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Search of human proteins with 21264326
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21264326 rhomboid protease 3 [Homo sapiens]
(404 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21264326 rhomboid protease 3 [Homo sapiens] 823 0.0
gi|4506525 rhomboid protease 1 [Homo sapiens] 441 e-124
gi|54144654 rhomboid protease 2 [Homo sapiens] 186 3e-47
gi|190341097 rhomboid family 1 [Homo sapiens] 54 2e-07
gi|93352558 rhomboid, veinlet-like 6 isoform 2 [Homo sapiens] 54 3e-07
gi|93352556 rhomboid, veinlet-like 6 isoform 1 [Homo sapiens] 54 3e-07
gi|223718250 plastin 1 [Homo sapiens] 46 5e-05
gi|223718246 plastin 1 [Homo sapiens] 46 5e-05
gi|58218968 calmodulin 3 [Homo sapiens] 45 1e-04
gi|4502549 calmodulin 2 [Homo sapiens] 45 1e-04
gi|5901912 calmodulin 1 [Homo sapiens] 45 1e-04
gi|4885111 calmodulin-like 3 [Homo sapiens] 43 6e-04
gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial... 42 0.001
gi|133908614 glycerol-3-phosphate dehydrogenase 2, mitochondrial... 42 0.001
gi|32698884 calcium binding protein 7 [Homo sapiens] 40 0.005
gi|10864037 myosin light chain 2a [Homo sapiens] 37 0.042
gi|4507615 troponin C, slow [Homo sapiens] 36 0.071
gi|7019485 programmed cell death 6 [Homo sapiens] 36 0.071
gi|50897266 calmodulin-like 6 [Homo sapiens] 35 0.12
gi|110611180 calcium binding protein 2 isoform 2 [Homo sapiens] 35 0.12
gi|110611178 calcium binding protein 2 isoform 1 [Homo sapiens] 35 0.12
gi|112799847 cardiac muscle ryanodine receptor [Homo sapiens] 35 0.16
gi|226371754 katanin p60 subunit A-like 2 [Homo sapiens] 34 0.21
gi|223278387 calmodulin-like 5 [Homo sapiens] 34 0.21
gi|156616292 EF-hand domain (C-terminal) containing 1 [Homo sapi... 34 0.21
gi|194097352 actinin, alpha 1 isoform c [Homo sapiens] 33 0.35
gi|154759259 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) ... 33 0.46
gi|194595509 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) ... 33 0.46
gi|38570109 CAP-binding protein complex interacting protein 1 is... 33 0.46
gi|38570107 CAP-binding protein complex interacting protein 1 is... 33 0.46
>gi|21264326 rhomboid protease 3 [Homo sapiens]
Length = 404
Score = 823 bits (2127), Expect = 0.0
Identities = 404/404 (100%), Positives = 404/404 (100%)
Query: 1 MGEHPSPGPAVAACAEAERIEELEPEAEERLPAAPEDHWKVLFDQFDPGNTGYISTGKFR 60
MGEHPSPGPAVAACAEAERIEELEPEAEERLPAAPEDHWKVLFDQFDPGNTGYISTGKFR
Sbjct: 1 MGEHPSPGPAVAACAEAERIEELEPEAEERLPAAPEDHWKVLFDQFDPGNTGYISTGKFR 60
Query: 61 SLLESHSSKLDPHKREVLLALADSHADGQIGYQDFVSLMSNKRSNSFRQAILQGNRRLSS 120
SLLESHSSKLDPHKREVLLALADSHADGQIGYQDFVSLMSNKRSNSFRQAILQGNRRLSS
Sbjct: 61 SLLESHSSKLDPHKREVLLALADSHADGQIGYQDFVSLMSNKRSNSFRQAILQGNRRLSS 120
Query: 121 KALLEEKGLSLSQRLIRHVAYETLPREIDRKWYYDSYTCCPPPWFMITVTLLEVAFFLYN 180
KALLEEKGLSLSQRLIRHVAYETLPREIDRKWYYDSYTCCPPPWFMITVTLLEVAFFLYN
Sbjct: 121 KALLEEKGLSLSQRLIRHVAYETLPREIDRKWYYDSYTCCPPPWFMITVTLLEVAFFLYN 180
Query: 181 GVSLGQFVLQVTHPRYLKNSLVYHPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQLLVGVP 240
GVSLGQFVLQVTHPRYLKNSLVYHPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQLLVGVP
Sbjct: 181 GVSLGQFVLQVTHPRYLKNSLVYHPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQLLVGVP 240
Query: 241 LEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMK 300
LEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMK
Sbjct: 241 LEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMK 300
Query: 301 CQFKLLRMAVALICMSMEFGRAVWLRFHPSAYPPCPHPSFVAHLGGVAVGITLGVVVLRN 360
CQFKLLRMAVALICMSMEFGRAVWLRFHPSAYPPCPHPSFVAHLGGVAVGITLGVVVLRN
Sbjct: 301 CQFKLLRMAVALICMSMEFGRAVWLRFHPSAYPPCPHPSFVAHLGGVAVGITLGVVVLRN 360
Query: 361 YEQRLQDQSLWWIFVAMYTVFVLFAVFWNIFAYTLLDLKLPPPP 404
YEQRLQDQSLWWIFVAMYTVFVLFAVFWNIFAYTLLDLKLPPPP
Sbjct: 361 YEQRLQDQSLWWIFVAMYTVFVLFAVFWNIFAYTLLDLKLPPPP 404
>gi|4506525 rhomboid protease 1 [Homo sapiens]
Length = 438
Score = 441 bits (1135), Expect = e-124
Identities = 205/360 (56%), Positives = 265/360 (73%)
Query: 45 QFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDFVSLMSNKRS 104
Q DP NTG+I F L+ SH LDP K ++L+ALA S+ GQ+ YQ+ V L+S+KRS
Sbjct: 79 QLDPENTGFIGADTFTGLVHSHELPLDPAKLDMLVALAQSNEQGQVCYQELVDLISSKRS 138
Query: 105 NSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETLPREIDRKWYYDSYTCCPPPW 164
+SF++AI G R L L+E GL + +R +R+VAYE LP E+DR+WY+ + CPPP
Sbjct: 139 SSFKRAIANGQRALPRDGPLDEPGLGVYKRFVRYVAYEILPCEVDRRWYFYRHRSCPPPV 198
Query: 165 FMITVTLLEVAFFLYNGVSLGQFVLQVTHPRYLKNSLVYHPQLRAQVWRYLTYIFMHAGI 224
FM +VTL ++ FL G L ++VLQ HP Y+K+ LVYHP RA+ WR+LTY+FMH G+
Sbjct: 199 FMASVTLAQIIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPGHRARAWRFLTYMFMHVGL 258
Query: 225 EHLGLNVVLQLLVGVPLEMVHGATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYAL 284
E LG N +LQL++GVPLEMVHG RI L+Y+AGV+AGSL VS+ DM APVVG SGGVYAL
Sbjct: 259 EQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYAL 318
Query: 285 VSAHLANIVMNWSGMKCQFKLLRMAVALICMSMEFGRAVWLRFHPSAYPPCPHPSFVAHL 344
SAHLAN+VMNW+GM+C +KLLRM +AL+CMS E GRAVWLRF P P PSF+AHL
Sbjct: 319 CSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLRFSPPLPASGPQPSFMAHL 378
Query: 345 GGVAVGITLGVVVLRNYEQRLQDQSLWWIFVAMYTVFVLFAVFWNIFAYTLLDLKLPPPP 404
G VG+++G+ +LR+YE+RL+DQ WW+ + Y F+LFAVFWN+FAY LL +PPPP
Sbjct: 379 AGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAVFWNVFAYDLLGAHIPPPP 438
>gi|54144654 rhomboid protease 2 [Homo sapiens]
Length = 303
Score = 186 bits (472), Expect = 3e-47
Identities = 100/266 (37%), Positives = 162/266 (60%), Gaps = 5/266 (1%)
Query: 127 KGLSLSQRLIRHVAYETLPREIDRKWYYDSYTCCPPPWFMITVTLLEVAFFLYNGVSLGQ 186
K + S+++ R V+ LP E R Y + C PPP F+I+++L E+A F+Y V Q
Sbjct: 37 KDRAKSKKVHRIVSKWMLP-EKSRGTYLERANCFPPPVFIISISLAELAVFIYYAVWKPQ 95
Query: 187 FVLQVTHPRYLKNSLVYHPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQLLVGVPLEMVHG 246
L++ +Y P+ R + WR+++Y+ +HAG++H+ N+ +QL++G+PLEMVH
Sbjct: 96 KQWITLDTGILESPFIYSPEKREEAWRFISYMLVHAGVQHILGNLCMQLVLGIPLEMVHK 155
Query: 247 ATRIGLVYVAGVVAGSLAVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLL 306
R+GLVY+AGV+AGSLA S+ D +VG+SGGVYAL+ + N+++N+ M F +
Sbjct: 156 GLRVGLVYLAGVIAGSLASSIFDPLRYLVGASGGVYALMGGYFMNVLVNFQEMIPAFGIF 215
Query: 307 RMAVALICMSMEFGRAVWLRFH-PSAYPPCPHPSFVAHLGGVAVGITLGVVVLRNYEQRL 365
R+ + ++ + ++ G A++ RF P P SF AH+ G G+++G V +++ L
Sbjct: 216 RLLIIILIIVLDMGFALYRRFFVPEDGSPV---SFAAHIAGGFAGMSIGYTVFSCFDKAL 272
Query: 366 QDQSLWWIFVAMYTVFVLFAVFWNIF 391
+WI +A Y VLFAVF+NIF
Sbjct: 273 LKDPRFWIAIAAYLACVLFAVFFNIF 298
>gi|190341097 rhomboid family 1 [Homo sapiens]
Length = 855
Score = 54.3 bits (129), Expect = 2e-07
Identities = 29/122 (23%), Positives = 60/122 (49%)
Query: 204 HPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQLLVGVPLEMVHGATRIGLVYVAGVVAGSL 263
+P++ Q +R +F+HAGI H +++ Q+ V LE + G RI ++Y+ V G+L
Sbjct: 646 NPEVPDQFYRLWLSLFLHAGILHCLVSICFQMTVLRDLEKLAGWHRIAIIYLLSGVTGNL 705
Query: 264 AVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLLRMAVALICMSMEFGRAV 323
A ++ VG +G + +++ + +W + ++ +A++ FG
Sbjct: 706 ASAIFLPYRAEVGPAGSQFGILACLFVELFQSWQILARPWRAFFKLLAVVLFLFTFGLLP 765
Query: 324 WL 325
W+
Sbjct: 766 WI 767
>gi|93352558 rhomboid, veinlet-like 6 isoform 2 [Homo sapiens]
Length = 827
Score = 53.5 bits (127), Expect = 3e-07
Identities = 34/155 (21%), Positives = 69/155 (44%), Gaps = 13/155 (8%)
Query: 204 HPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQLLVGVPLEMVHGATRIGLVYVAGVVAGSL 263
+P++ Q +R +F+HAG+ H ++VV Q+ + LE + G RI ++++ + G+L
Sbjct: 618 NPEVPDQFYRLWLSLFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGITGNL 677
Query: 264 AVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLLRMAVALICMSMEFGRAV 323
A ++ VG +G + L++ + +W ++ +K A++ G
Sbjct: 678 ASAIFLPYRAEVGPAGSQFGLLACLFVELFQSWPLLERPWKAFLNLSAIVLFLFICGLLP 737
Query: 324 WLRFHPSAYPPCPHPSFVAHLGGVAVGITLGVVVL 358
W+ +AH+ G G+ L L
Sbjct: 738 WI-------------DNIAHIFGFLSGLLLAFAFL 759
>gi|93352556 rhomboid, veinlet-like 6 isoform 1 [Homo sapiens]
Length = 856
Score = 53.5 bits (127), Expect = 3e-07
Identities = 34/155 (21%), Positives = 69/155 (44%), Gaps = 13/155 (8%)
Query: 204 HPQLRAQVWRYLTYIFMHAGIEHLGLNVVLQLLVGVPLEMVHGATRIGLVYVAGVVAGSL 263
+P++ Q +R +F+HAG+ H ++VV Q+ + LE + G RI ++++ + G+L
Sbjct: 647 NPEVPDQFYRLWLSLFLHAGVVHCLVSVVFQMTILRDLEKLAGWHRIAIIFILSGITGNL 706
Query: 264 AVSVADMTAPVVGSSGGVYALVSAHLANIVMNWSGMKCQFKLLRMAVALICMSMEFGRAV 323
A ++ VG +G + L++ + +W ++ +K A++ G
Sbjct: 707 ASAIFLPYRAEVGPAGSQFGLLACLFVELFQSWPLLERPWKAFLNLSAIVLFLFICGLLP 766
Query: 324 WLRFHPSAYPPCPHPSFVAHLGGVAVGITLGVVVL 358
W+ +AH+ G G+ L L
Sbjct: 767 WI-------------DNIAHIFGFLSGLLLAFAFL 788
>gi|223718250 plastin 1 [Homo sapiens]
Length = 629
Score = 46.2 bits (108), Expect = 5e-05
Identities = 29/77 (37%), Positives = 48/77 (62%), Gaps = 8/77 (10%)
Query: 43 FDQFDPGNTGYISTGKFRSLLESHSSKLDPHK-REV---LLALADSHADGQIGYQDFVSL 98
F++ D N+GY+S + + L + S L +K RE+ +L++ADS+ DG+I +++FVSL
Sbjct: 20 FNKIDIDNSGYVSDYELQDLFKEASLPLPGYKVREIVEKILSVADSNKDGKISFEEFVSL 79
Query: 99 M----SNKRSNSFRQAI 111
M S S +FR+ I
Sbjct: 80 MQELKSKDISKTFRKII 96
>gi|223718246 plastin 1 [Homo sapiens]
Length = 629
Score = 46.2 bits (108), Expect = 5e-05
Identities = 29/77 (37%), Positives = 48/77 (62%), Gaps = 8/77 (10%)
Query: 43 FDQFDPGNTGYISTGKFRSLLESHSSKLDPHK-REV---LLALADSHADGQIGYQDFVSL 98
F++ D N+GY+S + + L + S L +K RE+ +L++ADS+ DG+I +++FVSL
Sbjct: 20 FNKIDIDNSGYVSDYELQDLFKEASLPLPGYKVREIVEKILSVADSNKDGKISFEEFVSL 79
Query: 99 M----SNKRSNSFRQAI 111
M S S +FR+ I
Sbjct: 80 MQELKSKDISKTFRKII 96
>gi|58218968 calmodulin 3 [Homo sapiens]
Length = 149
Score = 45.1 bits (105), Expect = 1e-04
Identities = 21/67 (31%), Positives = 36/67 (53%)
Query: 36 EDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDF 95
E+ + F FD GYIS + R ++ + KL + + ++ AD DGQ+ Y++F
Sbjct: 83 EEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEF 142
Query: 96 VSLMSNK 102
V +M+ K
Sbjct: 143 VQMMTAK 149
>gi|4502549 calmodulin 2 [Homo sapiens]
Length = 149
Score = 45.1 bits (105), Expect = 1e-04
Identities = 21/67 (31%), Positives = 36/67 (53%)
Query: 36 EDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDF 95
E+ + F FD GYIS + R ++ + KL + + ++ AD DGQ+ Y++F
Sbjct: 83 EEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEF 142
Query: 96 VSLMSNK 102
V +M+ K
Sbjct: 143 VQMMTAK 149
>gi|5901912 calmodulin 1 [Homo sapiens]
Length = 149
Score = 45.1 bits (105), Expect = 1e-04
Identities = 21/67 (31%), Positives = 36/67 (53%)
Query: 36 EDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDF 95
E+ + F FD GYIS + R ++ + KL + + ++ AD DGQ+ Y++F
Sbjct: 83 EEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEF 142
Query: 96 VSLMSNK 102
V +M+ K
Sbjct: 143 VQMMTAK 149
>gi|4885111 calmodulin-like 3 [Homo sapiens]
Length = 149
Score = 42.7 bits (99), Expect = 6e-04
Identities = 18/67 (26%), Positives = 36/67 (53%)
Query: 36 EDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDF 95
E+ + F FD G++S + R ++ KL + + ++ AD+ DGQ+ Y++F
Sbjct: 83 EEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDEEVDEMIRAADTDGDGQVNYEEF 142
Query: 96 VSLMSNK 102
V ++ +K
Sbjct: 143 VRVLVSK 149
>gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial
[Homo sapiens]
Length = 727
Score = 42.0 bits (97), Expect = 0.001
Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 3/97 (3%)
Query: 19 RIEELEPEAEERLPAAPEDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVL 78
R E+L +E L + D +K F +FD G+I+ + +LES + ++D + +
Sbjct: 608 RSEQLTDRSEISLLPSDIDRYKKRFHKFDADQKGFITIVDVQRVLESINVQMDENTLHEI 667
Query: 79 LALADSHADGQIGYQDFVSLMS---NKRSNSFRQAIL 112
L D + +GQ+ +F+ LMS R + R AIL
Sbjct: 668 LNEVDLNKNGQVELNEFLQLMSAIQKGRVSGSRLAIL 704
>gi|133908614 glycerol-3-phosphate dehydrogenase 2, mitochondrial
[Homo sapiens]
Length = 727
Score = 42.0 bits (97), Expect = 0.001
Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 3/97 (3%)
Query: 19 RIEELEPEAEERLPAAPEDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVL 78
R E+L +E L + D +K F +FD G+I+ + +LES + ++D + +
Sbjct: 608 RSEQLTDRSEISLLPSDIDRYKKRFHKFDADQKGFITIVDVQRVLESINVQMDENTLHEI 667
Query: 79 LALADSHADGQIGYQDFVSLMS---NKRSNSFRQAIL 112
L D + +GQ+ +F+ LMS R + R AIL
Sbjct: 668 LNEVDLNKNGQVELNEFLQLMSAIQKGRVSGSRLAIL 704
>gi|32698884 calcium binding protein 7 [Homo sapiens]
Length = 215
Score = 39.7 bits (91), Expect = 0.005
Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 3/83 (3%)
Query: 27 AEERLPAAPEDHWKVL---FDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALAD 83
+E+R PED + + F FD G+IS + + + S + + EV++ D
Sbjct: 23 SEQRPVDIPEDELEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVIIQRLD 82
Query: 84 SHADGQIGYQDFVSLMSNKRSNS 106
DGQ+ +++FV+L+ K S S
Sbjct: 83 MDGDGQVDFEEFVTLLGPKLSTS 105
>gi|10864037 myosin light chain 2a [Homo sapiens]
Length = 175
Score = 36.6 bits (83), Expect = 0.042
Identities = 18/67 (26%), Positives = 32/67 (47%)
Query: 35 PEDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQD 94
PE+ F FDP G ++ +F+ LL + + K P + E + AL G I Y+
Sbjct: 103 PEEAILSAFRMFDPSGKGVVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKS 162
Query: 95 FVSLMSN 101
++++
Sbjct: 163 LCYIITH 169
>gi|4507615 troponin C, slow [Homo sapiens]
Length = 161
Score = 35.8 bits (81), Expect = 0.071
Identities = 18/64 (28%), Positives = 30/64 (46%)
Query: 36 EDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDF 95
E+ LF FD GYI + + +L++ + E L+ D + DG+I Y +F
Sbjct: 94 EEELSDLFRMFDKNADGYIDLDELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEF 153
Query: 96 VSLM 99
+ M
Sbjct: 154 LEFM 157
>gi|7019485 programmed cell death 6 [Homo sapiens]
Length = 191
Score = 35.8 bits (81), Expect = 0.071
Identities = 15/58 (25%), Positives = 27/58 (46%)
Query: 39 WKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDFV 96
W+ +F +D N+G I + + L +L ++L+ D GQI + DF+
Sbjct: 95 WQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFI 152
>gi|50897266 calmodulin-like 6 [Homo sapiens]
Length = 181
Score = 35.0 bits (79), Expect = 0.12
Identities = 18/67 (26%), Positives = 32/67 (47%)
Query: 36 EDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDF 95
E + F FD GYI + +L + L+ + E ++ AD D I Y++F
Sbjct: 109 ESELRAAFRVFDKEGKGYIDWNTLKYVLMNAGEPLNEVEAEQMMKEADKDGDRTIDYEEF 168
Query: 96 VSLMSNK 102
V++M+ +
Sbjct: 169 VAMMTGE 175
>gi|110611180 calcium binding protein 2 isoform 2 [Homo sapiens]
Length = 163
Score = 35.0 bits (79), Expect = 0.12
Identities = 18/59 (30%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
Query: 43 FDQFDPGNTGYISTGKFRSLLESH-SSKLDPHKREVLLALADSHADGQIGYQDFVSLMS 100
F +FD G IS G+ R+ L++ +L + + +L D + DG + +++FV +MS
Sbjct: 104 FREFDTNGDGRISVGELRAALKALLGERLSQREVDEILQDVDLNGDGLVDFEEFVRMMS 162
>gi|110611178 calcium binding protein 2 isoform 1 [Homo sapiens]
Length = 220
Score = 35.0 bits (79), Expect = 0.12
Identities = 18/59 (30%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
Query: 43 FDQFDPGNTGYISTGKFRSLLESH-SSKLDPHKREVLLALADSHADGQIGYQDFVSLMS 100
F +FD G IS G+ R+ L++ +L + + +L D + DG + +++FV +MS
Sbjct: 161 FREFDTNGDGRISVGELRAALKALLGERLSQREVDEILQDVDLNGDGLVDFEEFVRMMS 219
>gi|112799847 cardiac muscle ryanodine receptor [Homo sapiens]
Length = 4967
Score = 34.7 bits (78), Expect = 0.16
Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 10/120 (8%)
Query: 43 FDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDFVSLMSNK 102
F ++DP G IS F +ESH + E LL+ A++ + + Y++FV
Sbjct: 4032 FKEYDPDGKGVISKRDFHKAMESH-KHYTQSETEFLLSCAETDENETLDYEEFVKRFHEP 4090
Query: 103 RSN-SFRQAILQGN--------RRLSSKALLEEKGLSLSQRLIRHVAYETLPREIDRKWY 153
+ F A+L N RL + L E L+ Q + + + I+R ++
Sbjct: 4091 AKDIGFNVAVLLTNLSEHMPNDTRLQTFLELAESVLNYFQPFLGRIEIMGSAKRIERVYF 4150
>gi|226371754 katanin p60 subunit A-like 2 [Homo sapiens]
Length = 466
Score = 34.3 bits (77), Expect = 0.21
Identities = 23/73 (31%), Positives = 40/73 (54%), Gaps = 2/73 (2%)
Query: 77 VLLALADSHADGQIGYQDFVSLMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLI 136
VL LA HA I + S+MS + + S + +G+ R+ ++ L++ GL+ S+ L+
Sbjct: 265 VLFELARYHAPSTIFLDELESVMSQRGTASGGEH--EGSLRMKTELLVQMDGLARSEDLV 322
Query: 137 RHVAYETLPREID 149
+A LP E+D
Sbjct: 323 FVLAASNLPWELD 335
>gi|223278387 calmodulin-like 5 [Homo sapiens]
Length = 146
Score = 34.3 bits (77), Expect = 0.21
Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 8/83 (9%)
Query: 22 ELEPEAEERLPAAPEDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLAL 81
EL PE E + +K F D G I+ + + L++ L + L++
Sbjct: 4 ELTPEEEAQ--------YKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISE 55
Query: 82 ADSHADGQIGYQDFVSLMSNKRS 104
DS DG+I +Q+F++ R+
Sbjct: 56 VDSDGDGEISFQEFLTAAKKARA 78
Score = 34.3 bits (77), Expect = 0.21
Identities = 18/76 (23%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Query: 27 AEERLPAAPEDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHA 86
A ++ A ED +V F FD G+I+ + R + L + + ++ AD
Sbjct: 72 AAKKARAGLED-LQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQ 130
Query: 87 DGQIGYQDFVSLMSNK 102
DG++ Y++F +++ +
Sbjct: 131 DGRVNYEEFARMLAQE 146
>gi|156616292 EF-hand domain (C-terminal) containing 1 [Homo
sapiens]
Length = 640
Score = 34.3 bits (77), Expect = 0.21
Identities = 19/66 (28%), Positives = 34/66 (51%), Gaps = 1/66 (1%)
Query: 36 EDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDF 95
+D+ + F +D +GY+ F + ES + +D + L+ + SH +G+I Y +F
Sbjct: 576 KDNIREAFQIYDKEASGYVDRDMFFKICESLNVPVDDSLVKELIRMC-SHGEGKINYYNF 634
Query: 96 VSLMSN 101
V SN
Sbjct: 635 VRAFSN 640
>gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]
Length = 887
Score = 33.5 bits (75), Expect = 0.35
Identities = 16/70 (22%), Positives = 36/70 (51%)
Query: 37 DHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDFV 96
+ ++ F+ FD TG + T FR+ L S + + ++++ D + G + +Q F+
Sbjct: 749 NEFRASFNHFDRKKTGMMDTDDFRACLISMGYNMGEAEFARIMSIVDPNRLGVVTFQAFI 808
Query: 97 SLMSNKRSNS 106
MS + +++
Sbjct: 809 DFMSRETADT 818
>gi|154759259 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
isoform 2 [Homo sapiens]
Length = 2472
Score = 33.1 bits (74), Expect = 0.46
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 11/112 (9%)
Query: 39 WKVLFDQFDPGNTGYISTGKFRSLLES--------HSSKLDPHKREVLLALADSHADGQI 90
+ ++F FD +G ++ +F+S L S + DP + E +L D + DG +
Sbjct: 2328 FSMMFKHFDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDP-EFEAILDTVDPNRDGHV 2386
Query: 91 GYQDFVSLMSNKRSNSFR--QAILQGNRRLSSKALLEEKGLSLSQRLIRHVA 140
Q++++ M ++ + + + + I R LSS+ L Q L R A
Sbjct: 2387 SLQEYMAFMISRETENVKSSEEIESAFRALSSEGKPYVTKEELYQNLTREQA 2438
>gi|194595509 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
isoform 1 [Homo sapiens]
Length = 2477
Score = 33.1 bits (74), Expect = 0.46
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 11/112 (9%)
Query: 39 WKVLFDQFDPGNTGYISTGKFRSLLES--------HSSKLDPHKREVLLALADSHADGQI 90
+ ++F FD +G ++ +F+S L S + DP + E +L D + DG +
Sbjct: 2333 FSMMFKHFDKDKSGRLNHQEFKSCLRSLGYDLPMVEEGEPDP-EFEAILDTVDPNRDGHV 2391
Query: 91 GYQDFVSLMSNKRSNSFR--QAILQGNRRLSSKALLEEKGLSLSQRLIRHVA 140
Q++++ M ++ + + + + I R LSS+ L Q L R A
Sbjct: 2392 SLQEYMAFMISRETENVKSSEEIESAFRALSSEGKPYVTKEELYQNLTREQA 2443
>gi|38570109 CAP-binding protein complex interacting protein 1 isoform
b [Homo sapiens]
Length = 1349
Score = 33.1 bits (74), Expect = 0.46
Identities = 16/54 (29%), Positives = 25/54 (46%)
Query: 43 FDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDFV 96
F +D TG +S FR++L +S L + +L D +I Y DF+
Sbjct: 1291 FKSYDEAGTGLLSVADFRTVLRQYSINLSEEEFFHILEYYDKTLSSKISYNDFL 1344
Score = 32.7 bits (73), Expect = 0.60
Identities = 29/105 (27%), Positives = 42/105 (40%), Gaps = 2/105 (1%)
Query: 1 MGEHPSPGPAVAACAEAERIEELEPEAEERLPAAPEDHWKVLFDQFDPGNTGYISTGKFR 60
MG P E ++ E A ++L +D K F + D T YIS K +
Sbjct: 780 MGHFTKPQQLQEEMKELQQSTEKAVAARDKLMDRHQDISKA-FTKTDQSKTNYISICKMQ 838
Query: 61 SLLESHSSKLDPHKREVLL-ALADSHADGQIGYQDFVSLMSNKRS 104
+LE L + LL + S D I Y DF+ + N +S
Sbjct: 839 EVLEECGCSLTEGELTHLLNSWGVSRHDNAINYLDFLRAVENSKS 883
Score = 28.9 bits (63), Expect = 8.7
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 9/115 (7%)
Query: 43 FDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDFVSLMSNK 102
F+ D TG + + R +LE+ KL + E + H D + Y F+ +S
Sbjct: 29 FELIDVNKTGLVRPQELRRVLETFCMKLRDEEYEKFSKHYNIHKDTAVDYNVFLKNLSIN 88
Query: 103 RSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETLPR-----EIDRKW 152
+ R + GN+ +S + ++ S +RL+ + E + R EI+R +
Sbjct: 89 NDLNLRYCM--GNQEVSLEN--QQAKNSKKERLLGSASSEDIWRNYSLDEIERNF 139
Score = 28.9 bits (63), Expect = 8.7
Identities = 11/31 (35%), Positives = 18/31 (58%)
Query: 36 EDHWKVLFDQFDPGNTGYISTGKFRSLLESH 66
+ +K L DPG+TG ++T F L+E +
Sbjct: 289 DSEFKELMQMLDPGDTGVVNTSMFIDLIEEN 319
>gi|38570107 CAP-binding protein complex interacting protein 1 isoform
a [Homo sapiens]
Length = 1501
Score = 33.1 bits (74), Expect = 0.46
Identities = 16/54 (29%), Positives = 25/54 (46%)
Query: 43 FDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDFV 96
F +D TG +S FR++L +S L + +L D +I Y DF+
Sbjct: 1443 FKSYDEAGTGLLSVADFRTVLRQYSINLSEEEFFHILEYYDKTLSSKISYNDFL 1496
Score = 32.7 bits (73), Expect = 0.60
Identities = 29/105 (27%), Positives = 42/105 (40%), Gaps = 2/105 (1%)
Query: 1 MGEHPSPGPAVAACAEAERIEELEPEAEERLPAAPEDHWKVLFDQFDPGNTGYISTGKFR 60
MG P E ++ E A ++L +D K F + D T YIS K +
Sbjct: 932 MGHFTKPQQLQEEMKELQQSTEKAVAARDKLMDRHQDISKA-FTKTDQSKTNYISICKMQ 990
Query: 61 SLLESHSSKLDPHKREVLL-ALADSHADGQIGYQDFVSLMSNKRS 104
+LE L + LL + S D I Y DF+ + N +S
Sbjct: 991 EVLEECGCSLTEGELTHLLNSWGVSRHDNAINYLDFLRAVENSKS 1035
Score = 28.9 bits (63), Expect = 8.7
Identities = 27/115 (23%), Positives = 50/115 (43%), Gaps = 9/115 (7%)
Query: 43 FDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDFVSLMSNK 102
F+ D TG + + R +LE+ KL + E + H D + Y F+ +S
Sbjct: 181 FELIDVNKTGLVRPQELRRVLETFCMKLRDEEYEKFSKHYNIHKDTAVDYNVFLKNLSIN 240
Query: 103 RSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETLPR-----EIDRKW 152
+ R + GN+ +S + ++ S +RL+ + E + R EI+R +
Sbjct: 241 NDLNLRYCM--GNQEVSLEN--QQAKNSKKERLLGSASSEDIWRNYSLDEIERNF 291
Score = 28.9 bits (63), Expect = 8.7
Identities = 11/31 (35%), Positives = 18/31 (58%)
Query: 36 EDHWKVLFDQFDPGNTGYISTGKFRSLLESH 66
+ +K L DPG+TG ++T F L+E +
Sbjct: 441 DSEFKELMQMLDPGDTGVVNTSMFIDLIEEN 471
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.138 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,440,231
Number of Sequences: 37866
Number of extensions: 700503
Number of successful extensions: 2696
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 2639
Number of HSP's gapped (non-prelim): 85
length of query: 404
length of database: 18,247,518
effective HSP length: 105
effective length of query: 299
effective length of database: 14,271,588
effective search space: 4267204812
effective search space used: 4267204812
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.