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Search of human proteins with 209693444
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|209693444 myotilin isoform b [Homo sapiens]
(314 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209693444 myotilin isoform b [Homo sapiens] 630 0.0
gi|5803106 myotilin isoform a [Homo sapiens] 630 0.0
gi|153792294 myopalladin [Homo sapiens] 248 4e-66
gi|93102361 palladin [Homo sapiens] 243 2e-64
gi|110349721 titin isoform novex-3 [Homo sapiens] 127 1e-29
gi|110349719 titin isoform N2-A [Homo sapiens] 127 1e-29
gi|110349717 titin isoform novex-2 [Homo sapiens] 127 1e-29
gi|110349713 titin isoform novex-1 [Homo sapiens] 127 1e-29
gi|110349715 titin isoform N2-B [Homo sapiens] 127 1e-29
gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens] 95 7e-20
gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] 95 7e-20
gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens] 95 7e-20
gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens] 95 7e-20
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 91 1e-18
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 91 1e-18
gi|118572606 hemicentin 1 [Homo sapiens] 91 2e-18
gi|61888896 roundabout, axon guidance receptor, homolog 2 isofor... 86 3e-17
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 85 7e-17
gi|126517478 peroxidasin homolog-like [Homo sapiens] 85 1e-16
gi|109150416 peroxidasin [Homo sapiens] 84 2e-16
gi|222352127 sidekick 2 [Homo sapiens] 82 8e-16
gi|169217528 PREDICTED: similar to sidekick homolog 2 (chicken) ... 82 8e-16
gi|40255157 leucine-rich repeats and immunoglobulin-like domains... 82 8e-16
gi|209862903 leucine-rich repeats and immunoglobulin-like domain... 82 8e-16
gi|19743806 roundabout 1 isoform b [Homo sapiens] 81 1e-15
gi|4506569 roundabout 1 isoform a [Homo sapiens] 81 1e-15
gi|224994173 roundabout 1 isoform d [Homo sapiens] 81 1e-15
gi|224994171 roundabout 1 isoform c [Homo sapiens] 81 1e-15
gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo ... 81 1e-15
gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo ... 81 1e-15
>gi|209693444 myotilin isoform b [Homo sapiens]
Length = 314
Score = 630 bits (1625), Expect = 0.0
Identities = 314/314 (100%), Positives = 314/314 (100%)
Query: 1 MARRLLGPQNAAAVFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQ 60
MARRLLGPQNAAAVFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQ
Sbjct: 1 MARRLLGPQNAAAVFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQ 60
Query: 61 EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKG 120
EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKG
Sbjct: 61 EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKG 120
Query: 121 LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGD 180
LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGD
Sbjct: 121 LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGD 180
Query: 181 SVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVS 240
SVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVS
Sbjct: 181 SVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVS 240
Query: 241 AVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGLNVKQAFNPEGEFQ 300
AVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGLNVKQAFNPEGEFQ
Sbjct: 241 AVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGLNVKQAFNPEGEFQ 300
Query: 301 RLAAQSGLYESEEL 314
RLAAQSGLYESEEL
Sbjct: 301 RLAAQSGLYESEEL 314
>gi|5803106 myotilin isoform a [Homo sapiens]
Length = 498
Score = 630 bits (1625), Expect = 0.0
Identities = 314/314 (100%), Positives = 314/314 (100%)
Query: 1 MARRLLGPQNAAAVFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQ 60
MARRLLGPQNAAAVFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQ
Sbjct: 185 MARRLLGPQNAAAVFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQ 244
Query: 61 EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKG 120
EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKG
Sbjct: 245 EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKG 304
Query: 121 LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGD 180
LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGD
Sbjct: 305 LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGD 364
Query: 181 SVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVS 240
SVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVS
Sbjct: 365 SVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVS 424
Query: 241 AVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGLNVKQAFNPEGEFQ 300
AVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGLNVKQAFNPEGEFQ
Sbjct: 425 AVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGLNVKQAFNPEGEFQ 484
Query: 301 RLAAQSGLYESEEL 314
RLAAQSGLYESEEL
Sbjct: 485 RLAAQSGLYESEEL 498
>gi|153792294 myopalladin [Homo sapiens]
Length = 1320
Score = 248 bits (634), Expect = 4e-66
Identities = 130/311 (41%), Positives = 192/311 (61%), Gaps = 17/311 (5%)
Query: 19 DDSG-----AQDSQQHNSEHARLQVPTSQVRSRSTSRGDVN---------DQDAIQEKFY 64
DD G A + Q S L V + +RSR TS G + D++ +QE+F+
Sbjct: 1012 DDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFF 1071
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P F+Q P +M EGR CR+D KVSGLP P+++W LNG+ V D HKM+V E G+HSL
Sbjct: 1072 RPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSL 1131
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
+ + + DAG Y C+A N+ G+ +F+++L V+AKE K+AP+ + K Q+ V EG V+L
Sbjct: 1132 LIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRL 1191
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
EC++ +PPP +WK++NE + +RIS++QD TG LLI+ K DAGWYT+SA NE
Sbjct: 1192 ECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNE 1251
Query: 245 AGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGLNVKQAFNP-EGEFQRLA 303
AG+ +C RLD+ A+ + +P P + VRP+ S+Y +L KGL++ AF+ E
Sbjct: 1252 AGIVSCTARLDIYAQWHHQIPPP--MSVRPSGSRYGSLTSKGLDIFSAFSSMESTMVYSC 1309
Query: 304 AQSGLYESEEL 314
+ + ES+EL
Sbjct: 1310 SSRSVVESDEL 1320
Score = 75.9 bits (185), Expect = 4e-14
Identities = 60/233 (25%), Positives = 97/233 (41%), Gaps = 30/233 (12%)
Query: 62 KFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLH-KMIVSEKG 120
K P F + ++ + EG K+ G+P P V W+ +G+ + + H KM G
Sbjct: 941 KCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDG 1000
Query: 121 LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLA---------------------- 158
SL E + D G Y +A N G + + L V +
Sbjct: 1001 TCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQE 1060
Query: 159 ------KEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRI 212
+E P F+ P EG +L+C++S +PPP+L W N + V +
Sbjct: 1061 RDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHK 1120
Query: 213 SLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLP 265
L ++ TG +LLI + ++DAG Y A N+ G + + L V A+ + P
Sbjct: 1121 MLVRE-TGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAP 1172
Score = 61.2 bits (147), Expect = 1e-09
Identities = 43/170 (25%), Positives = 72/170 (42%), Gaps = 4/170 (2%)
Query: 27 QQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKF-YPPRFIQVPENMSIDEGRFCRM 85
+Q ++ + S+ T+ G +E PPRF Q + + EG ++
Sbjct: 229 EQQEAKRREAEQAASEAAGGDTTPGSSPSSLYYEEPLGQPPRFTQKLRSREVPEGTRVQL 288
Query: 86 DFKVSGLPAPDVSWYLNGRTVQ-SDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNR 144
D V G+P P V WY G+ ++ S D+H IV LHSL D G Y+C A N
Sbjct: 289 DCIVVGIPPPQVRWYCEGKELENSPDIH--IVQAGNLHSLTIAEAFEEDTGRYSCFASNI 346
Query: 145 AGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPP 194
G + + ++ + + K + ++ + + V SA+ PP
Sbjct: 347 YGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPP 396
Score = 57.8 bits (138), Expect = 1e-08
Identities = 31/114 (27%), Positives = 55/114 (48%)
Query: 147 EATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQ 206
E+ +Q D + AP+F + + +V EG V C+I IP PK++W ++ + +
Sbjct: 927 ESDDEIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQIS 986
Query: 207 FNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARP 260
+ + ++ G +L I+ D G YT+ A N G +C+ L V + P
Sbjct: 987 KRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLP 1040
Score = 52.8 bits (125), Expect = 4e-07
Identities = 29/102 (28%), Positives = 49/102 (48%), Gaps = 7/102 (6%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ-SDDLH------KMIVSE 118
P F ++ +N+S EG+ + +V G P+P V WY G ++ S D + +
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494
Query: 119 KGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE 160
+ + +L+ V A D+G + C A N+ G + QL V E
Sbjct: 495 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNE 536
Score = 46.2 bits (108), Expect = 4e-05
Identities = 31/107 (28%), Positives = 51/107 (47%), Gaps = 8/107 (7%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV- 222
AP+F Q+ EG V EC++ P PK+ W R +++ + D L +
Sbjct: 434 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 493
Query: 223 -----TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTL 264
TL+I +V +D+G +T +A N+ G + +L V R N+ L
Sbjct: 494 PEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHV--RGNEDL 538
Score = 42.0 bits (97), Expect = 7e-04
Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 2/90 (2%)
Query: 165 PMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTL 224
P F K +S++V EG V+L+C + IPPP++ W + ++ + D + N +T
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLT- 327
Query: 225 LIKDVNKKDAGWYTVSAVNEAGVTTCNTRL 254
I + ++D G Y+ A N G + + +
Sbjct: 328 -IAEAFEEDTGRYSCFASNIYGTDSTSAEI 356
>gi|93102361 palladin [Homo sapiens]
Length = 1106
Score = 243 bits (620), Expect = 2e-64
Identities = 110/213 (51%), Positives = 155/213 (72%)
Query: 44 RSRSTSRGDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNG 103
R RS SR ++ + IQE+F+ P F+Q P ++++ EG+ CRMD KVSGLP PD+SW L+G
Sbjct: 889 RPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDG 948
Query: 104 RTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKR 163
+ V+ D HKM+V E G+HSLI E V + DAG Y C+A NRAG+ +F+++L V AKE +
Sbjct: 949 KPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK 1008
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
P+FI K Q+ V +G V+LEC++ +PPP++FWK+ NE + +TDR+S++QDN G +
Sbjct: 1009 PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYIC 1068
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
LLI+ K+DAGWYTVSA NEAG+ +C RLDV
Sbjct: 1069 LLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
Score = 78.6 bits (192), Expect = 7e-15
Identities = 80/299 (26%), Positives = 125/299 (41%), Gaps = 42/299 (14%)
Query: 1 MARRLLGPQNAAAVFQAQDDSGAQDSQQH--NSEHARL--QVPTSQVRSRSTSRGD-VND 55
MARRLLG ++A VF Q+ +Q++ +S RL ++ RS GD V
Sbjct: 708 MARRLLGA-DSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQY 766
Query: 56 QDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMI 115
D E P F ++ I EG +V+G P P + W+ +G+ + H I
Sbjct: 767 GDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTI 826
Query: 116 VSE-KGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLA---------------- 158
+ G SL D G Y +A N G + T +L V A
Sbjct: 827 QRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPH 886
Query: 159 ------------------KEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKR 200
+E P F+ P V EG +++C++S +P P L W+
Sbjct: 887 VRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQL 946
Query: 201 NNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 259
+ + V+ ++ L ++N G +L+I+ V +DAG YT A N AG + + L V A+
Sbjct: 947 DGKPVRPDSAHKMLVREN-GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 1004
Score = 60.8 bits (146), Expect = 1e-09
Identities = 62/270 (22%), Positives = 105/270 (38%), Gaps = 77/270 (28%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTV----------QSDDLHKMI 115
PRFIQ + + EG ++ +V+G P P V W+ G+ + + DLH +I
Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
Query: 116 VSEK-----GLHSLI---------------FEVVRASDAGAYACVAKNRAG------EAT 149
++E G ++ + E ++D+ + + K+RAG + T
Sbjct: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKT 390
Query: 150 FTVQLDVLAKEHKRA-----------------------------------PMFIYKPQSK 174
+V L + + K P+F + Q+
Sbjct: 391 TSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNT 450
Query: 175 KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV------TLLIKD 228
V EG V LEC++ PP ++ W R +Q + D L + TL+I +
Sbjct: 451 AVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAE 510
Query: 229 VNKKDAGWYTVSAVNEAGVTTCNTRLDVTA 258
+DAG +T SA N+ G T +L VT+
Sbjct: 511 TFPEDAGIFTCSARNDYGSATSTAQLVVTS 540
Score = 57.0 bits (136), Expect = 2e-08
Identities = 47/194 (24%), Positives = 81/194 (41%), Gaps = 24/194 (12%)
Query: 36 LQVPTSQVRSRSTSRGDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAP 95
L VP QV S ++ + D ++PP F + +N ++ EG+ ++ +V G P
Sbjct: 414 LSVPVQQVHSPTSY---LCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPL 470
Query: 96 DVSWYLNGRTVQSDDLHKMI-------VSEKGLHSLIFEVVRASDAGAYACVAKNRAGEA 148
V W+ G +Q +++ + + +L+ DAG + C A+N G A
Sbjct: 471 QVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSA 530
Query: 149 TFTVQLDVLAKEHKRAPM----------FIYKPQSKKVLEGDSVKL----ECQISAIPPP 194
T T QL V + + F + P +LE S++L +I + P
Sbjct: 531 TSTAQLVVTSANTENCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNP 590
Query: 195 KLFWKRNNEMVQFN 208
+L R +QFN
Sbjct: 591 ELGLSRAALQMQFN 604
Score = 55.5 bits (132), Expect = 6e-08
Identities = 33/105 (31%), Positives = 49/105 (46%), Gaps = 1/105 (0%)
Query: 58 AIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTV-QSDDLHKMIV 116
A +E PP FI+ +N + +G R++ +V G+P P + W ++ S D M
Sbjct: 1002 AAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQ 1061
Query: 117 SEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEH 161
G L+ + DAG Y AKN AG + T +LDV H
Sbjct: 1062 DNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYISRH 1106
Score = 53.1 bits (126), Expect = 3e-07
Identities = 30/91 (32%), Positives = 49/91 (53%), Gaps = 1/91 (1%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP FI K +S++V EG V LEC+++ P P++ W + + NT I ++ + T
Sbjct: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELH-NTPDIQIHCEGGDLHT 328
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRL 254
L+I + + D G YT A N +G T + +
Sbjct: 329 LIIAEAFEDDTGRYTCLATNPSGSDTTSAEV 359
>gi|110349721 titin isoform novex-3 [Homo sapiens]
Length = 5604
Score = 127 bits (320), Expect = 1e-29
Identities = 66/216 (30%), Positives = 115/216 (53%)
Query: 61 EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKG 120
E+ Y P F+ P + EG+ R D KV G P P+ W+ +G+ + +D HK+++ E G
Sbjct: 1452 ERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDG 1511
Query: 121 LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGD 180
SLI SD+G + VA+NRAG ++ +V L V A EH+ PMF+ K ++ + EG
Sbjct: 1512 TQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGS 1571
Query: 181 SVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVS 240
++++ + + P P + W +N++++ + + G L I +D+ WYT +
Sbjct: 1572 RLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTAT 1631
Query: 241 AVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTF 276
A+N+AG T +++V + P K + R T+
Sbjct: 1632 AINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTY 1667
Score = 92.8 bits (229), Expect = 3e-19
Identities = 62/213 (29%), Positives = 109/213 (51%), Gaps = 13/213 (6%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVS-EKGLHSL 124
P F Q +++ + EG + +SG P P+VSW+ +G+ + + L + +S G L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
V +++G Y+ A N +G+AT T +L L K P F+ + QS V +G V+L
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAEL--LVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTD-RISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
+ +++ IP P + + R+ +Q + D +IS D +LLI + +D+G Y+V+A N
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGD---LYSLLIAEAYPEDSGTYSVNATN 180
Query: 244 EAGVTTCNTRL------DVTARPNQTLPAPKQL 270
G T L +V A+ +T+ + Q+
Sbjct: 181 SVGRATSTAELLVQGEEEVPAKKTKTIVSTAQI 213
Score = 84.7 bits (208), Expect = 1e-16
Identities = 60/231 (25%), Positives = 94/231 (40%), Gaps = 42/231 (18%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP + +N+++ EG ++ +SG P+P V+WY ++S + I + G+ L
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESS-IDFQITFQSGIARL 1000
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDV----------------LAKEHKR----- 163
+ A D+G + C A N AG + + L V E KR
Sbjct: 1001 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1060
Query: 164 --------------------APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNE 203
AP FI KP +K++EG SV CQ+ P P ++WK++
Sbjct: 1061 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1120
Query: 204 MVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRL 254
+ Y TG L+I DAG YT+ N+ G T+ + L
Sbjct: 1121 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 74.3 bits (181), Expect = 1e-13
Identities = 61/228 (26%), Positives = 90/228 (39%), Gaps = 37/228 (16%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PPRFI + I E V G+P P+V WY ++ D++ +I EKG H+L
Sbjct: 5379 PPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTL 5438
Query: 125 IFEVVRASDAGAYACVAKNRAGEAT---FTVQLD-----VLAKEHK-------------- 162
V SD+ Y C A N GEA F D V+AK+ K
Sbjct: 5439 KIRNVCLSDSATYRCRAVNCVGEAICRGFLTMGDSEIFAVIAKKSKVTLSSLMEELVLKS 5498
Query: 163 -------------RAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNT 209
P FI G + +C + P P ++W ++ ++VQ
Sbjct: 5499 NYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLVQGR- 5557
Query: 210 DRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVT 257
R ++ + TG L I + K D G Y A N++G+ L +T
Sbjct: 5558 -RFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMAESFAALTLT 5604
Score = 64.3 bits (155), Expect = 1e-10
Identities = 39/126 (30%), Positives = 64/126 (50%), Gaps = 1/126 (0%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP F+Q ++M++ +G R+ +V+G+P P V +Y +G +QS L I E L+SL
Sbjct: 103 PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQS-SLDFQISQEGDLYSL 161
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
+ D+G Y+ A N G AT T +L V +E A + ++ E ++
Sbjct: 162 LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRI 221
Query: 185 ECQISA 190
E +I A
Sbjct: 222 EKKIEA 227
Score = 62.8 bits (151), Expect = 4e-10
Identities = 52/214 (24%), Positives = 90/214 (42%), Gaps = 20/214 (9%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP+ +Q + +++ G+ R +SG P P +SWY + + + K + + L
Sbjct: 3238 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3297
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE--HKRAPMFIYKP------QSKKV 176
+ E DA Y C AKN G AT + L V E M +Y P Q
Sbjct: 3298 LIEAF-PEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVT 3356
Query: 177 LEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGW 236
EG + +C++S ++ ++ ++ R++ ++D L I + +D G
Sbjct: 3357 SEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDT---YQLEIAEAYPEDEGT 3413
Query: 237 YTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQL 270
YT A N G V++ N +L AP+ +
Sbjct: 3414 YTFVASNAVG--------QVSSTANLSLEAPESI 3439
Score = 62.0 bits (149), Expect = 7e-10
Identities = 52/176 (29%), Positives = 78/176 (44%), Gaps = 16/176 (9%)
Query: 96 DVSWYLNGRTV--QSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQ 153
D WY +G + Q + HK +V E+ +H + R SDAG Y V AG +V
Sbjct: 3176 DAHWYKDGIEINFQVQERHKYVV-ERRIHRMFISETRQSDAGEYTFV----AGRNRSSVT 3230
Query: 154 LDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRIS 213
L V A E P + + Q V G + IS P PK+ W + +++ +T
Sbjct: 3231 LYVNAPE---PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKC 3285
Query: 214 LYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV----TARPNQTLP 265
+ + TLL+ + +DA YT A N+ GV T + L V P+Q +P
Sbjct: 3286 KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP 3341
Score = 60.1 bits (144), Expect = 3e-09
Identities = 36/117 (30%), Positives = 59/117 (50%), Gaps = 2/117 (1%)
Query: 140 VAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWK 199
V R + T T ++ + P + ++ V+EG+SV LEC IS P P + W
Sbjct: 918 VLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWY 977
Query: 200 RNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
R + ++ + D +Q R L+I++ +D+G +T SAVNEAG + + L V
Sbjct: 978 REDYQIESSIDFQITFQSGIAR--LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 59.7 bits (143), Expect = 3e-09
Identities = 62/264 (23%), Positives = 108/264 (40%), Gaps = 44/264 (16%)
Query: 51 GDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD 110
GD+ D++ Q+ F+ + + CR+ G P V W +G+ +++ +
Sbjct: 1692 GDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLT--PIGDPTMVVEWLHDGKPLEAAN 1749
Query: 111 LHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAG----EATFTV-------------- 152
+MI +E G SL + V + D+G C A N+ G AT V
Sbjct: 1750 RLRMI-NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPE 1808
Query: 153 ---------QLDVLAKE-----------HKRAPMFIYKPQSKKVLEGDSVKLECQISAIP 192
+L+ +A E K+ P + P+ +VLEG++ + C+++ P
Sbjct: 1809 GRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYP 1868
Query: 193 PPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
PK+ W N ++++ + R + D G L I D D G V+A N GV
Sbjct: 1869 QPKVNWYLNGQLIR-KSKRFRVRYD--GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKV 1925
Query: 253 RLDVTARPNQTLPAPKQLRVRPTF 276
+L++ R + + RP F
Sbjct: 1926 KLEIQQREDFRSVLRRAPEPRPEF 1949
Score = 54.3 bits (129), Expect = 1e-07
Identities = 35/102 (34%), Positives = 50/102 (49%), Gaps = 3/102 (2%)
Query: 163 RAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV 222
+AP F QS VLEG + E IS P P++ W R+ +++ +T + GR
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 223 TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV---TARPN 261
L I V K ++G Y++ A N +G T L V TA PN
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPN 105
Score = 53.5 bits (127), Expect = 2e-07
Identities = 38/158 (24%), Positives = 66/158 (41%), Gaps = 4/158 (2%)
Query: 7 GPQNAAAVFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYPP 66
G + +A +D+ + Q LQ + R G + Q++ P
Sbjct: 1784 GTDHTSATLIVKDEKSLVEESQLPEGRKGLQ--RIEELERMAHEGALTGVTTDQKEKQKP 1841
Query: 67 RFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIF 126
+ PE + + EG R +V+G P P V+WYLNG+ ++ + V G+H L
Sbjct: 1842 DIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKS--KRFRVRYDGIHYLDI 1899
Query: 127 EVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRA 164
++ D G A+N G V+L++ +E R+
Sbjct: 1900 VDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRS 1937
Score = 52.8 bits (125), Expect = 4e-07
Identities = 48/162 (29%), Positives = 72/162 (44%), Gaps = 11/162 (6%)
Query: 93 PAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTV 152
P V WY +G V D ++M S++ +H L + SDA Y+CV T T
Sbjct: 2201 PFVKVKWYKDGMEVHEGDKYRMH-SDRKVHFLSILTIDTSDAEDYSCVLVEDENVKT-TA 2258
Query: 153 QLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRI 212
+L V F+ + Q +V E S +LEC +S P + K + V+ ++
Sbjct: 2259 KLIV----EGAVVEFVKELQDIEVPESYSGELECIVS---PENIEGKWYHNDVELKSNGK 2311
Query: 213 SLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRL 254
GR L +KDV K+D G Y S V + TTC ++
Sbjct: 2312 YTITSRRGRQNLTVKDVTKEDQGEY--SFVIDGKKTTCKLKM 2351
Score = 52.8 bits (125), Expect = 4e-07
Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 1/117 (0%)
Query: 46 RSTSRGDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRT 105
RS S G N+ ++ PP FI+ + E +V GLP P V WY N
Sbjct: 5163 RSDSFGTPNEAIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSL 5222
Query: 106 VQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHK 162
++ D+ KM + SL ++ + G Y C A N GEA +D++ +E +
Sbjct: 5223 LEPDERIKM-ERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEER 5278
Score = 50.4 bits (119), Expect = 2e-06
Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 5/117 (4%)
Query: 52 DVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDL 111
D+++ +A++ F R +N I EG K+SG P P ++WY +G+ ++ +
Sbjct: 1282 DISESEAVESGF-DSRI----KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGER 1336
Query: 112 HKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFI 168
++M + G SL VV D G Y A N G A + +L V AP +I
Sbjct: 1337 YQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYI 1393
Score = 48.9 bits (115), Expect = 6e-06
Identities = 31/90 (34%), Positives = 46/90 (51%), Gaps = 4/90 (4%)
Query: 171 PQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVN 230
P+ + EGDS+ LEC IS P P + W +N +++ N + + N L IKDVN
Sbjct: 4165 PKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQN-QKFQFEEVNCSH-QLYIKDVN 4222
Query: 231 KKDAGWYTVSAVNEAGVTTCNTRLDVTARP 260
+D+G Y A N +G + D+T P
Sbjct: 4223 SQDSGKYKCVAENNSGAV--ESVSDLTVEP 4250
Score = 47.4 bits (111), Expect = 2e-05
Identities = 32/114 (28%), Positives = 56/114 (49%), Gaps = 3/114 (2%)
Query: 175 KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDA 234
++LEG V C++S P PK+ W ++ + ++ + +R + GR +L I V +D
Sbjct: 1301 RILEGMGVTFHCKMSGYPLPKIAWYKDGKRIK-HGERYQMDFLQDGRASLRIPVVLPEDE 1359
Query: 235 GWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGLN 288
G YT A N G C+ +L V P L AP + S+ +L+ + ++
Sbjct: 1360 GIYTAFASNIKGNAICSGKLYV--EPAAPLGAPTYIPTLEPVSRIRSLSPRSVS 1411
Score = 47.4 bits (111), Expect = 2e-05
Identities = 47/196 (23%), Positives = 80/196 (40%), Gaps = 7/196 (3%)
Query: 55 DQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKM 114
D+ + P+ + ++ ++ +G +V G P P+ WY NG ++ D
Sbjct: 2067 DKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYW 2126
Query: 115 IVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK 174
E + L+ V A D+ + A N AGE + L V AK+ F + Q
Sbjct: 2127 YWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ---LITFTQELQDV 2183
Query: 175 KVLEGDSV-KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD 233
E D++ EC+ S P K+ W ++ M D+ ++ D L I ++ D
Sbjct: 2184 VAKEKDTMATFECETSE-PFVKVKWYKDG-MEVHEGDKYRMHSDRKVHF-LSILTIDTSD 2240
Query: 234 AGWYTVSAVNEAGVTT 249
A Y+ V + V T
Sbjct: 2241 AEDYSCVLVEDENVKT 2256
Score = 47.0 bits (110), Expect = 2e-05
Identities = 28/84 (33%), Positives = 41/84 (48%), Gaps = 2/84 (2%)
Query: 165 PMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGR--V 222
P F K K VLEG+ V C++ A P P++ W NN + RI + +
Sbjct: 3504 PSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSS 3563
Query: 223 TLLIKDVNKKDAGWYTVSAVNEAG 246
+L IK V +D+G Y + A+N G
Sbjct: 3564 SLEIKRVQDRDSGSYRLLAINSEG 3587
Score = 46.6 bits (109), Expect = 3e-05
Identities = 42/141 (29%), Positives = 74/141 (52%), Gaps = 14/141 (9%)
Query: 99 WYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLA 158
WY N ++S+ + I S +G +L + V D G Y+ V + + T +++
Sbjct: 2299 WYHNDVELKSNGKYT-ITSRRGRQNLTVKDVTKEDQGEYSFVIDGK--KTTCKLKM---- 2351
Query: 159 KEHKRAPMFIYKPQS-KKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQD 217
K P+ I + S +KV EGD V+LE ++S + + W ++ + VQ +DR+ + D
Sbjct: 2352 ---KPRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQ-PSDRVHIVID 2406
Query: 218 NTGRVTLLIKDVNKKDAGWYT 238
+ LLI+D+ K+DAG Y+
Sbjct: 2407 KQSHM-LLIEDMTKEDAGNYS 2426
Score = 46.6 bits (109), Expect = 3e-05
Identities = 41/178 (23%), Positives = 79/178 (44%), Gaps = 15/178 (8%)
Query: 67 RFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIF 126
+ I+ P++++ E + VS P V W+ ++ D H++ VSE+ +H L+
Sbjct: 2796 KIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRL-VSERKVHKLML 2853
Query: 127 EVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLEC 186
+ + SDAG Y V +A V+ + K K I P++K + EC
Sbjct: 2854 QNISPSDAGEYTAVVGQLECKAKLFVETLHITKTMKN----IEVPETK------TASFEC 2903
Query: 187 QISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
++S P + W +N ++ + + Q + L+I + + +D+ YT N+
Sbjct: 2904 EVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQ--LIIMNTSTEDSAEYTFVCGND 2958
Score = 46.6 bits (109), Expect = 3e-05
Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 65 PPRFIQ-VPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGL-H 122
PP+ +Q +P++ EG ++ +SG P P V+W+ NG ++ + K E H
Sbjct: 4157 PPKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQ--KFQFEEVNCSH 4214
Query: 123 SLIFEVVRASDAGAYACVAKNRAGEATFTVQLDV 156
L + V + D+G Y CVA+N +G L V
Sbjct: 4215 QLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTV 4248
Score = 45.4 bits (106), Expect = 6e-05
Identities = 49/180 (27%), Positives = 84/180 (46%), Gaps = 25/180 (13%)
Query: 66 PRFIQVPENMS---IDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ-SDDLHKMIVSEKGL 121
PR I + + +S + EG +++ KVS L + + W +G+ VQ SD +H IV +K
Sbjct: 2353 PRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVH--IVIDKQS 2409
Query: 122 HSLIFEVVRASDAGAYA----CVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL 177
H L+ E + DAG Y+ + + +G + +DV+ P+ + V+
Sbjct: 2410 HMLLIEDMTKEDAGNYSFTIPALGLSTSGRVS-VYSVDVIT------PL-----KDVNVI 2457
Query: 178 EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
EG LEC++S + W N+E ++ DR+ T + L+I + D G Y
Sbjct: 2458 EGTKAVLECKVSVPDVTSVKWYLNDEQIK-PDDRVQAIVKGT-KQRLVINRTHASDEGPY 2515
Score = 45.4 bits (106), Expect = 6e-05
Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 1/96 (1%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP F+Q E+ + EG C G P P V+WY N + + + +I S + L
Sbjct: 3943 PPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQ-NFIIHSLENYSIL 4001
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE 160
V + G+ CV N+ G T L V AK+
Sbjct: 4002 TLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQ 4037
Score = 45.1 bits (105), Expect = 8e-05
Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP + QS+ V +G ++ P P+ W +N ++ +DRI Y
Sbjct: 2077 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIE-RSDRIYWYWPEDNVCE 2135
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 259
L+I+DV +D+ V A+N AG T+ + L V A+
Sbjct: 2136 LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2171
Score = 45.1 bits (105), Expect = 8e-05
Identities = 32/116 (27%), Positives = 50/116 (43%), Gaps = 6/116 (5%)
Query: 165 PMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTL 224
P F+ + +S++V EGDS C P P + W N+ + N + I +N +TL
Sbjct: 3944 PSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILTL 4003
Query: 225 LIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYL 280
V+ ++ G T N+ G + L V A+ + A K P F YL
Sbjct: 4004 --SSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQKHDVKAHKV----PVFHDYL 4053
Score = 43.9 bits (102), Expect = 2e-04
Identities = 35/121 (28%), Positives = 49/121 (40%), Gaps = 5/121 (4%)
Query: 64 YPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS 123
YPP I ++ EG+ R +VSG VSWY + ++ +M E
Sbjct: 3343 YPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQL 3401
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE---HKRAPMFIYKPQSKKVLEGD 180
I E D G Y VA N G+ + T L + A E H+R I + EG+
Sbjct: 3402 EIAEAY-PEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKELFSEGE 3460
Query: 181 S 181
S
Sbjct: 3461 S 3461
Score = 43.5 bits (101), Expect = 2e-04
Identities = 29/102 (28%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 62 KFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGL 121
+++ P F Q + EG ++ P P+++W+ N R + + L ++I +E L
Sbjct: 3500 EYFKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPT-GLRRIIKAESDL 3558
Query: 122 H----SLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
H SL + V+ D+G+Y +A N G A T L V+ K
Sbjct: 3559 HHHSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQK 3600
Score = 42.0 bits (97), Expect = 7e-04
Identities = 27/110 (24%), Positives = 52/110 (47%), Gaps = 4/110 (3%)
Query: 159 KEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDN 218
K+++ P FI +KV E ++ ++ +P P + W RN +++ +RI + +
Sbjct: 5177 KDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLE-PDERIKM--ER 5233
Query: 219 TGRV-TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAP 267
G V +L I ++ K + G Y AVN G +D+ + + + P
Sbjct: 5234 VGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIMPQEERVVALP 5283
Score = 39.7 bits (91), Expect = 0.004
Identities = 40/158 (25%), Positives = 61/158 (38%), Gaps = 13/158 (8%)
Query: 93 PAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTV 152
P V W + + +Q D K I EK +H L+ R SDAG Y VA A V
Sbjct: 3084 PDITVQWMKDDQELQITDRIK-IQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFV 3142
Query: 153 Q-LDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDR 211
+ DV + K+ I K ++ E + ++ W ++ + F
Sbjct: 3143 EGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAH----------WYKDGIEINFQVQE 3192
Query: 212 ISLYQDNTGRVTLLIKDVNKKDAGWYT-VSAVNEAGVT 248
Y + I + + DAG YT V+ N + VT
Sbjct: 3193 RHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVT 3230
Score = 34.3 bits (77), Expect = 0.15
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 3/69 (4%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGL-HSLIFEVVRA 131
+++++ EG ++ KVS V WYLN ++ DD + IV KG L+ A
Sbjct: 2452 KDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIV--KGTKQRLVINRTHA 2509
Query: 132 SDAGAYACV 140
SD G Y +
Sbjct: 2510 SDEGPYKLI 2518
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 127 bits (320), Expect = 1e-29
Identities = 66/216 (30%), Positives = 115/216 (53%)
Query: 61 EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKG 120
E+ Y P F+ P + EG+ R D KV G P P+ W+ +G+ + +D HK+++ E G
Sbjct: 1452 ERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDG 1511
Query: 121 LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGD 180
SLI SD+G + VA+NRAG ++ +V L V A EH+ PMF+ K ++ + EG
Sbjct: 1512 TQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGS 1571
Query: 181 SVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVS 240
++++ + + P P + W +N++++ + + G L I +D+ WYT +
Sbjct: 1572 RLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTAT 1631
Query: 241 AVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTF 276
A+N+AG T +++V + P K + R T+
Sbjct: 1632 AINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTY 1667
Score = 95.9 bits (237), Expect = 4e-20
Identities = 62/198 (31%), Positives = 92/198 (46%), Gaps = 7/198 (3%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIV--SEKGLH 122
PP F N + G R ++ P P V+WY +G+ ++ D K S+KGL+
Sbjct: 31689 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY 31748
Query: 123 SLIFEVVRASDAGAYACVAKNRAGE----ATFTVQLDVLAKEHKRAPMFIYKPQSKKVLE 178
L V D Y VA+N+ GE A TV L + PMF + + E
Sbjct: 31749 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQE 31808
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G SV E ++S IPPP L W+++ + + + I + + L I+D +D G+Y
Sbjct: 31809 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPN-IEIIHEGLDYYALHIRDTLPEDTGYYR 31867
Query: 239 VSAVNEAGVTTCNTRLDV 256
V+A N AG T+C L V
Sbjct: 31868 VTATNTAGSTSCQAHLQV 31885
Score = 93.2 bits (230), Expect = 3e-19
Identities = 58/203 (28%), Positives = 104/203 (51%), Gaps = 19/203 (9%)
Query: 65 PPRFIQVPENMSI-DEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS 123
PP+FI+ P + + G+ + +++G P VSWYL+G + + H + + GL +
Sbjct: 4860 PPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFID-GLAT 4918
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
R ++G Y C A+N AG A+ +++L V K P FI + + +V++ V+
Sbjct: 4919 FQISGARVENSGTYVCEARNDAGTASCSIELKV-----KEPPTFIRELKPVEVVKYSDVE 4973
Query: 184 LECQISAIPPPKLFWKRNNEMVQFN-----TDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
LEC+++ PP ++ W +NN ++ + TDR+S++ L I + D G Y
Sbjct: 4974 LECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVF-------NLHITKCDPSDTGEYQ 5026
Query: 239 VSAVNEAGVTTCNTRLDVTARPN 261
NE G +C+TR+ + P+
Sbjct: 5027 CIVSNEGGSCSCSTRVALKEPPS 5049
Score = 92.8 bits (229), Expect = 3e-19
Identities = 62/213 (29%), Positives = 109/213 (51%), Gaps = 13/213 (6%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVS-EKGLHSL 124
P F Q +++ + EG + +SG P P+VSW+ +G+ + + L + +S G L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
V +++G Y+ A N +G+AT T +L L K P F+ + QS V +G V+L
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAEL--LVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTD-RISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
+ +++ IP P + + R+ +Q + D +IS D +LLI + +D+G Y+V+A N
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGD---LYSLLIAEAYPEDSGTYSVNATN 180
Query: 244 EAGVTTCNTRL------DVTARPNQTLPAPKQL 270
G T L +V A+ +T+ + Q+
Sbjct: 181 SVGRATSTAELLVQGEEEVPAKKTKTIVSTAQI 213
Score = 84.7 bits (208), Expect = 1e-16
Identities = 60/231 (25%), Positives = 94/231 (40%), Gaps = 42/231 (18%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP + +N+++ EG ++ +SG P+P V+WY ++S + I + G+ L
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESS-IDFQITFQSGIARL 1000
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDV----------------LAKEHKR----- 163
+ A D+G + C A N AG + + L V E KR
Sbjct: 1001 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1060
Query: 164 --------------------APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNE 203
AP FI KP +K++EG SV CQ+ P P ++WK++
Sbjct: 1061 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1120
Query: 204 MVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRL 254
+ Y TG L+I DAG YT+ N+ G T+ + L
Sbjct: 1121 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 84.7 bits (208), Expect = 1e-16
Identities = 56/203 (27%), Positives = 97/203 (47%), Gaps = 7/203 (3%)
Query: 59 IQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD-LHKMIVS 117
IQE+ PP F + +++ G + +++G V WY +G ++ D+ L V
Sbjct: 6168 IQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVD 6227
Query: 118 EKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL 177
++ S +G Y+C A N G A+ + +L A+E K++P F KP S V+
Sbjct: 6228 NVATLKIL--QTDLSHSGQYSCSASNPLGTASSSARLT--AREPKKSPFFDIKPVSIDVI 6283
Query: 178 EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
G+S EC ++ P ++ W ++N+ ++ + NT + +L V K D+G Y
Sbjct: 6284 AGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRIL--KVGKGDSGQY 6341
Query: 238 TVSAVNEAGVTTCNTRLDVTARP 260
T A N+ G C+ +L V P
Sbjct: 6342 TCQATNDVGKDMCSAQLSVKEPP 6364
Score = 84.3 bits (207), Expect = 1e-16
Identities = 62/217 (28%), Positives = 106/217 (48%), Gaps = 11/217 (5%)
Query: 59 IQEKFYPPRFIQ-VPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVS 117
I+E+ PP F + + E + EG +++ +V+G V+WY N +Q ++
Sbjct: 8242 IKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFK 8301
Query: 118 EKGLHSLIFEVVRA--SDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKK 175
++L+ +V +A +DAG Y C N AG A T ++ KE K+ P+F
Sbjct: 8302 N---NTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSS--IVIKEPKKPPVFDQHLTPVT 8356
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V EG+ V+L C + P ++ W + ++ +DR S + +G L ++DV K D+G
Sbjct: 8357 VSEGEYVQLSCHVQGSEPIRIQWLKAGREIK-PSDRCS-FSFASGTAVLELRDVAKADSG 8414
Query: 236 WYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRV 272
Y A N AG T +++ + +P PA K+ V
Sbjct: 8415 DYVCKASNVAGSDTTKSKVTIKDKP-AVAPATKKAAV 8450
Score = 83.2 bits (204), Expect = 3e-16
Identities = 60/223 (26%), Positives = 104/223 (46%), Gaps = 16/223 (7%)
Query: 59 IQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSE 118
+QE+ PP F + ++ G D +SG VSWY +G+ ++ + +
Sbjct: 8050 VQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLD 8109
Query: 119 KGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLE 178
IF+ R S AG Y+C A N G A+ + +L + E K P F + +
Sbjct: 8110 NTATLNIFKTDR-SLAGQYSCTATNPIGSASSSARL--ILTEGKNPPFFDIRLAPVDAVV 8166
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G+S EC ++ P K+ W +++ ++ Y +N+ +T+L V+K D+G YT
Sbjct: 8167 GESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVL--KVDKGDSGQYT 8224
Query: 239 VSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLA 281
AVNE G +C +L++ K+ + P+F+K L+
Sbjct: 8225 CYAVNEVGKDSCTAQLNI-----------KERLIPPSFTKRLS 8256
Score = 82.8 bits (203), Expect = 4e-16
Identities = 53/197 (26%), Positives = 88/197 (44%), Gaps = 5/197 (2%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P ++ PE++ + G C ++ V+G P W+ +G+ + SD+ +K+ K + L
Sbjct: 7585 PATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNK-VSGL 7643
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
V SD+G Y+ +N G+ + T L V + P F K + L G SV +
Sbjct: 7644 KIINVAPSDSGVYSFEVQNPVGKDSCTASLQV--SDRTVPPSFTRKLKETNGLSGSSVVM 7701
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
EC++ PP + W + + DNT L + + + D+G YT A N
Sbjct: 7702 ECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNT--CALTVNMLEESDSGDYTCIATNM 7759
Query: 245 AGVTTCNTRLDVTARPN 261
AG C+ L V P+
Sbjct: 7760 AGSDECSAPLTVREPPS 7776
Score = 82.4 bits (202), Expect = 5e-16
Identities = 61/213 (28%), Positives = 93/213 (43%), Gaps = 6/213 (2%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P R I+ PE M++ G ++ V+G P W+ +GR + +D H + K + SL
Sbjct: 6644 PARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINK-VASL 6702
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
SD G Y+ KN G++ TV + V + P FI K + + G SV L
Sbjct: 6703 KIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHV--SDRIVPPSFIRKLKDVNAILGASVVL 6760
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
EC++S P + W ++ + S + +N TL + + D G YT A N
Sbjct: 6761 ECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENV--CTLNLSLLEPSDTGIYTCVAANV 6818
Query: 245 AGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFS 277
AG C+ L V P+ P + V P S
Sbjct: 6819 AGSDECSAVLTVQEPPSFE-QTPDSVEVLPGMS 6850
Score = 82.4 bits (202), Expect = 5e-16
Identities = 57/201 (28%), Positives = 94/201 (46%), Gaps = 10/201 (4%)
Query: 59 IQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSE 118
+ ++ PP F + + + G M+ KV G P VSW+ G + S ++ +++
Sbjct: 7675 VSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTD 7734
Query: 119 KGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLE 178
+L ++ SD+G Y C+A N AG + L V + P F+ KP VL
Sbjct: 7735 NTC-ALTVNMLEESDSGDYTCIATNMAGSDECSAPLTV-----REPPSFVQKPDPMDVLT 7788
Query: 179 GDSVKLECQISAIPPPKLFW-KRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
G +V + PP + W K ++E+V + +SL +D+ + L DV+ +G Y
Sbjct: 7789 GTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSL-EDSVAELELF--DVDTSQSGEY 7845
Query: 238 TVSAVNEAGVTTCNTRLDVTA 258
T NEAG +C T L + A
Sbjct: 7846 TCIVSNEAGKASCTTHLYIKA 7866
Score = 82.0 bits (201), Expect = 6e-16
Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 11/189 (5%)
Query: 65 PPRFIQVPENMSI-DEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKM-IVSEKGLH 122
PP+F++ E + +G +++ K+SG P VSW+ N + + M ++ L
Sbjct: 6363 PPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVAL- 6421
Query: 123 SLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSV 182
L A D+G Y C A N G+A+ + L V K P+F KP L+G V
Sbjct: 6422 -LTINEASAEDSGDYICEAHNGVGDASCSTALTV-----KAPPVFTQKPSPVGALKGSDV 6475
Query: 183 KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAV 242
L+C+IS PP ++ W ++ + V+ N+ + + + +L I ++ D G Y A
Sbjct: 6476 ILQCEISGTPPFEVVWVKDRKQVR-NSKKFKITSKHFD-TSLHILNLEASDVGEYHCKAT 6533
Query: 243 NEAGVTTCN 251
NE G TC+
Sbjct: 6534 NEVGSDTCS 6542
Score = 80.5 bits (197), Expect = 2e-15
Identities = 57/210 (27%), Positives = 90/210 (42%), Gaps = 6/210 (2%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P ++ M++ G C ++ KV+G P V WY +G+ + S HK K + SL
Sbjct: 5703 PAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNK-ISSL 5761
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
V DAG Y +N G+++ T +DV + P F + ++ + G S L
Sbjct: 5762 RILSVERQDAGTYTFQVQNNVGKSSCTAVVDV--SDRAVPPSFTRRLKNTGGVLGASCIL 5819
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
EC+++ P + W + + + DN TL + ++ D G YT A N
Sbjct: 5820 ECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNV--CTLQLNSLDSSDMGNYTCVAANV 5877
Query: 245 AGVTTCNTRLDVTARPNQTLPAPKQLRVRP 274
AG C L V P + P+ L V P
Sbjct: 5878 AGSDECRAVLTV-QEPPSFVKEPEPLEVLP 5906
Score = 80.5 bits (197), Expect = 2e-15
Identities = 62/221 (28%), Positives = 101/221 (45%), Gaps = 20/221 (9%)
Query: 45 SRSTSRGDVNDQDAIQEKFYPPRFIQVPE-NMSIDEGRFCRMDFKVSGLPAPDVSWYLNG 103
S + + Q +QE PPRFI+ E + + + F R + K+ G P V WY +
Sbjct: 7287 SNIAGKDSCSAQLGVQE---PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDE 7343
Query: 104 RTVQSDDLHKMI----VSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
+Q +M V+ +H+L E D+G Y C A N AG A+ + L V
Sbjct: 7344 TEIQESSKFRMSFVDSVAVLEMHNLSVE-----DSGDYTCEAHNAAGSASSSTSLKV--- 7395
Query: 160 EHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNT 219
K P+F KP + L+G V LEC++ PP + W ++ ++ + + + +N
Sbjct: 7396 --KEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELR-SGKKYKIMSENF 7452
Query: 220 GRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARP 260
++ I +V+ D G Y A N+ G TC + + A P
Sbjct: 7453 -LTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPP 7492
Score = 78.6 bits (192), Expect = 7e-15
Identities = 55/182 (30%), Positives = 94/182 (51%), Gaps = 6/182 (3%)
Query: 75 MSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDA 134
MSI+EG+ R+ K + A DV W LNG + + + ++ VS +L + D
Sbjct: 33048 MSINEGQ--RLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSD-QTLTIKQASHRDE 33104
Query: 135 GAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPP 194
G C++K + G L L+KE AP FI +P+S+ + EG +V C+IS P P
Sbjct: 33105 GILTCISKTKEGIVKCQYDL-TLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSP 33163
Query: 195 KLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRL 254
++ W +NN + +++ +S+ + + +L I++ + D+G YT+ A N G + L
Sbjct: 33164 EIEWFKNNLPISISSN-VSISR-SRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASL 33221
Query: 255 DV 256
V
Sbjct: 33222 MV 33223
Score = 77.8 bits (190), Expect = 1e-14
Identities = 53/197 (26%), Positives = 83/197 (42%), Gaps = 2/197 (1%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKG-LHSL 124
P F + N+++ + KV+G P P V WY G+ + +D L I KG H L
Sbjct: 30928 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 30987
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
I V DA Y A N+ G + T L+V P + + L G+ V +
Sbjct: 30988 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSI 31047
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
+ S P P + W++ +++ N + + + V +KDAG+Y V A N
Sbjct: 31048 KIPFSGKPDPVITWQKGQDLID-NNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNR 31106
Query: 245 AGVTTCNTRLDVTARPN 261
G+ LDV P+
Sbjct: 31107 FGIDQKTVELDVADVPD 31123
Score = 77.0 bits (188), Expect = 2e-14
Identities = 61/233 (26%), Positives = 104/233 (44%), Gaps = 6/233 (2%)
Query: 59 IQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSE 118
I+ + PP F + +++ G + +++G VSWY +G + DD +
Sbjct: 7109 IKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDG-VLLKDDANLQTSFV 7167
Query: 119 KGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLE 178
+ +L S G Y C A N G A+ + +L + EH+ P F KP S +
Sbjct: 7168 HNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKL--ILSEHEVPPFFDLKPVSVDLAL 7225
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G+S +C ++ P K+ W ++N ++ + +NT +T+L V K DAG YT
Sbjct: 7226 GESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVL--KVGKGDAGQYT 7283
Query: 239 VSAVNEAGVTTCNTRLDVTARPNQTLP-APKQLRVRPTFSKYLALNGKGLNVK 290
A N AG +C+ +L V P P ++ + F++Y G +K
Sbjct: 7284 CYASNIAGKDSCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIK 7336
Score = 76.6 bits (187), Expect = 3e-14
Identities = 59/218 (27%), Positives = 103/218 (47%), Gaps = 23/218 (10%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P +F++ + SI++G+ ++ +G P V+W NG V + +EK S
Sbjct: 7867 PAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEK---SA 7923
Query: 125 IFEVVRAS--DAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSV 182
I E+ ++ DAG Y C +N +G+ + + Q+ +L P F+ + + KV GDS
Sbjct: 7924 ILEIPSSTVEDAGQYNCYIENASGKDSCSAQILIL-----EPPYFVKQLEPVKVSVGDSA 7978
Query: 183 KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAV 242
L+CQ++ P + W + + ++ T +++N TL+ V+ D+G Y A
Sbjct: 7979 SLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNV--ATLVFNQVDINDSGEYICKAE 8036
Query: 243 NEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYL 280
N G + +T L V Q LP P+FS+ L
Sbjct: 8037 NSVGEVSASTFLTV---QEQKLP--------PSFSRQL 8063
Score = 75.5 bits (184), Expect = 6e-14
Identities = 54/196 (27%), Positives = 86/196 (43%), Gaps = 9/196 (4%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PPRF++ ++S G+ ++ + G V W+ + + + + I + + +L
Sbjct: 7491 PPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATL 7550
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
F V ++AG Y C KN AG L VL + KP+S KV GD+ L
Sbjct: 7551 QFSRVEPANAGKYTCQIKNDAGMQECFATLSVL-----EPATIVEKPESIKVTTGDTCTL 7605
Query: 185 ECQISAIPPPKLFW-KRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
EC ++ P W K E+ N +IS + +G L I +V D+G Y+ N
Sbjct: 7606 ECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSG---LKIINVAPSDSGVYSFEVQN 7662
Query: 244 EAGVTTCNTRLDVTAR 259
G +C L V+ R
Sbjct: 7663 PVGKDSCTASLQVSDR 7678
Score = 74.7 bits (182), Expect = 1e-13
Identities = 59/209 (28%), Positives = 93/209 (44%), Gaps = 10/209 (4%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP F + P + +G ++ ++ G P VSWY + R ++S +K I+SE L S+
Sbjct: 7398 PPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYK-IMSENFLTSI 7456
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
V A+D G Y C A N G T + + K P F+ K + G V+L
Sbjct: 7457 HILNVDAADIGEYQCKATNDVGSDTCVGSIAL-----KAPPRFVKKLSDISTVVGKEVQL 7511
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISL-YQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
+ I P + W ++ + +D I + Y +N TL V +AG YT N
Sbjct: 7512 QTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENI--ATLQFSRVEPANAGKYTCQIKN 7569
Query: 244 EAGVTTCNTRLDVTARPNQTLPAPKQLRV 272
+AG+ C L V P + P+ ++V
Sbjct: 7570 DAGMQECFATLSV-LEPATIVEKPESIKV 7597
Score = 73.9 bits (180), Expect = 2e-13
Identities = 65/222 (29%), Positives = 103/222 (46%), Gaps = 18/222 (8%)
Query: 37 QVPTSQVRSRSTSRGDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPD 96
QV + +S T+ DV+D+ PP F + +N G C ++ KV+G
Sbjct: 5777 QVQNNVGKSSCTAVVDVSDRAV------PPSFTRRLKNTGGVLGASCILECKVAGSSPIS 5830
Query: 97 VSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDV 156
V+W+ + S ++ S+ + +L + +SD G Y CVA N AG L V
Sbjct: 5831 VAWFHEKTKIVSGAKYQTTFSD-NVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTV 5889
Query: 157 LAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRN-NEMVQFNTDRISLY 215
+ P F+ +P+ +VL G +V I PP K+ W R E+V+ DR ++Y
Sbjct: 5890 -----QEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVK--GDRCNIY 5942
Query: 216 -QDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
+D + L D+++ +G YT N AG +C TRL V
Sbjct: 5943 FEDTVAELELFNIDISQ--SGEYTCVVSNNAGQASCTTRLFV 5982
Score = 73.2 bits (178), Expect = 3e-13
Identities = 53/198 (26%), Positives = 99/198 (50%), Gaps = 11/198 (5%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P FI+ E + + ++ +V V+W +G+ + +K+ +K + +L
Sbjct: 3644 PHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDK-IATLE 3702
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQ-SKKVLEGDSVKL 184
+ + D+G Y C A N AG ++ + + V + P F+ K S +L G+S +L
Sbjct: 3703 IPLAKLKDSGTYVCTASNEAGSSSCSATVTV-----REPPSFVKKVDPSYLMLPGESARL 3757
Query: 185 ECQISAIPPPKLFWKRNN-EMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
C++ P ++ W +NN E+ + NT R +Y N+ + L I DV +D+G Y+ AVN
Sbjct: 3758 HCKLKGSPVIQVTWFKNNKELSESNTVR--MYFVNSEAI-LDITDVKVEDSGSYSCEAVN 3814
Query: 244 EAGVTTCNTRLDVTARPN 261
+ G +C+T + + P+
Sbjct: 3815 DVGSDSCSTEIVIKEPPS 3832
Score = 72.8 bits (177), Expect = 4e-13
Identities = 65/245 (26%), Positives = 110/245 (44%), Gaps = 22/245 (8%)
Query: 25 DSQQHNS---EHARLQVPTSQVRSR---------STSRGDVNDQDAIQEKFYPPRFIQVP 72
DS+ H + + A L++P +++ + S + + + ++ PP FI+
Sbjct: 6688 DSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKL 6747
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 132
++++ G ++ +VSG V W+ +G + S + SE + +L ++ S
Sbjct: 6748 KDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSE-NVCTLNLSLLEPS 6806
Query: 133 DAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIP 192
D G Y CVA N AG + L V + P F P S +VL G S+ I P
Sbjct: 6807 DTGIYTCVAANVAGSDECSAVLTV-----QEPPSFEQTPDSVEVLPGMSLTFTSVIRGTP 6861
Query: 193 PPKLFW-KRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCN 251
P K+ W K + E+V + ISL T L + +V ++G Y+ N+AG +C
Sbjct: 6862 PFKVKWFKGSRELVPGESCNISLEDFVT---ELELFEVQPLESGDYSCLVTNDAGSASCT 6918
Query: 252 TRLDV 256
T L V
Sbjct: 6919 THLFV 6923
Score = 72.4 bits (176), Expect = 5e-13
Identities = 57/228 (25%), Positives = 95/228 (41%), Gaps = 8/228 (3%)
Query: 64 YPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS 123
YPP F+ P++++ G+ + V+G P + W +G + S + I + H
Sbjct: 3549 YPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAAL-SPSPNWRISDAENKHI 3607
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
L + D G Y+C A N+ G +L ++ K H FI + + + V
Sbjct: 3608 LELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPH-----FIKELEPVQSAINKKVH 3662
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
LECQ+ + W ++ + + D ++D TL I KD+G Y +A N
Sbjct: 3663 LECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIA--TLEIPLAKLKDSGTYVCTASN 3720
Query: 244 EAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGLNVKQ 291
EAG ++C+ + V P+ + P S L KG V Q
Sbjct: 3721 EAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQ 3768
Score = 71.6 bits (174), Expect = 8e-13
Identities = 52/196 (26%), Positives = 92/196 (46%), Gaps = 9/196 (4%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F P ++ + G + V+G ++W + + ++ + + H I
Sbjct: 6271 PFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRI 6330
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL-EGDSVKL 184
+V + D+G Y C A N G+ + QL V K P F+ K ++ KV +G+S++L
Sbjct: 6331 LKVGKG-DSGQYTCQATNDVGKDMCSAQLSV-----KEPPKFVKKLEASKVAKQGESIQL 6384
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
EC+IS P K+ W RN+ + + + ++ +T I + + +D+G Y A N
Sbjct: 6385 ECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLT--INEASAEDSGDYICEAHNG 6442
Query: 245 AGVTTCNTRLDVTARP 260
G +C+T L V A P
Sbjct: 6443 VGDASCSTALTVKAPP 6458
Score = 70.9 bits (172), Expect = 1e-12
Identities = 48/187 (25%), Positives = 87/187 (46%), Gaps = 9/187 (4%)
Query: 65 PPRFIQVPENMSIDE-GRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS 123
PP+F++ E I + G R++ K++G P V W+ N + + D ++M + +
Sbjct: 5422 PPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDS-VAV 5480
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
+ + D+G + C A+N AG + + ++ V K P+F P + L+ V
Sbjct: 5481 IQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIV-----KEPPVFSSFPPIVETLKNAEVS 5535
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
LEC++S PP ++ W ++ Q + + ++ I +V+ D G Y A N
Sbjct: 5536 LECELSGTPPFEVVWYKDKR--QLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQN 5593
Query: 244 EAGVTTC 250
E G TC
Sbjct: 5594 EVGSDTC 5600
Score = 70.9 bits (172), Expect = 1e-12
Identities = 52/198 (26%), Positives = 87/198 (43%), Gaps = 5/198 (2%)
Query: 57 DAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIV 116
+A+ PP FI+ E++ G + KV G P +SWY ++S +KM
Sbjct: 7011 EALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKM-Q 7069
Query: 117 SEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKV 176
+ + SL+ V SD G Y+C A N G + L + K K P F K +
Sbjct: 7070 FKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVL--VIKARKLPPFFARKLKDVHE 7127
Query: 177 LEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGW 236
G V EC+I+ P ++ W ++ +++ + + + + N TL I ++ G
Sbjct: 7128 TLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNV--ATLQILQTDQSHIGQ 7185
Query: 237 YTVSAVNEAGVTTCNTRL 254
Y SA N G + + +L
Sbjct: 7186 YNCSASNPLGTASSSAKL 7203
Score = 70.5 bits (171), Expect = 2e-12
Identities = 57/192 (29%), Positives = 85/192 (44%), Gaps = 10/192 (5%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F + N+ CR+D K++G VSW+ +G+ + + D +++ E G SL
Sbjct: 4113 PFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVE-GTASLE 4171
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLE 185
V +DAG + C A N G + L V + P F+ KP SK VL G +V L+
Sbjct: 4172 IIRVDMNDAGNFTCRATNSVGSKDSSGALIV-----QEPPSFVTKPGSKDVLPGSAVCLK 4226
Query: 186 CQISAIPPPKLFW-KRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
P + W K N E+V + I+ + L+K D+G YT N
Sbjct: 4227 STFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVK---TSDSGTYTCKVSNV 4283
Query: 245 AGVTTCNTRLDV 256
AG C+ L V
Sbjct: 4284 AGGVECSANLFV 4295
Score = 70.5 bits (171), Expect = 2e-12
Identities = 56/227 (24%), Positives = 100/227 (44%), Gaps = 13/227 (5%)
Query: 46 RSTSRGDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRT 105
RS+ + +N D I PP F + + M +G F ++ V+G + W+ + +
Sbjct: 4659 RSSCKARINVLDLI----IPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQE 4714
Query: 106 VQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAP 165
+ + + +K + I ++ +D+G Y C A N+AG + L V K P
Sbjct: 4715 ISASEKYKFSFHDNTAFLEISQL-EGTDSGTYTCSATNKAGHNQCSGHLTV-----KEPP 4768
Query: 166 MFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLL 225
F+ KPQS+ V V+L+ + P + W ++N+ + R S+++D+T +L
Sbjct: 4769 YFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAAR-SVWKDDTS-TSLE 4826
Query: 226 IKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRV 272
+ D+G Y N+ G T L V P Q + P + V
Sbjct: 4827 LFAAKATDSGTYICQLSNDVGTATSKATLFV-KEPPQFIKKPSPVLV 4872
Score = 69.7 bits (169), Expect = 3e-12
Identities = 50/198 (25%), Positives = 91/198 (45%), Gaps = 11/198 (5%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS- 123
PP F+ P + + G + G + W+ + + S ++++ L S
Sbjct: 4205 PPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGG--SCYITKEALESS 4262
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLE-GDSV 182
L +V+ SD+G Y C N AG + L V K F+ K + ++L+ GD+
Sbjct: 4263 LELYLVKTSDSGTYTCKVSNVAGGVECSANLFV-----KEPATFVEKLEPSQLLKKGDAT 4317
Query: 183 KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAV 242
+L C+++ PP K+ W N+ ++ ++ + ++T L + DV +D+G Y A
Sbjct: 4318 QLACKVTGTPPIKITWFANDREIKESSKHRMSFVEST--AVLRLTDVGIEDSGEYMCEAQ 4375
Query: 243 NEAGVTTCNTRLDVTARP 260
NEAG C++ + V P
Sbjct: 4376 NEAGSDHCSSIVIVKESP 4393
Score = 69.7 bits (169), Expect = 3e-12
Identities = 48/208 (23%), Positives = 95/208 (45%), Gaps = 9/208 (4%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP FI+ + + + + ++ +V+G P +V+W N R ++S + + + +L
Sbjct: 4954 PPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTL-TDRVSVFNL 5012
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
SD G Y C+ N G + + ++ + K P FI K ++ + S
Sbjct: 5013 HITKCDPSDTGEYQCIVSNEGGSCSCSTRVAL-----KEPPSFIKKIENTTTVLKSSATF 5067
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
+ ++ PP + W ++++++ + + + D+ TL I+ V+ +G YT A NE
Sbjct: 5068 QSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVA--TLQIRSVDNGHSGRYTCQAKNE 5125
Query: 245 AGVTTCNTRLDVTARPNQTLPAPKQLRV 272
+GV C L + P Q + K + V
Sbjct: 5126 SGVERCYAFL-LVQEPAQIVEKAKSVDV 5152
Score = 69.7 bits (169), Expect = 3e-12
Identities = 46/197 (23%), Positives = 91/197 (46%), Gaps = 12/197 (6%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P F++ + S++ G+ ++ +G V+W +G + + + ++ +EK +
Sbjct: 5985 PAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEK---TC 6041
Query: 125 IFEVVRAS--DAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSV 182
I E++ ++ DAG Y+C +N AG + L P F+ + + + GDSV
Sbjct: 6042 ILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTL-----EPPYFVTELEPLEAAVGDSV 6096
Query: 183 KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAV 242
L+CQ++ P + W + + ++ + + + +N TL+ VN D+G YT A
Sbjct: 6097 SLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNV--ATLVFNKVNINDSGEYTCKAE 6154
Query: 243 NEAGVTTCNTRLDVTAR 259
N G + T + R
Sbjct: 6155 NSIGTASSKTVFRIQER 6171
Score = 69.3 bits (168), Expect = 4e-12
Identities = 56/214 (26%), Positives = 89/214 (41%), Gaps = 12/214 (5%)
Query: 59 IQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSE 118
I+E PP F Q +++ EG + ++ V G + W GR ++ D +
Sbjct: 8339 IKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFAS 8398
Query: 119 KGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDV-----LAKEHKRAPM-----FI 168
G L V +D+G Y C A N AG T ++ + +A K+A + F+
Sbjct: 8399 -GTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFV 8457
Query: 169 YKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKD 228
+PQS +V+E + ++ P P + W + R+ ++Q L I+D
Sbjct: 8458 SEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGD-EAKLEIRD 8516
Query: 229 VNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQ 262
K D+G Y A NE G N L V R Q
Sbjct: 8517 TTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQ 8550
Score = 68.6 bits (166), Expect = 7e-12
Identities = 51/185 (27%), Positives = 81/185 (43%), Gaps = 8/185 (4%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP FI+ E I G + +VSG ++SW+ + + ++S +++ S+K L L
Sbjct: 3830 PPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLF-SQKSLVCL 3888
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
++D G Y CV N G+ + K P F+ K L G +V L
Sbjct: 3889 EIFSFNSADVGEYECVVANEVGKCGC-----MATHLLKEPPTFVKKVDDLIALGGQTVTL 3943
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
+ + P + W + E+++ +I + N G L+I DV G YT A NE
Sbjct: 3944 QAAVRGSEPISVTWMKGQEVIR-EDGKIKMSFSN-GVAVLIIPDVQISFGGKYTCLAENE 4001
Query: 245 AGVTT 249
AG T
Sbjct: 4002 AGSQT 4006
Score = 68.6 bits (166), Expect = 7e-12
Identities = 51/198 (25%), Positives = 82/198 (41%), Gaps = 12/198 (6%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP F++ PE + + G+ + G P V+W+ R + D + +
Sbjct: 5892 PPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELE 5951
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
+F + S +G Y CV N AG+A+ T +L V K F+ + V G S+ L
Sbjct: 5952 LFN-IDISQSGEYTCVVSNNAGQASCTTRLFV-----KEPAAFLKRLSDHSVEPGKSIIL 6005
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVN--KKDAGWYTVSAV 242
E + P + WK++ FN T T +++ +N K+DAG Y+
Sbjct: 6006 ESTYTGTLPISVTWKKDG----FNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIE 6061
Query: 243 NEAGVTTCNTRLDVTARP 260
NEAG C + P
Sbjct: 6062 NEAGRDVCGALVSTLEPP 6079
Score = 68.6 bits (166), Expect = 7e-12
Identities = 59/225 (26%), Positives = 97/225 (43%), Gaps = 15/225 (6%)
Query: 51 GDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD 110
GD + A+ K PP F Q P + +G + ++SG P +V W + + V++
Sbjct: 6444 GDASCSTALTVKA-PPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSK 6502
Query: 111 LHKMIVS--EKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFI 168
K+ + LH L E ASD G Y C A N G T + + + K P F+
Sbjct: 6503 KFKITSKHFDTSLHILNLE---ASDVGEYHCKATNEVGSDTCSCSV-----KFKEPPRFV 6554
Query: 169 YKPQSKKVLEGDSVKLECQISAIPPPKLFW-KRNNEMVQFNTDRISLYQDNTGRVTLLIK 227
K L GD+V+L + P + W K E+++ + + + DN TL +
Sbjct: 6555 KKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNI--ATLQLG 6612
Query: 228 DVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRV 272
++G Y N+AG+ C+ L V P + + P+ + V
Sbjct: 6613 SPEASNSGKYICQIKNDAGMRECSAVLTV-LEPARIIEKPEPMTV 6656
Score = 67.8 bits (164), Expect = 1e-11
Identities = 62/222 (27%), Positives = 89/222 (40%), Gaps = 19/222 (8%)
Query: 64 YPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS 123
YPP I ++ EG+ R +VSG VSWY + ++ +M E
Sbjct: 3343 YPPAIITPLQDTVTSEGQPARFQCRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFEDTYQL 3401
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEH--------------KRAPMFIY 169
I E D G Y VA N G+ + T L + A E K AP+
Sbjct: 3402 EIAEAY-PEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKR 3460
Query: 170 KPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDV 229
K + +V G K C+I + P + W + + + +D+ S+ + + +L I
Sbjct: 3461 KIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI-YESDKCSI-RSSKYISSLEILRT 3518
Query: 230 NKKDAGWYTVSAVNEAGVTTCNTRLDVT-ARPNQTLPAPKQL 270
D G YT A NE G +C L VT A P L PK L
Sbjct: 3519 QVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSL 3560
Score = 67.8 bits (164), Expect = 1e-11
Identities = 50/198 (25%), Positives = 93/198 (46%), Gaps = 9/198 (4%)
Query: 65 PPRFIQVPE-NMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS 123
P F++ E + + +G ++ KV+G P ++W+ N R ++ H+M E
Sbjct: 4298 PATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVL 4357
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
+ +V D+G Y C A+N AG + + V K +P F + + +VL+ V
Sbjct: 4358 RLTDV-GIEDSGEYMCEAQNEAGSDHCSSIVIV-----KESPYFTKEFKPIEVLKEYDVM 4411
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
L +++ PP ++ W ++N +++ + QD+ V+L I DAG Y N
Sbjct: 4412 LLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHL--VSLQILKFVAADAGEYQCRVTN 4469
Query: 244 EAGVTTCNTRLDVTARPN 261
E G + C+ R+ + P+
Sbjct: 4470 EVGSSICSARVTLREPPS 4487
Score = 67.4 bits (163), Expect = 2e-11
Identities = 50/208 (24%), Positives = 96/208 (46%), Gaps = 7/208 (3%)
Query: 58 AIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVS 117
A+ PP F+ E + G + +V+G P VSWY ++ ++ +
Sbjct: 6071 ALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFT 6130
Query: 118 EKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL 177
+ +L+F V +D+G Y C A+N G A+ + +E + P F + + +
Sbjct: 6131 -NNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRI--QERQLPPSFARQLKDIEQT 6187
Query: 178 EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
G V L C+++ P ++ W R+ +++ + + + + DN + +L D++ +G Y
Sbjct: 6188 VGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLS--HSGQY 6245
Query: 238 TVSAVNEAGVTTCNTRLDVTARPNQTLP 265
+ SA N G + + RL TAR + P
Sbjct: 6246 SCSASNPLGTASSSARL--TAREPKKSP 6271
Score = 67.0 bits (162), Expect = 2e-11
Identities = 53/197 (26%), Positives = 86/197 (43%), Gaps = 10/197 (5%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP F + M G M+ KVSG W+ +G+ + + ++++ E+ + SL
Sbjct: 5236 PPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSV-SL 5294
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
+ D Y C N AG+ + L V K P F+ KP ++ + +V+
Sbjct: 5295 EVNNLELEDTANYTCKVSNVAGDDACSGILTV-----KEPPSFLVKPGRQQAIPDSTVEF 5349
Query: 185 ECQISAIPPPKLFW-KRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
+ + PP K+ W K + E+V I L + +T + L D +K G YT N
Sbjct: 5350 KAILKGTPPFKIKWFKDDVELVSGPKCFIGL-EGSTSFLNLYSVDASK--TGQYTCHVTN 5406
Query: 244 EAGVTTCNTRLDVTARP 260
+ G +C T L VT P
Sbjct: 5407 DVGSDSCTTMLLVTEPP 5423
Score = 66.2 bits (160), Expect = 3e-11
Identities = 55/234 (23%), Positives = 105/234 (44%), Gaps = 29/234 (12%)
Query: 65 PPRFIQ-VPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTV-QSDDLHKMIVSEKGLH 122
PP F++ V + + G R+ K+ G P V+W+ N + + +S+ + V+ + +
Sbjct: 3736 PPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAI- 3794
Query: 123 SLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSV 182
L V+ D+G+Y+C A N G + + ++ + K P FI + ++ G +
Sbjct: 3795 -LDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVI-----KEPPSFIKTLEPADIVRGTNA 3848
Query: 183 KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAV 242
L+C++S P ++ W ++ + ++ ++ + L+ + V L I N D G Y
Sbjct: 3849 LLQCEVSGTGPFEISWFKDKKQIR-SSKKYRLFSQKS-LVCLEIFSFNSADVGEYECVVA 3906
Query: 243 NEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSK----YLALNGKGLNVKQA 292
NE G C A L+ PTF K +AL G+ + ++ A
Sbjct: 3907 NEVGKCGC--------------MATHLLKEPPTFVKKVDDLIALGGQTVTLQAA 3946
Score = 65.5 bits (158), Expect = 6e-11
Identities = 54/196 (27%), Positives = 86/196 (43%), Gaps = 10/196 (5%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP F++ +++ G+ + V G V+W ++ D KM S G+ L
Sbjct: 3923 PPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSN-GVAVL 3981
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
I V+ S G Y C+A+N AG T +L V K I + + +V GD L
Sbjct: 3982 IIPDVQISFGGKYTCLAENEAGSQTSVGELIV-----KEPAKIIERAELIQVTAGDPATL 4036
Query: 185 ECQISAIPPPKLFW-KRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
E ++ P K W K +V RIS +++N ++ +++ D+G YT N
Sbjct: 4037 EYTVAGTPELKPKWYKDGRPLVASKKYRIS-FKNNVAQLKFYSAELH--DSGQYTFEISN 4093
Query: 244 EAGVTTCNTRLDVTAR 259
E G ++C T V R
Sbjct: 4094 EVGSSSCETTFTVLDR 4109
Score = 64.7 bits (156), Expect = 1e-10
Identities = 48/196 (24%), Positives = 82/196 (41%), Gaps = 8/196 (4%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP F+Q P+ M + G V G P VSW+ + D + + +
Sbjct: 7774 PPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELE 7833
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
+F+ V S +G Y C+ N AG+A+ T L + K F+ + + +G + L
Sbjct: 7834 LFD-VDTSQSGEYTCIVSNEAGKASCTTHLYI-----KAPAKFVKRLNDYSIEKGKPLIL 7887
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
E + PP + WK+N V + R ++ + L I +DAG Y N
Sbjct: 7888 EGTFTGTPPISVTWKKNGINVT-PSQRCNITTTEKSAI-LEIPSSTVEDAGQYNCYIENA 7945
Query: 245 AGVTTCNTRLDVTARP 260
+G +C+ ++ + P
Sbjct: 7946 SGKDSCSAQILILEPP 7961
Score = 64.3 bits (155), Expect = 1e-10
Identities = 39/126 (30%), Positives = 64/126 (50%), Gaps = 1/126 (0%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP F+Q ++M++ +G R+ +V+G+P P V +Y +G +QS L I E L+SL
Sbjct: 103 PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQS-SLDFQISQEGDLYSL 161
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
+ D+G Y+ A N G AT T +L V +E A + ++ E ++
Sbjct: 162 LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRI 221
Query: 185 ECQISA 190
E +I A
Sbjct: 222 EKKIEA 227
Score = 63.5 bits (153), Expect = 2e-10
Identities = 56/223 (25%), Positives = 96/223 (43%), Gaps = 19/223 (8%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP FI+ EN + V+G P ++W + + + DD + I + +L
Sbjct: 5047 PPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDD-NVYISFVDSVATL 5105
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
V +G Y C AKN +G L V + + K +S V E D + L
Sbjct: 5106 QIRSVDNGHSGRYTCQAKNESGVERCYAFLLV-----QEPAQIVEKAKSVDVTEKDPMTL 5160
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
EC ++ P K+ W ++ + + + +++N + I+ V K+D+G YT N+
Sbjct: 5161 ECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNV--ASFRIQSVMKQDSGQYTFKVEND 5218
Query: 245 AGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGL 287
G ++C+ L V +Q +P P+F+K L K L
Sbjct: 5219 FGSSSCDAYLRVL---DQNIP--------PSFTKKLTKMDKVL 5250
Score = 63.5 bits (153), Expect = 2e-10
Identities = 46/196 (23%), Positives = 82/196 (41%), Gaps = 9/196 (4%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PPRF+ ++++ G + + G V W V + + I + + +L
Sbjct: 5609 PPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATL 5668
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
F ++AG Y C KN G L VL + + K V G++ L
Sbjct: 5669 QFAKAEPANAGKYICQIKNDGGMRENMATLMVL-----EPAVIVEKAGPMTVTVGETCTL 5723
Query: 185 ECQISAIPPPKLFWKRNNEMV-QFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
EC+++ P + W ++ +++ + S Y + +L I V ++DAG YT N
Sbjct: 5724 ECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKIS---SLRILSVERQDAGTYTFQVQN 5780
Query: 244 EAGVTTCNTRLDVTAR 259
G ++C +DV+ R
Sbjct: 5781 NVGKSSCTAVVDVSDR 5796
Score = 62.8 bits (151), Expect = 4e-10
Identities = 52/214 (24%), Positives = 90/214 (42%), Gaps = 20/214 (9%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP+ +Q + +++ G+ R +SG P P +SWY + + + K + + L
Sbjct: 3238 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3297
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE--HKRAPMFIYKP------QSKKV 176
+ E DA Y C AKN G AT + L V E M +Y P Q
Sbjct: 3298 LIEAF-PEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVT 3356
Query: 177 LEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGW 236
EG + +C++S ++ ++ ++ R++ ++D L I + +D G
Sbjct: 3357 SEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDT---YQLEIAEAYPEDEGT 3413
Query: 237 YTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQL 270
YT A N G V++ N +L AP+ +
Sbjct: 3414 YTFVASNAVG--------QVSSTANLSLEAPESI 3439
Score = 62.4 bits (150), Expect = 5e-10
Identities = 49/198 (24%), Positives = 86/198 (43%), Gaps = 11/198 (5%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP F+ P + G P + W+ + + S K + +G S
Sbjct: 5329 PPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGP--KCFIGLEGSTSF 5386
Query: 125 I-FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLE-GDSV 182
+ V AS G Y C N G + T L V P F+ K ++ K+++ GDS
Sbjct: 5387 LNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVT-----EPPKFVKKLEASKIVKAGDSS 5441
Query: 183 KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAV 242
+LEC+I+ P ++ W RN + + + D+ + + +++ +D+G + A
Sbjct: 5442 RLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQM--NNLSTEDSGDFICEAQ 5499
Query: 243 NEAGVTTCNTRLDVTARP 260
N AG T+C+T++ V P
Sbjct: 5500 NPAGSTSCSTKVIVKEPP 5517
Score = 62.0 bits (149), Expect = 7e-10
Identities = 52/176 (29%), Positives = 78/176 (44%), Gaps = 16/176 (9%)
Query: 96 DVSWYLNGRTV--QSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQ 153
D WY +G + Q + HK +V E+ +H + R SDAG Y V AG +V
Sbjct: 3176 DAHWYKDGIEINFQVQERHKYVV-ERRIHRMFISETRQSDAGEYTFV----AGRNRSSVT 3230
Query: 154 LDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRIS 213
L V A E P + + Q V G + IS P PK+ W + +++ +T
Sbjct: 3231 LYVNAPE---PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKC 3285
Query: 214 LYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV----TARPNQTLP 265
+ + TLL+ + +DA YT A N+ GV T + L V P+Q +P
Sbjct: 3286 KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP 3341
Score = 61.6 bits (148), Expect = 9e-10
Identities = 48/185 (25%), Positives = 81/185 (43%), Gaps = 11/185 (5%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP F P + + ++ ++SG P +V WY + R ++S +K ++ K H+
Sbjct: 5516 PPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYK--IASKNFHTS 5573
Query: 125 IFEV-VRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
I + V SD G Y C A+N G T + + K P F+ K S V+ G+ +
Sbjct: 5574 IHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKL-----KEPPRFVSKLNSLTVVAGEPAE 5628
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISL-YQDNTGRVTLLIKDVNKKDAGWYTVSAV 242
L+ I P + W + E V ++ I + + +N TL +AG Y
Sbjct: 5629 LQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENV--ATLQFAKAEPANAGKYICQIK 5686
Query: 243 NEAGV 247
N+ G+
Sbjct: 5687 NDGGM 5691
Score = 61.6 bits (148), Expect = 9e-10
Identities = 50/209 (23%), Positives = 84/209 (40%), Gaps = 30/209 (14%)
Query: 97 VSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDV 156
V+WY R +++ + ++ I E G+ L + + D G Y C N GE + +L V
Sbjct: 31600 VTWYFGVRQLENSEKYE-ITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 31658
Query: 157 LAKEH-----------------------KRAPMFIYKPQSKKVLEGDSVKLECQISAIPP 193
+R P F +K G++V+ I+ P
Sbjct: 31659 KGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPE 31718
Query: 194 PKLFWKRNNEMVQ-FNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
P + W ++ + ++ + D+ ++ + G L I V D YTV A N+ G +C
Sbjct: 31719 PHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKA 31778
Query: 253 RLDVTARPNQTLPAPKQLRVRPTFSKYLA 281
+L VT P P +RP F + LA
Sbjct: 31779 KLTVTLH-----PPPTDSTLRPMFKRLLA 31802
Score = 60.8 bits (146), Expect = 1e-09
Identities = 47/185 (25%), Positives = 87/185 (47%), Gaps = 8/185 (4%)
Query: 80 GRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYAC 139
G ++ ++ G P PD+ WY G+ + +KM S+ H+L D G Y C
Sbjct: 30547 GEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKM-SSDGRTHTLTVMTEEQEDEGVYTC 30605
Query: 140 VAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWK 199
+A N GE + +L +L + P + K + + G +++L P P + W
Sbjct: 30606 IATNEVGEVETSSKL-LLQATPQFHPGYPLKEKYYGAV-GSTLRLHVMYIGRPVPAMTWF 30663
Query: 200 RNNEMVQFNTDRISLYQDNTGRVT-LLIKDVNKK-DAGWYTVSAVNEAGVTTCNTRLDVT 257
+++Q N++ I++ +NT T L++K+V +K AG Y V N G +++
Sbjct: 30664 HGQKLLQ-NSENITI--ENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQ 30720
Query: 258 ARPNQ 262
+P++
Sbjct: 30721 DKPDK 30725
Score = 60.1 bits (144), Expect = 3e-09
Identities = 36/117 (30%), Positives = 59/117 (50%), Gaps = 2/117 (1%)
Query: 140 VAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWK 199
V R + T T ++ + P + ++ V+EG+SV LEC IS P P + W
Sbjct: 918 VLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWY 977
Query: 200 RNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
R + ++ + D +Q R L+I++ +D+G +T SAVNEAG + + L V
Sbjct: 978 REDYQIESSIDFQITFQSGIAR--LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 60.1 bits (144), Expect = 3e-09
Identities = 37/169 (21%), Positives = 79/169 (46%), Gaps = 8/169 (4%)
Query: 88 KVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGE 147
+V+G P +++W+ + ++S +K + + + I + V A+DAG Y C N G
Sbjct: 4415 EVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFV-AADAGEYQCRVTNEVGS 4473
Query: 148 ATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQF 207
+ + ++ + + P FI K +S L G + + + P + W ++++ +
Sbjct: 4474 SICSARVTL-----REPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITE 4528
Query: 208 NTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
+ + +++N +L + + K G Y A N+AG+ C+ L V
Sbjct: 4529 DDNIRMTFENNV--ASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSV 4575
Score = 60.1 bits (144), Expect = 3e-09
Identities = 43/197 (21%), Positives = 88/197 (44%), Gaps = 12/197 (6%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P F++ + S++ G ++ +G P VSW + + + + ++EK S
Sbjct: 6926 PATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEK---ST 6982
Query: 125 IFEVVRAS--DAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSV 182
I E++ ++ D Y+C+ +N AG+ + VL P FI + + + G+
Sbjct: 6983 ILEILESTIEDYAQYSCLIENEAGQDICEALVSVL-----EPPYFIEPLEHVEAVIGEPA 7037
Query: 183 KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAV 242
L+C++ P ++ W + + ++ +++N +L+I V+ D G Y+ A
Sbjct: 7038 TLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNV--ASLVINKVDHSDVGEYSCKAD 7095
Query: 243 NEAGVTTCNTRLDVTAR 259
N G + L + AR
Sbjct: 7096 NSVGAVASSAVLVIKAR 7112
Score = 59.7 bits (143), Expect = 3e-09
Identities = 62/264 (23%), Positives = 108/264 (40%), Gaps = 44/264 (16%)
Query: 51 GDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD 110
GD+ D++ Q+ F+ + + CR+ G P V W +G+ +++ +
Sbjct: 1692 GDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLT--PIGDPTMVVEWLHDGKPLEAAN 1749
Query: 111 LHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAG----EATFTV-------------- 152
+MI +E G SL + V + D+G C A N+ G AT V
Sbjct: 1750 RLRMI-NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPE 1808
Query: 153 ---------QLDVLAKE-----------HKRAPMFIYKPQSKKVLEGDSVKLECQISAIP 192
+L+ +A E K+ P + P+ +VLEG++ + C+++ P
Sbjct: 1809 GRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYP 1868
Query: 193 PPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
PK+ W N ++++ + R + D G L I D D G V+A N GV
Sbjct: 1869 QPKVNWYLNGQLIR-KSKRFRVRYD--GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKV 1925
Query: 253 RLDVTARPNQTLPAPKQLRVRPTF 276
+L++ R + + RP F
Sbjct: 1926 KLEIQQREDFRSVLRRAPEPRPEF 1949
Score = 58.2 bits (139), Expect = 1e-08
Identities = 46/166 (27%), Positives = 79/166 (47%), Gaps = 13/166 (7%)
Query: 74 NMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASD 133
N+ + E ++ +VS P +V WY + ++ I++E L+ + D
Sbjct: 12471 NIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYE-ILTEGRKRILVIQNAHLED 12528
Query: 134 AGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPP 193
AG Y C + + D K H+ A FI KPQ+ ++LEG+ + C IS
Sbjct: 12529 AGNYNCRLPSS--------RTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSISKESF 12580
Query: 194 PKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTV 239
P + WKR+++ ++ + D+ + D RV L++KD +D G Y V
Sbjct: 12581 P-VQWKRDDKTLE-SGDKYDVIADGKKRV-LVVKDATLQDMGTYVV 12623
Score = 57.8 bits (138), Expect = 1e-08
Identities = 50/208 (24%), Positives = 90/208 (43%), Gaps = 8/208 (3%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P + I+ E + + G +++ V+G P WY +GR + + ++ I + + L
Sbjct: 4016 PAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYR-ISFKNNVAQL 4074
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
F D+G Y N G ++ VL ++ AP F ++ + + +L
Sbjct: 4075 KFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDI--APFFTKPLRNVDSVVNGTCRL 4132
Query: 185 ECQISAIPPPKLFW-KRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
+C+I+ P ++ W K E+ + RI+ + G +L I V+ DAG +T A N
Sbjct: 4133 DCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVE---GTASLEIIRVDMNDAGNFTCRATN 4189
Query: 244 EAGVTTCNTRLDVTARPN-QTLPAPKQL 270
G + L V P+ T P K +
Sbjct: 4190 SVGSKDSSGALIVQEPPSFVTKPGSKDV 4217
Score = 57.8 bits (138), Expect = 1e-08
Identities = 58/217 (26%), Positives = 87/217 (40%), Gaps = 15/217 (6%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP FI+ E+ S G + G V+W + + DD +M E + SL
Sbjct: 4485 PPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTF-ENNVASL 4543
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
+ G Y C AKN AG + L V K + S V +GD L
Sbjct: 4544 YLSGIEVKHDGKYVCQAKNDAGIQRCSALLSV-----KEPATITEEAVSIDVTQGDPATL 4598
Query: 185 ECQISAIPPPKLFW-KRNNEMVQFNTDRISLYQDNTGRVTLL-IKDVNKKDAGWYTVSAV 242
+ + S W K E+ + +IS+ T V++L I KKD+G YT
Sbjct: 4599 QVKFSGTKEITAKWFKDGQELTLGSKYKISV----TDTVSILKIISTEKKDSGEYTFEVQ 4654
Query: 243 NEAGVTTCNTR---LDVTARPNQTLPAPKQLRVRPTF 276
N+ G ++C R LD+ P+ T K ++ +F
Sbjct: 4655 NDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSF 4691
Score = 55.5 bits (132), Expect = 6e-08
Identities = 34/125 (27%), Positives = 58/125 (46%), Gaps = 1/125 (0%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P FI P + +I+EG+ ++SG P+P++ W+ N + S + I + ++SL
Sbjct: 33134 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPI-SISSNVSISRSRNVYSLE 33192
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLE 185
SD+G Y AKN G+ + T L VL + + + + L+G
Sbjct: 33193 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQS 33252
Query: 186 CQISA 190
Q+SA
Sbjct: 33253 VQMSA 33257
Score = 54.3 bits (129), Expect = 1e-07
Identities = 35/102 (34%), Positives = 50/102 (49%), Gaps = 3/102 (2%)
Query: 163 RAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV 222
+AP F QS VLEG + E IS P P++ W R+ +++ +T + GR
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 223 TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV---TARPN 261
L I V K ++G Y++ A N +G T L V TA PN
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPN 105
Score = 54.3 bits (129), Expect = 1e-07
Identities = 33/129 (25%), Positives = 63/129 (48%), Gaps = 8/129 (6%)
Query: 141 AKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK----KVLEGDSVKLECQISAIPPPKL 196
A N GE+ ++ L+V+ ++ + P + + KV G+ V + ++ +P PK+
Sbjct: 15371 AVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKI 15430
Query: 197 FWKRNNEMVQFNTDRISLYQDNTGR----VTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
W +N +++ TD + + ++ R L I ++D G YTV+A N G N
Sbjct: 15431 EWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNV 15490
Query: 253 RLDVTARPN 261
++V RP+
Sbjct: 15491 HVEVYDRPS 15499
Score = 53.5 bits (127), Expect = 2e-07
Identities = 38/158 (24%), Positives = 66/158 (41%), Gaps = 4/158 (2%)
Query: 7 GPQNAAAVFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYPP 66
G + +A +D+ + Q LQ + R G + Q++ P
Sbjct: 1784 GTDHTSATLIVKDEKSLVEESQLPEGRKGLQ--RIEELERMAHEGALTGVTTDQKEKQKP 1841
Query: 67 RFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIF 126
+ PE + + EG R +V+G P P V+WYLNG+ ++ + V G+H L
Sbjct: 1842 DIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKS--KRFRVRYDGIHYLDI 1899
Query: 127 EVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRA 164
++ D G A+N G V+L++ +E R+
Sbjct: 1900 VDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRS 1937
Score = 53.1 bits (126), Expect = 3e-07
Identities = 43/153 (28%), Positives = 68/153 (44%), Gaps = 11/153 (7%)
Query: 117 SEKGLHSLIFEVVRASDAGAYACVAK--NRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK 174
+++ + L F V + G Y K N AG + + + + P I +
Sbjct: 16067 NKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFM 16126
Query: 175 KVLEGDSVKLECQISAIPPPKLFWKR-------NNEMVQFNTDRISLYQDNTGRVTLLIK 227
+V EG +V + +I +P P L W + N E V ++T L D+T TL+I
Sbjct: 16127 EVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDT--CTLVIP 16184
Query: 228 DVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARP 260
+ D G YT++AVN G + RL+V RP
Sbjct: 16185 QSRRSDTGLYTITAVNNLGTASKEMRLNVLGRP 16217
Score = 52.8 bits (125), Expect = 4e-07
Identities = 48/162 (29%), Positives = 72/162 (44%), Gaps = 11/162 (6%)
Query: 93 PAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTV 152
P V WY +G V D ++M S++ +H L + SDA Y+CV T T
Sbjct: 2201 PFVKVKWYKDGMEVHEGDKYRMH-SDRKVHFLSILTIDTSDAEDYSCVLVEDENVKT-TA 2258
Query: 153 QLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRI 212
+L V F+ + Q +V E S +LEC +S P + K + V+ ++
Sbjct: 2259 KLIV----EGAVVEFVKELQDIEVPESYSGELECIVS---PENIEGKWYHNDVELKSNGK 2311
Query: 213 SLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRL 254
GR L +KDV K+D G Y S V + TTC ++
Sbjct: 2312 YTITSRRGRQNLTVKDVTKEDQGEY--SFVIDGKKTTCKLKM 2351
Score = 52.8 bits (125), Expect = 4e-07
Identities = 40/147 (27%), Positives = 71/147 (48%), Gaps = 3/147 (2%)
Query: 115 IVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQ-LDVLAKEHKRAPMFIYKPQS 173
IV+E + + + + + + A N G++ V + V+AK+ P +
Sbjct: 24261 IVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNT 24320
Query: 174 KKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD 233
+ G+ +K+E + P P + W ++ E ++ T R+++ + T V L IK+ NK D
Sbjct: 24321 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLK-QTTRVNVEETATSTV-LHIKEGNKDD 24378
Query: 234 AGWYTVSAVNEAGVTTCNTRLDVTARP 260
G YTV+A N AG T N + V +P
Sbjct: 24379 FGKYTVTATNSAGTATENLSVIVLEKP 24405
Score = 52.4 bits (124), Expect = 5e-07
Identities = 32/143 (22%), Positives = 67/143 (46%), Gaps = 2/143 (1%)
Query: 123 SLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSV 182
SL+ ++ + A+N G + V + + P I P+ + G +
Sbjct: 18857 SLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKL 18916
Query: 183 KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAV 242
++E + P P WK+ + V + +++++ ++ + L+IKDV +KD+G+Y+++A
Sbjct: 18917 RIEAHVYGKPHPTCKWKKGEDEV-VTSSHLAVHKADSSSI-LIIKDVTRKDSGYYSLTAE 18974
Query: 243 NEAGVTTCNTRLDVTARPNQTLP 265
N +G T ++ V P P
Sbjct: 18975 NSSGTDTQKIKVVVMDAPGPPQP 18997
Score = 51.6 bits (122), Expect = 9e-07
Identities = 45/170 (26%), Positives = 74/170 (43%), Gaps = 15/170 (8%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 132
+++++ EG+ C M + S +P W+ NGR ++ HK V K +H L VRA
Sbjct: 8752 QDVTLKEGQTCTMTCQFS-VPNVKSEWFRNGRILKPQGRHKTEVEHK-VHKLTIADVRAE 8809
Query: 133 DAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIP 192
D G Y C ++ A ++ + + F + Q+ V E S EC++S
Sbjct: 8810 DQGQYTCKYEDLETSAELRIEAEPI--------QFTKRIQNIVVSEHQSATFECEVSFDD 8861
Query: 193 PPKLFWKRNNEMVQFNTDRISLYQDNTGRV-TLLIKDVNKKDAGWYTVSA 241
++K E+ T+ N GR + I +V D G Y+V A
Sbjct: 8862 AIVTWYKGPTEL----TESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIA 8907
Score = 51.2 bits (121), Expect = 1e-06
Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKM-IVSEKGLHS 123
PP+ +P ++SIDEG+ + +G P P+V+W GR + S + + I + L +
Sbjct: 33328 PPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTT 33387
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDV 156
LI V+ D G Y N G + TV + +
Sbjct: 33388 LIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 33420
Score = 50.4 bits (119), Expect = 2e-06
Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 5/117 (4%)
Query: 52 DVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDL 111
D+++ +A++ F R +N I EG K+SG P P ++WY +G+ ++ +
Sbjct: 1282 DISESEAVESGF-DSRI----KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGER 1336
Query: 112 HKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFI 168
++M + G SL VV D G Y A N G A + +L V AP +I
Sbjct: 1337 YQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYI 1393
Score = 50.1 bits (118), Expect = 3e-06
Identities = 48/189 (25%), Positives = 83/189 (43%), Gaps = 14/189 (7%)
Query: 60 QEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVS---WYLNGRTVQSDDLHKMIV 116
Q K P +F++ +++ + E F L +P + W +G ++ H+ I
Sbjct: 11109 QLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIA 11168
Query: 117 SEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKK- 175
K I +V + SDAG Y CV + E T T +L V + P+ K ++
Sbjct: 11169 DGKDRKLHIIDV-QLSDAGEYTCVLRLGNKEKTSTAKLVV-----EELPVRFVKTLEEEV 11222
Query: 176 -VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDA 234
V++G + L C+++ + W+++ ++V RI R L I D + DA
Sbjct: 11223 TVVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMR-ALTINDADDTDA 11279
Query: 235 GWYTVSAVN 243
G YTV+ N
Sbjct: 11280 GTYTVTVEN 11288
Score = 49.7 bits (117), Expect = 3e-06
Identities = 48/179 (26%), Positives = 73/179 (40%), Gaps = 14/179 (7%)
Query: 68 FIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFE 127
FI P+N+ I EG +S P V W + +T++S D + +I K L+ +
Sbjct: 12554 FISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIADGKK-RVLVVK 12611
Query: 128 VVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQ 187
D G Y + G A L V+ K P+ + +V E V C+
Sbjct: 12612 DATLQDMGTYVVMV----GAARAAAHLTVIEKLRIVVPL-----KDTRVKEQQEVVFNCE 12662
Query: 188 ISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
++ K W RN E + ++ I L +D TL I+D + D Y VS N G
Sbjct: 12663 VNT-EGAKAKWFRNEEAIFDSSKYIILQKDLV--YTLRIRDAHLDDQANYNVSLTNHRG 12718
Score = 49.7 bits (117), Expect = 3e-06
Identities = 34/133 (25%), Positives = 64/133 (48%), Gaps = 10/133 (7%)
Query: 67 RFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIF 126
R + P +M++ EG R G P P V+W G+ + + H++ ++ + F
Sbjct: 32562 RILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK---YKSTF 32618
Query: 127 EV--VRASDAGAYACVAKNRAG----EATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGD 180
E+ V+ASD G Y+ V +N G E T T+Q + ++ +P + P+ +V +
Sbjct: 32619 EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPE-PRVKSPE 32677
Query: 181 SVKLECQISAIPP 193
+VK ++ + P
Sbjct: 32678 AVKSPKRVKSPEP 32690
Score = 49.3 bits (116), Expect = 4e-06
Identities = 45/200 (22%), Positives = 85/200 (42%), Gaps = 17/200 (8%)
Query: 72 PENMSI-DEGR------FCRMDFKVSGLPAPDVSWYLNGRTVQSDD---LHKMIVSEKGL 121
PEN+ I D+G+ + R D+ +P++S+++ R SDD +HK + E
Sbjct: 18104 PENLHIADKGKTFVYLKWRRPDYDGG---SPNLSYHVERRLKGSDDWERVHKGSIKET-- 18158
Query: 122 HSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLE-GD 180
H ++ V + + KN GE+ + +V+ KE + P+ K ++ GD
Sbjct: 18159 HYMVDRCVE-NQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGD 18217
Query: 181 SVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVS 240
+++LE + P P++ W ++ + + + D G Y V+
Sbjct: 18218 TIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVT 18277
Query: 241 AVNEAGVTTCNTRLDVTARP 260
A N AG ++V +P
Sbjct: 18278 ATNTAGSFVAYATVNVLDKP 18297
Score = 48.5 bits (114), Expect = 8e-06
Identities = 50/182 (27%), Positives = 83/182 (45%), Gaps = 21/182 (11%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKG-LHSLIFEVVRA 131
+++++ G D ++S P V WYL G+ ++ D K++ +G +H+L V+
Sbjct: 12203 KDVTVTAGETATFDCELSYEDIP-VEWYLKGKKLEPSD--KVVPRSEGKVHTLTLRDVKL 12259
Query: 132 SDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKP-QSKKVLEGDSVKLECQISA 190
DAG AK+ A V K P+ KP + + V EG + LEC++S
Sbjct: 12260 EDAGEVQLTAKDFKTHANLFV---------KEPPVEFTKPLEDQTVEEGATAVLECEVSR 12310
Query: 191 IPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV-TLLIKDVNKKDAGWYTVSAVNEAGVTT 249
K+ W +N + + + + D GRV L+I D +D YT A + T+
Sbjct: 12311 -ENAKVKWFKNGTEI-LKSKKYEIVAD--GRVRKLVIHDCTPEDIKTYTCDAKDFK--TS 12364
Query: 250 CN 251
CN
Sbjct: 12365 CN 12366
Score = 48.5 bits (114), Expect = 8e-06
Identities = 33/111 (29%), Positives = 55/111 (49%), Gaps = 8/111 (7%)
Query: 51 GDVNDQDAIQEKFYPPRF---IQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTV- 106
G+V D ++++ P V + + + G R+ VSG P P V+W +N RT+
Sbjct: 16507 GEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLP 16566
Query: 107 QSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
Q + +S S++ + + S G Y+ +AKN AGE T+ +DVL
Sbjct: 16567 QEATIETTAISS----SMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVL 16613
Score = 47.4 bits (111), Expect = 2e-05
Identities = 32/114 (28%), Positives = 56/114 (49%), Gaps = 3/114 (2%)
Query: 175 KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDA 234
++LEG V C++S P PK+ W ++ + ++ + +R + GR +L I V +D
Sbjct: 1301 RILEGMGVTFHCKMSGYPLPKIAWYKDGKRIK-HGERYQMDFLQDGRASLRIPVVLPEDE 1359
Query: 235 GWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGLN 288
G YT A N G C+ +L V P L AP + S+ +L+ + ++
Sbjct: 1360 GIYTAFASNIKGNAICSGKLYV--EPAAPLGAPTYIPTLEPVSRIRSLSPRSVS 1411
Score = 47.4 bits (111), Expect = 2e-05
Identities = 47/196 (23%), Positives = 80/196 (40%), Gaps = 7/196 (3%)
Query: 55 DQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKM 114
D+ + P+ + ++ ++ +G +V G P P+ WY NG ++ D
Sbjct: 2067 DKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYW 2126
Query: 115 IVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK 174
E + L+ V A D+ + A N AGE + L V AK+ F + Q
Sbjct: 2127 YWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ---LITFTQELQDV 2183
Query: 175 KVLEGDSV-KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD 233
E D++ EC+ S P K+ W ++ M D+ ++ D L I ++ D
Sbjct: 2184 VAKEKDTMATFECETSE-PFVKVKWYKDG-MEVHEGDKYRMHSDRKVHF-LSILTIDTSD 2240
Query: 234 AGWYTVSAVNEAGVTT 249
A Y+ V + V T
Sbjct: 2241 AEDYSCVLVEDENVKT 2256
Score = 47.4 bits (111), Expect = 2e-05
Identities = 30/82 (36%), Positives = 42/82 (51%), Gaps = 2/82 (2%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G ++ IS P PK+ WK EM TDR+S+ R TL +KD + D+G Y
Sbjct: 28662 GSPFTIDVPISGRPAPKVTWKLE-EMRLKETDRVSI-TTTKDRTTLTVKDSMRGDSGRYF 28719
Query: 239 VSAVNEAGVTTCNTRLDVTARP 260
++ N AGV T + + V RP
Sbjct: 28720 LTLENTAGVKTFSVTVVVIGRP 28741
Score = 46.6 bits (109), Expect = 3e-05
Identities = 42/141 (29%), Positives = 74/141 (52%), Gaps = 14/141 (9%)
Query: 99 WYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLA 158
WY N ++S+ + I S +G +L + V D G Y+ V + + T +++
Sbjct: 2299 WYHNDVELKSNGKYT-ITSRRGRQNLTVKDVTKEDQGEYSFVIDGK--KTTCKLKM---- 2351
Query: 159 KEHKRAPMFIYKPQS-KKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQD 217
K P+ I + S +KV EGD V+LE ++S + + W ++ + VQ +DR+ + D
Sbjct: 2352 ---KPRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQ-PSDRVHIVID 2406
Query: 218 NTGRVTLLIKDVNKKDAGWYT 238
+ LLI+D+ K+DAG Y+
Sbjct: 2407 KQSHM-LLIEDMTKEDAGNYS 2426
Score = 46.6 bits (109), Expect = 3e-05
Identities = 41/178 (23%), Positives = 79/178 (44%), Gaps = 15/178 (8%)
Query: 67 RFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIF 126
+ I+ P++++ E + VS P V W+ ++ D H++ VSE+ +H L+
Sbjct: 2796 KIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRL-VSERKVHKLML 2853
Query: 127 EVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLEC 186
+ + SDAG Y V +A V+ + K K I P++K + EC
Sbjct: 2854 QNISPSDAGEYTAVVGQLECKAKLFVETLHITKTMKN----IEVPETK------TASFEC 2903
Query: 187 QISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
++S P + W +N ++ + + Q + L+I + + +D+ YT N+
Sbjct: 2904 EVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQ--LIIMNTSTEDSAEYTFVCGND 2958
Score = 46.6 bits (109), Expect = 3e-05
Identities = 40/148 (27%), Positives = 68/148 (45%), Gaps = 12/148 (8%)
Query: 41 SQVRSRSTSRGDVN--------DQDAIQEKFYPPRF---IQVPENMSIDEGRFCRMDFKV 89
+Q + R+ +R VN D I + PPR + + +++ G +D V
Sbjct: 19260 AQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATV 19319
Query: 90 SGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEAT 149
G P P VSW +G ++ + KM + ++ L +L V D+G Y A+N +G +
Sbjct: 19320 FGKPMPTVSWKKDGTLLKPAEGIKMAM-QRNLCTLELFSVNRKDSGDYTITAENSSGSKS 19378
Query: 150 FTVQLDVLAKEHKRAPMFIYKPQSKKVL 177
T++L VL K A + I K S + +
Sbjct: 19379 ATIKLKVLDKPGPPASVKINKMYSDRAM 19406
Score = 46.2 bits (108), Expect = 4e-05
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 6/123 (4%)
Query: 141 AKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQISAIPPPKLF 197
A+N GE T + ++ V+A++ AP K E + +L+ I P P +
Sbjct: 19957 AENENGEGTPS-EITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVS 20015
Query: 198 WKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVT 257
WK+ + + +T R+S+ + + TL++ D K DAG YT++ N AG + V
Sbjct: 20016 WKKGEDPLATDT-RVSV-ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVV 20073
Query: 258 ARP 260
+P
Sbjct: 20074 GKP 20076
Score = 45.4 bits (106), Expect = 6e-05
Identities = 49/180 (27%), Positives = 84/180 (46%), Gaps = 25/180 (13%)
Query: 66 PRFIQVPENMS---IDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ-SDDLHKMIVSEKGL 121
PR I + + +S + EG +++ KVS L + + W +G+ VQ SD +H IV +K
Sbjct: 2353 PRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVH--IVIDKQS 2409
Query: 122 HSLIFEVVRASDAGAYA----CVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL 177
H L+ E + DAG Y+ + + +G + +DV+ P+ + V+
Sbjct: 2410 HMLLIEDMTKEDAGNYSFTIPALGLSTSGRVS-VYSVDVIT------PL-----KDVNVI 2457
Query: 178 EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
EG LEC++S + W N+E ++ DR+ T + L+I + D G Y
Sbjct: 2458 EGTKAVLECKVSVPDVTSVKWYLNDEQIK-PDDRVQAIVKGT-KQRLVINRTHASDEGPY 2515
Score = 45.1 bits (105), Expect = 8e-05
Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP + QS+ V +G ++ P P+ W +N ++ +DRI Y
Sbjct: 2077 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIE-RSDRIYWYWPEDNVCE 2135
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 259
L+I+DV +D+ V A+N AG T+ + L V A+
Sbjct: 2136 LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2171
Score = 45.1 bits (105), Expect = 8e-05
Identities = 41/174 (23%), Positives = 71/174 (40%), Gaps = 19/174 (10%)
Query: 79 EGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYA 138
EG + +P P VSW+ +G+ V++ D M H + + VRA DAG Y
Sbjct: 14400 EGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRA-DAGIYT 14458
Query: 139 CVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPP----- 193
+N+ G AT ++ + V+ K + D K C+++ PP
Sbjct: 14459 ITLENKLGSATASINVKVIG----------LPGPCKDIKASDITKSSCKLTWEPPEFDGG 14508
Query: 194 -PKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
P L + T + +N +++ +KD+ ++ V AVN+ G
Sbjct: 14509 TPILHYVLERREAGRRTYIPVMSGEN--KLSWTVKDLIPNGEYFFRVKAVNKVG 14560
Score = 45.1 bits (105), Expect = 8e-05
Identities = 24/86 (27%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Query: 175 KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDA 234
K G SVKL IS P P + W ++++ +Q T+ + ++ T ++LIKD ++ ++
Sbjct: 26883 KYRAGTSVKLRAGISGKPAPTIEWYKDDKELQ--TNALVCVENTTDLASILIKDADRLNS 26940
Query: 235 GWYTVSAVNEAGVTTCNTRLDVTARP 260
G Y + N G + R+ + +P
Sbjct: 26941 GCYELKLRNAMGSASATIRVQILDKP 26966
Score = 44.3 bits (103), Expect = 1e-04
Identities = 52/193 (26%), Positives = 79/193 (40%), Gaps = 18/193 (9%)
Query: 67 RFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIF 126
+F+ E+ ++ EG ++S V W+ N + + +I SE H L
Sbjct: 11575 KFMSPLEDQTVKEGETATFVCELSH-EKMHVVWFKNDAKLHTSRT-VLISSEGKTHKLEM 11632
Query: 127 EVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLEC 186
+ V D K E + T QL VL + P F K K +E D + L+C
Sbjct: 11633 KEVTLDDISQIKAQVK----ELSSTAQLKVLEAD----PYFTVKLHDKTAVEKDEITLKC 11684
Query: 187 QISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
++S P K F K E+V + + S+ D R+ L IK + KD G Y V + G
Sbjct: 11685 EVSKDVPVKWF-KDGEEIVP--SPKYSIKADGLRRI-LKIKKADLKDKGEY----VCDCG 11736
Query: 247 VTTCNTRLDVTAR 259
+ V AR
Sbjct: 11737 TDKTKANVTVEAR 11749
Score = 44.3 bits (103), Expect = 1e-04
Identities = 27/101 (26%), Positives = 43/101 (42%), Gaps = 4/101 (3%)
Query: 60 QEKFYPPRF---IQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIV 116
QEK PP +++ E + + G R + G+P P W +G +++D+ H +
Sbjct: 17502 QEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDE-HYTVE 17560
Query: 117 SEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
++ L + D G Y N AG T V L VL
Sbjct: 17561 TDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVL 17601
Score = 44.3 bits (103), Expect = 1e-04
Identities = 36/144 (25%), Positives = 67/144 (46%), Gaps = 4/144 (2%)
Query: 119 KGLHSLIFEVVRASDAGAYACVAKNRAGEAT-FTVQLDVLAKEHKRAPMFIYKPQSKKVL 177
K L ++I + + + + VA N G + ++ + ++AK+ P S V
Sbjct: 23184 KSLQAVITNLTQGEEY-LFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQ 23242
Query: 178 EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
G +K+E IS P P + W ++ ++ T RI++ D+ TL IK+ +K D G Y
Sbjct: 23243 VGQDLKIEVPISGRPKPTITWTKDGLPLK-QTTRINV-TDSLDLTTLSIKETHKDDGGQY 23300
Query: 238 TVSAVNEAGVTTCNTRLDVTARPN 261
++ N G T + + +P+
Sbjct: 23301 GITVANVVGQKTASIEIVTLDKPD 23324
Score = 43.9 bits (102), Expect = 2e-04
Identities = 27/106 (25%), Positives = 53/106 (50%), Gaps = 2/106 (1%)
Query: 155 DVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISL 214
+V+AK+ P + V+EG+ + + A+P P + W ++ + V+ +DR+++
Sbjct: 14377 NVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVK-ASDRLTM 14435
Query: 215 YQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARP 260
D+ + K V + DAG YT++ N+ G T + + V P
Sbjct: 14436 KNDHISAHLEVPKSV-RADAGIYTITLENKLGSATASINVKVIGLP 14480
Score = 43.9 bits (102), Expect = 2e-04
Identities = 44/180 (24%), Positives = 77/180 (42%), Gaps = 19/180 (10%)
Query: 137 YACVAKNRAGEATFTVQLD----VLAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQIS 189
+ +A+N AG F+ D + A++ AP P+ K V+ G++ LE I
Sbjct: 24675 FRVIARNAAGN--FSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIR 24732
Query: 190 AIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTT 249
P P + W ++ + ++ R+ + + + TL++KD + D G Y + N G +
Sbjct: 24733 GKPIPDVVWSKDGKELEETAARMEI-KSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKS 24791
Query: 250 CNTRLDVTARPNQTLPAPKQLRVRPTFSK--YLA----LNGKGLNVKQAFNPEGEFQRLA 303
+ V RP P L+V ++ YLA L G N+ + E RL+
Sbjct: 24792 IPITVKVLDRPG---PPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS 24848
Score = 43.1 bits (100), Expect = 3e-04
Identities = 51/200 (25%), Positives = 85/200 (42%), Gaps = 25/200 (12%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P F++ E+ ++ E ++S A +V WY NGR ++ +K + +H L
Sbjct: 12822 PTEFVEHLEDQTVTEFDDAVFSCQLSREKA-NVKWYRNGREIKEGKKYKF-EKDGSIHRL 12879
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL---EGDS 181
I + R D YAC ++R A V + + E R P I + V+ E +
Sbjct: 12880 IIKDCRLDDECEYACGVEDRKSRARLFV--EEIPVEIIRPPQDILEAPGADVVFLAELNK 12937
Query: 182 VKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV-TLLIKDVNKKDAGWYTVS 240
K+E Q W RNN MV D+ + + G++ L I D+ +D G Y
Sbjct: 12938 DKVEVQ----------WLRNN-MVVVQGDKHQMMSE--GKIHRLQICDIKPRDQGEYRFI 12984
Query: 241 AVNEAGVTTCNTRLDVTARP 260
A ++ +L++ A P
Sbjct: 12985 AKDK----EARAKLELAAAP 13000
Score = 43.1 bits (100), Expect = 3e-04
Identities = 32/135 (23%), Positives = 64/135 (47%), Gaps = 6/135 (4%)
Query: 115 IVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK 174
I + KGL ++ + + + +A N AG + V+ KE P + +
Sbjct: 21014 ITTVKGLECVVRNLTEGEEY-TFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQ 21072
Query: 175 KVL---EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNK 231
K++ GD++K+E + P P + WK+ +++++ T R++ T + L I + +
Sbjct: 21073 KLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILK-QTQRVNFETTATSTI-LNINECVR 21130
Query: 232 KDAGWYTVSAVNEAG 246
D+G Y ++A N G
Sbjct: 21131 SDSGPYPLTARNIVG 21145
Score = 42.4 bits (98), Expect = 5e-04
Identities = 29/102 (28%), Positives = 50/102 (49%), Gaps = 10/102 (9%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYL-------NGRTVQSD-DLHKMIVS 117
P I + E M ++EG + K+ G+P P ++W+ N V D ++K++V
Sbjct: 16117 PPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD 16176
Query: 118 EKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
+ +L+ R SD G Y A N G A+ ++L+VL +
Sbjct: 16177 D--TCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGR 16216
Score = 42.0 bits (97), Expect = 7e-04
Identities = 34/128 (26%), Positives = 56/128 (43%), Gaps = 8/128 (6%)
Query: 141 AKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK---KVLEGDSVKLECQISAIPPPKLF 197
A N AGE V E + P K +++ G ++++ ++ P P
Sbjct: 15078 AVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKV 15137
Query: 198 WKRNNEMVQFNTDRISLYQDNTG-RVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
W + E + + DR+ + DN G + L+IKD +KD G Y ++A N G R++V
Sbjct: 15138 WTK--EEGELDKDRVVI--DNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 15193
Query: 257 TARPNQTL 264
P L
Sbjct: 15194 FDVPGPVL 15201
Score = 42.0 bits (97), Expect = 7e-04
Identities = 52/193 (26%), Positives = 78/193 (40%), Gaps = 23/193 (11%)
Query: 93 PAPDVSWYLNGRTVQSDDLHK---MIVSEKGLHSLIFEVVRASDAGAYA--CVAKNRAG- 146
P D L G V+ DL M + + F V + G Y AKN AG
Sbjct: 20297 PKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGA 20356
Query: 147 -----EATFTVQLDVLAKEHKRAPMFIYKPQSKKVLE---GDSVKLEC-QISAIPPPKLF 197
E+T T+ + K+ AP + P K L GD++ L I P PK
Sbjct: 20357 ISAPSESTETI----ICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSS 20412
Query: 198 WKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVT 257
W + + ++ +D + T + L IK +KDAG YT++A N G + ++ V
Sbjct: 20413 WSKAGKDIR-PSDITQITSTPTSSM-LTIKYATRKDAGEYTITATNPFGTKVEHVKVTVL 20470
Query: 258 ARPNQTLPAPKQL 270
P P P ++
Sbjct: 20471 DVPGP--PGPVEI 20481
Score = 42.0 bits (97), Expect = 7e-04
Identities = 28/99 (28%), Positives = 46/99 (46%), Gaps = 2/99 (2%)
Query: 59 IQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSE 118
+ K + P+ ++ + G + SG P P ++W G+ + ++ H ++
Sbjct: 31021 VPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQ-KGQDLIDNNGHYQVIVT 31079
Query: 119 KGLHSLIF-EVVRASDAGAYACVAKNRAGEATFTVQLDV 156
+ SL+F V DAG Y AKNR G TV+LDV
Sbjct: 31080 RSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 31118
Score = 41.2 bits (95), Expect = 0.001
Identities = 28/108 (25%), Positives = 48/108 (44%), Gaps = 2/108 (1%)
Query: 60 QEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEK 119
+E+ PP+ + +PE ++I G+ R++ V G P P W G H +
Sbjct: 18894 KEQLLPPKIL-MPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKAD 18951
Query: 120 GLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMF 167
LI + V D+G Y+ A+N +G T +++ V+ P F
Sbjct: 18952 SSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 18999
Score = 41.2 bits (95), Expect = 0.001
Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 6/102 (5%)
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V G +V L+ + P P + WK++ +++ Q N TL + VN+KD+G
Sbjct: 19307 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNL--CTLELFSVNRKDSG 19364
Query: 236 WYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFS 277
YT++A N +G + +L V +P P +++ +S
Sbjct: 19365 DYTITAENSSGSKSATIKLKVLDKPG----PPASVKINKMYS 19402
Score = 41.2 bits (95), Expect = 0.001
Identities = 39/150 (26%), Positives = 63/150 (42%), Gaps = 17/150 (11%)
Query: 47 STSRGDVNDQDAIQEKFYPPRFIQVP---ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNG 103
S S G + +D + PPR P + + + G ++D + G P P + W + G
Sbjct: 22526 SESTGAITARDEVD----PPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQW-IKG 22580
Query: 104 RTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKR 163
S+ I S SL + D+G Y AKN AGE + TV + VL +
Sbjct: 22581 DQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPG-- 22638
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPP 193
P+ V+ G + + +C ++ PP
Sbjct: 22639 ------PPEGPVVISGVTAE-KCTLAWKPP 22661
Score = 41.2 bits (95), Expect = 0.001
Identities = 21/86 (24%), Positives = 36/86 (41%)
Query: 171 PQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVN 230
P + EG + + C + P P++ W + ++ TL+I DV
Sbjct: 33335 PSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQ 33394
Query: 231 KKDAGWYTVSAVNEAGVTTCNTRLDV 256
K+D G YT+S NE G + + +
Sbjct: 33395 KQDGGLYTLSLGNEFGSDSATVNIHI 33420
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/204 (20%), Positives = 72/204 (35%), Gaps = 37/204 (18%)
Query: 90 SGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAG--- 146
S L A +V+WY +G+ ++ + + S G + L + SD G Y C G
Sbjct: 32742 SVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSK 32801
Query: 147 -------------------------------EATFTVQLDVLAKEH-KRAPMFIYKPQSK 174
E+T T + + A E P+ + Q
Sbjct: 32802 TNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDT 32861
Query: 175 KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDA 234
V K + + P P W ++ + + + L +D G L I + D+
Sbjct: 32862 TVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT-QGGKYKLSEDK-GGFFLEIHKTDTSDS 32919
Query: 235 GWYTVSAVNEAGVTTCNTRLDVTA 258
G YT + N AG + + +L + A
Sbjct: 32920 GLYTCTVKNSAGSVSSSCKLTIKA 32943
Score = 40.4 bits (93), Expect = 0.002
Identities = 30/129 (23%), Positives = 60/129 (46%), Gaps = 7/129 (5%)
Query: 137 YACVAKNRAGEATFTVQLD--VLAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQISAI 191
+ +AKN AG + + + ++ AP + K + G++ +LE +S
Sbjct: 21429 FRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGR 21488
Query: 192 PPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCN 251
PPP + W ++ + ++ T ++ + + L+ KD ++D+G YT++A N G
Sbjct: 21489 PPPTMEWSKDGKELE-GTAKLEIKIADFS-TNLVNKDSTRRDSGAYTLTATNPGGFAKHI 21546
Query: 252 TRLDVTARP 260
+ V RP
Sbjct: 21547 FNVKVLDRP 21555
Score = 40.4 bits (93), Expect = 0.002
Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Query: 152 VQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDR 211
+ + V+AK+ P F + VL G+ +K++ P P + W ++N ++ T R
Sbjct: 22135 LSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLK-QTTR 22193
Query: 212 ISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
++ + L IKD ++D G Y V N AG
Sbjct: 22194 VNA-ESTENNSLLTIKDACREDVGHYVVKLTNSAG 22227
Score = 40.4 bits (93), Expect = 0.002
Identities = 21/86 (24%), Positives = 38/86 (44%), Gaps = 1/86 (1%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 132
++ ++ + K +G P P W +G+ + +K+ +KG L S
Sbjct: 32859 QDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS-EDKGGFFLEIHKTDTS 32917
Query: 133 DAGAYACVAKNRAGEATFTVQLDVLA 158
D+G Y C KN AG + + +L + A
Sbjct: 32918 DSGLYTCTVKNSAGSVSSSCKLTIKA 32943
Score = 40.0 bits (92), Expect = 0.003
Identities = 39/163 (23%), Positives = 66/163 (40%), Gaps = 16/163 (9%)
Query: 97 VSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDV 156
V W+ N + + + M E HS+ F+ + D A + EA TV
Sbjct: 11959 VKWFKNDQRLHTTRSVSM-QDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVL--- 12014
Query: 157 LAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQ 216
+ P F K Q +E D V L+C+IS P ++K E+ + ++ +
Sbjct: 12015 -----EGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEI---KPSKNAVIK 12066
Query: 217 DNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 259
+ + L++K K D G YT + G + +LD+ R
Sbjct: 12067 ADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDIEDR 12105
Score = 40.0 bits (92), Expect = 0.003
Identities = 32/142 (22%), Positives = 62/142 (43%), Gaps = 14/142 (9%)
Query: 122 HSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL---E 178
H F V+ + AG ++ +++ + A++ P P+ K +
Sbjct: 22507 HRYEFRVIARNAAGVFSEPSESTGA---------ITARDEVDPPRISMDPKYKDTIVVHA 22557
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G+S K++ I P P + W + ++ + NT R+ + + +L +KD + D+G Y
Sbjct: 22558 GESFKVDADIYGKPIPTIQWIKGDQELS-NTARLEIKSTDFA-TSLSVKDAVRVDSGNYI 22615
Query: 239 VSAVNEAGVTTCNTRLDVTARP 260
+ A N AG + + V RP
Sbjct: 22616 LKAKNVAGERSVTVNVKVLDRP 22637
Score = 40.0 bits (92), Expect = 0.003
Identities = 30/129 (23%), Positives = 58/129 (44%), Gaps = 7/129 (5%)
Query: 137 YACVAKNRAGEATFTVQLD--VLAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQISAI 191
+ +AKN AG + + AK+ P P+ + + G++ +LE +
Sbjct: 23593 FRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGK 23652
Query: 192 PPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCN 251
P P + W R ++ ++ + R + ++ + L++KD + D G Y + A N AG +
Sbjct: 23653 PLPTIEWLRGDKEIE-ESARCEI-KNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFP 23710
Query: 252 TRLDVTARP 260
+ V RP
Sbjct: 23711 VNVKVLDRP 23719
Score = 40.0 bits (92), Expect = 0.003
Identities = 24/98 (24%), Positives = 41/98 (41%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F ++ N EG+ + +VSG+P P + W +G+ + ++I ++L
Sbjct: 31795 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 31854
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKR 163
D G Y A N AG + L V +K+
Sbjct: 31855 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 31892
Score = 39.7 bits (91), Expect = 0.004
Identities = 40/158 (25%), Positives = 61/158 (38%), Gaps = 13/158 (8%)
Query: 93 PAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTV 152
P V W + + +Q D K I EK +H L+ R SDAG Y VA A V
Sbjct: 3084 PDITVQWMKDDQELQITDRIK-IQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFV 3142
Query: 153 Q-LDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDR 211
+ DV + K+ I K ++ E + ++ W ++ + F
Sbjct: 3143 EGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAH----------WYKDGIEINFQVQE 3192
Query: 212 ISLYQDNTGRVTLLIKDVNKKDAGWYT-VSAVNEAGVT 248
Y + I + + DAG YT V+ N + VT
Sbjct: 3193 RHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVT 3230
Score = 39.7 bits (91), Expect = 0.004
Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 2/82 (2%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G ++++ ++ P P + W + +++ R+ L QD RV L IK+ + D G Y
Sbjct: 17923 GQTIRILARVKGRPEPDITWTKEGKVL-VREKRVDLIQD-LPRVELQIKEAVRADHGKYI 17980
Query: 239 VSAVNEAGVTTCNTRLDVTARP 260
+SA N +G + ++V RP
Sbjct: 17981 ISAKNSSGHAQGSAIVNVLDRP 18002
Score = 39.7 bits (91), Expect = 0.004
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 1/76 (1%)
Query: 84 RMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKN 143
R+ + G PAP VSW G + D + S +LI + SDAG Y KN
Sbjct: 20001 RLKIPIKGKPAPSVSWK-KGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKN 20059
Query: 144 RAGEATFTVQLDVLAK 159
AG T+ + V+ K
Sbjct: 20060 VAGTKEGTISIKVVGK 20075
Score = 39.7 bits (91), Expect = 0.004
Identities = 21/91 (23%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 69 IQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEV 128
++ E + G ++ +SG PAP + WY + + +Q++ L + + L S++ +
Sbjct: 26876 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNAL-VCVENTTDLASILIKD 26934
Query: 129 VRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
++G Y +N G A+ T+++ +L K
Sbjct: 26935 ADRLNSGCYELKLRNAMGSASATIRVQILDK 26965
Score = 39.7 bits (91), Expect = 0.004
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKD-VNKKDAGWY 237
G S++L +S PPP + W + + + I D T +LLI D VN+ DAG Y
Sbjct: 29461 GASLRLMVSVSGRPPPVITWSKQG--IDLASRAII---DTTESYSLLIVDKVNRYDAGKY 29515
Query: 238 TVSAVNEAGVTTCNTRLDVTARP 260
T+ A N++G + + V P
Sbjct: 29516 TIEAENQSGKKSATVLVKVYDTP 29538
Score = 39.3 bits (90), Expect = 0.005
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 2/85 (2%)
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V G ++L ++ P PK+ W + +M+ RI++ ++ + T+ I D + D G
Sbjct: 13702 VKAGTKIELPATVTGKPEPKITWTKA-DMILKQDKRITI-ENVPKKSTVTIVDSKRSDTG 13759
Query: 236 WYTVSAVNEAGVTTCNTRLDVTARP 260
Y + AVN G T ++V +P
Sbjct: 13760 TYIIEAVNVCGRATAVVEVNVLDKP 13784
Score = 39.3 bits (90), Expect = 0.005
Identities = 36/140 (25%), Positives = 63/140 (45%), Gaps = 12/140 (8%)
Query: 137 YACVAKNRAGEATFT-VQLDVLAKEHKRAPMFIYKP---QSKKVLEGDSVKLECQISAIP 192
+ +A N AGE+ V VL K+ P I + + + GD+++L I +P
Sbjct: 17187 FRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVP 17246
Query: 193 PPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
PK+ WK+ + RI + + L I++ +D G Y+++ N AG T +
Sbjct: 17247 FPKVTWKKEDRDAPTKA-RIDVTPVGS---KLEIRNAAHEDGGIYSLTVENPAGSKTVSV 17302
Query: 253 RLDVTARPNQTLPAPKQLRV 272
++ V +P P+ L V
Sbjct: 17303 KVLVLDKPG----PPRDLEV 17318
Score = 39.3 bits (90), Expect = 0.005
Identities = 37/128 (28%), Positives = 62/128 (48%), Gaps = 14/128 (10%)
Query: 141 AKNRAGEAT-FTVQLDVLAKEHKRAP---MFIYKPQSKKVLEGDSVKLECQISAIPPPKL 196
A+N+AG + + L VL KE P M + + V G ++K++ IS P PK+
Sbjct: 26449 AENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKV 26508
Query: 197 FWKRNN----EMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
R+ ++FNT+ + +N +T+ +K+ DAG Y ++A N +G T
Sbjct: 26509 TLSRDGVPLKATMRFNTE---ITAEN---LTINLKESVTADAGRYEITAANSSGTTKAFI 26562
Query: 253 RLDVTARP 260
+ V RP
Sbjct: 26563 NIVVLDRP 26570
Score = 38.9 bits (89), Expect = 0.006
Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Query: 75 MSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDA 134
+++ G+ R+ +V G P PD++W G+ + + +I + I E VRA D
Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA-DH 17976
Query: 135 GAYACVAKNRAGEATFTVQLDVL 157
G Y AKN +G A + ++VL
Sbjct: 17977 GKYIISAKNSSGHAQGSAIVNVL 17999
Score = 38.9 bits (89), Expect = 0.006
Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
Query: 85 MDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNR 144
+D +SG PAP V+W L ++ D I + K +L + D+G Y +N
Sbjct: 28667 IDVPISGRPAPKVTWKLEEMRLKETD-RVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 28725
Query: 145 AGEATFTVQLDVLAK 159
AG TF+V + V+ +
Sbjct: 28726 AGVKTFSVTVVVIGR 28740
Score = 38.5 bits (88), Expect = 0.008
Identities = 42/153 (27%), Positives = 60/153 (39%), Gaps = 16/153 (10%)
Query: 92 LPAPDV--SWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEAT 149
L PDV W L G+ + + ++I K H LI + G + A N A
Sbjct: 11774 LSEPDVHGQWKLKGQPLTASPDCEIIEDGKK-HILILHNCQLGMTGEVSFQAANAKSAAN 11832
Query: 150 FTVQLDVLAKEHKRAPMFIYKPQSK-KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFN 208
V K P+ P S KV E D K EC++S P + K E+
Sbjct: 11833 LKV---------KELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEIT--G 11881
Query: 209 TDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSA 241
DR L +D T + +++IK +D Y A
Sbjct: 11882 DDRFELIKDGT-KHSMVIKSAAFEDEAKYMFEA 11913
Score = 38.5 bits (88), Expect = 0.008
Identities = 26/138 (18%), Positives = 62/138 (44%), Gaps = 9/138 (6%)
Query: 133 DAGAYACVAKNRAGEATFTVQLD--VLAKEHKRAPMFIYKPQ---SKKVLEGDSVKLECQ 187
D + +A+N G + Q ++ ++ P+ + P+ + G+S++++
Sbjct: 27922 DRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKAL 27981
Query: 188 ISAIPPPKLFWKRNNEMVQFNTDRISL-YQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
+ P P++ W ++ ++ R+++ D G +L ++D + G YTV A N +G
Sbjct: 27982 VQGRPVPRVTWFKDGVEIE---KRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASG 28038
Query: 247 VTTCNTRLDVTARPNQTL 264
++ V P + +
Sbjct: 28039 SAKAEIKVKVQDTPGKVV 28056
Score = 38.5 bits (88), Expect = 0.008
Identities = 21/82 (25%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G + L+ + P PK+ W + ++ + +++SL Q R T +IK ++ D+G YT
Sbjct: 29062 GSDLVLDAAVGGKPEPKIIWTKGDKELDL-CEKVSL-QYTGKRATAVIKFCDRSDSGKYT 29119
Query: 239 VSAVNEAGVTTCNTRLDVTARP 260
++ N +G + + V P
Sbjct: 29120 LTVKNASGTKAVSVMVKVLDSP 29141
Score = 38.5 bits (88), Expect = 0.008
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 132
+ ++I G R+ VSG P P ++W G + S +I + + LI + V
Sbjct: 29454 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLAS---RAIIDTTESYSLLIVDKVNRY 29510
Query: 133 DAGAYACVAKNRAGEATFTVQLDV 156
DAG Y A+N++G+ + TV + V
Sbjct: 29511 DAGKYTIEAENQSGKKSATVLVKV 29534
Score = 38.1 bits (87), Expect = 0.010
Identities = 29/115 (25%), Positives = 42/115 (36%), Gaps = 12/115 (10%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
A + KP+S V EG+S + C P P + W R +++ +T + T
Sbjct: 32560 AARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVL--STSARHQVTTTKYKST 32617
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCN----------TRLDVTARPNQTLPAPK 268
I V D G Y+V N G T VT+ P P P+
Sbjct: 32618 FEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPR 32672
Score = 37.7 bits (86), Expect = 0.013
Identities = 24/69 (34%), Positives = 37/69 (53%), Gaps = 4/69 (5%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLL-IKDVNKKDAGWY 237
G +++L + PPPK+ W + N ++ DRI L +T T L ++VNK DAG Y
Sbjct: 19708 GVTMRLYVPVKGRPPPKITWSKPNVNLR---DRIGLDIKSTDFDTFLRCENVNKYDAGKY 19764
Query: 238 TVSAVNEAG 246
++ N G
Sbjct: 19765 ILTLENSCG 19773
Score = 37.7 bits (86), Expect = 0.013
Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 11/92 (11%)
Query: 157 LAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTD-RI 212
+AKE + P+F + +K L G S + P P + W + + TD R
Sbjct: 26176 IAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPD------TDLRT 26229
Query: 213 SLYQDNT-GRVTLLIKDVNKKDAGWYTVSAVN 243
Y D T R +L I++ N+ D+G YT++ N
Sbjct: 26230 RAYVDTTDSRTSLTIENANRNDSGKYTLTIQN 26261
Score = 37.4 bits (85), Expect = 0.017
Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 3/99 (3%)
Query: 64 YPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ-SDDLHKMIVSEKGLH 122
+ PR + + G+ R V P +V WY NG +Q S +H + G+
Sbjct: 32372 HAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIH--YTNTSGVL 32429
Query: 123 SLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEH 161
+L D+G Y V N GEA+ LDV ++
Sbjct: 32430 TLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDY 32468
Score = 37.0 bits (84), Expect = 0.023
Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
Query: 69 IQVPENM-SIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI-F 126
+++P N SI G +++ V G P P++SW +G ++ ++ V E +++
Sbjct: 24314 LKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTT--RVNVEETATSTVLHI 24371
Query: 127 EVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
+ D G Y A N AG AT + + VL K
Sbjct: 24372 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 24404
Score = 37.0 bits (84), Expect = 0.023
Identities = 28/120 (23%), Positives = 54/120 (45%), Gaps = 8/120 (6%)
Query: 43 VRSRSTSRGDVNDQDAIQEKFYPPRF---IQVPENMSIDEGRFCRMDFKVSGLPAPDVSW 99
V S S G + +D ++ PPR ++ + + + G +++ ++G P P +SW
Sbjct: 25768 VSEPSESTGPIIVKDDVE----PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISW 25823
Query: 100 YLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
+G ++ ++I ++ + + +R D G Y KN AG + V VL K
Sbjct: 25824 AKDGIEIEERARTEIISTDNHTLLTVKDCIR-RDTGQYVLTLKNVAGTRSVAVNCKVLDK 25882
Score = 36.6 bits (83), Expect = 0.030
Identities = 38/139 (27%), Positives = 63/139 (45%), Gaps = 15/139 (10%)
Query: 141 AKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQISAIPPPKLF 197
A N AG V DV E + AP F + ++ L G S+++ I P P++
Sbjct: 20750 AINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVT 20809
Query: 198 WKRNNEMVQFNTDRISLYQDNTGRVTLL-IKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
W ++N ++ +R ++ +NT TLL I + N+ D G + ++ N AG + + V
Sbjct: 20810 WTKDNINLK---NRANI--ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRV 20864
Query: 257 TARPNQTLPAPKQLRVRPT 275
P L +RPT
Sbjct: 20865 LDTPGPV------LNLRPT 20877
Score = 36.6 bits (83), Expect = 0.030
Identities = 30/132 (22%), Positives = 55/132 (41%), Gaps = 5/132 (3%)
Query: 163 RAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV 222
+AP F + ++ V + L C+++ P P + W R + + + + + + G
Sbjct: 30926 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 30985
Query: 223 TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLAL 282
L+I V DA Y V A N+ G + L+V LP + AL
Sbjct: 30986 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLP-----KTLEGMGAVHAL 31040
Query: 283 NGKGLNVKQAFN 294
G+ +++K F+
Sbjct: 31041 RGEVVSIKIPFS 31052
Score = 35.8 bits (81), Expect = 0.051
Identities = 30/120 (25%), Positives = 56/120 (46%), Gaps = 12/120 (10%)
Query: 47 STSRGDVNDQDAIQEKFYPPRFIQV--PENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGR 104
S + G++ D IQE+ P FI + + + G R+ + G P P SW +G+
Sbjct: 15793 SDTTGEIPATD-IQEE--PEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGK 15849
Query: 105 TVQS--DDLHKM-----IVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
++ D +H + + + + +I + S G Y+ AKN+AG+ T ++ V+
Sbjct: 15850 AKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVM 15909
Score = 35.8 bits (81), Expect = 0.051
Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 5/95 (5%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P + + ++I G + + SG P P VSW+ + V DD + + +L
Sbjct: 16818 PTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPA---TL 16874
Query: 125 IFEVVRA--SDAGAYACVAKNRAGEATFTVQLDVL 157
E ++A SD+G Y V +N G Q++V+
Sbjct: 16875 ALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVV 16909
Score = 35.8 bits (81), Expect = 0.051
Identities = 22/84 (26%), Positives = 36/84 (42%), Gaps = 1/84 (1%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 132
+ + I G R+ V G P P V+W+ +G ++ ++ I G SL
Sbjct: 27966 DGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEK-RMNMEITDVLGSTSLFVRDATRD 28024
Query: 133 DAGAYACVAKNRAGEATFTVQLDV 156
G Y AKN +G A +++ V
Sbjct: 28025 HRGVYTVEAKNASGSAKAEIKVKV 28048
Score = 35.4 bits (80), Expect = 0.066
Identities = 24/100 (24%), Positives = 44/100 (44%), Gaps = 10/100 (10%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT------LLIKDVNKK 232
G +++ I P PK W+ + + + D + ++ T ++I + +
Sbjct: 15825 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 15884
Query: 233 DAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRV 272
G Y+++A N+AG T N R+ V P PK L+V
Sbjct: 15885 HTGKYSITAKNKAGQKTANCRVKVMDVPG----PPKDLKV 15920
Score = 35.4 bits (80), Expect = 0.066
Identities = 42/166 (25%), Positives = 70/166 (42%), Gaps = 16/166 (9%)
Query: 114 MIVSEKGLHSLIFEVVRASDAGAY--ACVAKNRAGEATFT-VQLDVLAKEHKRAPMFIYK 170
M G++ EV + + Y A N+AG V ++ +E AP
Sbjct: 22886 MCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLD 22945
Query: 171 PQSKKVLE---GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIK 227
+ +K++ G S++L I P P++ W + + + R + D T T L+
Sbjct: 22946 LELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEI-----RDAAIIDVTSSFTSLVL 23000
Query: 228 D-VNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRV 272
D VN+ D+G YT++ N +G + VT R T P L+V
Sbjct: 23001 DNVNRYDSGKYTLTLENSSGTKSA----FVTVRVLDTPSPPVNLKV 23042
Score = 35.4 bits (80), Expect = 0.066
Identities = 25/110 (22%), Positives = 50/110 (45%), Gaps = 2/110 (1%)
Query: 156 VLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLY 215
V+A++ + P + V + +K++ P + W+++ + ++ T R+++
Sbjct: 25386 VIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLK-ETTRVNVS 25444
Query: 216 QDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLP 265
T +L IK+ +K+D G Y + N AG T + V RP P
Sbjct: 25445 SSKTV-TSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGP 25493
Score = 35.4 bits (80), Expect = 0.066
Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 1/85 (1%)
Query: 84 RMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKN 143
++D G P V+W +G+T++ + + S K + SL + D G Y N
Sbjct: 25413 KIDVPFKGRPQATVNWRKDGQTLK-ETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSN 25471
Query: 144 RAGEATFTVQLDVLAKEHKRAPMFI 168
AG T + + VL + P+ I
Sbjct: 25472 SAGSITVPITIIVLDRPGPPGPIRI 25496
Score = 35.4 bits (80), Expect = 0.066
Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP + +S +V G + + + + P ++ W N +Q + +I Y + +G +T
Sbjct: 32373 APRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQ-ESSKIH-YTNTSGVLT 32430
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVT 257
L I D + D+G Y N G + LDVT
Sbjct: 32431 LEILDCHTDDSGTYRAVCTNYKGEASDYATLDVT 32464
Score = 35.0 bits (79), Expect = 0.086
Identities = 26/114 (22%), Positives = 50/114 (43%), Gaps = 8/114 (7%)
Query: 47 STSRGDVNDQDAIQEKFYPPRFIQVP---ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNG 103
S S G + +D ++ PR P + + ++ G R++ V G P P + W
Sbjct: 23608 SDSTGPITAKDEVEL----PRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGD 23663
Query: 104 RTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
+ ++ ++ ++ ++ + +R D G Y A N AG +F V + VL
Sbjct: 23664 KEIEESARCEIKNTDFKALLIVKDAIRI-DGGQYILRASNVAGSKSFPVNVKVL 23716
Score = 34.7 bits (78), Expect = 0.11
Identities = 22/104 (21%), Positives = 44/104 (42%), Gaps = 5/104 (4%)
Query: 56 QDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMI 115
+D + E P F + S+ G+ +++ +SG P P ++W +G ++ +
Sbjct: 23224 KDLVIEPDVKPAF----SSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLK-QTTRINV 23278
Query: 116 VSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
L +L + D G Y N G+ T ++++ L K
Sbjct: 23279 TDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK 23322
Score = 34.3 bits (77), Expect = 0.15
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 3/69 (4%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGL-HSLIFEVVRA 131
+++++ EG ++ KVS V WYLN ++ DD + IV KG L+ A
Sbjct: 2452 KDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIV--KGTKQRLVINRTHA 2509
Query: 132 SDAGAYACV 140
SD G Y +
Sbjct: 2510 SDEGPYKLI 2518
Score = 34.3 bits (77), Expect = 0.15
Identities = 27/126 (21%), Positives = 55/126 (43%), Gaps = 12/126 (9%)
Query: 69 IQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEV 128
++ + + + G R++ VSG P P + W +G+ ++ ++ +++ +L+ +
Sbjct: 21465 VKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKD 21523
Query: 129 VRASDAGAYACVAKNRAGEATFTVQLDVLAKE-HKRAPMFIYKPQSKKVLEGDSVKLECQ 187
D+GAY A N G A + VL + P+ + + S+K C
Sbjct: 21524 STRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEK----------CV 21573
Query: 188 ISAIPP 193
+S PP
Sbjct: 21574 LSWFPP 21579
Score = 34.3 bits (77), Expect = 0.15
Identities = 20/85 (23%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V G+ +K+ I+ P P + W ++ ++ + DN L +KD ++D G
Sbjct: 25801 VKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDN--HTLLTVKDCIRRDTG 25858
Query: 236 WYTVSAVNEAGVTTCNTRLDVTARP 260
Y ++ N AG + V +P
Sbjct: 25859 QYVLTLKNVAGTRSVAVNCKVLDKP 25883
Score = 33.9 bits (76), Expect = 0.19
Identities = 22/94 (23%), Positives = 37/94 (39%), Gaps = 4/94 (4%)
Query: 172 QSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNK 231
Q+ V G S++L P P W + + + D TL +++ N+
Sbjct: 28365 QTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRAD----IHTTDSFSTLTVENCNR 28420
Query: 232 KDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLP 265
DAG YT++ N +G + + V P P
Sbjct: 28421 NDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGP 28454
Score = 33.5 bits (75), Expect = 0.25
Identities = 36/159 (22%), Positives = 62/159 (38%), Gaps = 16/159 (10%)
Query: 14 VFQAQDDSGAQDSQQHNSEHARLQVP------TSQVRSRSTSRGDVNDQDAIQEKFYPPR 67
V +A D+ + + N + R +V Q R + ++ +D + +K YP
Sbjct: 19627 VKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKD 19686
Query: 68 FIQVPEN---------MSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSE 118
+ PE + + G R+ V G P P ++W ++ D + I S
Sbjct: 19687 ILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLR-DRIGLDIKST 19745
Query: 119 KGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
L E V DAG Y +N G+ +T+ + VL
Sbjct: 19746 DFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVL 19784
Score = 33.1 bits (74), Expect = 0.33
Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V G +V+ I +P P W + ++ + + ++ DN V L IK+ ++D G
Sbjct: 17522 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTD-EHYTVETDNFSSV-LTIKNCLRRDTG 17579
Query: 236 WYTVSAVNEAGVTTCNTRLDVTARP 260
Y ++ N AG T L V P
Sbjct: 17580 EYQITVSNAAGSKTVAVHLTVLDVP 17604
Score = 33.1 bits (74), Expect = 0.33
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 1/95 (1%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP F + ++ G ++D G P P V+W+ + ++ +E
Sbjct: 22147 PPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLT 22206
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
I + R D G Y N AGEA T+ + VL K
Sbjct: 22207 IKDACR-EDVGHYVVKLTNSAGEAIETLNVIVLDK 22240
Score = 32.7 bits (73), Expect = 0.43
Identities = 26/104 (25%), Positives = 44/104 (42%), Gaps = 6/104 (5%)
Query: 59 IQEKFYPPRFI---QVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMI 115
++++ PP I + I G R+ + G+P P V+W R + ++
Sbjct: 17209 VKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTK--ARID 17266
Query: 116 VSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
V+ G L D G Y+ +N AG T +V++ VL K
Sbjct: 17267 VTPVG-SKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDK 17309
Score = 32.7 bits (73), Expect = 0.43
Identities = 22/95 (23%), Positives = 38/95 (40%), Gaps = 7/95 (7%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P + I VP GR + ++G P P SW+ G ++ + + + + L
Sbjct: 29744 PQKTIHVPA------GRPVELVIPIAGRPPPAASWFFAGSKLRESE-RVTVETHTKVAKL 29796
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
D G Y KN G + T+++ +L K
Sbjct: 29797 TIRETTIRDTGEYTLELKNVTGTTSETIKVIILDK 29831
Score = 32.0 bits (71), Expect = 0.73
Identities = 30/134 (22%), Positives = 44/134 (32%), Gaps = 9/134 (6%)
Query: 32 EHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYPP----RFIQVPENMSIDEGRFCRMDF 87
EH + V S + IQ+ PP R + + + G +
Sbjct: 15361 EHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPA 15420
Query: 88 KVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS-----LIFEVVRASDAGAYACVAK 142
V+GLP P + W N ++ I E+ S L D G Y A
Sbjct: 15421 DVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTAS 15480
Query: 143 NRAGEATFTVQLDV 156
NR G V ++V
Sbjct: 15481 NRLGSVFRNVHVEV 15494
Score = 32.0 bits (71), Expect = 0.73
Identities = 33/126 (26%), Positives = 58/126 (46%), Gaps = 8/126 (6%)
Query: 181 SVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIK-DVNKKDAGWYTV 239
+++L I P P++ W R++ + D+ S+ ++T TLLI +VN+ D+G Y +
Sbjct: 21877 TLRLFVPIKGRPAPEVKWARDHGE---SLDKASI--ESTSSYTLLIVGNVNRFDSGKYIL 21931
Query: 240 SAVNEAGVTTC--NTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGLNVKQAFNPEG 297
+ N +G + N R+ T P Q L + + T + L G +K +
Sbjct: 21932 TVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKR 21991
Query: 298 EFQRLA 303
E R A
Sbjct: 21992 ESTRKA 21997
Score = 31.6 bits (70), Expect = 0.96
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 89 VSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEA 148
+ G P P SW G+ ++ D+ I S L + DAG Y A N G
Sbjct: 20403 ILGKPLPKSSWSKAGKDIRPSDI-TQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTK 20461
Query: 149 TFTVQLDVLAKEHKRAPMFIYKPQSKK 175
V++ VL P+ I ++K
Sbjct: 20462 VEHVKVTVLDVPGPPGPVEISNVSAEK 20488
Score = 31.6 bits (70), Expect = 0.96
Identities = 26/109 (23%), Positives = 46/109 (42%), Gaps = 6/109 (5%)
Query: 52 DVNDQDAIQEKFYPPRF---IQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQS 108
DV ++EK P +++ + ++I G R+ + G P P+V W G+
Sbjct: 22926 DVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKW---GKVDGE 22982
Query: 109 DDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
+I SL+ + V D+G Y +N +G + V + VL
Sbjct: 22983 IRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVL 23031
Score = 31.6 bits (70), Expect = 0.96
Identities = 20/82 (24%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G V+L I+ PPP W ++ ++R+++ + +T L I++ +D G YT
Sbjct: 29753 GRPVELVIPIAGRPPPAASWFFAGSKLR-ESERVTV-ETHTKVAKLTIRETTIRDTGEYT 29810
Query: 239 VSAVNEAGVTTCNTRLDVTARP 260
+ N G T+ ++ + +P
Sbjct: 29811 LELKNVTGTTSETIKVIILDKP 29832
Score = 30.8 bits (68), Expect = 1.6
Identities = 23/87 (26%), Positives = 37/87 (42%), Gaps = 14/87 (16%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT-----LLIKDVNKKD 233
G +++ +S PPP + W N +L Q+ T T ++IK+ +
Sbjct: 16539 GGVIRIIAYVSGKPPPTVTWNMNER---------TLPQEATIETTAISSSMVIKNCQRSH 16589
Query: 234 AGWYTVSAVNEAGVTTCNTRLDVTARP 260
G Y++ A NEAG +DV P
Sbjct: 16590 QGVYSLLAKNEAGERKKTIIVDVLDVP 16616
Score = 30.4 bits (67), Expect = 2.1
Identities = 24/105 (22%), Positives = 43/105 (40%), Gaps = 13/105 (12%)
Query: 90 SGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEAT 149
+G P P +W + +++ D KM + L+ SD G Y +NR +
Sbjct: 13419 TGYPRPTATWCFGDKVLETGDRVKM-KTLSAYAELVISPSERSDKGIYTLKLENRVKTIS 13477
Query: 150 FTVQLDVLAKEHKRAPMFIYKPQSKKVLE-GDSVKLECQISAIPP 193
+ ++V+A +P + K L+ GD K ++ PP
Sbjct: 13478 GEIDVNVIA-----------RPSAPKELKFGDITKDSVHLTWEPP 13511
Score = 30.4 bits (67), Expect = 2.1
Identities = 25/113 (22%), Positives = 45/113 (39%), Gaps = 5/113 (4%)
Query: 47 STSRGDVNDQDAIQ--EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGR 104
S S G + +D I P++ V + + G ++ + G P PDV W +G+
Sbjct: 24690 SDSSGAITARDEIDAPNASLDPKYKDV---IVVHAGETFVLEADIRGKPIPDVVWSKDGK 24746
Query: 105 TVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
++ I S +L+ + +D G Y N G + + + VL
Sbjct: 24747 ELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVL 24799
Score = 30.0 bits (66), Expect = 2.8
Identities = 25/96 (26%), Positives = 48/96 (50%), Gaps = 7/96 (7%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLL-IKDVNKKDAGWY 237
G+ V++ PPP + W+++ + + + R S+ +NT +LL I V + D G Y
Sbjct: 27286 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSDA-RYSI--ENTDSSSLLTIPQVTRNDTGKY 27342
Query: 238 TVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVR 273
++ N G +T V+ + T A ++L+V+
Sbjct: 27343 ILTIENGVGEPKSST---VSVKVLDTPAACQKLQVK 27375
Score = 30.0 bits (66), Expect = 2.8
Identities = 16/61 (26%), Positives = 26/61 (42%), Gaps = 2/61 (3%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G +V LE P P + W ++ + + ++TL IK+ K+ G YT
Sbjct: 27578 GHNVHLELPYKGKPKPSISWLKDG--LPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT 27635
Query: 239 V 239
V
Sbjct: 27636 V 27636
Score = 29.6 bits (65), Expect = 3.6
Identities = 24/102 (23%), Positives = 42/102 (41%), Gaps = 8/102 (7%)
Query: 60 QEKFYPPRFIQVPENMSIDEGRFC---RMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIV 116
+++ PP + + R C R+ + G PAP+V W + + L K +
Sbjct: 21852 EDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARD----HGESLDKASI 21907
Query: 117 SEKGLHS-LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
++ LI V D+G Y +N +G + V + VL
Sbjct: 21908 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVL 21949
Score = 29.6 bits (65), Expect = 3.6
Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 3/84 (3%)
Query: 75 MSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL-IFEVVRASD 133
++I G +D V G P P + W + + D K+ + G + + + SD
Sbjct: 29057 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKEL--DLCEKVSLQYTGKRATAVIKFCDRSD 29114
Query: 134 AGAYACVAKNRAGEATFTVQLDVL 157
+G Y KN +G +V + VL
Sbjct: 29115 SGKYTLTVKNASGTKAVSVMVKVL 29138
Score = 29.3 bits (64), Expect = 4.7
Identities = 18/86 (20%), Positives = 37/86 (43%), Gaps = 4/86 (4%)
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V +G ++L I P P W + + + + ++ + L+IK+ ++ D+G
Sbjct: 30148 VRQGGVIRLTIPIKGKPFPICKWTKEGQDIS----KRAMIATSETHTELVIKEADRGDSG 30203
Query: 236 WYTVSAVNEAGVTTCNTRLDVTARPN 261
Y + N+ G ++ V PN
Sbjct: 30204 TYDLVLENKCGKKAVYIKVRVIGSPN 30229
Score = 28.9 bits (63), Expect = 6.2
Identities = 33/112 (29%), Positives = 44/112 (39%), Gaps = 26/112 (23%)
Query: 89 VSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI----FEVVRAS---DAGAYACVA 141
V G PAP V+W R V D+ V KG L+ F V+ S D+G Y+
Sbjct: 18630 VRGRPAPKVTW----RKVGIDN-----VVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTL 18680
Query: 142 KNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPP 193
N AGE V + VL + + + D K C +S PP
Sbjct: 18681 VNPAGEKAVFVNVRVLDTPGPVSDLKV----------SDVTKTSCHVSWAPP 18722
Score = 28.5 bits (62), Expect = 8.1
Identities = 26/125 (20%), Positives = 48/125 (38%), Gaps = 6/125 (4%)
Query: 35 RLQVPTSQVRSRSTSRGDVNDQDAIQ--EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGL 92
RLQ+ + R + R D++A E P+ +++ +D G+ M
Sbjct: 12967 RLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAY 13026
Query: 93 PAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTV 152
P + W+ + + K I + S + D G Y V +N+ G+A +
Sbjct: 13027 PKAEAEWFKENEPLST----KTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFI 13082
Query: 153 QLDVL 157
L V+
Sbjct: 13083 NLKVI 13087
Score = 28.5 bits (62), Expect = 8.1
Identities = 19/73 (26%), Positives = 31/73 (42%), Gaps = 1/73 (1%)
Query: 84 RMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKN 143
+++ V G P P V+W + ++ + I E VR SD+G Y A+N
Sbjct: 21084 KVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVR-SDSGPYPLTARN 21142
Query: 144 RAGEATFTVQLDV 156
GE + + V
Sbjct: 21143 IVGEVGDVITIQV 21155
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 127 bits (320), Expect = 1e-29
Identities = 66/216 (30%), Positives = 115/216 (53%)
Query: 61 EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKG 120
E+ Y P F+ P + EG+ R D KV G P P+ W+ +G+ + +D HK+++ E G
Sbjct: 1406 ERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDG 1465
Query: 121 LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGD 180
SLI SD+G + VA+NRAG ++ +V L V A EH+ PMF+ K ++ + EG
Sbjct: 1466 TQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGS 1525
Query: 181 SVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVS 240
++++ + + P P + W +N++++ + + G L I +D+ WYT +
Sbjct: 1526 RLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTAT 1585
Query: 241 AVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTF 276
A+N+AG T +++V + P K + R T+
Sbjct: 1586 AINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTY 1621
Score = 95.9 bits (237), Expect = 4e-20
Identities = 62/198 (31%), Positives = 92/198 (46%), Gaps = 7/198 (3%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIV--SEKGLH 122
PP F N + G R ++ P P V+WY +G+ ++ D K S+KGL+
Sbjct: 25384 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY 25443
Query: 123 SLIFEVVRASDAGAYACVAKNRAGE----ATFTVQLDVLAKEHKRAPMFIYKPQSKKVLE 178
L V D Y VA+N+ GE A TV L + PMF + + E
Sbjct: 25444 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQE 25503
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G SV E ++S IPPP L W+++ + + + I + + L I+D +D G+Y
Sbjct: 25504 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPN-IEIIHEGLDYYALHIRDTLPEDTGYYR 25562
Query: 239 VSAVNEAGVTTCNTRLDV 256
V+A N AG T+C L V
Sbjct: 25563 VTATNTAGSTSCQAHLQV 25580
Score = 92.8 bits (229), Expect = 3e-19
Identities = 62/213 (29%), Positives = 109/213 (51%), Gaps = 13/213 (6%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVS-EKGLHSL 124
P F Q +++ + EG + +SG P P+VSW+ +G+ + + L + +S G L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
V +++G Y+ A N +G+AT T +L L K P F+ + QS V +G V+L
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAEL--LVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTD-RISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
+ +++ IP P + + R+ +Q + D +IS D +LLI + +D+G Y+V+A N
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGD---LYSLLIAEAYPEDSGTYSVNATN 180
Query: 244 EAGVTTCNTRL------DVTARPNQTLPAPKQL 270
G T L +V A+ +T+ + Q+
Sbjct: 181 SVGRATSTAELLVQGEEEVPAKKTKTIVSTAQI 213
Score = 84.7 bits (208), Expect = 1e-16
Identities = 60/231 (25%), Positives = 94/231 (40%), Gaps = 42/231 (18%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP + +N+++ EG ++ +SG P+P V+WY ++S + I + G+ L
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESS-IDFQITFQSGIARL 954
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDV----------------LAKEHKR----- 163
+ A D+G + C A N AG + + L V E KR
Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014
Query: 164 --------------------APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNE 203
AP FI KP +K++EG SV CQ+ P P ++WK++
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1074
Query: 204 MVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRL 254
+ Y TG L+I DAG YT+ N+ G T+ + L
Sbjct: 1075 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 78.6 bits (192), Expect = 7e-15
Identities = 55/182 (30%), Positives = 94/182 (51%), Gaps = 6/182 (3%)
Query: 75 MSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDA 134
MSI+EG+ R+ K + A DV W LNG + + + ++ VS +L + D
Sbjct: 26743 MSINEGQ--RLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSD-QTLTIKQASHRDE 26799
Query: 135 GAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPP 194
G C++K + G L L+KE AP FI +P+S+ + EG +V C+IS P P
Sbjct: 26800 GILTCISKTKEGIVKCQYDL-TLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSP 26858
Query: 195 KLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRL 254
++ W +NN + +++ +S+ + + +L I++ + D+G YT+ A N G + L
Sbjct: 26859 EIEWFKNNLPISISSN-VSISR-SRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASL 26916
Query: 255 DV 256
V
Sbjct: 26917 MV 26918
Score = 77.8 bits (190), Expect = 1e-14
Identities = 53/197 (26%), Positives = 83/197 (42%), Gaps = 2/197 (1%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKG-LHSL 124
P F + N+++ + KV+G P P V WY G+ + +D L I KG H L
Sbjct: 24623 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24682
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
I V DA Y A N+ G + T L+V P + + L G+ V +
Sbjct: 24683 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSI 24742
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
+ S P P + W++ +++ N + + + V +KDAG+Y V A N
Sbjct: 24743 KIPFSGKPDPVITWQKGQDLID-NNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNR 24801
Query: 245 AGVTTCNTRLDVTARPN 261
G+ LDV P+
Sbjct: 24802 FGIDQKTVELDVADVPD 24818
Score = 69.3 bits (168), Expect = 4e-12
Identities = 53/229 (23%), Positives = 88/229 (38%), Gaps = 22/229 (9%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P FI+ N I G + V G+P P + W+ NG + +K + HSLI
Sbjct: 3649 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDD-HSLI 3707
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK--EHKRA------------------P 165
+ D G Y C+A N G+ + L + +K HK P
Sbjct: 3708 ILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPP 3767
Query: 166 MFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLL 225
F+ + + + +G E + P P + W + N+ + + ++ N G T +
Sbjct: 3768 HFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPN-GSGTFI 3826
Query: 226 IKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRP 274
+ D ++D+G Y A N G +TC L V P + + P
Sbjct: 3827 VNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTP 3875
Score = 65.5 bits (158), Expect = 6e-11
Identities = 60/254 (23%), Positives = 116/254 (45%), Gaps = 21/254 (8%)
Query: 7 GPQNAAAVFQAQDDS--GAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFY 64
G +A + QD+S +++ ++ +SE +V T +++ + G + +D
Sbjct: 4384 GVASAVVSDEKQDESLKPSEEKEESSSESGTEEVATVKIQE---AEGGLIKEDG------ 4434
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P + + +S +EG + ++ A +V+WY + V SD+ K + ++ ++L
Sbjct: 4435 PMIHTPLVDTVS-EEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCL-QDQNTYTL 4490
Query: 125 IFEVVRASD-AGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
+ + V D G Y C A N +G+ + +L V+ + AP+ K + +V G K
Sbjct: 4491 VIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVV---KRAAPVIKRKIEPLEVALGHLAK 4547
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
C+I + P + W + + + +D+ S+ + + +L I D G YT A N
Sbjct: 4548 FTCEIQSAPNVRFQWFKAGREI-YESDKCSI-RSSKYISSLEILRTQVVDCGEYTCKASN 4605
Query: 244 EAGVTTCNTRLDVT 257
E G +C L VT
Sbjct: 4606 EYGSVSCTATLTVT 4619
Score = 64.3 bits (155), Expect = 1e-10
Identities = 39/126 (30%), Positives = 64/126 (50%), Gaps = 1/126 (0%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP F+Q ++M++ +G R+ +V+G+P P V +Y +G +QS L I E L+SL
Sbjct: 103 PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQS-SLDFQISQEGDLYSL 161
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
+ D+G Y+ A N G AT T +L V +E A + ++ E ++
Sbjct: 162 LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRI 221
Query: 185 ECQISA 190
E +I A
Sbjct: 222 EKKIEA 227
Score = 64.3 bits (155), Expect = 1e-10
Identities = 53/209 (25%), Positives = 89/209 (42%), Gaps = 14/209 (6%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP+ +Q + +++ G+ R +SG P P +SWY + + + K + + L
Sbjct: 3192 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3251
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE--HKRAPMFIYKP------QSKKV 176
+ E DA Y C AKN G AT + L V E M +Y P Q
Sbjct: 3252 LIEAF-PEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVT 3310
Query: 177 LEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGW 236
EG + +C++S ++ ++ ++ R++ ++D L I + +D G
Sbjct: 3311 SEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDT---YQLEIAEAYPEDEGT 3367
Query: 237 YTVSAVNEAG--VTTCNTRLDVTARPNQT 263
YT A N G +T N L+V A Q+
Sbjct: 3368 YTFVASNAVGQVSSTANLSLEVQALDRQS 3396
Score = 62.0 bits (149), Expect = 7e-10
Identities = 52/176 (29%), Positives = 78/176 (44%), Gaps = 16/176 (9%)
Query: 96 DVSWYLNGRTV--QSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQ 153
D WY +G + Q + HK +V E+ +H + R SDAG Y V AG +V
Sbjct: 3130 DAHWYKDGIEINFQVQERHKYVV-ERRIHRMFISETRQSDAGEYTFV----AGRNRSSVT 3184
Query: 154 LDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRIS 213
L V A E P + + Q V G + IS P PK+ W + +++ +T
Sbjct: 3185 LYVNAPE---PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKC 3239
Query: 214 LYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV----TARPNQTLP 265
+ + TLL+ + +DA YT A N+ GV T + L V P+Q +P
Sbjct: 3240 KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP 3295
Score = 61.6 bits (148), Expect = 9e-10
Identities = 50/209 (23%), Positives = 84/209 (40%), Gaps = 30/209 (14%)
Query: 97 VSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDV 156
V+WY R +++ + ++ I E G+ L + + D G Y C N GE + +L V
Sbjct: 25295 VTWYFGVRQLENSEKYE-ITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25353
Query: 157 LAKEH-----------------------KRAPMFIYKPQSKKVLEGDSVKLECQISAIPP 193
+R P F +K G++V+ I+ P
Sbjct: 25354 KGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPE 25413
Query: 194 PKLFWKRNNEMVQ-FNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
P + W ++ + ++ + D+ ++ + G L I V D YTV A N+ G +C
Sbjct: 25414 PHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKA 25473
Query: 253 RLDVTARPNQTLPAPKQLRVRPTFSKYLA 281
+L VT P P +RP F + LA
Sbjct: 25474 KLTVTLH-----PPPTDSTLRPMFKRLLA 25497
Score = 60.8 bits (146), Expect = 1e-09
Identities = 47/185 (25%), Positives = 87/185 (47%), Gaps = 8/185 (4%)
Query: 80 GRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYAC 139
G ++ ++ G P PD+ WY G+ + +KM S+ H+L D G Y C
Sbjct: 24242 GEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKM-SSDGRTHTLTVMTEEQEDEGVYTC 24300
Query: 140 VAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWK 199
+A N GE + +L +L + P + K + + G +++L P P + W
Sbjct: 24301 IATNEVGEVETSSKL-LLQATPQFHPGYPLKEKYYGAV-GSTLRLHVMYIGRPVPAMTWF 24358
Query: 200 RNNEMVQFNTDRISLYQDNTGRVT-LLIKDVNKK-DAGWYTVSAVNEAGVTTCNTRLDVT 257
+++Q N++ I++ +NT T L++K+V +K AG Y V N G +++
Sbjct: 24359 HGQKLLQ-NSENITI--ENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQ 24415
Query: 258 ARPNQ 262
+P++
Sbjct: 24416 DKPDK 24420
Score = 60.1 bits (144), Expect = 3e-09
Identities = 36/117 (30%), Positives = 59/117 (50%), Gaps = 2/117 (1%)
Query: 140 VAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWK 199
V R + T T ++ + P + ++ V+EG+SV LEC IS P P + W
Sbjct: 872 VLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWY 931
Query: 200 RNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
R + ++ + D +Q R L+I++ +D+G +T SAVNEAG + + L V
Sbjct: 932 REDYQIESSIDFQITFQSGIAR--LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 59.7 bits (143), Expect = 3e-09
Identities = 62/264 (23%), Positives = 108/264 (40%), Gaps = 44/264 (16%)
Query: 51 GDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD 110
GD+ D++ Q+ F+ + + CR+ G P V W +G+ +++ +
Sbjct: 1646 GDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLT--PIGDPTMVVEWLHDGKPLEAAN 1703
Query: 111 LHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAG----EATFTV-------------- 152
+MI +E G SL + V + D+G C A N+ G AT V
Sbjct: 1704 RLRMI-NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPE 1762
Query: 153 ---------QLDVLAKE-----------HKRAPMFIYKPQSKKVLEGDSVKLECQISAIP 192
+L+ +A E K+ P + P+ +VLEG++ + C+++ P
Sbjct: 1763 GRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYP 1822
Query: 193 PPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
PK+ W N ++++ + R + D G L I D D G V+A N GV
Sbjct: 1823 QPKVNWYLNGQLIR-KSKRFRVRYD--GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKV 1879
Query: 253 RLDVTARPNQTLPAPKQLRVRPTF 276
+L++ R + + RP F
Sbjct: 1880 KLEIQQREDFRSVLRRAPEPRPEF 1903
Score = 58.2 bits (139), Expect = 1e-08
Identities = 46/166 (27%), Positives = 79/166 (47%), Gaps = 13/166 (7%)
Query: 74 NMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASD 133
N+ + E ++ +VS P +V WY + ++ I++E L+ + D
Sbjct: 6166 NIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYE-ILTEGRKRILVIQNAHLED 6223
Query: 134 AGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPP 193
AG Y C + + D K H+ A FI KPQ+ ++LEG+ + C IS
Sbjct: 6224 AGNYNCRLPSS--------RTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSISKESF 6275
Query: 194 PKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTV 239
P + WKR+++ ++ + D+ + D RV L++KD +D G Y V
Sbjct: 6276 P-VQWKRDDKTLE-SGDKYDVIADGKKRV-LVVKDATLQDMGTYVV 6318
Score = 55.5 bits (132), Expect = 6e-08
Identities = 34/125 (27%), Positives = 58/125 (46%), Gaps = 1/125 (0%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P FI P + +I+EG+ ++SG P+P++ W+ N + S + I + ++SL
Sbjct: 26829 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPI-SISSNVSISRSRNVYSLE 26887
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLE 185
SD+G Y AKN G+ + T L VL + + + + L+G
Sbjct: 26888 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQS 26947
Query: 186 CQISA 190
Q+SA
Sbjct: 26948 VQMSA 26952
Score = 54.3 bits (129), Expect = 1e-07
Identities = 35/102 (34%), Positives = 50/102 (49%), Gaps = 3/102 (2%)
Query: 163 RAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV 222
+AP F QS VLEG + E IS P P++ W R+ +++ +T + GR
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 223 TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV---TARPN 261
L I V K ++G Y++ A N +G T L V TA PN
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPN 105
Score = 54.3 bits (129), Expect = 1e-07
Identities = 33/129 (25%), Positives = 63/129 (48%), Gaps = 8/129 (6%)
Query: 141 AKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK----KVLEGDSVKLECQISAIPPPKL 196
A N GE+ ++ L+V+ ++ + P + + KV G+ V + ++ +P PK+
Sbjct: 9066 AVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKI 9125
Query: 197 FWKRNNEMVQFNTDRISLYQDNTGR----VTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
W +N +++ TD + + ++ R L I ++D G YTV+A N G N
Sbjct: 9126 EWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNV 9185
Query: 253 RLDVTARPN 261
++V RP+
Sbjct: 9186 HVEVYDRPS 9194
Score = 53.5 bits (127), Expect = 2e-07
Identities = 38/158 (24%), Positives = 66/158 (41%), Gaps = 4/158 (2%)
Query: 7 GPQNAAAVFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYPP 66
G + +A +D+ + Q LQ + R G + Q++ P
Sbjct: 1738 GTDHTSATLIVKDEKSLVEESQLPEGRKGLQ--RIEELERMAHEGALTGVTTDQKEKQKP 1795
Query: 67 RFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIF 126
+ PE + + EG R +V+G P P V+WYLNG+ ++ + V G+H L
Sbjct: 1796 DIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKS--KRFRVRYDGIHYLDI 1853
Query: 127 EVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRA 164
++ D G A+N G V+L++ +E R+
Sbjct: 1854 VDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRS 1891
Score = 53.1 bits (126), Expect = 3e-07
Identities = 43/153 (28%), Positives = 68/153 (44%), Gaps = 11/153 (7%)
Query: 117 SEKGLHSLIFEVVRASDAGAYACVAK--NRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK 174
+++ + L F V + G Y K N AG + + + + P I +
Sbjct: 9762 NKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFM 9821
Query: 175 KVLEGDSVKLECQISAIPPPKLFWKR-------NNEMVQFNTDRISLYQDNTGRVTLLIK 227
+V EG +V + +I +P P L W + N E V ++T L D+T TL+I
Sbjct: 9822 EVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDT--CTLVIP 9879
Query: 228 DVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARP 260
+ D G YT++AVN G + RL+V RP
Sbjct: 9880 QSRRSDTGLYTITAVNNLGTASKEMRLNVLGRP 9912
Score = 52.8 bits (125), Expect = 4e-07
Identities = 48/162 (29%), Positives = 72/162 (44%), Gaps = 11/162 (6%)
Query: 93 PAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTV 152
P V WY +G V D ++M S++ +H L + SDA Y+CV T T
Sbjct: 2155 PFVKVKWYKDGMEVHEGDKYRMH-SDRKVHFLSILTIDTSDAEDYSCVLVEDENVKT-TA 2212
Query: 153 QLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRI 212
+L V F+ + Q +V E S +LEC +S P + K + V+ ++
Sbjct: 2213 KLIV----EGAVVEFVKELQDIEVPESYSGELECIVS---PENIEGKWYHNDVELKSNGK 2265
Query: 213 SLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRL 254
GR L +KDV K+D G Y S V + TTC ++
Sbjct: 2266 YTITSRRGRQNLTVKDVTKEDQGEY--SFVIDGKKTTCKLKM 2305
Score = 52.8 bits (125), Expect = 4e-07
Identities = 40/147 (27%), Positives = 71/147 (48%), Gaps = 3/147 (2%)
Query: 115 IVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQ-LDVLAKEHKRAPMFIYKPQS 173
IV+E + + + + + + A N G++ V + V+AK+ P +
Sbjct: 17956 IVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNT 18015
Query: 174 KKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD 233
+ G+ +K+E + P P + W ++ E ++ T R+++ + T V L IK+ NK D
Sbjct: 18016 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLK-QTTRVNVEETATSTV-LHIKEGNKDD 18073
Query: 234 AGWYTVSAVNEAGVTTCNTRLDVTARP 260
G YTV+A N AG T N + V +P
Sbjct: 18074 FGKYTVTATNSAGTATENLSVIVLEKP 18100
Score = 52.4 bits (124), Expect = 5e-07
Identities = 32/143 (22%), Positives = 67/143 (46%), Gaps = 2/143 (1%)
Query: 123 SLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSV 182
SL+ ++ + A+N G + V + + P I P+ + G +
Sbjct: 12552 SLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKL 12611
Query: 183 KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAV 242
++E + P P WK+ + V + +++++ ++ + L+IKDV +KD+G+Y+++A
Sbjct: 12612 RIEAHVYGKPHPTCKWKKGEDEV-VTSSHLAVHKADSSSI-LIIKDVTRKDSGYYSLTAE 12669
Query: 243 NEAGVTTCNTRLDVTARPNQTLP 265
N +G T ++ V P P
Sbjct: 12670 NSSGTDTQKIKVVVMDAPGPPQP 12692
Score = 51.6 bits (122), Expect = 9e-07
Identities = 33/153 (21%), Positives = 65/153 (42%), Gaps = 6/153 (3%)
Query: 14 VFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFY------PPR 67
+F +D G N + ++ S+ D + A+ + PP
Sbjct: 3709 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 3768
Query: 68 FIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFE 127
F++ + + +G ++ V G PAP V+W+ + + + + +I + G + I
Sbjct: 3769 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 3828
Query: 128 VVRASDAGAYACVAKNRAGEATFTVQLDVLAKE 160
+ D+G Y C A+N GE+T +L VL ++
Sbjct: 3829 DPQREDSGLYICKAENMLGESTCAAELLVLLED 3861
Score = 51.2 bits (121), Expect = 1e-06
Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKM-IVSEKGLHS 123
PP+ +P ++SIDEG+ + +G P P+V+W GR + S + + I + L +
Sbjct: 27023 PPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTT 27082
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDV 156
LI V+ D G Y N G + TV + +
Sbjct: 27083 LIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27115
Score = 50.4 bits (119), Expect = 2e-06
Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 5/117 (4%)
Query: 52 DVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDL 111
D+++ +A++ F R +N I EG K+SG P P ++WY +G+ ++ +
Sbjct: 1236 DISESEAVESGF-DSRI----KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGER 1290
Query: 112 HKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFI 168
++M + G SL VV D G Y A N G A + +L V AP +I
Sbjct: 1291 YQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYI 1347
Score = 50.1 bits (118), Expect = 3e-06
Identities = 48/189 (25%), Positives = 83/189 (43%), Gaps = 14/189 (7%)
Query: 60 QEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVS---WYLNGRTVQSDDLHKMIV 116
Q K P +F++ +++ + E F L +P + W +G ++ H+ I
Sbjct: 4804 QLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIA 4863
Query: 117 SEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKK- 175
K I +V + SDAG Y CV + E T T +L V + P+ K ++
Sbjct: 4864 DGKDRKLHIIDV-QLSDAGEYTCVLRLGNKEKTSTAKLVV-----EELPVRFVKTLEEEV 4917
Query: 176 -VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDA 234
V++G + L C+++ + W+++ ++V RI R L I D + DA
Sbjct: 4918 TVVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMR-ALTINDADDTDA 4974
Query: 235 GWYTVSAVN 243
G YTV+ N
Sbjct: 4975 GTYTVTVEN 4983
Score = 49.7 bits (117), Expect = 3e-06
Identities = 48/179 (26%), Positives = 73/179 (40%), Gaps = 14/179 (7%)
Query: 68 FIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFE 127
FI P+N+ I EG +S P V W + +T++S D + +I K L+ +
Sbjct: 6249 FISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIADGKK-RVLVVK 6306
Query: 128 VVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQ 187
D G Y + G A L V+ K P+ + +V E V C+
Sbjct: 6307 DATLQDMGTYVVMV----GAARAAAHLTVIEKLRIVVPL-----KDTRVKEQQEVVFNCE 6357
Query: 188 ISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
++ K W RN E + ++ I L +D TL I+D + D Y VS N G
Sbjct: 6358 VNT-EGAKAKWFRNEEAIFDSSKYIILQKDLV--YTLRIRDAHLDDQANYNVSLTNHRG 6413
Score = 49.7 bits (117), Expect = 3e-06
Identities = 34/133 (25%), Positives = 64/133 (48%), Gaps = 10/133 (7%)
Query: 67 RFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIF 126
R + P +M++ EG R G P P V+W G+ + + H++ ++ + F
Sbjct: 26257 RILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK---YKSTF 26313
Query: 127 EV--VRASDAGAYACVAKNRAG----EATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGD 180
E+ V+ASD G Y+ V +N G E T T+Q + ++ +P + P+ +V +
Sbjct: 26314 EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPE-PRVKSPE 26372
Query: 181 SVKLECQISAIPP 193
+VK ++ + P
Sbjct: 26373 AVKSPKRVKSPEP 26385
Score = 49.3 bits (116), Expect = 4e-06
Identities = 45/200 (22%), Positives = 85/200 (42%), Gaps = 17/200 (8%)
Query: 72 PENMSI-DEGR------FCRMDFKVSGLPAPDVSWYLNGRTVQSDD---LHKMIVSEKGL 121
PEN+ I D+G+ + R D+ +P++S+++ R SDD +HK + E
Sbjct: 11799 PENLHIADKGKTFVYLKWRRPDYDGG---SPNLSYHVERRLKGSDDWERVHKGSIKET-- 11853
Query: 122 HSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLE-GD 180
H ++ V + + KN GE+ + +V+ KE + P+ K ++ GD
Sbjct: 11854 HYMVDRCVE-NQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGD 11912
Query: 181 SVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVS 240
+++LE + P P++ W ++ + + + D G Y V+
Sbjct: 11913 TIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVT 11972
Query: 241 AVNEAGVTTCNTRLDVTARP 260
A N AG ++V +P
Sbjct: 11973 ATNTAGSFVAYATVNVLDKP 11992
Score = 48.5 bits (114), Expect = 8e-06
Identities = 50/182 (27%), Positives = 83/182 (45%), Gaps = 21/182 (11%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKG-LHSLIFEVVRA 131
+++++ G D ++S P V WYL G+ ++ D K++ +G +H+L V+
Sbjct: 5898 KDVTVTAGETATFDCELSYEDIP-VEWYLKGKKLEPSD--KVVPRSEGKVHTLTLRDVKL 5954
Query: 132 SDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKP-QSKKVLEGDSVKLECQISA 190
DAG AK+ A V K P+ KP + + V EG + LEC++S
Sbjct: 5955 EDAGEVQLTAKDFKTHANLFV---------KEPPVEFTKPLEDQTVEEGATAVLECEVSR 6005
Query: 191 IPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV-TLLIKDVNKKDAGWYTVSAVNEAGVTT 249
K+ W +N + + + + D GRV L+I D +D YT A + T+
Sbjct: 6006 -ENAKVKWFKNGTEI-LKSKKYEIVAD--GRVRKLVIHDCTPEDIKTYTCDAKDFK--TS 6059
Query: 250 CN 251
CN
Sbjct: 6060 CN 6061
Score = 48.5 bits (114), Expect = 8e-06
Identities = 33/111 (29%), Positives = 55/111 (49%), Gaps = 8/111 (7%)
Query: 51 GDVNDQDAIQEKFYPPRF---IQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTV- 106
G+V D ++++ P V + + + G R+ VSG P P V+W +N RT+
Sbjct: 10202 GEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLP 10261
Query: 107 QSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
Q + +S S++ + + S G Y+ +AKN AGE T+ +DVL
Sbjct: 10262 QEATIETTAISS----SMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVL 10308
Score = 47.4 bits (111), Expect = 2e-05
Identities = 32/114 (28%), Positives = 56/114 (49%), Gaps = 3/114 (2%)
Query: 175 KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDA 234
++LEG V C++S P PK+ W ++ + ++ + +R + GR +L I V +D
Sbjct: 1255 RILEGMGVTFHCKMSGYPLPKIAWYKDGKRIK-HGERYQMDFLQDGRASLRIPVVLPEDE 1313
Query: 235 GWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGLN 288
G YT A N G C+ +L V P L AP + S+ +L+ + ++
Sbjct: 1314 GIYTAFASNIKGNAICSGKLYV--EPAAPLGAPTYIPTLEPVSRIRSLSPRSVS 1365
Score = 47.4 bits (111), Expect = 2e-05
Identities = 47/196 (23%), Positives = 80/196 (40%), Gaps = 7/196 (3%)
Query: 55 DQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKM 114
D+ + P+ + ++ ++ +G +V G P P+ WY NG ++ D
Sbjct: 2021 DKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYW 2080
Query: 115 IVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK 174
E + L+ V A D+ + A N AGE + L V AK+ F + Q
Sbjct: 2081 YWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ---LITFTQELQDV 2137
Query: 175 KVLEGDSV-KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD 233
E D++ EC+ S P K+ W ++ M D+ ++ D L I ++ D
Sbjct: 2138 VAKEKDTMATFECETSE-PFVKVKWYKDG-MEVHEGDKYRMHSDRKVHF-LSILTIDTSD 2194
Query: 234 AGWYTVSAVNEAGVTT 249
A Y+ V + V T
Sbjct: 2195 AEDYSCVLVEDENVKT 2210
Score = 47.4 bits (111), Expect = 2e-05
Identities = 30/82 (36%), Positives = 42/82 (51%), Gaps = 2/82 (2%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G ++ IS P PK+ WK EM TDR+S+ R TL +KD + D+G Y
Sbjct: 22357 GSPFTIDVPISGRPAPKVTWKLE-EMRLKETDRVSI-TTTKDRTTLTVKDSMRGDSGRYF 22414
Query: 239 VSAVNEAGVTTCNTRLDVTARP 260
++ N AGV T + + V RP
Sbjct: 22415 LTLENTAGVKTFSVTVVVIGRP 22436
Score = 46.6 bits (109), Expect = 3e-05
Identities = 42/141 (29%), Positives = 74/141 (52%), Gaps = 14/141 (9%)
Query: 99 WYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLA 158
WY N ++S+ + I S +G +L + V D G Y+ V + + T +++
Sbjct: 2253 WYHNDVELKSNGKYT-ITSRRGRQNLTVKDVTKEDQGEYSFVIDGK--KTTCKLKM---- 2305
Query: 159 KEHKRAPMFIYKPQS-KKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQD 217
K P+ I + S +KV EGD V+LE ++S + + W ++ + VQ +DR+ + D
Sbjct: 2306 ---KPRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQ-PSDRVHIVID 2360
Query: 218 NTGRVTLLIKDVNKKDAGWYT 238
+ LLI+D+ K+DAG Y+
Sbjct: 2361 KQSHM-LLIEDMTKEDAGNYS 2380
Score = 46.6 bits (109), Expect = 3e-05
Identities = 41/178 (23%), Positives = 79/178 (44%), Gaps = 15/178 (8%)
Query: 67 RFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIF 126
+ I+ P++++ E + VS P V W+ ++ D H++ VSE+ +H L+
Sbjct: 2750 KIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRL-VSERKVHKLML 2807
Query: 127 EVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLEC 186
+ + SDAG Y V +A V+ + K K I P++K + EC
Sbjct: 2808 QNISPSDAGEYTAVVGQLECKAKLFVETLHITKTMKN----IEVPETK------TASFEC 2857
Query: 187 QISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
++S P + W +N ++ + + Q + L+I + + +D+ YT N+
Sbjct: 2858 EVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQ--LIIMNTSTEDSAEYTFVCGND 2912
Score = 46.6 bits (109), Expect = 3e-05
Identities = 40/148 (27%), Positives = 68/148 (45%), Gaps = 12/148 (8%)
Query: 41 SQVRSRSTSRGDVN--------DQDAIQEKFYPPRF---IQVPENMSIDEGRFCRMDFKV 89
+Q + R+ +R VN D I + PPR + + +++ G +D V
Sbjct: 12955 AQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATV 13014
Query: 90 SGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEAT 149
G P P VSW +G ++ + KM + ++ L +L V D+G Y A+N +G +
Sbjct: 13015 FGKPMPTVSWKKDGTLLKPAEGIKMAM-QRNLCTLELFSVNRKDSGDYTITAENSSGSKS 13073
Query: 150 FTVQLDVLAKEHKRAPMFIYKPQSKKVL 177
T++L VL K A + I K S + +
Sbjct: 13074 ATIKLKVLDKPGPPASVKINKMYSDRAM 13101
Score = 46.2 bits (108), Expect = 4e-05
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 6/123 (4%)
Query: 141 AKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQISAIPPPKLF 197
A+N GE T + ++ V+A++ AP K E + +L+ I P P +
Sbjct: 13652 AENENGEGTPS-EITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVS 13710
Query: 198 WKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVT 257
WK+ + + +T R+S+ + + TL++ D K DAG YT++ N AG + V
Sbjct: 13711 WKKGEDPLATDT-RVSV-ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVV 13768
Query: 258 ARP 260
+P
Sbjct: 13769 GKP 13771
Score = 45.4 bits (106), Expect = 6e-05
Identities = 49/180 (27%), Positives = 84/180 (46%), Gaps = 25/180 (13%)
Query: 66 PRFIQVPENMS---IDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ-SDDLHKMIVSEKGL 121
PR I + + +S + EG +++ KVS L + + W +G+ VQ SD +H IV +K
Sbjct: 2307 PRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVH--IVIDKQS 2363
Query: 122 HSLIFEVVRASDAGAYA----CVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL 177
H L+ E + DAG Y+ + + +G + +DV+ P+ + V+
Sbjct: 2364 HMLLIEDMTKEDAGNYSFTIPALGLSTSGRVS-VYSVDVIT------PL-----KDVNVI 2411
Query: 178 EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
EG LEC++S + W N+E ++ DR+ T + L+I + D G Y
Sbjct: 2412 EGTKAVLECKVSVPDVTSVKWYLNDEQIK-PDDRVQAIVKGT-KQRLVINRTHASDEGPY 2469
Score = 45.1 bits (105), Expect = 8e-05
Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP + QS+ V +G ++ P P+ W +N ++ +DRI Y
Sbjct: 2031 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIE-RSDRIYWYWPEDNVCE 2089
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 259
L+I+DV +D+ V A+N AG T+ + L V A+
Sbjct: 2090 LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2125
Score = 45.1 bits (105), Expect = 8e-05
Identities = 41/174 (23%), Positives = 71/174 (40%), Gaps = 19/174 (10%)
Query: 79 EGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYA 138
EG + +P P VSW+ +G+ V++ D M H + + VRA DAG Y
Sbjct: 8095 EGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRA-DAGIYT 8153
Query: 139 CVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPP----- 193
+N+ G AT ++ + V+ K + D K C+++ PP
Sbjct: 8154 ITLENKLGSATASINVKVIG----------LPGPCKDIKASDITKSSCKLTWEPPEFDGG 8203
Query: 194 -PKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
P L + T + +N +++ +KD+ ++ V AVN+ G
Sbjct: 8204 TPILHYVLERREAGRRTYIPVMSGEN--KLSWTVKDLIPNGEYFFRVKAVNKVG 8255
Score = 45.1 bits (105), Expect = 8e-05
Identities = 24/86 (27%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Query: 175 KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDA 234
K G SVKL IS P P + W ++++ +Q T+ + ++ T ++LIKD ++ ++
Sbjct: 20578 KYRAGTSVKLRAGISGKPAPTIEWYKDDKELQ--TNALVCVENTTDLASILIKDADRLNS 20635
Query: 235 GWYTVSAVNEAGVTTCNTRLDVTARP 260
G Y + N G + R+ + +P
Sbjct: 20636 GCYELKLRNAMGSASATIRVQILDKP 20661
Score = 44.3 bits (103), Expect = 1e-04
Identities = 52/193 (26%), Positives = 79/193 (40%), Gaps = 18/193 (9%)
Query: 67 RFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIF 126
+F+ E+ ++ EG ++S V W+ N + + +I SE H L
Sbjct: 5270 KFMSPLEDQTVKEGETATFVCELSH-EKMHVVWFKNDAKLHTSRT-VLISSEGKTHKLEM 5327
Query: 127 EVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLEC 186
+ V D K E + T QL VL + P F K K +E D + L+C
Sbjct: 5328 KEVTLDDISQIKAQVK----ELSSTAQLKVLEAD----PYFTVKLHDKTAVEKDEITLKC 5379
Query: 187 QISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
++S P K F K E+V + + S+ D R+ L IK + KD G Y V + G
Sbjct: 5380 EVSKDVPVKWF-KDGEEIVP--SPKYSIKADGLRRI-LKIKKADLKDKGEY----VCDCG 5431
Query: 247 VTTCNTRLDVTAR 259
+ V AR
Sbjct: 5432 TDKTKANVTVEAR 5444
Score = 44.3 bits (103), Expect = 1e-04
Identities = 27/101 (26%), Positives = 43/101 (42%), Gaps = 4/101 (3%)
Query: 60 QEKFYPPRF---IQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIV 116
QEK PP +++ E + + G R + G+P P W +G +++D+ H +
Sbjct: 11197 QEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDE-HYTVE 11255
Query: 117 SEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
++ L + D G Y N AG T V L VL
Sbjct: 11256 TDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVL 11296
Score = 44.3 bits (103), Expect = 1e-04
Identities = 36/144 (25%), Positives = 67/144 (46%), Gaps = 4/144 (2%)
Query: 119 KGLHSLIFEVVRASDAGAYACVAKNRAGEAT-FTVQLDVLAKEHKRAPMFIYKPQSKKVL 177
K L ++I + + + + VA N G + ++ + ++AK+ P S V
Sbjct: 16879 KSLQAVITNLTQGEEY-LFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQ 16937
Query: 178 EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
G +K+E IS P P + W ++ ++ T RI++ D+ TL IK+ +K D G Y
Sbjct: 16938 VGQDLKIEVPISGRPKPTITWTKDGLPLK-QTTRINV-TDSLDLTTLSIKETHKDDGGQY 16995
Query: 238 TVSAVNEAGVTTCNTRLDVTARPN 261
++ N G T + + +P+
Sbjct: 16996 GITVANVVGQKTASIEIVTLDKPD 17019
Score = 43.9 bits (102), Expect = 2e-04
Identities = 27/106 (25%), Positives = 53/106 (50%), Gaps = 2/106 (1%)
Query: 155 DVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISL 214
+V+AK+ P + V+EG+ + + A+P P + W ++ + V+ +DR+++
Sbjct: 8072 NVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVK-ASDRLTM 8130
Query: 215 YQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARP 260
D+ + K V + DAG YT++ N+ G T + + V P
Sbjct: 8131 KNDHISAHLEVPKSV-RADAGIYTITLENKLGSATASINVKVIGLP 8175
Score = 43.9 bits (102), Expect = 2e-04
Identities = 44/180 (24%), Positives = 77/180 (42%), Gaps = 19/180 (10%)
Query: 137 YACVAKNRAGEATFTVQLD----VLAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQIS 189
+ +A+N AG F+ D + A++ AP P+ K V+ G++ LE I
Sbjct: 18370 FRVIARNAAGN--FSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIR 18427
Query: 190 AIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTT 249
P P + W ++ + ++ R+ + + + TL++KD + D G Y + N G +
Sbjct: 18428 GKPIPDVVWSKDGKELEETAARMEI-KSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKS 18486
Query: 250 CNTRLDVTARPNQTLPAPKQLRVRPTFSK--YLA----LNGKGLNVKQAFNPEGEFQRLA 303
+ V RP P L+V ++ YLA L G N+ + E RL+
Sbjct: 18487 IPITVKVLDRPG---PPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS 18543
Score = 43.1 bits (100), Expect = 3e-04
Identities = 51/200 (25%), Positives = 85/200 (42%), Gaps = 25/200 (12%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P F++ E+ ++ E ++S A +V WY NGR ++ +K + +H L
Sbjct: 6517 PTEFVEHLEDQTVTEFDDAVFSCQLSREKA-NVKWYRNGREIKEGKKYKF-EKDGSIHRL 6574
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL---EGDS 181
I + R D YAC ++R A V + + E R P I + V+ E +
Sbjct: 6575 IIKDCRLDDECEYACGVEDRKSRARLFV--EEIPVEIIRPPQDILEAPGADVVFLAELNK 6632
Query: 182 VKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV-TLLIKDVNKKDAGWYTVS 240
K+E Q W RNN MV D+ + + G++ L I D+ +D G Y
Sbjct: 6633 DKVEVQ----------WLRNN-MVVVQGDKHQMMSE--GKIHRLQICDIKPRDQGEYRFI 6679
Query: 241 AVNEAGVTTCNTRLDVTARP 260
A ++ +L++ A P
Sbjct: 6680 AKDK----EARAKLELAAAP 6695
Score = 43.1 bits (100), Expect = 3e-04
Identities = 32/135 (23%), Positives = 64/135 (47%), Gaps = 6/135 (4%)
Query: 115 IVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK 174
I + KGL ++ + + + +A N AG + V+ KE P + +
Sbjct: 14709 ITTVKGLECVVRNLTEGEEY-TFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQ 14767
Query: 175 KVL---EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNK 231
K++ GD++K+E + P P + WK+ +++++ T R++ T + L I + +
Sbjct: 14768 KLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILK-QTQRVNFETTATSTI-LNINECVR 14825
Query: 232 KDAGWYTVSAVNEAG 246
D+G Y ++A N G
Sbjct: 14826 SDSGPYPLTARNIVG 14840
Score = 42.4 bits (98), Expect = 5e-04
Identities = 29/102 (28%), Positives = 50/102 (49%), Gaps = 10/102 (9%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYL-------NGRTVQSD-DLHKMIVS 117
P I + E M ++EG + K+ G+P P ++W+ N V D ++K++V
Sbjct: 9812 PPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD 9871
Query: 118 EKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
+ +L+ R SD G Y A N G A+ ++L+VL +
Sbjct: 9872 D--TCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGR 9911
Score = 42.0 bits (97), Expect = 7e-04
Identities = 34/128 (26%), Positives = 56/128 (43%), Gaps = 8/128 (6%)
Query: 141 AKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK---KVLEGDSVKLECQISAIPPPKLF 197
A N AGE V E + P K +++ G ++++ ++ P P
Sbjct: 8773 AVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKV 8832
Query: 198 WKRNNEMVQFNTDRISLYQDNTG-RVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
W + E + + DR+ + DN G + L+IKD +KD G Y ++A N G R++V
Sbjct: 8833 WTK--EEGELDKDRVVI--DNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 8888
Query: 257 TARPNQTL 264
P L
Sbjct: 8889 FDVPGPVL 8896
Score = 42.0 bits (97), Expect = 7e-04
Identities = 52/193 (26%), Positives = 78/193 (40%), Gaps = 23/193 (11%)
Query: 93 PAPDVSWYLNGRTVQSDDLHK---MIVSEKGLHSLIFEVVRASDAGAYA--CVAKNRAG- 146
P D L G V+ DL M + + F V + G Y AKN AG
Sbjct: 13992 PKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGA 14051
Query: 147 -----EATFTVQLDVLAKEHKRAPMFIYKPQSKKVLE---GDSVKLEC-QISAIPPPKLF 197
E+T T+ + K+ AP + P K L GD++ L I P PK
Sbjct: 14052 ISAPSESTETI----ICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSS 14107
Query: 198 WKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVT 257
W + + ++ +D + T + L IK +KDAG YT++A N G + ++ V
Sbjct: 14108 WSKAGKDIR-PSDITQITSTPTSSM-LTIKYATRKDAGEYTITATNPFGTKVEHVKVTVL 14165
Query: 258 ARPNQTLPAPKQL 270
P P P ++
Sbjct: 14166 DVPGP--PGPVEI 14176
Score = 42.0 bits (97), Expect = 7e-04
Identities = 28/99 (28%), Positives = 46/99 (46%), Gaps = 2/99 (2%)
Query: 59 IQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSE 118
+ K + P+ ++ + G + SG P P ++W G+ + ++ H ++
Sbjct: 24716 VPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQ-KGQDLIDNNGHYQVIVT 24774
Query: 119 KGLHSLIF-EVVRASDAGAYACVAKNRAGEATFTVQLDV 156
+ SL+F V DAG Y AKNR G TV+LDV
Sbjct: 24775 RSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 24813
Score = 41.2 bits (95), Expect = 0.001
Identities = 28/108 (25%), Positives = 48/108 (44%), Gaps = 2/108 (1%)
Query: 60 QEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEK 119
+E+ PP+ + +PE ++I G+ R++ V G P P W G H +
Sbjct: 12589 KEQLLPPKIL-MPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKAD 12646
Query: 120 GLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMF 167
LI + V D+G Y+ A+N +G T +++ V+ P F
Sbjct: 12647 SSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 12694
Score = 41.2 bits (95), Expect = 0.001
Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 6/102 (5%)
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V G +V L+ + P P + WK++ +++ Q N TL + VN+KD+G
Sbjct: 13002 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNL--CTLELFSVNRKDSG 13059
Query: 236 WYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFS 277
YT++A N +G + +L V +P P +++ +S
Sbjct: 13060 DYTITAENSSGSKSATIKLKVLDKPG----PPASVKINKMYS 13097
Score = 41.2 bits (95), Expect = 0.001
Identities = 39/150 (26%), Positives = 63/150 (42%), Gaps = 17/150 (11%)
Query: 47 STSRGDVNDQDAIQEKFYPPRFIQVP---ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNG 103
S S G + +D + PPR P + + + G ++D + G P P + W + G
Sbjct: 16221 SESTGAITARDEVD----PPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQW-IKG 16275
Query: 104 RTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKR 163
S+ I S SL + D+G Y AKN AGE + TV + VL +
Sbjct: 16276 DQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPG-- 16333
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPP 193
P+ V+ G + + +C ++ PP
Sbjct: 16334 ------PPEGPVVISGVTAE-KCTLAWKPP 16356
Score = 41.2 bits (95), Expect = 0.001
Identities = 21/86 (24%), Positives = 36/86 (41%)
Query: 171 PQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVN 230
P + EG + + C + P P++ W + ++ TL+I DV
Sbjct: 27030 PSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQ 27089
Query: 231 KKDAGWYTVSAVNEAGVTTCNTRLDV 256
K+D G YT+S NE G + + +
Sbjct: 27090 KQDGGLYTLSLGNEFGSDSATVNIHI 27115
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/204 (20%), Positives = 72/204 (35%), Gaps = 37/204 (18%)
Query: 90 SGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAG--- 146
S L A +V+WY +G+ ++ + + S G + L + SD G Y C G
Sbjct: 26437 SVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSK 26496
Query: 147 -------------------------------EATFTVQLDVLAKEH-KRAPMFIYKPQSK 174
E+T T + + A E P+ + Q
Sbjct: 26497 TNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDT 26556
Query: 175 KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDA 234
V K + + P P W ++ + + + L +D G L I + D+
Sbjct: 26557 TVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT-QGGKYKLSEDK-GGFFLEIHKTDTSDS 26614
Query: 235 GWYTVSAVNEAGVTTCNTRLDVTA 258
G YT + N AG + + +L + A
Sbjct: 26615 GLYTCTVKNSAGSVSSSCKLTIKA 26638
Score = 40.4 bits (93), Expect = 0.002
Identities = 30/129 (23%), Positives = 60/129 (46%), Gaps = 7/129 (5%)
Query: 137 YACVAKNRAGEATFTVQLD--VLAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQISAI 191
+ +AKN AG + + + ++ AP + K + G++ +LE +S
Sbjct: 15124 FRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGR 15183
Query: 192 PPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCN 251
PPP + W ++ + ++ T ++ + + L+ KD ++D+G YT++A N G
Sbjct: 15184 PPPTMEWSKDGKELE-GTAKLEIKIADFS-TNLVNKDSTRRDSGAYTLTATNPGGFAKHI 15241
Query: 252 TRLDVTARP 260
+ V RP
Sbjct: 15242 FNVKVLDRP 15250
Score = 40.4 bits (93), Expect = 0.002
Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Query: 152 VQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDR 211
+ + V+AK+ P F + VL G+ +K++ P P + W ++N ++ T R
Sbjct: 15830 LSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLK-QTTR 15888
Query: 212 ISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
++ + L IKD ++D G Y V N AG
Sbjct: 15889 VNA-ESTENNSLLTIKDACREDVGHYVVKLTNSAG 15922
Score = 40.4 bits (93), Expect = 0.002
Identities = 21/86 (24%), Positives = 38/86 (44%), Gaps = 1/86 (1%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 132
++ ++ + K +G P P W +G+ + +K+ +KG L S
Sbjct: 26554 QDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS-EDKGGFFLEIHKTDTS 26612
Query: 133 DAGAYACVAKNRAGEATFTVQLDVLA 158
D+G Y C KN AG + + +L + A
Sbjct: 26613 DSGLYTCTVKNSAGSVSSSCKLTIKA 26638
Score = 40.0 bits (92), Expect = 0.003
Identities = 39/163 (23%), Positives = 66/163 (40%), Gaps = 16/163 (9%)
Query: 97 VSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDV 156
V W+ N + + + M E HS+ F+ + D A + EA TV
Sbjct: 5654 VKWFKNDQRLHTTRSVSM-QDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVL--- 5709
Query: 157 LAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQ 216
+ P F K Q +E D V L+C+IS P ++K E+ + ++ +
Sbjct: 5710 -----EGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEI---KPSKNAVIK 5761
Query: 217 DNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 259
+ + L++K K D G YT + G + +LD+ R
Sbjct: 5762 ADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDIEDR 5800
Score = 40.0 bits (92), Expect = 0.003
Identities = 32/142 (22%), Positives = 62/142 (43%), Gaps = 14/142 (9%)
Query: 122 HSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL---E 178
H F V+ + AG ++ +++ + A++ P P+ K +
Sbjct: 16202 HRYEFRVIARNAAGVFSEPSESTGA---------ITARDEVDPPRISMDPKYKDTIVVHA 16252
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G+S K++ I P P + W + ++ + NT R+ + + +L +KD + D+G Y
Sbjct: 16253 GESFKVDADIYGKPIPTIQWIKGDQELS-NTARLEIKSTDFA-TSLSVKDAVRVDSGNYI 16310
Query: 239 VSAVNEAGVTTCNTRLDVTARP 260
+ A N AG + + V RP
Sbjct: 16311 LKAKNVAGERSVTVNVKVLDRP 16332
Score = 40.0 bits (92), Expect = 0.003
Identities = 30/129 (23%), Positives = 58/129 (44%), Gaps = 7/129 (5%)
Query: 137 YACVAKNRAGEATFTVQLD--VLAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQISAI 191
+ +AKN AG + + AK+ P P+ + + G++ +LE +
Sbjct: 17288 FRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGK 17347
Query: 192 PPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCN 251
P P + W R ++ ++ + R + ++ + L++KD + D G Y + A N AG +
Sbjct: 17348 PLPTIEWLRGDKEIE-ESARCEI-KNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFP 17405
Query: 252 TRLDVTARP 260
+ V RP
Sbjct: 17406 VNVKVLDRP 17414
Score = 40.0 bits (92), Expect = 0.003
Identities = 24/98 (24%), Positives = 41/98 (41%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F ++ N EG+ + +VSG+P P + W +G+ + ++I ++L
Sbjct: 25490 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25549
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKR 163
D G Y A N AG + L V +K+
Sbjct: 25550 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25587
Score = 39.7 bits (91), Expect = 0.004
Identities = 40/158 (25%), Positives = 61/158 (38%), Gaps = 13/158 (8%)
Query: 93 PAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTV 152
P V W + + +Q D K I EK +H L+ R SDAG Y VA A V
Sbjct: 3038 PDITVQWMKDDQELQITDRIK-IQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFV 3096
Query: 153 Q-LDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDR 211
+ DV + K+ I K ++ E + ++ W ++ + F
Sbjct: 3097 EGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAH----------WYKDGIEINFQVQE 3146
Query: 212 ISLYQDNTGRVTLLIKDVNKKDAGWYT-VSAVNEAGVT 248
Y + I + + DAG YT V+ N + VT
Sbjct: 3147 RHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVT 3184
Score = 39.7 bits (91), Expect = 0.004
Identities = 35/129 (27%), Positives = 56/129 (43%), Gaps = 5/129 (3%)
Query: 64 YPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS 123
YPP I ++ EG+ R +VSG VSWY + ++ +M E
Sbjct: 3297 YPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQL 3355
Query: 124 LIFEVVRASDAGAYACVAKNRAGE--ATFTVQLDVLAKEHKRAPMFIYK-PQSKKVLEGD 180
I E D G Y VA N G+ +T + L+V A + + + + + +S+ V +
Sbjct: 3356 EIAEAY-PEDEGTYTFVASNAVGQVSSTANLSLEVQALDRQSSGKDVRESAKSQAVADSS 3414
Query: 181 SVKLECQIS 189
K E +IS
Sbjct: 3415 FTKEESKIS 3423
Score = 39.7 bits (91), Expect = 0.004
Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 2/82 (2%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G ++++ ++ P P + W + +++ R+ L QD RV L IK+ + D G Y
Sbjct: 11618 GQTIRILARVKGRPEPDITWTKEGKVL-VREKRVDLIQD-LPRVELQIKEAVRADHGKYI 11675
Query: 239 VSAVNEAGVTTCNTRLDVTARP 260
+SA N +G + ++V RP
Sbjct: 11676 ISAKNSSGHAQGSAIVNVLDRP 11697
Score = 39.7 bits (91), Expect = 0.004
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 1/76 (1%)
Query: 84 RMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKN 143
R+ + G PAP VSW G + D + S +LI + SDAG Y KN
Sbjct: 13696 RLKIPIKGKPAPSVSWK-KGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKN 13754
Query: 144 RAGEATFTVQLDVLAK 159
AG T+ + V+ K
Sbjct: 13755 VAGTKEGTISIKVVGK 13770
Score = 39.7 bits (91), Expect = 0.004
Identities = 21/91 (23%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 69 IQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEV 128
++ E + G ++ +SG PAP + WY + + +Q++ L + + L S++ +
Sbjct: 20571 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNAL-VCVENTTDLASILIKD 20629
Query: 129 VRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
++G Y +N G A+ T+++ +L K
Sbjct: 20630 ADRLNSGCYELKLRNAMGSASATIRVQILDK 20660
Score = 39.7 bits (91), Expect = 0.004
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKD-VNKKDAGWY 237
G S++L +S PPP + W + + + I D T +LLI D VN+ DAG Y
Sbjct: 23156 GASLRLMVSVSGRPPPVITWSKQG--IDLASRAII---DTTESYSLLIVDKVNRYDAGKY 23210
Query: 238 TVSAVNEAGVTTCNTRLDVTARP 260
T+ A N++G + + V P
Sbjct: 23211 TIEAENQSGKKSATVLVKVYDTP 23233
Score = 39.3 bits (90), Expect = 0.005
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 2/85 (2%)
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V G ++L ++ P PK+ W + +M+ RI++ ++ + T+ I D + D G
Sbjct: 7397 VKAGTKIELPATVTGKPEPKITWTKA-DMILKQDKRITI-ENVPKKSTVTIVDSKRSDTG 7454
Query: 236 WYTVSAVNEAGVTTCNTRLDVTARP 260
Y + AVN G T ++V +P
Sbjct: 7455 TYIIEAVNVCGRATAVVEVNVLDKP 7479
Score = 39.3 bits (90), Expect = 0.005
Identities = 36/140 (25%), Positives = 63/140 (45%), Gaps = 12/140 (8%)
Query: 137 YACVAKNRAGEATFT-VQLDVLAKEHKRAPMFIYKP---QSKKVLEGDSVKLECQISAIP 192
+ +A N AGE+ V VL K+ P I + + + GD+++L I +P
Sbjct: 10882 FRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVP 10941
Query: 193 PPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
PK+ WK+ + RI + + L I++ +D G Y+++ N AG T +
Sbjct: 10942 FPKVTWKKEDRDAPTKA-RIDVTPVGS---KLEIRNAAHEDGGIYSLTVENPAGSKTVSV 10997
Query: 253 RLDVTARPNQTLPAPKQLRV 272
++ V +P P+ L V
Sbjct: 10998 KVLVLDKPG----PPRDLEV 11013
Score = 39.3 bits (90), Expect = 0.005
Identities = 37/128 (28%), Positives = 62/128 (48%), Gaps = 14/128 (10%)
Query: 141 AKNRAGEAT-FTVQLDVLAKEHKRAP---MFIYKPQSKKVLEGDSVKLECQISAIPPPKL 196
A+N+AG + + L VL KE P M + + V G ++K++ IS P PK+
Sbjct: 20144 AENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKV 20203
Query: 197 FWKRNN----EMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
R+ ++FNT+ + +N +T+ +K+ DAG Y ++A N +G T
Sbjct: 20204 TLSRDGVPLKATMRFNTE---ITAEN---LTINLKESVTADAGRYEITAANSSGTTKAFI 20257
Query: 253 RLDVTARP 260
+ V RP
Sbjct: 20258 NIVVLDRP 20265
Score = 38.9 bits (89), Expect = 0.006
Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Query: 75 MSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDA 134
+++ G+ R+ +V G P PD++W G+ + + +I + I E VRA D
Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA-DH 11671
Query: 135 GAYACVAKNRAGEATFTVQLDVL 157
G Y AKN +G A + ++VL
Sbjct: 11672 GKYIISAKNSSGHAQGSAIVNVL 11694
Score = 38.9 bits (89), Expect = 0.006
Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
Query: 85 MDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNR 144
+D +SG PAP V+W L ++ D I + K +L + D+G Y +N
Sbjct: 22362 IDVPISGRPAPKVTWKLEEMRLKETD-RVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 22420
Query: 145 AGEATFTVQLDVLAK 159
AG TF+V + V+ +
Sbjct: 22421 AGVKTFSVTVVVIGR 22435
Score = 38.5 bits (88), Expect = 0.008
Identities = 42/153 (27%), Positives = 60/153 (39%), Gaps = 16/153 (10%)
Query: 92 LPAPDV--SWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEAT 149
L PDV W L G+ + + ++I K H LI + G + A N A
Sbjct: 5469 LSEPDVHGQWKLKGQPLTASPDCEIIEDGKK-HILILHNCQLGMTGEVSFQAANAKSAAN 5527
Query: 150 FTVQLDVLAKEHKRAPMFIYKPQSK-KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFN 208
V K P+ P S KV E D K EC++S P + K E+
Sbjct: 5528 LKV---------KELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEIT--G 5576
Query: 209 TDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSA 241
DR L +D T + +++IK +D Y A
Sbjct: 5577 DDRFELIKDGT-KHSMVIKSAAFEDEAKYMFEA 5608
Score = 38.5 bits (88), Expect = 0.008
Identities = 26/138 (18%), Positives = 62/138 (44%), Gaps = 9/138 (6%)
Query: 133 DAGAYACVAKNRAGEATFTVQLD--VLAKEHKRAPMFIYKPQ---SKKVLEGDSVKLECQ 187
D + +A+N G + Q ++ ++ P+ + P+ + G+S++++
Sbjct: 21617 DRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKAL 21676
Query: 188 ISAIPPPKLFWKRNNEMVQFNTDRISL-YQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
+ P P++ W ++ ++ R+++ D G +L ++D + G YTV A N +G
Sbjct: 21677 VQGRPVPRVTWFKDGVEIE---KRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASG 21733
Query: 247 VTTCNTRLDVTARPNQTL 264
++ V P + +
Sbjct: 21734 SAKAEIKVKVQDTPGKVV 21751
Score = 38.5 bits (88), Expect = 0.008
Identities = 21/82 (25%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G + L+ + P PK+ W + ++ + +++SL Q R T +IK ++ D+G YT
Sbjct: 22757 GSDLVLDAAVGGKPEPKIIWTKGDKELDL-CEKVSL-QYTGKRATAVIKFCDRSDSGKYT 22814
Query: 239 VSAVNEAGVTTCNTRLDVTARP 260
++ N +G + + V P
Sbjct: 22815 LTVKNASGTKAVSVMVKVLDSP 22836
Score = 38.5 bits (88), Expect = 0.008
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 132
+ ++I G R+ VSG P P ++W G + S +I + + LI + V
Sbjct: 23149 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLAS---RAIIDTTESYSLLIVDKVNRY 23205
Query: 133 DAGAYACVAKNRAGEATFTVQLDV 156
DAG Y A+N++G+ + TV + V
Sbjct: 23206 DAGKYTIEAENQSGKKSATVLVKV 23229
Score = 38.1 bits (87), Expect = 0.010
Identities = 29/115 (25%), Positives = 42/115 (36%), Gaps = 12/115 (10%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
A + KP+S V EG+S + C P P + W R +++ +T + T
Sbjct: 26255 AARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVL--STSARHQVTTTKYKST 26312
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCN----------TRLDVTARPNQTLPAPK 268
I V D G Y+V N G T VT+ P P P+
Sbjct: 26313 FEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPR 26367
Score = 37.7 bits (86), Expect = 0.013
Identities = 24/69 (34%), Positives = 37/69 (53%), Gaps = 4/69 (5%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLL-IKDVNKKDAGWY 237
G +++L + PPPK+ W + N ++ DRI L +T T L ++VNK DAG Y
Sbjct: 13403 GVTMRLYVPVKGRPPPKITWSKPNVNLR---DRIGLDIKSTDFDTFLRCENVNKYDAGKY 13459
Query: 238 TVSAVNEAG 246
++ N G
Sbjct: 13460 ILTLENSCG 13468
Score = 37.7 bits (86), Expect = 0.013
Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 11/92 (11%)
Query: 157 LAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTD-RI 212
+AKE + P+F + +K L G S + P P + W + + TD R
Sbjct: 19871 IAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPD------TDLRT 19924
Query: 213 SLYQDNT-GRVTLLIKDVNKKDAGWYTVSAVN 243
Y D T R +L I++ N+ D+G YT++ N
Sbjct: 19925 RAYVDTTDSRTSLTIENANRNDSGKYTLTIQN 19956
Score = 37.4 bits (85), Expect = 0.017
Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 3/99 (3%)
Query: 64 YPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ-SDDLHKMIVSEKGLH 122
+ PR + + G+ R V P +V WY NG +Q S +H + G+
Sbjct: 26067 HAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIH--YTNTSGVL 26124
Query: 123 SLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEH 161
+L D+G Y V N GEA+ LDV ++
Sbjct: 26125 TLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDY 26163
Score = 37.0 bits (84), Expect = 0.023
Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
Query: 69 IQVPENM-SIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI-F 126
+++P N SI G +++ V G P P++SW +G ++ ++ V E +++
Sbjct: 18009 LKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTT--RVNVEETATSTVLHI 18066
Query: 127 EVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
+ D G Y A N AG AT + + VL K
Sbjct: 18067 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 18099
Score = 37.0 bits (84), Expect = 0.023
Identities = 28/120 (23%), Positives = 54/120 (45%), Gaps = 8/120 (6%)
Query: 43 VRSRSTSRGDVNDQDAIQEKFYPPRF---IQVPENMSIDEGRFCRMDFKVSGLPAPDVSW 99
V S S G + +D ++ PPR ++ + + + G +++ ++G P P +SW
Sbjct: 19463 VSEPSESTGPIIVKDDVE----PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISW 19518
Query: 100 YLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
+G ++ ++I ++ + + +R D G Y KN AG + V VL K
Sbjct: 19519 AKDGIEIEERARTEIISTDNHTLLTVKDCIR-RDTGQYVLTLKNVAGTRSVAVNCKVLDK 19577
Score = 36.6 bits (83), Expect = 0.030
Identities = 38/139 (27%), Positives = 63/139 (45%), Gaps = 15/139 (10%)
Query: 141 AKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQISAIPPPKLF 197
A N AG V DV E + AP F + ++ L G S+++ I P P++
Sbjct: 14445 AINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVT 14504
Query: 198 WKRNNEMVQFNTDRISLYQDNTGRVTLL-IKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
W ++N ++ +R ++ +NT TLL I + N+ D G + ++ N AG + + V
Sbjct: 14505 WTKDNINLK---NRANI--ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRV 14559
Query: 257 TARPNQTLPAPKQLRVRPT 275
P L +RPT
Sbjct: 14560 LDTPGPV------LNLRPT 14572
Score = 36.6 bits (83), Expect = 0.030
Identities = 30/132 (22%), Positives = 55/132 (41%), Gaps = 5/132 (3%)
Query: 163 RAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV 222
+AP F + ++ V + L C+++ P P + W R + + + + + + G
Sbjct: 24621 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 24680
Query: 223 TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLAL 282
L+I V DA Y V A N+ G + L+V LP + AL
Sbjct: 24681 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLP-----KTLEGMGAVHAL 24735
Query: 283 NGKGLNVKQAFN 294
G+ +++K F+
Sbjct: 24736 RGEVVSIKIPFS 24747
Score = 35.8 bits (81), Expect = 0.051
Identities = 30/120 (25%), Positives = 56/120 (46%), Gaps = 12/120 (10%)
Query: 47 STSRGDVNDQDAIQEKFYPPRFIQV--PENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGR 104
S + G++ D IQE+ P FI + + + G R+ + G P P SW +G+
Sbjct: 9488 SDTTGEIPATD-IQEE--PEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGK 9544
Query: 105 TVQS--DDLHKM-----IVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
++ D +H + + + + +I + S G Y+ AKN+AG+ T ++ V+
Sbjct: 9545 AKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVM 9604
Score = 35.8 bits (81), Expect = 0.051
Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 5/95 (5%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P + + ++I G + + SG P P VSW+ + V DD + + +L
Sbjct: 10513 PTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPA---TL 10569
Query: 125 IFEVVRA--SDAGAYACVAKNRAGEATFTVQLDVL 157
E ++A SD+G Y V +N G Q++V+
Sbjct: 10570 ALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVV 10604
Score = 35.8 bits (81), Expect = 0.051
Identities = 22/84 (26%), Positives = 36/84 (42%), Gaps = 1/84 (1%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 132
+ + I G R+ V G P P V+W+ +G ++ ++ I G SL
Sbjct: 21661 DGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEK-RMNMEITDVLGSTSLFVRDATRD 21719
Query: 133 DAGAYACVAKNRAGEATFTVQLDV 156
G Y AKN +G A +++ V
Sbjct: 21720 HRGVYTVEAKNASGSAKAEIKVKV 21743
Score = 35.4 bits (80), Expect = 0.066
Identities = 24/100 (24%), Positives = 44/100 (44%), Gaps = 10/100 (10%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT------LLIKDVNKK 232
G +++ I P PK W+ + + + D + ++ T ++I + +
Sbjct: 9520 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9579
Query: 233 DAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRV 272
G Y+++A N+AG T N R+ V P PK L+V
Sbjct: 9580 HTGKYSITAKNKAGQKTANCRVKVMDVPG----PPKDLKV 9615
Score = 35.4 bits (80), Expect = 0.066
Identities = 42/166 (25%), Positives = 70/166 (42%), Gaps = 16/166 (9%)
Query: 114 MIVSEKGLHSLIFEVVRASDAGAY--ACVAKNRAGEATFT-VQLDVLAKEHKRAPMFIYK 170
M G++ EV + + Y A N+AG V ++ +E AP
Sbjct: 16581 MCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLD 16640
Query: 171 PQSKKVLE---GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIK 227
+ +K++ G S++L I P P++ W + + + R + D T T L+
Sbjct: 16641 LELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEI-----RDAAIIDVTSSFTSLVL 16695
Query: 228 D-VNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRV 272
D VN+ D+G YT++ N +G + VT R T P L+V
Sbjct: 16696 DNVNRYDSGKYTLTLENSSGTKSA----FVTVRVLDTPSPPVNLKV 16737
Score = 35.4 bits (80), Expect = 0.066
Identities = 25/110 (22%), Positives = 50/110 (45%), Gaps = 2/110 (1%)
Query: 156 VLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLY 215
V+A++ + P + V + +K++ P + W+++ + ++ T R+++
Sbjct: 19081 VIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLK-ETTRVNVS 19139
Query: 216 QDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLP 265
T +L IK+ +K+D G Y + N AG T + V RP P
Sbjct: 19140 SSKTV-TSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGP 19188
Score = 35.4 bits (80), Expect = 0.066
Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 1/85 (1%)
Query: 84 RMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKN 143
++D G P V+W +G+T++ + + S K + SL + D G Y N
Sbjct: 19108 KIDVPFKGRPQATVNWRKDGQTLK-ETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSN 19166
Query: 144 RAGEATFTVQLDVLAKEHKRAPMFI 168
AG T + + VL + P+ I
Sbjct: 19167 SAGSITVPITIIVLDRPGPPGPIRI 19191
Score = 35.4 bits (80), Expect = 0.066
Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP + +S +V G + + + + P ++ W N +Q + +I Y + +G +T
Sbjct: 26068 APRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQ-ESSKIH-YTNTSGVLT 26125
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVT 257
L I D + D+G Y N G + LDVT
Sbjct: 26126 LEILDCHTDDSGTYRAVCTNYKGEASDYATLDVT 26159
Score = 35.0 bits (79), Expect = 0.086
Identities = 26/114 (22%), Positives = 50/114 (43%), Gaps = 8/114 (7%)
Query: 47 STSRGDVNDQDAIQEKFYPPRFIQVP---ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNG 103
S S G + +D ++ PR P + + ++ G R++ V G P P + W
Sbjct: 17303 SDSTGPITAKDEVEL----PRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGD 17358
Query: 104 RTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
+ ++ ++ ++ ++ + +R D G Y A N AG +F V + VL
Sbjct: 17359 KEIEESARCEIKNTDFKALLIVKDAIRI-DGGQYILRASNVAGSKSFPVNVKVL 17411
Score = 34.7 bits (78), Expect = 0.11
Identities = 22/104 (21%), Positives = 44/104 (42%), Gaps = 5/104 (4%)
Query: 56 QDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMI 115
+D + E P F + S+ G+ +++ +SG P P ++W +G ++ +
Sbjct: 16919 KDLVIEPDVKPAF----SSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLK-QTTRINV 16973
Query: 116 VSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
L +L + D G Y N G+ T ++++ L K
Sbjct: 16974 TDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK 17017
Score = 34.3 bits (77), Expect = 0.15
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 3/69 (4%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGL-HSLIFEVVRA 131
+++++ EG ++ KVS V WYLN ++ DD + IV KG L+ A
Sbjct: 2406 KDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIV--KGTKQRLVINRTHA 2463
Query: 132 SDAGAYACV 140
SD G Y +
Sbjct: 2464 SDEGPYKLI 2472
Score = 34.3 bits (77), Expect = 0.15
Identities = 27/126 (21%), Positives = 55/126 (43%), Gaps = 12/126 (9%)
Query: 69 IQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEV 128
++ + + + G R++ VSG P P + W +G+ ++ ++ +++ +L+ +
Sbjct: 15160 VKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKD 15218
Query: 129 VRASDAGAYACVAKNRAGEATFTVQLDVLAKE-HKRAPMFIYKPQSKKVLEGDSVKLECQ 187
D+GAY A N G A + VL + P+ + + S+K C
Sbjct: 15219 STRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEK----------CV 15268
Query: 188 ISAIPP 193
+S PP
Sbjct: 15269 LSWFPP 15274
Score = 34.3 bits (77), Expect = 0.15
Identities = 20/85 (23%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V G+ +K+ I+ P P + W ++ ++ + DN L +KD ++D G
Sbjct: 19496 VKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDN--HTLLTVKDCIRRDTG 19553
Query: 236 WYTVSAVNEAGVTTCNTRLDVTARP 260
Y ++ N AG + V +P
Sbjct: 19554 QYVLTLKNVAGTRSVAVNCKVLDKP 19578
Score = 33.9 bits (76), Expect = 0.19
Identities = 39/137 (28%), Positives = 60/137 (43%), Gaps = 11/137 (8%)
Query: 178 EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD-AGW 236
EGD V L I+ ++ W N++V + L NT TL+I VN +D G
Sbjct: 4448 EGDIVHLTTSITNAK--EVNWYFENKLVPSDEKFKCLQDQNT--YTLVIDKVNTEDHQGE 4503
Query: 237 YTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGLNVKQAFNPE 296
Y A+N++G T + +L V R P K+ ++ P L ++ A P
Sbjct: 4504 YVCEALNDSGKTATSAKLTVVKR---AAPVIKR-KIEPLEVALGHLAKFTCEIQSA--PN 4557
Query: 297 GEFQRLAAQSGLYESEE 313
FQ A +YES++
Sbjct: 4558 VRFQWFKAGREIYESDK 4574
Score = 33.9 bits (76), Expect = 0.19
Identities = 22/94 (23%), Positives = 37/94 (39%), Gaps = 4/94 (4%)
Query: 172 QSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNK 231
Q+ V G S++L P P W + + + D TL +++ N+
Sbjct: 22060 QTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRAD----IHTTDSFSTLTVENCNR 22115
Query: 232 KDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLP 265
DAG YT++ N +G + + V P P
Sbjct: 22116 NDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGP 22149
Score = 33.5 bits (75), Expect = 0.25
Identities = 36/159 (22%), Positives = 62/159 (38%), Gaps = 16/159 (10%)
Query: 14 VFQAQDDSGAQDSQQHNSEHARLQVP------TSQVRSRSTSRGDVNDQDAIQEKFYPPR 67
V +A D+ + + N + R +V Q R + ++ +D + +K YP
Sbjct: 13322 VKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKD 13381
Query: 68 FIQVPEN---------MSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSE 118
+ PE + + G R+ V G P P ++W ++ D + I S
Sbjct: 13382 ILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLR-DRIGLDIKST 13440
Query: 119 KGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
L E V DAG Y +N G+ +T+ + VL
Sbjct: 13441 DFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVL 13479
Score = 33.1 bits (74), Expect = 0.33
Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V G +V+ I +P P W + ++ + + ++ DN V L IK+ ++D G
Sbjct: 11217 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTD-EHYTVETDNFSSV-LTIKNCLRRDTG 11274
Query: 236 WYTVSAVNEAGVTTCNTRLDVTARP 260
Y ++ N AG T L V P
Sbjct: 11275 EYQITVSNAAGSKTVAVHLTVLDVP 11299
Score = 33.1 bits (74), Expect = 0.33
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 1/95 (1%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP F + ++ G ++D G P P V+W+ + ++ +E
Sbjct: 15842 PPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLT 15901
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
I + R D G Y N AGEA T+ + VL K
Sbjct: 15902 IKDACR-EDVGHYVVKLTNSAGEAIETLNVIVLDK 15935
Score = 32.7 bits (73), Expect = 0.43
Identities = 26/104 (25%), Positives = 44/104 (42%), Gaps = 6/104 (5%)
Query: 59 IQEKFYPPRFI---QVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMI 115
++++ PP I + I G R+ + G+P P V+W R + ++
Sbjct: 10904 VKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTK--ARID 10961
Query: 116 VSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
V+ G L D G Y+ +N AG T +V++ VL K
Sbjct: 10962 VTPVG-SKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDK 11004
Score = 32.7 bits (73), Expect = 0.43
Identities = 22/95 (23%), Positives = 38/95 (40%), Gaps = 7/95 (7%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P + I VP GR + ++G P P SW+ G ++ + + + + L
Sbjct: 23439 PQKTIHVPA------GRPVELVIPIAGRPPPAASWFFAGSKLRESE-RVTVETHTKVAKL 23491
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
D G Y KN G + T+++ +L K
Sbjct: 23492 TIRETTIRDTGEYTLELKNVTGTTSETIKVIILDK 23526
Score = 32.0 bits (71), Expect = 0.73
Identities = 30/134 (22%), Positives = 44/134 (32%), Gaps = 9/134 (6%)
Query: 32 EHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYPP----RFIQVPENMSIDEGRFCRMDF 87
EH + V S + IQ+ PP R + + + G +
Sbjct: 9056 EHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPA 9115
Query: 88 KVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS-----LIFEVVRASDAGAYACVAK 142
V+GLP P + W N ++ I E+ S L D G Y A
Sbjct: 9116 DVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTAS 9175
Query: 143 NRAGEATFTVQLDV 156
NR G V ++V
Sbjct: 9176 NRLGSVFRNVHVEV 9189
Score = 32.0 bits (71), Expect = 0.73
Identities = 33/126 (26%), Positives = 58/126 (46%), Gaps = 8/126 (6%)
Query: 181 SVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIK-DVNKKDAGWYTV 239
+++L I P P++ W R++ + D+ S+ ++T TLLI +VN+ D+G Y +
Sbjct: 15572 TLRLFVPIKGRPAPEVKWARDHGE---SLDKASI--ESTSSYTLLIVGNVNRFDSGKYIL 15626
Query: 240 SAVNEAGVTTC--NTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGLNVKQAFNPEG 297
+ N +G + N R+ T P Q L + + T + L G +K +
Sbjct: 15627 TVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKR 15686
Query: 298 EFQRLA 303
E R A
Sbjct: 15687 ESTRKA 15692
Score = 31.6 bits (70), Expect = 0.96
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 89 VSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEA 148
+ G P P SW G+ ++ D+ I S L + DAG Y A N G
Sbjct: 14098 ILGKPLPKSSWSKAGKDIRPSDI-TQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTK 14156
Query: 149 TFTVQLDVLAKEHKRAPMFIYKPQSKK 175
V++ VL P+ I ++K
Sbjct: 14157 VEHVKVTVLDVPGPPGPVEISNVSAEK 14183
Score = 31.6 bits (70), Expect = 0.96
Identities = 26/109 (23%), Positives = 46/109 (42%), Gaps = 6/109 (5%)
Query: 52 DVNDQDAIQEKFYPPRF---IQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQS 108
DV ++EK P +++ + ++I G R+ + G P P+V W G+
Sbjct: 16621 DVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKW---GKVDGE 16677
Query: 109 DDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
+I SL+ + V D+G Y +N +G + V + VL
Sbjct: 16678 IRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVL 16726
Score = 31.6 bits (70), Expect = 0.96
Identities = 20/82 (24%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G V+L I+ PPP W ++ ++R+++ + +T L I++ +D G YT
Sbjct: 23448 GRPVELVIPIAGRPPPAASWFFAGSKLR-ESERVTV-ETHTKVAKLTIRETTIRDTGEYT 23505
Query: 239 VSAVNEAGVTTCNTRLDVTARP 260
+ N G T+ ++ + +P
Sbjct: 23506 LELKNVTGTTSETIKVIILDKP 23527
Score = 30.8 bits (68), Expect = 1.6
Identities = 32/153 (20%), Positives = 60/153 (39%), Gaps = 7/153 (4%)
Query: 96 DVSWYLNGRTVQSDDLHKMIVSEKG-LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQL 154
DV+W G ++ + K S+ G + L V+ D G Y+C+ N GE T + L
Sbjct: 3519 DVTWTHEGAKIEESERLKQ--SQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVL 3576
Query: 155 DVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDR--- 211
V I + ++ E S L + + +L + NE ++ ++
Sbjct: 3577 SVEGAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVY 3636
Query: 212 -ISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
+ G + IK+V+ D V+ ++
Sbjct: 3637 PTKFDSEKEGTGPIFIKEVSNADISMGDVATLS 3669
Score = 30.8 bits (68), Expect = 1.6
Identities = 23/87 (26%), Positives = 37/87 (42%), Gaps = 14/87 (16%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT-----LLIKDVNKKD 233
G +++ +S PPP + W N +L Q+ T T ++IK+ +
Sbjct: 10234 GGVIRIIAYVSGKPPPTVTWNMNER---------TLPQEATIETTAISSSMVIKNCQRSH 10284
Query: 234 AGWYTVSAVNEAGVTTCNTRLDVTARP 260
G Y++ A NEAG +DV P
Sbjct: 10285 QGVYSLLAKNEAGERKKTIIVDVLDVP 10311
Score = 30.4 bits (67), Expect = 2.1
Identities = 24/105 (22%), Positives = 43/105 (40%), Gaps = 13/105 (12%)
Query: 90 SGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEAT 149
+G P P +W + +++ D KM + L+ SD G Y +NR +
Sbjct: 7114 TGYPRPTATWCFGDKVLETGDRVKM-KTLSAYAELVISPSERSDKGIYTLKLENRVKTIS 7172
Query: 150 FTVQLDVLAKEHKRAPMFIYKPQSKKVLE-GDSVKLECQISAIPP 193
+ ++V+A +P + K L+ GD K ++ PP
Sbjct: 7173 GEIDVNVIA-----------RPSAPKELKFGDITKDSVHLTWEPP 7206
Score = 30.4 bits (67), Expect = 2.1
Identities = 25/113 (22%), Positives = 45/113 (39%), Gaps = 5/113 (4%)
Query: 47 STSRGDVNDQDAIQ--EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGR 104
S S G + +D I P++ V + + G ++ + G P PDV W +G+
Sbjct: 18385 SDSSGAITARDEIDAPNASLDPKYKDV---IVVHAGETFVLEADIRGKPIPDVVWSKDGK 18441
Query: 105 TVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
++ I S +L+ + +D G Y N G + + + VL
Sbjct: 18442 ELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVL 18494
Score = 30.0 bits (66), Expect = 2.8
Identities = 25/96 (26%), Positives = 48/96 (50%), Gaps = 7/96 (7%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLL-IKDVNKKDAGWY 237
G+ V++ PPP + W+++ + + + R S+ +NT +LL I V + D G Y
Sbjct: 20981 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSDA-RYSI--ENTDSSSLLTIPQVTRNDTGKY 21037
Query: 238 TVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVR 273
++ N G +T V+ + T A ++L+V+
Sbjct: 21038 ILTIENGVGEPKSST---VSVKVLDTPAACQKLQVK 21070
Score = 30.0 bits (66), Expect = 2.8
Identities = 16/61 (26%), Positives = 26/61 (42%), Gaps = 2/61 (3%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G +V LE P P + W ++ + + ++TL IK+ K+ G YT
Sbjct: 21273 GHNVHLELPYKGKPKPSISWLKDG--LPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT 21330
Query: 239 V 239
V
Sbjct: 21331 V 21331
Score = 29.6 bits (65), Expect = 3.6
Identities = 24/102 (23%), Positives = 42/102 (41%), Gaps = 8/102 (7%)
Query: 60 QEKFYPPRFIQVPENMSIDEGRFC---RMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIV 116
+++ PP + + R C R+ + G PAP+V W + + L K +
Sbjct: 15547 EDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARD----HGESLDKASI 15602
Query: 117 SEKGLHS-LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
++ LI V D+G Y +N +G + V + VL
Sbjct: 15603 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVL 15644
Score = 29.6 bits (65), Expect = 3.6
Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 3/84 (3%)
Query: 75 MSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL-IFEVVRASD 133
++I G +D V G P P + W + + D K+ + G + + + SD
Sbjct: 22752 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKEL--DLCEKVSLQYTGKRATAVIKFCDRSD 22809
Query: 134 AGAYACVAKNRAGEATFTVQLDVL 157
+G Y KN +G +V + VL
Sbjct: 22810 SGKYTLTVKNASGTKAVSVMVKVL 22833
Score = 29.3 bits (64), Expect = 4.7
Identities = 18/86 (20%), Positives = 37/86 (43%), Gaps = 4/86 (4%)
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V +G ++L I P P W + + + + ++ + L+IK+ ++ D+G
Sbjct: 23843 VRQGGVIRLTIPIKGKPFPICKWTKEGQDIS----KRAMIATSETHTELVIKEADRGDSG 23898
Query: 236 WYTVSAVNEAGVTTCNTRLDVTARPN 261
Y + N+ G ++ V PN
Sbjct: 23899 TYDLVLENKCGKKAVYIKVRVIGSPN 23924
Score = 28.9 bits (63), Expect = 6.2
Identities = 33/112 (29%), Positives = 44/112 (39%), Gaps = 26/112 (23%)
Query: 89 VSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI----FEVVRAS---DAGAYACVA 141
V G PAP V+W R V D+ V KG L+ F V+ S D+G Y+
Sbjct: 12325 VRGRPAPKVTW----RKVGIDN-----VVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTL 12375
Query: 142 KNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPP 193
N AGE V + VL + + + D K C +S PP
Sbjct: 12376 VNPAGEKAVFVNVRVLDTPGPVSDLKV----------SDVTKTSCHVSWAPP 12417
Score = 28.5 bits (62), Expect = 8.1
Identities = 26/125 (20%), Positives = 48/125 (38%), Gaps = 6/125 (4%)
Query: 35 RLQVPTSQVRSRSTSRGDVNDQDAIQ--EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGL 92
RLQ+ + R + R D++A E P+ +++ +D G+ M
Sbjct: 6662 RLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAY 6721
Query: 93 PAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTV 152
P + W+ + + K I + S + D G Y V +N+ G+A +
Sbjct: 6722 PKAEAEWFKENEPLST----KTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFI 6777
Query: 153 QLDVL 157
L V+
Sbjct: 6778 NLKVI 6782
Score = 28.5 bits (62), Expect = 8.1
Identities = 19/73 (26%), Positives = 31/73 (42%), Gaps = 1/73 (1%)
Query: 84 RMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKN 143
+++ V G P P V+W + ++ + I E VR SD+G Y A+N
Sbjct: 14779 KVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVR-SDSGPYPLTARN 14837
Query: 144 RAGEATFTVQLDV 156
GE + + V
Sbjct: 14838 IVGEVGDVITIQV 14850
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 127 bits (320), Expect = 1e-29
Identities = 66/216 (30%), Positives = 115/216 (53%)
Query: 61 EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKG 120
E+ Y P F+ P + EG+ R D KV G P P+ W+ +G+ + +D HK+++ E G
Sbjct: 1406 ERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDG 1465
Query: 121 LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGD 180
SLI SD+G + VA+NRAG ++ +V L V A EH+ PMF+ K ++ + EG
Sbjct: 1466 TQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGS 1525
Query: 181 SVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVS 240
++++ + + P P + W +N++++ + + G L I +D+ WYT +
Sbjct: 1526 RLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTAT 1585
Query: 241 AVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTF 276
A+N+AG T +++V + P K + R T+
Sbjct: 1586 AINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTY 1621
Score = 95.9 bits (237), Expect = 4e-20
Identities = 62/198 (31%), Positives = 92/198 (46%), Gaps = 7/198 (3%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIV--SEKGLH 122
PP F N + G R ++ P P V+WY +G+ ++ D K S+KGL+
Sbjct: 25317 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY 25376
Query: 123 SLIFEVVRASDAGAYACVAKNRAGE----ATFTVQLDVLAKEHKRAPMFIYKPQSKKVLE 178
L V D Y VA+N+ GE A TV L + PMF + + E
Sbjct: 25377 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQE 25436
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G SV E ++S IPPP L W+++ + + + I + + L I+D +D G+Y
Sbjct: 25437 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPN-IEIIHEGLDYYALHIRDTLPEDTGYYR 25495
Query: 239 VSAVNEAGVTTCNTRLDV 256
V+A N AG T+C L V
Sbjct: 25496 VTATNTAGSTSCQAHLQV 25513
Score = 92.8 bits (229), Expect = 3e-19
Identities = 62/213 (29%), Positives = 109/213 (51%), Gaps = 13/213 (6%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVS-EKGLHSL 124
P F Q +++ + EG + +SG P P+VSW+ +G+ + + L + +S G L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
V +++G Y+ A N +G+AT T +L L K P F+ + QS V +G V+L
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAEL--LVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTD-RISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
+ +++ IP P + + R+ +Q + D +IS D +LLI + +D+G Y+V+A N
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGD---LYSLLIAEAYPEDSGTYSVNATN 180
Query: 244 EAGVTTCNTRL------DVTARPNQTLPAPKQL 270
G T L +V A+ +T+ + Q+
Sbjct: 181 SVGRATSTAELLVQGEEEVPAKKTKTIVSTAQI 213
Score = 88.6 bits (218), Expect = 7e-18
Identities = 68/278 (24%), Positives = 121/278 (43%), Gaps = 31/278 (11%)
Query: 64 YPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS 123
YPP I ++ EG+ R +VSG VSWY + ++ +M E
Sbjct: 3297 YPPAIITPLQDTVTSEGQPARFQCRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFEDTYQL 3355
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDV------------------LAKEHKRAP 165
I E D G Y VA N G+ + T L + L+ K+ P
Sbjct: 3356 EIAEAY-PEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEP 3414
Query: 166 M-----FIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTG 220
+ FI S +V G++V+ ++S IP P++ W N +++ D + ++++TG
Sbjct: 3415 LGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTG 3474
Query: 221 RVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPK-----QLRVRPT 275
+LI D + AG Y+ A N AG TC L VT + +++ + ++ ++
Sbjct: 3475 MALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEMEMKEF 3534
Query: 276 FSKYLALNGKGL-NVKQAFNPEGEFQRLAAQSGLYESE 312
S +L+ +GL + + + E L ++S +Y ++
Sbjct: 3535 SSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTK 3572
Score = 84.7 bits (208), Expect = 1e-16
Identities = 60/231 (25%), Positives = 94/231 (40%), Gaps = 42/231 (18%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP + +N+++ EG ++ +SG P+P V+WY ++S + I + G+ L
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESS-IDFQITFQSGIARL 954
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDV----------------LAKEHKR----- 163
+ A D+G + C A N AG + + L V E KR
Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014
Query: 164 --------------------APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNE 203
AP FI KP +K++EG SV CQ+ P P ++WK++
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1074
Query: 204 MVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRL 254
+ Y TG L+I DAG YT+ N+ G T+ + L
Sbjct: 1075 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 78.6 bits (192), Expect = 7e-15
Identities = 55/182 (30%), Positives = 94/182 (51%), Gaps = 6/182 (3%)
Query: 75 MSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDA 134
MSI+EG+ R+ K + A DV W LNG + + + ++ VS +L + D
Sbjct: 26676 MSINEGQ--RLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSD-QTLTIKQASHRDE 26732
Query: 135 GAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPP 194
G C++K + G L L+KE AP FI +P+S+ + EG +V C+IS P P
Sbjct: 26733 GILTCISKTKEGIVKCQYDL-TLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSP 26791
Query: 195 KLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRL 254
++ W +NN + +++ +S+ + + +L I++ + D+G YT+ A N G + L
Sbjct: 26792 EIEWFKNNLPISISSN-VSISR-SRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASL 26849
Query: 255 DV 256
V
Sbjct: 26850 MV 26851
Score = 77.8 bits (190), Expect = 1e-14
Identities = 53/197 (26%), Positives = 83/197 (42%), Gaps = 2/197 (1%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKG-LHSL 124
P F + N+++ + KV+G P P V WY G+ + +D L I KG H L
Sbjct: 24556 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24615
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
I V DA Y A N+ G + T L+V P + + L G+ V +
Sbjct: 24616 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSI 24675
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
+ S P P + W++ +++ N + + + V +KDAG+Y V A N
Sbjct: 24676 KIPFSGKPDPVITWQKGQDLID-NNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNR 24734
Query: 245 AGVTTCNTRLDVTARPN 261
G+ LDV P+
Sbjct: 24735 FGIDQKTVELDVADVPD 24751
Score = 69.3 bits (168), Expect = 4e-12
Identities = 53/229 (23%), Positives = 88/229 (38%), Gaps = 22/229 (9%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P FI+ N I G + V G+P P + W+ NG + +K + HSLI
Sbjct: 3582 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDD-HSLI 3640
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK--EHKRA------------------P 165
+ D G Y C+A N G+ + L + +K HK P
Sbjct: 3641 ILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPP 3700
Query: 166 MFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLL 225
F+ + + + +G E + P P + W + N+ + + ++ N G T +
Sbjct: 3701 HFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPN-GSGTFI 3759
Query: 226 IKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRP 274
+ D ++D+G Y A N G +TC L V P + + P
Sbjct: 3760 VNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTP 3808
Score = 65.5 bits (158), Expect = 6e-11
Identities = 60/254 (23%), Positives = 116/254 (45%), Gaps = 21/254 (8%)
Query: 7 GPQNAAAVFQAQDDS--GAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFY 64
G +A + QD+S +++ ++ +SE +V T +++ + G + +D
Sbjct: 4317 GVASAVVSDEKQDESLKPSEEKEESSSESGTEEVATVKIQE---AEGGLIKEDG------ 4367
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P + + +S +EG + ++ A +V+WY + V SD+ K + ++ ++L
Sbjct: 4368 PMIHTPLVDTVS-EEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCL-QDQNTYTL 4423
Query: 125 IFEVVRASD-AGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
+ + V D G Y C A N +G+ + +L V+ + AP+ K + +V G K
Sbjct: 4424 VIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVV---KRAAPVIKRKIEPLEVALGHLAK 4480
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
C+I + P + W + + + +D+ S+ + + +L I D G YT A N
Sbjct: 4481 FTCEIQSAPNVRFQWFKAGREI-YESDKCSI-RSSKYISSLEILRTQVVDCGEYTCKASN 4538
Query: 244 EAGVTTCNTRLDVT 257
E G +C L VT
Sbjct: 4539 EYGSVSCTATLTVT 4552
Score = 64.3 bits (155), Expect = 1e-10
Identities = 39/126 (30%), Positives = 64/126 (50%), Gaps = 1/126 (0%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP F+Q ++M++ +G R+ +V+G+P P V +Y +G +QS L I E L+SL
Sbjct: 103 PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQS-SLDFQISQEGDLYSL 161
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
+ D+G Y+ A N G AT T +L V +E A + ++ E ++
Sbjct: 162 LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRI 221
Query: 185 ECQISA 190
E +I A
Sbjct: 222 EKKIEA 227
Score = 62.0 bits (149), Expect = 7e-10
Identities = 52/176 (29%), Positives = 78/176 (44%), Gaps = 16/176 (9%)
Query: 96 DVSWYLNGRTV--QSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQ 153
D WY +G + Q + HK +V E+ +H + R SDAG Y V AG +V
Sbjct: 3130 DAHWYKDGIEINFQVQERHKYVV-ERRIHRMFISETRQSDAGEYTFV----AGRNRSSVT 3184
Query: 154 LDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRIS 213
L V A E P + + Q V G + IS P PK+ W + +++ +T
Sbjct: 3185 LYVNAPE---PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKC 3239
Query: 214 LYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV----TARPNQTLP 265
+ + TLL+ + +DA YT A N+ GV T + L V P+Q +P
Sbjct: 3240 KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP 3295
Score = 61.6 bits (148), Expect = 9e-10
Identities = 50/209 (23%), Positives = 84/209 (40%), Gaps = 30/209 (14%)
Query: 97 VSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDV 156
V+WY R +++ + ++ I E G+ L + + D G Y C N GE + +L V
Sbjct: 25228 VTWYFGVRQLENSEKYE-ITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25286
Query: 157 LAKEH-----------------------KRAPMFIYKPQSKKVLEGDSVKLECQISAIPP 193
+R P F +K G++V+ I+ P
Sbjct: 25287 KGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPE 25346
Query: 194 PKLFWKRNNEMVQ-FNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
P + W ++ + ++ + D+ ++ + G L I V D YTV A N+ G +C
Sbjct: 25347 PHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKA 25406
Query: 253 RLDVTARPNQTLPAPKQLRVRPTFSKYLA 281
+L VT P P +RP F + LA
Sbjct: 25407 KLTVTLH-----PPPTDSTLRPMFKRLLA 25430
Score = 61.2 bits (147), Expect = 1e-09
Identities = 48/200 (24%), Positives = 83/200 (41%), Gaps = 12/200 (6%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP+ +Q + +++ G+ R +SG P P +SWY + + + K + + L
Sbjct: 3192 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3251
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE--HKRAPMFIYKP------QSKKV 176
+ E DA Y C AKN G AT + L V E M +Y P Q
Sbjct: 3252 LIEAF-PEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVT 3310
Query: 177 LEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGW 236
EG + +C++S ++ ++ ++ R++ ++D L I + +D G
Sbjct: 3311 SEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDT---YQLEIAEAYPEDEGT 3367
Query: 237 YTVSAVNEAGVTTCNTRLDV 256
YT A N G + L +
Sbjct: 3368 YTFVASNAVGQVSSTANLSL 3387
Score = 60.8 bits (146), Expect = 1e-09
Identities = 47/185 (25%), Positives = 87/185 (47%), Gaps = 8/185 (4%)
Query: 80 GRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYAC 139
G ++ ++ G P PD+ WY G+ + +KM S+ H+L D G Y C
Sbjct: 24175 GEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKM-SSDGRTHTLTVMTEEQEDEGVYTC 24233
Query: 140 VAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWK 199
+A N GE + +L +L + P + K + + G +++L P P + W
Sbjct: 24234 IATNEVGEVETSSKL-LLQATPQFHPGYPLKEKYYGAV-GSTLRLHVMYIGRPVPAMTWF 24291
Query: 200 RNNEMVQFNTDRISLYQDNTGRVT-LLIKDVNKK-DAGWYTVSAVNEAGVTTCNTRLDVT 257
+++Q N++ I++ +NT T L++K+V +K AG Y V N G +++
Sbjct: 24292 HGQKLLQ-NSENITI--ENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQ 24348
Query: 258 ARPNQ 262
+P++
Sbjct: 24349 DKPDK 24353
Score = 60.1 bits (144), Expect = 3e-09
Identities = 36/117 (30%), Positives = 59/117 (50%), Gaps = 2/117 (1%)
Query: 140 VAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWK 199
V R + T T ++ + P + ++ V+EG+SV LEC IS P P + W
Sbjct: 872 VLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWY 931
Query: 200 RNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
R + ++ + D +Q R L+I++ +D+G +T SAVNEAG + + L V
Sbjct: 932 REDYQIESSIDFQITFQSGIAR--LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 59.7 bits (143), Expect = 3e-09
Identities = 62/264 (23%), Positives = 108/264 (40%), Gaps = 44/264 (16%)
Query: 51 GDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD 110
GD+ D++ Q+ F+ + + CR+ G P V W +G+ +++ +
Sbjct: 1646 GDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLT--PIGDPTMVVEWLHDGKPLEAAN 1703
Query: 111 LHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAG----EATFTV-------------- 152
+MI +E G SL + V + D+G C A N+ G AT V
Sbjct: 1704 RLRMI-NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPE 1762
Query: 153 ---------QLDVLAKE-----------HKRAPMFIYKPQSKKVLEGDSVKLECQISAIP 192
+L+ +A E K+ P + P+ +VLEG++ + C+++ P
Sbjct: 1763 GRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYP 1822
Query: 193 PPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
PK+ W N ++++ + R + D G L I D D G V+A N GV
Sbjct: 1823 QPKVNWYLNGQLIR-KSKRFRVRYD--GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKV 1879
Query: 253 RLDVTARPNQTLPAPKQLRVRPTF 276
+L++ R + + RP F
Sbjct: 1880 KLEIQQREDFRSVLRRAPEPRPEF 1903
Score = 58.2 bits (139), Expect = 1e-08
Identities = 46/166 (27%), Positives = 79/166 (47%), Gaps = 13/166 (7%)
Query: 74 NMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASD 133
N+ + E ++ +VS P +V WY + ++ I++E L+ + D
Sbjct: 6099 NIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYE-ILTEGRKRILVIQNAHLED 6156
Query: 134 AGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPP 193
AG Y C + + D K H+ A FI KPQ+ ++LEG+ + C IS
Sbjct: 6157 AGNYNCRLPSS--------RTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSISKESF 6208
Query: 194 PKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTV 239
P + WKR+++ ++ + D+ + D RV L++KD +D G Y V
Sbjct: 6209 P-VQWKRDDKTLE-SGDKYDVIADGKKRV-LVVKDATLQDMGTYVV 6251
Score = 55.5 bits (132), Expect = 6e-08
Identities = 34/125 (27%), Positives = 58/125 (46%), Gaps = 1/125 (0%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P FI P + +I+EG+ ++SG P+P++ W+ N + S + I + ++SL
Sbjct: 26762 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPI-SISSNVSISRSRNVYSLE 26820
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLE 185
SD+G Y AKN G+ + T L VL + + + + L+G
Sbjct: 26821 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQS 26880
Query: 186 CQISA 190
Q+SA
Sbjct: 26881 VQMSA 26885
Score = 54.3 bits (129), Expect = 1e-07
Identities = 35/102 (34%), Positives = 50/102 (49%), Gaps = 3/102 (2%)
Query: 163 RAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV 222
+AP F QS VLEG + E IS P P++ W R+ +++ +T + GR
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 223 TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV---TARPN 261
L I V K ++G Y++ A N +G T L V TA PN
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPN 105
Score = 54.3 bits (129), Expect = 1e-07
Identities = 33/129 (25%), Positives = 63/129 (48%), Gaps = 8/129 (6%)
Query: 141 AKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK----KVLEGDSVKLECQISAIPPPKL 196
A N GE+ ++ L+V+ ++ + P + + KV G+ V + ++ +P PK+
Sbjct: 8999 AVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKI 9058
Query: 197 FWKRNNEMVQFNTDRISLYQDNTGR----VTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
W +N +++ TD + + ++ R L I ++D G YTV+A N G N
Sbjct: 9059 EWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNV 9118
Query: 253 RLDVTARPN 261
++V RP+
Sbjct: 9119 HVEVYDRPS 9127
Score = 53.5 bits (127), Expect = 2e-07
Identities = 38/158 (24%), Positives = 66/158 (41%), Gaps = 4/158 (2%)
Query: 7 GPQNAAAVFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYPP 66
G + +A +D+ + Q LQ + R G + Q++ P
Sbjct: 1738 GTDHTSATLIVKDEKSLVEESQLPEGRKGLQ--RIEELERMAHEGALTGVTTDQKEKQKP 1795
Query: 67 RFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIF 126
+ PE + + EG R +V+G P P V+WYLNG+ ++ + V G+H L
Sbjct: 1796 DIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKS--KRFRVRYDGIHYLDI 1853
Query: 127 EVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRA 164
++ D G A+N G V+L++ +E R+
Sbjct: 1854 VDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRS 1891
Score = 53.1 bits (126), Expect = 3e-07
Identities = 43/153 (28%), Positives = 68/153 (44%), Gaps = 11/153 (7%)
Query: 117 SEKGLHSLIFEVVRASDAGAYACVAK--NRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK 174
+++ + L F V + G Y K N AG + + + + P I +
Sbjct: 9695 NKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFM 9754
Query: 175 KVLEGDSVKLECQISAIPPPKLFWKR-------NNEMVQFNTDRISLYQDNTGRVTLLIK 227
+V EG +V + +I +P P L W + N E V ++T L D+T TL+I
Sbjct: 9755 EVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDT--CTLVIP 9812
Query: 228 DVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARP 260
+ D G YT++AVN G + RL+V RP
Sbjct: 9813 QSRRSDTGLYTITAVNNLGTASKEMRLNVLGRP 9845
Score = 52.8 bits (125), Expect = 4e-07
Identities = 48/162 (29%), Positives = 72/162 (44%), Gaps = 11/162 (6%)
Query: 93 PAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTV 152
P V WY +G V D ++M S++ +H L + SDA Y+CV T T
Sbjct: 2155 PFVKVKWYKDGMEVHEGDKYRMH-SDRKVHFLSILTIDTSDAEDYSCVLVEDENVKT-TA 2212
Query: 153 QLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRI 212
+L V F+ + Q +V E S +LEC +S P + K + V+ ++
Sbjct: 2213 KLIV----EGAVVEFVKELQDIEVPESYSGELECIVS---PENIEGKWYHNDVELKSNGK 2265
Query: 213 SLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRL 254
GR L +KDV K+D G Y S V + TTC ++
Sbjct: 2266 YTITSRRGRQNLTVKDVTKEDQGEY--SFVIDGKKTTCKLKM 2305
Score = 52.8 bits (125), Expect = 4e-07
Identities = 40/147 (27%), Positives = 71/147 (48%), Gaps = 3/147 (2%)
Query: 115 IVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQ-LDVLAKEHKRAPMFIYKPQS 173
IV+E + + + + + + A N G++ V + V+AK+ P +
Sbjct: 17889 IVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNT 17948
Query: 174 KKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD 233
+ G+ +K+E + P P + W ++ E ++ T R+++ + T V L IK+ NK D
Sbjct: 17949 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLK-QTTRVNVEETATSTV-LHIKEGNKDD 18006
Query: 234 AGWYTVSAVNEAGVTTCNTRLDVTARP 260
G YTV+A N AG T N + V +P
Sbjct: 18007 FGKYTVTATNSAGTATENLSVIVLEKP 18033
Score = 52.4 bits (124), Expect = 5e-07
Identities = 32/143 (22%), Positives = 67/143 (46%), Gaps = 2/143 (1%)
Query: 123 SLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSV 182
SL+ ++ + A+N G + V + + P I P+ + G +
Sbjct: 12485 SLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKL 12544
Query: 183 KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAV 242
++E + P P WK+ + V + +++++ ++ + L+IKDV +KD+G+Y+++A
Sbjct: 12545 RIEAHVYGKPHPTCKWKKGEDEV-VTSSHLAVHKADSSSI-LIIKDVTRKDSGYYSLTAE 12602
Query: 243 NEAGVTTCNTRLDVTARPNQTLP 265
N +G T ++ V P P
Sbjct: 12603 NSSGTDTQKIKVVVMDAPGPPQP 12625
Score = 51.6 bits (122), Expect = 9e-07
Identities = 33/153 (21%), Positives = 65/153 (42%), Gaps = 6/153 (3%)
Query: 14 VFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFY------PPR 67
+F +D G N + ++ S+ D + A+ + PP
Sbjct: 3642 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 3701
Query: 68 FIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFE 127
F++ + + +G ++ V G PAP V+W+ + + + + +I + G + I
Sbjct: 3702 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 3761
Query: 128 VVRASDAGAYACVAKNRAGEATFTVQLDVLAKE 160
+ D+G Y C A+N GE+T +L VL ++
Sbjct: 3762 DPQREDSGLYICKAENMLGESTCAAELLVLLED 3794
Score = 51.2 bits (121), Expect = 1e-06
Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKM-IVSEKGLHS 123
PP+ +P ++SIDEG+ + +G P P+V+W GR + S + + I + L +
Sbjct: 26956 PPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTT 27015
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDV 156
LI V+ D G Y N G + TV + +
Sbjct: 27016 LIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27048
Score = 50.4 bits (119), Expect = 2e-06
Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 5/117 (4%)
Query: 52 DVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDL 111
D+++ +A++ F R +N I EG K+SG P P ++WY +G+ ++ +
Sbjct: 1236 DISESEAVESGF-DSRI----KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGER 1290
Query: 112 HKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFI 168
++M + G SL VV D G Y A N G A + +L V AP +I
Sbjct: 1291 YQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYI 1347
Score = 50.1 bits (118), Expect = 3e-06
Identities = 48/189 (25%), Positives = 83/189 (43%), Gaps = 14/189 (7%)
Query: 60 QEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVS---WYLNGRTVQSDDLHKMIV 116
Q K P +F++ +++ + E F L +P + W +G ++ H+ I
Sbjct: 4737 QLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIA 4796
Query: 117 SEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKK- 175
K I +V + SDAG Y CV + E T T +L V + P+ K ++
Sbjct: 4797 DGKDRKLHIIDV-QLSDAGEYTCVLRLGNKEKTSTAKLVV-----EELPVRFVKTLEEEV 4850
Query: 176 -VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDA 234
V++G + L C+++ + W+++ ++V RI R L I D + DA
Sbjct: 4851 TVVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMR-ALTINDADDTDA 4907
Query: 235 GWYTVSAVN 243
G YTV+ N
Sbjct: 4908 GTYTVTVEN 4916
Score = 49.7 bits (117), Expect = 3e-06
Identities = 48/179 (26%), Positives = 73/179 (40%), Gaps = 14/179 (7%)
Query: 68 FIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFE 127
FI P+N+ I EG +S P V W + +T++S D + +I K L+ +
Sbjct: 6182 FISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIADGKK-RVLVVK 6239
Query: 128 VVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQ 187
D G Y + G A L V+ K P+ + +V E V C+
Sbjct: 6240 DATLQDMGTYVVMV----GAARAAAHLTVIEKLRIVVPL-----KDTRVKEQQEVVFNCE 6290
Query: 188 ISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
++ K W RN E + ++ I L +D TL I+D + D Y VS N G
Sbjct: 6291 VNT-EGAKAKWFRNEEAIFDSSKYIILQKDLV--YTLRIRDAHLDDQANYNVSLTNHRG 6346
Score = 49.7 bits (117), Expect = 3e-06
Identities = 34/133 (25%), Positives = 64/133 (48%), Gaps = 10/133 (7%)
Query: 67 RFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIF 126
R + P +M++ EG R G P P V+W G+ + + H++ ++ + F
Sbjct: 26190 RILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK---YKSTF 26246
Query: 127 EV--VRASDAGAYACVAKNRAG----EATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGD 180
E+ V+ASD G Y+ V +N G E T T+Q + ++ +P + P+ +V +
Sbjct: 26247 EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPE-PRVKSPE 26305
Query: 181 SVKLECQISAIPP 193
+VK ++ + P
Sbjct: 26306 AVKSPKRVKSPEP 26318
Score = 49.3 bits (116), Expect = 4e-06
Identities = 45/200 (22%), Positives = 85/200 (42%), Gaps = 17/200 (8%)
Query: 72 PENMSI-DEGR------FCRMDFKVSGLPAPDVSWYLNGRTVQSDD---LHKMIVSEKGL 121
PEN+ I D+G+ + R D+ +P++S+++ R SDD +HK + E
Sbjct: 11732 PENLHIADKGKTFVYLKWRRPDYDGG---SPNLSYHVERRLKGSDDWERVHKGSIKET-- 11786
Query: 122 HSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLE-GD 180
H ++ V + + KN GE+ + +V+ KE + P+ K ++ GD
Sbjct: 11787 HYMVDRCVE-NQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGD 11845
Query: 181 SVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVS 240
+++LE + P P++ W ++ + + + D G Y V+
Sbjct: 11846 TIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVT 11905
Query: 241 AVNEAGVTTCNTRLDVTARP 260
A N AG ++V +P
Sbjct: 11906 ATNTAGSFVAYATVNVLDKP 11925
Score = 48.5 bits (114), Expect = 8e-06
Identities = 50/182 (27%), Positives = 83/182 (45%), Gaps = 21/182 (11%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKG-LHSLIFEVVRA 131
+++++ G D ++S P V WYL G+ ++ D K++ +G +H+L V+
Sbjct: 5831 KDVTVTAGETATFDCELSYEDIP-VEWYLKGKKLEPSD--KVVPRSEGKVHTLTLRDVKL 5887
Query: 132 SDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKP-QSKKVLEGDSVKLECQISA 190
DAG AK+ A V K P+ KP + + V EG + LEC++S
Sbjct: 5888 EDAGEVQLTAKDFKTHANLFV---------KEPPVEFTKPLEDQTVEEGATAVLECEVSR 5938
Query: 191 IPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV-TLLIKDVNKKDAGWYTVSAVNEAGVTT 249
K+ W +N + + + + D GRV L+I D +D YT A + T+
Sbjct: 5939 -ENAKVKWFKNGTEI-LKSKKYEIVAD--GRVRKLVIHDCTPEDIKTYTCDAKDFK--TS 5992
Query: 250 CN 251
CN
Sbjct: 5993 CN 5994
Score = 48.5 bits (114), Expect = 8e-06
Identities = 33/111 (29%), Positives = 55/111 (49%), Gaps = 8/111 (7%)
Query: 51 GDVNDQDAIQEKFYPPRF---IQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTV- 106
G+V D ++++ P V + + + G R+ VSG P P V+W +N RT+
Sbjct: 10135 GEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLP 10194
Query: 107 QSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
Q + +S S++ + + S G Y+ +AKN AGE T+ +DVL
Sbjct: 10195 QEATIETTAISS----SMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVL 10241
Score = 47.4 bits (111), Expect = 2e-05
Identities = 32/114 (28%), Positives = 56/114 (49%), Gaps = 3/114 (2%)
Query: 175 KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDA 234
++LEG V C++S P PK+ W ++ + ++ + +R + GR +L I V +D
Sbjct: 1255 RILEGMGVTFHCKMSGYPLPKIAWYKDGKRIK-HGERYQMDFLQDGRASLRIPVVLPEDE 1313
Query: 235 GWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGLN 288
G YT A N G C+ +L V P L AP + S+ +L+ + ++
Sbjct: 1314 GIYTAFASNIKGNAICSGKLYV--EPAAPLGAPTYIPTLEPVSRIRSLSPRSVS 1365
Score = 47.4 bits (111), Expect = 2e-05
Identities = 47/196 (23%), Positives = 80/196 (40%), Gaps = 7/196 (3%)
Query: 55 DQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKM 114
D+ + P+ + ++ ++ +G +V G P P+ WY NG ++ D
Sbjct: 2021 DKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYW 2080
Query: 115 IVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK 174
E + L+ V A D+ + A N AGE + L V AK+ F + Q
Sbjct: 2081 YWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ---LITFTQELQDV 2137
Query: 175 KVLEGDSV-KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD 233
E D++ EC+ S P K+ W ++ M D+ ++ D L I ++ D
Sbjct: 2138 VAKEKDTMATFECETSE-PFVKVKWYKDG-MEVHEGDKYRMHSDRKVHF-LSILTIDTSD 2194
Query: 234 AGWYTVSAVNEAGVTT 249
A Y+ V + V T
Sbjct: 2195 AEDYSCVLVEDENVKT 2210
Score = 47.4 bits (111), Expect = 2e-05
Identities = 30/82 (36%), Positives = 42/82 (51%), Gaps = 2/82 (2%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G ++ IS P PK+ WK EM TDR+S+ R TL +KD + D+G Y
Sbjct: 22290 GSPFTIDVPISGRPAPKVTWKLE-EMRLKETDRVSI-TTTKDRTTLTVKDSMRGDSGRYF 22347
Query: 239 VSAVNEAGVTTCNTRLDVTARP 260
++ N AGV T + + V RP
Sbjct: 22348 LTLENTAGVKTFSVTVVVIGRP 22369
Score = 46.6 bits (109), Expect = 3e-05
Identities = 42/141 (29%), Positives = 74/141 (52%), Gaps = 14/141 (9%)
Query: 99 WYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLA 158
WY N ++S+ + I S +G +L + V D G Y+ V + + T +++
Sbjct: 2253 WYHNDVELKSNGKYT-ITSRRGRQNLTVKDVTKEDQGEYSFVIDGK--KTTCKLKM---- 2305
Query: 159 KEHKRAPMFIYKPQS-KKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQD 217
K P+ I + S +KV EGD V+LE ++S + + W ++ + VQ +DR+ + D
Sbjct: 2306 ---KPRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQ-PSDRVHIVID 2360
Query: 218 NTGRVTLLIKDVNKKDAGWYT 238
+ LLI+D+ K+DAG Y+
Sbjct: 2361 KQSHM-LLIEDMTKEDAGNYS 2380
Score = 46.6 bits (109), Expect = 3e-05
Identities = 41/178 (23%), Positives = 79/178 (44%), Gaps = 15/178 (8%)
Query: 67 RFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIF 126
+ I+ P++++ E + VS P V W+ ++ D H++ VSE+ +H L+
Sbjct: 2750 KIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRL-VSERKVHKLML 2807
Query: 127 EVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLEC 186
+ + SDAG Y V +A V+ + K K I P++K + EC
Sbjct: 2808 QNISPSDAGEYTAVVGQLECKAKLFVETLHITKTMKN----IEVPETK------TASFEC 2857
Query: 187 QISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
++S P + W +N ++ + + Q + L+I + + +D+ YT N+
Sbjct: 2858 EVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQ--LIIMNTSTEDSAEYTFVCGND 2912
Score = 46.6 bits (109), Expect = 3e-05
Identities = 40/148 (27%), Positives = 68/148 (45%), Gaps = 12/148 (8%)
Query: 41 SQVRSRSTSRGDVN--------DQDAIQEKFYPPRF---IQVPENMSIDEGRFCRMDFKV 89
+Q + R+ +R VN D I + PPR + + +++ G +D V
Sbjct: 12888 AQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATV 12947
Query: 90 SGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEAT 149
G P P VSW +G ++ + KM + ++ L +L V D+G Y A+N +G +
Sbjct: 12948 FGKPMPTVSWKKDGTLLKPAEGIKMAM-QRNLCTLELFSVNRKDSGDYTITAENSSGSKS 13006
Query: 150 FTVQLDVLAKEHKRAPMFIYKPQSKKVL 177
T++L VL K A + I K S + +
Sbjct: 13007 ATIKLKVLDKPGPPASVKINKMYSDRAM 13034
Score = 46.2 bits (108), Expect = 4e-05
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 6/123 (4%)
Query: 141 AKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQISAIPPPKLF 197
A+N GE T + ++ V+A++ AP K E + +L+ I P P +
Sbjct: 13585 AENENGEGTPS-EITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVS 13643
Query: 198 WKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVT 257
WK+ + + +T R+S+ + + TL++ D K DAG YT++ N AG + V
Sbjct: 13644 WKKGEDPLATDT-RVSV-ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVV 13701
Query: 258 ARP 260
+P
Sbjct: 13702 GKP 13704
Score = 45.4 bits (106), Expect = 6e-05
Identities = 49/180 (27%), Positives = 84/180 (46%), Gaps = 25/180 (13%)
Query: 66 PRFIQVPENMS---IDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ-SDDLHKMIVSEKGL 121
PR I + + +S + EG +++ KVS L + + W +G+ VQ SD +H IV +K
Sbjct: 2307 PRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVH--IVIDKQS 2363
Query: 122 HSLIFEVVRASDAGAYA----CVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL 177
H L+ E + DAG Y+ + + +G + +DV+ P+ + V+
Sbjct: 2364 HMLLIEDMTKEDAGNYSFTIPALGLSTSGRVS-VYSVDVIT------PL-----KDVNVI 2411
Query: 178 EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
EG LEC++S + W N+E ++ DR+ T + L+I + D G Y
Sbjct: 2412 EGTKAVLECKVSVPDVTSVKWYLNDEQIK-PDDRVQAIVKGT-KQRLVINRTHASDEGPY 2469
Score = 45.1 bits (105), Expect = 8e-05
Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP + QS+ V +G ++ P P+ W +N ++ +DRI Y
Sbjct: 2031 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIE-RSDRIYWYWPEDNVCE 2089
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 259
L+I+DV +D+ V A+N AG T+ + L V A+
Sbjct: 2090 LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2125
Score = 45.1 bits (105), Expect = 8e-05
Identities = 41/174 (23%), Positives = 71/174 (40%), Gaps = 19/174 (10%)
Query: 79 EGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYA 138
EG + +P P VSW+ +G+ V++ D M H + + VRA DAG Y
Sbjct: 8028 EGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRA-DAGIYT 8086
Query: 139 CVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPP----- 193
+N+ G AT ++ + V+ K + D K C+++ PP
Sbjct: 8087 ITLENKLGSATASINVKVIG----------LPGPCKDIKASDITKSSCKLTWEPPEFDGG 8136
Query: 194 -PKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
P L + T + +N +++ +KD+ ++ V AVN+ G
Sbjct: 8137 TPILHYVLERREAGRRTYIPVMSGEN--KLSWTVKDLIPNGEYFFRVKAVNKVG 8188
Score = 45.1 bits (105), Expect = 8e-05
Identities = 24/86 (27%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Query: 175 KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDA 234
K G SVKL IS P P + W ++++ +Q T+ + ++ T ++LIKD ++ ++
Sbjct: 20511 KYRAGTSVKLRAGISGKPAPTIEWYKDDKELQ--TNALVCVENTTDLASILIKDADRLNS 20568
Query: 235 GWYTVSAVNEAGVTTCNTRLDVTARP 260
G Y + N G + R+ + +P
Sbjct: 20569 GCYELKLRNAMGSASATIRVQILDKP 20594
Score = 44.3 bits (103), Expect = 1e-04
Identities = 52/193 (26%), Positives = 79/193 (40%), Gaps = 18/193 (9%)
Query: 67 RFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIF 126
+F+ E+ ++ EG ++S V W+ N + + +I SE H L
Sbjct: 5203 KFMSPLEDQTVKEGETATFVCELSH-EKMHVVWFKNDAKLHTSRT-VLISSEGKTHKLEM 5260
Query: 127 EVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLEC 186
+ V D K E + T QL VL + P F K K +E D + L+C
Sbjct: 5261 KEVTLDDISQIKAQVK----ELSSTAQLKVLEAD----PYFTVKLHDKTAVEKDEITLKC 5312
Query: 187 QISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
++S P K F K E+V + + S+ D R+ L IK + KD G Y V + G
Sbjct: 5313 EVSKDVPVKWF-KDGEEIVP--SPKYSIKADGLRRI-LKIKKADLKDKGEY----VCDCG 5364
Query: 247 VTTCNTRLDVTAR 259
+ V AR
Sbjct: 5365 TDKTKANVTVEAR 5377
Score = 44.3 bits (103), Expect = 1e-04
Identities = 27/101 (26%), Positives = 43/101 (42%), Gaps = 4/101 (3%)
Query: 60 QEKFYPPRF---IQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIV 116
QEK PP +++ E + + G R + G+P P W +G +++D+ H +
Sbjct: 11130 QEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDE-HYTVE 11188
Query: 117 SEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
++ L + D G Y N AG T V L VL
Sbjct: 11189 TDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVL 11229
Score = 44.3 bits (103), Expect = 1e-04
Identities = 36/144 (25%), Positives = 67/144 (46%), Gaps = 4/144 (2%)
Query: 119 KGLHSLIFEVVRASDAGAYACVAKNRAGEAT-FTVQLDVLAKEHKRAPMFIYKPQSKKVL 177
K L ++I + + + + VA N G + ++ + ++AK+ P S V
Sbjct: 16812 KSLQAVITNLTQGEEY-LFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQ 16870
Query: 178 EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
G +K+E IS P P + W ++ ++ T RI++ D+ TL IK+ +K D G Y
Sbjct: 16871 VGQDLKIEVPISGRPKPTITWTKDGLPLK-QTTRINV-TDSLDLTTLSIKETHKDDGGQY 16928
Query: 238 TVSAVNEAGVTTCNTRLDVTARPN 261
++ N G T + + +P+
Sbjct: 16929 GITVANVVGQKTASIEIVTLDKPD 16952
Score = 43.9 bits (102), Expect = 2e-04
Identities = 27/106 (25%), Positives = 53/106 (50%), Gaps = 2/106 (1%)
Query: 155 DVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISL 214
+V+AK+ P + V+EG+ + + A+P P + W ++ + V+ +DR+++
Sbjct: 8005 NVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVK-ASDRLTM 8063
Query: 215 YQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARP 260
D+ + K V + DAG YT++ N+ G T + + V P
Sbjct: 8064 KNDHISAHLEVPKSV-RADAGIYTITLENKLGSATASINVKVIGLP 8108
Score = 43.9 bits (102), Expect = 2e-04
Identities = 44/180 (24%), Positives = 77/180 (42%), Gaps = 19/180 (10%)
Query: 137 YACVAKNRAGEATFTVQLD----VLAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQIS 189
+ +A+N AG F+ D + A++ AP P+ K V+ G++ LE I
Sbjct: 18303 FRVIARNAAGN--FSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIR 18360
Query: 190 AIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTT 249
P P + W ++ + ++ R+ + + + TL++KD + D G Y + N G +
Sbjct: 18361 GKPIPDVVWSKDGKELEETAARMEI-KSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKS 18419
Query: 250 CNTRLDVTARPNQTLPAPKQLRVRPTFSK--YLA----LNGKGLNVKQAFNPEGEFQRLA 303
+ V RP P L+V ++ YLA L G N+ + E RL+
Sbjct: 18420 IPITVKVLDRPG---PPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS 18476
Score = 43.1 bits (100), Expect = 3e-04
Identities = 51/200 (25%), Positives = 85/200 (42%), Gaps = 25/200 (12%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P F++ E+ ++ E ++S A +V WY NGR ++ +K + +H L
Sbjct: 6450 PTEFVEHLEDQTVTEFDDAVFSCQLSREKA-NVKWYRNGREIKEGKKYKF-EKDGSIHRL 6507
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL---EGDS 181
I + R D YAC ++R A V + + E R P I + V+ E +
Sbjct: 6508 IIKDCRLDDECEYACGVEDRKSRARLFV--EEIPVEIIRPPQDILEAPGADVVFLAELNK 6565
Query: 182 VKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV-TLLIKDVNKKDAGWYTVS 240
K+E Q W RNN MV D+ + + G++ L I D+ +D G Y
Sbjct: 6566 DKVEVQ----------WLRNN-MVVVQGDKHQMMSE--GKIHRLQICDIKPRDQGEYRFI 6612
Query: 241 AVNEAGVTTCNTRLDVTARP 260
A ++ +L++ A P
Sbjct: 6613 AKDK----EARAKLELAAAP 6628
Score = 43.1 bits (100), Expect = 3e-04
Identities = 32/135 (23%), Positives = 64/135 (47%), Gaps = 6/135 (4%)
Query: 115 IVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK 174
I + KGL ++ + + + +A N AG + V+ KE P + +
Sbjct: 14642 ITTVKGLECVVRNLTEGEEY-TFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQ 14700
Query: 175 KVL---EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNK 231
K++ GD++K+E + P P + WK+ +++++ T R++ T + L I + +
Sbjct: 14701 KLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILK-QTQRVNFETTATSTI-LNINECVR 14758
Query: 232 KDAGWYTVSAVNEAG 246
D+G Y ++A N G
Sbjct: 14759 SDSGPYPLTARNIVG 14773
Score = 42.4 bits (98), Expect = 5e-04
Identities = 29/102 (28%), Positives = 50/102 (49%), Gaps = 10/102 (9%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYL-------NGRTVQSD-DLHKMIVS 117
P I + E M ++EG + K+ G+P P ++W+ N V D ++K++V
Sbjct: 9745 PPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD 9804
Query: 118 EKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
+ +L+ R SD G Y A N G A+ ++L+VL +
Sbjct: 9805 D--TCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGR 9844
Score = 42.0 bits (97), Expect = 7e-04
Identities = 34/128 (26%), Positives = 56/128 (43%), Gaps = 8/128 (6%)
Query: 141 AKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK---KVLEGDSVKLECQISAIPPPKLF 197
A N AGE V E + P K +++ G ++++ ++ P P
Sbjct: 8706 AVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKV 8765
Query: 198 WKRNNEMVQFNTDRISLYQDNTG-RVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
W + E + + DR+ + DN G + L+IKD +KD G Y ++A N G R++V
Sbjct: 8766 WTK--EEGELDKDRVVI--DNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 8821
Query: 257 TARPNQTL 264
P L
Sbjct: 8822 FDVPGPVL 8829
Score = 42.0 bits (97), Expect = 7e-04
Identities = 52/193 (26%), Positives = 78/193 (40%), Gaps = 23/193 (11%)
Query: 93 PAPDVSWYLNGRTVQSDDLHK---MIVSEKGLHSLIFEVVRASDAGAYA--CVAKNRAG- 146
P D L G V+ DL M + + F V + G Y AKN AG
Sbjct: 13925 PKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGA 13984
Query: 147 -----EATFTVQLDVLAKEHKRAPMFIYKPQSKKVLE---GDSVKLEC-QISAIPPPKLF 197
E+T T+ + K+ AP + P K L GD++ L I P PK
Sbjct: 13985 ISAPSESTETI----ICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSS 14040
Query: 198 WKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVT 257
W + + ++ +D + T + L IK +KDAG YT++A N G + ++ V
Sbjct: 14041 WSKAGKDIR-PSDITQITSTPTSSM-LTIKYATRKDAGEYTITATNPFGTKVEHVKVTVL 14098
Query: 258 ARPNQTLPAPKQL 270
P P P ++
Sbjct: 14099 DVPGP--PGPVEI 14109
Score = 42.0 bits (97), Expect = 7e-04
Identities = 28/99 (28%), Positives = 46/99 (46%), Gaps = 2/99 (2%)
Query: 59 IQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSE 118
+ K + P+ ++ + G + SG P P ++W G+ + ++ H ++
Sbjct: 24649 VPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQ-KGQDLIDNNGHYQVIVT 24707
Query: 119 KGLHSLIF-EVVRASDAGAYACVAKNRAGEATFTVQLDV 156
+ SL+F V DAG Y AKNR G TV+LDV
Sbjct: 24708 RSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 24746
Score = 41.2 bits (95), Expect = 0.001
Identities = 28/108 (25%), Positives = 48/108 (44%), Gaps = 2/108 (1%)
Query: 60 QEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEK 119
+E+ PP+ + +PE ++I G+ R++ V G P P W G H +
Sbjct: 12522 KEQLLPPKIL-MPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKAD 12579
Query: 120 GLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMF 167
LI + V D+G Y+ A+N +G T +++ V+ P F
Sbjct: 12580 SSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 12627
Score = 41.2 bits (95), Expect = 0.001
Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 6/102 (5%)
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V G +V L+ + P P + WK++ +++ Q N TL + VN+KD+G
Sbjct: 12935 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNL--CTLELFSVNRKDSG 12992
Query: 236 WYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFS 277
YT++A N +G + +L V +P P +++ +S
Sbjct: 12993 DYTITAENSSGSKSATIKLKVLDKPG----PPASVKINKMYS 13030
Score = 41.2 bits (95), Expect = 0.001
Identities = 39/150 (26%), Positives = 63/150 (42%), Gaps = 17/150 (11%)
Query: 47 STSRGDVNDQDAIQEKFYPPRFIQVP---ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNG 103
S S G + +D + PPR P + + + G ++D + G P P + W + G
Sbjct: 16154 SESTGAITARDEVD----PPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQW-IKG 16208
Query: 104 RTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKR 163
S+ I S SL + D+G Y AKN AGE + TV + VL +
Sbjct: 16209 DQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPG-- 16266
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPP 193
P+ V+ G + + +C ++ PP
Sbjct: 16267 ------PPEGPVVISGVTAE-KCTLAWKPP 16289
Score = 41.2 bits (95), Expect = 0.001
Identities = 21/86 (24%), Positives = 36/86 (41%)
Query: 171 PQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVN 230
P + EG + + C + P P++ W + ++ TL+I DV
Sbjct: 26963 PSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQ 27022
Query: 231 KKDAGWYTVSAVNEAGVTTCNTRLDV 256
K+D G YT+S NE G + + +
Sbjct: 27023 KQDGGLYTLSLGNEFGSDSATVNIHI 27048
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/204 (20%), Positives = 72/204 (35%), Gaps = 37/204 (18%)
Query: 90 SGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAG--- 146
S L A +V+WY +G+ ++ + + S G + L + SD G Y C G
Sbjct: 26370 SVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSK 26429
Query: 147 -------------------------------EATFTVQLDVLAKEH-KRAPMFIYKPQSK 174
E+T T + + A E P+ + Q
Sbjct: 26430 TNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDT 26489
Query: 175 KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDA 234
V K + + P P W ++ + + + L +D G L I + D+
Sbjct: 26490 TVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT-QGGKYKLSEDK-GGFFLEIHKTDTSDS 26547
Query: 235 GWYTVSAVNEAGVTTCNTRLDVTA 258
G YT + N AG + + +L + A
Sbjct: 26548 GLYTCTVKNSAGSVSSSCKLTIKA 26571
Score = 40.4 bits (93), Expect = 0.002
Identities = 30/129 (23%), Positives = 60/129 (46%), Gaps = 7/129 (5%)
Query: 137 YACVAKNRAGEATFTVQLD--VLAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQISAI 191
+ +AKN AG + + + ++ AP + K + G++ +LE +S
Sbjct: 15057 FRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGR 15116
Query: 192 PPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCN 251
PPP + W ++ + ++ T ++ + + L+ KD ++D+G YT++A N G
Sbjct: 15117 PPPTMEWSKDGKELE-GTAKLEIKIADFS-TNLVNKDSTRRDSGAYTLTATNPGGFAKHI 15174
Query: 252 TRLDVTARP 260
+ V RP
Sbjct: 15175 FNVKVLDRP 15183
Score = 40.4 bits (93), Expect = 0.002
Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Query: 152 VQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDR 211
+ + V+AK+ P F + VL G+ +K++ P P + W ++N ++ T R
Sbjct: 15763 LSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLK-QTTR 15821
Query: 212 ISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
++ + L IKD ++D G Y V N AG
Sbjct: 15822 VNA-ESTENNSLLTIKDACREDVGHYVVKLTNSAG 15855
Score = 40.4 bits (93), Expect = 0.002
Identities = 21/86 (24%), Positives = 38/86 (44%), Gaps = 1/86 (1%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 132
++ ++ + K +G P P W +G+ + +K+ +KG L S
Sbjct: 26487 QDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS-EDKGGFFLEIHKTDTS 26545
Query: 133 DAGAYACVAKNRAGEATFTVQLDVLA 158
D+G Y C KN AG + + +L + A
Sbjct: 26546 DSGLYTCTVKNSAGSVSSSCKLTIKA 26571
Score = 40.0 bits (92), Expect = 0.003
Identities = 39/163 (23%), Positives = 66/163 (40%), Gaps = 16/163 (9%)
Query: 97 VSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDV 156
V W+ N + + + M E HS+ F+ + D A + EA TV
Sbjct: 5587 VKWFKNDQRLHTTRSVSM-QDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVL--- 5642
Query: 157 LAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQ 216
+ P F K Q +E D V L+C+IS P ++K E+ + ++ +
Sbjct: 5643 -----EGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEI---KPSKNAVIK 5694
Query: 217 DNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 259
+ + L++K K D G YT + G + +LD+ R
Sbjct: 5695 ADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDIEDR 5733
Score = 40.0 bits (92), Expect = 0.003
Identities = 32/142 (22%), Positives = 62/142 (43%), Gaps = 14/142 (9%)
Query: 122 HSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL---E 178
H F V+ + AG ++ +++ + A++ P P+ K +
Sbjct: 16135 HRYEFRVIARNAAGVFSEPSESTGA---------ITARDEVDPPRISMDPKYKDTIVVHA 16185
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G+S K++ I P P + W + ++ + NT R+ + + +L +KD + D+G Y
Sbjct: 16186 GESFKVDADIYGKPIPTIQWIKGDQELS-NTARLEIKSTDFA-TSLSVKDAVRVDSGNYI 16243
Query: 239 VSAVNEAGVTTCNTRLDVTARP 260
+ A N AG + + V RP
Sbjct: 16244 LKAKNVAGERSVTVNVKVLDRP 16265
Score = 40.0 bits (92), Expect = 0.003
Identities = 30/129 (23%), Positives = 58/129 (44%), Gaps = 7/129 (5%)
Query: 137 YACVAKNRAGEATFTVQLD--VLAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQISAI 191
+ +AKN AG + + AK+ P P+ + + G++ +LE +
Sbjct: 17221 FRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGK 17280
Query: 192 PPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCN 251
P P + W R ++ ++ + R + ++ + L++KD + D G Y + A N AG +
Sbjct: 17281 PLPTIEWLRGDKEIE-ESARCEI-KNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFP 17338
Query: 252 TRLDVTARP 260
+ V RP
Sbjct: 17339 VNVKVLDRP 17347
Score = 40.0 bits (92), Expect = 0.003
Identities = 24/98 (24%), Positives = 41/98 (41%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F ++ N EG+ + +VSG+P P + W +G+ + ++I ++L
Sbjct: 25423 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25482
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKR 163
D G Y A N AG + L V +K+
Sbjct: 25483 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25520
Score = 39.7 bits (91), Expect = 0.004
Identities = 40/158 (25%), Positives = 61/158 (38%), Gaps = 13/158 (8%)
Query: 93 PAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTV 152
P V W + + +Q D K I EK +H L+ R SDAG Y VA A V
Sbjct: 3038 PDITVQWMKDDQELQITDRIK-IQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFV 3096
Query: 153 Q-LDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDR 211
+ DV + K+ I K ++ E + ++ W ++ + F
Sbjct: 3097 EGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAH----------WYKDGIEINFQVQE 3146
Query: 212 ISLYQDNTGRVTLLIKDVNKKDAGWYT-VSAVNEAGVT 248
Y + I + + DAG YT V+ N + VT
Sbjct: 3147 RHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVT 3184
Score = 39.7 bits (91), Expect = 0.004
Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 2/82 (2%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G ++++ ++ P P + W + +++ R+ L QD RV L IK+ + D G Y
Sbjct: 11551 GQTIRILARVKGRPEPDITWTKEGKVL-VREKRVDLIQD-LPRVELQIKEAVRADHGKYI 11608
Query: 239 VSAVNEAGVTTCNTRLDVTARP 260
+SA N +G + ++V RP
Sbjct: 11609 ISAKNSSGHAQGSAIVNVLDRP 11630
Score = 39.7 bits (91), Expect = 0.004
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 1/76 (1%)
Query: 84 RMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKN 143
R+ + G PAP VSW G + D + S +LI + SDAG Y KN
Sbjct: 13629 RLKIPIKGKPAPSVSWK-KGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKN 13687
Query: 144 RAGEATFTVQLDVLAK 159
AG T+ + V+ K
Sbjct: 13688 VAGTKEGTISIKVVGK 13703
Score = 39.7 bits (91), Expect = 0.004
Identities = 21/91 (23%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 69 IQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEV 128
++ E + G ++ +SG PAP + WY + + +Q++ L + + L S++ +
Sbjct: 20504 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNAL-VCVENTTDLASILIKD 20562
Query: 129 VRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
++G Y +N G A+ T+++ +L K
Sbjct: 20563 ADRLNSGCYELKLRNAMGSASATIRVQILDK 20593
Score = 39.7 bits (91), Expect = 0.004
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKD-VNKKDAGWY 237
G S++L +S PPP + W + + + I D T +LLI D VN+ DAG Y
Sbjct: 23089 GASLRLMVSVSGRPPPVITWSKQG--IDLASRAII---DTTESYSLLIVDKVNRYDAGKY 23143
Query: 238 TVSAVNEAGVTTCNTRLDVTARP 260
T+ A N++G + + V P
Sbjct: 23144 TIEAENQSGKKSATVLVKVYDTP 23166
Score = 39.3 bits (90), Expect = 0.005
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 2/85 (2%)
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V G ++L ++ P PK+ W + +M+ RI++ ++ + T+ I D + D G
Sbjct: 7330 VKAGTKIELPATVTGKPEPKITWTKA-DMILKQDKRITI-ENVPKKSTVTIVDSKRSDTG 7387
Query: 236 WYTVSAVNEAGVTTCNTRLDVTARP 260
Y + AVN G T ++V +P
Sbjct: 7388 TYIIEAVNVCGRATAVVEVNVLDKP 7412
Score = 39.3 bits (90), Expect = 0.005
Identities = 36/140 (25%), Positives = 63/140 (45%), Gaps = 12/140 (8%)
Query: 137 YACVAKNRAGEATFT-VQLDVLAKEHKRAPMFIYKP---QSKKVLEGDSVKLECQISAIP 192
+ +A N AGE+ V VL K+ P I + + + GD+++L I +P
Sbjct: 10815 FRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVP 10874
Query: 193 PPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
PK+ WK+ + RI + + L I++ +D G Y+++ N AG T +
Sbjct: 10875 FPKVTWKKEDRDAPTKA-RIDVTPVGS---KLEIRNAAHEDGGIYSLTVENPAGSKTVSV 10930
Query: 253 RLDVTARPNQTLPAPKQLRV 272
++ V +P P+ L V
Sbjct: 10931 KVLVLDKPG----PPRDLEV 10946
Score = 39.3 bits (90), Expect = 0.005
Identities = 37/128 (28%), Positives = 62/128 (48%), Gaps = 14/128 (10%)
Query: 141 AKNRAGEAT-FTVQLDVLAKEHKRAP---MFIYKPQSKKVLEGDSVKLECQISAIPPPKL 196
A+N+AG + + L VL KE P M + + V G ++K++ IS P PK+
Sbjct: 20077 AENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKV 20136
Query: 197 FWKRNN----EMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
R+ ++FNT+ + +N +T+ +K+ DAG Y ++A N +G T
Sbjct: 20137 TLSRDGVPLKATMRFNTE---ITAEN---LTINLKESVTADAGRYEITAANSSGTTKAFI 20190
Query: 253 RLDVTARP 260
+ V RP
Sbjct: 20191 NIVVLDRP 20198
Score = 38.9 bits (89), Expect = 0.006
Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Query: 75 MSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDA 134
+++ G+ R+ +V G P PD++W G+ + + +I + I E VRA D
Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA-DH 11604
Query: 135 GAYACVAKNRAGEATFTVQLDVL 157
G Y AKN +G A + ++VL
Sbjct: 11605 GKYIISAKNSSGHAQGSAIVNVL 11627
Score = 38.9 bits (89), Expect = 0.006
Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
Query: 85 MDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNR 144
+D +SG PAP V+W L ++ D I + K +L + D+G Y +N
Sbjct: 22295 IDVPISGRPAPKVTWKLEEMRLKETD-RVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 22353
Query: 145 AGEATFTVQLDVLAK 159
AG TF+V + V+ +
Sbjct: 22354 AGVKTFSVTVVVIGR 22368
Score = 38.5 bits (88), Expect = 0.008
Identities = 42/153 (27%), Positives = 60/153 (39%), Gaps = 16/153 (10%)
Query: 92 LPAPDV--SWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEAT 149
L PDV W L G+ + + ++I K H LI + G + A N A
Sbjct: 5402 LSEPDVHGQWKLKGQPLTASPDCEIIEDGKK-HILILHNCQLGMTGEVSFQAANAKSAAN 5460
Query: 150 FTVQLDVLAKEHKRAPMFIYKPQSK-KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFN 208
V K P+ P S KV E D K EC++S P + K E+
Sbjct: 5461 LKV---------KELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEIT--G 5509
Query: 209 TDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSA 241
DR L +D T + +++IK +D Y A
Sbjct: 5510 DDRFELIKDGT-KHSMVIKSAAFEDEAKYMFEA 5541
Score = 38.5 bits (88), Expect = 0.008
Identities = 26/138 (18%), Positives = 62/138 (44%), Gaps = 9/138 (6%)
Query: 133 DAGAYACVAKNRAGEATFTVQLD--VLAKEHKRAPMFIYKPQ---SKKVLEGDSVKLECQ 187
D + +A+N G + Q ++ ++ P+ + P+ + G+S++++
Sbjct: 21550 DRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKAL 21609
Query: 188 ISAIPPPKLFWKRNNEMVQFNTDRISL-YQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
+ P P++ W ++ ++ R+++ D G +L ++D + G YTV A N +G
Sbjct: 21610 VQGRPVPRVTWFKDGVEIE---KRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASG 21666
Query: 247 VTTCNTRLDVTARPNQTL 264
++ V P + +
Sbjct: 21667 SAKAEIKVKVQDTPGKVV 21684
Score = 38.5 bits (88), Expect = 0.008
Identities = 21/82 (25%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G + L+ + P PK+ W + ++ + +++SL Q R T +IK ++ D+G YT
Sbjct: 22690 GSDLVLDAAVGGKPEPKIIWTKGDKELDL-CEKVSL-QYTGKRATAVIKFCDRSDSGKYT 22747
Query: 239 VSAVNEAGVTTCNTRLDVTARP 260
++ N +G + + V P
Sbjct: 22748 LTVKNASGTKAVSVMVKVLDSP 22769
Score = 38.5 bits (88), Expect = 0.008
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 132
+ ++I G R+ VSG P P ++W G + S +I + + LI + V
Sbjct: 23082 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLAS---RAIIDTTESYSLLIVDKVNRY 23138
Query: 133 DAGAYACVAKNRAGEATFTVQLDV 156
DAG Y A+N++G+ + TV + V
Sbjct: 23139 DAGKYTIEAENQSGKKSATVLVKV 23162
Score = 38.1 bits (87), Expect = 0.010
Identities = 29/115 (25%), Positives = 42/115 (36%), Gaps = 12/115 (10%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
A + KP+S V EG+S + C P P + W R +++ +T + T
Sbjct: 26188 AARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVL--STSARHQVTTTKYKST 26245
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCN----------TRLDVTARPNQTLPAPK 268
I V D G Y+V N G T VT+ P P P+
Sbjct: 26246 FEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPR 26300
Score = 37.7 bits (86), Expect = 0.013
Identities = 24/69 (34%), Positives = 37/69 (53%), Gaps = 4/69 (5%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLL-IKDVNKKDAGWY 237
G +++L + PPPK+ W + N ++ DRI L +T T L ++VNK DAG Y
Sbjct: 13336 GVTMRLYVPVKGRPPPKITWSKPNVNLR---DRIGLDIKSTDFDTFLRCENVNKYDAGKY 13392
Query: 238 TVSAVNEAG 246
++ N G
Sbjct: 13393 ILTLENSCG 13401
Score = 37.7 bits (86), Expect = 0.013
Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 11/92 (11%)
Query: 157 LAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTD-RI 212
+AKE + P+F + +K L G S + P P + W + + TD R
Sbjct: 19804 IAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPD------TDLRT 19857
Query: 213 SLYQDNT-GRVTLLIKDVNKKDAGWYTVSAVN 243
Y D T R +L I++ N+ D+G YT++ N
Sbjct: 19858 RAYVDTTDSRTSLTIENANRNDSGKYTLTIQN 19889
Score = 37.4 bits (85), Expect = 0.017
Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 3/99 (3%)
Query: 64 YPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ-SDDLHKMIVSEKGLH 122
+ PR + + G+ R V P +V WY NG +Q S +H + G+
Sbjct: 26000 HAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIH--YTNTSGVL 26057
Query: 123 SLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEH 161
+L D+G Y V N GEA+ LDV ++
Sbjct: 26058 TLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDY 26096
Score = 37.0 bits (84), Expect = 0.023
Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
Query: 69 IQVPENM-SIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI-F 126
+++P N SI G +++ V G P P++SW +G ++ ++ V E +++
Sbjct: 17942 LKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTT--RVNVEETATSTVLHI 17999
Query: 127 EVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
+ D G Y A N AG AT + + VL K
Sbjct: 18000 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 18032
Score = 37.0 bits (84), Expect = 0.023
Identities = 28/120 (23%), Positives = 54/120 (45%), Gaps = 8/120 (6%)
Query: 43 VRSRSTSRGDVNDQDAIQEKFYPPRF---IQVPENMSIDEGRFCRMDFKVSGLPAPDVSW 99
V S S G + +D ++ PPR ++ + + + G +++ ++G P P +SW
Sbjct: 19396 VSEPSESTGPIIVKDDVE----PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISW 19451
Query: 100 YLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
+G ++ ++I ++ + + +R D G Y KN AG + V VL K
Sbjct: 19452 AKDGIEIEERARTEIISTDNHTLLTVKDCIR-RDTGQYVLTLKNVAGTRSVAVNCKVLDK 19510
Score = 36.6 bits (83), Expect = 0.030
Identities = 38/139 (27%), Positives = 63/139 (45%), Gaps = 15/139 (10%)
Query: 141 AKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQISAIPPPKLF 197
A N AG V DV E + AP F + ++ L G S+++ I P P++
Sbjct: 14378 AINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVT 14437
Query: 198 WKRNNEMVQFNTDRISLYQDNTGRVTLL-IKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
W ++N ++ +R ++ +NT TLL I + N+ D G + ++ N AG + + V
Sbjct: 14438 WTKDNINLK---NRANI--ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRV 14492
Query: 257 TARPNQTLPAPKQLRVRPT 275
P L +RPT
Sbjct: 14493 LDTPGPV------LNLRPT 14505
Score = 36.6 bits (83), Expect = 0.030
Identities = 30/132 (22%), Positives = 55/132 (41%), Gaps = 5/132 (3%)
Query: 163 RAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV 222
+AP F + ++ V + L C+++ P P + W R + + + + + + G
Sbjct: 24554 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 24613
Query: 223 TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLAL 282
L+I V DA Y V A N+ G + L+V LP + AL
Sbjct: 24614 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLP-----KTLEGMGAVHAL 24668
Query: 283 NGKGLNVKQAFN 294
G+ +++K F+
Sbjct: 24669 RGEVVSIKIPFS 24680
Score = 35.8 bits (81), Expect = 0.051
Identities = 30/120 (25%), Positives = 56/120 (46%), Gaps = 12/120 (10%)
Query: 47 STSRGDVNDQDAIQEKFYPPRFIQV--PENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGR 104
S + G++ D IQE+ P FI + + + G R+ + G P P SW +G+
Sbjct: 9421 SDTTGEIPATD-IQEE--PEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGK 9477
Query: 105 TVQS--DDLHKM-----IVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
++ D +H + + + + +I + S G Y+ AKN+AG+ T ++ V+
Sbjct: 9478 AKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVM 9537
Score = 35.8 bits (81), Expect = 0.051
Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 5/95 (5%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P + + ++I G + + SG P P VSW+ + V DD + + +L
Sbjct: 10446 PTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPA---TL 10502
Query: 125 IFEVVRA--SDAGAYACVAKNRAGEATFTVQLDVL 157
E ++A SD+G Y V +N G Q++V+
Sbjct: 10503 ALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVV 10537
Score = 35.8 bits (81), Expect = 0.051
Identities = 22/84 (26%), Positives = 36/84 (42%), Gaps = 1/84 (1%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 132
+ + I G R+ V G P P V+W+ +G ++ ++ I G SL
Sbjct: 21594 DGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEK-RMNMEITDVLGSTSLFVRDATRD 21652
Query: 133 DAGAYACVAKNRAGEATFTVQLDV 156
G Y AKN +G A +++ V
Sbjct: 21653 HRGVYTVEAKNASGSAKAEIKVKV 21676
Score = 35.4 bits (80), Expect = 0.066
Identities = 24/100 (24%), Positives = 44/100 (44%), Gaps = 10/100 (10%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT------LLIKDVNKK 232
G +++ I P PK W+ + + + D + ++ T ++I + +
Sbjct: 9453 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9512
Query: 233 DAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRV 272
G Y+++A N+AG T N R+ V P PK L+V
Sbjct: 9513 HTGKYSITAKNKAGQKTANCRVKVMDVPG----PPKDLKV 9548
Score = 35.4 bits (80), Expect = 0.066
Identities = 42/166 (25%), Positives = 70/166 (42%), Gaps = 16/166 (9%)
Query: 114 MIVSEKGLHSLIFEVVRASDAGAY--ACVAKNRAGEATFT-VQLDVLAKEHKRAPMFIYK 170
M G++ EV + + Y A N+AG V ++ +E AP
Sbjct: 16514 MCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLD 16573
Query: 171 PQSKKVLE---GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIK 227
+ +K++ G S++L I P P++ W + + + R + D T T L+
Sbjct: 16574 LELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEI-----RDAAIIDVTSSFTSLVL 16628
Query: 228 D-VNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRV 272
D VN+ D+G YT++ N +G + VT R T P L+V
Sbjct: 16629 DNVNRYDSGKYTLTLENSSGTKSA----FVTVRVLDTPSPPVNLKV 16670
Score = 35.4 bits (80), Expect = 0.066
Identities = 25/110 (22%), Positives = 50/110 (45%), Gaps = 2/110 (1%)
Query: 156 VLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLY 215
V+A++ + P + V + +K++ P + W+++ + ++ T R+++
Sbjct: 19014 VIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLK-ETTRVNVS 19072
Query: 216 QDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLP 265
T +L IK+ +K+D G Y + N AG T + V RP P
Sbjct: 19073 SSKTV-TSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGP 19121
Score = 35.4 bits (80), Expect = 0.066
Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 1/85 (1%)
Query: 84 RMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKN 143
++D G P V+W +G+T++ + + S K + SL + D G Y N
Sbjct: 19041 KIDVPFKGRPQATVNWRKDGQTLK-ETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSN 19099
Query: 144 RAGEATFTVQLDVLAKEHKRAPMFI 168
AG T + + VL + P+ I
Sbjct: 19100 SAGSITVPITIIVLDRPGPPGPIRI 19124
Score = 35.4 bits (80), Expect = 0.066
Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP + +S +V G + + + + P ++ W N +Q + +I Y + +G +T
Sbjct: 26001 APRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQ-ESSKIH-YTNTSGVLT 26058
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVT 257
L I D + D+G Y N G + LDVT
Sbjct: 26059 LEILDCHTDDSGTYRAVCTNYKGEASDYATLDVT 26092
Score = 35.0 bits (79), Expect = 0.086
Identities = 26/114 (22%), Positives = 50/114 (43%), Gaps = 8/114 (7%)
Query: 47 STSRGDVNDQDAIQEKFYPPRFIQVP---ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNG 103
S S G + +D ++ PR P + + ++ G R++ V G P P + W
Sbjct: 17236 SDSTGPITAKDEVEL----PRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGD 17291
Query: 104 RTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
+ ++ ++ ++ ++ + +R D G Y A N AG +F V + VL
Sbjct: 17292 KEIEESARCEIKNTDFKALLIVKDAIRI-DGGQYILRASNVAGSKSFPVNVKVL 17344
Score = 34.7 bits (78), Expect = 0.11
Identities = 22/104 (21%), Positives = 44/104 (42%), Gaps = 5/104 (4%)
Query: 56 QDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMI 115
+D + E P F + S+ G+ +++ +SG P P ++W +G ++ +
Sbjct: 16852 KDLVIEPDVKPAF----SSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLK-QTTRINV 16906
Query: 116 VSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
L +L + D G Y N G+ T ++++ L K
Sbjct: 16907 TDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK 16950
Score = 34.3 bits (77), Expect = 0.15
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 3/69 (4%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGL-HSLIFEVVRA 131
+++++ EG ++ KVS V WYLN ++ DD + IV KG L+ A
Sbjct: 2406 KDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIV--KGTKQRLVINRTHA 2463
Query: 132 SDAGAYACV 140
SD G Y +
Sbjct: 2464 SDEGPYKLI 2472
Score = 34.3 bits (77), Expect = 0.15
Identities = 27/126 (21%), Positives = 55/126 (43%), Gaps = 12/126 (9%)
Query: 69 IQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEV 128
++ + + + G R++ VSG P P + W +G+ ++ ++ +++ +L+ +
Sbjct: 15093 VKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKD 15151
Query: 129 VRASDAGAYACVAKNRAGEATFTVQLDVLAKE-HKRAPMFIYKPQSKKVLEGDSVKLECQ 187
D+GAY A N G A + VL + P+ + + S+K C
Sbjct: 15152 STRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEK----------CV 15201
Query: 188 ISAIPP 193
+S PP
Sbjct: 15202 LSWFPP 15207
Score = 34.3 bits (77), Expect = 0.15
Identities = 20/85 (23%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V G+ +K+ I+ P P + W ++ ++ + DN L +KD ++D G
Sbjct: 19429 VKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDN--HTLLTVKDCIRRDTG 19486
Query: 236 WYTVSAVNEAGVTTCNTRLDVTARP 260
Y ++ N AG + V +P
Sbjct: 19487 QYVLTLKNVAGTRSVAVNCKVLDKP 19511
Score = 33.9 bits (76), Expect = 0.19
Identities = 39/137 (28%), Positives = 60/137 (43%), Gaps = 11/137 (8%)
Query: 178 EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD-AGW 236
EGD V L I+ ++ W N++V + L NT TL+I VN +D G
Sbjct: 4381 EGDIVHLTTSITNAK--EVNWYFENKLVPSDEKFKCLQDQNT--YTLVIDKVNTEDHQGE 4436
Query: 237 YTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGLNVKQAFNPE 296
Y A+N++G T + +L V R P K+ ++ P L ++ A P
Sbjct: 4437 YVCEALNDSGKTATSAKLTVVKR---AAPVIKR-KIEPLEVALGHLAKFTCEIQSA--PN 4490
Query: 297 GEFQRLAAQSGLYESEE 313
FQ A +YES++
Sbjct: 4491 VRFQWFKAGREIYESDK 4507
Score = 33.9 bits (76), Expect = 0.19
Identities = 22/94 (23%), Positives = 37/94 (39%), Gaps = 4/94 (4%)
Query: 172 QSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNK 231
Q+ V G S++L P P W + + + D TL +++ N+
Sbjct: 21993 QTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRAD----IHTTDSFSTLTVENCNR 22048
Query: 232 KDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLP 265
DAG YT++ N +G + + V P P
Sbjct: 22049 NDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGP 22082
Score = 33.5 bits (75), Expect = 0.25
Identities = 36/159 (22%), Positives = 62/159 (38%), Gaps = 16/159 (10%)
Query: 14 VFQAQDDSGAQDSQQHNSEHARLQVP------TSQVRSRSTSRGDVNDQDAIQEKFYPPR 67
V +A D+ + + N + R +V Q R + ++ +D + +K YP
Sbjct: 13255 VKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKD 13314
Query: 68 FIQVPEN---------MSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSE 118
+ PE + + G R+ V G P P ++W ++ D + I S
Sbjct: 13315 ILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLR-DRIGLDIKST 13373
Query: 119 KGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
L E V DAG Y +N G+ +T+ + VL
Sbjct: 13374 DFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVL 13412
Score = 33.1 bits (74), Expect = 0.33
Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V G +V+ I +P P W + ++ + + ++ DN V L IK+ ++D G
Sbjct: 11150 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTD-EHYTVETDNFSSV-LTIKNCLRRDTG 11207
Query: 236 WYTVSAVNEAGVTTCNTRLDVTARP 260
Y ++ N AG T L V P
Sbjct: 11208 EYQITVSNAAGSKTVAVHLTVLDVP 11232
Score = 33.1 bits (74), Expect = 0.33
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 1/95 (1%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP F + ++ G ++D G P P V+W+ + ++ +E
Sbjct: 15775 PPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLT 15834
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
I + R D G Y N AGEA T+ + VL K
Sbjct: 15835 IKDACR-EDVGHYVVKLTNSAGEAIETLNVIVLDK 15868
Score = 32.7 bits (73), Expect = 0.43
Identities = 26/104 (25%), Positives = 44/104 (42%), Gaps = 6/104 (5%)
Query: 59 IQEKFYPPRFI---QVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMI 115
++++ PP I + I G R+ + G+P P V+W R + ++
Sbjct: 10837 VKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTK--ARID 10894
Query: 116 VSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
V+ G L D G Y+ +N AG T +V++ VL K
Sbjct: 10895 VTPVG-SKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDK 10937
Score = 32.7 bits (73), Expect = 0.43
Identities = 22/95 (23%), Positives = 38/95 (40%), Gaps = 7/95 (7%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P + I VP GR + ++G P P SW+ G ++ + + + + L
Sbjct: 23372 PQKTIHVPA------GRPVELVIPIAGRPPPAASWFFAGSKLRESE-RVTVETHTKVAKL 23424
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
D G Y KN G + T+++ +L K
Sbjct: 23425 TIRETTIRDTGEYTLELKNVTGTTSETIKVIILDK 23459
Score = 32.0 bits (71), Expect = 0.73
Identities = 30/134 (22%), Positives = 44/134 (32%), Gaps = 9/134 (6%)
Query: 32 EHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYPP----RFIQVPENMSIDEGRFCRMDF 87
EH + V S + IQ+ PP R + + + G +
Sbjct: 8989 EHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPA 9048
Query: 88 KVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS-----LIFEVVRASDAGAYACVAK 142
V+GLP P + W N ++ I E+ S L D G Y A
Sbjct: 9049 DVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTAS 9108
Query: 143 NRAGEATFTVQLDV 156
NR G V ++V
Sbjct: 9109 NRLGSVFRNVHVEV 9122
Score = 32.0 bits (71), Expect = 0.73
Identities = 33/126 (26%), Positives = 58/126 (46%), Gaps = 8/126 (6%)
Query: 181 SVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIK-DVNKKDAGWYTV 239
+++L I P P++ W R++ + D+ S+ ++T TLLI +VN+ D+G Y +
Sbjct: 15505 TLRLFVPIKGRPAPEVKWARDHGE---SLDKASI--ESTSSYTLLIVGNVNRFDSGKYIL 15559
Query: 240 SAVNEAGVTTC--NTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGLNVKQAFNPEG 297
+ N +G + N R+ T P Q L + + T + L G +K +
Sbjct: 15560 TVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKR 15619
Query: 298 EFQRLA 303
E R A
Sbjct: 15620 ESTRKA 15625
Score = 31.6 bits (70), Expect = 0.96
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 89 VSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEA 148
+ G P P SW G+ ++ D+ I S L + DAG Y A N G
Sbjct: 14031 ILGKPLPKSSWSKAGKDIRPSDI-TQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTK 14089
Query: 149 TFTVQLDVLAKEHKRAPMFIYKPQSKK 175
V++ VL P+ I ++K
Sbjct: 14090 VEHVKVTVLDVPGPPGPVEISNVSAEK 14116
Score = 31.6 bits (70), Expect = 0.96
Identities = 26/109 (23%), Positives = 46/109 (42%), Gaps = 6/109 (5%)
Query: 52 DVNDQDAIQEKFYPPRF---IQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQS 108
DV ++EK P +++ + ++I G R+ + G P P+V W G+
Sbjct: 16554 DVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKW---GKVDGE 16610
Query: 109 DDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
+I SL+ + V D+G Y +N +G + V + VL
Sbjct: 16611 IRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVL 16659
Score = 31.6 bits (70), Expect = 0.96
Identities = 20/82 (24%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G V+L I+ PPP W ++ ++R+++ + +T L I++ +D G YT
Sbjct: 23381 GRPVELVIPIAGRPPPAASWFFAGSKLR-ESERVTV-ETHTKVAKLTIRETTIRDTGEYT 23438
Query: 239 VSAVNEAGVTTCNTRLDVTARP 260
+ N G T+ ++ + +P
Sbjct: 23439 LELKNVTGTTSETIKVIILDKP 23460
Score = 30.8 bits (68), Expect = 1.6
Identities = 23/87 (26%), Positives = 37/87 (42%), Gaps = 14/87 (16%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT-----LLIKDVNKKD 233
G +++ +S PPP + W N +L Q+ T T ++IK+ +
Sbjct: 10167 GGVIRIIAYVSGKPPPTVTWNMNER---------TLPQEATIETTAISSSMVIKNCQRSH 10217
Query: 234 AGWYTVSAVNEAGVTTCNTRLDVTARP 260
G Y++ A NEAG +DV P
Sbjct: 10218 QGVYSLLAKNEAGERKKTIIVDVLDVP 10244
Score = 30.4 bits (67), Expect = 2.1
Identities = 24/105 (22%), Positives = 43/105 (40%), Gaps = 13/105 (12%)
Query: 90 SGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEAT 149
+G P P +W + +++ D KM + L+ SD G Y +NR +
Sbjct: 7047 TGYPRPTATWCFGDKVLETGDRVKM-KTLSAYAELVISPSERSDKGIYTLKLENRVKTIS 7105
Query: 150 FTVQLDVLAKEHKRAPMFIYKPQSKKVLE-GDSVKLECQISAIPP 193
+ ++V+A +P + K L+ GD K ++ PP
Sbjct: 7106 GEIDVNVIA-----------RPSAPKELKFGDITKDSVHLTWEPP 7139
Score = 30.4 bits (67), Expect = 2.1
Identities = 25/113 (22%), Positives = 45/113 (39%), Gaps = 5/113 (4%)
Query: 47 STSRGDVNDQDAIQ--EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGR 104
S S G + +D I P++ V + + G ++ + G P PDV W +G+
Sbjct: 18318 SDSSGAITARDEIDAPNASLDPKYKDV---IVVHAGETFVLEADIRGKPIPDVVWSKDGK 18374
Query: 105 TVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
++ I S +L+ + +D G Y N G + + + VL
Sbjct: 18375 ELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVL 18427
Score = 30.0 bits (66), Expect = 2.8
Identities = 25/96 (26%), Positives = 48/96 (50%), Gaps = 7/96 (7%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLL-IKDVNKKDAGWY 237
G+ V++ PPP + W+++ + + + R S+ +NT +LL I V + D G Y
Sbjct: 20914 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSDA-RYSI--ENTDSSSLLTIPQVTRNDTGKY 20970
Query: 238 TVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVR 273
++ N G +T V+ + T A ++L+V+
Sbjct: 20971 ILTIENGVGEPKSST---VSVKVLDTPAACQKLQVK 21003
Score = 30.0 bits (66), Expect = 2.8
Identities = 16/61 (26%), Positives = 26/61 (42%), Gaps = 2/61 (3%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G +V LE P P + W ++ + + ++TL IK+ K+ G YT
Sbjct: 21206 GHNVHLELPYKGKPKPSISWLKDG--LPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT 21263
Query: 239 V 239
V
Sbjct: 21264 V 21264
Score = 29.6 bits (65), Expect = 3.6
Identities = 24/102 (23%), Positives = 42/102 (41%), Gaps = 8/102 (7%)
Query: 60 QEKFYPPRFIQVPENMSIDEGRFC---RMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIV 116
+++ PP + + R C R+ + G PAP+V W + + L K +
Sbjct: 15480 EDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARD----HGESLDKASI 15535
Query: 117 SEKGLHS-LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
++ LI V D+G Y +N +G + V + VL
Sbjct: 15536 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVL 15577
Score = 29.6 bits (65), Expect = 3.6
Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 3/84 (3%)
Query: 75 MSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL-IFEVVRASD 133
++I G +D V G P P + W + + D K+ + G + + + SD
Sbjct: 22685 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKEL--DLCEKVSLQYTGKRATAVIKFCDRSD 22742
Query: 134 AGAYACVAKNRAGEATFTVQLDVL 157
+G Y KN +G +V + VL
Sbjct: 22743 SGKYTLTVKNASGTKAVSVMVKVL 22766
Score = 29.3 bits (64), Expect = 4.7
Identities = 18/86 (20%), Positives = 37/86 (43%), Gaps = 4/86 (4%)
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V +G ++L I P P W + + + + ++ + L+IK+ ++ D+G
Sbjct: 23776 VRQGGVIRLTIPIKGKPFPICKWTKEGQDIS----KRAMIATSETHTELVIKEADRGDSG 23831
Query: 236 WYTVSAVNEAGVTTCNTRLDVTARPN 261
Y + N+ G ++ V PN
Sbjct: 23832 TYDLVLENKCGKKAVYIKVRVIGSPN 23857
Score = 28.9 bits (63), Expect = 6.2
Identities = 33/112 (29%), Positives = 44/112 (39%), Gaps = 26/112 (23%)
Query: 89 VSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI----FEVVRAS---DAGAYACVA 141
V G PAP V+W R V D+ V KG L+ F V+ S D+G Y+
Sbjct: 12258 VRGRPAPKVTW----RKVGIDN-----VVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTL 12308
Query: 142 KNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPP 193
N AGE V + VL + + + D K C +S PP
Sbjct: 12309 VNPAGEKAVFVNVRVLDTPGPVSDLKV----------SDVTKTSCHVSWAPP 12350
Score = 28.5 bits (62), Expect = 8.1
Identities = 26/125 (20%), Positives = 48/125 (38%), Gaps = 6/125 (4%)
Query: 35 RLQVPTSQVRSRSTSRGDVNDQDAIQ--EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGL 92
RLQ+ + R + R D++A E P+ +++ +D G+ M
Sbjct: 6595 RLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAY 6654
Query: 93 PAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTV 152
P + W+ + + K I + S + D G Y V +N+ G+A +
Sbjct: 6655 PKAEAEWFKENEPLST----KTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFI 6710
Query: 153 QLDVL 157
L V+
Sbjct: 6711 NLKVI 6715
Score = 28.5 bits (62), Expect = 8.1
Identities = 19/73 (26%), Positives = 31/73 (42%), Gaps = 1/73 (1%)
Query: 84 RMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKN 143
+++ V G P P V+W + ++ + I E VR SD+G Y A+N
Sbjct: 14712 KVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVR-SDSGPYPLTARN 14770
Query: 144 RAGEATFTVQLDV 156
GE + + V
Sbjct: 14771 IVGEVGDVITIQV 14783
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 127 bits (320), Expect = 1e-29
Identities = 66/216 (30%), Positives = 115/216 (53%)
Query: 61 EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKG 120
E+ Y P F+ P + EG+ R D KV G P P+ W+ +G+ + +D HK+++ E G
Sbjct: 1406 ERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDG 1465
Query: 121 LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGD 180
SLI SD+G + VA+NRAG ++ +V L V A EH+ PMF+ K ++ + EG
Sbjct: 1466 TQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGS 1525
Query: 181 SVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVS 240
++++ + + P P + W +N++++ + + G L I +D+ WYT +
Sbjct: 1526 RLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTAT 1585
Query: 241 AVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTF 276
A+N+AG T +++V + P K + R T+
Sbjct: 1586 AINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTY 1621
Score = 95.9 bits (237), Expect = 4e-20
Identities = 62/198 (31%), Positives = 92/198 (46%), Gaps = 7/198 (3%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIV--SEKGLH 122
PP F N + G R ++ P P V+WY +G+ ++ D K S+KGL+
Sbjct: 25192 PPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLY 25251
Query: 123 SLIFEVVRASDAGAYACVAKNRAGE----ATFTVQLDVLAKEHKRAPMFIYKPQSKKVLE 178
L V D Y VA+N+ GE A TV L + PMF + + E
Sbjct: 25252 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQE 25311
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G SV E ++S IPPP L W+++ + + + I + + L I+D +D G+Y
Sbjct: 25312 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPN-IEIIHEGLDYYALHIRDTLPEDTGYYR 25370
Query: 239 VSAVNEAGVTTCNTRLDV 256
V+A N AG T+C L V
Sbjct: 25371 VTATNTAGSTSCQAHLQV 25388
Score = 92.8 bits (229), Expect = 3e-19
Identities = 62/213 (29%), Positives = 109/213 (51%), Gaps = 13/213 (6%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVS-EKGLHSL 124
P F Q +++ + EG + +SG P P+VSW+ +G+ + + L + +S G L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
V +++G Y+ A N +G+AT T +L L K P F+ + QS V +G V+L
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAEL--LVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTD-RISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
+ +++ IP P + + R+ +Q + D +IS D +LLI + +D+G Y+V+A N
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGD---LYSLLIAEAYPEDSGTYSVNATN 180
Query: 244 EAGVTTCNTRL------DVTARPNQTLPAPKQL 270
G T L +V A+ +T+ + Q+
Sbjct: 181 SVGRATSTAELLVQGEEEVPAKKTKTIVSTAQI 213
Score = 84.7 bits (208), Expect = 1e-16
Identities = 60/231 (25%), Positives = 94/231 (40%), Gaps = 42/231 (18%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP + +N+++ EG ++ +SG P+P V+WY ++S + I + G+ L
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESS-IDFQITFQSGIARL 954
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDV----------------LAKEHKR----- 163
+ A D+G + C A N AG + + L V E KR
Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014
Query: 164 --------------------APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNE 203
AP FI KP +K++EG SV CQ+ P P ++WK++
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1074
Query: 204 MVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRL 254
+ Y TG L+I DAG YT+ N+ G T+ + L
Sbjct: 1075 PLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 78.6 bits (192), Expect = 7e-15
Identities = 55/182 (30%), Positives = 94/182 (51%), Gaps = 6/182 (3%)
Query: 75 MSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDA 134
MSI+EG+ R+ K + A DV W LNG + + + ++ VS +L + D
Sbjct: 26551 MSINEGQ--RLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSD-QTLTIKQASHRDE 26607
Query: 135 GAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPP 194
G C++K + G L L+KE AP FI +P+S+ + EG +V C+IS P P
Sbjct: 26608 GILTCISKTKEGIVKCQYDL-TLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSP 26666
Query: 195 KLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRL 254
++ W +NN + +++ +S+ + + +L I++ + D+G YT+ A N G + L
Sbjct: 26667 EIEWFKNNLPISISSN-VSISR-SRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASL 26724
Query: 255 DV 256
V
Sbjct: 26725 MV 26726
Score = 77.8 bits (190), Expect = 1e-14
Identities = 53/197 (26%), Positives = 83/197 (42%), Gaps = 2/197 (1%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKG-LHSL 124
P F + N+++ + KV+G P P V WY G+ + +D L I KG H L
Sbjct: 24431 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24490
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
I V DA Y A N+ G + T L+V P + + L G+ V +
Sbjct: 24491 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSI 24550
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
+ S P P + W++ +++ N + + + V +KDAG+Y V A N
Sbjct: 24551 KIPFSGKPDPVITWQKGQDLID-NNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNR 24609
Query: 245 AGVTTCNTRLDVTARPN 261
G+ LDV P+
Sbjct: 24610 FGIDQKTVELDVADVPD 24626
Score = 69.3 bits (168), Expect = 4e-12
Identities = 53/229 (23%), Positives = 88/229 (38%), Gaps = 22/229 (9%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P FI+ N I G + V G+P P + W+ NG + +K + HSLI
Sbjct: 3457 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDD-HSLI 3515
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK--EHKRA------------------P 165
+ D G Y C+A N G+ + L + +K HK P
Sbjct: 3516 ILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPP 3575
Query: 166 MFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLL 225
F+ + + + +G E + P P + W + N+ + + ++ N G T +
Sbjct: 3576 HFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPN-GSGTFI 3634
Query: 226 IKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRP 274
+ D ++D+G Y A N G +TC L V P + + P
Sbjct: 3635 VNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTP 3683
Score = 65.5 bits (158), Expect = 6e-11
Identities = 60/254 (23%), Positives = 116/254 (45%), Gaps = 21/254 (8%)
Query: 7 GPQNAAAVFQAQDDS--GAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFY 64
G +A + QD+S +++ ++ +SE +V T +++ + G + +D
Sbjct: 4192 GVASAVVSDEKQDESLKPSEEKEESSSESGTEEVATVKIQE---AEGGLIKEDG------ 4242
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P + + +S +EG + ++ A +V+WY + V SD+ K + ++ ++L
Sbjct: 4243 PMIHTPLVDTVS-EEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCL-QDQNTYTL 4298
Query: 125 IFEVVRASD-AGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
+ + V D G Y C A N +G+ + +L V+ + AP+ K + +V G K
Sbjct: 4299 VIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVV---KRAAPVIKRKIEPLEVALGHLAK 4355
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
C+I + P + W + + + +D+ S+ + + +L I D G YT A N
Sbjct: 4356 FTCEIQSAPNVRFQWFKAGREI-YESDKCSI-RSSKYISSLEILRTQVVDCGEYTCKASN 4413
Query: 244 EAGVTTCNTRLDVT 257
E G +C L VT
Sbjct: 4414 EYGSVSCTATLTVT 4427
Score = 64.3 bits (155), Expect = 1e-10
Identities = 39/126 (30%), Positives = 64/126 (50%), Gaps = 1/126 (0%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP F+Q ++M++ +G R+ +V+G+P P V +Y +G +QS L I E L+SL
Sbjct: 103 PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQS-SLDFQISQEGDLYSL 161
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
+ D+G Y+ A N G AT T +L V +E A + ++ E ++
Sbjct: 162 LIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRI 221
Query: 185 ECQISA 190
E +I A
Sbjct: 222 EKKIEA 227
Score = 64.3 bits (155), Expect = 1e-10
Identities = 57/260 (21%), Positives = 110/260 (42%), Gaps = 16/260 (6%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP+ +Q + +++ G+ R +SG P P +SWY + + + K + + L
Sbjct: 3192 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3251
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE--HKRAPMFIYKP------QSKKV 176
+ E DA Y C AKN G AT + L V E M +Y P Q
Sbjct: 3252 LIEAF-PEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVT 3310
Query: 177 LEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGW 236
EG + +C++S ++ ++ ++ R++ ++D L I + +D G
Sbjct: 3311 SEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDT---YQLEIAEAYPEDEGT 3367
Query: 237 YTVSAVNEAGVTTCNTRLDVTARP---NQTLPAPKQLRVRPTFSKYLALNGKGL-NVKQA 292
YT A N G + L + A ++ + ++ ++ S +L+ +GL + +
Sbjct: 3368 YTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQ 3427
Query: 293 FNPEGEFQRLAAQSGLYESE 312
+ E L ++S +Y ++
Sbjct: 3428 LSKINETLELLSESPVYPTK 3447
Score = 62.0 bits (149), Expect = 7e-10
Identities = 52/176 (29%), Positives = 78/176 (44%), Gaps = 16/176 (9%)
Query: 96 DVSWYLNGRTV--QSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQ 153
D WY +G + Q + HK +V E+ +H + R SDAG Y V AG +V
Sbjct: 3130 DAHWYKDGIEINFQVQERHKYVV-ERRIHRMFISETRQSDAGEYTFV----AGRNRSSVT 3184
Query: 154 LDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRIS 213
L V A E P + + Q V G + IS P PK+ W + +++ +T
Sbjct: 3185 LYVNAPE---PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKC 3239
Query: 214 LYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV----TARPNQTLP 265
+ + TLL+ + +DA YT A N+ GV T + L V P+Q +P
Sbjct: 3240 KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMP 3295
Score = 61.6 bits (148), Expect = 9e-10
Identities = 50/209 (23%), Positives = 84/209 (40%), Gaps = 30/209 (14%)
Query: 97 VSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDV 156
V+WY R +++ + ++ I E G+ L + + D G Y C N GE + +L V
Sbjct: 25103 VTWYFGVRQLENSEKYE-ITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25161
Query: 157 LAKEH-----------------------KRAPMFIYKPQSKKVLEGDSVKLECQISAIPP 193
+R P F +K G++V+ I+ P
Sbjct: 25162 KGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPE 25221
Query: 194 PKLFWKRNNEMVQ-FNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
P + W ++ + ++ + D+ ++ + G L I V D YTV A N+ G +C
Sbjct: 25222 PHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKA 25281
Query: 253 RLDVTARPNQTLPAPKQLRVRPTFSKYLA 281
+L VT P P +RP F + LA
Sbjct: 25282 KLTVTLH-----PPPTDSTLRPMFKRLLA 25305
Score = 60.8 bits (146), Expect = 1e-09
Identities = 47/185 (25%), Positives = 87/185 (47%), Gaps = 8/185 (4%)
Query: 80 GRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYAC 139
G ++ ++ G P PD+ WY G+ + +KM S+ H+L D G Y C
Sbjct: 24050 GEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKM-SSDGRTHTLTVMTEEQEDEGVYTC 24108
Query: 140 VAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWK 199
+A N GE + +L +L + P + K + + G +++L P P + W
Sbjct: 24109 IATNEVGEVETSSKL-LLQATPQFHPGYPLKEKYYGAV-GSTLRLHVMYIGRPVPAMTWF 24166
Query: 200 RNNEMVQFNTDRISLYQDNTGRVT-LLIKDVNKK-DAGWYTVSAVNEAGVTTCNTRLDVT 257
+++Q N++ I++ +NT T L++K+V +K AG Y V N G +++
Sbjct: 24167 HGQKLLQ-NSENITI--ENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQ 24223
Query: 258 ARPNQ 262
+P++
Sbjct: 24224 DKPDK 24228
Score = 60.1 bits (144), Expect = 3e-09
Identities = 36/117 (30%), Positives = 59/117 (50%), Gaps = 2/117 (1%)
Query: 140 VAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWK 199
V R + T T ++ + P + ++ V+EG+SV LEC IS P P + W
Sbjct: 872 VLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWY 931
Query: 200 RNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
R + ++ + D +Q R L+I++ +D+G +T SAVNEAG + + L V
Sbjct: 932 REDYQIESSIDFQITFQSGIAR--LMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 59.7 bits (143), Expect = 3e-09
Identities = 62/264 (23%), Positives = 108/264 (40%), Gaps = 44/264 (16%)
Query: 51 GDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD 110
GD+ D++ Q+ F+ + + CR+ G P V W +G+ +++ +
Sbjct: 1646 GDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLT--PIGDPTMVVEWLHDGKPLEAAN 1703
Query: 111 LHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAG----EATFTV-------------- 152
+MI +E G SL + V + D+G C A N+ G AT V
Sbjct: 1704 RLRMI-NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPE 1762
Query: 153 ---------QLDVLAKE-----------HKRAPMFIYKPQSKKVLEGDSVKLECQISAIP 192
+L+ +A E K+ P + P+ +VLEG++ + C+++ P
Sbjct: 1763 GRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYP 1822
Query: 193 PPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
PK+ W N ++++ + R + D G L I D D G V+A N GV
Sbjct: 1823 QPKVNWYLNGQLIR-KSKRFRVRYD--GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKV 1879
Query: 253 RLDVTARPNQTLPAPKQLRVRPTF 276
+L++ R + + RP F
Sbjct: 1880 KLEIQQREDFRSVLRRAPEPRPEF 1903
Score = 58.2 bits (139), Expect = 1e-08
Identities = 46/166 (27%), Positives = 79/166 (47%), Gaps = 13/166 (7%)
Query: 74 NMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASD 133
N+ + E ++ +VS P +V WY + ++ I++E L+ + D
Sbjct: 5974 NIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYE-ILTEGRKRILVIQNAHLED 6031
Query: 134 AGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPP 193
AG Y C + + D K H+ A FI KPQ+ ++LEG+ + C IS
Sbjct: 6032 AGNYNCRLPSS--------RTDGKVKVHELAAEFISKPQNLEILEGEKAEFVCSISKESF 6083
Query: 194 PKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTV 239
P + WKR+++ ++ + D+ + D RV L++KD +D G Y V
Sbjct: 6084 P-VQWKRDDKTLE-SGDKYDVIADGKKRV-LVVKDATLQDMGTYVV 6126
Score = 55.5 bits (132), Expect = 6e-08
Identities = 34/125 (27%), Positives = 58/125 (46%), Gaps = 1/125 (0%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P FI P + +I+EG+ ++SG P+P++ W+ N + S + I + ++SL
Sbjct: 26637 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPI-SISSNVSISRSRNVYSLE 26695
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLE 185
SD+G Y AKN G+ + T L VL + + + + L+G
Sbjct: 26696 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQS 26755
Query: 186 CQISA 190
Q+SA
Sbjct: 26756 VQMSA 26760
Score = 54.3 bits (129), Expect = 1e-07
Identities = 35/102 (34%), Positives = 50/102 (49%), Gaps = 3/102 (2%)
Query: 163 RAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV 222
+AP F QS VLEG + E IS P P++ W R+ +++ +T + GR
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 223 TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV---TARPN 261
L I V K ++G Y++ A N +G T L V TA PN
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPN 105
Score = 54.3 bits (129), Expect = 1e-07
Identities = 33/129 (25%), Positives = 63/129 (48%), Gaps = 8/129 (6%)
Query: 141 AKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK----KVLEGDSVKLECQISAIPPPKL 196
A N GE+ ++ L+V+ ++ + P + + KV G+ V + ++ +P PK+
Sbjct: 8874 AVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKI 8933
Query: 197 FWKRNNEMVQFNTDRISLYQDNTGR----VTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
W +N +++ TD + + ++ R L I ++D G YTV+A N G N
Sbjct: 8934 EWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNV 8993
Query: 253 RLDVTARPN 261
++V RP+
Sbjct: 8994 HVEVYDRPS 9002
Score = 53.5 bits (127), Expect = 2e-07
Identities = 38/158 (24%), Positives = 66/158 (41%), Gaps = 4/158 (2%)
Query: 7 GPQNAAAVFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYPP 66
G + +A +D+ + Q LQ + R G + Q++ P
Sbjct: 1738 GTDHTSATLIVKDEKSLVEESQLPEGRKGLQ--RIEELERMAHEGALTGVTTDQKEKQKP 1795
Query: 67 RFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIF 126
+ PE + + EG R +V+G P P V+WYLNG+ ++ + V G+H L
Sbjct: 1796 DIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKS--KRFRVRYDGIHYLDI 1853
Query: 127 EVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRA 164
++ D G A+N G V+L++ +E R+
Sbjct: 1854 VDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRS 1891
Score = 53.1 bits (126), Expect = 3e-07
Identities = 43/153 (28%), Positives = 68/153 (44%), Gaps = 11/153 (7%)
Query: 117 SEKGLHSLIFEVVRASDAGAYACVAK--NRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK 174
+++ + L F V + G Y K N AG + + + + P I +
Sbjct: 9570 NKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFM 9629
Query: 175 KVLEGDSVKLECQISAIPPPKLFWKR-------NNEMVQFNTDRISLYQDNTGRVTLLIK 227
+V EG +V + +I +P P L W + N E V ++T L D+T TL+I
Sbjct: 9630 EVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDT--CTLVIP 9687
Query: 228 DVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARP 260
+ D G YT++AVN G + RL+V RP
Sbjct: 9688 QSRRSDTGLYTITAVNNLGTASKEMRLNVLGRP 9720
Score = 52.8 bits (125), Expect = 4e-07
Identities = 48/162 (29%), Positives = 72/162 (44%), Gaps = 11/162 (6%)
Query: 93 PAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTV 152
P V WY +G V D ++M S++ +H L + SDA Y+CV T T
Sbjct: 2155 PFVKVKWYKDGMEVHEGDKYRMH-SDRKVHFLSILTIDTSDAEDYSCVLVEDENVKT-TA 2212
Query: 153 QLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRI 212
+L V F+ + Q +V E S +LEC +S P + K + V+ ++
Sbjct: 2213 KLIV----EGAVVEFVKELQDIEVPESYSGELECIVS---PENIEGKWYHNDVELKSNGK 2265
Query: 213 SLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRL 254
GR L +KDV K+D G Y S V + TTC ++
Sbjct: 2266 YTITSRRGRQNLTVKDVTKEDQGEY--SFVIDGKKTTCKLKM 2305
Score = 52.8 bits (125), Expect = 4e-07
Identities = 40/147 (27%), Positives = 71/147 (48%), Gaps = 3/147 (2%)
Query: 115 IVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQ-LDVLAKEHKRAPMFIYKPQS 173
IV+E + + + + + + A N G++ V + V+AK+ P +
Sbjct: 17764 IVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNT 17823
Query: 174 KKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD 233
+ G+ +K+E + P P + W ++ E ++ T R+++ + T V L IK+ NK D
Sbjct: 17824 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLK-QTTRVNVEETATSTV-LHIKEGNKDD 17881
Query: 234 AGWYTVSAVNEAGVTTCNTRLDVTARP 260
G YTV+A N AG T N + V +P
Sbjct: 17882 FGKYTVTATNSAGTATENLSVIVLEKP 17908
Score = 52.4 bits (124), Expect = 5e-07
Identities = 32/143 (22%), Positives = 67/143 (46%), Gaps = 2/143 (1%)
Query: 123 SLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSV 182
SL+ ++ + A+N G + V + + P I P+ + G +
Sbjct: 12360 SLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKL 12419
Query: 183 KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAV 242
++E + P P WK+ + V + +++++ ++ + L+IKDV +KD+G+Y+++A
Sbjct: 12420 RIEAHVYGKPHPTCKWKKGEDEV-VTSSHLAVHKADSSSI-LIIKDVTRKDSGYYSLTAE 12477
Query: 243 NEAGVTTCNTRLDVTARPNQTLP 265
N +G T ++ V P P
Sbjct: 12478 NSSGTDTQKIKVVVMDAPGPPQP 12500
Score = 51.6 bits (122), Expect = 9e-07
Identities = 33/153 (21%), Positives = 65/153 (42%), Gaps = 6/153 (3%)
Query: 14 VFQAQDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFY------PPR 67
+F +D G N + ++ S+ D + A+ + PP
Sbjct: 3517 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 3576
Query: 68 FIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFE 127
F++ + + +G ++ V G PAP V+W+ + + + + +I + G + I
Sbjct: 3577 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 3636
Query: 128 VVRASDAGAYACVAKNRAGEATFTVQLDVLAKE 160
+ D+G Y C A+N GE+T +L VL ++
Sbjct: 3637 DPQREDSGLYICKAENMLGESTCAAELLVLLED 3669
Score = 51.2 bits (121), Expect = 1e-06
Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKM-IVSEKGLHS 123
PP+ +P ++SIDEG+ + +G P P+V+W GR + S + + I + L +
Sbjct: 26831 PPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTT 26890
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDV 156
LI V+ D G Y N G + TV + +
Sbjct: 26891 LIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923
Score = 50.4 bits (119), Expect = 2e-06
Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 5/117 (4%)
Query: 52 DVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDL 111
D+++ +A++ F R +N I EG K+SG P P ++WY +G+ ++ +
Sbjct: 1236 DISESEAVESGF-DSRI----KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGER 1290
Query: 112 HKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFI 168
++M + G SL VV D G Y A N G A + +L V AP +I
Sbjct: 1291 YQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYI 1347
Score = 50.1 bits (118), Expect = 3e-06
Identities = 48/189 (25%), Positives = 83/189 (43%), Gaps = 14/189 (7%)
Query: 60 QEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVS---WYLNGRTVQSDDLHKMIV 116
Q K P +F++ +++ + E F L +P + W +G ++ H+ I
Sbjct: 4612 QLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIA 4671
Query: 117 SEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKK- 175
K I +V + SDAG Y CV + E T T +L V + P+ K ++
Sbjct: 4672 DGKDRKLHIIDV-QLSDAGEYTCVLRLGNKEKTSTAKLVV-----EELPVRFVKTLEEEV 4725
Query: 176 -VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDA 234
V++G + L C+++ + W+++ ++V RI R L I D + DA
Sbjct: 4726 TVVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMR-ALTINDADDTDA 4782
Query: 235 GWYTVSAVN 243
G YTV+ N
Sbjct: 4783 GTYTVTVEN 4791
Score = 49.7 bits (117), Expect = 3e-06
Identities = 48/179 (26%), Positives = 73/179 (40%), Gaps = 14/179 (7%)
Query: 68 FIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFE 127
FI P+N+ I EG +S P V W + +T++S D + +I K L+ +
Sbjct: 6057 FISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIADGKK-RVLVVK 6114
Query: 128 VVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQ 187
D G Y + G A L V+ K P+ + +V E V C+
Sbjct: 6115 DATLQDMGTYVVMV----GAARAAAHLTVIEKLRIVVPL-----KDTRVKEQQEVVFNCE 6165
Query: 188 ISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
++ K W RN E + ++ I L +D TL I+D + D Y VS N G
Sbjct: 6166 VNT-EGAKAKWFRNEEAIFDSSKYIILQKDLV--YTLRIRDAHLDDQANYNVSLTNHRG 6221
Score = 49.7 bits (117), Expect = 3e-06
Identities = 34/133 (25%), Positives = 64/133 (48%), Gaps = 10/133 (7%)
Query: 67 RFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIF 126
R + P +M++ EG R G P P V+W G+ + + H++ ++ + F
Sbjct: 26065 RILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK---YKSTF 26121
Query: 127 EV--VRASDAGAYACVAKNRAG----EATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGD 180
E+ V+ASD G Y+ V +N G E T T+Q + ++ +P + P+ +V +
Sbjct: 26122 EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPE-PRVKSPE 26180
Query: 181 SVKLECQISAIPP 193
+VK ++ + P
Sbjct: 26181 AVKSPKRVKSPEP 26193
Score = 49.3 bits (116), Expect = 4e-06
Identities = 45/200 (22%), Positives = 85/200 (42%), Gaps = 17/200 (8%)
Query: 72 PENMSI-DEGR------FCRMDFKVSGLPAPDVSWYLNGRTVQSDD---LHKMIVSEKGL 121
PEN+ I D+G+ + R D+ +P++S+++ R SDD +HK + E
Sbjct: 11607 PENLHIADKGKTFVYLKWRRPDYDGG---SPNLSYHVERRLKGSDDWERVHKGSIKET-- 11661
Query: 122 HSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLE-GD 180
H ++ V + + KN GE+ + +V+ KE + P+ K ++ GD
Sbjct: 11662 HYMVDRCVE-NQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGD 11720
Query: 181 SVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVS 240
+++LE + P P++ W ++ + + + D G Y V+
Sbjct: 11721 TIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVT 11780
Query: 241 AVNEAGVTTCNTRLDVTARP 260
A N AG ++V +P
Sbjct: 11781 ATNTAGSFVAYATVNVLDKP 11800
Score = 48.9 bits (115), Expect = 6e-06
Identities = 57/257 (22%), Positives = 90/257 (35%), Gaps = 65/257 (25%)
Query: 64 YPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS 123
YPP I ++ EG+ R +VSG VSWY + ++ +M E
Sbjct: 3297 YPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQL 3355
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE---HKR----------------- 163
I E D G Y VA N G+ + T L + A E H+R
Sbjct: 3356 EIAEAY-PEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFL 3414
Query: 164 --------------------------APMFIYKPQSKK---------------VLEGDSV 182
+P++ K S+K + GD
Sbjct: 3415 SAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVA 3474
Query: 183 KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAV 242
L + IP PK+ W N ++ + D ++ + +L+I +D G YT A
Sbjct: 3475 TLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH--SLIILFTKLEDEGEYTCMAS 3532
Query: 243 NEAGVTTCNTRLDVTAR 259
N+ G T C+ L + ++
Sbjct: 3533 NDYGKTICSAYLKINSK 3549
Score = 48.5 bits (114), Expect = 8e-06
Identities = 50/182 (27%), Positives = 83/182 (45%), Gaps = 21/182 (11%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKG-LHSLIFEVVRA 131
+++++ G D ++S P V WYL G+ ++ D K++ +G +H+L V+
Sbjct: 5706 KDVTVTAGETATFDCELSYEDIP-VEWYLKGKKLEPSD--KVVPRSEGKVHTLTLRDVKL 5762
Query: 132 SDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKP-QSKKVLEGDSVKLECQISA 190
DAG AK+ A V K P+ KP + + V EG + LEC++S
Sbjct: 5763 EDAGEVQLTAKDFKTHANLFV---------KEPPVEFTKPLEDQTVEEGATAVLECEVSR 5813
Query: 191 IPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV-TLLIKDVNKKDAGWYTVSAVNEAGVTT 249
K+ W +N + + + + D GRV L+I D +D YT A + T+
Sbjct: 5814 -ENAKVKWFKNGTEI-LKSKKYEIVAD--GRVRKLVIHDCTPEDIKTYTCDAKDFK--TS 5867
Query: 250 CN 251
CN
Sbjct: 5868 CN 5869
Score = 48.5 bits (114), Expect = 8e-06
Identities = 33/111 (29%), Positives = 55/111 (49%), Gaps = 8/111 (7%)
Query: 51 GDVNDQDAIQEKFYPPRF---IQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTV- 106
G+V D ++++ P V + + + G R+ VSG P P V+W +N RT+
Sbjct: 10010 GEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLP 10069
Query: 107 QSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
Q + +S S++ + + S G Y+ +AKN AGE T+ +DVL
Sbjct: 10070 QEATIETTAISS----SMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVL 10116
Score = 47.4 bits (111), Expect = 2e-05
Identities = 32/114 (28%), Positives = 56/114 (49%), Gaps = 3/114 (2%)
Query: 175 KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDA 234
++LEG V C++S P PK+ W ++ + ++ + +R + GR +L I V +D
Sbjct: 1255 RILEGMGVTFHCKMSGYPLPKIAWYKDGKRIK-HGERYQMDFLQDGRASLRIPVVLPEDE 1313
Query: 235 GWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGLN 288
G YT A N G C+ +L V P L AP + S+ +L+ + ++
Sbjct: 1314 GIYTAFASNIKGNAICSGKLYV--EPAAPLGAPTYIPTLEPVSRIRSLSPRSVS 1365
Score = 47.4 bits (111), Expect = 2e-05
Identities = 47/196 (23%), Positives = 80/196 (40%), Gaps = 7/196 (3%)
Query: 55 DQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKM 114
D+ + P+ + ++ ++ +G +V G P P+ WY NG ++ D
Sbjct: 2021 DKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYW 2080
Query: 115 IVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK 174
E + L+ V A D+ + A N AGE + L V AK+ F + Q
Sbjct: 2081 YWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ---LITFTQELQDV 2137
Query: 175 KVLEGDSV-KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD 233
E D++ EC+ S P K+ W ++ M D+ ++ D L I ++ D
Sbjct: 2138 VAKEKDTMATFECETSE-PFVKVKWYKDG-MEVHEGDKYRMHSDRKVHF-LSILTIDTSD 2194
Query: 234 AGWYTVSAVNEAGVTT 249
A Y+ V + V T
Sbjct: 2195 AEDYSCVLVEDENVKT 2210
Score = 47.4 bits (111), Expect = 2e-05
Identities = 30/82 (36%), Positives = 42/82 (51%), Gaps = 2/82 (2%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G ++ IS P PK+ WK EM TDR+S+ R TL +KD + D+G Y
Sbjct: 22165 GSPFTIDVPISGRPAPKVTWKLE-EMRLKETDRVSI-TTTKDRTTLTVKDSMRGDSGRYF 22222
Query: 239 VSAVNEAGVTTCNTRLDVTARP 260
++ N AGV T + + V RP
Sbjct: 22223 LTLENTAGVKTFSVTVVVIGRP 22244
Score = 46.6 bits (109), Expect = 3e-05
Identities = 42/141 (29%), Positives = 74/141 (52%), Gaps = 14/141 (9%)
Query: 99 WYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLA 158
WY N ++S+ + I S +G +L + V D G Y+ V + + T +++
Sbjct: 2253 WYHNDVELKSNGKYT-ITSRRGRQNLTVKDVTKEDQGEYSFVIDGK--KTTCKLKM---- 2305
Query: 159 KEHKRAPMFIYKPQS-KKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQD 217
K P+ I + S +KV EGD V+LE ++S + + W ++ + VQ +DR+ + D
Sbjct: 2306 ---KPRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQ-PSDRVHIVID 2360
Query: 218 NTGRVTLLIKDVNKKDAGWYT 238
+ LLI+D+ K+DAG Y+
Sbjct: 2361 KQSHM-LLIEDMTKEDAGNYS 2380
Score = 46.6 bits (109), Expect = 3e-05
Identities = 41/178 (23%), Positives = 79/178 (44%), Gaps = 15/178 (8%)
Query: 67 RFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIF 126
+ I+ P++++ E + VS P V W+ ++ D H++ VSE+ +H L+
Sbjct: 2750 KIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRL-VSERKVHKLML 2807
Query: 127 EVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLEC 186
+ + SDAG Y V +A V+ + K K I P++K + EC
Sbjct: 2808 QNISPSDAGEYTAVVGQLECKAKLFVETLHITKTMKN----IEVPETK------TASFEC 2857
Query: 187 QISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
++S P + W +N ++ + + Q + L+I + + +D+ YT N+
Sbjct: 2858 EVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQ--LIIMNTSTEDSAEYTFVCGND 2912
Score = 46.6 bits (109), Expect = 3e-05
Identities = 40/148 (27%), Positives = 68/148 (45%), Gaps = 12/148 (8%)
Query: 41 SQVRSRSTSRGDVN--------DQDAIQEKFYPPRF---IQVPENMSIDEGRFCRMDFKV 89
+Q + R+ +R VN D I + PPR + + +++ G +D V
Sbjct: 12763 AQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATV 12822
Query: 90 SGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEAT 149
G P P VSW +G ++ + KM + ++ L +L V D+G Y A+N +G +
Sbjct: 12823 FGKPMPTVSWKKDGTLLKPAEGIKMAM-QRNLCTLELFSVNRKDSGDYTITAENSSGSKS 12881
Query: 150 FTVQLDVLAKEHKRAPMFIYKPQSKKVL 177
T++L VL K A + I K S + +
Sbjct: 12882 ATIKLKVLDKPGPPASVKINKMYSDRAM 12909
Score = 46.2 bits (108), Expect = 4e-05
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 6/123 (4%)
Query: 141 AKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQISAIPPPKLF 197
A+N GE T + ++ V+A++ AP K E + +L+ I P P +
Sbjct: 13460 AENENGEGTPS-EITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVS 13518
Query: 198 WKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVT 257
WK+ + + +T R+S+ + + TL++ D K DAG YT++ N AG + V
Sbjct: 13519 WKKGEDPLATDT-RVSV-ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVV 13576
Query: 258 ARP 260
+P
Sbjct: 13577 GKP 13579
Score = 45.4 bits (106), Expect = 6e-05
Identities = 49/180 (27%), Positives = 84/180 (46%), Gaps = 25/180 (13%)
Query: 66 PRFIQVPENMS---IDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ-SDDLHKMIVSEKGL 121
PR I + + +S + EG +++ KVS L + + W +G+ VQ SD +H IV +K
Sbjct: 2307 PRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVH--IVIDKQS 2363
Query: 122 HSLIFEVVRASDAGAYA----CVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL 177
H L+ E + DAG Y+ + + +G + +DV+ P+ + V+
Sbjct: 2364 HMLLIEDMTKEDAGNYSFTIPALGLSTSGRVS-VYSVDVIT------PL-----KDVNVI 2411
Query: 178 EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
EG LEC++S + W N+E ++ DR+ T + L+I + D G Y
Sbjct: 2412 EGTKAVLECKVSVPDVTSVKWYLNDEQIK-PDDRVQAIVKGT-KQRLVINRTHASDEGPY 2469
Score = 45.1 bits (105), Expect = 8e-05
Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP + QS+ V +G ++ P P+ W +N ++ +DRI Y
Sbjct: 2031 APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIE-RSDRIYWYWPEDNVCE 2089
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 259
L+I+DV +D+ V A+N AG T+ + L V A+
Sbjct: 2090 LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2125
Score = 45.1 bits (105), Expect = 8e-05
Identities = 41/174 (23%), Positives = 71/174 (40%), Gaps = 19/174 (10%)
Query: 79 EGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYA 138
EG + +P P VSW+ +G+ V++ D M H + + VRA DAG Y
Sbjct: 7903 EGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRA-DAGIYT 7961
Query: 139 CVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPP----- 193
+N+ G AT ++ + V+ K + D K C+++ PP
Sbjct: 7962 ITLENKLGSATASINVKVIG----------LPGPCKDIKASDITKSSCKLTWEPPEFDGG 8011
Query: 194 -PKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
P L + T + +N +++ +KD+ ++ V AVN+ G
Sbjct: 8012 TPILHYVLERREAGRRTYIPVMSGEN--KLSWTVKDLIPNGEYFFRVKAVNKVG 8063
Score = 45.1 bits (105), Expect = 8e-05
Identities = 24/86 (27%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Query: 175 KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDA 234
K G SVKL IS P P + W ++++ +Q T+ + ++ T ++LIKD ++ ++
Sbjct: 20386 KYRAGTSVKLRAGISGKPAPTIEWYKDDKELQ--TNALVCVENTTDLASILIKDADRLNS 20443
Query: 235 GWYTVSAVNEAGVTTCNTRLDVTARP 260
G Y + N G + R+ + +P
Sbjct: 20444 GCYELKLRNAMGSASATIRVQILDKP 20469
Score = 44.3 bits (103), Expect = 1e-04
Identities = 52/193 (26%), Positives = 79/193 (40%), Gaps = 18/193 (9%)
Query: 67 RFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIF 126
+F+ E+ ++ EG ++S V W+ N + + +I SE H L
Sbjct: 5078 KFMSPLEDQTVKEGETATFVCELSH-EKMHVVWFKNDAKLHTSRT-VLISSEGKTHKLEM 5135
Query: 127 EVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLEC 186
+ V D K E + T QL VL + P F K K +E D + L+C
Sbjct: 5136 KEVTLDDISQIKAQVK----ELSSTAQLKVLEAD----PYFTVKLHDKTAVEKDEITLKC 5187
Query: 187 QISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
++S P K F K E+V + + S+ D R+ L IK + KD G Y V + G
Sbjct: 5188 EVSKDVPVKWF-KDGEEIVP--SPKYSIKADGLRRI-LKIKKADLKDKGEY----VCDCG 5239
Query: 247 VTTCNTRLDVTAR 259
+ V AR
Sbjct: 5240 TDKTKANVTVEAR 5252
Score = 44.3 bits (103), Expect = 1e-04
Identities = 27/101 (26%), Positives = 43/101 (42%), Gaps = 4/101 (3%)
Query: 60 QEKFYPPRF---IQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIV 116
QEK PP +++ E + + G R + G+P P W +G +++D+ H +
Sbjct: 11005 QEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDE-HYTVE 11063
Query: 117 SEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
++ L + D G Y N AG T V L VL
Sbjct: 11064 TDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVL 11104
Score = 44.3 bits (103), Expect = 1e-04
Identities = 36/144 (25%), Positives = 67/144 (46%), Gaps = 4/144 (2%)
Query: 119 KGLHSLIFEVVRASDAGAYACVAKNRAGEAT-FTVQLDVLAKEHKRAPMFIYKPQSKKVL 177
K L ++I + + + + VA N G + ++ + ++AK+ P S V
Sbjct: 16687 KSLQAVITNLTQGEEY-LFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQ 16745
Query: 178 EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
G +K+E IS P P + W ++ ++ T RI++ D+ TL IK+ +K D G Y
Sbjct: 16746 VGQDLKIEVPISGRPKPTITWTKDGLPLK-QTTRINV-TDSLDLTTLSIKETHKDDGGQY 16803
Query: 238 TVSAVNEAGVTTCNTRLDVTARPN 261
++ N G T + + +P+
Sbjct: 16804 GITVANVVGQKTASIEIVTLDKPD 16827
Score = 43.9 bits (102), Expect = 2e-04
Identities = 27/106 (25%), Positives = 53/106 (50%), Gaps = 2/106 (1%)
Query: 155 DVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISL 214
+V+AK+ P + V+EG+ + + A+P P + W ++ + V+ +DR+++
Sbjct: 7880 NVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVK-ASDRLTM 7938
Query: 215 YQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARP 260
D+ + K V + DAG YT++ N+ G T + + V P
Sbjct: 7939 KNDHISAHLEVPKSV-RADAGIYTITLENKLGSATASINVKVIGLP 7983
Score = 43.9 bits (102), Expect = 2e-04
Identities = 44/180 (24%), Positives = 77/180 (42%), Gaps = 19/180 (10%)
Query: 137 YACVAKNRAGEATFTVQLD----VLAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQIS 189
+ +A+N AG F+ D + A++ AP P+ K V+ G++ LE I
Sbjct: 18178 FRVIARNAAGN--FSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIR 18235
Query: 190 AIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTT 249
P P + W ++ + ++ R+ + + + TL++KD + D G Y + N G +
Sbjct: 18236 GKPIPDVVWSKDGKELEETAARMEI-KSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKS 18294
Query: 250 CNTRLDVTARPNQTLPAPKQLRVRPTFSK--YLA----LNGKGLNVKQAFNPEGEFQRLA 303
+ V RP P L+V ++ YLA L G N+ + E RL+
Sbjct: 18295 IPITVKVLDRPG---PPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS 18351
Score = 43.1 bits (100), Expect = 3e-04
Identities = 51/200 (25%), Positives = 85/200 (42%), Gaps = 25/200 (12%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P F++ E+ ++ E ++S A +V WY NGR ++ +K + +H L
Sbjct: 6325 PTEFVEHLEDQTVTEFDDAVFSCQLSREKA-NVKWYRNGREIKEGKKYKF-EKDGSIHRL 6382
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL---EGDS 181
I + R D YAC ++R A V + + E R P I + V+ E +
Sbjct: 6383 IIKDCRLDDECEYACGVEDRKSRARLFV--EEIPVEIIRPPQDILEAPGADVVFLAELNK 6440
Query: 182 VKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV-TLLIKDVNKKDAGWYTVS 240
K+E Q W RNN MV D+ + + G++ L I D+ +D G Y
Sbjct: 6441 DKVEVQ----------WLRNN-MVVVQGDKHQMMSE--GKIHRLQICDIKPRDQGEYRFI 6487
Query: 241 AVNEAGVTTCNTRLDVTARP 260
A ++ +L++ A P
Sbjct: 6488 AKDK----EARAKLELAAAP 6503
Score = 43.1 bits (100), Expect = 3e-04
Identities = 32/135 (23%), Positives = 64/135 (47%), Gaps = 6/135 (4%)
Query: 115 IVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK 174
I + KGL ++ + + + +A N AG + V+ KE P + +
Sbjct: 14517 ITTVKGLECVVRNLTEGEEY-TFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQ 14575
Query: 175 KVL---EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNK 231
K++ GD++K+E + P P + WK+ +++++ T R++ T + L I + +
Sbjct: 14576 KLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILK-QTQRVNFETTATSTI-LNINECVR 14633
Query: 232 KDAGWYTVSAVNEAG 246
D+G Y ++A N G
Sbjct: 14634 SDSGPYPLTARNIVG 14648
Score = 42.4 bits (98), Expect = 5e-04
Identities = 29/102 (28%), Positives = 50/102 (49%), Gaps = 10/102 (9%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYL-------NGRTVQSD-DLHKMIVS 117
P I + E M ++EG + K+ G+P P ++W+ N V D ++K++V
Sbjct: 9620 PPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD 9679
Query: 118 EKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
+ +L+ R SD G Y A N G A+ ++L+VL +
Sbjct: 9680 D--TCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGR 9719
Score = 42.0 bits (97), Expect = 7e-04
Identities = 34/128 (26%), Positives = 56/128 (43%), Gaps = 8/128 (6%)
Query: 141 AKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK---KVLEGDSVKLECQISAIPPPKLF 197
A N AGE V E + P K +++ G ++++ ++ P P
Sbjct: 8581 AVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKV 8640
Query: 198 WKRNNEMVQFNTDRISLYQDNTG-RVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
W + E + + DR+ + DN G + L+IKD +KD G Y ++A N G R++V
Sbjct: 8641 WTK--EEGELDKDRVVI--DNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 8696
Query: 257 TARPNQTL 264
P L
Sbjct: 8697 FDVPGPVL 8704
Score = 42.0 bits (97), Expect = 7e-04
Identities = 52/193 (26%), Positives = 78/193 (40%), Gaps = 23/193 (11%)
Query: 93 PAPDVSWYLNGRTVQSDDLHK---MIVSEKGLHSLIFEVVRASDAGAYA--CVAKNRAG- 146
P D L G V+ DL M + + F V + G Y AKN AG
Sbjct: 13800 PKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGA 13859
Query: 147 -----EATFTVQLDVLAKEHKRAPMFIYKPQSKKVLE---GDSVKLEC-QISAIPPPKLF 197
E+T T+ + K+ AP + P K L GD++ L I P PK
Sbjct: 13860 ISAPSESTETI----ICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSS 13915
Query: 198 WKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVT 257
W + + ++ +D + T + L IK +KDAG YT++A N G + ++ V
Sbjct: 13916 WSKAGKDIR-PSDITQITSTPTSSM-LTIKYATRKDAGEYTITATNPFGTKVEHVKVTVL 13973
Query: 258 ARPNQTLPAPKQL 270
P P P ++
Sbjct: 13974 DVPGP--PGPVEI 13984
Score = 42.0 bits (97), Expect = 7e-04
Identities = 28/99 (28%), Positives = 46/99 (46%), Gaps = 2/99 (2%)
Query: 59 IQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSE 118
+ K + P+ ++ + G + SG P P ++W G+ + ++ H ++
Sbjct: 24524 VPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQ-KGQDLIDNNGHYQVIVT 24582
Query: 119 KGLHSLIF-EVVRASDAGAYACVAKNRAGEATFTVQLDV 156
+ SL+F V DAG Y AKNR G TV+LDV
Sbjct: 24583 RSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 24621
Score = 41.2 bits (95), Expect = 0.001
Identities = 28/108 (25%), Positives = 48/108 (44%), Gaps = 2/108 (1%)
Query: 60 QEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEK 119
+E+ PP+ + +PE ++I G+ R++ V G P P W G H +
Sbjct: 12397 KEQLLPPKIL-MPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKAD 12454
Query: 120 GLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMF 167
LI + V D+G Y+ A+N +G T +++ V+ P F
Sbjct: 12455 SSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 12502
Score = 41.2 bits (95), Expect = 0.001
Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 6/102 (5%)
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V G +V L+ + P P + WK++ +++ Q N TL + VN+KD+G
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNL--CTLELFSVNRKDSG 12867
Query: 236 WYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFS 277
YT++A N +G + +L V +P P +++ +S
Sbjct: 12868 DYTITAENSSGSKSATIKLKVLDKPG----PPASVKINKMYS 12905
Score = 41.2 bits (95), Expect = 0.001
Identities = 39/150 (26%), Positives = 63/150 (42%), Gaps = 17/150 (11%)
Query: 47 STSRGDVNDQDAIQEKFYPPRFIQVP---ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNG 103
S S G + +D + PPR P + + + G ++D + G P P + W + G
Sbjct: 16029 SESTGAITARDEVD----PPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQW-IKG 16083
Query: 104 RTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKR 163
S+ I S SL + D+G Y AKN AGE + TV + VL +
Sbjct: 16084 DQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPG-- 16141
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPP 193
P+ V+ G + + +C ++ PP
Sbjct: 16142 ------PPEGPVVISGVTAE-KCTLAWKPP 16164
Score = 41.2 bits (95), Expect = 0.001
Identities = 21/86 (24%), Positives = 36/86 (41%)
Query: 171 PQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVN 230
P + EG + + C + P P++ W + ++ TL+I DV
Sbjct: 26838 PSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQ 26897
Query: 231 KKDAGWYTVSAVNEAGVTTCNTRLDV 256
K+D G YT+S NE G + + +
Sbjct: 26898 KQDGGLYTLSLGNEFGSDSATVNIHI 26923
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/204 (20%), Positives = 72/204 (35%), Gaps = 37/204 (18%)
Query: 90 SGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAG--- 146
S L A +V+WY +G+ ++ + + S G + L + SD G Y C G
Sbjct: 26245 SVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSK 26304
Query: 147 -------------------------------EATFTVQLDVLAKEH-KRAPMFIYKPQSK 174
E+T T + + A E P+ + Q
Sbjct: 26305 TNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDT 26364
Query: 175 KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDA 234
V K + + P P W ++ + + + L +D G L I + D+
Sbjct: 26365 TVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT-QGGKYKLSEDK-GGFFLEIHKTDTSDS 26422
Query: 235 GWYTVSAVNEAGVTTCNTRLDVTA 258
G YT + N AG + + +L + A
Sbjct: 26423 GLYTCTVKNSAGSVSSSCKLTIKA 26446
Score = 40.4 bits (93), Expect = 0.002
Identities = 30/129 (23%), Positives = 60/129 (46%), Gaps = 7/129 (5%)
Query: 137 YACVAKNRAGEATFTVQLD--VLAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQISAI 191
+ +AKN AG + + + ++ AP + K + G++ +LE +S
Sbjct: 14932 FRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGR 14991
Query: 192 PPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCN 251
PPP + W ++ + ++ T ++ + + L+ KD ++D+G YT++A N G
Sbjct: 14992 PPPTMEWSKDGKELE-GTAKLEIKIADFS-TNLVNKDSTRRDSGAYTLTATNPGGFAKHI 15049
Query: 252 TRLDVTARP 260
+ V RP
Sbjct: 15050 FNVKVLDRP 15058
Score = 40.4 bits (93), Expect = 0.002
Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Query: 152 VQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDR 211
+ + V+AK+ P F + VL G+ +K++ P P + W ++N ++ T R
Sbjct: 15638 LSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLK-QTTR 15696
Query: 212 ISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
++ + L IKD ++D G Y V N AG
Sbjct: 15697 VNA-ESTENNSLLTIKDACREDVGHYVVKLTNSAG 15730
Score = 40.4 bits (93), Expect = 0.002
Identities = 21/86 (24%), Positives = 38/86 (44%), Gaps = 1/86 (1%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 132
++ ++ + K +G P P W +G+ + +K+ +KG L S
Sbjct: 26362 QDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS-EDKGGFFLEIHKTDTS 26420
Query: 133 DAGAYACVAKNRAGEATFTVQLDVLA 158
D+G Y C KN AG + + +L + A
Sbjct: 26421 DSGLYTCTVKNSAGSVSSSCKLTIKA 26446
Score = 40.0 bits (92), Expect = 0.003
Identities = 39/163 (23%), Positives = 66/163 (40%), Gaps = 16/163 (9%)
Query: 97 VSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDV 156
V W+ N + + + M E HS+ F+ + D A + EA TV
Sbjct: 5462 VKWFKNDQRLHTTRSVSM-QDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVL--- 5517
Query: 157 LAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQ 216
+ P F K Q +E D V L+C+IS P ++K E+ + ++ +
Sbjct: 5518 -----EGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEI---KPSKNAVIK 5569
Query: 217 DNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 259
+ + L++K K D G YT + G + +LD+ R
Sbjct: 5570 ADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDIEDR 5608
Score = 40.0 bits (92), Expect = 0.003
Identities = 32/142 (22%), Positives = 62/142 (43%), Gaps = 14/142 (9%)
Query: 122 HSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL---E 178
H F V+ + AG ++ +++ + A++ P P+ K +
Sbjct: 16010 HRYEFRVIARNAAGVFSEPSESTGA---------ITARDEVDPPRISMDPKYKDTIVVHA 16060
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G+S K++ I P P + W + ++ + NT R+ + + +L +KD + D+G Y
Sbjct: 16061 GESFKVDADIYGKPIPTIQWIKGDQELS-NTARLEIKSTDFA-TSLSVKDAVRVDSGNYI 16118
Query: 239 VSAVNEAGVTTCNTRLDVTARP 260
+ A N AG + + V RP
Sbjct: 16119 LKAKNVAGERSVTVNVKVLDRP 16140
Score = 40.0 bits (92), Expect = 0.003
Identities = 30/129 (23%), Positives = 58/129 (44%), Gaps = 7/129 (5%)
Query: 137 YACVAKNRAGEATFTVQLD--VLAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQISAI 191
+ +AKN AG + + AK+ P P+ + + G++ +LE +
Sbjct: 17096 FRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGK 17155
Query: 192 PPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCN 251
P P + W R ++ ++ + R + ++ + L++KD + D G Y + A N AG +
Sbjct: 17156 PLPTIEWLRGDKEIE-ESARCEI-KNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFP 17213
Query: 252 TRLDVTARP 260
+ V RP
Sbjct: 17214 VNVKVLDRP 17222
Score = 40.0 bits (92), Expect = 0.003
Identities = 24/98 (24%), Positives = 41/98 (41%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F ++ N EG+ + +VSG+P P + W +G+ + ++I ++L
Sbjct: 25298 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25357
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKR 163
D G Y A N AG + L V +K+
Sbjct: 25358 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25395
Score = 39.7 bits (91), Expect = 0.004
Identities = 40/158 (25%), Positives = 61/158 (38%), Gaps = 13/158 (8%)
Query: 93 PAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTV 152
P V W + + +Q D K I EK +H L+ R SDAG Y VA A V
Sbjct: 3038 PDITVQWMKDDQELQITDRIK-IQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFV 3096
Query: 153 Q-LDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDR 211
+ DV + K+ I K ++ E + ++ W ++ + F
Sbjct: 3097 EGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAH----------WYKDGIEINFQVQE 3146
Query: 212 ISLYQDNTGRVTLLIKDVNKKDAGWYT-VSAVNEAGVT 248
Y + I + + DAG YT V+ N + VT
Sbjct: 3147 RHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVT 3184
Score = 39.7 bits (91), Expect = 0.004
Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 2/82 (2%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G ++++ ++ P P + W + +++ R+ L QD RV L IK+ + D G Y
Sbjct: 11426 GQTIRILARVKGRPEPDITWTKEGKVL-VREKRVDLIQD-LPRVELQIKEAVRADHGKYI 11483
Query: 239 VSAVNEAGVTTCNTRLDVTARP 260
+SA N +G + ++V RP
Sbjct: 11484 ISAKNSSGHAQGSAIVNVLDRP 11505
Score = 39.7 bits (91), Expect = 0.004
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 1/76 (1%)
Query: 84 RMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKN 143
R+ + G PAP VSW G + D + S +LI + SDAG Y KN
Sbjct: 13504 RLKIPIKGKPAPSVSWK-KGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKN 13562
Query: 144 RAGEATFTVQLDVLAK 159
AG T+ + V+ K
Sbjct: 13563 VAGTKEGTISIKVVGK 13578
Score = 39.7 bits (91), Expect = 0.004
Identities = 21/91 (23%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 69 IQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEV 128
++ E + G ++ +SG PAP + WY + + +Q++ L + + L S++ +
Sbjct: 20379 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNAL-VCVENTTDLASILIKD 20437
Query: 129 VRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
++G Y +N G A+ T+++ +L K
Sbjct: 20438 ADRLNSGCYELKLRNAMGSASATIRVQILDK 20468
Score = 39.7 bits (91), Expect = 0.004
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKD-VNKKDAGWY 237
G S++L +S PPP + W + + + I D T +LLI D VN+ DAG Y
Sbjct: 22964 GASLRLMVSVSGRPPPVITWSKQG--IDLASRAII---DTTESYSLLIVDKVNRYDAGKY 23018
Query: 238 TVSAVNEAGVTTCNTRLDVTARP 260
T+ A N++G + + V P
Sbjct: 23019 TIEAENQSGKKSATVLVKVYDTP 23041
Score = 39.3 bits (90), Expect = 0.005
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 2/85 (2%)
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V G ++L ++ P PK+ W + +M+ RI++ ++ + T+ I D + D G
Sbjct: 7205 VKAGTKIELPATVTGKPEPKITWTKA-DMILKQDKRITI-ENVPKKSTVTIVDSKRSDTG 7262
Query: 236 WYTVSAVNEAGVTTCNTRLDVTARP 260
Y + AVN G T ++V +P
Sbjct: 7263 TYIIEAVNVCGRATAVVEVNVLDKP 7287
Score = 39.3 bits (90), Expect = 0.005
Identities = 36/140 (25%), Positives = 63/140 (45%), Gaps = 12/140 (8%)
Query: 137 YACVAKNRAGEATFT-VQLDVLAKEHKRAPMFIYKP---QSKKVLEGDSVKLECQISAIP 192
+ +A N AGE+ V VL K+ P I + + + GD+++L I +P
Sbjct: 10690 FRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVP 10749
Query: 193 PPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
PK+ WK+ + RI + + L I++ +D G Y+++ N AG T +
Sbjct: 10750 FPKVTWKKEDRDAPTKA-RIDVTPVGS---KLEIRNAAHEDGGIYSLTVENPAGSKTVSV 10805
Query: 253 RLDVTARPNQTLPAPKQLRV 272
++ V +P P+ L V
Sbjct: 10806 KVLVLDKPG----PPRDLEV 10821
Score = 39.3 bits (90), Expect = 0.005
Identities = 37/128 (28%), Positives = 62/128 (48%), Gaps = 14/128 (10%)
Query: 141 AKNRAGEAT-FTVQLDVLAKEHKRAP---MFIYKPQSKKVLEGDSVKLECQISAIPPPKL 196
A+N+AG + + L VL KE P M + + V G ++K++ IS P PK+
Sbjct: 19952 AENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKV 20011
Query: 197 FWKRNN----EMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
R+ ++FNT+ + +N +T+ +K+ DAG Y ++A N +G T
Sbjct: 20012 TLSRDGVPLKATMRFNTE---ITAEN---LTINLKESVTADAGRYEITAANSSGTTKAFI 20065
Query: 253 RLDVTARP 260
+ V RP
Sbjct: 20066 NIVVLDRP 20073
Score = 38.9 bits (89), Expect = 0.006
Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Query: 75 MSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDA 134
+++ G+ R+ +V G P PD++W G+ + + +I + I E VRA D
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA-DH 11479
Query: 135 GAYACVAKNRAGEATFTVQLDVL 157
G Y AKN +G A + ++VL
Sbjct: 11480 GKYIISAKNSSGHAQGSAIVNVL 11502
Score = 38.9 bits (89), Expect = 0.006
Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 1/75 (1%)
Query: 85 MDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNR 144
+D +SG PAP V+W L ++ D I + K +L + D+G Y +N
Sbjct: 22170 IDVPISGRPAPKVTWKLEEMRLKETD-RVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 22228
Query: 145 AGEATFTVQLDVLAK 159
AG TF+V + V+ +
Sbjct: 22229 AGVKTFSVTVVVIGR 22243
Score = 38.5 bits (88), Expect = 0.008
Identities = 42/153 (27%), Positives = 60/153 (39%), Gaps = 16/153 (10%)
Query: 92 LPAPDV--SWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEAT 149
L PDV W L G+ + + ++I K H LI + G + A N A
Sbjct: 5277 LSEPDVHGQWKLKGQPLTASPDCEIIEDGKK-HILILHNCQLGMTGEVSFQAANAKSAAN 5335
Query: 150 FTVQLDVLAKEHKRAPMFIYKPQSK-KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFN 208
V K P+ P S KV E D K EC++S P + K E+
Sbjct: 5336 LKV---------KELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEIT--G 5384
Query: 209 TDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSA 241
DR L +D T + +++IK +D Y A
Sbjct: 5385 DDRFELIKDGT-KHSMVIKSAAFEDEAKYMFEA 5416
Score = 38.5 bits (88), Expect = 0.008
Identities = 26/138 (18%), Positives = 62/138 (44%), Gaps = 9/138 (6%)
Query: 133 DAGAYACVAKNRAGEATFTVQLD--VLAKEHKRAPMFIYKPQ---SKKVLEGDSVKLECQ 187
D + +A+N G + Q ++ ++ P+ + P+ + G+S++++
Sbjct: 21425 DRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKAL 21484
Query: 188 ISAIPPPKLFWKRNNEMVQFNTDRISL-YQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
+ P P++ W ++ ++ R+++ D G +L ++D + G YTV A N +G
Sbjct: 21485 VQGRPVPRVTWFKDGVEIE---KRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASG 21541
Query: 247 VTTCNTRLDVTARPNQTL 264
++ V P + +
Sbjct: 21542 SAKAEIKVKVQDTPGKVV 21559
Score = 38.5 bits (88), Expect = 0.008
Identities = 21/82 (25%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G + L+ + P PK+ W + ++ + +++SL Q R T +IK ++ D+G YT
Sbjct: 22565 GSDLVLDAAVGGKPEPKIIWTKGDKELDL-CEKVSL-QYTGKRATAVIKFCDRSDSGKYT 22622
Query: 239 VSAVNEAGVTTCNTRLDVTARP 260
++ N +G + + V P
Sbjct: 22623 LTVKNASGTKAVSVMVKVLDSP 22644
Score = 38.5 bits (88), Expect = 0.008
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 132
+ ++I G R+ VSG P P ++W G + S +I + + LI + V
Sbjct: 22957 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLAS---RAIIDTTESYSLLIVDKVNRY 23013
Query: 133 DAGAYACVAKNRAGEATFTVQLDV 156
DAG Y A+N++G+ + TV + V
Sbjct: 23014 DAGKYTIEAENQSGKKSATVLVKV 23037
Score = 38.1 bits (87), Expect = 0.010
Identities = 29/115 (25%), Positives = 42/115 (36%), Gaps = 12/115 (10%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
A + KP+S V EG+S + C P P + W R +++ +T + T
Sbjct: 26063 AARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVL--STSARHQVTTTKYKST 26120
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCN----------TRLDVTARPNQTLPAPK 268
I V D G Y+V N G T VT+ P P P+
Sbjct: 26121 FEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPR 26175
Score = 37.7 bits (86), Expect = 0.013
Identities = 24/69 (34%), Positives = 37/69 (53%), Gaps = 4/69 (5%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLL-IKDVNKKDAGWY 237
G +++L + PPPK+ W + N ++ DRI L +T T L ++VNK DAG Y
Sbjct: 13211 GVTMRLYVPVKGRPPPKITWSKPNVNLR---DRIGLDIKSTDFDTFLRCENVNKYDAGKY 13267
Query: 238 TVSAVNEAG 246
++ N G
Sbjct: 13268 ILTLENSCG 13276
Score = 37.7 bits (86), Expect = 0.013
Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 11/92 (11%)
Query: 157 LAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTD-RI 212
+AKE + P+F + +K L G S + P P + W + + TD R
Sbjct: 19679 IAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPD------TDLRT 19732
Query: 213 SLYQDNT-GRVTLLIKDVNKKDAGWYTVSAVN 243
Y D T R +L I++ N+ D+G YT++ N
Sbjct: 19733 RAYVDTTDSRTSLTIENANRNDSGKYTLTIQN 19764
Score = 37.4 bits (85), Expect = 0.017
Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 3/99 (3%)
Query: 64 YPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ-SDDLHKMIVSEKGLH 122
+ PR + + G+ R V P +V WY NG +Q S +H + G+
Sbjct: 25875 HAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIH--YTNTSGVL 25932
Query: 123 SLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEH 161
+L D+G Y V N GEA+ LDV ++
Sbjct: 25933 TLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDY 25971
Score = 37.0 bits (84), Expect = 0.023
Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
Query: 69 IQVPENM-SIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI-F 126
+++P N SI G +++ V G P P++SW +G ++ ++ V E +++
Sbjct: 17817 LKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTT--RVNVEETATSTVLHI 17874
Query: 127 EVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
+ D G Y A N AG AT + + VL K
Sbjct: 17875 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 17907
Score = 37.0 bits (84), Expect = 0.023
Identities = 28/120 (23%), Positives = 54/120 (45%), Gaps = 8/120 (6%)
Query: 43 VRSRSTSRGDVNDQDAIQEKFYPPRF---IQVPENMSIDEGRFCRMDFKVSGLPAPDVSW 99
V S S G + +D ++ PPR ++ + + + G +++ ++G P P +SW
Sbjct: 19271 VSEPSESTGPIIVKDDVE----PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISW 19326
Query: 100 YLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
+G ++ ++I ++ + + +R D G Y KN AG + V VL K
Sbjct: 19327 AKDGIEIEERARTEIISTDNHTLLTVKDCIR-RDTGQYVLTLKNVAGTRSVAVNCKVLDK 19385
Score = 36.6 bits (83), Expect = 0.030
Identities = 38/139 (27%), Positives = 63/139 (45%), Gaps = 15/139 (10%)
Query: 141 AKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVL---EGDSVKLECQISAIPPPKLF 197
A N AG V DV E + AP F + ++ L G S+++ I P P++
Sbjct: 14253 AINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVT 14312
Query: 198 WKRNNEMVQFNTDRISLYQDNTGRVTLL-IKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
W ++N ++ +R ++ +NT TLL I + N+ D G + ++ N AG + + V
Sbjct: 14313 WTKDNINLK---NRANI--ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRV 14367
Query: 257 TARPNQTLPAPKQLRVRPT 275
P L +RPT
Sbjct: 14368 LDTPGPV------LNLRPT 14380
Score = 36.6 bits (83), Expect = 0.030
Identities = 30/132 (22%), Positives = 55/132 (41%), Gaps = 5/132 (3%)
Query: 163 RAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV 222
+AP F + ++ V + L C+++ P P + W R + + + + + + G
Sbjct: 24429 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 24488
Query: 223 TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLAL 282
L+I V DA Y V A N+ G + L+V LP + AL
Sbjct: 24489 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLP-----KTLEGMGAVHAL 24543
Query: 283 NGKGLNVKQAFN 294
G+ +++K F+
Sbjct: 24544 RGEVVSIKIPFS 24555
Score = 35.8 bits (81), Expect = 0.051
Identities = 30/120 (25%), Positives = 56/120 (46%), Gaps = 12/120 (10%)
Query: 47 STSRGDVNDQDAIQEKFYPPRFIQV--PENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGR 104
S + G++ D IQE+ P FI + + + G R+ + G P P SW +G+
Sbjct: 9296 SDTTGEIPATD-IQEE--PEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGK 9352
Query: 105 TVQS--DDLHKM-----IVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
++ D +H + + + + +I + S G Y+ AKN+AG+ T ++ V+
Sbjct: 9353 AKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVM 9412
Score = 35.8 bits (81), Expect = 0.051
Identities = 25/95 (26%), Positives = 43/95 (45%), Gaps = 5/95 (5%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P + + ++I G + + SG P P VSW+ + V DD + + +L
Sbjct: 10321 PTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPA---TL 10377
Query: 125 IFEVVRA--SDAGAYACVAKNRAGEATFTVQLDVL 157
E ++A SD+G Y V +N G Q++V+
Sbjct: 10378 ALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVV 10412
Score = 35.8 bits (81), Expect = 0.051
Identities = 22/84 (26%), Positives = 36/84 (42%), Gaps = 1/84 (1%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 132
+ + I G R+ V G P P V+W+ +G ++ ++ I G SL
Sbjct: 21469 DGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEK-RMNMEITDVLGSTSLFVRDATRD 21527
Query: 133 DAGAYACVAKNRAGEATFTVQLDV 156
G Y AKN +G A +++ V
Sbjct: 21528 HRGVYTVEAKNASGSAKAEIKVKV 21551
Score = 35.4 bits (80), Expect = 0.066
Identities = 24/100 (24%), Positives = 44/100 (44%), Gaps = 10/100 (10%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT------LLIKDVNKK 232
G +++ I P PK W+ + + + D + ++ T ++I + +
Sbjct: 9328 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9387
Query: 233 DAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRV 272
G Y+++A N+AG T N R+ V P PK L+V
Sbjct: 9388 HTGKYSITAKNKAGQKTANCRVKVMDVPG----PPKDLKV 9423
Score = 35.4 bits (80), Expect = 0.066
Identities = 42/166 (25%), Positives = 70/166 (42%), Gaps = 16/166 (9%)
Query: 114 MIVSEKGLHSLIFEVVRASDAGAY--ACVAKNRAGEATFT-VQLDVLAKEHKRAPMFIYK 170
M G++ EV + + Y A N+AG V ++ +E AP
Sbjct: 16389 MCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLD 16448
Query: 171 PQSKKVLE---GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIK 227
+ +K++ G S++L I P P++ W + + + R + D T T L+
Sbjct: 16449 LELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEI-----RDAAIIDVTSSFTSLVL 16503
Query: 228 D-VNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRV 272
D VN+ D+G YT++ N +G + VT R T P L+V
Sbjct: 16504 DNVNRYDSGKYTLTLENSSGTKSA----FVTVRVLDTPSPPVNLKV 16545
Score = 35.4 bits (80), Expect = 0.066
Identities = 25/110 (22%), Positives = 50/110 (45%), Gaps = 2/110 (1%)
Query: 156 VLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLY 215
V+A++ + P + V + +K++ P + W+++ + ++ T R+++
Sbjct: 18889 VIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLK-ETTRVNVS 18947
Query: 216 QDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLP 265
T +L IK+ +K+D G Y + N AG T + V RP P
Sbjct: 18948 SSKTV-TSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGP 18996
Score = 35.4 bits (80), Expect = 0.066
Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 1/85 (1%)
Query: 84 RMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKN 143
++D G P V+W +G+T++ + + S K + SL + D G Y N
Sbjct: 18916 KIDVPFKGRPQATVNWRKDGQTLK-ETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSN 18974
Query: 144 RAGEATFTVQLDVLAKEHKRAPMFI 168
AG T + + VL + P+ I
Sbjct: 18975 SAGSITVPITIIVLDRPGPPGPIRI 18999
Score = 35.4 bits (80), Expect = 0.066
Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP + +S +V G + + + + P ++ W N +Q + +I Y + +G +T
Sbjct: 25876 APRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQ-ESSKIH-YTNTSGVLT 25933
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVT 257
L I D + D+G Y N G + LDVT
Sbjct: 25934 LEILDCHTDDSGTYRAVCTNYKGEASDYATLDVT 25967
Score = 35.0 bits (79), Expect = 0.086
Identities = 26/114 (22%), Positives = 50/114 (43%), Gaps = 8/114 (7%)
Query: 47 STSRGDVNDQDAIQEKFYPPRFIQVP---ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNG 103
S S G + +D ++ PR P + + ++ G R++ V G P P + W
Sbjct: 17111 SDSTGPITAKDEVEL----PRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGD 17166
Query: 104 RTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
+ ++ ++ ++ ++ + +R D G Y A N AG +F V + VL
Sbjct: 17167 KEIEESARCEIKNTDFKALLIVKDAIRI-DGGQYILRASNVAGSKSFPVNVKVL 17219
Score = 34.7 bits (78), Expect = 0.11
Identities = 22/104 (21%), Positives = 44/104 (42%), Gaps = 5/104 (4%)
Query: 56 QDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMI 115
+D + E P F + S+ G+ +++ +SG P P ++W +G ++ +
Sbjct: 16727 KDLVIEPDVKPAF----SSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLK-QTTRINV 16781
Query: 116 VSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
L +L + D G Y N G+ T ++++ L K
Sbjct: 16782 TDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK 16825
Score = 34.3 bits (77), Expect = 0.15
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 3/69 (4%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGL-HSLIFEVVRA 131
+++++ EG ++ KVS V WYLN ++ DD + IV KG L+ A
Sbjct: 2406 KDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIV--KGTKQRLVINRTHA 2463
Query: 132 SDAGAYACV 140
SD G Y +
Sbjct: 2464 SDEGPYKLI 2472
Score = 34.3 bits (77), Expect = 0.15
Identities = 27/126 (21%), Positives = 55/126 (43%), Gaps = 12/126 (9%)
Query: 69 IQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEV 128
++ + + + G R++ VSG P P + W +G+ ++ ++ +++ +L+ +
Sbjct: 14968 VKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKD 15026
Query: 129 VRASDAGAYACVAKNRAGEATFTVQLDVLAKE-HKRAPMFIYKPQSKKVLEGDSVKLECQ 187
D+GAY A N G A + VL + P+ + + S+K C
Sbjct: 15027 STRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEK----------CV 15076
Query: 188 ISAIPP 193
+S PP
Sbjct: 15077 LSWFPP 15082
Score = 34.3 bits (77), Expect = 0.15
Identities = 20/85 (23%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V G+ +K+ I+ P P + W ++ ++ + DN L +KD ++D G
Sbjct: 19304 VKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDN--HTLLTVKDCIRRDTG 19361
Query: 236 WYTVSAVNEAGVTTCNTRLDVTARP 260
Y ++ N AG + V +P
Sbjct: 19362 QYVLTLKNVAGTRSVAVNCKVLDKP 19386
Score = 33.9 bits (76), Expect = 0.19
Identities = 39/137 (28%), Positives = 60/137 (43%), Gaps = 11/137 (8%)
Query: 178 EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD-AGW 236
EGD V L I+ ++ W N++V + L NT TL+I VN +D G
Sbjct: 4256 EGDIVHLTTSITNAK--EVNWYFENKLVPSDEKFKCLQDQNT--YTLVIDKVNTEDHQGE 4311
Query: 237 YTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGLNVKQAFNPE 296
Y A+N++G T + +L V R P K+ ++ P L ++ A P
Sbjct: 4312 YVCEALNDSGKTATSAKLTVVKR---AAPVIKR-KIEPLEVALGHLAKFTCEIQSA--PN 4365
Query: 297 GEFQRLAAQSGLYESEE 313
FQ A +YES++
Sbjct: 4366 VRFQWFKAGREIYESDK 4382
Score = 33.9 bits (76), Expect = 0.19
Identities = 22/94 (23%), Positives = 37/94 (39%), Gaps = 4/94 (4%)
Query: 172 QSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNK 231
Q+ V G S++L P P W + + + D TL +++ N+
Sbjct: 21868 QTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRAD----IHTTDSFSTLTVENCNR 21923
Query: 232 KDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLP 265
DAG YT++ N +G + + V P P
Sbjct: 21924 NDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGP 21957
Score = 33.5 bits (75), Expect = 0.25
Identities = 36/159 (22%), Positives = 62/159 (38%), Gaps = 16/159 (10%)
Query: 14 VFQAQDDSGAQDSQQHNSEHARLQVP------TSQVRSRSTSRGDVNDQDAIQEKFYPPR 67
V +A D+ + + N + R +V Q R + ++ +D + +K YP
Sbjct: 13130 VKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKD 13189
Query: 68 FIQVPEN---------MSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSE 118
+ PE + + G R+ V G P P ++W ++ D + I S
Sbjct: 13190 ILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLR-DRIGLDIKST 13248
Query: 119 KGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
L E V DAG Y +N G+ +T+ + VL
Sbjct: 13249 DFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVL 13287
Score = 33.1 bits (74), Expect = 0.33
Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V G +V+ I +P P W + ++ + + ++ DN V L IK+ ++D G
Sbjct: 11025 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTD-EHYTVETDNFSSV-LTIKNCLRRDTG 11082
Query: 236 WYTVSAVNEAGVTTCNTRLDVTARP 260
Y ++ N AG T L V P
Sbjct: 11083 EYQITVSNAAGSKTVAVHLTVLDVP 11107
Score = 33.1 bits (74), Expect = 0.33
Identities = 25/95 (26%), Positives = 39/95 (41%), Gaps = 1/95 (1%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP F + ++ G ++D G P P V+W+ + ++ +E
Sbjct: 15650 PPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLT 15709
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
I + R D G Y N AGEA T+ + VL K
Sbjct: 15710 IKDACR-EDVGHYVVKLTNSAGEAIETLNVIVLDK 15743
Score = 32.7 bits (73), Expect = 0.43
Identities = 26/104 (25%), Positives = 44/104 (42%), Gaps = 6/104 (5%)
Query: 59 IQEKFYPPRFI---QVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMI 115
++++ PP I + I G R+ + G+P P V+W R + ++
Sbjct: 10712 VKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTK--ARID 10769
Query: 116 VSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
V+ G L D G Y+ +N AG T +V++ VL K
Sbjct: 10770 VTPVG-SKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDK 10812
Score = 32.7 bits (73), Expect = 0.43
Identities = 22/95 (23%), Positives = 38/95 (40%), Gaps = 7/95 (7%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P + I VP GR + ++G P P SW+ G ++ + + + + L
Sbjct: 23247 PQKTIHVPA------GRPVELVIPIAGRPPPAASWFFAGSKLRESE-RVTVETHTKVAKL 23299
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAK 159
D G Y KN G + T+++ +L K
Sbjct: 23300 TIRETTIRDTGEYTLELKNVTGTTSETIKVIILDK 23334
Score = 32.0 bits (71), Expect = 0.73
Identities = 30/134 (22%), Positives = 44/134 (32%), Gaps = 9/134 (6%)
Query: 32 EHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYPP----RFIQVPENMSIDEGRFCRMDF 87
EH + V S + IQ+ PP R + + + G +
Sbjct: 8864 EHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPA 8923
Query: 88 KVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS-----LIFEVVRASDAGAYACVAK 142
V+GLP P + W N ++ I E+ S L D G Y A
Sbjct: 8924 DVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTAS 8983
Query: 143 NRAGEATFTVQLDV 156
NR G V ++V
Sbjct: 8984 NRLGSVFRNVHVEV 8997
Score = 32.0 bits (71), Expect = 0.73
Identities = 33/126 (26%), Positives = 58/126 (46%), Gaps = 8/126 (6%)
Query: 181 SVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIK-DVNKKDAGWYTV 239
+++L I P P++ W R++ + D+ S+ ++T TLLI +VN+ D+G Y +
Sbjct: 15380 TLRLFVPIKGRPAPEVKWARDHGE---SLDKASI--ESTSSYTLLIVGNVNRFDSGKYIL 15434
Query: 240 SAVNEAGVTTC--NTRLDVTARPNQTLPAPKQLRVRPTFSKYLALNGKGLNVKQAFNPEG 297
+ N +G + N R+ T P Q L + + T + L G +K +
Sbjct: 15435 TVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKR 15494
Query: 298 EFQRLA 303
E R A
Sbjct: 15495 ESTRKA 15500
Score = 31.6 bits (70), Expect = 0.96
Identities = 23/87 (26%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 89 VSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEA 148
+ G P P SW G+ ++ D+ I S L + DAG Y A N G
Sbjct: 13906 ILGKPLPKSSWSKAGKDIRPSDI-TQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTK 13964
Query: 149 TFTVQLDVLAKEHKRAPMFIYKPQSKK 175
V++ VL P+ I ++K
Sbjct: 13965 VEHVKVTVLDVPGPPGPVEISNVSAEK 13991
Score = 31.6 bits (70), Expect = 0.96
Identities = 26/109 (23%), Positives = 46/109 (42%), Gaps = 6/109 (5%)
Query: 52 DVNDQDAIQEKFYPPRF---IQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQS 108
DV ++EK P +++ + ++I G R+ + G P P+V W G+
Sbjct: 16429 DVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKW---GKVDGE 16485
Query: 109 DDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
+I SL+ + V D+G Y +N +G + V + VL
Sbjct: 16486 IRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVL 16534
Score = 31.6 bits (70), Expect = 0.96
Identities = 20/82 (24%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G V+L I+ PPP W ++ ++R+++ + +T L I++ +D G YT
Sbjct: 23256 GRPVELVIPIAGRPPPAASWFFAGSKLR-ESERVTV-ETHTKVAKLTIRETTIRDTGEYT 23313
Query: 239 VSAVNEAGVTTCNTRLDVTARP 260
+ N G T+ ++ + +P
Sbjct: 23314 LELKNVTGTTSETIKVIILDKP 23335
Score = 30.8 bits (68), Expect = 1.6
Identities = 23/87 (26%), Positives = 37/87 (42%), Gaps = 14/87 (16%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT-----LLIKDVNKKD 233
G +++ +S PPP + W N +L Q+ T T ++IK+ +
Sbjct: 10042 GGVIRIIAYVSGKPPPTVTWNMNER---------TLPQEATIETTAISSSMVIKNCQRSH 10092
Query: 234 AGWYTVSAVNEAGVTTCNTRLDVTARP 260
G Y++ A NEAG +DV P
Sbjct: 10093 QGVYSLLAKNEAGERKKTIIVDVLDVP 10119
Score = 30.4 bits (67), Expect = 2.1
Identities = 24/105 (22%), Positives = 43/105 (40%), Gaps = 13/105 (12%)
Query: 90 SGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEAT 149
+G P P +W + +++ D KM + L+ SD G Y +NR +
Sbjct: 6922 TGYPRPTATWCFGDKVLETGDRVKM-KTLSAYAELVISPSERSDKGIYTLKLENRVKTIS 6980
Query: 150 FTVQLDVLAKEHKRAPMFIYKPQSKKVLE-GDSVKLECQISAIPP 193
+ ++V+A +P + K L+ GD K ++ PP
Sbjct: 6981 GEIDVNVIA-----------RPSAPKELKFGDITKDSVHLTWEPP 7014
Score = 30.4 bits (67), Expect = 2.1
Identities = 25/113 (22%), Positives = 45/113 (39%), Gaps = 5/113 (4%)
Query: 47 STSRGDVNDQDAIQ--EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGR 104
S S G + +D I P++ V + + G ++ + G P PDV W +G+
Sbjct: 18193 SDSSGAITARDEIDAPNASLDPKYKDV---IVVHAGETFVLEADIRGKPIPDVVWSKDGK 18249
Query: 105 TVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
++ I S +L+ + +D G Y N G + + + VL
Sbjct: 18250 ELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVL 18302
Score = 30.0 bits (66), Expect = 2.8
Identities = 25/96 (26%), Positives = 48/96 (50%), Gaps = 7/96 (7%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLL-IKDVNKKDAGWY 237
G+ V++ PPP + W+++ + + + R S+ +NT +LL I V + D G Y
Sbjct: 20789 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSDA-RYSI--ENTDSSSLLTIPQVTRNDTGKY 20845
Query: 238 TVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVR 273
++ N G +T V+ + T A ++L+V+
Sbjct: 20846 ILTIENGVGEPKSST---VSVKVLDTPAACQKLQVK 20878
Score = 30.0 bits (66), Expect = 2.8
Identities = 16/61 (26%), Positives = 26/61 (42%), Gaps = 2/61 (3%)
Query: 179 GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
G +V LE P P + W ++ + + ++TL IK+ K+ G YT
Sbjct: 21081 GHNVHLELPYKGKPKPSISWLKDG--LPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT 21138
Query: 239 V 239
V
Sbjct: 21139 V 21139
Score = 29.6 bits (65), Expect = 3.6
Identities = 24/102 (23%), Positives = 42/102 (41%), Gaps = 8/102 (7%)
Query: 60 QEKFYPPRFIQVPENMSIDEGRFC---RMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIV 116
+++ PP + + R C R+ + G PAP+V W + + L K +
Sbjct: 15355 EDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARD----HGESLDKASI 15410
Query: 117 SEKGLHS-LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVL 157
++ LI V D+G Y +N +G + V + VL
Sbjct: 15411 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVL 15452
Score = 29.6 bits (65), Expect = 3.6
Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 3/84 (3%)
Query: 75 MSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL-IFEVVRASD 133
++I G +D V G P P + W + + D K+ + G + + + SD
Sbjct: 22560 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKEL--DLCEKVSLQYTGKRATAVIKFCDRSD 22617
Query: 134 AGAYACVAKNRAGEATFTVQLDVL 157
+G Y KN +G +V + VL
Sbjct: 22618 SGKYTLTVKNASGTKAVSVMVKVL 22641
Score = 29.3 bits (64), Expect = 4.7
Identities = 18/86 (20%), Positives = 37/86 (43%), Gaps = 4/86 (4%)
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V +G ++L I P P W + + + + ++ + L+IK+ ++ D+G
Sbjct: 23651 VRQGGVIRLTIPIKGKPFPICKWTKEGQDIS----KRAMIATSETHTELVIKEADRGDSG 23706
Query: 236 WYTVSAVNEAGVTTCNTRLDVTARPN 261
Y + N+ G ++ V PN
Sbjct: 23707 TYDLVLENKCGKKAVYIKVRVIGSPN 23732
Score = 28.9 bits (63), Expect = 6.2
Identities = 33/112 (29%), Positives = 44/112 (39%), Gaps = 26/112 (23%)
Query: 89 VSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI----FEVVRAS---DAGAYACVA 141
V G PAP V+W R V D+ V KG L+ F V+ S D+G Y+
Sbjct: 12133 VRGRPAPKVTW----RKVGIDN-----VVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTL 12183
Query: 142 KNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPP 193
N AGE V + VL + + + D K C +S PP
Sbjct: 12184 VNPAGEKAVFVNVRVLDTPGPVSDLKV----------SDVTKTSCHVSWAPP 12225
Score = 28.5 bits (62), Expect = 8.1
Identities = 26/125 (20%), Positives = 48/125 (38%), Gaps = 6/125 (4%)
Query: 35 RLQVPTSQVRSRSTSRGDVNDQDAIQ--EKFYPPRFIQVPENMSIDEGRFCRMDFKVSGL 92
RLQ+ + R + R D++A E P+ +++ +D G+ M
Sbjct: 6470 RLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAY 6529
Query: 93 PAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTV 152
P + W+ + + K I + S + D G Y V +N+ G+A +
Sbjct: 6530 PKAEAEWFKENEPLST----KTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFI 6585
Query: 153 QLDVL 157
L V+
Sbjct: 6586 NLKVI 6590
Score = 28.5 bits (62), Expect = 8.1
Identities = 19/73 (26%), Positives = 31/73 (42%), Gaps = 1/73 (1%)
Query: 84 RMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKN 143
+++ V G P P V+W + ++ + I E VR SD+G Y A+N
Sbjct: 14587 KVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVR-SDSGPYPLTARN 14645
Query: 144 RAGEATFTVQLDV 156
GE + + V
Sbjct: 14646 IVGEVGDVITIQV 14658
>gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]
Length = 1863
Score = 95.1 bits (235), Expect = 7e-20
Identities = 65/206 (31%), Positives = 94/206 (45%), Gaps = 6/206 (2%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ-SDDLHKMIVSEKGL-HS 123
P F+Q ++ + +G M +VSG P P+V W NG +Q S+D H ++G HS
Sbjct: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH---FEQRGTQHS 679
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
L + V D G Y C A N AGE L V P FI KP+S G SV
Sbjct: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
+ C I+ P P + W R+ + + +T + Q N TL++K V AG Y + N
Sbjct: 740 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ-NEDVFTLVLKKVQPWHAGQYEILLKN 798
Query: 244 EAGVTTCNTRLDVTARPNQTLPAPKQ 269
G +C L + + LP ++
Sbjct: 799 RVGECSCQVSLMLQNSSARALPRGRE 824
Score = 94.7 bits (234), Expect = 9e-20
Identities = 69/261 (26%), Positives = 119/261 (45%), Gaps = 19/261 (7%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P+F P++ + E + + +VSG+P P+V+W+L G V+ + + + G H L
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
Query: 126 FEVVRASDAGAYACVAKNRAGE--ATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
R D+G Y+C A N G+ ++T+Q++ LA + AP F + V+EG
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLA-VMEVAPSFSSVLKDCAVIEGQDFV 532
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
L+C + P P++ W N + +Q+ G L I+D +D G YT A N
Sbjct: 533 LQCSVRGTPVPRITWLLNGQPIQYARSTC-----EAGVAELHIQDALPEDHGTYTCLAEN 587
Query: 244 EAGVTTCNTRLDV-----TARPNQTLPAPKQLRVRPTFSKYLA----LNGK--GLNVKQA 292
G +C+ + V + + LP P F + L+ ++G + V+ +
Sbjct: 588 ALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 647
Query: 293 FNPEGEFQRLAAQSGLYESEE 313
NP E L + + ESE+
Sbjct: 648 GNPPPEVIWLHNGNEIQESED 668
Score = 88.2 bits (217), Expect = 9e-18
Identities = 62/220 (28%), Positives = 92/220 (41%), Gaps = 31/220 (14%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P FI P N+ I EG + + +V G P P V+W+ NG+ + S + +G SL+
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKR---------------------- 163
V D G Y C A N +G TV+L V K+
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
Query: 164 -------APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQ 216
P F K V EG + C+I+ P P++ W + N +Q + R+S+ +
Sbjct: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ-PSARVSVSE 211
Query: 217 DNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
N G L I VN+ D G YT VN +G + + L +
Sbjct: 212 KN-GMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 69.3 bits (168), Expect = 4e-12
Identities = 61/270 (22%), Positives = 111/270 (41%), Gaps = 47/270 (17%)
Query: 41 SQVRSRSTSRGDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWY 100
+ V + G +++ + + P F Q +++ + EG+ + +VS P + W
Sbjct: 1073 NDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWT 1132
Query: 101 LNGRTVQSDDLHKMIVSEKG-LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQL---DV 156
LNG+T+++ +I+S++G L S+ E D G Y CVAKN AG+A + Q+ D
Sbjct: 1133 LNGKTLKTTKF--IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1190
Query: 157 LAKEHKRA---------------------------------------PMFIYKPQSKKVL 177
A E+ +A P I P+ +KV
Sbjct: 1191 PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1250
Query: 178 EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
G+SV+L +++ P W + + +Q + +N ++T+L ++ G Y
Sbjct: 1251 AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILA--ARQEHCGCY 1308
Query: 238 TVSAVNEAGVTTCNTRLDVTARPNQTLPAP 267
T+ N+ G L V +P+ P
Sbjct: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
Score = 56.6 bits (135), Expect = 3e-08
Identities = 39/127 (30%), Positives = 60/127 (47%), Gaps = 5/127 (3%)
Query: 39 PTSQVRSRST-SRGDVNDQ--DAIQEK--FYPPRFIQVPENMSIDEGRFCRMDFKVSGLP 93
PTS + + S DV+ +A+ E+ P F + ++ + EG R D K+ G P
Sbjct: 1726 PTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYP 1785
Query: 94 APDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQ 153
P+V W+ + ++++ ++ E G SLI V D Y C A N GEAT T +
Sbjct: 1786 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 1845
Query: 154 LDVLAKE 160
L V E
Sbjct: 1846 LIVETME 1852
Score = 54.7 bits (130), Expect = 1e-07
Identities = 30/104 (28%), Positives = 52/104 (50%), Gaps = 2/104 (1%)
Query: 154 LDVLAKEHKRA-PMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRI 212
L+ +A+E P F + +V+EG + + +C+I P P++ W ++++ ++ +
Sbjct: 1746 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR-ESRHF 1804
Query: 213 SLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
+ D G +L+I DV D YT AVN G TC L V
Sbjct: 1805 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
Score = 52.8 bits (125), Expect = 4e-07
Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 3/115 (2%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP F K Q V EG + L+CQ+S+ PP + W N + ++ T + + +
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK--TTKFIILSQEGSLCS 1154
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARP-NQTLPAPKQLRVRPTFS 277
+ I+ +D G Y A N+AG C+ ++ V P ++ AP+ RP S
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSS 1209
Score = 50.8 bits (120), Expect = 2e-06
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP+F + + EG+ R K++G P P V+W L G + + G+ L
Sbjct: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW-LKGNVPLQPSARVSVSEKNGMQVL 218
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDV 156
V D G Y C+ N +G+A+ + +L +
Sbjct: 219 EIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 49.3 bits (116), Expect = 4e-06
Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP FI P++ + EG + K E ++ P P++ W RN + + + R L G +
Sbjct: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT-SGGRFLLDCGIRGTFS 90
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
L+I V+++D G YT A N +G L V
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
>gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]
Length = 1914
Score = 95.1 bits (235), Expect = 7e-20
Identities = 65/206 (31%), Positives = 94/206 (45%), Gaps = 6/206 (2%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ-SDDLHKMIVSEKGL-HS 123
P F+Q ++ + +G M +VSG P P+V W NG +Q S+D H ++G HS
Sbjct: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH---FEQRGTQHS 679
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
L + V D G Y C A N AGE L V P FI KP+S G SV
Sbjct: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
+ C I+ P P + W R+ + + +T + Q N TL++K V AG Y + N
Sbjct: 740 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ-NEDVFTLVLKKVQPWHAGQYEILLKN 798
Query: 244 EAGVTTCNTRLDVTARPNQTLPAPKQ 269
G +C L + + LP ++
Sbjct: 799 RVGECSCQVSLMLQNSSARALPRGRE 824
Score = 94.7 bits (234), Expect = 9e-20
Identities = 69/261 (26%), Positives = 119/261 (45%), Gaps = 19/261 (7%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P+F P++ + E + + +VSG+P P+V+W+L G V+ + + + G H L
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
Query: 126 FEVVRASDAGAYACVAKNRAGE--ATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
R D+G Y+C A N G+ ++T+Q++ LA + AP F + V+EG
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLA-VMEVAPSFSSVLKDCAVIEGQDFV 532
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
L+C + P P++ W N + +Q+ G L I+D +D G YT A N
Sbjct: 533 LQCSVRGTPVPRITWLLNGQPIQYARSTC-----EAGVAELHIQDALPEDHGTYTCLAEN 587
Query: 244 EAGVTTCNTRLDV-----TARPNQTLPAPKQLRVRPTFSKYLA----LNGK--GLNVKQA 292
G +C+ + V + + LP P F + L+ ++G + V+ +
Sbjct: 588 ALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 647
Query: 293 FNPEGEFQRLAAQSGLYESEE 313
NP E L + + ESE+
Sbjct: 648 GNPPPEVIWLHNGNEIQESED 668
Score = 88.2 bits (217), Expect = 9e-18
Identities = 62/220 (28%), Positives = 92/220 (41%), Gaps = 31/220 (14%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P FI P N+ I EG + + +V G P P V+W+ NG+ + S + +G SL+
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKR---------------------- 163
V D G Y C A N +G TV+L V K+
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
Query: 164 -------APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQ 216
P F K V EG + C+I+ P P++ W + N +Q + R+S+ +
Sbjct: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ-PSARVSVSE 211
Query: 217 DNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
N G L I VN+ D G YT VN +G + + L +
Sbjct: 212 KN-GMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 69.3 bits (168), Expect = 4e-12
Identities = 61/270 (22%), Positives = 111/270 (41%), Gaps = 47/270 (17%)
Query: 41 SQVRSRSTSRGDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWY 100
+ V + G +++ + + P F Q +++ + EG+ + +VS P + W
Sbjct: 1073 NDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWT 1132
Query: 101 LNGRTVQSDDLHKMIVSEKG-LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQL---DV 156
LNG+T+++ +I+S++G L S+ E D G Y CVAKN AG+A + Q+ D
Sbjct: 1133 LNGKTLKTTKF--IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1190
Query: 157 LAKEHKRA---------------------------------------PMFIYKPQSKKVL 177
A E+ +A P I P+ +KV
Sbjct: 1191 PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1250
Query: 178 EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
G+SV+L +++ P W + + +Q + +N ++T+L ++ G Y
Sbjct: 1251 AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILA--ARQEHCGCY 1308
Query: 238 TVSAVNEAGVTTCNTRLDVTARPNQTLPAP 267
T+ N+ G L V +P+ P
Sbjct: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
Score = 56.6 bits (135), Expect = 3e-08
Identities = 39/127 (30%), Positives = 60/127 (47%), Gaps = 5/127 (3%)
Query: 39 PTSQVRSRST-SRGDVNDQ--DAIQEK--FYPPRFIQVPENMSIDEGRFCRMDFKVSGLP 93
PTS + + S DV+ +A+ E+ P F + ++ + EG R D K+ G P
Sbjct: 1777 PTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYP 1836
Query: 94 APDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQ 153
P+V W+ + ++++ ++ E G SLI V D Y C A N GEAT T +
Sbjct: 1837 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 1896
Query: 154 LDVLAKE 160
L V E
Sbjct: 1897 LIVETME 1903
Score = 54.7 bits (130), Expect = 1e-07
Identities = 30/104 (28%), Positives = 52/104 (50%), Gaps = 2/104 (1%)
Query: 154 LDVLAKEHKRA-PMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRI 212
L+ +A+E P F + +V+EG + + +C+I P P++ W ++++ ++ +
Sbjct: 1797 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR-ESRHF 1855
Query: 213 SLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
+ D G +L+I DV D YT AVN G TC L V
Sbjct: 1856 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899
Score = 52.8 bits (125), Expect = 4e-07
Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 3/115 (2%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP F K Q V EG + L+CQ+S+ PP + W N + ++ T + + +
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK--TTKFIILSQEGSLCS 1154
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARP-NQTLPAPKQLRVRPTFS 277
+ I+ +D G Y A N+AG C+ ++ V P ++ AP+ RP S
Sbjct: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSS 1209
Score = 50.8 bits (120), Expect = 2e-06
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP+F + + EG+ R K++G P P V+W L G + + G+ L
Sbjct: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW-LKGNVPLQPSARVSVSEKNGMQVL 218
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDV 156
V D G Y C+ N +G+A+ + +L +
Sbjct: 219 EIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 49.3 bits (116), Expect = 4e-06
Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP FI P++ + EG + K E ++ P P++ W RN + + + R L G +
Sbjct: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT-SGGRFLLDCGIRGTFS 90
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
L+I V+++D G YT A N +G L V
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
>gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens]
Length = 1794
Score = 95.1 bits (235), Expect = 7e-20
Identities = 65/206 (31%), Positives = 94/206 (45%), Gaps = 6/206 (2%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ-SDDLHKMIVSEKGL-HS 123
P F+Q ++ + +G M +VSG P P+V W NG +Q S+D H ++G HS
Sbjct: 554 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH---FEQRGTQHS 610
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
L + V D G Y C A N AGE L V P FI KP+S G SV
Sbjct: 611 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 670
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
+ C I+ P P + W R+ + + +T + Q N TL++K V AG Y + N
Sbjct: 671 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ-NEDVFTLVLKKVQPWHAGQYEILLKN 729
Query: 244 EAGVTTCNTRLDVTARPNQTLPAPKQ 269
G +C L + + LP ++
Sbjct: 730 RVGECSCQVSLMLQNSSARALPRGRE 755
Score = 88.2 bits (217), Expect = 9e-18
Identities = 62/220 (28%), Positives = 92/220 (41%), Gaps = 31/220 (14%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P FI P N+ I EG + + +V G P P V+W+ NG+ + S + +G SL+
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKR---------------------- 163
V D G Y C A N +G TV+L V K+
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
Query: 164 -------APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQ 216
P F K V EG + C+I+ P P++ W + N +Q + R+S+ +
Sbjct: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ-PSARVSVSE 211
Query: 217 DNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
N G L I VN+ D G YT VN +G + + L +
Sbjct: 212 KN-GMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 87.0 bits (214), Expect = 2e-17
Identities = 58/214 (27%), Positives = 96/214 (44%), Gaps = 20/214 (9%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F V ++ ++ EG+ + V G P P ++W LNG+ +Q + E G+ L
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ----YARSTCEAGVAELH 500
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKR--------------APMFIYKP 171
+ D G Y C+A+N G+ + + + V K+ R AP+F+
Sbjct: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL 560
Query: 172 QSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNK 231
KV++G V + Q+S PPP++ W N +Q + D ++ + +L I++V
Sbjct: 561 SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED--FHFEQRGTQHSLCIQEVFP 618
Query: 232 KDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLP 265
+D G YT A N AG L V + T P
Sbjct: 619 EDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQP 652
Score = 69.3 bits (168), Expect = 4e-12
Identities = 61/270 (22%), Positives = 111/270 (41%), Gaps = 47/270 (17%)
Query: 41 SQVRSRSTSRGDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWY 100
+ V + G +++ + + P F Q +++ + EG+ + +VS P + W
Sbjct: 1004 NDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWT 1063
Query: 101 LNGRTVQSDDLHKMIVSEKG-LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQL---DV 156
LNG+T+++ +I+S++G L S+ E D G Y CVAKN AG+A + Q+ D
Sbjct: 1064 LNGKTLKTTKF--IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1121
Query: 157 LAKEHKRA---------------------------------------PMFIYKPQSKKVL 177
A E+ +A P I P+ +KV
Sbjct: 1122 PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1181
Query: 178 EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
G+SV+L +++ P W + + +Q + +N ++T+L ++ G Y
Sbjct: 1182 AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILA--ARQEHCGCY 1239
Query: 238 TVSAVNEAGVTTCNTRLDVTARPNQTLPAP 267
T+ N+ G L V +P+ P
Sbjct: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1269
Score = 56.6 bits (135), Expect = 3e-08
Identities = 39/127 (30%), Positives = 60/127 (47%), Gaps = 5/127 (3%)
Query: 39 PTSQVRSRST-SRGDVNDQ--DAIQEK--FYPPRFIQVPENMSIDEGRFCRMDFKVSGLP 93
PTS + + S DV+ +A+ E+ P F + ++ + EG R D K+ G P
Sbjct: 1657 PTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYP 1716
Query: 94 APDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQ 153
P+V W+ + ++++ ++ E G SLI V D Y C A N GEAT T +
Sbjct: 1717 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 1776
Query: 154 LDVLAKE 160
L V E
Sbjct: 1777 LIVETME 1783
Score = 54.7 bits (130), Expect = 1e-07
Identities = 30/104 (28%), Positives = 52/104 (50%), Gaps = 2/104 (1%)
Query: 154 LDVLAKEHKRA-PMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRI 212
L+ +A+E P F + +V+EG + + +C+I P P++ W ++++ ++ +
Sbjct: 1677 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR-ESRHF 1735
Query: 213 SLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
+ D G +L+I DV D YT AVN G TC L V
Sbjct: 1736 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
Score = 52.8 bits (125), Expect = 4e-07
Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 3/115 (2%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP F K Q V EG + L+CQ+S+ PP + W N + ++ T + + +
Sbjct: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK--TTKFIILSQEGSLCS 1085
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARP-NQTLPAPKQLRVRPTFS 277
+ I+ +D G Y A N+AG C+ ++ V P ++ AP+ RP S
Sbjct: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSS 1140
Score = 50.8 bits (120), Expect = 2e-06
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP+F + + EG+ R K++G P P V+W L G + + G+ L
Sbjct: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW-LKGNVPLQPSARVSVSEKNGMQVL 218
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDV 156
V D G Y C+ N +G+A+ + +L +
Sbjct: 219 EIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 49.3 bits (116), Expect = 4e-06
Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP FI P++ + EG + K E ++ P P++ W RN + + + R L G +
Sbjct: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT-SGGRFLLDCGIRGTFS 90
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
L+I V+++D G YT A N +G L V
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 45.1 bits (105), Expect = 8e-05
Identities = 40/161 (24%), Positives = 66/161 (40%), Gaps = 16/161 (9%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP F + V+EG L+C + P P++ W N + +Q+ G
Sbjct: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC-----EAGVAE 498
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV-----TARPNQTLPAPKQLRVRPTFSK 278
L I+D +D G YT A N G +C+ + V + + LP P F +
Sbjct: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 558
Query: 279 YLA----LNGK--GLNVKQAFNPEGEFQRLAAQSGLYESEE 313
L+ ++G + V+ + NP E L + + ESE+
Sbjct: 559 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 599
>gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens]
Length = 1845
Score = 95.1 bits (235), Expect = 7e-20
Identities = 65/206 (31%), Positives = 94/206 (45%), Gaps = 6/206 (2%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ-SDDLHKMIVSEKGL-HS 123
P F+Q ++ + +G M +VSG P P+V W NG +Q S+D H ++G HS
Sbjct: 554 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH---FEQRGTQHS 610
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
L + V D G Y C A N AGE L V P FI KP+S G SV
Sbjct: 611 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 670
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
+ C I+ P P + W R+ + + +T + Q N TL++K V AG Y + N
Sbjct: 671 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ-NEDVFTLVLKKVQPWHAGQYEILLKN 729
Query: 244 EAGVTTCNTRLDVTARPNQTLPAPKQ 269
G +C L + + LP ++
Sbjct: 730 RVGECSCQVSLMLQNSSARALPRGRE 755
Score = 88.2 bits (217), Expect = 9e-18
Identities = 62/220 (28%), Positives = 92/220 (41%), Gaps = 31/220 (14%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P FI P N+ I EG + + +V G P P V+W+ NG+ + S + +G SL+
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKR---------------------- 163
V D G Y C A N +G TV+L V K+
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
Query: 164 -------APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQ 216
P F K V EG + C+I+ P P++ W + N +Q + R+S+ +
Sbjct: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ-PSARVSVSE 211
Query: 217 DNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
N G L I VN+ D G YT VN +G + + L +
Sbjct: 212 KN-GMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 87.0 bits (214), Expect = 2e-17
Identities = 58/214 (27%), Positives = 96/214 (44%), Gaps = 20/214 (9%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F V ++ ++ EG+ + V G P P ++W LNG+ +Q + E G+ L
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ----YARSTCEAGVAELH 500
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKR--------------APMFIYKP 171
+ D G Y C+A+N G+ + + + V K+ R AP+F+
Sbjct: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL 560
Query: 172 QSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNK 231
KV++G V + Q+S PPP++ W N +Q + D ++ + +L I++V
Sbjct: 561 SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED--FHFEQRGTQHSLCIQEVFP 618
Query: 232 KDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLP 265
+D G YT A N AG L V + T P
Sbjct: 619 EDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQP 652
Score = 69.3 bits (168), Expect = 4e-12
Identities = 61/270 (22%), Positives = 111/270 (41%), Gaps = 47/270 (17%)
Query: 41 SQVRSRSTSRGDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWY 100
+ V + G +++ + + P F Q +++ + EG+ + +VS P + W
Sbjct: 1004 NDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWT 1063
Query: 101 LNGRTVQSDDLHKMIVSEKG-LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQL---DV 156
LNG+T+++ +I+S++G L S+ E D G Y CVAKN AG+A + Q+ D
Sbjct: 1064 LNGKTLKTTKF--IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1121
Query: 157 LAKEHKRA---------------------------------------PMFIYKPQSKKVL 177
A E+ +A P I P+ +KV
Sbjct: 1122 PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1181
Query: 178 EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
G+SV+L +++ P W + + +Q + +N ++T+L ++ G Y
Sbjct: 1182 AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILA--ARQEHCGCY 1239
Query: 238 TVSAVNEAGVTTCNTRLDVTARPNQTLPAP 267
T+ N+ G L V +P+ P
Sbjct: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1269
Score = 56.6 bits (135), Expect = 3e-08
Identities = 39/127 (30%), Positives = 60/127 (47%), Gaps = 5/127 (3%)
Query: 39 PTSQVRSRST-SRGDVNDQ--DAIQEK--FYPPRFIQVPENMSIDEGRFCRMDFKVSGLP 93
PTS + + S DV+ +A+ E+ P F + ++ + EG R D K+ G P
Sbjct: 1708 PTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYP 1767
Query: 94 APDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQ 153
P+V W+ + ++++ ++ E G SLI V D Y C A N GEAT T +
Sbjct: 1768 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 1827
Query: 154 LDVLAKE 160
L V E
Sbjct: 1828 LIVETME 1834
Score = 54.7 bits (130), Expect = 1e-07
Identities = 30/104 (28%), Positives = 52/104 (50%), Gaps = 2/104 (1%)
Query: 154 LDVLAKEHKRA-PMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRI 212
L+ +A+E P F + +V+EG + + +C+I P P++ W ++++ ++ +
Sbjct: 1728 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR-ESRHF 1786
Query: 213 SLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
+ D G +L+I DV D YT AVN G TC L V
Sbjct: 1787 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1830
Score = 52.8 bits (125), Expect = 4e-07
Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 3/115 (2%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP F K Q V EG + L+CQ+S+ PP + W N + ++ T + + +
Sbjct: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK--TTKFIILSQEGSLCS 1085
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARP-NQTLPAPKQLRVRPTFS 277
+ I+ +D G Y A N+AG C+ ++ V P ++ AP+ RP S
Sbjct: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSS 1140
Score = 50.8 bits (120), Expect = 2e-06
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP+F + + EG+ R K++G P P V+W L G + + G+ L
Sbjct: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW-LKGNVPLQPSARVSVSEKNGMQVL 218
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDV 156
V D G Y C+ N +G+A+ + +L +
Sbjct: 219 EIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 49.3 bits (116), Expect = 4e-06
Identities = 29/93 (31%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP FI P++ + EG + K E ++ P P++ W RN + + + R L G +
Sbjct: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT-SGGRFLLDCGIRGTFS 90
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
L+I V+++D G YT A N +G L V
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 45.1 bits (105), Expect = 8e-05
Identities = 40/161 (24%), Positives = 66/161 (40%), Gaps = 16/161 (9%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP F + V+EG L+C + P P++ W N + +Q+ G
Sbjct: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC-----EAGVAE 498
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV-----TARPNQTLPAPKQLRVRPTFSK 278
L I+D +D G YT A N G +C+ + V + + LP P F +
Sbjct: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 558
Query: 279 YLA----LNGK--GLNVKQAFNPEGEFQRLAAQSGLYESEE 313
L+ ++G + V+ + NP E L + + ESE+
Sbjct: 559 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 599
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 91.3 bits (225), Expect = 1e-18
Identities = 60/244 (24%), Positives = 110/244 (45%), Gaps = 8/244 (3%)
Query: 16 QAQDDSGAQDSQQHNSEHAR---LQVPTSQVRSRSTSRGDVNDQDAIQEKFYPPRFIQVP 72
Q + D A + Q + R LQ T+ ++S Q + PP F +
Sbjct: 5961 QVEGDDRAFEVWQEREDSVRKYLLQARTAIIKSSWVKEICGIQQRLALPVWRPPDFEEEL 6020
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 132
+ + + G ++ +V+G P P +SWY +G+ VQ D H +I G +LI + +
Sbjct: 6021 ADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGV 6080
Query: 133 DAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIP 192
D+G Y C A + AG + ++ V + P F+ K ++ +EG+ + C I P
Sbjct: 6081 DSGQYMCFAASAAGNCSTLGKILV-----QVPPRFVNKVRASPFVEGEDAQFTCTIEGAP 6135
Query: 193 PPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
P++ W ++ ++ +L + +G + L+I+ +K+D G Y VN G +
Sbjct: 6136 YPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASA 6195
Query: 253 RLDV 256
L +
Sbjct: 6196 ELRI 6199
Score = 78.2 bits (191), Expect = 9e-15
Identities = 54/205 (26%), Positives = 90/205 (43%), Gaps = 5/205 (2%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
PRF+ P+ + G+ + ++ G P P VSW + + V + ++ + L+ L
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRL-AQDGDLYRLT 68
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTV--QLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
+ D+G Y C A+N GEA V Q+D A ++AP F+ +P S +V EG
Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEAT 128
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLL-IKDVNKKDAGWYTVSAV 242
C++ P P + W ++ + D + + G + L I+ +D G Y V A
Sbjct: 129 FRCRVGGSPRPAVSWSKDGRRLG-EPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAE 187
Query: 243 NEAGVTTCNTRLDVTARPNQTLPAP 267
N G + L V + T P
Sbjct: 188 NPLGAASAAAALVVDSDAADTASRP 212
Score = 67.0 bits (162), Expect = 2e-11
Identities = 54/212 (25%), Positives = 91/212 (42%), Gaps = 18/212 (8%)
Query: 66 PRFIQVPENMSIDEG-RFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P+ ++ ++ + G R + KV G PAP + W+ +G+ + + H + +K LH+L
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTA-SAHIRMTDKKILHTL 5318
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLA---KEHKRA---------PMFIYKPQ 172
V D+G YA N G A + +L V E K A P + +
Sbjct: 5319 EIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFT 5378
Query: 173 SKKVLEGDSVKLECQISAIPPPKLFWKRNNE---MVQFNTDRIS-LYQDNTGRVTLLIKD 228
KKV +G S+ ++ P P + W R ++ D + + +L++ D
Sbjct: 5379 PKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLD 5438
Query: 229 VNKKDAGWYTVSAVNEAGVTTCNTRLDVTARP 260
V ++ G YT A N AG C+ L V+ P
Sbjct: 5439 VGRQHQGTYTCIASNAAGQALCSASLHVSGLP 5470
Score = 65.9 bits (159), Expect = 5e-11
Identities = 51/230 (22%), Positives = 96/230 (41%), Gaps = 48/230 (20%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F+ +N + +G D V+G P P V W+ +G+ ++ DD + + ++G H LI
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQL--DVLAKEHKRA------------------- 164
V +D G Y C+A+N G ++ +L D+ + ++ A
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSSR 5245
Query: 165 --------------PMFIYKPQSKKVLEGDSV-KLECQISAIPPPKLFWKRNNEMVQFN- 208
P + + + +V G + K + ++ P P+L+W ++ + + +
Sbjct: 5246 EQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASA 5305
Query: 209 ----TDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRL 254
TD+ L+ TL I V ++D+G Y N G + RL
Sbjct: 5306 HIRMTDKKILH-------TLEIISVTREDSGQYAAYISNAMGAAYSSARL 5348
Score = 64.7 bits (156), Expect = 1e-10
Identities = 56/212 (26%), Positives = 83/212 (39%), Gaps = 30/212 (14%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F+ P ++ + EG +V G P P VSW +GR + D ++ V E G S +
Sbjct: 110 PHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASAL 169
Query: 126 -FEVVRASDAGAYACVAKNRAGEATFTVQLDVLA-----------------------KEH 161
R D G Y A+N G A+ L V + +E
Sbjct: 170 RIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREA 229
Query: 162 KRAPMFIYKPQSK-----KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQ 216
RA P S V EG +L C ++ P P+ WK++ ++V + +Y+
Sbjct: 230 MRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHV-VYE 288
Query: 217 DNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVT 248
D L I + D G YT +A N G T
Sbjct: 289 DAQENFVLKILFCKQSDRGLYTCTASNLVGQT 320
Score = 53.5 bits (127), Expect = 2e-07
Identities = 55/204 (26%), Positives = 85/204 (41%), Gaps = 17/204 (8%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P +FI+ N EG + ++S A V W T++ D H + + L
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCELS--KAAPVEWRKGHETLRDGDRHSLR-QDGSRCEL 3769
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
+ DAG Y+CV AT TV+ FI ++++ EG + L
Sbjct: 3770 QIRGLAVVDAGEYSCVCGQERTSATLTVR--------ALPARFIEDVKNQEAREGATAVL 3821
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
+C++S P + W++ +E ++ DR SL QD T R L I ++ D G Y+ E
Sbjct: 3822 QCELSKAAPVE--WRKGSETLR-GGDRYSLRQDGT-RCELQIHGLSVADTGEYSCVCGQE 3877
Query: 245 AGVTTCNTRL--DVTARPNQTLPA 266
T R V P Q+L A
Sbjct: 3878 RTSATLTVRAPQPVFREPLQSLQA 3901
Score = 52.4 bits (124), Expect = 5e-07
Identities = 44/187 (23%), Positives = 82/187 (43%), Gaps = 12/187 (6%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 132
+++ + EG+ ++S + W L G +Q+++++ + V + LH L V
Sbjct: 4257 QDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLE 4316
Query: 133 DAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIP 192
DAG + G + QL V AK + ++ + LEG ECQ+S
Sbjct: 4317 DAGTVSF----HVGTCSSEAQLKVTAKN-----TVVRGLENVEALEGGEALFECQLSQPE 4367
Query: 193 PPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSA---VNEAGVTT 249
W ++E V + + ++ +N R LL+K++ +D+ T A V A +T
Sbjct: 4368 VAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLAGDMVTSAFLTV 4427
Query: 250 CNTRLDV 256
RL++
Sbjct: 4428 RGWRLEI 4434
Score = 50.1 bits (118), Expect = 3e-06
Identities = 53/189 (28%), Positives = 85/189 (44%), Gaps = 15/189 (7%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P +F + N EG + ++S + AP V W+ T++ D H +
Sbjct: 3625 PIKFTEGLRNEEATEGATAVLRCELSKM-AP-VEWWKGHETLRDGDRHSLRQDGARCELQ 3682
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
I +V A DAG Y C+ G+ + L V A K FI ++++ EGD+ L
Sbjct: 3683 IRGLV-AEDAGEYLCM----CGKERTSAMLTVRAMPSK----FIEGLRNEEATEGDTATL 3733
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
C++S P + W++ +E ++ + DR SL QD + R L I+ + DAG Y+ E
Sbjct: 3734 WCELSKAAPVE--WRKGHETLR-DGDRHSLRQDGS-RCELQIRGLAVVDAGEYSCVCGQE 3789
Query: 245 AGVTTCNTR 253
T R
Sbjct: 3790 RTSATLTVR 3798
Score = 48.1 bits (113), Expect = 1e-05
Identities = 53/213 (24%), Positives = 92/213 (43%), Gaps = 19/213 (8%)
Query: 51 GDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD 110
GD A++ P F + + +I EG + + S P V W +G+T++
Sbjct: 3081 GDQRASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSA 3139
Query: 111 LHKMIVSEKGLHS-LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIY 169
+ +S +G + L+ D+G Y C A + + + H R F
Sbjct: 3140 --RCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSS--------IVRVHARPVRFQE 3189
Query: 170 KPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDV 229
+ +VLEG + L C +S++ P + NN V D+ SL Q+ + L+++++
Sbjct: 3190 ALKDLEVLEGGAATLRCVLSSVAAPVKWCYGNN--VLRPGDKYSLRQEG-AMLELVVRNL 3246
Query: 230 NKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQ 262
+D+G Y+ S G T + L VTA P Q
Sbjct: 3247 RPQDSGRYSCS----FGDQTTSATLTVTALPAQ 3275
Score = 48.1 bits (113), Expect = 1e-05
Identities = 49/174 (28%), Positives = 76/174 (43%), Gaps = 17/174 (9%)
Query: 88 KVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGE 147
+VS A V W L G +QS+++ ++ V + +H+L + V DAG + N A
Sbjct: 4181 EVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASS 4240
Query: 148 ATFTVQLDVLAKEHKRAP-MFIYKP-QSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMV 205
A TV RAP + I +P Q ++ EG +C++S + W +
Sbjct: 4241 AQLTV----------RAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPL 4290
Query: 206 QFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 259
Q N + T + L K V +DAG TVS G + +L VTA+
Sbjct: 4291 QANEMNDITVEQGTLHLLTLHK-VTLEDAG--TVSF--HVGTCSSEAQLKVTAK 4339
Score = 48.1 bits (113), Expect = 1e-05
Identities = 29/102 (28%), Positives = 52/102 (50%), Gaps = 3/102 (2%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP+F+ + Q+++V +G V +C ++ P P + W ++ ++++ D + +D G
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLE-EDDHYMINEDQQGGHQ 5183
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGV--TTCNTRLDVTARPNQT 263
L+I V D G Y A N GV T R+D+T+ T
Sbjct: 5184 LIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDT 5225
Score = 47.8 bits (112), Expect = 1e-05
Identities = 37/150 (24%), Positives = 73/150 (48%), Gaps = 14/150 (9%)
Query: 96 DVSWYLNGRTVQSDDLHKMIVSEKG-LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQL 154
+V W LNG + +D H+ +S KG H+L+ + ++ +DAG + + + + + + +L
Sbjct: 2587 EVEWSLNGMPLYNDSFHE--ISHKGRRHTLVLKSIQRADAG----IVRASSLKVSTSARL 2640
Query: 155 DVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISL 214
+V K +F+ E ++ L+C++S P + W+++ VQ
Sbjct: 2641 EVRVK----PVVFLKALDDLSAEERGTLALQCEVSD-PEAHVVWRKDG--VQLGPSDKYD 2693
Query: 215 YQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
+ G L++ DV+ +DAG YT +E
Sbjct: 2694 FLHTAGTRGLVVHDVSPEDAGLYTCHVGSE 2723
Score = 47.4 bits (111), Expect = 2e-05
Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 11/164 (6%)
Query: 76 SIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVV--RASD 133
++ EG+ R+ V+G P P+ W +G+ V H +V E + + +++ + SD
Sbjct: 248 TVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRH--VVYEDAQENFVLKILFCKQSD 305
Query: 134 AGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPP 193
G Y C A N G+ T++ VL + A F + Q +V E +S C++ P
Sbjct: 306 RGLYTCTASNLVGQ-TYS---SVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQ-PS 360
Query: 194 PKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
+ W + E + + + + ++ T R L +++V+ D Y
Sbjct: 361 TEAAWFK-EETRLWASAKYGIEEEGTER-RLTVRNVSADDDAVY 402
Score = 46.2 bits (108), Expect = 4e-05
Identities = 44/190 (23%), Positives = 85/190 (44%), Gaps = 15/190 (7%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F + +++ +EG + ++S P V W G +Q++ + + + L+
Sbjct: 3890 PVFREPLQSLQAEEGSTATLQCELSE-PTATVVWSKGGLQLQANGRREPRL-QGCTAELV 3947
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPM-FIYKPQSKKVLEGDSVKL 184
+ ++ D G Y C ++A AT TV AP+ F+ + Q ++V EG + L
Sbjct: 3948 LQDLQREDTGEYTCTCGSQATSATLTV---------TAAPVRFLRELQHQEVDEGGTAHL 3998
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
C++S + W R + F + + QD LL++ V ++DAG YT +
Sbjct: 3999 CCELSR-AGASVEW-RKGSLQLFPCAKYQMVQDGAA-AELLVRGVEQEDAGDYTCDTGHT 4055
Query: 245 AGVTTCNTRL 254
+ + + R+
Sbjct: 4056 QSMASLSVRV 4065
Score = 45.8 bits (107), Expect = 5e-05
Identities = 34/144 (23%), Positives = 55/144 (38%), Gaps = 7/144 (4%)
Query: 18 QDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYPPRFIQVPENMSI 77
++DSG + N+ A ++++ R + + E+ PPR ++ +
Sbjct: 5325 REDSGQYAAYISNAMGAAYS--SARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKV 5382
Query: 78 DEGRFCRMDFKVSGLPAPDVSWYLNGRT-----VQSDDLHKMIVSEKGLHSLIFEVVRAS 132
+G KV G P P V W + D + S HSL+ V
Sbjct: 5383 KKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQ 5442
Query: 133 DAGAYACVAKNRAGEATFTVQLDV 156
G Y C+A N AG+A + L V
Sbjct: 5443 HQGTYTCIASNAAGQALCSASLHV 5466
Score = 45.1 bits (105), Expect = 8e-05
Identities = 44/200 (22%), Positives = 84/200 (42%), Gaps = 15/200 (7%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 132
E++ + EG ++S V W+L+ + +++L+++ G H L +
Sbjct: 3012 EDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALK 3071
Query: 133 DAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIP 192
D+G A ++ A V ++ +F + + EG+ + L C+ S
Sbjct: 3072 DSGTIYFEAGDQRASAALRVT--------EKPSVFSRELTDATITEGEDLTLVCETSTCD 3123
Query: 193 PPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
P + W ++ + ++ + R L + R LLI +D+G Y EAG ++
Sbjct: 3124 IP-VCWTKDGKTLR-GSARCQLSHEG-HRAQLLITGATLQDSGRYKC----EAGGACSSS 3176
Query: 253 RLDVTARPNQTLPAPKQLRV 272
+ V ARP + A K L V
Sbjct: 3177 IVRVHARPVRFQEALKDLEV 3196
Score = 45.1 bits (105), Expect = 8e-05
Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 23/200 (11%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLH-S 123
P RFI+ +N EG + +++ A V W T++ D + + + G
Sbjct: 3537 PARFIEDVKNQEAREGATAVLQCELNS--AAPVEWRKGSETLRDGDRYSL--RQDGTKCE 3592
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQ-LDVLAKEHKRAPMFIYKPQSKKVLEGDSV 182
L + +D G Y+CV A TV+ L + E R +++ EG +
Sbjct: 3593 LQIRGLAMADTGEYSCVCGQERTSAMLTVRALPIKFTEGLR---------NEEATEGATA 3643
Query: 183 KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAV 242
L C++S + P + W + +E ++ + DR SL QD R L I+ + +DAG Y
Sbjct: 3644 VLRCELSKMAPVE--WWKGHETLR-DGDRHSLRQDG-ARCELQIRGLVAEDAGEYLCM-- 3697
Query: 243 NEAGVTTCNTRLDVTARPNQ 262
G + L V A P++
Sbjct: 3698 --CGKERTSAMLTVRAMPSK 3715
Score = 44.7 bits (104), Expect = 1e-04
Identities = 37/113 (32%), Positives = 53/113 (46%), Gaps = 5/113 (4%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQD-NTGRV 222
AP F+ +P++ V G L CQI P P++ W+++ + V R L QD + R+
Sbjct: 9 APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGA-RFRLAQDGDLYRL 67
Query: 223 TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPT 275
T+L D+ D+G Y A N G L V A AP L +RPT
Sbjct: 68 TIL--DLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFL-LRPT 117
Score = 40.8 bits (94), Expect = 0.002
Identities = 48/190 (25%), Positives = 78/190 (41%), Gaps = 17/190 (8%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P FI + EG + ++S A V W +++ D H + + + L
Sbjct: 3361 PAHFIGRLRHQESIEGATATLRCELS--KAAPVEWRKGRESLRDGDRHSLR-QDGAVCEL 3417
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAP-MFIYKPQSKKVLEGDSVK 183
+ +DAG Y+CV AT TV K P F ++++ +EG +
Sbjct: 3418 QICGLAVADAGEYSCVCGEERTSATLTV---------KALPAKFTEGLRNEEAVEGATAM 3468
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
L C++S + P + W++ E ++ + DR L Q+ T R L I + DAG Y
Sbjct: 3469 LWCELSKVAPVE--WRKGPENLR-DGDRYILRQEGT-RCELQICGLAMADAGEYLCVCGQ 3524
Query: 244 EAGVTTCNTR 253
E T R
Sbjct: 3525 ERTSATLTIR 3534
Score = 39.7 bits (91), Expect = 0.004
Identities = 44/157 (28%), Positives = 63/157 (40%), Gaps = 27/157 (17%)
Query: 122 HSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKV-LEGD 180
++LI+ V A DAG VA+N A V K P+ + +P K+ +E
Sbjct: 2255 YTLIYRRVLAEDAGEIQFVAENAESRAQLRV---------KELPVTLVRPLRDKIAMEKH 2305
Query: 181 SVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVS 240
LECQ+S ++K + E+ + L D R L+I DV+ +D YT
Sbjct: 2306 RGVLECQVSRASAQVRWFKGSQELQP--GPKYELVSDGLYR-KLIISDVHAEDEDTYTCD 2362
Query: 241 A----------VNEAGVTTCNTRLDVTARPNQTLPAP 267
A V E +T DVT PAP
Sbjct: 2363 AGDVKTSAQFFVEEQSITIVRGLQDVTVME----PAP 2395
Score = 38.9 bits (89), Expect = 0.006
Identities = 43/172 (25%), Positives = 74/172 (43%), Gaps = 27/172 (15%)
Query: 93 PAPDVSWYLNGRTVQSDDLHKMIVSEKGL-HSLIFEVVRASDAGAYACVAKNRAGEATFT 151
P +V+WY +G+ + S +M V KG L+ + V +DAG Y+C AG +
Sbjct: 1193 PQTEVTWYKDGKKLSSSSKVRMEV--KGCTRRLVVQQVGKADAGEYSC----EAGGQRVS 1246
Query: 152 VQLDVLAKEHKRAPMFIYKPQ-----SKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQ 206
QL H P ++ + + G S L C+++ ++K ++
Sbjct: 1247 FQL------HITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQTEVTWYKDGKKLSS 1300
Query: 207 FNTDRISLYQDNTGRV-TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVT 257
+ RI + G + L+++ + DAG YT EAG + LDV+
Sbjct: 1301 SSKVRI----EAAGCMRQLVVQQAGQADAGEYTC----EAGGQRLSFHLDVS 1344
Score = 38.5 bits (88), Expect = 0.008
Identities = 17/61 (27%), Positives = 28/61 (45%)
Query: 92 LPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFT 151
+P + SWY+NG VQ DD + ++ H+L+ + AG ++ A T
Sbjct: 4459 VPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACRDAVASARLT 4518
Query: 152 V 152
V
Sbjct: 4519 V 4519
Score = 38.1 bits (87), Expect = 0.010
Identities = 36/148 (24%), Positives = 66/148 (44%), Gaps = 15/148 (10%)
Query: 94 APDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQ 153
A V+W +GRT+ +++ S G L+ V DAG Y CV +R G + +
Sbjct: 734 AAAVTWLKDGRTLSPGPKYEVQASA-GRRVLLVRDVARDDAGLYECV--SRGGRIAYQLS 790
Query: 154 LDVLAKEHKRAPMFIYKPQSKKVLE---GDSVKLECQISAIPPPKLFWKRNNEMVQFNTD 210
+ LA+ F++K + ++ G + EC+ S + W ++ + + +
Sbjct: 791 VQGLAR-------FLHKDMAGSCVDAVAGGPAQFECETSE-AHVHVHWYKDGMELGHSGE 842
Query: 211 RISLYQDNTGRVTLLIKDVNKKDAGWYT 238
R L +D R L+ V ++D G Y+
Sbjct: 843 RF-LQEDVGTRHRLVAATVTRQDEGTYS 869
Score = 37.7 bits (86), Expect = 0.013
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 10/127 (7%)
Query: 115 IVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK 174
+V+E + SL +RA DAG Y C +++ A TV + + K F+ +
Sbjct: 1856 MVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVK-------FMSGLSTV 1908
Query: 175 KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDA 234
EG +C +S + W R+ ++Q +++ ++ Q +L I D+ +DA
Sbjct: 1909 VAEEGGEATFQCVVSP-SDVAVVWFRDGALLQ-PSEKFAISQSGASH-SLTISDLVLEDA 1965
Query: 235 GWYTVSA 241
G TV A
Sbjct: 1966 GQITVEA 1972
Score = 37.4 bits (85), Expect = 0.017
Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Query: 160 EHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNN-EMVQFNTDRISLYQDN 218
+ + PMF + + GD+++LEC +++ + W ++ E+ I D
Sbjct: 4893 KQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDG 4952
Query: 219 TGRVTLLIKDVNKKDAGWYTVSAVNEAGVTT 249
T +LLI +++ DAG YT N+ G T
Sbjct: 4953 T--CSLLITGLDRADAGCYTCQVSNKFGQVT 4981
Score = 34.7 bits (78), Expect = 0.11
Identities = 33/137 (24%), Positives = 58/137 (42%), Gaps = 10/137 (7%)
Query: 53 VNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLH 112
V+ ++ + P F++ +++S +E + +VS P V W +G + D +
Sbjct: 2634 VSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVSD-PEAHVVWRKDGVQLGPSDKY 2692
Query: 113 KMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQ 172
+ + G L+ V DAG Y C + A V D+ KR +
Sbjct: 2693 DFLHTA-GTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVH-DLHVGITKRL-------K 2743
Query: 173 SKKVLEGDSVKLECQIS 189
+ +VLEG+S EC +S
Sbjct: 2744 TMEVLEGESCSFECVLS 2760
Score = 33.5 bits (75), Expect = 0.25
Identities = 45/206 (21%), Positives = 81/206 (39%), Gaps = 18/206 (8%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDV-SWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P+F +++ + G R+ ++S + V W G + + ++M S+ L
Sbjct: 4068 PKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMR-SQGATREL 4126
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
+ + A D G YACV + A+ V + + +V + V+
Sbjct: 4127 LIHQLEAKDTGEYACVTGGQKTAASLRVT--------EPEVTIVRGLVDAEVTADEDVEF 4178
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV-TLLIKDVNKKDAGWYTVSAVN 243
C++S + W +Q N ++ GR+ TL +K V +DAG + N
Sbjct: 4179 SCEVSRAGATGVQWCLQGLPLQSN--EVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGN 4236
Query: 244 EAGVTTCNTRLDVTARPNQTLPAPKQ 269
A + +L V A P T+ P Q
Sbjct: 4237 HAS----SAQLTVRA-PEVTILEPLQ 4257
Score = 31.6 bits (70), Expect = 0.96
Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 3/100 (3%)
Query: 138 ACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLF 197
A V AGE Q LA+ K P P+S++V G+ V LE ++ A ++
Sbjct: 4597 AAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQVAAGEDVSLELEVVA-EAGEVI 4655
Query: 198 WKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
W + E +Q R + ++ L+IK +D G Y
Sbjct: 4656 WHKGMERIQ-PGGRFEVVSQGRQQM-LVIKGFTAEDQGEY 4693
Score = 30.4 bits (67), Expect = 2.1
Identities = 35/163 (21%), Positives = 67/163 (41%), Gaps = 18/163 (11%)
Query: 97 VSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDV 156
V WY +G + + H L+ V D G Y+C R GE + +L V
Sbjct: 828 VHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSC----RVGEDSVDFRLRV 883
Query: 157 LAKEHKRAPMFIYKPQSKKVLE---GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRIS 213
+ +F + +++ L+ G S L C+++ ++K ++ ++ ++
Sbjct: 884 ----SEPKVVFAKEQLARRKLQAEAGASATLSCEVAQAQTEVTWYKDGKKL--SSSSKVC 937
Query: 214 LYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
+ R L+++ + DAG Y+ EAG + LDV
Sbjct: 938 MEATGCTR-RLVVQQAGQADAGEYSC----EAGGQRLSFHLDV 975
Score = 28.9 bits (63), Expect = 6.2
Identities = 21/95 (22%), Positives = 35/95 (36%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F + G R++ V+ W +G + H + G SL+
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLL 4957
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE 160
+ +DAG Y C N+ G+ T + + V E
Sbjct: 4958 ITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSE 4992
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 91.3 bits (225), Expect = 1e-18
Identities = 60/244 (24%), Positives = 110/244 (45%), Gaps = 8/244 (3%)
Query: 16 QAQDDSGAQDSQQHNSEHAR---LQVPTSQVRSRSTSRGDVNDQDAIQEKFYPPRFIQVP 72
Q + D A + Q + R LQ T+ ++S Q + PP F +
Sbjct: 5961 QVEGDDRAFEVWQEREDSVRKYLLQARTAIIKSSWVKEICGIQQRLALPVWRPPDFEEEL 6020
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 132
+ + + G ++ +V+G P P +SWY +G+ VQ D H +I G +LI + +
Sbjct: 6021 ADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGV 6080
Query: 133 DAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIP 192
D+G Y C A + AG + ++ V + P F+ K ++ +EG+ + C I P
Sbjct: 6081 DSGQYMCFAASAAGNCSTLGKILV-----QVPPRFVNKVRASPFVEGEDAQFTCTIEGAP 6135
Query: 193 PPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
P++ W ++ ++ +L + +G + L+I+ +K+D G Y VN G +
Sbjct: 6136 YPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASA 6195
Query: 253 RLDV 256
L +
Sbjct: 6196 ELRI 6199
Score = 78.2 bits (191), Expect = 9e-15
Identities = 54/205 (26%), Positives = 90/205 (43%), Gaps = 5/205 (2%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
PRF+ P+ + G+ + ++ G P P VSW + + V + ++ + L+ L
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRL-AQDGDLYRLT 68
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTV--QLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
+ D+G Y C A+N GEA V Q+D A ++AP F+ +P S +V EG
Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEAT 128
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLL-IKDVNKKDAGWYTVSAV 242
C++ P P + W ++ + D + + G + L I+ +D G Y V A
Sbjct: 129 FRCRVGGSPRPAVSWSKDGRRLG-EPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAE 187
Query: 243 NEAGVTTCNTRLDVTARPNQTLPAP 267
N G + L V + T P
Sbjct: 188 NPLGAASAAAALVVDSDAADTASRP 212
Score = 67.0 bits (162), Expect = 2e-11
Identities = 54/212 (25%), Positives = 91/212 (42%), Gaps = 18/212 (8%)
Query: 66 PRFIQVPENMSIDEG-RFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P+ ++ ++ + G R + KV G PAP + W+ +G+ + + H + +K LH+L
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTA-SAHIRMTDKKILHTL 5318
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLA---KEHKRA---------PMFIYKPQ 172
V D+G YA N G A + +L V E K A P + +
Sbjct: 5319 EIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFT 5378
Query: 173 SKKVLEGDSVKLECQISAIPPPKLFWKRNNE---MVQFNTDRIS-LYQDNTGRVTLLIKD 228
KKV +G S+ ++ P P + W R ++ D + + +L++ D
Sbjct: 5379 PKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLD 5438
Query: 229 VNKKDAGWYTVSAVNEAGVTTCNTRLDVTARP 260
V ++ G YT A N AG C+ L V+ P
Sbjct: 5439 VGRQHQGTYTCIASNAAGQALCSASLHVSGLP 5470
Score = 65.9 bits (159), Expect = 5e-11
Identities = 51/230 (22%), Positives = 96/230 (41%), Gaps = 48/230 (20%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F+ +N + +G D V+G P P V W+ +G+ ++ DD + + ++G H LI
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQL--DVLAKEHKRA------------------- 164
V +D G Y C+A+N G ++ +L D+ + ++ A
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSSR 5245
Query: 165 --------------PMFIYKPQSKKVLEGDSV-KLECQISAIPPPKLFWKRNNEMVQFN- 208
P + + + +V G + K + ++ P P+L+W ++ + + +
Sbjct: 5246 EQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASA 5305
Query: 209 ----TDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRL 254
TD+ L+ TL I V ++D+G Y N G + RL
Sbjct: 5306 HIRMTDKKILH-------TLEIISVTREDSGQYAAYISNAMGAAYSSARL 5348
Score = 64.7 bits (156), Expect = 1e-10
Identities = 56/212 (26%), Positives = 83/212 (39%), Gaps = 30/212 (14%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F+ P ++ + EG +V G P P VSW +GR + D ++ V E G S +
Sbjct: 110 PHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASAL 169
Query: 126 -FEVVRASDAGAYACVAKNRAGEATFTVQLDVLA-----------------------KEH 161
R D G Y A+N G A+ L V + +E
Sbjct: 170 RIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREA 229
Query: 162 KRAPMFIYKPQSK-----KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQ 216
RA P S V EG +L C ++ P P+ WK++ ++V + +Y+
Sbjct: 230 MRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHV-VYE 288
Query: 217 DNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVT 248
D L I + D G YT +A N G T
Sbjct: 289 DAQENFVLKILFCKQSDRGLYTCTASNLVGQT 320
Score = 53.5 bits (127), Expect = 2e-07
Identities = 55/204 (26%), Positives = 85/204 (41%), Gaps = 17/204 (8%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P +FI+ N EG + ++S A V W T++ D H + + L
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCELS--KAAPVEWRKGHETLRDGDRHSLR-QDGSRCEL 3769
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
+ DAG Y+CV AT TV+ FI ++++ EG + L
Sbjct: 3770 QIRGLAVVDAGEYSCVCGQERTSATLTVR--------ALPARFIEDVKNQEAREGATAVL 3821
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
+C++S P + W++ +E ++ DR SL QD T R L I ++ D G Y+ E
Sbjct: 3822 QCELSKAAPVE--WRKGSETLR-GGDRYSLRQDGT-RCELQIHGLSVADTGEYSCVCGQE 3877
Query: 245 AGVTTCNTRL--DVTARPNQTLPA 266
T R V P Q+L A
Sbjct: 3878 RTSATLTVRAPQPVFREPLQSLQA 3901
Score = 52.4 bits (124), Expect = 5e-07
Identities = 44/187 (23%), Positives = 82/187 (43%), Gaps = 12/187 (6%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 132
+++ + EG+ ++S + W L G +Q+++++ + V + LH L V
Sbjct: 4257 QDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLE 4316
Query: 133 DAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIP 192
DAG + G + QL V AK + ++ + LEG ECQ+S
Sbjct: 4317 DAGTVSF----HVGTCSSEAQLKVTAKN-----TVVRGLENVEALEGGEALFECQLSQPE 4367
Query: 193 PPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSA---VNEAGVTT 249
W ++E V + + ++ +N R LL+K++ +D+ T A V A +T
Sbjct: 4368 VAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRVTFLAGDMVTSAFLTV 4427
Query: 250 CNTRLDV 256
RL++
Sbjct: 4428 RGWRLEI 4434
Score = 50.1 bits (118), Expect = 3e-06
Identities = 53/189 (28%), Positives = 85/189 (44%), Gaps = 15/189 (7%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P +F + N EG + ++S + AP V W+ T++ D H +
Sbjct: 3625 PIKFTEGLRNEEATEGATAVLRCELSKM-AP-VEWWKGHETLRDGDRHSLRQDGARCELQ 3682
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
I +V A DAG Y C+ G+ + L V A K FI ++++ EGD+ L
Sbjct: 3683 IRGLV-AEDAGEYLCM----CGKERTSAMLTVRAMPSK----FIEGLRNEEATEGDTATL 3733
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
C++S P + W++ +E ++ + DR SL QD + R L I+ + DAG Y+ E
Sbjct: 3734 WCELSKAAPVE--WRKGHETLR-DGDRHSLRQDGS-RCELQIRGLAVVDAGEYSCVCGQE 3789
Query: 245 AGVTTCNTR 253
T R
Sbjct: 3790 RTSATLTVR 3798
Score = 48.1 bits (113), Expect = 1e-05
Identities = 53/213 (24%), Positives = 92/213 (43%), Gaps = 19/213 (8%)
Query: 51 GDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD 110
GD A++ P F + + +I EG + + S P V W +G+T++
Sbjct: 3081 GDQRASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSA 3139
Query: 111 LHKMIVSEKGLHS-LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIY 169
+ +S +G + L+ D+G Y C A + + + H R F
Sbjct: 3140 --RCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSS--------IVRVHARPVRFQE 3189
Query: 170 KPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDV 229
+ +VLEG + L C +S++ P + NN V D+ SL Q+ + L+++++
Sbjct: 3190 ALKDLEVLEGGAATLRCVLSSVAAPVKWCYGNN--VLRPGDKYSLRQEG-AMLELVVRNL 3246
Query: 230 NKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQ 262
+D+G Y+ S G T + L VTA P Q
Sbjct: 3247 RPQDSGRYSCS----FGDQTTSATLTVTALPAQ 3275
Score = 48.1 bits (113), Expect = 1e-05
Identities = 49/174 (28%), Positives = 76/174 (43%), Gaps = 17/174 (9%)
Query: 88 KVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGE 147
+VS A V W L G +QS+++ ++ V + +H+L + V DAG + N A
Sbjct: 4181 EVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASS 4240
Query: 148 ATFTVQLDVLAKEHKRAP-MFIYKP-QSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMV 205
A TV RAP + I +P Q ++ EG +C++S + W +
Sbjct: 4241 AQLTV----------RAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPL 4290
Query: 206 QFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 259
Q N + T + L K V +DAG TVS G + +L VTA+
Sbjct: 4291 QANEMNDITVEQGTLHLLTLHK-VTLEDAG--TVSF--HVGTCSSEAQLKVTAK 4339
Score = 48.1 bits (113), Expect = 1e-05
Identities = 29/102 (28%), Positives = 52/102 (50%), Gaps = 3/102 (2%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT 223
AP+F+ + Q+++V +G V +C ++ P P + W ++ ++++ D + +D G
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLE-EDDHYMINEDQQGGHQ 5183
Query: 224 LLIKDVNKKDAGWYTVSAVNEAGV--TTCNTRLDVTARPNQT 263
L+I V D G Y A N GV T R+D+T+ T
Sbjct: 5184 LIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDT 5225
Score = 48.1 bits (113), Expect = 1e-05
Identities = 28/99 (28%), Positives = 50/99 (50%), Gaps = 3/99 (3%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGL-HS 123
PP E++ G + + + G P P V+WY + +VQ D ++ ++G +S
Sbjct: 6356 PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKD--SVQLVDSTRLSQQQEGTTYS 6413
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHK 162
L+ V + DAG Y C+A+N G+ +L VL +++
Sbjct: 6414 LVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNE 6452
Score = 47.8 bits (112), Expect = 1e-05
Identities = 37/150 (24%), Positives = 73/150 (48%), Gaps = 14/150 (9%)
Query: 96 DVSWYLNGRTVQSDDLHKMIVSEKG-LHSLIFEVVRASDAGAYACVAKNRAGEATFTVQL 154
+V W LNG + +D H+ +S KG H+L+ + ++ +DAG + + + + + + +L
Sbjct: 2587 EVEWSLNGMPLYNDSFHE--ISHKGRRHTLVLKSIQRADAG----IVRASSLKVSTSARL 2640
Query: 155 DVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISL 214
+V K +F+ E ++ L+C++S P + W+++ VQ
Sbjct: 2641 EVRVK----PVVFLKALDDLSAEERGTLALQCEVSD-PEAHVVWRKDG--VQLGPSDKYD 2693
Query: 215 YQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
+ G L++ DV+ +DAG YT +E
Sbjct: 2694 FLHTAGTRGLVVHDVSPEDAGLYTCHVGSE 2723
Score = 47.8 bits (112), Expect = 1e-05
Identities = 35/110 (31%), Positives = 53/110 (48%), Gaps = 4/110 (3%)
Query: 159 KEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTD-RISLYQD 217
K RAP F+ + + V+ G SV L CQ+SA P + W ++ ++ ++ IS
Sbjct: 7457 KSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLK 7516
Query: 218 NTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAP 267
N +T+L+ V +D G YT S N G T L RP+ + P P
Sbjct: 7517 NFQLLTILV--VVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSS-PCP 7563
Score = 47.4 bits (111), Expect = 2e-05
Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 11/164 (6%)
Query: 76 SIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVV--RASD 133
++ EG+ R+ V+G P P+ W +G+ V H +V E + + +++ + SD
Sbjct: 248 TVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRH--VVYEDAQENFVLKILFCKQSD 305
Query: 134 AGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPP 193
G Y C A N G+ T++ VL + A F + Q +V E +S C++ P
Sbjct: 306 RGLYTCTASNLVGQ-TYS---SVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQ-PS 360
Query: 194 PKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
+ W + E + + + + ++ T R L +++V+ D Y
Sbjct: 361 TEAAWFK-EETRLWASAKYGIEEEGTER-RLTVRNVSADDDAVY 402
Score = 46.2 bits (108), Expect = 4e-05
Identities = 44/190 (23%), Positives = 85/190 (44%), Gaps = 15/190 (7%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F + +++ +EG + ++S P V W G +Q++ + + + L+
Sbjct: 3890 PVFREPLQSLQAEEGSTATLQCELSE-PTATVVWSKGGLQLQANGRREPRL-QGCTAELV 3947
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPM-FIYKPQSKKVLEGDSVKL 184
+ ++ D G Y C ++A AT TV AP+ F+ + Q ++V EG + L
Sbjct: 3948 LQDLQREDTGEYTCTCGSQATSATLTV---------TAAPVRFLRELQHQEVDEGGTAHL 3998
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
C++S + W R + F + + QD LL++ V ++DAG YT +
Sbjct: 3999 CCELSR-AGASVEW-RKGSLQLFPCAKYQMVQDGAA-AELLVRGVEQEDAGDYTCDTGHT 4055
Query: 245 AGVTTCNTRL 254
+ + + R+
Sbjct: 4056 QSMASLSVRV 4065
Score = 45.8 bits (107), Expect = 5e-05
Identities = 34/144 (23%), Positives = 55/144 (38%), Gaps = 7/144 (4%)
Query: 18 QDDSGAQDSQQHNSEHARLQVPTSQVRSRSTSRGDVNDQDAIQEKFYPPRFIQVPENMSI 77
++DSG + N+ A ++++ R + + E+ PPR ++ +
Sbjct: 5325 REDSGQYAAYISNAMGAAYS--SARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKV 5382
Query: 78 DEGRFCRMDFKVSGLPAPDVSWYLNGRT-----VQSDDLHKMIVSEKGLHSLIFEVVRAS 132
+G KV G P P V W + D + S HSL+ V
Sbjct: 5383 KKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQ 5442
Query: 133 DAGAYACVAKNRAGEATFTVQLDV 156
G Y C+A N AG+A + L V
Sbjct: 5443 HQGTYTCIASNAAGQALCSASLHV 5466
Score = 45.1 bits (105), Expect = 8e-05
Identities = 44/200 (22%), Positives = 84/200 (42%), Gaps = 15/200 (7%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS 132
E++ + EG ++S V W+L+ + +++L+++ G H L +
Sbjct: 3012 EDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALK 3071
Query: 133 DAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIP 192
D+G A ++ A V ++ +F + + EG+ + L C+ S
Sbjct: 3072 DSGTIYFEAGDQRASAALRVT--------EKPSVFSRELTDATITEGEDLTLVCETSTCD 3123
Query: 193 PPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 252
P + W ++ + ++ + R L + R LLI +D+G Y EAG ++
Sbjct: 3124 IP-VCWTKDGKTLR-GSARCQLSHEG-HRAQLLITGATLQDSGRYKC----EAGGACSSS 3176
Query: 253 RLDVTARPNQTLPAPKQLRV 272
+ V ARP + A K L V
Sbjct: 3177 IVRVHARPVRFQEALKDLEV 3196
Score = 45.1 bits (105), Expect = 8e-05
Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 23/200 (11%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLH-S 123
P RFI+ +N EG + +++ A V W T++ D + + + G
Sbjct: 3537 PARFIEDVKNQEAREGATAVLQCELNS--AAPVEWRKGSETLRDGDRYSL--RQDGTKCE 3592
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQ-LDVLAKEHKRAPMFIYKPQSKKVLEGDSV 182
L + +D G Y+CV A TV+ L + E R +++ EG +
Sbjct: 3593 LQIRGLAMADTGEYSCVCGQERTSAMLTVRALPIKFTEGLR---------NEEATEGATA 3643
Query: 183 KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAV 242
L C++S + P + W + +E ++ + DR SL QD R L I+ + +DAG Y
Sbjct: 3644 VLRCELSKMAPVE--WWKGHETLR-DGDRHSLRQDG-ARCELQIRGLVAEDAGEYLCM-- 3697
Query: 243 NEAGVTTCNTRLDVTARPNQ 262
G + L V A P++
Sbjct: 3698 --CGKERTSAMLTVRAMPSK 3715
Score = 44.7 bits (104), Expect = 1e-04
Identities = 37/113 (32%), Positives = 53/113 (46%), Gaps = 5/113 (4%)
Query: 164 APMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQD-NTGRV 222
AP F+ +P++ V G L CQI P P++ W+++ + V R L QD + R+
Sbjct: 9 APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGA-RFRLAQDGDLYRL 67
Query: 223 TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPT 275
T+L D+ D+G Y A N G L V A AP L +RPT
Sbjct: 68 TIL--DLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFL-LRPT 117
Score = 41.6 bits (96), Expect = 0.001
Identities = 36/133 (27%), Positives = 57/133 (42%), Gaps = 5/133 (3%)
Query: 147 EATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQ 206
+ T+T Q + R P + + G + + E I P P + W +++ +
Sbjct: 6341 QRTYTYQ--AIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLV 6398
Query: 207 FNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPA 266
+T R+S Q+ T +L+++ V KDAG YT A N G C L V N+ +
Sbjct: 6399 DST-RLSQQQEGT-TYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEP-DS 6455
Query: 267 PKQLRVRPTFSKY 279
KQ R S Y
Sbjct: 6456 EKQSHRRKLHSFY 6468
Score = 40.8 bits (94), Expect = 0.002
Identities = 48/190 (25%), Positives = 78/190 (41%), Gaps = 17/190 (8%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P FI + EG + ++S A V W +++ D H + + + L
Sbjct: 3361 PAHFIGRLRHQESIEGATATLRCELS--KAAPVEWRKGRESLRDGDRHSLR-QDGAVCEL 3417
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAP-MFIYKPQSKKVLEGDSVK 183
+ +DAG Y+CV AT TV K P F ++++ +EG +
Sbjct: 3418 QICGLAVADAGEYSCVCGEERTSATLTV---------KALPAKFTEGLRNEEAVEGATAM 3468
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
L C++S + P + W++ E ++ + DR L Q+ T R L I + DAG Y
Sbjct: 3469 LWCELSKVAPVE--WRKGPENLR-DGDRYILRQEGT-RCELQICGLAMADAGEYLCVCGQ 3524
Query: 244 EAGVTTCNTR 253
E T R
Sbjct: 3525 ERTSATLTIR 3534
Score = 39.7 bits (91), Expect = 0.004
Identities = 44/157 (28%), Positives = 63/157 (40%), Gaps = 27/157 (17%)
Query: 122 HSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKV-LEGD 180
++LI+ V A DAG VA+N A V K P+ + +P K+ +E
Sbjct: 2255 YTLIYRRVLAEDAGEIQFVAENAESRAQLRV---------KELPVTLVRPLRDKIAMEKH 2305
Query: 181 SVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVS 240
LECQ+S ++K + E+ + L D R L+I DV+ +D YT
Sbjct: 2306 RGVLECQVSRASAQVRWFKGSQELQP--GPKYELVSDGLYR-KLIISDVHAEDEDTYTCD 2362
Query: 241 A----------VNEAGVTTCNTRLDVTARPNQTLPAP 267
A V E +T DVT PAP
Sbjct: 2363 AGDVKTSAQFFVEEQSITIVRGLQDVTVME----PAP 2395
Score = 38.9 bits (89), Expect = 0.006
Identities = 43/172 (25%), Positives = 74/172 (43%), Gaps = 27/172 (15%)
Query: 93 PAPDVSWYLNGRTVQSDDLHKMIVSEKGL-HSLIFEVVRASDAGAYACVAKNRAGEATFT 151
P +V+WY +G+ + S +M V KG L+ + V +DAG Y+C AG +
Sbjct: 1193 PQTEVTWYKDGKKLSSSSKVRMEV--KGCTRRLVVQQVGKADAGEYSC----EAGGQRVS 1246
Query: 152 VQLDVLAKEHKRAPMFIYKPQ-----SKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQ 206
QL H P ++ + + G S L C+++ ++K ++
Sbjct: 1247 FQL------HITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQTEVTWYKDGKKLSS 1300
Query: 207 FNTDRISLYQDNTGRV-TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVT 257
+ RI + G + L+++ + DAG YT EAG + LDV+
Sbjct: 1301 SSKVRI----EAAGCMRQLVVQQAGQADAGEYTC----EAGGQRLSFHLDVS 1344
Score = 38.9 bits (89), Expect = 0.006
Identities = 23/86 (26%), Positives = 37/86 (43%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F++ + ++ G+ + +VS PA +W +G ++S + + K L
Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522
Query: 126 FEVVRASDAGAYACVAKNRAGEATFT 151
VV A D G Y C N G T T
Sbjct: 7523 ILVVVAEDLGVYTCSVSNALGTVTTT 7548
Score = 38.5 bits (88), Expect = 0.008
Identities = 17/61 (27%), Positives = 28/61 (45%)
Query: 92 LPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFT 151
+P + SWY+NG VQ DD + ++ H+L+ + AG ++ A T
Sbjct: 4459 VPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACRDAVASARLT 4518
Query: 152 V 152
V
Sbjct: 4519 V 4519
Score = 38.1 bits (87), Expect = 0.010
Identities = 36/148 (24%), Positives = 66/148 (44%), Gaps = 15/148 (10%)
Query: 94 APDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQ 153
A V+W +GRT+ +++ S G L+ V DAG Y CV +R G + +
Sbjct: 734 AAAVTWLKDGRTLSPGPKYEVQASA-GRRVLLVRDVARDDAGLYECV--SRGGRIAYQLS 790
Query: 154 LDVLAKEHKRAPMFIYKPQSKKVLE---GDSVKLECQISAIPPPKLFWKRNNEMVQFNTD 210
+ LA+ F++K + ++ G + EC+ S + W ++ + + +
Sbjct: 791 VQGLAR-------FLHKDMAGSCVDAVAGGPAQFECETSE-AHVHVHWYKDGMELGHSGE 842
Query: 211 RISLYQDNTGRVTLLIKDVNKKDAGWYT 238
R L +D R L+ V ++D G Y+
Sbjct: 843 RF-LQEDVGTRHRLVAATVTRQDEGTYS 869
Score = 37.7 bits (86), Expect = 0.013
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 10/127 (7%)
Query: 115 IVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSK 174
+V+E + SL +RA DAG Y C +++ A TV + + K F+ +
Sbjct: 1856 MVAEGPVRSLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVK-------FMSGLSTV 1908
Query: 175 KVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDA 234
EG +C +S + W R+ ++Q +++ ++ Q +L I D+ +DA
Sbjct: 1909 VAEEGGEATFQCVVSP-SDVAVVWFRDGALLQ-PSEKFAISQSGASH-SLTISDLVLEDA 1965
Query: 235 GWYTVSA 241
G TV A
Sbjct: 1966 GQITVEA 1972
Score = 37.4 bits (85), Expect = 0.017
Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Query: 160 EHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNN-EMVQFNTDRISLYQDN 218
+ + PMF + + GD+++LEC +++ + W ++ E+ I D
Sbjct: 4893 KQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDG 4952
Query: 219 TGRVTLLIKDVNKKDAGWYTVSAVNEAGVTT 249
T +LLI +++ DAG YT N+ G T
Sbjct: 4953 T--CSLLITGLDRADAGCYTCQVSNKFGQVT 4981
Score = 34.7 bits (78), Expect = 0.11
Identities = 33/137 (24%), Positives = 58/137 (42%), Gaps = 10/137 (7%)
Query: 53 VNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLH 112
V+ ++ + P F++ +++S +E + +VS P V W +G + D +
Sbjct: 2634 VSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVSD-PEAHVVWRKDGVQLGPSDKY 2692
Query: 113 KMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQ 172
+ + G L+ V DAG Y C + A V D+ KR +
Sbjct: 2693 DFLHTA-GTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVH-DLHVGITKRL-------K 2743
Query: 173 SKKVLEGDSVKLECQIS 189
+ +VLEG+S EC +S
Sbjct: 2744 TMEVLEGESCSFECVLS 2760
Score = 33.5 bits (75), Expect = 0.25
Identities = 45/206 (21%), Positives = 81/206 (39%), Gaps = 18/206 (8%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDV-SWYLNGRTVQSDDLHKMIVSEKGLHSL 124
P+F +++ + G R+ ++S + V W G + + ++M S+ L
Sbjct: 4068 PKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMR-SQGATREL 4126
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
+ + A D G YACV + A+ V + + +V + V+
Sbjct: 4127 LIHQLEAKDTGEYACVTGGQKTAASLRVT--------EPEVTIVRGLVDAEVTADEDVEF 4178
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV-TLLIKDVNKKDAGWYTVSAVN 243
C++S + W +Q N ++ GR+ TL +K V +DAG + N
Sbjct: 4179 SCEVSRAGATGVQWCLQGLPLQSN--EVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGN 4236
Query: 244 EAGVTTCNTRLDVTARPNQTLPAPKQ 269
A + +L V A P T+ P Q
Sbjct: 4237 HAS----SAQLTVRA-PEVTILEPLQ 4257
Score = 31.6 bits (70), Expect = 0.96
Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 3/100 (3%)
Query: 138 ACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLF 197
A V AGE Q LA+ K P P+S++V G+ V LE ++ A ++
Sbjct: 4597 AAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQVAAGEDVSLELEVVA-EAGEVI 4655
Query: 198 WKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
W + E +Q R + ++ L+IK +D G Y
Sbjct: 4656 WHKGMERIQ-PGGRFEVVSQGRQQM-LVIKGFTAEDQGEY 4693
Score = 30.4 bits (67), Expect = 2.1
Identities = 35/163 (21%), Positives = 67/163 (41%), Gaps = 18/163 (11%)
Query: 97 VSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDV 156
V WY +G + + H L+ V D G Y+C R GE + +L V
Sbjct: 828 VHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSC----RVGEDSVDFRLRV 883
Query: 157 LAKEHKRAPMFIYKPQSKKVLE---GDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRIS 213
+ +F + +++ L+ G S L C+++ ++K ++ ++ ++
Sbjct: 884 ----SEPKVVFAKEQLARRKLQAEAGASATLSCEVAQAQTEVTWYKDGKKL--SSSSKVC 937
Query: 214 LYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDV 256
+ R L+++ + DAG Y+ EAG + LDV
Sbjct: 938 MEATGCTR-RLVVQQAGQADAGEYSC----EAGGQRLSFHLDV 975
Score = 28.9 bits (63), Expect = 6.2
Identities = 21/95 (22%), Positives = 35/95 (36%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F + G R++ V+ W +G + H + G SL+
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLL 4957
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKE 160
+ +DAG Y C N+ G+ T + + V E
Sbjct: 4958 ITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSE 4992
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 90.5 bits (223), Expect = 2e-18
Identities = 64/216 (29%), Positives = 105/216 (48%), Gaps = 22/216 (10%)
Query: 73 ENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRA- 131
EN+++ F + +VSG P PD+SW N + ++ + ++ + L +++RA
Sbjct: 2972 ENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTL-----QIIRAK 3026
Query: 132 -SDAGAYACVAKNRAGEA----TFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLEC 186
SD G Y C+A N+AGE+ + TV + K+H + + V EG SV LEC
Sbjct: 3027 VSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVN-----VREGTSVSLEC 3081
Query: 187 QISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
+ +A+PPP + W +N M+ +T + + D L IK D G Y A+N AG
Sbjct: 3082 ESNAVPPPVITWYKNGRMITEST-HVEILADGQ---MLHIKKAEVSDTGQYVCRAINVAG 3137
Query: 247 VTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLAL 282
N L+V P ++ P++ + T S + L
Sbjct: 3138 RDDKNFHLNVYVPP--SIEGPEREVIVETISNPVTL 3171
Score = 87.8 bits (216), Expect = 1e-17
Identities = 58/193 (30%), Positives = 95/193 (49%), Gaps = 15/193 (7%)
Query: 71 VPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVR 130
+PE +++ + ++ SG PAP SW +G+ + DD HK + + + L L ++
Sbjct: 2878 LPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI-- 2935
Query: 131 ASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKK--VLEGDSVKLECQI 188
+D G Y CVA+N AG A L+V P + P+S+ V+ + + L C++
Sbjct: 2936 -TDIGRYVCVAENTAGSAKKYFNLNV------HVPPSVIGPKSENLTVVVNNFISLTCEV 2988
Query: 189 SAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVT 248
S PPP L W +N + ++ NT+ + + G TL I D G YT A+N+AG +
Sbjct: 2989 SGFPPPDLSWLKNEQPIKLNTNTLIV----PGGRTLQIIRAKVSDGGEYTCIAINQAGES 3044
Query: 249 TCNTRLDVTARPN 261
L V P+
Sbjct: 3045 KKKFSLTVYVPPS 3057
Score = 85.1 bits (209), Expect = 7e-17
Identities = 56/182 (30%), Positives = 87/182 (47%), Gaps = 14/182 (7%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PPR + +++E + G+P P ++W + + ++ L K G L
Sbjct: 4168 PPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDN-VLLANLLGKYTAEPYG--EL 4224
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
I E V D+G Y CVA N AGE T TV L V P F P + +G+ ++L
Sbjct: 4225 ILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHV-----LPTFTELPGDVSLNKGEQLRL 4279
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
C+ + IP PKL W NN ++ + D ++ G L+I+ V+K+D+G Y +A N
Sbjct: 4280 SCKATGIPLPKLTWTFNNNIIPAHFDSVN------GHSELVIERVSKEDSGTYVCTAENS 4333
Query: 245 AG 246
G
Sbjct: 4334 VG 4335
Score = 77.8 bits (190), Expect = 1e-14
Identities = 63/238 (26%), Positives = 108/238 (45%), Gaps = 19/238 (7%)
Query: 34 ARLQVPTSQVRSRSTSRGDVNDQDAIQEKFY------PPRFI--QVPENMSIDEGRFCRM 85
++LQ+ SQ ++ + +K+Y PP ++P ++S+ G +
Sbjct: 3207 SKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVEL 3266
Query: 86 DFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRA 145
+G+P P + W +G+ + S + ++ VS G I+ + SD G Y CVA N A
Sbjct: 3267 VCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGAL-TSDTGKYTCVATNPA 3325
Query: 146 GEATFTVQLDVLAKEHKRAPMFIYKPQSKKV--LEGDSVKLECQISAIPPPKLFWKRNNE 203
GE L+V R K +++K+ L S+ +EC+ + PPP++ W +N
Sbjct: 3326 GEEDRIFNLNVYVTPTIRG----NKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGL 3381
Query: 204 MVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPN 261
+ ++ I L G+V +++ D YT A N AGV + L V A PN
Sbjct: 3382 PLPLSS-HIRLLA--AGQVIRIVR-AQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPN 3435
Score = 77.4 bits (189), Expect = 2e-14
Identities = 57/194 (29%), Positives = 87/194 (44%), Gaps = 12/194 (6%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P+ + V + + G M+ K SG+P P V W+ ++ ++ + L L
Sbjct: 702 PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTF---LIIDPLLGLLK 758
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLE 185
+ + DAG Y CVA N AG AT + LDV + P+FI +P + G +V L
Sbjct: 759 IQETQDLDAGDYTCVAINEAGRATGKITLDVGSP-----PVFIQEPADVSMEIGSNVTLP 813
Query: 186 CQISAIPPPKLFWKRNNEMVQFNT--DRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
C + P P + W+R + M F+ S+ Q TG L I ++ D G Y A N
Sbjct: 814 CYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTG--ALFILNLWASDKGTYICEAEN 871
Query: 244 EAGVTTCNTRLDVT 257
+ G T + VT
Sbjct: 872 QFGKIQSETTVTVT 885
Score = 76.3 bits (186), Expect = 3e-14
Identities = 54/190 (28%), Positives = 87/190 (45%), Gaps = 13/190 (6%)
Query: 75 MSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDA 134
+++ EG + + SG+P P++ W G V +D + ++ + G L + SDA
Sbjct: 2206 LTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGG-RQLQISIAEKSDA 2264
Query: 135 GAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYK---PQSKKVLEGDSVKLECQISAI 191
Y+CVA N AG A L V + P P V G S+ LEC++ I
Sbjct: 2265 ALYSCVASNVAGTAKKEYNLQVYIR-----PTITNSGSHPTEIIVTRGKSISLECEVQGI 2319
Query: 192 PPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCN 251
PPP + W ++ + + + + G + L +K+++ D G Y AVN AG+T
Sbjct: 2320 PPPTVTWMKDGHPL-IKAKGVEILDE--GHI-LQLKNIHVSDTGRYVCVAVNVAGMTDKK 2375
Query: 252 TRLDVTARPN 261
L V A P+
Sbjct: 2376 YDLSVHAPPS 2385
Score = 75.9 bits (185), Expect = 4e-14
Identities = 55/196 (28%), Positives = 85/196 (43%), Gaps = 13/196 (6%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP+ +P+N S G + +G P P ++W +N + H+ ++ G +L
Sbjct: 611 PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGS--HRYRMTSDG--TL 666
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
+ DAG Y C+A N AG L + AP + V GD +
Sbjct: 667 FIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYI-----EAPKLMVVQSELLVALGDITVM 721
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
EC+ S IPPP++ W + + ++ + G L I++ DAG YT A+NE
Sbjct: 722 ECKTSGIPPPQVKWFKGD--LELRPSTFLIIDPLLG--LLKIQETQDLDAGDYTCVAINE 777
Query: 245 AGVTTCNTRLDVTARP 260
AG T LDV + P
Sbjct: 778 AGRATGKITLDVGSPP 793
Score = 74.3 bits (181), Expect = 1e-13
Identities = 57/201 (28%), Positives = 90/201 (44%), Gaps = 18/201 (8%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F ++P ++S+++G R+ K +G+P P ++W N + + S G L+
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAH-----FDSVNGHSELV 4314
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFI--YKPQSKKVLEGDSVK 183
E V D+G Y C A+N G + V K P+F Y + L G+++
Sbjct: 4315 IERVSKEDSGTYVCTAENSVGFVKAIGFVYV-----KEPPVFKGDYPSNWIEPLGGNAI- 4368
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
L C++ P P + W R ++ IS G +L I +DAG YT A N
Sbjct: 4369 LNCEVKGDPTPTIQWNRKGVDIE-----ISHRIRQLGNGSLAIYGTVNEDAGDYTCVATN 4423
Query: 244 EAGVTTCNTRLDVTARPNQTL 264
EAGV + L + + P TL
Sbjct: 4424 EAGVVERSMSLTLQSPPIITL 4444
Score = 73.9 bits (180), Expect = 2e-13
Identities = 56/182 (30%), Positives = 90/182 (49%), Gaps = 14/182 (7%)
Query: 72 PENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRA 131
P+ + I ++ + +P+ +SWY +G+ ++SDD H I + H+L + +
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDD-HVNIAANG--HTLQIKEAQI 2737
Query: 132 SDAGAYACVAKNRAG--EATFTVQLDVLAKEHKRAPMFIY-----KPQSKKVLEGDSVKL 184
SD G Y CVA N AG E F V + V K + ++K V+ + + L
Sbjct: 2738 SDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISL 2797
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
C+ +A PPP L W ++ + ++D++ + GRV L I +DAG YT AVNE
Sbjct: 2798 YCETNAAPPPTLTWYKDGHPLT-SSDKVLILPG--GRV-LQIPRAKVEDAGRYTCVAVNE 2853
Query: 245 AG 246
AG
Sbjct: 2854 AG 2855
Score = 72.8 bits (177), Expect = 4e-13
Identities = 56/202 (27%), Positives = 87/202 (43%), Gaps = 11/202 (5%)
Query: 75 MSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDA 134
+S EG + K SG P P V W G + + K G SL ++
Sbjct: 990 LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSA-KFSAGADG--SLYVVSPGGEES 1046
Query: 135 GAYACVAKNRAGEATFTVQLDVLAKEH---KRAPMFIYKPQSKKVLEGDSVKLECQISAI 191
G Y C A N AG A VQL V + + + KP VL G+ V L C++ ++
Sbjct: 1047 GEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSL 1106
Query: 192 PPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCN 251
PPP + W + +++ + R + + ++T + D+G Y A N AG T
Sbjct: 1107 PPPIITWAKETQLISPFSPRHTFLPSGSMKIT----ETRTSDSGMYLCVATNIAGNVTQA 1162
Query: 252 TRLDVTARPNQTLPAPKQLRVR 273
+L+V P + PK L+V+
Sbjct: 1163 VKLNVHV-PPKIQRGPKHLKVQ 1183
Score = 72.0 bits (175), Expect = 6e-13
Identities = 65/262 (24%), Positives = 108/262 (41%), Gaps = 25/262 (9%)
Query: 36 LQVPTSQVRSR-------STSRGDVNDQDAIQEKFYPPRFIQV--PENMSIDEGRFCRMD 86
L++ T+QV S+ GD +D++ + PP P ++++ R ++
Sbjct: 3584 LRISTAQVEDTGRYTCLASSPAGD-DDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLE 3642
Query: 87 FKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAG 146
K +P P ++W NG +Q+ +++ G L D Y CVA N AG
Sbjct: 3643 CKSDAVPPPVITWLRNGERLQATPRVRIL---SGGRYLQINNADLGDTANYTCVASNIAG 3699
Query: 147 EATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQ 206
+ T L V + + PQS +L S LEC +P P++ W+++ ++
Sbjct: 3700 KTTREFILTVNVPPNIKGG-----PQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLA 3754
Query: 207 FNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR-PNQTLP 265
N R S+ ++ L I+ + D G Y A N AG T R+D+ P P
Sbjct: 3755 GNHARYSILENG----FLHIQSAHVTDTGRYLCMATNAAG--TDRRRIDLQVHVPPSIAP 3808
Query: 266 APKQLRVRPTFSKYLALNGKGL 287
P + V LA G+
Sbjct: 3809 GPTNMTVIVNVQTTLACEATGI 3830
Score = 71.2 bits (173), Expect = 1e-12
Identities = 55/199 (27%), Positives = 89/199 (44%), Gaps = 13/199 (6%)
Query: 65 PPRFI---QVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGL 121
PP I + PEN+S+ E + + SG+P P ++W+ +G V + +++ G
Sbjct: 2383 PPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRIL---SGG 2439
Query: 122 HSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDS 181
L DAG Y CV +N AGE L VL H + + KV E S
Sbjct: 2440 RMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTL---EDVKVKEKQS 2496
Query: 182 VKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSA 241
V L C+++ P P++ W ++ + +Q + + +G L I +V G YT A
Sbjct: 2497 VTLTCEVTGNPVPEITWHKDGQPLQED----EAHHIISGGRFLQITNVQVPHTGRYTCLA 2552
Query: 242 VNEAGVTTCNTRLDVTARP 260
+ AG + + L+V P
Sbjct: 2553 SSPAGHKSRSFSLNVFVSP 2571
Score = 71.2 bits (173), Expect = 1e-12
Identities = 56/175 (32%), Positives = 80/175 (45%), Gaps = 16/175 (9%)
Query: 90 SGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEAT 149
SG+PAP ++W +GR + D + + G L + D G Y C+A + AG+
Sbjct: 3553 SGIPAPKMTWMKDGRPLPQTD---QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDD- 3608
Query: 150 FTVQLDVLAKEHKRAPMFIY---KPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQ 206
+ L + H P I +P+ VL V LEC+ A+PPP + W RN E +Q
Sbjct: 3609 ---DKEYLVRVH--VPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQ 3663
Query: 207 FNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPN 261
T R+ + +G L I + + D YT A N AG TT L V PN
Sbjct: 3664 -ATPRVRIL---SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPN 3714
Score = 71.2 bits (173), Expect = 1e-12
Identities = 55/197 (27%), Positives = 87/197 (44%), Gaps = 15/197 (7%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP P + + + + +G P+P ++W G V + + ++ GL
Sbjct: 3987 PPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQ-- 4044
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDS-VK 183
I VR DAG Y CVA+N AG A ++L+V + P I + V+ D +
Sbjct: 4045 ISRAVR-EDAGTYMCVAQNPAGTALGKIKLNV------QVPPVISPHLKEYVIAVDKPIT 4097
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
L C+ +PPP + W ++ + S+ Q +L I V DAG YT A N
Sbjct: 4098 LSCEADGLPPPDITWHKDGRAIV-----ESIRQRVLSSGSLQIAFVQPGDAGHYTCMAAN 4152
Query: 244 EAGVTTCNTRLDVTARP 260
AG ++ +T+L V P
Sbjct: 4153 VAGSSSTSTKLTVHVPP 4169
Score = 70.5 bits (171), Expect = 2e-12
Identities = 52/196 (26%), Positives = 78/196 (39%), Gaps = 6/196 (3%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP+ + P+++ + G+ + G P P ++W G T+ D H + + +L
Sbjct: 1170 PPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPD---GTL 1226
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
+ SDAG Y CVA N AG + L V Y ++ + ++
Sbjct: 1227 SIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEF 1286
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
C P P + W N + IS+ +D T L+I V D G Y AVNE
Sbjct: 1287 PCPAKGTPKPTIKWLHNGRELTGREPGISILEDGT---LLVIASVTPYDNGEYICVAVNE 1343
Query: 245 AGVTTCNTRLDVTARP 260
AG T L V P
Sbjct: 1344 AGTTERKYNLKVHVPP 1359
Score = 69.7 bits (169), Expect = 3e-12
Identities = 54/198 (27%), Positives = 87/198 (43%), Gaps = 16/198 (8%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP IQVP N+++ G + + +++W N R V+ + ++ + L +L
Sbjct: 519 PPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARI----RTLANL 574
Query: 125 IFEV--VRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSV 182
E+ V+ +DAG Y C+ + G + +V L V + P P+++ G V
Sbjct: 575 SLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV-----QEPPKVTVMPKNQSFTGGSEV 629
Query: 183 KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAV 242
+ C + P PK+ W N+M + R + D TL IK+ KDAG Y A
Sbjct: 630 SIMCSATGYPKPKIAW-TVNDMFIVGSHRYRMTSDG----TLFIKNAAPKDAGIYGCLAS 684
Query: 243 NEAGVTTCNTRLDVTARP 260
N AG N+ L P
Sbjct: 685 NSAGTDKQNSTLRYIEAP 702
Score = 68.9 bits (167), Expect = 5e-12
Identities = 52/183 (28%), Positives = 87/183 (47%), Gaps = 22/183 (12%)
Query: 85 MDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNR 144
+D V+G P P + W +G+ + D K++++ + L+ + S+ G Y C+A N
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGR---KLVIAQAQVSNTGLYRCMAANT 1810
Query: 145 AG------EATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFW 198
AG E T V + + + YKP V L+C + IP P + W
Sbjct: 1811 AGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKP----------VALQCIANGIPNPSITW 1860
Query: 199 KRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTA 258
++++ V NT + +L ++GRV + K + +DAG YT A N AG T + +L V
Sbjct: 1861 LKDDQPV--NTAQGNLKIQSSGRVLQIAKTL-LEDAGRYTCVATNAAGETQQHIQLHVHE 1917
Query: 259 RPN 261
P+
Sbjct: 1918 PPS 1920
Score = 68.9 bits (167), Expect = 5e-12
Identities = 50/176 (28%), Positives = 80/176 (45%), Gaps = 13/176 (7%)
Query: 88 KVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGE 147
+ GLP PD++W+ +GR + +++ S SL V+ DAG Y C+A N AG
Sbjct: 4101 EADGLPPPDITWHKDGRAIVESIRQRVLSSG----SLQIAFVQPGDAGHYTCMAANVAGS 4156
Query: 148 ATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQF 207
++ + +L V R+ Y V E L C IP P + WK++N ++
Sbjct: 4157 SSTSTKLTVHVPPRIRSTEGHYT-----VNENSQAILPCVADGIPTPAINWKKDNVLLAN 4211
Query: 208 NTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQT 263
+ + L++++V +D+G+YT A N AG T L V P T
Sbjct: 4212 LLGKYTAEPYGE----LILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFT 4263
Score = 68.6 bits (166), Expect = 7e-12
Identities = 62/202 (30%), Positives = 90/202 (44%), Gaps = 18/202 (8%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSW-YLNGRTVQSDDLHKMIVSEKGLHS 123
PP FIQ P ++S++ G + V G P P + W L+ + S +S+ +
Sbjct: 792 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851
Query: 124 LIFEVVRASDAGAYACVAKNRAG----EATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEG 179
L + ASD G Y C A+N+ G E T TV V AP+ P V+EG
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLV-------APLIGISPSVANVIEG 904
Query: 180 DSVKLECQISA-IPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
+ L C + A P P+ W +N+ M+ N I++ D +L I+ V +D G YT
Sbjct: 905 QQLTLPCTLLAGNPIPERRWIKNSAMLLQN-PYITVRSDG----SLHIERVQLQDGGEYT 959
Query: 239 VSAVNEAGVTTCNTRLDVTARP 260
A N AG T + V P
Sbjct: 960 CVASNVAGTNNKTTSVVVHVLP 981
Score = 67.4 bits (163), Expect = 2e-11
Identities = 53/180 (29%), Positives = 82/180 (45%), Gaps = 15/180 (8%)
Query: 84 RMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKN 143
+++ K +G P P ++WY + R + M +G + E + SDAG Y CVA N
Sbjct: 1939 QLECKAAGNPVPVITWYKDNRLLSGST--SMTFLNRG-QIIDIESAQISDAGIYKCVAIN 1995
Query: 144 RAG--EATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRN 201
AG E +++Q+ V AP V+ + V+LEC+ IP P L W ++
Sbjct: 1996 SAGATELFYSLQVHV-------APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKD 2048
Query: 202 NEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPN 261
V ++ + + + GR+ L + D G YT AVN AG + L V PN
Sbjct: 2049 GSPVSSFSNGLQVL--SGGRI-LALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPN 2105
Score = 67.0 bits (162), Expect = 2e-11
Identities = 46/184 (25%), Positives = 83/184 (45%), Gaps = 9/184 (4%)
Query: 65 PPRFI--QVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLH 122
PP + E++ + E + + +V+G P P+++W+ +G+ +Q D+ H +I G
Sbjct: 2477 PPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII---SGGR 2533
Query: 123 SLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSV 182
L V+ G Y C+A + AG + + L+V P+ V+
Sbjct: 2534 FLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPT 2593
Query: 183 KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAV 242
L C+ + PP + W ++ ++ N + L G TL I + + +AG Y+ A
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRIL----PGGRTLQILNAQEDNAGRYSCVAT 2649
Query: 243 NEAG 246
NEAG
Sbjct: 2650 NEAG 2653
Score = 67.0 bits (162), Expect = 2e-11
Identities = 49/174 (28%), Positives = 83/174 (47%), Gaps = 13/174 (7%)
Query: 75 MSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDA 134
+++ EG ++ + + +P P ++WY NGR + +++ + LH EV SD
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEV---SDT 3125
Query: 135 GAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLE--GDSVKLECQISAIP 192
G Y C A N AG L+V P I P+ + ++E + V L C + IP
Sbjct: 3126 GQYVCRAINVAGRDDKNFHLNVYV------PPSIEGPEREVIVETISNPVTLTCDATGIP 3179
Query: 193 PPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
PP + W +N++ ++ N+D + + + +G L I D+G YT A N G
Sbjct: 3180 PPTIAWLKNHKRIE-NSDSLEV-RILSGGSKLQIARSQHSDSGNYTCIASNMEG 3231
Score = 66.6 bits (161), Expect = 3e-11
Identities = 56/221 (25%), Positives = 92/221 (41%), Gaps = 10/221 (4%)
Query: 63 FYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLH 122
+ PP + +N+S+ + + + +P P ++W +G + L K +S
Sbjct: 2101 YVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPL----LKKPGLSISENR 2156
Query: 123 SLI-FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDS 181
S++ E + D G Y C A N AG+ +++ + + + V+EG+
Sbjct: 2157 SVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQ---LTVIEGNL 2213
Query: 182 VKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSA 241
+ L C+ S IPPP L WK+ V TD + + +G L I K DA Y+ A
Sbjct: 2214 ISLLCESSGIPPPNLIWKKKGSPVL--TDSMGRVRILSGGRQLQISIAEKSDAALYSCVA 2271
Query: 242 VNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLAL 282
N AG L V RP T + T K ++L
Sbjct: 2272 SNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISL 2312
Score = 66.2 bits (160), Expect = 3e-11
Identities = 54/185 (29%), Positives = 80/185 (43%), Gaps = 29/185 (15%)
Query: 72 PENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGL------HSLI 125
P + + G+ ++ +V G+P P V+W +G ++ KG+ H L
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHP---------LIKAKGVEILDEGHILQ 2349
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFI---YKPQSKKVLEGDSV 182
+ + SD G Y CVA N AG L V A P I P++ V+E +SV
Sbjct: 2350 LKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHA-----PPSIIGNHRSPENISVVEKNSV 2404
Query: 183 KLECQISAIPPPKLFWKRNNEMVQF-NTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSA 241
L C+ S IP P + W ++ V N+ RI +G L + +DAG YT
Sbjct: 2405 SLTCEASGIPLPSITWFKDGWPVSLSNSVRIL-----SGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 242 VNEAG 246
N AG
Sbjct: 2460 RNAAG 2464
Score = 66.2 bits (160), Expect = 3e-11
Identities = 53/204 (25%), Positives = 94/204 (46%), Gaps = 16/204 (7%)
Query: 47 STSRGDVNDQDAIQEKFYPPRFIQV--PENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGR 104
+++R V+++ + F PP E +++ +G M G PAP ++W +G+
Sbjct: 3415 ASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQ 3474
Query: 105 TVQSDDLHKMIVSEKGLHSLIFEVVRAS--DAGAYACVAKNRAGEATFTVQLDVLAKEHK 162
+ D H + + H ++ ++++A D+G Y C+A N AGE + L VL H
Sbjct: 3475 PLGLD-AHLTVST----HGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHI 3529
Query: 163 RAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRV 222
+ + V+ + ++L C S IP PK+ W ++ + TD++ Q G
Sbjct: 3530 NGS---EEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLP-QTDQV---QTLGGGE 3582
Query: 223 TLLIKDVNKKDAGWYTVSAVNEAG 246
L I +D G YT A + AG
Sbjct: 3583 VLRISTAQVEDTGRYTCLASSPAG 3606
Score = 65.5 bits (158), Expect = 6e-11
Identities = 50/175 (28%), Positives = 82/175 (46%), Gaps = 15/175 (8%)
Query: 90 SGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEAT 149
+G+P P ++W + + V + + I S + + ++ DAG Y CVA N AGE
Sbjct: 1851 NGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLE--DAGRYTCVATNAAGETQ 1908
Query: 150 FTVQLDVLAKEHKRAPMFIY---KPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQ 206
+QL H P + K ++ VL + V+LEC+ + P P + W ++N ++
Sbjct: 1909 QHIQL------HVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLS 1962
Query: 207 FNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPN 261
+T L N G++ + I+ DAG Y A+N AG T L V P+
Sbjct: 1963 GSTSMTFL---NRGQI-IDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPS 2013
Score = 64.7 bits (156), Expect = 1e-10
Identities = 48/174 (27%), Positives = 75/174 (43%), Gaps = 17/174 (9%)
Query: 89 VSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAG-- 146
++G P P+ W N + L ++ + SL E V+ D G Y CVA N AG
Sbjct: 914 LAGNPIPERRWIKNSAML----LQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTN 969
Query: 147 EATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQ 206
T +V + VL P + Q +EG V L C+ S P P + W + E++
Sbjct: 970 NKTTSVVVHVL-------PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 1022
Query: 207 FNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARP 260
++ + S D +L + +++G Y +A N AG +L V RP
Sbjct: 1023 TSSAKFSAGADG----SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRP 1072
Score = 64.3 bits (155), Expect = 1e-10
Identities = 59/221 (26%), Positives = 94/221 (42%), Gaps = 33/221 (14%)
Query: 65 PPRFI--QVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLH 122
PP I P +S+ R ++ +V G P PD+ W+ +G+ + D + ++ ++G
Sbjct: 1451 PPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELL-DRG-Q 1508
Query: 123 SLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKK------- 175
L + R +D G Y C N AG K+ K + IY P S K
Sbjct: 1509 VLHLKNARRNDKGRYQCTVSNAAG------------KQAKDIKLTIYIPPSIKGGNVTTD 1556
Query: 176 --VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKD 233
VL +KLEC+ +P P + W ++ + + ++ +LY D G+ L I D
Sbjct: 1557 ISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQ--ALYIDK-GQY-LHIPRAQVSD 1612
Query: 234 AGWYTVSAVNEAGVTTCNTRLDVTARP----NQTLPAPKQL 270
+ YT N AG + +DV P N P KQ+
Sbjct: 1613 SATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV 1653
Score = 63.9 bits (154), Expect = 2e-10
Identities = 52/193 (26%), Positives = 86/193 (44%), Gaps = 15/193 (7%)
Query: 71 VPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVR 130
V ++S+ +++ + GLP P ++WY +G+ + S + + +KG + L +
Sbjct: 1553 VTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQY-LHIPRAQ 1609
Query: 131 ASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMF---IYKPQSKKVLEGDSVKLECQ 187
SD+ Y C N AG A + +DV PM + P +K+V+ S+ LEC+
Sbjct: 1610 VSDSATYTCHVANVAGTAEKSFHVDVYV-----PPMIEGNLATPLNKQVVIAHSLTLECK 1664
Query: 188 ISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGV 247
+ P P L W ++ V+ N D I + G L I + D G Y A + AG
Sbjct: 1665 AAGNPSPILTWLKDGVPVKAN-DNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVAGE 1720
Query: 248 TTCNTRLDVTARP 260
+DV P
Sbjct: 1721 KEIKYEVDVLVPP 1733
Score = 63.2 bits (152), Expect = 3e-10
Identities = 49/179 (27%), Positives = 78/179 (43%), Gaps = 14/179 (7%)
Query: 85 MDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRA--SDAGAYACVAK 142
++ + +G P P ++W NG + +++ + + + +VRA SD Y CVA
Sbjct: 3362 IECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQ-----VIRIVRAQVSDVAVYTCVAS 3416
Query: 143 NRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNN 202
NRAG L V A + M + VL+G S + C P P + W R+
Sbjct: 3417 NRAGVDNKHYNLQVFAPPNMDNSM---GTEEITVLKGSSTSMACITDGTPAPSMAWLRDG 3473
Query: 203 EMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPN 261
+ + + L G V L+K +D+G YT A NEAG + + L V P+
Sbjct: 3474 QPLGLDAH---LTVSTHGMVLQLLK-AETEDSGKYTCIASNEAGEVSKHFILKVLEPPH 3528
Score = 62.0 bits (149), Expect = 7e-10
Identities = 54/224 (24%), Positives = 96/224 (42%), Gaps = 27/224 (12%)
Query: 36 LQVPTSQVRSRSTSRGDVNDQDAIQEK------FYPPRF---IQVPENMSIDEGRFCRMD 86
L +P +QV +T V + EK + PP + P N + ++
Sbjct: 1603 LHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLE 1662
Query: 87 FKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAG 146
K +G P+P ++W +G V+++D ++ K L + + + D G Y CVA + AG
Sbjct: 1663 CKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI---DRGQYICVATSVAG 1719
Query: 147 EATFTVQLDVLA----KEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNN 202
E ++DVL + FI V+ + ++L+C ++ PPP + W ++
Sbjct: 1720 EKEIKYEVDVLVPPAIEGGDETSYFI-------VMVNNLLELDCHVTGSPPPTIMWLKDG 1772
Query: 203 EMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAG 246
+++ +R GR L+I + G Y A N AG
Sbjct: 1773 QLID---ERDGFKILLNGR-KLVIAQAQVSNTGLYRCMAANTAG 1812
Score = 61.6 bits (148), Expect = 9e-10
Identities = 52/190 (27%), Positives = 72/190 (37%), Gaps = 14/190 (7%)
Query: 72 PENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQS-DDLHKMIVSEKGLHSLIFEVVR 130
P +S+ G + +V LP P ++W + + H + S S+ R
Sbjct: 1086 PVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPS----GSMKITETR 1141
Query: 131 ASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISA 190
SD+G Y CVA N AG T V+L+V P P+ KV G V + C
Sbjct: 1142 TSDSGMYLCVATNIAGNVTQAVKLNVHV-----PPKIQRGPKHLKVQVGQRVDIPCNAQG 1196
Query: 191 IPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTC 250
P P + W + + + + D TL I DAG YT A N AG
Sbjct: 1197 TPLPVITWSKGGSTMLVDGEHHVSNPDG----TLSIDQATPSDAGIYTCVATNIAGTDET 1252
Query: 251 NTRLDVTARP 260
L V P
Sbjct: 1253 EITLHVQEPP 1262
Score = 60.8 bits (146), Expect = 1e-09
Identities = 49/190 (25%), Positives = 84/190 (44%), Gaps = 13/190 (6%)
Query: 74 NMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS- 132
N+S+ + + +V G P+P + WY + V + + + K I ++ RA+
Sbjct: 1369 NVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGK-----ILKLFRATP 1423
Query: 133 -DAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAI 191
DAG Y+C A N AG + +DVL F P V+ V LECQ+
Sbjct: 1424 EDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNF---PNEVSVVLNRDVALECQVKGT 1480
Query: 192 PPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCN 251
P P + W ++ + + + L + G+V L +K+ + D G Y + N AG +
Sbjct: 1481 PFPDIHWFKDGKPLFLGDPNVELL--DRGQV-LHLKNARRNDKGRYQCTVSNAAGKQAKD 1537
Query: 252 TRLDVTARPN 261
+L + P+
Sbjct: 1538 IKLTIYIPPS 1547
Score = 60.8 bits (146), Expect = 1e-09
Identities = 43/197 (21%), Positives = 80/197 (40%), Gaps = 10/197 (5%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP P+++ I + ++ G+P P ++W +G + + I+ LH
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLH-- 3769
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
+ +D G Y C+A N AG + L V P P + V+ L
Sbjct: 3770 -IQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVP-----PSIAPGPTNMTVIVNVQTTL 3823
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
C+ + IP P + W++N ++ + ++ S ++G + ++ V+ D Y + N
Sbjct: 3824 ACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVD--DTATYECTVTNG 3881
Query: 245 AGVTTCNTRLDVTARPN 261
AG L V P+
Sbjct: 3882 AGDDKRTVDLTVQVPPS 3898
Score = 60.5 bits (145), Expect = 2e-09
Identities = 49/183 (26%), Positives = 78/183 (42%), Gaps = 15/183 (8%)
Query: 65 PPRFI-QVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS 123
PP F P N G ++ +V G P P + W N + V + H+ + + G S
Sbjct: 4348 PPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQW--NRKGVDIEISHR--IRQLGNGS 4403
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
L DAG Y CVA N AG ++ L + + P+ +P + G +
Sbjct: 4404 LAIYGTVNEDAGDYTCVATNEAGVVERSMSLTL-----QSPPIITLEPVETVINAGGKII 4458
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
L CQ + P P + W R + ++ DR+++ +N +L I D K+D + A N
Sbjct: 4459 LNCQATGEPQPTITWSRQGHSISWD-DRVNVLSNN----SLYIADAQKEDTSEFECVARN 4513
Query: 244 EAG 246
G
Sbjct: 4514 LMG 4516
Score = 59.3 bits (142), Expect = 4e-09
Identities = 51/197 (25%), Positives = 84/197 (42%), Gaps = 14/197 (7%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNG-RTVQSDDLHKMIVSEKGLHS 123
PP P + + + + SG+P P + W NG R + D ++++ S +
Sbjct: 3896 PPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSG----A 3951
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
+ + + AG Y CVA+N AG A V L V P+ +P V+ + +
Sbjct: 3952 IEILATQLNHAGRYTCVARNAAGSAHRHVTLHV-----HEPPVIQPQPSELHVILNNPIL 4006
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
L C+ + P P + W++ E + NT + +G L I ++DAG Y A N
Sbjct: 4007 LPCEATGTPSPFITWQK--EGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQN 4062
Query: 244 EAGVTTCNTRLDVTARP 260
AG +L+V P
Sbjct: 4063 PAGTALGKIKLNVQVPP 4079
Score = 58.9 bits (141), Expect = 6e-09
Identities = 54/188 (28%), Positives = 84/188 (44%), Gaps = 14/188 (7%)
Query: 88 KVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRAS--DAGAYACVAKNRA 145
+ + P P ++WY +G + S D K+++ G + ++ RA DAG Y CVA N A
Sbjct: 2800 ETNAAPPPTLTWYKDGHPLTSSD--KVLILPGGR---VLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 146 GEATFTVQLDVLAKE-HKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEM 204
GE + + VL K A + P+ VL S +EC S P P+ W+++ +
Sbjct: 2855 GEDSLQYDVRVLVPPIIKGANSDL--PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQP 2912
Query: 205 VQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTL 264
+ + L + GR+ L I + D G Y A N AG L+V P+
Sbjct: 2913 LLEDDHHKFL---SNGRI-LQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIG 2968
Query: 265 PAPKQLRV 272
P + L V
Sbjct: 2969 PKSENLTV 2976
Score = 55.1 bits (131), Expect = 8e-08
Identities = 44/178 (24%), Positives = 82/178 (46%), Gaps = 22/178 (12%)
Query: 93 PAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTV 152
P ++W+ +G ++S+ +++ + L L + +AG Y+CVA N AGE
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILPGGRTLQILN---AQEDNAGRYSCVATNEAGEMIKHY 2659
Query: 153 QLDVLAKEHKRAPMFIYK---------PQSKKVLEGDSVKLECQISAIPPPKLFWKRNNE 203
++ V P I K P+ K+ +++ LEC+ AIP L W ++ +
Sbjct: 2660 EVKVY------IPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQ 2713
Query: 204 MVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPN 261
++ + D +++ + TL IK+ D G YT A N AG + +++ P+
Sbjct: 2714 PLK-SDDHVNIAANGH---TLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPS 2767
Score = 47.8 bits (112), Expect = 1e-05
Identities = 48/174 (27%), Positives = 67/174 (38%), Gaps = 14/174 (8%)
Query: 97 VSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDV 156
+S+ NG T+ D K E +L V SD G Y C+A + AG DV
Sbjct: 461 LSFVRNGVTLGVDQYLK----ESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDV 516
Query: 157 LAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQF-NTDRISLY 215
P I P + V G+ L C I + L W+RN+ V+ RI
Sbjct: 517 -----SEPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIR-- 569
Query: 216 QDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQ 269
++L +K V DAG Y +E G + + L V P T+ Q
Sbjct: 570 --TLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQ 621
Score = 36.2 bits (82), Expect = 0.039
Identities = 23/97 (23%), Positives = 44/97 (45%), Gaps = 6/97 (6%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP P I+ G ++ + +G P P ++W G ++ DD ++ + +SL
Sbjct: 4439 PPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSN----NSL 4494
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEH 161
+ D + CVA+N G + V++ V+ + H
Sbjct: 4495 YIADAQKEDTSEFECVARNLMG--SVLVRVPVIVQVH 4529
Score = 34.3 bits (77), Expect = 0.15
Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 6/92 (6%)
Query: 183 KLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAV 242
++ C + ++ P L + RN V D+ Y + V L I V D G+Y AV
Sbjct: 448 QIPCSVDSLLPFTLSFVRNG--VTLGVDQ---YLKESASVNLDIAKVTLSDEGFYECIAV 502
Query: 243 NEAGVTTCNTRLDVTARPNQTLPAPKQLRVRP 274
+ AG T DV + P + P + V P
Sbjct: 503 SSAGTGRAQTFFDV-SEPPPVIQVPNNVTVTP 533
>gi|61888896 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2b [Homo sapiens]
Length = 1378
Score = 86.3 bits (212), Expect = 3e-17
Identities = 56/202 (27%), Positives = 97/202 (48%), Gaps = 21/202 (10%)
Query: 55 DQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD---- 110
D ++++ +PPR ++ P ++ + +G ++ K G P P + WY +G V++D
Sbjct: 20 DGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPR 79
Query: 111 LHKMIVSEKGLHSLIFEVVRAS--DAGAYACVAKNRAGEA---TFTVQLDVLAKEHKRAP 165
H+M++ L L R S D G+Y CVA+N GEA ++++ +L + ++ P
Sbjct: 80 SHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNP 139
Query: 166 MFIYKPQSKKVLEGDSVKLECQ-ISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTL 224
+ V G+ LECQ P P ++WK++ + +RIS+ L
Sbjct: 140 TDVV------VAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGK-----L 188
Query: 225 LIKDVNKKDAGWYTVSAVNEAG 246
+I + K DAG YT N G
Sbjct: 189 MISNTRKSDAGMYTCVGTNMVG 210
Score = 75.5 bits (184), Expect = 6e-14
Identities = 64/245 (26%), Positives = 110/245 (44%), Gaps = 26/245 (10%)
Query: 51 GDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD 110
G+ + A F P F++ P N + E +V G P P V W + D
Sbjct: 210 GERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDA-----D 264
Query: 111 LHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYK 170
L + K ++L + ++D G Y C+A+NR G+ + L V A P F+ +
Sbjct: 265 LPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAP-----PQFVVR 319
Query: 171 PQSKKVLEGDSVKLECQISAIPPPKLFWKRN--------NEMVQFNTDRISLYQDNTGRV 222
P+ + V +G +V C+ P P +FW++ N+ Q N+ R S+ TG +
Sbjct: 320 PRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNS-RCSV--SPTGDL 376
Query: 223 TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLAL 282
T I ++ + DAG+Y A+ AG +L+VT + P + ++ ++ LA+
Sbjct: 377 T--ITNIQRSDAGYYICQALTVAGSILAKAQLEVT---DVLTDRPPPIILQGPANQTLAV 431
Query: 283 NGKGL 287
+G L
Sbjct: 432 DGTAL 436
Score = 66.6 bits (161), Expect = 3e-11
Identities = 56/185 (30%), Positives = 79/185 (42%), Gaps = 24/185 (12%)
Query: 91 GLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEA-T 149
G P P + W + V+ DD + I G L+ R SDAG Y CV N GE +
Sbjct: 159 GHPEPTIYWKKD--KVRIDDKEERISIRGG--KLMISNTRKSDAGMYTCVGTNMVGERDS 214
Query: 150 FTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNT 209
+L V + P F+ +P ++ VLE ++V+ CQ+ P P + WK+++
Sbjct: 215 DPAELTVFER-----PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDD--ADLPR 267
Query: 210 DRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQ 269
R + D TL IK D G Y A N G + L T+ AP Q
Sbjct: 268 GRYDIKDD----YTLRIKKTMSTDEGTYMCIAENRVGKMEASATL--------TVRAPPQ 315
Query: 270 LRVRP 274
VRP
Sbjct: 316 FVVRP 320
Score = 66.2 bits (160), Expect = 3e-11
Identities = 54/200 (27%), Positives = 81/200 (40%), Gaps = 13/200 (6%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGR------TVQSDDLHKMIVSE 118
PP+F+ P + + +GR + G P P V W G + VS
Sbjct: 313 PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSP 372
Query: 119 KGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLE 178
G L ++ SDAG Y C A AG QL+V R P I + + + L
Sbjct: 373 TG--DLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLA 430
Query: 179 GDSVKL-ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
D L +C+ + P P + W + R ++ + T L IK++ D G Y
Sbjct: 431 VDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGT----LQIKNLRISDTGTY 486
Query: 238 TVSAVNEAGVTTCNTRLDVT 257
T A + +G T+ + LDVT
Sbjct: 487 TCVATSSSGETSWSAVLDVT 506
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 85.1 bits (209), Expect = 7e-17
Identities = 55/198 (27%), Positives = 96/198 (48%), Gaps = 21/198 (10%)
Query: 59 IQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD----LHKM 114
++++ +PPR ++ P ++ + +G ++ K G P P + WY +G V++D H+M
Sbjct: 40 LRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRM 99
Query: 115 IVSEKGLHSLIFEVVRAS--DAGAYACVAKNRAGEA---TFTVQLDVLAKEHKRAPMFIY 169
++ L L R S D G+Y CVA+N GEA ++++ +L + ++ P +
Sbjct: 100 LLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVV 159
Query: 170 KPQSKKVLEGDSVKLECQ-ISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKD 228
V G+ LECQ P P ++WK++ + +RIS+ L+I +
Sbjct: 160 ------VAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGK-----LMISN 208
Query: 229 VNKKDAGWYTVSAVNEAG 246
K DAG YT N G
Sbjct: 209 TRKSDAGMYTCVGTNMVG 226
Score = 75.5 bits (184), Expect = 6e-14
Identities = 64/245 (26%), Positives = 110/245 (44%), Gaps = 26/245 (10%)
Query: 51 GDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD 110
G+ + A F P F++ P N + E +V G P P V W + D
Sbjct: 226 GERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDA-----D 280
Query: 111 LHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYK 170
L + K ++L + ++D G Y C+A+NR G+ + L V A P F+ +
Sbjct: 281 LPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAP-----PQFVVR 335
Query: 171 PQSKKVLEGDSVKLECQISAIPPPKLFWKRN--------NEMVQFNTDRISLYQDNTGRV 222
P+ + V +G +V C+ P P +FW++ N+ Q N+ R S+ TG +
Sbjct: 336 PRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNS-RCSV--SPTGDL 392
Query: 223 TLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKYLAL 282
T I ++ + DAG+Y A+ AG +L+VT + P + ++ ++ LA+
Sbjct: 393 T--ITNIQRSDAGYYICQALTVAGSILAKAQLEVT---DVLTDRPPPIILQGPANQTLAV 447
Query: 283 NGKGL 287
+G L
Sbjct: 448 DGTAL 452
Score = 66.6 bits (161), Expect = 3e-11
Identities = 56/185 (30%), Positives = 79/185 (42%), Gaps = 24/185 (12%)
Query: 91 GLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEA-T 149
G P P + W + V+ DD + I G L+ R SDAG Y CV N GE +
Sbjct: 175 GHPEPTIYWKKD--KVRIDDKEERISIRGG--KLMISNTRKSDAGMYTCVGTNMVGERDS 230
Query: 150 FTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNT 209
+L V + P F+ +P ++ VLE ++V+ CQ+ P P + WK+++
Sbjct: 231 DPAELTVFER-----PTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDD--ADLPR 283
Query: 210 DRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQ 269
R + D TL IK D G Y A N G + L T+ AP Q
Sbjct: 284 GRYDIKDD----YTLRIKKTMSTDEGTYMCIAENRVGKMEASATL--------TVRAPPQ 331
Query: 270 LRVRP 274
VRP
Sbjct: 332 FVVRP 336
Score = 66.2 bits (160), Expect = 3e-11
Identities = 54/200 (27%), Positives = 81/200 (40%), Gaps = 13/200 (6%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGR------TVQSDDLHKMIVSE 118
PP+F+ P + + +GR + G P P V W G + VS
Sbjct: 329 PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSP 388
Query: 119 KGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLE 178
G L ++ SDAG Y C A AG QL+V R P I + + + L
Sbjct: 389 TG--DLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLA 446
Query: 179 GDSVKL-ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 237
D L +C+ + P P + W + R ++ + T L IK++ D G Y
Sbjct: 447 VDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGT----LQIKNLRISDTGTY 502
Query: 238 TVSAVNEAGVTTCNTRLDVT 257
T A + +G T+ + LDVT
Sbjct: 503 TCVATSSSGETSWSAVLDVT 522
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 84.7 bits (208), Expect = 1e-16
Identities = 56/206 (27%), Positives = 95/206 (46%), Gaps = 11/206 (5%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
PR P+++ + G + G P P++ W N ++ +D ++ V + G +L+
Sbjct: 234 PRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDDG--TLM 291
Query: 126 FEVVRASDAGAYACVAKNRAGEA-TFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
R SD G Y C+A+N AGEA T + L + K P F+ +PQ +VL G S L
Sbjct: 292 IRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAK--PSFVIQPQDTEVLIGTSTTL 349
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
EC + P P + W R+N + + ++ L ++++ ++D G +T A N
Sbjct: 350 ECMATGHPHPLITWTRDNGLELDGSRHVATSSG------LYLQNITQRDHGRFTCHANNS 403
Query: 245 AGVTTCNTRLDVTARPNQTLPAPKQL 270
G + V A P T+ Q+
Sbjct: 404 HGTVQAAANIIVQAPPQFTVTPKDQV 429
Score = 64.7 bits (156), Expect = 1e-10
Identities = 55/194 (28%), Positives = 79/194 (40%), Gaps = 12/194 (6%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 124
PP+F P++ + E + G P P + W G + + H ++ S +L
Sbjct: 418 PPQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHTVLSSG----TL 473
Query: 125 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 184
+ D G Y C A + G +VQL V + K +F PQ V G ++ +
Sbjct: 474 RIDRAAQHDQGQYECQAVSSLGVKKVSVQLTV---KPKALAVFTQLPQDTSVEVGKNINI 530
Query: 185 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
C P P + W N E VQ T+ + D+ G TL I D D G Y A N
Sbjct: 531 SCHAQGEPQPIITW--NKEGVQI-TESGKFHVDDEG--TLTIYDAGFPDQGRYECVARNS 585
Query: 245 AGVTTCNTRLDVTA 258
G+ N L VTA
Sbjct: 586 FGLAVTNMFLTVTA 599
Score = 54.7 bits (130), Expect = 1e-07
Identities = 44/191 (23%), Positives = 73/191 (38%), Gaps = 15/191 (7%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F+ P++ + G ++ +G P P ++W + H + + GL+
Sbjct: 330 PSFVIQPQDTEVLIGTSTTLECMATGHPHPLITWTRDNGLELDGSRH--VATSSGLY--- 384
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLE 185
+ + D G + C A N G + V A P F P+ + VLE +V+
Sbjct: 385 LQNITQRDHGRFTCHANNSHGTVQAAANIIVQAP-----PQFTVTPKDQVVLEEHAVEWL 439
Query: 186 CQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEA 245
C+ PPP + W + + L TL I + D G Y AV+
Sbjct: 440 CEADGNPPPVIVWTKTGGQLPVEGQHTVLSSG-----TLRIDRAAQHDQGQYECQAVSSL 494
Query: 246 GVTTCNTRLDV 256
GV + +L V
Sbjct: 495 GVKKVSVQLTV 505
Score = 50.1 bits (118), Expect = 3e-06
Identities = 25/85 (29%), Positives = 44/85 (51%), Gaps = 5/85 (5%)
Query: 163 RAPMFIYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTD-RISLYQDNTGR 221
++P ++PQ +V G++V C+ P P++ W NN + D R++++ D
Sbjct: 232 QSPRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDDG--- 288
Query: 222 VTLLIKDVNKKDAGWYTVSAVNEAG 246
TL+I++ + D G Y A N AG
Sbjct: 289 -TLMIRNTRESDQGVYQCMARNSAG 312
Score = 43.5 bits (101), Expect = 2e-04
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 4/97 (4%)
Query: 68 FIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFE 127
F Q+P++ S++ G+ + G P P ++W N VQ + K V ++G +L
Sbjct: 513 FTQLPQDTSVEVGKNINISCHAQGEPQPIITW--NKEGVQITESGKFHVDDEG--TLTIY 568
Query: 128 VVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRA 164
D G Y CVA+N G A + L V A + ++A
Sbjct: 569 DAGFPDQGRYECVARNSFGLAVTNMFLTVTAIQGRQA 605
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 84.0 bits (206), Expect = 2e-16
Identities = 57/203 (28%), Positives = 92/203 (45%), Gaps = 15/203 (7%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
PR P++ + G + G P P++ W N + ++ + + G +L+
Sbjct: 246 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDG--TLM 303
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLE 185
+ + +D G Y C+AKN AGE T ++ + P F+ +PQ+ +VL G+SV LE
Sbjct: 304 IQNTQETDQGIYQCMAKNVAGEVK-TQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLE 362
Query: 186 CQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVT----LLIKDVNKKDAGWYTVSA 241
C + PPP++ W R DR L D +T L I++V + D+G Y SA
Sbjct: 363 CSATGHPPPRISWTRG--------DRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSA 414
Query: 242 VNEAGVTTCNTRLDVTARPNQTL 264
N + V A P T+
Sbjct: 415 TNNIDSVHATAFIIVQALPQFTV 437
Score = 76.3 bits (186), Expect = 3e-14
Identities = 62/212 (29%), Positives = 84/212 (39%), Gaps = 16/212 (7%)
Query: 51 GDVNDQDAIQEKFYPPR---FIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQ 107
G+V Q+ F P F+ P+N + G ++ +G P P +SW RT
Sbjct: 324 GEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPL 383
Query: 108 SDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMF 167
D I GL+ + V D+G YAC A N T + V A P F
Sbjct: 384 PVDPRVNITPSGGLY---IQNVVQGDSGEYACSATNNIDSVHATAFIIVQA-----LPQF 435
Query: 168 IYKPQSKKVLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIK 227
PQ + V+EG +V +C+ PPP + W + Q + DR L + TL I
Sbjct: 436 TVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGS--QLSVDRRHLVLSSG---TLRIS 490
Query: 228 DVNKKDAGWYTVSAVNEAGVTTCNTRLDVTAR 259
V D G Y AVN G L V R
Sbjct: 491 GVALHDQGQYECQAVNIIGSQKVVAHLTVQPR 522
Score = 61.6 bits (148), Expect = 9e-10
Identities = 51/191 (26%), Positives = 76/191 (39%), Gaps = 12/191 (6%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P+F P++ + EG+ + G P P ++W G + D H ++ S +L
Sbjct: 433 PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSG----TLR 488
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLE 185
V D G Y C A N G L V + + P+F P V G +V+L
Sbjct: 489 ISGVALHDQGQYECQAVNIIGSQKVVAHLTV---QPRVTPVFASIPSDTTVEVGANVQLP 545
Query: 186 CQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEA 245
C P P + W ++ V T+ + G +T I DV DAG Y A N
Sbjct: 546 CSSQGEPEPAITWNKDGVQV---TESGKFHISPEGFLT--INDVGPADAGRYECVARNTI 600
Query: 246 GVTTCNTRLDV 256
G + + L V
Sbjct: 601 GSASVSMVLSV 611
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 81.6 bits (200), Expect = 8e-16
Identities = 57/212 (26%), Positives = 96/212 (45%), Gaps = 8/212 (3%)
Query: 65 PPRFIQVPE-NMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS 123
PP+F++ PE +++ + + + + G+P P ++WY + V+ + L + G
Sbjct: 307 PPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDG--G 364
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
L + D G + C A+N AGE + L V + AP P V++G SV
Sbjct: 365 LQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSI----APNITRGPLDSTVIDGMSVV 420
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
L C+ S P P + W++ ++ + ++ + +LLI + DAG YT A N
Sbjct: 421 LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESG-SLLISPTHISDAGTYTCLATN 479
Query: 244 EAGVTTCNTRLDVTARPNQTLPAPKQLRVRPT 275
GV + L V AR T P Q ++ T
Sbjct: 480 SRGVDEASADLVVWARTRITKPPQDQSVIKGT 511
Score = 54.3 bits (129), Expect = 1e-07
Identities = 49/214 (22%), Positives = 85/214 (39%), Gaps = 12/214 (5%)
Query: 51 GDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD 110
G+V + P + P + ++ +G + + SG P P ++W R + S
Sbjct: 387 GEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGS 446
Query: 111 LHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYK 170
+ + SL+ SDAG Y C+A N G + L V A+ P
Sbjct: 447 VQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKP----- 501
Query: 171 PQSKKVLEGDSVKLECQISAIP--PPKLFWKRNNEMVQFNT-DRISLYQDNTGRVTLLIK 227
PQ + V++G + C ++ P + W+++ + + RI L D G +L I
Sbjct: 502 PQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRL--DRNG--SLHIS 557
Query: 228 DVNKKDAGWYTVSAVNEAGVTTCNTRLDVTARPN 261
D G YT ++ G + + L V P+
Sbjct: 558 QTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPH 591
Score = 45.8 bits (107), Expect = 5e-05
Identities = 45/164 (27%), Positives = 70/164 (42%), Gaps = 21/164 (12%)
Query: 88 KVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGE 147
+++ P P V+W+ +GR + + + ++L+ A DAG Y A N
Sbjct: 136 RIASFPQPQVTWFRDGRKIPPSSRIAITLE----NTLVILSTVAPDAGRYYVQAVNDKNG 191
Query: 148 ATFTVQLDVLAKEH------KRAPMFIYKPQSKKVLEGDS-VKLECQISAIPPPKL--FW 198
T Q L E+ AP I P++ V+ G S V LEC +A P KL W
Sbjct: 192 DNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIW 251
Query: 199 KRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAV 242
K++ ++ D+ R+T I + DAG+Y AV
Sbjct: 252 KKDGVLLSGG------ISDHNRRLT--IPNPTGSDAGYYECEAV 287
Score = 37.4 bits (85), Expect = 0.017
Identities = 32/112 (28%), Positives = 54/112 (48%), Gaps = 10/112 (8%)
Query: 134 AGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLEC-QISAIP 192
AG Y C+ +NR G A Q +V + F + + V G++ + +I++ P
Sbjct: 86 AGFYRCIVRNRMG-ALLQRQTEV---QVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFP 141
Query: 193 PPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNE 244
P++ W R+ + + RI++ +NT L+I DAG Y V AVN+
Sbjct: 142 QPQVTWFRDGRKIP-PSSRIAITLENT----LVILSTVAPDAGRYYVQAVND 188
>gi|169217528 PREDICTED: similar to sidekick homolog 2 (chicken)
[Homo sapiens]
Length = 399
Score = 81.6 bits (200), Expect = 8e-16
Identities = 57/212 (26%), Positives = 96/212 (45%), Gaps = 8/212 (3%)
Query: 65 PPRFIQVPE-NMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHS 123
PP+F++ PE +++ + + + + G+P P ++WY + V+ + L + G
Sbjct: 119 PPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDG--G 176
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
L + D G + C A+N AGE + L V + AP P V++G SV
Sbjct: 177 LQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSI----APNITRGPLDSTVIDGMSVV 232
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
L C+ S P P + W++ ++ + ++ + +LLI + DAG YT A N
Sbjct: 233 LACETSGAPRPAITWQKGERILASGSVQLPRFTPLESG-SLLISPTHISDAGTYTCLATN 291
Query: 244 EAGVTTCNTRLDVTARPNQTLPAPKQLRVRPT 275
GV + L V AR T P Q ++ T
Sbjct: 292 SRGVDEASADLVVWARTRITKPPQDQSVIKGT 323
Score = 49.3 bits (116), Expect = 4e-06
Identities = 33/142 (23%), Positives = 57/142 (40%), Gaps = 5/142 (3%)
Query: 51 GDVNDQDAIQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD 110
G+V + P + P + ++ +G + + SG P P ++W R + S
Sbjct: 199 GEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGS 258
Query: 111 LHKMIVSEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYK 170
+ + SL+ SDAG Y C+A N G + L V A+ P
Sbjct: 259 VQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKP----- 313
Query: 171 PQSKKVLEGDSVKLECQISAIP 192
PQ + V++G + C ++ P
Sbjct: 314 PQDQSVIKGTQASMVCGVTHDP 335
>gi|40255157 leucine-rich repeats and immunoglobulin-like domains 3
isoform 2 [Homo sapiens]
Length = 1119
Score = 81.6 bits (200), Expect = 8e-16
Identities = 57/202 (28%), Positives = 91/202 (45%), Gaps = 13/202 (6%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRT--VQSDDLHKMIVSEKGLHS 123
P F + P +++I G R++ G PAP ++W +G T + + ++ E +
Sbjct: 603 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 662
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
++ V+ D G Y+C A+N AG + L VL P F+ + V +G++
Sbjct: 663 IV--DVKIEDIGVYSCTAQNSAGSISANATLTVL-----ETPSFLRPLLDRTVTKGETAV 715
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
L+C PPPKL W +++ + T+R + G L+I D + DAG YT N
Sbjct: 716 LQCIAGGSPPPKLNWTKDDSPLVV-TER---HFFAAGNQLLIIVDSDVSDAGKYTCEMSN 771
Query: 244 EAGVTTCNTRLDVTARPNQTLP 265
G N RL V P P
Sbjct: 772 TLGTERGNVRLSVIPTPTCDSP 793
>gi|209862903 leucine-rich repeats and immunoglobulin-like domains 3
isoform 1 [Homo sapiens]
Length = 1059
Score = 81.6 bits (200), Expect = 8e-16
Identities = 57/202 (28%), Positives = 91/202 (45%), Gaps = 13/202 (6%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRT--VQSDDLHKMIVSEKGLHS 123
P F + P +++I G R++ G PAP ++W +G T + + ++ E +
Sbjct: 543 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 602
Query: 124 LIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVK 183
++ V+ D G Y+C A+N AG + L VL P F+ + V +G++
Sbjct: 603 IV--DVKIEDIGVYSCTAQNSAGSISANATLTVL-----ETPSFLRPLLDRTVTKGETAV 655
Query: 184 LECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVN 243
L+C PPPKL W +++ + T+R + G L+I D + DAG YT N
Sbjct: 656 LQCIAGGSPPPKLNWTKDDSPLVV-TER---HFFAAGNQLLIIVDSDVSDAGKYTCEMSN 711
Query: 244 EAGVTTCNTRLDVTARPNQTLP 265
G N RL V P P
Sbjct: 712 TLGTERGNVRLSVIPTPTCDSP 733
>gi|19743806 roundabout 1 isoform b [Homo sapiens]
Length = 1612
Score = 81.3 bits (199), Expect = 1e-15
Identities = 57/199 (28%), Positives = 92/199 (46%), Gaps = 21/199 (10%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F++ P N+++ + G P P V W + +L K + H+L
Sbjct: 223 PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKD-----DGELPKSRYEIRDDHTLK 277
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLE 185
V A D G+Y CVA+N G+A + L V + P F+ KP+ + V G +V +
Sbjct: 278 IRKVTAGDMGSYTCVAENMVGKAEASATLTV-----QEPPHFVVKPRDQVVALGRTVTFQ 332
Query: 186 CQISAIPPPKLFWKR---NNEMVQF----NTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
C+ + P P +FW+R N + + ++ R S+ Q TG +T I +V + D G+Y
Sbjct: 333 CEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ--TGDLT--ITNVQRSDVGYYI 388
Query: 239 VSAVNEAGVTTCNTRLDVT 257
+N AG L+VT
Sbjct: 389 CQTLNVAGSIITKAYLEVT 407
Score = 77.8 bits (190), Expect = 1e-14
Identities = 57/214 (26%), Positives = 94/214 (43%), Gaps = 22/214 (10%)
Query: 59 IQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD----LHKM 114
++++ +PPR ++ P ++ + +G ++ K G P P + WY G V++D H+M
Sbjct: 22 LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRM 81
Query: 115 IVSEKGLHSLIFEVVRAS--DAGAYACVAKNRAGEA---TFTVQLDVLAKEHKRAPMFIY 169
++ L L R S D G Y CVA+N GEA ++++ +L + F
Sbjct: 82 LLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD------FRQ 135
Query: 170 KPQSKKVLEGDSVKLECQ-ISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKD 228
P V G+ +ECQ P P + WK++ + +RI++ L+I
Sbjct: 136 NPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK-----LMITY 190
Query: 229 VNKKDAGWYTVSAVNEAGVTTCN-TRLDVTARPN 261
K DAG Y N G L V RP+
Sbjct: 191 TRKSDAGKYVCVGTNMVGERESEVAELTVLERPS 224
Score = 68.6 bits (166), Expect = 7e-12
Identities = 57/196 (29%), Positives = 86/196 (43%), Gaps = 17/196 (8%)
Query: 68 FIQVPENMSIDEGRFCRMDFKVS-GLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIF 126
F Q P ++ + G M+ + G P P +SW +G + DD + I G L+
Sbjct: 133 FRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPL--DDKDERITIRGG--KLMI 188
Query: 127 EVVRASDAGAYACVAKNRAGEATFTV-QLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLE 185
R SDAG Y CV N GE V +L VL + P F+ +P + V DS + +
Sbjct: 189 TYTRKSDAGKYVCVGTNMVGERESEVAELTVLER-----PSFVKRPSNLAVTVDDSAEFK 243
Query: 186 CQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEA 245
C+ P P + W++++ + R + D+T L I+ V D G YT A N
Sbjct: 244 CEARGDPVPTVRWRKDDG--ELPKSRYEIRDDHT----LKIRKVTAGDMGSYTCVAENMV 297
Query: 246 GVTTCNTRLDVTARPN 261
G + L V P+
Sbjct: 298 GKAEASATLTVQEPPH 313
Score = 58.2 bits (139), Expect = 1e-08
Identities = 51/201 (25%), Positives = 79/201 (39%), Gaps = 17/201 (8%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNG--------RTVQSDDLHKMIV 116
PP F+ P + + GR + +G P P + W G + QS + V
Sbjct: 311 PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSS--RFSV 368
Query: 117 SEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYK-PQSKK 175
S+ G L V+ SD G Y C N AG L+V R P I + P ++
Sbjct: 369 SQTG--DLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQT 426
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V + L C + P P + W+++ +V RI ++ L I+ D G
Sbjct: 427 VAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG----VLQIRYAKLGDTG 482
Query: 236 WYTVSAVNEAGVTTCNTRLDV 256
YT A +G T + ++V
Sbjct: 483 RYTCIASTPSGEATWSAYIEV 503
>gi|4506569 roundabout 1 isoform a [Homo sapiens]
Length = 1651
Score = 81.3 bits (199), Expect = 1e-15
Identities = 57/199 (28%), Positives = 92/199 (46%), Gaps = 21/199 (10%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F++ P N+++ + G P P V W + +L K + H+L
Sbjct: 262 PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKD-----DGELPKSRYEIRDDHTLK 316
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLE 185
V A D G+Y CVA+N G+A + L V + P F+ KP+ + V G +V +
Sbjct: 317 IRKVTAGDMGSYTCVAENMVGKAEASATLTV-----QEPPHFVVKPRDQVVALGRTVTFQ 371
Query: 186 CQISAIPPPKLFWKR---NNEMVQF----NTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
C+ + P P +FW+R N + + ++ R S+ Q TG +T I +V + D G+Y
Sbjct: 372 CEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ--TGDLT--ITNVQRSDVGYYI 427
Query: 239 VSAVNEAGVTTCNTRLDVT 257
+N AG L+VT
Sbjct: 428 CQTLNVAGSIITKAYLEVT 446
Score = 77.8 bits (190), Expect = 1e-14
Identities = 57/214 (26%), Positives = 94/214 (43%), Gaps = 22/214 (10%)
Query: 59 IQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD----LHKM 114
++++ +PPR ++ P ++ + +G ++ K G P P + WY G V++D H+M
Sbjct: 61 LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRM 120
Query: 115 IVSEKGLHSLIFEVVRAS--DAGAYACVAKNRAGEA---TFTVQLDVLAKEHKRAPMFIY 169
++ L L R S D G Y CVA+N GEA ++++ +L + F
Sbjct: 121 LLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD------FRQ 174
Query: 170 KPQSKKVLEGDSVKLECQ-ISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKD 228
P V G+ +ECQ P P + WK++ + +RI++ L+I
Sbjct: 175 NPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK-----LMITY 229
Query: 229 VNKKDAGWYTVSAVNEAGVTTCN-TRLDVTARPN 261
K DAG Y N G L V RP+
Sbjct: 230 TRKSDAGKYVCVGTNMVGERESEVAELTVLERPS 263
Score = 68.6 bits (166), Expect = 7e-12
Identities = 57/196 (29%), Positives = 86/196 (43%), Gaps = 17/196 (8%)
Query: 68 FIQVPENMSIDEGRFCRMDFKVS-GLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIF 126
F Q P ++ + G M+ + G P P +SW +G + DD + I G L+
Sbjct: 172 FRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPL--DDKDERITIRGG--KLMI 227
Query: 127 EVVRASDAGAYACVAKNRAGEATFTV-QLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLE 185
R SDAG Y CV N GE V +L VL + P F+ +P + V DS + +
Sbjct: 228 TYTRKSDAGKYVCVGTNMVGERESEVAELTVLER-----PSFVKRPSNLAVTVDDSAEFK 282
Query: 186 CQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEA 245
C+ P P + W++++ + R + D+T L I+ V D G YT A N
Sbjct: 283 CEARGDPVPTVRWRKDDG--ELPKSRYEIRDDHT----LKIRKVTAGDMGSYTCVAENMV 336
Query: 246 GVTTCNTRLDVTARPN 261
G + L V P+
Sbjct: 337 GKAEASATLTVQEPPH 352
Score = 58.2 bits (139), Expect = 1e-08
Identities = 51/201 (25%), Positives = 79/201 (39%), Gaps = 17/201 (8%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNG--------RTVQSDDLHKMIV 116
PP F+ P + + GR + +G P P + W G + QS + V
Sbjct: 350 PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSS--RFSV 407
Query: 117 SEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYK-PQSKK 175
S+ G L V+ SD G Y C N AG L+V R P I + P ++
Sbjct: 408 SQTG--DLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQT 465
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V + L C + P P + W+++ +V RI ++ L I+ D G
Sbjct: 466 VAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG----VLQIRYAKLGDTG 521
Query: 236 WYTVSAVNEAGVTTCNTRLDV 256
YT A +G T + ++V
Sbjct: 522 RYTCIASTPSGEATWSAYIEV 542
>gi|224994173 roundabout 1 isoform d [Homo sapiens]
Length = 1551
Score = 80.9 bits (198), Expect = 1e-15
Identities = 57/199 (28%), Positives = 92/199 (46%), Gaps = 18/199 (9%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F++ P N+++ + G P P V W + +L K + H+L
Sbjct: 223 PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKD-----DGELPKSRYEIRDDHTLK 277
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLE 185
V A D G+Y CVA+N G+A + L V + P F+ KP+ + V G +V +
Sbjct: 278 IRKVTAGDMGSYTCVAENMVGKAEASATLTV--QVGSEPPHFVVKPRDQVVALGRTVTFQ 335
Query: 186 CQISAIPPPKLFWKR---NNEMVQF----NTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
C+ + P P +FW+R N + + ++ R S+ Q TG +T I +V + D G+Y
Sbjct: 336 CEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ--TGDLT--ITNVQRSDVGYYI 391
Query: 239 VSAVNEAGVTTCNTRLDVT 257
+N AG L+VT
Sbjct: 392 CQTLNVAGSIITKAYLEVT 410
Score = 77.8 bits (190), Expect = 1e-14
Identities = 57/214 (26%), Positives = 94/214 (43%), Gaps = 22/214 (10%)
Query: 59 IQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD----LHKM 114
++++ +PPR ++ P ++ + +G ++ K G P P + WY G V++D H+M
Sbjct: 22 LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRM 81
Query: 115 IVSEKGLHSLIFEVVRAS--DAGAYACVAKNRAGEA---TFTVQLDVLAKEHKRAPMFIY 169
++ L L R S D G Y CVA+N GEA ++++ +L + F
Sbjct: 82 LLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD------FRQ 135
Query: 170 KPQSKKVLEGDSVKLECQ-ISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKD 228
P V G+ +ECQ P P + WK++ + +RI++ L+I
Sbjct: 136 NPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK-----LMITY 190
Query: 229 VNKKDAGWYTVSAVNEAGVTTCN-TRLDVTARPN 261
K DAG Y N G L V RP+
Sbjct: 191 TRKSDAGKYVCVGTNMVGERESEVAELTVLERPS 224
Score = 58.2 bits (139), Expect = 1e-08
Identities = 51/201 (25%), Positives = 79/201 (39%), Gaps = 17/201 (8%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNG--------RTVQSDDLHKMIV 116
PP F+ P + + GR + +G P P + W G + QS + V
Sbjct: 314 PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSS--RFSV 371
Query: 117 SEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYK-PQSKK 175
S+ G L V+ SD G Y C N AG L+V R P I + P ++
Sbjct: 372 SQTG--DLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQT 429
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V + L C + P P + W+++ +V RI ++ L I+ D G
Sbjct: 430 VAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG----VLQIRYAKLGDTG 485
Query: 236 WYTVSAVNEAGVTTCNTRLDV 256
YT A +G T + ++V
Sbjct: 486 RYTCIASTPSGEATWSAYIEV 506
>gi|224994171 roundabout 1 isoform c [Homo sapiens]
Length = 1606
Score = 80.9 bits (198), Expect = 1e-15
Identities = 57/199 (28%), Positives = 92/199 (46%), Gaps = 18/199 (9%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F++ P N+++ + G P P V W + +L K + H+L
Sbjct: 223 PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKD-----DGELPKSRYEIRDDHTLK 277
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLE 185
V A D G+Y CVA+N G+A + L V + P F+ KP+ + V G +V +
Sbjct: 278 IRKVTAGDMGSYTCVAENMVGKAEASATLTV--QVGSEPPHFVVKPRDQVVALGRTVTFQ 335
Query: 186 CQISAIPPPKLFWKR---NNEMVQF----NTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
C+ + P P +FW+R N + + ++ R S+ Q TG +T I +V + D G+Y
Sbjct: 336 CEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ--TGDLT--ITNVQRSDVGYYI 391
Query: 239 VSAVNEAGVTTCNTRLDVT 257
+N AG L+VT
Sbjct: 392 CQTLNVAGSIITKAYLEVT 410
Score = 77.8 bits (190), Expect = 1e-14
Identities = 57/214 (26%), Positives = 94/214 (43%), Gaps = 22/214 (10%)
Query: 59 IQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD----LHKM 114
++++ +PPR ++ P ++ + +G ++ K G P P + WY G V++D H+M
Sbjct: 22 LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRM 81
Query: 115 IVSEKGLHSLIFEVVRAS--DAGAYACVAKNRAGEA---TFTVQLDVLAKEHKRAPMFIY 169
++ L L R S D G Y CVA+N GEA ++++ +L + F
Sbjct: 82 LLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD------FRQ 135
Query: 170 KPQSKKVLEGDSVKLECQ-ISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKD 228
P V G+ +ECQ P P + WK++ + +RI++ L+I
Sbjct: 136 NPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK-----LMITY 190
Query: 229 VNKKDAGWYTVSAVNEAGVTTCN-TRLDVTARPN 261
K DAG Y N G L V RP+
Sbjct: 191 TRKSDAGKYVCVGTNMVGERESEVAELTVLERPS 224
Score = 58.2 bits (139), Expect = 1e-08
Identities = 51/201 (25%), Positives = 79/201 (39%), Gaps = 17/201 (8%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNG--------RTVQSDDLHKMIV 116
PP F+ P + + GR + +G P P + W G + QS + V
Sbjct: 314 PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSS--RFSV 371
Query: 117 SEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYK-PQSKK 175
S+ G L V+ SD G Y C N AG L+V R P I + P ++
Sbjct: 372 SQTG--DLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQT 429
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V + L C + P P + W+++ +V RI ++ L I+ D G
Sbjct: 430 VAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG----VLQIRYAKLGDTG 485
Query: 236 WYTVSAVNEAGVTTCNTRLDV 256
YT A +G T + ++V
Sbjct: 486 RYTCIASTPSGEATWSAYIEV 506
>gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo
sapiens]
Length = 1562
Score = 80.9 bits (198), Expect = 1e-15
Identities = 57/199 (28%), Positives = 92/199 (46%), Gaps = 18/199 (9%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F++ P N+++ + G P P V W + +L K + H+L
Sbjct: 223 PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKD-----DGELPKSRYEIRDDHTLK 277
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLE 185
V A D G+Y CVA+N G+A + L V + P F+ KP+ + V G +V +
Sbjct: 278 IRKVTAGDMGSYTCVAENMVGKAEASATLTV--QVGSEPPHFVVKPRDQVVALGRTVTFQ 335
Query: 186 CQISAIPPPKLFWKR---NNEMVQF----NTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
C+ + P P +FW+R N + + ++ R S+ Q TG +T I +V + D G+Y
Sbjct: 336 CEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ--TGDLT--ITNVQRSDVGYYI 391
Query: 239 VSAVNEAGVTTCNTRLDVT 257
+N AG L+VT
Sbjct: 392 CQTLNVAGSIITKAYLEVT 410
Score = 77.8 bits (190), Expect = 1e-14
Identities = 57/214 (26%), Positives = 94/214 (43%), Gaps = 22/214 (10%)
Query: 59 IQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD----LHKM 114
++++ +PPR ++ P ++ + +G ++ K G P P + WY G V++D H+M
Sbjct: 22 LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRM 81
Query: 115 IVSEKGLHSLIFEVVRAS--DAGAYACVAKNRAGEA---TFTVQLDVLAKEHKRAPMFIY 169
++ L L R S D G Y CVA+N GEA ++++ +L + F
Sbjct: 82 LLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD------FRQ 135
Query: 170 KPQSKKVLEGDSVKLECQ-ISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKD 228
P V G+ +ECQ P P + WK++ + +RI++ L+I
Sbjct: 136 NPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK-----LMITY 190
Query: 229 VNKKDAGWYTVSAVNEAGVTTCN-TRLDVTARPN 261
K DAG Y N G L V RP+
Sbjct: 191 TRKSDAGKYVCVGTNMVGERESEVAELTVLERPS 224
Score = 58.2 bits (139), Expect = 1e-08
Identities = 51/201 (25%), Positives = 79/201 (39%), Gaps = 17/201 (8%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNG--------RTVQSDDLHKMIV 116
PP F+ P + + GR + +G P P + W G + QS + V
Sbjct: 314 PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSS--RFSV 371
Query: 117 SEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYK-PQSKK 175
S+ G L V+ SD G Y C N AG L+V R P I + P ++
Sbjct: 372 SQTG--DLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQT 429
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V + L C + P P + W+++ +V RI ++ L I+ D G
Sbjct: 430 VAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG----VLQIRYAKLGDTG 485
Query: 236 WYTVSAVNEAGVTTCNTRLDV 256
YT A +G T + ++V
Sbjct: 486 RYTCIASTPSGEATWSAYIEV 506
>gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo
sapiens]
Length = 1615
Score = 80.9 bits (198), Expect = 1e-15
Identities = 57/199 (28%), Positives = 92/199 (46%), Gaps = 18/199 (9%)
Query: 66 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 125
P F++ P N+++ + G P P V W + +L K + H+L
Sbjct: 223 PSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKD-----DGELPKSRYEIRDDHTLK 277
Query: 126 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKLE 185
V A D G+Y CVA+N G+A + L V + P F+ KP+ + V G +V +
Sbjct: 278 IRKVTAGDMGSYTCVAENMVGKAEASATLTV--QVGSEPPHFVVKPRDQVVALGRTVTFQ 335
Query: 186 CQISAIPPPKLFWKR---NNEMVQF----NTDRISLYQDNTGRVTLLIKDVNKKDAGWYT 238
C+ + P P +FW+R N + + ++ R S+ Q TG +T I +V + D G+Y
Sbjct: 336 CEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQ--TGDLT--ITNVQRSDVGYYI 391
Query: 239 VSAVNEAGVTTCNTRLDVT 257
+N AG L+VT
Sbjct: 392 CQTLNVAGSIITKAYLEVT 410
Score = 77.8 bits (190), Expect = 1e-14
Identities = 57/214 (26%), Positives = 94/214 (43%), Gaps = 22/214 (10%)
Query: 59 IQEKFYPPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDD----LHKM 114
++++ +PPR ++ P ++ + +G ++ K G P P + WY G V++D H+M
Sbjct: 22 LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRM 81
Query: 115 IVSEKGLHSLIFEVVRAS--DAGAYACVAKNRAGEA---TFTVQLDVLAKEHKRAPMFIY 169
++ L L R S D G Y CVA+N GEA ++++ +L + F
Sbjct: 82 LLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD------FRQ 135
Query: 170 KPQSKKVLEGDSVKLECQ-ISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKD 228
P V G+ +ECQ P P + WK++ + +RI++ L+I
Sbjct: 136 NPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK-----LMITY 190
Query: 229 VNKKDAGWYTVSAVNEAGVTTCN-TRLDVTARPN 261
K DAG Y N G L V RP+
Sbjct: 191 TRKSDAGKYVCVGTNMVGERESEVAELTVLERPS 224
Score = 58.2 bits (139), Expect = 1e-08
Identities = 51/201 (25%), Positives = 79/201 (39%), Gaps = 17/201 (8%)
Query: 65 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNG--------RTVQSDDLHKMIV 116
PP F+ P + + GR + +G P P + W G + QS + V
Sbjct: 314 PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSS--RFSV 371
Query: 117 SEKGLHSLIFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYK-PQSKK 175
S+ G L V+ SD G Y C N AG L+V R P I + P ++
Sbjct: 372 SQTG--DLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQT 429
Query: 176 VLEGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAG 235
V + L C + P P + W+++ +V RI ++ L I+ D G
Sbjct: 430 VAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENG----VLQIRYAKLGDTG 485
Query: 236 WYTVSAVNEAGVTTCNTRLDV 256
YT A +G T + ++V
Sbjct: 486 RYTCIASTPSGEATWSAYIEV 506
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,738,797
Number of Sequences: 37866
Number of extensions: 503269
Number of successful extensions: 5070
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 220
Number of HSP's successfully gapped in prelim test: 128
Number of HSP's that attempted gapping in prelim test: 1390
Number of HSP's gapped (non-prelim): 1937
length of query: 314
length of database: 18,247,518
effective HSP length: 102
effective length of query: 212
effective length of database: 14,385,186
effective search space: 3049659432
effective search space used: 3049659432
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.