Guide to the Human Genome
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Search of human proteins with 21166382

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21166382 neurexin 2 isoform beta precursor [Homo sapiens]
         (666 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21166382 neurexin 2 isoform beta precursor [Homo sapiens]         1362   0.0  
gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]      1172   0.0  
gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]      1095   0.0  
gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]       439   e-123
gi|21070967 neurexin 1 isoform beta precursor [Homo sapiens]          419   e-117
gi|157427673 neurexin 3 isoform 3 precursor [Homo sapiens]            419   e-117
gi|41350305 neurexin 3 isoform 2 precursor [Homo sapiens]             370   e-102
gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]        366   e-101
gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens]             328   7e-90
gi|153792074 proline rich 12 [Homo sapiens]                            57   4e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    55   3e-07
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    54   5e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    54   5e-07
gi|38787970 tensin like C1 domain containing phosphatase isoform...    53   1e-06
gi|38787957 tensin like C1 domain containing phosphatase isoform...    53   1e-06
gi|38787941 tensin like C1 domain containing phosphatase isoform...    53   1e-06
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       52   1e-06
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       52   1e-06
gi|148536848 carboxyl ester lipase precursor [Homo sapiens]            51   3e-06
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]         50   5e-06
gi|116284392 mucin 2 precursor [Homo sapiens]                          50   7e-06
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p...    48   3e-05
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   48   3e-05
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   48   3e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   48   3e-05
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    48   3e-05
gi|116256464 hypothetical protein LOC343990 [Homo sapiens]             48   3e-05
gi|63025220 ring finger protein 215 [Homo sapiens]                     48   3e-05
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      47   4e-05
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       47   4e-05

>gi|21166382 neurexin 2 isoform beta precursor [Homo sapiens]
          Length = 666

 Score = 1362 bits (3525), Expect = 0.0
 Identities = 666/666 (100%), Positives = 666/666 (100%)

Query: 1   MPPGGSGPGGCPRRPPALAGPLPPPPPPPPPPLLPLLPLLLLLLLGAAEGARVSSSLSTT 60
           MPPGGSGPGGCPRRPPALAGPLPPPPPPPPPPLLPLLPLLLLLLLGAAEGARVSSSLSTT
Sbjct: 1   MPPGGSGPGGCPRRPPALAGPLPPPPPPPPPPLLPLLPLLLLLLLGAAEGARVSSSLSTT 60

Query: 61  HHVHHFHSKHGTVPIAINRMPFLTRGGHAGTTYIFGKGGALITYTWPPNDRPSTRMDRLA 120
           HHVHHFHSKHGTVPIAINRMPFLTRGGHAGTTYIFGKGGALITYTWPPNDRPSTRMDRLA
Sbjct: 61  HHVHHFHSKHGTVPIAINRMPFLTRGGHAGTTYIFGKGGALITYTWPPNDRPSTRMDRLA 120

Query: 121 VGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVGTDDITIDEPNAIVSDGKYH 180
           VGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVGTDDITIDEPNAIVSDGKYH
Sbjct: 121 VGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVGTDDITIDEPNAIVSDGKYH 180

Query: 181 VVRFTRSGGNATLQVDSWPVNERYPAGNFDNERLAIARQRIPYRLGRVVDEWLLDKGRQL 240
           VVRFTRSGGNATLQVDSWPVNERYPAGNFDNERLAIARQRIPYRLGRVVDEWLLDKGRQL
Sbjct: 181 VVRFTRSGGNATLQVDSWPVNERYPAGNFDNERLAIARQRIPYRLGRVVDEWLLDKGRQL 240

Query: 241 TIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGLKVLALAAESDPNVRTEGHLRLVGEGPSV 300
           TIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGLKVLALAAESDPNVRTEGHLRLVGEGPSV
Sbjct: 241 TIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGLKVLALAAESDPNVRTEGHLRLVGEGPSV 300

Query: 301 LLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSD 360
           LLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSD
Sbjct: 301 LLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSD 360

Query: 361 DEDLEECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPP 420
           DEDLEECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPP
Sbjct: 361 DEDLEECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPP 420

Query: 421 AARRPPSGGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTL 480
           AARRPPSGGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTL
Sbjct: 421 AARRPPSGGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTL 480

Query: 481 LSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPT 540
           LSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPT
Sbjct: 481 LSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPT 540

Query: 541 SFEPRRPPPLRPGVTSAPGFPHLPTANPTGPGERGPPGAVEVIRESSSTTGMVVGIVAAA 600
           SFEPRRPPPLRPGVTSAPGFPHLPTANPTGPGERGPPGAVEVIRESSSTTGMVVGIVAAA
Sbjct: 541 SFEPRRPPPLRPGVTSAPGFPHLPTANPTGPGERGPPGAVEVIRESSSTTGMVVGIVAAA 600

Query: 601 ALCILILLYAMYKYRNRDEGSYQVDQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKKNK 660
           ALCILILLYAMYKYRNRDEGSYQVDQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKKNK
Sbjct: 601 ALCILILLYAMYKYRNRDEGSYQVDQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKKNK 660

Query: 661 DKEYYV 666
           DKEYYV
Sbjct: 661 DKEYYV 666


>gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]
          Length = 1712

 Score = 1172 bits (3032), Expect = 0.0
 Identities = 577/577 (100%), Positives = 577/577 (100%)

Query: 90   GTTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI 149
            GTTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI
Sbjct: 1136 GTTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI 1195

Query: 150  DQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNF 209
            DQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNF
Sbjct: 1196 DQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNF 1255

Query: 210  DNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYY 269
            DNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYY
Sbjct: 1256 DNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYY 1315

Query: 270  NGLKVLALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATT 329
            NGLKVLALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATT
Sbjct: 1316 NGLKVLALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATT 1375

Query: 330  TTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGGELILPIITEDSLDPPP 389
            TTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGGELILPIITEDSLDPPP
Sbjct: 1376 TTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGGELILPIITEDSLDPPP 1435

Query: 390  VATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARRPPSGGPCQAERDDSDCEEPIEASGF 449
            VATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARRPPSGGPCQAERDDSDCEEPIEASGF
Sbjct: 1436 VATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARRPPSGGPCQAERDDSDCEEPIEASGF 1495

Query: 450  ASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSA 509
            ASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSA
Sbjct: 1496 ASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSA 1555

Query: 510  PAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEPRRPPPLRPGVTSAPGFPHLPTANPT 569
            PAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEPRRPPPLRPGVTSAPGFPHLPTANPT
Sbjct: 1556 PAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEPRRPPPLRPGVTSAPGFPHLPTANPT 1615

Query: 570  GPGERGPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDQSRN 629
            GPGERGPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDQSRN
Sbjct: 1616 GPGERGPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDQSRN 1675

Query: 630  YISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV 666
            YISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV
Sbjct: 1676 YISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV 1712



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 47/208 (22%), Positives = 82/208 (39%), Gaps = 31/208 (14%)

Query: 97  KGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGV 156
           KG     Y    N   S+  D + + F T QR+ +++    ++   DY+ L +  G V +
Sbjct: 293 KGNEFFCYDLSHNPIQSST-DEITLAFRTLQRNGLMLHTGKSA---DYVNLSLKSGAVWL 348

Query: 157 IFNVGTD--DITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAG------N 208
           + N+G+   +  ++  N   +D  +H VR TR              N R  AG      N
Sbjct: 349 VINLGSGAFEALVEPVNGKFNDNAWHDVRVTR--------------NLRQHAGIGHAMVN 394

Query: 209 FDNERLAIARQRIPYRLGRVVDEW-LLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGL 267
             +  + I+   I    G   +++ +L       I  S     + G      F G +  +
Sbjct: 395 KLHYLVTISVDGILTTTGYTQEDYTMLGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDV 454

Query: 268 YYNG----LKVLALAAESDPNVRTEGHL 291
            Y      L++  LA E DP ++ +G L
Sbjct: 455 VYKNNDFKLELSRLAKEGDPKMKLQGDL 482



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 18/75 (24%), Positives = 38/75 (50%)

Query: 123 FSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVV 182
           FS  +R+       S++   DY  + +  G + ++ ++G+  I +   +  V+DG++  V
Sbjct: 532 FSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSRKVNDGEWCHV 591

Query: 183 RFTRSGGNATLQVDS 197
            F R G   ++ V+S
Sbjct: 592 DFQRDGRKGSISVNS 606



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 1/78 (1%)

Query: 119 LAVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVGTDDITIDEPNAIVSDGK 178
           L+    T+   A+L+ +D   G  D+L+L +  G + + F +   +    + +  V+D +
Sbjct: 53  LSFSLRTNATRALLLYLDDG-GDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDR 111

Query: 179 YHVVRFTRSGGNATLQVD 196
           +H+V  TR      L VD
Sbjct: 112 WHMVLLTRDARRTALAVD 129


>gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]
          Length = 1642

 Score = 1095 bits (2833), Expect = 0.0
 Identities = 547/577 (94%), Positives = 547/577 (94%), Gaps = 30/577 (5%)

Query: 90   GTTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI 149
            GTTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI
Sbjct: 1096 GTTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI 1155

Query: 150  DQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNF 209
            DQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPA   
Sbjct: 1156 DQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPA--- 1212

Query: 210  DNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYY 269
                                       GRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYY
Sbjct: 1213 ---------------------------GRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYY 1245

Query: 270  NGLKVLALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATT 329
            NGLKVLALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATT
Sbjct: 1246 NGLKVLALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATT 1305

Query: 330  TTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGGELILPIITEDSLDPPP 389
            TTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGGELILPIITEDSLDPPP
Sbjct: 1306 TTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGGELILPIITEDSLDPPP 1365

Query: 390  VATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARRPPSGGPCQAERDDSDCEEPIEASGF 449
            VATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARRPPSGGPCQAERDDSDCEEPIEASGF
Sbjct: 1366 VATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARRPPSGGPCQAERDDSDCEEPIEASGF 1425

Query: 450  ASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSA 509
            ASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSA
Sbjct: 1426 ASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSA 1485

Query: 510  PAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEPRRPPPLRPGVTSAPGFPHLPTANPT 569
            PAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEPRRPPPLRPGVTSAPGFPHLPTANPT
Sbjct: 1486 PAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEPRRPPPLRPGVTSAPGFPHLPTANPT 1545

Query: 570  GPGERGPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDQSRN 629
            GPGERGPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDQSRN
Sbjct: 1546 GPGERGPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDQSRN 1605

Query: 630  YISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV 666
            YISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV
Sbjct: 1606 YISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV 1642



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 46/202 (22%), Positives = 81/202 (40%), Gaps = 26/202 (12%)

Query: 97  KGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGV 156
           KG     Y    N   S+  D + + F T QR+ +++    ++   DY+ L +  G V +
Sbjct: 269 KGNEFFCYDLSHNPIQSST-DEITLAFRTLQRNGLMLHTGKSA---DYVNLSLKSGAVWL 324

Query: 157 IFNVGTD--DITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNFDNERL 214
           + N+G+   +  ++  N   +D  +H VR TR              N R  AG   +  +
Sbjct: 325 VINLGSGAFEALVEPVNGKFNDNAWHDVRVTR--------------NLRQHAG-IGHAMV 369

Query: 215 AIARQRIPYRLGRVVDEW-LLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYNG-- 271
            I+   I    G   +++ +L       I  S     + G      F G +  + Y    
Sbjct: 370 TISVDGILTTTGYTQEDYTMLGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDVVYKNND 429

Query: 272 --LKVLALAAESDPNVRTEGHL 291
             L++  LA E DP ++ +G L
Sbjct: 430 FKLELSRLAKEGDPKMKLQGDL 451



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 34/156 (21%), Positives = 67/156 (42%), Gaps = 27/156 (17%)

Query: 127 QRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTR 186
           QR+  L+   ++    D L+L +D G + +  N+G    T+   + + +D ++H VR  R
Sbjct: 732 QRAYGLMMATTSRESADTLRLELDGGQMKLTVNLGKGPETLFAGHKL-NDNEWHTVRVVR 790

Query: 187 SGGNATLQVDSWPVNERYPAGNFDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQ 246
            G +  L VD+  V            ++A A  R+ +     ++  ++ + R +++  S 
Sbjct: 791 RGKSLQLSVDNVTV----------EGQMAGAHMRLEF---HNIETGIMTERRFISVVPSN 837

Query: 247 AAIKIGGRDQGRPFQGQVSGLYYNGLKVLALAAESD 282
                        F G +SGL +NG   +    + D
Sbjct: 838 -------------FIGHLSGLVFNGQPYMDQCKDGD 860



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 18/75 (24%), Positives = 38/75 (50%)

Query: 123 FSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVV 182
           FS  +R+       S++   DY  + +  G + ++ ++G+  I +   +  V+DG++  V
Sbjct: 501 FSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSRKVNDGEWCHV 560

Query: 183 RFTRSGGNATLQVDS 197
            F R G   ++ V+S
Sbjct: 561 DFQRDGRKGSISVNS 575



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 1/78 (1%)

Query: 119 LAVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVGTDDITIDEPNAIVSDGK 178
           L+    T+   A+L+ +D   G  D+L+L +  G + + F +   +    + +  V+D +
Sbjct: 53  LSFSLRTNATRALLLYLDDG-GDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDR 111

Query: 179 YHVVRFTRSGGNATLQVD 196
           +H+V  TR      L VD
Sbjct: 112 WHMVLLTRDARRTALAVD 129


>gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]
          Length = 1547

 Score =  439 bits (1130), Expect = e-123
 Identities = 215/284 (75%), Positives = 250/284 (88%), Gaps = 2/284 (0%)

Query: 90   GTTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI 149
            GTTYIF KGG  ITY WPPNDRPSTR DRLA+GFST Q+ AVLVRVDS+SGLGDYL+LHI
Sbjct: 1163 GTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHI 1222

Query: 150  DQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNF 209
             QG +GV FNVGTDDI I+E NAI++DGKYHVVRFTRSGGNATLQVDSWPV ERYPAGN 
Sbjct: 1223 HQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPAGNN 1282

Query: 210  DNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYY 269
            DNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQA I IGG++QG+PFQGQ+SGLYY
Sbjct: 1283 DNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYY 1342

Query: 270  NGLKVLALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATT 329
            NGLKVL +AAE+D N+   G++RLVGE PS  ++ E+TAT + ++M+T+IMETTTT+AT+
Sbjct: 1343 NGLKVLNMAAENDANIAIVGNVRLVGEVPS-SMTTESTATAMQSEMSTSIMETTTTLATS 1401

Query: 330  TTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGG 373
            T RRG+ PT ++  +Q TDD+LVASAECPSDDED++ CEPS+GG
Sbjct: 1402 TARRGKPPT-KEPISQTTDDILVASAECPSDDEDIDPCEPSSGG 1444



 Score =  164 bits (416), Expect = 2e-40
 Identities = 85/102 (83%), Positives = 91/102 (89%), Gaps = 1/102 (0%)

Query: 566  ANPTGPGERGP-PGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV 624
            ANPT  G R P PG+ EVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSY V
Sbjct: 1446 ANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHV 1505

Query: 625  DQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV 666
            D+SRNYISNSAQSNGAVVKEK P++ K+ +K KKNKDKEYYV
Sbjct: 1506 DESRNYISNSAQSNGAVVKEKQPSSAKSSNKNKKNKDKEYYV 1547



 Score = 37.7 bits (86), Expect = 0.034
 Identities = 23/93 (24%), Positives = 45/93 (48%), Gaps = 6/93 (6%)

Query: 97  KGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGV 156
           KG     Y    N   S+  D + + F T QR+ +++    ++   DY+ L +  G V +
Sbjct: 320 KGSEYFCYDLSQNPIQSSS-DEITLSFKTLQRNGLMLHTGKSA---DYVNLALKNGAVSL 375

Query: 157 IFNVGTD--DITIDEPNAIVSDGKYHVVRFTRS 187
           + N+G+   +  ++  N   +D  +H V+ TR+
Sbjct: 376 VINLGSGAFEALVEPVNGKFNDNAWHDVKVTRN 408


>gi|21070967 neurexin 1 isoform beta precursor [Homo sapiens]
          Length = 442

 Score =  419 bits (1078), Expect = e-117
 Identities = 229/374 (61%), Positives = 268/374 (71%), Gaps = 51/374 (13%)

Query: 2   PPGGSGPGGCPRRPPALAGPLPPPPPPPPPPLLPLLPLLLLLLLGAAEGARVSSSLSTTH 61
           P GG G GG       LA             LL ++PL L  LLG A GA   SSL   H
Sbjct: 15  PGGGGGGGGGGGAGGRLA-------------LLWIVPLTLSGLLGVAWGA---SSLGA-H 57

Query: 62  HVHHFH--SKHGTVPIAINRMPFLTRGGHAGTTYIFGKGGALITYTWPPNDRPSTRMDRL 119
           H+HHFH  SKH +VPIAI R P   RGGHAGTTYIF KGG  ITY WPPNDRPSTR DRL
Sbjct: 58  HIHHFHGSSKHHSVPIAIYRSPASLRGGHAGTTYIFSKGGGQITYKWPPNDRPSTRADRL 117

Query: 120 AVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVGTDDITIDEPNAIVSDGKY 179
           A+GFST Q+ AVLVRVDS+SGLGDYL+LHI QG +GV FNVGTDDI I+E NAI++DGKY
Sbjct: 118 AIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEESNAIINDGKY 177

Query: 180 HVVRFTRSGGNATLQVDSWPVNERYPAGNFDNERLAIARQRIPYRLGRVVDEWLLDKGRQ 239
           HVVRFTRSGGNATLQVDSWPV ERYPA                              GRQ
Sbjct: 178 HVVRFTRSGGNATLQVDSWPVIERYPA------------------------------GRQ 207

Query: 240 LTIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGLKVLALAAESDPNVRTEGHLRLVGEGPS 299
           LTIFNSQA I IGG++QG+PFQGQ+SGLYYNGLKVL +AAE+D N+   G++RLVGE PS
Sbjct: 208 LTIFNSQATIIIGGKEQGQPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPS 267

Query: 300 VLLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPS 359
             ++ E+TAT + ++M+T+IMETTTT+AT+T RRG+ PT ++  +Q TDD+LVASAECPS
Sbjct: 268 -SMTTESTATAMQSEMSTSIMETTTTLATSTARRGKPPT-KEPISQTTDDILVASAECPS 325

Query: 360 DDEDLEECEPSTGG 373
           DDED++ CEPS+GG
Sbjct: 326 DDEDIDPCEPSSGG 339



 Score =  164 bits (416), Expect = 2e-40
 Identities = 85/102 (83%), Positives = 91/102 (89%), Gaps = 1/102 (0%)

Query: 566 ANPTGPGERGP-PGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV 624
           ANPT  G R P PG+ EVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSY V
Sbjct: 341 ANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHV 400

Query: 625 DQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV 666
           D+SRNYISNSAQSNGAVVKEK P++ K+ +K KKNKDKEYYV
Sbjct: 401 DESRNYISNSAQSNGAVVKEKQPSSAKSSNKNKKNKDKEYYV 442


>gi|157427673 neurexin 3 isoform 3 precursor [Homo sapiens]
          Length = 459

 Score =  419 bits (1076), Expect = e-117
 Identities = 208/326 (63%), Positives = 255/326 (78%), Gaps = 7/326 (2%)

Query: 47  AAEGARVSSSLSTTHHVHHFH-SKHGTVPIAINRMPFLTRGGHAGTTYIFGKGGALITYT 105
           A+  +  SS  S + H HHFH SKH +VPI+I R P   RGGHAG TYIFGK G LI YT
Sbjct: 40  ASSSSTSSSPGSHSQHEHHFHGSKHHSVPISIYRSPVSLRGGHAGATYIFGKSGGLILYT 99

Query: 106 WPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVGTDDI 165
           WP NDRPSTR DRLAVGFST  +  +LVR+DSA GLGD+LQLHI+QG +GV+FN+GT DI
Sbjct: 100 WPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDI 159

Query: 166 TIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNFDNERLAIARQRIPYRL 225
           +I E    V+DGKYHVVRFTR+GGNATLQVD+WPVNE YP GN DNER  + +Q+IP++ 
Sbjct: 160 SIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGNTDNERFQMVKQKIPFKY 219

Query: 226 GRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGLKVLALAAESDPNV 285
            R V+EWL +KGRQLTIFN+QA I IGG+D+GR FQGQ+SGLYY+GLKVL +AAE++PN+
Sbjct: 220 NRPVEEWLQEKGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNI 279

Query: 286 RTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQ 345
           +  G +RLVGE PS+L + +T  T++  +M+TT+METTTTMATTTTR+ RS     ++ Q
Sbjct: 280 KINGSVRLVGEVPSILGTTQT--TSMPPEMSTTVMETTTTMATTTTRKNRS----TASIQ 333

Query: 346 NTDDLLVASAECPSDDEDLEECEPST 371
            T D LV+SAEC SDDED  ECEPST
Sbjct: 334 PTSDDLVSSAECSSDDEDFVECEPST 359



 Score =  157 bits (396), Expect = 4e-38
 Identities = 81/102 (79%), Positives = 90/102 (88%), Gaps = 1/102 (0%)

Query: 565 TANPTGPGERGPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV 624
           TANPT PG R  PGA EVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV
Sbjct: 359 TANPTEPGIRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV 418

Query: 625 DQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV 666
           D++RNYISNSAQSNG ++KEK  ++ K+  K +KNKD+EYYV
Sbjct: 419 DETRNYISNSAQSNGTLMKEKQQSS-KSGHKKQKNKDREYYV 459


>gi|41350305 neurexin 3 isoform 2 precursor [Homo sapiens]
          Length = 432

 Score =  370 bits (951), Expect = e-102
 Identities = 194/327 (59%), Positives = 234/327 (71%), Gaps = 37/327 (11%)

Query: 47  AAEGARVSSSLSTTHHVHHFH-SKHGTVPIAINRMPFLTRGGHAGTTYIFGKGGALITYT 105
           A+  +  SS  S + H HHFH SKH +VPI+I R P   RGGHAG TYIFGK G LI YT
Sbjct: 40  ASSSSTSSSPGSHSQHEHHFHGSKHHSVPISIYRSPVSLRGGHAGATYIFGKSGGLILYT 99

Query: 106 WPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGVIFNVGTDDI 165
           WP NDRPSTR DRLAVGFST  +  +LVR+DSA GLGD+LQLHI+QG +GV+FN+GT DI
Sbjct: 100 WPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDI 159

Query: 166 TIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNFDNERLAIARQRIPYRL 225
           +I E    V+DGKYHVVRFTR+GGNATLQVD+WPVNE YP                    
Sbjct: 160 SIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPT------------------- 200

Query: 226 GRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGLKVLALAAESDPNV 285
                      GRQLTIFN+QA I IGG+D+GR FQGQ+SGLYY+GLKVL +AAE++PN+
Sbjct: 201 -----------GRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNI 249

Query: 286 RTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQ 345
           +  G +RLVGE PS+L + +T  T++  +M+TT+METTTTMATTTTR+ RS     ++ Q
Sbjct: 250 KINGSVRLVGEVPSILGTTQT--TSMPPEMSTTVMETTTTMATTTTRKNRS----TASIQ 303

Query: 346 NTDDLLVASAECPSDDEDLEECEPSTG 372
            T D LV+SAEC SDDED  ECEPSTG
Sbjct: 304 PTSDDLVSSAECSSDDEDFVECEPSTG 330



 Score =  155 bits (392), Expect = 1e-37
 Identities = 80/102 (78%), Positives = 90/102 (88%), Gaps = 1/102 (0%)

Query: 565 TANPTGPGERGPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV 624
           +ANPT PG R  PGA EVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV
Sbjct: 332 SANPTEPGIRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV 391

Query: 625 DQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV 666
           D++RNYISNSAQSNG ++KEK  ++ K+  K +KNKD+EYYV
Sbjct: 392 DETRNYISNSAQSNGTLMKEKQQSS-KSGHKKQKNKDREYYV 432


>gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]
          Length = 1477

 Score =  366 bits (940), Expect = e-101
 Identities = 186/284 (65%), Positives = 221/284 (77%), Gaps = 32/284 (11%)

Query: 90   GTTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI 149
            GTTYIF KGG  ITY WPPNDRPSTR DRLA+GFST Q+ AVLVRVDS+SGLGDYL+LHI
Sbjct: 1123 GTTYIFSKGGGQITYKWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHI 1182

Query: 150  DQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNF 209
             QG +GV FNVGTDDI I+E NAI++DGKYHVVRFTRSGGNATLQVDSWPV ERYPA   
Sbjct: 1183 HQGKIGVKFNVGTDDIAIEESNAIINDGKYHVVRFTRSGGNATLQVDSWPVIERYPA--- 1239

Query: 210  DNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYY 269
                                       GRQLTIFNSQA I IGG++QG+PFQGQ+SGLYY
Sbjct: 1240 ---------------------------GRQLTIFNSQATIIIGGKEQGQPFQGQLSGLYY 1272

Query: 270  NGLKVLALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATT 329
            NGLKVL +AAE+D N+   G++RLVGE PS  ++ E+TAT + ++M+T+IMETTTT+AT+
Sbjct: 1273 NGLKVLNMAAENDANIAIVGNVRLVGEVPS-SMTTESTATAMQSEMSTSIMETTTTLATS 1331

Query: 330  TTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGG 373
            T RRG+ PT ++  +Q TDD+LVASAECPSDDED++ CEPS+GG
Sbjct: 1332 TARRGKPPT-KEPISQTTDDILVASAECPSDDEDIDPCEPSSGG 1374



 Score =  164 bits (416), Expect = 2e-40
 Identities = 85/102 (83%), Positives = 91/102 (89%), Gaps = 1/102 (0%)

Query: 566  ANPTGPGERGP-PGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV 624
            ANPT  G R P PG+ EVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSY V
Sbjct: 1376 ANPTRAGGREPYPGSAEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHV 1435

Query: 625  DQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV 666
            D+SRNYISNSAQSNGAVVKEK P++ K+ +K KKNKDKEYYV
Sbjct: 1436 DESRNYISNSAQSNGAVVKEKQPSSAKSSNKNKKNKDKEYYV 1477



 Score = 37.7 bits (86), Expect = 0.034
 Identities = 23/93 (24%), Positives = 45/93 (48%), Gaps = 6/93 (6%)

Query: 97  KGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHIDQGTVGV 156
           KG     Y    N   S+  D + + F T QR+ +++    ++   DY+ L +  G V +
Sbjct: 287 KGSEYFCYDLSQNPIQSSS-DEITLSFKTLQRNGLMLHTGKSA---DYVNLALKNGAVSL 342

Query: 157 IFNVGTD--DITIDEPNAIVSDGKYHVVRFTRS 187
           + N+G+   +  ++  N   +D  +H V+ TR+
Sbjct: 343 VINLGSGAFEALVEPVNGKFNDNAWHDVKVTRN 375


>gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens]
          Length = 1061

 Score =  328 bits (842), Expect = 7e-90
 Identities = 170/282 (60%), Positives = 205/282 (72%), Gaps = 36/282 (12%)

Query: 90  GTTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI 149
           G TYIFGK G LI YTWP NDRPSTR DRLAVGFST  +  +LVR+DSA GLGD+LQLHI
Sbjct: 716 GATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHI 775

Query: 150 DQGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNF 209
           +QG +GV+FN+GT DI+I E    V+DGKYHVVRFTR+GGNATLQVD+WPVNE YP    
Sbjct: 776 EQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPT--- 832

Query: 210 DNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYY 269
                                      GRQLTIFN+QA I IGG+D+GR FQGQ+SGLYY
Sbjct: 833 ---------------------------GRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYY 865

Query: 270 NGLKVLALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATT 329
           +GLKVL +AAE++PN++  G +RLVGE PS+L + +T  T++  +M+TT+METTTTMATT
Sbjct: 866 DGLKVLNMAAENNPNIKINGSVRLVGEVPSILGTTQT--TSMPPEMSTTVMETTTTMATT 923

Query: 330 TTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDLEECEPST 371
           TTR+ RS     ++ Q T D LV+SAEC SDDED  ECEPST
Sbjct: 924 TTRKNRS----TASIQPTSDDLVSSAECSSDDEDFVECEPST 961



 Score =  157 bits (396), Expect = 4e-38
 Identities = 81/102 (79%), Positives = 90/102 (88%), Gaps = 1/102 (0%)

Query: 565  TANPTGPGERGPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV 624
            TANPT PG R  PGA EVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV
Sbjct: 961  TANPTEPGIRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQV 1020

Query: 625  DQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV 666
            D++RNYISNSAQSNG ++KEK  ++ K+  K +KNKD+EYYV
Sbjct: 1021 DETRNYISNSAQSNGTLMKEKQQSS-KSGHKKQKNKDREYYV 1061


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 58/205 (28%), Positives = 79/205 (38%), Gaps = 16/205 (7%)

Query: 369  PSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARRPPSG 428
            P +  + + P +    L P P AT  P VP PP    F  G+G     L    +     G
Sbjct: 1306 PLSPPKSVPPSVPARGLQPQPPAT--PAVPHPPPSGAF--GLGGA---LEAAESEGLGLG 1358

Query: 429  GPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSPRKPAP 488
             P   +R D + +  +E     S +  DS     D ++  ++     D      P    P
Sbjct: 1359 CPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALD-----DPPLAGP 1413

Query: 489  RPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLEN--PPLGPGAPTSFEPRR 546
            +     DG   AP        P P LP+   N   P  PLLE   PP  P APT  +P+ 
Sbjct: 1414 KDTSTPDGPPLAPAAAVPGPPPLPGLPSANSN-GTPEPPLLEEKPPPTPPPAPTP-QPQP 1471

Query: 547  PPPLRPGVTSAPGFPHLPTANPTGP 571
            PPP  P   + P  P L    P+ P
Sbjct: 1472 PPPPPPPQPALPSPPPLVAPTPSSP 1496



 Score = 38.9 bits (89), Expect = 0.015
 Identities = 17/37 (45%), Positives = 20/37 (54%)

Query: 2    PPGGSGPGGCPRRPPALAGPLPPPPPPPPPPLLPLLP 38
            PP  + P   P   P  + P PPP PPPPPP +P  P
Sbjct: 1477 PPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPP 1513



 Score = 38.1 bits (87), Expect = 0.026
 Identities = 18/31 (58%), Positives = 19/31 (61%), Gaps = 1/31 (3%)

Query: 12   PRRPPA-LAGPLPPPPPPPPPPLLPLLPLLL 41
            P  PPA    P PPPPPPPP P LP  P L+
Sbjct: 1459 PTPPPAPTPQPQPPPPPPPPQPALPSPPPLV 1489



 Score = 37.7 bits (86), Expect = 0.034
 Identities = 46/166 (27%), Positives = 55/166 (33%), Gaps = 26/166 (15%)

Query: 425  PPSGGPCQAERDDSDCEEPIEA-------SGFASGEVFDSSLPPTDDEDFYTTFPLVTDR 477
            PP  GP      D     P  A        G  S     +  PP  +E    T P     
Sbjct: 1408 PPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTP 1467

Query: 478  TTLLSPRKPAPRPNLRTDGATGAPGVLFAP---SAPAPNLPAGKMNHRDPLQPLLENPPL 534
                 P  P P+P      A  +P  L AP   S P P LP        P  P + +PP 
Sbjct: 1468 QPQPPPPPPPPQP------ALPSPPPLVAPTPSSPPPPPLP-------PPPPPAMPSPP- 1513

Query: 535  GPGAPTSFEPRRPPPLRPGVTSAPGFPHLPTANPTGPGERGPPGAV 580
             P  P +  P   PP  P   S P  P LP   P    ++    AV
Sbjct: 1514 -PPPPPAAAPLAAPPEEPAAPS-PEDPELPDTRPLHLAKKQETAAV 1557



 Score = 37.4 bits (85), Expect = 0.045
 Identities = 13/16 (81%), Positives = 14/16 (87%)

Query: 21  PLPPPPPPPPPPLLPL 36
           P PPPPPPPPPP +PL
Sbjct: 833 PQPPPPPPPPPPPMPL 848



 Score = 36.6 bits (83), Expect = 0.077
 Identities = 16/27 (59%), Positives = 16/27 (59%), Gaps = 1/27 (3%)

Query: 12   PRRPPALAGPLPPPPPPPPPPLLPLLP 38
            P  PP    P P PPPPPPPP  P LP
Sbjct: 1458 PPTPPPAPTPQPQPPPPPPPP-QPALP 1483



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 20/49 (40%), Positives = 22/49 (44%), Gaps = 16/49 (32%)

Query: 3    PGGSGPGGCPRRPPAL-------------AGP---LPPPPPPPPPPLLP 35
            P   G G  P +PP L             +GP    PPPPPPPPPP  P
Sbjct: 1003 PETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAP 1051



 Score = 34.3 bits (77), Expect = 0.38
 Identities = 17/39 (43%), Positives = 18/39 (46%), Gaps = 2/39 (5%)

Query: 2    PPGGSGPGGCPRRPPALAGPLPPPPPPP--PPPLLPLLP 38
            PP    P      PP L  P P  PPPP  PPP  P +P
Sbjct: 1472 PPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMP 1510



 Score = 34.3 bits (77), Expect = 0.38
 Identities = 18/39 (46%), Positives = 18/39 (46%), Gaps = 4/39 (10%)

Query: 2    PPGGSGPGGCPRRPPALAGPLPP----PPPPPPPPLLPL 36
            PP    P      PP L  P PP    PPPPPPP   PL
Sbjct: 1485 PPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPL 1523



 Score = 33.1 bits (74), Expect = 0.85
 Identities = 22/53 (41%), Positives = 22/53 (41%), Gaps = 6/53 (11%)

Query: 3   PGGSGPGGCPRRPPALAGPLPPPPPPPPPPLLPLLPLLLLLLLGAAEGARVSS 55
           P G GP   P   P       PP PPPPP  LP    LL     AA  A  SS
Sbjct: 216 PAGLGPAQTPPYRPG------PPDPPPPPRHLPTQFNLLASSSAAAAAAEQSS 262



 Score = 33.1 bits (74), Expect = 0.85
 Identities = 18/39 (46%), Positives = 19/39 (48%), Gaps = 2/39 (5%)

Query: 3   PGGSGPGGCPRRPPALAGPLPPPPPPPPPPLLPLLPLLL 41
           P  S  G     P    G   PPPPPPPPP  P +PL L
Sbjct: 814 PSASKVGVHLLEPATRDGAPQPPPPPPPPP--PPMPLQL 850



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 23/73 (31%), Positives = 28/73 (38%), Gaps = 4/73 (5%)

Query: 484  RKPAPRPNL--RTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPTS 541
            RKP  RP +  R  G    P      SAP P  PA       P +   E PP     P +
Sbjct: 1664 RKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPP--EQTPET 1721

Query: 542  FEPRRPPPLRPGV 554
              P  P P +P +
Sbjct: 1722 AMPEPPAPEKPSL 1734



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 17/43 (39%), Positives = 19/43 (44%), Gaps = 12/43 (27%)

Query: 2    PPGGSGPGGCPRRPPALAGPLPPPPPPP------PPPLLPLLP 38
            PP    P   P+  P      PPPPPPP      PPPL+   P
Sbjct: 1457 PPPTPPPAPTPQPQP------PPPPPPPQPALPSPPPLVAPTP 1493



 Score = 29.6 bits (65), Expect = 9.4
 Identities = 21/70 (30%), Positives = 27/70 (38%), Gaps = 5/70 (7%)

Query: 387  PPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARRPPSGGP---CQAERDDSDCEEP 443
            PPP A  SP  PPPP   P        +   P P     P   P    + +   + C E 
Sbjct: 1504 PPPPAMPSPPPPPPPAAAPL--AAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGET 1561

Query: 444  IEASGFASGE 453
             E +G + GE
Sbjct: 1562 DEEAGESGGE 1571


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 65/239 (27%), Positives = 86/239 (35%), Gaps = 42/239 (17%)

Query: 376 ILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARRPPSGGPCQAER 435
           + P  T  S  PP +A     VPP P   P ++         PPP A  P +  P Q   
Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS-----PSATPPPQAPPPLAAPPLQ--- 736

Query: 436 DDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLS-PRKPAPRPNLRT 494
                   +  S  AS  +  S+ PP          PL    +   S P  P  +P  + 
Sbjct: 737 --------VPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA 788

Query: 495 DGATGAPGVLFAPSAPAP-----------NLPAGKMNHRDP------LQPLLENPPLGPG 537
             A   P +   PS PA            +LP   +    P        PLL+ PP  P 
Sbjct: 789 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 848

Query: 538 APTSFEPRRPPPLRPGVTSAPGFPHLPTA---NPTGPGERGPPGAV---EVIRESSSTT 590
           +PT   PRRPP   PG  ++   P L  A    P  P  R P   +   ++   SSS T
Sbjct: 849 SPTLQAPRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 905



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 55/200 (27%), Positives = 67/200 (33%), Gaps = 36/200 (18%)

Query: 378  PIITEDSLDPPPVATRSPFVPPPPTFYPFL------------TGVGATQDTL------PP 419
            P+ T     PP +A     VPP P   P L            T V   + TL      PP
Sbjct: 823  PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 882

Query: 420  PAARRPPS--GGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDR 477
            P +R P S   GP  A    S    P E  G+ SG    ++  P  D +     P    R
Sbjct: 883  PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 942

Query: 478  TTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPG 537
                      P P L   GA GAP  L  P A  P    G     +      E P     
Sbjct: 943  ---------GPAPPLAFRGAPGAP--LPWPPATGPGSADGLCTIYE-----TEGPESATP 986

Query: 538  APTSFEPRRPPPLRPGVTSA 557
            AP + +P   P    G  +A
Sbjct: 987  APGALDPGPSPGTSGGKAAA 1006



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 63/237 (26%), Positives = 84/237 (35%), Gaps = 31/237 (13%)

Query: 381 TEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQD--TLPPPAARRPPS-GGPCQ--AER 435
           TE  L  P  + R    P PPT  P  +   A++   T P PAARR PS GG  Q  A R
Sbjct: 185 TEVGLPRPAPSAR----PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240

Query: 436 DDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSPRK---PAPRPNL 492
             S    P+ +   +      +   P                  +  PRK   PA  P  
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300

Query: 493 RTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENP----PLGPGAPTSFEPRRPP 548
            +  AT +P    A   P P+  A  +    P  P L  P    P  P AP S +    P
Sbjct: 301 SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360

Query: 549 PLRPGVTSAPGF--------PHLPTANP-------TGPGERGPPGAVEVIRESSSTT 590
           P  P   + P          P L T  P       T P  + PP  + +    ++T+
Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS 417



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 62/235 (26%), Positives = 83/235 (35%), Gaps = 40/235 (17%)

Query: 369 PSTGGELILPIITEDS--------LDP-PPVATRSPFVPPPPTFYPFLTGVGATQDTLP- 418
           PS  G    P+   D+        L P PP+AT  P  PP P+  P L  + +   T P 
Sbjct: 307 PSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPS 366

Query: 419 --PPAARRPPSGGPCQAER----------DDSDCEEPIEASGFASGEVFDSSLPPT--DD 464
             PP+   PP   P   +                + P      +S +   S   PT    
Sbjct: 367 QAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQAT 426

Query: 465 EDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPA-PNLPAGKMNHRD 523
             F T  P  T + +L SP +PA  P         +P +    S PA P L         
Sbjct: 427 HSFLTMSPRQT-QASLTSPSRPASTP-------PDSPPLQAPLSLPASPPLQTSLSPAVS 478

Query: 524 PL-QPLLENPPLGPGAPTSFEPRRP------PPLRPGVTSAPGFPHLPTANPTGP 571
           PL  PL  +P     +  S  P+ P      PPL    + AP     P A+ T P
Sbjct: 479 PLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTP 533



 Score = 39.3 bits (90), Expect = 0.012
 Identities = 55/225 (24%), Positives = 75/225 (33%), Gaps = 32/225 (14%)

Query: 378 PIITEDSLDPPPVATR-SPFVPPPPTFYPFLTG--VGATQDTLPPPAARRPPSGGPCQAE 434
           P+ T+ SL PP + T  +    PP    P L    +      L  P    PP   PC  +
Sbjct: 511 PLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQ 570

Query: 435 RDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSP-RKPAPR---- 489
              S    P   +  +       + PP        + PL    +  LSP   P P+    
Sbjct: 571 APPSPLTTPPPETPSSI------ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPX 624

Query: 490 ---PNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEPRR 546
              P L+   +  A   L   + P+P  P     H   L     +PP  P     F P  
Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH---LLQAPFSPPPSPPVQAPFSPPA 681

Query: 547 PPPLRPGVT---------SAPGF---PHLPTANPTGPGERGPPGA 579
            PP+ P  T         +AP     P  P + P  P    PP A
Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 726



 Score = 33.5 bits (75), Expect = 0.65
 Identities = 19/39 (48%), Positives = 21/39 (53%), Gaps = 4/39 (10%)

Query: 1   MPPGGSGPGGCPRRPPALAGPLPPPPPPPPPPLLPLLPL 39
           M P  + P   PR PP LA P P   PP PP  LP+ PL
Sbjct: 747 MSPSATPP---PRVPPLLAAP-PLQVPPSPPASLPMSPL 781



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 4/35 (11%)

Query: 14 RPPALAGPLPPPPPPPPPPLLPLLPLLLLLLLGAA 48
          R P L  P PP  P PPPP+ P      L +LGAA
Sbjct: 20 RAPGLLTPRPPGSPRPPPPVTP----AALRVLGAA 50



 Score = 32.0 bits (71), Expect = 1.9
 Identities = 19/39 (48%), Positives = 20/39 (51%), Gaps = 11/39 (28%)

Query: 12  PRRPPALAGP----LPPP-------PPPPPPPLLPLLPL 39
           P+ PPALA P    LP P       PPP  PP L L PL
Sbjct: 592 PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPL 630



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 48/197 (24%), Positives = 66/197 (33%), Gaps = 33/197 (16%)

Query: 378 PIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPP-----PAARRPPSGGPCQ 432
           P+ +     P P  T++  VPPP       T + AT    PP     P A   PS  P  
Sbjct: 298 PLSSSPLATPSPSGTKARPVPPPDN---AATPLPATLPPSPPLATPLPLAPPSPSAPPSL 354

Query: 433 AERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSPRKPAP---- 488
                     P +A           + PP        T P +    +L SP   AP    
Sbjct: 355 QTLPSPPATPPSQAPP-------SMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPL 407

Query: 489 -RPNLRTDGATGAPG-------VLFAP-----SAPAPNLPAGKMNHRDPLQPLLENPPLG 535
              +L+   + G+P        +  +P     S  +P+ PA       PLQ  L + P  
Sbjct: 408 ALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPL-SLPAS 466

Query: 536 PGAPTSFEPRRPPPLRP 552
           P   TS  P   P   P
Sbjct: 467 PPLQTSLSPAVSPLSSP 483



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 15/27 (55%), Positives = 16/27 (59%), Gaps = 2/27 (7%)

Query: 12  PRRPPALAGP--LPPPPPPPPPPLLPL 36
           P+ PP LA P    PP PP  PPL PL
Sbjct: 619 PQAPPXLALPPLQAPPSPPASPPLSPL 645



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 5/37 (13%)

Query: 1   MPPGGSGPGGCPRRPPALAGP--LPPPPPPPPPPLLP 35
           M P  + P   P+ PP LA P    PP PP  PP+ P
Sbjct: 716 MSPSATPP---PQAPPPLAAPPLQVPPSPPASPPMSP 749


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 80/311 (25%), Positives = 109/311 (35%), Gaps = 43/311 (13%)

Query: 303 SAETTATTLLADMATTIMETTTTMATTTTRRGRS----PTLRDSTT---QNTDDLLVASA 355
           SA  +  TL +  AT   + TT++ + T +   S    P L    T   Q    L +   
Sbjct: 346 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 405

Query: 356 ECPSDD------EDLEECEPSTGGELILPIITEDSLDPPPVATRSPFVPPP-PTFYPFLT 408
           + P           L    P     L + ++      PP    ++PF PP  P   P  T
Sbjct: 406 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 465

Query: 409 GVGATQDTLPPPAARRPPSGGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFY 468
                  +L  P  + PPS  P  +         P +A    +      + PP       
Sbjct: 466 PPSQAPPSLAAPPLQVPPS--PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 523

Query: 469 TTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDP---L 525
            T PL         P  PA  P         AP   F+PSA  P  P      + P    
Sbjct: 524 ATPPLQA------LPSPPASFPGQ-------AP---FSPSASLPMSPLATPPPQAPPVLA 567

Query: 526 QPLLENPPLGPGAPTSFEPRRPPPLRPGVTSAPGFPHLPTA---NPTGPGERGPPGAV-- 580
            PLL+ PP  P +PT   PRRPP   PG  ++   P L  A    P  P  R P   +  
Sbjct: 568 APLLQVPPSPPASPTLQAPRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG 625

Query: 581 -EVIRESSSTT 590
            ++   SSS T
Sbjct: 626 PDLAGHSSSAT 636



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 55/200 (27%), Positives = 67/200 (33%), Gaps = 36/200 (18%)

Query: 378 PIITEDSLDPPPVATRSPFVPPPPTFYPFL------------TGVGATQDTL------PP 419
           P+ T     PP +A     VPP P   P L            T V   + TL      PP
Sbjct: 554 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 613

Query: 420 PAARRPPS--GGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDR 477
           P +R P S   GP  A    S    P E  G+ SG    ++  P  D +     P    R
Sbjct: 614 PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 673

Query: 478 TTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPG 537
                     P P L   GA GAP  L  P A  P    G     +      E P     
Sbjct: 674 ---------GPAPPLAFRGAPGAP--LPWPPATGPGSADGLCTIYE-----TEGPESATP 717

Query: 538 APTSFEPRRPPPLRPGVTSA 557
           AP + +P   P    G  +A
Sbjct: 718 APGALDPGPSPGTSGGKAAA 737



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 64/219 (29%), Positives = 79/219 (36%), Gaps = 27/219 (12%)

Query: 381 TEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQD--TLPPPAARRPPS-GGPCQ--AER 435
           TE  L  P  + R    P PPT  P  +   A++   T P PAARR PS GG  Q  A R
Sbjct: 185 TEVGLPRPAPSAR----PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240

Query: 436 DDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSPRK---PAPRPNL 492
             S    P+ +   +      +   P                  +  PRK   PA  P  
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300

Query: 493 RTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENP----PLGPGAPTSFEPRRPP 548
            +  AT +P       AP P LPA    H   L   L  P    P  P AP S +    P
Sbjct: 301 SSPLATPSPSAALQSQAP-PTLPA--TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSP 357

Query: 549 PLRP--GVTSAPGFPHLPTAN------PTGPGERGPPGA 579
           P  P    T++ G P L   +      P  P    PP A
Sbjct: 358 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 396



 Score = 37.7 bits (86), Expect = 0.034
 Identities = 64/252 (25%), Positives = 77/252 (30%), Gaps = 47/252 (18%)

Query: 369 PSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPP-------- 420
           PS      L  +      PP  AT S   P     + FL     +    PPP        
Sbjct: 343 PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL 402

Query: 421 ----AARRPPSGGPCQAERDDS------------------DCEEPIEA--SGFASGEVFD 456
               A   PP+  P       S                      P++A  S  AS  V  
Sbjct: 403 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 462

Query: 457 SSLPPTDDEDFYTTFPL-VTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLP 515
           S+ PP+         PL V        P  P+  P  +      AP +  A   P P  P
Sbjct: 463 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA--KPPPQAP 520

Query: 516 AGKMNHRDPLQPLLENP-------PLGPGAPTSFEP-RRPPPLRPGVTSAP--GFPHLPT 565
                   PLQ L   P       P  P A     P   PPP  P V +AP    P  P 
Sbjct: 521 PALAT--PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 578

Query: 566 ANPTGPGERGPP 577
           A+PT    R PP
Sbjct: 579 ASPTLQAPRRPP 590



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 4/35 (11%)

Query: 14 RPPALAGPLPPPPPPPPPPLLPLLPLLLLLLLGAA 48
          R P L  P PP  P PPPP+ P      L +LGAA
Sbjct: 20 RAPGLLTPRPPGSPRPPPPVTP----AALRVLGAA 50



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 16/27 (59%), Positives = 17/27 (62%), Gaps = 2/27 (7%)

Query: 12  PRRPPALAGP--LPPPPPPPPPPLLPL 36
           P+ PPALA P    PP PP  PPL PL
Sbjct: 394 PQAPPALALPPLQAPPSPPASPPLSPL 420


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 80/311 (25%), Positives = 109/311 (35%), Gaps = 43/311 (13%)

Query: 303 SAETTATTLLADMATTIMETTTTMATTTTRRGRS----PTLRDSTT---QNTDDLLVASA 355
           SA  +  TL +  AT   + TT++ + T +   S    P L    T   Q    L +   
Sbjct: 307 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 366

Query: 356 ECPSDD------EDLEECEPSTGGELILPIITEDSLDPPPVATRSPFVPPP-PTFYPFLT 408
           + P           L    P     L + ++      PP    ++PF PP  P   P  T
Sbjct: 367 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 426

Query: 409 GVGATQDTLPPPAARRPPSGGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFY 468
                  +L  P  + PPS  P  +         P +A    +      + PP       
Sbjct: 427 PPSQAPPSLAAPPLQVPPS--PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 484

Query: 469 TTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDP---L 525
            T PL         P  PA  P         AP   F+PSA  P  P      + P    
Sbjct: 485 ATPPLQA------LPSPPASFPGQ-------AP---FSPSASLPMSPLATPPPQAPPVLA 528

Query: 526 QPLLENPPLGPGAPTSFEPRRPPPLRPGVTSAPGFPHLPTA---NPTGPGERGPPGAV-- 580
            PLL+ PP  P +PT   PRRPP   PG  ++   P L  A    P  P  R P   +  
Sbjct: 529 APLLQVPPSPPASPTLQAPRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG 586

Query: 581 -EVIRESSSTT 590
            ++   SSS T
Sbjct: 587 PDLAGHSSSAT 597



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 55/200 (27%), Positives = 67/200 (33%), Gaps = 36/200 (18%)

Query: 378 PIITEDSLDPPPVATRSPFVPPPPTFYPFL------------TGVGATQDTL------PP 419
           P+ T     PP +A     VPP P   P L            T V   + TL      PP
Sbjct: 515 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 574

Query: 420 PAARRPPS--GGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDR 477
           P +R P S   GP  A    S    P E  G+ SG    ++  P  D +     P    R
Sbjct: 575 PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 634

Query: 478 TTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPG 537
                     P P L   GA GAP  L  P A  P    G     +      E P     
Sbjct: 635 ---------GPAPPLAFRGAPGAP--LPWPPATGPGSADGLCTIYE-----TEGPESATP 678

Query: 538 APTSFEPRRPPPLRPGVTSA 557
           AP + +P   P    G  +A
Sbjct: 679 APGALDPGPSPGTSGGKAAA 698



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 55/199 (27%), Positives = 71/199 (35%), Gaps = 30/199 (15%)

Query: 385 LDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARRPPSGGPCQAERDDSDCEEPI 444
           L   P+AT SP  PP P+  P L        TLP      PP+  P QA           
Sbjct: 290 LSSSPLATPSPSAPPSPSAPPSL-------QTLP-----SPPATPPSQATTSLGSPTLQA 337

Query: 445 EASGFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLS-PRKPAPRPNLRTDGATGAPGV 503
             S   S  +   + PP          PL    +   S P  P   P+ +   A  A  +
Sbjct: 338 THSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL-AVHL 396

Query: 504 LFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEPRRPPPLRPGVTSAPGF--- 560
           L AP +P P+ P      + P  P   +PP+ P A        PP   P   +AP     
Sbjct: 397 LQAPFSPPPSPPV-----QAPFSP-PASPPVSPSA-------TPPSQAPPSLAAPPLQVP 443

Query: 561 PHLPTANPTGPGERGPPGA 579
           P  P + P  P    PP A
Sbjct: 444 PSPPASPPMSPSATPPPQA 462



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 74/269 (27%), Positives = 95/269 (35%), Gaps = 51/269 (18%)

Query: 381 TEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQD--TLPPPAARRPPS-GGPCQ--AER 435
           TE  L  P  + R    P PPT  P  +   A++   T P PAARR PS GG  Q  A R
Sbjct: 176 TEVGLPRPAPSAR----PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 231

Query: 436 DDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSPRK---PAPRPNL 492
             S    P+ +   +      +   P                  +  PRK   PA  P  
Sbjct: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 291

Query: 493 RTDGATGAPGVLFAPSAP-----APNLPAGKMNH------------------RDPLQPLL 529
            +  AT +P    +PSAP      P+ PA   +                     PL PL 
Sbjct: 292 SSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA 351

Query: 530 ENPPLGPGA----PTSFEPRRP--PPLRPGVTSAPGFP-----HL---PTANPTGPGERG 575
             PP  P A    P    P  P  PPL P  T +P  P     HL   P + P  P  + 
Sbjct: 352 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 411

Query: 576 P--PGAVEVIRESSSTTGMVVGIVAAAAL 602
           P  P A   +  S++        +AA  L
Sbjct: 412 PFSPPASPPVSPSATPPSQAPPSLAAPPL 440



 Score = 37.7 bits (86), Expect = 0.034
 Identities = 64/252 (25%), Positives = 77/252 (30%), Gaps = 47/252 (18%)

Query: 369 PSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPP-------- 420
           PS      L  +      PP  AT S   P     + FL     +    PPP        
Sbjct: 304 PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL 363

Query: 421 ----AARRPPSGGPCQAERDDS------------------DCEEPIEA--SGFASGEVFD 456
               A   PP+  P       S                      P++A  S  AS  V  
Sbjct: 364 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 423

Query: 457 SSLPPTDDEDFYTTFPL-VTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLP 515
           S+ PP+         PL V        P  P+  P  +      AP +  A   P P  P
Sbjct: 424 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA--KPPPQAP 481

Query: 516 AGKMNHRDPLQPLLENP-------PLGPGAPTSFEP-RRPPPLRPGVTSAP--GFPHLPT 565
                   PLQ L   P       P  P A     P   PPP  P V +AP    P  P 
Sbjct: 482 PALAT--PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 539

Query: 566 ANPTGPGERGPP 577
           A+PT    R PP
Sbjct: 540 ASPTLQAPRRPP 551



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 4/35 (11%)

Query: 14 RPPALAGPLPPPPPPPPPPLLPLLPLLLLLLLGAA 48
          R P L  P PP  P PPPP+ P      L +LGAA
Sbjct: 20 RAPGLLTPRPPGSPRPPPPVTP----AALRVLGAA 50



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 16/27 (59%), Positives = 17/27 (62%), Gaps = 2/27 (7%)

Query: 12  PRRPPALAGP--LPPPPPPPPPPLLPL 36
           P+ PPALA P    PP PP  PPL PL
Sbjct: 355 PQAPPALALPPLQAPPSPPASPPLSPL 381


>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
           [Homo sapiens]
          Length = 1285

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 49/177 (27%), Positives = 70/177 (39%), Gaps = 25/177 (14%)

Query: 412 ATQDTLPPPAARRPPSGGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTF 471
           A+ ++L P + R  PSG              P +A   AS E+   S P       +T+ 
Sbjct: 746 ASAESLEPVSWREGPSGHSTLPR-------SPRDAPCSASSELSGPSTP------LHTSS 792

Query: 472 PLV-TDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLE 530
           P+   + T     R P   P  R       P V  A +  AP LP+G  +  +PL P   
Sbjct: 793 PVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSG--SGPEPLAPSPV 850

Query: 531 NPPLGPGAPTSFEPRRPP--------PLRPGVTSAPGFPHLPTANPTGPGERGPPGA 579
           +P   P +P+ +   R P        P  P  T+ PG  H P   P GP +  P G+
Sbjct: 851 SPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPD-SPDGS 906



 Score = 32.0 bits (71), Expect = 1.9
 Identities = 14/31 (45%), Positives = 15/31 (48%)

Query: 3   PGGSGPGGCPRRPPALAGPLPPPPPPPPPPL 33
           P    P    +RPP    P P P PPPPP L
Sbjct: 353 PLDGSPYAQVQRPPRQTPPAPSPEPPPPPML 383


>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
            [Homo sapiens]
          Length = 1409

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 49/177 (27%), Positives = 70/177 (39%), Gaps = 25/177 (14%)

Query: 412  ATQDTLPPPAARRPPSGGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTF 471
            A+ ++L P + R  PSG              P +A   AS E+   S P       +T+ 
Sbjct: 870  ASAESLEPVSWREGPSGHSTLPR-------SPRDAPCSASSELSGPSTP------LHTSS 916

Query: 472  PLV-TDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLE 530
            P+   + T     R P   P  R       P V  A +  AP LP+G  +  +PL P   
Sbjct: 917  PVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSG--SGPEPLAPSPV 974

Query: 531  NPPLGPGAPTSFEPRRPP--------PLRPGVTSAPGFPHLPTANPTGPGERGPPGA 579
            +P   P +P+ +   R P        P  P  T+ PG  H P   P GP +  P G+
Sbjct: 975  SPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPD-SPDGS 1030



 Score = 32.0 bits (71), Expect = 1.9
 Identities = 14/31 (45%), Positives = 15/31 (48%)

Query: 3   PGGSGPGGCPRRPPALAGPLPPPPPPPPPPL 33
           P    P    +RPP    P P P PPPPP L
Sbjct: 477 PLDGSPYAQVQRPPRQTPPAPSPEPPPPPML 507


>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
            [Homo sapiens]
          Length = 1419

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 49/177 (27%), Positives = 70/177 (39%), Gaps = 25/177 (14%)

Query: 412  ATQDTLPPPAARRPPSGGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTF 471
            A+ ++L P + R  PSG              P +A   AS E+   S P       +T+ 
Sbjct: 880  ASAESLEPVSWREGPSGHSTLPR-------SPRDAPCSASSELSGPSTP------LHTSS 926

Query: 472  PLV-TDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLE 530
            P+   + T     R P   P  R       P V  A +  AP LP+G  +  +PL P   
Sbjct: 927  PVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSG--SGPEPLAPSPV 984

Query: 531  NPPLGPGAPTSFEPRRPP--------PLRPGVTSAPGFPHLPTANPTGPGERGPPGA 579
            +P   P +P+ +   R P        P  P  T+ PG  H P   P GP +  P G+
Sbjct: 985  SPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPD-SPDGS 1040



 Score = 32.0 bits (71), Expect = 1.9
 Identities = 14/31 (45%), Positives = 15/31 (48%)

Query: 3   PGGSGPGGCPRRPPALAGPLPPPPPPPPPPL 33
           P    P    +RPP    P P P PPPPP L
Sbjct: 487 PLDGSPYAQVQRPPRQTPPAPSPEPPPPPML 517


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 53/203 (26%), Positives = 70/203 (34%), Gaps = 31/203 (15%)

Query: 399 PPPTFYPFLTGVGATQDTLPPPAARRPP-SGGPCQAERDDSDCEEPIEASGFASGEVFDS 457
           P P   P   G   +Q    PPA +RPP  GGP Q          P++      G+   S
Sbjct: 437 PSPGALPL--GRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLS 494

Query: 458 SLPPTDDEDFYTTFPLVTDRTTLLSPRKPAP----------RPNLRTDGATGAPGVLFAP 507
            L P          P  T      +P++PA           R +    G  GAP     P
Sbjct: 495 GLGPPAGSPLPQRLPSPTS-----APQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPP 549

Query: 508 SAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEPRRPPPLRPGVTSAP--------- 558
           ++P+P   AG              PP   GAP   + R+ PP +P   + P         
Sbjct: 550 ASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGP 609

Query: 559 ----GFPHLPTANPTGPGERGPP 577
               G P      P+GPG  G P
Sbjct: 610 VPRTGPPTTQQPRPSGPGPAGRP 632


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 53/203 (26%), Positives = 70/203 (34%), Gaps = 31/203 (15%)

Query: 399 PPPTFYPFLTGVGATQDTLPPPAARRPP-SGGPCQAERDDSDCEEPIEASGFASGEVFDS 457
           P P   P   G   +Q    PPA +RPP  GGP Q          P++      G+   S
Sbjct: 437 PSPGALPL--GRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLS 494

Query: 458 SLPPTDDEDFYTTFPLVTDRTTLLSPRKPAP----------RPNLRTDGATGAPGVLFAP 507
            L P          P  T      +P++PA           R +    G  GAP     P
Sbjct: 495 GLGPPAGSPLPQRLPSPTS-----APQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPP 549

Query: 508 SAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEPRRPPPLRPGVTSAP--------- 558
           ++P+P   AG              PP   GAP   + R+ PP +P   + P         
Sbjct: 550 ASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGP 609

Query: 559 ----GFPHLPTANPTGPGERGPP 577
               G P      P+GPG  G P
Sbjct: 610 VPRTGPPTTQQPRPSGPGPAGRP 632


>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
          Length = 756

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 54/204 (26%), Positives = 73/204 (35%), Gaps = 17/204 (8%)

Query: 375 LILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARRPPSGGPCQAE 434
           L LP +T+    P P    S   P PPT       V  T D+  PP      SG P    
Sbjct: 550 LALPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPP 609

Query: 435 RDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRT 494
             DS    P+  +G +        +PPT D       P        + P   +  P +  
Sbjct: 610 TGDSGA-PPVPPTGDSGA----PPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPP 664

Query: 495 DGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLEN--PPLGPGAPTSFEPRRPPPLRP 552
            G +GAP V     A  P +P    +   P+ P  ++  PP+ P   +   P  P     
Sbjct: 665 TGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPP----- 719

Query: 553 GVTSAPGFPHLPTANPTGPGERGP 576
             T   G P +P   PTG  E  P
Sbjct: 720 --TGDSGAPPVP---PTGDSEAAP 738



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 35/133 (26%), Positives = 50/133 (37%), Gaps = 9/133 (6%)

Query: 459 LPPTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGK 518
           +PPT D +     P     T  + P   +  P +   G +GAP V     + AP +P   
Sbjct: 563 VPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTG 622

Query: 519 MNHRDPLQPLLEN-----PPLG----PGAPTSFEPRRPPPLRPGVTSAPGFPHLPTANPT 569
            +   P+ P  ++     PP G    P  P + +   PP    G + AP  P    A P 
Sbjct: 623 DSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDAGPP 682

Query: 570 GPGERGPPGAVEV 582
                G  GA  V
Sbjct: 683 PVPPTGDSGAPPV 695


>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
          Length = 1303

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 65/252 (25%), Positives = 92/252 (36%), Gaps = 40/252 (15%)

Query: 339 LRDSTTQNTDDLLVASAECPSDDE-DLEECEPSTGGELILPIITEDSLDPPPVATRSPFV 397
           L + T +  D +L   AE  ++DE ++EE +      L  P      L  PP     P  
Sbjct: 470 LTEETRELLDKMLADDAEAGAEDEKEVEELKKQGINPLPKPPPGVGLLPTPP-RPPGPQA 528

Query: 398 PPPPTFYPFLTGVGATQDTLPPPAARRPPSGGPCQAERDDSDCEEPIEASGFASGEVFDS 457
           P  P   P   G        PPP    PP  GP Q         EP+        ++++ 
Sbjct: 529 PTSPNGRPMQGGP-------PPPPPPPPPPPGPPQM---PMPVHEPLSPQQLQQQDMYNK 578

Query: 458 SLPPTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNL-PA 516
            +P        + F +V   T  L     A +  +R  G  G PG    P  P PN+ P 
Sbjct: 579 KIP--------SLFEIVVRPTGQL-----AEKLGVRFPGPGGPPG----PMGPGPNMGPP 621

Query: 517 GKMNHRDPLQPLLE---NPPLGPGAPTSFEPRRP--PPLRPGVTSAPGFPHLPTANPTGP 571
           G M    P+ P +    +P + P          P  P + PG    PG P +    P GP
Sbjct: 622 GPMG--GPMHPDMHPDMHPDMHPDMHADMHADMPMGPGMNPGPPMGPGGPPM---MPYGP 676

Query: 572 GERGPPGAVEVI 583
           G+    G +  I
Sbjct: 677 GDSPHSGMMPPI 688



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 20/38 (52%), Positives = 22/38 (57%), Gaps = 1/38 (2%)

Query: 2   PPGGSGPGGCPRRPPALAGPLPPPPPPPPPPLLPLLPL 39
           PPG   P   P   P   GP PPPPPPPPPP  P +P+
Sbjct: 523 PPGPQAPTS-PNGRPMQGGPPPPPPPPPPPPGPPQMPM 559



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 14/29 (48%), Positives = 16/29 (55%), Gaps = 3/29 (10%)

Query: 10 GCPRRPPALAGPLPPPPP---PPPPPLLP 35
          G P  PP+ + P P PPP   P PPP  P
Sbjct: 6  GTPPPPPSESPPPPSPPPPSTPSPPPCSP 34



 Score = 29.6 bits (65), Expect = 9.4
 Identities = 11/20 (55%), Positives = 11/20 (55%)

Query: 12 PRRPPALAGPLPPPPPPPPP 31
          P  PP      PPPP PPPP
Sbjct: 5  PGTPPPPPSESPPPPSPPPP 24


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 77/312 (24%), Positives = 97/312 (31%), Gaps = 42/312 (13%)

Query: 298  PSVLLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDS------TTQNTDDLL 351
            P+   S  TT         TT+  TTT    TTT     PT   S       T  T    
Sbjct: 1496 PTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTT 1555

Query: 352  VASAECPSDDEDLEEC-------EPSTGGELILPIITEDSLDPPPVATRSP--------- 395
            +     PS                P T      P IT  +  PPP  T SP         
Sbjct: 1556 LPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTIT--TTTPPPTTTPSPPTTTTTTPP 1613

Query: 396  --FVPPPPTFYPFLTGVGATQDTLPPPAARRPPSGGPCQAERDDSDCEEPIEASGFASGE 453
                P PPT  P       T  TLPP     PP   P                +   S  
Sbjct: 1614 PTTTPSPPTTTPITPPTSTT--TLPPTTTPSPP---PTTTTTPPPTTTPSPPTTTTPSPP 1668

Query: 454  VFDSSLPP--TDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPA 511
            +  ++ PP  T      TT P  +  TT ++   P   P+      T  P     PS P 
Sbjct: 1669 ITTTTTPPPTTTPSSPITTTP--SPPTTTMTTPSPTTTPSSPIT-TTTTPSSTTTPSPPP 1725

Query: 512  PNL--PAGKMNHRDPLQPLLENPPLGPGAPTSFEPR----RPPPLRPGVTSAPGFPHLPT 565
              +  P+       P   +   PP    +P +  P      PP   P  T+ P  P +P 
Sbjct: 1726 TTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPL 1785

Query: 566  ANPTGPGERGPP 577
             N TG  + G P
Sbjct: 1786 CNWTGWLDSGKP 1797



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 71/293 (24%), Positives = 88/293 (30%), Gaps = 47/293 (16%)

Query: 298  PSVLLSAETTATTLLADMATTIMETTTTMATTTTRRGRSP----TLRDSTTQNTDDLLVA 353
            P+   S   T+TT L    T    TTTT     T     P    T    TT  +  +   
Sbjct: 1402 PTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTT 1461

Query: 354  SAECPSDDEDLEECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGAT 413
            +   P+         PS       P  T  +  PPP  T     P PPT  P       T
Sbjct: 1462 TTPPPTTTPSPPTTTPSPPTTTPSP-PTTTTTTPPPTTT-----PSPPTTTPITPPASTT 1515

Query: 414  QDTLPPPAARRPPSGGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPL 473
              TLPP     PP+                             ++ PPT      TT P+
Sbjct: 1516 --TLPPTTTPSPPT--------------------------TTTTTPPPTTTPSPPTTTPI 1547

Query: 474  V--TDRTTLLSPRKPAPRPNLRT---DGATGAPGVLFAPSAP--APNLPAGKMNHRDPLQ 526
               T  TTL     P+P P   T      T +P     PS P      P        P  
Sbjct: 1548 TPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTT 1607

Query: 527  PLLENPPLGPGAPTSFEPRRPPPLRPGV--TSAPGFPHLPTANPTGPGERGPP 577
                 PP    +P +  P  PP     +  T+ P  P   T  P       PP
Sbjct: 1608 TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPP 1660



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 57/226 (25%), Positives = 72/226 (31%), Gaps = 33/226 (14%)

Query: 381  TEDSLDPPPVATRSPFV----PPPPTFYPFLTGVGATQDTLPPPAARRPPSGGPCQAERD 436
            T  +  PPP  T SP +     PPPT  P  +   +T  T PP     PP+  P      
Sbjct: 1426 TTTTTTPPPTTTPSPPITTTTTPPPTTTP--SPPISTTTTPPPTTTPSPPTTTPSPPTTT 1483

Query: 437  DSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDG 496
             S    P   +         ++ PPT      TT P+    +T   P    P P   T  
Sbjct: 1484 PS---PPTTTT---------TTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTT-- 1529

Query: 497  ATGAPGVLFAPSAP----------APNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEPRR 546
             T  P     PS P             LP        P       P   P  PT+  P  
Sbjct: 1530 -TTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP 1588

Query: 547  P--PPLRPGVTSAPGFPHLPTANPTGPGERGPPGAVEVIRESSSTT 590
            P      P  T+ P  P   T  P       PP    +   +S+TT
Sbjct: 1589 PTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTT 1634



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 70/326 (21%), Positives = 100/326 (30%), Gaps = 36/326 (11%)

Query: 306  TTATTLLADMATTIMET-TTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPS---DD 361
            TT TT+      T  +T TTT  TTTT    +PT   + T  T  +   +   P+     
Sbjct: 3972 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4031

Query: 362  EDLEECEPSTGGELILPIITEDSLDPP---PVATRSPFVPPP-------PTFYPFLTGVG 411
                   P T    + P  T      P   P+ T +   P P       PT  P  T   
Sbjct: 4032 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4091

Query: 412  ATQDTLPPPAARRPPSGGPCQAERDDSDCEEPIEASGFASGEVFDSS----LPPTDDEDF 467
             T    P P   + P+  P       +    P       +  +  ++     P       
Sbjct: 4092 VT--PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4149

Query: 468  YTTFPLVTDRTTLLSP-----RKPAPRPNLRTDGATGAP---GVLFAPSAPAPNLPAGKM 519
             TT P+ T  T   +P     + P   P   T   T  P   G    P       P  ++
Sbjct: 4150 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAEL 4209

Query: 520  NHRDPLQPLLENPPLGPGA------PTSFEPRRPPPLRPGVTSAPGFPHLPTANPTGPGE 573
               +P  P    P             T+     PP +    T+ P  P  PT   +G   
Sbjct: 4210 TTSNP-PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTT-SGGHT 4267

Query: 574  RGPPGAVEVIRESSSTTGMVVGIVAA 599
              PP +       + T G   G  +A
Sbjct: 4268 LSPPPSTTTSPPGTPTRGTTTGSSSA 4293



 Score = 38.9 bits (89), Expect = 0.015
 Identities = 54/213 (25%), Positives = 63/213 (29%), Gaps = 22/213 (10%)

Query: 388  PPVATRSPFVPP------PPTFYPFLTGVGATQDTLPPPAARRPPSGGPCQAERDDSDCE 441
            PP  T SP  PP      PPT  P       T  T PPP     P           +   
Sbjct: 1401 PPTTTPSP--PPTSTTTLPPTTTP---SPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPS 1455

Query: 442  EPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAP 501
             PI  +         S  PPT      TT P     TT   P    P P   T   T   
Sbjct: 1456 PPISTTTTPPPTTTPS--PPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP-ITPPA 1512

Query: 502  GVLFAPSAPAPNLPAGKMNHRDPL---QPLLENPPLGPGAPTSFEPRRPPPLRPGVTSAP 558
                 P    P+ P        P     P    P   P + T+  P   P   P  T+ P
Sbjct: 1513 STTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP 1572

Query: 559  GFPHLPTANPTGPGERGP-PGAVEVIRESSSTT 590
                 PT  P+ P    P P  +       +TT
Sbjct: 1573 P----PTTTPSPPTTTTPSPPTITTTTPPPTTT 1601



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 62/271 (22%), Positives = 86/271 (31%), Gaps = 33/271 (12%)

Query: 306  TTATTLLADMATTIMET-TTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDL 364
            TT TT+      T  +T TTT  TTTT    +PT   + T  T  +   +   P+     
Sbjct: 1902 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 1961

Query: 365  EECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARR 424
             +   +T      PI T  ++ P P  T +      PT  P  T    T    P P   +
Sbjct: 1962 TQTPTTT------PITTTTTVTPTPTPTGT----QTPTTTPITTTTTVT--PTPTPTGTQ 2009

Query: 425  PPSGGPCQAERDDSDCEEPIEASGFASGEVFDSS----LPPTDDEDFYTTFPLVTDRTTL 480
             P+  P       +    P       +  +  ++     P        TT P+ T  T  
Sbjct: 2010 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV- 2068

Query: 481  LSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGP-GAP 539
                 P P P   T   T  P        P P  P G         P+     + P   P
Sbjct: 2069 ----TPTPTPT-GTQTPTTTPITTTTTVTPTPT-PTG--TQTPTTTPITTTTTVTPTPTP 2120

Query: 540  TSFEPRRPPPLRPGVTSAPGFPHLPTANPTG 570
            T  +     P+    T        PT  PTG
Sbjct: 2121 TGTQTPTTTPITTTTTVT------PTPTPTG 2145



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 62/271 (22%), Positives = 86/271 (31%), Gaps = 33/271 (12%)

Query: 306  TTATTLLADMATTIMET-TTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDL 364
            TT TT+      T  +T TTT  TTTT    +PT   + T  T  +   +   P+     
Sbjct: 2109 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2168

Query: 365  EECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARR 424
             +   +T      PI T  ++ P P  T +      PT  P  T    T    P P   +
Sbjct: 2169 TQTPTTT------PITTTTTVTPTPTPTGT----QTPTTTPITTTTTVT--PTPTPTGTQ 2216

Query: 425  PPSGGPCQAERDDSDCEEPIEASGFASGEVFDSS----LPPTDDEDFYTTFPLVTDRTTL 480
             P+  P       +    P       +  +  ++     P        TT P+ T  T  
Sbjct: 2217 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV- 2275

Query: 481  LSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGP-GAP 539
                 P P P   T   T  P        P P  P G         P+     + P   P
Sbjct: 2276 ----TPTPTPT-GTQTPTTTPITTTTTVTPTPT-PTG--TQTPTTTPITTTTTVTPTPTP 2327

Query: 540  TSFEPRRPPPLRPGVTSAPGFPHLPTANPTG 570
            T  +     P+    T        PT  PTG
Sbjct: 2328 TGTQTPTTTPITTTTTVT------PTPTPTG 2352



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 62/271 (22%), Positives = 86/271 (31%), Gaps = 33/271 (12%)

Query: 306  TTATTLLADMATTIMET-TTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDL 364
            TT TT+      T  +T TTT  TTTT    +PT   + T  T  +   +   P+     
Sbjct: 2316 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2375

Query: 365  EECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARR 424
             +   +T      PI T  ++ P P  T +      PT  P  T    T    P P   +
Sbjct: 2376 TQTPTTT------PITTTTTVTPTPTPTGT----QTPTTTPITTTTTVT--PTPTPTGTQ 2423

Query: 425  PPSGGPCQAERDDSDCEEPIEASGFASGEVFDSS----LPPTDDEDFYTTFPLVTDRTTL 480
             P+  P       +    P       +  +  ++     P        TT P+ T  T  
Sbjct: 2424 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV- 2482

Query: 481  LSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGP-GAP 539
                 P P P   T   T  P        P P  P G         P+     + P   P
Sbjct: 2483 ----TPTPTPT-GTQTPTTTPITTTTTVTPTPT-PTG--TQTPTTTPITTTTTVTPTPTP 2534

Query: 540  TSFEPRRPPPLRPGVTSAPGFPHLPTANPTG 570
            T  +     P+    T        PT  PTG
Sbjct: 2535 TGTQTPTTTPITTTTTVT------PTPTPTG 2559



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 62/271 (22%), Positives = 86/271 (31%), Gaps = 33/271 (12%)

Query: 306  TTATTLLADMATTIMET-TTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDL 364
            TT TT+      T  +T TTT  TTTT    +PT   + T  T  +   +   P+     
Sbjct: 2523 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2582

Query: 365  EECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARR 424
             +   +T      PI T  ++ P P  T +      PT  P  T    T    P P   +
Sbjct: 2583 TQTPTTT------PITTTTTVTPTPTPTGT----QTPTTTPITTTTTVT--PTPTPTGTQ 2630

Query: 425  PPSGGPCQAERDDSDCEEPIEASGFASGEVFDSS----LPPTDDEDFYTTFPLVTDRTTL 480
             P+  P       +    P       +  +  ++     P        TT P+ T  T  
Sbjct: 2631 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV- 2689

Query: 481  LSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGP-GAP 539
                 P P P   T   T  P        P P  P G         P+     + P   P
Sbjct: 2690 ----TPTPTPT-GTQTPTTTPITTTTTVTPTPT-PTG--TQTPTTTPITTTTTVTPTPTP 2741

Query: 540  TSFEPRRPPPLRPGVTSAPGFPHLPTANPTG 570
            T  +     P+    T        PT  PTG
Sbjct: 2742 TGTQTPTTTPITTTTTVT------PTPTPTG 2766



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 62/271 (22%), Positives = 86/271 (31%), Gaps = 33/271 (12%)

Query: 306  TTATTLLADMATTIMET-TTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDL 364
            TT TT+      T  +T TTT  TTTT    +PT   + T  T  +   +   P+     
Sbjct: 2730 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2789

Query: 365  EECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARR 424
             +   +T      PI T  ++ P P  T +      PT  P  T    T    P P   +
Sbjct: 2790 TQTPTTT------PITTTTTVTPTPTPTGT----QTPTTTPITTTTTVT--PTPTPTGTQ 2837

Query: 425  PPSGGPCQAERDDSDCEEPIEASGFASGEVFDSS----LPPTDDEDFYTTFPLVTDRTTL 480
             P+  P       +    P       +  +  ++     P        TT P+ T  T  
Sbjct: 2838 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV- 2896

Query: 481  LSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGP-GAP 539
                 P P P   T   T  P        P P  P G         P+     + P   P
Sbjct: 2897 ----TPTPTPT-GTQTPTTTPITTTTTVTPTPT-PTG--TQTPTTTPITTTTTVTPTPTP 2948

Query: 540  TSFEPRRPPPLRPGVTSAPGFPHLPTANPTG 570
            T  +     P+    T        PT  PTG
Sbjct: 2949 TGTQTPTTTPITTTTTVT------PTPTPTG 2973



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 62/271 (22%), Positives = 86/271 (31%), Gaps = 33/271 (12%)

Query: 306  TTATTLLADMATTIMET-TTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDL 364
            TT TT+      T  +T TTT  TTTT    +PT   + T  T  +   +   P+     
Sbjct: 2937 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2996

Query: 365  EECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARR 424
             +   +T      PI T  ++ P P  T +      PT  P  T    T    P P   +
Sbjct: 2997 TQTPTTT------PITTTTTVTPTPTPTGT----QTPTTTPITTTTTVT--PTPTPTGTQ 3044

Query: 425  PPSGGPCQAERDDSDCEEPIEASGFASGEVFDSS----LPPTDDEDFYTTFPLVTDRTTL 480
             P+  P       +    P       +  +  ++     P        TT P+ T  T  
Sbjct: 3045 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV- 3103

Query: 481  LSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGP-GAP 539
                 P P P   T   T  P        P P  P G         P+     + P   P
Sbjct: 3104 ----TPTPTPT-GTQTPTTTPITTTTTVTPTPT-PTG--TQTPTTTPITTTTTVTPTPTP 3155

Query: 540  TSFEPRRPPPLRPGVTSAPGFPHLPTANPTG 570
            T  +     P+    T        PT  PTG
Sbjct: 3156 TGTQTPTTTPITTTTTVT------PTPTPTG 3180



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 62/271 (22%), Positives = 86/271 (31%), Gaps = 33/271 (12%)

Query: 306  TTATTLLADMATTIMET-TTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDL 364
            TT TT+      T  +T TTT  TTTT    +PT   + T  T  +   +   P+     
Sbjct: 3144 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3203

Query: 365  EECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARR 424
             +   +T      PI T  ++ P P  T +      PT  P  T    T    P P   +
Sbjct: 3204 TQTPTTT------PITTTTTVTPTPTPTGT----QTPTTTPITTTTTVT--PTPTPTGTQ 3251

Query: 425  PPSGGPCQAERDDSDCEEPIEASGFASGEVFDSS----LPPTDDEDFYTTFPLVTDRTTL 480
             P+  P       +    P       +  +  ++     P        TT P+ T  T  
Sbjct: 3252 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV- 3310

Query: 481  LSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGP-GAP 539
                 P P P   T   T  P        P P  P G         P+     + P   P
Sbjct: 3311 ----TPTPTPT-GTQTPTTTPITTTTTVTPTPT-PTG--TQTPTTTPITTTTTVTPTPTP 3362

Query: 540  TSFEPRRPPPLRPGVTSAPGFPHLPTANPTG 570
            T  +     P+    T        PT  PTG
Sbjct: 3363 TGTQTPTTTPITTTTTVT------PTPTPTG 3387



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 62/271 (22%), Positives = 86/271 (31%), Gaps = 33/271 (12%)

Query: 306  TTATTLLADMATTIMET-TTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDL 364
            TT TT+      T  +T TTT  TTTT    +PT   + T  T  +   +   P+     
Sbjct: 3351 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3410

Query: 365  EECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARR 424
             +   +T      PI T  ++ P P  T +      PT  P  T    T    P P   +
Sbjct: 3411 TQTPTTT------PITTTTTVTPTPTPTGT----QTPTTTPITTTTTVT--PTPTPTGTQ 3458

Query: 425  PPSGGPCQAERDDSDCEEPIEASGFASGEVFDSS----LPPTDDEDFYTTFPLVTDRTTL 480
             P+  P       +    P       +  +  ++     P        TT P+ T  T  
Sbjct: 3459 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV- 3517

Query: 481  LSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGP-GAP 539
                 P P P   T   T  P        P P  P G         P+     + P   P
Sbjct: 3518 ----TPTPTPT-GTQTPTTTPITTTTTVTPTPT-PTG--TQTPTTTPITTTTTVTPTPTP 3569

Query: 540  TSFEPRRPPPLRPGVTSAPGFPHLPTANPTG 570
            T  +     P+    T        PT  PTG
Sbjct: 3570 TGTQTPTTTPITTTTTVT------PTPTPTG 3594



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 62/271 (22%), Positives = 86/271 (31%), Gaps = 33/271 (12%)

Query: 306  TTATTLLADMATTIMET-TTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDL 364
            TT TT+      T  +T TTT  TTTT    +PT   + T  T  +   +   P+     
Sbjct: 3558 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3617

Query: 365  EECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARR 424
             +   +T      PI T  ++ P P  T +      PT  P  T    T    P P   +
Sbjct: 3618 TQTPTTT------PITTTTTVTPTPTPTGT----QTPTTTPITTTTTVT--PTPTPTGTQ 3665

Query: 425  PPSGGPCQAERDDSDCEEPIEASGFASGEVFDSS----LPPTDDEDFYTTFPLVTDRTTL 480
             P+  P       +    P       +  +  ++     P        TT P+ T  T  
Sbjct: 3666 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV- 3724

Query: 481  LSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGP-GAP 539
                 P P P   T   T  P        P P  P G         P+     + P   P
Sbjct: 3725 ----TPTPTPT-GTQTPTTTPITTTTTVTPTPT-PTG--TQTPTTTPITTTTTVTPTPTP 3776

Query: 540  TSFEPRRPPPLRPGVTSAPGFPHLPTANPTG 570
            T  +     P+    T        PT  PTG
Sbjct: 3777 TGTQTPTTTPITTTTTVT------PTPTPTG 3801



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 62/271 (22%), Positives = 86/271 (31%), Gaps = 33/271 (12%)

Query: 306  TTATTLLADMATTIMET-TTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDL 364
            TT TT+      T  +T TTT  TTTT    +PT   + T  T  +   +   P+     
Sbjct: 3765 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3824

Query: 365  EECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARR 424
             +   +T      PI T  ++ P P  T +      PT  P  T    T    P P   +
Sbjct: 3825 TQTPTTT------PITTTTTVTPTPTPTGT----QTPTTTPITTTTTVT--PTPTPTGTQ 3872

Query: 425  PPSGGPCQAERDDSDCEEPIEASGFASGEVFDSS----LPPTDDEDFYTTFPLVTDRTTL 480
             P+  P       +    P       +  +  ++     P        TT P+ T  T  
Sbjct: 3873 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV- 3931

Query: 481  LSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGP-GAP 539
                 P P P   T   T  P        P P  P G         P+     + P   P
Sbjct: 3932 ----TPTPTPT-GTQTPTTTPITTTTTVTPTPT-PTG--TQTPTTTPITTTTTVTPTPTP 3983

Query: 540  TSFEPRRPPPLRPGVTSAPGFPHLPTANPTG 570
            T  +     P+    T        PT  PTG
Sbjct: 3984 TGTQTPTTTPITTTTTVT------PTPTPTG 4008



 Score = 33.5 bits (75), Expect = 0.65
 Identities = 61/270 (22%), Positives = 84/270 (31%), Gaps = 35/270 (12%)

Query: 306  TTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDLE 365
            TT TT   +  T     TTT  TTTT    +PT   + T  T  +   +   P+      
Sbjct: 1883 TTMTTTTTENPTP---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 1939

Query: 366  ECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARRP 425
            +   +T      PI T  ++ P P  T +      PT  P  T    T    P P   + 
Sbjct: 1940 QTPTTT------PITTTTTVTPTPTPTGT----QTPTTTPITTTTTVT--PTPTPTGTQT 1987

Query: 426  PSGGPCQAERDDSDCEEPIEASGFASGEVFDSS----LPPTDDEDFYTTFPLVTDRTTLL 481
            P+  P       +    P       +  +  ++     P        TT P+ T  T   
Sbjct: 1988 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-- 2045

Query: 482  SPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGP-GAPT 540
                P P P   T   T  P        P P  P G         P+     + P   PT
Sbjct: 2046 ---TPTPTPT-GTQTPTTTPITTTTTVTPTPT-PTG--TQTPTTTPITTTTTVTPTPTPT 2098

Query: 541  SFEPRRPPPLRPGVTSAPGFPHLPTANPTG 570
              +     P+    T        PT  PTG
Sbjct: 2099 GTQTPTTTPITTTTTVT------PTPTPTG 2122


>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
            potassium channel 4 [Homo sapiens]
          Length = 1203

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 77/279 (27%), Positives = 102/279 (36%), Gaps = 33/279 (11%)

Query: 286  RTEGHL-RLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTT 344
            +T  HL RL    PS L SA   ++    D  ++       +A  +   G SP L  S++
Sbjct: 821  QTPRHLKRLQSLIPSALGSASPASSPSQVDTPSSSSFHIQQLAGFSAPAGLSPLLPSSSS 880

Query: 345  QNTDDLLVA-SAECPSDD------EDLEECEPSTGGELILPIITEDS--LDPPPVATRSP 395
                    + SA  PS                + GG L     + DS  L P     RSP
Sbjct: 881  SPPPGACGSPSAPTPSAGVAATTIAGFGHFHKALGGSLS----SSDSPLLTPLQPGARSP 936

Query: 396  FVPPPPTFYPFLTG-VGATQDTLPPPAARRPPSGGPCQAERDDSDCEEPIEASGFASGEV 454
                P    P   G +G  +  LPPP + R PS  P Q  +   +      + G A+G +
Sbjct: 937  QAAQPSPAPPGARGGLGLPEHFLPPPPSSRSPSSSPGQLGQPPGEL-----SLGLATGPL 991

Query: 455  FDSSLPPTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNL 514
                 PP   E       LV   +   SP    PR  L   G +  P   F PSAP    
Sbjct: 992  STPETPPRQPE----PPSLVAGASGGASPVGFTPRGGLSPPGHSPGPPRTF-PSAP---- 1042

Query: 515  PAGKMNHRDPLQPLLENPPLGPGAPTSFEPRRPPPLRPG 553
            P    +H   L P   +PP     P   + R  PPL PG
Sbjct: 1043 PRASGSHGSLLLPPASSPP----PPQVPQRRGTPPLTPG 1077



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 15/31 (48%), Positives = 16/31 (51%), Gaps = 3/31 (9%)

Query: 2   PPGGSGPGGCPRRPPALAGPLPPPPPPPPPP 32
           PPG +     P RP A A P   PPPP  PP
Sbjct: 145 PPGLAAE---PERPGASAQPAASPPPPQQPP 172


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 69/297 (23%), Positives = 97/297 (32%), Gaps = 34/297 (11%)

Query: 296 EGPSVLLSAETTATTLLADMATTIMETTTTM--ATTTTRRGRSPTLRDSTTQNTDDLLVA 353
           +GP++    E T TT     +TT  E T T   +  TT +  +PT   S      +    
Sbjct: 206 KGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT 265

Query: 354 SAECPSDDEDLEECEPSTGGELILPIITEDSLDPPPVATRS-PFVP--PPPTF--YPFLT 408
           + + P+     E    +T              +P P  T+S P  P  P PT    P  T
Sbjct: 266 TTKEPAPTTPKEPAPTTTK-------------EPAPTTTKSAPTTPKEPAPTTPKKPAPT 312

Query: 409 GVGATQDTLPP-PAARRPPSGGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDF 467
                  T P  P    P    P   E   +  +EP   +             PT  ++ 
Sbjct: 313 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE- 371

Query: 468 YTTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQP 527
               P  T   +  +P++PAP         T  P      SAP           ++P   
Sbjct: 372 --PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 429

Query: 528 LLENP-PLGPGAPTSFEPRRPPPLRPGVTS-------APGFPHLPTANPTGPGERGP 576
             + P P  P  P    P+ P P  P   +       AP  P  P   PT P E  P
Sbjct: 430 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA--PTTPKETAP 484



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 74/304 (24%), Positives = 106/304 (34%), Gaps = 35/304 (11%)

Query: 298 PSVLLSAETTATTLLADMATTIMET--TTTMATTTTRRGRSPTLRDSTTQNTDDLLVASA 355
           PS+  +++T+  T L     T +ET  TTT    T+  G+  T     TQ+ +    ++ 
Sbjct: 128 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK--TSAK 185

Query: 356 ECPSDDEDLEECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQD 415
           +     + L +  P        P +T    +P P   + P    P    P  T + +   
Sbjct: 186 DLAPTSKVLAKPTPKAETTTKGPALTTPK-EPTPTTPKEPASTTPKE--PTPTTIKSAPT 242

Query: 416 TLPPPAARRPPSGGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVT 475
           T   PA     S      E   +  +EP   +             PT  +   TT P   
Sbjct: 243 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT-PKEP 301

Query: 476 DRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLG 535
             TT   P+KPAP     T     AP     P  P P  P      ++P     E  P  
Sbjct: 302 APTT---PKKPAP-----TTPKEPAPTT---PKEPTPTTP------KEPAPTTKEPAPTT 344

Query: 536 PGAPTSFEPRRPPPLRPGVTSAPGFPHLPT------ANPTGPGERGP---PGAVEVIRES 586
           P  P    P++P P  P    AP  P  P        +PT P E  P     A    +E 
Sbjct: 345 PKEPAPTAPKKPAPTTP-KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 403

Query: 587 SSTT 590
           + TT
Sbjct: 404 APTT 407



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 64/307 (20%), Positives = 89/307 (28%), Gaps = 73/307 (23%)

Query: 303 SAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSDDE 362
           +A TT   L       +  TT      TT    +PT  +  T  T +    +    +   
Sbjct: 482 TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN 541

Query: 363 DLEECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAA 422
             +E  P+T  E            P P   + P    P    P  T  G    TL  PA 
Sbjct: 542 TPKEPAPTTPKE------------PAPTTPKEPAPTTPKETAP-TTPKGTAPTTLKEPAP 588

Query: 423 RRPPSGGPCQA------ERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTD 476
             P    P +       E   + C++P   +   +         PT  ++   T P  T 
Sbjct: 589 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 648

Query: 477 RTTL-----LSPRKPAPRP--NLRTDGATGAPGVLFAPSAPAPNLPAGKMN--------- 520
            TTL      +P+KPAP+      T G T       AP+ P    P              
Sbjct: 649 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 708

Query: 521 ---------------------------HR-----------DPLQPLLENPPLGPGAPTSF 542
                                      H+           +P    LEN P  PG PT+ 
Sbjct: 709 APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTK 768

Query: 543 EPRRPPP 549
            P    P
Sbjct: 769 TPAATKP 775



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 72/301 (23%), Positives = 100/301 (33%), Gaps = 41/301 (13%)

Query: 295 GEGPSVLLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQNTDDLLVAS 354
           G  P+ L   E   TT        +  TTT   T+TT    +PT    T   T     A 
Sbjct: 646 GTAPTTL--KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE-PAP 702

Query: 355 AECPSDDEDLEECEPSTGGELILPIITEDSLD---PPPVATRSPFVPPPPTFY---PFLT 408
                      E  P T  E+  P  T++       P  +T      P P      P   
Sbjct: 703 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 762

Query: 409 GVGATQDTLPPPAARRPPSGGPCQ---AERDDSDCEEPIEASGFASGEVFDSSLPPTDDE 465
           GV  T+     PAA +P      +    ERD     E   A+   + E   ++   T+ +
Sbjct: 763 GVPTTKT----PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESK 818

Query: 466 DFYTT-------------FPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAP 512
              TT             F + T +TT L+P+    +  + T      P     P   A 
Sbjct: 819 ITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRAT 878

Query: 513 NLPAGKMNHRDPLQPLLENPPLGPGAPTSF-EPRRPPPLR-PGVTSAPG--FPHLPTANP 568
           N  A          P  + P   P  PTS  +P+  P +R P  T  P      +P  NP
Sbjct: 879 NSKA--------TTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNP 930

Query: 569 T 569
           T
Sbjct: 931 T 931



 Score = 33.9 bits (76), Expect = 0.50
 Identities = 64/269 (23%), Positives = 87/269 (32%), Gaps = 32/269 (11%)

Query: 322 TTTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGGELILPIIT 381
           TTT   + TT +  +PT   S    T +   A     S     +E  P+T  E   P  T
Sbjct: 375 TTTKEPSPTTPKEPAPTTTKSAPTTTKE--PAPTTTKSAPTTPKEPSPTTTKE---PAPT 429

Query: 382 EDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARRPPSGGPCQAERDDSDCE 441
               +P P   + P    P    P  T       T   PA   P    P   +       
Sbjct: 430 TPK-EPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 487

Query: 442 EPIEASGFASGEVFDSSLP----PTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGA 497
           + +  +   + E    + P    PT  E+   T P   +  T  +P +PAP     T   
Sbjct: 488 KKLTPT---TPEKLAPTTPEKPAPTTPEELAPTTP---EEPTPTTPEEPAP-----TTPK 536

Query: 498 TGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGP--GAPTSFE------PRRPPP 549
             AP     P+   P  PA             E  P  P   APT+ +      P++P P
Sbjct: 537 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 596

Query: 550 --LRPGVTSAPGFPHLPTANPTGPGERGP 576
             L P  T  P         PT P    P
Sbjct: 597 KELAPTTTKEPTSTTCDKPAPTTPKGTAP 625


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 69/297 (23%), Positives = 97/297 (32%), Gaps = 34/297 (11%)

Query: 296 EGPSVLLSAETTATTLLADMATTIMETTTTM--ATTTTRRGRSPTLRDSTTQNTDDLLVA 353
           +GP++    E T TT     +TT  E T T   +  TT +  +PT   S      +    
Sbjct: 247 KGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT 306

Query: 354 SAECPSDDEDLEECEPSTGGELILPIITEDSLDPPPVATRS-PFVP--PPPTF--YPFLT 408
           + + P+     E    +T              +P P  T+S P  P  P PT    P  T
Sbjct: 307 TTKEPAPTTPKEPAPTTTK-------------EPAPTTTKSAPTTPKEPAPTTPKKPAPT 353

Query: 409 GVGATQDTLPP-PAARRPPSGGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDF 467
                  T P  P    P    P   E   +  +EP   +             PT  ++ 
Sbjct: 354 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE- 412

Query: 468 YTTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQP 527
               P  T   +  +P++PAP         T  P      SAP           ++P   
Sbjct: 413 --PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 470

Query: 528 LLENP-PLGPGAPTSFEPRRPPPLRPGVTS-------APGFPHLPTANPTGPGERGP 576
             + P P  P  P    P+ P P  P   +       AP  P  P   PT P E  P
Sbjct: 471 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA--PTTPKETAP 525



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 74/304 (24%), Positives = 106/304 (34%), Gaps = 35/304 (11%)

Query: 298 PSVLLSAETTATTLLADMATTIMET--TTTMATTTTRRGRSPTLRDSTTQNTDDLLVASA 355
           PS+  +++T+  T L     T +ET  TTT    T+  G+  T     TQ+ +    ++ 
Sbjct: 169 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK--TSAK 226

Query: 356 ECPSDDEDLEECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQD 415
           +     + L +  P        P +T    +P P   + P    P    P  T + +   
Sbjct: 227 DLAPTSKVLAKPTPKAETTTKGPALTTPK-EPTPTTPKEPASTTPKE--PTPTTIKSAPT 283

Query: 416 TLPPPAARRPPSGGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVT 475
           T   PA     S      E   +  +EP   +             PT  +   TT P   
Sbjct: 284 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT-PKEP 342

Query: 476 DRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLG 535
             TT   P+KPAP     T     AP     P  P P  P      ++P     E  P  
Sbjct: 343 APTT---PKKPAP-----TTPKEPAPTT---PKEPTPTTP------KEPAPTTKEPAPTT 385

Query: 536 PGAPTSFEPRRPPPLRPGVTSAPGFPHLPT------ANPTGPGERGP---PGAVEVIRES 586
           P  P    P++P P  P    AP  P  P        +PT P E  P     A    +E 
Sbjct: 386 PKEPAPTAPKKPAPTTP-KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 444

Query: 587 SSTT 590
           + TT
Sbjct: 445 APTT 448



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 64/307 (20%), Positives = 89/307 (28%), Gaps = 73/307 (23%)

Query: 303 SAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSDDE 362
           +A TT   L       +  TT      TT    +PT  +  T  T +    +    +   
Sbjct: 523 TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN 582

Query: 363 DLEECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAA 422
             +E  P+T  E            P P   + P    P    P  T  G    TL  PA 
Sbjct: 583 TPKEPAPTTPKE------------PAPTTPKEPAPTTPKETAP-TTPKGTAPTTLKEPAP 629

Query: 423 RRPPSGGPCQA------ERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTD 476
             P    P +       E   + C++P   +   +         PT  ++   T P  T 
Sbjct: 630 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 689

Query: 477 RTTL-----LSPRKPAPRP--NLRTDGATGAPGVLFAPSAPAPNLPAGKMN--------- 520
            TTL      +P+KPAP+      T G T       AP+ P    P              
Sbjct: 690 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 749

Query: 521 ---------------------------HR-----------DPLQPLLENPPLGPGAPTSF 542
                                      H+           +P    LEN P  PG PT+ 
Sbjct: 750 APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTK 809

Query: 543 EPRRPPP 549
            P    P
Sbjct: 810 TPAATKP 816



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 72/301 (23%), Positives = 100/301 (33%), Gaps = 41/301 (13%)

Query: 295 GEGPSVLLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQNTDDLLVAS 354
           G  P+ L   E   TT        +  TTT   T+TT    +PT    T   T     A 
Sbjct: 687 GTAPTTL--KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE-PAP 743

Query: 355 AECPSDDEDLEECEPSTGGELILPIITEDSLD---PPPVATRSPFVPPPPTFY---PFLT 408
                      E  P T  E+  P  T++       P  +T      P P      P   
Sbjct: 744 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 803

Query: 409 GVGATQDTLPPPAARRPPSGGPCQ---AERDDSDCEEPIEASGFASGEVFDSSLPPTDDE 465
           GV  T+     PAA +P      +    ERD     E   A+   + E   ++   T+ +
Sbjct: 804 GVPTTKT----PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESK 859

Query: 466 DFYTT-------------FPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAP 512
              TT             F + T +TT L+P+    +  + T      P     P   A 
Sbjct: 860 ITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRAT 919

Query: 513 NLPAGKMNHRDPLQPLLENPPLGPGAPTSF-EPRRPPPLR-PGVTSAPG--FPHLPTANP 568
           N  A          P  + P   P  PTS  +P+  P +R P  T  P      +P  NP
Sbjct: 920 NSKA--------TTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNP 971

Query: 569 T 569
           T
Sbjct: 972 T 972



 Score = 33.9 bits (76), Expect = 0.50
 Identities = 64/269 (23%), Positives = 87/269 (32%), Gaps = 32/269 (11%)

Query: 322 TTTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGGELILPIIT 381
           TTT   + TT +  +PT   S    T +   A     S     +E  P+T  E   P  T
Sbjct: 416 TTTKEPSPTTPKEPAPTTTKSAPTTTKE--PAPTTTKSAPTTPKEPSPTTTKE---PAPT 470

Query: 382 EDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARRPPSGGPCQAERDDSDCE 441
               +P P   + P    P    P  T       T   PA   P    P   +       
Sbjct: 471 TPK-EPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 528

Query: 442 EPIEASGFASGEVFDSSLP----PTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGA 497
           + +  +   + E    + P    PT  E+   T P   +  T  +P +PAP     T   
Sbjct: 529 KKLTPT---TPEKLAPTTPEKPAPTTPEELAPTTP---EEPTPTTPEEPAP-----TTPK 577

Query: 498 TGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGP--GAPTSFE------PRRPPP 549
             AP     P+   P  PA             E  P  P   APT+ +      P++P P
Sbjct: 578 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 637

Query: 550 --LRPGVTSAPGFPHLPTANPTGPGERGP 576
             L P  T  P         PT P    P
Sbjct: 638 KELAPTTTKEPTSTTCDKPAPTTPKGTAP 666


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 69/297 (23%), Positives = 97/297 (32%), Gaps = 34/297 (11%)

Query: 296 EGPSVLLSAETTATTLLADMATTIMETTTTM--ATTTTRRGRSPTLRDSTTQNTDDLLVA 353
           +GP++    E T TT     +TT  E T T   +  TT +  +PT   S      +    
Sbjct: 299 KGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT 358

Query: 354 SAECPSDDEDLEECEPSTGGELILPIITEDSLDPPPVATRS-PFVP--PPPTF--YPFLT 408
           + + P+     E    +T              +P P  T+S P  P  P PT    P  T
Sbjct: 359 TTKEPAPTTPKEPAPTTTK-------------EPAPTTTKSAPTTPKEPAPTTPKKPAPT 405

Query: 409 GVGATQDTLPP-PAARRPPSGGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDF 467
                  T P  P    P    P   E   +  +EP   +             PT  ++ 
Sbjct: 406 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE- 464

Query: 468 YTTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQP 527
               P  T   +  +P++PAP         T  P      SAP           ++P   
Sbjct: 465 --PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 522

Query: 528 LLENP-PLGPGAPTSFEPRRPPPLRPGVTS-------APGFPHLPTANPTGPGERGP 576
             + P P  P  P    P+ P P  P   +       AP  P  P   PT P E  P
Sbjct: 523 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA--PTTPKETAP 577



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 74/304 (24%), Positives = 106/304 (34%), Gaps = 35/304 (11%)

Query: 298 PSVLLSAETTATTLLADMATTIMET--TTTMATTTTRRGRSPTLRDSTTQNTDDLLVASA 355
           PS+  +++T+  T L     T +ET  TTT    T+  G+  T     TQ+ +    ++ 
Sbjct: 221 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK--TSAK 278

Query: 356 ECPSDDEDLEECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQD 415
           +     + L +  P        P +T    +P P   + P    P    P  T + +   
Sbjct: 279 DLAPTSKVLAKPTPKAETTTKGPALTTPK-EPTPTTPKEPASTTPKE--PTPTTIKSAPT 335

Query: 416 TLPPPAARRPPSGGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVT 475
           T   PA     S      E   +  +EP   +             PT  +   TT P   
Sbjct: 336 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT-PKEP 394

Query: 476 DRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLG 535
             TT   P+KPAP     T     AP     P  P P  P      ++P     E  P  
Sbjct: 395 APTT---PKKPAP-----TTPKEPAPTT---PKEPTPTTP------KEPAPTTKEPAPTT 437

Query: 536 PGAPTSFEPRRPPPLRPGVTSAPGFPHLPT------ANPTGPGERGP---PGAVEVIRES 586
           P  P    P++P P  P    AP  P  P        +PT P E  P     A    +E 
Sbjct: 438 PKEPAPTAPKKPAPTTP-KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 496

Query: 587 SSTT 590
           + TT
Sbjct: 497 APTT 500



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 64/307 (20%), Positives = 89/307 (28%), Gaps = 73/307 (23%)

Query: 303 SAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSDDE 362
           +A TT   L       +  TT      TT    +PT  +  T  T +    +    +   
Sbjct: 575 TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN 634

Query: 363 DLEECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAA 422
             +E  P+T  E            P P   + P    P    P  T  G    TL  PA 
Sbjct: 635 TPKEPAPTTPKE------------PAPTTPKEPAPTTPKETAP-TTPKGTAPTTLKEPAP 681

Query: 423 RRPPSGGPCQA------ERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTD 476
             P    P +       E   + C++P   +   +         PT  ++   T P  T 
Sbjct: 682 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 741

Query: 477 RTTL-----LSPRKPAPRP--NLRTDGATGAPGVLFAPSAPAPNLPAGKMN--------- 520
            TTL      +P+KPAP+      T G T       AP+ P    P              
Sbjct: 742 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 801

Query: 521 ---------------------------HR-----------DPLQPLLENPPLGPGAPTSF 542
                                      H+           +P    LEN P  PG PT+ 
Sbjct: 802 APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTK 861

Query: 543 EPRRPPP 549
            P    P
Sbjct: 862 TPAATKP 868



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 72/301 (23%), Positives = 100/301 (33%), Gaps = 41/301 (13%)

Query: 295  GEGPSVLLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQNTDDLLVAS 354
            G  P+ L   E   TT        +  TTT   T+TT    +PT    T   T     A 
Sbjct: 739  GTAPTTL--KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE-PAP 795

Query: 355  AECPSDDEDLEECEPSTGGELILPIITEDSLD---PPPVATRSPFVPPPPTFY---PFLT 408
                       E  P T  E+  P  T++       P  +T      P P      P   
Sbjct: 796  TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 855

Query: 409  GVGATQDTLPPPAARRPPSGGPCQ---AERDDSDCEEPIEASGFASGEVFDSSLPPTDDE 465
            GV  T+     PAA +P      +    ERD     E   A+   + E   ++   T+ +
Sbjct: 856  GVPTTKT----PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESK 911

Query: 466  DFYTT-------------FPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAP 512
               TT             F + T +TT L+P+    +  + T      P     P   A 
Sbjct: 912  ITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRAT 971

Query: 513  NLPAGKMNHRDPLQPLLENPPLGPGAPTSF-EPRRPPPLR-PGVTSAPG--FPHLPTANP 568
            N  A          P  + P   P  PTS  +P+  P +R P  T  P      +P  NP
Sbjct: 972  NSKA--------TTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNP 1023

Query: 569  T 569
            T
Sbjct: 1024 T 1024



 Score = 33.9 bits (76), Expect = 0.50
 Identities = 64/269 (23%), Positives = 87/269 (32%), Gaps = 32/269 (11%)

Query: 322 TTTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGGELILPIIT 381
           TTT   + TT +  +PT   S    T +   A     S     +E  P+T  E   P  T
Sbjct: 468 TTTKEPSPTTPKEPAPTTTKSAPTTTKE--PAPTTTKSAPTTPKEPSPTTTKE---PAPT 522

Query: 382 EDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARRPPSGGPCQAERDDSDCE 441
               +P P   + P    P    P  T       T   PA   P    P   +       
Sbjct: 523 TPK-EPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 580

Query: 442 EPIEASGFASGEVFDSSLP----PTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGA 497
           + +  +   + E    + P    PT  E+   T P   +  T  +P +PAP     T   
Sbjct: 581 KKLTPT---TPEKLAPTTPEKPAPTTPEELAPTTP---EEPTPTTPEEPAP-----TTPK 629

Query: 498 TGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGP--GAPTSFE------PRRPPP 549
             AP     P+   P  PA             E  P  P   APT+ +      P++P P
Sbjct: 630 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 689

Query: 550 --LRPGVTSAPGFPHLPTANPTGPGERGP 576
             L P  T  P         PT P    P
Sbjct: 690 KELAPTTTKEPTSTTCDKPAPTTPKGTAP 718


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 69/297 (23%), Positives = 97/297 (32%), Gaps = 34/297 (11%)

Query: 296 EGPSVLLSAETTATTLLADMATTIMETTTTM--ATTTTRRGRSPTLRDSTTQNTDDLLVA 353
           +GP++    E T TT     +TT  E T T   +  TT +  +PT   S      +    
Sbjct: 340 KGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT 399

Query: 354 SAECPSDDEDLEECEPSTGGELILPIITEDSLDPPPVATRS-PFVP--PPPTF--YPFLT 408
           + + P+     E    +T              +P P  T+S P  P  P PT    P  T
Sbjct: 400 TTKEPAPTTPKEPAPTTTK-------------EPAPTTTKSAPTTPKEPAPTTPKKPAPT 446

Query: 409 GVGATQDTLPP-PAARRPPSGGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDF 467
                  T P  P    P    P   E   +  +EP   +             PT  ++ 
Sbjct: 447 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE- 505

Query: 468 YTTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQP 527
               P  T   +  +P++PAP         T  P      SAP           ++P   
Sbjct: 506 --PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 563

Query: 528 LLENP-PLGPGAPTSFEPRRPPPLRPGVTS-------APGFPHLPTANPTGPGERGP 576
             + P P  P  P    P+ P P  P   +       AP  P  P   PT P E  P
Sbjct: 564 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA--PTTPKETAP 618



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 74/304 (24%), Positives = 106/304 (34%), Gaps = 35/304 (11%)

Query: 298 PSVLLSAETTATTLLADMATTIMET--TTTMATTTTRRGRSPTLRDSTTQNTDDLLVASA 355
           PS+  +++T+  T L     T +ET  TTT    T+  G+  T     TQ+ +    ++ 
Sbjct: 262 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK--TSAK 319

Query: 356 ECPSDDEDLEECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQD 415
           +     + L +  P        P +T    +P P   + P    P    P  T + +   
Sbjct: 320 DLAPTSKVLAKPTPKAETTTKGPALTTPK-EPTPTTPKEPASTTPKE--PTPTTIKSAPT 376

Query: 416 TLPPPAARRPPSGGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVT 475
           T   PA     S      E   +  +EP   +             PT  +   TT P   
Sbjct: 377 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT-PKEP 435

Query: 476 DRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLG 535
             TT   P+KPAP     T     AP     P  P P  P      ++P     E  P  
Sbjct: 436 APTT---PKKPAP-----TTPKEPAPTT---PKEPTPTTP------KEPAPTTKEPAPTT 478

Query: 536 PGAPTSFEPRRPPPLRPGVTSAPGFPHLPT------ANPTGPGERGP---PGAVEVIRES 586
           P  P    P++P P  P    AP  P  P        +PT P E  P     A    +E 
Sbjct: 479 PKEPAPTAPKKPAPTTP-KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 537

Query: 587 SSTT 590
           + TT
Sbjct: 538 APTT 541



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 64/307 (20%), Positives = 89/307 (28%), Gaps = 73/307 (23%)

Query: 303 SAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSDDE 362
           +A TT   L       +  TT      TT    +PT  +  T  T +    +    +   
Sbjct: 616 TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN 675

Query: 363 DLEECEPSTGGELILPIITEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAA 422
             +E  P+T  E            P P   + P    P    P  T  G    TL  PA 
Sbjct: 676 TPKEPAPTTPKE------------PAPTTPKEPAPTTPKETAP-TTPKGTAPTTLKEPAP 722

Query: 423 RRPPSGGPCQA------ERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTD 476
             P    P +       E   + C++P   +   +         PT  ++   T P  T 
Sbjct: 723 TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 782

Query: 477 RTTL-----LSPRKPAPRP--NLRTDGATGAPGVLFAPSAPAPNLPAGKMN--------- 520
            TTL      +P+KPAP+      T G T       AP+ P    P              
Sbjct: 783 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 842

Query: 521 ---------------------------HR-----------DPLQPLLENPPLGPGAPTSF 542
                                      H+           +P    LEN P  PG PT+ 
Sbjct: 843 APTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTK 902

Query: 543 EPRRPPP 549
            P    P
Sbjct: 903 TPAATKP 909



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 72/301 (23%), Positives = 100/301 (33%), Gaps = 41/301 (13%)

Query: 295  GEGPSVLLSAETTATTLLADMATTIMETTTTMATTTTRRGRSPTLRDSTTQNTDDLLVAS 354
            G  P+ L   E   TT        +  TTT   T+TT    +PT    T   T     A 
Sbjct: 780  GTAPTTL--KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE-PAP 836

Query: 355  AECPSDDEDLEECEPSTGGELILPIITEDSLD---PPPVATRSPFVPPPPTFY---PFLT 408
                       E  P T  E+  P  T++       P  +T      P P      P   
Sbjct: 837  TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 896

Query: 409  GVGATQDTLPPPAARRPPSGGPCQ---AERDDSDCEEPIEASGFASGEVFDSSLPPTDDE 465
            GV  T+     PAA +P      +    ERD     E   A+   + E   ++   T+ +
Sbjct: 897  GVPTTKT----PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESK 952

Query: 466  DFYTT-------------FPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAP 512
               TT             F + T +TT L+P+    +  + T      P     P   A 
Sbjct: 953  ITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRAT 1012

Query: 513  NLPAGKMNHRDPLQPLLENPPLGPGAPTSF-EPRRPPPLR-PGVTSAPG--FPHLPTANP 568
            N  A          P  + P   P  PTS  +P+  P +R P  T  P      +P  NP
Sbjct: 1013 NSKA--------TTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNP 1064

Query: 569  T 569
            T
Sbjct: 1065 T 1065



 Score = 33.9 bits (76), Expect = 0.50
 Identities = 64/269 (23%), Positives = 87/269 (32%), Gaps = 32/269 (11%)

Query: 322 TTTTMATTTTRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGGELILPIIT 381
           TTT   + TT +  +PT   S    T +   A     S     +E  P+T  E   P  T
Sbjct: 509 TTTKEPSPTTPKEPAPTTTKSAPTTTKE--PAPTTTKSAPTTPKEPSPTTTKE---PAPT 563

Query: 382 EDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARRPPSGGPCQAERDDSDCE 441
               +P P   + P    P    P  T       T   PA   P    P   +       
Sbjct: 564 TPK-EPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 621

Query: 442 EPIEASGFASGEVFDSSLP----PTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGA 497
           + +  +   + E    + P    PT  E+   T P   +  T  +P +PAP     T   
Sbjct: 622 KKLTPT---TPEKLAPTTPEKPAPTTPEELAPTTP---EEPTPTTPEEPAP-----TTPK 670

Query: 498 TGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGP--GAPTSFE------PRRPPP 549
             AP     P+   P  PA             E  P  P   APT+ +      P++P P
Sbjct: 671 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 730

Query: 550 --LRPGVTSAPGFPHLPTANPTGPGERGP 576
             L P  T  P         PT P    P
Sbjct: 731 KELAPTTTKEPTSTTCDKPAPTTPKGTAP 759


>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
          Length = 962

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 54/207 (26%), Positives = 70/207 (33%), Gaps = 19/207 (9%)

Query: 381 TEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQDTLPPPAARRPPSGGPCQAERDDSD- 439
           T +  +P    T     P PP   P     G  QD   PPA       GPC    D ++ 
Sbjct: 338 TPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPA-------GPCAPATDKAEE 390

Query: 440 --CEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGA 497
             C     AS F +      + PP  D    +  P   D      P++  P P +  D  
Sbjct: 391 VVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEE 450

Query: 498 TGAPGVLFAPSAPA---PNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEPRRPPPLRPGV 554
            G PG    P   A   P   AG    R   +P     P  P AP S    RP     G 
Sbjct: 451 KGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAP-SPPAPKSCLKHRPAAASEGP 509

Query: 555 TSAPGFPHLPTANPTGPGERGPPGAVE 581
            ++P     P A    P     PG+++
Sbjct: 510 AASP-----PLAAAESPPVEPGPGSLD 531



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 41/164 (25%), Positives = 59/164 (35%), Gaps = 33/164 (20%)

Query: 418 PPPAARRPPSGGPCQAERDDSDCEE----PIEA-SGFASGEVFDSSLPPTDDEDFYTTFP 472
           P  AA  P +  PC A ++ +  E+    P++  S   S +  D +         Y+   
Sbjct: 654 PQEAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEV 713

Query: 473 LVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENP 532
            +    T+L   +  P          G    L    AP+     GK   R P +PL   P
Sbjct: 714 RLERSLTVLPKEEKCP---------LGTAPALRGTRAPSDQ---GKGKARPP-EPLSSKP 760

Query: 533 PLGPGAPTSFEPRRPPPLRPGVTSAPGFPHLPTANPTGPGERGP 576
           PL         PR+P      +  +   PH P     GPGER P
Sbjct: 761 PL---------PRKP------LLQSFTLPHQPAPPDAGPGEREP 789


>gi|63025220 ring finger protein 215 [Homo sapiens]
          Length = 377

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 27/45 (60%), Positives = 27/45 (60%), Gaps = 1/45 (2%)

Query: 12 PRRPPALAGPLPPPPPPPPPPLLPLLPLLLLLLLGAAEGARVSSS 56
          P   PAL  P PPPPPPPP PLL LLPLL L L  A  GA    S
Sbjct: 3  PAARPALRSP-PPPPPPPPSPLLLLLPLLPLWLGLAGPGAAADGS 46


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 34/105 (32%), Positives = 41/105 (39%), Gaps = 11/105 (10%)

Query: 486  PAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHR---------DPLQPLLENPPLGP 536
            P  + +    G  G PG   AP AP P  PAGK   R          P+ P+    P GP
Sbjct: 1030 PGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGP 1089

Query: 537  GAPTSFEPRRPPPLRPGVTSAPGFPHL--PTANPTGPGERGPPGA 579
              P   +         G+    GF  L  P   P  PGE+GP GA
Sbjct: 1090 QGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGA 1134



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 51/160 (31%), Positives = 57/160 (35%), Gaps = 23/160 (14%)

Query: 436 DDSDCEEPIEASG--FASGEVF----DSSLPPTDDEDFYTTFPLVTDRTTLLSPRKPAPR 489
           DD  C+E     G     GE      D S  PTD E      P     T    PR PA  
Sbjct: 71  DDVICDETKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGP--KGDTGPRGPRGPAGP 128

Query: 490 PNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPL---------LENP-PLGPGAP 539
           P    DG  G PG+   P  P P  P G   +  P             +  P P+GP  P
Sbjct: 129 PG--RDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGP 186

Query: 540 TSFEPRRPPPLRPGVTSAPGFPHLPTAN-PTGPGERGPPG 578
                    P   G    PG P  P A+ P GP  RGPPG
Sbjct: 187 RGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGP--RGPPG 224



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 36/105 (34%), Positives = 41/105 (39%), Gaps = 25/105 (23%)

Query: 496 GATGAPGVLFAPSAPAPNLPAG----------KMNHRDPLQP--------LLENPPL--- 534
           GA GAPG+  AP  P    P+G          K N  +P  P          E  P+   
Sbjct: 398 GANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQ 457

Query: 535 GPGAPTSFEPRRPPPLRPGVTSAPGFPHLPTANPTGPGERGPPGA 579
           GP  P   E +R     PG T  PG    P     GPG RG PGA
Sbjct: 458 GPPGPAGEEGKRGARGEPGPTGLPG----PPGERGGPGSRGFPGA 498



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 32/97 (32%), Positives = 35/97 (36%), Gaps = 10/97 (10%)

Query: 483 PRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSF 542
           P  P P      DGATGA G       P P  PAG       +    E  P GP      
Sbjct: 313 PGAPGPAGARGNDGATGAAG------PPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGP 366

Query: 543 EPRRPPPLRPGVTSAPGFPHLPTANPTGPGERGPPGA 579
           +  R  P  PG   A G    P  NP   G+ G  GA
Sbjct: 367 QGVRGEPGPPGPAGAAG----PAGNPGADGQPGAKGA 399



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 32/95 (33%), Positives = 38/95 (40%), Gaps = 6/95 (6%)

Query: 486 PAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEPR 545
           P P  N+   GA GA G    P A      AG++    P  P     P GP  P   E  
Sbjct: 850 PGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVG---PPGPSGNAGPPGPPGPAGKEGG 906

Query: 546 RPPPLRPGVTSAPGFPHLPTANPTGP-GERGPPGA 579
           + P    G    PG   +    P GP GE+G PGA
Sbjct: 907 KGPRGETGPAGRPG--EVGPPGPPGPAGEKGSPGA 939



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 32/106 (30%), Positives = 34/106 (32%), Gaps = 23/106 (21%)

Query: 496 GATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLG----PGAPTSFEPRRPPPLR 551
           GA G  G    P  P     +G M  R P  P  +N   G    PG P    P  P   R
Sbjct: 194 GAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGAR 253

Query: 552 --PGVTSAPGF-----------------PHLPTANPTGPGERGPPG 578
             PG    PG                  P  P   P  PGE G PG
Sbjct: 254 GLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPG 299



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 31/106 (29%), Positives = 38/106 (35%), Gaps = 11/106 (10%)

Query: 482  SPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPTS 541
            +P  P P+      G  G PG       P    P+G+   + P     E  P GP  P  
Sbjct: 945  APGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPG 1004

Query: 542  FEPRRPPPLRPGVTSAPGFPHLP--TANPTGPGER------GPPGA 579
                  PP   G   APG    P    +P   G+R      GPPGA
Sbjct: 1005 L---AGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGA 1047



 Score = 34.3 bits (77), Expect = 0.38
 Identities = 41/129 (31%), Positives = 44/129 (34%), Gaps = 38/129 (29%)

Query: 482 SPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLP------AGKMNHRDPLQPLLENPPLG 535
           SP  P P      DG TG PG       P P  P      AG M    P     E    G
Sbjct: 543 SPGSPGP------DGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAG 596

Query: 536 ----PGAPTSFEPR----------RPPPLRP-------GVTSAPGFPHLP-TANPTG--- 570
               PG P +  P            P P  P       G   +PGF  LP  A P G   
Sbjct: 597 ERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAG 656

Query: 571 -PGERGPPG 578
            PGE+G PG
Sbjct: 657 KPGEQGVPG 665



 Score = 33.5 bits (75), Expect = 0.65
 Identities = 18/37 (48%), Positives = 18/37 (48%), Gaps = 5/37 (13%)

Query: 2   PPGGSGPGGCPRR-----PPALAGPLPPPPPPPPPPL 33
           P G  GP G P R      P L GP  PP PP PP L
Sbjct: 119 PRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGL 155



 Score = 33.5 bits (75), Expect = 0.65
 Identities = 33/106 (31%), Positives = 37/106 (34%), Gaps = 26/106 (24%)

Query: 495 DGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSF--------EPRR 546
           DG+ G  GV        P  PAG    +       E+ P GP  PT          EP  
Sbjct: 754 DGSPGKDGVRGLTGPIGPPGPAGAPGDKG------ESGPSGPAGPTGARGAPGDRGEPGP 807

Query: 547 PPPL----RPGVTSAPGFPHLP-------TANPTGP-GERGPPGAV 580
           P P      PG    PG    P        A P GP G  GPPG +
Sbjct: 808 PGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPI 853



 Score = 32.0 bits (71), Expect = 1.9
 Identities = 32/112 (28%), Positives = 38/112 (33%), Gaps = 30/112 (26%)

Query: 496 GATGAPGVLFAPSAPAPNLPAGKMNHRDP---LQPLLENPPLGPGAPTSFEPRRPPPLRP 552
           G  G PG       P P  PAGK   + P     P      +GP  P      +  P   
Sbjct: 881 GRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGAD 940

Query: 553 GVTSAP------------------------GFPHLPTANPTG-PGERGPPGA 579
           G   AP                        GFP LP   P+G PG++GP GA
Sbjct: 941 GPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLP--GPSGEPGKQGPSGA 990



 Score = 32.0 bits (71), Expect = 1.9
 Identities = 16/29 (55%), Positives = 17/29 (58%), Gaps = 1/29 (3%)

Query: 3    PGGSGPGGCPRRPPALAGPLPPPPPPPPP 31
            PG  GP G PR     AGP+ PP PP PP
Sbjct: 1159 PGPIGPPG-PRGRTGDAGPVGPPGPPGPP 1186



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 32/102 (31%), Positives = 35/102 (34%), Gaps = 17/102 (16%)

Query: 486 PAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLG-------PGA 538
           P P       G+ G PG   A     P  PAG+     P  P       G       PGA
Sbjct: 481 PGPPGERGGPGSRGFPG---ADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGA 537

Query: 539 P-TSFEPRRPPPLRPGVTSAPGFPHLPTANPTGPGERGPPGA 579
              +  P  P P   G T  PG    P      PG  GPPGA
Sbjct: 538 KGLTGSPGSPGP--DGKTGPPG----PAGQDGRPGPPGPPGA 573



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 15/30 (50%), Positives = 17/30 (56%), Gaps = 1/30 (3%)

Query: 2   PPGGSGPGGCPRRPPALAGPLPPPPPPPPP 31
           P G  GP G P  P A +GP+ P  PP PP
Sbjct: 198 PQGFQGPPGEPGEPGA-SGPMGPRGPPGPP 226



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 31/98 (31%), Positives = 33/98 (33%), Gaps = 21/98 (21%)

Query: 483 PRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSF 542
           P +P  R      GA G PG    P         G   HR            GP  P   
Sbjct: 238 PGRPGERGPPGPQGARGLPGTAGLP---------GMKGHRGFSGLDGAKGDAGPAGP--- 285

Query: 543 EPRRPPPLRPGVTSAPGFPHLPTANPTG-PGERGPPGA 579
              +  P  PG   APG        P G PGERG PGA
Sbjct: 286 ---KGEPGSPGENGAPG-----QMGPRGLPGERGRPGA 315



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 29/88 (32%), Positives = 34/88 (38%), Gaps = 5/88 (5%)

Query: 496 GATGAPGVLFAPSAP-APNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEPRRPPPLR--P 552
           G+ GAPG+   P    A  LP  K +  D      +  P   G      P  PP     P
Sbjct: 719 GSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAP 778

Query: 553 GVT--SAPGFPHLPTANPTGPGERGPPG 578
           G    S P  P  PT     PG+RG PG
Sbjct: 779 GDKGESGPSGPAGPTGARGAPGDRGEPG 806



 Score = 29.6 bits (65), Expect = 9.4
 Identities = 30/94 (31%), Positives = 34/94 (36%), Gaps = 21/94 (22%)

Query: 486 PAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEPR 545
           P P       G+ GA G   AP  P P   AG+                  G P     R
Sbjct: 925 PGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRG--------------VVGLPGQRGER 970

Query: 546 RPPPLRPGVTSAPGFPHLPTANPTG-PGERGPPG 578
             P L PG +  PG        P+G  GERGPPG
Sbjct: 971 GFPGL-PGPSGEPG-----KQGPSGASGERGPPG 998


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 36/109 (33%), Positives = 40/109 (36%), Gaps = 6/109 (5%)

Query: 482  SPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPTS 541
            +P KP PR      G  G  G       P P    G      P  P  E  P GP  PT 
Sbjct: 902  TPGKPGPRGQRGPTGPRGERGPRGITGKPGPK---GNSGGDGPAGPPGERGPNGPQGPTG 958

Query: 542  FEPRRPPPLRPGVTSAPGFPHLPTANPTG-PGERGPPGAVEVIRESSST 589
            F   + PP  PG    PG P       TG  G+ GPPG   V+     T
Sbjct: 959  FPGPKGPPGPPGKDGLPGHP--GQRGETGFQGKTGPPGPPGVVGPQGPT 1005



 Score = 39.3 bits (90), Expect = 0.012
 Identities = 34/102 (33%), Positives = 39/102 (38%), Gaps = 7/102 (6%)

Query: 483 PRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLG----PGA 538
           P +  P+ +   DG  G PG       P P+ P G            E  P G    PG 
Sbjct: 621 PGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGP 680

Query: 539 PTSFEPRRP--PPLRPGVTSAPGFPHLPTANPTGPGERGPPG 578
                P+ P  PP  PGVT   G P  P  N    GE GPPG
Sbjct: 681 RGLLGPKGPPGPPGPPGVTGMDGQPG-PKGNVGPQGEPGPPG 721



 Score = 36.6 bits (83), Expect = 0.077
 Identities = 36/112 (32%), Positives = 43/112 (38%), Gaps = 12/112 (10%)

Query: 485 KPAPRPNLRTDGATGAPGVLFAPSA---PAPNLPAGKMNHRDPL-QPLLENPPLGPGAPT 540
           +P P+ N+   G  G PG    P A   P P    G    + PL +P L   P G   P 
Sbjct: 704 QPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMP-GADGPP 762

Query: 541 SFEPRRPPPLRPGVTSAPGFPHLPTANPTG-PGERGPPGAVEVIRESSSTTG 591
               +  PP   G    PG        P G PG RG  GA + IR    T G
Sbjct: 763 GHPGKEGPPGEKGGQGPPG-----PQGPIGYPGPRGVKGA-DGIRGLKGTKG 808



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 46/195 (23%), Positives = 66/195 (33%), Gaps = 34/195 (17%)

Query: 414 QDTLPPPAARRPPSGGPCQAERDDSDCEEPIEASGFASGEVFDSSLPPTDDEDFYTTFPL 473
           Q T P   A  P S          +    P E +    GE  + ++   D E++Y  +  
Sbjct: 366 QPTDPGAGAEIPTS--TADTSNSSNPAPPPGEGADDLEGEFTEETIRNLD-ENYYDPYYD 422

Query: 474 VTDRTTLLSPRKPAPRPNLRTD--------GATGAPGVL----FAPSAPAPNLPAGKMNH 521
            T   + + P  PA +  +           G  G P ++         P P  PAG    
Sbjct: 423 PTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAG---- 478

Query: 522 RDPLQPLLENPP--LGPGAPTSFEPRRPPPLRPGVTSAPGFPHLPTA------NPTGPGE 573
                  L  PP  +GP         R PP RPG+  A G P  P           G G+
Sbjct: 479 -------LPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGD 531

Query: 574 RGPPGAVEVIRESSS 588
            G  G +   +ES +
Sbjct: 532 AGSKGPMVSAQESQA 546



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 37/103 (35%), Positives = 40/103 (38%), Gaps = 26/103 (25%)

Query: 496  GATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPL-------------LENPP--LGPGAPT 540
            G TG+PG       P P+ P GK     P  P              LE PP   GP  P 
Sbjct: 1372 GQTGSPG---PTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQ 1428

Query: 541  SFEPRRPPP--LR--PGVTSAPGFPHLPTANPTG-PGERGPPG 578
               P +P P  LR  PG     G P  P   P G PG  GPPG
Sbjct: 1429 G-APGKPGPDGLRGIPGPVGEQGLPGSP--GPDGPPGPMGPPG 1468



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 29/96 (30%), Positives = 36/96 (37%), Gaps = 25/96 (26%)

Query: 486  PAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEPR 545
            P P+     DG  G+PG +  P  P P           P +P       GP         
Sbjct: 1323 PGPKGPPGDDGPKGSPGPVGFPGDPGP-----------PGEP-------GPAGQDGPPGD 1364

Query: 546  RPPPLRPGVTSAPGFPHLPTANP---TGPGERGPPG 578
            +     PG T +PG    PT  P     PG+RGPPG
Sbjct: 1365 KGDDGEPGQTGSPG----PTGEPGPSGPPGKRGPPG 1396



 Score = 33.9 bits (76), Expect = 0.50
 Identities = 26/83 (31%), Positives = 31/83 (37%), Gaps = 7/83 (8%)

Query: 496  GATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEPRRPPPLRPGVT 555
            G  G PG+   P    P  P G+   +    P     P GP  P   +    P   PG  
Sbjct: 1288 GEAGEPGL---PGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDD---GPKGSPGPV 1341

Query: 556  SAPGFPHLPTANPTGPGERGPPG 578
              PG P  P   P   G+ GPPG
Sbjct: 1342 GFPGDPG-PPGEPGPAGQDGPPG 1363



 Score = 33.9 bits (76), Expect = 0.50
 Identities = 33/114 (28%), Positives = 41/114 (35%), Gaps = 20/114 (17%)

Query: 483  PRKPAPRPNLRTD----GATGAPGV--LFAPSA----------PAPNLPAGKMNHRDPLQ 526
            P  P   P L+ D    G  G PG+  L  P            P P   +G    +    
Sbjct: 1463 PMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITG 1522

Query: 527  PLLENPPLGPGAPTSFEPRRPPPLRPGVTSAPGFPHLPTANPTGPGERGPPGAV 580
            P   + P+GP  P    P  P P     +S P  P     +P  PG  GPPG V
Sbjct: 1523 P---SGPIGPPGPPGL-PGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEV 1572



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 38/123 (30%), Positives = 41/123 (33%), Gaps = 26/123 (21%)

Query: 483  PRKPAPRPNLRTDGATGAPGV--LFAPSAPAPNL-PAGKMNHRDPLQPLLEN--PPLGPG 537
            P  P  R      G TG PG   +  P  P     P G+  H  P  P  E   P L   
Sbjct: 975  PGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGK 1034

Query: 538  APTSFEPRR--------PPPLR--------PGVTSAPGF-----PHLPTANPTGPGERGP 576
              T  +P          PP LR        PG   A G      P  P      PGERGP
Sbjct: 1035 EGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGP 1094

Query: 577  PGA 579
             GA
Sbjct: 1095 AGA 1097



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 29/99 (29%), Positives = 35/99 (35%), Gaps = 18/99 (18%)

Query: 483  PRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSF 542
            P  P P  +    G  GA G +  P  P P  P G    +              GAP   
Sbjct: 1080 PGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEK--------------GAPGEK 1125

Query: 543  EPRRPPPLRPGVTSAPGFPHLPTANPTG-PGERGPPGAV 580
             P+ P   R G+    G P    A P G PGE G  G +
Sbjct: 1126 GPQGPAG-RDGLQGPVGLP--GPAGPVGPPGEDGDKGEI 1161



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 35/104 (33%), Positives = 42/104 (40%), Gaps = 18/104 (17%)

Query: 483  PRKPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENP-PLGPGAPTS 541
            P +P P+      G  G  G   AP    P  PAG    RD LQ  +  P P GP  P  
Sbjct: 1104 PGRPGPQ------GPPGPAGEKGAPGEKGPQGPAG----RDGLQGPVGLPGPAGPVGPPG 1153

Query: 542  FEPRRPPPLRPGVTSAPG-----FPHLPTANPTGP-GERGPPGA 579
             +  +     PG   + G      P  PT  P GP G+ GP GA
Sbjct: 1154 EDGDKGEIGEPGQKGSKGDKGEQGPPGPT-GPQGPIGQPGPSGA 1196



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 37/134 (27%), Positives = 41/134 (30%), Gaps = 48/134 (35%)

Query: 485  KPAPRPNLRTDGATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGAP----- 539
            KP P+ N   DG  G PG         PN P G      P  P    PP   G P     
Sbjct: 929  KPGPKGNSGGDGPAGPPG------ERGPNGPQGPTGFPGPKGP--PGPPGKDGLPGHPGQ 980

Query: 540  ---TSFEPRRPPPLRPGVTS------------------------APGFPHLP-------T 565
               T F+ +  PP  PGV                            G P L         
Sbjct: 981  RGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGD 1040

Query: 566  ANPTG-PGERGPPG 578
              P G PG+ GPPG
Sbjct: 1041 PGPAGLPGKDGPPG 1054



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 14/27 (51%), Positives = 15/27 (55%), Gaps = 1/27 (3%)

Query: 2   PPGGSGPGGCPRRPPALAGPLPPPPPP 28
           PPG  GP G P+ P    GP  PP PP
Sbjct: 944 PPGERGPNG-PQGPTGFPGPKGPPGPP 969



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 26/93 (27%), Positives = 31/93 (33%), Gaps = 11/93 (11%)

Query: 496  GATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEPRRPPPLRPGVT 555
            G  G PG   A   P P    G    +    P     P GP  P   +    PP   G T
Sbjct: 1186 GPIGQPGPSGADGEPGPRGQQGLFGQKGDEGP--RGFP-GPPGPVGLQGLPGPPGEKGET 1242

Query: 556  S--------APGFPHLPTANPTGPGERGPPGAV 580
                      P  P  P+  P   G +GPPG +
Sbjct: 1243 GDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGI 1275



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 17/35 (48%), Positives = 18/35 (51%), Gaps = 4/35 (11%)

Query: 2    PPGGSGPGGCP--RRPPALAGP--LPPPPPPPPPP 32
            PPG  GP G P  R P   AGP  +P  P P  PP
Sbjct: 1079 PPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPP 1113



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 18/41 (43%), Positives = 21/41 (51%), Gaps = 3/41 (7%)

Query: 2    PPGGSGPGGC--PRRPPALAG-PLPPPPPPPPPPLLPLLPL 39
            PPG  G  G   P  P   AG P PP PP PP  ++  LP+
Sbjct: 1538 PPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLPI 1578



 Score = 29.6 bits (65), Expect = 9.4
 Identities = 15/30 (50%), Positives = 15/30 (50%), Gaps = 2/30 (6%)

Query: 4   GGSGPGGCPRRPP--ALAGPLPPPPPPPPP 31
           G  GP G P  P    L GP  PP PP PP
Sbjct: 667 GEVGPRGLPGEPGPRGLLGPKGPPGPPGPP 696


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.135    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,941,136
Number of Sequences: 37866
Number of extensions: 2336300
Number of successful extensions: 39435
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 627
Number of HSP's successfully gapped in prelim test: 778
Number of HSP's that attempted gapping in prelim test: 17300
Number of HSP's gapped (non-prelim): 16064
length of query: 666
length of database: 18,247,518
effective HSP length: 109
effective length of query: 557
effective length of database: 14,120,124
effective search space: 7864909068
effective search space used: 7864909068
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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