Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 212276070
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|212276070 leucine rich repeat (in FLII) interacting protein
1 isoform 4 [Homo sapiens]
(784 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|212276070 leucine rich repeat (in FLII) interacting protein 1... 1549 0.0
gi|212276096 leucine rich repeat (in FLII) interacting protein 1... 1535 0.0
gi|212276104 leucine rich repeat (in FLII) interacting protein 1... 1472 0.0
gi|212276088 leucine rich repeat (in FLII) interacting protein 1... 447 e-125
gi|212276078 leucine rich repeat (in FLII) interacting protein 1... 271 1e-72
gi|8923224 leucine rich repeat (in FLII) interacting protein 2 i... 214 2e-55
gi|197276647 leucine rich repeat (in FLII) interacting protein 2... 203 4e-52
gi|5453726 leucine rich repeat (in FLII) interacting protein 2 i... 157 4e-38
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 79 2e-14
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 68 3e-11
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 67 8e-11
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 60 1e-08
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 58 3e-08
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 58 3e-08
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 57 7e-08
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 57 7e-08
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 57 7e-08
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 56 1e-07
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 55 3e-07
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 55 3e-07
gi|157738619 smoothelin-like 1 [Homo sapiens] 55 3e-07
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 54 4e-07
gi|150170670 piccolo isoform 2 [Homo sapiens] 54 7e-07
gi|150378539 piccolo isoform 1 [Homo sapiens] 54 7e-07
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 53 1e-06
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 53 1e-06
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 53 1e-06
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 53 1e-06
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 52 2e-06
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 52 2e-06
>gi|212276070 leucine rich repeat (in FLII) interacting protein 1
isoform 4 [Homo sapiens]
Length = 784
Score = 1549 bits (4010), Expect = 0.0
Identities = 784/784 (100%), Positives = 784/784 (100%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR 60
MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR
Sbjct: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR 60
Query: 61 SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 120
SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS
Sbjct: 61 SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 120
Query: 121 GDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE 180
GDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE
Sbjct: 121 GDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE 180
Query: 181 QLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGE 240
QLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGE
Sbjct: 181 QLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGE 240
Query: 241 TSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKE 300
TSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKE
Sbjct: 241 TSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKE 300
Query: 301 QHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPEN 360
QHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPEN
Sbjct: 301 QHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPEN 360
Query: 361 TVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLG 420
TVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLG
Sbjct: 361 TVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLG 420
Query: 421 HSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGE 480
HSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGE
Sbjct: 421 HSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGE 480
Query: 481 ETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDS 540
ETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDS
Sbjct: 481 ETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDS 540
Query: 541 SQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQN 600
SQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQN
Sbjct: 541 SQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQN 600
Query: 601 EVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTV 660
EVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTV
Sbjct: 601 EVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTV 660
Query: 661 QSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEA 720
QSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEA
Sbjct: 661 QSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEA 720
Query: 721 ESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGNEKGKSKED 780
ESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGNEKGKSKED
Sbjct: 721 ESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGNEKGKSKED 780
Query: 781 CTMS 784
CTMS
Sbjct: 781 CTMS 784
>gi|212276096 leucine rich repeat (in FLII) interacting protein 1
isoform 3 [Homo sapiens]
Length = 808
Score = 1535 bits (3975), Expect = 0.0
Identities = 784/808 (97%), Positives = 784/808 (97%), Gaps = 24/808 (2%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR 60
MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR
Sbjct: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR 60
Query: 61 SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 120
SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS
Sbjct: 61 SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 120
Query: 121 GDTSISIDTEASIREIK------------------------DSLAEVEEKYKKAMVSNAQ 156
GDTSISIDTEASIREIK DSLAEVEEKYKKAMVSNAQ
Sbjct: 121 GDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQ 180
Query: 157 LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA 216
LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA
Sbjct: 181 LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA 240
Query: 217 LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRAS 276
LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRAS
Sbjct: 241 LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRAS 300
Query: 277 EVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLG 336
EVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLG
Sbjct: 301 EVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLG 360
Query: 337 TLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHT 396
TLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHT
Sbjct: 361 TLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHT 420
Query: 397 ENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQE 456
ENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQE
Sbjct: 421 ENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQE 480
Query: 457 AAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDT 516
AAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDT
Sbjct: 481 AAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDT 540
Query: 517 QNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNT 576
QNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNT
Sbjct: 541 QNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNT 600
Query: 577 DLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEG 636
DLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEG
Sbjct: 601 DLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEG 660
Query: 637 DDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKS 696
DDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKS
Sbjct: 661 DDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKS 720
Query: 697 EDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGRE 756
EDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGRE
Sbjct: 721 EDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGRE 780
Query: 757 PGHFNPESREDTRGGNEKGKSKEDCTMS 784
PGHFNPESREDTRGGNEKGKSKEDCTMS
Sbjct: 781 PGHFNPESREDTRGGNEKGKSKEDCTMS 808
>gi|212276104 leucine rich repeat (in FLII) interacting protein 1
isoform 5 [Homo sapiens]
Length = 752
Score = 1472 bits (3810), Expect = 0.0
Identities = 752/784 (95%), Positives = 752/784 (95%), Gaps = 32/784 (4%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR 60
MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE
Sbjct: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE--------- 51
Query: 61 SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 120
VEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS
Sbjct: 52 -----------------------VEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 88
Query: 121 GDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE 180
GDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE
Sbjct: 89 GDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE 148
Query: 181 QLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGE 240
QLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGE
Sbjct: 149 QLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGE 208
Query: 241 TSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKE 300
TSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKE
Sbjct: 209 TSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKE 268
Query: 301 QHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPEN 360
QHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPEN
Sbjct: 269 QHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPEN 328
Query: 361 TVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLG 420
TVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLG
Sbjct: 329 TVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLG 388
Query: 421 HSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGE 480
HSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGE
Sbjct: 389 HSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGE 448
Query: 481 ETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDS 540
ETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDS
Sbjct: 449 ETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDS 508
Query: 541 SQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQN 600
SQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQN
Sbjct: 509 SQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQN 568
Query: 601 EVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTV 660
EVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTV
Sbjct: 569 EVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTV 628
Query: 661 QSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEA 720
QSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEA
Sbjct: 629 QSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEA 688
Query: 721 ESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGNEKGKSKED 780
ESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGNEKGKSKED
Sbjct: 689 ESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGNEKGKSKED 748
Query: 781 CTMS 784
CTMS
Sbjct: 749 CTMS 752
>gi|212276088 leucine rich repeat (in FLII) interacting protein 1
isoform 2 [Homo sapiens]
Length = 394
Score = 447 bits (1149), Expect = e-125
Identities = 256/377 (67%), Positives = 276/377 (73%), Gaps = 44/377 (11%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR 60
MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE
Sbjct: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE--------- 51
Query: 61 SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 120
VEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS
Sbjct: 52 -----------------------VEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS 88
Query: 121 GDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE 180
GDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE
Sbjct: 89 GDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE 148
Query: 181 QLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGE 240
QLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGE
Sbjct: 149 QLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGE 208
Query: 241 TSDTLNNVGYQGPTKMTKEELNALKSTGDGTLG---------RASEVEVKNEIVANVGKR 291
TSDTLNNVGYQGPTKMTKEELNALKSTGDGTL R +E ++ + +R
Sbjct: 209 TSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEER 268
Query: 292 EILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQV---Q 348
+ + + + +D +++ D+ V + Q S E+ V +
Sbjct: 269 QKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLE 328
Query: 349 SQILESSSLPENTVQVE 365
SQ+ S EN ++E
Sbjct: 329 SQVSRYKSAAENAEKIE 345
Score = 33.5 bits (75), Expect = 0.78
Identities = 38/159 (23%), Positives = 66/159 (41%), Gaps = 10/159 (6%)
Query: 437 PQELETSTGHSLEKEFTNQEAAE--PKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEV 494
P+ + + K EA E KE+ EV + E++ E G R+ +
Sbjct: 17 PEAQKLAEARLAAKRAARAEAREIRMKELERQQKEV-EERPEKDFTEKGSRNMPGLSAAT 75
Query: 495 PGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKK 554
S GT ++DT+ ++K+ E ++ +A+ S N + N+K
Sbjct: 76 LASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVS------NAQLDNEK 129
Query: 555 KKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRK 593
V+TLKD+ EL Q + S + EE+ K +R+
Sbjct: 130 TNFMYQVDTLKDMLLELEEQLAE-SRRQYEEKNKEFERE 167
>gi|212276078 leucine rich repeat (in FLII) interacting protein 1
isoform 1 [Homo sapiens]
Length = 640
Score = 271 bits (694), Expect = 1e-72
Identities = 171/293 (58%), Positives = 193/293 (65%), Gaps = 37/293 (12%)
Query: 47 RQQKEEDSERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAA 106
R+ S S S S+S R S +R S VEERPEKDFTEKGSRNMPGLSAA
Sbjct: 176 RRGSTSGSRAPSEYSGHLNSSSRASSRAS-SARASPVVEERPEKDFTEKGSRNMPGLSAA 234
Query: 107 TLASLGGTSSRRGSGDTSISIDTEASIREIK------------------------DSLAE 142
TLASLGGTSSRRGSGDTSISIDTEASIREIK DSLAE
Sbjct: 235 TLASLGGTSSRRGSGDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAE 294
Query: 143 VEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHA 202
VEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHA
Sbjct: 295 VEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHA 354
Query: 203 HSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQ----GPTKMTK 258
HSILQFQFAEVKEALKQREEMLE+ + + ++ E SD + ++ G + K
Sbjct: 355 HSILQFQFAEVKEALKQREEMLEEIRQLQQKQASSIREISDLQETIEWKDKKIGALERQK 414
Query: 259 EELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTE--KEQHTEDTVKD 309
E ++++S D R V +K E+ K I+ N+E T DT+ +
Sbjct: 415 EFFDSVRSERDDL--REEVVMLKEEL----KKHGIILNSEIATNGETSDTLNN 461
Score = 105 bits (261), Expect = 2e-22
Identities = 65/95 (68%), Positives = 68/95 (71%), Gaps = 23/95 (24%)
Query: 11 EIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE------------------- 51
E D L+ A++ AEARLAAKRAARAEAREIRMKELERQQKE
Sbjct: 22 EDDALNQIARE-AEARLAAKRAARAEAREIRMKELERQQKEIYQVQKKYYGLDTKWGDIE 80
Query: 52 ---EDSERYSRRSRRNTSASDEDERMSVGSRGSLR 83
EDSERYSRRSRRNTSASDEDERMSVGSRGSLR
Sbjct: 81 QWMEDSERYSRRSRRNTSASDEDERMSVGSRGSLR 115
Score = 34.3 bits (77), Expect = 0.46
Identities = 33/154 (21%), Positives = 63/154 (40%), Gaps = 4/154 (2%)
Query: 458 AEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQ 517
A + A ++ V + E++ E G R+ + S GT ++DT+
Sbjct: 199 ASSRASSARASPVVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTE 258
Query: 518 NEPLDMKEPDEEK---SDQQGEALDS-SQKKTKNKKKKNKKKKSPVPVETLKDVKKELTY 573
++KE +E K D +G+ + + K + + K KK+ V L + K Y
Sbjct: 259 ASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMY 318
Query: 574 QNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPK 607
Q L ++ E + + + + E +N+ E K
Sbjct: 319 QVDTLKDMLLELEEQLAESRRQYEEKNKEFEREK 352
>gi|8923224 leucine rich repeat (in FLII) interacting protein 2
isoform 2 [Homo sapiens]
Length = 400
Score = 214 bits (546), Expect = 2e-55
Identities = 146/370 (39%), Positives = 214/370 (57%), Gaps = 49/370 (13%)
Query: 9 SREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRNTSAS 68
S E + LS A++ AEARLAAKRAARAEAR+IRM+ELERQQKE D
Sbjct: 18 SAEDEALSNIARE-AEARLAAKRAARAEARDIRMRELERQQKELD--------------- 61
Query: 69 DEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISID 128
E+ +K + E +R SA+ L G SSRRGSGDTS ID
Sbjct: 62 -----------------EKSDKQYAENYTRPSSRNSASATTPLSGNSSRRGSGDTSSLID 104
Query: 129 TEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQ 188
+ S+ E+++SL+EVEEKYKKAMVSNAQLDNEK N +YQVDTLKD++ E EEQ+AE R+
Sbjct: 105 PDTSLSELRESLSEVEEKYKKAMVSNAQLDNEKNNLIYQVDTLKDVIEEQEEQMAEFYRE 164
Query: 189 YEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNV 248
EEK+KE ER+KH S+LQ + E+KE L+QR+E++EKHG+++ + NG+ S +
Sbjct: 165 NEEKSKELERQKHMCSVLQHKMEELKEGLRQRDELIEKHGLVIIPDGTPNGDVS---HEP 221
Query: 249 GYQGPTKMTKEELNALKSTGDGTLG-RASEVE-VKNEIVANVGKREILHNTEKEQ--HTE 304
T +++E L+S G+G L R ++ K E+++ + K ++ E+++ +
Sbjct: 222 VAGAITVVSQEAAQVLESAGEGPLDVRLRKLAGEKEELLSQIRKLKLQLEEERQKCSRND 281
Query: 305 DTVKDCVDIEVFPAGENTEDQK-SSEDTAPFLGTLAGA-----TYEEQV---QSQILESS 355
TV D ++ + E Q+ ++ + + L+ A T E+ + + Q+L
Sbjct: 282 GTVGDLAGLQNGSDLQFIEMQRDANRQISEYKFKLSKAEQDITTLEQSISRLEGQVLRYK 341
Query: 356 SLPENTVQVE 365
+ EN +VE
Sbjct: 342 TAAENAEKVE 351
Score = 32.3 bits (72), Expect = 1.7
Identities = 42/183 (22%), Positives = 69/183 (37%), Gaps = 24/183 (13%)
Query: 486 DEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQN----EPLDMKEPDEEKSDQQGEALDSS 541
DEK K + N AT P + ++ + + +PD S+ + E+L
Sbjct: 61 DEKSDKQYAENYTRPSSRNSASATTPLSGNSSRRGSGDTSSLIDPDTSLSELR-ESLSEV 119
Query: 542 QKKTK-----NKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEE----------- 585
++K K N + N+K V+TLKDV +E Q + EE+
Sbjct: 120 EEKYKKAMVSNAQLDNEKNNLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKELERQKHMC 179
Query: 586 ---QVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTA 642
Q K + K + ++E+ E I + + N D P + QE V +
Sbjct: 180 SVLQHKMEELKEGLRQRDELIEKHGLVIIPDGTPNGDVSHEPVAGAITVVSQEAAQVLES 239
Query: 643 AEE 645
A E
Sbjct: 240 AGE 242
>gi|197276647 leucine rich repeat (in FLII) interacting protein 2
isoform 3 [Homo sapiens]
Length = 424
Score = 203 bits (517), Expect = 4e-52
Identities = 147/394 (37%), Positives = 215/394 (54%), Gaps = 73/394 (18%)
Query: 9 SREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRNTSAS 68
S E + LS A++ AEARLAAKRAARAEAR+IRM+ELERQQKE D
Sbjct: 18 SAEDEALSNIARE-AEARLAAKRAARAEARDIRMRELERQQKELD--------------- 61
Query: 69 DEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISID 128
E+ +K + E +R SA+ L G SSRRGSGDTS ID
Sbjct: 62 -----------------EKSDKQYAENYTRPSSRNSASATTPLSGNSSRRGSGDTSSLID 104
Query: 129 TEASI------------------------REIKDSLAEVEEKYKKAMVSNAQLDNEKTNF 164
+ S+ +E+K+SL+EVEEKYKKAMVSNAQLDNEK N
Sbjct: 105 PDTSLSELRDIYDLKDQIQDVEGRYMQGLKELKESLSEVEEKYKKAMVSNAQLDNEKNNL 164
Query: 165 MYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEML 224
+YQVDTLKD++ E EEQ+AE R+ EEK+KE ER+KH S+LQ + E+KE L+QR+E++
Sbjct: 165 IYQVDTLKDVIEEQEEQMAEFYRENEEKSKELERQKHMCSVLQHKMEELKEGLRQRDELI 224
Query: 225 EKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLG-RASEVE-VKN 282
EKHG+++ + NG+ S + T +++E L+S G+G L R ++ K
Sbjct: 225 EKHGLVIIPDGTPNGDVS---HEPVAGAITVVSQEAAQVLESAGEGPLDVRLRKLAGEKE 281
Query: 283 EIVANVGKREILHNTEKEQ--HTEDTVKDCVDIEVFPAGENTEDQK-SSEDTAPFLGTLA 339
E+++ + K ++ E+++ + TV D ++ + E Q+ ++ + + L+
Sbjct: 282 ELLSQIRKLKLQLEEERQKCSRNDGTVGDLAGLQNGSDLQFIEMQRDANRQISEYKFKLS 341
Query: 340 GA-----TYEEQV---QSQILESSSLPENTVQVE 365
A T E+ + + Q+L + EN +VE
Sbjct: 342 KAEQDITTLEQSISRLEGQVLRYKTAAENAEKVE 375
>gi|5453726 leucine rich repeat (in FLII) interacting protein 2
isoform 1 [Homo sapiens]
Length = 721
Score = 157 bits (397), Expect = 4e-38
Identities = 91/204 (44%), Positives = 128/204 (62%), Gaps = 27/204 (13%)
Query: 47 RQQKEEDSERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAA 106
R+ ++ +SR +RR + S+ D+ +S+ SL +E+ +K + E +R SA+
Sbjct: 258 RESVVSAADYFSRSNRRGSVVSEVDD-ISIPDLSSL--DEKSDKQYAENYTRPSSRNSAS 314
Query: 107 TLASLGGTSSRRGSGDTSISIDTEASI------------------------REIKDSLAE 142
L G SSRRGSGDTS ID + S+ +E+K+SL+E
Sbjct: 315 ATTPLSGNSSRRGSGDTSSLIDPDTSLSELRDIYDLKDQIQDVEGRYMQGLKELKESLSE 374
Query: 143 VEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHA 202
VEEKYKKAMVSNAQLDNEK N +YQVDTLKD++ E EEQ+AE R+ EEK+KE ER+KH
Sbjct: 375 VEEKYKKAMVSNAQLDNEKNNLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKELERQKHM 434
Query: 203 HSILQFQFAEVKEALKQREEMLEK 226
S+LQ + E+KE L+QR+E++E+
Sbjct: 435 CSVLQHKMEELKEGLRQRDELIEE 458
Score = 62.8 bits (151), Expect = 1e-09
Identities = 46/96 (47%), Positives = 57/96 (59%), Gaps = 20/96 (20%)
Query: 9 SREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKE----------------- 51
S E + LS A++ AEARLAAKRAARAEAR+IRM+ELERQQKE
Sbjct: 18 SAEDEALSNIARE-AEARLAAKRAARAEARDIRMRELERQQKEYSLHSFDRKWGQIQKWL 76
Query: 52 EDSE--RYSRRSRRNTSASDEDERMSVGSRGSLRVE 85
EDSE RYS RS + ++ +S+ S GS R +
Sbjct: 77 EDSERARYSHRSSHHRPYLGVEDALSIRSVGSHRYD 112
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 78.6 bits (192), Expect = 2e-14
Identities = 142/692 (20%), Positives = 268/692 (38%), Gaps = 110/692 (15%)
Query: 128 DTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRR 187
DTEA+IR ++ + E A + +LD + + +V L+ EE++A+
Sbjct: 198 DTEAAIRALRKDIEE-------ASLVKVELDKKVQSLQDEVAFLRS---NHEEEVADLLA 247
Query: 188 QYEEKNKEFEREKHAHSILQFQFAEVKEALK--------QREEMLEKHGIILNSEIATNG 239
Q + + ER+ + + + E++ L+ Q EE + L N
Sbjct: 248 QIQASHITVERKDYLKTDISTALKEIRSQLESHSDQNMHQAEEWFKCRYAKLTEAAEQNK 307
Query: 240 ETSDTLNN--VGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKN--EIVANVGKREILH 295
E + Y+ + EL +++ T + + S++E ++ ++ + + L
Sbjct: 308 EAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLE 367
Query: 296 NT------EKEQHTED-----TVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATY- 343
N E +H + VK +DIE+ + E +++ T F G++ G Y
Sbjct: 368 NELRGTKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFST--FAGSITGPLYT 425
Query: 344 -------EEQVQSQILESSSLP-----------ENTVQVESNEVMGAPDDRTRTPLEPSN 385
++Q +E+ L E V+ E +E+ A T L S
Sbjct: 426 HRPPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEE-LAVSM 484
Query: 386 CWSDLDGGNHTENVGEAAVTQVEEQAGTV-ASCPLGHSDDTVYHDDKCMVEVPQELETST 444
+ E EA +V + V A+ P ++ +++ E +E E +
Sbjct: 485 KEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAK 544
Query: 445 GHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPI-------------- 490
E+ + +E + KE E G E EGEE ++EK +
Sbjct: 545 SDQAEEGGSEKEGSSEKE--EGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELV 602
Query: 491 -----------KTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEK--SDQQGEA 537
K+ VP SP +G P V+ + + K P EEK S
Sbjct: 603 ADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSP--VEEKGKSPVPKSPVEEKGKSPVPKSP 660
Query: 538 LDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVE 597
++ K +K +K KSPVP +++ K + + E +EE++VK ++ VE
Sbjct: 661 VEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKE-EEEKEVKEAPKEEKVE 719
Query: 598 AQNEVTENPKQKIAAES-------SENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADG 650
+ E ++ +K AES +E V ++ K+ L+ + +EG +Q E+ A G
Sbjct: 720 KKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGG 779
Query: 651 DTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHE-- 708
+ G ++ +G K++ ++G + E + E ++ + E E
Sbjct: 780 ----------EGGSEEEGSDKGAKGSRKEDIAVNGEVEGK-EEVEQETKEKGSGREEEKG 828
Query: 709 --SPSQDISDACEAESTERCEMSEHPSQTVRK 738
+ D+S A E + ++ E ++TV K
Sbjct: 829 VVTNGLDLSPADEKKGGDKSEEKVVVTKTVEK 860
Score = 39.3 bits (90), Expect = 0.014
Identities = 58/250 (23%), Positives = 104/250 (41%), Gaps = 28/250 (11%)
Query: 541 SQKKTKNKKKKNKKKKSPVPVETLKD---VKKELTYQNTDLSEIKEEEQVK-STDRKSAV 596
S K K K + K K VE + + V+ E + L+ I EE V ++K A
Sbjct: 433 SSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAA 492
Query: 597 EAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFE 656
E + E E ++++AA+ S P++K ++EG+ + +E + D
Sbjct: 493 EEKEEEPEAEEEEVAAKKSPVK--ATAPEVK-----EEEGEKEEEEGQEEEEEEDEGAKS 545
Query: 657 DDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISD 716
D + + G E +EG + +G T+ AE + E+A+ + E S++++
Sbjct: 546 DQAEEGGSEKEGSSEKEEGEQE-----EGETE---AEAEGEEAEAKEEKKVEEKSEEVAT 597
Query: 717 ACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFN-PESREDTRGGN--- 772
E + + E E V K+ ++ +P E G P+S + +G +
Sbjct: 598 KEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVP 657
Query: 773 -----EKGKS 777
EKGKS
Sbjct: 658 KSPVEEKGKS 667
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 68.2 bits (165), Expect = 3e-11
Identities = 106/490 (21%), Positives = 191/490 (38%), Gaps = 77/490 (15%)
Query: 307 VKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATY--------EEQVQSQILESSSLP 358
VK +DIE+ + E +++ T F G++ G Y ++Q +E+ L
Sbjct: 14 VKMALDIEIAAYRKLLEGEETRFST--FAGSITGPLYTHRPPITISSKIQKPKVEAPKLK 71
Query: 359 -----------ENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQV 407
E V+ E +E+ A T L S + E EA +V
Sbjct: 72 VQHKFVEEIIEETKVEDEKSEMEEALTAITEE-LAVSMKEEKKEAAEEKEEEPEAEEEEV 130
Query: 408 EEQAGTV-ASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAH 466
+ V A+ P ++ +++ E +E E + E+ + +E + KE
Sbjct: 131 AAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKE--EG 188
Query: 467 STEVGRDHNEEEGEETGLRDEKPI-------------------------KTEVPGSPAGT 501
E G E EGEE ++EK + K+ VP SP
Sbjct: 189 EQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEE 248
Query: 502 EGNCQEATGPSTVDTQNEPLDMKEPDEEK--SDQQGEALDSSQKKTKNKKKKNKKKKSPV 559
+G P V+ + + K P EEK S ++ K +K +K KSPV
Sbjct: 249 KGKSPVPKSP--VEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPV 306
Query: 560 PVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAES----- 614
P +++ K + + E +EE++VK ++ VE + E ++ +K AES
Sbjct: 307 PKSPVEEAKSKAEVGKGEQKE-EEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEE 365
Query: 615 --SENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEEL 672
+E V ++ K+ L+ + +EG +Q E+ A G + G ++
Sbjct: 366 AVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGG----------EGGSEEEGSDKG 415
Query: 673 DEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHE----SPSQDISDACEAESTERCEM 728
+G K++ ++G + E + E ++ + E E + D+S A E + ++ E
Sbjct: 416 AKGSRKEDIAVNGEVEGK-EEVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEE 474
Query: 729 SEHPSQTVRK 738
++TV K
Sbjct: 475 KVVVTKTVEK 484
Score = 39.3 bits (90), Expect = 0.014
Identities = 58/250 (23%), Positives = 104/250 (41%), Gaps = 28/250 (11%)
Query: 541 SQKKTKNKKKKNKKKKSPVPVETLKD---VKKELTYQNTDLSEIKEEEQVK-STDRKSAV 596
S K K K + K K VE + + V+ E + L+ I EE V ++K A
Sbjct: 57 SSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAA 116
Query: 597 EAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFE 656
E + E E ++++AA+ S P++K ++EG+ + +E + D
Sbjct: 117 EEKEEEPEAEEEEVAAKKSPVK--ATAPEVK-----EEEGEKEEEEGQEEEEEEDEGAKS 169
Query: 657 DDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISD 716
D + + G E +EG + +G T+ AE + E+A+ + E S++++
Sbjct: 170 DQAEEGGSEKEGSSEKEEGEQE-----EGETE---AEAEGEEAEAKEEKKVEEKSEEVAT 221
Query: 717 ACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFN-PESREDTRGGN--- 772
E + + E E V K+ ++ +P E G P+S + +G +
Sbjct: 222 KEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVP 281
Query: 773 -----EKGKS 777
EKGKS
Sbjct: 282 KSPVEEKGKS 291
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 66.6 bits (161), Expect = 8e-11
Identities = 157/737 (21%), Positives = 270/737 (36%), Gaps = 116/737 (15%)
Query: 94 EKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTE------ASIREIKDSLAEVEEKY 147
+ G M L + + G R G+ + ++ E A +R+ D A E+
Sbjct: 136 QAGRSAMGELYEREVREMRGAVLRLGAARGQLRLEQEHLLEDIAHVRQRLDDEARQREEA 195
Query: 148 KKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQ 207
+ A + A+ E +VD L+ L+E+ RR ++E+ E + Q
Sbjct: 196 EAAARALARFAQEAE--AARVD-LQKKAQALQEECGYLRRHHQEEVGELLGQIQGSGAAQ 252
Query: 208 FQF---------AEVKEALKQREEMLEKHGI--ILNSE---------------IATNGET 241
Q +V AL++ LE H + L SE + T+
Sbjct: 253 AQMQAETRDALKCDVTSALREIRAQLEGHAVQSTLQSEEWFRVRLDRLSEAAKVNTDAMR 312
Query: 242 SDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREI------LH 295
S Y+ + EL ALKST D + SE+E +++ + I L
Sbjct: 313 SAQEEITEYRRQLQARTTELEALKSTKDSLERQRSELEDRHQADIASYQEAIQQLDAELR 372
Query: 296 NTEKEQHTED-------TVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLA-GATYEEQV 347
NT+ E + VK +DIE+ + E ++ P +L G V
Sbjct: 373 NTKWEMAAQLREYQDLLNVKMALDIEIAAYRKLLEGEECRIGFGPIPFSLPEGLPKIPSV 432
Query: 348 QSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQV 407
+ I S V+ E + + T + TE V E +
Sbjct: 433 STHIKVKSEEKIKVVEKSEKETVIVEEQTEETQV--------------TEEVTEEEEKEA 478
Query: 408 EEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHS 467
+E+ G G ++ ++ P E E ++ K +EA P E +
Sbjct: 479 KEEEGKEEE---GGEEEEAEGGEEETKSPPAE-EAASPEKEAKSPVKEEAKSPAEAKSPE 534
Query: 468 TEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPD 527
E + E + E + + P K E P +EA P+ V K P+
Sbjct: 535 KEEAKSPAEVKSPE---KAKSPAKEEAKSPPEAKSPEKEEAKSPAEV---------KSPE 582
Query: 528 EEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQV 587
+ KS + EA ++ K+ K K K+++ P E VK+E +E+K E+
Sbjct: 583 KAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEA----KSPAEVKSPEKA 638
Query: 588 KSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVL 647
KS ++ EA++ +K A+S E P +K + K ++ A V
Sbjct: 639 KSPTKE---EAKSPEKAKSPEKEEAKSPEKAKSP----VKAEAKSPEK------AKSPVK 685
Query: 648 ADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEH 707
A+ + + V+ A E + K+ AK SP + KS + PE
Sbjct: 686 AEAKSPEKAKSPVKE---EAKSPEKAKSPVKEEAK-------SPEKAKSPVKEEAKTPEK 735
Query: 708 -ESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPG-REPGHFNPESR 765
+SP ++ EA+S E+ + E K+ ++ + ++ +P + P +
Sbjct: 736 AKSPVKE-----EAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVK 790
Query: 766 EDTRGGNEKGKS--KED 780
E+ + EK KS KED
Sbjct: 791 EEVK-SPEKAKSPLKED 806
Score = 49.7 bits (117), Expect = 1e-05
Identities = 106/600 (17%), Positives = 225/600 (37%), Gaps = 52/600 (8%)
Query: 120 SGDTSISIDTEASIREIKDSLAE---VEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLL 176
S T I + +E I+ ++ S E VEE+ ++ V+ + E+ + ++
Sbjct: 431 SVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGE 490
Query: 177 ELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIA 236
E E + E + + EK A S ++ + EA +E + + + E A
Sbjct: 491 EEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKA 550
Query: 237 TNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEV----EVKN-EIVANVGKR 291
+ + + + P K + +KS E E K+ E + K
Sbjct: 551 KSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKE 610
Query: 292 EILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQI 351
E E + ++ K +++ ++ +++ A E+ +S +
Sbjct: 611 EAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPV 670
Query: 352 LESSSLPENT---VQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVE 408
+ PE V+ E+ A P S + E A + V+
Sbjct: 671 KAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPV---KEEAKSPEKAKSPVK 727
Query: 409 EQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEV---PA 465
E+A T ++ + E + L+ + + K +EA P + A
Sbjct: 728 EEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEA--KTPAKEEARSPADKFPEKA 785
Query: 466 HSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKE 525
S + E+ + D K + E+P +E P + + + + +KE
Sbjct: 786 KSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKK--------EEVKSPVKEEEKPQEVKVKE 837
Query: 526 PDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVP-VETLKDVKKELTYQN---TDLSEI 581
P ++ +++ A +++K +KK++ KK++P P VE K+ E ++ E
Sbjct: 838 PPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEA 897
Query: 582 KEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQT 641
+++++V + ++++ + + + PK+K E P++ K K K ++ +
Sbjct: 898 EDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKE----PDDAKAKEPSKPAEK----KE 949
Query: 642 AAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADR 701
AA E + DT + + + E AK++ D P++PK+E A++
Sbjct: 950 AAPE----------KKDTKEEKAKKPEEKPKTEAKAKED---DKTLSKEPSKPKAEKAEK 996
Score = 30.0 bits (66), Expect = 8.6
Identities = 90/466 (19%), Positives = 172/466 (36%), Gaps = 56/466 (12%)
Query: 3 SPAAAQSREIDCLSP---EAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSR 59
SPA A+S E SP EA+ AEA+ K A++ A E++ E + +E+ ++
Sbjct: 594 SPAEAKSPE-KAKSPVKEEAKSPAEAKSPVKEEAKSPA-EVKSPEKAKSPTKEE----AK 647
Query: 60 RSRRNTSASDEDERMSVGSRGSLRVEER-PEKDFTE-KGSRNMPGLSAATLASLGGTSSR 117
+ S E+ + ++ ++ E + PEK + K P + + + + +
Sbjct: 648 SPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEK 707
Query: 118 RGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLE 177
S + E + +K+ A+ EK K + A+ EK + TL E
Sbjct: 708 AKSPVKEEAKSPEKAKSPVKEE-AKTPEKAKSPVKEEAK-SPEKAKSPEKAKTLDVKSPE 765
Query: 178 LEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIAT 237
+ E R +K E + + + + K LK+ + EK I E+ +
Sbjct: 766 AKTPAKEEARSPADKFPEKAKSPVKEEVKSPE--KAKSPLKEDAKAPEKE-IPKKEEVKS 822
Query: 238 NGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNT 297
+ + V + P K +EE + E K + ++
Sbjct: 823 PVKEEEKPQEVKVKEPPKKAEEE----------KAPATPKTEEKKDSKKEEAPKKEAPKP 872
Query: 298 EKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQI-LESSS 356
+ E+ E V+ + +V E ED+K T E++ +++ ++ +
Sbjct: 873 KVEEKKEPAVEKPKESKVEAKKEEAEDKKKV------------PTPEKEAPAKVEVKEDA 920
Query: 357 LPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVAS 416
P+ +V E PDD EPS + ++ E + EE+ T A
Sbjct: 921 KPKEKTEVAKKE----PDDAKAK--EPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAK 974
Query: 417 CPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKE 462
DDK + + P + + + T+Q+ ++P E
Sbjct: 975 AK---------EDDKTLSKEPSKPKAEKAE--KSSSTDQKDSKPPE 1009
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 59.7 bits (143), Expect = 1e-08
Identities = 75/365 (20%), Positives = 135/365 (36%), Gaps = 30/365 (8%)
Query: 435 EVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEV 494
E ++ E GH E+ NQE E E E EEE E+ G E+ EV
Sbjct: 708 EEQEQKEREQGHQKER---NQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEV 764
Query: 495 PGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKK 554
G EG ++ + E D E +EE+++ +GE + + + ++ K
Sbjct: 765 EGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKG 824
Query: 555 KKSPVPVETLKDV-------------------KKELTYQNTDLSEIKEEEQVKSTDRKSA 595
++ E + K E + + E EE + + + +
Sbjct: 825 EREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGE 884
Query: 596 VEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDF 655
E + E +++ E E + + +GK ++EG++ + EE +G+ D
Sbjct: 885 GEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDG 944
Query: 656 EDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDIS 715
E + + G G EE EG ++ +G + E + E+ + E E ++
Sbjct: 945 EGEGEEEEGEWEGEEEEGEGEGEE----EGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGE 1000
Query: 716 DACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGNEKG 775
+ E E E E V ++ E + G E G E RE G E
Sbjct: 1001 EEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEG----EEREKEGEGEENR 1056
Query: 776 KSKED 780
+++E+
Sbjct: 1057 RNREE 1061
Score = 47.8 bits (112), Expect = 4e-05
Identities = 72/375 (19%), Positives = 138/375 (36%), Gaps = 50/375 (13%)
Query: 432 CMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEE----GEETGLRDE 487
C V Q + + + + F+++E P+E G E+E E +
Sbjct: 559 CKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGG 618
Query: 488 KPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKN 547
+ KTE+ + E S + ++ P E + D E S + ++
Sbjct: 619 RKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGP-------EGRGDGTCEEGSSGAEHWQD 671
Query: 548 KKK-KNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENP 606
+++ K +K K +E + +KEL + EE++ K ++ E E+ E
Sbjct: 672 EEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGG 731
Query: 607 KQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLA----------------DG 650
+++ E D E + + +GK + EG++V+ E+ +G
Sbjct: 732 EEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEG 791
Query: 651 DTLDFEDDTVQSSG--PRAGGE----ELDEGVA-KDNAKIDGATQSSPAEPKSEDADRCT 703
D + E++ + G GGE E++EG ++ + +G + E + E+ +
Sbjct: 792 DQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEG-- 849
Query: 704 LPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPE 763
E E + + E E E E E E ++ G E G E
Sbjct: 850 -EEEEGEGKGEEEGEEGEGEEEGEEGEGEG------------EEEEGEGEGEEEGEGEGE 896
Query: 764 SREDTRGGNEKGKSK 778
E G E+G+ +
Sbjct: 897 EEEGEGEGEEEGEGE 911
Score = 42.4 bits (98), Expect = 0.002
Identities = 72/317 (22%), Positives = 131/317 (41%), Gaps = 37/317 (11%)
Query: 475 NEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQ 534
+E +E+ L ++ ++ E P E STV++ E D+ S
Sbjct: 451 SERNLQESVLSEQDLMQPEEPDYLLDEMTKEAEIDNSSTVESLGETTDILNMTHIMS--- 507
Query: 535 GEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTY-QNTDLSEIKEEEQVKSTDRK 593
L+S++K K + +KK+ +T+ ++ ++ +N D E +E ++K
Sbjct: 508 ---LNSNEKSLKLSPVQKQKKQ-----QTIGELTQDTALTENDDSDEYEEMSEMKEGKAC 559
Query: 594 SAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTL 653
+Q P I A S E V+ PE + +G D +G+ ++ +EV A+
Sbjct: 560 KQHVSQGIFMTQPATTIEAFSDEEVEIPE----EKEGAEDSKGNGIE--EQEVEAN---- 609
Query: 654 DFEDDTVQSSGPRAGGEELDEGVAKDNAKI-DGATQS-SPAEPKSEDADRCTLPEHESPS 711
++ V+ G R E+ D A++ +G +S AE E T E S +
Sbjct: 610 ---EENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGA 666
Query: 712 QDISDACEAESTE----RCEMSEHPSQTVRKALDS---NSLENDDLSAPGREPGHFNPES 764
+ D E E E R EM E P + ++ + + ++ RE GH +
Sbjct: 667 EHWQDE-EREKGEKDKGRGEM-ERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERN 724
Query: 765 REDTRGGNEK-GKSKED 780
+E GG E+ G+ +E+
Sbjct: 725 QEMEEGGEEEHGEGEEE 741
Score = 40.0 bits (92), Expect = 0.008
Identities = 89/420 (21%), Positives = 145/420 (34%), Gaps = 49/420 (11%)
Query: 179 EEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATN 238
EEQ + R Q +K + E E+ + E +E REE EK G E
Sbjct: 708 EEQEQKEREQGHQKERNQEMEEGGEE----EHGEGEEEEGDREEEEEKEG-----EGKEE 758
Query: 239 GETSDTLNNVGYQ----------GPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANV 288
GE + + G + +EE + + + T GR E E E+
Sbjct: 759 GEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGE 818
Query: 289 GKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQ-KSSEDTAPFLGTLAGATYEEQV 347
+ E+E+ E ++ E GE E + K E+ G G E +
Sbjct: 819 VEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEG 878
Query: 348 QSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQV 407
+ + E E + E E G ++ E + +G E GE +
Sbjct: 879 EEEEGEGEGEEEGEGEGEEEEGEGEGEE------EGEGEGEEEEGEGKGEEEGEEGEGEG 932
Query: 408 EEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEK-EFTNQEAAEPKEVPAH 466
EE+ G G +D ++ E E E G E+ E +E E
Sbjct: 933 EEEEGE------GEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEG 986
Query: 467 STEVGRDHNEEEGEETGLRDEK-----------PIKTEVPGSPAGTEGNCQEATGPSTV- 514
E + EEEGEE G +E+ ++ EV G EG +E
Sbjct: 987 EGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEER 1046
Query: 515 ----DTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKE 570
+ + + +E +EE+ Q + ++++ + KK K K V K +K+
Sbjct: 1047 EKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKK 1106
Score = 35.4 bits (80), Expect = 0.21
Identities = 125/604 (20%), Positives = 207/604 (34%), Gaps = 77/604 (12%)
Query: 1 MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR 60
MT PA I+ S E ++ E + A+ +++ ++E E + EE+ + + R
Sbjct: 569 MTQPATT----IEAFSDEEVEIPEEKEGAE-----DSKGNGIEEQEVEANEENVKVHGGR 619
Query: 61 SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMP-GLSAATLASLGGTSSRRG 119
+ SD+ + S G + E +G G S A R
Sbjct: 620 KEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAE----HWQDEERE 675
Query: 120 SGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELE 179
G+ E + LAE EE K+ Q + E+ +Q + ++M E
Sbjct: 676 KGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQG---HQKERNQEMEEGGE 732
Query: 180 EQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVK------EALKQREEMLEKH------ 227
E+ E EE ++E E EK + + EV+ E +++EE K
Sbjct: 733 EEHGEGEE--EEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEE 790
Query: 228 ---GIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTL--GRASEVEVKN 282
G E GE + V G + K E + G+G G E E +
Sbjct: 791 GDQGEGEEEETEGRGEEKEEGGEVE-GGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEG 849
Query: 283 EIVANVGK-REILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGA 341
E GK E E E+ E+ + + E GE + + E+ G G
Sbjct: 850 EEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGE 909
Query: 342 TYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWS------DLDGGNH 395
E+ + + E + E E G +D E W + +G
Sbjct: 910 GEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEE 969
Query: 396 TENVGEAAVTQVEEQAGTVASCPL-----------GHSDDTVYHDDKCMVEVPQELETST 444
E GE + EE+ G G + +++ EV E+E
Sbjct: 970 GEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEE 1029
Query: 445 GHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGN 504
G +E +E E +E E R+ EEE E EG
Sbjct: 1030 GEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEE---------------------EGK 1068
Query: 505 CQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETL 564
QE TG + Q+ K + S + G+ +K N + K+++S +PV++
Sbjct: 1069 YQE-TGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKMPVQSK 1127
Query: 565 KDVK 568
+ +K
Sbjct: 1128 RLLK 1131
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 58.2 bits (139), Expect = 3e-08
Identities = 79/378 (20%), Positives = 149/378 (39%), Gaps = 56/378 (14%)
Query: 422 SDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEV----------G 471
SDDT+ ++ + + +T S +E N++ + K ST+ G
Sbjct: 140 SDDTIQASEESAPQGQDSAQDTTSES--RELDNEDRVDSKPEGGDSTQESESEEHWVGGG 197
Query: 472 RDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKS 531
D G+ + L DE ++++ P S GN ++ MK + ++
Sbjct: 198 SDGESSHGDGSELDDEG-MQSDDPESIRSERGN-----------SRMNSAGMKSKESGEN 245
Query: 532 DQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTD 591
+Q DS + + +KS + E D + EL NT + E+K + S
Sbjct: 246 SEQANTQDSGGSQLLEHPSRKIFRKSRISEE---DDRSELDDNNT-MEEVKSDSTENSNS 301
Query: 592 RKSAV-----EAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEV 646
R + + +++ + E+ K+ ++ E S+NVD P + + QE + EEV
Sbjct: 302 RDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSS--ESQEEV 359
Query: 647 LAD--GD----TLDFEDDTVQSSGPR---------AGGEELDEGVAKDNAKIDGATQSSP 691
+++ GD T + +D S + E +E ++++ ++ SP
Sbjct: 360 VSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESP 419
Query: 692 AEPKSEDADRCT-LPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDL 750
P+ E++ L H S ++ S+ +E E + R DSNS E+
Sbjct: 420 ESPEDENSSSQEGLQSHSSSAESQSEESHSE-----EDDSDSQDSSRSKEDSNSTESKSS 474
Query: 751 SAPGREPGHFNPESREDT 768
S + + ESR+ T
Sbjct: 475 SEEDGQLKNIEIESRKLT 492
Score = 47.0 bits (110), Expect = 7e-05
Identities = 72/422 (17%), Positives = 163/422 (38%), Gaps = 42/422 (9%)
Query: 320 ENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRT 379
++ ++ S +DT + G ++ + L S ++T+Q D T
Sbjct: 102 KDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDT 161
Query: 380 PLEPSNCWSDLDGGNHTENVGEAAVTQVEEQA-----GTVASCPLGHSDDTVYHDDKCMV 434
E +LD + ++ E + E ++ G + H D + D+
Sbjct: 162 TSESR----ELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQS 217
Query: 435 EVPQELETSTGHSL--------------EKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGE 480
+ P+ + + G+S ++ Q++ + + S ++ R E +
Sbjct: 218 DDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEED 277
Query: 481 ETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDS 540
+ D+ EV TE + TG S ++ ++ E S ++ + +D
Sbjct: 278 DRSELDDNNTMEEVKSD--STENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDG 335
Query: 541 SQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTD--LSEIKEEEQVKSTDRKSAVEA 598
++ + + ++ S E+ ++V E N D S ++++E S++ S+
Sbjct: 336 PSSESSQEANLSSQENSS---ESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTL 392
Query: 599 QNEVTENPKQKIAAESSENV----DCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLD 654
+ +E+ +++ +ESSE++ + PE+P+ + QEG +Q+ + + +
Sbjct: 393 SHSKSESREEQADSESSESLNFSEESPESPED--ENSSSQEG--LQSHSSSAESQSEESH 448
Query: 655 FEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDI 714
E+D S E+ + +K +++ DG ++ E + D H P D
Sbjct: 449 SEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVD----AYHNKPIGDQ 504
Query: 715 SD 716
D
Sbjct: 505 DD 506
Score = 31.6 bits (70), Expect = 3.0
Identities = 43/200 (21%), Positives = 74/200 (37%), Gaps = 26/200 (13%)
Query: 594 SAVEAQNEVTENPKQKIAAESSENVDCPENPKI-KLDGKL--------DQEGDDVQTAAE 644
S V ++ + E+P + +S E + ++ I +L G D + DD + +
Sbjct: 54 SKVSSEEQANEDPSD--STQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGD 111
Query: 645 EVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTL 704
+ D D+ D + R G +E + D S + P+ +D+ + T
Sbjct: 112 DTFGDDDSGPGPKDRQEGGNSRLGSDEDSD---------DTIQASEESAPQGQDSAQDTT 162
Query: 705 PE-HESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPE 763
E E ++D D+ + E + + SE V D S D +PE
Sbjct: 163 SESRELDNEDRVDS-KPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPE 221
Query: 764 SREDTRGGNEKG----KSKE 779
S RG + KSKE
Sbjct: 222 SIRSERGNSRMNSAGMKSKE 241
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 58.2 bits (139), Expect = 3e-08
Identities = 79/378 (20%), Positives = 149/378 (39%), Gaps = 56/378 (14%)
Query: 422 SDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEV----------G 471
SDDT+ ++ + + +T S +E N++ + K ST+ G
Sbjct: 124 SDDTIQASEESAPQGQDSAQDTTSES--RELDNEDRVDSKPEGGDSTQESESEEHWVGGG 181
Query: 472 RDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKS 531
D G+ + L DE ++++ P S GN ++ MK + ++
Sbjct: 182 SDGESSHGDGSELDDEG-MQSDDPESIRSERGN-----------SRMNSAGMKSKESGEN 229
Query: 532 DQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTD 591
+Q DS + + +KS + E D + EL NT + E+K + S
Sbjct: 230 SEQANTQDSGGSQLLEHPSRKIFRKSRISEE---DDRSELDDNNT-MEEVKSDSTENSNS 285
Query: 592 RKSAV-----EAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEV 646
R + + +++ + E+ K+ ++ E S+NVD P + + QE + EEV
Sbjct: 286 RDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSS--ESQEEV 343
Query: 647 LAD--GD----TLDFEDDTVQSSGPR---------AGGEELDEGVAKDNAKIDGATQSSP 691
+++ GD T + +D S + E +E ++++ ++ SP
Sbjct: 344 VSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESP 403
Query: 692 AEPKSEDADRCT-LPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDL 750
P+ E++ L H S ++ S+ +E E + R DSNS E+
Sbjct: 404 ESPEDENSSSQEGLQSHSSSAESQSEESHSE-----EDDSDSQDSSRSKEDSNSTESKSS 458
Query: 751 SAPGREPGHFNPESREDT 768
S + + ESR+ T
Sbjct: 459 SEEDGQLKNIEIESRKLT 476
Score = 47.0 bits (110), Expect = 7e-05
Identities = 72/422 (17%), Positives = 163/422 (38%), Gaps = 42/422 (9%)
Query: 320 ENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRT 379
++ ++ S +DT + G ++ + L S ++T+Q D T
Sbjct: 86 KDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDT 145
Query: 380 PLEPSNCWSDLDGGNHTENVGEAAVTQVEEQA-----GTVASCPLGHSDDTVYHDDKCMV 434
E +LD + ++ E + E ++ G + H D + D+
Sbjct: 146 TSESR----ELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQS 201
Query: 435 EVPQELETSTGHSL--------------EKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGE 480
+ P+ + + G+S ++ Q++ + + S ++ R E +
Sbjct: 202 DDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEED 261
Query: 481 ETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDS 540
+ D+ EV TE + TG S ++ ++ E S ++ + +D
Sbjct: 262 DRSELDDNNTMEEVKSD--STENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDG 319
Query: 541 SQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTD--LSEIKEEEQVKSTDRKSAVEA 598
++ + + ++ S E+ ++V E N D S ++++E S++ S+
Sbjct: 320 PSSESSQEANLSSQENSS---ESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTL 376
Query: 599 QNEVTENPKQKIAAESSENV----DCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLD 654
+ +E+ +++ +ESSE++ + PE+P+ + QEG +Q+ + + +
Sbjct: 377 SHSKSESREEQADSESSESLNFSEESPESPED--ENSSSQEG--LQSHSSSAESQSEESH 432
Query: 655 FEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDI 714
E+D S E+ + +K +++ DG ++ E + D H P D
Sbjct: 433 SEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVD----AYHNKPIGDQ 488
Query: 715 SD 716
D
Sbjct: 489 DD 490
Score = 30.4 bits (67), Expect = 6.6
Identities = 34/152 (22%), Positives = 55/152 (36%), Gaps = 15/152 (9%)
Query: 633 DQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPA 692
D + DD + ++ D D+ D + R G +E + D S +
Sbjct: 84 DDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSD---------DTIQASEES 134
Query: 693 EPKSEDADRCTLPE-HESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLS 751
P+ +D+ + T E E ++D D+ + E + + SE V D S D
Sbjct: 135 APQGQDSAQDTTSESRELDNEDRVDS-KPEGGDSTQESESEEHWVGGGSDGESSHGDGSE 193
Query: 752 APGREPGHFNPESREDTRGGNEKG----KSKE 779
+PES RG + KSKE
Sbjct: 194 LDDEGMQSDDPESIRSERGNSRMNSAGMKSKE 225
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 57.0 bits (136), Expect = 7e-08
Identities = 132/675 (19%), Positives = 265/675 (39%), Gaps = 102/675 (15%)
Query: 7 AQSREIDCLSPEAQKLAE--ARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRN 64
A ++ L+ E L E A+L ++ A EA + + +L Q EED +
Sbjct: 976 ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDL---QAEED------KVNTL 1026
Query: 65 TSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTS 124
T A + E+ GSL E++ D + R+ GD
Sbjct: 1027 TKAKIKLEQQVDDLEGSLEQEKKLRMDLER--------------------AKRKLEGDLK 1066
Query: 125 ISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAE 184
++ + SI +I++ +++EK KK + E +N +++ + + ++L++++ E
Sbjct: 1067 LA---QESIMDIENEKQQLDEKLKKK-------EFEISNLQSKIEDEQALGIQLQKKIKE 1116
Query: 185 SRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDT 244
+ + EE +E E E+ + + + Q +++ L++ E LE+ G +++I N +
Sbjct: 1117 LQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAE 1176
Query: 245 LNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTE 304
+ + EE TL + + VA +G++ + N ++ +
Sbjct: 1177 FQKM------RRDLEEATLQHEATAATLRKKHA-----DSVAELGEQ--IDNLQRVKQKL 1223
Query: 305 DTVKDCVDIEVFPAGENTED-QKSSEDTAPFLGTLAGATYE----EQVQSQILESSSLPE 359
+ K + +E+ N E K+ + TL E E+ Q +++ +
Sbjct: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283
Query: 360 NTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNH--TENVGEAAVTQVEEQAGTVASC 417
+Q ES E D++ S L G T+ + E Q+EE+ A
Sbjct: 1284 GRLQTESGEFSRQLDEKEALV-------SQLSRGKQAFTQQIEELK-RQLEEEIK--AKN 1333
Query: 418 PLGHSDDTVYHDDKCM---VEVPQELETSTGHSLEKEFTN----------------QEAA 458
L H+ + HD + E QE + +L K T +E
Sbjct: 1334 ALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELE 1393
Query: 459 EPKEVPAHSTEVGRDHNEEEGEETGL--RDEKPIKTEVPGSPAGTEGNCQEATGPSTVDT 516
E K+ A + +H E + + ++ ++ EV E + + +D
Sbjct: 1394 EAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVE---RTNAACAALDK 1450
Query: 517 QNEPLDMKEPD-EEKSDQQGEALDSSQKKTKNK-----KKKNKKKKSPVPVETLKDVKKE 570
+ D + ++K ++ L++SQK+ ++ K KN ++S +ETLK K
Sbjct: 1451 KQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKN 1510
Query: 571 LTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDG 630
L + +DL+E + E K ++ Q E + Q E+ +++ E +++
Sbjct: 1511 LQQEISDLTE-QIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQL 1569
Query: 631 KLDQEGDDVQTAAEE 645
+L+Q +V E
Sbjct: 1570 ELNQVKSEVDRKIAE 1584
Score = 43.1 bits (100), Expect = 0.001
Identities = 62/307 (20%), Positives = 115/307 (37%), Gaps = 33/307 (10%)
Query: 3 SPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSR 62
S A A+ + D LS E ++++E A A A+ + +E E Q+ D E + +
Sbjct: 1134 SRAKAEKQRSD-LSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHE 1192
Query: 63 RNTSASDEDERMSVGSRGSL-----RVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSR 117
+ + SV G RV+++ EK+ +E + LAS T S+
Sbjct: 1193 ATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMK------MEIDDLASNVETVSK 1246
Query: 118 RGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLE 177
+ E + E+K E + +L E F Q+D + ++ +
Sbjct: 1247 AKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQ 1306
Query: 178 LEEQLAESRRQYEEKNKEFERE--------------KHAHSILQFQFAEVKEALKQREEM 223
L +Q EE ++ E E +H +L+ Q+ E +E+ + +
Sbjct: 1307 LSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRA 1366
Query: 224 LEKHGIILNSEIA---TNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEV 280
L K N+E+A T ET + K + L A + + + + +E
Sbjct: 1367 LSK----ANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEK 1422
Query: 281 KNEIVAN 287
+ + N
Sbjct: 1423 TKQRLQN 1429
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 57.0 bits (136), Expect = 7e-08
Identities = 132/675 (19%), Positives = 265/675 (39%), Gaps = 102/675 (15%)
Query: 7 AQSREIDCLSPEAQKLAE--ARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRN 64
A ++ L+ E L E A+L ++ A EA + + +L Q EED +
Sbjct: 976 ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDL---QAEED------KVNTL 1026
Query: 65 TSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTS 124
T A + E+ GSL E++ D + R+ GD
Sbjct: 1027 TKAKIKLEQQVDDLEGSLEQEKKLRMDLER--------------------AKRKLEGDLK 1066
Query: 125 ISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAE 184
++ + SI +I++ +++EK KK + E +N +++ + + ++L++++ E
Sbjct: 1067 LA---QESIMDIENEKQQLDEKLKKK-------EFEISNLQSKIEDEQALGIQLQKKIKE 1116
Query: 185 SRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDT 244
+ + EE +E E E+ + + + Q +++ L++ E LE+ G +++I N +
Sbjct: 1117 LQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAE 1176
Query: 245 LNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTE 304
+ + EE TL + + VA +G++ + N ++ +
Sbjct: 1177 FQKM------RRDLEEATLQHEATAATLRKKHA-----DSVAELGEQ--IDNLQRVKQKL 1223
Query: 305 DTVKDCVDIEVFPAGENTED-QKSSEDTAPFLGTLAGATYE----EQVQSQILESSSLPE 359
+ K + +E+ N E K+ + TL E E+ Q +++ +
Sbjct: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283
Query: 360 NTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNH--TENVGEAAVTQVEEQAGTVASC 417
+Q ES E D++ S L G T+ + E Q+EE+ A
Sbjct: 1284 GRLQTESGEFSRQLDEKEALV-------SQLSRGKQAFTQQIEELK-RQLEEEIK--AKN 1333
Query: 418 PLGHSDDTVYHDDKCM---VEVPQELETSTGHSLEKEFTN----------------QEAA 458
L H+ + HD + E QE + +L K T +E
Sbjct: 1334 ALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELE 1393
Query: 459 EPKEVPAHSTEVGRDHNEEEGEETGL--RDEKPIKTEVPGSPAGTEGNCQEATGPSTVDT 516
E K+ A + +H E + + ++ ++ EV E + + +D
Sbjct: 1394 EAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVE---RTNAACAALDK 1450
Query: 517 QNEPLDMKEPD-EEKSDQQGEALDSSQKKTKNK-----KKKNKKKKSPVPVETLKDVKKE 570
+ D + ++K ++ L++SQK+ ++ K KN ++S +ETLK K
Sbjct: 1451 KQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKN 1510
Query: 571 LTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDG 630
L + +DL+E + E K ++ Q E + Q E+ +++ E +++
Sbjct: 1511 LQQEISDLTE-QIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQL 1569
Query: 631 KLDQEGDDVQTAAEE 645
+L+Q +V E
Sbjct: 1570 ELNQVKSEVDRKIAE 1584
Score = 43.1 bits (100), Expect = 0.001
Identities = 62/307 (20%), Positives = 115/307 (37%), Gaps = 33/307 (10%)
Query: 3 SPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSR 62
S A A+ + D LS E ++++E A A A+ + +E E Q+ D E + +
Sbjct: 1134 SRAKAEKQRSD-LSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHE 1192
Query: 63 RNTSASDEDERMSVGSRGSL-----RVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSR 117
+ + SV G RV+++ EK+ +E + LAS T S+
Sbjct: 1193 ATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMK------MEIDDLASNVETVSK 1246
Query: 118 RGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLE 177
+ E + E+K E + +L E F Q+D + ++ +
Sbjct: 1247 AKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQ 1306
Query: 178 LEEQLAESRRQYEEKNKEFERE--------------KHAHSILQFQFAEVKEALKQREEM 223
L +Q EE ++ E E +H +L+ Q+ E +E+ + +
Sbjct: 1307 LSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRA 1366
Query: 224 LEKHGIILNSEIA---TNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEV 280
L K N+E+A T ET + K + L A + + + + +E
Sbjct: 1367 LSK----ANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEK 1422
Query: 281 KNEIVAN 287
+ + N
Sbjct: 1423 TKQRLQN 1429
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 57.0 bits (136), Expect = 7e-08
Identities = 97/430 (22%), Positives = 166/430 (38%), Gaps = 48/430 (11%)
Query: 340 GATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENV 399
G+ +E+ +Q + ++ Q + E + AP+ E + G+ E
Sbjct: 1807 GSGHEDNLQGEAAAGGD--QDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAE 1864
Query: 400 GEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAE 459
GEA + +A S+D + EV E E + EKE E
Sbjct: 1865 GEAQPESEDVEAPEAEGEAQPESEDV--ETPEAEWEVQPESEGAEAPEAEKE----AQPE 1918
Query: 460 PKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNE 519
+ V A TE G D E EG E +E + E P QEA ++E
Sbjct: 1919 TESVEALETE-GEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAE--EEAQPESE 1975
Query: 520 PLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDL- 578
++ E + E + +GEA S+ ++P +++ ++E ++ +
Sbjct: 1976 DVEALEVEVETQEAEGEAQPESEDV-----------EAPEAEGEMQEAEEEAQPESDGVE 2024
Query: 579 ----SEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQ 634
SE +E ++V+ +K+ +AQ E A E+ E E + +G+
Sbjct: 2025 AQPKSEGEEAQEVEGETQKTEGDAQPESDGVE----APEAEEEAQEAEGEVQEAEGEAHP 2080
Query: 635 EGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEP 694
E +DV A+E A+G+ + ++ P A EG A+ I+ A+P
Sbjct: 2081 ESEDVD--AQE--AEGEA---QPESEGVEAPEA------EGEAQKAEGIEAPETEGEAQP 2127
Query: 695 KSEDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPG 754
+SE + PE E +Q S+ EA+ E E ++A + E + + AP
Sbjct: 2128 ESEGIE---APEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPE 2184
Query: 755 REPGHFNPES 764
E G PES
Sbjct: 2185 AE-GEAQPES 2193
Score = 51.2 bits (121), Expect = 4e-06
Identities = 107/546 (19%), Positives = 207/546 (37%), Gaps = 76/546 (13%)
Query: 197 EREKHAHSILQFQFAEVKEALKQREEMLEK---------HGIILNSEIATNGET------ 241
ERE H+ +E+ EA ++ E + E+ H L E A G+
Sbjct: 1771 EREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSD 1830
Query: 242 -SDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKE 300
++ + +G + E + A ++ GD ++ A + E +
Sbjct: 1831 GAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEA------Q 1884
Query: 301 QHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLA-------------GATYEEQV 347
+ED + EV P E E ++ ++ P ++ GA +E
Sbjct: 1885 PESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAE 1944
Query: 348 QS-QILESSSLPENTVQVESNEVM--GAPDDRTRTPLEPSNCWSDLDGGNHTENVG-EAA 403
++ Q E + PE+ V +ES E P+ LE + +G E+ EA
Sbjct: 1945 EAAQEAEGQTQPESEV-IESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAP 2003
Query: 404 VTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEV 463
+ E Q + P D V K E QE+E T + + A+P+
Sbjct: 2004 EAEGEMQEAEEEAQP---ESDGVEAQPKSEGEEAQEVEGETQKT-------EGDAQPESD 2053
Query: 464 PAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDM 523
+ E + E EGE + E P + + QEA G + Q E +
Sbjct: 2054 GVEAPEAEEEAQEAEGEVQ--------EAEGEAHPESEDVDAQEAEG----EAQPESEGV 2101
Query: 524 KEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKE 583
+ P+ E Q+ E +++ + + + + +++ ++P + + + Q+ + E
Sbjct: 2102 EAPEAEGEAQKAEGIEAPETEGE-AQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPE 2160
Query: 584 EEQVKSTDRKSAVEAQNEVTENPKQKIAAE-SSENVDCPENPKIKLDGKLDQEGDDVQTA 642
E +++ + + + + E E P+ + A+ SE ++ PE + + + + EG + A
Sbjct: 2161 SEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPE---AEGEAQPELEGVEAPEA 2217
Query: 643 AEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRC 702
EE + + ++ P A GE E + + G+ Q S + +SE+A
Sbjct: 2218 EEEAQPEPEGVET---------PEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASES 2268
Query: 703 TLPEHE 708
+ P E
Sbjct: 2269 SSPVPE 2274
Score = 40.4 bits (93), Expect = 0.006
Identities = 50/219 (22%), Positives = 90/219 (41%), Gaps = 22/219 (10%)
Query: 574 QNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLD 633
+NT E++ EE + T+ + E ++ E ++ E E V E + + +G+ +
Sbjct: 1294 ENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQE--EGVQLEETKETEGEGQQE 1351
Query: 634 QEG---DDVQTAAEEVLADGDTLDFEDDTVQSSGPRAG--GEELDEGVAKDNAKIDGA-- 686
+E + +T E + +G L+ + GP G GE L+EG+ ++ +G+
Sbjct: 1352 EEAQLEEIEETGGEGLQEEGVQLEEVKE-----GPEGGLQGEALEEGLKEEGLPEEGSVH 1406
Query: 687 ----TQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTER-CEMSEHPSQTVRKALD 741
+++S + K D E + ++ C AE TE E H S+T A +
Sbjct: 1407 GQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEPPSHLSETDPSASE 1466
Query: 742 SNS---LENDDLSAPGREPGHFNPESREDTRGGNEKGKS 777
S LE PG + T+G E+ S
Sbjct: 1467 RQSGSQLEPGLEKPPGATMMGQEHTQAQPTQGAAERSSS 1505
Score = 36.6 bits (83), Expect = 0.092
Identities = 132/639 (20%), Positives = 221/639 (34%), Gaps = 91/639 (14%)
Query: 180 EQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNG 239
EQLAE+ Q EE E +E LQ + +++E + EE L++ G+ L T G
Sbjct: 1290 EQLAENTVQ-EEVQLEETKEGTEGEGLQEEAVQLEET--KTEEGLQEEGVQLEETKETEG 1346
Query: 240 ETSDT----LNNVGYQGPTKMTKE--ELNALKSTGDGTL-GRASEVEVKNEIVANVGKRE 292
E L + G + +E +L +K +G L G A E +K E + G
Sbjct: 1347 EGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGS-- 1404
Query: 293 ILHNTE---------KEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAP--FLGTLAGA 341
+H E K +D V++ + E + + E T P L +
Sbjct: 1405 -VHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEPPSHLSETDPS 1463
Query: 342 TYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENV-- 399
E Q SQ+ P + P C + LD +V
Sbjct: 1464 ASERQSGSQLEPGLEKPPGATMMGQEHTQAQPTQGAAERSSSVACSAALDCDPIWVSVLL 1523
Query: 400 --GEAAVTQVEEQAGTVASCPLGHSDDTVYHD--DKCMVEVPQELETSTGHSLEK---EF 452
E A A G D+ + + +V Q L+ ST L+K
Sbjct: 1524 KKTEKAFLAHLASAVAELRARWGLQDNDLLDQMAAELQQDVAQRLQDSTKRELQKLQGRA 1583
Query: 453 TNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPS 512
P+E A + E+ + GLR+ G GP
Sbjct: 1584 GRMVLEPPRE--ALTGELLLQTQQRRHRLRGLRNLSAFSERTLG------------LGPL 1629
Query: 513 TVDTQNEP-LDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKEL 571
+ ++EP L + + +GE + + KK SP+ + +
Sbjct: 1630 SFTLEDEPALSTALGSQLGEEAEGEEFCPCEACVR-------KKVSPMSPKATMGATRGP 1682
Query: 572 TYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCP---ENPKIKL 628
+ DL +I + ++ + TD ++A A + +P + +E P + P +
Sbjct: 1683 IKEAFDLQQILQRKRGEHTDGEAAEVAPGKTHTDPTSTRTVQGAEGGLGPGLSQGPGV-- 1740
Query: 629 DGKLDQEGDDVQTAAEEVL---ADGDTLDFEDDTVQSSGPRAGGEEL------DEGVA-- 677
D D EG ++ A+GD + E + + + G EL EG++
Sbjct: 1741 DEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISER 1800
Query: 678 ----------KDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTERCE 727
+DN + + A +S+ A+ PE E +Q S+ EA E
Sbjct: 1801 GETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAE--- 1857
Query: 728 MSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESRE 766
++A E++D+ AP E G PES +
Sbjct: 1858 ------GDAQEAEGEAQPESEDVEAPEAE-GEAQPESED 1889
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 56.2 bits (134), Expect = 1e-07
Identities = 135/653 (20%), Positives = 269/653 (41%), Gaps = 73/653 (11%)
Query: 10 REIDCLSPEAQKLAEARLAAKRAARAEAREIRMKE--LERQQKEEDSERYSRRSRRNTSA 67
R+ID L K+ + + A + + + E+ E + + KE+ S + + + +
Sbjct: 956 RDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQ 1015
Query: 68 SDEDERMSVGSRGSLRVEERPEKDFTE-KGSRNMPGLSAATLASLGGTSSRRGSGDTSIS 126
+ED+ G +++ + E+ + +GS A L + R+ GD +S
Sbjct: 1016 VEEDK-----VNGLIKINAKLEQQTDDLEGSLEQEKKLRADLER----AKRKLEGDLKMS 1066
Query: 127 IDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESR 186
+ SI ++++ ++EEK KK +QL ++D + L+ ++++ E +
Sbjct: 1067 ---QESIMDLENDKQQIEEKLKKKEFELSQL-------QAKIDDEQVHSLQFQKKIKELQ 1116
Query: 187 RQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLN 246
+ EE +E E E + ++ Q +++ L++ E LE+ +++I N +
Sbjct: 1117 ARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQ 1176
Query: 247 NVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDT 306
+ + EE TL + + + VA +G E + N ++ + +
Sbjct: 1177 KM------RRDLEEATLQHEATAATLRKK-----QADSVAELG--EQIDNLQRVKQKLEK 1223
Query: 307 VKDCVDIEVFPAGENTED-QKSSEDTAPFLGTLAGATYE----EQVQSQILESSSLPENT 361
K + +E+ N E KS + T+ E ++ Q+Q++ ++ +
Sbjct: 1224 EKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKAR 1283
Query: 362 VQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGH 421
+Q ++ E+ +++ + + L T+ + E Q+EE+ T A + H
Sbjct: 1284 LQTQNGELSHRVEEKESLISQLTKSKQAL-----TQQL-EELKRQMEEE--TKAKNAMAH 1335
Query: 422 SDDTVYHDDKCM---VEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEE 478
+ + HD + E QE + +L K N E A+ + E EE
Sbjct: 1336 ALQSSRHDCDLLREQYEEEQEAKAELQRALSK--ANSEVAQWRT----KYETDAIQRTEE 1389
Query: 479 GEETGLRDEKPIKTEVPGSPAGTE-GNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEA 537
EE +K + + + TE N + A+ T ++ D E+S
Sbjct: 1390 LEEA----KKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACAT 1445
Query: 538 LDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKE--EEQVK--STDRK 593
LD Q+ + K+K E L+ +KE +T+L +++ EE V T R+
Sbjct: 1446 LDKKQRNFDKVLAEWKQKLDESQAE-LEAAQKESRSLSTELFKMRNAYEEVVDQLETLRR 1504
Query: 594 SAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEV 646
Q E+++ +Q AE+ +N+ E K KL ++QE D+Q A EEV
Sbjct: 1505 ENKNLQEEISDLTEQ--IAETGKNLQEAEKTK-KL---VEQEKSDLQVALEEV 1551
Score = 37.7 bits (86), Expect = 0.041
Identities = 41/226 (18%), Positives = 97/226 (42%), Gaps = 11/226 (4%)
Query: 6 AAQSREIDC--LSPEAQKLAEARLAAKRA---ARAEAREIRMK-ELERQQKEEDSERYSR 59
A QS DC L + ++ EA+ +RA A +E + R K E + Q+ E+ E +
Sbjct: 1336 ALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKK 1395
Query: 60 RSRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRG 119
+ + ++E+ + SL ++ + E R++ A T ++
Sbjct: 1396 KLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTAC-----ATLDKKQ 1450
Query: 120 SGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELE 179
+ + + + E + L +++ + ++ N + Q++TL+ L+
Sbjct: 1451 RNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQ 1510
Query: 180 EQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLE 225
E++++ Q E K + + +++ + ++++ AL++ E LE
Sbjct: 1511 EEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLE 1556
Score = 30.8 bits (68), Expect = 5.1
Identities = 37/163 (22%), Positives = 72/163 (44%), Gaps = 25/163 (15%)
Query: 130 EASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDML-----------LEL 178
+ I ++ + +AE + ++A + ++ EK++ ++ ++ L LEL
Sbjct: 1510 QEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLEL 1569
Query: 179 EEQLAESRRQYEEKNKEFEREKH--------AHSILQFQFAEVKEALKQREEM---LEKH 227
+ +E R+ EK++E E+ K S+L + +AL+ +++M L +
Sbjct: 1570 SQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEM 1629
Query: 228 GIILNSEIATNGETSDTLNNVGYQGPTKMTKEEL-NALKSTGD 269
I L ET L V QG K ++ L +AL+S D
Sbjct: 1630 EIQLGHSNRQMAETQKHLRTV--QGQLKDSQLHLDDALRSNED 1670
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 55.1 bits (131), Expect = 3e-07
Identities = 72/460 (15%), Positives = 163/460 (35%), Gaps = 21/460 (4%)
Query: 321 NTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTP 380
++ D +S D++ + G+ + +S SS +++ S++ + D
Sbjct: 831 DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSN---- 886
Query: 381 LEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQEL 440
E SN D N +++ + + + S +S D+ + +
Sbjct: 887 -ESSNSSDSSDSSNSSDS-------DSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938
Query: 441 ETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAG 500
S+ S + +N + ++S++ ++ + + + D S +
Sbjct: 939 SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSS 998
Query: 501 TEGNCQEATGPS-TVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPV 559
N +++ S + D+ N D S ++ DSS + + +
Sbjct: 999 DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058
Query: 560 PVETLKDVKKEL-TYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENV 618
D + ++D S+ E + S ++ +++ +++SS++
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1118
Query: 619 DCPENPKIKLDGKLDQEGDDVQTAAE--EVLADGDTLDFED--DTVQSSGPRAGGEELDE 674
D N D + D +++ + D+ D D D+ SS + D
Sbjct: 1119 DS-SNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177
Query: 675 GVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHE--SPSQDISDACEAESTERCEMSEHP 732
+ D++ ++ SS + S+ +D + S S D SD+ ++ + S
Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS 1237
Query: 733 SQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGN 772
S + + SNS ++ D S N ES ++ GN
Sbjct: 1238 SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGN 1277
Score = 52.0 bits (123), Expect = 2e-06
Identities = 74/506 (14%), Positives = 169/506 (33%), Gaps = 19/506 (3%)
Query: 297 TEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSS 356
+E + D+ D D + +N++ SS + + + + + S SS
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSD 688
Query: 357 LPENTVQVESNEVMGAPDDRTRTPLEPSNCW----SDLDGGNHTENVGEAAVTQVEEQAG 412
+++ S+E + D + S+ SD D N +++ + + + +
Sbjct: 689 SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSD 748
Query: 413 TVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPA---HSTE 469
+ S S D+ D + S+ S + +N + + +S++
Sbjct: 749 SSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808
Query: 470 VGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEE 529
+ + + + D S + + +++ S D+ N D
Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSS 868
Query: 530 KSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEE-EQVK 588
S + DSS N+ + + ++D S + E
Sbjct: 869 DSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSN 928
Query: 589 STDRKSAVEAQN--EVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEV 646
S+D ++ ++ N + +++ +++SS + D N D D ++
Sbjct: 929 SSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDS-SNSSDSSDSNSSDSSDSSNSSDSSD 987
Query: 647 LADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPE 706
+D D+ SS + D + D++ ++ SS + S+ +D +
Sbjct: 988 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047
Query: 707 --------HESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPG 758
+ S S D SD+ ++ + S S++ + SNS ++ D S
Sbjct: 1048 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSD 1107
Query: 759 HFNPESREDTRGGNEKGKSKEDCTMS 784
+ D+ + S + S
Sbjct: 1108 SSDSSDSSDSSDSSNSSDSSDSSDSS 1133
Score = 51.6 bits (122), Expect = 3e-06
Identities = 55/315 (17%), Positives = 118/315 (37%), Gaps = 19/315 (6%)
Query: 473 DHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSD 532
D N E + R + ++ + GN ++ G D+ + D SD
Sbjct: 476 DANSESDNNSSSRGDASYNSD----ESKDNGNGSDSKGAEDDDSDSTS------DTNNSD 525
Query: 533 QQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDR 592
G + + K+ K K S + ++D S+ S+D
Sbjct: 526 SNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDS 585
Query: 593 KSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQ---EGDDVQTAAEEVLAD 649
S+ + ++ +++ +++SS++ D ++ D K D E D + ++ +D
Sbjct: 586 DSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSS-DSKSDSSKSESDSSDSDSKSDSSD 644
Query: 650 GDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHES 709
++ D D++ SS D + D++ ++ SS + S+ +D + S
Sbjct: 645 SNSSDSSDNS-DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSD----SSNSS 699
Query: 710 PSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTR 769
S D SD+ +++S++ + S S + S+S ++ + S N D+
Sbjct: 700 ESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 759
Query: 770 GGNEKGKSKEDCTMS 784
+ S + S
Sbjct: 760 DSSNSSDSSDSSDSS 774
Score = 47.8 bits (112), Expect = 4e-05
Identities = 72/558 (12%), Positives = 186/558 (33%), Gaps = 22/558 (3%)
Query: 232 NSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKR 291
+S+ + + ++SD+ ++ + + + + D + +S+ + N ++
Sbjct: 680 SSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSN 739
Query: 292 EILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQI 351
+ + D D ++ D S D++ + + + S
Sbjct: 740 SSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN-----SSDSNDSSNSSDS 794
Query: 352 LESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENV-----GEAAVTQ 406
+SS+ +++ +S++ + D + + SN D N +++ + + +
Sbjct: 795 SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSD 854
Query: 407 VEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAH 466
++ + S S D+ D E S+ S ++ ++++
Sbjct: 855 SSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDS 914
Query: 467 STEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEP 526
S + E + + S + N +++ S ++ D
Sbjct: 915 SDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSS 974
Query: 527 DEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQ 586
D S ++ DSS + + D + ++D S +
Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD-----SSNSSDSSNSSDSSN 1029
Query: 587 VKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEV 646
+ S ++ +++ ++ SS++ D ++ D + D ++E
Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS----DSSDSSDSSDSSDSSES- 1084
Query: 647 LADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPE 706
+D D+ SS + D + D++ ++ SS + S+ +D +
Sbjct: 1085 -SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143
Query: 707 HESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESRE 766
S S + SD+ ++ + S S + + SNS ++ D S +
Sbjct: 1144 -SSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1202
Query: 767 DTRGGNEKGKSKEDCTMS 784
D+ ++ S + S
Sbjct: 1203 DSSDSSDSSDSSDSSDSS 1220
Score = 47.0 bits (110), Expect = 7e-05
Identities = 106/599 (17%), Positives = 212/599 (35%), Gaps = 65/599 (10%)
Query: 237 TNGETSDTLNN--VGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREIL 294
TNG T N VG G E++ ++ G G + + ++EI+ N + E
Sbjct: 154 TNGNTDKNTQNGDVGDAGHN----EDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEG- 208
Query: 295 HNTEKEQHTEDTVKDCVDIEVFP-----AGENTEDQKSSEDTAPFLGTLAGATYEEQVQS 349
+ +E + EV P AG + D S + A E++
Sbjct: 209 NTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAG 268
Query: 350 QILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNC--WSDLDGGN--HTENVGEAAVT 405
+SS N + + + G DD + + S+ + D +G H E G+
Sbjct: 269 NGKDSS----NNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSK 324
Query: 406 QVEEQAGTVASCPLGHSDDT--VYHDDKCMVE--VPQELET-STGHSLEKEFTNQEAAEP 460
E AG +DT + H + VE + +E ET + G S +K + +
Sbjct: 325 SEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSG 384
Query: 461 KEVPAHSTEVGRDHNEEEGEETGLRDEKPIKT-------EVPG-----------SPAGTE 502
G + E++G+ + + +KT E PG S G++
Sbjct: 385 NRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSD 444
Query: 503 GNCQ------------EATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKK 550
N + P++ D N D + S +G+A +S + N
Sbjct: 445 SNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNG 504
Query: 551 KNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKI 610
+ K ++ D + N + + ++ + + + + ++ +++
Sbjct: 505 SDSKGAEDDDSDSTSDTNN--SDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSD 562
Query: 611 AAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFED-----DTVQSSGP 665
+++SS++ N D D + + + D+ D D D+ SS
Sbjct: 563 SSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 622
Query: 666 RAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTER 725
++ + + + ++K D + +S + D+ + + S S D SD+ ++ S+
Sbjct: 623 KSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSD 682
Query: 726 CEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGNEKGKSKEDCTMS 784
S + S + + SNS E+ D S + +S ++ S + S
Sbjct: 683 ---SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS 738
Score = 43.9 bits (102), Expect = 6e-04
Identities = 56/369 (15%), Positives = 130/369 (35%), Gaps = 15/369 (4%)
Query: 424 DTVYHDDKCMV-EVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEET 482
D+ DDK M + P + S G+ ++ ++ + +S E +D+ +
Sbjct: 451 DSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDE-SKDNGNGSDSKG 509
Query: 483 GLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQ 542
D+ ++ S + GN + D+ D + D S ++ DSS
Sbjct: 510 AEDDDSDSTSDTNNSDSNGNGNNGNDDNDKS-DSGKGKSDSSDSDSSDSSNSSDSSDSSD 568
Query: 543 KKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEE----EQVKSTDRKS---- 594
+ + + S D + ++D S+ + + S+D KS
Sbjct: 569 SDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSK 628
Query: 595 --AVEAQNEVTENPKQKIAAESSENVDCPE--NPKIKLDGKLDQEGDDVQTAAEEVLADG 650
+ + ++ + +++SS+N D + N D + D ++++ +
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSD 688
Query: 651 DTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESP 710
+ + S + + D + D++ + + S S D+ + S
Sbjct: 689 SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSD 748
Query: 711 SQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDTRG 770
S + SD+ ++ + S S + + SNS +++D S N ++
Sbjct: 749 SSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808
Query: 771 GNEKGKSKE 779
++ S +
Sbjct: 809 SSDSSDSSD 817
Score = 43.5 bits (101), Expect = 8e-04
Identities = 72/560 (12%), Positives = 195/560 (34%), Gaps = 25/560 (4%)
Query: 232 NSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKR 291
NS+ NG + N+ G K + ++ S+ +S+ + +
Sbjct: 523 NSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDS-------- 574
Query: 292 EILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQI 351
N+ + + D+ D D + +++ SS+ + + + + + + S
Sbjct: 575 ----NSSSDSDSSDS--DSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSK 628
Query: 352 LESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQA 411
ES S ++ S+ D + + + SN + D + +++ ++ + +
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSS-DSSNSSNSSDSSDSSDSSDSSSSSDSSNSS 687
Query: 412 GTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVG 471
+ S +S ++ D + ++S +S + + +N + + S++
Sbjct: 688 DSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSS 747
Query: 472 RDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKS 531
N + ++ ++ S ++ + + S+ + + D S
Sbjct: 748 DSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSD-SSNSSDSSNS 806
Query: 532 DQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTD 591
++ DSS + N + S + + +D + S+D
Sbjct: 807 SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866
Query: 592 RKSAVEAQN-----EVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEV 646
+ ++ N + +++ + +++SS++ + ++ D + + E
Sbjct: 867 SSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSES 926
Query: 647 LADGDTLDFED--DTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTL 704
D + D ++ SS D + D++ ++ S+ ++ S D+ +
Sbjct: 927 SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSD--SSDSSNSSD 984
Query: 705 PEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPES 764
S S D SD+ ++ ++ S S + + SNS ++ + S +
Sbjct: 985 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSD 1044
Query: 765 REDTRGGNEKGKSKEDCTMS 784
D+ ++ S + S
Sbjct: 1045 SSDSSDSSDSSNSSDSSDSS 1064
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 54.7 bits (130), Expect = 3e-07
Identities = 147/693 (21%), Positives = 273/693 (39%), Gaps = 95/693 (13%)
Query: 7 AQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRNTS 66
A E++ AQK EAR R +AE E ++K +E+ +EE SR
Sbjct: 411 AAFEELEKALSTAQKTEEAR----RKLKAEMDE-QIKTIEKTSEEERISLQQELSRVKQE 465
Query: 67 ASDEDERMS---VGSRGSLRVEE--RPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSG 121
D ++ S + L +E R E++ T+K +L + S
Sbjct: 466 VVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEY--- 522
Query: 122 DTSISIDTEASIREIKDSLAEVE-EKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEE 180
+ I E +E ++SLA E E KKA+++ ++ N+ + + +T + +LELE
Sbjct: 523 ---LKISQE---KEQQESLALEELELQKKAILTESE--NKLRDLQQEAETYRTRILELES 574
Query: 181 QLAESRRQYEEKNKEF----EREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIA 236
L +S ++ + ++K+ E EK+ H+ K+ M+EKH +E+
Sbjct: 575 SLEKSLQENKNQSKDLAVHLEAEKNKHN-------------KEITVMVEKH----KTELE 617
Query: 237 TNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKN-EIVANVGKREILH 295
+ D L Q + + E+ L+ + + E +K+ EI+ E+
Sbjct: 618 SLKHQQDALWTEKLQVLKQQYQTEMEKLREKCE----QEKETLLKDKEIIFQAHIEEMNE 673
Query: 296 NTEKEQHTEDTVKDCVDIE---VFPAGENTEDQKS--SEDTAPFLGTLAGATYEEQVQSQ 350
T ++ + T + + E V A E++ S + T L E++ Q
Sbjct: 674 KTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQ 733
Query: 351 ILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDL-DGGNHTENV------GEAA 403
S + E+ V ++ E D + L L + H EN+ E
Sbjct: 734 QQVDSIIKEHEVSIQRTE-KALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGE 792
Query: 404 VTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEV 463
+ Q + S + T ++++ + L+ T L + + A+ K+V
Sbjct: 793 LQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDV 852
Query: 464 ----PAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNE 519
AH +V + E + + + + T+V S QE T V+ +N
Sbjct: 853 CTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENM 912
Query: 520 PLDMKEPDEEKSDQQGEALDSSQK-------------KTKNKKKKNKKKKSPVPVETLK- 565
L M+E +++ + + L + + K + KK + K+K+ ETLK
Sbjct: 913 ILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKK 972
Query: 566 -------DVKKELTYQNTDLSEIKEEEQVKSTDRKSA-----VEAQNEVTENPKQKIAAE 613
+KKEL +LS+ +++ K + A +A + + N K++I E
Sbjct: 973 KLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQI--E 1030
Query: 614 SSENVDCPE-NPKIKL-DGKLDQEGDDVQTAAE 644
S V E N I + + KL+Q+ +++Q E
Sbjct: 1031 SLTEVHRRELNDVISIWEKKLNQQAEELQEIHE 1063
Score = 37.7 bits (86), Expect = 0.041
Identities = 95/525 (18%), Positives = 207/525 (39%), Gaps = 63/525 (12%)
Query: 140 LAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDML-LELEEQLAESRRQYEEKNKEFER 198
L + + + + + +L+ E + Q D +K L +++EQ ++Q + KE E
Sbjct: 686 LESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEV 745
Query: 199 E-KHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSDTLNNVG-----YQG 252
+ L+ Q +++ LK+R++ L++H + + A + L +Q
Sbjct: 746 SIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQS 805
Query: 253 PTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVD 312
T E+ A + + ++E + ++ + E ++ T D
Sbjct: 806 YQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQ-----VAEVEAQKKDVCTELDAHK 860
Query: 313 IEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQS--QILESSSLPENTVQVESNEVM 370
I+V + E Q S E++V+S Q+ ES N Q ++ +++
Sbjct: 861 IQVQDLMQQLEKQNSE--------------MEQKVKSLTQVYESKLEDGNKEQEQTKQIL 906
Query: 371 GAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDD 430
+E N + G E +E + + L +T + +
Sbjct: 907 ----------VEKENMILQMREGQKKEIEILTQKLSAKEDSIHI----LNEEYETKFKNQ 952
Query: 431 KCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPI 490
+ +E ++ +L+K+ +QEA KE+ + E+ + E++ L +
Sbjct: 953 EKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQ--KEKQFNAKMLEMAQAN 1010
Query: 491 KTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSS---QKKTKN 547
+ + + E N +E T + E D+ E+K +QQ E L Q + K
Sbjct: 1011 SAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKE 1070
Query: 548 KKKKNKKKKSPVPVETLKDVKKELTY-------QNTDLSEIKEEEQVKSTDRKSAVEAQN 600
++ K+K + +++ KE+T+ Q+T L+E++E+ + KS S + +
Sbjct: 1071 QEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDET 1130
Query: 601 EVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEE 645
++ + E ++ N +K + L ++ +++ AEE
Sbjct: 1131 KLKAH---------LEKLEVDLNKSLKENTFLQEQLVELKMLAEE 1166
Score = 35.0 bits (79), Expect = 0.27
Identities = 110/549 (20%), Positives = 195/549 (35%), Gaps = 76/549 (13%)
Query: 122 DTSISIDTEA-----SIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLL 176
D S +DT + ++ ++ D + E KKA Q N Q++
Sbjct: 1416 DLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAY 1475
Query: 177 ELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIA 236
E +EQ+ + + +++NK F+ L+ + + K ++++E LE L S+ A
Sbjct: 1476 EKDEQINLLKEELDQQNKRFD-------CLKGEMEDDKSKMEKKESNLETE---LKSQTA 1525
Query: 237 TNGETSD--------------TLNNVGYQGPT--KMTKEELNALKSTGDGTLGRASEVEV 280
E D L N Q K ++L + G+ R E E
Sbjct: 1526 RIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEE 1585
Query: 281 K-----NEIVA-----NVGKREILHNTEKEQHTEDTVKDCVD-IEVFPAGENTE-DQKSS 328
K N++ + K+E+ H + E+ +K D +E A + E +K+
Sbjct: 1586 KILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAE 1645
Query: 329 EDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQVESNE---------VMGAPDDRTRT 379
+ A L E++ Q + S L E +++ E + ++ T
Sbjct: 1646 QKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSET 1705
Query: 380 PLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQE 439
+ P + + E + V + E+ +V L +K + V QE
Sbjct: 1706 LIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEK-------EKLLQRVGQE 1758
Query: 440 LETSTGHSLEKEFTNQE---AAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPG 496
E + E QE E E H + H +EE EE + + V
Sbjct: 1759 KEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHV-- 1816
Query: 497 SPAGTEGNCQEATGPSTV-DTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKK 555
G + N Q V D + L KE + +Q+ + LDS + K + ++
Sbjct: 1817 EKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEE 1876
Query: 556 KSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKS----TDRKSAVEAQNE-------VTE 604
+ + + + + T+L E EE+ KS S +EAQ+ E
Sbjct: 1877 LTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAE 1936
Query: 605 NPKQKIAAE 613
KQK+ E
Sbjct: 1937 REKQKLGKE 1945
Score = 30.0 bits (66), Expect = 8.6
Identities = 44/214 (20%), Positives = 83/214 (38%), Gaps = 29/214 (13%)
Query: 543 KKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEV 602
+ KN ++ ++ K V ET + + + L E+KEEE + R + Q E
Sbjct: 349 RDAKNLIEQLEQDKGMVIAETKRQMHETL--------EMKEEEIAQLRSRIKQMTTQGEE 400
Query: 603 TENPKQKIAAESSENVD-------CPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDF 655
K+K + E ++ E + KL ++D++ ++ +EE
Sbjct: 401 LREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEE---------- 450
Query: 656 EDDTVQSSGPRAGGEELD---EGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQ 712
E ++Q R E +D + + AK+ + A + E + E E Q
Sbjct: 451 ERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQ 510
Query: 713 DISDACEAESTERCEMSEHPSQTVRKALDSNSLE 746
+ A E +E ++S+ Q AL+ L+
Sbjct: 511 -MKVALEKSQSEYLKISQEKEQQESLALEELELQ 543
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 54.7 bits (130), Expect = 3e-07
Identities = 73/309 (23%), Positives = 124/309 (40%), Gaps = 51/309 (16%)
Query: 429 DDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEV-----PAHSTE--VGRDHNEEEGEE 481
+ C E +++E G E T AA+ E+ PA T+ G+ NE E
Sbjct: 8 ESDCSAEAREKMEQKEGKLSEDGTTVSPAADNPEMSGGGAPAEETKGTAGKAINEGPPTE 67
Query: 482 TGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSS 541
+G +++ P + G A +G EA G DE K + Q EA
Sbjct: 68 SGKQEKAPAED---GMSAELQG---EANGL---------------DEVKVESQREAGGKE 106
Query: 542 QKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNE 601
+ + KK+ +K+++ V + + K+E SE KE E+ +ST + ++ +
Sbjct: 107 DAEAELKKEDGEKEETTVGSQEMTGRKEETK------SEPKEAEEKEST-----LASEKQ 155
Query: 602 VTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQ 661
E + K ES + D N + K + K E +D +TA++E G + + +
Sbjct: 156 KAEEKEAK--PESGQKADA--NDRDKPEPKATVEEEDAKTASQE--ETGQRKECSTEPKE 209
Query: 662 SSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAE 721
+ E + V +D AK + P EP ++ + E ++ DA EAE
Sbjct: 210 KATDEEAKAESQKAVVEDEAKAE------PKEPDGKEEAKHGAKEEADAKEEAEDAEEAE 263
Query: 722 STERCEMSE 730
E E
Sbjct: 264 PGSPSEEQE 272
Score = 52.4 bits (124), Expect = 2e-06
Identities = 67/297 (22%), Positives = 115/297 (38%), Gaps = 26/297 (8%)
Query: 437 PQELETSTGHSLEKEFTNQEAAEPKEVPAH---STEVGRDHN-------EEEGEETGLRD 486
P E T E E+ + ++ PA S E+ + N E + E G D
Sbjct: 48 PAEETKGTAGKAINEGPPTESGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKED 107
Query: 487 EKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTK 546
+ + G T QE TG +T++EP + +E + + ++ +A + K
Sbjct: 108 AEAELKKEDGEKEETTVGSQEMTGRKE-ETKSEPKEAEEKESTLASEKQKAEEKEAKPES 166
Query: 547 NKKKKNKKKKSPVPVETLK--DVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTE 604
+K + P P T++ D K + E E + K+TD ++ E+Q V E
Sbjct: 167 GQKADANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVE 226
Query: 605 NPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQSSG 664
+ + E + K + D K +E +D + A ++ D E + +G
Sbjct: 227 DEAKAEPKEPDGKEEAKHGAKEEADAK--EEAEDAEEAEPGSPSEEQEQDVEKEPEGGAG 284
Query: 665 P-RAGGEELDEGVAKD--NAKIDG-------ATQSSPAEPKSEDADRCTLPEHESPS 711
+ EE E + N DG + Q+SP+ +S +D P ESPS
Sbjct: 285 VIPSSPEEWPESPTGEGHNLSTDGLGPDCVASGQTSPSASESSPSDVPQSPP-ESPS 340
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 54.3 bits (129), Expect = 4e-07
Identities = 145/737 (19%), Positives = 274/737 (37%), Gaps = 91/737 (12%)
Query: 10 REIDCLSPEAQKLAEARLAAKR-------AARAEAREIRMKELERQQKEEDSERYSRRSR 62
RE+ E +L R+A +R AAR R R + L ++Q+EE + + +
Sbjct: 8 RELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVE 67
Query: 63 RNTSASDEDERMSVGSRGS--------------LRVEERPEKDFTEKGSRNMPGLSAATL 108
N S DE + + R EER +K E R T
Sbjct: 68 VNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITD 127
Query: 109 ASLGGTSSRRGSGDTSISIDTEASIR-EIKDSLAEVEE------KYKKAMVSNAQLDNEK 161
ASL SRR DT+ + TE + E + E+EE Y+K +A+ + ++
Sbjct: 128 ASLS-LPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKE 186
Query: 162 TNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQRE 221
+ + K + E E EEK E + E S+ Q + E KQ E
Sbjct: 187 DKEKEEEEEEKPKRGSIGENQVEV--MVEEKTTESQEETVVMSLKNGQISS--EEPKQEE 242
Query: 222 EMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVK 281
E + + EI+ + + + ++ EE +K+ D + ++
Sbjct: 243 EREQG-----SDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIAD-ERARIE 296
Query: 282 NEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGA 341
E A +RE E+E+ E+ + + + E+++++E+ A
Sbjct: 297 AEEKAAAQERERREAEERERMREEEKRAAEERQRI----KEEEKRAAEERQRIKEEEKRA 352
Query: 342 TYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGE 401
E Q + + ++ + E E + + LE T+ GE
Sbjct: 353 AEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKK-----HAMQETKIKGE 407
Query: 402 AAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEV--PQELETSTGHSLEKEFTNQEAAE 459
++E + ++ +DK V Q E T ++E ++
Sbjct: 408 KVEQKIEGK----------WVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPT 457
Query: 460 PKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAG--------TEGNCQEATGP 511
K+ ++ +D +E E D K TEV TE G
Sbjct: 458 FKKEEIKDEKIKKDKEPKE-EVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGR 516
Query: 512 STVDTQNEPLDMKEPDEEKSDQQGEALDSSQKK---TKNKKKKNKKKKSPVPVETLKDVK 568
++VDT KE + + G+ L+ +++ T++++ + K+K L+++K
Sbjct: 517 ASVDT-------KEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELK 569
Query: 569 KELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKL 628
K+ + L E ++ + + DRK E + + ++ AE++E + K+
Sbjct: 570 KKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAE-----KRQKMPE 624
Query: 629 DGKLDQEGD-DVQTAAEEVLADGDTLDFEDDTVQ-SSGPRAGGE-----ELDEGVAKDNA 681
DG D + T L + +F + +VQ SSG ++ + ++D + + +
Sbjct: 625 DGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTS 684
Query: 682 KIDGATQSSPAEPKSED 698
I+G + P +P + D
Sbjct: 685 AIEGTKSAKPTKPAASD 701
Score = 40.4 bits (93), Expect = 0.006
Identities = 89/511 (17%), Positives = 186/511 (36%), Gaps = 59/511 (11%)
Query: 184 ESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSD 243
E RR+ + +E R + Q + +EA ++R + + E + G+ +D
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTD 64
Query: 244 TLN-NVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQH 302
+ N P + K + GD + + E ++ + E+++
Sbjct: 65 QVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREER----RQKRLQEALERQKE 120
Query: 303 TEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTV 362
+ T+ D A + ++ DTA E ++ E S +
Sbjct: 121 FDPTITD--------ASLSLPSRRMQNDTA------------ENETTEKEEKSESRQERY 160
Query: 363 QVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHS 422
++E E T T N W D + + E EE+ +G +
Sbjct: 161 EIEETE--------TVTKSYQKNDWRDAEENKKEDKEKE------EEEEEKPKRGSIGEN 206
Query: 423 DDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEET 482
V ++K + ET + +++E + +E S E+ EE ++
Sbjct: 207 QVEVMVEEKT---TESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKE 263
Query: 483 GLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQ 542
E+ E + + A + ++ + + + E + ++ E + +
Sbjct: 264 RAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQER--ERREAEERERMREEE 321
Query: 543 KKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEV 602
K+ ++++ K+++ E + +K+E + IKEEE+ + +R+ A + E
Sbjct: 322 KRAAEERQRIKEEEKRAAEERQR-IKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEK 380
Query: 603 TENPKQKIAAESSENVDCPENPKI-------KLDGKLDQE----GDDVQTAAEEVLAD-- 649
+ +QK + E + KI K++GK E D +QTA + +
Sbjct: 381 AKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEK 440
Query: 650 GDTLDFEDDTVQSSGPRAGGEEL-DEGVAKD 679
G + + + +Q P EE+ DE + KD
Sbjct: 441 GTKVQAKREKLQEDKPTFKKEEIKDEKIKKD 471
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 53.5 bits (127), Expect = 7e-07
Identities = 115/563 (20%), Positives = 202/563 (35%), Gaps = 98/563 (17%)
Query: 2 TSPAAAQSREIDCLSPEAQKLAEARLAAKRAAR------------AEAREIRMKE--LER 47
TSP + S + D S + K E++ K R +E E+R +E L+
Sbjct: 1729 TSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKE 1788
Query: 48 QQKEEDSERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDFT--------EKGSRN 99
Q+K+ + E+ R+S S D+DE LR + R E+ T E S
Sbjct: 1789 QEKQREIEQQQRKSSSKKSKKDKDE---------LRAQRRRERPKTPPSNLSPIEDASPT 1839
Query: 100 MPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIK-DSLAEVEEKYKKAMVSNAQLD 158
AA + L R + S SI+++ EI + + EV++ YK +
Sbjct: 1840 EELRQAAEMEEL----HRSSCSEYSPSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSP 1895
Query: 159 NEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALK 218
++ + M + + K L+ E++ E K K F A
Sbjct: 1896 TDEQSIMQKEGSQK--ALKSAEEMYEEMMHKTHKYKAF------------------PAAN 1935
Query: 219 QREEMLEK---HGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRA 275
+R+E+ EK +G +L + DT N G +EE N GR
Sbjct: 1936 ERDEVFEKEPLYGGMLIEDYIYESLVEDTYNG-SVDGSLLTRQEEENGFMQ----QKGRE 1990
Query: 276 SEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAP-- 333
++ + +I + Q D K+ ++E + ED SS P
Sbjct: 1991 QKIRLSEQIY-----------EDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFIIPES 2039
Query: 334 ----FLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSD 389
LGT+ +T EE+ ++L++ + E ++ + ++ T+ P+ S
Sbjct: 2040 HEIVDLGTMVTSTEEER---KLLDADAAYEELMKRQQMQLTPG-SSPTQAPIGEDMTEST 2095
Query: 390 LDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLE 449
+D + ++V + +S L D V++ Q T +E
Sbjct: 2096 MDFDRMPDASLTSSVLSGASLTDSTSSATLSIPD----------VKITQHFST---EEIE 2142
Query: 450 KEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEAT 509
E+ E +E+ AH + + E + + P T S T+ + T
Sbjct: 2143 DEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITT 2202
Query: 510 GPSTVDTQNEPLDMKEPDEEKSD 532
S EP+DM E+ +
Sbjct: 2203 LDSITTVYTEPVDMITKFEDSEE 2225
Score = 31.6 bits (70), Expect = 3.0
Identities = 92/526 (17%), Positives = 185/526 (35%), Gaps = 55/526 (10%)
Query: 235 IATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREIL 294
++ G +SD +++ + P+ + +E + LK + + S +++ + +L
Sbjct: 1360 LSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKL--ESTVL 1417
Query: 295 HNTEKEQHT---EDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQI 351
E + T E + K EV P E K E T TL EE+++
Sbjct: 1418 SILEAQASTLADEKSEKKTQPHEVSP-----EQPKDQEKTQSLSETLEITISEEEIK--- 1469
Query: 352 LESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQA 411
ES ++T + +S + + + D + + + + E E+ + V ++
Sbjct: 1470 -ESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRK 1528
Query: 412 GTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVG 471
+ +G S Y E S G E++F ++ E S
Sbjct: 1529 RRTS---VGSSSSDEYKQ-----------EDSQGSGEEEDFIRKQIIEMSADEDASGSED 1574
Query: 472 RDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKS 531
+ + +E E K E G T G + T S+ + +E
Sbjct: 1575 DEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDD 1634
Query: 532 DQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTD 591
+ E+ + ++TK+++ + + K ++ T + +E +++ D
Sbjct: 1635 EAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFD 1694
Query: 592 RKSAVEAQNEVTENPKQKIAAESSENVDCPE-------NPKIKLDGKLD-----QEGDDV 639
+ +E ++ +T++P+ + E S ++ LD D ++G+
Sbjct: 1695 EEPELEMES-LTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESK 1753
Query: 640 QTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDA 699
Q G L +D+ + R E L E + + SS K +D
Sbjct: 1754 QQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDE 1813
Query: 700 DRC--------TLP------EHESPSQDISDACEAESTERCEMSEH 731
R T P E SP++++ A E E R SE+
Sbjct: 1814 LRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEY 1859
Score = 30.8 bits (68), Expect = 5.1
Identities = 108/579 (18%), Positives = 209/579 (36%), Gaps = 92/579 (15%)
Query: 45 LERQQKEEDSERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLS 104
+E + E+S R+ R + +S DE S+GS E+DF K M
Sbjct: 1513 VEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGS-----GEEEDFIRKQIIEM---- 1563
Query: 105 AATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNF 164
D S S D E ++K+ + E + K+ ++ K
Sbjct: 1564 -------------SADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRR 1610
Query: 165 MYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEML 224
+ + + ++E ++E ++ F+ + ++ E K ++ EE++
Sbjct: 1611 LTRKSS-----TSIDEDAGRRHSWHDEDDEAFDESP------ELKYRETKS--QESEELV 1657
Query: 225 EKHG--------IILNSEIAT--NGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGR 274
G I LNS IA + E+S ++ + ++ E L S D + G
Sbjct: 1658 VTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLT--DSPEDRSRGE 1715
Query: 275 ASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKS-SEDTAP 333
S + + E + K GE+ + +K+ P
Sbjct: 1716 GSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKK----------GESKQQRKARHRPHGP 1765
Query: 334 FLGTLAGATYEEQV------------QSQILESSSLPENTVQVESNEVMGAPDDRTRTPL 381
L T+ ++ EE++ Q +I + + + + + A R R
Sbjct: 1766 LLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKT 1825
Query: 382 EPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYH-DDKCMVEVPQEL 440
PSN S ++ + TE + +AA + ++ P SD + + ++EV +
Sbjct: 1826 PPSNL-SPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQKVY 1884
Query: 441 ETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEET---------GLRDEKPIK 491
+ T SL T++++ KE + + + EE +T RDE K
Sbjct: 1885 KLPTAVSLYSP-TDEQSIMQKEGSQKALKSAEEMYEEMMHKTHKYKAFPAANERDEVFEK 1943
Query: 492 TEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKK 551
+ G E E+ DT N + D +Q E Q+K + +K +
Sbjct: 1944 EPLYGGML-IEDYIYESL---VEDTYNGSV-----DGSLLTRQEEENGFMQQKGREQKIR 1994
Query: 552 NKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKST 590
++ P++ + D++KE Y+ L + +E + S+
Sbjct: 1995 LSEQIYEDPMQKITDLQKEF-YELESLHSVVPQEDIVSS 2032
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 53.5 bits (127), Expect = 7e-07
Identities = 115/563 (20%), Positives = 202/563 (35%), Gaps = 98/563 (17%)
Query: 2 TSPAAAQSREIDCLSPEAQKLAEARLAAKRAAR------------AEAREIRMKE--LER 47
TSP + S + D S + K E++ K R +E E+R +E L+
Sbjct: 1729 TSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKE 1788
Query: 48 QQKEEDSERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDFT--------EKGSRN 99
Q+K+ + E+ R+S S D+DE LR + R E+ T E S
Sbjct: 1789 QEKQREIEQQQRKSSSKKSKKDKDE---------LRAQRRRERPKTPPSNLSPIEDASPT 1839
Query: 100 MPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIK-DSLAEVEEKYKKAMVSNAQLD 158
AA + L R + S SI+++ EI + + EV++ YK +
Sbjct: 1840 EELRQAAEMEEL----HRSSCSEYSPSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSP 1895
Query: 159 NEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALK 218
++ + M + + K L+ E++ E K K F A
Sbjct: 1896 TDEQSIMQKEGSQK--ALKSAEEMYEEMMHKTHKYKAF------------------PAAN 1935
Query: 219 QREEMLEK---HGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRA 275
+R+E+ EK +G +L + DT N G +EE N GR
Sbjct: 1936 ERDEVFEKEPLYGGMLIEDYIYESLVEDTYNG-SVDGSLLTRQEEENGFMQ----QKGRE 1990
Query: 276 SEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAP-- 333
++ + +I + Q D K+ ++E + ED SS P
Sbjct: 1991 QKIRLSEQIY-----------EDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFIIPES 2039
Query: 334 ----FLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSD 389
LGT+ +T EE+ ++L++ + E ++ + ++ T+ P+ S
Sbjct: 2040 HEIVDLGTMVTSTEEER---KLLDADAAYEELMKRQQMQLTPG-SSPTQAPIGEDMTEST 2095
Query: 390 LDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLE 449
+D + ++V + +S L D V++ Q T +E
Sbjct: 2096 MDFDRMPDASLTSSVLSGASLTDSTSSATLSIPD----------VKITQHFST---EEIE 2142
Query: 450 KEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEAT 509
E+ E +E+ AH + + E + + P T S T+ + T
Sbjct: 2143 DEYVTDYTREIQEIIAHESLILTYSEPSESATSVPPSDTPSLTSSVSSVCTTDSSSPITT 2202
Query: 510 GPSTVDTQNEPLDMKEPDEEKSD 532
S EP+DM E+ +
Sbjct: 2203 LDSITTVYTEPVDMITKFEDSEE 2225
Score = 31.6 bits (70), Expect = 3.0
Identities = 92/526 (17%), Positives = 185/526 (35%), Gaps = 55/526 (10%)
Query: 235 IATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREIL 294
++ G +SD +++ + P+ + +E + LK + + S +++ + +L
Sbjct: 1360 LSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKL--ESTVL 1417
Query: 295 HNTEKEQHT---EDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQI 351
E + T E + K EV P E K E T TL EE+++
Sbjct: 1418 SILEAQASTLADEKSEKKTQPHEVSP-----EQPKDQEKTQSLSETLEITISEEEIK--- 1469
Query: 352 LESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQA 411
ES ++T + +S + + + D + + + + E E+ + V ++
Sbjct: 1470 -ESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRK 1528
Query: 412 GTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVG 471
+ +G S Y E S G E++F ++ E S
Sbjct: 1529 RRTS---VGSSSSDEYKQ-----------EDSQGSGEEEDFIRKQIIEMSADEDASGSED 1574
Query: 472 RDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKS 531
+ + +E E K E G T G + T S+ + +E
Sbjct: 1575 DEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDD 1634
Query: 532 DQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTD 591
+ E+ + ++TK+++ + + K ++ T + +E +++ D
Sbjct: 1635 EAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFD 1694
Query: 592 RKSAVEAQNEVTENPKQKIAAESSENVDCPE-------NPKIKLDGKLD-----QEGDDV 639
+ +E ++ +T++P+ + E S ++ LD D ++G+
Sbjct: 1695 EEPELEMES-LTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESK 1753
Query: 640 QTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDA 699
Q G L +D+ + R E L E + + SS K +D
Sbjct: 1754 QQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDE 1813
Query: 700 DRC--------TLP------EHESPSQDISDACEAESTERCEMSEH 731
R T P E SP++++ A E E R SE+
Sbjct: 1814 LRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEY 1859
Score = 30.8 bits (68), Expect = 5.1
Identities = 108/579 (18%), Positives = 209/579 (36%), Gaps = 92/579 (15%)
Query: 45 LERQQKEEDSERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLS 104
+E + E+S R+ R + +S DE S+GS E+DF K M
Sbjct: 1513 VEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGS-----GEEEDFIRKQIIEM---- 1563
Query: 105 AATLASLGGTSSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNF 164
D S S D E ++K+ + E + K+ ++ K
Sbjct: 1564 -------------SADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRR 1610
Query: 165 MYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEML 224
+ + + ++E ++E ++ F+ + ++ E K ++ EE++
Sbjct: 1611 LTRKSS-----TSIDEDAGRRHSWHDEDDEAFDESP------ELKYRETKS--QESEELV 1657
Query: 225 EKHG--------IILNSEIAT--NGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGR 274
G I LNS IA + E+S ++ + ++ E L S D + G
Sbjct: 1658 VTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLT--DSPEDRSRGE 1715
Query: 275 ASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKS-SEDTAP 333
S + + E + K GE+ + +K+ P
Sbjct: 1716 GSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKK----------GESKQQRKARHRPHGP 1765
Query: 334 FLGTLAGATYEEQV------------QSQILESSSLPENTVQVESNEVMGAPDDRTRTPL 381
L T+ ++ EE++ Q +I + + + + + A R R
Sbjct: 1766 LLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKT 1825
Query: 382 EPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYH-DDKCMVEVPQEL 440
PSN S ++ + TE + +AA + ++ P SD + + ++EV +
Sbjct: 1826 PPSNL-SPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQKVY 1884
Query: 441 ETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEET---------GLRDEKPIK 491
+ T SL T++++ KE + + + EE +T RDE K
Sbjct: 1885 KLPTAVSLYSP-TDEQSIMQKEGSQKALKSAEEMYEEMMHKTHKYKAFPAANERDEVFEK 1943
Query: 492 TEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKK 551
+ G E E+ DT N + D +Q E Q+K + +K +
Sbjct: 1944 EPLYGGML-IEDYIYESL---VEDTYNGSV-----DGSLLTRQEEENGFMQQKGREQKIR 1994
Query: 552 NKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKST 590
++ P++ + D++KE Y+ L + +E + S+
Sbjct: 1995 LSEQIYEDPMQKITDLQKEF-YELESLHSVVPQEDIVSS 2032
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 53.1 bits (126), Expect = 1e-06
Identities = 59/252 (23%), Positives = 109/252 (43%), Gaps = 21/252 (8%)
Query: 433 MVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKT 492
+V V E++ S K T + E + + + V E EE + K +
Sbjct: 27 LVPVTPEVKPKRTSSSRKMKTKSDMME-ENIDTSAQAVAETKQEAVVEEDYNENAKNGEA 85
Query: 493 EVPGSPAGT-------EGNCQEATGPS-------TVDTQNEPLDMKEPDEEKSDQQGEA- 537
++ +PA E N ++AT + +NE D KE +E++++++GEA
Sbjct: 86 KITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAG 145
Query: 538 -LDSSQK-KTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSA 595
D +K + K+ KN +K E K E N + + K E++ + DRK
Sbjct: 146 KEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKET 205
Query: 596 VEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAE-EVLADGDTLD 654
+ + E+ K+K + ++V E+ K + DGK D+ G++ + E E L + +
Sbjct: 206 GDGKE--NEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGK 263
Query: 655 FEDDTVQSSGPR 666
ED+ + G +
Sbjct: 264 EEDEIKEDDGKK 275
Score = 34.3 bits (77), Expect = 0.46
Identities = 36/196 (18%), Positives = 79/196 (40%), Gaps = 19/196 (9%)
Query: 593 KSAVEAQNEVTENPKQKIAAESSENVDCPENPKIK---------LDGKLDQEGDDVQTAA 643
K Q ++ + PK++ A S+ V P P++K + K D +++ T+A
Sbjct: 3 KRKAAGQGDMRQEPKRRSARLSAMLV--PVTPEVKPKRTSSSRKMKTKSDMMEENIDTSA 60
Query: 644 EEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCT 703
+ V E+D +++ + G ++ E A + ++ E EDA
Sbjct: 61 QAVAETKQEAVVEEDYNENA--KNGEAKITEAPASEKEIVE------VKEENIEDATEKG 112
Query: 704 LPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPE 763
+ E+ + ++ + E + + + +E + ++ D E+ G E G E
Sbjct: 113 GEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKE 172
Query: 764 SREDTRGGNEKGKSKE 779
+ +G + KG ++
Sbjct: 173 KEDGKKGEDGKGNGED 188
Score = 32.7 bits (73), Expect = 1.3
Identities = 53/239 (22%), Positives = 94/239 (39%), Gaps = 35/239 (14%)
Query: 511 PSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQK---KTK---------NKKKKNKKKK-- 556
P T + + + + KSD E +D+S + +TK N+ KN + K
Sbjct: 29 PVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKIT 88
Query: 557 -SPVPVETLKDVKKELTYQNTD---------LSEIK-EEEQVKSTD---RKSAVEAQNEV 602
+P + + +VK+E T+ +E+K EEE K + + EA E
Sbjct: 89 EAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKED 148
Query: 603 TENPKQKIAAESSENVDCPENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQS 662
+ ++ E + E+ K K DGK +G+D + E+ G+ E+D ++
Sbjct: 149 KDEKGEEDGKEDKNGNEKGEDAKEKEDGK---KGEDGKGNGEDGKEKGEDEKEEEDRKET 205
Query: 663 SGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAE 721
G+E ++G K + K + E + ED E ++ D E E
Sbjct: 206 ----GDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEE 260
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 53.1 bits (126), Expect = 1e-06
Identities = 141/752 (18%), Positives = 282/752 (37%), Gaps = 94/752 (12%)
Query: 5 AAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSRRN 64
A Q E C EA+ E A + + ++ELE Q +EE+S R + +
Sbjct: 908 AKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKV 967
Query: 65 TSAS-----DEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRG 119
T+ + +E++ + L E++ +D + + N+ +
Sbjct: 968 TTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLT------------EEEEKS 1015
Query: 120 SGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELE 179
+ EA I ++++ L E++ ++ + +L+ + T+ Q+ L+ + EL+
Sbjct: 1016 KSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELK 1075
Query: 180 EQLAESRRQYEEKNKEFEREKHAHSI-------LQFQFAEVKEALKQR---EEMLEKHGI 229
QLA+ + + E E ++ L+ Q +E++E L+ EK
Sbjct: 1076 MQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKR 1135
Query: 230 ILNSEI-ATNGETSDTLNNVGYQGPTKMTKE-ELNALKSTGDGTLGRASEVEVK------ 281
L E+ A E DTL++ Q + +E E+N LK T + + E +++
Sbjct: 1136 DLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEE-AKTHEAQIQEMRQKH 1194
Query: 282 NEIVANVGK-----REILHNTEKEQHTEDTVKD--CVDIEVFPAGENTEDQKSSEDTAPF 334
++ V + + + + N EK + T + + +++V G+ + K + A
Sbjct: 1195 SQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQL 1254
Query: 335 LGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGN 394
E+V++++ + + +QVE + V G + + +S L+ +
Sbjct: 1255 QELQVKFNEGERVRTELADKVT----KLQVELDNVTGLLSQSDSKSSKLTKDFSALE--S 1308
Query: 395 HTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTN 454
++ E + Q E + S L + D+K E E H+LEK+
Sbjct: 1309 QLQDTQE--LLQEENRQKLSLSTKLKQVE-----DEKNSFREQLEEEEEAKHNLEKQIAT 1361
Query: 455 QEAAEPKEVPAHSTEVGRDHNEEEGEE------TGLRDEKPIKTEVPGSPAGTEGNCQEA 508
A VG EE + GL K T+ Q+
Sbjct: 1362 LHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQE 1421
Query: 509 TGPSTVDTQNE-----PLDMKEPD------EEKSDQQGEALDSSQKKTKNKKKKNKKKKS 557
VD ++ L+ K+ EEK+ A + + + + ++K+ K
Sbjct: 1422 LDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSL 1481
Query: 558 PVPVETLKDVKKELTYQN-------TDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKI 610
+E + K EL N DL K++ + + + A + E K ++
Sbjct: 1482 ARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQL 1541
Query: 611 AAESSENVDCPENPKIKLDGKL---------DQEGDDVQTAAEEVLADGDT----LDFED 657
E + + E+ K++L+ L D +G D Q+ ++ + ED
Sbjct: 1542 -EELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELED 1600
Query: 658 DTVQSSGPRAGGEELDEGVAKDNAKIDGATQS 689
+ Q S A ++L+ + A ID A ++
Sbjct: 1601 ERKQRSMAVAARKKLEMDLKDLEAHIDSANKN 1632
Score = 35.4 bits (80), Expect = 0.21
Identities = 61/323 (18%), Positives = 129/323 (39%), Gaps = 47/323 (14%)
Query: 5 AAAQSREIDCLSPEAQKLAEARLAAKRAARAEARE----IRMKELERQQKEEDSERYSRR 60
A Q R++ + + + A++ A+A+E ++ E E Q +E+ R
Sbjct: 1636 AIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERA 1695
Query: 61 SRRNTSASDE--DERMSVGSRGSLRVEERPEKDFT----EKGSRNMPGLSAATLASLGGT 114
R+ DE DE + +G+L +EE+ + E+ G + L
Sbjct: 1696 KRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKA 1755
Query: 115 SSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNE-KTNFMYQVDTLKD 173
+ + +T ++++ + ++ +++ ++E + K+ V +++ K+ + + L+
Sbjct: 1756 NLQIDQINTDLNLE-RSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEA 1814
Query: 174 MLLELEEQLAESRRQYEEKNKEFER-EKHAHSIL--------------------QFQFAE 212
+ +LEEQL ++ + K+ R EK +L + +
Sbjct: 1815 KIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQ 1874
Query: 213 VKEALKQREEMLEKHGII---LNSEIATNGETSDTLNNVGYQGPTKMTKEEL-------N 262
+K L++ EE ++ L E+ ET+D +N K+ + +L
Sbjct: 1875 LKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGDLPFVVPRRM 1934
Query: 263 ALKSTGDGT----LGRASEVEVK 281
A K GDG+ G+A E K
Sbjct: 1935 ARKGAGDGSDEEVDGKADGAEAK 1957
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 53.1 bits (126), Expect = 1e-06
Identities = 111/562 (19%), Positives = 207/562 (36%), Gaps = 90/562 (16%)
Query: 78 SRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIK 137
+R R E PE D +K P L ++ +A+ + R D ++ + R I
Sbjct: 92 TRRESRQESDPEDDDVKK-----PALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIF 146
Query: 138 DSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFE 197
L +K+K+ S + +K +++ +LE Q E R+Q E + +E
Sbjct: 147 GLLMGTLQKFKQE--STVATERQKRR--------QEIEQKLEVQAEEERKQVENERRELF 196
Query: 198 REKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNG------------------ 239
E+ A + + E K L Q +E +H + I T
Sbjct: 197 EERRAKQ-TELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKL 255
Query: 240 -ETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVAN---VGKREILH 295
E S N ++G E++N +++ R S E ++++V N ++E
Sbjct: 256 IEESQRKMNALFEGRRIEFAEQINKMEARP----RRQSMKEKEHQVVRNEEQKAEQEEGK 311
Query: 296 NTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESS 355
++E+ E+T D+E+ AGE E + + + A EE+ Q Q +E
Sbjct: 312 VAQREEELEETGNQHNDVEIEEAGEEEEKE------IAIVHSDAEKEQEEEEQKQEMEVK 365
Query: 356 SLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVA 415
E V+ + P++ +D ENV Q + V
Sbjct: 366 MEEETEVRESEKQQDSQPEE-------------VMDVLEMVENVKHVIADQEVMETNRVE 412
Query: 416 SCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHN 475
S P E E S E EF + E K + V
Sbjct: 413 SVE------------------PSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDM 454
Query: 476 EEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQG 535
E+E EE ++ +P V ++ Q + +Q++P+ +P + D
Sbjct: 455 EKESEEKEEKESEPQPEPVAQPQPQSQPQLQ-------LQSQSQPVLQSQPPSQPEDLSL 507
Query: 536 EALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSA 595
L + + T+ + ++K PVE++K + + T E K + + +S +S
Sbjct: 508 AVLQPTPQVTQEQGHLLPERKD-FPVESVKLTEVPVEPVLTVHPESKSKTKTRS---RSR 563
Query: 596 VEAQNEVTENPKQKIAAESSEN 617
A+N+ +++ + ++ SS +
Sbjct: 564 GRARNKTSKSRSRSSSSSSSSS 585
Score = 32.0 bits (71), Expect = 2.3
Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 4/79 (5%)
Query: 58 SRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTS-S 116
SR S +TS+S E S G RG R +R + ++ R+ GL + +S GG+S
Sbjct: 618 SRDSSSSTSSSSESRSRSRG-RGHNR--DRKHRRSVDRKRRDTSGLERSHKSSKGGSSRD 674
Query: 117 RRGSGDTSISIDTEASIRE 135
+GS D + D + SI E
Sbjct: 675 TKGSKDKNSRSDRKRSISE 693
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 52.8 bits (125), Expect = 1e-06
Identities = 147/786 (18%), Positives = 286/786 (36%), Gaps = 102/786 (12%)
Query: 3 SPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRRSR 62
SPA QS+ SPE++ + R ++ + E +E E +++EE+ E
Sbjct: 1035 SPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEE 1094
Query: 63 RNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGD 122
+E+E ++ P + T+ S + L G RR
Sbjct: 1095 EEEEEEEEEE----------NIQSSPPR-LTKPQSVAIKRKRPFVLKKKRGRKRRR---- 1139
Query: 123 TSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKT-NFMYQVDTLKDMLLELEEQ 181
I++ + I ++ + E + + E T + D K +L + +
Sbjct: 1140 ----INSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQH 1195
Query: 182 LAESRRQYEEK----NKEFEREKHAHSILQFQFAEVKEALKQREEMLE---------KHG 228
+RQ EE+ N F+ + + + +KE K E L+ K G
Sbjct: 1196 QPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRG 1255
Query: 229 IILNSEIATNGETSDTLNNVGYQGP-TKMTKEELNALKSTGDGTLGRASEVEVK-NEIVA 286
+ S+ N E Y P T M +E ++ + + G+ S ++ E V
Sbjct: 1256 L---SKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVK 1312
Query: 287 NVGKREILHNTEKEQHTEDTVKDCV-------DIEVFPAGENTEDQKSSEDTAPFLG--T 337
G+ + + + T V D + P E E+++ E+ G
Sbjct: 1313 ETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEE 1372
Query: 338 LAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTE 397
G E+ + PE + + E + + ++ EPS+ D D + +
Sbjct: 1373 EGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHN-EDHDADDEDD 1431
Query: 398 NVGEAAVTQVEE-------------QAGTVASCPLGHSDDTVYHDDKCMVEVPQELETST 444
+ E+A + EE + + GHS+ V D C V++ T++
Sbjct: 1432 SHMESAEVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMD--CGVDL-----TAS 1484
Query: 445 GHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGN 504
+S KE A +P+ VP E E+ ++ ++ K + TE EGN
Sbjct: 1485 CNSEPKEL----AGDPEAVPESDEE---PPPGEQAQKQDQKNSKEVDTEF------KEGN 1531
Query: 505 CQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALD---SSQKKTKNKKKKNKKKKSPVPV 561
P+T++ +E + + ++S +Q + +Q+ ++ + + +SP
Sbjct: 1532 ------PATMEIDSETVQAVQSLTQESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIA 1585
Query: 562 ETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTE-NPKQK-IAAESSENVD 619
TL D ++ + V+S + S +N + +P Q I+ S +N++
Sbjct: 1586 TTLDDCQQSDHSSPVSSVHSHPGQSVRSVNSPSVPALENSYAQISPDQSAISVPSLQNME 1645
Query: 620 CPENPKIKLDGKLDQEGDDVQTAAEEV-LADGDTLDFEDDTVQSS---GPRAGGEELDEG 675
+P + + D V + ++ + T ++E+ + S G G
Sbjct: 1646 --TSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNGSSQNS 1703
Query: 676 VAKDNAKIDGATQSSPA--EPKSEDADRCTLPEHESPSQDISDACEAESTERCEMSEHPS 733
+ N TQSS A + S + C++ + S S C +S + C + PS
Sbjct: 1704 CSYSNLTSSSLTQSSCAVTQQMSNISGSCSMLQQTSISS--PPTCSVKSPQGCVVERPPS 1761
Query: 734 QTVRKA 739
+ + A
Sbjct: 1762 SSQQLA 1767
Score = 45.1 bits (105), Expect = 3e-04
Identities = 60/351 (17%), Positives = 142/351 (40%), Gaps = 47/351 (13%)
Query: 438 QELETSTGHSLEKEFTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGS 497
Q E TG L + EP E + E ++ +E + + +R E+ +K E +
Sbjct: 1261 QNKERKTGFKLNLYTPPETPMEPDEQV--TVEEQKETSEGKTSPSPIRIEEEVK-ETGEA 1317
Query: 498 PAGTEGNCQEAT----GPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNK 553
E N +E T P+T + D+ +P+EE+ +++ E + +++ + ++
Sbjct: 1318 LLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGN 1377
Query: 554 KKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAE 613
+K P ++ + + E++ + D + + + E+ + D + + ++ + + +
Sbjct: 1378 VEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESA 1437
Query: 614 SSENVDCP-----------------------ENPKIKLDGKLDQEGDDVQTAAEEVLADG 650
E + P NP++ +D +D + +E+ D
Sbjct: 1438 EVEKEELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTA-SCNSEPKELAGDP 1496
Query: 651 DTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHESP 710
+ + D+ GE+ + K++ ++D T+ P + + D T+ +S
Sbjct: 1497 EAVPESDEEPPP------GEQAQKQDQKNSKEVD--TEFKEGNPATMEIDSETVQAVQSL 1548
Query: 711 SQDISDACE-----AESTERCEMSEH---PSQTVRKALDSNSLENDDLSAP 753
+Q+ S+ + AE+ E C ++ Q+ + A + + D S+P
Sbjct: 1549 TQESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSP 1599
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 52.4 bits (124), Expect = 2e-06
Identities = 142/840 (16%), Positives = 300/840 (35%), Gaps = 128/840 (15%)
Query: 5 AAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEED--SERYSRRSR 62
+A + R++ + +A LA + +E R + E+ KE ++ ++R
Sbjct: 347 SATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKAR 406
Query: 63 RNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGD 122
+ +++ S L R + D +E +N+P T S GG + +
Sbjct: 407 KGEKPCALEKKDISKSEAKL---SRKQVD-SEHMHQNVPTEEQRTNKSTGGEHKKSDRKE 462
Query: 123 ------TSISIDTEASIREIKDSLAE-VEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDML 175
+ S D + I + S+ E + E + AM + +D++ ++
Sbjct: 463 EPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSS 522
Query: 176 LELEEQLAESRRQYEEKNK-EFEREKHAH------SILQFQFAEVKEALKQRE------- 221
++L ++R + K + +E + S + A+ +E + ++
Sbjct: 523 VKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGL 582
Query: 222 -EMLEKHGI---------ILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGT 271
LEK G+ ++ +E++ E SD + + E N + S D
Sbjct: 583 NPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSD-- 640
Query: 272 LGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDT 331
E NE V K + + ++++ D+ D P + +E + D+
Sbjct: 641 -------EECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDS 693
Query: 332 APFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLD 391
L L + S + + + N + + DD+ + + S SD D
Sbjct: 694 DEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFD 753
Query: 392 GGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKE 451
G++A + + ++ ++ +D + E+ + + +K
Sbjct: 754 -----TKKGKSAKSSI------ISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR 802
Query: 452 FTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGP 511
N + + E HS + G D+ + K +KT GS E + T
Sbjct: 803 IPNTKDFDSSEDEKHSKK-GMDN----------QGHKNLKTSQEGSSDDAERKQERETFS 851
Query: 512 S---TVDTQNEPLDMKE--PDEEKSDQQGEALDSSQKK--------------TKNKKKKN 552
S TVD +++++ P ++++ + +D K TK K K
Sbjct: 852 SAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHL 911
Query: 553 KKKKSPVPVETLKDVKKELTY--QNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKI 610
K K + L D+ ++ Q+ + SE +++ K T+ K + +Q+
Sbjct: 912 KTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQY 971
Query: 611 AAESSENVDCPENPKI----------------------KLDGKLDQEGDDVQTAAEEVLA 648
+ S PE +I K+ K ++ D++ AE+
Sbjct: 972 ESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTG 1031
Query: 649 DGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHE 708
GD+ D +D +G A G E K K+ G + + S D ++ ++ E
Sbjct: 1032 KGDSCDSSEDKKSKNG--AYGRE------KKRCKLLGKSSRKRQDCSSSDTEKYSMKEDG 1083
Query: 709 SPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDT 768
S D + +R E+ E + + ++ ++ +++ S+ E N + ++ T
Sbjct: 1084 CNSSD-------KRLKRIELRERRNLSSKR--NTKEIQSGSSSSDAEESSEDNKKKKQRT 1134
Score = 52.0 bits (123), Expect = 2e-06
Identities = 116/617 (18%), Positives = 236/617 (38%), Gaps = 90/617 (14%)
Query: 10 REIDCLSPEAQKLAEARLAAKRAARAEAREIR-------MKELERQQKEEDSERYSRRSR 62
+E S E +K+AE + +K ++++ K L++ Q +E SE ++S+
Sbjct: 889 KEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSK 948
Query: 63 RNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGD 122
+ T +E ++ S + +++E++ E + G+ +P G + G+ D
Sbjct: 949 KGT---EEKKKPSDFKKKVIKMEQQYES--SSDGTEKLPEREEICHFPKGIKQIKNGTTD 1003
Query: 123 ---TSISIDTEASIREIKDSLAEVEEKYK-KAMVSNAQLDNEKTNFMYQVDTLKDMLLEL 178
S I + S + KD L++ EK K ++ D + N Y + + LL
Sbjct: 1004 GEKKSKKIRDKTSKK--KDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLG- 1060
Query: 179 EEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA-LKQREEMLEKHGIILNSEIAT 237
SR++ + + + E+ +K L++R + K EI +
Sbjct: 1061 ----KSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRN---TKEIQS 1113
Query: 238 NGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNT 297
+SD A +S+ D + K ++ KR L +
Sbjct: 1114 GSSSSD-------------------AEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTS 1154
Query: 298 EKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSL 357
K + + T DIE +DQ S + + +EQ + E+ L
Sbjct: 1155 TKRKQADITSSSSSDIE-------DDDQNS----------IGEGSSDEQKIKPVTENLVL 1197
Query: 358 PENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASC 417
+T +S+ D + P D D + + + + +EE ++S
Sbjct: 1198 SSHTGFCQSS------GDEALSKSVPVTVDDDDDDNDPENRIAKKML--LEEIKANLSSD 1249
Query: 418 PLGHSDDTVYHDDKCM----VEVPQELETSTGHSLEKEFTNQEAAEPK---EVPAHSTEV 470
G SDD K E P + E + E + ++E+ +P+ + H V
Sbjct: 1250 EDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTV 1309
Query: 471 GRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEK 530
+ EE ++T ++ K +K N ++ + + D+ + + E E
Sbjct: 1310 SDGESGEE-KKTKPKEHKEVKGR----------NRRKVSSEDSEDSDFQESGVSEEVSES 1358
Query: 531 SDQQGEALDSSQK-KTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKS 589
D+Q S++K + + ++ K+KK ++ +D E + + E KEEE+ +
Sbjct: 1359 EDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEE 1418
Query: 590 TDRKSAVEAQNEVTENP 606
+ + E +N+ +++P
Sbjct: 1419 EEEEEEEEDENDDSKSP 1435
Score = 42.4 bits (98), Expect = 0.002
Identities = 146/807 (18%), Positives = 294/807 (36%), Gaps = 103/807 (12%)
Query: 4 PAAAQSREIDCLSPEAQKLA----EARLAAKRAARAEAREIR-----MKELERQQKEEDS 54
P + QS +D S + LA +R++ ++ + EI + +L+ Q ++D
Sbjct: 679 PKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDK 738
Query: 55 ERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGT 114
+ R+S +TS SD D + ++ S+ +++ + T+ S N + S+
Sbjct: 739 GKRKRKS--STSGSDFDTKKGKSAKSSIISKKKRQ---TQSESSNYDSELEKEIKSM--- 790
Query: 115 SSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDM 174
S+ G+ T T+ I KD + +EK+ K + N N KT+ Q + D
Sbjct: 791 -SKIGAART-----TKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTS---QEGSSDDA 841
Query: 175 LLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSE 234
+ E + S +K+ + Q A +++ K + E
Sbjct: 842 ERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGV----DKLSGKEQSFTSLE 897
Query: 235 IATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREIL 294
+ ET + ++ TK K+ + L + L + E + K++
Sbjct: 898 VRKVAETKEKSKHL----KTKTCKKVQDGLSDIAEKFLKKDQSDETSED-----DKKQSK 948
Query: 295 HNTEKEQHTEDTVKDCVDIE--VFPAGENTEDQKSSEDTAPFLGTLA----GATYEEQVQ 348
TE+++ D K + +E + + TE E+ F + G T E+
Sbjct: 949 KGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKS 1008
Query: 349 SQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVE 408
+I + +S ++ + + + G D + + S + + +G+++ + +
Sbjct: 1009 KKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQD 1068
Query: 409 EQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHST 468
+ + +D DK + + +E +L + +E +
Sbjct: 1069 CSSSDTEKYSM--KEDGCNSSDKRL----KRIELRERRNLSSKRNTKEIQSGSS--SSDA 1120
Query: 469 EVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDE 528
E + N+++ + T + + I E + T ++A S+ + E D E
Sbjct: 1121 EESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGE 1180
Query: 529 EKSDQQ-------GEALDSSQKKTKNKKKKNKKKKSPVPVET----------------LK 565
SD+Q L S ++ + K PV V+ L+
Sbjct: 1181 GSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLE 1240
Query: 566 DVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPK 625
++K L+ S+ + EE K T +++ +N E K ++ +ES + + + P+
Sbjct: 1241 EIKANLSSDEDGSSDDEPEEGKKRTGKQNE---ENPGDEEAKNQVNSESDSDSEESKKPR 1297
Query: 626 IK----------LDGKLDQEGDDVQTAAEEVLADG----DTLDFEDDTVQSSGPRAGGEE 671
+ DG+ +E +EV + D ED Q SG EE
Sbjct: 1298 YRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGV---SEE 1354
Query: 672 LDEGVAKDNAKIDGATQSSPAEPK---SEDADRCTLPEHESPSQDISDACEAESTERCEM 728
+ E + + A ++ E + + R + E S + E E E+ E
Sbjct: 1355 VSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEE 1414
Query: 729 SEHPSQTVRKALDSNSLENDDLSAPGR 755
E + + D ENDD +PG+
Sbjct: 1415 EEEEEEEEEEEED----ENDDSKSPGK 1437
Score = 38.5 bits (88), Expect = 0.024
Identities = 144/764 (18%), Positives = 276/764 (36%), Gaps = 118/764 (15%)
Query: 72 ERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEA 131
+++ V S S +V E + +K S N G S G+ + S + +
Sbjct: 258 KKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSA-LIVPKEMIK 316
Query: 132 SIREIKDSLAEVEEKYKKAM--------VSNAQLDNEKTNFMYQVDTLKDMLLELEEQLA 183
+++ ++ A + Y K + +S+A + F + +K L LEE L
Sbjct: 317 KAKKLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLN 376
Query: 184 ESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSD 243
R + NK E+ H ++ +F E K ++ LEK I SE + + D
Sbjct: 377 SEFRAMDAVNK--EKNTKEHKVIDAKF-ETKARKGEKPCALEKKD-ISKSEAKLSRKQVD 432
Query: 244 TLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHT 303
+ ++ PT EE KSTG G + + K E + E + +E
Sbjct: 433 S-EHMHQNVPT----EEQRTNKSTG----GEHKKSDRKEE-----PQYEPANTSEDLDMD 478
Query: 304 EDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQ 363
+V V ++F EN E + + G + T +E S + + S +N
Sbjct: 479 IVSVPSSVPEDIF---ENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGG 535
Query: 364 VESNE---------VMGAPDDRTRTPLEPSNCW---SDLDG------------------G 393
++S V P + +P++ ++C D DG
Sbjct: 536 IKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQEN 595
Query: 394 NHTENVGEAAVTQVEEQAG-----TVASCPLGHSDD----TVYHDDKCMVEVPQELETST 444
+ E++ E V+ + E++ V + PL + T D++C V ++ + S
Sbjct: 596 SDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSV 655
Query: 445 GHSLEKEFTNQEAA----EPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAG 500
+ + + ++A +P ++P D N + E + K + S +
Sbjct: 656 PVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAIL--KEVSRMSHSSSSD 713
Query: 501 TEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVP 560
T+ N + T ++ L + K D+ SS + KK K KS +
Sbjct: 714 TDIN--------EIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSII 765
Query: 561 VETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDC 620
+ + + E + +++L E+++KS + A + N K + D
Sbjct: 766 SKKKRQTQSESSNYDSEL-----EKEIKSMSKIGAARTTKKRIPNTK---------DFDS 811
Query: 621 PENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDN 680
E+ K G +D +G ++E +D E +T S+ EG +
Sbjct: 812 SEDEKHSKKG-MDNQGHKNLKTSQEGSSDDAERKQERETFSSA----------EGTVDKD 860
Query: 681 AKI----DGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTERCEMSEH-PSQT 735
I D + A ++ D+ + E S ++ E + E S+H ++T
Sbjct: 861 TTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETK-----EKSKHLKTKT 915
Query: 736 VRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGNEKGKSKE 779
+K D S + + + ++ +G EK K +
Sbjct: 916 CKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSD 959
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 52.4 bits (124), Expect = 2e-06
Identities = 142/840 (16%), Positives = 300/840 (35%), Gaps = 128/840 (15%)
Query: 5 AAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEED--SERYSRRSR 62
+A + R++ + +A LA + +E R + E+ KE ++ ++R
Sbjct: 385 SATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKAR 444
Query: 63 RNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGD 122
+ +++ S L R + D +E +N+P T S GG + +
Sbjct: 445 KGEKPCALEKKDISKSEAKL---SRKQVD-SEHMHQNVPTEEQRTNKSTGGEHKKSDRKE 500
Query: 123 ------TSISIDTEASIREIKDSLAE-VEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDML 175
+ S D + I + S+ E + E + AM + +D++ ++
Sbjct: 501 EPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSS 560
Query: 176 LELEEQLAESRRQYEEKNK-EFEREKHAH------SILQFQFAEVKEALKQRE------- 221
++L ++R + K + +E + S + A+ +E + ++
Sbjct: 561 VKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGL 620
Query: 222 -EMLEKHGI---------ILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGT 271
LEK G+ ++ +E++ E SD + + E N + S D
Sbjct: 621 NPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSD-- 678
Query: 272 LGRASEVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDT 331
E NE V K + + ++++ D+ D P + +E + D+
Sbjct: 679 -------EECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDS 731
Query: 332 APFLGTLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLD 391
L L + S + + + N + + DD+ + + S SD D
Sbjct: 732 DEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFD 791
Query: 392 GGNHTENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKE 451
G++A + + ++ ++ +D + E+ + + +K
Sbjct: 792 -----TKKGKSAKSSI------ISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR 840
Query: 452 FTNQEAAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGP 511
N + + E HS + G D+ + K +KT GS E + T
Sbjct: 841 IPNTKDFDSSEDEKHSKK-GMDN----------QGHKNLKTSQEGSSDDAERKQERETFS 889
Query: 512 S---TVDTQNEPLDMKE--PDEEKSDQQGEALDSSQKK--------------TKNKKKKN 552
S TVD +++++ P ++++ + +D K TK K K
Sbjct: 890 SAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHL 949
Query: 553 KKKKSPVPVETLKDVKKELTY--QNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKI 610
K K + L D+ ++ Q+ + SE +++ K T+ K + +Q+
Sbjct: 950 KTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQY 1009
Query: 611 AAESSENVDCPENPKI----------------------KLDGKLDQEGDDVQTAAEEVLA 648
+ S PE +I K+ K ++ D++ AE+
Sbjct: 1010 ESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTG 1069
Query: 649 DGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKSEDADRCTLPEHE 708
GD+ D +D +G A G E K K+ G + + S D ++ ++ E
Sbjct: 1070 KGDSCDSSEDKKSKNG--AYGRE------KKRCKLLGKSSRKRQDCSSSDTEKYSMKEDG 1121
Query: 709 SPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGREPGHFNPESREDT 768
S D + +R E+ E + + ++ ++ +++ S+ E N + ++ T
Sbjct: 1122 CNSSD-------KRLKRIELRERRNLSSKR--NTKEIQSGSSSSDAEESSEDNKKKKQRT 1172
Score = 52.0 bits (123), Expect = 2e-06
Identities = 116/617 (18%), Positives = 236/617 (38%), Gaps = 90/617 (14%)
Query: 10 REIDCLSPEAQKLAEARLAAKRAARAEAREIR-------MKELERQQKEEDSERYSRRSR 62
+E S E +K+AE + +K ++++ K L++ Q +E SE ++S+
Sbjct: 927 KEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSK 986
Query: 63 RNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGD 122
+ T +E ++ S + +++E++ E + G+ +P G + G+ D
Sbjct: 987 KGT---EEKKKPSDFKKKVIKMEQQYES--SSDGTEKLPEREEICHFPKGIKQIKNGTTD 1041
Query: 123 ---TSISIDTEASIREIKDSLAEVEEKYK-KAMVSNAQLDNEKTNFMYQVDTLKDMLLEL 178
S I + S + KD L++ EK K ++ D + N Y + + LL
Sbjct: 1042 GEKKSKKIRDKTSKK--KDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLG- 1098
Query: 179 EEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA-LKQREEMLEKHGIILNSEIAT 237
SR++ + + + E+ +K L++R + K EI +
Sbjct: 1099 ----KSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRN---TKEIQS 1151
Query: 238 NGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNT 297
+SD A +S+ D + K ++ KR L +
Sbjct: 1152 GSSSSD-------------------AEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTS 1192
Query: 298 EKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSL 357
K + + T DIE +DQ S + + +EQ + E+ L
Sbjct: 1193 TKRKQADITSSSSSDIE-------DDDQNS----------IGEGSSDEQKIKPVTENLVL 1235
Query: 358 PENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVEEQAGTVASC 417
+T +S+ D + P D D + + + + +EE ++S
Sbjct: 1236 SSHTGFCQSS------GDEALSKSVPVTVDDDDDDNDPENRIAKKML--LEEIKANLSSD 1287
Query: 418 PLGHSDDTVYHDDKCM----VEVPQELETSTGHSLEKEFTNQEAAEPK---EVPAHSTEV 470
G SDD K E P + E + E + ++E+ +P+ + H V
Sbjct: 1288 EDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTV 1347
Query: 471 GRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDEEK 530
+ EE ++T ++ K +K N ++ + + D+ + + E E
Sbjct: 1348 SDGESGEE-KKTKPKEHKEVKGR----------NRRKVSSEDSEDSDFQESGVSEEVSES 1396
Query: 531 SDQQGEALDSSQK-KTKNKKKKNKKKKSPVPVETLKDVKKELTYQNTDLSEIKEEEQVKS 589
D+Q S++K + + ++ K+KK ++ +D E + + E KEEE+ +
Sbjct: 1397 EDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEE 1456
Query: 590 TDRKSAVEAQNEVTENP 606
+ + E +N+ +++P
Sbjct: 1457 EEEEEEEEDENDDSKSP 1473
Score = 42.4 bits (98), Expect = 0.002
Identities = 146/807 (18%), Positives = 294/807 (36%), Gaps = 103/807 (12%)
Query: 4 PAAAQSREIDCLSPEAQKLA----EARLAAKRAARAEAREIR-----MKELERQQKEEDS 54
P + QS +D S + LA +R++ ++ + EI + +L+ Q ++D
Sbjct: 717 PKSKQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDK 776
Query: 55 ERYSRRSRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGT 114
+ R+S +TS SD D + ++ S+ +++ + T+ S N + S+
Sbjct: 777 GKRKRKS--STSGSDFDTKKGKSAKSSIISKKKRQ---TQSESSNYDSELEKEIKSM--- 828
Query: 115 SSRRGSGDTSISIDTEASIREIKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDM 174
S+ G+ T T+ I KD + +EK+ K + N N KT+ Q + D
Sbjct: 829 -SKIGAART-----TKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTS---QEGSSDDA 879
Query: 175 LLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSE 234
+ E + S +K+ + Q A +++ K + E
Sbjct: 880 ERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGV----DKLSGKEQSFTSLE 935
Query: 235 IATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREIL 294
+ ET + ++ TK K+ + L + L + E + K++
Sbjct: 936 VRKVAETKEKSKHL----KTKTCKKVQDGLSDIAEKFLKKDQSDETSED-----DKKQSK 986
Query: 295 HNTEKEQHTEDTVKDCVDIE--VFPAGENTEDQKSSEDTAPFLGTLA----GATYEEQVQ 348
TE+++ D K + +E + + TE E+ F + G T E+
Sbjct: 987 KGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKS 1046
Query: 349 SQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHTENVGEAAVTQVE 408
+I + +S ++ + + + G D + + S + + +G+++ + +
Sbjct: 1047 KKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQD 1106
Query: 409 EQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQEAAEPKEVPAHST 468
+ + +D DK + + +E +L + +E +
Sbjct: 1107 CSSSDTEKYSM--KEDGCNSSDKRL----KRIELRERRNLSSKRNTKEIQSGSS--SSDA 1158
Query: 469 EVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDTQNEPLDMKEPDE 528
E + N+++ + T + + I E + T ++A S+ + E D E
Sbjct: 1159 EESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGE 1218
Query: 529 EKSDQQ-------GEALDSSQKKTKNKKKKNKKKKSPVPVET----------------LK 565
SD+Q L S ++ + K PV V+ L+
Sbjct: 1219 GSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLE 1278
Query: 566 DVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPK 625
++K L+ S+ + EE K T +++ +N E K ++ +ES + + + P+
Sbjct: 1279 EIKANLSSDEDGSSDDEPEEGKKRTGKQNE---ENPGDEEAKNQVNSESDSDSEESKKPR 1335
Query: 626 IK----------LDGKLDQEGDDVQTAAEEVLADG----DTLDFEDDTVQSSGPRAGGEE 671
+ DG+ +E +EV + D ED Q SG EE
Sbjct: 1336 YRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGV---SEE 1392
Query: 672 LDEGVAKDNAKIDGATQSSPAEPK---SEDADRCTLPEHESPSQDISDACEAESTERCEM 728
+ E + + A ++ E + + R + E S + E E E+ E
Sbjct: 1393 VSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEE 1452
Query: 729 SEHPSQTVRKALDSNSLENDDLSAPGR 755
E + + D ENDD +PG+
Sbjct: 1453 EEEEEEEEEEEED----ENDDSKSPGK 1475
Score = 38.5 bits (88), Expect = 0.024
Identities = 144/764 (18%), Positives = 276/764 (36%), Gaps = 118/764 (15%)
Query: 72 ERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEA 131
+++ V S S +V E + +K S N G S G+ + S + +
Sbjct: 296 KKIKVDSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSA-LIVPKEMIK 354
Query: 132 SIREIKDSLAEVEEKYKKAM--------VSNAQLDNEKTNFMYQVDTLKDMLLELEEQLA 183
+++ ++ A + Y K + +S+A + F + +K L LEE L
Sbjct: 355 KAKKLIETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLN 414
Query: 184 ESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEKHGIILNSEIATNGETSD 243
R + NK E+ H ++ +F E K ++ LEK I SE + + D
Sbjct: 415 SEFRAMDAVNK--EKNTKEHKVIDAKF-ETKARKGEKPCALEKKD-ISKSEAKLSRKQVD 470
Query: 244 TLNNVGYQGPTKMTKEELNALKSTGDGTLGRASEVEVKNEIVANVGKREILHNTEKEQHT 303
+ ++ PT EE KSTG G + + K E + E + +E
Sbjct: 471 S-EHMHQNVPT----EEQRTNKSTG----GEHKKSDRKEE-----PQYEPANTSEDLDMD 516
Query: 304 EDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLGTLAGATYEEQVQSQILESSSLPENTVQ 363
+V V ++F EN E + + G + T +E S + + S +N
Sbjct: 517 IVSVPSSVPEDIF---ENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNISSKDNRGG 573
Query: 364 VESNE---------VMGAPDDRTRTPLEPSNCW---SDLDG------------------G 393
++S V P + +P++ ++C D DG
Sbjct: 574 IKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLEKCGLGQEN 633
Query: 394 NHTENVGEAAVTQVEEQAG-----TVASCPLGHSDD----TVYHDDKCMVEVPQELETST 444
+ E++ E V+ + E++ V + PL + T D++C V ++ + S
Sbjct: 634 SDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETVKEKQKLSV 693
Query: 445 GHSLEKEFTNQEAA----EPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAG 500
+ + + ++A +P ++P D N + E + K + S +
Sbjct: 694 PVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAIL--KEVSRMSHSSSSD 751
Query: 501 TEGNCQEATGPSTVDTQNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVP 560
T+ N + T ++ L + K D+ SS + KK K KS +
Sbjct: 752 TDIN--------EIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSII 803
Query: 561 VETLKDVKKELTYQNTDLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDC 620
+ + + E + +++L E+++KS + A + N K + D
Sbjct: 804 SKKKRQTQSESSNYDSEL-----EKEIKSMSKIGAARTTKKRIPNTK---------DFDS 849
Query: 621 PENPKIKLDGKLDQEGDDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDN 680
E+ K G +D +G ++E +D E +T S+ EG +
Sbjct: 850 SEDEKHSKKG-MDNQGHKNLKTSQEGSSDDAERKQERETFSSA----------EGTVDKD 898
Query: 681 AKI----DGATQSSPAEPKSEDADRCTLPEHESPSQDISDACEAESTERCEMSEH-PSQT 735
I D + A ++ D+ + E S ++ E + E S+H ++T
Sbjct: 899 TTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETK-----EKSKHLKTKT 953
Query: 736 VRKALDSNSLENDDLSAPGREPGHFNPESREDTRGGNEKGKSKE 779
+K D S + + + ++ +G EK K +
Sbjct: 954 CKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSD 997
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.302 0.121 0.324
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,154,957
Number of Sequences: 37866
Number of extensions: 1558032
Number of successful extensions: 13618
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 248
Number of HSP's successfully gapped in prelim test: 993
Number of HSP's that attempted gapping in prelim test: 8013
Number of HSP's gapped (non-prelim): 4749
length of query: 784
length of database: 18,247,518
effective HSP length: 110
effective length of query: 674
effective length of database: 14,082,258
effective search space: 9491441892
effective search space used: 9491441892
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.