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Search of human proteins with 206597470
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|206597470 neural precursor cell expressed, developmentally
down-regulated 1 isoform c [Homo sapiens]
(571 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|206597470 neural precursor cell expressed, developmentally do... 1128 0.0
gi|206597468 neural precursor cell expressed, developmentally do... 1128 0.0
gi|23097254 neural precursor cell expressed, developmentally dow... 1128 0.0
gi|206597465 neural precursor cell expressed, developmentally do... 1128 0.0
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 67 4e-11
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 61 3e-09
gi|48762926 PWP2 periodic tryptophan protein homolog [Homo sapiens] 60 4e-09
gi|16554629 WD repeat domain 5 [Homo sapiens] 60 5e-09
gi|16554627 WD repeat domain 5 [Homo sapiens] 60 5e-09
gi|23199987 WD repeat domain 5B [Homo sapiens] 60 7e-09
gi|55741849 WD repeat domain 22 [Homo sapiens] 58 2e-08
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 57 3e-08
gi|113865883 WD repeat domain 38 [Homo sapiens] 57 5e-08
gi|189571685 WD repeat, sterile alpha motif and U-box domain con... 54 5e-07
gi|189571683 WD repeat, sterile alpha motif and U-box domain con... 54 5e-07
gi|189571681 WD repeat, sterile alpha motif and U-box domain con... 54 5e-07
gi|5174447 guanine nucleotide binding protein (G protein), beta ... 53 7e-07
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 52 1e-06
gi|48928050 F-box and WD repeat domain containing 11 isoform C [... 52 1e-06
gi|13376840 WD repeat domain 61 [Homo sapiens] 52 1e-06
gi|48928048 F-box and WD repeat domain containing 11 isoform A [... 52 1e-06
gi|48928046 F-box and WD repeat domain containing 11 isoform B [... 52 1e-06
gi|5803221 WD repeat-containing protein 3 [Homo sapiens] 52 2e-06
gi|4502477 beta-transducin repeat containing protein isoform 2 [... 51 3e-06
gi|16117783 beta-transducin repeat containing protein isoform 1 ... 51 3e-06
gi|32483359 apoptotic peptidase activating factor 1 isoform c [H... 50 4e-06
gi|7108333 apoptotic peptidase activating factor 1 isoform a [Ho... 50 4e-06
gi|50980309 UTP15, U3 small nucleolar ribonucleoprotein, homolog... 50 7e-06
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 49 1e-05
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 49 1e-05
>gi|206597470 neural precursor cell expressed, developmentally
down-regulated 1 isoform c [Homo sapiens]
Length = 571
Score = 1128 bits (2918), Expect = 0.0
Identities = 571/571 (100%), Positives = 571/571 (100%)
Query: 1 MYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVT 60
MYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVT
Sbjct: 1 MYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVT 60
Query: 61 TNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 120
TNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA
Sbjct: 61 TNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 120
Query: 121 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR 180
SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR
Sbjct: 121 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR 180
Query: 181 GKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVN 240
GKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVN
Sbjct: 181 GKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVN 240
Query: 241 AASGGVQNSGIVREAPATSIATVLPQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDS 300
AASGGVQNSGIVREAPATSIATVLPQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDS
Sbjct: 241 AASGGVQNSGIVREAPATSIATVLPQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDS 300
Query: 301 GKNQDFSSFDDTGKSSLGDMFSPIRDDAVVNKGSDESIGKGDGFDFLPQLNSVFPPRKNP 360
GKNQDFSSFDDTGKSSLGDMFSPIRDDAVVNKGSDESIGKGDGFDFLPQLNSVFPPRKNP
Sbjct: 301 GKNQDFSSFDDTGKSSLGDMFSPIRDDAVVNKGSDESIGKGDGFDFLPQLNSVFPPRKNP 360
Query: 361 VTSSTSVLHSSPLNVFMGSPGKEENENRDLTAESKKIYMGKQESKDSFKQLAKLVTSGAE 420
VTSSTSVLHSSPLNVFMGSPGKEENENRDLTAESKKIYMGKQESKDSFKQLAKLVTSGAE
Sbjct: 361 VTSSTSVLHSSPLNVFMGSPGKEENENRDLTAESKKIYMGKQESKDSFKQLAKLVTSGAE 420
Query: 421 SGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPPINGSSTPNPKIASSVTAGVASSLSE 480
SGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPPINGSSTPNPKIASSVTAGVASSLSE
Sbjct: 421 SGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPPINGSSTPNPKIASSVTAGVASSLSE 480
Query: 481 KIADSIGNNRQNAPLTSIQIRFIQNMIQETLDDFREACHRDIVNLQVEMIKQFHMQLNEM 540
KIADSIGNNRQNAPLTSIQIRFIQNMIQETLDDFREACHRDIVNLQVEMIKQFHMQLNEM
Sbjct: 481 KIADSIGNNRQNAPLTSIQIRFIQNMIQETLDDFREACHRDIVNLQVEMIKQFHMQLNEM 540
Query: 541 HSLLERYSVNEGLVAEIERLREENKRLRAHF 571
HSLLERYSVNEGLVAEIERLREENKRLRAHF
Sbjct: 541 HSLLERYSVNEGLVAEIERLREENKRLRAHF 571
>gi|206597468 neural precursor cell expressed, developmentally
down-regulated 1 isoform b [Homo sapiens]
Length = 660
Score = 1128 bits (2918), Expect = 0.0
Identities = 571/571 (100%), Positives = 571/571 (100%)
Query: 1 MYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVT 60
MYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVT
Sbjct: 90 MYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVT 149
Query: 61 TNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 120
TNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA
Sbjct: 150 TNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 209
Query: 121 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR 180
SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR
Sbjct: 210 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR 269
Query: 181 GKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVN 240
GKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVN
Sbjct: 270 GKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVN 329
Query: 241 AASGGVQNSGIVREAPATSIATVLPQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDS 300
AASGGVQNSGIVREAPATSIATVLPQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDS
Sbjct: 330 AASGGVQNSGIVREAPATSIATVLPQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDS 389
Query: 301 GKNQDFSSFDDTGKSSLGDMFSPIRDDAVVNKGSDESIGKGDGFDFLPQLNSVFPPRKNP 360
GKNQDFSSFDDTGKSSLGDMFSPIRDDAVVNKGSDESIGKGDGFDFLPQLNSVFPPRKNP
Sbjct: 390 GKNQDFSSFDDTGKSSLGDMFSPIRDDAVVNKGSDESIGKGDGFDFLPQLNSVFPPRKNP 449
Query: 361 VTSSTSVLHSSPLNVFMGSPGKEENENRDLTAESKKIYMGKQESKDSFKQLAKLVTSGAE 420
VTSSTSVLHSSPLNVFMGSPGKEENENRDLTAESKKIYMGKQESKDSFKQLAKLVTSGAE
Sbjct: 450 VTSSTSVLHSSPLNVFMGSPGKEENENRDLTAESKKIYMGKQESKDSFKQLAKLVTSGAE 509
Query: 421 SGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPPINGSSTPNPKIASSVTAGVASSLSE 480
SGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPPINGSSTPNPKIASSVTAGVASSLSE
Sbjct: 510 SGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPPINGSSTPNPKIASSVTAGVASSLSE 569
Query: 481 KIADSIGNNRQNAPLTSIQIRFIQNMIQETLDDFREACHRDIVNLQVEMIKQFHMQLNEM 540
KIADSIGNNRQNAPLTSIQIRFIQNMIQETLDDFREACHRDIVNLQVEMIKQFHMQLNEM
Sbjct: 570 KIADSIGNNRQNAPLTSIQIRFIQNMIQETLDDFREACHRDIVNLQVEMIKQFHMQLNEM 629
Query: 541 HSLLERYSVNEGLVAEIERLREENKRLRAHF 571
HSLLERYSVNEGLVAEIERLREENKRLRAHF
Sbjct: 630 HSLLERYSVNEGLVAEIERLREENKRLRAHF 660
>gi|23097254 neural precursor cell expressed, developmentally
down-regulated 1 isoform b [Homo sapiens]
Length = 660
Score = 1128 bits (2918), Expect = 0.0
Identities = 571/571 (100%), Positives = 571/571 (100%)
Query: 1 MYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVT 60
MYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVT
Sbjct: 90 MYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVT 149
Query: 61 TNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 120
TNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA
Sbjct: 150 TNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 209
Query: 121 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR 180
SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR
Sbjct: 210 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR 269
Query: 181 GKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVN 240
GKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVN
Sbjct: 270 GKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVN 329
Query: 241 AASGGVQNSGIVREAPATSIATVLPQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDS 300
AASGGVQNSGIVREAPATSIATVLPQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDS
Sbjct: 330 AASGGVQNSGIVREAPATSIATVLPQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDS 389
Query: 301 GKNQDFSSFDDTGKSSLGDMFSPIRDDAVVNKGSDESIGKGDGFDFLPQLNSVFPPRKNP 360
GKNQDFSSFDDTGKSSLGDMFSPIRDDAVVNKGSDESIGKGDGFDFLPQLNSVFPPRKNP
Sbjct: 390 GKNQDFSSFDDTGKSSLGDMFSPIRDDAVVNKGSDESIGKGDGFDFLPQLNSVFPPRKNP 449
Query: 361 VTSSTSVLHSSPLNVFMGSPGKEENENRDLTAESKKIYMGKQESKDSFKQLAKLVTSGAE 420
VTSSTSVLHSSPLNVFMGSPGKEENENRDLTAESKKIYMGKQESKDSFKQLAKLVTSGAE
Sbjct: 450 VTSSTSVLHSSPLNVFMGSPGKEENENRDLTAESKKIYMGKQESKDSFKQLAKLVTSGAE 509
Query: 421 SGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPPINGSSTPNPKIASSVTAGVASSLSE 480
SGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPPINGSSTPNPKIASSVTAGVASSLSE
Sbjct: 510 SGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPPINGSSTPNPKIASSVTAGVASSLSE 569
Query: 481 KIADSIGNNRQNAPLTSIQIRFIQNMIQETLDDFREACHRDIVNLQVEMIKQFHMQLNEM 540
KIADSIGNNRQNAPLTSIQIRFIQNMIQETLDDFREACHRDIVNLQVEMIKQFHMQLNEM
Sbjct: 570 KIADSIGNNRQNAPLTSIQIRFIQNMIQETLDDFREACHRDIVNLQVEMIKQFHMQLNEM 629
Query: 541 HSLLERYSVNEGLVAEIERLREENKRLRAHF 571
HSLLERYSVNEGLVAEIERLREENKRLRAHF
Sbjct: 630 HSLLERYSVNEGLVAEIERLREENKRLRAHF 660
>gi|206597465 neural precursor cell expressed, developmentally
down-regulated 1 isoform a [Homo sapiens]
Length = 667
Score = 1128 bits (2918), Expect = 0.0
Identities = 571/571 (100%), Positives = 571/571 (100%)
Query: 1 MYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVT 60
MYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVT
Sbjct: 97 MYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVT 156
Query: 61 TNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 120
TNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA
Sbjct: 157 TNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 216
Query: 121 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR 180
SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR
Sbjct: 217 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR 276
Query: 181 GKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVN 240
GKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVN
Sbjct: 277 GKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKGCSNKPTTVNKRSVNVN 336
Query: 241 AASGGVQNSGIVREAPATSIATVLPQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDS 300
AASGGVQNSGIVREAPATSIATVLPQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDS
Sbjct: 337 AASGGVQNSGIVREAPATSIATVLPQPMTSAMGKGTVAVQEKAGLPRSINTDTLSKETDS 396
Query: 301 GKNQDFSSFDDTGKSSLGDMFSPIRDDAVVNKGSDESIGKGDGFDFLPQLNSVFPPRKNP 360
GKNQDFSSFDDTGKSSLGDMFSPIRDDAVVNKGSDESIGKGDGFDFLPQLNSVFPPRKNP
Sbjct: 397 GKNQDFSSFDDTGKSSLGDMFSPIRDDAVVNKGSDESIGKGDGFDFLPQLNSVFPPRKNP 456
Query: 361 VTSSTSVLHSSPLNVFMGSPGKEENENRDLTAESKKIYMGKQESKDSFKQLAKLVTSGAE 420
VTSSTSVLHSSPLNVFMGSPGKEENENRDLTAESKKIYMGKQESKDSFKQLAKLVTSGAE
Sbjct: 457 VTSSTSVLHSSPLNVFMGSPGKEENENRDLTAESKKIYMGKQESKDSFKQLAKLVTSGAE 516
Query: 421 SGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPPINGSSTPNPKIASSVTAGVASSLSE 480
SGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPPINGSSTPNPKIASSVTAGVASSLSE
Sbjct: 517 SGNLNTSPSSNQTRNSEKFEKPENEIEAQLICEPPINGSSTPNPKIASSVTAGVASSLSE 576
Query: 481 KIADSIGNNRQNAPLTSIQIRFIQNMIQETLDDFREACHRDIVNLQVEMIKQFHMQLNEM 540
KIADSIGNNRQNAPLTSIQIRFIQNMIQETLDDFREACHRDIVNLQVEMIKQFHMQLNEM
Sbjct: 577 KIADSIGNNRQNAPLTSIQIRFIQNMIQETLDDFREACHRDIVNLQVEMIKQFHMQLNEM 636
Query: 541 HSLLERYSVNEGLVAEIERLREENKRLRAHF 571
HSLLERYSVNEGLVAEIERLREENKRLRAHF
Sbjct: 637 HSLLERYSVNEGLVAEIERLREENKRLRAHF 667
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 67.0 bits (162), Expect = 4e-11
Identities = 49/176 (27%), Positives = 87/176 (49%), Gaps = 5/176 (2%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTN 62
+V+G + ++ +WDL++ ++ R+L HK + + ++ ++ASGS I L +
Sbjct: 78 IVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRK 137
Query: 63 LSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASG 122
+ G +Q+VR L++S K L S +D+ V LWD+ + F H P +
Sbjct: 138 GCVFRY-RGHSQAVRCLRFSPDGK-WLASAADDHTVKLWDLTAGKMMSEFPG-HTGPVNV 194
Query: 123 ICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADT-PLTAVDFMPDGATLAIG 177
+ F P NE L + D+ I +D ++V + + P+ +V F PDG L G
Sbjct: 195 VEFHP-NEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSG 249
Score = 54.3 bits (129), Expect = 3e-07
Identities = 58/211 (27%), Positives = 89/211 (42%), Gaps = 10/211 (4%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSV-TT 61
L +GG + VN+W + SL H V V N + I +GS SG I + +
Sbjct: 36 LATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAA 95
Query: 62 NLSSTPFGHGSN-QSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 120
+ T GH +N S+ Y F S GS N + LWD+ + + H
Sbjct: 96 KILRTLMGHKANICSLDFHPYGEFVAS--GSQDTN--IKLWDIRRKGCVFRYRG-HSQAV 150
Query: 121 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADT-PLTAVDFMPDGATLAIGSS 179
+ FSP + L + D + L+D ++ K++ T P+ V+F P+ LA GSS
Sbjct: 151 RCLRFSPDGKWL-ASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSS 209
Query: 180 RGKIYQYDLRMLKSPVKTISAHKTSVQCIAF 210
I +DL + V I V+ + F
Sbjct: 210 DRTIRFWDLEKFQ-VVSCIEGEPGPVRSVLF 239
Score = 32.3 bits (72), Expect = 1.2
Identities = 15/48 (31%), Positives = 26/48 (54%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGS 49
+L S ++TV +WDL + ++ H V V ++ N+ +ASGS
Sbjct: 161 WLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGS 208
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 60.8 bits (146), Expect = 3e-09
Identities = 75/306 (24%), Positives = 129/306 (42%), Gaps = 31/306 (10%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTN 62
L SG +++ + +W +K + HKD VTCV ++ + +ASGS + +
Sbjct: 34 LASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVK 93
Query: 63 LSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASG 122
ST F +VR + + +S + + SD+ V +W + Q + S H
Sbjct: 94 GESTVF-RAHTATVRSVHFCSDGQSFV-TASDDKTVKVWATHRQKFLFSL-SQHINWVRC 150
Query: 123 ICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTP-LTAVDFMPDGATLAIGSSRG 181
FSP L+ V+ DK + L+D SS++ V + +T VDF P G +A
Sbjct: 151 AKFSPDGRLI-VSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDN 209
Query: 182 KIYQYDLRMLKSPVKTISAHKTSVQCIAFQYS-----TVLTKSSLN-------------K 223
+ +D+R + ++ H +V ++F S T + S+L
Sbjct: 210 TVKVWDVRTHRL-LQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLH 268
Query: 224 GCSNKPTTVNKRSVNVNAASGGVQNSGIVREAPATSI----ATVLPQP---MTSAMGKGT 276
G TTV ASGG +V ++ + T +P+P + S+MG T
Sbjct: 269 GHQGPATTVAFSRTGEYFASGGSDEQVMVWKSNFDIVDHGEVTKVPRPPATLASSMGNLT 328
Query: 277 VAVQEK 282
V++ E+
Sbjct: 329 VSILEQ 334
>gi|48762926 PWP2 periodic tryptophan protein homolog [Homo sapiens]
Length = 919
Score = 60.5 bits (145), Expect = 4e-09
Identities = 48/192 (25%), Positives = 86/192 (44%), Gaps = 13/192 (6%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTT 61
Y+V+GG + V +W+ S + +H VT VT+ + + S+ G + +
Sbjct: 387 YIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHR 446
Query: 62 NLSSTPFGHGSNQSVRHLKYSLFKKSLLGSV-----SDNGIVTLWDVNSQSPYHNFDSVH 116
+ F S R ++S G + D+ + +W + + + S H
Sbjct: 447 YRNFRTF-----TSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQT-GRLLDVLSGH 500
Query: 117 KAPASGICFSPVNELLFVTIGLDKRIILYDT-SSKKLVKTLVADTPLTAVDFMPDGATLA 175
+ P SG+CF+P+ +L + DK + L+D S + +TL + AV F PDGA LA
Sbjct: 501 EGPISGLCFNPMKSVL-ASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRPDGAELA 559
Query: 176 IGSSRGKIYQYD 187
+ + +I +D
Sbjct: 560 VATLNSQITFWD 571
Score = 30.0 bits (66), Expect = 6.0
Identities = 32/143 (22%), Positives = 58/143 (40%), Gaps = 3/143 (2%)
Query: 72 SNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNEL 131
S+QS+ + + + S G + +W+ S+S Y H + +SP +
Sbjct: 329 SDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSES-YVLKQQGHFNSMVALAYSPDGQY 387
Query: 132 LFVTIGLDKRIILYDTSSKKLVKTLVADTP-LTAVDFMPDGATLAIGSSRGKIYQYDLRM 190
+ VT G D ++ +++T S T + +T V F G + S G + +DL
Sbjct: 388 I-VTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHR 446
Query: 191 LKSPVKTISAHKTSVQCIAFQYS 213
++ S T C+A S
Sbjct: 447 YRNFRTFTSPRPTQFSCVAVDAS 469
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 60.1 bits (144), Expect = 5e-09
Identities = 56/205 (27%), Positives = 85/205 (41%), Gaps = 12/205 (5%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTN 62
LVS + T+ IWD+ S + ++LK H + V C +N I SGS + + V T
Sbjct: 102 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTG 161
Query: 63 --LSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 120
L + P H S H SL+ S S +G+ +WD S P
Sbjct: 162 KCLKTLP-AHSDPVSAVHFNRD---GSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPV 217
Query: 121 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTP----LTAVDFMPDGATLAI 176
S + FSP N + LD + L+D S K +KT + A + G +
Sbjct: 218 SFVKFSP-NGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVS 276
Query: 177 GSSRGKIYQYDLRMLKSPVKTISAH 201
GS +Y ++L+ K V+ + H
Sbjct: 277 GSEDNLVYIWNLQ-TKEIVQKLQGH 300
Score = 49.7 bits (117), Expect = 7e-06
Identities = 48/215 (22%), Positives = 94/215 (43%), Gaps = 9/215 (4%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTT 61
+L S + + IW + +++ HK ++ V ++ + + S S + + V++
Sbjct: 59 WLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSS 118
Query: 62 -NLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 120
T GH + + + +L+ S S + V +WDV + + H P
Sbjct: 119 GKCLKTLKGHSNYVFCCNFNP---QSNLIVSGSFDESVRIWDVKTGKCLKTLPA-HSDPV 174
Query: 121 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVAD--TPLTAVDFMPDGATLAIGS 178
S + F+ L+ V+ D ++DT+S + +KTL+ D P++ V F P+G + +
Sbjct: 175 SAVHFNRDGSLI-VSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAAT 233
Query: 179 SRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYS 213
+ +D K +KT + HK CI +S
Sbjct: 234 LDNTLKLWDYSKGKC-LKTYTGHKNEKYCIFANFS 267
Score = 40.8 bits (94), Expect = 0.003
Identities = 43/159 (27%), Positives = 73/159 (45%), Gaps = 7/159 (4%)
Query: 25 SLKDHKDQVTCVTYNWNDCYIASGSLSGEI-ILHSVTTNLSSTPFGHGSNQSVRHLKYSL 83
+L H V+ V ++ N ++AS S I I + T GH + + +S
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH--KLGISDVAWSS 97
Query: 84 FKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRII 143
+LL S SD+ + +WDV+S H F+P + L+ V+ D+ +
Sbjct: 98 -DSNLLVSASDDKTLKIWDVSSGKCLKTLKG-HSNYVFCCNFNPQSNLI-VSGSFDESVR 154
Query: 144 LYDTSSKKLVKTLVADT-PLTAVDFMPDGATLAIGSSRG 181
++D + K +KTL A + P++AV F DG+ + S G
Sbjct: 155 IWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDG 193
Score = 35.4 bits (80), Expect = 0.14
Identities = 17/52 (32%), Positives = 30/52 (57%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGE 53
++VSG +N V IW+L++K + + L+ H D V + + IAS +L +
Sbjct: 273 WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALEND 324
Score = 34.3 bits (77), Expect = 0.32
Identities = 35/187 (18%), Positives = 61/187 (32%), Gaps = 44/187 (23%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTN 62
+VSG + +V IWD+K+ + ++L H D V+ V +N + I S S G + +
Sbjct: 144 IVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASG 203
Query: 63 LSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDN--------------------------- 95
N V +K+S K +L + DN
Sbjct: 204 QCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIF 263
Query: 96 -----------------GIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGL 138
+V +W++ ++ S C N + +
Sbjct: 264 ANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALEN 323
Query: 139 DKRIILY 145
DK I L+
Sbjct: 324 DKTIKLW 330
Score = 32.3 bits (72), Expect = 1.2
Identities = 15/63 (23%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWN---DCYIASGSLSGEIILHS 58
Y+++ L+NT+ +WD + ++ HK++ C+ N++ +I SGS + + +
Sbjct: 228 YILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWN 287
Query: 59 VTT 61
+ T
Sbjct: 288 LQT 290
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 60.1 bits (144), Expect = 5e-09
Identities = 56/205 (27%), Positives = 85/205 (41%), Gaps = 12/205 (5%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTN 62
LVS + T+ IWD+ S + ++LK H + V C +N I SGS + + V T
Sbjct: 102 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTG 161
Query: 63 --LSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 120
L + P H S H SL+ S S +G+ +WD S P
Sbjct: 162 KCLKTLP-AHSDPVSAVHFNRD---GSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPV 217
Query: 121 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTP----LTAVDFMPDGATLAI 176
S + FSP N + LD + L+D S K +KT + A + G +
Sbjct: 218 SFVKFSP-NGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVS 276
Query: 177 GSSRGKIYQYDLRMLKSPVKTISAH 201
GS +Y ++L+ K V+ + H
Sbjct: 277 GSEDNLVYIWNLQ-TKEIVQKLQGH 300
Score = 49.7 bits (117), Expect = 7e-06
Identities = 48/215 (22%), Positives = 94/215 (43%), Gaps = 9/215 (4%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTT 61
+L S + + IW + +++ HK ++ V ++ + + S S + + V++
Sbjct: 59 WLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSS 118
Query: 62 -NLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 120
T GH + + + +L+ S S + V +WDV + + H P
Sbjct: 119 GKCLKTLKGHSNYVFCCNFNP---QSNLIVSGSFDESVRIWDVKTGKCLKTLPA-HSDPV 174
Query: 121 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVAD--TPLTAVDFMPDGATLAIGS 178
S + F+ L+ V+ D ++DT+S + +KTL+ D P++ V F P+G + +
Sbjct: 175 SAVHFNRDGSLI-VSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAAT 233
Query: 179 SRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYS 213
+ +D K +KT + HK CI +S
Sbjct: 234 LDNTLKLWDYSKGKC-LKTYTGHKNEKYCIFANFS 267
Score = 40.8 bits (94), Expect = 0.003
Identities = 43/159 (27%), Positives = 73/159 (45%), Gaps = 7/159 (4%)
Query: 25 SLKDHKDQVTCVTYNWNDCYIASGSLSGEI-ILHSVTTNLSSTPFGHGSNQSVRHLKYSL 83
+L H V+ V ++ N ++AS S I I + T GH + + +S
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH--KLGISDVAWSS 97
Query: 84 FKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRII 143
+LL S SD+ + +WDV+S H F+P + L+ V+ D+ +
Sbjct: 98 -DSNLLVSASDDKTLKIWDVSSGKCLKTLKG-HSNYVFCCNFNPQSNLI-VSGSFDESVR 154
Query: 144 LYDTSSKKLVKTLVADT-PLTAVDFMPDGATLAIGSSRG 181
++D + K +KTL A + P++AV F DG+ + S G
Sbjct: 155 IWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDG 193
Score = 35.4 bits (80), Expect = 0.14
Identities = 17/52 (32%), Positives = 30/52 (57%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGE 53
++VSG +N V IW+L++K + + L+ H D V + + IAS +L +
Sbjct: 273 WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALEND 324
Score = 34.3 bits (77), Expect = 0.32
Identities = 35/187 (18%), Positives = 61/187 (32%), Gaps = 44/187 (23%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTN 62
+VSG + +V IWD+K+ + ++L H D V+ V +N + I S S G + +
Sbjct: 144 IVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASG 203
Query: 63 LSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDN--------------------------- 95
N V +K+S K +L + DN
Sbjct: 204 QCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIF 263
Query: 96 -----------------GIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGL 138
+V +W++ ++ S C N + +
Sbjct: 264 ANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALEN 323
Query: 139 DKRIILY 145
DK I L+
Sbjct: 324 DKTIKLW 330
Score = 32.3 bits (72), Expect = 1.2
Identities = 15/63 (23%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWN---DCYIASGSLSGEIILHS 58
Y+++ L+NT+ +WD + ++ HK++ C+ N++ +I SGS + + +
Sbjct: 228 YILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWN 287
Query: 59 VTT 61
+ T
Sbjct: 288 LQT 290
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 59.7 bits (143), Expect = 7e-09
Identities = 55/204 (26%), Positives = 86/204 (42%), Gaps = 10/204 (4%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTT- 61
LVS + T+ +WD++S + ++LK H + V C +N I SGS + + V T
Sbjct: 98 LVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTG 157
Query: 62 NLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPAS 121
T H S H S SL+ S S +G+ +WD S P S
Sbjct: 158 KCLKTLSAHSDPVSAVHFNCS---GSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVS 214
Query: 122 GICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTP----LTAVDFMPDGATLAIG 177
+ FSP N +T LD + L+D S + +KT + A + G + G
Sbjct: 215 FVKFSP-NGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSG 273
Query: 178 SSRGKIYQYDLRMLKSPVKTISAH 201
S +Y ++L+ K V+ + H
Sbjct: 274 SEDNLVYIWNLQ-TKEIVQKLQGH 296
Score = 50.8 bits (120), Expect = 3e-06
Identities = 40/160 (25%), Positives = 70/160 (43%), Gaps = 4/160 (2%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTN 62
++SG + TV IW++K+ + ++L H D V+ V +N + I SGS G + +
Sbjct: 140 IISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASG 199
Query: 63 LSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASG 122
N V +K+S K +L + DN + LWD + + HK
Sbjct: 200 QCLKTLVDDDNPPVSFVKFSPNGKYILTATLDN-TLKLWDYSRGRCLKTYTG-HKNEKYC 257
Query: 123 IC--FSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADT 160
I FS V+ D + +++ +K++V+ L T
Sbjct: 258 IFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHT 297
Score = 44.3 bits (103), Expect = 3e-04
Identities = 45/180 (25%), Positives = 82/180 (45%), Gaps = 7/180 (3%)
Query: 4 VSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTN- 62
+S N + + + + + +L H + V+ V ++ N ++AS S II+
Sbjct: 15 LSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGK 74
Query: 63 LSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASG 122
T +GH N + + +S S L S SD+ + LWDV S H
Sbjct: 75 YEKTLYGH--NLEISDVAWSS-DSSRLVSASDDKTLKLWDVRSGKCLKTLKG-HSNYVFC 130
Query: 123 ICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADT-PLTAVDFMPDGATLAIGSSRG 181
F+P + L+ ++ D+ + +++ + K +KTL A + P++AV F G+ + GS G
Sbjct: 131 CNFNPPSNLI-ISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDG 189
Score = 35.4 bits (80), Expect = 0.14
Identities = 39/155 (25%), Positives = 66/155 (42%), Gaps = 5/155 (3%)
Query: 71 GSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNE 130
G ++V +K+S + L S +D ++ +W Y H S + +S +
Sbjct: 39 GHTEAVSSVKFSPNGEWLASSSADR-LIIIWGAYD-GKYEKTLYGHNLEISDVAWSSDSS 96
Query: 131 LLFVTIGLDKRIILYDTSSKKLVKTLVADTPLT-AVDFMPDGATLAIGSSRGKIYQYDLR 189
L V+ DK + L+D S K +KTL + +F P + GS + ++++
Sbjct: 97 RL-VSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVK 155
Query: 190 MLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKG 224
K +KT+SAH V + F S L S G
Sbjct: 156 TGKC-LKTLSAHSDPVSAVHFNCSGSLIVSGSYDG 189
Score = 35.4 bits (80), Expect = 0.14
Identities = 17/52 (32%), Positives = 30/52 (57%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGE 53
++VSG +N V IW+L++K + + L+ H D V + + IAS +L +
Sbjct: 269 WIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALEND 320
Score = 33.1 bits (74), Expect = 0.71
Identities = 16/63 (25%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWN---DCYIASGSLSGEIILHS 58
Y+++ L+NT+ +WD R ++ HK++ C+ N++ +I SGS + + +
Sbjct: 224 YILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWN 283
Query: 59 VTT 61
+ T
Sbjct: 284 LQT 286
>gi|55741849 WD repeat domain 22 [Homo sapiens]
Length = 942
Score = 58.2 bits (139), Expect = 2e-08
Identities = 40/153 (26%), Positives = 75/153 (49%), Gaps = 12/153 (7%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLK------DHKDQVTCVTYNWNDCYIASGSLSGEII 55
+LVSGG + V +W ++ + +H +K +H + C+ +N + + SG ++I
Sbjct: 68 WLVSGGDDRRVLLWHME-QAIHSRVKPIQLKGEHHSNIFCLAFNSGNTKVFSGGNDEQVI 126
Query: 56 LHSVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSV 115
LH V ++ + F H +V L S ++ S SD+G V +WD+ +SP+ +
Sbjct: 127 LHDVESSETLDVFAH--EDAVYGLSVSPVNDNIFASSSDDGRVLIWDIR-ESPHGEPFCL 183
Query: 116 HKAPAS--GICFSPVNELLFVTIGLDKRIILYD 146
P++ + F+PV L T + + L+D
Sbjct: 184 ANYPSAFHSVMFNPVEPRLLATANSKEGVGLWD 216
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 57.4 bits (137), Expect = 3e-08
Identities = 54/212 (25%), Positives = 95/212 (44%), Gaps = 6/212 (2%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTN 62
L SG +++ + +W +K + HKD VTCV ++ + +ASGS + +
Sbjct: 34 LASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVK 93
Query: 63 LSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASG 122
ST F +VR + + +S + + SD+ V +W + Q + S H
Sbjct: 94 GESTVF-RAHTATVRSVHFCSDGQSFV-TASDDKTVKVWATHRQKFLFSL-SQHINWVRC 150
Query: 123 ICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTP-LTAVDFMPDGATLAIGSSRG 181
FSP L+ V+ DK + L+D SS++ V + +T VDF P G +A
Sbjct: 151 AKFSPDGRLI-VSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDN 209
Query: 182 KIYQYDLRMLKSPVKTISAHKTSVQCIAFQYS 213
+ +D+R + ++ H +V ++F S
Sbjct: 210 TVKVWDVRTHRL-LQHYQLHSAAVNGLSFHPS 240
Score = 41.6 bits (96), Expect = 0.002
Identities = 42/167 (25%), Positives = 71/167 (42%), Gaps = 5/167 (2%)
Query: 22 VHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVRHLKY 81
+ R K H+D VTCV ++ N +ASGS+ +++ + + F G +V + +
Sbjct: 11 LERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRF-TGHKDAVTCVNF 69
Query: 82 SLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKR 141
S LL S S + V +W N + F H A + F + FVT DK
Sbjct: 70 SP-SGHLLASGSRDKTVRIWVPNVKGESTVF-RAHTATVRSVHFCSDGQ-SFVTASDDKT 126
Query: 142 IILYDTSSKKLVKTLVADTP-LTAVDFMPDGATLAIGSSRGKIYQYD 187
+ ++ T +K + +L + F PDG + S + +D
Sbjct: 127 VKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD 173
Score = 32.3 bits (72), Expect = 1.2
Identities = 17/69 (24%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEI-ILHSVTT 61
+ + G++NTV +WD+++ R+ + + H V ++++ + Y+ + S + IL +
Sbjct: 202 IAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEG 261
Query: 62 NLSSTPFGH 70
L T GH
Sbjct: 262 RLLYTLHGH 270
>gi|113865883 WD repeat domain 38 [Homo sapiens]
Length = 314
Score = 57.0 bits (136), Expect = 5e-08
Identities = 44/148 (29%), Positives = 73/148 (49%), Gaps = 6/148 (4%)
Query: 88 LLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDT 147
L S S + V LWDV +++ H+ + FSP + L + G DKR++L+D
Sbjct: 77 LFASASCDCTVRLWDV-ARAKCLRVLKGHQRSVETVSFSPDSRQL-ASGGWDKRVMLWDV 134
Query: 148 SSKKLVKTLVADTP-LTAVDFMPDGATLAIGSSRGKIYQYDLRMLKSPV--KTISAHKTS 204
S ++++ LV + + DF P LA GS ++ +DLRM+ V + + H +
Sbjct: 135 QSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSAN 194
Query: 205 VQCIAFQYSTVLTKSSLNKGCSN-KPTT 231
+ C+ + S +L S +K KPTT
Sbjct: 195 ISCLCYSASGLLASGSWDKTIHIWKPTT 222
Score = 52.8 bits (125), Expect = 9e-07
Identities = 53/183 (28%), Positives = 84/183 (45%), Gaps = 13/183 (7%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEI---ILHSV 59
L SGG + V +WD++S ++ R L H+D + ++ +A+GS + L V
Sbjct: 120 LASGGWDKRVMLWDVQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMV 179
Query: 60 TTNLSSTPF-GHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKA 118
T +S GH +N S L YS LL S S + + +W + S H
Sbjct: 180 TPAVSHQALEGHSANISC--LCYS--ASGLLASGSWDKTIHIWKPTTSSLLIQLKG-HVT 234
Query: 119 PASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTL--VADTPLTAVDFMPDGATLAI 176
I FSP +EL + G + + ++D ++ K ++TL V D T F PDG L
Sbjct: 235 WVKSIAFSP-DELWLASAGYSRMVKVWDCNTGKCLETLKGVLDVAHTCA-FTPDGKILVS 292
Query: 177 GSS 179
G++
Sbjct: 293 GAA 295
Score = 43.1 bits (100), Expect = 7e-04
Identities = 45/175 (25%), Positives = 79/175 (45%), Gaps = 9/175 (5%)
Query: 5 SGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTT-NL 63
S + TV +WD+ + R LK H+ V V+++ + +ASG ++L V + +
Sbjct: 80 SASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQM 139
Query: 64 SSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSP--YHNFDSVHKAPAS 121
GH S++ +S + L + S + V +WD+ +P H H A S
Sbjct: 140 LRLLVGH--RDSIQSSDFSP-TVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANIS 196
Query: 122 GICFSPVNELLFVTIGLDKRIILY-DTSSKKLVKTLVADTPLTAVDFMPDGATLA 175
+C+S L + DK I ++ T+S L++ T + ++ F PD LA
Sbjct: 197 CLCYSASG--LLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLA 249
>gi|189571685 WD repeat, sterile alpha motif and U-box domain
containing 1 [Homo sapiens]
Length = 476
Score = 53.5 bits (127), Expect = 5e-07
Identities = 55/214 (25%), Positives = 93/214 (43%), Gaps = 35/214 (16%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEI-------- 54
L SG + TV +W+ +S +++R + ++ N + +GS G++
Sbjct: 112 LASGAADGTVVLWNAQSYKLYRCGSVKDGSLAACAFSPNGSFFVTGSSCGDLTVWDDKMR 171
Query: 55 ILHS--------VTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVN-- 104
LHS + SS P G Q ++ + L S + V +W V+
Sbjct: 172 CLHSEKAHDLGITCCDFSSQPVSDG-EQGLQFFR--------LASCGQDCQVKIWIVSFT 222
Query: 105 ----SQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADT 160
+ Y + S H AP FS ++L V+ +DK +I+YDT+++ ++ TL T
Sbjct: 223 HILGFELKYKSTLSGHCAPVLACAFSHDGQML-VSGSVDKSVIVYDTNTENILHTLTQHT 281
Query: 161 P-LTAVDFMPDGATLAIGS--SRGKIYQYDLRML 191
+T F P+ LA GS I+Q+DL L
Sbjct: 282 RYVTTCAFAPNTLLLATGSMDKTVNIWQFDLETL 315
>gi|189571683 WD repeat, sterile alpha motif and U-box domain
containing 1 [Homo sapiens]
Length = 476
Score = 53.5 bits (127), Expect = 5e-07
Identities = 55/214 (25%), Positives = 93/214 (43%), Gaps = 35/214 (16%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEI-------- 54
L SG + TV +W+ +S +++R + ++ N + +GS G++
Sbjct: 112 LASGAADGTVVLWNAQSYKLYRCGSVKDGSLAACAFSPNGSFFVTGSSCGDLTVWDDKMR 171
Query: 55 ILHS--------VTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVN-- 104
LHS + SS P G Q ++ + L S + V +W V+
Sbjct: 172 CLHSEKAHDLGITCCDFSSQPVSDG-EQGLQFFR--------LASCGQDCQVKIWIVSFT 222
Query: 105 ----SQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADT 160
+ Y + S H AP FS ++L V+ +DK +I+YDT+++ ++ TL T
Sbjct: 223 HILGFELKYKSTLSGHCAPVLACAFSHDGQML-VSGSVDKSVIVYDTNTENILHTLTQHT 281
Query: 161 P-LTAVDFMPDGATLAIGS--SRGKIYQYDLRML 191
+T F P+ LA GS I+Q+DL L
Sbjct: 282 RYVTTCAFAPNTLLLATGSMDKTVNIWQFDLETL 315
>gi|189571681 WD repeat, sterile alpha motif and U-box domain
containing 1 [Homo sapiens]
Length = 476
Score = 53.5 bits (127), Expect = 5e-07
Identities = 55/214 (25%), Positives = 93/214 (43%), Gaps = 35/214 (16%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEI-------- 54
L SG + TV +W+ +S +++R + ++ N + +GS G++
Sbjct: 112 LASGAADGTVVLWNAQSYKLYRCGSVKDGSLAACAFSPNGSFFVTGSSCGDLTVWDDKMR 171
Query: 55 ILHS--------VTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVN-- 104
LHS + SS P G Q ++ + L S + V +W V+
Sbjct: 172 CLHSEKAHDLGITCCDFSSQPVSDG-EQGLQFFR--------LASCGQDCQVKIWIVSFT 222
Query: 105 ----SQSPYHNFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADT 160
+ Y + S H AP FS ++L V+ +DK +I+YDT+++ ++ TL T
Sbjct: 223 HILGFELKYKSTLSGHCAPVLACAFSHDGQML-VSGSVDKSVIVYDTNTENILHTLTQHT 281
Query: 161 P-LTAVDFMPDGATLAIGS--SRGKIYQYDLRML 191
+T F P+ LA GS I+Q+DL L
Sbjct: 282 RYVTTCAFAPNTLLLATGSMDKTVNIWQFDLETL 315
>gi|5174447 guanine nucleotide binding protein (G protein), beta
polypeptide 2-like 1 [Homo sapiens]
Length = 317
Score = 53.1 bits (126), Expect = 7e-07
Identities = 47/193 (24%), Positives = 85/193 (44%), Gaps = 9/193 (4%)
Query: 3 LVSGGLNNTVNIWDLKSKRVH-----RSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILH 57
++S + T+ +W L + R+L+ H V+ V + + + SGS G + L
Sbjct: 31 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
Query: 58 SVTTNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHK 117
+TT ++ F G + V + +S + ++ D + LW+ Y D H
Sbjct: 91 DLTTGTTTRRF-VGHTKDVLSVAFSSDNRQIVSGSRDK-TIKLWNTLGVCKYTVQDESHS 148
Query: 118 APASGICFSP-VNELLFVTIGLDKRIILYDTSSKKLVKTLVADTP-LTAVDFMPDGATLA 175
S + FSP + + V+ G DK + +++ ++ KL + T L V PDG+ A
Sbjct: 149 EWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCA 208
Query: 176 IGSSRGKIYQYDL 188
G G+ +DL
Sbjct: 209 SGGKDGQAMLWDL 221
Score = 40.4 bits (93), Expect = 0.004
Identities = 49/221 (22%), Positives = 92/221 (41%), Gaps = 14/221 (6%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTT 61
+ +SG + T+ +WDL + R H V V ++ ++ I SGS I L +
Sbjct: 77 FALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLG 136
Query: 62 NLSSTPFGHGSNQSVRHLKYSLFKKS-LLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 120
T ++ V +++S + ++ S + +V +W++ + N H
Sbjct: 137 VCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIG-HTGYL 195
Query: 121 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPD--------GA 172
+ + SP L + G D + +L+D + K + TL + A+ F P+ G
Sbjct: 196 NTVTVSPDGSLC-ASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGP 254
Query: 173 TLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYS 213
++ I GKI + LK V + S+ QC + +S
Sbjct: 255 SIKIWDLEGKII---VDELKQEVISTSSKAEPPQCTSLAWS 292
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 52.0 bits (123), Expect = 1e-06
Identities = 51/207 (24%), Positives = 92/207 (44%), Gaps = 6/207 (2%)
Query: 8 LNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTP 67
+++ + +W +K + HKD VTCV ++ + +ASGS + + ST
Sbjct: 1 MDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTV 60
Query: 68 FGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSP 127
F +VR + + +S + + SD+ V +W + Q + S H FSP
Sbjct: 61 F-RAHTATVRSVHFCSDGQSFV-TASDDKTVKVWATHRQKFLFSL-SQHINWVRCAKFSP 117
Query: 128 VNELLFVTIGLDKRIILYDTSSKKLVKTLVADTP-LTAVDFMPDGATLAIGSSRGKIYQY 186
L+ V+ DK + L+D SS++ V + +T VDF P G +A + +
Sbjct: 118 DGRLI-VSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVW 176
Query: 187 DLRMLKSPVKTISAHKTSVQCIAFQYS 213
D+R + ++ H +V ++F S
Sbjct: 177 DVRTHRL-LQHYQLHSAAVNGLSFHPS 202
Score = 40.4 bits (93), Expect = 0.004
Identities = 43/179 (24%), Positives = 71/179 (39%), Gaps = 9/179 (5%)
Query: 4 VSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTNL 63
V+ + TV +W ++ SL H + V C ++ + I S S + L +
Sbjct: 81 VTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKL----WDK 136
Query: 64 SSTPFGHGSNQSVRHLKYSLFKKS--LLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPAS 121
SS H + + Y F S + + + V +WDV + ++ +H A +
Sbjct: 137 SSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHY-QLHSAAVN 195
Query: 122 GICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVA-DTPLTAVDFMPDGATLAIGSS 179
G+ F P L +T D + + D +L+ TL P T V F G A G S
Sbjct: 196 GLSFHPSGNYL-ITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGS 253
Score = 32.3 bits (72), Expect = 1.2
Identities = 17/69 (24%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEI-ILHSVTT 61
+ + G++NTV +WD+++ R+ + + H V ++++ + Y+ + S + IL +
Sbjct: 164 IAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEG 223
Query: 62 NLSSTPFGH 70
L T GH
Sbjct: 224 RLLYTLHGH 232
>gi|48928050 F-box and WD repeat domain containing 11 isoform C
[Homo sapiens]
Length = 542
Score = 52.0 bits (123), Expect = 1e-06
Identities = 51/217 (23%), Positives = 99/217 (45%), Gaps = 13/217 (5%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTN 62
++SG +N++ IWD S + L H V C+ Y ++ I +GS + + V T
Sbjct: 253 IISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVRVWDVNTG 310
Query: 63 LSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQS--PYHNFDSVHKAPA 120
H N++V HL++S L+ + S + + +WD+ S + H+A
Sbjct: 311 EVLNTLIH-HNEAVLHLRFS---NGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAV 366
Query: 121 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR 180
+ + F ++ V+ D+ I ++ TS+ + V+TL A D ++ GSS
Sbjct: 367 NVVDF---DDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVS-GSSD 422
Query: 181 GKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLT 217
I +D+ + ++ + H+ V+CI F +++
Sbjct: 423 NTIRLWDIE-CGACLRVLEGHEELVRCIRFDNKRIVS 458
Score = 39.3 bits (90), Expect = 0.010
Identities = 31/129 (24%), Positives = 54/129 (41%), Gaps = 13/129 (10%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTT 61
Y+VS + T+ +W + R+L HK + C+ Y D + SGS I L +
Sbjct: 375 YIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQY--RDRLVVSGSSDNTIRLWDIEC 432
Query: 62 NLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPAS 121
G + VR +++ K ++ D G + +WD+ + +APAS
Sbjct: 433 GACLRVL-EGHEELVRCIRFD--NKRIVSGAYD-GKIKVWDLQAALD-------PRAPAS 481
Query: 122 GICFSPVNE 130
+C + E
Sbjct: 482 TLCLRTLVE 490
>gi|13376840 WD repeat domain 61 [Homo sapiens]
Length = 305
Score = 52.0 bits (123), Expect = 1e-06
Identities = 39/146 (26%), Positives = 75/146 (51%), Gaps = 6/146 (4%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVT- 60
YL SG ++ +NI+D+ + ++ +L+ H + +T++ + + + S G I ++ V
Sbjct: 162 YLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQH 221
Query: 61 TNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 120
NL+ T GH S V ++ + + S SD V +WDV +++ H F H+
Sbjct: 222 ANLAGTLSGHAS--WVLNVAFCPDDTHFVSSSSDKS-VKVWDVGTRTCVHTFFD-HQDQV 277
Query: 121 SGICFSPVNELLFVTIGLDKRIILYD 146
G+ ++ N V++G D+ I +YD
Sbjct: 278 WGVKYNG-NGSKIVSVGDDQEIHIYD 302
Score = 49.7 bits (117), Expect = 7e-06
Identities = 47/188 (25%), Positives = 86/188 (45%), Gaps = 7/188 (3%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTT 61
YL +G VNI+ ++S + SL + + Y+ + Y+ASG++ G I + + T
Sbjct: 120 YLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIAT 179
Query: 62 -NLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 120
L T GH +R L +S LL + SD+G + ++DV + S H +
Sbjct: 180 GKLLHTLEGHA--MPIRSLTFSP-DSQLLVTASDDGYIKIYDVQHANLAGTL-SGHASWV 235
Query: 121 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLV-ADTPLTAVDFMPDGATLAIGSS 179
+ F P ++ FV+ DK + ++D ++ V T + V + +G+ +
Sbjct: 236 LNVAFCP-DDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGD 294
Query: 180 RGKIYQYD 187
+I+ YD
Sbjct: 295 DQEIHIYD 302
Score = 48.1 bits (113), Expect = 2e-05
Identities = 47/202 (23%), Positives = 86/202 (42%), Gaps = 6/202 (2%)
Query: 5 SGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTNLS 64
S L+ + +WDL++ + +S+ + ++ + Y+A+G+ G++ + V +
Sbjct: 81 SSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKK 140
Query: 65 STPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGIC 124
+ + + YS K L D GI+ ++D+ + H + H P +
Sbjct: 141 EYSL-DTRGKFILSIAYSPDGKYLASGAID-GIINIFDIATGKLLHTLEG-HAMPIRSLT 197
Query: 125 FSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTP-LTAVDFMPDGATLAIGSSRGKI 183
FSP ++LL VT D I +YD L TL + V F PD SS +
Sbjct: 198 FSPDSQLL-VTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSV 256
Query: 184 YQYDLRMLKSPVKTISAHKTSV 205
+D+ ++ V T H+ V
Sbjct: 257 KVWDVG-TRTCVHTFFDHQDQV 277
>gi|48928048 F-box and WD repeat domain containing 11 isoform A
[Homo sapiens]
Length = 508
Score = 52.0 bits (123), Expect = 1e-06
Identities = 51/217 (23%), Positives = 99/217 (45%), Gaps = 13/217 (5%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTN 62
++SG +N++ IWD S + L H V C+ Y ++ I +GS + + V T
Sbjct: 219 IISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVRVWDVNTG 276
Query: 63 LSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQS--PYHNFDSVHKAPA 120
H N++V HL++S L+ + S + + +WD+ S + H+A
Sbjct: 277 EVLNTLIH-HNEAVLHLRFS---NGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAV 332
Query: 121 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR 180
+ + F ++ V+ D+ I ++ TS+ + V+TL A D ++ GSS
Sbjct: 333 NVVDF---DDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVS-GSSD 388
Query: 181 GKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLT 217
I +D+ + ++ + H+ V+CI F +++
Sbjct: 389 NTIRLWDIE-CGACLRVLEGHEELVRCIRFDNKRIVS 424
Score = 39.3 bits (90), Expect = 0.010
Identities = 31/129 (24%), Positives = 54/129 (41%), Gaps = 13/129 (10%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTT 61
Y+VS + T+ +W + R+L HK + C+ Y D + SGS I L +
Sbjct: 341 YIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQY--RDRLVVSGSSDNTIRLWDIEC 398
Query: 62 NLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPAS 121
G + VR +++ K ++ D G + +WD+ + +APAS
Sbjct: 399 GACLRVL-EGHEELVRCIRFD--NKRIVSGAYD-GKIKVWDLQAALD-------PRAPAS 447
Query: 122 GICFSPVNE 130
+C + E
Sbjct: 448 TLCLRTLVE 456
>gi|48928046 F-box and WD repeat domain containing 11 isoform B
[Homo sapiens]
Length = 529
Score = 52.0 bits (123), Expect = 1e-06
Identities = 51/217 (23%), Positives = 99/217 (45%), Gaps = 13/217 (5%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTN 62
++SG +N++ IWD S + L H V C+ Y ++ I +GS + + V T
Sbjct: 240 IISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVRVWDVNTG 297
Query: 63 LSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQS--PYHNFDSVHKAPA 120
H N++V HL++S L+ + S + + +WD+ S + H+A
Sbjct: 298 EVLNTLIH-HNEAVLHLRFS---NGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAV 353
Query: 121 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR 180
+ + F ++ V+ D+ I ++ TS+ + V+TL A D ++ GSS
Sbjct: 354 NVVDF---DDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVS-GSSD 409
Query: 181 GKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLT 217
I +D+ + ++ + H+ V+CI F +++
Sbjct: 410 NTIRLWDIE-CGACLRVLEGHEELVRCIRFDNKRIVS 445
Score = 39.3 bits (90), Expect = 0.010
Identities = 31/129 (24%), Positives = 54/129 (41%), Gaps = 13/129 (10%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTT 61
Y+VS + T+ +W + R+L HK + C+ Y D + SGS I L +
Sbjct: 362 YIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQY--RDRLVVSGSSDNTIRLWDIEC 419
Query: 62 NLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPAS 121
G + VR +++ K ++ D G + +WD+ + +APAS
Sbjct: 420 GACLRVL-EGHEELVRCIRFD--NKRIVSGAYD-GKIKVWDLQAALD-------PRAPAS 468
Query: 122 GICFSPVNE 130
+C + E
Sbjct: 469 TLCLRTLVE 477
>gi|5803221 WD repeat-containing protein 3 [Homo sapiens]
Length = 943
Score = 51.6 bits (122), Expect = 2e-06
Identities = 46/182 (25%), Positives = 82/182 (45%), Gaps = 5/182 (2%)
Query: 12 VNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPFGHG 71
V IWDL+ L+ K +VTC+ + + ++A G G I + S+ + + F +G
Sbjct: 47 VFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTF-NG 105
Query: 72 SNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPVNEL 131
++ LKY L D I+ +WDV ++S + HK + F L
Sbjct: 106 HKAAITTLKYDQLGGRLASGSKDTDII-VWDVINESGLYRLKG-HKDAITQALFLREKNL 163
Query: 132 LFVTIGLDKRIILYDTSSKKLVKTLVAD-TPLTAVDFMPDGATLAIGSSRGKIYQYDLRM 190
L VT G D + +D ++ KT+V T + + + + L G+S ++ +D+
Sbjct: 164 L-VTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSELRVWDIAY 222
Query: 191 LK 192
L+
Sbjct: 223 LQ 224
Score = 32.7 bits (73), Expect = 0.92
Identities = 27/106 (25%), Positives = 52/106 (49%), Gaps = 2/106 (1%)
Query: 1 MYLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVT 60
++L G + ++ I+ L S + + HK +T + Y+ +ASGS +II+ V
Sbjct: 78 LHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDV- 136
Query: 61 TNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQ 106
N S G ++ + L +K+LL + + +V WD+++Q
Sbjct: 137 INESGLYRLKGHKDAITQALF-LREKNLLVTSGKDTMVKWWDLDTQ 181
Score = 30.0 bits (66), Expect = 6.0
Identities = 22/86 (25%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 116 HKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLA 175
H++ + FS N + V I +++ S+ + ++T+ + L + F+P +
Sbjct: 414 HRSDVRTLSFSSDN--IAVLSAAADSIKIWNRSTLQCIRTMTCEYALCSF-FVPGDRQVV 470
Query: 176 IGSSRGKIYQYDLRMLKSPVKTISAH 201
IG+ GK+ YDL + ++TI AH
Sbjct: 471 IGTKTGKLQLYDLAS-GNLLETIDAH 495
>gi|4502477 beta-transducin repeat containing protein isoform 2
[Homo sapiens]
Length = 569
Score = 51.2 bits (121), Expect = 3e-06
Identities = 51/217 (23%), Positives = 98/217 (45%), Gaps = 13/217 (5%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTN 62
+VSG +NT+ IWD + R L H V C+ Y ++ I +GS + + V T
Sbjct: 280 IVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQY--DERVIITGSSDSTVRVWDVNTG 337
Query: 63 LSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQS--PYHNFDSVHKAPA 120
H ++V HL+ F ++ + S + + +WD+ S + H+A
Sbjct: 338 EMLNTLIHHC-EAVLHLR---FNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAV 393
Query: 121 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR 180
+ + F ++ V+ D+ I +++TS+ + V+TL A D ++ GSS
Sbjct: 394 NVVDF---DDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVS-GSSD 449
Query: 181 GKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLT 217
I +D+ + ++ + H+ V+CI F +++
Sbjct: 450 NTIRLWDIE-CGACLRVLEGHEELVRCIRFDNKRIVS 485
Score = 37.7 bits (86), Expect = 0.029
Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 15/130 (11%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTT 61
Y+VS + T+ +W+ + R+L HK + C+ Y D + SGS I L +
Sbjct: 402 YIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQY--RDRLVVSGSSDNTIRLWDIEC 459
Query: 62 NLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWD-VNSQSPYHNFDSVHKAPA 120
G + VR +++ K ++ D G + +WD V + P +APA
Sbjct: 460 GACLRVL-EGHEELVRCIRFD--NKRIVSGAYD-GKIKVWDLVAALDP--------RAPA 507
Query: 121 SGICFSPVNE 130
+C + E
Sbjct: 508 GTLCLRTLVE 517
>gi|16117783 beta-transducin repeat containing protein isoform 1
[Homo sapiens]
Length = 605
Score = 51.2 bits (121), Expect = 3e-06
Identities = 51/217 (23%), Positives = 98/217 (45%), Gaps = 13/217 (5%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTN 62
+VSG +NT+ IWD + R L H V C+ Y ++ I +GS + + V T
Sbjct: 316 IVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQY--DERVIITGSSDSTVRVWDVNTG 373
Query: 63 LSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQS--PYHNFDSVHKAPA 120
H ++V HL+ F ++ + S + + +WD+ S + H+A
Sbjct: 374 EMLNTLIHHC-EAVLHLR---FNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAV 429
Query: 121 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR 180
+ + F ++ V+ D+ I +++TS+ + V+TL A D ++ GSS
Sbjct: 430 NVVDF---DDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVS-GSSD 485
Query: 181 GKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLT 217
I +D+ + ++ + H+ V+CI F +++
Sbjct: 486 NTIRLWDIE-CGACLRVLEGHEELVRCIRFDNKRIVS 521
Score = 37.7 bits (86), Expect = 0.029
Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 15/130 (11%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTT 61
Y+VS + T+ +W+ + R+L HK + C+ Y D + SGS I L +
Sbjct: 438 YIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQY--RDRLVVSGSSDNTIRLWDIEC 495
Query: 62 NLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWD-VNSQSPYHNFDSVHKAPA 120
G + VR +++ K ++ D G + +WD V + P +APA
Sbjct: 496 GACLRVL-EGHEELVRCIRFD--NKRIVSGAYD-GKIKVWDLVAALDP--------RAPA 543
Query: 121 SGICFSPVNE 130
+C + E
Sbjct: 544 GTLCLRTLVE 553
>gi|32483359 apoptotic peptidase activating factor 1 isoform c [Homo
sapiens]
Length = 1248
Score = 50.4 bits (119), Expect = 4e-06
Identities = 52/238 (21%), Positives = 105/238 (44%), Gaps = 19/238 (7%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEI-ILHSVTT 61
+ S G + T+ ++ ++ +K H+D+V C ++ +D +IA+ S+ ++ I +S+T
Sbjct: 630 IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTG 689
Query: 62 NLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPAS 121
L T H + H S LL + S + + LWD+N Q N H +
Sbjct: 690 ELVHTYDEHSEQVNCCHFTNS-SHHLLLATGSSDCFLKLWDLN-QKECRNTMFGHTNSVN 747
Query: 122 GICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVA--------------DTPLTAVDF 167
FSP ++LL + D + L+D +S K++ + + +
Sbjct: 748 HCRFSPDDKLL-ASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSW 806
Query: 168 MPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKGC 225
DGA + + +++ KI+ +D+ + + H +++Q F L +L++ C
Sbjct: 807 SADGARIMV-AAKNKIFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAVVALSQYC 863
Score = 41.2 bits (95), Expect = 0.003
Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 6/107 (5%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTT 61
++ + ++ V IW+ + + + +H +QV C + + ++ + S + L
Sbjct: 671 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 730
Query: 62 N---LSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNS 105
N +T FGH SV H ++S K LL S S +G + LWD S
Sbjct: 731 NQKECRNTMFGH--TNSVNHCRFSPDDK-LLASCSADGTLKLWDATS 774
Score = 34.3 bits (77), Expect = 0.32
Identities = 41/189 (21%), Positives = 72/189 (38%), Gaps = 11/189 (5%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTN 62
L+S + TV +W++ + + H+ V + + +S S + S
Sbjct: 1058 LLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLL 1117
Query: 63 LSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYH-------NFDSV 115
L G N VR +S+ +LL + DNG + +W+V++ H +
Sbjct: 1118 LPLHEL-RGHNGCVRCSAFSV-DSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAAT 1175
Query: 116 HKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLA 175
H + +CFSP ++L G K + S + T T L + PD T
Sbjct: 1176 HGGWVTDLCFSPDGKMLISAGGYIKWWNVVTGESSQTFYT--NGTNLKKIHVSPDFKTYV 1233
Query: 176 IGSSRGKIY 184
+ G +Y
Sbjct: 1234 TVDNLGILY 1242
>gi|7108333 apoptotic peptidase activating factor 1 isoform a [Homo
sapiens]
Length = 1237
Score = 50.4 bits (119), Expect = 4e-06
Identities = 52/238 (21%), Positives = 105/238 (44%), Gaps = 19/238 (7%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEI-ILHSVTT 61
+ S G + T+ ++ ++ +K H+D+V C ++ +D +IA+ S+ ++ I +S+T
Sbjct: 619 IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTG 678
Query: 62 NLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPAS 121
L T H + H S LL + S + + LWD+N Q N H +
Sbjct: 679 ELVHTYDEHSEQVNCCHFTNS-SHHLLLATGSSDCFLKLWDLN-QKECRNTMFGHTNSVN 736
Query: 122 GICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVA--------------DTPLTAVDF 167
FSP ++LL + D + L+D +S K++ + + +
Sbjct: 737 HCRFSPDDKLL-ASCSADGTLKLWDATSANERKSINVKQFFLNLEDPQEDMEVIVKCCSW 795
Query: 168 MPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTVLTKSSLNKGC 225
DGA + + +++ KI+ +D+ + + H +++Q F L +L++ C
Sbjct: 796 SADGARIMV-AAKNKIFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLAVVALSQYC 852
Score = 41.2 bits (95), Expect = 0.003
Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 6/107 (5%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTT 61
++ + ++ V IW+ + + + +H +QV C + + ++ + S + L
Sbjct: 660 FIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDL 719
Query: 62 N---LSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNS 105
N +T FGH SV H ++S K LL S S +G + LWD S
Sbjct: 720 NQKECRNTMFGH--TNSVNHCRFSPDDK-LLASCSADGTLKLWDATS 763
Score = 34.3 bits (77), Expect = 0.32
Identities = 41/189 (21%), Positives = 72/189 (38%), Gaps = 11/189 (5%)
Query: 3 LVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTN 62
L+S + TV +W++ + + H+ V + + +S S + S
Sbjct: 1047 LLSWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLL 1106
Query: 63 LSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYH-------NFDSV 115
L G N VR +S+ +LL + DNG + +W+V++ H +
Sbjct: 1107 LPLHEL-RGHNGCVRCSAFSV-DSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAAT 1164
Query: 116 HKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLA 175
H + +CFSP ++L G K + S + T T L + PD T
Sbjct: 1165 HGGWVTDLCFSPDGKMLISAGGYIKWWNVVTGESSQTFYT--NGTNLKKIHVSPDFKTYV 1222
Query: 176 IGSSRGKIY 184
+ G +Y
Sbjct: 1223 TVDNLGILY 1231
>gi|50980309 UTP15, U3 small nucleolar ribonucleoprotein, homolog
[Homo sapiens]
Length = 518
Score = 49.7 bits (117), Expect = 7e-06
Identities = 42/205 (20%), Positives = 87/205 (42%), Gaps = 4/205 (1%)
Query: 9 NNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPF 68
++ ++I+ S+ ++ KD C T+ + + +GS G + L ++ F
Sbjct: 59 SSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGRLLVAGSEDGGVQLFDISGRAPLRQF 118
Query: 69 GHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFSPV 128
G ++V + ++ K ++ S +D+ V LWD+ + F H C S +
Sbjct: 119 -EGHTKAVHTVDFTADKYHVV-SGADDYTVKLWDIPNSKEILTFKE-HSDYVRCGCASKL 175
Query: 129 NELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSRGKIYQYDL 188
N LF+T D + ++D + + V ++ P+ +V P G L R + +D+
Sbjct: 176 NPDLFITGSYDHTVKMFDARTSESVLSVEHGQPVESVLLFPSGGLLVSAGGR-YVKVWDM 234
Query: 189 RMLKSPVKTISAHKTSVQCIAFQYS 213
+ ++ H +V C+ S
Sbjct: 235 LKGGQLLVSLKNHHKTVTCLCLSSS 259
Score = 46.6 bits (109), Expect = 6e-05
Identities = 41/181 (22%), Positives = 77/181 (42%), Gaps = 6/181 (3%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTC-VTYNWNDCYIASGSLSGEIILHSVT 60
++VSG + TV +WD+ + + + K+H D V C N +GS + +
Sbjct: 136 HVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPDLFITGSYDHTVKMFDAR 195
Query: 61 TNLSSTPFGHGSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 120
T+ S HG Q V + LF L + V +WD+ H
Sbjct: 196 TSESVLSVEHG--QPVESV--LLFPSGGLLVSAGGRYVKVWDMLKGGQLLVSLKNHHKTV 251
Query: 121 SGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSR 180
+ +C S + L ++ LD+++ +Y T+S K+V + + ++ + T+ +G +
Sbjct: 252 TCLCLSSSGQRL-LSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALAHEDETIVVGMTN 310
Query: 181 G 181
G
Sbjct: 311 G 311
>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
sapiens]
Length = 390
Score = 49.3 bits (116), Expect = 1e-05
Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 4/85 (4%)
Query: 71 GSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDV---NSQSPYHNFDSVHKAPASGICFSP 127
G V + + L +SL GSV+D+ + +WD N+ P H+ D+ H A + + F+P
Sbjct: 190 GHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDA-HTAEVNCLSFNP 248
Query: 128 VNELLFVTIGLDKRIILYDTSSKKL 152
+E + T DK + L+D + KL
Sbjct: 249 YSEFILATGSADKTVALWDLRNLKL 273
Score = 43.9 bits (102), Expect = 4e-04
Identities = 49/199 (24%), Positives = 90/199 (45%), Gaps = 21/199 (10%)
Query: 28 DHKDQVTCVTYN-WNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVR---HLK--Y 81
+H+ +V Y N C IA+ + S ++++ T + S N +R H K Y
Sbjct: 87 NHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGY 146
Query: 82 SL-FKKSLLG---SVSDNGIVTLWDVNSQSPYHNFDSV------HKAPASGICFSPVNEL 131
L + +L G S SD+ + LWD+++ H A + + ++E
Sbjct: 147 GLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHES 206
Query: 132 LFVTIGLDKRIILYDTSSKKLVK---TLVADT-PLTAVDFMP-DGATLAIGSSRGKIYQY 186
LF ++ D++++++DT S K ++ A T + + F P LA GS+ + +
Sbjct: 207 LFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALW 266
Query: 187 DLRMLKSPVKTISAHKTSV 205
DLR LK + + +HK +
Sbjct: 267 DLRNLKLKLHSFESHKDEI 285
Score = 43.9 bits (102), Expect = 4e-04
Identities = 39/158 (24%), Positives = 74/158 (46%), Gaps = 12/158 (7%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDC--YIASGSLSGEI----- 54
+L+S ++T+ +WD+ + + D K T T D ++ SL G +
Sbjct: 157 HLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQK 216
Query: 55 -ILHSVTTNLSSTPFGH--GSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDV-NSQSPYH 110
++ +N +S P V L ++ + + +L + S + V LWD+ N + H
Sbjct: 217 LMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLH 276
Query: 111 NFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTS 148
+F+S HK + +SP NE + + G D+R+ ++D S
Sbjct: 277 SFES-HKDEIFQVQWSPHNETILASSGTDRRLNVWDLS 313
>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
sapiens]
Length = 424
Score = 49.3 bits (116), Expect = 1e-05
Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 4/85 (4%)
Query: 71 GSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDV---NSQSPYHNFDSVHKAPASGICFSP 127
G V + + L +SL GSV+D+ + +WD N+ P H+ D+ H A + + F+P
Sbjct: 224 GHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDA-HTAEVNCLSFNP 282
Query: 128 VNELLFVTIGLDKRIILYDTSSKKL 152
+E + T DK + L+D + KL
Sbjct: 283 YSEFILATGSADKTVALWDLRNLKL 307
Score = 43.9 bits (102), Expect = 4e-04
Identities = 49/199 (24%), Positives = 90/199 (45%), Gaps = 21/199 (10%)
Query: 28 DHKDQVTCVTYN-WNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVR---HLK--Y 81
+H+ +V Y N C IA+ + S ++++ T + S N +R H K Y
Sbjct: 121 NHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEGY 180
Query: 82 SL-FKKSLLG---SVSDNGIVTLWDVNSQSPYHNFDSV------HKAPASGICFSPVNEL 131
L + +L G S SD+ + LWD+++ H A + + ++E
Sbjct: 181 GLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHES 240
Query: 132 LFVTIGLDKRIILYDTSSKKLVK---TLVADT-PLTAVDFMP-DGATLAIGSSRGKIYQY 186
LF ++ D++++++DT S K ++ A T + + F P LA GS+ + +
Sbjct: 241 LFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALW 300
Query: 187 DLRMLKSPVKTISAHKTSV 205
DLR LK + + +HK +
Sbjct: 301 DLRNLKLKLHSFESHKDEI 319
Score = 43.9 bits (102), Expect = 4e-04
Identities = 39/158 (24%), Positives = 74/158 (46%), Gaps = 12/158 (7%)
Query: 2 YLVSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDC--YIASGSLSGEI----- 54
+L+S ++T+ +WD+ + + D K T T D ++ SL G +
Sbjct: 191 HLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHESLFGSVADDQK 250
Query: 55 -ILHSVTTNLSSTPFGH--GSNQSVRHLKYSLFKKSLLGSVSDNGIVTLWDV-NSQSPYH 110
++ +N +S P V L ++ + + +L + S + V LWD+ N + H
Sbjct: 251 LMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLH 310
Query: 111 NFDSVHKAPASGICFSPVNELLFVTIGLDKRIILYDTS 148
+F+S HK + +SP NE + + G D+R+ ++D S
Sbjct: 311 SFES-HKDEIFQVQWSPHNETILASSGTDRRLNVWDLS 347
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,716,085
Number of Sequences: 37866
Number of extensions: 931459
Number of successful extensions: 3750
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 104
Number of HSP's successfully gapped in prelim test: 189
Number of HSP's that attempted gapping in prelim test: 3077
Number of HSP's gapped (non-prelim): 760
length of query: 571
length of database: 18,247,518
effective HSP length: 108
effective length of query: 463
effective length of database: 14,157,990
effective search space: 6555149370
effective search space used: 6555149370
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.