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Search of human proteins with 210147558
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|210147558 hypothetical protein LOC202051 [Homo sapiens]
(205 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|210147558 hypothetical protein LOC202051 [Homo sapiens] 395 e-110
gi|21735548 centrosomal protein 2 [Homo sapiens] 52 5e-07
gi|217416392 pleckstrin homology domain containing, family H (wi... 49 3e-06
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 49 3e-06
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 48 5e-06
gi|109134347 NY-REN-58 antigen [Homo sapiens] 47 9e-06
gi|109134355 NY-REN-58 antigen [Homo sapiens] 47 9e-06
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 47 1e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 47 1e-05
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 46 2e-05
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 46 2e-05
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 46 2e-05
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 46 2e-05
gi|221219020 NYD-SP11 protein [Homo sapiens] 46 3e-05
gi|38569484 kinesin family member 21A [Homo sapiens] 46 3e-05
gi|90819229 cutaneous T-cell lymphoma-associated antigen 1 isofo... 45 3e-05
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 45 3e-05
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 45 4e-05
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 45 4e-05
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 45 4e-05
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 45 4e-05
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 45 4e-05
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 45 4e-05
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 45 4e-05
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 45 4e-05
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 45 4e-05
gi|124249396 coiled-coil domain containing 30 [Homo sapiens] 44 7e-05
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 44 1e-04
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 44 1e-04
gi|4507693 tuberous sclerosis 1 protein isoform 1 [Homo sapiens] 44 1e-04
>gi|210147558 hypothetical protein LOC202051 [Homo sapiens]
Length = 205
Score = 395 bits (1014), Expect = e-110
Identities = 205/205 (100%), Positives = 205/205 (100%)
Query: 1 MATPLGWSKAGSGSVCLALDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKL 60
MATPLGWSKAGSGSVCLALDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKL
Sbjct: 1 MATPLGWSKAGSGSVCLALDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKL 60
Query: 61 VEEKAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKK 120
VEEKAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKK
Sbjct: 61 VEEKAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKK 120
Query: 121 DQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMA 180
DQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMA
Sbjct: 121 DQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMA 180
Query: 181 QVLDQKHKKASGTRQARSHQHPREK 205
QVLDQKHKKASGTRQARSHQHPREK
Sbjct: 181 QVLDQKHKKASGTRQARSHQHPREK 205
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 51.6 bits (122), Expect = 5e-07
Identities = 43/172 (25%), Positives = 86/172 (50%), Gaps = 15/172 (8%)
Query: 30 EELIHQLRNVMVLQDENFVS-KEEFQAVEK----KLVEEKAAHAKTKVL---LAKEEEKL 81
EE + R+ + L++E S +E QA+++ K+ + KA +L LA+ EE++
Sbjct: 1378 EEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEV 1437
Query: 82 QFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQL--ITKCNEIESH----II 135
+ G+++ L KQ E +K A E +K + + +++Q+ + KC + H +
Sbjct: 1438 ETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQ 1497
Query: 136 KQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQ-ESYMAQVLDQK 186
++E L + +I+EL++ Q+ + + + + + Q ES QV D K
Sbjct: 1498 EREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLK 1549
Score = 36.6 bits (83), Expect = 0.015
Identities = 39/200 (19%), Positives = 93/200 (46%), Gaps = 24/200 (12%)
Query: 21 QLRDVIESQEELIHQLRNVMV-LQDENFVSKEEFQAVEKKLVE-----------EKAAHA 68
Q++ V +++E + ++R + + L E +++E A ++L + +KAAH
Sbjct: 793 QIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHE 852
Query: 69 K-TKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKC 127
K L K E++ + E+ + LE+EK+ E L ++++ +++++ T+
Sbjct: 853 KEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQA 912
Query: 128 NEIESHIIKQEDILNGKENEIKELQQVISQQKQI------FRNHMSDFRIQKQQESYMAQ 181
ES + + + L ++ + L+ ++ QK++ D ++QK +E
Sbjct: 913 ---ESALCQMQ--LETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTG 967
Query: 182 VLDQKHKKASGTRQARSHQH 201
+L + ++A + + QH
Sbjct: 968 ILQTQLQEAQRELKEAARQH 987
Score = 36.2 bits (82), Expect = 0.020
Identities = 36/187 (19%), Positives = 80/187 (42%), Gaps = 17/187 (9%)
Query: 23 RDVIESQEELIHQLRNVMVLQDENF----VSKEEFQAVEKKLVEEKAAHAKTKVLLAKEE 78
+D+ +EL+ Q + VL+D+ + +E+ + ++ L E + L+ +
Sbjct: 1651 QDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLM---Q 1707
Query: 79 EKLQFALGEVEVLSKQLEKEKLAF---EKALSSVKSKVLQESSKKDQLITKCNEIESHII 135
E+ + G + LE KL EK + + + + KDQL + + +
Sbjct: 1708 ERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVG 1767
Query: 136 KQEDILNGKENEIKELQQVISQ-------QKQIFRNHMSDFRIQKQQESYMAQVLDQKHK 188
+ +L+ +E EI LQQ + + ++Q ++ + + + Q + L Q+ +
Sbjct: 1768 ETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQ 1827
Query: 189 KASGTRQ 195
+A G +
Sbjct: 1828 QAQGQEE 1834
Score = 34.3 bits (77), Expect = 0.076
Identities = 35/184 (19%), Positives = 72/184 (39%), Gaps = 12/184 (6%)
Query: 22 LRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKL 81
LRD+ E +EE+ +L Q+ E+ K+ E A + K L +E+ L
Sbjct: 682 LRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAAL 741
Query: 82 QFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDIL 141
+ L VE + L ++ A ++S + + + + ++E I
Sbjct: 742 EVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQI------- 794
Query: 142 NGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQE-SYMAQVLDQKHKKASGTRQARSHQ 200
+ + ++VI + + + + R Q +QE A+ L Q ++ + +
Sbjct: 795 ----QTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAA 850
Query: 201 HPRE 204
H +E
Sbjct: 851 HEKE 854
Score = 33.5 bits (75), Expect = 0.13
Identities = 33/161 (20%), Positives = 73/161 (45%), Gaps = 12/161 (7%)
Query: 29 QEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEV 88
QE L + + ++E + + Q +EK+ +KAA + L K +++ ++
Sbjct: 1420 QENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQI 1479
Query: 89 EVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENEI 148
+ +LEK + E +V+ + + + +++Q+ E+E Q ++L + E+
Sbjct: 1480 Q----ELEKCRSVLEHLPMAVQEREQKLTVQREQI----RELEKDRETQRNVLEHQLLEL 1531
Query: 149 KELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
++ Q+I Q R + D + Q +A L++ H K
Sbjct: 1532 EKKDQMIESQ----RGQVQDLKKQLVTLECLALELEENHHK 1568
Score = 32.7 bits (73), Expect = 0.22
Identities = 34/167 (20%), Positives = 74/167 (44%), Gaps = 8/167 (4%)
Query: 17 LALDQLRDVIESQEELIHQL-------RNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAK 69
+A+ + + Q E I +L RNV+ Q K++ ++ V++
Sbjct: 1494 MAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLV 1553
Query: 70 TKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNE 129
T LA E E+ + + L K+LE ++ AL+ + + + S + ++ ++
Sbjct: 1554 TLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHD 1613
Query: 130 IESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQE 176
+ESH L ++ E+K ++ I ++ Q + H++ ++ QE
Sbjct: 1614 LESHSTVLARELQERDQEVKSQREQI-EELQRQKEHLTQDLERRDQE 1659
Score = 31.6 bits (70), Expect = 0.49
Identities = 37/203 (18%), Positives = 90/203 (44%), Gaps = 28/203 (13%)
Query: 26 IESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFAL 85
+E+++E + L ++ Q E + ++ + + + + +K +T +L + ++ Q L
Sbjct: 921 LETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQREL 980
Query: 86 GE-----------VEVLSKQLEKEKLAFEKALSSVKSKVL----------QESSKKDQLI 124
E ++ S L ++K+ +K + +KS+++ QE +K +
Sbjct: 981 KEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRET 1040
Query: 125 TKCNEIESHIIKQEDILN----GKENEIKELQQVIS---QQKQIFRNHMSDFRIQKQQES 177
+ N I+ + +++ L KE + LQ+ S Q+ R M + + ++++ S
Sbjct: 1041 QEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELS 1100
Query: 178 YMAQVLDQKHKKASGTRQARSHQ 200
++L Q+ K+ A+ Q
Sbjct: 1101 AQMELLRQEVKEKEADFLAQEAQ 1123
Score = 31.2 bits (69), Expect = 0.64
Identities = 35/194 (18%), Positives = 83/194 (42%), Gaps = 13/194 (6%)
Query: 9 KAGSGSVCLALDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHA 68
K + V L +Q++++ + + L H V + + V +E+ + +EK ++
Sbjct: 1466 KKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLE 1525
Query: 69 KTKVLLAKEEEKLQFALGEVEVLSKQL-EKEKLAFEKALSSVKSKVLQESSKK------- 120
+ L K+++ ++ G+V+ L KQL E LA E + K + Q+ K+
Sbjct: 1526 HQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRET 1585
Query: 121 -----DQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQ 175
L E + Q ++ E+ L + + ++ Q ++ ++Q
Sbjct: 1586 QRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQ 1645
Query: 176 ESYMAQVLDQKHKK 189
+ ++ Q L+++ ++
Sbjct: 1646 KEHLTQDLERRDQE 1659
>gi|217416392 pleckstrin homology domain containing, family H (with
MyTH4 domain) member 2 [Homo sapiens]
Length = 1493
Score = 48.9 bits (115), Expect = 3e-06
Identities = 29/112 (25%), Positives = 64/112 (57%), Gaps = 3/112 (2%)
Query: 50 KEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSV 109
KE A+E +L++ + +K + LLA++ ++L+ + + E +Q EK + +
Sbjct: 14 KERCVALESQLMKFRVQASKIRELLAEKMQQLERQVIDAE---RQAEKAFQQVQVMEDKL 70
Query: 110 KSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQI 161
K+ +Q S + +L KC ++ES I +++D++ E +++E +Q+ Q+ +I
Sbjct: 71 KAANIQTSESETRLYNKCQDLESLIQEKDDVIQNLELQLEEQKQIRIQEAKI 122
Score = 31.6 bits (70), Expect = 0.49
Identities = 34/165 (20%), Positives = 68/165 (41%), Gaps = 21/165 (12%)
Query: 21 QLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEK 80
+L + + E LI + +V+ + +++ + E K++EEKAA K V + E +
Sbjct: 83 RLYNKCQDLESLIQEKDDVIQNLELQLEEQKQIRIQEAKIIEEKAAKIKEWVTVKLNELE 142
Query: 81 L---------QFALGEVEVLSKQLEKE-----------KLAFEKALSSVKSKVLQESSKK 120
L Q E+ + +L++ KL+ + LSS+ ++
Sbjct: 143 LENQNLRLINQNQTEEIRTMQSKLQEVQGKKSSTVSTLKLSEGQRLSSLTFGCFLSRARS 202
Query: 121 DQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNH 165
+ K E+ K+ + GK+ E E+ + S Q+ N+
Sbjct: 203 PPQVVKSEEMSKISSKEPEFTEGKDMEEMEIPEK-SVDNQVLENN 246
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 48.9 bits (115), Expect = 3e-06
Identities = 34/152 (22%), Positives = 77/152 (50%), Gaps = 3/152 (1%)
Query: 23 RDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVE---EKAAHAKTKVLLAKEEE 79
++++E+Q+E+ R + ++ + KE+ A E LV+ E+ K K L E +
Sbjct: 503 KNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESALVKLHLEQQRIEKEKETLKAELQ 562
Query: 80 KLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQED 139
KL+ E + ++ E E+ + ++ + L++ + DQ+I++ + + S ++++ D
Sbjct: 563 KLRQQALETKHFIEKQEAEERKLLRIIAEADGERLRQKKELDQVISERDILGSQLVRRND 622
Query: 140 ILNGKENEIKELQQVISQQKQIFRNHMSDFRI 171
L +IK Q V+++ + + + D RI
Sbjct: 623 ELALLYEKIKIQQSVLNKGESQYNQRLEDMRI 654
Score = 43.9 bits (102), Expect = 1e-04
Identities = 31/144 (21%), Positives = 66/144 (45%), Gaps = 1/144 (0%)
Query: 58 KKLVEEKAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQES 117
+ L+ K K + L E KL+ +L + ++ E+ K E A+S + ++ Q
Sbjct: 149 RDLLRFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQ 208
Query: 118 SKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQES 177
++ + K ++E + + + ++ ++ EIK LQQ + + K+ + + QK
Sbjct: 209 NEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNE 268
Query: 178 YMAQVLDQKHKKASGTRQARSHQH 201
A+ L+Q + + Q + QH
Sbjct: 269 RAAKELEQ-FQMRNAKLQQENEQH 291
Score = 39.7 bits (91), Expect = 0.002
Identities = 39/200 (19%), Positives = 101/200 (50%), Gaps = 19/200 (9%)
Query: 14 SVCLALDQLRDVIESQEELIHQLRNVM--VLQDENFVSKE--EFQAVEKKLVEEKAAHAK 69
S+ +Q ++ S+EE H + + Q +N S+E + + +EK+L + +A
Sbjct: 175 SLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDS 234
Query: 70 TKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALS-----SVKSKVLQESSKKDQLI 124
+ + ++ +Q + E++ L +QL+++K+ E+A +++ LQ+ +++ L+
Sbjct: 235 RQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQHSLV 294
Query: 125 TKCNEIESHIIKQEDILNGKENEIKELQQVISQ----QKQIFR--NHMSDFR--IQKQQE 176
C ++ ++ L KE E+ +++ I + ++QI + +H D + +++ +E
Sbjct: 295 --CEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKE 352
Query: 177 SYMAQVLDQKHKKASGTRQA 196
+ Q++ + + + +QA
Sbjct: 353 TLKNQIVGLEREVEASKKQA 372
Score = 38.9 bits (89), Expect = 0.003
Identities = 44/205 (21%), Positives = 90/205 (43%), Gaps = 43/205 (20%)
Query: 27 ESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHA------------KTKVLL 74
E ++L QL+ +L + E+FQ KL +E H+ K L
Sbjct: 251 EELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALELK 310
Query: 75 AKEEE--KLQFALGEVEVLSKQLEK-------EKLAFEKALSSVKSKVL-----QESSKK 120
AKEEE +++ +G++ + +Q+ K +K E+ ++K++++ E+SKK
Sbjct: 311 AKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKK 370
Query: 121 ---------DQLITKCNEIESHII-------KQEDILNGKENEIKELQQVISQQK-QIFR 163
D+L+ + + + +++ KQ D++ E + L+ I K + +
Sbjct: 371 QAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQK 430
Query: 164 NHMSDFRIQKQQESYMAQVLDQKHK 188
F ++K+++ Y+ Q D K
Sbjct: 431 QRKIIFHLEKERDRYINQASDLTQK 455
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 48.1 bits (113), Expect = 5e-06
Identities = 41/180 (22%), Positives = 84/180 (46%), Gaps = 25/180 (13%)
Query: 26 IESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFAL 85
I QEE I + M Q+E +E+ + EK+ +E+ + ++EEK++
Sbjct: 425 IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE---------MWRQEEKIR--- 472
Query: 86 GEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKE 145
E E + +Q KEK+ ++ + + KV ++ K K E E + +QE+ + +E
Sbjct: 473 -EQEEIWRQ--KEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQE 529
Query: 146 NEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKASGTRQARSHQHPREK 205
+I+E ++ I +Q++ + ++QE M + ++ ++ RQ + EK
Sbjct: 530 EKIREQEEKIREQEE----------MMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEK 579
Score = 46.2 bits (108), Expect = 2e-05
Identities = 37/188 (19%), Positives = 90/188 (47%), Gaps = 15/188 (7%)
Query: 19 LDQLRDVIESQEELIHQLRNVMVLQDENFVSKEE-FQAVEKKLVEEKAAHAKTKVLLAKE 77
+ + + I QEE I + M Q+E KEE + E+ + E++ + + ++ ++
Sbjct: 316 IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEK 375
Query: 78 EEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQ 137
EEK++ E+ K E+EK+ ++ + K+ ++ +++Q E+ + +Q
Sbjct: 376 EEKIR------ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ--------EAKMWRQ 421
Query: 138 EDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKASGTRQAR 197
E+ + +E +I+E ++ + +Q++ +K+QE ++K ++ + +
Sbjct: 422 EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK 481
Query: 198 SHQHPREK 205
H +EK
Sbjct: 482 EKMHEQEK 489
Score = 44.3 bits (103), Expect = 7e-05
Identities = 37/162 (22%), Positives = 81/162 (50%), Gaps = 6/162 (3%)
Query: 29 QEELIHQLRNVMVLQDENFVSKEE-FQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGE 87
QEE +H + Q+E +EE + E+K+ E++ + + ++ ++EEK +GE
Sbjct: 500 QEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEK----MGE 555
Query: 88 VEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENE 147
E ++ EK + EK + + K+ ++ K + K E E I +QE+++ +E +
Sbjct: 556 QEEKMQEQEKMRRQEEK-IREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEK 614
Query: 148 IKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
+ E ++ + +Q++ + R Q+++ L Q+ +K
Sbjct: 615 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 656
Score = 41.6 bits (96), Expect = 5e-04
Identities = 36/194 (18%), Positives = 97/194 (50%), Gaps = 14/194 (7%)
Query: 23 RDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQ 82
++ I Q+E +H+ + +++ + +E+ E+K+ E++ + + + ++EEK++
Sbjct: 474 QEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIR 533
Query: 83 FALGEV----EVLSKQLEK-----EKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESH 133
++ E++ +Q EK EK+ ++ + + K+ ++ K + K E E
Sbjct: 534 EQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEK 593
Query: 134 IIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQ---VLDQKHKKA 190
I +QE+ + +E ++E ++ + +Q++ + + ++Q+Q+E Q + +Q+ +
Sbjct: 594 IWEQEEKIREQEEMMQEQEEKMWEQEE--KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 651
Query: 191 SGTRQARSHQHPRE 204
+ + HQ E
Sbjct: 652 QQEEKMQEHQEHLE 665
Score = 40.8 bits (94), Expect = 8e-04
Identities = 43/197 (21%), Positives = 88/197 (44%), Gaps = 22/197 (11%)
Query: 30 EELIHQLRNVMVLQDENFVSKEEFQAVEKKLVE--EKAAHAKTKVLLAKEEEKLQFALGE 87
EEL + + + N ++ EE + KL E + K+++ L +E K + +
Sbjct: 196 EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK 255
Query: 88 VEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCN---------------EIES 132
+ + +QL+ E K L SV +K LQ ++++L + N E E
Sbjct: 256 LLLPQQQLQAEADHLGKELQSVSAK-LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEE 314
Query: 133 HIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQK----QQESYMAQVLDQKHK 188
I +QE+ + +E +I+E ++ + +Q+++ R Q+ ++E M ++ + +
Sbjct: 315 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWE 374
Query: 189 KASGTRQARSHQHPREK 205
K R+ H +EK
Sbjct: 375 KEEKIRELEEKMHEQEK 391
Score = 36.6 bits (83), Expect = 0.015
Identities = 36/176 (20%), Positives = 85/176 (48%), Gaps = 11/176 (6%)
Query: 20 DQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEE 79
+++ + + +EE Q + M Q+E +EE ++K+ E++ K + + ++EE
Sbjct: 444 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIR-KQEEKVWRQEE 502
Query: 80 KLQFALGEVEVLSKQLEK-----EKL-AFEKALSSVKSKVLQESSKKDQLITKCNEIESH 133
K+ + E + +Q EK EK+ E+ + + K+ ++ + K E E
Sbjct: 503 KMH---DQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEK 559
Query: 134 IIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
+ +QE + +E +I+E ++ I +QK+ R Q+++ +++ ++ +K
Sbjct: 560 MQEQEK-MRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEK 614
Score = 28.9 bits (63), Expect = 3.2
Identities = 22/116 (18%), Positives = 58/116 (50%), Gaps = 4/116 (3%)
Query: 19 LDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEE 78
+ + + ++ QE++ Q + +++ KE+ + E+K+ E++ + + ++ ++E
Sbjct: 553 MGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQE 612
Query: 79 EKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHI 134
EK+ + E + +Q EK + EK + + K+ ++ + Q K E + H+
Sbjct: 613 EKM---WEQEEKMCEQEEKMQEQEEK-MRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664
>gi|109134347 NY-REN-58 antigen [Homo sapiens]
Length = 701
Score = 47.4 bits (111), Expect = 9e-06
Identities = 41/177 (23%), Positives = 84/177 (47%), Gaps = 17/177 (9%)
Query: 25 VIESQEELIHQLR--------NVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAK 76
++E ELI +++ ++VLQDE + +EK VE K +
Sbjct: 369 LVEKDRELIRKVQAAKEEGYQKLVVLQDEKLELENRLADLEKMKVEHDVWRQSEK---DQ 425
Query: 77 EEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKS---KVLQESSKKDQLITKCNEIESH 133
EEKL+ + E+ K+L+ +L ++ + ++++ + + S K Q+ + ++ S
Sbjct: 426 YEEKLRASQMAEEITRKELQSVRLKLQQQIVTIENAEKEKNENSDLKQQISSLQIQVTSL 485
Query: 134 IIKQEDILNGKENEIKELQQVISQQKQIFRN--HMSDFRIQKQQESYMAQVLDQKHK 188
+ D+LN + +KE+ + + Q+ + FR+ + +K E Q L++KHK
Sbjct: 486 AQSENDLLNSNQ-MLKEMVERLKQECRNFRSQAEKAQLEAEKTLEEKQIQWLEEKHK 541
Score = 29.6 bits (65), Expect = 1.9
Identities = 40/162 (24%), Positives = 74/162 (45%), Gaps = 24/162 (14%)
Query: 21 QLRDVIESQEELIH--QLRNVMV--LQDE--NFVSKEEFQAVE-KKLVEEKAAH-----A 68
Q+ + +S+ +L++ Q+ MV L+ E NF S+ E +E +K +EEK
Sbjct: 481 QVTSLAQSENDLLNSNQMLKEMVERLKQECRNFRSQAEKAQLEAEKTLEEKQIQWLEEKH 540
Query: 69 KTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCN 128
K + EEK A +++ + +K K E L ++ KV +KK++L T
Sbjct: 541 KLHERITDREEKYNQAKEKLQRAAIAQKKRKSLHENKLKRLQEKVEVLEAKKEELET--- 597
Query: 129 EIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFR 170
+ +LN + ++ ++ + K I R H ++FR
Sbjct: 598 --------ENQVLNRQNVPFEDYTRLQKRLKDIQRRH-NEFR 630
>gi|109134355 NY-REN-58 antigen [Homo sapiens]
Length = 701
Score = 47.4 bits (111), Expect = 9e-06
Identities = 41/177 (23%), Positives = 84/177 (47%), Gaps = 17/177 (9%)
Query: 25 VIESQEELIHQLR--------NVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAK 76
++E ELI +++ ++VLQDE + +EK VE K +
Sbjct: 369 LVEKDRELIRKVQAAKEEGYQKLVVLQDEKLELENRLADLEKMKVEHDVWRQSEK---DQ 425
Query: 77 EEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKS---KVLQESSKKDQLITKCNEIESH 133
EEKL+ + E+ K+L+ +L ++ + ++++ + + S K Q+ + ++ S
Sbjct: 426 YEEKLRASQMAEEITRKELQSVRLKLQQQIVTIENAEKEKNENSDLKQQISSLQIQVTSL 485
Query: 134 IIKQEDILNGKENEIKELQQVISQQKQIFRN--HMSDFRIQKQQESYMAQVLDQKHK 188
+ D+LN + +KE+ + + Q+ + FR+ + +K E Q L++KHK
Sbjct: 486 AQSENDLLNSNQ-MLKEMVERLKQECRNFRSQAEKAQLEAEKTLEEKQIQWLEEKHK 541
Score = 29.6 bits (65), Expect = 1.9
Identities = 40/162 (24%), Positives = 74/162 (45%), Gaps = 24/162 (14%)
Query: 21 QLRDVIESQEELIH--QLRNVMV--LQDE--NFVSKEEFQAVE-KKLVEEKAAH-----A 68
Q+ + +S+ +L++ Q+ MV L+ E NF S+ E +E +K +EEK
Sbjct: 481 QVTSLAQSENDLLNSNQMLKEMVERLKQECRNFRSQAEKAQLEAEKTLEEKQIQWLEEKH 540
Query: 69 KTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCN 128
K + EEK A +++ + +K K E L ++ KV +KK++L T
Sbjct: 541 KLHERITDREEKYNQAKEKLQRAAIAQKKRKSLHENKLKRLQEKVEVLEAKKEELET--- 597
Query: 129 EIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFR 170
+ +LN + ++ ++ + K I R H ++FR
Sbjct: 598 --------ENQVLNRQNVPFEDYTRLQKRLKDIQRRH-NEFR 630
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 47.0 bits (110), Expect = 1e-05
Identities = 43/183 (23%), Positives = 89/183 (48%), Gaps = 18/183 (9%)
Query: 26 IESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEE--KAAHAKTKVLLAKEEEKLQF 83
+ES + L+ + + M + EN E +A++ ++ EE K + + + KEE L
Sbjct: 805 LESLDRLLTESKGEM--KKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHL 862
Query: 84 AL--GEVEVLSKQLEK---EKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQE 138
G E KQL+K E +K L +K+ LQE+S+++ ++ + + +++QE
Sbjct: 863 NQLEGNKEKFEKQLKKKSEEVYCLQKELK-IKNHSLQETSEQNVILQHTLQQQQQMLQQE 921
Query: 139 DILNGK--------ENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKA 190
I NG+ E ++ +L+Q + +Q++ + + + ++ A + QK +
Sbjct: 922 TIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIEL 981
Query: 191 SGT 193
+GT
Sbjct: 982 TGT 984
Score = 38.9 bits (89), Expect = 0.003
Identities = 40/143 (27%), Positives = 64/143 (44%), Gaps = 20/143 (13%)
Query: 29 QEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEV 88
QEEL+ + N L+ E + +EK+L E+ A++ A+ E++L ++
Sbjct: 675 QEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKI 734
Query: 89 EVLSKQL----EKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGK 144
L + EK LAFEKA K+ E K E+E I + E L K
Sbjct: 735 RSLETNINTEHEKICLAFEKA-----KKIHLEQHK---------EMEKQIERLEAQLEKK 780
Query: 145 ENEIKELQQVIS--QQKQIFRNH 165
+ + KE ++ +S QQ I + H
Sbjct: 781 DQQFKEQEKTMSMLQQDIICKQH 803
Score = 35.0 bits (79), Expect = 0.045
Identities = 42/186 (22%), Positives = 79/186 (42%), Gaps = 8/186 (4%)
Query: 18 ALDQLRDVIESQE-ELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAK 76
A+ +L + S E EL L+ VL+ E + E ++ ++L E + K ++ L +
Sbjct: 1040 AVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEE 1099
Query: 77 EEEKLQFALGEVEVLSKQLEKEK---LAFEKALSSVKSKVLQESSKKDQLITKCNE---- 129
+ ++ E+ ++E +K L ++AL ++ Q +++ L E
Sbjct: 1100 KYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGE 1159
Query: 130 IESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
+E IIK E L E E+KE + I +N R ++ Q + Q K+
Sbjct: 1160 MEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKE 1219
Query: 190 ASGTRQ 195
T+Q
Sbjct: 1220 IERTQQ 1225
Score = 32.7 bits (73), Expect = 0.22
Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 8/76 (10%)
Query: 54 QAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKV 113
+A +++ + HAK K+ ++ V+ L++QLEK KL E+A +V S +
Sbjct: 1341 EAYHMEMISHQENHAKWKISADSQK-------SSVQQLNEQLEKAKLELEEAQDTV-SNL 1392
Query: 114 LQESSKKDQLITKCNE 129
Q+ ++++I NE
Sbjct: 1393 HQQVQDRNEVIEAANE 1408
Score = 29.3 bits (64), Expect = 2.4
Identities = 19/106 (17%), Positives = 48/106 (45%), Gaps = 8/106 (7%)
Query: 91 LSKQLEKEKLAFEKALSSVKSKVLQ-ESSKKDQLITKCNEIESHIIKQEDILNGKENE-- 147
++KQ EKE+ + +++K++Q E+ D + + + QE++L N
Sbjct: 628 MNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSK 687
Query: 148 -----IKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHK 188
K+ Q+++ +KQ+ ++ I + +++++ K
Sbjct: 688 LESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEK 733
Score = 27.7 bits (60), Expect = 7.1
Identities = 31/121 (25%), Positives = 58/121 (47%), Gaps = 14/121 (11%)
Query: 42 LQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLA 101
L+D +SKE+ A L EE A +KV A E ++Q E++ LS ++E K A
Sbjct: 1290 LEDMKQLSKEK-DAHGNHLAEELGA---SKVREAHLEARMQ---AEIKKLSAEVESLKEA 1342
Query: 102 FEKALSS-----VKSKVLQESSKK--DQLITKCNEIESHIIKQEDILNGKENEIKELQQV 154
+ + S K K+ +S K QL + + + + + +D ++ ++++ +V
Sbjct: 1343 YHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEV 1402
Query: 155 I 155
I
Sbjct: 1403 I 1403
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 46.6 bits (109), Expect = 1e-05
Identities = 34/157 (21%), Positives = 76/157 (48%), Gaps = 6/157 (3%)
Query: 19 LDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEE 78
+ + + I+ QEE I + M Q+E KEE +++++ EK + E+
Sbjct: 297 IQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 356
Query: 79 EKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQE 138
EK++ E K+ E+EK+ ++ ++K+ ++ K + K E E + +QE
Sbjct: 357 EKIR------EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQE 410
Query: 139 DILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQ 175
+ + +E ++ E ++ + +Q++ R R Q+++
Sbjct: 411 EKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKK 447
Score = 46.2 bits (108), Expect = 2e-05
Identities = 35/178 (19%), Positives = 83/178 (46%), Gaps = 10/178 (5%)
Query: 26 IESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFAL 85
I QEE I + +M Q+E +EE K+ E++ + + + ++EEK++
Sbjct: 392 IREQEEKIREQEEMMQEQEEKMGEQEE------KMWEQEEEMQEQEEKMRRQEEKIR--- 442
Query: 86 GEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKE 145
E E ++ E++ E+ + + K+ ++ K + K E E + +QE+ + +E
Sbjct: 443 -EQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQE 501
Query: 146 NEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKASGTRQARSHQHPR 203
+I+E ++ I +Q+++ + Q+++ + + ++ +K + Q R
Sbjct: 502 KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVR 559
Score = 40.8 bits (94), Expect = 8e-04
Identities = 43/171 (25%), Positives = 77/171 (45%), Gaps = 16/171 (9%)
Query: 51 EEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGE-------VEVLSKQLEKEKLAFE 103
+E A+ +L + K AK +EKLQ E V+ L ++LE+ KL
Sbjct: 188 KERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLP 247
Query: 104 ----KALSSVKSKVLQESSKKDQLITKCNEIESHI-IKQEDILNGKENEIKELQQVISQQ 158
+A + K LQ S K Q + NE+ + + +QE+ + +E +I+E ++ I +Q
Sbjct: 248 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQ 307
Query: 159 KQIFRNHMSDFRIQK----QQESYMAQVLDQKHKKASGTRQARSHQHPREK 205
++ R R Q+ ++E M + + +K R+ H +EK
Sbjct: 308 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 358
Score = 40.4 bits (93), Expect = 0.001
Identities = 28/148 (18%), Positives = 73/148 (49%), Gaps = 5/148 (3%)
Query: 19 LDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEF-QAVEKKLVEEKAAHAKTKVLLAKE 77
+ + + + QEE I + + Q+E +EE Q E+K+ E++ + + + ++
Sbjct: 427 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQ 486
Query: 78 EEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQ 137
EEK++ ++ K++ ++ E+ + + + ++ K + K E E + +Q
Sbjct: 487 EEKMRRQEEKIREQEKKIREQ----EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 542
Query: 138 EDILNGKENEIKELQQVISQQKQIFRNH 165
E+ + +E +++E + + QQ++ + H
Sbjct: 543 EEKMRRQEEKMREQEVRLRQQEEKMQEH 570
Score = 35.8 bits (81), Expect = 0.026
Identities = 22/163 (13%), Positives = 79/163 (48%)
Query: 27 ESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALG 86
+ +E++ Q + +++ +E+ + E+K+ ++ + + + ++EE +
Sbjct: 285 QQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 344
Query: 87 EVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKEN 146
++ L +++ +++ E+ + + ++E K+ + K E I +QE+ + +E
Sbjct: 345 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEE 404
Query: 147 EIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
++E ++ + +Q++ + + Q+++ + + ++ KK
Sbjct: 405 MMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKK 447
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 46.2 bits (108), Expect = 2e-05
Identities = 44/172 (25%), Positives = 80/172 (46%), Gaps = 17/172 (9%)
Query: 30 EELIHQLRNVMV--------LQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKL 81
EE++H++ + LQ E ++ +E++L EE+AA K ++ E K+
Sbjct: 921 EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKI 980
Query: 82 QFALGEVEVLSKQ---LEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQE 138
+ E+ V+ Q L KE+ E+ +S + + + +E K L N+ ES I + E
Sbjct: 981 KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE 1040
Query: 139 DILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKA 190
L +E +EL+++ K+ SDF +Q AQ+ + K + A
Sbjct: 1041 VRLKKEEKSRQELEKL----KRKLEGDASDF--HEQIADLQAQIAELKMQLA 1086
Score = 41.2 bits (95), Expect = 6e-04
Identities = 40/171 (23%), Positives = 77/171 (45%), Gaps = 8/171 (4%)
Query: 21 QLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEK 80
Q I+ +EE I QLR + + E+ +A ++ + K L + +
Sbjct: 1632 QADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQ 1691
Query: 81 LQFALGEVEVLSKQ--LEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQE 138
LQ L E KQ LEKE+LA E A S LQ+ +K +L + ++E + +++
Sbjct: 1692 LQEDLAAAERARKQADLEKEELAEELASSLSGRNALQD--EKRRLEARIAQLEEELEEEQ 1749
Query: 139 DILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
+ + +++ +QQ + N ++ R Q+ Q L++++K+
Sbjct: 1750 GNMEAMSDRVRK----ATQQAEQLSNELATERSTAQKNESARQQLERQNKE 1796
Score = 35.0 bits (79), Expect = 0.045
Identities = 30/196 (15%), Positives = 88/196 (44%), Gaps = 14/196 (7%)
Query: 20 DQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEE 79
+++ D+ + E + +N+ L++++ E + KK + + K K L +
Sbjct: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1065
Query: 80 KLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQED 139
+ +++ +L+ + E+ L + +++ E ++K+ + K E+E HI ++
Sbjct: 1066 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1125
Query: 140 ILNGK---ENEIKELQQVISQQKQIFRNHMSD----------FRIQKQQE-SYMAQVLDQ 185
L+ + N+ ++ ++ + ++ + + + D R +++QE + + + LD+
Sbjct: 1126 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1185
Query: 186 KHKKASGTRQARSHQH 201
+ + Q +H
Sbjct: 1186 ETRSHEAQVQEMRQKH 1201
Score = 34.7 bits (78), Expect = 0.058
Identities = 42/186 (22%), Positives = 86/186 (46%), Gaps = 20/186 (10%)
Query: 21 QLRDVIES----QEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAK 76
+L D ++S QE + + V VL+ EE ++ E ++ E + HA+ L +
Sbjct: 1154 ELEDTLDSTATQQELRAKREQEVTVLKK---ALDEETRSHEAQVQEMRQKHAQAVEELTE 1210
Query: 77 EEEKLQFALGEVEVLSKQLEKEK--LAFE-KALSSVKSKVLQESSKKD----QLITKCNE 129
+ E+ + A ++ + LEKE LA E + L K +V + K + +L +KC++
Sbjct: 1211 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1270
Query: 130 IESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
E + D ++ +NE++ + ++++ + ++ K S +Q+ D +
Sbjct: 1271 GERARAELNDKVHKLQNEVESVTGMLNEAEG------KAIKLAKDVASLSSQLQDTQELL 1324
Query: 190 ASGTRQ 195
TRQ
Sbjct: 1325 QEETRQ 1330
Score = 33.9 bits (76), Expect = 0.099
Identities = 42/200 (21%), Positives = 89/200 (44%), Gaps = 41/200 (20%)
Query: 22 LRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKL 81
L + +E++EEL + ++ + E+ VS ++ V K + E + K+K L + E++
Sbjct: 1492 LEEALEAKEEL-ERTNKMLKAEMEDLVSSKD--DVGKNVHELE----KSKRALETQMEEM 1544
Query: 82 QFALGEVEVLSKQLEKEKLAFEKALSSVK--------SKVLQESSKKDQLITKCNEIESH 133
+ L E+E + E KL E + ++K ++ Q K+ QL + +E E+
Sbjct: 1545 KTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETE 1604
Query: 134 I-------------------------IKQEDILNGKENEIKELQQVISQQKQIFRNHMSD 168
+ ++ + + G+E IK+L+++ +Q K F+ + D
Sbjct: 1605 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKD-FQRELED 1663
Query: 169 FRIQKQQESYMAQVLDQKHK 188
R + + A+ ++K K
Sbjct: 1664 ARASRDEIFATAKENEKKAK 1683
Score = 33.5 bits (75), Expect = 0.13
Identities = 31/134 (23%), Positives = 58/134 (43%), Gaps = 15/134 (11%)
Query: 50 KEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSV 109
+EE QA E +L + K + ++K + L E+E QL +EK ++ L +
Sbjct: 851 EEEMQAKEDELQKTK-----------ERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 899
Query: 110 KSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDF 169
+ + +L K E+E + + E L +E+ ++LQ +++ M D
Sbjct: 900 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ----AERKKMAQQMLDL 955
Query: 170 RIQKQQESYMAQVL 183
Q ++E Q L
Sbjct: 956 EEQLEEEEAARQKL 969
Score = 33.1 bits (74), Expect = 0.17
Identities = 40/189 (21%), Positives = 86/189 (45%), Gaps = 19/189 (10%)
Query: 27 ESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAH---AKTKVLLAKEEEKLQF 83
+S+++L V L++ ++E + + ++ E+ AA+ KTK L +E + L
Sbjct: 1375 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1434
Query: 84 ALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIK----QED 139
L L LEK++ F++ L+ K+ + + ++D+ + E E+ + E+
Sbjct: 1435 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1494
Query: 140 ILNGKE-----NEI--KELQQVISQQKQIFRN----HMSDFRIQKQQESYMAQVLDQKHK 188
L KE N++ E++ ++S + + +N S ++ Q E Q L++
Sbjct: 1495 ALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQ-LEELED 1553
Query: 189 KASGTRQAR 197
+ T A+
Sbjct: 1554 ELQATEDAK 1562
Score = 31.6 bits (70), Expect = 0.49
Identities = 42/209 (20%), Positives = 85/209 (40%), Gaps = 23/209 (11%)
Query: 18 ALDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEE---------KAAHA 68
A+ QLR + ++ +L + +DE F + +E + K L + A A
Sbjct: 1643 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1702
Query: 69 KTKVLLAKEE--EKLQFALG----------EVEVLSKQLEKEKLAFEKALSSVKSKVLQE 116
+ + L KEE E+L +L +E QLE+E + + ++ +V +
Sbjct: 1703 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762
Query: 117 SSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQE 176
+ + +QL + S K E E + KEL+ + + + ++ E
Sbjct: 1763 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKS--TIAALE 1820
Query: 177 SYMAQVLDQKHKKASGTRQARSHQHPREK 205
+ +AQ+ +Q ++A + A ++K
Sbjct: 1821 AKIAQLEEQVEQEAREKQAATKSLKQKDK 1849
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 46.2 bits (108), Expect = 2e-05
Identities = 44/172 (25%), Positives = 80/172 (46%), Gaps = 17/172 (9%)
Query: 30 EELIHQLRNVMV--------LQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKL 81
EE++H++ + LQ E ++ +E++L EE+AA K ++ E K+
Sbjct: 928 EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKI 987
Query: 82 QFALGEVEVLSKQ---LEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQE 138
+ E+ V+ Q L KE+ E+ +S + + + +E K L N+ ES I + E
Sbjct: 988 KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE 1047
Query: 139 DILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKA 190
L +E +EL+++ K+ SDF +Q AQ+ + K + A
Sbjct: 1048 VRLKKEEKSRQELEKL----KRKLEGDASDF--HEQIADLQAQIAELKMQLA 1093
Score = 41.2 bits (95), Expect = 6e-04
Identities = 40/171 (23%), Positives = 77/171 (45%), Gaps = 8/171 (4%)
Query: 21 QLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEK 80
Q I+ +EE I QLR + + E+ +A ++ + K L + +
Sbjct: 1639 QADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQ 1698
Query: 81 LQFALGEVEVLSKQ--LEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQE 138
LQ L E KQ LEKE+LA E A S LQ+ +K +L + ++E + +++
Sbjct: 1699 LQEDLAAAERARKQADLEKEELAEELASSLSGRNALQD--EKRRLEARIAQLEEELEEEQ 1756
Query: 139 DILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
+ + +++ +QQ + N ++ R Q+ Q L++++K+
Sbjct: 1757 GNMEAMSDRVRK----ATQQAEQLSNELATERSTAQKNESARQQLERQNKE 1803
Score = 35.0 bits (79), Expect = 0.045
Identities = 30/196 (15%), Positives = 88/196 (44%), Gaps = 14/196 (7%)
Query: 20 DQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEE 79
+++ D+ + E + +N+ L++++ E + KK + + K K L +
Sbjct: 1013 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1072
Query: 80 KLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQED 139
+ +++ +L+ + E+ L + +++ E ++K+ + K E+E HI ++
Sbjct: 1073 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1132
Query: 140 ILNGK---ENEIKELQQVISQQKQIFRNHMSD----------FRIQKQQE-SYMAQVLDQ 185
L+ + N+ ++ ++ + ++ + + + D R +++QE + + + LD+
Sbjct: 1133 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1192
Query: 186 KHKKASGTRQARSHQH 201
+ + Q +H
Sbjct: 1193 ETRSHEAQVQEMRQKH 1208
Score = 34.7 bits (78), Expect = 0.058
Identities = 42/186 (22%), Positives = 86/186 (46%), Gaps = 20/186 (10%)
Query: 21 QLRDVIES----QEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAK 76
+L D ++S QE + + V VL+ EE ++ E ++ E + HA+ L +
Sbjct: 1161 ELEDTLDSTATQQELRAKREQEVTVLKK---ALDEETRSHEAQVQEMRQKHAQAVEELTE 1217
Query: 77 EEEKLQFALGEVEVLSKQLEKEK--LAFE-KALSSVKSKVLQESSKKD----QLITKCNE 129
+ E+ + A ++ + LEKE LA E + L K +V + K + +L +KC++
Sbjct: 1218 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1277
Query: 130 IESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
E + D ++ +NE++ + ++++ + ++ K S +Q+ D +
Sbjct: 1278 GERARAELNDKVHKLQNEVESVTGMLNEAEG------KAIKLAKDVASLSSQLQDTQELL 1331
Query: 190 ASGTRQ 195
TRQ
Sbjct: 1332 QEETRQ 1337
Score = 33.9 bits (76), Expect = 0.099
Identities = 42/200 (21%), Positives = 89/200 (44%), Gaps = 41/200 (20%)
Query: 22 LRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKL 81
L + +E++EEL + ++ + E+ VS ++ V K + E + K+K L + E++
Sbjct: 1499 LEEALEAKEEL-ERTNKMLKAEMEDLVSSKD--DVGKNVHELE----KSKRALETQMEEM 1551
Query: 82 QFALGEVEVLSKQLEKEKLAFEKALSSVK--------SKVLQESSKKDQLITKCNEIESH 133
+ L E+E + E KL E + ++K ++ Q K+ QL + +E E+
Sbjct: 1552 KTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETE 1611
Query: 134 I-------------------------IKQEDILNGKENEIKELQQVISQQKQIFRNHMSD 168
+ ++ + + G+E IK+L+++ +Q K F+ + D
Sbjct: 1612 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKD-FQRELED 1670
Query: 169 FRIQKQQESYMAQVLDQKHK 188
R + + A+ ++K K
Sbjct: 1671 ARASRDEIFATAKENEKKAK 1690
Score = 33.5 bits (75), Expect = 0.13
Identities = 31/134 (23%), Positives = 58/134 (43%), Gaps = 15/134 (11%)
Query: 50 KEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSV 109
+EE QA E +L + K + ++K + L E+E QL +EK ++ L +
Sbjct: 858 EEEMQAKEDELQKTK-----------ERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 906
Query: 110 KSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDF 169
+ + +L K E+E + + E L +E+ ++LQ +++ M D
Sbjct: 907 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ----AERKKMAQQMLDL 962
Query: 170 RIQKQQESYMAQVL 183
Q ++E Q L
Sbjct: 963 EEQLEEEEAARQKL 976
Score = 33.1 bits (74), Expect = 0.17
Identities = 40/189 (21%), Positives = 86/189 (45%), Gaps = 19/189 (10%)
Query: 27 ESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAH---AKTKVLLAKEEEKLQF 83
+S+++L V L++ ++E + + ++ E+ AA+ KTK L +E + L
Sbjct: 1382 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1441
Query: 84 ALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIK----QED 139
L L LEK++ F++ L+ K+ + + ++D+ + E E+ + E+
Sbjct: 1442 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1501
Query: 140 ILNGKE-----NEI--KELQQVISQQKQIFRN----HMSDFRIQKQQESYMAQVLDQKHK 188
L KE N++ E++ ++S + + +N S ++ Q E Q L++
Sbjct: 1502 ALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQ-LEELED 1560
Query: 189 KASGTRQAR 197
+ T A+
Sbjct: 1561 ELQATEDAK 1569
Score = 31.6 bits (70), Expect = 0.49
Identities = 42/209 (20%), Positives = 85/209 (40%), Gaps = 23/209 (11%)
Query: 18 ALDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEE---------KAAHA 68
A+ QLR + ++ +L + +DE F + +E + K L + A A
Sbjct: 1650 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1709
Query: 69 KTKVLLAKEE--EKLQFALG----------EVEVLSKQLEKEKLAFEKALSSVKSKVLQE 116
+ + L KEE E+L +L +E QLE+E + + ++ +V +
Sbjct: 1710 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1769
Query: 117 SSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQE 176
+ + +QL + S K E E + KEL+ + + + ++ E
Sbjct: 1770 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKS--TIAALE 1827
Query: 177 SYMAQVLDQKHKKASGTRQARSHQHPREK 205
+ +AQ+ +Q ++A + A ++K
Sbjct: 1828 AKIAQLEEQVEQEAREKQAATKSLKQKDK 1856
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 46.2 bits (108), Expect = 2e-05
Identities = 44/172 (25%), Positives = 80/172 (46%), Gaps = 17/172 (9%)
Query: 30 EELIHQLRNVMV--------LQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKL 81
EE++H++ + LQ E ++ +E++L EE+AA K ++ E K+
Sbjct: 928 EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKI 987
Query: 82 QFALGEVEVLSKQ---LEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQE 138
+ E+ V+ Q L KE+ E+ +S + + + +E K L N+ ES I + E
Sbjct: 988 KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE 1047
Query: 139 DILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKA 190
L +E +EL+++ K+ SDF +Q AQ+ + K + A
Sbjct: 1048 VRLKKEEKSRQELEKL----KRKLEGDASDF--HEQIADLQAQIAELKMQLA 1093
Score = 41.2 bits (95), Expect = 6e-04
Identities = 40/171 (23%), Positives = 77/171 (45%), Gaps = 8/171 (4%)
Query: 21 QLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEK 80
Q I+ +EE I QLR + + E+ +A ++ + K L + +
Sbjct: 1639 QADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQ 1698
Query: 81 LQFALGEVEVLSKQ--LEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQE 138
LQ L E KQ LEKE+LA E A S LQ+ +K +L + ++E + +++
Sbjct: 1699 LQEDLAAAERARKQADLEKEELAEELASSLSGRNALQD--EKRRLEARIAQLEEELEEEQ 1756
Query: 139 DILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
+ + +++ +QQ + N ++ R Q+ Q L++++K+
Sbjct: 1757 GNMEAMSDRVRK----ATQQAEQLSNELATERSTAQKNESARQQLERQNKE 1803
Score = 35.0 bits (79), Expect = 0.045
Identities = 30/196 (15%), Positives = 88/196 (44%), Gaps = 14/196 (7%)
Query: 20 DQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEE 79
+++ D+ + E + +N+ L++++ E + KK + + K K L +
Sbjct: 1013 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1072
Query: 80 KLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQED 139
+ +++ +L+ + E+ L + +++ E ++K+ + K E+E HI ++
Sbjct: 1073 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1132
Query: 140 ILNGK---ENEIKELQQVISQQKQIFRNHMSD----------FRIQKQQE-SYMAQVLDQ 185
L+ + N+ ++ ++ + ++ + + + D R +++QE + + + LD+
Sbjct: 1133 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1192
Query: 186 KHKKASGTRQARSHQH 201
+ + Q +H
Sbjct: 1193 ETRSHEAQVQEMRQKH 1208
Score = 34.7 bits (78), Expect = 0.058
Identities = 42/186 (22%), Positives = 86/186 (46%), Gaps = 20/186 (10%)
Query: 21 QLRDVIES----QEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAK 76
+L D ++S QE + + V VL+ EE ++ E ++ E + HA+ L +
Sbjct: 1161 ELEDTLDSTATQQELRAKREQEVTVLKK---ALDEETRSHEAQVQEMRQKHAQAVEELTE 1217
Query: 77 EEEKLQFALGEVEVLSKQLEKEK--LAFE-KALSSVKSKVLQESSKKD----QLITKCNE 129
+ E+ + A ++ + LEKE LA E + L K +V + K + +L +KC++
Sbjct: 1218 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1277
Query: 130 IESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
E + D ++ +NE++ + ++++ + ++ K S +Q+ D +
Sbjct: 1278 GERARAELNDKVHKLQNEVESVTGMLNEAEG------KAIKLAKDVASLSSQLQDTQELL 1331
Query: 190 ASGTRQ 195
TRQ
Sbjct: 1332 QEETRQ 1337
Score = 33.9 bits (76), Expect = 0.099
Identities = 42/200 (21%), Positives = 89/200 (44%), Gaps = 41/200 (20%)
Query: 22 LRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKL 81
L + +E++EEL + ++ + E+ VS ++ V K + E + K+K L + E++
Sbjct: 1499 LEEALEAKEEL-ERTNKMLKAEMEDLVSSKD--DVGKNVHELE----KSKRALETQMEEM 1551
Query: 82 QFALGEVEVLSKQLEKEKLAFEKALSSVK--------SKVLQESSKKDQLITKCNEIESH 133
+ L E+E + E KL E + ++K ++ Q K+ QL + +E E+
Sbjct: 1552 KTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETE 1611
Query: 134 I-------------------------IKQEDILNGKENEIKELQQVISQQKQIFRNHMSD 168
+ ++ + + G+E IK+L+++ +Q K F+ + D
Sbjct: 1612 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKD-FQRELED 1670
Query: 169 FRIQKQQESYMAQVLDQKHK 188
R + + A+ ++K K
Sbjct: 1671 ARASRDEIFATAKENEKKAK 1690
Score = 33.5 bits (75), Expect = 0.13
Identities = 31/134 (23%), Positives = 58/134 (43%), Gaps = 15/134 (11%)
Query: 50 KEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSV 109
+EE QA E +L + K + ++K + L E+E QL +EK ++ L +
Sbjct: 858 EEEMQAKEDELQKTK-----------ERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 906
Query: 110 KSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDF 169
+ + +L K E+E + + E L +E+ ++LQ +++ M D
Sbjct: 907 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ----AERKKMAQQMLDL 962
Query: 170 RIQKQQESYMAQVL 183
Q ++E Q L
Sbjct: 963 EEQLEEEEAARQKL 976
Score = 33.1 bits (74), Expect = 0.17
Identities = 40/189 (21%), Positives = 86/189 (45%), Gaps = 19/189 (10%)
Query: 27 ESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAH---AKTKVLLAKEEEKLQF 83
+S+++L V L++ ++E + + ++ E+ AA+ KTK L +E + L
Sbjct: 1382 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1441
Query: 84 ALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIK----QED 139
L L LEK++ F++ L+ K+ + + ++D+ + E E+ + E+
Sbjct: 1442 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1501
Query: 140 ILNGKE-----NEI--KELQQVISQQKQIFRN----HMSDFRIQKQQESYMAQVLDQKHK 188
L KE N++ E++ ++S + + +N S ++ Q E Q L++
Sbjct: 1502 ALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQ-LEELED 1560
Query: 189 KASGTRQAR 197
+ T A+
Sbjct: 1561 ELQATEDAK 1569
Score = 31.6 bits (70), Expect = 0.49
Identities = 42/209 (20%), Positives = 85/209 (40%), Gaps = 23/209 (11%)
Query: 18 ALDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEE---------KAAHA 68
A+ QLR + ++ +L + +DE F + +E + K L + A A
Sbjct: 1650 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1709
Query: 69 KTKVLLAKEE--EKLQFALG----------EVEVLSKQLEKEKLAFEKALSSVKSKVLQE 116
+ + L KEE E+L +L +E QLE+E + + ++ +V +
Sbjct: 1710 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1769
Query: 117 SSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQE 176
+ + +QL + S K E E + KEL+ + + + ++ E
Sbjct: 1770 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKS--TIAALE 1827
Query: 177 SYMAQVLDQKHKKASGTRQARSHQHPREK 205
+ +AQ+ +Q ++A + A ++K
Sbjct: 1828 AKIAQLEEQVEQEAREKQAATKSLKQKDK 1856
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 46.2 bits (108), Expect = 2e-05
Identities = 44/172 (25%), Positives = 80/172 (46%), Gaps = 17/172 (9%)
Query: 30 EELIHQLRNVMV--------LQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKL 81
EE++H++ + LQ E ++ +E++L EE+AA K ++ E K+
Sbjct: 921 EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKI 980
Query: 82 QFALGEVEVLSKQ---LEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQE 138
+ E+ V+ Q L KE+ E+ +S + + + +E K L N+ ES I + E
Sbjct: 981 KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE 1040
Query: 139 DILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKA 190
L +E +EL+++ K+ SDF +Q AQ+ + K + A
Sbjct: 1041 VRLKKEEKSRQELEKL----KRKLEGDASDF--HEQIADLQAQIAELKMQLA 1086
Score = 41.2 bits (95), Expect = 6e-04
Identities = 40/171 (23%), Positives = 77/171 (45%), Gaps = 8/171 (4%)
Query: 21 QLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEK 80
Q I+ +EE I QLR + + E+ +A ++ + K L + +
Sbjct: 1632 QADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQ 1691
Query: 81 LQFALGEVEVLSKQ--LEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQE 138
LQ L E KQ LEKE+LA E A S LQ+ +K +L + ++E + +++
Sbjct: 1692 LQEDLAAAERARKQADLEKEELAEELASSLSGRNALQD--EKRRLEARIAQLEEELEEEQ 1749
Query: 139 DILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
+ + +++ +QQ + N ++ R Q+ Q L++++K+
Sbjct: 1750 GNMEAMSDRVRK----ATQQAEQLSNELATERSTAQKNESARQQLERQNKE 1796
Score = 35.0 bits (79), Expect = 0.045
Identities = 30/196 (15%), Positives = 88/196 (44%), Gaps = 14/196 (7%)
Query: 20 DQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEE 79
+++ D+ + E + +N+ L++++ E + KK + + K K L +
Sbjct: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1065
Query: 80 KLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQED 139
+ +++ +L+ + E+ L + +++ E ++K+ + K E+E HI ++
Sbjct: 1066 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1125
Query: 140 ILNGK---ENEIKELQQVISQQKQIFRNHMSD----------FRIQKQQE-SYMAQVLDQ 185
L+ + N+ ++ ++ + ++ + + + D R +++QE + + + LD+
Sbjct: 1126 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1185
Query: 186 KHKKASGTRQARSHQH 201
+ + Q +H
Sbjct: 1186 ETRSHEAQVQEMRQKH 1201
Score = 34.7 bits (78), Expect = 0.058
Identities = 42/186 (22%), Positives = 86/186 (46%), Gaps = 20/186 (10%)
Query: 21 QLRDVIES----QEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAK 76
+L D ++S QE + + V VL+ EE ++ E ++ E + HA+ L +
Sbjct: 1154 ELEDTLDSTATQQELRAKREQEVTVLKK---ALDEETRSHEAQVQEMRQKHAQAVEELTE 1210
Query: 77 EEEKLQFALGEVEVLSKQLEKEK--LAFE-KALSSVKSKVLQESSKKD----QLITKCNE 129
+ E+ + A ++ + LEKE LA E + L K +V + K + +L +KC++
Sbjct: 1211 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1270
Query: 130 IESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
E + D ++ +NE++ + ++++ + ++ K S +Q+ D +
Sbjct: 1271 GERARAELNDKVHKLQNEVESVTGMLNEAEG------KAIKLAKDVASLSSQLQDTQELL 1324
Query: 190 ASGTRQ 195
TRQ
Sbjct: 1325 QEETRQ 1330
Score = 33.9 bits (76), Expect = 0.099
Identities = 42/200 (21%), Positives = 89/200 (44%), Gaps = 41/200 (20%)
Query: 22 LRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKL 81
L + +E++EEL + ++ + E+ VS ++ V K + E + K+K L + E++
Sbjct: 1492 LEEALEAKEEL-ERTNKMLKAEMEDLVSSKD--DVGKNVHELE----KSKRALETQMEEM 1544
Query: 82 QFALGEVEVLSKQLEKEKLAFEKALSSVK--------SKVLQESSKKDQLITKCNEIESH 133
+ L E+E + E KL E + ++K ++ Q K+ QL + +E E+
Sbjct: 1545 KTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETE 1604
Query: 134 I-------------------------IKQEDILNGKENEIKELQQVISQQKQIFRNHMSD 168
+ ++ + + G+E IK+L+++ +Q K F+ + D
Sbjct: 1605 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKD-FQRELED 1663
Query: 169 FRIQKQQESYMAQVLDQKHK 188
R + + A+ ++K K
Sbjct: 1664 ARASRDEIFATAKENEKKAK 1683
Score = 33.5 bits (75), Expect = 0.13
Identities = 31/134 (23%), Positives = 58/134 (43%), Gaps = 15/134 (11%)
Query: 50 KEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSV 109
+EE QA E +L + K + ++K + L E+E QL +EK ++ L +
Sbjct: 851 EEEMQAKEDELQKTK-----------ERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 899
Query: 110 KSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDF 169
+ + +L K E+E + + E L +E+ ++LQ +++ M D
Sbjct: 900 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ----AERKKMAQQMLDL 955
Query: 170 RIQKQQESYMAQVL 183
Q ++E Q L
Sbjct: 956 EEQLEEEEAARQKL 969
Score = 33.1 bits (74), Expect = 0.17
Identities = 40/189 (21%), Positives = 86/189 (45%), Gaps = 19/189 (10%)
Query: 27 ESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAH---AKTKVLLAKEEEKLQF 83
+S+++L V L++ ++E + + ++ E+ AA+ KTK L +E + L
Sbjct: 1375 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1434
Query: 84 ALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIK----QED 139
L L LEK++ F++ L+ K+ + + ++D+ + E E+ + E+
Sbjct: 1435 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1494
Query: 140 ILNGKE-----NEI--KELQQVISQQKQIFRN----HMSDFRIQKQQESYMAQVLDQKHK 188
L KE N++ E++ ++S + + +N S ++ Q E Q L++
Sbjct: 1495 ALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQ-LEELED 1553
Query: 189 KASGTRQAR 197
+ T A+
Sbjct: 1554 ELQATEDAK 1562
Score = 31.6 bits (70), Expect = 0.49
Identities = 42/209 (20%), Positives = 85/209 (40%), Gaps = 23/209 (11%)
Query: 18 ALDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEE---------KAAHA 68
A+ QLR + ++ +L + +DE F + +E + K L + A A
Sbjct: 1643 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1702
Query: 69 KTKVLLAKEE--EKLQFALG----------EVEVLSKQLEKEKLAFEKALSSVKSKVLQE 116
+ + L KEE E+L +L +E QLE+E + + ++ +V +
Sbjct: 1703 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762
Query: 117 SSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQE 176
+ + +QL + S K E E + KEL+ + + + ++ E
Sbjct: 1763 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKS--TIAALE 1820
Query: 177 SYMAQVLDQKHKKASGTRQARSHQHPREK 205
+ +AQ+ +Q ++A + A ++K
Sbjct: 1821 AKIAQLEEQVEQEAREKQAATKSLKQKDK 1849
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 45.8 bits (107), Expect = 3e-05
Identities = 44/193 (22%), Positives = 83/193 (43%), Gaps = 9/193 (4%)
Query: 19 LDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEE 78
L + R+ + ++ + Q R + E + +K L +EK A+ K LA+ +
Sbjct: 1798 LGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRK 1857
Query: 79 EKLQFALGEVEVLSKQL--EKEKLA-FEKALSSVKSKVLQESSKKDQLITKCNEIESHII 135
E L + + KQL K KL F K L+ V+ K+ QE + K E E ++
Sbjct: 1858 ENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLV 1917
Query: 136 KQEDILNGKENEIKE------LQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
+ ED L K+ ++ + L++ + Q K+ R + + +K M ++ ++K +
Sbjct: 1918 QVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRL 1977
Query: 190 ASGTRQARSHQHP 202
G + P
Sbjct: 1978 VEGKETLSKGETP 1990
Score = 42.0 bits (97), Expect = 4e-04
Identities = 43/136 (31%), Positives = 69/136 (50%), Gaps = 10/136 (7%)
Query: 29 QEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKL---QFAL 85
++EL +L + +E +EE E KLVEEK A+ + LA + EKL + L
Sbjct: 1711 EKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKL 1770
Query: 86 GEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKE 145
+ E L Q EKEKLA K + + L K++QLI K ++ K+E +N E
Sbjct: 1771 AQEEELLIQ-EKEKLAQHKEKMPEEEERL--GRKREQLIEKKMKLAQ---KRERWINSME 1824
Query: 146 NEIKELQQVISQQKQI 161
E+ + + ++ Q+K +
Sbjct: 1825 -ELTKNKMILYQKKNL 1839
Score = 41.2 bits (95), Expect = 6e-04
Identities = 38/175 (21%), Positives = 85/175 (48%), Gaps = 17/175 (9%)
Query: 24 DVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQF 83
+++ ++E L H + ++ ++++ + + VE+KL +EK K K LA+ E+KL
Sbjct: 1859 NLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQ 1918
Query: 84 ALGEVEVLSKQL--EKEKLAFEKALSSVKSK------VLQESSKKDQLITKCNEIESHII 135
+ ++L EK KLA EKA+ K + + +E + + + E + ++
Sbjct: 1919 VEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLV 1978
Query: 136 K-QEDILNGKENEIKELQQVISQQKQIFRNHMS--------DFRIQKQQESYMAQ 181
+ +E + G+ E +++ ++++F +S + RI +ES +A+
Sbjct: 1979 EGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAK 2033
Score = 38.1 bits (87), Expect = 0.005
Identities = 38/180 (21%), Positives = 82/180 (45%), Gaps = 9/180 (5%)
Query: 19 LDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEE 78
L Q + + + E + Q R + + E +EE KL ++ A+ K +LA++
Sbjct: 1644 LAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEE------KLAKKGGKLAEVKNILAQKV 1697
Query: 79 EKLQFALGEVEVLSKQLEKEKLAFE---KALSSVKSKVLQESSKKDQLITKCNEIESHII 135
E+L ++ K+L +E E + LS + ++ QE K + K E E +
Sbjct: 1698 EELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALA 1757
Query: 136 KQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKASGTRQ 195
Q + L+ +E ++ + ++++ Q+K+ H ++++ + L +K K + R+
Sbjct: 1758 WQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRE 1817
Score = 37.7 bits (86), Expect = 0.007
Identities = 45/190 (23%), Positives = 81/190 (42%), Gaps = 23/190 (12%)
Query: 23 RDVIESQEELIHQLRNVMVLQDENFVSKEE---FQAVEKKLVEEKAAHAKTKVL------ 73
RD+ E EE+ L +V Q+ V E +Q +K E K H +T+
Sbjct: 1425 RDMSEEVEEMA-TLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKE 1483
Query: 74 -----LAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCN 128
L +EEEKL A ++ + L+++K + V +L SK+ Q
Sbjct: 1484 EWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQY----- 1538
Query: 129 EIESHIIKQEDIL---NGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQ 185
+ E + +E++ KE ++ E Q+ I ++ + R H R +K++ ++ +
Sbjct: 1539 KDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQE 1598
Query: 186 KHKKASGTRQ 195
+ K A RQ
Sbjct: 1599 EEKLAQEERQ 1608
Score = 37.7 bits (86), Expect = 0.007
Identities = 31/132 (23%), Positives = 66/132 (50%), Gaps = 6/132 (4%)
Query: 57 EKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAF---EKALSSVKSKV 113
E+KL +E+ A+ + LA+EE KL A ++ +++ + + F E+ L+ K+
Sbjct: 1592 ERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKL 1651
Query: 114 LQESSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQK 173
QE+ K Q K + + ++E+ L K ++ E++ +++Q+ + +
Sbjct: 1652 SQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNL---D 1708
Query: 174 QQESYMAQVLDQ 185
QE +AQ L++
Sbjct: 1709 WQEKELAQELEE 1720
Score = 37.4 bits (85), Expect = 0.009
Identities = 36/155 (23%), Positives = 81/155 (52%), Gaps = 19/155 (12%)
Query: 24 DVIESQEELIHQLRNVM--VLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEE-EK 80
D +ES+E ++ +++ + + E+ S+EE + E++ EE+ + + +EE E+
Sbjct: 2218 DEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEE 2277
Query: 81 LQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDI 140
Q E E K+ EK+K ++ K +V +E K++++ +E E+ + E+
Sbjct: 2278 KQVEKEEEEKKKKKKEKKKEEVQE-----KEEVFEE---KEEIM---SEEETESLSDEE- 2325
Query: 141 LNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQ 175
+E E L++ + ++K+I + F++Q+Q+
Sbjct: 2326 ---EEEESCSLEEEVDREKEILKKE-KQFKLQEQR 2356
Score = 34.7 bits (78), Expect = 0.058
Identities = 41/170 (24%), Positives = 76/170 (44%), Gaps = 16/170 (9%)
Query: 29 QEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEV 88
+EE +HQ + ++E ++ + E K V E +K+K K+EE++ E
Sbjct: 1492 EEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTL---EE 1548
Query: 89 EVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENEI 148
EV + EKE+ E + + +QE K ++ K E ++E L +E ++
Sbjct: 1549 EVSREGEEKEQQVTE------EQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKL 1602
Query: 149 KELQQVISQQK----QIFRNHMSDFRIQKQQESYMAQ---VLDQKHKKAS 191
+ ++ ++Q++ Q + D R Q E AQ L Q+ +K S
Sbjct: 1603 AQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLS 1652
Score = 34.7 bits (78), Expect = 0.058
Identities = 37/151 (24%), Positives = 72/151 (47%), Gaps = 7/151 (4%)
Query: 17 LALDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAK 76
+ L Q +++ + ++ L + + ++ +KE +K+LV+ K +LA+
Sbjct: 1831 MILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQ 1890
Query: 77 EEEKLQFALGEVEVLSKQLEKEKLA-FEKALSSVKSKVLQESSKKDQLITKCNEIESHII 135
EEKL E E + K +KEKLA EK L V+ + ++ K Q K +E ++
Sbjct: 1891 VEEKL---TQEKETVIK--KKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKL-ALEKAMV 1944
Query: 136 KQEDILNGKENEIKELQQVISQQKQIFRNHM 166
+ + L G+ + KE + + + K++ M
Sbjct: 1945 QGKKRLRGELDIAKEEKALNLEMKRLAEEKM 1975
Score = 27.3 bits (59), Expect = 9.3
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 6/83 (7%)
Query: 44 DENFVSKEEFQAVEKKL------VEEKAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEK 97
+E V KEE + +KK V+EK + K + EEE + E E S LE+
Sbjct: 2276 EEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEE 2335
Query: 98 EKLAFEKALSSVKSKVLQESSKK 120
E ++ L K LQE +K
Sbjct: 2336 EVDREKEILKKEKQFKLQEQRRK 2358
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 45.8 bits (107), Expect = 3e-05
Identities = 41/182 (22%), Positives = 82/182 (45%), Gaps = 5/182 (2%)
Query: 24 DVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQF 83
+V ESQE H+ ++E+ + E +EKA + + E Q
Sbjct: 587 EVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQK 646
Query: 84 ALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHI-IKQEDILN 142
+ E+E K+L+ K +E+ L ++ K+ ++DQ++ +ES+ K + + +
Sbjct: 647 LIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRS 706
Query: 143 GKENEI----KELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKASGTRQARS 198
E ++ KELQ++ + QK+ R + + +KQ + V++ K K +Q +
Sbjct: 707 EYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKE 766
Query: 199 HQ 200
Q
Sbjct: 767 EQ 768
>gi|90819229 cutaneous T-cell lymphoma-associated antigen 1 isoform
1 [Homo sapiens]
Length = 745
Score = 45.4 bits (106), Expect = 3e-05
Identities = 34/132 (25%), Positives = 61/132 (46%), Gaps = 24/132 (18%)
Query: 52 EFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSS--- 108
E +EK+L EEK+ H++ L+A +++Q E + L Q+ + K+ F++ ++
Sbjct: 114 EILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEER 173
Query: 109 ---------VKSKVLQESSKK------------DQLITKCNEIESHIIKQEDILNGKENE 147
++ LQES K+ +LI + E + E +LN KEN
Sbjct: 174 LEIEIQDAWKENSELQESQKQLLQEAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENH 233
Query: 148 IKELQQVISQQK 159
IK L + + + K
Sbjct: 234 IKTLTERLLKMK 245
Score = 33.5 bits (75), Expect = 0.13
Identities = 34/146 (23%), Positives = 67/146 (45%), Gaps = 37/146 (25%)
Query: 21 QLRDVIESQEELIHQLRNVMV----LQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAK 76
QL +V +++EEL ++N+ LQ EN + E Q +++KL KV+
Sbjct: 309 QLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKL----------KVMTEL 358
Query: 77 EEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIK 136
+E E+++ K + +EK EK ++ ++K +E+ SH +
Sbjct: 359 YQEN------EMKLYRKLIVEEKCRLEK----------------EEKLSKVDEMISHATE 396
Query: 137 QEDILNGKENEIKELQQVIS-QQKQI 161
+ + + ++KE ++ I QK+I
Sbjct: 397 ELETYRKRAKDLKEFEKTIHFYQKKI 422
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 45.4 bits (106), Expect = 3e-05
Identities = 38/161 (23%), Positives = 76/161 (47%), Gaps = 3/161 (1%)
Query: 45 ENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEK 104
EN KEE + + ++ VEE +V L K EE+L+ L E + + E++K E+
Sbjct: 539 ENLRRKEEAEQLRRQKVEEDKRRRLEEVKL-KREERLRKVLQARERVEQMKEEKKKQIEQ 597
Query: 105 ALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRN 164
+ + K E +K+++L + + ++ K E++ ++ E + + QQ++ R
Sbjct: 598 KFAQIDEKT--EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERR 655
Query: 165 HMSDFRIQKQQESYMAQVLDQKHKKASGTRQARSHQHPREK 205
H + +K++E + + + A Q R Q RE+
Sbjct: 656 HQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQ 696
Score = 42.7 bits (99), Expect = 2e-04
Identities = 38/184 (20%), Positives = 86/184 (46%), Gaps = 9/184 (4%)
Query: 29 QEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFA--LG 86
++E QLR V +D+ +E E++L K A+ +V KEE+K Q
Sbjct: 543 RKEEAEQLRRQKVEEDKRRRLEEVKLKREERL--RKVLQARERVEQMKEEKKKQIEQKFA 600
Query: 87 EVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEI-----ESHIIKQEDIL 141
+++ +++ ++E+LA EKA +K ++E + + + + E + +++L
Sbjct: 601 QIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELL 660
Query: 142 NGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKASGTRQARSHQH 201
K+ E +E + ++ K++ + R Q+++E + ++ ++ RQ +
Sbjct: 661 QKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQER 720
Query: 202 PREK 205
RE+
Sbjct: 721 RREQ 724
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 45.1 bits (105), Expect = 4e-05
Identities = 38/164 (23%), Positives = 76/164 (46%), Gaps = 14/164 (8%)
Query: 26 IESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFAL 85
I QEE I + M Q+E +E+ + EK+ +E+ + ++EEK++
Sbjct: 486 IREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEE---------MWRQEEKIR--- 533
Query: 86 GEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKE 145
E E + +Q EK EK + QE DQ K E E + +QE+ + +E
Sbjct: 534 -EQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQ-EEKIREQEEKVWRQEEKIREQE 591
Query: 146 NEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
+I+E ++ I +Q+++ + Q+++ + + ++ +K
Sbjct: 592 EKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEK 635
Score = 44.3 bits (103), Expect = 7e-05
Identities = 37/167 (22%), Positives = 84/167 (50%), Gaps = 15/167 (8%)
Query: 19 LDQLRDVIESQEELIHQLRNVMVLQDENFVSKEE-FQAVEKKLVEEKAAHAKTKVLLAKE 77
+ + + I QEE I + M Q+E KEE + E+ + E++ + + ++ ++
Sbjct: 377 IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK 436
Query: 78 EEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLIT------KCNEIE 131
EEK++ E+ K E+EK+ ++ + K+ ++ +++Q K E E
Sbjct: 437 EEKIR------ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 490
Query: 132 SHIIKQEDILNGKENEIKELQQVISQQKQIFRNHM--SDFRIQKQQE 176
I +QE+ + +E +I E +++ ++K+ + M + +I++Q+E
Sbjct: 491 EKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 537
Score = 42.4 bits (98), Expect = 3e-04
Identities = 39/192 (20%), Positives = 89/192 (46%), Gaps = 11/192 (5%)
Query: 20 DQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEE 79
+++ + + +EE Q + M Q+E +EE ++K+ E++ K + + ++EE
Sbjct: 505 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEE 564
Query: 80 KLQFALGEVEVLSKQLEK-----EKL-AFEKALSSVKSKVLQESSKKDQLITKCNEIESH 133
K+ + E + +Q EK EK+ E+ + + K+ ++ + K E E
Sbjct: 565 KMH---DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 621
Query: 134 IIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKASGT 193
+ +QE+ + +E +++ ++ I +Q++ R + +I++Q+E Q ++
Sbjct: 622 MCEQEEKMQEQEEKMRRQEEKIREQEKKIRE--QEEKIREQEEMMQEQEEKMWEQEEKMC 679
Query: 194 RQARSHQHPREK 205
Q Q EK
Sbjct: 680 EQEEKMQEQEEK 691
Score = 39.7 bits (91), Expect = 0.002
Identities = 43/197 (21%), Positives = 87/197 (44%), Gaps = 22/197 (11%)
Query: 30 EELIHQLRNVMVLQDENFVSKEEFQAVEKKLVE--EKAAHAKTKVLLAKEEEKLQFALGE 87
EEL + + + N ++ EE + KL E + K+++ L +E K + +
Sbjct: 257 EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK 316
Query: 88 VEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCN---------------EIES 132
+ + +QL+ E K L SV +K LQ ++++L + N E E
Sbjct: 317 LLLPQQQLQAEADHLGKELQSVSAK-LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEE 375
Query: 133 HIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQK----QQESYMAQVLDQKHK 188
I +QE+ + +E +I+E ++ + +Q+++ R Q+ ++E M + + +
Sbjct: 376 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 435
Query: 189 KASGTRQARSHQHPREK 205
K R+ H +EK
Sbjct: 436 KEEKIRELEEKMHEQEK 452
Score = 36.6 bits (83), Expect = 0.015
Identities = 28/138 (20%), Positives = 68/138 (49%), Gaps = 5/138 (3%)
Query: 29 QEELIHQLRNVMVLQDENFVSKEEF-QAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGE 87
QEE I + + Q+E +EE Q E+K+ E++ + + + ++EEK++ +
Sbjct: 583 QEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEK 642
Query: 88 VEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENE 147
+ K++ ++ E+ + + + ++ K + K E E + +QE+ + +E +
Sbjct: 643 IREQEKKIREQ----EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 698
Query: 148 IKELQQVISQQKQIFRNH 165
+ E + + QQ++ + H
Sbjct: 699 MWEQEVRLRQQEEKMQEH 716
Score = 33.9 bits (76), Expect = 0.099
Identities = 32/193 (16%), Positives = 91/193 (47%), Gaps = 14/193 (7%)
Query: 27 ESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKL----- 81
+ +E++ Q + +++ +E+ + E+K+ E++ + + ++ ++EEK+
Sbjct: 358 QQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE 417
Query: 82 ------QFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLI---TKCNEIES 132
+ + E++ ++ EK + EK K + +E ++++ I K E E+
Sbjct: 418 MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 477
Query: 133 HIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKASG 192
+ +QE+ + +E +I+E ++ + +Q++ +K+QE ++K ++
Sbjct: 478 KMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 537
Query: 193 TRQARSHQHPREK 205
+ + H +E+
Sbjct: 538 IWRQKEKIHEQEE 550
Score = 30.8 bits (68), Expect = 0.84
Identities = 18/58 (31%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Query: 26 IESQEELIHQLRNVMVLQDENFVSKEE-FQAVEKKLVEEKAAHAKTKVLLAKEEEKLQ 82
I QEE++ + M Q+E +EE Q E+K+ ++ + +V L ++EEK+Q
Sbjct: 657 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 714
Score = 27.3 bits (59), Expect = 9.3
Identities = 21/94 (22%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 19 LDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEF-QAVEKKLVEEKAAHAKTKVLLAKE 77
+ + + + QEE I + + Q+E +EE Q E+K+ E++ + + + ++
Sbjct: 629 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 688
Query: 78 EEKL---QFALGEVEVLSKQLEKEKLAFEKALSS 108
EEK+ + + E EV +Q E++ ++ L +
Sbjct: 689 EEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 45.1 bits (105), Expect = 4e-05
Identities = 31/130 (23%), Positives = 73/130 (56%), Gaps = 10/130 (7%)
Query: 77 EEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIK 136
+ E+L+ A+ E+E EKEKL E L +KS+ +Q + +++QL+ + ++ +
Sbjct: 2444 DAERLREAIAELE-----REKEKLQQEAKLLQLKSEEMQ-TVQQEQLLQETQALQQSFLS 2497
Query: 137 QEDILNGKENEIKELQQVISQQKQIFRNHMSDFR-IQKQQESYMAQVLDQKHKKASGTRQ 195
++D L +E I +Q ++ +Q+F++ ++ + ++++Q+ Q+ ++ + + +
Sbjct: 2498 EKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEE 2554
Query: 196 ARSHQHPREK 205
AR QH E+
Sbjct: 2555 ARRRQHEAEE 2564
Score = 40.0 bits (92), Expect = 0.001
Identities = 35/180 (19%), Positives = 84/180 (46%), Gaps = 26/180 (14%)
Query: 20 DQLRDVI---ESQEELIHQLRNVMVLQDENFVSKE------EFQAVEKKLVEEKAAHAKT 70
++LR+ I E ++E + Q ++ L+ E + + E QA+++ + EK + +
Sbjct: 2446 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2505
Query: 71 KVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEI 130
+ + +E+ KL+ + ++QL +E+ ++ Q ++ +L+ E
Sbjct: 2506 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQ----------QMEQERQRLVASMEEA 2555
Query: 131 ESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKA 190
+ E+ + K+ E+++L+Q QQ+++ R Q Q+L+++H+ A
Sbjct: 2556 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQ-------LQLLEEQHRAA 2608
Score = 34.7 bits (78), Expect = 0.058
Identities = 36/202 (17%), Positives = 85/202 (42%), Gaps = 29/202 (14%)
Query: 9 KAGSGSVCLALDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHA 68
KA + +V +L+ ++ ++ ++ QLR E +A + E + A
Sbjct: 2052 KAHAFAVQQKEQELQQTLQQEQSVLDQLRG-------------EAEAARRAAEEAEEARV 2098
Query: 69 KTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLA---FEKALSSVKSKVLQESSKKDQLIT 125
+ + A+ +++ E E L + E++ A + A ++ + QE++++ Q
Sbjct: 2099 QAEREAAQSRRQVE----EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA-- 2152
Query: 126 KCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQ 185
E ++Q+ + + + K+ + +QK ++ R+Q ++ + +LD+
Sbjct: 2153 -----EQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDE 2207
Query: 186 --KHKKASGTRQARSHQHPREK 205
+ KA T AR E+
Sbjct: 2208 ELQRLKAEATEAARQRSQVEEE 2229
Score = 33.1 bits (74), Expect = 0.17
Identities = 44/214 (20%), Positives = 93/214 (43%), Gaps = 30/214 (14%)
Query: 1 MATPLGWSKAGSGSVCLALDQLR------DVIESQEEL-IHQLRNVMVLQDENFVSKEEF 53
+A + KA +G L L+ R D + S+E+ + R + +E +E
Sbjct: 1928 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1987
Query: 54 QAVEKKLVEE-------KAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKAL 106
+ V+K L E KAA + + L AK EE + + ++QL+ + A +K L
Sbjct: 1988 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2047
Query: 107 SSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHM 166
+ + +K+Q E++ + +++ +L+ E + ++ + ++
Sbjct: 2048 QAEEKAHAFAVQQKEQ------ELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA----- 2096
Query: 167 SDFRIQKQQESYMA--QVLDQKHKKASGTRQARS 198
R+Q ++E+ + QV + + K S QA++
Sbjct: 2097 ---RVQAEREAAQSRRQVEEAERLKQSAEEQAQA 2127
Score = 32.7 bits (73), Expect = 0.22
Identities = 31/166 (18%), Positives = 78/166 (46%), Gaps = 14/166 (8%)
Query: 30 EELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVE 89
+E + ++ + + + ++ E + +L EK + LL + E++Q
Sbjct: 2425 QEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQ------T 2478
Query: 90 VLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEI-ESHIIKQEDILNGKENEI 148
V +QL +E A +++ S K +LQ +Q K ++ + + K + + ++ +
Sbjct: 2479 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ 2538
Query: 149 KELQQ-----VISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
++++Q V S ++ R H ++ ++++QE Q L+Q+ ++
Sbjct: 2539 QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEE--LQQLEQQRRQ 2582
Score = 31.6 bits (70), Expect = 0.49
Identities = 45/199 (22%), Positives = 85/199 (42%), Gaps = 27/199 (13%)
Query: 27 ESQEELIHQLRNVMVLQDENFVSKE-EFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFAL 85
++QEE R V QDE+ ++ E + + E +AA K + L A EE +LQ
Sbjct: 1491 QAQEEAERLRRQV---QDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1547
Query: 86 GEVEVLSKQLEKEK---LAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQE-DIL 141
E + ++E+ + +A E A S ++++ SK+ K ++E + ++ +
Sbjct: 1548 AERRLRQAEVERARQVQVALETAQRSAEAEL---QSKRASFAEKTAQLERSLQEEHVAVA 1604
Query: 142 NGKENEIKELQQVISQQK------------QIFRNHMSDFRIQKQ---QESYMAQVLDQK 186
+E + QQ ++ Q+ N R+Q + Q+ +AQ +K
Sbjct: 1605 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1664
Query: 187 HKKASGTRQARSHQHPREK 205
K+ R+AR E+
Sbjct: 1665 QKE-EAEREARRRGKAEEQ 1682
Score = 28.9 bits (63), Expect = 3.2
Identities = 29/155 (18%), Positives = 71/155 (45%), Gaps = 13/155 (8%)
Query: 29 QEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEV 88
QEE++ + + Q + +EE Q + + E AK + A E +L+ E+
Sbjct: 1398 QEEVVRREEAAVDAQQQKRSIQEELQQLRQS--SEAEIQAKARQAEAAERSRLRIE-EEI 1454
Query: 89 EVLSKQL---EKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKE 145
V+ QL E+++ E L +++++ + ++K Q + + + Q++ ++
Sbjct: 1455 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQV--QDESQRKRQ 1512
Query: 146 NEIKELQQV-----ISQQKQIFRNHMSDFRIQKQQ 175
E++ +V +++KQ + + R+Q ++
Sbjct: 1513 AEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1547
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 45.1 bits (105), Expect = 4e-05
Identities = 31/130 (23%), Positives = 73/130 (56%), Gaps = 10/130 (7%)
Query: 77 EEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIK 136
+ E+L+ A+ E+E EKEKL E L +KS+ +Q + +++QL+ + ++ +
Sbjct: 2448 DAERLREAIAELE-----REKEKLQQEAKLLQLKSEEMQ-TVQQEQLLQETQALQQSFLS 2501
Query: 137 QEDILNGKENEIKELQQVISQQKQIFRNHMSDFR-IQKQQESYMAQVLDQKHKKASGTRQ 195
++D L +E I +Q ++ +Q+F++ ++ + ++++Q+ Q+ ++ + + +
Sbjct: 2502 EKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEE 2558
Query: 196 ARSHQHPREK 205
AR QH E+
Sbjct: 2559 ARRRQHEAEE 2568
Score = 40.0 bits (92), Expect = 0.001
Identities = 35/180 (19%), Positives = 84/180 (46%), Gaps = 26/180 (14%)
Query: 20 DQLRDVI---ESQEELIHQLRNVMVLQDENFVSKE------EFQAVEKKLVEEKAAHAKT 70
++LR+ I E ++E + Q ++ L+ E + + E QA+++ + EK + +
Sbjct: 2450 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2509
Query: 71 KVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEI 130
+ + +E+ KL+ + ++QL +E+ ++ Q ++ +L+ E
Sbjct: 2510 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQ----------QMEQERQRLVASMEEA 2559
Query: 131 ESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKA 190
+ E+ + K+ E+++L+Q QQ+++ R Q Q+L+++H+ A
Sbjct: 2560 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQ-------LQLLEEQHRAA 2612
Score = 34.7 bits (78), Expect = 0.058
Identities = 36/202 (17%), Positives = 85/202 (42%), Gaps = 29/202 (14%)
Query: 9 KAGSGSVCLALDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHA 68
KA + +V +L+ ++ ++ ++ QLR E +A + E + A
Sbjct: 2056 KAHAFAVQQKEQELQQTLQQEQSVLDQLRG-------------EAEAARRAAEEAEEARV 2102
Query: 69 KTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLA---FEKALSSVKSKVLQESSKKDQLIT 125
+ + A+ +++ E E L + E++ A + A ++ + QE++++ Q
Sbjct: 2103 QAEREAAQSRRQVE----EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA-- 2156
Query: 126 KCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQ 185
E ++Q+ + + + K+ + +QK ++ R+Q ++ + +LD+
Sbjct: 2157 -----EQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDE 2211
Query: 186 --KHKKASGTRQARSHQHPREK 205
+ KA T AR E+
Sbjct: 2212 ELQRLKAEATEAARQRSQVEEE 2233
Score = 33.1 bits (74), Expect = 0.17
Identities = 44/214 (20%), Positives = 93/214 (43%), Gaps = 30/214 (14%)
Query: 1 MATPLGWSKAGSGSVCLALDQLR------DVIESQEEL-IHQLRNVMVLQDENFVSKEEF 53
+A + KA +G L L+ R D + S+E+ + R + +E +E
Sbjct: 1932 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1991
Query: 54 QAVEKKLVEE-------KAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKAL 106
+ V+K L E KAA + + L AK EE + + ++QL+ + A +K L
Sbjct: 1992 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2051
Query: 107 SSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHM 166
+ + +K+Q E++ + +++ +L+ E + ++ + ++
Sbjct: 2052 QAEEKAHAFAVQQKEQ------ELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA----- 2100
Query: 167 SDFRIQKQQESYMA--QVLDQKHKKASGTRQARS 198
R+Q ++E+ + QV + + K S QA++
Sbjct: 2101 ---RVQAEREAAQSRRQVEEAERLKQSAEEQAQA 2131
Score = 32.7 bits (73), Expect = 0.22
Identities = 31/166 (18%), Positives = 78/166 (46%), Gaps = 14/166 (8%)
Query: 30 EELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVE 89
+E + ++ + + + ++ E + +L EK + LL + E++Q
Sbjct: 2429 QEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQ------T 2482
Query: 90 VLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEI-ESHIIKQEDILNGKENEI 148
V +QL +E A +++ S K +LQ +Q K ++ + + K + + ++ +
Sbjct: 2483 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ 2542
Query: 149 KELQQ-----VISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
++++Q V S ++ R H ++ ++++QE Q L+Q+ ++
Sbjct: 2543 QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEE--LQQLEQQRRQ 2586
Score = 31.6 bits (70), Expect = 0.49
Identities = 45/199 (22%), Positives = 85/199 (42%), Gaps = 27/199 (13%)
Query: 27 ESQEELIHQLRNVMVLQDENFVSKE-EFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFAL 85
++QEE R V QDE+ ++ E + + E +AA K + L A EE +LQ
Sbjct: 1495 QAQEEAERLRRQV---QDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1551
Query: 86 GEVEVLSKQLEKEK---LAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQE-DIL 141
E + ++E+ + +A E A S ++++ SK+ K ++E + ++ +
Sbjct: 1552 AERRLRQAEVERARQVQVALETAQRSAEAEL---QSKRASFAEKTAQLERSLQEEHVAVA 1608
Query: 142 NGKENEIKELQQVISQQK------------QIFRNHMSDFRIQKQ---QESYMAQVLDQK 186
+E + QQ ++ Q+ N R+Q + Q+ +AQ +K
Sbjct: 1609 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1668
Query: 187 HKKASGTRQARSHQHPREK 205
K+ R+AR E+
Sbjct: 1669 QKE-EAEREARRRGKAEEQ 1686
Score = 28.9 bits (63), Expect = 3.2
Identities = 29/155 (18%), Positives = 71/155 (45%), Gaps = 13/155 (8%)
Query: 29 QEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEV 88
QEE++ + + Q + +EE Q + + E AK + A E +L+ E+
Sbjct: 1402 QEEVVRREEAAVDAQQQKRSIQEELQQLRQS--SEAEIQAKARQAEAAERSRLRIE-EEI 1458
Query: 89 EVLSKQL---EKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKE 145
V+ QL E+++ E L +++++ + ++K Q + + + Q++ ++
Sbjct: 1459 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQV--QDESQRKRQ 1516
Query: 146 NEIKELQQV-----ISQQKQIFRNHMSDFRIQKQQ 175
E++ +V +++KQ + + R+Q ++
Sbjct: 1517 AEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1551
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 45.1 bits (105), Expect = 4e-05
Identities = 31/130 (23%), Positives = 73/130 (56%), Gaps = 10/130 (7%)
Query: 77 EEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIK 136
+ E+L+ A+ E+E EKEKL E L +KS+ +Q + +++QL+ + ++ +
Sbjct: 2444 DAERLREAIAELE-----REKEKLQQEAKLLQLKSEEMQ-TVQQEQLLQETQALQQSFLS 2497
Query: 137 QEDILNGKENEIKELQQVISQQKQIFRNHMSDFR-IQKQQESYMAQVLDQKHKKASGTRQ 195
++D L +E I +Q ++ +Q+F++ ++ + ++++Q+ Q+ ++ + + +
Sbjct: 2498 EKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEE 2554
Query: 196 ARSHQHPREK 205
AR QH E+
Sbjct: 2555 ARRRQHEAEE 2564
Score = 40.0 bits (92), Expect = 0.001
Identities = 35/180 (19%), Positives = 84/180 (46%), Gaps = 26/180 (14%)
Query: 20 DQLRDVI---ESQEELIHQLRNVMVLQDENFVSKE------EFQAVEKKLVEEKAAHAKT 70
++LR+ I E ++E + Q ++ L+ E + + E QA+++ + EK + +
Sbjct: 2446 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2505
Query: 71 KVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEI 130
+ + +E+ KL+ + ++QL +E+ ++ Q ++ +L+ E
Sbjct: 2506 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQ----------QMEQERQRLVASMEEA 2555
Query: 131 ESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKA 190
+ E+ + K+ E+++L+Q QQ+++ R Q Q+L+++H+ A
Sbjct: 2556 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQ-------LQLLEEQHRAA 2608
Score = 34.7 bits (78), Expect = 0.058
Identities = 36/202 (17%), Positives = 85/202 (42%), Gaps = 29/202 (14%)
Query: 9 KAGSGSVCLALDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHA 68
KA + +V +L+ ++ ++ ++ QLR E +A + E + A
Sbjct: 2052 KAHAFAVQQKEQELQQTLQQEQSVLDQLRG-------------EAEAARRAAEEAEEARV 2098
Query: 69 KTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLA---FEKALSSVKSKVLQESSKKDQLIT 125
+ + A+ +++ E E L + E++ A + A ++ + QE++++ Q
Sbjct: 2099 QAEREAAQSRRQVE----EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA-- 2152
Query: 126 KCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQ 185
E ++Q+ + + + K+ + +QK ++ R+Q ++ + +LD+
Sbjct: 2153 -----EQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDE 2207
Query: 186 --KHKKASGTRQARSHQHPREK 205
+ KA T AR E+
Sbjct: 2208 ELQRLKAEATEAARQRSQVEEE 2229
Score = 33.1 bits (74), Expect = 0.17
Identities = 44/214 (20%), Positives = 93/214 (43%), Gaps = 30/214 (14%)
Query: 1 MATPLGWSKAGSGSVCLALDQLR------DVIESQEEL-IHQLRNVMVLQDENFVSKEEF 53
+A + KA +G L L+ R D + S+E+ + R + +E +E
Sbjct: 1928 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1987
Query: 54 QAVEKKLVEE-------KAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKAL 106
+ V+K L E KAA + + L AK EE + + ++QL+ + A +K L
Sbjct: 1988 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2047
Query: 107 SSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHM 166
+ + +K+Q E++ + +++ +L+ E + ++ + ++
Sbjct: 2048 QAEEKAHAFAVQQKEQ------ELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA----- 2096
Query: 167 SDFRIQKQQESYMA--QVLDQKHKKASGTRQARS 198
R+Q ++E+ + QV + + K S QA++
Sbjct: 2097 ---RVQAEREAAQSRRQVEEAERLKQSAEEQAQA 2127
Score = 32.7 bits (73), Expect = 0.22
Identities = 31/166 (18%), Positives = 78/166 (46%), Gaps = 14/166 (8%)
Query: 30 EELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVE 89
+E + ++ + + + ++ E + +L EK + LL + E++Q
Sbjct: 2425 QEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQ------T 2478
Query: 90 VLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEI-ESHIIKQEDILNGKENEI 148
V +QL +E A +++ S K +LQ +Q K ++ + + K + + ++ +
Sbjct: 2479 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ 2538
Query: 149 KELQQ-----VISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
++++Q V S ++ R H ++ ++++QE Q L+Q+ ++
Sbjct: 2539 QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEE--LQQLEQQRRQ 2582
Score = 31.6 bits (70), Expect = 0.49
Identities = 45/199 (22%), Positives = 85/199 (42%), Gaps = 27/199 (13%)
Query: 27 ESQEELIHQLRNVMVLQDENFVSKE-EFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFAL 85
++QEE R V QDE+ ++ E + + E +AA K + L A EE +LQ
Sbjct: 1491 QAQEEAERLRRQV---QDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1547
Query: 86 GEVEVLSKQLEKEK---LAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQE-DIL 141
E + ++E+ + +A E A S ++++ SK+ K ++E + ++ +
Sbjct: 1548 AERRLRQAEVERARQVQVALETAQRSAEAEL---QSKRASFAEKTAQLERSLQEEHVAVA 1604
Query: 142 NGKENEIKELQQVISQQK------------QIFRNHMSDFRIQKQ---QESYMAQVLDQK 186
+E + QQ ++ Q+ N R+Q + Q+ +AQ +K
Sbjct: 1605 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1664
Query: 187 HKKASGTRQARSHQHPREK 205
K+ R+AR E+
Sbjct: 1665 QKE-EAEREARRRGKAEEQ 1682
Score = 28.9 bits (63), Expect = 3.2
Identities = 29/155 (18%), Positives = 71/155 (45%), Gaps = 13/155 (8%)
Query: 29 QEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEV 88
QEE++ + + Q + +EE Q + + E AK + A E +L+ E+
Sbjct: 1398 QEEVVRREEAAVDAQQQKRSIQEELQQLRQS--SEAEIQAKARQAEAAERSRLRIE-EEI 1454
Query: 89 EVLSKQL---EKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKE 145
V+ QL E+++ E L +++++ + ++K Q + + + Q++ ++
Sbjct: 1455 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQV--QDESQRKRQ 1512
Query: 146 NEIKELQQV-----ISQQKQIFRNHMSDFRIQKQQ 175
E++ +V +++KQ + + R+Q ++
Sbjct: 1513 AEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1547
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 45.1 bits (105), Expect = 4e-05
Identities = 31/130 (23%), Positives = 73/130 (56%), Gaps = 10/130 (7%)
Query: 77 EEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIK 136
+ E+L+ A+ E+E EKEKL E L +KS+ +Q + +++QL+ + ++ +
Sbjct: 2412 DAERLREAIAELE-----REKEKLQQEAKLLQLKSEEMQ-TVQQEQLLQETQALQQSFLS 2465
Query: 137 QEDILNGKENEIKELQQVISQQKQIFRNHMSDFR-IQKQQESYMAQVLDQKHKKASGTRQ 195
++D L +E I +Q ++ +Q+F++ ++ + ++++Q+ Q+ ++ + + +
Sbjct: 2466 EKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEE 2522
Query: 196 ARSHQHPREK 205
AR QH E+
Sbjct: 2523 ARRRQHEAEE 2532
Score = 40.0 bits (92), Expect = 0.001
Identities = 35/180 (19%), Positives = 84/180 (46%), Gaps = 26/180 (14%)
Query: 20 DQLRDVI---ESQEELIHQLRNVMVLQDENFVSKE------EFQAVEKKLVEEKAAHAKT 70
++LR+ I E ++E + Q ++ L+ E + + E QA+++ + EK + +
Sbjct: 2414 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2473
Query: 71 KVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEI 130
+ + +E+ KL+ + ++QL +E+ ++ Q ++ +L+ E
Sbjct: 2474 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQ----------QMEQERQRLVASMEEA 2523
Query: 131 ESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKA 190
+ E+ + K+ E+++L+Q QQ+++ R Q Q+L+++H+ A
Sbjct: 2524 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQ-------LQLLEEQHRAA 2576
Score = 34.7 bits (78), Expect = 0.058
Identities = 36/202 (17%), Positives = 85/202 (42%), Gaps = 29/202 (14%)
Query: 9 KAGSGSVCLALDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHA 68
KA + +V +L+ ++ ++ ++ QLR E +A + E + A
Sbjct: 2020 KAHAFAVQQKEQELQQTLQQEQSVLDQLRG-------------EAEAARRAAEEAEEARV 2066
Query: 69 KTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLA---FEKALSSVKSKVLQESSKKDQLIT 125
+ + A+ +++ E E L + E++ A + A ++ + QE++++ Q
Sbjct: 2067 QAEREAAQSRRQVE----EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA-- 2120
Query: 126 KCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQ 185
E ++Q+ + + + K+ + +QK ++ R+Q ++ + +LD+
Sbjct: 2121 -----EQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDE 2175
Query: 186 --KHKKASGTRQARSHQHPREK 205
+ KA T AR E+
Sbjct: 2176 ELQRLKAEATEAARQRSQVEEE 2197
Score = 33.1 bits (74), Expect = 0.17
Identities = 44/214 (20%), Positives = 93/214 (43%), Gaps = 30/214 (14%)
Query: 1 MATPLGWSKAGSGSVCLALDQLR------DVIESQEEL-IHQLRNVMVLQDENFVSKEEF 53
+A + KA +G L L+ R D + S+E+ + R + +E +E
Sbjct: 1896 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1955
Query: 54 QAVEKKLVEE-------KAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKAL 106
+ V+K L E KAA + + L AK EE + + ++QL+ + A +K L
Sbjct: 1956 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2015
Query: 107 SSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHM 166
+ + +K+Q E++ + +++ +L+ E + ++ + ++
Sbjct: 2016 QAEEKAHAFAVQQKEQ------ELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA----- 2064
Query: 167 SDFRIQKQQESYMA--QVLDQKHKKASGTRQARS 198
R+Q ++E+ + QV + + K S QA++
Sbjct: 2065 ---RVQAEREAAQSRRQVEEAERLKQSAEEQAQA 2095
Score = 32.7 bits (73), Expect = 0.22
Identities = 31/166 (18%), Positives = 78/166 (46%), Gaps = 14/166 (8%)
Query: 30 EELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVE 89
+E + ++ + + + ++ E + +L EK + LL + E++Q
Sbjct: 2393 QEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQ------T 2446
Query: 90 VLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEI-ESHIIKQEDILNGKENEI 148
V +QL +E A +++ S K +LQ +Q K ++ + + K + + ++ +
Sbjct: 2447 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ 2506
Query: 149 KELQQ-----VISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
++++Q V S ++ R H ++ ++++QE Q L+Q+ ++
Sbjct: 2507 QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEE--LQQLEQQRRQ 2550
Score = 31.6 bits (70), Expect = 0.49
Identities = 45/199 (22%), Positives = 85/199 (42%), Gaps = 27/199 (13%)
Query: 27 ESQEELIHQLRNVMVLQDENFVSKE-EFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFAL 85
++QEE R V QDE+ ++ E + + E +AA K + L A EE +LQ
Sbjct: 1459 QAQEEAERLRRQV---QDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1515
Query: 86 GEVEVLSKQLEKEK---LAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQE-DIL 141
E + ++E+ + +A E A S ++++ SK+ K ++E + ++ +
Sbjct: 1516 AERRLRQAEVERARQVQVALETAQRSAEAEL---QSKRASFAEKTAQLERSLQEEHVAVA 1572
Query: 142 NGKENEIKELQQVISQQK------------QIFRNHMSDFRIQKQ---QESYMAQVLDQK 186
+E + QQ ++ Q+ N R+Q + Q+ +AQ +K
Sbjct: 1573 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1632
Query: 187 HKKASGTRQARSHQHPREK 205
K+ R+AR E+
Sbjct: 1633 QKE-EAEREARRRGKAEEQ 1650
Score = 28.9 bits (63), Expect = 3.2
Identities = 29/155 (18%), Positives = 71/155 (45%), Gaps = 13/155 (8%)
Query: 29 QEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEV 88
QEE++ + + Q + +EE Q + + E AK + A E +L+ E+
Sbjct: 1366 QEEVVRREEAAVDAQQQKRSIQEELQQLRQS--SEAEIQAKARQAEAAERSRLRIE-EEI 1422
Query: 89 EVLSKQL---EKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKE 145
V+ QL E+++ E L +++++ + ++K Q + + + Q++ ++
Sbjct: 1423 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQV--QDESQRKRQ 1480
Query: 146 NEIKELQQV-----ISQQKQIFRNHMSDFRIQKQQ 175
E++ +V +++KQ + + R+Q ++
Sbjct: 1481 AEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1515
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 45.1 bits (105), Expect = 4e-05
Identities = 31/130 (23%), Positives = 73/130 (56%), Gaps = 10/130 (7%)
Query: 77 EEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIK 136
+ E+L+ A+ E+E EKEKL E L +KS+ +Q + +++QL+ + ++ +
Sbjct: 2581 DAERLREAIAELE-----REKEKLQQEAKLLQLKSEEMQ-TVQQEQLLQETQALQQSFLS 2634
Query: 137 QEDILNGKENEIKELQQVISQQKQIFRNHMSDFR-IQKQQESYMAQVLDQKHKKASGTRQ 195
++D L +E I +Q ++ +Q+F++ ++ + ++++Q+ Q+ ++ + + +
Sbjct: 2635 EKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEE 2691
Query: 196 ARSHQHPREK 205
AR QH E+
Sbjct: 2692 ARRRQHEAEE 2701
Score = 40.0 bits (92), Expect = 0.001
Identities = 35/180 (19%), Positives = 84/180 (46%), Gaps = 26/180 (14%)
Query: 20 DQLRDVI---ESQEELIHQLRNVMVLQDENFVSKE------EFQAVEKKLVEEKAAHAKT 70
++LR+ I E ++E + Q ++ L+ E + + E QA+++ + EK + +
Sbjct: 2583 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2642
Query: 71 KVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEI 130
+ + +E+ KL+ + ++QL +E+ ++ Q ++ +L+ E
Sbjct: 2643 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQ----------QMEQERQRLVASMEEA 2692
Query: 131 ESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKA 190
+ E+ + K+ E+++L+Q QQ+++ R Q Q+L+++H+ A
Sbjct: 2693 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQ-------LQLLEEQHRAA 2745
Score = 34.7 bits (78), Expect = 0.058
Identities = 36/202 (17%), Positives = 85/202 (42%), Gaps = 29/202 (14%)
Query: 9 KAGSGSVCLALDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHA 68
KA + +V +L+ ++ ++ ++ QLR E +A + E + A
Sbjct: 2189 KAHAFAVQQKEQELQQTLQQEQSVLDQLRG-------------EAEAARRAAEEAEEARV 2235
Query: 69 KTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLA---FEKALSSVKSKVLQESSKKDQLIT 125
+ + A+ +++ E E L + E++ A + A ++ + QE++++ Q
Sbjct: 2236 QAEREAAQSRRQVE----EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA-- 2289
Query: 126 KCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQ 185
E ++Q+ + + + K+ + +QK ++ R+Q ++ + +LD+
Sbjct: 2290 -----EQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDE 2344
Query: 186 --KHKKASGTRQARSHQHPREK 205
+ KA T AR E+
Sbjct: 2345 ELQRLKAEATEAARQRSQVEEE 2366
Score = 33.1 bits (74), Expect = 0.17
Identities = 44/214 (20%), Positives = 93/214 (43%), Gaps = 30/214 (14%)
Query: 1 MATPLGWSKAGSGSVCLALDQLR------DVIESQEEL-IHQLRNVMVLQDENFVSKEEF 53
+A + KA +G L L+ R D + S+E+ + R + +E +E
Sbjct: 2065 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 2124
Query: 54 QAVEKKLVEE-------KAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKAL 106
+ V+K L E KAA + + L AK EE + + ++QL+ + A +K L
Sbjct: 2125 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2184
Query: 107 SSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHM 166
+ + +K+Q E++ + +++ +L+ E + ++ + ++
Sbjct: 2185 QAEEKAHAFAVQQKEQ------ELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA----- 2233
Query: 167 SDFRIQKQQESYMA--QVLDQKHKKASGTRQARS 198
R+Q ++E+ + QV + + K S QA++
Sbjct: 2234 ---RVQAEREAAQSRRQVEEAERLKQSAEEQAQA 2264
Score = 32.7 bits (73), Expect = 0.22
Identities = 31/166 (18%), Positives = 78/166 (46%), Gaps = 14/166 (8%)
Query: 30 EELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVE 89
+E + ++ + + + ++ E + +L EK + LL + E++Q
Sbjct: 2562 QEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQ------T 2615
Query: 90 VLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEI-ESHIIKQEDILNGKENEI 148
V +QL +E A +++ S K +LQ +Q K ++ + + K + + ++ +
Sbjct: 2616 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ 2675
Query: 149 KELQQ-----VISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
++++Q V S ++ R H ++ ++++QE Q L+Q+ ++
Sbjct: 2676 QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEE--LQQLEQQRRQ 2719
Score = 31.6 bits (70), Expect = 0.49
Identities = 45/199 (22%), Positives = 85/199 (42%), Gaps = 27/199 (13%)
Query: 27 ESQEELIHQLRNVMVLQDENFVSKE-EFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFAL 85
++QEE R V QDE+ ++ E + + E +AA K + L A EE +LQ
Sbjct: 1628 QAQEEAERLRRQV---QDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1684
Query: 86 GEVEVLSKQLEKEK---LAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQE-DIL 141
E + ++E+ + +A E A S ++++ SK+ K ++E + ++ +
Sbjct: 1685 AERRLRQAEVERARQVQVALETAQRSAEAEL---QSKRASFAEKTAQLERSLQEEHVAVA 1741
Query: 142 NGKENEIKELQQVISQQK------------QIFRNHMSDFRIQKQ---QESYMAQVLDQK 186
+E + QQ ++ Q+ N R+Q + Q+ +AQ +K
Sbjct: 1742 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1801
Query: 187 HKKASGTRQARSHQHPREK 205
K+ R+AR E+
Sbjct: 1802 QKE-EAEREARRRGKAEEQ 1819
Score = 28.9 bits (63), Expect = 3.2
Identities = 29/155 (18%), Positives = 71/155 (45%), Gaps = 13/155 (8%)
Query: 29 QEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEV 88
QEE++ + + Q + +EE Q + + E AK + A E +L+ E+
Sbjct: 1535 QEEVVRREEAAVDAQQQKRSIQEELQQLRQS--SEAEIQAKARQAEAAERSRLRIE-EEI 1591
Query: 89 EVLSKQL---EKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKE 145
V+ QL E+++ E L +++++ + ++K Q + + + Q++ ++
Sbjct: 1592 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQV--QDESQRKRQ 1649
Query: 146 NEIKELQQV-----ISQQKQIFRNHMSDFRIQKQQ 175
E++ +V +++KQ + + R+Q ++
Sbjct: 1650 AEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1684
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 45.1 bits (105), Expect = 4e-05
Identities = 31/130 (23%), Positives = 73/130 (56%), Gaps = 10/130 (7%)
Query: 77 EEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIK 136
+ E+L+ A+ E+E EKEKL E L +KS+ +Q + +++QL+ + ++ +
Sbjct: 2422 DAERLREAIAELE-----REKEKLQQEAKLLQLKSEEMQ-TVQQEQLLQETQALQQSFLS 2475
Query: 137 QEDILNGKENEIKELQQVISQQKQIFRNHMSDFR-IQKQQESYMAQVLDQKHKKASGTRQ 195
++D L +E I +Q ++ +Q+F++ ++ + ++++Q+ Q+ ++ + + +
Sbjct: 2476 EKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEE 2532
Query: 196 ARSHQHPREK 205
AR QH E+
Sbjct: 2533 ARRRQHEAEE 2542
Score = 40.0 bits (92), Expect = 0.001
Identities = 35/180 (19%), Positives = 84/180 (46%), Gaps = 26/180 (14%)
Query: 20 DQLRDVI---ESQEELIHQLRNVMVLQDENFVSKE------EFQAVEKKLVEEKAAHAKT 70
++LR+ I E ++E + Q ++ L+ E + + E QA+++ + EK + +
Sbjct: 2424 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2483
Query: 71 KVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEI 130
+ + +E+ KL+ + ++QL +E+ ++ Q ++ +L+ E
Sbjct: 2484 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQ----------QMEQERQRLVASMEEA 2533
Query: 131 ESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKA 190
+ E+ + K+ E+++L+Q QQ+++ R Q Q+L+++H+ A
Sbjct: 2534 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQ-------LQLLEEQHRAA 2586
Score = 34.7 bits (78), Expect = 0.058
Identities = 36/202 (17%), Positives = 85/202 (42%), Gaps = 29/202 (14%)
Query: 9 KAGSGSVCLALDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHA 68
KA + +V +L+ ++ ++ ++ QLR E +A + E + A
Sbjct: 2030 KAHAFAVQQKEQELQQTLQQEQSVLDQLRG-------------EAEAARRAAEEAEEARV 2076
Query: 69 KTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLA---FEKALSSVKSKVLQESSKKDQLIT 125
+ + A+ +++ E E L + E++ A + A ++ + QE++++ Q
Sbjct: 2077 QAEREAAQSRRQVE----EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA-- 2130
Query: 126 KCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQ 185
E ++Q+ + + + K+ + +QK ++ R+Q ++ + +LD+
Sbjct: 2131 -----EQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDE 2185
Query: 186 --KHKKASGTRQARSHQHPREK 205
+ KA T AR E+
Sbjct: 2186 ELQRLKAEATEAARQRSQVEEE 2207
Score = 33.1 bits (74), Expect = 0.17
Identities = 44/214 (20%), Positives = 93/214 (43%), Gaps = 30/214 (14%)
Query: 1 MATPLGWSKAGSGSVCLALDQLR------DVIESQEEL-IHQLRNVMVLQDENFVSKEEF 53
+A + KA +G L L+ R D + S+E+ + R + +E +E
Sbjct: 1906 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1965
Query: 54 QAVEKKLVEE-------KAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKAL 106
+ V+K L E KAA + + L AK EE + + ++QL+ + A +K L
Sbjct: 1966 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2025
Query: 107 SSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHM 166
+ + +K+Q E++ + +++ +L+ E + ++ + ++
Sbjct: 2026 QAEEKAHAFAVQQKEQ------ELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA----- 2074
Query: 167 SDFRIQKQQESYMA--QVLDQKHKKASGTRQARS 198
R+Q ++E+ + QV + + K S QA++
Sbjct: 2075 ---RVQAEREAAQSRRQVEEAERLKQSAEEQAQA 2105
Score = 32.7 bits (73), Expect = 0.22
Identities = 31/166 (18%), Positives = 78/166 (46%), Gaps = 14/166 (8%)
Query: 30 EELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVE 89
+E + ++ + + + ++ E + +L EK + LL + E++Q
Sbjct: 2403 QEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQ------T 2456
Query: 90 VLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEI-ESHIIKQEDILNGKENEI 148
V +QL +E A +++ S K +LQ +Q K ++ + + K + + ++ +
Sbjct: 2457 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ 2516
Query: 149 KELQQ-----VISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
++++Q V S ++ R H ++ ++++QE Q L+Q+ ++
Sbjct: 2517 QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEE--LQQLEQQRRQ 2560
Score = 31.6 bits (70), Expect = 0.49
Identities = 45/199 (22%), Positives = 85/199 (42%), Gaps = 27/199 (13%)
Query: 27 ESQEELIHQLRNVMVLQDENFVSKE-EFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFAL 85
++QEE R V QDE+ ++ E + + E +AA K + L A EE +LQ
Sbjct: 1469 QAQEEAERLRRQV---QDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1525
Query: 86 GEVEVLSKQLEKEK---LAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQE-DIL 141
E + ++E+ + +A E A S ++++ SK+ K ++E + ++ +
Sbjct: 1526 AERRLRQAEVERARQVQVALETAQRSAEAEL---QSKRASFAEKTAQLERSLQEEHVAVA 1582
Query: 142 NGKENEIKELQQVISQQK------------QIFRNHMSDFRIQKQ---QESYMAQVLDQK 186
+E + QQ ++ Q+ N R+Q + Q+ +AQ +K
Sbjct: 1583 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1642
Query: 187 HKKASGTRQARSHQHPREK 205
K+ R+AR E+
Sbjct: 1643 QKE-EAEREARRRGKAEEQ 1660
Score = 28.9 bits (63), Expect = 3.2
Identities = 29/155 (18%), Positives = 71/155 (45%), Gaps = 13/155 (8%)
Query: 29 QEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEV 88
QEE++ + + Q + +EE Q + + E AK + A E +L+ E+
Sbjct: 1376 QEEVVRREEAAVDAQQQKRSIQEELQQLRQS--SEAEIQAKARQAEAAERSRLRIE-EEI 1432
Query: 89 EVLSKQL---EKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKE 145
V+ QL E+++ E L +++++ + ++K Q + + + Q++ ++
Sbjct: 1433 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQV--QDESQRKRQ 1490
Query: 146 NEIKELQQV-----ISQQKQIFRNHMSDFRIQKQQ 175
E++ +V +++KQ + + R+Q ++
Sbjct: 1491 AEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1525
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 45.1 bits (105), Expect = 4e-05
Identities = 31/130 (23%), Positives = 73/130 (56%), Gaps = 10/130 (7%)
Query: 77 EEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIK 136
+ E+L+ A+ E+E EKEKL E L +KS+ +Q + +++QL+ + ++ +
Sbjct: 2430 DAERLREAIAELE-----REKEKLQQEAKLLQLKSEEMQ-TVQQEQLLQETQALQQSFLS 2483
Query: 137 QEDILNGKENEIKELQQVISQQKQIFRNHMSDFR-IQKQQESYMAQVLDQKHKKASGTRQ 195
++D L +E I +Q ++ +Q+F++ ++ + ++++Q+ Q+ ++ + + +
Sbjct: 2484 EKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEE 2540
Query: 196 ARSHQHPREK 205
AR QH E+
Sbjct: 2541 ARRRQHEAEE 2550
Score = 40.0 bits (92), Expect = 0.001
Identities = 35/180 (19%), Positives = 84/180 (46%), Gaps = 26/180 (14%)
Query: 20 DQLRDVI---ESQEELIHQLRNVMVLQDENFVSKE------EFQAVEKKLVEEKAAHAKT 70
++LR+ I E ++E + Q ++ L+ E + + E QA+++ + EK + +
Sbjct: 2432 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2491
Query: 71 KVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEI 130
+ + +E+ KL+ + ++QL +E+ ++ Q ++ +L+ E
Sbjct: 2492 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQ----------QMEQERQRLVASMEEA 2541
Query: 131 ESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKA 190
+ E+ + K+ E+++L+Q QQ+++ R Q Q+L+++H+ A
Sbjct: 2542 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQ-------LQLLEEQHRAA 2594
Score = 34.7 bits (78), Expect = 0.058
Identities = 36/202 (17%), Positives = 85/202 (42%), Gaps = 29/202 (14%)
Query: 9 KAGSGSVCLALDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHA 68
KA + +V +L+ ++ ++ ++ QLR E +A + E + A
Sbjct: 2038 KAHAFAVQQKEQELQQTLQQEQSVLDQLRG-------------EAEAARRAAEEAEEARV 2084
Query: 69 KTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLA---FEKALSSVKSKVLQESSKKDQLIT 125
+ + A+ +++ E E L + E++ A + A ++ + QE++++ Q
Sbjct: 2085 QAEREAAQSRRQVE----EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA-- 2138
Query: 126 KCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQ 185
E ++Q+ + + + K+ + +QK ++ R+Q ++ + +LD+
Sbjct: 2139 -----EQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDE 2193
Query: 186 --KHKKASGTRQARSHQHPREK 205
+ KA T AR E+
Sbjct: 2194 ELQRLKAEATEAARQRSQVEEE 2215
Score = 33.1 bits (74), Expect = 0.17
Identities = 44/214 (20%), Positives = 93/214 (43%), Gaps = 30/214 (14%)
Query: 1 MATPLGWSKAGSGSVCLALDQLR------DVIESQEEL-IHQLRNVMVLQDENFVSKEEF 53
+A + KA +G L L+ R D + S+E+ + R + +E +E
Sbjct: 1914 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1973
Query: 54 QAVEKKLVEE-------KAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKAL 106
+ V+K L E KAA + + L AK EE + + ++QL+ + A +K L
Sbjct: 1974 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2033
Query: 107 SSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHM 166
+ + +K+Q E++ + +++ +L+ E + ++ + ++
Sbjct: 2034 QAEEKAHAFAVQQKEQ------ELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA----- 2082
Query: 167 SDFRIQKQQESYMA--QVLDQKHKKASGTRQARS 198
R+Q ++E+ + QV + + K S QA++
Sbjct: 2083 ---RVQAEREAAQSRRQVEEAERLKQSAEEQAQA 2113
Score = 32.7 bits (73), Expect = 0.22
Identities = 31/166 (18%), Positives = 78/166 (46%), Gaps = 14/166 (8%)
Query: 30 EELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVE 89
+E + ++ + + + ++ E + +L EK + LL + E++Q
Sbjct: 2411 QEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQ------T 2464
Query: 90 VLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEI-ESHIIKQEDILNGKENEI 148
V +QL +E A +++ S K +LQ +Q K ++ + + K + + ++ +
Sbjct: 2465 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ 2524
Query: 149 KELQQ-----VISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
++++Q V S ++ R H ++ ++++QE Q L+Q+ ++
Sbjct: 2525 QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEE--LQQLEQQRRQ 2568
Score = 31.6 bits (70), Expect = 0.49
Identities = 45/199 (22%), Positives = 85/199 (42%), Gaps = 27/199 (13%)
Query: 27 ESQEELIHQLRNVMVLQDENFVSKE-EFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFAL 85
++QEE R V QDE+ ++ E + + E +AA K + L A EE +LQ
Sbjct: 1477 QAQEEAERLRRQV---QDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1533
Query: 86 GEVEVLSKQLEKEK---LAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQE-DIL 141
E + ++E+ + +A E A S ++++ SK+ K ++E + ++ +
Sbjct: 1534 AERRLRQAEVERARQVQVALETAQRSAEAEL---QSKRASFAEKTAQLERSLQEEHVAVA 1590
Query: 142 NGKENEIKELQQVISQQK------------QIFRNHMSDFRIQKQ---QESYMAQVLDQK 186
+E + QQ ++ Q+ N R+Q + Q+ +AQ +K
Sbjct: 1591 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1650
Query: 187 HKKASGTRQARSHQHPREK 205
K+ R+AR E+
Sbjct: 1651 QKE-EAEREARRRGKAEEQ 1668
Score = 28.9 bits (63), Expect = 3.2
Identities = 29/155 (18%), Positives = 71/155 (45%), Gaps = 13/155 (8%)
Query: 29 QEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEV 88
QEE++ + + Q + +EE Q + + E AK + A E +L+ E+
Sbjct: 1384 QEEVVRREEAAVDAQQQKRSIQEELQQLRQS--SEAEIQAKARQAEAAERSRLRIE-EEI 1440
Query: 89 EVLSKQL---EKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKE 145
V+ QL E+++ E L +++++ + ++K Q + + + Q++ ++
Sbjct: 1441 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQV--QDESQRKRQ 1498
Query: 146 NEIKELQQV-----ISQQKQIFRNHMSDFRIQKQQ 175
E++ +V +++KQ + + R+Q ++
Sbjct: 1499 AEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1533
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 45.1 bits (105), Expect = 4e-05
Identities = 31/130 (23%), Positives = 73/130 (56%), Gaps = 10/130 (7%)
Query: 77 EEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIK 136
+ E+L+ A+ E+E EKEKL E L +KS+ +Q + +++QL+ + ++ +
Sbjct: 2471 DAERLREAIAELE-----REKEKLQQEAKLLQLKSEEMQ-TVQQEQLLQETQALQQSFLS 2524
Query: 137 QEDILNGKENEIKELQQVISQQKQIFRNHMSDFR-IQKQQESYMAQVLDQKHKKASGTRQ 195
++D L +E I +Q ++ +Q+F++ ++ + ++++Q+ Q+ ++ + + +
Sbjct: 2525 EKDSLLQRERFI---EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEE 2581
Query: 196 ARSHQHPREK 205
AR QH E+
Sbjct: 2582 ARRRQHEAEE 2591
Score = 40.0 bits (92), Expect = 0.001
Identities = 35/180 (19%), Positives = 84/180 (46%), Gaps = 26/180 (14%)
Query: 20 DQLRDVI---ESQEELIHQLRNVMVLQDENFVSKE------EFQAVEKKLVEEKAAHAKT 70
++LR+ I E ++E + Q ++ L+ E + + E QA+++ + EK + +
Sbjct: 2473 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2532
Query: 71 KVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEI 130
+ + +E+ KL+ + ++QL +E+ ++ Q ++ +L+ E
Sbjct: 2533 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQ----------QMEQERQRLVASMEEA 2582
Query: 131 ESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKA 190
+ E+ + K+ E+++L+Q QQ+++ R Q Q+L+++H+ A
Sbjct: 2583 RRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQ-------LQLLEEQHRAA 2635
Score = 34.7 bits (78), Expect = 0.058
Identities = 36/202 (17%), Positives = 85/202 (42%), Gaps = 29/202 (14%)
Query: 9 KAGSGSVCLALDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHA 68
KA + +V +L+ ++ ++ ++ QLR E +A + E + A
Sbjct: 2079 KAHAFAVQQKEQELQQTLQQEQSVLDQLRG-------------EAEAARRAAEEAEEARV 2125
Query: 69 KTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLA---FEKALSSVKSKVLQESSKKDQLIT 125
+ + A+ +++ E E L + E++ A + A ++ + QE++++ Q
Sbjct: 2126 QAEREAAQSRRQVE----EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQA-- 2179
Query: 126 KCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQ 185
E ++Q+ + + + K+ + +QK ++ R+Q ++ + +LD+
Sbjct: 2180 -----EQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDE 2234
Query: 186 --KHKKASGTRQARSHQHPREK 205
+ KA T AR E+
Sbjct: 2235 ELQRLKAEATEAARQRSQVEEE 2256
Score = 33.1 bits (74), Expect = 0.17
Identities = 44/214 (20%), Positives = 93/214 (43%), Gaps = 30/214 (14%)
Query: 1 MATPLGWSKAGSGSVCLALDQLR------DVIESQEEL-IHQLRNVMVLQDENFVSKEEF 53
+A + KA +G L L+ R D + S+E+ + R + +E +E
Sbjct: 1955 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 2014
Query: 54 QAVEKKLVEE-------KAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKAL 106
+ V+K L E KAA + + L AK EE + + ++QL+ + A +K L
Sbjct: 2015 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2074
Query: 107 SSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHM 166
+ + +K+Q E++ + +++ +L+ E + ++ + ++
Sbjct: 2075 QAEEKAHAFAVQQKEQ------ELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEA----- 2123
Query: 167 SDFRIQKQQESYMA--QVLDQKHKKASGTRQARS 198
R+Q ++E+ + QV + + K S QA++
Sbjct: 2124 ---RVQAEREAAQSRRQVEEAERLKQSAEEQAQA 2154
Score = 32.7 bits (73), Expect = 0.22
Identities = 31/166 (18%), Positives = 78/166 (46%), Gaps = 14/166 (8%)
Query: 30 EELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVE 89
+E + ++ + + + ++ E + +L EK + LL + E++Q
Sbjct: 2452 QEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQ------T 2505
Query: 90 VLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEI-ESHIIKQEDILNGKENEI 148
V +QL +E A +++ S K +LQ +Q K ++ + + K + + ++ +
Sbjct: 2506 VQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQ 2565
Query: 149 KELQQ-----VISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
++++Q V S ++ R H ++ ++++QE Q L+Q+ ++
Sbjct: 2566 QQMEQERQRLVASMEEARRRQHEAEEGVRRKQEE--LQQLEQQRRQ 2609
Score = 31.6 bits (70), Expect = 0.49
Identities = 45/199 (22%), Positives = 85/199 (42%), Gaps = 27/199 (13%)
Query: 27 ESQEELIHQLRNVMVLQDENFVSKE-EFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFAL 85
++QEE R V QDE+ ++ E + + E +AA K + L A EE +LQ
Sbjct: 1518 QAQEEAERLRRQV---QDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1574
Query: 86 GEVEVLSKQLEKEK---LAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQE-DIL 141
E + ++E+ + +A E A S ++++ SK+ K ++E + ++ +
Sbjct: 1575 AERRLRQAEVERARQVQVALETAQRSAEAEL---QSKRASFAEKTAQLERSLQEEHVAVA 1631
Query: 142 NGKENEIKELQQVISQQK------------QIFRNHMSDFRIQKQ---QESYMAQVLDQK 186
+E + QQ ++ Q+ N R+Q + Q+ +AQ +K
Sbjct: 1632 QLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK 1691
Query: 187 HKKASGTRQARSHQHPREK 205
K+ R+AR E+
Sbjct: 1692 QKE-EAEREARRRGKAEEQ 1709
Score = 28.9 bits (63), Expect = 3.2
Identities = 29/155 (18%), Positives = 71/155 (45%), Gaps = 13/155 (8%)
Query: 29 QEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEV 88
QEE++ + + Q + +EE Q + + E AK + A E +L+ E+
Sbjct: 1425 QEEVVRREEAAVDAQQQKRSIQEELQQLRQS--SEAEIQAKARQAEAAERSRLRIE-EEI 1481
Query: 89 EVLSKQL---EKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKE 145
V+ QL E+++ E L +++++ + ++K Q + + + Q++ ++
Sbjct: 1482 RVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQV--QDESQRKRQ 1539
Query: 146 NEIKELQQV-----ISQQKQIFRNHMSDFRIQKQQ 175
E++ +V +++KQ + + R+Q ++
Sbjct: 1540 AEVELASRVKAEAEAAREKQRALQALEELRLQAEE 1574
>gi|124249396 coiled-coil domain containing 30 [Homo sapiens]
Length = 783
Score = 44.3 bits (103), Expect = 7e-05
Identities = 45/201 (22%), Positives = 89/201 (44%), Gaps = 38/201 (18%)
Query: 17 LALDQLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAA---------- 66
+ Q + I+ QE L+ QL N DE+ S +E KL +EK A
Sbjct: 433 MTCSQQQSRIQQQEALLKQLENEKRKYDEHVKSNQELSEKLSKLQQEKEALREEYLRLLK 492
Query: 67 ------------HAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKSKVL 114
H + KV L K + +L EVE+ K++ + FE + ++ K+
Sbjct: 493 LLNVHVRNYNEKHHQQKVKLQKVKYRL---TNEVELRDKRINQ----FEDEIGILQHKIE 545
Query: 115 QESSKKDQ-------LITKCNEIESHIIKQEDILNGKENEIKELQ-QVISQQKQIFRNHM 166
+E + +DQ L+ + +++ +I+QE +++ + I +Q +V+ K+ +
Sbjct: 546 KEKAIQDQITAQNDTLLLEKRKLQEQVIEQEQLIHSNKWTISSIQSRVLYMDKENKQLQE 605
Query: 167 SDFRIQKQQESYMAQVLDQKH 187
+ R+ QQ ++ +++ H
Sbjct: 606 NSLRL-TQQIGFLERIIRSIH 625
Score = 34.7 bits (78), Expect = 0.058
Identities = 29/132 (21%), Positives = 62/132 (46%), Gaps = 21/132 (15%)
Query: 52 EFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEVEVLSKQLEKEKLAFEKALSSVKS 111
E Q +E+K+ E AK K +E++K + V+ L +Q+
Sbjct: 378 EKQQLEEKIKEATQNEAKVKQQYQEEQQKRKLLYQNVDELHRQV---------------- 421
Query: 112 KVLQESSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRI 171
+ LQ+ K++ L C++ +S I +QE +L ENE ++ + + +++ ++
Sbjct: 422 RTLQD--KENLLEMTCSQQQSRIQQQEALLKQLENEKRKYDEHVKSNQELSEKLS---KL 476
Query: 172 QKQQESYMAQVL 183
Q+++E+ + L
Sbjct: 477 QQEKEALREEYL 488
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 43.9 bits (102), Expect = 1e-04
Identities = 41/199 (20%), Positives = 94/199 (47%), Gaps = 11/199 (5%)
Query: 16 CLALDQLRDVIES--QEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVL 73
C +++ R +E+ ++E QLR V +D+ +E E++L K A+ +V
Sbjct: 532 CSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERL--RKVLQARERVE 589
Query: 74 LAKEEEKLQFA--LGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEI- 130
KEE+K Q +++ +++ ++E+LA EKA +K ++E + + + +
Sbjct: 590 QMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR 649
Query: 131 ----ESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQK 186
E + +++L K+ E +E + ++ K++ + R Q+++E + ++
Sbjct: 650 WLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERRE 709
Query: 187 HKKASGTRQARSHQHPREK 205
++ RQ + RE+
Sbjct: 710 QERREQERQLAEQERRREQ 728
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 43.5 bits (101), Expect = 1e-04
Identities = 42/192 (21%), Positives = 94/192 (48%), Gaps = 8/192 (4%)
Query: 19 LDQLRDVIESQEELIHQLRNVMVLQDENFVSKEE-FQAVEKKLVEEKAAHAKTKVLLAKE 77
+ + + I QEE I + M Q+E KEE + E+ + E++ + + ++ ++
Sbjct: 316 IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK 375
Query: 78 EEKL---QFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHI 134
EEK+ + + E E ++LE EK+ ++ + + K +E ++Q K E E+ +
Sbjct: 376 EEKMRRQEEMMWEKEEKIRELE-EKMHEQEKIREQEEKRQEEEKIREQ--EKRQEQEAKM 432
Query: 135 IKQEDILNGKENEIKELQQVI-SQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKASGT 193
+QE+ + +E +I+E ++ + Q+++I ++Q++ M + ++ H++
Sbjct: 433 WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIW 492
Query: 194 RQARSHQHPREK 205
RQ EK
Sbjct: 493 RQKEKMHEQEEK 504
Score = 43.1 bits (100), Expect = 2e-04
Identities = 42/180 (23%), Positives = 85/180 (47%), Gaps = 15/180 (8%)
Query: 26 IESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFAL 85
I QEE I + M Q+E +EE E+K+ H + K+ EEEK Q
Sbjct: 519 IREQEEKIREQEEKMWRQEEKIREQEEMWREEEKM------HEQEKIW---EEEKRQ--- 566
Query: 86 GEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKE 145
+ + + +Q EK + EK + K+ ++ K+ + K + E I +QE+ + +E
Sbjct: 567 EQEDKMWRQEEKIREQEEKVWRQ-EEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQE 625
Query: 146 NEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKASGTRQARSHQHPREK 205
+I+E ++ I +Q+++ + + ++ +Q+E Q + ++ + RQ + +K
Sbjct: 626 EKIREQEEKIREQEEMTQE--QEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKK 683
Score = 42.4 bits (98), Expect = 3e-04
Identities = 29/163 (17%), Positives = 81/163 (49%), Gaps = 4/163 (2%)
Query: 27 ESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALG 86
E ++++ Q + +++ + +E+ + E+K E++ K + + ++EEK+Q
Sbjct: 567 EQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQ---- 622
Query: 87 EVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKEN 146
E E ++ E++ E+ + K+ ++ K + K E E + +QE+ + +E
Sbjct: 623 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEK 682
Query: 147 EIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
+I+E ++ I +Q+++ + Q+++ + + ++ +K
Sbjct: 683 KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 725
Score = 39.3 bits (90), Expect = 0.002
Identities = 37/154 (24%), Positives = 75/154 (48%), Gaps = 7/154 (4%)
Query: 29 QEELIHQLRNVMVLQDENFVSKEE-FQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGE 87
+EE + + M Q+E +EE E+K+ E++ + + + K+EEK++ +
Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIR---EQ 617
Query: 88 VEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENE 147
E + +Q EK + EK + QE +Q C + E + +QE+ + +E +
Sbjct: 618 EEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQ-EEKMQEQEETMWRQEEK 676
Query: 148 IKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQ 181
I+E ++ I +Q++ R + +Q+Q+E Q
Sbjct: 677 IREQEKKIREQEEKIRE--QEEMMQEQEEKMWEQ 708
Score = 38.9 bits (89), Expect = 0.003
Identities = 29/153 (18%), Positives = 74/153 (48%), Gaps = 2/153 (1%)
Query: 29 QEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALGEV 88
QEE IH+ + +++ +E+ + E+K+ ++ + + + ++EEK+ ++
Sbjct: 481 QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI 540
Query: 89 EVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENEI 148
+ +E+ E+ + K ++ K + K E E + +QE+ + +E +
Sbjct: 541 REQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKR 600
Query: 149 KELQQVISQQKQIFRNHMSDFRIQKQQESYMAQ 181
+E ++ + +Q++ R + +IQ+Q+E Q
Sbjct: 601 QEQEEKMWKQEEKIRE--QEEKIQEQEEKIREQ 631
Score = 38.1 bits (87), Expect = 0.005
Identities = 40/182 (21%), Positives = 84/182 (46%), Gaps = 20/182 (10%)
Query: 26 IESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFAL 85
I QEE I + M Q+E +E+ + EK+ +E+ + ++EEK+
Sbjct: 439 IREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE---------MWRQEEKIH--- 486
Query: 86 GEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKE 145
E E + +Q EK EK + + KV ++ K + K E E + +QE+ + +E
Sbjct: 487 -EQEEIWRQKEKMHEQEEK-IRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQE 544
Query: 146 NEIKELQQVISQQK--QIFRNHMSDFRIQKQQESYMAQVLDQKHKKASGTRQARSHQHPR 203
+E +++ Q+K + + + ++ +Q+E ++ +Q+ K + R + R
Sbjct: 545 EMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEE----KIREQEEKVWRQEEKIREQEEKR 600
Query: 204 EK 205
++
Sbjct: 601 QE 602
Score = 37.7 bits (86), Expect = 0.007
Identities = 34/173 (19%), Positives = 81/173 (46%), Gaps = 5/173 (2%)
Query: 21 QLRDVIESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEK 80
Q + E +E++ Q + +++ +E+ E+K+ E++ + + + ++EEK
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634
Query: 81 L----QFALGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIK 136
+ + + E + +Q EK EK ++ QE ++Q K E E I +
Sbjct: 635 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQ-EKKIREQEEKIRE 693
Query: 137 QEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKK 189
QE+++ +E ++ E ++ + +Q++ + R Q+++ L Q+ +K
Sbjct: 694 QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 746
Score = 35.4 bits (80), Expect = 0.034
Identities = 29/179 (16%), Positives = 89/179 (49%), Gaps = 33/179 (18%)
Query: 27 ESQEELIHQLRNVMVLQDENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEEEKLQFALG 86
+ +E++ Q + +++ +E+ + E+K+ E++ + + ++ ++EEK++
Sbjct: 297 QQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR---- 352
Query: 87 EVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGKEN 146
+E++ +EK ++ ++++++ E E + +QE+++ KE
Sbjct: 353 ---------RQEEMMWEKE---------EKMRRQEEMMW---EKEEKMRRQEEMMWEKEE 391
Query: 147 EIKELQQVISQQKQIFRNHMSDFRIQKQQESYMAQVLDQKHKKASGTRQARSHQHPREK 205
+I+EL++ + +Q++I R Q+++ ++ +Q+ ++ + R + RE+
Sbjct: 392 KIRELEEKMHEQEKI--------REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 442
Score = 34.7 bits (78), Expect = 0.058
Identities = 36/162 (22%), Positives = 74/162 (45%), Gaps = 18/162 (11%)
Query: 30 EELIHQLRNVMVLQDENFVSKEEFQAVEKKLVE--EKAAHAKTKVLLAKEEEKLQFALGE 87
EEL + + + N ++ EE + KL E + K+++ L +E K + +
Sbjct: 196 EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK 255
Query: 88 VEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCN---------------EIES 132
+ + +QL+ E K L SV +K LQ ++++L + N E E
Sbjct: 256 LLLPQQQLQAEADHLGKELQSVSAK-LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEE 314
Query: 133 HIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFRIQKQ 174
I +QE+ + +E +I+E ++ + +Q+++ R Q++
Sbjct: 315 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE 356
Score = 33.5 bits (75), Expect = 0.13
Identities = 27/133 (20%), Positives = 66/133 (49%), Gaps = 5/133 (3%)
Query: 26 IESQEELIHQLRNVMVLQDENFVSKEEFQAV-EKKLVEEKAAHAKTKVLLAKEEEKLQFA 84
I+ QEE I + + Q+E +EE E+K+ E++ + + + ++EEK++
Sbjct: 621 IQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR-- 678
Query: 85 LGEVEVLSKQLEKEKLAFEKALSSVKSKVLQESSKKDQLITKCNEIESHIIKQEDILNGK 144
E E ++ E++ E+ + + K+ ++ K + K E E + +QE+ + +
Sbjct: 679 --EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 736
Query: 145 ENEIKELQQVISQ 157
E +++ ++ + +
Sbjct: 737 EVRLRQQEEKMQE 749
>gi|4507693 tuberous sclerosis 1 protein isoform 1 [Homo sapiens]
Length = 1164
Score = 43.5 bits (101), Expect = 1e-04
Identities = 48/195 (24%), Positives = 89/195 (45%), Gaps = 39/195 (20%)
Query: 21 QLRDVIESQEELIHQLRNVMV-LQD-ENFVSKEEFQAVEKKLVEEKAAHAKTKVLLAKEE 78
Q+R + +EE +Q + + L+D N +++ +E K K H T++LL++
Sbjct: 778 QIRQLQHDREEFYNQSQELQTKLEDCRNMIAELR---IELKKANNKVCH--TELLLSQVS 832
Query: 79 EKLQ----------------FALGEVEVL------------SKQLEKEKLAFEKALSSVK 110
+KL LGEV L +K++E K A+ K L +
Sbjct: 833 QKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNR 892
Query: 111 SKVLQESSKKDQLITKCNEIESHIIKQEDILNGKENEIKELQQVISQQKQIFRNHMSDFR 170
S VLQ++ + D + E+ESH+ K++ +L ++ K L+ V Q + + S +
Sbjct: 893 SHVLQQTQRLDTSQKRILELESHLAKKDHLLLEQK---KYLEDVKLQARGQLQAAESRYE 949
Query: 171 IQKQ-QESYMAQVLD 184
QK+ + + ++LD
Sbjct: 950 AQKRITQVFELEILD 964
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.125 0.324
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,823,466
Number of Sequences: 37866
Number of extensions: 287728
Number of successful extensions: 3942
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 252
Number of HSP's successfully gapped in prelim test: 537
Number of HSP's that attempted gapping in prelim test: 1950
Number of HSP's gapped (non-prelim): 1949
length of query: 205
length of database: 18,247,518
effective HSP length: 97
effective length of query: 108
effective length of database: 14,574,516
effective search space: 1574047728
effective search space used: 1574047728
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.