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Search of human proteins with 206725530
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|206725530 FK506 binding protein 2, 13kDa precursor [Homo
sapiens]
(142 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|206725530 FK506 binding protein 2, 13kDa precursor [Homo sapi... 289 5e-79
gi|17149844 FK506 binding protein 2, 13kDa precursor [Homo sapiens] 289 5e-79
gi|17149842 FK506 binding protein 2, 13kDa precursor [Homo sapiens] 289 5e-79
gi|192448443 FK506 binding protein 10 [Homo sapiens] 100 7e-22
gi|224809331 FK506 binding protein 5 isoform 2 [Homo sapiens] 99 9e-22
gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens] 99 9e-22
gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens] 99 9e-22
gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens] 99 9e-22
gi|206725547 FK506 binding protein 7 isoform b precursor [Homo s... 99 1e-21
gi|33469985 FK506 binding protein 9 [Homo sapiens] 99 2e-21
gi|8923659 FK506 binding protein 14 [Homo sapiens] 98 2e-21
gi|7706131 FK506 binding protein 11 isoform 1 precursor [Homo sa... 98 3e-21
gi|31317231 FK506 binding protein 7 isoform a precursor [Homo sa... 97 6e-21
gi|17149836 FK506 binding protein 1A, 12kDa [Homo sapiens] 97 6e-21
gi|4503725 FK506 binding protein 1A, 12kDa [Homo sapiens] 97 6e-21
gi|4503727 FK506 binding protein 3, 25kDa [Homo sapiens] 93 8e-20
gi|4503729 FK506 binding protein 52 [Homo sapiens] 92 2e-19
gi|219842220 FK506 binding protein 11 isoform 3 precursor [Homo ... 91 4e-19
gi|4758380 FK506 binding protein 1B, 12.6 kDa isoform a [Homo sa... 88 3e-18
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens] 61 4e-10
gi|219842217 FK506 binding protein 11 isoform 2 [Homo sapiens] 54 4e-08
gi|206725544 FK506 binding protein 6 isoform b [Homo sapiens] 54 6e-08
gi|146229346 FK506 binding protein 6 isoform a [Homo sapiens] 54 6e-08
gi|17149839 FK506 binding protein 1B, 12.6 kDa isoform b [Homo s... 53 7e-08
gi|52630440 FK506-binding protein 8 [Homo sapiens] 40 5e-04
gi|83779010 SECIS binding protein 2 [Homo sapiens] 29 1.1
gi|51172610 Rho guanine nucleotide exchange factor (GEF) 5-like ... 28 2.0
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 28 2.0
gi|51230412 GTPase activating Rap/RanGAP domain-like 1 isoform 2... 28 2.6
gi|51226124 GTPase activating Rap/RanGAP domain-like 1 isoform 1... 28 2.6
>gi|206725530 FK506 binding protein 2, 13kDa precursor [Homo
sapiens]
Length = 142
Score = 289 bits (740), Expect = 5e-79
Identities = 142/142 (100%), Positives = 142/142 (100%)
Query: 1 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL 60
MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL
Sbjct: 1 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL 60
Query: 61 EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK 120
EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK
Sbjct: 61 EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK 120
Query: 121 IPGGATLVFEVELLKIERRTEL 142
IPGGATLVFEVELLKIERRTEL
Sbjct: 121 IPGGATLVFEVELLKIERRTEL 142
>gi|17149844 FK506 binding protein 2, 13kDa precursor [Homo sapiens]
Length = 142
Score = 289 bits (740), Expect = 5e-79
Identities = 142/142 (100%), Positives = 142/142 (100%)
Query: 1 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL 60
MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL
Sbjct: 1 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL 60
Query: 61 EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK 120
EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK
Sbjct: 61 EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK 120
Query: 121 IPGGATLVFEVELLKIERRTEL 142
IPGGATLVFEVELLKIERRTEL
Sbjct: 121 IPGGATLVFEVELLKIERRTEL 142
>gi|17149842 FK506 binding protein 2, 13kDa precursor [Homo sapiens]
Length = 142
Score = 289 bits (740), Expect = 5e-79
Identities = 142/142 (100%), Positives = 142/142 (100%)
Query: 1 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL 60
MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL
Sbjct: 1 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL 60
Query: 61 EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK 120
EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK
Sbjct: 61 EDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPK 120
Query: 121 IPGGATLVFEVELLKIERRTEL 142
IPGGATLVFEVELLKIERRTEL
Sbjct: 121 IPGGATLVFEVELLKIERRTEL 142
>gi|192448443 FK506 binding protein 10 [Homo sapiens]
Length = 582
Score = 99.8 bits (247), Expect = 7e-22
Identities = 49/106 (46%), Positives = 66/106 (62%)
Query: 31 LQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWD 90
+Q+ R HCP + GD + HY G L DGT FD+S + + +G+G +IKG D
Sbjct: 156 VQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVGSGWLIKGMD 215
Query: 91 QGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKI 136
QGLLGMC GE+RK++IP L YGE+G IP A+LVF V L+ +
Sbjct: 216 QGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLIDV 261
Score = 93.2 bits (230), Expect = 6e-20
Identities = 43/93 (46%), Positives = 56/93 (60%)
Query: 42 CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEK 101
C ++ GD + HY G L DGT FDSS +N + +G G +I G DQGL G C GE+
Sbjct: 279 CVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQGYIIPGMDQGLQGACMGER 338
Query: 102 RKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
R++ IP L YGE G KIPG A L+F V ++
Sbjct: 339 RRITIPPHLAYGENGTGDKIPGSAVLIFNVHVI 371
Score = 92.4 bits (228), Expect = 1e-19
Identities = 43/95 (45%), Positives = 59/95 (62%)
Query: 42 CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEK 101
CP + + GD + HY G EDG +FDSS +N +G G++I G D+GL+GMC E+
Sbjct: 55 CPREVQMGDFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNER 114
Query: 102 RKLVIPSELGYGERGAPPKIPGGATLVFEVELLKI 136
R+L++P LGYG G IP ATL F+V LL +
Sbjct: 115 RRLIVPPHLGYGSIGLAGLIPPDATLYFDVVLLDV 149
Score = 80.1 bits (196), Expect = 6e-16
Identities = 42/96 (43%), Positives = 58/96 (60%), Gaps = 1/96 (1%)
Query: 42 CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEK 101
C ++ GD + HY L DGT+ +S P +LG +VI+G D GL GMC GE+
Sbjct: 392 CNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATLGANKVIEGLDTGLQGMCVGER 451
Query: 102 RKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIE 137
R+L++P L +GE GA +PG A L+FEVEL+ E
Sbjct: 452 RQLIVPPHLAHGESGA-RGVPGSAVLLFEVELVSRE 486
>gi|224809331 FK506 binding protein 5 isoform 2 [Homo sapiens]
Length = 268
Score = 99.4 bits (246), Expect = 9e-22
Identities = 51/100 (51%), Positives = 65/100 (65%)
Query: 35 VKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLL 94
+ KRV + GD +++HY GKL +G +FDSS +N+PFVFSLG GQVIK WD G+
Sbjct: 36 IVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVA 95
Query: 95 GMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
M +GE L+ E YG G+ PKIP ATL FE+ELL
Sbjct: 96 TMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135
>gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 99.4 bits (246), Expect = 9e-22
Identities = 51/100 (51%), Positives = 65/100 (65%)
Query: 35 VKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLL 94
+ KRV + GD +++HY GKL +G +FDSS +N+PFVFSLG GQVIK WD G+
Sbjct: 36 IVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVA 95
Query: 95 GMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
M +GE L+ E YG G+ PKIP ATL FE+ELL
Sbjct: 96 TMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135
Score = 30.8 bits (68), Expect = 0.39
Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 10/98 (10%)
Query: 48 KGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQ---VIKGWDQGLLGMCEGEKRKL 104
+G + +H G+ G FD + F++G G+ + G D+ L M E+ L
Sbjct: 164 EGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPIGIDKALEKMQREEQCIL 217
Query: 105 VIPSELGYGERGAPP-KIPGGATLVFEVELLKIERRTE 141
+ G+GE G P I A L++EV L E+ E
Sbjct: 218 YLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKE 255
>gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 99.4 bits (246), Expect = 9e-22
Identities = 51/100 (51%), Positives = 65/100 (65%)
Query: 35 VKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLL 94
+ KRV + GD +++HY GKL +G +FDSS +N+PFVFSLG GQVIK WD G+
Sbjct: 36 IVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVA 95
Query: 95 GMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
M +GE L+ E YG G+ PKIP ATL FE+ELL
Sbjct: 96 TMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135
Score = 30.8 bits (68), Expect = 0.39
Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 10/98 (10%)
Query: 48 KGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQ---VIKGWDQGLLGMCEGEKRKL 104
+G + +H G+ G FD + F++G G+ + G D+ L M E+ L
Sbjct: 164 EGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPIGIDKALEKMQREEQCIL 217
Query: 105 VIPSELGYGERGAPP-KIPGGATLVFEVELLKIERRTE 141
+ G+GE G P I A L++EV L E+ E
Sbjct: 218 YLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKE 255
>gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 99.4 bits (246), Expect = 9e-22
Identities = 51/100 (51%), Positives = 65/100 (65%)
Query: 35 VKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLL 94
+ KRV + GD +++HY GKL +G +FDSS +N+PFVFSLG GQVIK WD G+
Sbjct: 36 IVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVA 95
Query: 95 GMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
M +GE L+ E YG G+ PKIP ATL FE+ELL
Sbjct: 96 TMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELL 135
Score = 30.8 bits (68), Expect = 0.39
Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 10/98 (10%)
Query: 48 KGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQ---VIKGWDQGLLGMCEGEKRKL 104
+G + +H G+ G FD + F++G G+ + G D+ L M E+ L
Sbjct: 164 EGATVEIHLEGRC-GGRMFDC-----RDVAFTVGEGEDHDIPIGIDKALEKMQREEQCIL 217
Query: 105 VIPSELGYGERGAPP-KIPGGATLVFEVELLKIERRTE 141
+ G+GE G P I A L++EV L E+ E
Sbjct: 218 YLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKE 255
>gi|206725547 FK506 binding protein 7 isoform b precursor [Homo
sapiens]
Length = 221
Score = 99.0 bits (245), Expect = 1e-21
Identities = 54/116 (46%), Positives = 73/116 (62%), Gaps = 3/116 (2%)
Query: 26 EGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL-EDGTEFDSSLPQNQ--PFVFSLGT 82
E +++I V R ++C S+KGD+L+ HY G L +DG++F S QN+ P F LG
Sbjct: 30 ESTEEVKIEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGV 89
Query: 83 GQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIER 138
GQVIKG D + MC GEKRK+VIP YG+ G KIP ATL+FE+EL + +
Sbjct: 90 GQVIKGLDIAMTDMCPGEKRKVVIPPSFAYGKEGYEGKIPPDATLIFEIELYAVTK 145
>gi|33469985 FK506 binding protein 9 [Homo sapiens]
Length = 570
Score = 98.6 bits (244), Expect = 2e-21
Identities = 51/107 (47%), Positives = 69/107 (64%), Gaps = 3/107 (2%)
Query: 30 KLQIGVKKRV--DHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIK 87
K I ++ +V ++C S+ GD L HY G L DGT FDSS +N+ F +G G VI
Sbjct: 257 KDSISIENKVVPENCERISQSGDFLRYHYNGTLLDGTLFDSSYSRNRTFDTYIGQGYVIP 316
Query: 88 GWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
G D+GLLG+C GEKR++V+P LGYGE G IPG A LVF++ ++
Sbjct: 317 GMDEGLLGVCIGEKRRIVVPPHLGYGEEGR-GNIPGSAVLVFDIHVI 362
Score = 97.8 bits (242), Expect = 3e-21
Identities = 46/95 (48%), Positives = 61/95 (64%)
Query: 42 CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEK 101
C + S+KGD L HY L DGT DS+ + + LG+GQV+ G D GL MC GEK
Sbjct: 382 CSVLSKKGDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGSGQVVLGMDMGLREMCVGEK 441
Query: 102 RKLVIPSELGYGERGAPPKIPGGATLVFEVELLKI 136
R ++IP LGYGE G ++PG A LVF++ELL++
Sbjct: 442 RTVIIPPHLGYGEAGVDGEVPGSAVLVFDIELLEL 476
Score = 87.8 bits (216), Expect = 3e-18
Identities = 49/129 (37%), Positives = 66/129 (51%)
Query: 8 VLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFD 67
+L +L A G +LQI + D CP R GD + HY G DG +FD
Sbjct: 13 LLLLLLWVTGQAAPVAGLGSDAELQIERRFVPDECPRTVRSGDFVRYHYVGTFPDGQKFD 72
Query: 68 SSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATL 127
SS ++ F +G GQ+I G DQ L+GMC E+R + IP +L YG G IP + L
Sbjct: 73 SSYDRDSTFNVFVGKGQLITGMDQALVGMCVNERRFVKIPPKLAYGNEGVSGVIPPNSVL 132
Query: 128 VFEVELLKI 136
F+V L+ I
Sbjct: 133 HFDVLLMDI 141
Score = 85.5 bits (210), Expect = 1e-17
Identities = 47/107 (43%), Positives = 62/107 (57%)
Query: 30 KLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGW 89
++QI + CP + D + HY G DGT FDSS + + + +G G +I G
Sbjct: 147 QVQIHTYFKPPSCPRTIQVSDFVRYHYNGTFLDGTLFDSSHNRMKTYDTYVGIGWLIPGM 206
Query: 90 DQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKI 136
D+GLLGMC GEKR + IP L YGE G IPG A+LVF+V LL +
Sbjct: 207 DKGLLGMCVGEKRIITIPPFLAYGEDGDGKDIPGQASLVFDVALLDL 253
>gi|8923659 FK506 binding protein 14 [Homo sapiens]
Length = 211
Score = 98.2 bits (243), Expect = 2e-21
Identities = 57/129 (44%), Positives = 85/129 (65%), Gaps = 6/129 (4%)
Query: 11 VLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLE-DGTEFDSS 69
VL++ ++++ A E + K+++ K + C K++ GD++ +HY G LE DG+ F S+
Sbjct: 9 VLTLFVTSLIGALIPEPEVKIEVLQKPFI--CHRKTKGGDLMLVHYEGYLEKDGSLFHST 66
Query: 70 LPQN--QPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATL 127
N QP F+LG + +KGWDQGL GMC GEKRKL+IP LGYG+ G KIP +TL
Sbjct: 67 HKHNNGQPIWFTLGILEALKGWDQGLKGMCVGEKRKLIIPPALGYGKEG-KGKIPPESTL 125
Query: 128 VFEVELLKI 136
+F ++LL+I
Sbjct: 126 IFNIDLLEI 134
>gi|7706131 FK506 binding protein 11 isoform 1 precursor [Homo
sapiens]
Length = 201
Score = 97.8 bits (242), Expect = 3e-21
Identities = 48/97 (49%), Positives = 63/97 (64%), Gaps = 1/97 (1%)
Query: 42 CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEK 101
C + GD LH+HYTG L DG D+SL ++ P V LG QVI G +Q LL MC GEK
Sbjct: 50 CAEPAAFGDTLHIHYTGSLVDGRIIDTSLTRD-PLVIELGQKQVIPGLEQSLLDMCVGEK 108
Query: 102 RKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIER 138
R+ +IPS L YG+RG PP +P A + ++VEL+ + R
Sbjct: 109 RRAIIPSHLAYGKRGFPPSVPADAVVQYDVELIALIR 145
>gi|31317231 FK506 binding protein 7 isoform a precursor [Homo
sapiens]
Length = 222
Score = 96.7 bits (239), Expect = 6e-21
Identities = 55/117 (47%), Positives = 74/117 (63%), Gaps = 4/117 (3%)
Query: 26 EGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKL-EDGTEFDSSLPQNQ--PFVFSLGT 82
E +++I V R ++C S+KGD+L+ HY G L +DG++F S QN+ P F LG
Sbjct: 30 ESTEEVKIEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGV 89
Query: 83 GQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERG-APPKIPGGATLVFEVELLKIER 138
GQVIKG D + MC GEKRK+VIP YG+ G A KIP ATL+FE+EL + +
Sbjct: 90 GQVIKGLDIAMTDMCPGEKRKVVIPPSFAYGKEGYAEGKIPPDATLIFEIELYAVTK 146
>gi|17149836 FK506 binding protein 1A, 12kDa [Homo sapiens]
Length = 108
Score = 96.7 bits (239), Expect = 6e-21
Identities = 46/91 (50%), Positives = 62/91 (68%)
Query: 47 RKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVI 106
++G +HYTG LEDG +FDSS +N+PF F LG +VI+GW++G+ M G++ KL I
Sbjct: 18 KRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTI 77
Query: 107 PSELGYGERGAPPKIPGGATLVFEVELLKIE 137
+ YG G P IP ATLVF+VELLK+E
Sbjct: 78 SPDYAYGATGHPGIIPPHATLVFDVELLKLE 108
>gi|4503725 FK506 binding protein 1A, 12kDa [Homo sapiens]
Length = 108
Score = 96.7 bits (239), Expect = 6e-21
Identities = 46/91 (50%), Positives = 62/91 (68%)
Query: 47 RKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVI 106
++G +HYTG LEDG +FDSS +N+PF F LG +VI+GW++G+ M G++ KL I
Sbjct: 18 KRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTI 77
Query: 107 PSELGYGERGAPPKIPGGATLVFEVELLKIE 137
+ YG G P IP ATLVF+VELLK+E
Sbjct: 78 SPDYAYGATGHPGIIPPHATLVFDVELLKLE 108
>gi|4503727 FK506 binding protein 3, 25kDa [Homo sapiens]
Length = 224
Score = 92.8 bits (229), Expect = 8e-20
Identities = 53/120 (44%), Positives = 72/120 (60%), Gaps = 9/120 (7%)
Query: 26 EGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQN-------QPFVF 78
EG K V K+ D +KGDV+H YTG L+DGT FD+++ + +P F
Sbjct: 106 EGPPKYTKSVLKKGDKTNFP-KKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSF 164
Query: 79 SLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAP-PKIPGGATLVFEVELLKIE 137
+G G+VI+GWD+ LL M +GEK +L I E YG++G P KIP A L FEVEL+ I+
Sbjct: 165 KVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID 224
>gi|4503729 FK506 binding protein 52 [Homo sapiens]
Length = 459
Score = 91.7 bits (226), Expect = 2e-19
Identities = 46/89 (51%), Positives = 56/89 (62%)
Query: 49 GDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPS 108
GD + +HYTG L DGT+FDSSL + F F LG G+VIK WD + M GE +
Sbjct: 50 GDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKP 109
Query: 109 ELGYGERGAPPKIPGGATLVFEVELLKIE 137
E YG G+PPKIP ATLVFEVEL + +
Sbjct: 110 EYAYGSAGSPPKIPPNATLVFEVELFEFK 138
>gi|219842220 FK506 binding protein 11 isoform 3 precursor [Homo
sapiens]
Length = 146
Score = 90.5 bits (223), Expect = 4e-19
Identities = 44/82 (53%), Positives = 54/82 (65%), Gaps = 1/82 (1%)
Query: 42 CPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEK 101
C + GD LH+HYTG L DG D+SL ++ P V LG QVI G +Q LL MC GEK
Sbjct: 50 CAEPAAFGDTLHIHYTGSLVDGRIIDTSLTRD-PLVIELGQKQVIPGLEQSLLDMCVGEK 108
Query: 102 RKLVIPSELGYGERGAPPKIPG 123
R+ +IPS L YG+RG PP +PG
Sbjct: 109 RRAIIPSHLAYGKRGFPPSVPG 130
>gi|4758380 FK506 binding protein 1B, 12.6 kDa isoform a [Homo
sapiens]
Length = 108
Score = 87.8 bits (216), Expect = 3e-18
Identities = 41/91 (45%), Positives = 60/91 (65%)
Query: 47 RKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVI 106
+KG +HYTG L++G +FDSS +N+PF F +G +VIKG+++G M G++ KL
Sbjct: 18 KKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQMSLGQRAKLTC 77
Query: 107 PSELGYGERGAPPKIPGGATLVFEVELLKIE 137
++ YG G P IP ATL+F+VELL +E
Sbjct: 78 TPDVAYGATGHPGVIPPNATLIFDVELLNLE 108
>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
Length = 1219
Score = 60.8 bits (146), Expect = 4e-10
Identities = 36/94 (38%), Positives = 53/94 (56%), Gaps = 5/94 (5%)
Query: 49 GDVLHMHYTGKLED----GTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKL 104
GD L + YTG L G FDS+ +++ LG+G+VIKGW+ G+LGM +G KR L
Sbjct: 197 GDSLEVAYTGWLFQNHVLGQVFDSTANKDKLLRLKLGSGKVIKGWEDGMLGMKKGGKRLL 256
Query: 105 VIPSELGYGERGAPPKIPG-GATLVFEVELLKIE 137
++P G G + LVFEVE+ +++
Sbjct: 257 IVPPACAVGSEGVIGWTQATDSILVFEVEVRRVK 290
>gi|219842217 FK506 binding protein 11 isoform 2 [Homo sapiens]
Length = 99
Score = 53.9 bits (128), Expect = 4e-08
Identities = 22/43 (51%), Positives = 31/43 (72%)
Query: 96 MCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELLKIER 138
MC GEKR+ +IPS L YG+RG PP +P A + ++VEL+ + R
Sbjct: 1 MCVGEKRRAIIPSHLAYGKRGFPPSVPADAVVQYDVELIALIR 43
>gi|206725544 FK506 binding protein 6 isoform b [Homo sapiens]
Length = 322
Score = 53.5 bits (127), Expect = 6e-08
Identities = 37/114 (32%), Positives = 54/114 (47%), Gaps = 7/114 (6%)
Query: 28 KRKLQIGVKKRVDHCPIKSRKGDVLH------MHYTGKLED-GTEFDSSLPQNQPFVFSL 80
+R L I + V I+ GD++ + Y+G LE FDS+ + P + L
Sbjct: 22 QRMLDISGDRGVLKDVIREGAGDLVAPDASVLVKYSGYLEHMDRPFDSNYFRKTPRLMKL 81
Query: 81 GTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
G + G + GLL M GE + + YG G PP IP T++FE+ELL
Sbjct: 82 GEDITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPPLIPPNTTVLFEIELL 135
>gi|146229346 FK506 binding protein 6 isoform a [Homo sapiens]
Length = 327
Score = 53.5 bits (127), Expect = 6e-08
Identities = 37/114 (32%), Positives = 54/114 (47%), Gaps = 7/114 (6%)
Query: 28 KRKLQIGVKKRVDHCPIKSRKGDVLH------MHYTGKLED-GTEFDSSLPQNQPFVFSL 80
+R L I + V I+ GD++ + Y+G LE FDS+ + P + L
Sbjct: 27 QRMLDISGDRGVLKDVIREGAGDLVAPDASVLVKYSGYLEHMDRPFDSNYFRKTPRLMKL 86
Query: 81 GTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVELL 134
G + G + GLL M GE + + YG G PP IP T++FE+ELL
Sbjct: 87 GEDITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPPLIPPNTTVLFEIELL 140
>gi|17149839 FK506 binding protein 1B, 12.6 kDa isoform b [Homo
sapiens]
Length = 80
Score = 53.1 bits (126), Expect = 7e-08
Identities = 22/46 (47%), Positives = 34/46 (73%)
Query: 47 RKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQG 92
+KG +HYTG L++G +FDSS +N+PF F +G +VIKG+++G
Sbjct: 18 KKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEG 63
>gi|52630440 FK506-binding protein 8 [Homo sapiens]
Length = 413
Score = 40.4 bits (93), Expect = 5e-04
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 7/88 (7%)
Query: 48 KGDVLHMHYTGKLEDGTEFDSSLPQNQP-FVFSLGTGQVIKGWDQGLLGMCEGEKRKLVI 106
KG V+ +H LE+GT Q +P VF+LG VI+ D + M GE +
Sbjct: 119 KGQVVTVHLQTSLENGTRV-----QEEPELVFTLGDCDVIQALDLSVPLMDVGETAMVTA 173
Query: 107 PSELGYGERGA-PPKIPGGATLVFEVEL 133
S+ YG +G+ P IP A L EV L
Sbjct: 174 DSKYCYGPQGSRSPYIPPHAALCLEVTL 201
>gi|83779010 SECIS binding protein 2 [Homo sapiens]
Length = 854
Score = 29.3 bits (64), Expect = 1.1
Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 7/63 (11%)
Query: 25 AEGKRKLQIGVKKRVDHCPIKSRKGDVLH-----MHYTGKLEDG--TEFDSSLPQNQPFV 77
A+ KR+L +G+++ + H +K K ++ + G L+D T D + QN PFV
Sbjct: 667 AKTKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFV 726
Query: 78 FSL 80
F+L
Sbjct: 727 FAL 729
>gi|51172610 Rho guanine nucleotide exchange factor (GEF) 5-like
[Homo sapiens]
Length = 484
Score = 28.5 bits (62), Expect = 2.0
Identities = 34/129 (26%), Positives = 49/129 (37%), Gaps = 20/129 (15%)
Query: 24 GAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTG 83
G E KR+LQ+ + R D KS+ TGK ED + +P +G
Sbjct: 323 GEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPV---------SG 373
Query: 84 QVIK---GWDQGLLGMC--------EGEKRKLVIPSELGYGERGAPPKIPGGATLVFEVE 132
Q K WD G LG E E +P+ + + PG + LV ++
Sbjct: 374 QEAKEPESWDGGRLGAVGRARSREEENEHHGPSMPALIAPEDSPHCDLFPGASYLVTQIP 433
Query: 133 LLKIERRTE 141
+ E R E
Sbjct: 434 GTQTESRAE 442
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 28.5 bits (62), Expect = 2.0
Identities = 18/69 (26%), Positives = 32/69 (46%), Gaps = 6/69 (8%)
Query: 45 KSRKGDVLHMHYT-----GKLEDGTEFDSSLPQNQPFVFSLGTGQVIK-GWDQGLLGMCE 98
++R GD + Y G EDG E+D P + + +G + +K +Q +G E
Sbjct: 404 RNRPGDKMRDRYNLNLLPGMSEDGVEYDDLEPNSLAVIPGMGIPEQLKLAMEQEQMGKDE 463
Query: 99 GEKRKLVIP 107
+ ++ IP
Sbjct: 464 SNEIEMTIP 472
>gi|51230412 GTPase activating Rap/RanGAP domain-like 1 isoform 2
[Homo sapiens]
Length = 2083
Score = 28.1 bits (61), Expect = 2.6
Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 5/71 (7%)
Query: 20 ATATGAEGKRKLQIGVKKR---VDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPF 76
AT TG+ G K + V+++ +D I R V H++ E G E +L + QP
Sbjct: 735 ATTTGSPGTEKARSIVRQKTVDIDDAQILPRSTRV--RHFSQSEETGNEVFGALNEEQPL 792
Query: 77 VFSLGTGQVIK 87
S T +++
Sbjct: 793 PRSSSTSDILE 803
>gi|51226124 GTPase activating Rap/RanGAP domain-like 1 isoform 1
[Homo sapiens]
Length = 2036
Score = 28.1 bits (61), Expect = 2.6
Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 5/71 (7%)
Query: 20 ATATGAEGKRKLQIGVKKR---VDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQNQPF 76
AT TG+ G K + V+++ +D I R V H++ E G E +L + QP
Sbjct: 735 ATTTGSPGTEKARSIVRQKTVDIDDAQILPRSTRV--RHFSQSEETGNEVFGALNEEQPL 792
Query: 77 VFSLGTGQVIK 87
S T +++
Sbjct: 793 PRSSSTSDILE 803
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.139 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,685,849
Number of Sequences: 37866
Number of extensions: 255093
Number of successful extensions: 503
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 450
Number of HSP's gapped (non-prelim): 53
length of query: 142
length of database: 18,247,518
effective HSP length: 92
effective length of query: 50
effective length of database: 14,763,846
effective search space: 738192300
effective search space used: 738192300
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.