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Search of human proteins with 20357578
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20357578 apobec-1 complementation factor isoform 3 [Homo
sapiens]
(594 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20357578 apobec-1 complementation factor isoform 3 [Homo sapi... 1198 0.0
gi|20357572 apobec-1 complementation factor isoform 1 [Homo sapi... 1121 0.0
gi|20357575 apobec-1 complementation factor isoform 2 [Homo sapi... 1114 0.0
gi|148833513 RNA binding motif protein 47 isoform a [Homo sapiens] 493 e-139
gi|148833511 RNA binding motif protein 47 isoform b [Homo sapiens] 455 e-128
gi|21450675 RNA binding motif protein 46 [Homo sapiens] 438 e-123
gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4... 319 5e-87
gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2 [... 319 5e-87
gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting ... 318 1e-86
gi|228008396 synaptotagmin binding, cytoplasmic RNA interacting ... 318 1e-86
gi|228008293 synaptotagmin binding, cytoplasmic RNA interacting ... 318 1e-86
gi|228008291 synaptotagmin binding, cytoplasmic RNA interacting ... 318 1e-86
gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3... 313 2e-85
gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1... 313 2e-85
gi|228008398 synaptotagmin binding, cytoplasmic RNA interacting ... 268 1e-71
gi|228008295 synaptotagmin binding, cytoplasmic RNA interacting ... 268 1e-71
gi|34740339 dead end homolog 1 [Homo sapiens] 167 2e-41
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 86 7e-17
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 73 6e-13
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 73 6e-13
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 73 6e-13
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 70 5e-12
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 69 9e-12
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens] 67 4e-11
gi|55956788 nucleolin [Homo sapiens] 64 3e-10
gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo sa... 64 5e-10
gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo s... 60 4e-09
gi|51948366 ribonucleoprotein, PTB-binding 2 [Homo sapiens] 60 6e-09
gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 58 2e-08
gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 58 2e-08
>gi|20357578 apobec-1 complementation factor isoform 3 [Homo
sapiens]
Length = 594
Score = 1198 bits (3100), Expect = 0.0
Identities = 594/594 (100%), Positives = 594/594 (100%)
Query: 1 MEAVCLGTCPEPEASMSTAIPGLKKGNNALQSIILQTLLEKENGQRKYGGPPPGWDAAPP 60
MEAVCLGTCPEPEASMSTAIPGLKKGNNALQSIILQTLLEKENGQRKYGGPPPGWDAAPP
Sbjct: 1 MEAVCLGTCPEPEASMSTAIPGLKKGNNALQSIILQTLLEKENGQRKYGGPPPGWDAAPP 60
Query: 61 ERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNA 120
ERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNA
Sbjct: 61 ERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNA 120
Query: 121 IKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSA 180
IKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSA
Sbjct: 121 IKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSA 180
Query: 181 ADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKI 240
ADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKI
Sbjct: 181 ADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKI 240
Query: 241 LYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLD 300
LYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLD
Sbjct: 241 LYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLD 300
Query: 301 GSPIEVTLAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQT 360
GSPIEVTLAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQT
Sbjct: 301 GSPIEVTLAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQT 360
Query: 361 YAAIPSLHFPATKGHLSNRAIIRAPSVRGAAGVRGLGGRGYLAYTGLGRGYQVKGDKRED 420
YAAIPSLHFPATKGHLSNRAIIRAPSVRGAAGVRGLGGRGYLAYTGLGRGYQVKGDKRED
Sbjct: 361 YAAIPSLHFPATKGHLSNRAIIRAPSVRGAAGVRGLGGRGYLAYTGLGRGYQVKGDKRED 420
Query: 421 KLYDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFL 480
KLYDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFL
Sbjct: 421 KLYDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFL 480
Query: 481 YKITIPALASQNPAIHPFTPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAA 540
YKITIPALASQNPAIHPFTPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAA
Sbjct: 481 YKITIPALASQNPAIHPFTPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAA 540
Query: 541 TAFPGYAVPNATAPVSAAQLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF 594
TAFPGYAVPNATAPVSAAQLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF
Sbjct: 541 TAFPGYAVPNATAPVSAAQLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF 594
>gi|20357572 apobec-1 complementation factor isoform 1 [Homo
sapiens]
Length = 586
Score = 1121 bits (2900), Expect = 0.0
Identities = 557/568 (98%), Positives = 563/568 (99%), Gaps = 2/568 (0%)
Query: 29 ALQSIILQT--LLEKENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEK 86
AL++++ +T L +ENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEK
Sbjct: 19 ALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEK 78
Query: 87 IGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRL 146
IGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRL
Sbjct: 79 IGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRL 138
Query: 147 FVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRK 206
FVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRK
Sbjct: 139 FVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRK 198
Query: 207 LLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGA 266
LLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGA
Sbjct: 199 LLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGA 258
Query: 267 VERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGG 326
VERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGG
Sbjct: 259 VERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGG 318
Query: 327 RGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRAPS 386
RGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRAPS
Sbjct: 319 RGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRAPS 378
Query: 387 VRGAAGVRGLGGRGYLAYTGLGRGYQVKGDKREDKLYDILPGMELTPMNPVTLKPQGIKL 446
VRGAAGVRGLGGRGYLAYTGLGRGYQVKGDKREDKLYDILPGMELTPMNPVTLKPQGIKL
Sbjct: 379 VRGAAGVRGLGGRGYLAYTGLGRGYQVKGDKREDKLYDILPGMELTPMNPVTLKPQGIKL 438
Query: 447 APQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKITIPALASQNPAIHPFTPPKLSAF 506
APQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKITIPALASQNPAIHPFTPPKLSAF
Sbjct: 439 APQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKITIPALASQNPAIHPFTPPKLSAF 498
Query: 507 VDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAATAFPGYAVPNATAPVSAAQLKQAVTL 566
VDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAATAFPGYAVPNATAPVSAAQLKQAVTL
Sbjct: 499 VDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAATAFPGYAVPNATAPVSAAQLKQAVTL 558
Query: 567 GQDLAAYTTYEVYPTFAVTARGDGYGTF 594
GQDLAAYTTYEVYPTFAVTARGDGYGTF
Sbjct: 559 GQDLAAYTTYEVYPTFAVTARGDGYGTF 586
>gi|20357575 apobec-1 complementation factor isoform 2 [Homo
sapiens]
Length = 594
Score = 1114 bits (2881), Expect = 0.0
Identities = 557/576 (96%), Positives = 563/576 (97%), Gaps = 10/576 (1%)
Query: 29 ALQSIILQT--LLEKENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEK 86
AL++++ +T L +ENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEK
Sbjct: 19 ALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEK 78
Query: 87 IGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRL 146
IGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRL
Sbjct: 79 IGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRL 138
Query: 147 FVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRK 206
FVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRK
Sbjct: 139 FVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRK 198
Query: 207 LLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGA 266
LLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGA
Sbjct: 199 LLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGA 258
Query: 267 VERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGG 326
VERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGG
Sbjct: 259 VERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGG 318
Query: 327 RGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRAPS 386
RGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRAPS
Sbjct: 319 RGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRAPS 378
Query: 387 VR--------GAAGVRGLGGRGYLAYTGLGRGYQVKGDKREDKLYDILPGMELTPMNPVT 438
VR GAAGVRGLGGRGYLAYTGLGRGYQVKGDKREDKLYDILPGMELTPMNPVT
Sbjct: 379 VREIYMNVPVGAAGVRGLGGRGYLAYTGLGRGYQVKGDKREDKLYDILPGMELTPMNPVT 438
Query: 439 LKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKITIPALASQNPAIHPF 498
LKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKITIPALASQNPAIHPF
Sbjct: 439 LKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKITIPALASQNPAIHPF 498
Query: 499 TPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAATAFPGYAVPNATAPVSAA 558
TPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAATAFPGYAVPNATAPVSAA
Sbjct: 499 TPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAATAFPGYAVPNATAPVSAA 558
Query: 559 QLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF 594
QLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF
Sbjct: 559 QLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF 594
>gi|148833513 RNA binding motif protein 47 isoform a [Homo sapiens]
Length = 593
Score = 493 bits (1270), Expect = e-139
Identities = 271/550 (49%), Positives = 339/550 (61%), Gaps = 71/550 (12%)
Query: 41 KENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFN 100
+ENGQRKYGGPPPGW+ P+RGCE+F+GK+PRD++EDEL+P+ E +G+IYE+R+MMDF+
Sbjct: 48 QENGQRKYGGPPPGWEGPHPQRGCEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFD 107
Query: 101 GNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEI 160
G NRGYAFV + +K EAK A+++LNNYEIR GRLLGVC SVDNCRLF+GGIPK KKREEI
Sbjct: 108 GKNRGYAFVMYCHKHEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEI 167
Query: 161 LSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIA 220
L E+ KVTEGV+DVIVY SAADK KNRGFAFVEYESHRAAAMARRKL+PGRIQLWGH IA
Sbjct: 168 LEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIA 227
Query: 221 VDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVH 280
VDWAEPE++VDED M +VKILYVRNLM+ T+E+ I+K F PG VERVKKIRDYAFVH
Sbjct: 228 VDWAEPEIDVDEDVMETVKILYVRNLMIETTEDTIKKSFGQFNPGCVERVKKIRDYAFVH 287
Query: 281 FSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRY---TRGTGGRGTMLQGEYTY 337
F++REDAV AM LNG L+GS +EVTLAKPVDK+ Y RY RG G Q Y Y
Sbjct: 288 FTSREDAVHAMNNLNGTELEGSCLEVTLAKPVDKEQYSRYQKAARGGGAAEAAQQPSYVY 347
Query: 338 SLGQVYDP-TTTYLGAPVFYAPQTYAAI--PSLHFPATKGHLSNRAIIRAPSVRGAAGVR 394
S DP T Y G P Y A+ P+ + G + R RGAAG R
Sbjct: 348 SC----DPYTLAYYGYP-------YNALIGPNRDYFVKAGSIRGRG-------RGAAGNR 389
Query: 395 GLGGRG-YLAYTGLGRG----YQVKGDKREDKLYDILPGMELTPMNPVTLKPQGIKLAPQ 449
G RG YL GRG Y K+++K Y+++P +E+ +NPV +KP
Sbjct: 390 APGPRGSYLGGYSAGRGIYSRYHEGKGKQQEKGYELVPNLEIPTVNPVAIKPG------- 442
Query: 450 ILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKITIPALASQNPAIHPFTPPKLSAFVDE 509
+ IPA+ +Q PK+ +++
Sbjct: 443 --------------------------------TVAIPAIGAQYSMFPAAPAPKM---IED 467
Query: 510 AKTYAAEYTLQTLGIPTDGGDGTMATAAAAATAFPGYAVPNATAPVSAAQLKQAVTLGQD 569
K + E+ + + + D A AAAAA A + P + T+ +
Sbjct: 468 GKIHTVEHMISPIAVQPDPASAAAAAAAAAAAAAAVIPTVSTPPPFQGRPITPVYTVAPN 527
Query: 570 LAAYTTYEVY 579
+ T +Y
Sbjct: 528 VQRIPTAGIY 537
>gi|148833511 RNA binding motif protein 47 isoform b [Homo sapiens]
Length = 524
Score = 455 bits (1170), Expect = e-128
Identities = 221/317 (69%), Positives = 257/317 (81%), Gaps = 8/317 (2%)
Query: 41 KENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFN 100
+ENGQRKYGGPPPGW+ P+RGCE+F+GK+PRD++EDEL+P+ E +G+IYE+R+MMDF+
Sbjct: 48 QENGQRKYGGPPPGWEGPHPQRGCEVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFD 107
Query: 101 GNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEI 160
G NRGYAFV + +K EAK A+++LNNYEIR GRLLGVC SVDNCRLF+GGIPK KKREEI
Sbjct: 108 GKNRGYAFVMYCHKHEAKRAVRELNNYEIRPGRLLGVCCSVDNCRLFIGGIPKMKKREEI 167
Query: 161 LSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIA 220
L E+ KVTEGV+DVIVY SAADK KNRGFAFVEYESHRAAAMARRKL+PGRIQLWGH IA
Sbjct: 168 LEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAAMARRKLMPGRIQLWGHQIA 227
Query: 221 VDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVH 280
VDWAEPE++VDED M +VKILYVRNLM+ T+E+ I+K F PG VERVKKIRDYAFVH
Sbjct: 228 VDWAEPEIDVDEDVMETVKILYVRNLMIETTEDTIKKSFGQFNPGCVERVKKIRDYAFVH 287
Query: 281 FSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRY---TRGTGGRGTMLQGEYTY 337
F++REDAV AM LNG L+GS +EVTLAKPVDK+ Y RY RG G Q Y Y
Sbjct: 288 FTSREDAVHAMNNLNGTELEGSCLEVTLAKPVDKEQYSRYQKAARGGGAAEAAQQPSYVY 347
Query: 338 SLGQVYDP-TTTYLGAP 353
S DP T Y G P
Sbjct: 348 SC----DPYTLAYYGYP 360
>gi|21450675 RNA binding motif protein 46 [Homo sapiens]
Length = 533
Score = 438 bits (1127), Expect = e-123
Identities = 203/276 (73%), Positives = 240/276 (86%)
Query: 41 KENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFN 100
+ENGQRK+GGPPPGW+ PP RGCE+F+GK+PRD++EDEL+P+ E+ GKIYE R+MM+F+
Sbjct: 38 QENGQRKFGGPPPGWEGPPPPRGCEVFVGKIPRDMYEDELVPVFERAGKIYEFRLMMEFS 97
Query: 101 GNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEI 160
G NRGYAFV ++ K EA+ AI+ LNNYEIR G+ +GVC S+DNCRLF+G IPK KK+EEI
Sbjct: 98 GENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCVSLDNCRLFIGAIPKEKKKEEI 157
Query: 161 LSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIA 220
L EMKKVTEGVVDVIVYPSA DKTKNRGFAFVEYESHRAAAMARRKL+PG QLWGH I
Sbjct: 158 LDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRAAAMARRKLIPGTFQLWGHTIQ 217
Query: 221 VDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVH 280
VDWA+PE EVDE+TM VK+LYVRNLM+ST+EE I+ EFN KPGAVERVKK+RDYAFVH
Sbjct: 218 VDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEFNKFKPGAVERVKKLRDYAFVH 277
Query: 281 FSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDS 316
F NREDAV AM +NGK +DG+ IEVTLAKPV+K++
Sbjct: 278 FFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKEN 313
Score = 75.5 bits (184), Expect = 1e-13
Identities = 39/97 (40%), Positives = 56/97 (57%), Gaps = 2/97 (2%)
Query: 423 YDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYK 482
Y PG +LTP++ +LK A L+ C KNNW P Y L+S QD + L +YK
Sbjct: 370 YPFYPGTKLTPISMYSLKSNHFNSAVMHLDYYCNKNNWAPPEYYLYSTTSQDGKVLLVYK 429
Query: 483 ITIPALASQNPAIHPFTPPKLSAFVDEAKTYAAEYTL 519
I IPA+A+ + + F P KL +++AK AA++TL
Sbjct: 430 IVIPAIANGSQSY--FMPDKLCTTLEDAKELAAQFTL 464
>gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4
[Homo sapiens]
Length = 532
Score = 319 bits (817), Expect = 5e-87
Identities = 157/300 (52%), Positives = 210/300 (70%), Gaps = 5/300 (1%)
Query: 39 LEKENGQRKYGGPPPG--WDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMM 96
L+ GQRKYGGPPP + P G E+F+GK+PRDL+EDEL+PL EK G I+++R+M
Sbjct: 37 LDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLM 96
Query: 97 MD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTK 155
MD +G NRGYAF+TF K A+ A+K ++YEIR G+ LGVC SV N RLFVG IPK K
Sbjct: 97 MDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISVANNRLFVGSIPKNK 156
Query: 156 KREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLW 215
+E IL E KVTEG+VDVI+Y DK KNRGF F+EYE H++AA ARR+L+ G++++W
Sbjct: 157 TKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVW 216
Query: 216 GHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD 275
G+ + V+WA+P E D + M+ VK+L+VRNL + +EE++EK F+ G +ERVKK++D
Sbjct: 217 GNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEF--GKLERVKKLKD 274
Query: 276 YAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRGTMLQGEY 335
YAFVHF +R AV+AM +NGK ++G IE+ LAKP DK R R T + Y
Sbjct: 275 YAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASRSTAYEDYY 334
>gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2
[Homo sapiens]
Length = 633
Score = 319 bits (817), Expect = 5e-87
Identities = 157/300 (52%), Positives = 210/300 (70%), Gaps = 5/300 (1%)
Query: 39 LEKENGQRKYGGPPPG--WDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMM 96
L+ GQRKYGGPPP + P G E+F+GK+PRDL+EDEL+PL EK G I+++R+M
Sbjct: 138 LDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLM 197
Query: 97 MD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTK 155
MD +G NRGYAF+TF K A+ A+K ++YEIR G+ LGVC SV N RLFVG IPK K
Sbjct: 198 MDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISVANNRLFVGSIPKNK 257
Query: 156 KREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLW 215
+E IL E KVTEG+VDVI+Y DK KNRGF F+EYE H++AA ARR+L+ G++++W
Sbjct: 258 TKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKVKVW 317
Query: 216 GHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD 275
G+ + V+WA+P E D + M+ VK+L+VRNL + +EE++EK F+ G +ERVKK++D
Sbjct: 318 GNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEF--GKLERVKKLKD 375
Query: 276 YAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRGTMLQGEY 335
YAFVHF +R AV+AM +NGK ++G IE+ LAKP DK R R T + Y
Sbjct: 376 YAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASRSTAYEDYY 435
>gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 6 [Homo sapiens]
Length = 562
Score = 318 bits (814), Expect = 1e-86
Identities = 172/381 (45%), Positives = 232/381 (60%), Gaps = 13/381 (3%)
Query: 39 LEKENGQRKYGGPPPG--WDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMM 96
L+ GQRKYGGPPP + P G EIF+GK+PRDLFEDEL+PL EK G I+++R+M
Sbjct: 135 LDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLM 194
Query: 97 MD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTK 155
MD G NRGYAFVTF K A+ A+K NN+EIR+G+ +GVC SV N RLFVG IPK+K
Sbjct: 195 MDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSK 254
Query: 156 KREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLW 215
+E+IL E KVTEG+ DVI+Y DK KNRGF F+EYE H+ AA ARR+L+ G++++W
Sbjct: 255 TKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVW 314
Query: 216 GHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD 275
G+ V+WA+P + D + M+ VK+L+VRNL + +EE++EK F+ G +ERVKK++D
Sbjct: 315 GNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQF--GKLERVKKLKD 372
Query: 276 YAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRGTMLQGEY 335
YAF+HF R+ AV+AM+ +NGK L+G IE+ AKP D+ R + + M Y
Sbjct: 373 YAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYY 432
Query: 336 TYSLGQVYDPTT--------TYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRAPSV 387
Y + PT Y P +Y + Y + +G +
Sbjct: 433 YYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQ 492
Query: 388 RGAAGVRGLGGRGYLAYTGLG 408
GA G G G RG G G
Sbjct: 493 VGARGRGGRGARGAAPSRGRG 513
>gi|228008396 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 2 [Homo sapiens]
Length = 464
Score = 318 bits (814), Expect = 1e-86
Identities = 172/381 (45%), Positives = 232/381 (60%), Gaps = 13/381 (3%)
Query: 39 LEKENGQRKYGGPPPG--WDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMM 96
L+ GQRKYGGPPP + P G EIF+GK+PRDLFEDEL+PL EK G I+++R+M
Sbjct: 37 LDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLM 96
Query: 97 MD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTK 155
MD G NRGYAFVTF K A+ A+K NN+EIR+G+ +GVC SV N RLFVG IPK+K
Sbjct: 97 MDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSK 156
Query: 156 KREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLW 215
+E+IL E KVTEG+ DVI+Y DK KNRGF F+EYE H+ AA ARR+L+ G++++W
Sbjct: 157 TKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVW 216
Query: 216 GHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD 275
G+ V+WA+P + D + M+ VK+L+VRNL + +EE++EK F+ G +ERVKK++D
Sbjct: 217 GNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQF--GKLERVKKLKD 274
Query: 276 YAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRGTMLQGEY 335
YAF+HF R+ AV+AM+ +NGK L+G IE+ AKP D+ R + + M Y
Sbjct: 275 YAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYY 334
Query: 336 TYSLGQVYDPTT--------TYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRAPSV 387
Y + PT Y P +Y + Y + +G +
Sbjct: 335 YYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQ 394
Query: 388 RGAAGVRGLGGRGYLAYTGLG 408
GA G G G RG G G
Sbjct: 395 VGARGRGGRGARGAAPSRGRG 415
>gi|228008293 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 5 [Homo sapiens]
Length = 561
Score = 318 bits (814), Expect = 1e-86
Identities = 172/381 (45%), Positives = 232/381 (60%), Gaps = 13/381 (3%)
Query: 39 LEKENGQRKYGGPPPG--WDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMM 96
L+ GQRKYGGPPP + P G EIF+GK+PRDLFEDEL+PL EK G I+++R+M
Sbjct: 135 LDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLM 194
Query: 97 MD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTK 155
MD G NRGYAFVTF K A+ A+K NN+EIR+G+ +GVC SV N RLFVG IPK+K
Sbjct: 195 MDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSK 254
Query: 156 KREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLW 215
+E+IL E KVTEG+ DVI+Y DK KNRGF F+EYE H+ AA ARR+L+ G++++W
Sbjct: 255 TKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVW 314
Query: 216 GHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD 275
G+ V+WA+P + D + M+ VK+L+VRNL + +EE++EK F+ G +ERVKK++D
Sbjct: 315 GNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQF--GKLERVKKLKD 372
Query: 276 YAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRGTMLQGEY 335
YAF+HF R+ AV+AM+ +NGK L+G IE+ AKP D+ R + + M Y
Sbjct: 373 YAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYY 432
Query: 336 TYSLGQVYDPTT--------TYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRAPSV 387
Y + PT Y P +Y + Y + +G +
Sbjct: 433 YYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQ 492
Query: 388 RGAAGVRGLGGRGYLAYTGLG 408
GA G G G RG G G
Sbjct: 493 VGARGRGGRGARGAAPSRGRG 513
>gi|228008291 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 1 [Homo sapiens]
Length = 623
Score = 318 bits (814), Expect = 1e-86
Identities = 172/381 (45%), Positives = 232/381 (60%), Gaps = 13/381 (3%)
Query: 39 LEKENGQRKYGGPPPG--WDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMM 96
L+ GQRKYGGPPP + P G EIF+GK+PRDLFEDEL+PL EK G I+++R+M
Sbjct: 135 LDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLM 194
Query: 97 MD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTK 155
MD G NRGYAFVTF K A+ A+K NN+EIR+G+ +GVC SV N RLFVG IPK+K
Sbjct: 195 MDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSK 254
Query: 156 KREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLW 215
+E+IL E KVTEG+ DVI+Y DK KNRGF F+EYE H+ AA ARR+L+ G++++W
Sbjct: 255 TKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVW 314
Query: 216 GHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD 275
G+ V+WA+P + D + M+ VK+L+VRNL + +EE++EK F+ G +ERVKK++D
Sbjct: 315 GNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQF--GKLERVKKLKD 372
Query: 276 YAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRGTMLQGEY 335
YAF+HF R+ AV+AM+ +NGK L+G IE+ AKP D+ R + + M Y
Sbjct: 373 YAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYY 432
Query: 336 TYSLGQVYDPTT--------TYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRAPSV 387
Y + PT Y P +Y + Y + +G +
Sbjct: 433 YYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQ 492
Query: 388 RGAAGVRGLGGRGYLAYTGLG 408
GA G G G RG G G
Sbjct: 493 VGARGRGGRGARGAAPSRGRG 513
>gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3
[Homo sapiens]
Length = 535
Score = 313 bits (803), Expect = 2e-85
Identities = 157/303 (51%), Positives = 210/303 (69%), Gaps = 8/303 (2%)
Query: 39 LEKENGQRKYGGPPPG--WDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMM 96
L+ GQRKYGGPPP + P G E+F+GK+PRDL+EDEL+PL EK G I+++R+M
Sbjct: 37 LDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLM 96
Query: 97 MD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTK 155
MD +G NRGYAF+TF K A+ A+K ++YEIR G+ LGVC SV N RLFVG IPK K
Sbjct: 97 MDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISVANNRLFVGSIPKNK 156
Query: 156 KREEILSEMKKVT---EGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRI 212
+E IL E KVT EG+VDVI+Y DK KNRGF F+EYE H++AA ARR+L+ G++
Sbjct: 157 TKENILEEFSKVTGLTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKV 216
Query: 213 QLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKK 272
++WG+ + V+WA+P E D + M+ VK+L+VRNL + +EE++EK F+ G +ERVKK
Sbjct: 217 KVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEF--GKLERVKK 274
Query: 273 IRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRGTMLQ 332
++DYAFVHF +R AV+AM +NGK ++G IE+ LAKP DK R R T +
Sbjct: 275 LKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASRSTAYE 334
Query: 333 GEY 335
Y
Sbjct: 335 DYY 337
>gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1
[Homo sapiens]
Length = 636
Score = 313 bits (803), Expect = 2e-85
Identities = 157/303 (51%), Positives = 210/303 (69%), Gaps = 8/303 (2%)
Query: 39 LEKENGQRKYGGPPPG--WDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMM 96
L+ GQRKYGGPPP + P G E+F+GK+PRDL+EDEL+PL EK G I+++R+M
Sbjct: 138 LDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVPLFEKAGPIWDLRLM 197
Query: 97 MD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTK 155
MD +G NRGYAF+TF K A+ A+K ++YEIR G+ LGVC SV N RLFVG IPK K
Sbjct: 198 MDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISVANNRLFVGSIPKNK 257
Query: 156 KREEILSEMKKVT---EGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRI 212
+E IL E KVT EG+VDVI+Y DK KNRGF F+EYE H++AA ARR+L+ G++
Sbjct: 258 TKENILEEFSKVTGLTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAAQARRRLMSGKV 317
Query: 213 QLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKK 272
++WG+ + V+WA+P E D + M+ VK+L+VRNL + +EE++EK F+ G +ERVKK
Sbjct: 318 KVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSEF--GKLERVKK 375
Query: 273 IRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRGTMLQ 332
++DYAFVHF +R AV+AM +NGK ++G IE+ LAKP DK R R T +
Sbjct: 376 LKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQAARQASRSTAYE 435
Query: 333 GEY 335
Y
Sbjct: 436 DYY 438
>gi|228008398 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 3 [Homo sapiens]
Length = 527
Score = 268 bits (685), Expect = 1e-71
Identities = 159/381 (41%), Positives = 207/381 (54%), Gaps = 48/381 (12%)
Query: 39 LEKENGQRKYGGPPPG--WDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMM 96
L+ GQRKYGGPPP + P G EIF+GK+PRDLFEDEL+PL EK G I+++R+M
Sbjct: 135 LDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLM 194
Query: 97 MD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTK 155
MD G NRGYAFVTF K A+ A+K NN+EIR+G+ +GVC SV N RLFVG IPK+K
Sbjct: 195 MDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSK 254
Query: 156 KREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLW 215
+E+IL E KVTEG+ DVI+Y DK KNRGF F+EYE H+ AA
Sbjct: 255 TKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA-------------- 300
Query: 216 GHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD 275
VK+L+VRNL + +EE++EK F+ G +ERVKK++D
Sbjct: 301 ---------------------QVKVLFVRNLANTVTEEILEKAFSQF--GKLERVKKLKD 337
Query: 276 YAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRGTMLQGEY 335
YAF+HF R+ AV+AM+ +NGK L+G IE+ AKP D+ R + + M Y
Sbjct: 338 YAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYY 397
Query: 336 TYSLGQVYDPTT--------TYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRAPSV 387
Y + PT Y P +Y + Y + +G +
Sbjct: 398 YYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQ 457
Query: 388 RGAAGVRGLGGRGYLAYTGLG 408
GA G G G RG G G
Sbjct: 458 VGARGRGGRGARGAAPSRGRG 478
>gi|228008295 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 4 [Homo sapiens]
Length = 588
Score = 268 bits (685), Expect = 1e-71
Identities = 159/381 (41%), Positives = 207/381 (54%), Gaps = 48/381 (12%)
Query: 39 LEKENGQRKYGGPPPG--WDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMM 96
L+ GQRKYGGPPP + P G EIF+GK+PRDLFEDEL+PL EK G I+++R+M
Sbjct: 135 LDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLM 194
Query: 97 MD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTK 155
MD G NRGYAFVTF K A+ A+K NN+EIR+G+ +GVC SV N RLFVG IPK+K
Sbjct: 195 MDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSK 254
Query: 156 KREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLW 215
+E+IL E KVTEG+ DVI+Y DK KNRGF F+EYE H+ AA
Sbjct: 255 TKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA-------------- 300
Query: 216 GHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD 275
VK+L+VRNL + +EE++EK F+ G +ERVKK++D
Sbjct: 301 ---------------------QVKVLFVRNLANTVTEEILEKAFSQF--GKLERVKKLKD 337
Query: 276 YAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRGTMLQGEY 335
YAF+HF R+ AV+AM+ +NGK L+G IE+ AKP D+ R + + M Y
Sbjct: 338 YAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYY 397
Query: 336 TYSLGQVYDPTT--------TYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRAPSV 387
Y + PT Y P +Y + Y + +G +
Sbjct: 398 YYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQ 457
Query: 388 RGAAGVRGLGGRGYLAYTGLG 408
GA G G G RG G G
Sbjct: 458 VGARGRGGRGARGAAPSRGRG 478
>gi|34740339 dead end homolog 1 [Homo sapiens]
Length = 353
Score = 167 bits (424), Expect = 2e-41
Identities = 82/203 (40%), Positives = 132/203 (65%), Gaps = 4/203 (1%)
Query: 29 ALQSIILQT--LLEKENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEK 86
AL++ + +T L + NGQRKYGGPPPGW +PP G E+FIG+LP+D++E +LIPL ++
Sbjct: 21 ALEAWVRETGIRLVQVNGQRKYGGPPPGWVGSPPPAGSEVFIGRLPQDVYEHQLIPLFQR 80
Query: 87 IGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRL 146
+G++YE R+MM F+G NRG+A+ +S++ A+ AI L+N+ +R L VC S + C L
Sbjct: 81 VGRLYEFRLMMTFSGLNRGFAYARYSSRRGAQAAIATLHNHPLRPSCPLLVCRSTEKCEL 140
Query: 147 FVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRK 206
V G+P R +L ++ + G+ + + PS A +++ SHRAAAMA++
Sbjct: 141 SVDGLPPNLTRSALLLALQPLGPGLQEARLLPSPGPAPGQ--IALLKFSSHRAAAMAKKA 198
Query: 207 LLPGRIQLWGHGIAVDWAEPEVE 229
L+ G+ L G +AV+W +P+++
Sbjct: 199 LVEGQSHLCGEQVAVEWLKPDLK 221
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 86.3 bits (212), Expect = 7e-17
Identities = 80/284 (28%), Positives = 132/284 (46%), Gaps = 54/284 (19%)
Query: 66 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 125
+FI L + + L GKI ++M D G+ +GYAFV F N+ A AI+++N
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQGS-KGYAFVHFQNQSAADRAIEEMN 158
Query: 126 NYEIRNGRLLGVCASVDNCRLFVGGIPKTKKRE-EILSEMKKVT-------------EGV 171
G+LL C++FVG K RE E+ S+ + T E +
Sbjct: 159 ------GKLL------KGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERL 206
Query: 172 VDVI--------VYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRI--QLWGHGIAV 221
DV V K++GF FV ++SH AA A ++ I QL G A
Sbjct: 207 KDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQ 266
Query: 222 DWAEPEVEVDE--DTMSSVKI-------LYVRNLMLSTSEEMIEKEFNNIKPGAVERVKK 272
E + E+ + + + +I LY++NL + +E + EF++ G++ RVK
Sbjct: 267 KKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLRNEFSSF--GSISRVKV 324
Query: 273 IRD------YAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAK 310
+++ + + FS+ EDA +AM +NG++L P+ + LA+
Sbjct: 325 MQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQ 368
Score = 56.2 bits (134), Expect = 8e-08
Identities = 69/288 (23%), Positives = 125/288 (43%), Gaps = 37/288 (12%)
Query: 56 DAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNK 114
+ A R +++G L D+ ED L +G + +R+ D + GYA+V F
Sbjct: 2 NVAAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQL 61
Query: 115 VEAKNAIKQLNNYEIRNGRLLGVCASVDNCRL--------FVGGIPKT---KKREEILSE 163
+A+ A+ + N++I G+ + + S + L F+ + K+ K E S
Sbjct: 62 ADAQKALDTM-NFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSA 120
Query: 164 MKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMA----RRKLLPGRIQLWGHGI 219
K+ V +D ++G+AFV +++ AA A KLL G G
Sbjct: 121 FGKILSSKV-------MSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFK 173
Query: 220 AVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVK-------K 272
E E+ ++V Y++N +E ++ F+ K G VK K
Sbjct: 174 NRKDREAELRSKASEFTNV---YIKNFGGDMDDERLKDVFS--KYGKTLSVKVMTDSSGK 228
Query: 273 IRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLA-KPVDKDSYVR 319
+ + FV F + E A +A++ +NG+ ++G I V A K V++ + ++
Sbjct: 229 SKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELK 276
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 73.2 bits (178), Expect = 6e-13
Identities = 84/344 (24%), Positives = 150/344 (43%), Gaps = 62/344 (18%)
Query: 66 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 125
+FI L + + L G I +++ D NG+ +GYAFV F + A AI+++N
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS-KGYAFVHFETQEAADKAIEKMN 159
Query: 126 NYEIRNGRLLGVCASVDNCRLFVGGIPKTKKRE-EILSEMKKVT--------EGVVDVIV 176
G LL ++ ++FVG K+RE E+ ++ K+ T E V D +
Sbjct: 160 ------GMLL------NDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESL 207
Query: 177 YP--SAADKT-----------KNRGFAFVEYESHRAAAMARRKL----LPGRIQLWGHGI 219
S KT K++GF FV YE H A A ++ + G+I G
Sbjct: 208 KELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQ 267
Query: 220 AVDWAEPEVEVDEDTMSSVKI-------LYVRNLMLSTSEEMIEKEFNNIKPGAVERVK- 271
+ E++ + + +I LY++NL + +E + KEF+ G++ K
Sbjct: 268 KKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPF--GSITSAKV 325
Query: 272 -----KIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDK------DSYVRY 320
+ + + FV FS+ E+A +A+ +NG+++ P+ V LA+ ++ + Y++
Sbjct: 326 MLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQR 385
Query: 321 TRGTGG-RGTMLQGEYTYSLGQVYDPTTTYL-GAPVFYAPQTYA 362
G + ++ + G + P G P +Y P A
Sbjct: 386 VAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLA 429
Score = 59.7 bits (143), Expect = 7e-09
Identities = 62/271 (22%), Positives = 120/271 (44%), Gaps = 23/271 (8%)
Query: 66 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDF-NGNNRGYAFVTFSNKVEAKNAIKQL 124
+++G L D+ E L G + +R+ D + GYA+V F +A+ A+ +
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 125 NNYEIRNGRLLGVCASVDNCRLFVGGIPKT--KKREEILSE--MKKVTEGVVDVIVYPSA 180
N+++ G+ + + S + L G+ K ++ + + +++
Sbjct: 73 -NFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 181 ADKTKNRGFAFVEYESHRAAAMARRK----LLPGRIQLWGHGIAVDWAEPEVEVDEDTMS 236
D+ ++G+AFV +E+ AA A K LL R G + E E+ +
Sbjct: 132 CDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFT 191
Query: 237 SVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD-------YAFVHFSNREDAVE 289
+V Y++N +E +++ F+ G VK +RD + FV + EDA +
Sbjct: 192 NV---YIKNFGEEVDDESLKELFSQF--GKTLSVKVMRDPNGKSKGFGFVSYEKHEDANK 246
Query: 290 AMKALNGKVLDGSPIEVTLA-KPVDKDSYVR 319
A++ +NGK + G I V A K V++ + ++
Sbjct: 247 AVEEMNGKEISGKIIFVGRAQKKVERQAELK 277
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 73.2 bits (178), Expect = 6e-13
Identities = 84/344 (24%), Positives = 150/344 (43%), Gaps = 62/344 (18%)
Query: 66 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 125
+FI L + + L G I +++ D NG+ +GYAFV F + A AI+++N
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS-KGYAFVHFETQEAADKAIEKMN 159
Query: 126 NYEIRNGRLLGVCASVDNCRLFVGGIPKTKKRE-EILSEMKKVT--------EGVVDVIV 176
G LL ++ ++FVG K+RE E+ ++ K+ T E V D +
Sbjct: 160 ------GMLL------NDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESL 207
Query: 177 YP--SAADKT-----------KNRGFAFVEYESHRAAAMARRKL----LPGRIQLWGHGI 219
S KT K++GF FV YE H A A ++ + G+I G
Sbjct: 208 KELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQ 267
Query: 220 AVDWAEPEVEVDEDTMSSVKI-------LYVRNLMLSTSEEMIEKEFNNIKPGAVERVK- 271
+ E++ + + +I LY++NL + +E + KEF+ G++ K
Sbjct: 268 KKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPF--GSITSAKV 325
Query: 272 -----KIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDK------DSYVRY 320
+ + + FV FS+ E+A +A+ +NG+++ P+ V LA+ ++ + Y++
Sbjct: 326 MLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQR 385
Query: 321 TRGTGG-RGTMLQGEYTYSLGQVYDPTTTYL-GAPVFYAPQTYA 362
G + ++ + G + P G P +Y P A
Sbjct: 386 VAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLA 429
Score = 59.7 bits (143), Expect = 7e-09
Identities = 62/271 (22%), Positives = 120/271 (44%), Gaps = 23/271 (8%)
Query: 66 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDF-NGNNRGYAFVTFSNKVEAKNAIKQL 124
+++G L D+ E L G + +R+ D + GYA+V F +A+ A+ +
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 125 NNYEIRNGRLLGVCASVDNCRLFVGGIPKT--KKREEILSE--MKKVTEGVVDVIVYPSA 180
N+++ G+ + + S + L G+ K ++ + + +++
Sbjct: 73 -NFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 181 ADKTKNRGFAFVEYESHRAAAMARRK----LLPGRIQLWGHGIAVDWAEPEVEVDEDTMS 236
D+ ++G+AFV +E+ AA A K LL R G + E E+ +
Sbjct: 132 CDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFT 191
Query: 237 SVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD-------YAFVHFSNREDAVE 289
+V Y++N +E +++ F+ G VK +RD + FV + EDA +
Sbjct: 192 NV---YIKNFGEEVDDESLKELFSQF--GKTLSVKVMRDPNGKSKGFGFVSYEKHEDANK 246
Query: 290 AMKALNGKVLDGSPIEVTLA-KPVDKDSYVR 319
A++ +NGK + G I V A K V++ + ++
Sbjct: 247 AVEEMNGKEISGKIIFVGRAQKKVERQAELK 277
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 73.2 bits (178), Expect = 6e-13
Identities = 84/344 (24%), Positives = 150/344 (43%), Gaps = 62/344 (18%)
Query: 66 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 125
+FI L + + L G I +++ D NG+ +GYAFV F + A AI+++N
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS-KGYAFVHFETQEAADKAIEKMN 159
Query: 126 NYEIRNGRLLGVCASVDNCRLFVGGIPKTKKRE-EILSEMKKVT--------EGVVDVIV 176
G LL ++ ++FVG K+RE E+ ++ K+ T E V D +
Sbjct: 160 ------GMLL------NDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESL 207
Query: 177 YP--SAADKT-----------KNRGFAFVEYESHRAAAMARRKL----LPGRIQLWGHGI 219
S KT K++GF FV YE H A A ++ + G+I G
Sbjct: 208 KELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQ 267
Query: 220 AVDWAEPEVEVDEDTMSSVKI-------LYVRNLMLSTSEEMIEKEFNNIKPGAVERVK- 271
+ E++ + + +I LY++NL + +E + KEF+ G++ K
Sbjct: 268 KKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPF--GSITSAKV 325
Query: 272 -----KIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDK------DSYVRY 320
+ + + FV FS+ E+A +A+ +NG+++ P+ V LA+ ++ + Y++
Sbjct: 326 MLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQR 385
Query: 321 TRGTGG-RGTMLQGEYTYSLGQVYDPTTTYL-GAPVFYAPQTYA 362
G + ++ + G + P G P +Y P A
Sbjct: 386 VAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLA 429
Score = 59.7 bits (143), Expect = 7e-09
Identities = 62/271 (22%), Positives = 120/271 (44%), Gaps = 23/271 (8%)
Query: 66 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDF-NGNNRGYAFVTFSNKVEAKNAIKQL 124
+++G L D+ E L G + +R+ D + GYA+V F +A+ A+ +
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 125 NNYEIRNGRLLGVCASVDNCRLFVGGIPKT--KKREEILSE--MKKVTEGVVDVIVYPSA 180
N+++ G+ + + S + L G+ K ++ + + +++
Sbjct: 73 -NFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 181 ADKTKNRGFAFVEYESHRAAAMARRK----LLPGRIQLWGHGIAVDWAEPEVEVDEDTMS 236
D+ ++G+AFV +E+ AA A K LL R G + E E+ +
Sbjct: 132 CDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFT 191
Query: 237 SVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD-------YAFVHFSNREDAVE 289
+V Y++N +E +++ F+ G VK +RD + FV + EDA +
Sbjct: 192 NV---YIKNFGEEVDDESLKELFSQF--GKTLSVKVMRDPNGKSKGFGFVSYEKHEDANK 246
Query: 290 AMKALNGKVLDGSPIEVTLA-KPVDKDSYVR 319
A++ +NGK + G I V A K V++ + ++
Sbjct: 247 AVEEMNGKEISGKIIFVGRAQKKVERQAELK 277
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 70.1 bits (170), Expect = 5e-12
Identities = 75/286 (26%), Positives = 119/286 (41%), Gaps = 58/286 (20%)
Query: 66 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 125
IF+ L + + L G I ++ D NG+ +GY FV F A+ AIK++N
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGS-KGYGFVHFETHEAAERAIKKMN 159
Query: 126 NYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSE---------MKKVTEGVVD--- 173
+ NGR ++FVG K+RE L +K E + D
Sbjct: 160 GM-LLNGR-----------KVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERL 207
Query: 174 ----------VIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDW 223
+ V + K++GF FV +E H A A ++ +L G I V
Sbjct: 208 KDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEM--NGKELNGKQIYVGR 265
Query: 224 AEPEVE-------------VDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERV 270
A+ +VE D T V LYV+NL +E + K F+ G +
Sbjct: 266 AQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPF--GTITSA 323
Query: 271 K------KIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAK 310
K + + + FV FS+ E+A +A+ +NG+++ P+ V LA+
Sbjct: 324 KVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQ 369
Score = 68.2 bits (165), Expect = 2e-11
Identities = 67/280 (23%), Positives = 121/280 (43%), Gaps = 19/280 (6%)
Query: 57 AAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDF-NGNNRGYAFVTFSNKV 115
+ P +++G L D+ E L G I +R+ D + YA+V F +
Sbjct: 4 STPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTK 63
Query: 116 EAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVV--- 172
+A++A+ +N +++ G+ + + S + L G+ + S K V
Sbjct: 64 DAEHALDTMN-FDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAF 122
Query: 173 -DVIVYPSAADKTKNRGFAFVEYESHRAAAMARRK----LLPGRIQLWGHGIAVDWAEPE 227
+++ D+ ++G+ FV +E+H AA A +K LL GR G + E E
Sbjct: 123 GNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAE 182
Query: 228 VEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVK-----KIRDYAFVHFS 282
+ +V Y++N +E ++ F P +V K + + FV F
Sbjct: 183 LGARAKEFPNV---YIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFE 239
Query: 283 NREDAVEAMKALNGKVLDGSPIEVTLA-KPVDKDSYVRYT 321
EDA +A+ +NGK L+G I V A K V++ + ++ T
Sbjct: 240 RHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRT 279
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 69.3 bits (168), Expect = 9e-12
Identities = 92/362 (25%), Positives = 147/362 (40%), Gaps = 77/362 (21%)
Query: 66 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 125
IFI L + + L G I +++ D NG+ +GY FV F + A+ AI+++N
Sbjct: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS-KGYGFVHFETQEAAERAIEKMN 159
Query: 126 NYEIRNGRLLGVCASVDNCRLFVGGIPKTKKRE-EILSEMKKVT-------------EGV 171
G LL ++ ++FVG K+RE E+ + K+ T E +
Sbjct: 160 ------GMLL------NDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERL 207
Query: 172 VDVI--------VYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDW 223
D+ V + K++GF FV +E H A A ++ +L G I V
Sbjct: 208 KDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEM--NGKELNGKQIYVGR 265
Query: 224 AEPEVE-------------VDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERV 270
A+ +VE D T LYV+NL +E + KEF+ G +
Sbjct: 266 AQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPF--GTITSA 323
Query: 271 K------KIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGT 324
K + + + FV FS+ E+A +A+ +NG+++ P+ V LA+ ++
Sbjct: 324 KVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEE---------- 373
Query: 325 GGRGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRA 384
R L +Y + V + Y P A PS +F A NRA
Sbjct: 374 --RQAHLTNQYMQRMASVRAVPNPVINP---YQP----APPSGYFMAAIPQTQNRAAYYP 424
Query: 385 PS 386
PS
Sbjct: 425 PS 426
Score = 62.0 bits (149), Expect = 1e-09
Identities = 64/278 (23%), Positives = 119/278 (42%), Gaps = 19/278 (6%)
Query: 57 AAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDF-NGNNRGYAFVTFSNKV 115
+AP +++G L D+ E L G I +R+ D + GYA+V F
Sbjct: 4 SAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPA 63
Query: 116 EAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKT--KKREEILSE--MKKVTEGV 171
+A+ A+ +N +++ G+ + + S + L G+ K ++ + +
Sbjct: 64 DAERALDTMN-FDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAF 122
Query: 172 VDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRK----LLPGRIQLWGHGIAVDWAEPE 227
+++ D+ ++G+ FV +E+ AA A K LL R G + E E
Sbjct: 123 GNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAE 182
Query: 228 VEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVK-----KIRDYAFVHFS 282
+ ++V Y++N +E ++ F P +V K + + FV F
Sbjct: 183 LGARAKEFTNV---YIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFE 239
Query: 283 NREDAVEAMKALNGKVLDGSPIEVTLA-KPVDKDSYVR 319
EDA +A+ +NGK L+G I V A K V++ + ++
Sbjct: 240 RHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELK 277
>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
Length = 382
Score = 67.4 bits (163), Expect = 4e-11
Identities = 74/278 (26%), Positives = 124/278 (44%), Gaps = 41/278 (14%)
Query: 66 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAI---- 121
IFI L + + L L G I +++ D NG+ +GYA+V F + A AI
Sbjct: 108 IFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGS-KGYAYVHFDSLAAANRAIWHMN 166
Query: 122 -KQLNNYEIRNGRLLGVCASVDNCR---------LFVGGIPKTKKREEILSEMKKVTEGV 171
+LNN ++ GR R +FV I E+ L E+
Sbjct: 167 GVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEK-LKELFCEYGPT 225
Query: 172 VDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVE-- 229
V V A+ K+K GF FV YE+H AA A L I G + V A+ ++E
Sbjct: 226 ESVKVIRDASGKSK--GFGFVRYETHEAAQKAVLDLHGKSID--GKVLYVGRAQKKIERL 281
Query: 230 -----------VDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD--- 275
+ E + +Y++NL + ++E +++EF++ G++ R K + +
Sbjct: 282 AELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSF--GSISRAKVMMEVGQ 339
Query: 276 ---YAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAK 310
+ V FS+ E+A +A+ +NG+++ P+ VTL +
Sbjct: 340 GKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVTLGQ 377
Score = 34.3 bits (77), Expect = 0.33
Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 6/80 (7%)
Query: 241 LYVRNLMLSTSEEMIEKEFNNIKPGAVERV------KKIRDYAFVHFSNREDAVEAMKAL 294
LYV +L +E+M+ K+F P R+ + Y +V+F DA A+ +
Sbjct: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
Query: 295 NGKVLDGSPIEVTLAKPVDK 314
N +++G P + ++P D+
Sbjct: 80 NFDLINGKPFRLMWSQPDDR 99
Score = 33.9 bits (76), Expect = 0.43
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 9/78 (11%)
Query: 59 PPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAK 118
PP G I+I L + +++L G I ++MM+ G +G+ V FS+ EA
Sbjct: 299 PP--GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEV-GQGKGFGVVCFSSFEEAT 355
Query: 119 NAIKQLNNYEIRNGRLLG 136
A+ ++ NGR++G
Sbjct: 356 KAVDEM------NGRIVG 367
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 64.3 bits (155), Expect = 3e-10
Identities = 66/292 (22%), Positives = 128/292 (43%), Gaps = 23/292 (7%)
Query: 52 PPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTF 111
P G D+ + LP + +DEL + E +I ++ +G ++G A++ F
Sbjct: 381 PKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEI----RLVSKDGKSKGIAYIEF 436
Query: 112 SNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRL--FVGGIPKTKKREE---ILSEMK- 165
+ +A+ ++ EI +GR + + + + + + GG T E +LS +
Sbjct: 437 KTEADAEKTFEEKQGTEI-DGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSY 495
Query: 166 KVTEGVVDVIVYPSAADKT------KNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGI 219
TE + + + K K++G+AF+E+ S A A I+ G I
Sbjct: 496 SATEETLQEVFEKATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIE--GRAI 553
Query: 220 AVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKI---RDY 276
++ P + + S K L+V+ L T+EE +++ F+ + ++ + +
Sbjct: 554 RLELQGPRGSPNARSQPS-KTLFVKGLSEDTTEETLKESFDGSVRARIVTDRETGSSKGF 612
Query: 277 AFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRG 328
FV F++ EDA A +A+ +DG+ + + AKP + + G GG G
Sbjct: 613 GFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGRGGFG 664
>gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo
sapiens]
Length = 485
Score = 63.5 bits (153), Expect = 5e-10
Identities = 55/180 (30%), Positives = 88/180 (48%), Gaps = 15/180 (8%)
Query: 36 QTLLEKENGQRKYGGP-PPGW--DAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYE 92
Q LL+ GP PPG D ++F+G++PR L E +L PL E+ G+IYE
Sbjct: 14 QQLLQPRPSPVGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYE 73
Query: 93 MRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNG--RLLGVCASVDNCR---- 145
+ ++ D + G ++G AF+T+ + A A L+ + G R + V + R
Sbjct: 74 LTVLKDPYTGMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRD 133
Query: 146 --LFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMA 203
LFVG + K + E++L + GV+D D + ++G AFV++ SH A A
Sbjct: 134 RKLFVGMLNKQQSEEDVLRLFQPF--GVIDECTVLRGPDGS-SKGCAFVKFSSHTEAQAA 190
Score = 45.1 bits (105), Expect = 2e-04
Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 3/87 (3%)
Query: 51 PPPGWDAAPPE--RGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGN-NRGYA 107
PPP E GC +FI LP++ + EL + G I ++ MD N ++ +
Sbjct: 385 PPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFG 444
Query: 108 FVTFSNKVEAKNAIKQLNNYEIRNGRL 134
FV+F N A+ AI+ +N ++I RL
Sbjct: 445 FVSFDNPASAQAAIQAMNGFQIGMKRL 471
Score = 41.2 bits (95), Expect = 0.003
Identities = 22/71 (30%), Positives = 41/71 (57%)
Query: 62 RGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAI 121
R ++F+G L + E++++ L + G I E ++ +G+++G AFV FS+ EA+ AI
Sbjct: 132 RDRKLFVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAI 191
Query: 122 KQLNNYEIRNG 132
L+ + G
Sbjct: 192 HALHGSQTMPG 202
Score = 33.9 bits (76), Expect = 0.43
Identities = 69/290 (23%), Positives = 119/290 (41%), Gaps = 52/290 (17%)
Query: 141 VDNCRLFVGGIPK---TKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESH 197
+D +LFVG IP+ K + + + ++ E V Y ++G AF+ Y +
Sbjct: 42 LDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGM-----HKGCAFLTYCAR 96
Query: 198 RAA-----AMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSE 252
+A A+ +K LPG + I V A+ E D + L+V L SE
Sbjct: 97 DSAIKAQTALHEQKTLPGMAR----PIQVKPADSESRGGRD-----RKLFVGMLNKQQSE 147
Query: 253 EMIEKEFNNIKPGAVERVKKIRD-------YAFVHFSNREDAVEAMKALNG-KVLDGSPI 304
E + + F G ++ +R AFV FS+ +A A+ AL+G + + G+
Sbjct: 148 EDVLRLFQPF--GVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHALHGSQTMPGASS 205
Query: 305 EVTLA-KPVDKDSYVRYTRGTGGRGTMLQGEYT--------YSLGQVYDPTT------TY 349
+ + DK+ +R + G+ +L T Y+ + TT +Y
Sbjct: 206 SLVVKFADTDKERTLRRMQQMVGQLGILTPSLTLPFSPYSAYAQALMQQQTTVLSTSGSY 265
Query: 350 LGAPVFYAP---QTYAAIPSLHFPATKGHLSNRAIIRAPSVRGAAGVRGL 396
L V ++P Q A+ PAT ++ + + +P + G V GL
Sbjct: 266 LSPGVAFSPCHIQQIGAVSLNGLPATP--IAPASGLHSPPLLGTTAVPGL 313
>gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo
sapiens]
Length = 448
Score = 60.5 bits (145), Expect = 4e-09
Identities = 46/147 (31%), Positives = 76/147 (51%), Gaps = 11/147 (7%)
Query: 65 EIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQ 123
++FIG++PR+L E +L PL E+ GKIYE+ ++ D F G ++G AF+T+ + A A
Sbjct: 55 KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114
Query: 124 LNNYEIRNG--RLLGVCASVDNCR-----LFVGGIPKTKKREEILSEMKKVTEGVVDVIV 176
L+ + G R + V + R LFVG + K + +++ + G ++
Sbjct: 115 LHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLNKQQSEDDVRRLFEAF--GNIEECT 172
Query: 177 YPSAADKTKNRGFAFVEYESHRAAAMA 203
D ++G AFV+Y SH A A
Sbjct: 173 ILRGPD-GNSKGCAFVKYSSHAEAQAA 198
Score = 43.9 bits (102), Expect = 4e-04
Identities = 23/68 (33%), Positives = 39/68 (57%)
Query: 65 EIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQL 124
++F+G L + ED++ L E G I E ++ +GN++G AFV +S+ EA+ AI L
Sbjct: 143 KLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINAL 202
Query: 125 NNYEIRNG 132
+ + G
Sbjct: 203 HGSQTMPG 210
Score = 30.4 bits (67), Expect = 4.8
Identities = 43/168 (25%), Positives = 72/168 (42%), Gaps = 28/168 (16%)
Query: 142 DNCRLFVGGIPKT---KKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHR 198
D +LF+G IP+ K + + E K+ E V + ++G AF+ Y
Sbjct: 52 DAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGM-----HKGCAFLTYCERE 106
Query: 199 AA-----AMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEE 253
+A A+ +K LPG I V A+ E ++ + L+V L SE+
Sbjct: 107 SALKAQSALHEQKTLPGM----NRPIQVKPADSESRGED------RKLFVGMLNKQQSED 156
Query: 254 MIEK---EFNNIKPGAVERVK--KIRDYAFVHFSNREDAVEAMKALNG 296
+ + F NI+ + R + AFV +S+ +A A+ AL+G
Sbjct: 157 DVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHG 204
>gi|51948366 ribonucleoprotein, PTB-binding 2 [Homo sapiens]
Length = 678
Score = 60.1 bits (144), Expect = 6e-09
Identities = 66/251 (26%), Positives = 108/251 (43%), Gaps = 15/251 (5%)
Query: 65 EIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQL 124
+I + LP+D E+ L K Y+++ + N+ AFVT N +A+NAI+
Sbjct: 70 KILVKNLPQDSNCQEVHDLL----KDYDLKYC--YVDRNKRTAFVTLLNGEQAQNAIQMF 123
Query: 125 NNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKT 184
+ Y R G+ L V + L + +P + EE ++ +VY +
Sbjct: 124 HQYSFR-GKDLIVQLQPTDALLCITNVPISFTSEEFEELVRAYGNIERCFLVYSEVTGHS 182
Query: 185 KNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVR 244
K G+ FVEY AA AR +LL GR QL + W + + E S +
Sbjct: 183 K--GYGFVEYMKKDFAAKARLELL-GR-QLGASALFAQWMDVNLLASELIHSKCLCIDKL 238
Query: 245 NLMLSTSEEMIEKEFNNIKPG----AVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLD 300
SEE+++ + KP A + + +A V +S E A E +A +G +
Sbjct: 239 PSDYRDSEELLQIFSSVHKPVFCQLAQDEGSYVGGFAVVEYSTAEQAEEVQQAADGMTIK 298
Query: 301 GSPIEVTLAKP 311
GS ++V+ P
Sbjct: 299 GSKVQVSFCAP 309
>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
Length = 375
Score = 58.2 bits (139), Expect = 2e-08
Identities = 64/296 (21%), Positives = 121/296 (40%), Gaps = 38/296 (12%)
Query: 66 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 125
+++G L RD+ E ++ L +IG +M+MD GN+ Y FV F A A+ +N
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
Query: 126 NYEIRNGRLLGVCASVDNCR---------LFVGGIPKTKKREEILSEMKKVTEGVVDVIV 176
+I + A+ + + +FVG + E+I + +V
Sbjct: 68 GRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVV 127
Query: 177 YPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMS 236
A K+K G+ FV + + A A +++ G L G I +WA + + T
Sbjct: 128 KDMATGKSK--GYGFVSFFNKWDAENAIQQM--GGQWLGGRQIRTNWATRKPPAPKSTYE 183
Query: 237 SVK-----------------ILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRDYAFV 279
S +Y + +E+++ + F+ RV + Y+FV
Sbjct: 184 SNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFV 243
Query: 280 HFSNREDAVEAMKALNGKVLDGSPIE-------VTLAKPVDKDSYVRYTRGTGGRG 328
F++ E A A+ ++NG ++G ++ + + PV + + + Y + G G
Sbjct: 244 RFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQIGYPQPYGQWG 299
>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
Length = 386
Score = 58.2 bits (139), Expect = 2e-08
Identities = 65/307 (21%), Positives = 122/307 (39%), Gaps = 49/307 (15%)
Query: 66 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 125
+++G L RD+ E ++ L +IG +M+MD GN+ Y FV F A A+ +N
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
Query: 126 NYEIR--------------------NGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMK 165
+I + ++ S D+ +FVG + E+I +
Sbjct: 68 GRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFA 127
Query: 166 KVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAE 225
+V A K+K G+ FV + + A A +++ G L G I +WA
Sbjct: 128 PFGRISDARVVKDMATGKSK--GYGFVSFFNKWDAENAIQQM--GGQWLGGRQIRTNWAT 183
Query: 226 PEVEVDEDTMSSVK-----------------ILYVRNLMLSTSEEMIEKEFNNIKPGAVE 268
+ + T S +Y + +E+++ + F+
Sbjct: 184 RKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEI 243
Query: 269 RVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIE-------VTLAKPVDKDSYVRYT 321
RV + Y+FV F++ E A A+ ++NG ++G ++ + + PV + + + Y
Sbjct: 244 RVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQIGYP 303
Query: 322 RGTGGRG 328
+ G G
Sbjct: 304 QPYGQWG 310
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,177,650
Number of Sequences: 37866
Number of extensions: 1186370
Number of successful extensions: 4362
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 169
Number of HSP's successfully gapped in prelim test: 97
Number of HSP's that attempted gapping in prelim test: 3496
Number of HSP's gapped (non-prelim): 667
length of query: 594
length of database: 18,247,518
effective HSP length: 108
effective length of query: 486
effective length of database: 14,157,990
effective search space: 6880783140
effective search space used: 6880783140
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.