BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|209969836 transportin 2 (importin 3, karyopherin beta 2b) isoform 3 [Homo sapiens] (887 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|209969836 transportin 2 (importin 3, karyopherin beta 2b) iso... 1800 0.0 gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isof... 1800 0.0 gi|209969838 transportin 2 (importin 3, karyopherin beta 2b) iso... 1792 0.0 gi|23510381 transportin 1 isoform 2 [Homo sapiens] 1566 0.0 gi|133925811 transportin 1 isoform 1 [Homo sapiens] 1566 0.0 gi|19923142 karyopherin beta 1 [Homo sapiens] 120 6e-27 gi|24797086 importin 5 [Homo sapiens] 67 6e-11 gi|62460637 importin 4 [Homo sapiens] 66 1e-10 gi|45331213 RAN binding protein 6 [Homo sapiens] 65 2e-10 gi|198041777 Ran binding protein 11 isoform 1 [Homo sapiens] 47 6e-05 gi|39725950 Ran binding protein 11 isoform 2 [Homo sapiens] 47 6e-05 gi|21361659 importin 9 [Homo sapiens] 47 6e-05 gi|29029559 CSE1 chromosome segregation 1-like protein [Homo sap... 43 0.001 gi|122937211 KIAA0368 protein [Homo sapiens] 39 0.021 gi|4507943 exportin 1 [Homo sapiens] 38 0.048 gi|4504901 karyopherin alpha 4 [Homo sapiens] 38 0.048 gi|55956788 nucleolin [Homo sapiens] 37 0.062 gi|6912478 karyopherin alpha 6 [Homo sapiens] 37 0.081 gi|4507397 transcription factor 2 [Homo sapiens] 36 0.14 gi|54607053 GCN1 general control of amino-acid synthesis 1-like ... 36 0.14 gi|21361794 TIP120 protein [Homo sapiens] 36 0.18 gi|32455246 beta isoform of regulatory subunit A, protein phosph... 35 0.24 gi|32455244 beta isoform of regulatory subunit A, protein phosph... 35 0.24 gi|27477070 BTAF1 RNA polymerase II, B-TFIID transcription facto... 35 0.24 gi|154350213 hypothetical protein LOC79591 [Homo sapiens] 35 0.40 gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens] 34 0.69 gi|112420977 TBP-interacting protein isoform 2 [Homo sapiens] 34 0.69 gi|89886480 zinedin isoform 2 [Homo sapiens] 34 0.69 gi|89886477 zinedin isoform 1 [Homo sapiens] 34 0.69 gi|54112117 splicing factor 3b, subunit 1 isoform 1 [Homo sapiens] 34 0.69 >gi|209969836 transportin 2 (importin 3, karyopherin beta 2b) isoform 3 [Homo sapiens] Length = 887 Score = 1800 bits (4662), Expect = 0.0 Identities = 887/887 (100%), Positives = 887/887 (100%) Query: 1 MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDE 60 MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDE Sbjct: 1 MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDE 60 Query: 61 PTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGE 120 PTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGE Sbjct: 61 PTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGE 120 Query: 121 LQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQF 180 LQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQF Sbjct: 121 LQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQF 180 Query: 181 FKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVML 240 FKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVML Sbjct: 181 FKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVML 240 Query: 241 LEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIP 300 LEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIP Sbjct: 241 LEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIP 300 Query: 301 ILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAED 360 ILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAED Sbjct: 301 ILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAED 360 Query: 361 DDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA 420 DDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA Sbjct: 361 DDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA 420 Query: 421 IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT 480 IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT Sbjct: 421 IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT 480 Query: 481 ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD 540 ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD Sbjct: 481 ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD 540 Query: 541 AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP 600 AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP Sbjct: 541 AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP 600 Query: 601 YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV 660 YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV Sbjct: 601 YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV 660 Query: 661 ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS 720 ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS Sbjct: 661 ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS 720 Query: 721 VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCP 780 VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCP Sbjct: 721 VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCP 780 Query: 781 QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWV 840 QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWV Sbjct: 781 QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWV 840 Query: 841 SPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV 887 SPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV Sbjct: 841 SPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV 887 >gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isoform 2 [Homo sapiens] Length = 887 Score = 1800 bits (4662), Expect = 0.0 Identities = 887/887 (100%), Positives = 887/887 (100%) Query: 1 MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDE 60 MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDE Sbjct: 1 MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDE 60 Query: 61 PTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGE 120 PTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGE Sbjct: 61 PTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGE 120 Query: 121 LQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQF 180 LQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQF Sbjct: 121 LQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQF 180 Query: 181 FKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVML 240 FKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVML Sbjct: 181 FKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVML 240 Query: 241 LEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIP 300 LEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIP Sbjct: 241 LEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIP 300 Query: 301 ILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAED 360 ILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAED Sbjct: 301 ILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAED 360 Query: 361 DDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA 420 DDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA Sbjct: 361 DDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA 420 Query: 421 IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT 480 IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT Sbjct: 421 IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT 480 Query: 481 ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD 540 ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD Sbjct: 481 ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD 540 Query: 541 AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP 600 AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP Sbjct: 541 AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP 600 Query: 601 YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV 660 YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV Sbjct: 601 YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV 660 Query: 661 ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS 720 ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS Sbjct: 661 ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS 720 Query: 721 VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCP 780 VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCP Sbjct: 721 VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCP 780 Query: 781 QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWV 840 QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWV Sbjct: 781 QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWV 840 Query: 841 SPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV 887 SPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV Sbjct: 841 SPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV 887 >gi|209969838 transportin 2 (importin 3, karyopherin beta 2b) isoform 1 [Homo sapiens] Length = 897 Score = 1792 bits (4641), Expect = 0.0 Identities = 887/897 (98%), Positives = 887/897 (98%), Gaps = 10/897 (1%) Query: 1 MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDE 60 MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDE Sbjct: 1 MDWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDE 60 Query: 61 PTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGE 120 PTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGE Sbjct: 61 PTRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGE 120 Query: 121 LQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQF 180 LQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQF Sbjct: 121 LQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQF 180 Query: 181 FKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVML 240 FKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVML Sbjct: 181 FKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVML 240 Query: 241 LEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIP 300 LEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIP Sbjct: 241 LEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIP 300 Query: 301 ILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAED 360 ILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAED Sbjct: 301 ILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAED 360 Query: 361 DDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA 420 DDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA Sbjct: 361 DDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA 420 Query: 421 IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT 480 IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT Sbjct: 421 IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT 480 Query: 481 ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD 540 ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD Sbjct: 481 ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD 540 Query: 541 AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP 600 AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP Sbjct: 541 AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP 600 Query: 601 YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV 660 YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV Sbjct: 601 YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV 660 Query: 661 ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS 720 ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS Sbjct: 661 ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS 720 Query: 721 VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENT----------AI 770 VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENT AI Sbjct: 721 VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTGRLTSPSAIPAI 780 Query: 771 TIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFI 830 TIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFI Sbjct: 781 TIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFI 840 Query: 831 FFCDAVASWVSPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV 887 FFCDAVASWVSPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV Sbjct: 841 FFCDAVASWVSPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV 897 >gi|23510381 transportin 1 isoform 2 [Homo sapiens] Length = 890 Score = 1566 bits (4055), Expect = 0.0 Identities = 758/887 (85%), Positives = 830/887 (93%), Gaps = 1/887 (0%) Query: 2 DWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDEP 61 +W+PDEQGLQQ+LQLLK+SQSP+T QR VQ KL+QLNQ+PDFNNYLIFVLT+LKSEDEP Sbjct: 4 EWKPDEQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSEDEP 63 Query: 62 TRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGEL 121 TRSLSGLILKNNVKAH+Q+FP V DFIK ECLNNIGD+S LIRAT+GILITTIASKGEL Sbjct: 64 TRSLSGLILKNNVKAHFQNFPNGVTDFIKSECLNNIGDSSPLIRATVGILITTIASKGEL 123 Query: 122 QMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQFF 181 Q WP+LLP+LC+LL+SEDYNTCEGAFGALQKICEDS+E+LDSD L+RPLNIMIPKFLQFF Sbjct: 124 QNWPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPLNIMIPKFLQFF 183 Query: 182 KHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVMLL 241 KH SPKIRSHA+ACVNQFI+ R QALM +ID+FIE+LFALA D++PEVRKNVCRALVMLL Sbjct: 184 KHSSPKIRSHAVACVNQFIISRTQALMLHIDSFIENLFALAGDEEPEVRKNVCRALVMLL 243 Query: 242 EVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIPI 301 EVR+DRL+PHMH+I++YMLQRTQD DENVALEACEFWLTLAEQPICK+VL HL +LIP+ Sbjct: 244 EVRMDRLLPHMHNIVEYMLQRTQDQDENVALEACEFWLTLAEQPICKDVLVRHLPKLIPV 303 Query: 302 LVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAEDD 361 LVNGMKYS+IDIILLKGDVEEDE +PDSEQDI+PRFH+SRTV H+ + + +D +D+ Sbjct: 304 LVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQHDEDGIEEEDDDDDE 363 Query: 362 -DDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA 420 DDDD +SDWNLRKCSAAALDVLANV+R+ELLPH+LPLLK LLFH EWVVKESGILVLGA Sbjct: 364 IDDDDTISDWNLRKCSAAALDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLGA 423 Query: 421 IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT 480 IAEGCMQGM+PYLPELIPHLIQCLSDKKALVRSI CWTLSRYAHWVVSQPPD +LKPLMT Sbjct: 424 IAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMT 483 Query: 481 ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD 540 ELLKRILD NKRVQEAACSAFATLEEEACTELVPYL+YILDTLVFAF KYQHKNLLILYD Sbjct: 484 ELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLILYD 543 Query: 541 AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP 600 AIGTLADSVGHHLN+PEYIQ LMPPLIQKWN LKDEDKDLFPLLECLSSVATALQSGFLP Sbjct: 544 AIGTLADSVGHHLNKPEYIQMLMPPLIQKWNMLKDEDKDLFPLLECLSSVATALQSGFLP 603 Query: 601 YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV 660 YCEPVYQRCV LVQKTLAQAM+ P+QYEAPDKDFMIVALDLLSGLAEGLGG++EQLV Sbjct: 604 YCEPVYQRCVNLVQKTLAQAMLNNAQPDQYEAPDKDFMIVALDLLSGLAEGLGGNIEQLV 663 Query: 661 ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS 720 ARSNI+TL++QCMQD MPEVRQSSFALLGDLTKACF HVKPCIA+FMPILGTNLNPEFIS Sbjct: 664 ARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPEFIS 723 Query: 721 VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCP 780 VCNNATWAIGEI +QMG EMQPY+ MVL+ LVEIINRPNTPKTLLENTAITIGRLGYVCP Sbjct: 724 VCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIINRPNTPKTLLENTAITIGRLGYVCP 783 Query: 781 QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWV 840 QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGIC MI VNP GV+QDFIFFCDAVASW+ Sbjct: 784 QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMISVNPSGVIQDFIFFCDAVASWI 843 Query: 841 SPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV 887 +PKDDLRDMF KILHGFK+QVG++NW++FS+QFP LKERLAAFYGV Sbjct: 844 NPKDDLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAFYGV 890 >gi|133925811 transportin 1 isoform 1 [Homo sapiens] Length = 898 Score = 1566 bits (4055), Expect = 0.0 Identities = 758/887 (85%), Positives = 830/887 (93%), Gaps = 1/887 (0%) Query: 2 DWQPDEQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDEP 61 +W+PDEQGLQQ+LQLLK+SQSP+T QR VQ KL+QLNQ+PDFNNYLIFVLT+LKSEDEP Sbjct: 12 EWKPDEQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSEDEP 71 Query: 62 TRSLSGLILKNNVKAHYQSFPPPVADFIKQECLNNIGDASSLIRATIGILITTIASKGEL 121 TRSLSGLILKNNVKAH+Q+FP V DFIK ECLNNIGD+S LIRAT+GILITTIASKGEL Sbjct: 72 TRSLSGLILKNNVKAHFQNFPNGVTDFIKSECLNNIGDSSPLIRATVGILITTIASKGEL 131 Query: 122 QMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQFF 181 Q WP+LLP+LC+LL+SEDYNTCEGAFGALQKICEDS+E+LDSD L+RPLNIMIPKFLQFF Sbjct: 132 QNWPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPLNIMIPKFLQFF 191 Query: 182 KHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVMLL 241 KH SPKIRSHA+ACVNQFI+ R QALM +ID+FIE+LFALA D++PEVRKNVCRALVMLL Sbjct: 192 KHSSPKIRSHAVACVNQFIISRTQALMLHIDSFIENLFALAGDEEPEVRKNVCRALVMLL 251 Query: 242 EVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIPI 301 EVR+DRL+PHMH+I++YMLQRTQD DENVALEACEFWLTLAEQPICK+VL HL +LIP+ Sbjct: 252 EVRMDRLLPHMHNIVEYMLQRTQDQDENVALEACEFWLTLAEQPICKDVLVRHLPKLIPV 311 Query: 302 LVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAEDD 361 LVNGMKYS+IDIILLKGDVEEDE +PDSEQDI+PRFH+SRTV H+ + + +D +D+ Sbjct: 312 LVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQHDEDGIEEEDDDDDE 371 Query: 362 -DDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA 420 DDDD +SDWNLRKCSAAALDVLANV+R+ELLPH+LPLLK LLFH EWVVKESGILVLGA Sbjct: 372 IDDDDTISDWNLRKCSAAALDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLGA 431 Query: 421 IAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMT 480 IAEGCMQGM+PYLPELIPHLIQCLSDKKALVRSI CWTLSRYAHWVVSQPPD +LKPLMT Sbjct: 432 IAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMT 491 Query: 481 ELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYD 540 ELLKRILD NKRVQEAACSAFATLEEEACTELVPYL+YILDTLVFAF KYQHKNLLILYD Sbjct: 492 ELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLILYD 551 Query: 541 AIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLP 600 AIGTLADSVGHHLN+PEYIQ LMPPLIQKWN LKDEDKDLFPLLECLSSVATALQSGFLP Sbjct: 552 AIGTLADSVGHHLNKPEYIQMLMPPLIQKWNMLKDEDKDLFPLLECLSSVATALQSGFLP 611 Query: 601 YCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLV 660 YCEPVYQRCV LVQKTLAQAM+ P+QYEAPDKDFMIVALDLLSGLAEGLGG++EQLV Sbjct: 612 YCEPVYQRCVNLVQKTLAQAMLNNAQPDQYEAPDKDFMIVALDLLSGLAEGLGGNIEQLV 671 Query: 661 ARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFIS 720 ARSNI+TL++QCMQD MPEVRQSSFALLGDLTKACF HVKPCIA+FMPILGTNLNPEFIS Sbjct: 672 ARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPEFIS 731 Query: 721 VCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCP 780 VCNNATWAIGEI +QMG EMQPY+ MVL+ LVEIINRPNTPKTLLENTAITIGRLGYVCP Sbjct: 732 VCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIINRPNTPKTLLENTAITIGRLGYVCP 791 Query: 781 QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWV 840 QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGIC MI VNP GV+QDFIFFCDAVASW+ Sbjct: 792 QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMISVNPSGVIQDFIFFCDAVASWI 851 Query: 841 SPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFYGV 887 +PKDDLRDMF KILHGFK+QVG++NW++FS+QFP LKERLAAFYGV Sbjct: 852 NPKDDLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAFYGV 898 >gi|19923142 karyopherin beta 1 [Homo sapiens] Length = 876 Score = 120 bits (301), Expect = 6e-27 Identities = 172/794 (21%), Positives = 314/794 (39%), Gaps = 110/794 (13%) Query: 12 QVLQLLKDSQSPNTATQRIVQDKLKQ--LNQFPDFNNYLIFVLTRLKSEDEPTRSLSGLI 69 +++ +L+ + SP+ Q L++ + P F L VL + R +GL Sbjct: 2 ELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLAN-PGNSQVARVAAGLQ 60 Query: 70 LKNN-------VKAHYQ----SFPPPVADFIKQECLNNIGDA----SSLIRATIGILITT 114 +KN+ +KA YQ + +K L +G SS + GI Sbjct: 61 IKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAE 120 Query: 115 IASKGELQMWPELLPQL-CNLLN-SEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNI 172 I + WPEL+PQL N+ N + + E A+ IC+D +D + L N Sbjct: 121 IP----VNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQD----IDPEQLQDKSNE 172 Query: 173 MIPKFLQFFKHCSPKIRSHAIACVNQFIMDRAQALMDNIDTFIEHLFALAVD------DD 226 ++ +Q + P + +A N +++ + N D E F + V D Sbjct: 173 ILTAIIQGMRKEEPS-NNVKLAATNA-LLNSLEFTKANFDKESERHFIMQVVCEATQCPD 230 Query: 227 PEVRKNVCRALVMLLEVRIDRLIPHMH-SIIQYMLQRTQDHDENVALEACEFWLTLAEQP 285 VR + LV ++ + + +M ++ ++ + + VAL+ EFW + ++ Sbjct: 231 TRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDE- 289 Query: 286 ICKEVLASHLVQLIPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTL 345 E+D+ + + E P+ + K L Sbjct: 290 ------------------------EMDLAIEASEAAEQGRPPEHTSKF---YAKGALQYL 322 Query: 346 PHEAERPDGSEDAEDDDDDDALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFH 405 + +D DDDDD WN K + L +LA ++++PH+LP +K + + Sbjct: 323 VPILTQTLTKQDENDDDDD-----WNPCKAAGVCLMLLATCCEDDIVPHVLPFIKEHIKN 377 Query: 406 PEWVVKESGILVLGAIAEGCMQGMV-PYLPELIPHLIQCLSDKKALVRSIACWTLSRYAH 464 P+W +++ ++ G I EG + P + + +P LI+ + D +VR A WT+ R Sbjct: 378 PDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKDPSVVVRDTAAWTVGRICE 437 Query: 465 WVVSQP-PDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTL 523 + D++L PL+ L++ L RV C AF++L EA E + Sbjct: 438 LLPEAAINDVYLAPLLQCLIEG-LSAEPRVASNVCWAFSSL-AEAAYEAADVADDQEEPA 495 Query: 524 VFAFGKYQHKNLLILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPL 583 + LI+ + T GH N + + ++ K+ KD +P Sbjct: 496 TYCLSSSFE---LIVQKLLETTDRPDGHQNNLRSSAYESLMEIV------KNSAKDCYPA 546 Query: 584 LECLSSV-------ATALQSGFLPYCEPV-YQRCVTLVQKTLAQAMMYTQHPEQYEAPDK 635 ++ + V ++S + + + +L+ TL + QH + + D Sbjct: 547 VQKTTLVIMERLQQVLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDALQISDV 606 Query: 636 DFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLL----FQCMQDSMP------------E 679 M L + A G + L+A S ++ +L + M+ P + Sbjct: 607 -VMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLGGEFLKYMEAFKPFLGIGLKNYAEYQ 665 Query: 680 VRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFI--SVCNNATWAIGEICMQMG 737 V ++ L+GDL +A ++ P E M +L NL E + SV G+I + +G Sbjct: 666 VCLAAVGLVGDLCRALQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDIALAIG 725 Query: 738 AEMQPYVQMVLNNL 751 E + Y+++VLN L Sbjct: 726 GEFKKYLEVVLNTL 739 >gi|24797086 importin 5 [Homo sapiens] Length = 1115 Score = 67.4 bits (163), Expect = 6e-11 Identities = 132/616 (21%), Positives = 243/616 (39%), Gaps = 88/616 (14%) Query: 11 QQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSED--EPTRSLSGL 68 QQ LL + SP+ ++ ++ + + + + F+L +++ E R ++ + Sbjct: 27 QQFYLLLGNLLSPDNVVRKQAEETYENIPG----QSKITFLLQAIRNTTAAEEARQMAAV 82 Query: 69 ILKNNVKAH----YQSFPPPVADFIKQECLNNIG--DASSLIRATIGI---LITTIASKG 119 +L+ + + Y + P V IK E L I SS+ + I L + + Sbjct: 83 LLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQSSMRKKVCDIAAELARNLIDED 142 Query: 120 ELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKI--CEDSSELLDSDALNRPLNIMIPKF 177 WPE L L + ++S++ E A + + D + R M+ + Sbjct: 143 GNNQWPEGLKFLFDSVSSQNVGLREAALHIFWNFPGIFGNQQQHYLDVIKR----MLVQC 198 Query: 178 LQFFKHCSPKIRSHAIACVNQFIM--DRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCR 235 +Q +H P IR+ + FI+ + AL + + D + +V + Sbjct: 199 MQDQEH--PSIRTLSARATAAFILANEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLK 256 Query: 236 ALVMLLEVRIDRLIPHMHSIIQYMLQRTQDHDENVALE--ACEFWLTLAEQPICKEVLAS 293 +LV + + L PH+ + +Q L+ D N A E +TL+E +L Sbjct: 257 SLVEIADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQRQLALEVIVTLSETAAA--MLRK 314 Query: 294 H---LVQLIPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAE 350 H + Q IP ++ + D+EEDE + Sbjct: 315 HTNIVAQTIP-----------QMLAMMVDLEEDE-------------------------D 338 Query: 351 RPDGSEDAEDDDDDDALSDWNLRKCSAAALDVLANVFREEL-LPHLLPLLKGLLFHPEWV 409 + E +DD D +A++ +ALD +A +L LP + + +L +P+W Sbjct: 339 WANADELEDDDFDSNAVA-------GESALDRMACGLGGKLVLPMIKEHIMQMLQNPDWK 391 Query: 410 VKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQ 469 + +G++ L AI EGC Q M L E++ ++ L D VR AC + + A Sbjct: 392 YRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFAPG 451 Query: 470 PPDMHLKPLMTELLKRILD-GNKRVQEAACSAFATLEEEACTE--LVPYL----SYILDT 522 + ++ LL+ + D GN+RVQ A +A E+ C + L+PYL ++ Sbjct: 452 FQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTED-CPKSLLIPYLDNLVKHLHSI 510 Query: 523 LVFAFGKYQHKNLLILYDAIGTLADSVGHHLNQP--EYIQKLMPPLIQKWNELKDEDKDL 580 +V + K ++ + + T SV + Y MP L ++ L Sbjct: 511 MVLKLQELIQKGTKLVLEQVVTSIASVADTAEEKFVPYYDLFMPSLKHIVENAVQKELRL 570 Query: 581 F--PLLECLSSVATAL 594 +EC+S + A+ Sbjct: 571 LRGKTIECISLIGLAV 586 >gi|62460637 importin 4 [Homo sapiens] Length = 1081 Score = 66.2 bits (160), Expect = 1e-10 Identities = 102/438 (23%), Positives = 185/438 (42%), Gaps = 55/438 (12%) Query: 349 AERPDGSEDAEDDDDDDALSDWNL-----RKCSAAALDVLA-NVFREELLPHLLPLLKGL 402 AE P G D ED D ++ + L + + +D+LA ++ E+L P L+P+L+ Sbjct: 301 AEPPPGQLDPEDQDSEEEELEIELMGETPKHFAVQVVDMLALHLPPEKLCPQLMPMLEEA 360 Query: 403 LFHPEWVVKESGILVLGAIAEGCMQGMVP-YLPELIPHLIQCLSDKKALVRSIACWTLSR 461 L +++G+LVL +++G + LP L+ + + L D +VR+ A + L + Sbjct: 361 LRSESPYQRKAGLLVLAVLSDGAGDHIRQRLLPPLLQIVCKGLEDPSQVVRNAALFALGQ 420 Query: 462 YAHWVVSQPP----DMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLS 517 ++ + QP + PL+ LK + G+ AC A E ++ PYL Sbjct: 421 FSENL--QPHISSYSREVMPLLLAYLKSVPLGHTHHLAKACYALENFVENLGPKVQPYLP 478 Query: 518 YILDTLVFAF---GKYQHKNLLILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNE-L 573 +++ ++ + K L + A+G +A + L P +++ E L Sbjct: 479 ELMECMLQLLRNPSSPRAKELAV--SALGAIATAAQASL------LPYFPAIMEHLREFL 530 Query: 574 KDEDKDLFPL----LECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQ 629 +DL P+ LE L +A A+ P E Q + L +Q Sbjct: 531 LTGREDLQPVQIQSLETLGVLARAVGEPMRPLAEECCQLGLGLC--------------DQ 576 Query: 630 YEAPDKDFMIVAL-DLLSGL-AEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFAL 687 + PD +L LSGL EGL H+EQ+ + +M L + + +P+ SS L Sbjct: 577 VDDPDLRRCTYSLFAALSGLMGEGLAPHLEQI---TTLMLLSLRSTEGIVPQYDGSSSFL 633 Query: 688 LGDLTKACFIHVKPCIAEFMP------ILGTNLNPEFISVCNNATWAIGEICMQMGAEMQ 741 L D ++ + + E + I G ++ F + A+GEI + Sbjct: 634 LFD-DESDGEEEEELMDEDVEEEDDSEISGYSVENAFFDEKEDTCAAVGEISVNTSVAFL 692 Query: 742 PYVQMVLNNLVEIINRPN 759 PY++ V + +++ P+ Sbjct: 693 PYMESVFEEVFKLLECPH 710 Score = 53.9 bits (128), Expect = 6e-07 Identities = 90/443 (20%), Positives = 186/443 (41%), Gaps = 48/443 (10%) Query: 376 SAAALDVLANVFREELL---PHLLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMVPY 432 S + + A +FR+E L P LL LL+ P +E G+L+L + + P+ Sbjct: 97 SLSLAQLSATIFRKEGLEAWPQLLQLLQHSTHSPHSPEREMGLLLLSVVVTSRPEAFQPH 156 Query: 433 LPELIPHLIQCLSDKKA---LVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDG 489 EL+ L + L + + L S+ TL+ A ++ ++ D+ L ++ L + Sbjct: 157 HRELLRLLNETLGEVGSPGLLFYSLR--TLTTMAPYLSTE--DVPLARMLVPKLIMAMQT 212 Query: 490 NKRVQEA-ACSAFATLEEEACTE---LVPYLSYILDTLV-----FAFGK-YQHKNLLILY 539 + EA AC A L+E +E + PYLS +L + A G + + L L Sbjct: 213 LIPIDEAKACEALEALDELLESEVPVITPYLSEVLTFCLEVARNVALGNAIRIRILCCLT 272 Query: 540 DAIGTLADSVGHHLNQPEYIQKLMP---------PLIQKWNELKDEDKDLFPLLECLSSV 590 + + ++ + P + L P L + + ++E+ ++ + E Sbjct: 273 FLVKVKSKALLKNRLLPPLLHTLFPIVAAEPPPGQLDPEDQDSEEEELEIELMGETPKHF 332 Query: 591 ATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAE 650 A + + P +K Q M + + E+P + L +L+ L++ Sbjct: 333 AVQVVDMLALHLPP---------EKLCPQLMPMLEEALRSESPYQ--RKAGLLVLAVLSD 381 Query: 651 GLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPIL 710 G G H+ Q + ++ ++ + ++D VR ++ LG ++ H+ E MP+L Sbjct: 382 GAGDHIRQRLL-PPLLQIVCKGLEDPSQVVRNAALFALGQFSENLQPHISSYSREVMPLL 440 Query: 711 GTNLNPEFISVCNN---ATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLEN 767 L + ++ A +A+ +G ++QPY+ ++ +++++ P++P+ Sbjct: 441 LAYLKSVPLGHTHHLAKACYALENFVENLGPKVQPYLPELMECMLQLLRNPSSPRA---- 496 Query: 768 TAITIGRLGYVCPQEVAPMLQQF 790 + + LG + A +L F Sbjct: 497 KELAVSALGAIATAAQASLLPYF 519 >gi|45331213 RAN binding protein 6 [Homo sapiens] Length = 1105 Score = 65.5 bits (158), Expect = 2e-10 Identities = 76/281 (27%), Positives = 124/281 (44%), Gaps = 49/281 (17%) Query: 343 VTLPHEAERPDGSEDAEDDDDDDALSDWNLRKCSAAALDVLA-NVFREELLPHLLPLLKG 401 V L + + + E EDD D +A++ + +ALD LA + + +LP + Sbjct: 321 VDLQDDEDWVNADEMEEDDFDSNAVA-------AESALDRLACGLGGKVVLPMTKEHIMQ 373 Query: 402 LLFHPEWVVKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSR 461 +L P+W + +G++ L AI EGC Q M L E + ++ L D VR+ AC TL + Sbjct: 374 MLQSPDWKYRHAGLMALSAIGEGCHQQMESILDETVNSVLLFLQDPHPRVRAAACTTLGQ 433 Query: 462 YAHWVVSQPPDMHLKPLMTELLKRILD-GNKRVQEAACSAFATLEEEACTELVPYLSYIL 520 A + ++ LL+ + + GN+RVQ A SA E+ Sbjct: 434 MATDFAPNFQKKFHETVIAALLRTMENQGNQRVQSHAASALIIFIEDC------------ 481 Query: 521 DTLVFAFGKYQHKNLLILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDL 580 K+LL+LY DS+ +L+ I+ + LI+ +L E Sbjct: 482 -----------PKSLLVLY------VDSMVKNLHSVLVIK--LQELIRNGTKLALEQ--- 519 Query: 581 FPLLECLSSVATALQSGFLPYCE---PVYQRCVTL-VQKTL 617 L+ ++SVA ++ F+PY + P + V L VQK L Sbjct: 520 --LVTTIASVADTIEEKFVPYYDIFMPSLKHIVELAVQKEL 558 Score = 32.7 bits (73), Expect = 1.5 Identities = 39/189 (20%), Positives = 74/189 (39%), Gaps = 23/189 (12%) Query: 95 NNIGDASSLIRATIGILITTIASKGELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKIC 154 N + S+L R G+ G + P + +L S D+ AL I Sbjct: 343 NAVAAESALDRLACGL--------GGKVVLPMTKEHIMQMLQSPDWKYRHAGLMALSAIG 394 Query: 155 EDSSELLDSDALNRPLNIMIPKFLQFFKHCSPKIRSHAIACVNQFIMDRAQALMDNI-DT 213 E + ++S L+ + L F + P++R+ A + Q D A +T Sbjct: 395 EGCHQQMESI-----LDETVNSVLLFLQDPHPRVRAAACTTLGQMATDFAPNFQKKFHET 449 Query: 214 FIEHLF-ALAVDDDPEVRKNVCRALVMLLE--------VRIDRLIPHMHSIIQYMLQRTQ 264 I L + + V+ + AL++ +E + +D ++ ++HS++ LQ Sbjct: 450 VIAALLRTMENQGNQRVQSHAASALIIFIEDCPKSLLVLYVDSMVKNLHSVLVIKLQELI 509 Query: 265 DHDENVALE 273 + +ALE Sbjct: 510 RNGTKLALE 518 Score = 30.0 bits (66), Expect = 9.9 Identities = 18/64 (28%), Positives = 31/64 (48%), Gaps = 2/64 (3%) Query: 628 EQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFAL 687 + ++PD + L LS + EG +E ++ + LLF +QD P VR ++ Sbjct: 373 QMLQSPDWKYRHAGLMALSAIGEGCHQQMESILDETVNSVLLF--LQDPHPRVRAAACTT 430 Query: 688 LGDL 691 LG + Sbjct: 431 LGQM 434 >gi|198041777 Ran binding protein 11 isoform 1 [Homo sapiens] Length = 1015 Score = 47.4 bits (111), Expect = 6e-05 Identities = 33/132 (25%), Positives = 61/132 (46%), Gaps = 6/132 (4%) Query: 13 VLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDEPTRSLSGLILKN 72 VLQ+L + S +TA + +++LKQ P F + L+ + T + D R L+ L K+ Sbjct: 50 VLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTN-HTLDINVRWLAVLYFKH 108 Query: 73 NVKAHYQSFPPPVAD-----FIKQECLNNIGDASSLIRATIGILITTIASKGELQMWPEL 127 + +++ P ++ + N + + I I +LI +A + WPEL Sbjct: 109 GIDRYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPEL 168 Query: 128 LPQLCNLLNSED 139 +P L + +D Sbjct: 169 IPTLIESVKVQD 180 >gi|39725950 Ran binding protein 11 isoform 2 [Homo sapiens] Length = 975 Score = 47.4 bits (111), Expect = 6e-05 Identities = 33/132 (25%), Positives = 61/132 (46%), Gaps = 6/132 (4%) Query: 13 VLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDEPTRSLSGLILKN 72 VLQ+L + S +TA + +++LKQ P F + L+ + T + D R L+ L K+ Sbjct: 10 VLQVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTN-HTLDINVRWLAVLYFKH 68 Query: 73 NVKAHYQSFPPPVAD-----FIKQECLNNIGDASSLIRATIGILITTIASKGELQMWPEL 127 + +++ P ++ + N + + I I +LI +A + WPEL Sbjct: 69 GIDRYWRRVAPHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPEL 128 Query: 128 LPQLCNLLNSED 139 +P L + +D Sbjct: 129 IPTLIESVKVQD 140 >gi|21361659 importin 9 [Homo sapiens] Length = 1041 Score = 47.4 bits (111), Expect = 6e-05 Identities = 43/165 (26%), Positives = 75/165 (45%), Gaps = 11/165 (6%) Query: 5 PDEQGLQQVL-QLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSEDEPTR 63 P QGL++ L L SP + ++++K L +F +L LT R Sbjct: 16 PVAQGLKEALVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHLA-ELTVDPQGALAIR 74 Query: 64 SLSGLILKNNVKAHY----QSFPPPV----ADFIKQECL-NNIGDASSLIRATIGILITT 114 L+ +ILK V+ H+ + F PP A + +E L N + ++ S +R+++ ++ Sbjct: 75 QLASVILKQYVETHWCAQSEKFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSA 134 Query: 115 IASKGELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSE 159 IA + WP+L L +L S D N GA L + + ++ Sbjct: 135 IAHWDWPEAWPQLFNLLMEMLVSGDLNAVHGAMRVLTEFTREVTD 179 >gi|29029559 CSE1 chromosome segregation 1-like protein [Homo sapiens] Length = 971 Score = 43.1 bits (100), Expect = 0.001 Identities = 38/179 (21%), Positives = 77/179 (43%), Gaps = 11/179 (6%) Query: 7 EQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRL-KSEDEPTRSL 65 + LQ + + LK + P+ A +R + K L NY + +LT L KS+D + Sbjct: 5 DANLQTLTEYLKKTLDPDPAIRRPAE---KFLESVEGNQNYPLLLLTLLEKSQDNVIKVC 61 Query: 66 SGLILKNNVKAHY---QSFPPPVADF----IKQECLNNIGDASSLIRATIGILITTIASK 118 + + KN +K ++ + P + + IK ++ + + I+ + I+ I + Sbjct: 62 ASVTFKNYIKRNWRIVEDEPNKICEADRVAIKANIVHLMLSSPEQIQKQLSDAISIIGRE 121 Query: 119 GELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKF 177 Q WP+LL ++ N S D++ G + + S+ L + +++ F Sbjct: 122 DFPQKWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAF 180 >gi|122937211 KIAA0368 protein [Homo sapiens] Length = 2017 Score = 38.9 bits (89), Expect = 0.021 Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 12/144 (8%) Query: 370 WNLRKCSAAALDVLANVFREEL---LPHLLPLLKGLLFHPEWVVKESGILVLGAIAEGCM 426 WN RK +A +V+A E+L LP L+P L F P ++++ + A+ Sbjct: 1267 WNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQAMTSIWNALVTD-- 1324 Query: 427 QGMV-PYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPD--MHLKPLMTELL 483 + MV YL E++ L++ L+ VR +C L+ +P D + P + E L Sbjct: 1325 KSMVDKYLKEILQDLVKNLTSNMWRVRESSCLALNDLLR---GRPLDDIIDKLPEIWETL 1381 Query: 484 KRILDGNKR-VQEAACSAFATLEE 506 R+ D K V++AA A TL + Sbjct: 1382 FRVQDDIKESVRKAAELALKTLSK 1405 Score = 37.7 bits (86), Expect = 0.048 Identities = 29/120 (24%), Positives = 51/120 (42%), Gaps = 3/120 (2%) Query: 405 HPEWVVKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAH 464 H W ++ IA + + P+LP+L+P L + D +R T A Sbjct: 1264 HAMWNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQ--AMTSIWNAL 1321 Query: 465 WVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAF-ATLEEEACTELVPYLSYILDTL 523 D +LK ++ +L+K + RV+E++C A L +++ L I +TL Sbjct: 1322 VTDKSMVDKYLKEILQDLVKNLTSNMWRVRESSCLALNDLLRGRPLDDIIDKLPEIWETL 1381 Score = 36.2 bits (82), Expect = 0.14 Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 5/118 (4%) Query: 392 LPHLLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCL-----SD 446 L L+ + + L W +K G + + +IA+ + PYL ++ L+Q L + Sbjct: 1697 LQELITITQKALQSQSWKMKAQGAIAMASIAKQTSSLVPPYLGMILTALLQGLAGRTWAG 1756 Query: 447 KKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATL 504 K+ L+++IAC + A S P ++ +LK N + + A S A + Sbjct: 1757 KEELLKAIACVVTACSAELEKSVPNQPSTNEILQAVLKECSKENVKYKIVAISCAADI 1814 >gi|4507943 exportin 1 [Homo sapiens] Length = 1071 Score = 37.7 bits (86), Expect = 0.048 Identities = 30/141 (21%), Positives = 61/141 (43%), Gaps = 20/141 (14%) Query: 446 DKKALVRSIACWTLSRY-----AHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSA 500 D KA++ S + + +Y AHW LK ++ +L + + + + VQ+ AC Sbjct: 535 DNKAIIASNIMYIVGQYPRFLRAHW-------KFLKTVVNKLFEFMHETHDGVQDMACDT 587 Query: 501 FATLEEEA--------CTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLADSVGHH 552 F + ++ E++P++ IL+ + Q + + Y+A+G + + Sbjct: 588 FIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQ 647 Query: 553 LNQPEYIQKLMPPLIQKWNEL 573 Q I+K M Q W+ + Sbjct: 648 TVQEHLIEKYMLLPNQVWDSI 668 >gi|4504901 karyopherin alpha 4 [Homo sapiens] Length = 521 Score = 37.7 bits (86), Expect = 0.048 Identities = 55/227 (24%), Positives = 93/227 (40%), Gaps = 27/227 (11%) Query: 370 WNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGAIAEGC-MQG 428 W L + A + + V ++PHL+PLL H E V+ + + +G I G Q Sbjct: 264 WALSYLTDAGNEQIQMVIDSGIVPHLVPLLS----HQEVKVQTAALRAVGNIVTGTDEQT 319 Query: 429 MVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYA---HWVVSQPPDMHLKPLMTELLKR 485 V + + H L+ K + A W LS V D +L P++ LL + Sbjct: 320 QVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDK 379 Query: 486 ILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDA--IG 543 G+ Q+ A A + L + V YL I ++ F NLL + DA + Sbjct: 380 ---GDFGTQKEAAWAISNLTISGRKDQVAYL--IQQNVIPPF-----CNLLTVKDAQVVQ 429 Query: 544 TLADSVGHHLNQPEYIQKLMPPLIQKWNELK-------DEDKDLFPL 583 + D + + L E + + LI++ L+ E++D++ L Sbjct: 430 VVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHENEDIYKL 476 Score = 31.6 bits (70), Expect = 3.4 Identities = 31/144 (21%), Positives = 64/144 (44%), Gaps = 7/144 (4%) Query: 662 RSNIMTLLFQCMQ-DSMPEVRQSSFALLGDLTKACFIHVKPCI-AEFMPILGTNLNPEFI 719 +S I+ +L C++ D P ++ + L ++ + + + +P+ L+ Sbjct: 112 KSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQ 171 Query: 720 SVCNNATWAIGEICMQMGAEMQPYVQM--VLNNLVEIINRPNTPKTLLEN-TAITIGRLG 776 +VC A WA+G I + G + + YV V+ L+ I+ P+ P T L N T + + Sbjct: 172 NVCEQAVWALGNI-IGDGPQCRDYVISLGVVKPLLSFIS-PSIPITFLRNVTWVMVNLCR 229 Query: 777 YVCPQEVAPMLQQFIRPWCTSLRN 800 + P +Q+ + C + + Sbjct: 230 HKDPPPPMETIQEILPALCVLIHH 253 >gi|55956788 nucleolin [Homo sapiens] Length = 710 Score = 37.4 bits (85), Expect = 0.062 Identities = 18/47 (38%), Positives = 25/47 (53%) Query: 319 DVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAEDDDDDD 365 D E+DE + E +I+P K+ E E + ED EDDDDD+ Sbjct: 156 DEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDE 202 >gi|6912478 karyopherin alpha 6 [Homo sapiens] Length = 536 Score = 37.0 bits (84), Expect = 0.081 Identities = 39/160 (24%), Positives = 64/160 (40%), Gaps = 13/160 (8%) Query: 363 DDDALSD--WNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGA 420 D D L+D W L S + + V + L+ LL H ++ V + +G Sbjct: 265 DSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELL----MHNDYKVASPALRAVGN 320 Query: 421 IAEGC-MQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYA---HWVVSQPPDMHLK 476 I G +Q V +P L+ LS K +R ACWT+S + D ++ Sbjct: 321 IVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIF 380 Query: 477 PLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYL 516 P++ E+L++ R ++ A A E + YL Sbjct: 381 PVLIEILQK---AEFRTRKEAAWAITNATSGGTPEQIRYL 417 >gi|4507397 transcription factor 2 [Homo sapiens] Length = 557 Score = 36.2 bits (82), Expect = 0.14 Identities = 29/90 (32%), Positives = 38/90 (42%), Gaps = 13/90 (14%) Query: 276 EFWLTLAEQPICKEVLASHLVQLIPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKP 335 E L + KEVL L +L+P G+K + + G +E D KP Sbjct: 11 ELLSALLSSGVTKEVLVQALEELLPSPNFGVKLETLPLSPGSG----------AEPDTKP 60 Query: 336 RFHKSRTVTLPHEAERPDGSEDAEDDDDDD 365 FH T+T H R G E +ED DD D Sbjct: 61 VFH---TLTNGHAKGRLSGDEGSEDGDDYD 87 >gi|54607053 GCN1 general control of amino-acid synthesis 1-like 1 [Homo sapiens] Length = 2671 Score = 36.2 bits (82), Expect = 0.14 Identities = 31/121 (25%), Positives = 51/121 (42%), Gaps = 8/121 (6%) Query: 379 ALDVLANVFREELLPH----LLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMVPYLP 434 A D A L H +LP L L W K + +LGA+A + + LP Sbjct: 1478 AADDCAKAVMSNLSAHGVKLVLPSLLAALEEESWRTKAGSVELLGAMAYCAPKQLSSCLP 1537 Query: 435 ELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQ 494 ++P L + L+D V+ L R V+ P + + P+ LL + D +++ Q Sbjct: 1538 NIVPKLTEVLTDSHVKVQKAGQQAL-RQIGSVIRNPEILAIAPV---LLDALTDPSRKTQ 1593 Query: 495 E 495 + Sbjct: 1594 K 1594 Score = 31.2 bits (69), Expect = 4.5 Identities = 35/145 (24%), Positives = 61/145 (42%), Gaps = 7/145 (4%) Query: 373 RKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMVPY 432 R +A L L E++LP ++P+L+ L + ++ + L I + + V Y Sbjct: 1942 RTIAARTLGDLVRKLGEKILPEIIPILEEGLRSQKSDERQGVCIGLSEIMKSTSRDAVLY 2001 Query: 433 LPE-LIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNK 491 E L+P + L D VR A T + + Q L+ ++ LLK++ D + Sbjct: 2002 FSESLVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQA----LEDILPFLLKQLDD--E 2055 Query: 492 RVQEAACSAFATLEEEACTELVPYL 516 V E A + ++PYL Sbjct: 2056 EVSEFALDGLKQVMAIKSRVVLPYL 2080 >gi|21361794 TIP120 protein [Homo sapiens] Length = 1230 Score = 35.8 bits (81), Expect = 0.18 Identities = 41/207 (19%), Positives = 82/207 (39%), Gaps = 29/207 (14%) Query: 188 IRSHAIACVNQFIMDRAQALMDNIDTFIEHLFA-LAVDDDPEVRKNVCRALVMLLEVRID 246 +R I + +M + ++ IEHL + L+ +D + + + + Sbjct: 191 VRKRTIIALGHLVMSCGNIVFVDL---IEHLLSELSKNDSMSTTRTYIQCIAAISRQAGH 247 Query: 247 RLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIPILVNGM 306 R+ ++ II +++ D+ + + + + + C + + H+ +I I + Sbjct: 248 RIGEYLEKIIPLVVKFCNVDDDELREYCIQAFESFVRR--CPKEVYPHVSTIINIC---L 302 Query: 307 KYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAEDDDDDDA 366 KY D D +EDE D++ + GS+D DDDD Sbjct: 303 KYLTYDPNYNYDDEDEDENAMDADGG----------------DDDDQGSDDEYSDDDD-- 344 Query: 367 LSDWNLRKCSAAALDVLANVFREELLP 393 W +R+ +A LD + + R E+LP Sbjct: 345 -MSWKVRRAAAKCLDAVVST-RHEMLP 369 Score = 30.8 bits (68), Expect = 5.8 Identities = 38/191 (19%), Positives = 71/191 (37%), Gaps = 28/191 (14%) Query: 127 LLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQFFKHCSP 186 LLP+L L S A++ D + +D N I FL+ + Sbjct: 966 LLPRLKGYLISGSSYARSSVVTAVKFTISDHPQPIDPLLKN-----CIGDFLKTLEDPDL 1020 Query: 187 KIRSHAIACVNQFIMDRAQALMDNIDTFIEHL------------------FALAVDDDPE 228 +R A+ N ++ + D +DT + HL F VDD + Sbjct: 1021 NVRRVALVTFNSAAHNKPSLIRDLLDTVLPHLYNETKVRKELIREVEMGPFKHTVDDGLD 1080 Query: 229 VRKNVCRALVMLLEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICK 288 +RK + LL+ +DRL + + ++ +DH + ++ F + + +C Sbjct: 1081 IRKAAFECMYTLLDSCLDRL--DIFEFLNHVEDGLKDHYD---IKMLTFLMLVRLSTLCP 1135 Query: 289 EVLASHLVQLI 299 + L +L+ Sbjct: 1136 SAVLQRLDRLV 1146 >gi|32455246 beta isoform of regulatory subunit A, protein phosphatase 2 isoform a [Homo sapiens] Length = 601 Score = 35.4 bits (80), Expect = 0.24 Identities = 63/285 (22%), Positives = 116/285 (40%), Gaps = 56/285 (19%) Query: 16 LLKDSQSPNTATQRIVQDK----LKQLNQFPD---FNNYLIFVLTRLKSEDEPTRSLS-- 66 LL ++ T + +V+DK L+Q++Q Y + ++ RL S D T S Sbjct: 101 LLPPLENLATVEETVVRDKAVESLRQISQEHTPVALEAYFVPLVKRLASGDWFTSRTSAC 160 Query: 67 GLI----------LKNNVKAHYQSFPPPVADFIKQECLNNIGDASSL-----IRATIGIL 111 GL +K ++ ++S +++ + +G+ + + +++ I L Sbjct: 161 GLFSVCYPRASNAVKAEIRQQFRSLCSDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPL 220 Query: 112 ITTIASKGELQ---MWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSS---------- 158 T++AS + + E + LL+ +D T L++ ED S Sbjct: 221 FTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETL--VMPTLRQAAEDKSWRVRYMVADR 278 Query: 159 --ELLDSDALNRPLNIMIPKFLQFFKHCSPKIRSHAIACVNQF-----IMDRAQALMDNI 211 EL + LN +IP F K C ++R+ A V + I DR +M+ I Sbjct: 279 FSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKELGENLPIEDRETIIMNQI 338 Query: 212 DTFIEHLFALAVDDDPEVRKNVCRALVMLL------EVRIDRLIP 250 +I+ L V D + K+ +++M L E I+ L+P Sbjct: 339 LPYIKEL----VSDTNQHVKSALASVIMGLSTILGKENTIEHLLP 379 >gi|32455244 beta isoform of regulatory subunit A, protein phosphatase 2 isoform b [Homo sapiens] Length = 667 Score = 35.4 bits (80), Expect = 0.24 Identities = 63/285 (22%), Positives = 116/285 (40%), Gaps = 56/285 (19%) Query: 16 LLKDSQSPNTATQRIVQDK----LKQLNQFPD---FNNYLIFVLTRLKSEDEPTRSLS-- 66 LL ++ T + +V+DK L+Q++Q Y + ++ RL S D T S Sbjct: 101 LLPPLENLATVEETVVRDKAVESLRQISQEHTPVALEAYFVPLVKRLASGDWFTSRTSAC 160 Query: 67 GLI----------LKNNVKAHYQSFPPPVADFIKQECLNNIGDASSL-----IRATIGIL 111 GL +K ++ ++S +++ + +G+ + + +++ I L Sbjct: 161 GLFSVCYPRASNAVKAEIRQQFRSLCSDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPL 220 Query: 112 ITTIASKGELQ---MWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSS---------- 158 T++AS + + E + LL+ +D T L++ ED S Sbjct: 221 FTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETL--VMPTLRQAAEDKSWRVRYMVADR 278 Query: 159 --ELLDSDALNRPLNIMIPKFLQFFKHCSPKIRSHAIACVNQF-----IMDRAQALMDNI 211 EL + LN +IP F K C ++R+ A V + I DR +M+ I Sbjct: 279 FSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKELGENLPIEDRETIIMNQI 338 Query: 212 DTFIEHLFALAVDDDPEVRKNVCRALVMLL------EVRIDRLIP 250 +I+ L V D + K+ +++M L E I+ L+P Sbjct: 339 LPYIKEL----VSDTNQHVKSALASVIMGLSTILGKENTIEHLLP 379 >gi|27477070 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa [Homo sapiens] Length = 1849 Score = 35.4 bits (80), Expect = 0.24 Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 17/117 (14%) Query: 385 NVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCL 444 N+F E++LP L + + V +E I L + E G+VPY+ L+ ++ + Sbjct: 1143 NIFLEKVLPWLGAI-------DDSVKQEGAIEALACVMEQLDVGIVPYIVLLVVPVLGRM 1195 Query: 445 SDKKALVRSIACWTLSRYAHWV-----VSQPPDM-----HLKPLMTELLKRILDGNK 491 SD+ VR +A + + + PP+M LK L+++LDG K Sbjct: 1196 SDQTDSVRFMATQCFATLIRLMPLEAGIPDPPNMSAELIQLKAKERHFLEQLLDGKK 1252 Score = 33.9 bits (76), Expect = 0.69 Identities = 30/132 (22%), Positives = 63/132 (47%), Gaps = 7/132 (5%) Query: 152 KICEDSSELLDSDALNRPLNIM-IPKFLQFFKHCSPKIRSHAIACVNQFIMDRAQALMDN 210 ++ E ++ +DS+ PL + +P ++ S +R A CV +M + A M+ Sbjct: 1087 QVFETAAASMDSEL--HPLLVQHLPHLYMCLQYPSTAVRHMAARCVG--VMSKI-ATMET 1141 Query: 211 IDTFIEHLFA-LAVDDDPEVRKNVCRALVMLLEVRIDRLIPHMHSIIQYMLQRTQDHDEN 269 ++ F+E + L DD ++ AL ++E ++P++ ++ +L R D ++ Sbjct: 1142 MNIFLEKVLPWLGAIDDSVKQEGAIEALACVMEQLDVGIVPYIVLLVVPVLGRMSDQTDS 1201 Query: 270 VALEACEFWLTL 281 V A + + TL Sbjct: 1202 VRFMATQCFATL 1213 Score = 30.4 bits (67), Expect = 7.6 Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 3/86 (3%) Query: 431 PYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGN 490 P L + +PHL CL VR +A + + + ++ L+ ++ L I D Sbjct: 1102 PLLVQHLPHLYMCLQYPSTAVRHMAARCVGVMSKIATMETMNIFLEKVL-PWLGAIDDSV 1160 Query: 491 KRVQEAACSAFATLEEEACTELVPYL 516 K QE A A A + E+ +VPY+ Sbjct: 1161 K--QEGAIEALACVMEQLDVGIVPYI 1184 >gi|154350213 hypothetical protein LOC79591 [Homo sapiens] Length = 689 Score = 34.7 bits (78), Expect = 0.40 Identities = 31/124 (25%), Positives = 58/124 (46%), Gaps = 15/124 (12%) Query: 202 DRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCRALVMLLEVRIDRLIPHMHSIIQYMLQ 261 D+A+ M N+ +E L +L + E K++C L++ L D + ++I++Y++ Sbjct: 131 DKAELCMKNL---MESLDSLLCAEGSESLKSLCLKLLLCLVTVTDNI--SQNTILEYVMI 185 Query: 262 RTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIPILVNGMKYSEIDIILLKGDVE 321 N EA L + P + V L+ +LVN KY ++ ++K + Sbjct: 186 -------NSIFEAI---LQILSHPPSRREHGYDAVVLLALLVNYRKYESVNPYIVKLSIV 235 Query: 322 EDEA 325 +DEA Sbjct: 236 DDEA 239 >gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens] Length = 1236 Score = 33.9 bits (76), Expect = 0.69 Identities = 40/165 (24%), Positives = 69/165 (41%), Gaps = 24/165 (14%) Query: 380 LDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMV--------- 430 L LA V L H+ L+ G++F + S + A +QG++ Sbjct: 460 LTELAGVLPGSLAEHMPVLVSGIIFS---LADRSSSSTIRMDALAFLQGLLGTEPAEAFH 516 Query: 431 PYLPELIPHLIQCLSDKKALVRSIACWTLSRY--AHWVVSQPPDMHLKPLMTELLK---- 484 P+LP L+P ++ C++D + + A L A W + +P + +P + E+ Sbjct: 517 PHLPILLPPVMACVADSFYKIAAEALVVLQELVRALWPLHRPRMLDPEPYVGEMSAVTLA 576 Query: 485 --RILDGNKRVQEAACSAF----ATLEEEACTELVPYLSYILDTL 523 R D ++ V+E A S L + +L P L +LD L Sbjct: 577 RLRATDLDQEVKERAISCMGHLVGHLGDRLGDDLEPTLLLLLDRL 621 >gi|112420977 TBP-interacting protein isoform 2 [Homo sapiens] Length = 1119 Score = 33.9 bits (76), Expect = 0.69 Identities = 40/165 (24%), Positives = 69/165 (41%), Gaps = 24/165 (14%) Query: 380 LDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMV--------- 430 L LA V L H+ L+ G++F + S + A +QG++ Sbjct: 367 LTELAGVLPGSLAEHMPVLVSGIIFS---LADRSSSSTIRMDALAFLQGLLGTEPAEAFH 423 Query: 431 PYLPELIPHLIQCLSDKKALVRSIACWTLSRY--AHWVVSQPPDMHLKPLMTELLK---- 484 P+LP L+P ++ C++D + + A L A W + +P + +P + E+ Sbjct: 424 PHLPILLPPVMACVADSFYKIAAEALVVLQELVRALWPLHRPRMLDPEPYVGEMSAVTLA 483 Query: 485 --RILDGNKRVQEAACSAF----ATLEEEACTELVPYLSYILDTL 523 R D ++ V+E A S L + +L P L +LD L Sbjct: 484 RLRATDLDQEVKERAISCMGHLVGHLGDRLGDDLEPTLLLLLDRL 528 >gi|89886480 zinedin isoform 2 [Homo sapiens] Length = 760 Score = 33.9 bits (76), Expect = 0.69 Identities = 16/50 (32%), Positives = 31/50 (62%), Gaps = 1/50 (2%) Query: 322 EDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAEDDDDDDALSDWN 371 EDE D + ++ HK + V LP +A P+ ++ E+DD +DA+++++ Sbjct: 272 EDED-SDEDDELDSVQHKKQRVKLPSKALVPEMEDEDEEDDSEDAINEFD 320 >gi|89886477 zinedin isoform 1 [Homo sapiens] Length = 753 Score = 33.9 bits (76), Expect = 0.69 Identities = 16/50 (32%), Positives = 31/50 (62%), Gaps = 1/50 (2%) Query: 322 EDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAEDDDDDDALSDWN 371 EDE D + ++ HK + V LP +A P+ ++ E+DD +DA+++++ Sbjct: 272 EDED-SDEDDELDSVQHKKQRVKLPSKALVPEMEDEDEEDDSEDAINEFD 320 >gi|54112117 splicing factor 3b, subunit 1 isoform 1 [Homo sapiens] Length = 1304 Score = 33.9 bits (76), Expect = 0.69 Identities = 33/116 (28%), Positives = 56/116 (48%), Gaps = 11/116 (9%) Query: 369 DWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPE-WVVKESGILVLG--AIAEGC 425 D +R +A A V+A+ +P LLP LK + + W + +GI ++ AI GC Sbjct: 621 DEYVRNTTARAFAVVASALG---IPSLLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGC 677 Query: 426 MQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVS---QPPDMHLKPL 478 ++P+L L+ + L D++ VR+I+ ++ A + D LKPL Sbjct: 678 --AILPHLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAATPYGIESFDSVLKPL 731 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.138 0.420 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 34,241,237 Number of Sequences: 37866 Number of extensions: 1512218 Number of successful extensions: 5048 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 17 Number of HSP's successfully gapped in prelim test: 44 Number of HSP's that attempted gapping in prelim test: 4833 Number of HSP's gapped (non-prelim): 203 length of query: 887 length of database: 18,247,518 effective HSP length: 111 effective length of query: 776 effective length of database: 14,044,392 effective search space: 10898448192 effective search space used: 10898448192 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.