Guide to the Human Genome
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Search of human proteins with 210032463

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|210032463 family with sequence similarity 48, member B2
[Homo sapiens]
         (817 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|210032463 family with sequence similarity 48, member B2 [Homo...  1652   0.0  
gi|239752280 PREDICTED: similar to family with sequence similari...  1556   0.0  
gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]        1464   0.0  
gi|98961135 family with sequence similarity 48, member A isoform...   728   0.0  
gi|8923735 family with sequence similarity 48, member A isoform ...   700   0.0  
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    65   3e-10
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       64   4e-10
gi|150170670 piccolo isoform 2 [Homo sapiens]                          63   1e-09
gi|150378539 piccolo isoform 1 [Homo sapiens]                          63   1e-09
gi|7662236 TSC22 domain family, member 2 [Homo sapiens]                62   2e-09
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          62   3e-09
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          62   3e-09
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          62   3e-09
gi|148277037 AP2 associated kinase 1 [Homo sapiens]                    61   5e-09
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    60   1e-08
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    60   1e-08
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ...    60   1e-08
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       59   1e-08
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       59   1e-08
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         58   3e-08
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    57   7e-08
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]                    57   9e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni...    56   2e-07
gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithora...    55   2e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    55   3e-07
gi|7662346 ADNP homeobox 2 [Homo sapiens]                              55   3e-07
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                55   3e-07
gi|119943102 CREB binding protein isoform b [Homo sapiens]             55   3e-07
gi|119943104 CREB binding protein isoform a [Homo sapiens]             55   3e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    54   4e-07

>gi|210032463 family with sequence similarity 48, member B2 [Homo
           sapiens]
          Length = 817

 Score = 1652 bits (4277), Expect = 0.0
 Identities = 817/817 (100%), Positives = 817/817 (100%)

Query: 1   MDRDLEQALDRTENITEIAQQRRPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60
           MDRDLEQALDRTENITEIAQQRRPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS
Sbjct: 1   MDRDLEQALDRTENITEIAQQRRPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60

Query: 61  NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120
           NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE
Sbjct: 61  NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120

Query: 121 LPPALGDVLDKASVNIFHSGCVIVEVRDYRQSSNMQPPGYQSRHILLRPTMQTLAPEVKT 180
           LPPALGDVLDKASVNIFHSGCVIVEVRDYRQSSNMQPPGYQSRHILLRPTMQTLAPEVKT
Sbjct: 121 LPPALGDVLDKASVNIFHSGCVIVEVRDYRQSSNMQPPGYQSRHILLRPTMQTLAPEVKT 180

Query: 181 MTRDGEKWSQEDKFPLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMEQCLQ 240
           MTRDGEKWSQEDKFPLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMEQCLQ
Sbjct: 181 MTRDGEKWSQEDKFPLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMEQCLQ 240

Query: 241 RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNITKAGSCVDTWKGRPCDL 300
           RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNITKAGSCVDTWKGRPCDL
Sbjct: 241 RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNITKAGSCVDTWKGRPCDL 300

Query: 301 AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFRHAWEAGCQAWDTKPNIMQSFND 360
           AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFRHAWEAGCQAWDTKPNIMQSFND
Sbjct: 301 AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFRHAWEAGCQAWDTKPNIMQSFND 360

Query: 361 PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG 420
           PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG
Sbjct: 361 PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG 420

Query: 421 KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF 480
           KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF
Sbjct: 421 KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF 480

Query: 481 PPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVP 540
           PPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVP
Sbjct: 481 PPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVP 540

Query: 541 LIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGS 600
           LIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGS
Sbjct: 541 LIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGS 600

Query: 601 GAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVL 660
           GAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVL
Sbjct: 601 GAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVL 660

Query: 661 TGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGL 720
           TGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGL
Sbjct: 661 TGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGL 720

Query: 721 QPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQP 780
           QPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQP
Sbjct: 721 QPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQP 780

Query: 781 VFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPPAP 817
           VFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPPAP
Sbjct: 781 VFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPPAP 817


>gi|239752280 PREDICTED: similar to family with sequence similarity
           48, member B2 [Homo sapiens]
          Length = 779

 Score = 1556 bits (4029), Expect = 0.0
 Identities = 779/817 (95%), Positives = 779/817 (95%), Gaps = 38/817 (4%)

Query: 1   MDRDLEQALDRTENITEIAQQRRPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60
           MDRDLEQALDRTENITEIAQQRRPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS
Sbjct: 1   MDRDLEQALDRTENITEIAQQRRPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60

Query: 61  NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120
           NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE
Sbjct: 61  NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120

Query: 121 LPPALGDVLDKASVNIFHSGCVIVEVRDYRQSSNMQPPGYQSRHILLRPTMQTLAPEVKT 180
           LPPA                                      RHILLRPTMQTLAPEVKT
Sbjct: 121 LPPA--------------------------------------RHILLRPTMQTLAPEVKT 142

Query: 181 MTRDGEKWSQEDKFPLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMEQCLQ 240
           MTRDGEKWSQEDKFPLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMEQCLQ
Sbjct: 143 MTRDGEKWSQEDKFPLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMEQCLQ 202

Query: 241 RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNITKAGSCVDTWKGRPCDL 300
           RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNITKAGSCVDTWKGRPCDL
Sbjct: 203 RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNITKAGSCVDTWKGRPCDL 262

Query: 301 AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFRHAWEAGCQAWDTKPNIMQSFND 360
           AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFRHAWEAGCQAWDTKPNIMQSFND
Sbjct: 263 AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFRHAWEAGCQAWDTKPNIMQSFND 322

Query: 361 PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG 420
           PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG
Sbjct: 323 PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG 382

Query: 421 KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF 480
           KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF
Sbjct: 383 KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF 442

Query: 481 PPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVP 540
           PPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVP
Sbjct: 443 PPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVP 502

Query: 541 LIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGS 600
           LIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGS
Sbjct: 503 LIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGS 562

Query: 601 GAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVL 660
           GAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVL
Sbjct: 563 GAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVL 622

Query: 661 TGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGL 720
           TGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGL
Sbjct: 623 TGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGL 682

Query: 721 QPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQP 780
           QPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQP
Sbjct: 683 QPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQP 742

Query: 781 VFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPPAP 817
           VFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPPAP
Sbjct: 743 VFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPPAP 779


>gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]
          Length = 887

 Score = 1464 bits (3789), Expect = 0.0
 Identities = 762/887 (85%), Positives = 772/887 (87%), Gaps = 70/887 (7%)

Query: 1   MDRDLEQALDRTENITEIAQQRRPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60
           MDRDLEQALDR ENI EIAQQR PRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS
Sbjct: 1   MDRDLEQALDRAENIIEIAQQRPPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60

Query: 61  NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120
           NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE
Sbjct: 61  NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120

Query: 121 LPPALGDVLDKASVNIFHSGCVIVEVRDYRQSSNMQPPGYQSRHILLRPTMQTLAPEVKT 180
           LPPALGDVLDKASVNIFHSGCVIVEVRDYRQSSNMQPPGYQSRHILLRPTMQTLA +VK 
Sbjct: 121 LPPALGDVLDKASVNIFHSGCVIVEVRDYRQSSNMQPPGYQSRHILLRPTMQTLAHDVKM 180

Query: 181 MTRDGEKWSQEDKFPLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMEQCLQ 240
           MTRDG+KWSQEDK  LESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPM++CLQ
Sbjct: 181 MTRDGQKWSQEDKLQLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMKRCLQ 240

Query: 241 RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNITKAGSCVDTWKGRPCDL 300
           RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNI KAGSCVDTWKGRPCDL
Sbjct: 241 RYSWPSVKPQQEQSDCPPPPELRVSTSGQKEERKVGQPCELNIAKAGSCVDTWKGRPCDL 300

Query: 301 AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFRHAWEAGCQAWDTKPNIMQSFND 360
           AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPF  A EAGCQAWDTKP+IMQSFND
Sbjct: 301 AVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFGFALEAGCQAWDTKPSIMQSFND 360

Query: 361 PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG 420
           PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG
Sbjct: 361 PLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPG 420

Query: 421 KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF 480
           KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF
Sbjct: 421 KMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF 480

Query: 481 PPQQAGSPLKRPF-------------PAAAPAVAAAAPAPAPAPAAAPALAA-------- 519
           PPQQAGSPLKRPF              AAA A AAAAPAPA A AAAPALAA        
Sbjct: 481 PPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPALAA 540

Query: 520 --------------AAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQ 565
                         AA  AAA  AAPSHSQKPSVPLI+ASR  PAA  PT+F+KIAPAIQ
Sbjct: 541 AAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVPLIQASRPCPAAQPPTKFIKIAPAIQ 600

Query: 566 VRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARP 625
           +RTGSTGLKA NVEGPV+GAQ LG SFKPVQAPGSGAPAPAGISGS LQSSGGPLPDARP
Sbjct: 601 LRTGSTGLKAINVEGPVQGAQALGSSFKPVQAPGSGAPAPAGISGSDLQSSGGPLPDARP 660

Query: 626 GAVQASSPAPLQFFLNTPEGLRPLT-LQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHP 684
           GAVQASSPAPLQFFLNTPEGLRPLT LQVPQG AVLTGPQQQSHQLVSLQQLQQPTAAHP
Sbjct: 661 GAVQASSPAPLQFFLNTPEGLRPLTLLQVPQGSAVLTGPQQQSHQLVSLQQLQQPTAAHP 720

Query: 685 PQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQL 744
           PQPGPQGS LGLSTQGQAFPAQQLL VN T A SGLQPQPQ AVLSLLGSAQVPQQGVQL
Sbjct: 721 PQPGPQGSALGLSTQGQAFPAQQLLKVNPTRARSGLQPQPQPAVLSLLGSAQVPQQGVQL 780

Query: 745 PFVL-GQQPQ---PLLLLQPQ------------------------------PQPQQIQLQ 770
           P VL  QQPQ   P L LQPQ                               QPQ IQLQ
Sbjct: 781 PSVLRQQQPQPQPPKLQLQPQWQPKPRQEQPQSQQQQPQHIQLQTQQLRVLQQPQHIQLQ 840

Query: 771 TQPLRVLQQPVFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPPAP 817
           TQ LRVLQQPVFLATGAVQIVQPHPGVQ GSQLV QRK GKPTPPAP
Sbjct: 841 TQQLRVLQQPVFLATGAVQIVQPHPGVQVGSQLVDQRKEGKPTPPAP 887


>gi|98961135 family with sequence similarity 48, member A isoform a
           [Homo sapiens]
          Length = 779

 Score =  728 bits (1878), Expect = 0.0
 Identities = 431/826 (52%), Positives = 518/826 (62%), Gaps = 60/826 (7%)

Query: 1   MDRDLEQALDRTENITEIAQQRRPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60
           M + LE ALDR E + E A+QR P+R+Y     K++ +KLYD+Y+EEC KEPE  ++LR 
Sbjct: 1   MQQALELALDRAEYVIESARQRPPKRKYLSSGRKSVFQKLYDLYIEECEKEPE-VKKLRR 59

Query: 61  NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120
           NVNLLEKLV +E+L CL+VNLYPGN+GYS+ML+ ++GS +ETIRLPYEE  LL+YLDAEE
Sbjct: 60  NVNLLEKLVMQETLSCLVVNLYPGNEGYSLMLRGKNGSDSETIRLPYEEGELLEYLDAEE 119

Query: 121 LPPALGDVLDKASVNIFHSGCVIVEVRDYRQSSNMQPPGYQSRHILLRPTMQTLAPEVKT 180
           LPP L D+L+K+ VNIFH GCVI E+RDYRQSSNM+ PGYQSRHILLRPTMQTL  +V +
Sbjct: 120 LPPILVDLLEKSQVNIFHCGCVIAEIRDYRQSSNMKSPGYQSRHILLRPTMQTLICDVHS 179

Query: 181 MTRDGEKWSQEDKFPLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMEQCLQ 240
           +T D  KW+QEDK  LESQLILATAEPLCLDPS+AV CTANRLLYNKQKMNT PM++C +
Sbjct: 180 ITSDNHKWTQEDKLLLESQLILATAEPLCLDPSIAVTCTANRLLYNKQKMNTRPMKRCFK 239

Query: 241 RYSWPSVKPQQEQSDCPPPPELRVSTSGQK-EERKVGQPCELNITKAGSCVDTWKGRPCD 299
           RYS  S+  QQ+ S CPPPP+LR+    QK +ERK GQ  +L I+KAG+CVD WK  PC+
Sbjct: 240 RYSRSSLNRQQDLSHCPPPPQLRLLDFLQKRKERKAGQHYDLKISKAGNCVDMWKRSPCN 299

Query: 300 LAVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFRHAWEAGCQAWDTKPNIMQSFN 359
           LA+PSEVDVEK AK  +S+ + D Q  VWPA +V+D +    EAG Q   TK  I+QS  
Sbjct: 300 LAIPSEVDVEKYAKVEKSIKSDDSQPTVWPAHDVKDDYVFECEAGTQYQKTKLTILQSLG 359

Query: 360 DPLLCGKIRPRKKARQK-SQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKG 418
           DPL  GKI+P K   +  SQ SP     DDHS     GS+TDA R V+Q QE VQ++ K 
Sbjct: 360 DPLYYGKIQPCKADEESDSQMSPSHSSTDDHSNWFIIGSKTDAERVVNQYQELVQNEAKC 419

Query: 419 PGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGN 478
           P KMSHSSSG AS+SQ+S  K  +Q + V VQSSV GKG KH PP  +LPSSSG  SSGN
Sbjct: 420 PVKMSHSSSGSASLSQVSPGKETDQTETVSVQSSVLGKGVKHRPPPIKLPSSSGNSSSGN 479

Query: 479 SFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPS 538
            F PQQ  S LK P            P P+  P++ P                   +K S
Sbjct: 480 YFTPQQTSSFLKSP-----------TPPPSSKPSSIP-------------------RKSS 509

Query: 539 VPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAP 598
           V L + S   PAA  P    +   A QV   S GL   NV G V GAQ L     P+   
Sbjct: 510 VDLNQVSMLSPAALSPASSSQRTTATQVMANSAGLNFINVVGSVCGAQALMSGSNPMLGC 569

Query: 599 GSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLT-LQVPQGW 657
            +GA  PAGI+ SGL  SGG LP+A P A+QA+S A + F L     LRPL  LQ+P G 
Sbjct: 570 NTGAITPAGINLSGLLPSGGLLPNALPSAMQAASQAGVPFGLKNTSSLRPLNLLQLPGGS 629

Query: 658 AVLTGPQQQSHQLVSL--QQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTG 715
            +    QQQ  QL     QQ QQPT   P QPG QGS  G ++Q QA  AQQ   +NLTG
Sbjct: 630 LIFNTLQQQQQQLSQFTPQQPQQPTTCSPQQPGEQGSEQGSTSQEQALSAQQAAVINLTG 689

Query: 716 AGSGLQPQPQAAVLSLLGSAQ------VPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQL 769
            GS +  Q QAAVLS LGSA+      +PQQ  QL     QQ Q                
Sbjct: 690 VGSFM--QSQAAVLSQLGSAENRPEQSLPQQRFQLSSAFQQQQQ---------------- 731

Query: 770 QTQPLRVLQQPVFLATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPP 815
           Q Q LR LQ  + +A  A Q  Q H     GSQ   + K G PT P
Sbjct: 732 QIQQLRFLQHQMAMAAAAAQTAQLHHHRHTGSQSKSKMKRGTPTTP 777


>gi|8923735 family with sequence similarity 48, member A isoform b
           [Homo sapiens]
          Length = 733

 Score =  700 bits (1806), Expect = 0.0
 Identities = 399/740 (53%), Positives = 485/740 (65%), Gaps = 37/740 (5%)

Query: 1   MDRDLEQALDRTENITEIAQQRRPRRRYSPRAGKTLQEKLYDIYVEECGKEPEDPQELRS 60
           M + LE ALDR E + E A+QR P+R+Y     K++ +KLYD+Y+EEC KEPE  Q+LR 
Sbjct: 1   MQQALELALDRAEYVIESARQRPPKRKYLSSGRKSVFQKLYDLYIEECEKEPEVKQKLRR 60

Query: 61  NVNLLEKLVRRESLPCLLVNLYPGNQGYSVMLQREDGSFAETIRLPYEERALLDYLDAEE 120
           NVNLLEKLV +E+L CL+VNLYPGN+GYS+ML+ ++GS +ETIRLPYEE  LL+YLDAEE
Sbjct: 61  NVNLLEKLVMQETLSCLVVNLYPGNEGYSLMLRGKNGSDSETIRLPYEEGELLEYLDAEE 120

Query: 121 LPPALGDVLDKASVNIFHSGCVIVEVRDYRQSSNMQPPGYQSRHILLRPTMQTLAPEVKT 180
           LPP L D+L+K+ VNIFH GCVI E+RDYRQSSNM+ PGYQSRHILLRPTMQTL  +V +
Sbjct: 121 LPPILVDLLEKSQVNIFHCGCVIAEIRDYRQSSNMKSPGYQSRHILLRPTMQTLICDVHS 180

Query: 181 MTRDGEKWSQEDKFPLESQLILATAEPLCLDPSVAVACTANRLLYNKQKMNTDPMEQCLQ 240
           +T D  KW+QEDK  LESQLILATAEPLCLDPS+AV CTANRLLYNKQKMNT PM++C +
Sbjct: 181 ITSDNHKWTQEDKLLLESQLILATAEPLCLDPSIAVTCTANRLLYNKQKMNTRPMKRCFK 240

Query: 241 RYSWPSVKPQQEQSDCPPPPELRVSTSGQK-EERKVGQPCELNITKAGSCVDTWKGRPCD 299
           RYS  S+  QQ+ S CPPPP+LR+    QK +ERK GQ  +L I+KAG+CVD WK  PC+
Sbjct: 241 RYSRSSLNRQQDLSHCPPPPQLRLLDFLQKRKERKAGQHYDLKISKAGNCVDMWKRSPCN 300

Query: 300 LAVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVEDPFRHAWEAGCQAWDTKPNIMQSFN 359
           LA+PSEVDVEK AK  +S+ + D Q  VWPA +V+D +    EAG Q   TK  I+QS  
Sbjct: 301 LAIPSEVDVEKYAKVEKSIKSDDSQPTVWPAHDVKDDYVFECEAGTQYQKTKLTILQSLG 360

Query: 360 DPLLCGKIRPRKKARQK-SQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKG 418
           DPL  GKI+P K   +  SQ SP     DDHS     GS+TDA R V+Q QE VQ++ K 
Sbjct: 361 DPLYYGKIQPCKADEESDSQMSPSHSSTDDHSNWFIIGSKTDAERVVNQYQELVQNEAKC 420

Query: 419 PGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGN 478
           P KMSHSSSG AS+SQ+S  K  +Q + V VQSSV GKG KH PP  +LPSSSG  SSGN
Sbjct: 421 PVKMSHSSSGSASLSQVSPGKETDQTETVSVQSSVLGKGVKHRPPPIKLPSSSGNSSSGN 480

Query: 479 SFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPS 538
            F PQQ  S LK P            P P+  P++ P                   +K S
Sbjct: 481 YFTPQQTSSFLKSP-----------TPPPSSKPSSIP-------------------RKSS 510

Query: 539 VPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAP 598
           V L + S   PAA  P    +   A QV   S GL   NV G V GAQ L     P+   
Sbjct: 511 VDLNQVSMLSPAALSPASSSQRTTATQVMANSAGLNFINVVGSVCGAQALMSGSNPMLGC 570

Query: 599 GSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLT-LQVPQGW 657
            +GA  PAGI+ SGL  SGG LP+A P A+QA+S A + F L     LRPL  LQ+P G 
Sbjct: 571 NTGAITPAGINLSGLLPSGGLLPNALPSAMQAASQAGVPFGLKNTSSLRPLNLLQLPGGS 630

Query: 658 AVLTGPQQQSHQLVSL--QQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTG 715
            +    QQQ  QL     QQ QQPT   P QPG QGS  G ++Q QA  AQQ   +NLTG
Sbjct: 631 LIFNTLQQQQQQLSQFTPQQPQQPTTCSPQQPGEQGSEQGSTSQEQALSAQQAAVINLTG 690

Query: 716 AGSGLQPQPQAAVLSLLGSA 735
            GS +  Q QAA +++L ++
Sbjct: 691 VGSFM--QSQAAAVAILAAS 708


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 110/417 (26%), Positives = 147/417 (35%), Gaps = 65/417 (15%)

Query: 395 PGSETDAGRAVSQAQES----VQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQ--PDPVW 448
           PG    AG   +Q        + S       +S  ++GPA++  L     P      P +
Sbjct: 184 PGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPF 243

Query: 449 VQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRP--FPAAAPAVAAAAPA 506
           V ++         PP    P++          PP  A + L RP   PA  P  A A P 
Sbjct: 244 VGAAAPPAPAAPSPPAAPAPAAPAAAPP----PPPPAPATLARPPGHPAGPPTAAPAVPP 299

Query: 507 PAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQ- 565
           PA A     A AA A A AAGG A    Q        A      A  P R V+ AP    
Sbjct: 300 PAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQ 359

Query: 566 --VRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDA 623
               +G     A+ V GP     +   +  P  APG+    P G +G+  QS     P A
Sbjct: 360 TLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSL-SRTPTA 418

Query: 624 RPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAH 683
               ++A+          TP  L P   Q PQ    +     Q+ QL             
Sbjct: 419 TTSGIRATL---------TPTVLAPRLPQPPQNPTNI-----QNFQL------------- 451

Query: 684 PPQPGPQGSTLGLSTQGQ--AFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQ- 740
                P G  L  S  GQ    P Q L  +    A +  QPQ   A      ++  P Q 
Sbjct: 452 -----PPGMVLVRSENGQLLMIPQQALAQMQ---AQAHAQPQTTMAPRPATPTSAPPVQI 503

Query: 741 -GVQLPF--VLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQ-----QPVFLATGAVQ 789
             VQ P   ++ +Q  P  +++   Q  Q Q   QP   LQ     QP  +  GA Q
Sbjct: 504 STVQAPGTPIIARQVTPTTIIK---QVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQ 557



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 93/350 (26%), Positives = 119/350 (34%), Gaps = 38/350 (10%)

Query: 425 SSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPP-PRTQLPSSSGKISSGNSFPPQ 483
           + +GPA+ ++ +    PE P     +    G     PP PR  L  +     +    PP 
Sbjct: 71  AGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPP 130

Query: 484 QAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIK 543
           +  +    P PAAA    AA P PAPA  A PA  AA  A A  G  P     P      
Sbjct: 131 EGSAGSCAPVPAAA--AVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPG----- 183

Query: 544 ASRRRPAAGRPTRFVKIAPAIQVRTGSTGL------KATNVEGPVRGAQVLGCSFKPVQA 597
                P  G+P        A Q   GS  L       A  V     G   L    KP  A
Sbjct: 184 -----PGPGKPAG----PGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPA-A 233

Query: 598 PGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGW 657
           PG+    P  +  +   +   P P A P     ++  P       P    P TL  P G 
Sbjct: 234 PGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPP-------PPPPAPATLARPPGH 286

Query: 658 AVLTGPQQQSHQLVSLQQLQQ-PTAAHPPQPGP-QGSTLGLSTQ--GQAFPAQQLLNVNL 713
               GP   +  +      Q   +A   P P P  G   G+S Q    A  A     V  
Sbjct: 287 P--AGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKA 344

Query: 714 TGAGSGLQPQPQAA-VLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQP 762
                 +Q  P AA  L+  G A      V  P + G  P P  +  P P
Sbjct: 345 ESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAP 394



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 102/400 (25%), Positives = 132/400 (33%), Gaps = 76/400 (19%)

Query: 450 QSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAP 509
           Q + S     H  PRT    ++   + GN      +GSP      A A     AAPA   
Sbjct: 32  QLAASAAHHHHLAPRTPEVRAAAAGALGNHVV---SGSP------AGAAGAGPAAPAEG- 81

Query: 510 APAAAPALAAAAVAAAAGGAAPSHSQKPSV--PLIKASRRRPAAGRPTRFVKIAPAIQVR 567
           AP AAP    A   A  GG  P     PS   PL+ A    PAA       K+ P  +  
Sbjct: 82  APGAAPEPPPAG-RARPGGGGPQRPGPPSPRRPLVPAGPAPPAA-------KLRPPPEGS 133

Query: 568 TGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGIS---------GSGLQSSGG 618
            GS          PV  A  +    +P  A  +    PA ++         G G     G
Sbjct: 134 AGSC--------APVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPG 185

Query: 619 PLPDARPGAVQ-------------ASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQ 665
           P   A PGA Q             A++PA +    N P  L PL      G  + T P  
Sbjct: 186 PGKPAGPGAAQTLNGSAALLNSHHAAAPA-VSLVNNGPAALLPLPKPAAPGTVIQTPPFV 244

Query: 666 QSHQLVSLQQLQQPT-------AAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGS 718
            +    +      P        AA PP P P  +TL       A P           A  
Sbjct: 245 GAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPT---------AAP 295

Query: 719 GLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQP-LLLLQPQPQPQQIQLQTQPLRVL 777
            + P   A      G+A  P      P  +  QP P      P P  +       P RV+
Sbjct: 296 AVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVK----AESPKRVV 351

Query: 778 QQPVFLATGAVQIVQPHPGVQAGSQLVG-QRKGGKPTPPA 816
           Q        A  +    P   A S ++G   +G  P+P A
Sbjct: 352 QA---APPAAQTLAASGPASTAASMVIGPTMQGALPSPAA 388



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 92/382 (24%), Positives = 140/382 (36%), Gaps = 86/382 (22%)

Query: 441 PEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAV 500
           P  P P   Q+  + +  + PP    + S +G++       PQQA + ++    A A A 
Sbjct: 434 PRLPQPP--QNPTNIQNFQLPPGMVLVRSENGQLL----MIPQQALAQMQ----AQAHAQ 483

Query: 501 AAAAPAPAPA-PAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVK 559
                AP PA P +AP +  + V A   G      Q     +IK   +     +P+  ++
Sbjct: 484 PQTTMAPRPATPTSAPPVQISTVQAP--GTPIIARQVTPTTIIKQVSQAQTTVQPSATLQ 541

Query: 560 IAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAG------------ 607
            +P +Q +    G   T   G     Q  G   + V  PG+   + A             
Sbjct: 542 RSPGVQPQLVLGGAAQTASLGTATAVQT-GTPQRTV--PGATTTSSAATETMENVKKCKN 598

Query: 608 -------ISGSGLQSSGGP------LPDARPGAVQA------------SSPAP--LQFFL 640
                  ++ SG QS+         + +   G ++A            SSP P  + F  
Sbjct: 599 FLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLK 658

Query: 641 NTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQG 700
            +   LR LT   P   A +   QQQ                 PP P  Q +T  L+   
Sbjct: 659 RSLPALRQLT---PDSAAFIQQSQQQ-----------------PPPPTSQATT-ALTAVV 697

Query: 701 QAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVP--QQGVQLPFVLGQQPQPLLLL 758
            +   Q+          S LQP     VLSL    QV   +QG   P V+ Q P+P  L+
Sbjct: 698 LSSSVQRTAGKTAATVTSALQPP----VLSLTQPTQVGVGKQGQPTPLVIQQPPKPGALI 753

Query: 759 QPQPQPQQIQLQTQPLRVLQQP 780
               +P Q+ L   P+  L+QP
Sbjct: 754 ----RPPQVTLTQTPMVALRQP 771


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 126/451 (27%), Positives = 161/451 (35%), Gaps = 81/451 (17%)

Query: 392  CLRPGSETDAGRAVSQAQESV---QSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVW 448
            C  P SE   G  + Q+  S+   Q     PG    S   PA    L        PDP  
Sbjct: 652  CSPPVSE---GPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQ----HFPDPAM 704

Query: 449  VQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPA-- 506
              + V       PPP T +P+  G+ +     PP Q   PL +P P   P V A  P   
Sbjct: 705  SFAPVL------PPPSTPMPTGPGQPA-----PPGQQPPPLAQPTP--LPQVLAPQPVVP 751

Query: 507  --PAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRF--VKIAP 562
              P P P   P LA A+   A     P   Q P  PL      +P A  P +   + + P
Sbjct: 752  LQPVP-PHLPPYLAPASQVGAPAQLKP--LQMPQAPL------QPLAQVPPQMPPIPVVP 802

Query: 563  AIQVRTGSTGLK------ATNVEGPVRGAQVLGCSFKP-VQAPGSGAPAPAGISGSGLQS 615
             I    G  GL        T    PV   Q     F P V  P   AP P       LQ+
Sbjct: 803  PITPLAGIDGLPPALPDLPTATVPPVPPPQY----FSPAVILPSLAAPLPPASPALPLQA 858

Query: 616  SGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQ 675
               P P   P A+   +  P     N P  + PL    P G A L+      H  V+   
Sbjct: 859  VKLPHPPGAPLAMPCRTIVP-----NAPATI-PLLAVAPPGVAALS-----IHSAVAQLP 907

Query: 676  LQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLL-GS 734
             Q    A  PQ  P        T     P   + N+  T     L PQP      +L   
Sbjct: 908  GQPVYPAAFPQMAP--------TDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQ 959

Query: 735  AQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQI-------QLQTQPLR--VLQQPVFLAT 785
              +P Q V LP    + PQP+L  QP   PQ +        ++ +PL+  + +Q    AT
Sbjct: 960  PTLPPQPV-LPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAAT 1018

Query: 786  GAVQIVQPHPGVQAGSQLVGQRKGGKPTPPA 816
               QI+  HP   A    V  +    P PPA
Sbjct: 1019 PGSQILLGHPAPYAVD--VAAQVPTVPVPPA 1047



 Score = 37.7 bits (86), Expect = 0.043
 Identities = 59/250 (23%), Positives = 94/250 (37%), Gaps = 27/250 (10%)

Query: 409  QESVQSKVKGP---GKMSHSSSGPASVSQLSSWKTPEQPD---PVWVQSSVSGKGEKHPP 462
            +ES QS+   P     + H+      +  ++    PE P+   P+ + S      +   P
Sbjct: 1289 EESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSAP 1348

Query: 463  PRTQLPS-------SSGKISS--GNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAA 513
             + QL S       +S ++ S  G S PP    +PL    P++ P  A      APA + 
Sbjct: 1349 YKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLA---PSSPPVTALPQDGAAPATST 1405

Query: 514  APALAAAAVAAAAGGAAP---SHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGS 570
             P  A+   + A G   P   +   + S PL + +   P A +P   V +AP       +
Sbjct: 1406 MPEPASGTASQAGGPGTPQGLTSELETSQPLAE-THEAPLAVQPL-VVGLAPCTPAPEAA 1463

Query: 571  TGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPA---PAGISGSGLQSSGGPLPDARPGA 627
            +   A+    P+               P  G PA   PA +    L +S  P P   P  
Sbjct: 1464 STRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGP-T 1522

Query: 628  VQASSPAPLQ 637
            V    P+ L+
Sbjct: 1523 VPPQPPSALE 1532



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 99/451 (21%), Positives = 137/451 (30%), Gaps = 88/451 (19%)

Query: 381  PWQPFPDDHSACLRPGSETDAG---RAVSQAQESVQSKVKGPGKM------------SHS 425
            P QP P      L P S+  A    + +   Q  +Q   + P +M            +  
Sbjct: 751  PLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGI 810

Query: 426  SSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQA 485
               P ++  L +   P  P P +              P   LPS +  +   +   P QA
Sbjct: 811  DGLPPALPDLPTATVPPVPPPQYFS------------PAVILPSLAAPLPPASPALPLQA 858

Query: 486  GSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKAS 545
               +K P P  AP           APA  P LA A    AA     + +Q P  P+    
Sbjct: 859  ---VKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVY--- 912

Query: 546  RRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAP 605
                    P  F ++A                                P   P S     
Sbjct: 913  --------PAAFPQMA--------------------------------PTDVPPSPHHTV 932

Query: 606  AGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQ 665
              +  +  Q +  P P   P  V    P      +  P+  RP    +P     +  PQ 
Sbjct: 933  QNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPP--QPMLPPQP 990

Query: 666  QSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQ 725
                  +L    +P   H P+     +T G S      PA   ++V    A     P P 
Sbjct: 991  VLPPQPALPVRPEPLQPHLPEQAAPAATPG-SQILLGHPAPYAVDV---AAQVPTVPVPP 1046

Query: 726  AAVLSLLGSAQVPQQGVQLPFVLGQQPQ-PLLLLQPQPQPQQIQLQTQPLRVLQQPVFLA 784
            AAVLS       P   V LP      PQ P  L       Q +  QT  L     P    
Sbjct: 1047 AAVLS------PPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPL-- 1098

Query: 785  TGAVQIVQPHPGVQAGSQLVGQRKGGKPTPP 815
             G   I  P P VQ   + V + +  +  PP
Sbjct: 1099 PGGPGIASPCPTVQLTVEPVQEEQASQDKPP 1129



 Score = 31.6 bits (70), Expect = 3.1
 Identities = 53/252 (21%), Positives = 87/252 (34%), Gaps = 17/252 (6%)

Query: 383  QPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGK-----MSHSSSGPASVSQLSS 437
            QP  +        G+  + G + S   ES    + G  +      S S   P+    + +
Sbjct: 1620 QPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPA 1679

Query: 438  WKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAA 497
            +  P + +P       +G+    PPP + + +  G+ S   +   +  GSP KRP     
Sbjct: 1680 FVRPARVEPTDRDGGEAGESSAEPPP-SDMGTVGGQASHPQTLGARALGSPRKRP----- 1733

Query: 498  PAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRF 557
                    +PA        ++       A   +  +S  P V L +A    P      R 
Sbjct: 1734 --EQQDVSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAP-SSPDVKLAVRR 1790

Query: 558  VKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSG---APAPAGISGSGLQ 614
             + A +I+V  G      +  EGP     V   +  PV    +G     A A +      
Sbjct: 1791 AQTASSIEVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRA 1850

Query: 615  SSGGPLPDARPG 626
             S GP   +R G
Sbjct: 1851 GSLGPETPSRVG 1862


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 104/399 (26%), Positives = 148/399 (37%), Gaps = 40/399 (10%)

Query: 368 RPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQ-ESVQSKVKGPGKMSHSS 426
           +P    +   Q+ P +P P        P  +    +++S  Q E ++S+  G GK     
Sbjct: 202 KPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGK---PI 258

Query: 427 SGPASVSQLSSWKTPEQPDPVWVQSSVSG--KGEKHPPPRTQLPSSSG---KISSGNSFP 481
            GP    Q    K P Q D    Q+  +   +GE   P    LPS S    +  +    P
Sbjct: 259 QGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKP---SLPSPSKPPIQQPTPGKPP 315

Query: 482 PQQAGSPLKRPFPAAAPAVAAAAPAPAPA------PAAAPALAAAAVAAAAGGAAP---- 531
            QQ G    +P PA  PA  +    P         P   P       A   G A P    
Sbjct: 316 AQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQ 375

Query: 532 SHSQKPSV--PLIKASRRRPAAGR-PTRFVKIA--PAIQVRTGSTGLKATNVEGPVRGAQ 586
           + S+KPS   P  KA  + P  G+ P +    A  P  QV T     +   ++ P   A+
Sbjct: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSP---AK 432

Query: 587 VLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQA-SSPAPLQFFLNTPEG 645
             G +  PVQ PG G   PA  +G G  S+    P   P  +   + P P Q     P  
Sbjct: 433 APGPTKTPVQQPGPGK-IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP 491

Query: 646 LRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPP--QPGPQGSTLGLSTQGQAF 703
            +P + + P      T P  Q          QQP +  PP  QPG    +    +  +  
Sbjct: 492 QQPGSAKPPSQQPGSTKPPPQQPGPAKPSP-QQPGSTKPPSQQPGSAKPSAQQPSPAKPS 550

Query: 704 PAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGV 742
             Q    V+ TG+G  LQP   +       + Q P QG+
Sbjct: 551 AQQSTKPVSQTGSGKPLQPPTVSP-----SAKQPPSQGL 584



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 108/461 (23%), Positives = 151/461 (32%), Gaps = 79/461 (17%)

Query: 418 GPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSG--KGEKHPPPRTQLPSSSGKIS 475
           G G  SH++      + LS     E+     V S   G  KG   PP   + PS   K  
Sbjct: 28  GAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSV-PPAAAESPSMHRKQE 86

Query: 476 SGNSFPPQQAGSPLKRPFPAAAPAVAAAAP-----APAPAPAAAPALAAAAVAAAAGGAA 530
             +S PP+Q+G P   P   A P ++ +       +    P  +P+  +   + +     
Sbjct: 87  LDSSHPPKQSGRP-PDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLK 145

Query: 531 PSHSQKPSVPLIKASRRRPAAG------RPTRFVKIAPAIQVRTGSTGLKATNVEGPVRG 584
             H        +       A         P   +  + A Q  T          +G   G
Sbjct: 146 EEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEG 205

Query: 585 AQVLGCSFKP--VQAPGSGAPAPAGISGSGLQSSGGP--LPDARPGAVQASSPA---PLQ 637
                   KP   Q P    P   G     LQ  G P  +   +P  +++  P    P+Q
Sbjct: 206 I------IKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQ 259

Query: 638 FFLNTP-----------EGLRPLTLQ--VPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHP 684
               TP           +  RP T Q  + +G +V     + S    S   +QQPT   P
Sbjct: 260 GPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESV-----KPSLPSPSKPPIQQPTPGKP 314

Query: 685 P--QPGPQGSTLG-----LSTQGQAFP-AQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQ 736
           P  QPG + S  G         G   P AQQ   V       G    P       LG A+
Sbjct: 315 PAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQP----LGPAK 370

Query: 737 VPQQGVQLPFVLGQQPQPLLLLQP---------QPQPQQIQLQT--QPLRVLQQPVFLAT 785
            P Q         +QP P  L QP         QP P +   Q    P  + QQP   + 
Sbjct: 371 PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSP 430

Query: 786 G------AVQIVQPHPG----VQAGSQLVGQRKGGKPTPPA 816
                     + QP PG     QAG      ++ G   PP+
Sbjct: 431 AKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS 471



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 50/192 (26%), Positives = 73/192 (38%), Gaps = 23/192 (11%)

Query: 366  KIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHS 425
            K  P+K   + S K   +P P        PG    AG+ V   Q+S +     P + S  
Sbjct: 852  KEEPKKAQTKMSPKPDAKPMPKGSPT--PPGPRPTAGQTVPTPQQSPK-----PQEQSRR 904

Query: 426  SSGPASVSQLSSWKTPEQPDPVWVQSSVSGK----GEKHPPPRTQLPSSSGK----ISSG 477
             S       L S     +  P   Q +V+GK    G       + L S++G+      SG
Sbjct: 905  FS-----LNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSG 959

Query: 478  NSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKP 537
               P +QA +P + P     P     AP   PAPA +  +     A AA    P   Q P
Sbjct: 960  PGAPMKQAPAPSQPPTSQGPPKSTGQAP---PAPAKSIPVKKETKAPAAEKLEPKAEQAP 1016

Query: 538  SVPLIKASRRRP 549
            +V   +  ++ P
Sbjct: 1017 TVKRTETEKKPP 1028



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 79/353 (22%), Positives = 127/353 (35%), Gaps = 56/353 (15%)

Query: 228 QKMNTDPMEQCLQRYSWPSVKPQQEQSDC------------PPPPELRVSTSGQKEERKV 275
           Q   TD  +  LQR    + +PQ +Q+D             P  P ++  T G+   ++ 
Sbjct: 263 QTPQTDHAKLPLQR---DASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQP 319

Query: 276 GQPCELNITKAGSCVDTWKGRPCDLAVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVED 335
           G                 K +P     P++          Q  T   P  P    +    
Sbjct: 320 GHE---------------KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ 364

Query: 336 PFRHAWEAGCQAWDTKPNIMQSFNDPLLCGKIRPRKKARQKSQ-KSPWQPFPDDHSACLR 394
           P   A     Q    KP+  Q     L       +  A+Q    K P Q          +
Sbjct: 365 PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424

Query: 395 PGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVS 454
           PG ++ A +A    +  VQ    GPGK+    +GP   S        +Q  P    S + 
Sbjct: 425 PGLQSPA-KAPGPTKTPVQQP--GPGKIPAQQAGPGKTSA-------QQTGPTKPPSQLP 474

Query: 455 GKGEKHPPPRTQLPSSSGKISSGNSFPP-QQAGS---PLKRPFPA-AAPAVAAAAPAPAP 509
           G  +  PPP+   P+       G++ PP QQ GS   P ++P PA  +P    +   P+ 
Sbjct: 475 GPAK--PPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532

Query: 510 APAAA------PALAAAAVAAAAGGAAPSHSQKPSVP--LIKASRRRPAAGRP 554
            P +A      P+ A  +   +    + + S KP  P  +  ++++ P+ G P
Sbjct: 533 QPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP 585



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 74/363 (20%), Positives = 123/363 (33%), Gaps = 61/363 (16%)

Query: 392 CLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQS 451
           CL    +   G  ++    S Q K+K     + S+    S S     +T  + D    Q 
Sbjct: 637 CLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA---VSKSSPQPQQTSPKKDAAPKQD 693

Query: 452 SVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAA-------AA 504
                  K PPP  + P+  G  S+    PP+     L +P P   P+V +       A 
Sbjct: 694 LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE--ADSLSKPAPPKEPSVPSEQDKAPVAD 751

Query: 505 PAPAPAPAAAPALAAAAVAAAA------GGAAPSHSQKPSVPLIKASRRRPAAGRPTRFV 558
             P       P     + ++A            S +++ + P +K    +P+   P    
Sbjct: 752 DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGE 811

Query: 559 KIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGA--PAPAGISGSGLQSS 616
           K++P            +  +  P   ++++       ++ G     P          Q+ 
Sbjct: 812 KVSP----------FDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTK 861

Query: 617 GGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQL-VSLQQ 675
             P PDA+P  +   SP        TP G RP   Q          PQ+QS +  ++L  
Sbjct: 862 MSPKPDAKP--MPKGSP--------TPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGS 911

Query: 676 LQQPTAAHP--PQPGPQGSTLG------------LSTQGQAFPAQQLLNVNLTGAGSGLQ 721
           +     + P  PQ    G   G            +ST GQ  P  Q      +G G+ ++
Sbjct: 912 ITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQ------SGPGAPMK 965

Query: 722 PQP 724
             P
Sbjct: 966 QAP 968



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 57/267 (21%), Positives = 88/267 (32%), Gaps = 35/267 (13%)

Query: 372 KARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPAS 431
           K +Q     P        SA  +P  +  + +  SQA+E     +K       S S P +
Sbjct: 753 KPKQPKMVKPTTDLVSSSSATTKP--DIPSSKVQSQAEEKTTPPLK-TDSAKPSQSFPPT 809

Query: 432 VSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKR 491
             ++S + +   P P      +S     HP P ++               P++A + +  
Sbjct: 810 GEKVSPFDSKAIPRPASDSKIIS-----HPGPSSESKGQKQVDPVQKKEEPKKAQTKMS- 863

Query: 492 PFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAA 551
           P P A P    +   P P P A             G   P+  Q P  P  ++ R     
Sbjct: 864 PKPDAKPMPKGSPTPPGPRPTA-------------GQTVPTPQQSPK-PQEQSRRFSLNL 909

Query: 552 GRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGS 611
           G  T   K  P     T +  L          GA +   +   +    +G P P   SG 
Sbjct: 910 GSITDAPKSQPTTPQETVTGKLFGF-------GASIFSQASNLIST--AGQPGPHSQSGP 960

Query: 612 GLQSSGGPLPDARP---GAVQASSPAP 635
           G      P P   P   G  +++  AP
Sbjct: 961 GAPMKQAPAPSQPPTSQGPPKSTGQAP 987


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 104/399 (26%), Positives = 148/399 (37%), Gaps = 40/399 (10%)

Query: 368 RPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQ-ESVQSKVKGPGKMSHSS 426
           +P    +   Q+ P +P P        P  +    +++S  Q E ++S+  G GK     
Sbjct: 202 KPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGK---PI 258

Query: 427 SGPASVSQLSSWKTPEQPDPVWVQSSVSG--KGEKHPPPRTQLPSSSG---KISSGNSFP 481
            GP    Q    K P Q D    Q+  +   +GE   P    LPS S    +  +    P
Sbjct: 259 QGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKP---SLPSPSKPPIQQPTPGKPP 315

Query: 482 PQQAGSPLKRPFPAAAPAVAAAAPAPAPA------PAAAPALAAAAVAAAAGGAAP---- 531
            QQ G    +P PA  PA  +    P         P   P       A   G A P    
Sbjct: 316 AQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQ 375

Query: 532 SHSQKPSV--PLIKASRRRPAAGR-PTRFVKIA--PAIQVRTGSTGLKATNVEGPVRGAQ 586
           + S+KPS   P  KA  + P  G+ P +    A  P  QV T     +   ++ P   A+
Sbjct: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSP---AK 432

Query: 587 VLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQA-SSPAPLQFFLNTPEG 645
             G +  PVQ PG G   PA  +G G  S+    P   P  +   + P P Q     P  
Sbjct: 433 APGPTKTPVQQPGPGK-IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP 491

Query: 646 LRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPP--QPGPQGSTLGLSTQGQAF 703
            +P + + P      T P  Q          QQP +  PP  QPG    +    +  +  
Sbjct: 492 QQPGSAKPPSQQPGSTKPPPQQPGPAKPSP-QQPGSTKPPSQQPGSAKPSAQQPSPAKPS 550

Query: 704 PAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGV 742
             Q    V+ TG+G  LQP   +       + Q P QG+
Sbjct: 551 AQQSTKPVSQTGSGKPLQPPTVSP-----SAKQPPSQGL 584



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 108/461 (23%), Positives = 151/461 (32%), Gaps = 79/461 (17%)

Query: 418 GPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSG--KGEKHPPPRTQLPSSSGKIS 475
           G G  SH++      + LS     E+     V S   G  KG   PP   + PS   K  
Sbjct: 28  GAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSV-PPAAAESPSMHRKQE 86

Query: 476 SGNSFPPQQAGSPLKRPFPAAAPAVAAAAP-----APAPAPAAAPALAAAAVAAAAGGAA 530
             +S PP+Q+G P   P   A P ++ +       +    P  +P+  +   + +     
Sbjct: 87  LDSSHPPKQSGRP-PDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLK 145

Query: 531 PSHSQKPSVPLIKASRRRPAAG------RPTRFVKIAPAIQVRTGSTGLKATNVEGPVRG 584
             H        +       A         P   +  + A Q  T          +G   G
Sbjct: 146 EEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEG 205

Query: 585 AQVLGCSFKP--VQAPGSGAPAPAGISGSGLQSSGGP--LPDARPGAVQASSPA---PLQ 637
                   KP   Q P    P   G     LQ  G P  +   +P  +++  P    P+Q
Sbjct: 206 I------IKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQ 259

Query: 638 FFLNTP-----------EGLRPLTLQ--VPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHP 684
               TP           +  RP T Q  + +G +V     + S    S   +QQPT   P
Sbjct: 260 GPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESV-----KPSLPSPSKPPIQQPTPGKP 314

Query: 685 P--QPGPQGSTLG-----LSTQGQAFP-AQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQ 736
           P  QPG + S  G         G   P AQQ   V       G    P       LG A+
Sbjct: 315 PAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQP----LGPAK 370

Query: 737 VPQQGVQLPFVLGQQPQPLLLLQP---------QPQPQQIQLQT--QPLRVLQQPVFLAT 785
            P Q         +QP P  L QP         QP P +   Q    P  + QQP   + 
Sbjct: 371 PPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSP 430

Query: 786 G------AVQIVQPHPG----VQAGSQLVGQRKGGKPTPPA 816
                     + QP PG     QAG      ++ G   PP+
Sbjct: 431 AKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS 471



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 50/192 (26%), Positives = 73/192 (38%), Gaps = 23/192 (11%)

Query: 366  KIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHS 425
            K  P+K   + S K   +P P        PG    AG+ V   Q+S +     P + S  
Sbjct: 852  KEEPKKAQTKMSPKPDAKPMPKGSPT--PPGPRPTAGQTVPTPQQSPK-----PQEQSRR 904

Query: 426  SSGPASVSQLSSWKTPEQPDPVWVQSSVSGK----GEKHPPPRTQLPSSSGK----ISSG 477
             S       L S     +  P   Q +V+GK    G       + L S++G+      SG
Sbjct: 905  FS-----LNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSG 959

Query: 478  NSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKP 537
               P +QA +P + P     P     AP   PAPA +  +     A AA    P   Q P
Sbjct: 960  PGAPMKQAPAPSQPPTSQGPPKSTGQAP---PAPAKSIPVKKETKAPAAEKLEPKAEQAP 1016

Query: 538  SVPLIKASRRRP 549
            +V   +  ++ P
Sbjct: 1017 TVKRTETEKKPP 1028



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 79/353 (22%), Positives = 127/353 (35%), Gaps = 56/353 (15%)

Query: 228 QKMNTDPMEQCLQRYSWPSVKPQQEQSDC------------PPPPELRVSTSGQKEERKV 275
           Q   TD  +  LQR    + +PQ +Q+D             P  P ++  T G+   ++ 
Sbjct: 263 QTPQTDHAKLPLQR---DASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQP 319

Query: 276 GQPCELNITKAGSCVDTWKGRPCDLAVPSEVDVEKLAKGYQSVTAADPQLPVWPAQEVED 335
           G                 K +P     P++          Q  T   P  P    +    
Sbjct: 320 GHE---------------KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ 364

Query: 336 PFRHAWEAGCQAWDTKPNIMQSFNDPLLCGKIRPRKKARQKSQ-KSPWQPFPDDHSACLR 394
           P   A     Q    KP+  Q     L       +  A+Q    K P Q          +
Sbjct: 365 PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424

Query: 395 PGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVS 454
           PG ++ A +A    +  VQ    GPGK+    +GP   S        +Q  P    S + 
Sbjct: 425 PGLQSPA-KAPGPTKTPVQQP--GPGKIPAQQAGPGKTSA-------QQTGPTKPPSQLP 474

Query: 455 GKGEKHPPPRTQLPSSSGKISSGNSFPP-QQAGS---PLKRPFPA-AAPAVAAAAPAPAP 509
           G  +  PPP+   P+       G++ PP QQ GS   P ++P PA  +P    +   P+ 
Sbjct: 475 GPAK--PPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532

Query: 510 APAAA------PALAAAAVAAAAGGAAPSHSQKPSVP--LIKASRRRPAAGRP 554
            P +A      P+ A  +   +    + + S KP  P  +  ++++ P+ G P
Sbjct: 533 QPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP 585



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 74/363 (20%), Positives = 123/363 (33%), Gaps = 61/363 (16%)

Query: 392 CLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQS 451
           CL    +   G  ++    S Q K+K     + S+    S S     +T  + D    Q 
Sbjct: 637 CLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA---VSKSSPQPQQTSPKKDAAPKQD 693

Query: 452 SVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAA-------AA 504
                  K PPP  + P+  G  S+    PP+     L +P P   P+V +       A 
Sbjct: 694 LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE--ADSLSKPAPPKEPSVPSEQDKAPVAD 751

Query: 505 PAPAPAPAAAPALAAAAVAAAA------GGAAPSHSQKPSVPLIKASRRRPAAGRPTRFV 558
             P       P     + ++A            S +++ + P +K    +P+   P    
Sbjct: 752 DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGE 811

Query: 559 KIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGA--PAPAGISGSGLQSS 616
           K++P            +  +  P   ++++       ++ G     P          Q+ 
Sbjct: 812 KVSP----------FDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTK 861

Query: 617 GGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQL-VSLQQ 675
             P PDA+P  +   SP        TP G RP   Q          PQ+QS +  ++L  
Sbjct: 862 MSPKPDAKP--MPKGSP--------TPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGS 911

Query: 676 LQQPTAAHP--PQPGPQGSTLG------------LSTQGQAFPAQQLLNVNLTGAGSGLQ 721
           +     + P  PQ    G   G            +ST GQ  P  Q      +G G+ ++
Sbjct: 912 ITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQ------SGPGAPMK 965

Query: 722 PQP 724
             P
Sbjct: 966 QAP 968



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 57/267 (21%), Positives = 88/267 (32%), Gaps = 35/267 (13%)

Query: 372 KARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPAS 431
           K +Q     P        SA  +P  +  + +  SQA+E     +K       S S P +
Sbjct: 753 KPKQPKMVKPTTDLVSSSSATTKP--DIPSSKVQSQAEEKTTPPLK-TDSAKPSQSFPPT 809

Query: 432 VSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKR 491
             ++S + +   P P      +S     HP P ++               P++A + +  
Sbjct: 810 GEKVSPFDSKAIPRPASDSKIIS-----HPGPSSESKGQKQVDPVQKKEEPKKAQTKMS- 863

Query: 492 PFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAA 551
           P P A P    +   P P P A             G   P+  Q P  P  ++ R     
Sbjct: 864 PKPDAKPMPKGSPTPPGPRPTA-------------GQTVPTPQQSPK-PQEQSRRFSLNL 909

Query: 552 GRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGS 611
           G  T   K  P     T +  L          GA +   +   +    +G P P   SG 
Sbjct: 910 GSITDAPKSQPTTPQETVTGKLFGF-------GASIFSQASNLIST--AGQPGPHSQSGP 960

Query: 612 GLQSSGGPLPDARP---GAVQASSPAP 635
           G      P P   P   G  +++  AP
Sbjct: 961 GAPMKQAPAPSQPPTSQGPPKSTGQAP 987


>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
          Length = 780

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 116/429 (27%), Positives = 153/429 (35%), Gaps = 88/429 (20%)

Query: 389 HSACLRPGSETDAGR-AVSQAQESVQSKVKGP-GKMSHSSSGPASVSQLSSWKTPEQPDP 446
           HS+     +E D+G  A   +   V + ++G  G  S + S   +VSQL   +   QP P
Sbjct: 204 HSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTP 263

Query: 447 VWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAA----PAVAA 502
              QS   G+ +  PPP        G ++        Q+ +PL  PFP AA    P +AA
Sbjct: 264 AQPQSFSVGQPQPPPPP------VGGAVA--------QSSAPLP-PFPGAATGPQPMMAA 308

Query: 503 AAPA-PAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSV-PLIKASRRRPAAGRPTRFVKI 560
           A P+ P  A      L    V  A     P+ S  P   P + A    PAA +P +F   
Sbjct: 309 AQPSQPQGAGPGGQTLPPTNVTLAQ----PAMSLPPQPGPAVGA----PAAQQPQQFAYP 360

Query: 561 APAIQVR-------TGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGL 613
            P I          +G +     +V G    +     S     +P + A  P G +G   
Sbjct: 361 QPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVG-TGQNA 419

Query: 614 QSSGGPLPDA----------RPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAV--LT 661
            S G  L  A          R G  Q    AP Q     P G+ P T+    G  V    
Sbjct: 420 SSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQ-----PTGVPPATV----GGVVQPCL 470

Query: 662 GPQQQSHQLVSLQQLQQPTAAHPPQPG-----------PQGSTLGLSTQGQAFPAQQLLN 710
           GP              QP +  PPQ G           P     G+     A PA  + +
Sbjct: 471 GPAGAG----------QPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPS 520

Query: 711 VNLTGAGSGLQPQPQAAVLSLLGSAQVPQ-----QGVQLPFVLGQQPQPLLLLQPQPQPQ 765
           V+ T       P P A    L     V +     Q V LP   G    P  L  PQ    
Sbjct: 521 VSTTSVTMPNVPAPLAQSQQLSSHTPVSRSSSIIQHVGLPLAPGTHSAPTSL--PQSDLS 578

Query: 766 QIQLQTQPL 774
           Q Q QTQPL
Sbjct: 579 QFQTQTQPL 587



 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 109/467 (23%), Positives = 159/467 (34%), Gaps = 67/467 (14%)

Query: 386 PDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPD 445
           P    +C +  S T A  A S  +++         +    SS    VS+ + +   E  +
Sbjct: 5   PAKKKSCFQITSVTTAQVATSITEDTESLDDPDESRTEDVSSEIFDVSRATDYGPEEVCE 64

Query: 446 PVWVQSSVSGKGEKHPPPRTQLPSS--SGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAA 503
               + +++  G+   P  T  P+    G++++  + P    G    R    A  +  AA
Sbjct: 65  RSSSEETLNNVGDAETPG-TVSPNLLLDGQLAAAAAAPANGGGVVSARSVSGALASTLAA 123

Query: 504 APAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIA-- 561
           A   APAP A      A  +A    AAPS          +  +    +G P R  +    
Sbjct: 124 AATSAPAPGAPGGPQLAGSSAGPVTAAPSQPPTTCSSRFRVIKLDHGSGEPYRRGRWTCM 183

Query: 562 --------PAIQVRTGSTGLKATNVEGPVR---GAQVLGCSFKPVQAPGSGAPAPAGISG 610
                    ++  R+G     ++  +       G    G S   V A   GA  P   + 
Sbjct: 184 EYYERDSDSSVLTRSGDCIRHSSTFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTD 243

Query: 611 SGLQ----------------------SSGGPLPDARP-GAVQASSPAPLQFFLNTPEGLR 647
           S L                       S G P P   P G   A S APL  F     G +
Sbjct: 244 SSLTAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQ 303

Query: 648 PLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQ-GSTLGLSTQGQAFPAQ 706
           P+            GP  Q+    ++  L QP  + PPQPGP  G+      Q  A+P  
Sbjct: 304 PMMAAAQPSQPQGAGPGGQTLPPTNV-TLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQP 362

Query: 707 Q-----LLNVNLTGAG-------SGLQPQPQAAVLSLLGSAQVPQQGVQLPF-------- 746
           Q     LL V  +G         +GLQP P  A  S  G+A  P     LP         
Sbjct: 363 QIPPGHLLPVQPSGQSEYLQQHVAGLQP-PSPAQPSSTGAAASPATAATLPVGTGQNASS 421

Query: 747 ----VLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQPVFLATGAVQ 789
               ++G   QP   + P+  P Q   Q  P +    P     G VQ
Sbjct: 422 VGAQLMGASSQPSEAMAPRTGPAQ-GGQVAPCQPTGVPPATVGGVVQ 467


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 116/460 (25%), Positives = 151/460 (32%), Gaps = 76/460 (16%)

Query: 371 KKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQ------SKVKGPGKMSH 424
           KK+ +K ++    P   +     +  S+T+     S  +   Q      S  +G G+ S 
Sbjct: 76  KKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSD 135

Query: 425 S-------SSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKH----PPPRTQLPSSSGK 473
           S       SS P  + Q +   +P  P P   +S      ++      PP  Q P+  G 
Sbjct: 136 SRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT--GV 193

Query: 474 ISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSH 533
             + +S PP     P   P P+A       +P  + AP    A  A         A   H
Sbjct: 194 TPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH 253

Query: 534 SQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFK 593
            Q+P  P             P       P +Q  TGS G             Q    S  
Sbjct: 254 PQRPPSP------------HPPPHPSPHPPLQPLTGSAG-------------QPSAPSHA 288

Query: 594 PVQAPGSGAPAPAGI-SGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLT-L 651
                G G P P  + +G  LQ  G P P   P    +   APL     +P    P T L
Sbjct: 289 QPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQA-SQGQAPLG---TSPAAAYPHTSL 344

Query: 652 QVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQ------PGPQGSTLGLSTQGQAFPA 705
           Q+P   + L   Q    Q +    L  P    PP       P PQ         G   P+
Sbjct: 345 QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG---PS 401

Query: 706 QQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQ 765
              +N N       L P P    LS L S   P      P  L  Q QPL     QP P 
Sbjct: 402 PFSMNAN-------LPPPPALKPLSSL-STHHPPSAHPPPLQLMPQSQPLPSSPAQP-PG 452

Query: 766 QIQLQTQPLRVLQQPVFLATGAVQIV-QP----HPGVQAG 800
             Q Q  P      P    TG  Q+  QP    HP V  G
Sbjct: 453 LTQSQNLPPPPASHP---PTGLHQVAPQPPFAQHPFVPGG 489


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 116/460 (25%), Positives = 151/460 (32%), Gaps = 76/460 (16%)

Query: 371  KKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQ------SKVKGPGKMSH 424
            KK+ +K ++    P   +     +  S+T+     S  +   Q      S  +G G+ S 
Sbjct: 630  KKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSD 689

Query: 425  S-------SSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKH----PPPRTQLPSSSGK 473
            S       SS P  + Q +   +P  P P   +S      ++      PP  Q P+  G 
Sbjct: 690  SRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT--GV 747

Query: 474  ISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSH 533
              + +S PP     P   P P+A       +P  + AP    A  A         A   H
Sbjct: 748  TPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH 807

Query: 534  SQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFK 593
             Q+P  P             P       P +Q  TGS G             Q    S  
Sbjct: 808  PQRPPSP------------HPPPHPSPHPPLQPLTGSAG-------------QPSAPSHA 842

Query: 594  PVQAPGSGAPAPAGI-SGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLT-L 651
                 G G P P  + +G  LQ  G P P   P    +   APL     +P    P T L
Sbjct: 843  QPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQA-SQGQAPLG---TSPAAAYPHTSL 898

Query: 652  QVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQ------PGPQGSTLGLSTQGQAFPA 705
            Q+P   + L   Q    Q +    L  P    PP       P PQ         G   P+
Sbjct: 899  QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG---PS 955

Query: 706  QQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQ 765
               +N N       L P P    LS L S   P      P  L  Q QPL     QP P 
Sbjct: 956  PFSMNAN-------LPPPPALKPLSSL-STHHPPSAHPPPLQLMPQSQPLPSSPAQP-PG 1006

Query: 766  QIQLQTQPLRVLQQPVFLATGAVQIV-QP----HPGVQAG 800
              Q Q  P      P    TG  Q+  QP    HP V  G
Sbjct: 1007 LTQSQNLPPPPASHP---PTGLHQVAPQPPFAQHPFVPGG 1043


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 116/460 (25%), Positives = 151/460 (32%), Gaps = 76/460 (16%)

Query: 371  KKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQ------SKVKGPGKMSH 424
            KK+ +K ++    P   +     +  S+T+     S  +   Q      S  +G G+ S 
Sbjct: 630  KKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSD 689

Query: 425  S-------SSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKH----PPPRTQLPSSSGK 473
            S       SS P  + Q +   +P  P P   +S      ++      PP  Q P+  G 
Sbjct: 690  SRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT--GV 747

Query: 474  ISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSH 533
              + +S PP     P   P P+A       +P  + AP    A  A         A   H
Sbjct: 748  TPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH 807

Query: 534  SQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFK 593
             Q+P  P             P       P +Q  TGS G             Q    S  
Sbjct: 808  PQRPPSP------------HPPPHPSPHPPLQPLTGSAG-------------QPSAPSHA 842

Query: 594  PVQAPGSGAPAPAGI-SGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLT-L 651
                 G G P P  + +G  LQ  G P P   P    +   APL     +P    P T L
Sbjct: 843  QPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQA-SQGQAPLG---TSPAAAYPHTSL 898

Query: 652  QVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQ------PGPQGSTLGLSTQGQAFPA 705
            Q+P   + L   Q    Q +    L  P    PP       P PQ         G   P+
Sbjct: 899  QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG---PS 955

Query: 706  QQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQ 765
               +N N       L P P    LS L S   P      P  L  Q QPL     QP P 
Sbjct: 956  PFSMNAN-------LPPPPALKPLSSL-STHHPPSAHPPPLQLMPQSQPLPSSPAQP-PG 1006

Query: 766  QIQLQTQPLRVLQQPVFLATGAVQIV-QP----HPGVQAG 800
              Q Q  P      P    TG  Q+  QP    HP V  G
Sbjct: 1007 LTQSQNLPPPPASHP---PTGLHQVAPQPPFAQHPFVPGG 1043


>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
          Length = 961

 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 90/325 (27%), Positives = 115/325 (35%), Gaps = 39/325 (12%)

Query: 506 APAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQ 565
           +P PA    P  A+ A A      A      P+     A R+RP AG+      I P   
Sbjct: 327 SPIPAKLPEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILP--- 383

Query: 566 VRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARP 625
           ++   T  K   V+ P + A   G S +P        P P       L  +    P A P
Sbjct: 384 IQPALTPRKRATVQPPPQAA---GSSNQPGLLASVPQPKPQAPPSQPLPQTQAKQPQAPP 440

Query: 626 GAVQASS------PAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQ---L 676
              Q  S      PA  Q    TP+  + L L+  Q        QQQ       QQ    
Sbjct: 441 TPQQTPSTQAQGLPAQAQA---TPQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQT 497

Query: 677 QQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQ 736
           QQ  A HP    P  +   + +QG +   QQL+           Q Q Q  + + L   Q
Sbjct: 498 QQFQAVHPATQQPAIAQFPVVSQGGS--QQQLMQNFYQQQQQQQQQQQQQQLATALHQQQ 555

Query: 737 VPQQGVQLP----FVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQPVFLATGAVQIVQ 792
           +  Q   L        GQQPQP     PQP P Q      P+R  QQP    T       
Sbjct: 556 LMTQQAALQQKPTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVR--QQPKVQTT------- 606

Query: 793 PHPGVQAGSQLVGQRKGGKPTPPAP 817
           P P VQ      GQ+ G    P +P
Sbjct: 607 PPPAVQ------GQKVGSLTPPSSP 625



 Score = 31.2 bits (69), Expect = 4.1
 Identities = 31/127 (24%), Positives = 47/127 (37%), Gaps = 17/127 (13%)

Query: 474 ISSGNSFPPQQAGSPLKRPFPAAAPAVAAAA-PAPAPAPAAAPALAAAAVAAAAGGAAP- 531
           +++G    PQ A +P  +P PA  PA+ A     P       PA+    V +    ++P 
Sbjct: 569 MAAGQQPQPQPAAAP--QPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQKVGSLTPPSSPK 626

Query: 532 -------------SHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNV 578
                        +HS    VP  K+++   AA       K   A    +GS      NV
Sbjct: 627 TQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAAAEASLNKSKSATTTPSGSPRTSQQNV 686

Query: 579 EGPVRGA 585
             P  G+
Sbjct: 687 YNPSEGS 693



 Score = 30.0 bits (66), Expect = 9.0
 Identities = 30/153 (19%), Positives = 56/153 (36%), Gaps = 6/153 (3%)

Query: 384 PFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQ 443
           P P+  ++ + P    +  +A   A +  Q K +    +  + +  A   +  + +T   
Sbjct: 320 PIPNVQNSPI-PAKLPEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPN 378

Query: 444 PDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAA 503
           P  + +Q +++ +      P  Q   SS +     S P  +  +P  +P P        A
Sbjct: 379 PGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQTQAKQPQA 438

Query: 504 APAPAPAPAAAPALAAAAVAAAAGGAAPSHSQK 536
            P P   P+       A    A   A P H Q+
Sbjct: 439 PPTPQQTPS-----TQAQGLPAQAQATPQHQQQ 466


>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 67/244 (27%), Positives = 92/244 (37%), Gaps = 40/244 (16%)

Query: 416 VKGPGKMS----HSSSGPA---SVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLP 468
           ++GPG++      S S PA      Q+   +    P PV V  +VS      PP      
Sbjct: 60  LRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVS------PPLEPAAE 113

Query: 469 SSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGG 528
           S  G   +    P     +P   P P     V A APAPAPAP AAP  A  AVA  A  
Sbjct: 114 SLDGLEEAPEQLPSVPVPAPASTPPPVP---VLAPAPAPAPAPVAAPVAAPVAVAVLAPA 170

Query: 529 AAPSHSQKPSVPLIKASRRRPA-----AGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVR 583
            AP+ +  P+   + A    PA     A  P      AP      G+   +    + P+ 
Sbjct: 171 PAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGAN--QGQRGQEPLA 228

Query: 584 GAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPL------------PDARPGAVQAS 631
                G S +P     +   A A  +G+ ++   GPL            P+   G V A 
Sbjct: 229 DQLHSGISGRP-----AAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAP 283

Query: 632 SPAP 635
            P+P
Sbjct: 284 CPSP 287


>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 67/244 (27%), Positives = 92/244 (37%), Gaps = 40/244 (16%)

Query: 416 VKGPGKMS----HSSSGPA---SVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLP 468
           ++GPG++      S S PA      Q+   +    P PV V  +VS      PP      
Sbjct: 60  LRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVS------PPLEPAAE 113

Query: 469 SSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGG 528
           S  G   +    P     +P   P P     V A APAPAPAP AAP  A  AVA  A  
Sbjct: 114 SLDGLEEAPEQLPSVPVPAPASTPPPVP---VLAPAPAPAPAPVAAPVAAPVAVAVLAPA 170

Query: 529 AAPSHSQKPSVPLIKASRRRPA-----AGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVR 583
            AP+ +  P+   + A    PA     A  P      AP      G+   +    + P+ 
Sbjct: 171 PAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGAN--QGQRGQEPLA 228

Query: 584 GAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPL------------PDARPGAVQAS 631
                G S +P     +   A A  +G+ ++   GPL            P+   G V A 
Sbjct: 229 DQLHSGISGRP-----AAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAP 283

Query: 632 SPAP 635
            P+P
Sbjct: 284 CPSP 287


>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
           sapiens]
          Length = 316

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 67/244 (27%), Positives = 92/244 (37%), Gaps = 40/244 (16%)

Query: 416 VKGPGKMS----HSSSGPA---SVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLP 468
           ++GPG++      S S PA      Q+   +    P PV V  +VS      PP      
Sbjct: 71  LRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVS------PPLEPAAE 124

Query: 469 SSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGG 528
           S  G   +    P     +P   P P     V A APAPAPAP AAP  A  AVA  A  
Sbjct: 125 SLDGLEEAPEQLPSVPVPAPASTPPPVP---VLAPAPAPAPAPVAAPVAAPVAVAVLAPA 181

Query: 529 AAPSHSQKPSVPLIKASRRRPA-----AGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVR 583
            AP+ +  P+   + A    PA     A  P      AP      G+   +    + P+ 
Sbjct: 182 PAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGAN--QGQRGQEPLA 239

Query: 584 GAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPL------------PDARPGAVQAS 631
                G S +P     +   A A  +G+ ++   GPL            P+   G V A 
Sbjct: 240 DQLHSGISGRP-----AAGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSGDVPAP 294

Query: 632 SPAP 635
            P+P
Sbjct: 295 CPSP 298


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 107/443 (24%), Positives = 150/443 (33%), Gaps = 75/443 (16%)

Query: 404  AVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPP 463
            A S +QES+ ++ +G G   HS   PA             P P       SG G+  PP 
Sbjct: 611  ARSPSQESIGARSRGSG---HSQEQPA-------------PQP-------SG-GDPSPPQ 646

Query: 464  RTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVA 523
               LP  + +     S  P Q   P    +P  +P    ++PAP P P A  A +     
Sbjct: 647  ERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSP----SSPAPGPPPGAPWAFS----Y 698

Query: 524  AAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGST-GLKATNVEGPV 582
             A   A P    +P       SR  P  G            +   GST G  AT    P 
Sbjct: 699  LAGPPATPPDPPRPKRRSHSLSRPGPTEG------DAEGEAEGPVGSTLGSYATLTRRPG 752

Query: 583  RGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASS--PAPLQFFL 640
            R A ++  S      P  G P     +    +    P P  R  +V   S  P PL    
Sbjct: 753  RSA-LVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESP 811

Query: 641  NTPEGL---RPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLS 697
               EG    R  TL  P G +   GP   +      ++ +      PP  G  G  L  +
Sbjct: 812  GPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFA 871

Query: 698  TQG---------------QAFPAQQLLNVNLTGAGSGLQPQP--------QAAVLSLLGS 734
             +G               +  P    L+ NLT + + ++ +P        Q A+L+   +
Sbjct: 872  EEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDT-VKRRPKCREREPLQTALLAFGVA 930

Query: 735  AQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQPVFLATGAVQIVQPH 794
            +  P     LP     +  P   L PQP+P  +  Q  P  +   P          V P 
Sbjct: 931  SATPGPAAPLPSPTPGESPPASSL-PQPEPSSLPAQGVPTPLAPSPAMQPP-----VPPC 984

Query: 795  PGVQAGSQLVGQRKGGKPTPPAP 817
            PG    S    +  G    P AP
Sbjct: 985  PGPGLESSAASRWNGETEPPAAP 1007


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 107/443 (24%), Positives = 150/443 (33%), Gaps = 75/443 (16%)

Query: 404  AVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPP 463
            A S +QES+ ++ +G G   HS   PA             P P       SG G+  PP 
Sbjct: 693  ARSPSQESIGARSRGSG---HSQEQPA-------------PQP-------SG-GDPSPPQ 728

Query: 464  RTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVA 523
               LP  + +     S  P Q   P    +P  +P    ++PAP P P A  A +     
Sbjct: 729  ERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSP----SSPAPGPPPGAPWAFS----Y 780

Query: 524  AAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGST-GLKATNVEGPV 582
             A   A P    +P       SR  P  G            +   GST G  AT    P 
Sbjct: 781  LAGPPATPPDPPRPKRRSHSLSRPGPTEG------DAEGEAEGPVGSTLGSYATLTRRPG 834

Query: 583  RGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASS--PAPLQFFL 640
            R A ++  S      P  G P     +    +    P P  R  +V   S  P PL    
Sbjct: 835  RSA-LVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESP 893

Query: 641  NTPEGL---RPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLS 697
               EG    R  TL  P G +   GP   +      ++ +      PP  G  G  L  +
Sbjct: 894  GPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFA 953

Query: 698  TQG---------------QAFPAQQLLNVNLTGAGSGLQPQP--------QAAVLSLLGS 734
             +G               +  P    L+ NLT + + ++ +P        Q A+L+   +
Sbjct: 954  EEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDT-VKRRPKCREREPLQTALLAFGVA 1012

Query: 735  AQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQPVFLATGAVQIVQPH 794
            +  P     LP     +  P   L PQP+P  +  Q  P  +   P          V P 
Sbjct: 1013 SATPGPAAPLPSPTPGESPPASSL-PQPEPSSLPAQGVPTPLAPSPAMQPP-----VPPC 1066

Query: 795  PGVQAGSQLVGQRKGGKPTPPAP 817
            PG    S    +  G    P AP
Sbjct: 1067 PGPGLESSAASRWNGETEPPAAP 1089


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 95/409 (23%), Positives = 141/409 (34%), Gaps = 53/409 (12%)

Query: 420  GKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNS 479
            G   H  S PA V+ + +      P PV V  S +       P  T  P+      + N 
Sbjct: 1245 GGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSST-------PSTTPAPTGLSLPLAANQ 1297

Query: 480  FPPQQAGSP-------LKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPS 532
             PP    +         + P     P V   APAP P  +  PA     V        P 
Sbjct: 1298 VPPTMVNNTGVVKIVVRQAPRDGLTP-VPPLAPAPRPPSSGLPA-----VLNPRPTLTPG 1351

Query: 533  HSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVL-GCS 591
                P++   +A    P   RP   +  +P+ +V   + G     +  P+     L G +
Sbjct: 1352 RLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPA 1411

Query: 592  FKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTL 651
              P+  P S +P  + +S +        LP + P  + A + APL   ++ P     LT+
Sbjct: 1412 SSPMPIPNS-SPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAP-----LTV 1465

Query: 652  QVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGS-------TLGLSTQGQAFP 704
                G A+LT        +V       P A  PP   P G+       TLGL+T      
Sbjct: 1466 SA-SGPALLTSVTPPLAPVV-------PAAPGPPSLAPSGASPSASALTLGLATAPSLSS 1517

Query: 705  AQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPL---LLLQPQ 761
            +Q   +  L    S   P   + V        VP   +  PF     P P    LL    
Sbjct: 1518 SQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPAS 1577

Query: 762  PQPQQIQLQTQPLRVLQQPVFLATGA-----VQIVQPHPG---VQAGSQ 802
               Q +     P+   Q  +   + A     + ++ P PG   V A SQ
Sbjct: 1578 SASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQ 1626



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 96/419 (22%), Positives = 132/419 (31%), Gaps = 61/419 (14%)

Query: 393  LRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSS 452
            L PG         ++A     + V+   K+ HS S   S S   +        P+ V SS
Sbjct: 1348 LTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTIS-SPLHVPSS 1406

Query: 453  VSGKGEKHPPPRTQLP-----SSSGKISSGNSFP-------PQQAGSPLKRPF------- 493
            + G      P     P     SS+  +   +S P       P  A +PL  P        
Sbjct: 1407 LPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVS 1466

Query: 494  -----------PAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLI 542
                       P  AP V AA   P+ AP+ A   A+A     A   + S SQ P  PL+
Sbjct: 1467 ASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLL 1526

Query: 543  KASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPV-----------RGAQVLGCS 591
             A       G  +        + V   +      +   P              +Q L   
Sbjct: 1527 LAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATP 1586

Query: 592  FKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTL 651
              P+ AP +   AP+            P P A P    + +P P+    +TP        
Sbjct: 1587 LAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASAS 1646

Query: 652  QVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGS-TLGLS-----TQGQAFPA 705
             VP    VL           S  Q   P     P P P  + TL L+     T G + P+
Sbjct: 1647 PVPAPTPVLA---------PSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPS 1697

Query: 706  QQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQP 764
            Q L      G G+   P P   +     S+ VP     L    G    P   L   P P
Sbjct: 1698 QTL----SLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAP 1752



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 102/406 (25%), Positives = 144/406 (35%), Gaps = 61/406 (15%)

Query: 418  GPGKMSHSSSGP---------ASVSQLSSWKTPEQPDPVWVQSS-VSGKGEKHPPPRTQL 467
            GP  ++ S + P         A+   LSS +TP  P  +   SS V G      P  + +
Sbjct: 1489 GPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPV 1548

Query: 468  PSSSGKISSGNSFP----PQQAGSPLKRPFPAAAPAVAAA-APAPAP-----APAAAPAL 517
               +  ++S   FP    P  A + L  P  +A+ A+A   AP  AP     AP+ AP L
Sbjct: 1549 LVPASALAS--PFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPL 1606

Query: 518  AAAAVAAAAGGAAP--SHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKA 575
            A   V A + GAAP  + SQ P   +  +S    +    +      P +   +  T L A
Sbjct: 1607 APLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPA 1666

Query: 576  TNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASS--P 633
                     A     +  P  AP  G  +P+     G  +  GP P        ASS  P
Sbjct: 1667 PVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVP 1726

Query: 634  APLQFFLNTP------------EGLRPLTLQVPQGWA----VLTGPQQQSHQLVSLQQLQ 677
             P Q     P                PL    P G A    +   P   S  L++   +Q
Sbjct: 1727 TPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQ 1786

Query: 678  QPTAAHPPQP--GPQGS-TLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGS 734
              T +  P P  GP  + TL L+      PA Q  ++                V+S  G+
Sbjct: 1787 TLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSL----------------VVSASGA 1830

Query: 735  AQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQP 780
            A +P   V    V   +P  L L    P P          R  +QP
Sbjct: 1831 APLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPRRQP 1876



 Score = 38.1 bits (87), Expect = 0.033
 Identities = 38/143 (26%), Positives = 55/143 (38%), Gaps = 17/143 (11%)

Query: 401  AGRAVSQAQESV----QSKVKGPGKMSHSSSGPASVSQLSSWKT--PEQPDPVWVQSSVS 454
            A + + QA+E V    Q + +GPG    SS G    +   S K   PE+P     +    
Sbjct: 2342 ARKDLDQAKEEVFRLPQEEEEGPGAGDESSCGTGGGTHRRSKKAKAPERPGTRVSERLRG 2401

Query: 455  GKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAA 514
             + E      T  P  S   +   + PP+ + +  + P PA         P P P PA+A
Sbjct: 2402 ARAETQGANHT--PVISAHQTRSTTTPPRCSPARERVPRPA---------PRPRPTPASA 2450

Query: 515  PALAAAAVAAAAGGAAPSHSQKP 537
            PA   A V        P  +  P
Sbjct: 2451 PAAIPALVPVPVSAPVPISAPNP 2473



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 79/374 (21%), Positives = 125/374 (33%), Gaps = 76/374 (20%)

Query: 482  PQQAGSPLKRPFPAAAPAVAAAAPAPAPAP----AAAPALAAAAVAAAAGGAAPSHSQKP 537
            P+ +  P   P P   PA    + +PA  P    +  P            G+ P     P
Sbjct: 1030 PELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSP 1089

Query: 538  SVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQA 597
             + ++  + R P    PT  +K  P   VR             P  G+  L    KP+  
Sbjct: 1090 -LGVLSGTSRPPT---PTLSLKPTPPAPVRLS---------PAPPPGSSSL---LKPLTV 1133

Query: 598  PGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLN---------------- 641
            P      PA  + +   ++      A   AV A +PAP +  L+                
Sbjct: 1134 PPGYTFPPAAATTTSTTTA-----TATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIG 1188

Query: 642  -----------TPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQ 690
                          G +PLT Q+      LTG Q        ++QL    A   P+P  +
Sbjct: 1189 QLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQ--------VRQL----AVGQPRPLQR 1236

Query: 691  GSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQ-PQPQAAVLSLLGSAQVPQQGVQLPFVLG 749
                 +S  GQ     Q  +V L  A +    P P + + S   S      G+ LP    
Sbjct: 1237 NVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAAN 1296

Query: 750  QQPQPL------LLLQPQPQPQQIQLQTQPLRVLQQPVFLATGAVQIVQPHPGVQAG--- 800
            Q P  +      + +  +  P+       PL    +P   ++G   ++ P P +  G   
Sbjct: 1297 QVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPP--SSGLPAVLNPRPTLTPGRLP 1354

Query: 801  SQLVGQRKGGKPTP 814
            +  +G  +   PTP
Sbjct: 1355 TPTLGTARAPMPTP 1368



 Score = 35.0 bits (79), Expect = 0.28
 Identities = 70/277 (25%), Positives = 104/277 (37%), Gaps = 48/277 (17%)

Query: 463  PRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPA-VAAAAPAP--AP----APAAAP 515
            P+   P+ +  ++  +S  P  A +    P P   P    + APAP  AP     PA A 
Sbjct: 1707 PQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAH 1766

Query: 516  ALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKA 575
             L  A  +++A   AP+  Q  ++         PAA +    + +APA    T S   +A
Sbjct: 1767 TLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQT---LALAPA---STQSPASQA 1820

Query: 576  TNVEGPVRGA---QVLGCSFKPVQAP-------GSGAPAPAGISGSGLQSSGGPLPDARP 625
            +++     GA    V   S  PV           SG P+P     S   S GGP P  +P
Sbjct: 1821 SSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPP----STATSFGGPRPRRQP 1876

Query: 626  GAVQASSPAPLQFFLNTPEGLR--------PLTLQVPQGWAVLTGPQQQSHQLVSLQQLQ 677
                   P    F+L++ E  R            Q+ +    L        +++    L 
Sbjct: 1877 -----PPPPRSPFYLDSLEEKRKRQRSERLERIFQLSEAHGALA--PVYGTEVLDFCTLP 1929

Query: 678  QPTAA--HPPQPGPQGSTLGLSTQGQ----AFPAQQL 708
            QP A+   P  PGP   T    T+       FP Q+L
Sbjct: 1930 QPVASPIGPRSPGPSHPTFWTYTEAAHRAVLFPQQRL 1966



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 70/350 (20%), Positives = 119/350 (34%), Gaps = 40/350 (11%)

Query: 146 VRDYRQSSNMQPPGYQSRHILLRPTMQTLAPEVKTMTRDGEKWSQEDKFPLESQLILATA 205
           +R + +    +    +     LR    T+A +V+    + EK  Q   F  +S+L     
Sbjct: 170 IRHHEEQRQKEERARREEQAKLRRIASTMAKDVRQFWSNVEKVVQ---FKQQSRLEEKRK 226

Query: 206 EPLCLDPSVAVACTANRLLYNKQKMNTDPMEQCLQRYSWPSVKPQQEQSDCPPPPELRVS 265
           + L L     V  T        Q +N  P+    +  S P +      S  PPPP  R+ 
Sbjct: 227 KALDLHLDFIVGQTEKYSDLLSQSLN-QPLTSS-KAGSSPCLGSSSAASS-PPPPASRLD 283

Query: 266 TSG------QKEERKVGQPCELNITKAGSCVDTWKGRPCDLAVPSEVDVEKLAKGYQSVT 319
                    + EE    +  E+   + G+  +  +     L    E+ +E+L +      
Sbjct: 284 DEDGDFQPQEDEEEDDEETIEVEEQQEGNDAEAQRREIELLRREGELPLEELLRSLPPQL 343

Query: 320 AADPQLPVWPAQEVEDPFRHAWEAGCQAWDTKPNIMQSFNDPLLCGKIRPRKKARQKSQK 379
              P  P       +   R   E G +  +  P +++          I+P   A  +  K
Sbjct: 344 LEGPSSPSQTPSSHDSDTRDGPEEGAE--EEPPQVLE----------IKPPPSAVTQRNK 391

Query: 380 SPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSH-SSSGPASVSQL--- 435
            PW P  DD           D    ++ A+E ++ +V    ++S  +  G  S+ +L   
Sbjct: 392 QPWHPDEDDEEFTANEEEAEDEEDTIA-AEEQLEGEVDHAMELSELAREGELSMEELLQQ 450

Query: 436 --------SSWKTPEQPDPVWVQSS---VSGKGEKHPPPRTQLPSSSGKI 474
                   S     E  D V   SS     G  E   PP+    S S  +
Sbjct: 451 YAGAYAPGSGSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSV 500



 Score = 31.2 bits (69), Expect = 4.1
 Identities = 46/158 (29%), Positives = 67/158 (42%), Gaps = 19/158 (12%)

Query: 668  HQLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQ---LLNVNLTGAGSG---LQ 721
            H+L     L+  TA  PP P P+   + ++   Q  P Q+   ++ VN   A  G   ++
Sbjct: 967  HRLSRRVLLEVATAPDPP-PRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVR 1025

Query: 722  PQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQPV 781
            P P   + +      VPQ       VL   P  L++      P  I     P  VL  P+
Sbjct: 1026 PPPGPELSAQPTPGPVPQ-------VL---PASLMVSASPAGPPLIPASRPPGPVLLPPL 1075

Query: 782  FLATGAVQIVQPHP-GVQAG-SQLVGQRKGGKPTPPAP 817
               +G++  V P P GV +G S+        KPTPPAP
Sbjct: 1076 QPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAP 1113


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 56/210 (26%), Positives = 70/210 (33%), Gaps = 37/210 (17%)

Query: 418 GPGKMSHSSS-GPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISS 476
           GPG+        P    Q      P+QP P            + PPP    P        
Sbjct: 50  GPGQSGPKPPIPPPPPHQQQQQPPPQQPPP------------QQPPPHQPPPHPQPHQQQ 97

Query: 477 GNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQK 536
               PPQ +  P+    P  AP V +A PA + AP A P  +    A    G  P+ +  
Sbjct: 98  QPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSG---APPGSGPGPTPTPP 154

Query: 537 PSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQ 596
           P+V     +   P A  PT      P    + G        V GP  G         P Q
Sbjct: 155 PAV-----TSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPG---------PKQ 200

Query: 597 APGSGAPAPAGISGSGLQSSGGPLPDARPG 626
            PG G P        G +  GGP P   PG
Sbjct: 201 GPGPGGP-------KGGKMPGGPKPGGGPG 223



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 46/180 (25%), Positives = 51/180 (28%), Gaps = 18/180 (10%)

Query: 367 IRPRKKARQKSQKSPWQPFPDD---HSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMS 423
           I P    +Q+ Q  P QP P     H     P               S     +GPG   
Sbjct: 60  IPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAP 119

Query: 424 HSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKI---SSGNSF 480
              S P + S       P    P     S  G     PP  T  P  +      SSG   
Sbjct: 120 GVGSAPPASSSAPPATPPTSGAP---PGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPT 176

Query: 481 PPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVP 540
            P QAG P         P   AA P P P P   P           GG  P      S P
Sbjct: 177 TPPQAGGP---------PPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTP 227


>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
          Length = 1711

 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 79/297 (26%), Positives = 113/297 (38%), Gaps = 49/297 (16%)

Query: 410 ESVQSKVKGPGKMSHSSSGPASVS-QLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLP 468
           ++ Q  +  P  + HS   P  V+  + +   P  P P    +         PP    L 
Sbjct: 219 DAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPA---------PPSVPTLI 269

Query: 469 SSSGKIS-SGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAG 527
           S S  +S S +   P  A +P   P P +APA     PAP   P +AP LA   + A   
Sbjct: 270 SDSNPLSVSASVLVPVPASAPPSGPVPLSAPA-----PAPLSVPVSAPPLAL--IQAPVP 322

Query: 528 GAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQV 587
            +AP+    P    + A    PA+  P      +  +   T S+G  +T    P      
Sbjct: 323 PSAPTLVLAPVPTPVLAPM--PASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIP------ 374

Query: 588 LGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNT---PE 644
              +F P   P   AP PA I       +  P+P A P A+  S+P P  F L+    P 
Sbjct: 375 ---AFAPTPVP---APTPAPI----FTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPA 424

Query: 645 GLRPLTLQVP---QGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLST 698
              P   +VP   Q   VLT  Q        L  +  P+   P       +TLG+S+
Sbjct: 425 AQAPAMQKVPLSFQPGTVLTPSQ-------PLVYIPPPSCGQPLSVATLPTTLGVSS 474


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 81/352 (23%), Positives = 123/352 (34%), Gaps = 48/352 (13%)

Query: 411  SVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSS 470
            SV  + K P     S+     +  LSS  +P +   +  ++S+S +G K  P  T  P+ 
Sbjct: 800  SVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFL-PENSLSFQGSKDSPATTHSPTP 858

Query: 471  SGKISS------------GNSFPPQQAGSP--LKRPFPAAAPAVAAAAPAPAPAPAAAPA 516
                 +            G + PP++  +P  +  PFP   PA         PAP  APA
Sbjct: 859  PSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPAT--------PAPKQAPA 910

Query: 517  LAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKAT 576
            L+  + +     A P+    P+ P  K +   PAA  P+   K  PA      +    A 
Sbjct: 911  LSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPS--PKGGPATPSPKWAPTPPAA 968

Query: 577  NVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPL 636
                P  G         P      GAP P   + +     GGP   +  GA     P P 
Sbjct: 969  TPPSPKGG---------PATPSPKGAPTPP--AATPPSPKGGPATPSPKGA-----PTPP 1012

Query: 637  QFFLNTPEGLRPLTLQVPQGWA---VLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGST 693
                 +P+G  P     P+G +     T P  +     +      PT      P P+G  
Sbjct: 1013 AVTPPSPKG-SPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGP 1071

Query: 694  LGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLP 745
               S +G   P         +  G    P P+ A +    +   P+ G+  P
Sbjct: 1072 ATPSLKGAPTPPAA---TPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120



 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 66/233 (28%), Positives = 82/233 (35%), Gaps = 28/233 (12%)

Query: 428  GPASVSQLSSWKTPEQ--PDPVWVQSSVSGKGEKHPPPRTQ---------LPSSSGKISS 476
            GPA+ S   +   P    P P    ++ S KG   PP  T           P   G  + 
Sbjct: 976  GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP 1035

Query: 477  GNSFPPQQAGSPLKRPFPAAAPAV-AAAAPAPAPAPA-----AAPALAAAAVAAAAGG-A 529
              + PP   GSP   P P  AP   AA  P+P   PA      AP   AA   +  GG A
Sbjct: 1036 PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPA 1095

Query: 530  APSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLG 589
             PS    P  P   A+   P  G  T   K AP     T  +  K      P +GA    
Sbjct: 1096 TPSPKGAPMPP--AATPPSPKGGLATPPHKGAPTTPAATPPSP-KGGLATPPPKGAPTTP 1152

Query: 590  CSFKPVQAPGSGAPAPAGI----SGSGLQSSGG---PLPDARPGAVQASSPAP 635
             +  P    G   P P G     + +     GG   P P   P    A+ P+P
Sbjct: 1153 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1205



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 108/447 (24%), Positives = 139/447 (31%), Gaps = 77/447 (17%)

Query: 417  KGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISS 476
            +GP   +   +   S++  S  K    P P  + +S S KG   PP  T      G  + 
Sbjct: 898  EGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATP 957

Query: 477  GNSF--------PPQQAG-----SPLKRPFPAAA----PAVAAAAPAP--APAPAA---- 513
               +        PP   G     SP   P P AA    P    A P+P  AP P A    
Sbjct: 958  SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP 1017

Query: 514  APALAAAAVAAAAGGAAPSHSQKPS-------VPLIKASRRRPAAGRPTRFVKIAPAIQV 566
            +P  + AA     G + P  +  PS        PL K +   PAA  P+   K  PA   
Sbjct: 1018 SPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS--PKGGPATPS 1075

Query: 567  RTGSTGLKATNVEGPVRGAQV---LGCSFKPVQAPGS-----------GAP-APAGISGS 611
              G+    A     P  G       G    P   P S           GAP  PA    S
Sbjct: 1076 LKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPS 1135

Query: 612  GLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLV 671
                   P P   P    A+ P+P       P    P T            P      L 
Sbjct: 1136 PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTT--------PAATPPSPKGGLA 1187

Query: 672  SLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSL 731
            +      PT      P P+G   GL+T               +  G    P P+ A  + 
Sbjct: 1188 TPSPKGAPTTPAATPPSPKG---GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1244

Query: 732  LGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQ--LQTQPLRVLQQPVFLATGAVQ 789
              +   P+ G   P   G  P P     P   P  ++  L T P +    P         
Sbjct: 1245 AATPPSPKGGPATPPPKG-APTP-----PAATPPSLKGGLATPPHKGAPNPAV------- 1291

Query: 790  IVQPHPGVQAGSQLVGQRKGGKPTPPA 816
            +  P P    G       KG  PTPPA
Sbjct: 1292 VTPPSP---KGGPATSPPKGA-PTPPA 1314



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 91/394 (23%), Positives = 126/394 (31%), Gaps = 66/394 (16%)

Query: 431  SVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLK 490
            +V  LS  K P  P      ++   KG+  PP  T +       +S     P    S   
Sbjct: 1406 AVIPLSPKKAPATP-VTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGD 1464

Query: 491  RPFPAAAPAVAAAAPAP-----APAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKAS 545
               PA  P      PAP     + +P  APA  A   A       PS  ++  VP   +S
Sbjct: 1465 PTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKE--VPATPSS 1522

Query: 546  RRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAP 605
            RR P A   T   K  PA      +    A  V  P +   +      P       A +P
Sbjct: 1523 RRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSP 1582

Query: 606  AGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQ 665
              ++ S  + +  P     P AV + SP                                
Sbjct: 1583 PAVTPSTYKGAPSPKELLIPPAVTSPSP-------------------------------- 1610

Query: 666  QSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQP- 724
                    ++   P A  PP P           +G A PA +    +     S L+  P 
Sbjct: 1611 --------KEAPTPPAVTPPSP----------EKGPATPAPKGTPTSPPVTPSSLKDSPT 1652

Query: 725  -QAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQPVFL 783
              A+V   +G A VPQ    LP   G  P  L  +   P P+   + T P R   Q    
Sbjct: 1653 SPASVTCKMG-ATVPQASKGLPAKKG--PTALKEVLVAPAPESTPIITAPTRKGPQTKKS 1709

Query: 784  ATGAVQIVQPHPGVQAGSQLVGQRKGGKPTPPAP 817
            +  +  I  P P  + GS+  G      P P  P
Sbjct: 1710 SATSPPIC-PDPSAKNGSK--GPLSTVAPAPLLP 1740



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 86/371 (23%), Positives = 126/371 (33%), Gaps = 64/371 (17%)

Query: 429  PASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQ-QAGS 487
            P +++  S  KTP  P P    ++ S K    PP  T               PP   + S
Sbjct: 1550 PPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPS 1609

Query: 488  PLKRPFPAA----APAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIK 543
            P + P P A    +P    A PAP   P + P   ++   +    A+ +     +VP  +
Sbjct: 1610 PKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVP--Q 1667

Query: 544  ASRRRPAAGRPT--RFVKIAPAIQ--------VRTGSTGLKATNVEGPVRGAQVLGCSFK 593
            AS+  PA   PT  + V +APA +         R G    K++    P+       C   
Sbjct: 1668 ASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPI-------CPDP 1720

Query: 594  PVQAPGSG-----APAP-------AGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLN 641
              +    G     APAP       +  +  G  +S  P     P   +AS+P     F  
Sbjct: 1721 SAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAF-- 1778

Query: 642  TPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQ 701
                     L  P+  +V   P       VSL     P    PP+     S+ GL  +  
Sbjct: 1779 ------EKVLPKPESASVSAAPSPP----VSLPLAPSPVPTLPPKQQFLPSSPGLVLESP 1828

Query: 702  AFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQ 761
            + P               L P  +  +L L+    +   GV    VL   P P     P 
Sbjct: 1829 SKP---------------LAPADEDELLPLIPPEPI-SGGVPFQSVLVNMPTPKSAGIPV 1872

Query: 762  PQPQQIQLQTQ 772
            P P   Q  T+
Sbjct: 1873 PTPSAKQPVTK 1883



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 63/289 (21%), Positives = 98/289 (33%), Gaps = 21/289 (7%)

Query: 498 PAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSH----SQKPSVPLIKASRRRPAAGR 553
           PA     P P    A  P  +A +V AA G   P+     S  P    + A+ +      
Sbjct: 10  PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPS 69

Query: 554 PTRFVKI---APAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISG 610
           P+         P  Q  +G+     T  E P     ++G    P     +       + G
Sbjct: 70  PSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKG 129

Query: 611 SGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLT--GPQQQSH 668
           +   S+   L    P +VQ SS  P     + P      ++ V +  +V+T   P   S 
Sbjct: 130 TPSSSAPLALVALAPHSVQKSSAFPPNLLTSPP------SVAVAESGSVITLSAPIAPSE 183

Query: 669 QLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAV 728
              +L ++  P+   P   G       +ST     P   +  +    +G    PQ     
Sbjct: 184 PKTNLNKV--PSEVVPNPKGTPSPPCIVST----VPYHCVTPMASIQSGVASLPQTTPTT 237

Query: 729 LSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVL 777
              + S QV    +    +  Q P  L L  P   P  + L TQ L V+
Sbjct: 238 TLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVV 286



 Score = 39.3 bits (90), Expect = 0.015
 Identities = 70/276 (25%), Positives = 89/276 (32%), Gaps = 40/276 (14%)

Query: 444  PDPVWVQSSVSGKGEKHPPPRTQ--------LPSSSGKISSGNSFPPQQAGSPLKRPFPA 495
            P P    ++   KG   PP  T          P   G  +     PP   G P   P   
Sbjct: 1249 PSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKG 1308

Query: 496  AAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPT 555
            A    AA  P+P  +P   P   A    A      PS    P++P    S +    G  T
Sbjct: 1309 APTPPAATPPSPKGSPGTPPPKGAPTPPAV---TPPSPKGTPTLPATTPSSK---GGPTT 1362

Query: 556  RFVKIAPAIQVRTGS-TGLKATNVEGPVRGAQV---LGCSFKPVQAPGSGAPAPAGISGS 611
               K  P     T S  G  A     P RG  +    G    P   P S   APA     
Sbjct: 1363 PSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPA----- 1417

Query: 612  GLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTL-QVPQGWAVLTGPQQQSHQ- 669
                     P  R GA   S          TP  + P++L + P   A   GP   S + 
Sbjct: 1418 --------TPVTREGAATPSKGD------LTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463

Query: 670  LVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPA 705
              +L  +  P+   PP P  Q +T     +  A PA
Sbjct: 1464 DPTLPAVTPPSPKEPPAP-KQVATSSSPKKAPATPA 1498



 Score = 37.4 bits (85), Expect = 0.057
 Identities = 62/261 (23%), Positives = 96/261 (36%), Gaps = 23/261 (8%)

Query: 449 VQSSVSGKGEKHPPPRT----QLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAA 504
           V +++   G   PPP +    Q P S+   +S    P   A +PL+ PFP ++   A   
Sbjct: 34  VTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPL 93

Query: 505 PAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSV-PLIKASRRRPAAGRPTRFVKIAP- 562
                AP   P L    ++ AA   A      P + P +K +   P++  P   V +AP 
Sbjct: 94  GTAPEAPTFLPNLIGPPISPAALALA-----SPMIAPTLKGT---PSSSAPLALVALAPH 145

Query: 563 AIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPD 622
           ++Q    S+      +  P   A     S   + AP   AP+    + + + S   P P 
Sbjct: 146 SVQ---KSSAFPPNLLTSPPSVAVAESGSVITLSAP--IAPSEPKTNLNKVPSEVVPNPK 200

Query: 623 ARPGAVQASSPAPLQF---FLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVS-LQQLQQ 678
             P      S  P        +   G+  L    P     +  PQ +   + S L   Q 
Sbjct: 201 GTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQN 260

Query: 679 PTAAHPPQPGPQGSTLGLSTQ 699
           P +     P    + L LSTQ
Sbjct: 261 PGSLSLKGPVSPPAALSLSTQ 281



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 58/241 (24%), Positives = 84/241 (34%), Gaps = 37/241 (15%)

Query: 402  GRAVSQAQESVQSKVKGPGKMSHSSSGPASVS---------------QLSSWKTPEQPDP 446
            G  V QA + + +K KGP  +      PA  S               + S+   P  PDP
Sbjct: 1662 GATVPQASKGLPAK-KGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDP 1720

Query: 447  VWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSF----------PPQQAGSPL-KRPFPA 495
                 S        P P   +   S K + G             P  +A +PL    F  
Sbjct: 1721 SAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEK 1780

Query: 496  AAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVP-LIKASRRRPAAGRP 554
              P   +A+ + AP+P  +  LA + V        P     PS P L+  S  +P A  P
Sbjct: 1781 VLPKPESASVSAAPSPPVSLPLAPSPVPT----LPPKQQFLPSSPGLVLESPSKPLA--P 1834

Query: 555  TRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQ 614
                ++ P I     S G+   +V   +   +  G    PV  P +  P      GSG +
Sbjct: 1835 ADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGI---PVPTPSAKQPVTKNNKGSGTE 1891

Query: 615  S 615
            S
Sbjct: 1892 S 1892



 Score = 34.3 bits (77), Expect = 0.48
 Identities = 38/132 (28%), Positives = 54/132 (40%), Gaps = 16/132 (12%)

Query: 475 SSGNSFPPQQAGSPLKRPFPA---AAPAVAAAAPAPAPAPAAAPALAAAAVAAAAG--GA 529
           S+G S+P Q++  P   P P+     PA  AA P  AP+    P+  ++   + +G    
Sbjct: 345 STGASYPSQRSVIP---PLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNV 401

Query: 530 APSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATN----VEGPVRGA 585
           A S S  P+  LI  S   P A      V   P   V  G+T L  TN       P    
Sbjct: 402 ATSFSLSPTTSLILKS--SPNATYHYPLVAQMPVSSV--GTTPLVVTNPCTIAAAPTTTF 457

Query: 586 QVLGCSFKPVQA 597
           +V  C   P+ +
Sbjct: 458 EVATCVSPPMSS 469


>gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithorax
            homolog, Drosophila); translocated to, 6 [Homo sapiens]
          Length = 1093

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 78/283 (27%), Positives = 105/283 (37%), Gaps = 31/283 (10%)

Query: 489  LKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRR 548
            L  PFPA  PA   AA  P P P   P  A ++ + +   + P  S       +  S   
Sbjct: 757  LSVPFPAL-PAALPAANGPVPGPYGLPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSED 815

Query: 549  PAAGRPTRFVKI---------APAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPG 599
            P +G P+R              P +Q    +  L       P+      G    P  A  
Sbjct: 816  PHSGCPSRSSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGAAGL 875

Query: 600  SGAPAPAGISGSGLQSSGG-PLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWA 658
               P   G+ G GL  SGG PL     G   A++P P      +  G  P TLQ+P    
Sbjct: 876  GAMPMAEGLLG-GLAGSGGLPLNGLLGGLNGAAAPNPASL---SQAGGAP-TLQLPGCLN 930

Query: 659  VLTGPQQQSH----QLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLT 714
             LT  +QQ H    Q   LQQLQQ  A+  PQ  P+  T+      Q    ++L  + + 
Sbjct: 931  SLT--EQQRHLLQQQEQQLQQLQQLLAS--PQLTPEHQTVVYQMIQQIQQKRELQRLQMA 986

Query: 715  GAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLL 757
            G         Q  + SLL  +  P      P +L     P LL
Sbjct: 987  GGS-------QLPMASLLAGSSTPLLSAGTPGLLPTASAPPLL 1022



 Score = 33.9 bits (76), Expect = 0.63
 Identities = 62/298 (20%), Positives = 98/298 (32%), Gaps = 36/298 (12%)

Query: 368 RPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESV--QSKVKGPGKMSHS 425
           + +++ +QK +K P  P      + L P     A +  S A  S   ++  +   + S  
Sbjct: 243 KDKERLKQKHKKRPESP-----PSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRE 297

Query: 426 SSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQA 485
           S G  S S   S K  +      V S  S          +        +SS  S P   A
Sbjct: 298 SKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSA 357

Query: 486 GSPLKRPFPAAAPAVAAAAPAPAPAPAA------------------APALAAAAVAAAAG 527
              L++P         A AP+  P+P+A                   P +  +   +++G
Sbjct: 358 FPKLEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSG 417

Query: 528 GA-APSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQ 586
            A APS     S P +  S       +    +   P     T  TGLK    +   R   
Sbjct: 418 RARAPSPGDYKS-PHVTGSGASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRH 476

Query: 587 VLGCSFKPVQAPGSGAPAPAGISGSGLQS---------SGGPLPDARPGAVQASSPAP 635
             G         G+G PA   +  + L           SGG L  +  G + + +  P
Sbjct: 477 GPGRPKGSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGP 534



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 3/91 (3%)

Query: 465  TQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAA 524
            +QLP +S  + +G+S P   AG+P   P  +A P + A A            +AAAA AA
Sbjct: 989  SQLPMAS--LLAGSSTPLLSAGTPGLLPTASAPPLLPAGALVAPSLGNNTSLMAAAAAAA 1046

Query: 525  A-AGGAAPSHSQKPSVPLIKASRRRPAAGRP 554
            A A    P      + P +  S    + G P
Sbjct: 1047 AVAAAGGPPVLTAQTNPFLSLSGAEGSGGGP 1077


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 97/409 (23%), Positives = 143/409 (34%), Gaps = 50/409 (12%)

Query: 386 PDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPD 445
           P   S   RPG     G  +S  +   + K     K S  S+G     + +S  TP  P 
Sbjct: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAG---ARRDTSGPTPGTPS 173

Query: 446 PVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAP 505
           P   + S +   E   P     P+ S +       P      P K    A+  +    +P
Sbjct: 174 PAMARRSRAAGTEVGLPR----PAPSAR-------PRPPTEGPRKSVSSASEHSTTEPSP 222

Query: 506 APAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQ 565
           A    P+A   L   A  + +  A P  S   S P  + + R PA           P+  
Sbjct: 223 AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA----------HPSQP 272

Query: 566 VRTGSTGLKATNVEGPVR-GAQVLGCSFKPVQAPGSGAPAPAGISGSGL---QSSGGPLP 621
              G   L+   V  P +  A  LG    P+ +     P+P+G     +    ++  PLP
Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALG----PLSSSPLATPSPSGTKARPVPPPDNAATPLP 328

Query: 622 DARPGAVQASSPAPLQFFLNTPEGLRPLTLQ-------VPQGWA---VLTGPQQQSHQLV 671
              P +   ++P PL      P    P +LQ        P   A   + T P Q    L 
Sbjct: 329 ATLPPSPPLATPLPLA----PPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQ 384

Query: 672 SLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQP-QPQAAVLS 730
           ++  +Q P +   P      S L LS+  QA  +     +  T +   + P Q QA++ S
Sbjct: 385 TIPPIQVPHSLTSPSLQAPPSPLALSSL-QATTSLGSPTLQATHSFLTMSPRQTQASLTS 443

Query: 731 LLGSAQVPQQG--VQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVL 777
               A  P     +Q P  L   P     L P   P    L   PL+ L
Sbjct: 444 PSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL 492



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 66/263 (25%), Positives = 93/263 (35%), Gaps = 42/263 (15%)

Query: 461  PPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVA-----------AAAPAPAP 509
            PPPR     ++  +    S P     SPL +P P A PA+A           A+ P  AP
Sbjct: 753  PPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAP 812

Query: 510  ---------APAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKI 560
                     +P A P   A  V AA     P     P+ P ++A RR P  G  T     
Sbjct: 813  FSPSASLPMSPLATPPPQAPPVLAAPLLQVP--PSPPASPTLQAPRRPPTPGPDTSVSGP 870

Query: 561  APAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPL 620
               + +  G     + +    + G  + G S      P       +G  G    ++  P 
Sbjct: 871  RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG---AAASPP 927

Query: 621  PDARPGAVQASS----PAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQL 676
            PDA   A   ++    PAP   F   P          P  W   TGP   +  L ++ + 
Sbjct: 928  PDAELAACHPAAWSRGPAPPLAFRGAP--------GAPLPWPPATGP-GSADGLCTIYET 978

Query: 677  QQPTAAHPP----QPGPQGSTLG 695
            + P +A P      PGP   T G
Sbjct: 979  EGPESATPAPGALDPGPSPGTSG 1001



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 68/246 (27%), Positives = 84/246 (34%), Gaps = 56/246 (22%)

Query: 461 PPPRTQLPSS-------SGKISSGNSFPPQQAGSPLKRPF--PAAAPAVAAAAPAP-APA 510
           P P  Q P S       S   +  +  PP  A  PL+ P   PA+ P   +A P P AP 
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 728

Query: 511 PAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGS 570
           P AAP L       A+   +PS +  P VP + A                AP +QV    
Sbjct: 729 PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLA----------------APPLQV---- 768

Query: 571 TGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQA 630
                     P     +   +  P QAP + A  P       L S     P   P +  A
Sbjct: 769 -------PPSPPASLPMSPLAKPPPQAPPALATPPL----QALPSPPASFPGQAPFSPSA 817

Query: 631 SSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGP-QQQSHQLVSLQQLQQPTAAHPPQPGP 689
           S P            + PL    PQ   VL  P  Q      +   LQ P    PP PGP
Sbjct: 818 SLP------------MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP--RRPPTPGP 863

Query: 690 QGSTLG 695
             S  G
Sbjct: 864 DTSVSG 869



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 52/209 (24%), Positives = 72/209 (34%), Gaps = 47/209 (22%)

Query: 361  PLLCGKIRPRKKARQKSQKSPWQPFPDDH------SACLRPGSETDAGRAVSQAQESVQS 414
            PLL     P      ++ + P  P PD        +  L PG      R+ S       S
Sbjct: 838  PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS-------S 890

Query: 415  KVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKI 474
             + GP    HSSS  ++  +L  +            S   G     PPP  +L +     
Sbjct: 891  TLSGPDLAGHSSSATSTPEELRGY-----------DSGPEGGAAASPPPDAELAACHPAA 939

Query: 475  SSGNSFPPQQ----AGSPLKRPFPAAAPAVA-------------AAAPA-----PAPAPA 512
             S    PP       G+PL  P PA  P  A             +A PA     P P+P 
Sbjct: 940  WSRGPAPPLAFRGAPGAPLPWP-PATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 998

Query: 513  AAPALAAAAVAAAAGGAAPSHSQKPSVPL 541
             +   AAA   A A   +P  ++   +PL
Sbjct: 999  TSGGKAAAGAGAGASSRSPKQARLGELPL 1027



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 106/504 (21%), Positives = 160/504 (31%), Gaps = 73/504 (14%)

Query: 369 PRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSG 428
           P  +   ++   P QP P    A LRP   T   +  + A   + S        S + + 
Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQA-LRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR 315

Query: 429 PASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSP 488
           P      ++   P    P    S          PP    P S   + S  + PP QA   
Sbjct: 316 PVPPPDNAATPLPATLPP----SPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS 371

Query: 489 LKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAA----------------------- 525
           +  P   A P++    P   P    +P+L A     A                       
Sbjct: 372 MTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLT 431

Query: 526 -------AGGAAPSH--SQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGS------ 570
                  A   +PS   S  P  P ++A    PA+  P     ++PA+   +        
Sbjct: 432 MSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPAS--PPLQTSLSPAVSPLSSPLTIHPL 489

Query: 571 ---TGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGA 627
              + L + + + P+    +     +   AP S    PA ++   L++    LP   P  
Sbjct: 490 QALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLEN----LPSLAPPP 545

Query: 628 VQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTA-AHPPQ 686
           +Q +S       L TP    P  LQ P   + LT P  ++   ++    Q P A A PP 
Sbjct: 546 LQTASAPLTTPHLETPPCPAPCPLQAPP--SPLTTPPPETPSSIATPPPQAPPALASPPL 603

Query: 687 PG------------PQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGS 734
            G            P  +   L+      P     +  L+   +     P A  + LL +
Sbjct: 604 QGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA 663

Query: 735 --AQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQPVFLATGAVQIVQ 792
             +  P   VQ PF     P P+      P      L   PL+V   P            
Sbjct: 664 PFSPPPSPPVQAPFSPPASP-PVSPSATPPSQAPPSLAAPPLQVPPSP---PASPPMSPS 719

Query: 793 PHPGVQAGSQLVGQRKGGKPTPPA 816
             P  QA   L        P+PPA
Sbjct: 720 ATPPPQAPPPLAAPPLQVPPSPPA 743



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 70/292 (23%), Positives = 97/292 (33%), Gaps = 31/292 (10%)

Query: 484 QAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAG--GAAPSHSQKPSVPL 541
           +AG+  + P  A AP +    P  +P P      AA  V  AAG  G  P   +   +  
Sbjct: 9   KAGAAARTP-AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG 67

Query: 542 IKASRRRPAAGRPTRFVKIA---PAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAP 598
                  P AG PTR    +   PA +      G +A   +    G         PV +P
Sbjct: 68  ATIPESAPRAG-PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG---------PVSSP 117

Query: 599 G--SGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQG 656
           G  SG   P  +   GL+ S      AR  A +A   + L        G R  T     G
Sbjct: 118 GRASGTTRPGPLGQKGLRISAEETV-ARGKATEAPKRSALS------AGARRDTSGPTPG 170

Query: 657 W--AVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLT 714
                +    + +   V L +        PP  GP+ S    S      P+         
Sbjct: 171 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR--RRP 228

Query: 715 GAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQ 766
            AG GLQ     ++ S       P +    P   G    P    QP+P+  Q
Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARSG--PSARGTPRAPAHPSQPKPKGLQ 278


>gi|7662346 ADNP homeobox 2 [Homo sapiens]
          Length = 1131

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 84/320 (26%), Positives = 118/320 (36%), Gaps = 32/320 (10%)

Query: 494 PAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAA-----GGAAPSHSQKPSVPLIKASRR- 547
           PA  P    A P  +P+PAA   +  A  A  +       A  SH    S PL       
Sbjct: 286 PAQPPCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSL 345

Query: 548 --RPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAP 605
             +P A +P  F+     +        L  +   GPV  +  +G S  P+         P
Sbjct: 346 TLQPPAPQPV-FLSHGVPLHQSVNPPVLPLSQPVGPVNKS--VGTSVLPINQTVRPGVLP 402

Query: 606 AGISGSGLQSSGGP-----LPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGW--- 657
                  +    GP      P   PG +QA SP  L      P G+ P     P G    
Sbjct: 403 LTQPVGPINRPVGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAGQMTPAGQMTP 462

Query: 658 -AVLTGPQQQSHQLVSLQQLQQ------PTAAHPPQPGPQGSTLGLSTQGQAFPAQQLLN 710
             V+ G    S  L + Q +Q        TA     P  Q + L + + GQ  P+  LL+
Sbjct: 463 AGVIPGQTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQTAPLRVISAGQVVPS-GLLS 521

Query: 711 VNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQ 770
            N T + S + P  Q     +L  +Q    GV LP  +GQ  +P +L   Q     I   
Sbjct: 522 PNQTVSSSAVVPVNQGVNSGVLQLSQPVVSGV-LP--VGQPVRPGVLQLNQTVGTNILPV 578

Query: 771 TQPLR--VLQQPVFLATGAV 788
            QP+R    Q   FL +G++
Sbjct: 579 NQPVRPGASQNTTFLTSGSI 598



 Score = 38.1 bits (87), Expect = 0.033
 Identities = 76/307 (24%), Positives = 111/307 (36%), Gaps = 39/307 (12%)

Query: 373 ARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSS----SG 428
           A   +  +P QP P  H A  +      AG+ V+ AQ +  S    P     S     S 
Sbjct: 278 ANGSAPSAPAQP-PCFHLALPQNSPSPAAGQPVTVAQGAPGSLTHSPPAAGQSHMTLVSS 336

Query: 429 PASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPP--PRTQLPSSSGKISSGNS------- 479
           P  V Q S    P  P PV++   V      +PP  P +Q P      S G S       
Sbjct: 337 PLPVGQNSLTLQPPAPQPVFLSHGVPLHQSVNPPVLPLSQ-PVGPVNKSVGTSVLPINQT 395

Query: 480 -----FPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVA-AAAGGAAPSH 533
                 P  Q   P+ RP     P V   +P+  P    A +    +V+ A   G  P+ 
Sbjct: 396 VRPGVLPLTQPVGPINRP---VGPGVLPVSPSVTPGVLQAVSPGVLSVSRAVPSGVLPAG 452

Query: 534 SQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVL-GCSF 592
              P      A +  PA   P    + A +  + TG          G    ++VL     
Sbjct: 453 QMTP------AGQMTPAGVIPG---QTATSGVLPTGQMVQSGVLPVGQTAPSRVLPPGQT 503

Query: 593 KPVQAPGSGAPAPAG-ISGSGLQSSGGPLP---DARPGAVQASSPAPLQFFLNTPEGLRP 648
            P++   +G   P+G +S +   SS   +P       G +Q S P  +   L   + +RP
Sbjct: 504 APLRVISAGQVVPSGLLSPNQTVSSSAVVPVNQGVNSGVLQLSQPV-VSGVLPVGQPVRP 562

Query: 649 LTLQVPQ 655
             LQ+ Q
Sbjct: 563 GVLQLNQ 569


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 60/197 (30%), Positives = 76/197 (38%), Gaps = 27/197 (13%)

Query: 492 PFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSV---------PLI 542
           P PA  PA     PAPAPAPA APALA+AA         P     P V         P+ 
Sbjct: 505 PTPATTPA-----PAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVE 559

Query: 543 KASRR--RPAAGRPT---------RFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCS 591
             +RR  RPA  RPT         R    AP +   +GS G     +   + G+ +   +
Sbjct: 560 DMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQA-LPRRLVGSSLRAPT 618

Query: 592 FKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTL 651
             P   P    PA      S    S      A P  V  S+PA +     T EG  P  +
Sbjct: 619 VPPPLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAATAEGGAPEAI 678

Query: 652 Q-VPQGWAVLTGPQQQS 667
             VP   A+   P+ +S
Sbjct: 679 SGVPTPPAIPPQPRPRS 695



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 38/129 (29%), Positives = 50/129 (38%), Gaps = 22/129 (17%)

Query: 439 KTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPF----- 493
           K P    P      VSG   +  PP   LP  SG   +  + P +  GS L+ P      
Sbjct: 566 KRPAPARPTMPPPQVSGS--RSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPL 623

Query: 494 ------PA--------AAPAVAAAAPA-PAPAPAAAPALAAAAVAAAAGGAAPSHSQKPS 538
                 PA        A+P+ A+  PA P+P   + PA      A A GGA  + S  P+
Sbjct: 624 PPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAATAEGGAPEAISGVPT 683

Query: 539 VPLIKASRR 547
            P I    R
Sbjct: 684 PPAIPPQPR 692



 Score = 35.0 bits (79), Expect = 0.28
 Identities = 45/175 (25%), Positives = 61/175 (34%), Gaps = 15/175 (8%)

Query: 461 PPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAV---AAAAPAPAPA-PAAAPA 516
           P P   L S++ K  + +  PP+ A   + R  P  A  V   A     PAPA P   P 
Sbjct: 519 PAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVEDMARRTKRPAPARPTMPPP 578

Query: 517 LAAAAVAAAAGGAAPSHSQKPSVP------LIKASRRRPAAGRPTRFVKIAPAIQVRTGS 570
             + + ++      P  S  P  P      L+ +S R P    P       PA +    S
Sbjct: 579 QVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRS 638

Query: 571 TGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARP 625
               +    GP   + V      P Q     A A  G   +    SG P P A P
Sbjct: 639 PASPSPASPGPASPSPV--SLSNPAQVDLGAATAEGGAPEA---ISGVPTPPAIP 688


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 92/359 (25%), Positives = 133/359 (37%), Gaps = 71/359 (19%)

Query: 463  PRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAA----PALA 518
            P+  LPS +   S+    P QQ  +P + P P A P  +  + +PA  P+ A    P   
Sbjct: 1840 PQQSLPSPT---SAPPGTPTQQPSTP-QTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTV 1895

Query: 519  AAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGL----- 573
            +     +   A P  +Q P   +  A +    A +     ++     +  G TG+     
Sbjct: 1896 STGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGS 1955

Query: 574  ----------KATNVEGPVRGAQVLG---CSFKPVQAPGSGAPAPAGISGSGLQSSGGP- 619
                      +   V GPV  +   G    +  P Q P  G P P  IS     +  GP 
Sbjct: 1956 QMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPV-ISMQAQAAVAGPR 2014

Query: 620  LPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQ---- 675
            +P  +P   ++ SP+ LQ  L         TL+ P      + PQQQ   L  L+     
Sbjct: 2015 MPSVQP--PRSISPSALQDLLR--------TLKSP------SSPQQQQQVLNILKSNPQL 2058

Query: 676  ----LQQPTAAH-------PPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAG---SGLQ 721
                ++Q TA +        PQPG Q S  G+  Q        L N+N   AG    G+ 
Sbjct: 2059 MAAFIKQRTAKYVANQPGMQPQPGLQ-SQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVP 2117

Query: 722  PQ--------PQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQ 772
            PQ        PQ   L+++     P      P       + LL  Q Q Q QQ Q Q Q
Sbjct: 2118 PQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQ 2176



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 69/318 (21%), Positives = 109/318 (34%), Gaps = 58/318 (18%)

Query: 422 MSHS----SSGPASVSQLSSWKTPEQPDPVWVQSS---VSGKGEKHPPPRTQLPSSSGKI 474
           M+HS    S G      +S  + P+ P+ +   ++        +    P+ Q PSSSG +
Sbjct: 709 MNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAM 768

Query: 475 SSGNSFPPQQAG------------SPLKRPFPAAA----PAVAAAAPAPAPAPAAAPALA 518
           S G   PP Q G            +PL    P A+    P V  +   P P PA+  A  
Sbjct: 769 SVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGM 828

Query: 519 AAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNV 578
            +       G  P     P+ P    S    +   PT      P+      +T  ++T  
Sbjct: 829 PSLQHTTPPGMTPPQPAAPTQPSTPVS---SSGQTPTPTPGSVPS------ATQTQSTPT 879

Query: 579 EGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQF 638
                 AQV      PVQ P    P  +       Q    P+    PG   + + A +  
Sbjct: 880 VQAAAQAQVTPQPQTPVQPPSVATPQSS-------QQQPTPVHAQPPGTPLSQAAASIDN 932

Query: 639 FLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLST 698
            + TP  +           A      QQ    V + +++  T A   +P P         
Sbjct: 933 RVPTPSSV-----------ASAETNSQQPGPDVPVLEMKTETQAEDTEPDP--------G 973

Query: 699 QGQAFPAQQLLNVNLTGA 716
           + +  P  +++  +L GA
Sbjct: 974 ESKGEPRSEMMEEDLQGA 991



 Score = 37.0 bits (84), Expect = 0.074
 Identities = 130/576 (22%), Positives = 179/576 (31%), Gaps = 142/576 (24%)

Query: 356  QSFNDPLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSK 415
            Q     L   ++  R+ A   ++  P Q  P   SA   PG+ T         Q   Q +
Sbjct: 1815 QQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSA--PPGTPTQQPSTPQTPQPPAQPQ 1872

Query: 416  VKGPGKMSHSSSGPASV---------------SQLSSWKTPEQPDPVWVQSSVSGKGEKH 460
               P  +S S +G  SV               SQ+ +   P QP P  V+++   + E  
Sbjct: 1873 ---PSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQ 1929

Query: 461  --------------PPPRTQL--PSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAA 504
                          PP RT +  P S     S N   P Q   P+    P+  P     A
Sbjct: 1930 QQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPV---MPSMPPGQWQQA 1986

Query: 505  PAPAPAPAAA---PALAAAAVAAAAGGAAPSHS-----------------QKPSVP---- 540
            P P   P      P ++  A AA AG   PS                   + PS P    
Sbjct: 1987 PLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQ 2046

Query: 541  ----LIKASRRRPAA---GRPTRFVKIAPAIQVRTGSTGLKATNVE-GPVRGAQVLGCSF 592
                ++K++ +  AA    R  ++V   P +Q + G         + G  +   +   + 
Sbjct: 2047 QVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNA 2106

Query: 593  KPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQ 652
                 P  G P      G GL   G  L    PG     +P          E LR   LQ
Sbjct: 2107 MQAGVPRPGVPPQQQAMG-GLNPQGQALNIMNPG----HNPNMASMNPQYREMLRRQLLQ 2161

Query: 653  VPQGWAVLTGPQQQSHQ--------LVSLQQLQQPTA--AHPP-----QPGPQGSTLGLS 697
              Q        QQQ  Q        +    Q QQP     +PP     Q   Q   L  S
Sbjct: 2162 QQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGS 2221

Query: 698  TQGQ-AFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLP----------F 746
            + GQ A    QL  +   G G+   P  Q A+   +   Q  +Q +  P           
Sbjct: 2222 SMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQH 2281

Query: 747  VLGQQPQ------------------------------------PLLLLQPQPQPQQIQLQ 770
            +L  QPQ                                    P   +QPQP P  +  Q
Sbjct: 2282 MLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQ 2341

Query: 771  TQPLRVLQQPVFLATGAVQIVQPHPGVQAGSQLVGQ 806
            T        P    T A  I Q H G    S ++ Q
Sbjct: 2342 TGS----PHPGLAVTMASSIDQGHLGNPEQSAMLPQ 2373



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 59/222 (26%), Positives = 75/222 (33%), Gaps = 32/222 (14%)

Query: 619 PLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQ 678
           P P A+P  +  + P       N P  L    +QV QG          + QL   Q    
Sbjct: 648 PAPGAQPPVIPQAQPVRPP---NGPLSLPVNRMQVSQGMNSFNPMSLGNVQLP--QAPMG 702

Query: 679 PTAAHPPQPGPQGSTLGLSTQGQAF-PAQQLLNVNLTG-----------AGSGLQPQ--- 723
           P AA P     Q +++G S  G A  P++     N+ G           A S   PQ   
Sbjct: 703 PRAASPMNHSVQMNSMG-SVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQF 761

Query: 724 PQAAVLSLLGSAQVP-QQGVQLPFVLGQQ-PQPLLLLQPQPQPQQIQLQTQ-PLRVLQQP 780
           P ++    +G  Q P Q GV    V G   P PL +L PQ         TQ PL     P
Sbjct: 762 PSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPP 821

Query: 781 VFLATGAVQI--------VQPHPGVQAGSQLVGQRKGGKPTP 814
              A G   +          P P             G  PTP
Sbjct: 822 ASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTP 863


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 92/359 (25%), Positives = 133/359 (37%), Gaps = 71/359 (19%)

Query: 463  PRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAAA----PALA 518
            P+  LPS +   S+    P QQ  +P + P P A P  +  + +PA  P+ A    P   
Sbjct: 1878 PQQSLPSPT---SAPPGTPTQQPSTP-QTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTV 1933

Query: 519  AAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGL----- 573
            +     +   A P  +Q P   +  A +    A +     ++     +  G TG+     
Sbjct: 1934 STGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGS 1993

Query: 574  ----------KATNVEGPVRGAQVLG---CSFKPVQAPGSGAPAPAGISGSGLQSSGGP- 619
                      +   V GPV  +   G    +  P Q P  G P P  IS     +  GP 
Sbjct: 1994 QMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPV-ISMQAQAAVAGPR 2052

Query: 620  LPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQ---- 675
            +P  +P   ++ SP+ LQ  L         TL+ P      + PQQQ   L  L+     
Sbjct: 2053 MPSVQP--PRSISPSALQDLLR--------TLKSP------SSPQQQQQVLNILKSNPQL 2096

Query: 676  ----LQQPTAAH-------PPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAG---SGLQ 721
                ++Q TA +        PQPG Q S  G+  Q        L N+N   AG    G+ 
Sbjct: 2097 MAAFIKQRTAKYVANQPGMQPQPGLQ-SQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVP 2155

Query: 722  PQ--------PQAAVLSLLGSAQVPQQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQ 772
            PQ        PQ   L+++     P      P       + LL  Q Q Q QQ Q Q Q
Sbjct: 2156 PQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQ 2214



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 69/318 (21%), Positives = 109/318 (34%), Gaps = 58/318 (18%)

Query: 422  MSHS----SSGPASVSQLSSWKTPEQPDPVWVQSS---VSGKGEKHPPPRTQLPSSSGKI 474
            M+HS    S G      +S  + P+ P+ +   ++        +    P+ Q PSSSG +
Sbjct: 747  MNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAM 806

Query: 475  SSGNSFPPQQAG------------SPLKRPFPAAA----PAVAAAAPAPAPAPAAAPALA 518
            S G   PP Q G            +PL    P A+    P V  +   P P PA+  A  
Sbjct: 807  SVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGM 866

Query: 519  AAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGLKATNV 578
             +       G  P     P+ P    S    +   PT      P+      +T  ++T  
Sbjct: 867  PSLQHTTPPGMTPPQPAAPTQPSTPVS---SSGQTPTPTPGSVPS------ATQTQSTPT 917

Query: 579  EGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQF 638
                  AQV      PVQ P    P  +       Q    P+    PG   + + A +  
Sbjct: 918  VQAAAQAQVTPQPQTPVQPPSVATPQSS-------QQQPTPVHAQPPGTPLSQAAASIDN 970

Query: 639  FLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPGPQGSTLGLST 698
             + TP  +           A      QQ    V + +++  T A   +P P         
Sbjct: 971  RVPTPSSV-----------ASAETNSQQPGPDVPVLEMKTETQAEDTEPDP--------G 1011

Query: 699  QGQAFPAQQLLNVNLTGA 716
            + +  P  +++  +L GA
Sbjct: 1012 ESKGEPRSEMMEEDLQGA 1029



 Score = 37.0 bits (84), Expect = 0.074
 Identities = 130/576 (22%), Positives = 179/576 (31%), Gaps = 142/576 (24%)

Query: 356  QSFNDPLLCGKIRPRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSK 415
            Q     L   ++  R+ A   ++  P Q  P   SA   PG+ T         Q   Q +
Sbjct: 1853 QQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSA--PPGTPTQQPSTPQTPQPPAQPQ 1910

Query: 416  VKGPGKMSHSSSGPASV---------------SQLSSWKTPEQPDPVWVQSSVSGKGEKH 460
               P  +S S +G  SV               SQ+ +   P QP P  V+++   + E  
Sbjct: 1911 ---PSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQ 1967

Query: 461  --------------PPPRTQL--PSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAA 504
                          PP RT +  P S     S N   P Q   P+    P+  P     A
Sbjct: 1968 QQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPV---MPSMPPGQWQQA 2024

Query: 505  PAPAPAPAAA---PALAAAAVAAAAGGAAPSHS-----------------QKPSVP---- 540
            P P   P      P ++  A AA AG   PS                   + PS P    
Sbjct: 2025 PLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQ 2084

Query: 541  ----LIKASRRRPAA---GRPTRFVKIAPAIQVRTGSTGLKATNVE-GPVRGAQVLGCSF 592
                ++K++ +  AA    R  ++V   P +Q + G         + G  +   +   + 
Sbjct: 2085 QVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNA 2144

Query: 593  KPVQAPGSGAPAPAGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQ 652
                 P  G P      G GL   G  L    PG     +P          E LR   LQ
Sbjct: 2145 MQAGVPRPGVPPQQQAMG-GLNPQGQALNIMNPG----HNPNMASMNPQYREMLRRQLLQ 2199

Query: 653  VPQGWAVLTGPQQQSHQ--------LVSLQQLQQPTA--AHPP-----QPGPQGSTLGLS 697
              Q        QQQ  Q        +    Q QQP     +PP     Q   Q   L  S
Sbjct: 2200 QQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGS 2259

Query: 698  TQGQ-AFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLP----------F 746
            + GQ A    QL  +   G G+   P  Q A+   +   Q  +Q +  P           
Sbjct: 2260 SMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQH 2319

Query: 747  VLGQQPQ------------------------------------PLLLLQPQPQPQQIQLQ 770
            +L  QPQ                                    P   +QPQP P  +  Q
Sbjct: 2320 MLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQ 2379

Query: 771  TQPLRVLQQPVFLATGAVQIVQPHPGVQAGSQLVGQ 806
            T        P    T A  I Q H G    S ++ Q
Sbjct: 2380 TGS----PHPGLAVTMASSIDQGHLGNPEQSAMLPQ 2411



 Score = 30.4 bits (67), Expect = 6.9
 Identities = 59/222 (26%), Positives = 75/222 (33%), Gaps = 32/222 (14%)

Query: 619 PLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQ 678
           P P A+P  +  + P       N P  L    +QV QG          + QL   Q    
Sbjct: 686 PAPGAQPPVIPQAQPVRPP---NGPLSLPVNRMQVSQGMNSFNPMSLGNVQLP--QAPMG 740

Query: 679 PTAAHPPQPGPQGSTLGLSTQGQAF-PAQQLLNVNLTG-----------AGSGLQPQ--- 723
           P AA P     Q +++G S  G A  P++     N+ G           A S   PQ   
Sbjct: 741 PRAASPMNHSVQMNSMG-SVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQF 799

Query: 724 PQAAVLSLLGSAQVP-QQGVQLPFVLGQQ-PQPLLLLQPQPQPQQIQLQTQ-PLRVLQQP 780
           P ++    +G  Q P Q GV    V G   P PL +L PQ         TQ PL     P
Sbjct: 800 PSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPP 859

Query: 781 VFLATGAVQI--------VQPHPGVQAGSQLVGQRKGGKPTP 814
              A G   +          P P             G  PTP
Sbjct: 860 ASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTP 901


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 93/383 (24%), Positives = 128/383 (33%), Gaps = 73/383 (19%)

Query: 369 PRKKARQKSQKSPWQPFPDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSG 428
           PRK     S+ S  +P P   +A  RP +     R  S++  S  + +  P +   S+ G
Sbjct: 196 PRKSVSSASEHSTTEPSP---AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 252

Query: 429 ----PASVSQ-----LSSWKTPEQPDPVWVQSSVSGKGEKHP--------PPRTQLPSSS 471
               PA  SQ     L + + P+   P    +   G     P        PP    P S 
Sbjct: 253 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSL 312

Query: 472 GKISSGNSFPPQQAG--------------------SPLKRPFPAAAPAVAAAAPAPAPAP 511
             + S  + PP QA                     SPL  P P A PA+A       P+P
Sbjct: 313 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP 372

Query: 512 AAAPALA-----------AAAVAAAAGGAAPSHS-------QKPSVPLIKASRRRPAAGR 553
            A+P L+           A AV       +P  S         P+ P +  S   P+   
Sbjct: 373 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 432

Query: 554 PTRFVKIAPAIQVRTGSTGLKATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGL 613
           P+     AP +QV          +             +  P+Q       AP  ++   L
Sbjct: 433 PS---LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL 489

Query: 614 QSSGGPLPDARPGAVQASSPAPLQFFLNTPEGLRPLTLQVPQGWAVLTGP-QQQSHQLVS 672
           Q+   P P + PG    S  A L         + PL    PQ   VL  P  Q      +
Sbjct: 490 QALPSP-PASFPGQAPFSPSASLP--------MSPLATPPPQAPPVLAAPLLQVPPSPPA 540

Query: 673 LQQLQQPTAAHPPQPGPQGSTLG 695
              LQ P    PP PGP  S  G
Sbjct: 541 SPTLQAP--RRPPTPGPDTSVSG 561



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 107/438 (24%), Positives = 143/438 (32%), Gaps = 55/438 (12%)

Query: 386 PDDHSACLRPGSETDAGRAVSQAQESVQSKVKGPGKMSHSSSGPASVSQLSSWKTPEQPD 445
           P   S   RPG     G  +S  +   + K     K S  S+G     + +S  TP  P 
Sbjct: 108 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAG---ARRDTSGPTPGTPS 164

Query: 446 PVWVQSSVSGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAP 505
           P   + S +   E   P     P+ S +       P      P K    A+  +    +P
Sbjct: 165 PAMARRSRAAGTEVGLPR----PAPSAR-------PRPPTEGPRKSVSSASEHSTTEPSP 213

Query: 506 APAPAPAAAPALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQ 565
           A    P+A   L   A  + +  A P  S   S P  + + R PA           P+  
Sbjct: 214 AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA----------HPSQP 263

Query: 566 VRTGSTGLKATNVEGPVR-GAQVLG-CSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPDA 623
              G   L+   V  P +  A  LG  S  P+  P   AP P+  +   LQ+   P P  
Sbjct: 264 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAP-PSPSAPPSLQTLPSP-PAT 321

Query: 624 RPGAVQASSPAP----LQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQP 679
            P     S  +P       FL +P  L PL    PQ    L  P  Q+            
Sbjct: 322 PPSQATTSLGSPTLQATHSFLPSPP-LSPLATPPPQAPPALALPPLQA------------ 368

Query: 680 TAAHPPQPGPQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQA-AVLSLLGSAQVP 738
               PP P        L+T     P    L V+L  A     P P   A  S   S  V 
Sbjct: 369 ----PPSPPASPPLSPLATPSPQAP--NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 422

Query: 739 QQGVQLPFVLGQQPQPLLLLQPQPQPQQIQLQTQPLRVLQQPVFLATGAVQIVQPHPGVQ 798
                          P L + P P P    +        Q P  LA   +Q+ +P P  Q
Sbjct: 423 PSATPPSQAPPSLAAPPLQVPPSP-PASPPMSPSATPPPQAPPPLAAPPLQLAKPPP--Q 479

Query: 799 AGSQLVGQRKGGKPTPPA 816
           A   L        P+PPA
Sbjct: 480 APPALATPPLQALPSPPA 497



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 92/361 (25%), Positives = 134/361 (37%), Gaps = 52/361 (14%)

Query: 454 SGKGEKHPPPRTQLPSSSGKISSGNSFPPQQAGSPLKRPFPAAAPAVAAAAPAPAPAPAA 513
           SG+GE+ PP +    +S G +SS    P + +G+    P       ++A           
Sbjct: 88  SGRGERAPPAKN---TSPGPVSS----PGRASGTTRPGPLGQKGLRISAEETVARGKATE 140

Query: 514 APALAAAAVAAAAGGAAPSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTGL 573
           AP  +A +  A    + P+    P  P    +RR  AAG      + AP+ + R  + G 
Sbjct: 141 APKRSALSAGARRDTSGPT----PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 196

Query: 574 KATNVEGPVRGAQVLGCSFKPVQAPGSGAPAPAGISGSGLQSSGGPLPD-ARPGAVQASS 632
           + +              + +   + G G   PA  S   L SS  PL   AR G     +
Sbjct: 197 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS---LSSSATPLSSPARSGPSARGT 253

Query: 633 P-APLQFFLNTPEGLRPLTLQVPQGWAVLTGPQQQSHQL---VSLQQLQQPTAAHPPQPG 688
           P AP       P+GL+   L+ PQ    +T P++ +      +S   L  P+ + PP P 
Sbjct: 254 PRAPAHPSQPKPKGLQ--ALRPPQ----VTPPRKDAAPALGPLSSSPLATPSPSAPPSPS 307

Query: 689 PQGSTLGLSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQVPQQGVQLPFVL 748
              S   L +     P+Q         A + L      A  S L S  +       P   
Sbjct: 308 APPSLQTLPSPPATPPSQ---------ATTSLGSPTLQATHSFLPSPPLSPLATPPP--- 355

Query: 749 GQQPQPLLL--LQPQPQPQQIQLQTQPLRVLQQPVFLATG--AVQIVQ------PHPGVQ 798
            Q P  L L  LQ  P P      + PL  L  P   A    AV ++Q      P P VQ
Sbjct: 356 -QAPPALALPPLQAPPSPP----ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 410

Query: 799 A 799
           A
Sbjct: 411 A 411



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 52/209 (24%), Positives = 72/209 (34%), Gaps = 47/209 (22%)

Query: 361 PLLCGKIRPRKKARQKSQKSPWQPFPDDH------SACLRPGSETDAGRAVSQAQESVQS 414
           PLL     P      ++ + P  P PD        +  L PG      R+ S       S
Sbjct: 530 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS-------S 582

Query: 415 KVKGPGKMSHSSSGPASVSQLSSWKTPEQPDPVWVQSSVSGKGEKHPPPRTQLPSSSGKI 474
            + GP    HSSS  ++  +L  +            S   G     PPP  +L +     
Sbjct: 583 TLSGPDLAGHSSSATSTPEELRGY-----------DSGPEGGAAASPPPDAELAACHPAA 631

Query: 475 SSGNSFPPQQ----AGSPLKRPFPAAAPAVA-------------AAAPA-----PAPAPA 512
            S    PP       G+PL  P PA  P  A             +A PA     P P+P 
Sbjct: 632 WSRGPAPPLAFRGAPGAPLPWP-PATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 690

Query: 513 AAPALAAAAVAAAAGGAAPSHSQKPSVPL 541
            +   AAA   A A   +P  ++   +PL
Sbjct: 691 TSGGKAAAGAGAGASSRSPKQARLGELPL 719



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 80/322 (24%), Positives = 108/322 (33%), Gaps = 46/322 (14%)

Query: 484 QAGSPLKRPFPAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAG--------------GA 529
           +AG+  + P  A AP +    P  +P P      AA  V  AAG              G 
Sbjct: 9   KAGAAARTP-AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG 67

Query: 530 APSHSQKPSVPLIKASRRRPAAGRPTRFVKIAPAIQVRTGSTG----LKATNVEGPVRGA 585
           A      P     + S R PA+GR  R     PA     G          T   GP+ G 
Sbjct: 68  ATIPESAPRAGPTRTS-RPPASGRGER---APPAKNTSPGPVSSPGRASGTTRPGPL-GQ 122

Query: 586 QVLGCSFKPVQAPGSGAPAP--AGISGSGLQSSGGPLPDARPGAVQASSPAPLQFFLNTP 643
           + L  S +   A G    AP  + +S    + + GP P     A+   S A       T 
Sbjct: 123 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA-----AGTE 177

Query: 644 EGL-RPLTLQVPQGWAVLTGPQQQSHQLVSLQQLQQPTAAHPPQPG-------PQGSTLG 695
            GL RP     P+      GP ++S    S     +P+ A   +P        P   +L 
Sbjct: 178 VGLPRPAPSARPR--PPTEGP-RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 234

Query: 696 LSTQGQAFPAQQLLNVNLTGAGSGLQPQPQAAVLSLLGSAQV-PQQGVQLPFVLGQQPQP 754
            S    + PA+   +   T        QP+   L  L   QV P +    P +      P
Sbjct: 235 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 294

Query: 755 LLLLQPQPQPQQI---QLQTQP 773
           L    P   P       LQT P
Sbjct: 295 LATPSPSAPPSPSAPPSLQTLP 316


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,194,984
Number of Sequences: 37866
Number of extensions: 2458024
Number of successful extensions: 25742
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 350
Number of HSP's successfully gapped in prelim test: 1377
Number of HSP's that attempted gapping in prelim test: 13983
Number of HSP's gapped (non-prelim): 7211
length of query: 817
length of database: 18,247,518
effective HSP length: 111
effective length of query: 706
effective length of database: 14,044,392
effective search space: 9915340752
effective search space used: 9915340752
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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