPAGIPSNTAAAVTAPPGPGAAAG 321



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 88/310 (28%), Positives = 117/310 (37%), Gaps = 49/310 (15%)

Query: 221 AGTTTGLFGS--SPATSS-ATGLFS-----SSTTNSGFAYGQNKTAFG------------ 260
           +GT    FG+   PATS+ +TGLFS      +T  +GF +G    A G            
Sbjct: 37  SGTGGFNFGAPFQPATSTPSTGLFSLATQTPATQTTGFTFGTATLASGGTGFSLGIGASK 96

Query: 261 -----TSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNT 315
                T+ T    NP G FG  +   T+  S     +  T  TGF FG ++T   P+T T
Sbjct: 97  LNLSNTAATPAMANPSG-FGLGSSNLTNAISSTVTSSQGTAPTGFVFGPSTTSVAPAT-T 154

Query: 316 MGLFGVTQAS--QPGGL-FGTATNTSTGTAFGT--------GTGLFGQTNTGFGAVGSTL 364
            G F  T  S  QP G   G+A N++  TA  T             G T        +T+
Sbjct: 155 SGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPATPAATTAGATQPAAPTPTATI 214

Query: 365 FGNNKLTTFGSSTTSAPSFGTTSGGL----FGFGTNTSGNSIFGSKPAPGTLGTGLGAGF 420
                 + F S  T+  S  TT   L       G  T+G   F  K APG      G   
Sbjct: 215 TSTGP-SLFASIATAPTSSATTGLSLCTPVTTAGAPTAGTQGFSLK-APGAAS---GTST 269

Query: 421 GTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQ 480
            T+  A   +   ++    G  L        G  + TA     AP  P A     AS+A 
Sbjct: 270 TTSTAATATATTTSSSSTTGFALNLKPLAPAGIPSNTAA-AVTAPPGPGAAAGAAASSAM 328

Query: 481 -QAVLQQHIN 489
             A L+  IN
Sbjct: 329 TYAQLESLIN 338



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 42/151 (27%), Positives = 53/151 (35%), Gaps = 20/151 (13%)

Query: 319 FGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTT 378
           FG T A   G  FGTA   +T  A G      G     FGA                   
Sbjct: 6   FGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGA------------------P 47

Query: 379 SAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGN-NQP 437
             P+  T S GLF   T T      G      TL +G G GF   +GA + +L      P
Sbjct: 48  FQPATSTPSTGLFSLATQTPATQTTGFTFGTATLASG-GTGFSLGIGASKLNLSNTAATP 106

Query: 438 KIGGPLGTGAFGAPGFNTTTATLGFGAPQAP 468
            +  P G G   +   N  ++T+      AP
Sbjct: 107 AMANPSGFGLGSSNLTNAISSTVTSSQGTAP 137



 Score = 38.1 bits (87), Expect = 0.078
 Identities = 56/208 (26%), Positives = 76/208 (36%), Gaps = 29/208 (13%)

Query: 5   SFGTPF--GGGTG---GFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFG----NS 55
           +FGT     GGTG   G G +     NT          G    GSSN T  +      + 
Sbjct: 75  TFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFG-LGSSNLTNAISSTVTSSQ 133

Query: 56  QTKPGG-LFGTSSFSQPATSTSTGFGF---------GTSTGTANTLFGTASTGTSLFSSQ 105
            T P G +FG S+ S    +TS GF F         G + G+A       +  T  F+  
Sbjct: 134 GTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPA 193

Query: 106 NNA---FAQNKPTGFGNFGTSTSSG-GLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTT 161
             A       +P       T TS+G  LF +  T      +T  SL  P +   APT  T
Sbjct: 194 TPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLCTPVTTAGAPTAGT 253

Query: 162 IKFN-----PPTGTDTMVKAGVSTNIST 184
             F+       +GT T      +   +T
Sbjct: 254 QGFSLKAPGAASGTSTTTSTAATATATT 281


>gi|24497605 nucleoporin 62kDa [Homo sapiens]
          Length = 522

 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 102/385 (26%), Positives = 143/385 (37%), Gaps = 76/385 (19%)

Query: 7   GTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTS 66
           G P GG T G   T+T    TGF      +F TS  G  N        + T   GLF  +
Sbjct: 10  GAPTGGFTFGTAKTATTTPATGF------SFSTSGTGGFNFGAPFQPATSTPSTGLFSLA 63

Query: 67  SFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAF--AQNKPTGFGNFGTST 124
           +   PAT T TGF FGT+T  +     +   G S  +  N A   A   P+GFG  G+S 
Sbjct: 64  T-QTPATQT-TGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFG-LGSSN 120

Query: 125 SSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIST 184
            +  +  T   TS+   + +G +FGPS+ + AP  T+  F+  TG  T   +G       
Sbjct: 121 LTNAISST--VTSSQGTAPTGFVFGPSTTSVAPATTSGGFS-FTGGSTAQPSG------- 170

Query: 185 KHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSS 244
                                  +     G   Q  A  T     ++PA ++A     ++
Sbjct: 171 -----------------------FNIGSAGNSAQPTAPATLPFTPATPAATTAGATQPAA 207

Query: 245 TTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGN 304
            T          TA  TST                   SLF+      T++  TG S   
Sbjct: 208 PT---------PTATITST-----------------GPSLFASIATAPTSSATTGLSLCT 241

Query: 305 -TSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363
             +T G P+  T G         PG   GT+T TST  A  T T     + TGF      
Sbjct: 242 PVTTAGAPTAGTQGF----SLKAPGAASGTSTTTST-AATATATTTSSSSTTGFALNLKP 296

Query: 364 LFGNNKLTTFGSSTTSAPSFGTTSG 388
           L      +   ++ T+ P  G  +G
Sbjct: 297 LAPAGIPSNTAAAVTAPPGPGAAAG 321



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 88/310 (28%), Positives = 117/310 (37%), Gaps = 49/310 (15%)

Query: 221 AGTTTGLFGS--SPATSS-ATGLFS-----SSTTNSGFAYGQNKTAFG------------ 260
           +GT    FG+   PATS+ +TGLFS      +T  +GF +G    A G            
Sbjct: 37  SGTGGFNFGAPFQPATSTPSTGLFSLATQTPATQTTGFTFGTATLASGGTGFSLGIGASK 96

Query: 261 -----TSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNT 315
                T+ T    NP G FG  +   T+  S     +  T  TGF FG ++T   P+T T
Sbjct: 97  LNLSNTAATPAMANPSG-FGLGSSNLTNAISSTVTSSQGTAPTGFVFGPSTTSVAPAT-T 154

Query: 316 MGLFGVTQAS--QPGGL-FGTATNTSTGTAFGT--------GTGLFGQTNTGFGAVGSTL 364
            G F  T  S  QP G   G+A N++  TA  T             G T        +T+
Sbjct: 155 SGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPATPAATTAGATQPAAPTPTATI 214

Query: 365 FGNNKLTTFGSSTTSAPSFGTTSGGL----FGFGTNTSGNSIFGSKPAPGTLGTGLGAGF 420
                 + F S  T+  S  TT   L       G  T+G   F  K APG      G   
Sbjct: 215 TSTGP-SLFASIATAPTSSATTGLSLCTPVTTAGAPTAGTQGFSLK-APGAAS---GTST 269

Query: 421 GTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQ 480
            T+  A   +   ++    G  L        G  + TA     AP  P A     AS+A 
Sbjct: 270 TTSTAATATATTTSSSSTTGFALNLKPLAPAGIPSNTAA-AVTAPPGPGAAAGAAASSAM 328

Query: 481 -QAVLQQHIN 489
             A L+  IN
Sbjct: 329 TYAQLESLIN 338



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 42/151 (27%), Positives = 53/151 (35%), Gaps = 20/151 (13%)

Query: 319 FGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTT 378
           FG T A   G  FGTA   +T  A G      G     FGA                   
Sbjct: 6   FGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGA------------------P 47

Query: 379 SAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGN-NQP 437
             P+  T S GLF   T T      G      TL +G G GF   +GA + +L      P
Sbjct: 48  FQPATSTPSTGLFSLATQTPATQTTGFTFGTATLASG-GTGFSLGIGASKLNLSNTAATP 106

Query: 438 KIGGPLGTGAFGAPGFNTTTATLGFGAPQAP 468
            +  P G G   +   N  ++T+      AP
Sbjct: 107 AMANPSGFGLGSSNLTNAISSTVTSSQGTAP 137



 Score = 38.1 bits (87), Expect = 0.078
 Identities = 56/208 (26%), Positives = 76/208 (36%), Gaps = 29/208 (13%)

Query: 5   SFGTPF--GGGTG---GFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFG----NS 55
           +FGT     GGTG   G G +     NT          G    GSSN T  +      + 
Sbjct: 75  TFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFG-LGSSNLTNAISSTVTSSQ 133

Query: 56  QTKPGG-LFGTSSFSQPATSTSTGFGF---------GTSTGTANTLFGTASTGTSLFSSQ 105
            T P G +FG S+ S    +TS GF F         G + G+A       +  T  F+  
Sbjct: 134 GTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPA 193

Query: 106 NNA---FAQNKPTGFGNFGTSTSSG-GLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTT 161
             A       +P       T TS+G  LF +  T      +T  SL  P +   APT  T
Sbjct: 194 TPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLCTPVTTAGAPTAGT 253

Query: 162 IKFN-----PPTGTDTMVKAGVSTNIST 184
             F+       +GT T      +   +T
Sbjct: 254 QGFSLKAPGAASGTSTTTSTAATATATT 281


>gi|24497603 nucleoporin 62kDa [Homo sapiens]
          Length = 522

 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 102/385 (26%), Positives = 143/385 (37%), Gaps = 76/385 (19%)

Query: 7   GTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTS 66
           G P GG T G   T+T    TGF      +F TS  G  N        + T   GLF  +
Sbjct: 10  GAPTGGFTFGTAKTATTTPATGF------SFSTSGTGGFNFGAPFQPATSTPSTGLFSLA 63

Query: 67  SFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAF--AQNKPTGFGNFGTST 124
           +   PAT T TGF FGT+T  +     +   G S  +  N A   A   P+GFG  G+S 
Sbjct: 64  T-QTPATQT-TGFTFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFG-LGSSN 120

Query: 125 SSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIST 184
            +  +  T   TS+   + +G +FGPS+ + AP  T+  F+  TG  T   +G       
Sbjct: 121 LTNAISST--VTSSQGTAPTGFVFGPSTTSVAPATTSGGFS-FTGGSTAQPSG------- 170

Query: 185 KHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSS 244
                                  +     G   Q  A  T     ++PA ++A     ++
Sbjct: 171 -----------------------FNIGSAGNSAQPTAPATLPFTPATPAATTAGATQPAA 207

Query: 245 TTNSGFAYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGN 304
            T          TA  TST                   SLF+      T++  TG S   
Sbjct: 208 PT---------PTATITST-----------------GPSLFASIATAPTSSATTGLSLCT 241

Query: 305 -TSTIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGST 363
             +T G P+  T G         PG   GT+T TST  A  T T     + TGF      
Sbjct: 242 PVTTAGAPTAGTQGF----SLKAPGAASGTSTTTST-AATATATTTSSSSTTGFALNLKP 296

Query: 364 LFGNNKLTTFGSSTTSAPSFGTTSG 388
           L      +   ++ T+ P  G  +G
Sbjct: 297 LAPAGIPSNTAAAVTAPPGPGAAAG 321



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 88/310 (28%), Positives = 117/310 (37%), Gaps = 49/310 (15%)

Query: 221 AGTTTGLFGS--SPATSS-ATGLFS-----SSTTNSGFAYGQNKTAFG------------ 260
           +GT    FG+   PATS+ +TGLFS      +T  +GF +G    A G            
Sbjct: 37  SGTGGFNFGAPFQPATSTPSTGLFSLATQTPATQTTGFTFGTATLASGGTGFSLGIGASK 96

Query: 261 -----TSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNT 315
                T+ T    NP G FG  +   T+  S     +  T  TGF FG ++T   P+T T
Sbjct: 97  LNLSNTAATPAMANPSG-FGLGSSNLTNAISSTVTSSQGTAPTGFVFGPSTTSVAPAT-T 154

Query: 316 MGLFGVTQAS--QPGGL-FGTATNTSTGTAFGT--------GTGLFGQTNTGFGAVGSTL 364
            G F  T  S  QP G   G+A N++  TA  T             G T        +T+
Sbjct: 155 SGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPATPAATTAGATQPAAPTPTATI 214

Query: 365 FGNNKLTTFGSSTTSAPSFGTTSGGL----FGFGTNTSGNSIFGSKPAPGTLGTGLGAGF 420
                 + F S  T+  S  TT   L       G  T+G   F  K APG      G   
Sbjct: 215 TSTGP-SLFASIATAPTSSATTGLSLCTPVTTAGAPTAGTQGFSLK-APGAAS---GTST 269

Query: 421 GTALGAGQASLFGNNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQ 480
            T+  A   +   ++    G  L        G  + TA     AP  P A     AS+A 
Sbjct: 270 TTSTAATATATTTSSSSTTGFALNLKPLAPAGIPSNTAA-AVTAPPGPGAAAGAAASSAM 328

Query: 481 -QAVLQQHIN 489
             A L+  IN
Sbjct: 329 TYAQLESLIN 338



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 42/151 (27%), Positives = 53/151 (35%), Gaps = 20/151 (13%)

Query: 319 FGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTT 378
           FG T A   G  FGTA   +T  A G      G     FGA                   
Sbjct: 6   FGGTGAPTGGFTFGTAKTATTTPATGFSFSTSGTGGFNFGA------------------P 47

Query: 379 SAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGN-NQP 437
             P+  T S GLF   T T      G      TL +G G GF   +GA + +L      P
Sbjct: 48  FQPATSTPSTGLFSLATQTPATQTTGFTFGTATLASG-GTGFSLGIGASKLNLSNTAATP 106

Query: 438 KIGGPLGTGAFGAPGFNTTTATLGFGAPQAP 468
            +  P G G   +   N  ++T+      AP
Sbjct: 107 AMANPSGFGLGSSNLTNAISSTVTSSQGTAP 137



 Score = 38.1 bits (87), Expect = 0.078
 Identities = 56/208 (26%), Positives = 76/208 (36%), Gaps = 29/208 (13%)

Query: 5   SFGTPF--GGGTG---GFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTGGLFG----NS 55
           +FGT     GGTG   G G +     NT          G    GSSN T  +      + 
Sbjct: 75  TFGTATLASGGTGFSLGIGASKLNLSNTAATPAMANPSGFG-LGSSNLTNAISSTVTSSQ 133

Query: 56  QTKPGG-LFGTSSFSQPATSTSTGFGF---------GTSTGTANTLFGTASTGTSLFSSQ 105
            T P G +FG S+ S    +TS GF F         G + G+A       +  T  F+  
Sbjct: 134 GTAPTGFVFGPSTTSVAPATTSGGFSFTGGSTAQPSGFNIGSAGNSAQPTAPATLPFTPA 193

Query: 106 NNA---FAQNKPTGFGNFGTSTSSG-GLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTT 161
             A       +P       T TS+G  LF +  T      +T  SL  P +   APT  T
Sbjct: 194 TPAATTAGATQPAAPTPTATITSTGPSLFASIATAPTSSATTGLSLCTPVTTAGAPTAGT 253

Query: 162 IKFN-----PPTGTDTMVKAGVSTNIST 184
             F+       +GT T      +   +T
Sbjct: 254 QGFSLKAPGAASGTSTTTSTAATATATT 281


>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
            sapiens]
          Length = 2134

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 108/412 (26%), Positives = 149/412 (36%), Gaps = 54/412 (13%)

Query: 65   TSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTS--LFSSQNNAFAQN--KPTGFGNF 120
            +++ S PA +TS+    GT+ G     F T  T TS  + S+  NA       PT  G  
Sbjct: 1711 STAASIPAITTSSSETTGTTLGPLTEPFTTGITETSVPIISTSGNAGMTGVVSPTVTGAS 1770

Query: 121  GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180
            G + ++GG+   T   ++   S        S  T A  G +       G       GVS 
Sbjct: 1771 GMAGTTGGVDAATTGAASENTSERAGTPRVSGETPAVGGGSTPGEAGPGATVSGSTGVSA 1830

Query: 181  NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240
               T     +A     SKS              GP      G T+    SS   S  TG 
Sbjct: 1831 GSITASPGASATSSESSKS-----------GTTGPSVGGKTGATSSEATSSEGMSGVTGQ 1879

Query: 241  FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPG-GLFGQQNQQTTSLFSKPFGQATTT---- 295
               ST  S        +  G+S  G  T P  G  G  +  TT      +G   TT    
Sbjct: 1880 SLGSTAGSDSEITAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTE-----WGNVATTGAAG 1934

Query: 296  QNTGFSFGNT-----STIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLF 350
            +NT  + G+T     +T    S NT G  G T  + PG    TA + +   + G   G  
Sbjct: 1935 ENTSGALGSTEGSVEATTSAGSGNTAGTSG-TGDTGPGN---TAVSGTPVVSPGATPGAP 1990

Query: 351  GQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSF----------GTTSGGLFGFGTNTSGN 400
            G +  G   +G+T FG +  +   S T   P+F           TTS  +       S  
Sbjct: 1991 GSSTPGEADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVSAASTTSSPVSKHTDAASAT 2050

Query: 401  SIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGGPLGTGAFGAPG 452
            ++  S   PGT GT  GA  G  + +G +S              TGA   PG
Sbjct: 2051 AVTISGSKPGTPGTPGGATSGGKITSGWSS----------SGTSTGASNTPG 2092



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 90/420 (21%), Positives = 142/420 (33%), Gaps = 68/420 (16%)

Query: 156  APTGTTIKFNPPTGTD--------TMVKAGVSTNIS----------TKHQCITAMKEYES 197
            APT +T   +  T T         T+V  G ST  S          T    +  + E  +
Sbjct: 1680 APTNSTFAVSTTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPLTEPFT 1739

Query: 198  KSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPAT----SSATGLFSSSTTNSGFAYG 253
              + E  +     +       V + T TG  G +  T    ++ TG  S +T+      G
Sbjct: 1740 TGITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERA---G 1796

Query: 254  QNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPST 313
              + +  T   G G+ PG               +    AT + +TG S G+        T
Sbjct: 1797 TPRVSGETPAVGGGSTPG---------------EAGPGATVSGSTGVSAGSI-------T 1834

Query: 314  NTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTF 373
             + G    +  S   G  G +    TG      T   G +     ++GST   ++++T  
Sbjct: 1835 ASPGASATSSESSKSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAK 1894

Query: 374  GSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFG 433
             S T S+P    T       G  + G + +G+    G  G       G+  G+ +A+   
Sbjct: 1895 TSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSA 1954

Query: 434  NNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTY 493
             +     G  GTG  G PG    + T        P A   P +S   +A        +  
Sbjct: 1955 GS-GNTAGTSGTGDTG-PGNTAVSGTPVVSPGATPGA---PGSSTPGEA-------DIGN 2002

Query: 494  SPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPATRVRPKALQTTGT 553
            + FG S          K   + L   NPA  +   T +    T  P ++    A  T  T
Sbjct: 2003 TSFGKS---------GKSGHDSLTVLNPAFLRRTPTVSAASTTSSPVSKHTDAASATAVT 2053



 Score = 44.7 bits (104), Expect = 8e-04
 Identities = 56/190 (29%), Positives = 71/190 (37%), Gaps = 48/190 (25%)

Query: 7    GTP--FGGGT---GGFGTTSTFGQNTG--FGTTSGGAFGTSAFGSSNNTGGLFGNSQTKP 59
            G+P  F GGT   G   TT   G+NT    G+T G    T++ GS N T G  G   T P
Sbjct: 1912 GSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGN-TAGTSGTGDTGP 1970

Query: 60   GG--LFGTSSFSQPATSTSTGFGFGTSTGTANTLFG------------------------ 93
            G   + GT   S  AT  + G          NT FG                        
Sbjct: 1971 GNTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTV 2030

Query: 94   -TASTGTSLFSSQNNA-------FAQNKPTGFGNFGTSTSSGGLF------GTTNTTSNP 139
              AST +S  S   +A        + +KP   G  G +TS G +       GT+   SN 
Sbjct: 2031 SAASTTSSPVSKHTDAASATAVTISGSKPGTPGTPGGATSGGKITSGWSSSGTSTGASNT 2090

Query: 140  FGSTSGSLFG 149
             G  S +L G
Sbjct: 2091 PGEISKALKG 2100



 Score = 38.5 bits (88), Expect = 0.060
 Identities = 92/399 (23%), Positives = 136/399 (34%), Gaps = 55/399 (13%)

Query: 2   FNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAF-GTSAFGSSNNTGGLF-------G 53
           F+   G P G      G +   G +    T  GG F G+S+ G S+    LF       G
Sbjct: 98  FSLGLGAP-GKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATG 156

Query: 54  NSQTKPGGLF---GTSSFSQPATSTST--GFGFGTSTGTANTLFGTASTGTSLF------ 102
             + K    +    + S   PA ST+T  G GF +S  + +  FG   +           
Sbjct: 157 EDEDKSRERWDAGNSRSEDSPADSTNTRYGAGFSSSGASLDVGFGWGISDEKGLEVSKAD 216

Query: 103 --SSQNNAFAQNKPTGFGNFGTSTSSGGL----------FGTTNTTSNPFGSTSGSLFGP 150
              ++ +  A  +   FG     T S GL          FG   + SN FG T     G 
Sbjct: 217 GRETRGSGSAGGETIVFGPDAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDT-----GI 271

Query: 151 SSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQA 210
           SS T     T+      +G    +  G  T+  +++Q +         +L +   E +  
Sbjct: 272 SSKTVEGNQTS-----SSGGSVSIDLG-DTSFRSENQFVGGGSLNSISNLWDSGQEGFGI 325

Query: 211 NRKGPQNQVGA-GTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTN 269
           N  G     G+     G  G    +SS+ G+  S      F  G  K   G      G+ 
Sbjct: 326 NEIGGNGMSGSVSAEAGFKGFGSDSSSSVGMLESLE----FGLGGKKVGAGFDFKYSGSR 381

Query: 270 PGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGG 329
             G  G +  +     ++    +   +N GF        GQ    T G     Q+S    
Sbjct: 382 KFG--GNELSENGIKVTRESSSSDLAENLGFGL---EKFGQKGFGTSGSGWNEQSSSKSD 436

Query: 330 LFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNN 368
           + G A   S    FG G    G     F   GS   G+N
Sbjct: 437 VSG-AVEKSWLFEFGLGE-TKGGAEFNFRDSGSNQSGDN 473



 Score = 33.1 bits (74), Expect = 2.5
 Identities = 47/216 (21%), Positives = 73/216 (33%), Gaps = 41/216 (18%)

Query: 210 ANRKGPQNQVGAGTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTN 269
           ++R  P   +G G        S  +  A G  S  T   GF YG + +            
Sbjct: 91  SDRTKPFFSLGLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSG----------- 139

Query: 270 PGGLFGQQNQQTTSLFSKPFGQATTTQNTG---FSFGNTSTIGQPSTNTMGLFGVTQASQ 326
                   + +   LFS  FG     ++     +  GN+ +   P+ +T   +G   +S 
Sbjct: 140 -------DSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPADSTNTRYGAGFSSS 192

Query: 327 PGGL---FGTATNTSTGTAFGTGTG--------------LFGQTNTGFGAVGSTLFGNNK 369
              L   FG   +   G       G              +FG    G G+ G  L     
Sbjct: 193 GASLDVGFGWGISDEKGLEVSKADGRETRGSGSAGGETIVFGPDAVGTGSSGLKLGAGKG 252

Query: 370 LTTFGSSTTSAPSFGTT---SGGLFGFGTNTSGNSI 402
              FG   + + SFG T   S  + G  T++SG S+
Sbjct: 253 DAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSV 288



 Score = 32.3 bits (72), Expect = 4.3
 Identities = 40/162 (24%), Positives = 60/162 (37%), Gaps = 25/162 (15%)

Query: 4   KSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFG---TSAFGSSNNTGGL--------- 51
           + FG    GG G  G+ S      GFG+ S  + G   +  FG      G          
Sbjct: 321 EGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVGMLESLEFGLGGKKVGAGFDFKYSGS 380

Query: 52  --FGNSQTKPGGLFGTSSFSQPATSTSTGFG---FGTSTGTANTLFGTASTG-TSLFSSQ 105
             FG ++    G+  T   S    + + GFG   FG         FGT+ +G     SS+
Sbjct: 381 RKFGGNELSENGIKVTRESSSSDLAENLGFGLEKFGQKG------FGTSGSGWNEQSSSK 434

Query: 106 NNAFAQNKPTGFGNFGTSTSSGGL-FGTTNTTSNPFGSTSGS 146
           ++     + +    FG   + GG  F   ++ SN  G    S
Sbjct: 435 SDVSGAVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNS 476


>gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]
          Length = 1950

 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 103/390 (26%), Positives = 144/390 (36%), Gaps = 44/390 (11%)

Query: 65   TSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTS--LFSSQNNAFAQN--KPTGFGNF 120
            +++ S PA +TS+    GT+ G     F T  T TS  + S+  NA       PT  G  
Sbjct: 1527 STAASIPAITTSSSETTGTTLGPLTEPFTTGITETSVPIISTSGNAGMTGVVSPTVTGAS 1586

Query: 121  GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVST 180
            G + ++GG+   T   ++   S        S  T A  G +       G       GVS 
Sbjct: 1587 GMAGTTGGVDAATTGAASENTSERAGTPRVSGATPAVGGGSTPGEAGPGATVSGSTGVSA 1646

Query: 181  NISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPATSSATGL 240
               T     +A     SKS              GP      G T+    SS   S  TG 
Sbjct: 1647 GSITASPGASATSSESSKS-----------GTTGPSVGGKTGATSSEATSSEGMSGVTGQ 1695

Query: 241  FSSSTTNSGFAYGQNKTAFGTSTTGFGTNPG-GLFGQQNQQTTSLFSKPFGQATTT---- 295
               ST  S        +  G+S  G  T P  G  G  +  TT      +G   TT    
Sbjct: 1696 SLGSTAGSDSEITAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTE-----WGNVATTGAAG 1750

Query: 296  QNTGFSFGNT-----STIGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLF 350
            +NT  + G+T     +T    S NT G  G T  + PG    TA + +   + G   G  
Sbjct: 1751 ENTSGALGSTEGSVEATTSAGSGNTAGTSG-TGDTGPGN---TAVSGTPVVSPGATPGAP 1806

Query: 351  GQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSF----------GTTSGGLFGFGTNTSGN 400
            G +  G   +G+T FG +  +   S T   P+F           TTS  +       S  
Sbjct: 1807 GSSTPGEADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVSAASTTSSPVSKHTDAASAT 1866

Query: 401  SIFGSKPAPGTLGTGLGAGFGTALGAGQAS 430
            ++  S   PGT GT  GA  G  + +G +S
Sbjct: 1867 AVTISGSKPGTPGTPGGATSGGKITSGWSS 1896



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 90/420 (21%), Positives = 142/420 (33%), Gaps = 68/420 (16%)

Query: 156  APTGTTIKFNPPTGTD--------TMVKAGVSTNIS----------TKHQCITAMKEYES 197
            APT +T   +  T T         T+V  G ST  S          T    +  + E  +
Sbjct: 1496 APTNSTFAVSTTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPLTEPFT 1555

Query: 198  KSLEELRLEDYQANRKGPQNQVGAGTTTGLFGSSPAT----SSATGLFSSSTTNSGFAYG 253
              + E  +     +       V + T TG  G +  T    ++ TG  S +T+      G
Sbjct: 1556 TGITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERA---G 1612

Query: 254  QNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPST 313
              + +  T   G G+ PG               +    AT + +TG S G+        T
Sbjct: 1613 TPRVSGATPAVGGGSTPG---------------EAGPGATVSGSTGVSAGSI-------T 1650

Query: 314  NTMGLFGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTF 373
             + G    +  S   G  G +    TG      T   G +     ++GST   ++++T  
Sbjct: 1651 ASPGASATSSESSKSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAK 1710

Query: 374  GSSTTSAPSFGTTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFG 433
             S T S+P    T       G  + G + +G+    G  G       G+  G+ +A+   
Sbjct: 1711 TSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSA 1770

Query: 434  NNQPKIGGPLGTGAFGAPGFNTTTATLGFGAPQAPVALTDPNASAAQQAVLQQHINSLTY 493
             +     G  GTG  G PG    + T        P A   P +S   +A        +  
Sbjct: 1771 GS-GNTAGTSGTGDTG-PGNTAVSGTPVVSPGATPGA---PGSSTPGEA-------DIGN 1818

Query: 494  SPFGDSPLFRNPMSDPKKKEERLKPTNPAAQKALTTPTHYKLTPRPATRVRPKALQTTGT 553
            + FG S          K   + L   NPA  +   T +    T  P ++    A  T  T
Sbjct: 1819 TSFGKS---------GKSGHDSLTVLNPAFLRRTPTVSAASTTSSPVSKHTDAASATAVT 1869



 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 56/190 (29%), Positives = 72/190 (37%), Gaps = 48/190 (25%)

Query: 7    GTP--FGGGT---GGFGTTSTFGQNTG--FGTTSGGAFGTSAFGSSNNTGGLFGNSQTKP 59
            G+P  F GGT   G   TT   G+NT    G+T G    T++ GS N T G  G   T P
Sbjct: 1728 GSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGN-TAGTSGTGDTGP 1786

Query: 60   GG--LFGTSSFSQPATSTSTGFGFGTSTGTANTLFG------------------------ 93
            G   + GT   S  AT  + G          NT FG                        
Sbjct: 1787 GNTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTV 1846

Query: 94   -TASTGTSLFSSQNNA-------FAQNKPTGFGNFGTSTSSGGLF------GTTNTTSNP 139
              AST +S  S   +A        + +KP   G  G +TS G +       GT+  +SN 
Sbjct: 1847 SAASTTSSPVSKHTDAASATAVTISGSKPGTPGTPGGATSGGKITSGWSSSGTSTGSSNT 1906

Query: 140  FGSTSGSLFG 149
             G  S +L G
Sbjct: 1907 PGEISKALKG 1916



 Score = 39.3 bits (90), Expect = 0.035
 Identities = 92/399 (23%), Positives = 136/399 (34%), Gaps = 55/399 (13%)

Query: 2   FNKSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAF-GTSAFGSSNNTGGLF-------G 53
           F+   G P G      G +   G +    T  GG F G+S+ G S+    LF       G
Sbjct: 87  FSLGLGAP-GKAEDKSGDSQDAGSSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATG 145

Query: 54  NSQTKPGGLF---GTSSFSQPATSTST--GFGFGTSTGTANTLFGTASTGTSLF------ 102
             + K    +    + S   PA ST+T  G GF +S  + +  FG   +           
Sbjct: 146 EDEDKSRERWDAGNSRSEDSPADSTNTRYGAGFSSSGASLDVGFGWGISDEKGLEVSKAD 205

Query: 103 --SSQNNAFAQNKPTGFGNFGTSTSSGGL----------FGTTNTTSNPFGSTSGSLFGP 150
              ++ +  A  +   FG     T S GL          FG   + SN FG T     G 
Sbjct: 206 GRETRGSGSAGGETIVFGPDAVGTGSSGLKLGAGKGDAAFGFEVSDSNSFGDT-----GI 260

Query: 151 SSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLEELRLEDYQA 210
           SS T     T+      +G    +  G  T+  +++Q +         +L +   E +  
Sbjct: 261 SSKTVEGNQTS-----SSGGSVSIDLG-DTSFRSENQFVGGGSLNSISNLWDSGQEGFGI 314

Query: 211 NRKGPQNQVGA-GTTTGLFGSSPATSSATGLFSSSTTNSGFAYGQNKTAFGTSTTGFGTN 269
           N  G     G+     G  G    +SS+ G+  S      F  G  K   G      G+ 
Sbjct: 315 NEIGGNGMSGSVSAEAGFKGFGSDSSSSVGMLESLE----FGLGGKKVGAGFDFKYSGSR 370

Query: 270 PGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGLFGVTQASQPGG 329
             G  G +  +     ++    +   +N GF        GQ    T G     Q+S    
Sbjct: 371 KFG--GNELSENGIKVTRESSSSDLAENLGFGL---EKFGQKGFGTSGSGWNEQSSSKSD 425

Query: 330 LFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNN 368
           + G A   S    FG G    G     F   GS   G+N
Sbjct: 426 VSG-AVEKSWLFEFGLGE-TKGGAEFNFRDSGSNQSGDN 462



 Score = 32.3 bits (72), Expect = 4.3
 Identities = 40/162 (24%), Positives = 60/162 (37%), Gaps = 25/162 (15%)

Query: 4   KSFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFG---TSAFGSSNNTGGL--------- 51
           + FG    GG G  G+ S      GFG+ S  + G   +  FG      G          
Sbjct: 310 EGFGINEIGGNGMSGSVSAEAGFKGFGSDSSSSVGMLESLEFGLGGKKVGAGFDFKYSGS 369

Query: 52  --FGNSQTKPGGLFGTSSFSQPATSTSTGFG---FGTSTGTANTLFGTASTG-TSLFSSQ 105
             FG ++    G+  T   S    + + GFG   FG         FGT+ +G     SS+
Sbjct: 370 RKFGGNELSENGIKVTRESSSSDLAENLGFGLEKFGQKG------FGTSGSGWNEQSSSK 423

Query: 106 NNAFAQNKPTGFGNFGTSTSSGGL-FGTTNTTSNPFGSTSGS 146
           ++     + +    FG   + GG  F   ++ SN  G    S
Sbjct: 424 SDVSGAVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGDNGNS 465



 Score = 32.0 bits (71), Expect = 5.6
 Identities = 40/163 (24%), Positives = 59/163 (36%), Gaps = 28/163 (17%)

Query: 268 TNPGGLFGQQNQQTTS-----LFSKPFGQATTTQNTG---FSFGNTSTIGQPSTNTMGLF 319
           T PGG F   +    S     LFS  FG     ++     +  GN+ +   P+ +T   +
Sbjct: 115 TPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDEDKSRERWDAGNSRSEDSPADSTNTRY 174

Query: 320 GVTQASQPGGL---FGTATNTSTGTAFGTGTG--------------LFGQTNTGFGAVGS 362
           G   +S    L   FG   +   G       G              +FG    G G+ G 
Sbjct: 175 GAGFSSSGASLDVGFGWGISDEKGLEVSKADGRETRGSGSAGGETIVFGPDAVGTGSSGL 234

Query: 363 TLFGNNKLTTFGSSTTSAPSFGTT---SGGLFGFGTNTSGNSI 402
            L        FG   + + SFG T   S  + G  T++SG S+
Sbjct: 235 KLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSV 277


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 74,685,707
Number of Sequences: 37866
Number of extensions: 3821896
Number of successful extensions: 17421
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 85
Number of HSP's successfully gapped in prelim test: 266
Number of HSP's that attempted gapping in prelim test: 11778
Number of HSP's gapped (non-prelim): 2368
length of query: 1800
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1683
effective length of database: 13,817,196
effective search space: 23254340868
effective search space used: 23254340868
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.