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Search of human proteins with 20357575
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20357575 apobec-1 complementation factor isoform 2 [Homo
sapiens]
(594 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20357575 apobec-1 complementation factor isoform 2 [Homo sapi... 1197 0.0
gi|20357572 apobec-1 complementation factor isoform 1 [Homo sapi... 1174 0.0
gi|20357578 apobec-1 complementation factor isoform 3 [Homo sapi... 1114 0.0
gi|148833513 RNA binding motif protein 47 isoform a [Homo sapiens] 519 e-147
gi|148833511 RNA binding motif protein 47 isoform b [Homo sapiens] 486 e-137
gi|21450675 RNA binding motif protein 46 [Homo sapiens] 464 e-131
gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4... 335 7e-92
gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2 [... 335 7e-92
gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting ... 334 1e-91
gi|228008396 synaptotagmin binding, cytoplasmic RNA interacting ... 334 1e-91
gi|228008293 synaptotagmin binding, cytoplasmic RNA interacting ... 334 1e-91
gi|228008291 synaptotagmin binding, cytoplasmic RNA interacting ... 334 1e-91
gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3... 330 3e-90
gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1... 330 3e-90
gi|228008398 synaptotagmin binding, cytoplasmic RNA interacting ... 285 1e-76
gi|228008295 synaptotagmin binding, cytoplasmic RNA interacting ... 285 1e-76
gi|34740339 dead end homolog 1 [Homo sapiens] 183 4e-46
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 86 7e-17
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 73 6e-13
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 73 6e-13
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 73 6e-13
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 70 5e-12
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 69 9e-12
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens] 67 4e-11
gi|55956788 nucleolin [Homo sapiens] 64 3e-10
gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo sa... 64 4e-10
gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo s... 60 4e-09
gi|51948366 ribonucleoprotein, PTB-binding 2 [Homo sapiens] 60 6e-09
gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 58 2e-08
gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 58 2e-08
>gi|20357575 apobec-1 complementation factor isoform 2 [Homo
sapiens]
Length = 594
Score = 1197 bits (3098), Expect = 0.0
Identities = 594/594 (100%), Positives = 594/594 (100%)
Query: 1 MESNHKSGDGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFI 60
MESNHKSGDGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFI
Sbjct: 1 MESNHKSGDGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFI 60
Query: 61 GKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYE 120
GKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYE
Sbjct: 61 GKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYE 120
Query: 121 IRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRG 180
IRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRG
Sbjct: 121 IRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRG 180
Query: 181 FAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLML 240
FAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLML
Sbjct: 181 FAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLML 240
Query: 241 STSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTL 300
STSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTL
Sbjct: 241 STSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTL 300
Query: 301 AKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLH 360
AKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLH
Sbjct: 301 AKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLH 360
Query: 361 FPATKGHLSNRAIIRAPSVREIYMNVPVGAAGVRGLGGRGYLAYTGLGRGYQVKGDKRED 420
FPATKGHLSNRAIIRAPSVREIYMNVPVGAAGVRGLGGRGYLAYTGLGRGYQVKGDKRED
Sbjct: 361 FPATKGHLSNRAIIRAPSVREIYMNVPVGAAGVRGLGGRGYLAYTGLGRGYQVKGDKRED 420
Query: 421 KLYDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFL 480
KLYDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFL
Sbjct: 421 KLYDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFL 480
Query: 481 YKITIPALASQNPAIHPFTPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAA 540
YKITIPALASQNPAIHPFTPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAA
Sbjct: 481 YKITIPALASQNPAIHPFTPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAA 540
Query: 541 TAFPGYAVPNATAPVSAAQLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF 594
TAFPGYAVPNATAPVSAAQLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF
Sbjct: 541 TAFPGYAVPNATAPVSAAQLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF 594
>gi|20357572 apobec-1 complementation factor isoform 1 [Homo
sapiens]
Length = 586
Score = 1174 bits (3037), Expect = 0.0
Identities = 586/594 (98%), Positives = 586/594 (98%), Gaps = 8/594 (1%)
Query: 1 MESNHKSGDGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFI 60
MESNHKSGDGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFI
Sbjct: 1 MESNHKSGDGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFI 60
Query: 61 GKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYE 120
GKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYE
Sbjct: 61 GKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYE 120
Query: 121 IRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRG 180
IRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRG
Sbjct: 121 IRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRG 180
Query: 181 FAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLML 240
FAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLML
Sbjct: 181 FAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLML 240
Query: 241 STSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTL 300
STSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTL
Sbjct: 241 STSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTL 300
Query: 301 AKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLH 360
AKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLH
Sbjct: 301 AKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLH 360
Query: 361 FPATKGHLSNRAIIRAPSVREIYMNVPVGAAGVRGLGGRGYLAYTGLGRGYQVKGDKRED 420
FPATKGHLSNRAIIRAPSVR GAAGVRGLGGRGYLAYTGLGRGYQVKGDKRED
Sbjct: 361 FPATKGHLSNRAIIRAPSVR--------GAAGVRGLGGRGYLAYTGLGRGYQVKGDKRED 412
Query: 421 KLYDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFL 480
KLYDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFL
Sbjct: 413 KLYDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFL 472
Query: 481 YKITIPALASQNPAIHPFTPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAA 540
YKITIPALASQNPAIHPFTPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAA
Sbjct: 473 YKITIPALASQNPAIHPFTPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAA 532
Query: 541 TAFPGYAVPNATAPVSAAQLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF 594
TAFPGYAVPNATAPVSAAQLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF
Sbjct: 533 TAFPGYAVPNATAPVSAAQLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF 586
>gi|20357578 apobec-1 complementation factor isoform 3 [Homo
sapiens]
Length = 594
Score = 1114 bits (2881), Expect = 0.0
Identities = 557/576 (96%), Positives = 563/576 (97%), Gaps = 10/576 (1%)
Query: 19 ALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEK 78
AL++++ +T L +ENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEK
Sbjct: 29 ALQSIILQT--LLEKENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEK 86
Query: 79 IGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRL 138
IGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRL
Sbjct: 87 IGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRL 146
Query: 139 FVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRK 198
FVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRK
Sbjct: 147 FVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRK 206
Query: 199 LLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGA 258
LLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGA
Sbjct: 207 LLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGA 266
Query: 259 VERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGG 318
VERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGG
Sbjct: 267 VERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGG 326
Query: 319 RGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRAPS 378
RGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRAPS
Sbjct: 327 RGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRAPS 386
Query: 379 VREIYMNVPVGAAGVRGLGGRGYLAYTGLGRGYQVKGDKREDKLYDILPGMELTPMNPVT 438
VR GAAGVRGLGGRGYLAYTGLGRGYQVKGDKREDKLYDILPGMELTPMNPVT
Sbjct: 387 VR--------GAAGVRGLGGRGYLAYTGLGRGYQVKGDKREDKLYDILPGMELTPMNPVT 438
Query: 439 LKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKITIPALASQNPAIHPF 498
LKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKITIPALASQNPAIHPF
Sbjct: 439 LKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKITIPALASQNPAIHPF 498
Query: 499 TPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAATAFPGYAVPNATAPVSAA 558
TPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAATAFPGYAVPNATAPVSAA
Sbjct: 499 TPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAATAFPGYAVPNATAPVSAA 558
Query: 559 QLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF 594
QLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF
Sbjct: 559 QLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF 594
>gi|148833513 RNA binding motif protein 47 isoform a [Homo sapiens]
Length = 593
Score = 519 bits (1336), Expect = e-147
Identities = 287/588 (48%), Positives = 361/588 (61%), Gaps = 79/588 (13%)
Query: 3 SNHKSGDGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFIGK 62
S+ K +G++G EAAL AL++RTGYS+VQENGQRKYGGPPPGW+ P+RGCE+F+GK
Sbjct: 18 SSAKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPGWEGPHPQRGCEVFVGK 77
Query: 63 LPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIR 122
+PRD++EDEL+P+ E +G+IYE+R+MMDF+G NRGYAFV + +K EAK A+++LNNYEIR
Sbjct: 78 IPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELNNYEIR 137
Query: 123 NGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFA 182
GRLLGVC SVDNCRLF+GGIPK KKREEIL E+ KVTEGV+DVIVY SAADK KNRGFA
Sbjct: 138 PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFA 197
Query: 183 FVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLST 242
FVEYESHRAAAMARRKL+PGRIQLWGH IAVDWAEPE++VDED M +VKILYVRNLM+ T
Sbjct: 198 FVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIET 257
Query: 243 SEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAK 302
+E+ I+K F PG VERVKKIRDYAFVHF++REDAV AM LNG L+GS +EVTLAK
Sbjct: 258 TEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAK 317
Query: 303 PVDKDSYVRY---TRGTGGRGTMLQGEYTYSLGQVYDP-TTTYLGAPVFYAPQTYAAI-- 356
PVDK+ Y RY RG G Q Y YS DP T Y G P Y A+
Sbjct: 318 PVDKEQYSRYQKAARGGGAAEAAQQPSYVYSC----DPYTLAYYGYP-------YNALIG 366
Query: 357 PSLHFPATKGHLSNRAIIRAPSVREIYMNVPVGAAGVRGLGGRG-YLAYTGLGRG----Y 411
P+ + G + R GAAG R G RG YL GRG Y
Sbjct: 367 PNRDYFVKAGSIRGRG---------------RGAAGNRAPGPRGSYLGGYSAGRGIYSRY 411
Query: 412 QVKGDKREDKLYDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAI 471
K+++K Y+++P +E+ +NPV +KP
Sbjct: 412 HEGKGKQQEKGYELVPNLEIPTVNPVAIKPG----------------------------- 442
Query: 472 GQDQRQLFLYKITIPALASQNPAIHPFTPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDG 531
+ IPA+ +Q PK+ +++ K + E+ + + + D
Sbjct: 443 ----------TVAIPAIGAQYSMFPAAPAPKM---IEDGKIHTVEHMISPIAVQPDPASA 489
Query: 532 TMATAAAAATAFPGYAVPNATAPVSAAQLKQAVTLGQDLAAYTTYEVY 579
A AAAAA A + P + T+ ++ T +Y
Sbjct: 490 AAAAAAAAAAAAAVIPTVSTPPPFQGRPITPVYTVAPNVQRIPTAGIY 537
>gi|148833511 RNA binding motif protein 47 isoform b [Homo sapiens]
Length = 524
Score = 486 bits (1252), Expect = e-137
Identities = 238/347 (68%), Positives = 280/347 (80%), Gaps = 8/347 (2%)
Query: 3 SNHKSGDGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFIGK 62
S+ K +G++G EAAL AL++RTGYS+VQENGQRKYGGPPPGW+ P+RGCE+F+GK
Sbjct: 18 SSAKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPGWEGPHPQRGCEVFVGK 77
Query: 63 LPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIR 122
+PRD++EDEL+P+ E +G+IYE+R+MMDF+G NRGYAFV + +K EAK A+++LNNYEIR
Sbjct: 78 IPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELNNYEIR 137
Query: 123 NGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFA 182
GRLLGVC SVDNCRLF+GGIPK KKREEIL E+ KVTEGV+DVIVY SAADK KNRGFA
Sbjct: 138 PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFA 197
Query: 183 FVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLST 242
FVEYESHRAAAMARRKL+PGRIQLWGH IAVDWAEPE++VDED M +VKILYVRNLM+ T
Sbjct: 198 FVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIET 257
Query: 243 SEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAK 302
+E+ I+K F PG VERVKKIRDYAFVHF++REDAV AM LNG L+GS +EVTLAK
Sbjct: 258 TEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAK 317
Query: 303 PVDKDSYVRY---TRGTGGRGTMLQGEYTYSLGQVYDP-TTTYLGAP 345
PVDK+ Y RY RG G Q Y YS DP T Y G P
Sbjct: 318 PVDKEQYSRYQKAARGGGAAEAAQQPSYVYSC----DPYTLAYYGYP 360
>gi|21450675 RNA binding motif protein 46 [Homo sapiens]
Length = 533
Score = 464 bits (1195), Expect = e-131
Identities = 216/297 (72%), Positives = 258/297 (86%)
Query: 12 SGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDE 71
+G Q EAAL AL+++TGY++VQENGQRK+GGPPPGW+ PP RGCE+F+GK+PRD++EDE
Sbjct: 17 TGIQNEAALLALMEKTGYNMVQENGQRKFGGPPPGWEGPPPPRGCEVFVGKIPRDMYEDE 76
Query: 72 LIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCA 131
L+P+ E+ GKIYE R+MM+F+G NRGYAFV ++ K EA+ AI+ LNNYEIR G+ +GVC
Sbjct: 77 LVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCV 136
Query: 132 SVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRA 191
S+DNCRLF+G IPK KK+EEIL EMKKVTEGVVDVIVYPSA DKTKNRGFAFVEYESHRA
Sbjct: 137 SLDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRA 196
Query: 192 AAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEF 251
AAMARRKL+PG QLWGH I VDWA+PE EVDE+TM VK+LYVRNLM+ST+EE I+ EF
Sbjct: 197 AAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEF 256
Query: 252 NNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDS 308
N KPGAVERVKK+RDYAFVHF NREDAV AM +NGK +DG+ IEVTLAKPV+K++
Sbjct: 257 NKFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKEN 313
Score = 75.5 bits (184), Expect = 1e-13
Identities = 39/97 (40%), Positives = 56/97 (57%), Gaps = 2/97 (2%)
Query: 423 YDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYK 482
Y PG +LTP++ +LK A L+ C KNNW P Y L+S QD + L +YK
Sbjct: 370 YPFYPGTKLTPISMYSLKSNHFNSAVMHLDYYCNKNNWAPPEYYLYSTTSQDGKVLLVYK 429
Query: 483 ITIPALASQNPAIHPFTPPKLSAFVDEAKTYAAEYTL 519
I IPA+A+ + + F P KL +++AK AA++TL
Sbjct: 430 IVIPAIANGSQSY--FMPDKLCTTLEDAKELAAQFTL 464
>gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4
[Homo sapiens]
Length = 532
Score = 335 bits (859), Expect = 7e-92
Identities = 165/314 (52%), Positives = 222/314 (70%), Gaps = 5/314 (1%)
Query: 17 EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFIGKLPRDLFEDELIP 74
EA ++AL++RTGY+L GQRKYGGPPP + P G E+F+GK+PRDL+EDEL+P
Sbjct: 23 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVP 82
Query: 75 LCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASV 133
L EK G I+++R+MMD +G NRGYAF+TF K A+ A+K ++YEIR G+ LGVC SV
Sbjct: 83 LFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISV 142
Query: 134 DNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAA 193
N RLFVG IPK K +E IL E KVTEG+VDVI+Y DK KNRGF F+EYE H++AA
Sbjct: 143 ANNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAA 202
Query: 194 MARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNN 253
ARR+L+ G++++WG+ + V+WA+P E D + M+ VK+L+VRNL + +EE++EK F+
Sbjct: 203 QARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSE 262
Query: 254 IKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYT 313
G +ERVKK++DYAFVHF +R AV+AM +NGK ++G IE+ LAKP DK R
Sbjct: 263 F--GKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQA 320
Query: 314 RGTGGRGTMLQGEY 327
R T + Y
Sbjct: 321 ARQASRSTAYEDYY 334
>gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2
[Homo sapiens]
Length = 633
Score = 335 bits (859), Expect = 7e-92
Identities = 165/314 (52%), Positives = 222/314 (70%), Gaps = 5/314 (1%)
Query: 17 EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFIGKLPRDLFEDELIP 74
EA ++AL++RTGY+L GQRKYGGPPP + P G E+F+GK+PRDL+EDEL+P
Sbjct: 124 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVP 183
Query: 75 LCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASV 133
L EK G I+++R+MMD +G NRGYAF+TF K A+ A+K ++YEIR G+ LGVC SV
Sbjct: 184 LFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISV 243
Query: 134 DNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAA 193
N RLFVG IPK K +E IL E KVTEG+VDVI+Y DK KNRGF F+EYE H++AA
Sbjct: 244 ANNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAA 303
Query: 194 MARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNN 253
ARR+L+ G++++WG+ + V+WA+P E D + M+ VK+L+VRNL + +EE++EK F+
Sbjct: 304 QARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSE 363
Query: 254 IKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYT 313
G +ERVKK++DYAFVHF +R AV+AM +NGK ++G IE+ LAKP DK R
Sbjct: 364 F--GKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQA 421
Query: 314 RGTGGRGTMLQGEY 327
R T + Y
Sbjct: 422 ARQASRSTAYEDYY 435
>gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 6 [Homo sapiens]
Length = 562
Score = 334 bits (857), Expect = 1e-91
Identities = 185/417 (44%), Positives = 253/417 (60%), Gaps = 24/417 (5%)
Query: 6 KSGDGLSGTQK---EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFI 60
K G ++ + K EA ++AL++RTGY+L GQRKYGGPPP + P G EIF+
Sbjct: 107 KQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFV 166
Query: 61 GKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNY 119
GK+PRDLFEDEL+PL EK G I+++R+MMD G NRGYAFVTF K A+ A+K NN+
Sbjct: 167 GKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNH 226
Query: 120 EIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNR 179
EIR+G+ +GVC SV N RLFVG IPK+K +E+IL E KVTEG+ DVI+Y DK KNR
Sbjct: 227 EIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNR 286
Query: 180 GFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLM 239
GF F+EYE H+ AA ARR+L+ G++++WG+ V+WA+P + D + M+ VK+L+VRNL
Sbjct: 287 GFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLA 346
Query: 240 LSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVT 299
+ +EE++EK F+ G +ERVKK++DYAF+HF R+ AV+AM+ +NGK L+G IE+
Sbjct: 347 NTVTEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIV 404
Query: 300 LAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTT--------TYLGAPVFYAPQ 351
AKP D+ R + + M Y Y + PT Y P +Y +
Sbjct: 405 FAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYE 464
Query: 352 TYAAIPSLHFPATKGHLSNRAIIRAPSVREIYMNVPVGAAGVRGLGGRGYLAYTGLG 408
Y + +G + Y + VGA G G G RG G G
Sbjct: 465 DYYDYYGYDYHNYRGGYEDPYY--------GYEDFQVGARGRGGRGARGAAPSRGRG 513
>gi|228008396 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 2 [Homo sapiens]
Length = 464
Score = 334 bits (857), Expect = 1e-91
Identities = 185/417 (44%), Positives = 253/417 (60%), Gaps = 24/417 (5%)
Query: 6 KSGDGLSGTQK---EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFI 60
K G ++ + K EA ++AL++RTGY+L GQRKYGGPPP + P G EIF+
Sbjct: 9 KQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFV 68
Query: 61 GKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNY 119
GK+PRDLFEDEL+PL EK G I+++R+MMD G NRGYAFVTF K A+ A+K NN+
Sbjct: 69 GKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNH 128
Query: 120 EIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNR 179
EIR+G+ +GVC SV N RLFVG IPK+K +E+IL E KVTEG+ DVI+Y DK KNR
Sbjct: 129 EIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNR 188
Query: 180 GFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLM 239
GF F+EYE H+ AA ARR+L+ G++++WG+ V+WA+P + D + M+ VK+L+VRNL
Sbjct: 189 GFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLA 248
Query: 240 LSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVT 299
+ +EE++EK F+ G +ERVKK++DYAF+HF R+ AV+AM+ +NGK L+G IE+
Sbjct: 249 NTVTEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIV 306
Query: 300 LAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTT--------TYLGAPVFYAPQ 351
AKP D+ R + + M Y Y + PT Y P +Y +
Sbjct: 307 FAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYE 366
Query: 352 TYAAIPSLHFPATKGHLSNRAIIRAPSVREIYMNVPVGAAGVRGLGGRGYLAYTGLG 408
Y + +G + Y + VGA G G G RG G G
Sbjct: 367 DYYDYYGYDYHNYRGGYEDPYY--------GYEDFQVGARGRGGRGARGAAPSRGRG 415
>gi|228008293 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 5 [Homo sapiens]
Length = 561
Score = 334 bits (857), Expect = 1e-91
Identities = 185/417 (44%), Positives = 253/417 (60%), Gaps = 24/417 (5%)
Query: 6 KSGDGLSGTQK---EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFI 60
K G ++ + K EA ++AL++RTGY+L GQRKYGGPPP + P G EIF+
Sbjct: 107 KQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFV 166
Query: 61 GKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNY 119
GK+PRDLFEDEL+PL EK G I+++R+MMD G NRGYAFVTF K A+ A+K NN+
Sbjct: 167 GKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNH 226
Query: 120 EIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNR 179
EIR+G+ +GVC SV N RLFVG IPK+K +E+IL E KVTEG+ DVI+Y DK KNR
Sbjct: 227 EIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNR 286
Query: 180 GFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLM 239
GF F+EYE H+ AA ARR+L+ G++++WG+ V+WA+P + D + M+ VK+L+VRNL
Sbjct: 287 GFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLA 346
Query: 240 LSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVT 299
+ +EE++EK F+ G +ERVKK++DYAF+HF R+ AV+AM+ +NGK L+G IE+
Sbjct: 347 NTVTEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIV 404
Query: 300 LAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTT--------TYLGAPVFYAPQ 351
AKP D+ R + + M Y Y + PT Y P +Y +
Sbjct: 405 FAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYE 464
Query: 352 TYAAIPSLHFPATKGHLSNRAIIRAPSVREIYMNVPVGAAGVRGLGGRGYLAYTGLG 408
Y + +G + Y + VGA G G G RG G G
Sbjct: 465 DYYDYYGYDYHNYRGGYEDPYY--------GYEDFQVGARGRGGRGARGAAPSRGRG 513
>gi|228008291 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 1 [Homo sapiens]
Length = 623
Score = 334 bits (857), Expect = 1e-91
Identities = 185/417 (44%), Positives = 253/417 (60%), Gaps = 24/417 (5%)
Query: 6 KSGDGLSGTQK---EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFI 60
K G ++ + K EA ++AL++RTGY+L GQRKYGGPPP + P G EIF+
Sbjct: 107 KQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFV 166
Query: 61 GKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNY 119
GK+PRDLFEDEL+PL EK G I+++R+MMD G NRGYAFVTF K A+ A+K NN+
Sbjct: 167 GKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNH 226
Query: 120 EIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNR 179
EIR+G+ +GVC SV N RLFVG IPK+K +E+IL E KVTEG+ DVI+Y DK KNR
Sbjct: 227 EIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNR 286
Query: 180 GFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLM 239
GF F+EYE H+ AA ARR+L+ G++++WG+ V+WA+P + D + M+ VK+L+VRNL
Sbjct: 287 GFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLA 346
Query: 240 LSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVT 299
+ +EE++EK F+ G +ERVKK++DYAF+HF R+ AV+AM+ +NGK L+G IE+
Sbjct: 347 NTVTEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIV 404
Query: 300 LAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTT--------TYLGAPVFYAPQ 351
AKP D+ R + + M Y Y + PT Y P +Y +
Sbjct: 405 FAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYE 464
Query: 352 TYAAIPSLHFPATKGHLSNRAIIRAPSVREIYMNVPVGAAGVRGLGGRGYLAYTGLG 408
Y + +G + Y + VGA G G G RG G G
Sbjct: 465 DYYDYYGYDYHNYRGGYEDPYY--------GYEDFQVGARGRGGRGARGAAPSRGRG 513
>gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3
[Homo sapiens]
Length = 535
Score = 330 bits (845), Expect = 3e-90
Identities = 165/317 (52%), Positives = 222/317 (70%), Gaps = 8/317 (2%)
Query: 17 EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFIGKLPRDLFEDELIP 74
EA ++AL++RTGY+L GQRKYGGPPP + P G E+F+GK+PRDL+EDEL+P
Sbjct: 23 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVP 82
Query: 75 LCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASV 133
L EK G I+++R+MMD +G NRGYAF+TF K A+ A+K ++YEIR G+ LGVC SV
Sbjct: 83 LFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISV 142
Query: 134 DNCRLFVGGIPKTKKREEILSEMKKVT---EGVVDVIVYPSAADKTKNRGFAFVEYESHR 190
N RLFVG IPK K +E IL E KVT EG+VDVI+Y DK KNRGF F+EYE H+
Sbjct: 143 ANNRLFVGSIPKNKTKENILEEFSKVTGLTEGLVDVILYHQPDDKKKNRGFCFLEYEDHK 202
Query: 191 AAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKE 250
+AA ARR+L+ G++++WG+ + V+WA+P E D + M+ VK+L+VRNL + +EE++EK
Sbjct: 203 SAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKS 262
Query: 251 FNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYV 310
F+ G +ERVKK++DYAFVHF +R AV+AM +NGK ++G IE+ LAKP DK
Sbjct: 263 FSEF--GKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKE 320
Query: 311 RYTRGTGGRGTMLQGEY 327
R R T + Y
Sbjct: 321 RQAARQASRSTAYEDYY 337
>gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1
[Homo sapiens]
Length = 636
Score = 330 bits (845), Expect = 3e-90
Identities = 165/317 (52%), Positives = 222/317 (70%), Gaps = 8/317 (2%)
Query: 17 EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFIGKLPRDLFEDELIP 74
EA ++AL++RTGY+L GQRKYGGPPP + P G E+F+GK+PRDL+EDEL+P
Sbjct: 124 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVP 183
Query: 75 LCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASV 133
L EK G I+++R+MMD +G NRGYAF+TF K A+ A+K ++YEIR G+ LGVC SV
Sbjct: 184 LFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISV 243
Query: 134 DNCRLFVGGIPKTKKREEILSEMKKVT---EGVVDVIVYPSAADKTKNRGFAFVEYESHR 190
N RLFVG IPK K +E IL E KVT EG+VDVI+Y DK KNRGF F+EYE H+
Sbjct: 244 ANNRLFVGSIPKNKTKENILEEFSKVTGLTEGLVDVILYHQPDDKKKNRGFCFLEYEDHK 303
Query: 191 AAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKE 250
+AA ARR+L+ G++++WG+ + V+WA+P E D + M+ VK+L+VRNL + +EE++EK
Sbjct: 304 SAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKS 363
Query: 251 FNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYV 310
F+ G +ERVKK++DYAFVHF +R AV+AM +NGK ++G IE+ LAKP DK
Sbjct: 364 FSEF--GKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKE 421
Query: 311 RYTRGTGGRGTMLQGEY 327
R R T + Y
Sbjct: 422 RQAARQASRSTAYEDYY 438
>gi|228008398 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 3 [Homo sapiens]
Length = 527
Score = 285 bits (728), Expect = 1e-76
Identities = 172/417 (41%), Positives = 228/417 (54%), Gaps = 59/417 (14%)
Query: 6 KSGDGLSGTQK---EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFI 60
K G ++ + K EA ++AL++RTGY+L GQRKYGGPPP + P G EIF+
Sbjct: 107 KQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFV 166
Query: 61 GKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNY 119
GK+PRDLFEDEL+PL EK G I+++R+MMD G NRGYAFVTF K A+ A+K NN+
Sbjct: 167 GKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNH 226
Query: 120 EIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNR 179
EIR+G+ +GVC SV N RLFVG IPK+K +E+IL E KVTEG+ DVI+Y DK KNR
Sbjct: 227 EIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNR 286
Query: 180 GFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLM 239
GF F+EYE H+ AA VK+L+VRNL
Sbjct: 287 GFCFLEYEDHKTAA-----------------------------------QVKVLFVRNLA 311
Query: 240 LSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVT 299
+ +EE++EK F+ G +ERVKK++DYAF+HF R+ AV+AM+ +NGK L+G IE+
Sbjct: 312 NTVTEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIV 369
Query: 300 LAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTT--------TYLGAPVFYAPQ 351
AKP D+ R + + M Y Y + PT Y P +Y +
Sbjct: 370 FAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYE 429
Query: 352 TYAAIPSLHFPATKGHLSNRAIIRAPSVREIYMNVPVGAAGVRGLGGRGYLAYTGLG 408
Y + +G + Y + VGA G G G RG G G
Sbjct: 430 DYYDYYGYDYHNYRGGYEDPYY--------GYEDFQVGARGRGGRGARGAAPSRGRG 478
>gi|228008295 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 4 [Homo sapiens]
Length = 588
Score = 285 bits (728), Expect = 1e-76
Identities = 172/417 (41%), Positives = 228/417 (54%), Gaps = 59/417 (14%)
Query: 6 KSGDGLSGTQK---EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFI 60
K G ++ + K EA ++AL++RTGY+L GQRKYGGPPP + P G EIF+
Sbjct: 107 KQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFV 166
Query: 61 GKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNY 119
GK+PRDLFEDEL+PL EK G I+++R+MMD G NRGYAFVTF K A+ A+K NN+
Sbjct: 167 GKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNH 226
Query: 120 EIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNR 179
EIR+G+ +GVC SV N RLFVG IPK+K +E+IL E KVTEG+ DVI+Y DK KNR
Sbjct: 227 EIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNR 286
Query: 180 GFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLM 239
GF F+EYE H+ AA VK+L+VRNL
Sbjct: 287 GFCFLEYEDHKTAA-----------------------------------QVKVLFVRNLA 311
Query: 240 LSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVT 299
+ +EE++EK F+ G +ERVKK++DYAF+HF R+ AV+AM+ +NGK L+G IE+
Sbjct: 312 NTVTEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIV 369
Query: 300 LAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTT--------TYLGAPVFYAPQ 351
AKP D+ R + + M Y Y + PT Y P +Y +
Sbjct: 370 FAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYE 429
Query: 352 TYAAIPSLHFPATKGHLSNRAIIRAPSVREIYMNVPVGAAGVRGLGGRGYLAYTGLG 408
Y + +G + Y + VGA G G G RG G G
Sbjct: 430 DYYDYYGYDYHNYRGGYEDPYY--------GYEDFQVGARGRGGRGARGAAPSRGRG 478
>gi|34740339 dead end homolog 1 [Homo sapiens]
Length = 353
Score = 183 bits (464), Expect = 4e-46
Identities = 88/207 (42%), Positives = 136/207 (65%), Gaps = 2/207 (0%)
Query: 15 QKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIP 74
+ +AAL A V+ TG LVQ NGQRKYGGPPPGW +PP G E+FIG+LP+D++E +LIP
Sbjct: 17 ENKAALEAWVRETGIRLVQVNGQRKYGGPPPGWVGSPPPAGSEVFIGRLPQDVYEHQLIP 76
Query: 75 LCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVD 134
L +++G++YE R+MM F+G NRG+A+ +S++ A+ AI L+N+ +R L VC S +
Sbjct: 77 LFQRVGRLYEFRLMMTFSGLNRGFAYARYSSRRGAQAAIATLHNHPLRPSCPLLVCRSTE 136
Query: 135 NCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAM 194
C L V G+P R +L ++ + G+ + + PS A +++ SHRAAAM
Sbjct: 137 KCELSVDGLPPNLTRSALLLALQPLGPGLQEARLLPSPGPAPGQ--IALLKFSSHRAAAM 194
Query: 195 ARRKLLPGRIQLWGHGIAVDWAEPEVE 221
A++ L+ G+ L G +AV+W +P+++
Sbjct: 195 AKKALVEGQSHLCGEQVAVEWLKPDLK 221
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 86.3 bits (212), Expect = 7e-17
Identities = 80/284 (28%), Positives = 132/284 (46%), Gaps = 54/284 (19%)
Query: 58 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 117
+FI L + + L GKI ++M D G+ +GYAFV F N+ A AI+++N
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQGS-KGYAFVHFQNQSAADRAIEEMN 158
Query: 118 NYEIRNGRLLGVCASVDNCRLFVGGIPKTKKRE-EILSEMKKVT-------------EGV 163
G+LL C++FVG K RE E+ S+ + T E +
Sbjct: 159 ------GKLL------KGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERL 206
Query: 164 VDVI--------VYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRI--QLWGHGIAV 213
DV V K++GF FV ++SH AA A ++ I QL G A
Sbjct: 207 KDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQ 266
Query: 214 DWAEPEVEVDE--DTMSSVKI-------LYVRNLMLSTSEEMIEKEFNNIKPGAVERVKK 264
E + E+ + + + +I LY++NL + +E + EF++ G++ RVK
Sbjct: 267 KKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLRNEFSSF--GSISRVKV 324
Query: 265 IRD------YAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAK 302
+++ + + FS+ EDA +AM +NG++L P+ + LA+
Sbjct: 325 MQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQ 368
Score = 56.2 bits (134), Expect = 8e-08
Identities = 69/288 (23%), Positives = 125/288 (43%), Gaps = 37/288 (12%)
Query: 48 DAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNK 106
+ A R +++G L D+ ED L +G + +R+ D + GYA+V F
Sbjct: 2 NVAAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQL 61
Query: 107 VEAKNAIKQLNNYEIRNGRLLGVCASVDNCRL--------FVGGIPKT---KKREEILSE 155
+A+ A+ + N++I G+ + + S + L F+ + K+ K E S
Sbjct: 62 ADAQKALDTM-NFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSA 120
Query: 156 MKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMA----RRKLLPGRIQLWGHGI 211
K+ V +D ++G+AFV +++ AA A KLL G G
Sbjct: 121 FGKILSSKV-------MSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFK 173
Query: 212 AVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVK-------K 264
E E+ ++V Y++N +E ++ F+ K G VK K
Sbjct: 174 NRKDREAELRSKASEFTNV---YIKNFGGDMDDERLKDVFS--KYGKTLSVKVMTDSSGK 228
Query: 265 IRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLA-KPVDKDSYVR 311
+ + FV F + E A +A++ +NG+ ++G I V A K V++ + ++
Sbjct: 229 SKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELK 276
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 73.2 bits (178), Expect = 6e-13
Identities = 84/344 (24%), Positives = 150/344 (43%), Gaps = 62/344 (18%)
Query: 58 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 117
+FI L + + L G I +++ D NG+ +GYAFV F + A AI+++N
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS-KGYAFVHFETQEAADKAIEKMN 159
Query: 118 NYEIRNGRLLGVCASVDNCRLFVGGIPKTKKRE-EILSEMKKVT--------EGVVDVIV 168
G LL ++ ++FVG K+RE E+ ++ K+ T E V D +
Sbjct: 160 ------GMLL------NDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESL 207
Query: 169 YP--SAADKT-----------KNRGFAFVEYESHRAAAMARRKL----LPGRIQLWGHGI 211
S KT K++GF FV YE H A A ++ + G+I G
Sbjct: 208 KELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQ 267
Query: 212 AVDWAEPEVEVDEDTMSSVKI-------LYVRNLMLSTSEEMIEKEFNNIKPGAVERVK- 263
+ E++ + + +I LY++NL + +E + KEF+ G++ K
Sbjct: 268 KKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPF--GSITSAKV 325
Query: 264 -----KIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDK------DSYVRY 312
+ + + FV FS+ E+A +A+ +NG+++ P+ V LA+ ++ + Y++
Sbjct: 326 MLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQR 385
Query: 313 TRGTGG-RGTMLQGEYTYSLGQVYDPTTTYL-GAPVFYAPQTYA 354
G + ++ + G + P G P +Y P A
Sbjct: 386 VAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLA 429
Score = 59.7 bits (143), Expect = 7e-09
Identities = 62/271 (22%), Positives = 120/271 (44%), Gaps = 23/271 (8%)
Query: 58 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDF-NGNNRGYAFVTFSNKVEAKNAIKQL 116
+++G L D+ E L G + +R+ D + GYA+V F +A+ A+ +
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 117 NNYEIRNGRLLGVCASVDNCRLFVGGIPKT--KKREEILSE--MKKVTEGVVDVIVYPSA 172
N+++ G+ + + S + L G+ K ++ + + +++
Sbjct: 73 -NFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 173 ADKTKNRGFAFVEYESHRAAAMARRK----LLPGRIQLWGHGIAVDWAEPEVEVDEDTMS 228
D+ ++G+AFV +E+ AA A K LL R G + E E+ +
Sbjct: 132 CDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFT 191
Query: 229 SVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD-------YAFVHFSNREDAVE 281
+V Y++N +E +++ F+ G VK +RD + FV + EDA +
Sbjct: 192 NV---YIKNFGEEVDDESLKELFSQF--GKTLSVKVMRDPNGKSKGFGFVSYEKHEDANK 246
Query: 282 AMKALNGKVLDGSPIEVTLA-KPVDKDSYVR 311
A++ +NGK + G I V A K V++ + ++
Sbjct: 247 AVEEMNGKEISGKIIFVGRAQKKVERQAELK 277
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 73.2 bits (178), Expect = 6e-13
Identities = 84/344 (24%), Positives = 150/344 (43%), Gaps = 62/344 (18%)
Query: 58 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 117
+FI L + + L G I +++ D NG+ +GYAFV F + A AI+++N
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS-KGYAFVHFETQEAADKAIEKMN 159
Query: 118 NYEIRNGRLLGVCASVDNCRLFVGGIPKTKKRE-EILSEMKKVT--------EGVVDVIV 168
G LL ++ ++FVG K+RE E+ ++ K+ T E V D +
Sbjct: 160 ------GMLL------NDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESL 207
Query: 169 YP--SAADKT-----------KNRGFAFVEYESHRAAAMARRKL----LPGRIQLWGHGI 211
S KT K++GF FV YE H A A ++ + G+I G
Sbjct: 208 KELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQ 267
Query: 212 AVDWAEPEVEVDEDTMSSVKI-------LYVRNLMLSTSEEMIEKEFNNIKPGAVERVK- 263
+ E++ + + +I LY++NL + +E + KEF+ G++ K
Sbjct: 268 KKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPF--GSITSAKV 325
Query: 264 -----KIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDK------DSYVRY 312
+ + + FV FS+ E+A +A+ +NG+++ P+ V LA+ ++ + Y++
Sbjct: 326 MLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQR 385
Query: 313 TRGTGG-RGTMLQGEYTYSLGQVYDPTTTYL-GAPVFYAPQTYA 354
G + ++ + G + P G P +Y P A
Sbjct: 386 VAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLA 429
Score = 59.7 bits (143), Expect = 7e-09
Identities = 62/271 (22%), Positives = 120/271 (44%), Gaps = 23/271 (8%)
Query: 58 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDF-NGNNRGYAFVTFSNKVEAKNAIKQL 116
+++G L D+ E L G + +R+ D + GYA+V F +A+ A+ +
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 117 NNYEIRNGRLLGVCASVDNCRLFVGGIPKT--KKREEILSE--MKKVTEGVVDVIVYPSA 172
N+++ G+ + + S + L G+ K ++ + + +++
Sbjct: 73 -NFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 173 ADKTKNRGFAFVEYESHRAAAMARRK----LLPGRIQLWGHGIAVDWAEPEVEVDEDTMS 228
D+ ++G+AFV +E+ AA A K LL R G + E E+ +
Sbjct: 132 CDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFT 191
Query: 229 SVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD-------YAFVHFSNREDAVE 281
+V Y++N +E +++ F+ G VK +RD + FV + EDA +
Sbjct: 192 NV---YIKNFGEEVDDESLKELFSQF--GKTLSVKVMRDPNGKSKGFGFVSYEKHEDANK 246
Query: 282 AMKALNGKVLDGSPIEVTLA-KPVDKDSYVR 311
A++ +NGK + G I V A K V++ + ++
Sbjct: 247 AVEEMNGKEISGKIIFVGRAQKKVERQAELK 277
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 73.2 bits (178), Expect = 6e-13
Identities = 84/344 (24%), Positives = 150/344 (43%), Gaps = 62/344 (18%)
Query: 58 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 117
+FI L + + L G I +++ D NG+ +GYAFV F + A AI+++N
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS-KGYAFVHFETQEAADKAIEKMN 159
Query: 118 NYEIRNGRLLGVCASVDNCRLFVGGIPKTKKRE-EILSEMKKVT--------EGVVDVIV 168
G LL ++ ++FVG K+RE E+ ++ K+ T E V D +
Sbjct: 160 ------GMLL------NDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESL 207
Query: 169 YP--SAADKT-----------KNRGFAFVEYESHRAAAMARRKL----LPGRIQLWGHGI 211
S KT K++GF FV YE H A A ++ + G+I G
Sbjct: 208 KELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQ 267
Query: 212 AVDWAEPEVEVDEDTMSSVKI-------LYVRNLMLSTSEEMIEKEFNNIKPGAVERVK- 263
+ E++ + + +I LY++NL + +E + KEF+ G++ K
Sbjct: 268 KKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPF--GSITSAKV 325
Query: 264 -----KIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDK------DSYVRY 312
+ + + FV FS+ E+A +A+ +NG+++ P+ V LA+ ++ + Y++
Sbjct: 326 MLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQR 385
Query: 313 TRGTGG-RGTMLQGEYTYSLGQVYDPTTTYL-GAPVFYAPQTYA 354
G + ++ + G + P G P +Y P A
Sbjct: 386 VAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLA 429
Score = 59.7 bits (143), Expect = 7e-09
Identities = 62/271 (22%), Positives = 120/271 (44%), Gaps = 23/271 (8%)
Query: 58 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDF-NGNNRGYAFVTFSNKVEAKNAIKQL 116
+++G L D+ E L G + +R+ D + GYA+V F +A+ A+ +
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 117 NNYEIRNGRLLGVCASVDNCRLFVGGIPKT--KKREEILSE--MKKVTEGVVDVIVYPSA 172
N+++ G+ + + S + L G+ K ++ + + +++
Sbjct: 73 -NFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131
Query: 173 ADKTKNRGFAFVEYESHRAAAMARRK----LLPGRIQLWGHGIAVDWAEPEVEVDEDTMS 228
D+ ++G+AFV +E+ AA A K LL R G + E E+ +
Sbjct: 132 CDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFT 191
Query: 229 SVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD-------YAFVHFSNREDAVE 281
+V Y++N +E +++ F+ G VK +RD + FV + EDA +
Sbjct: 192 NV---YIKNFGEEVDDESLKELFSQF--GKTLSVKVMRDPNGKSKGFGFVSYEKHEDANK 246
Query: 282 AMKALNGKVLDGSPIEVTLA-KPVDKDSYVR 311
A++ +NGK + G I V A K V++ + ++
Sbjct: 247 AVEEMNGKEISGKIIFVGRAQKKVERQAELK 277
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 70.1 bits (170), Expect = 5e-12
Identities = 75/286 (26%), Positives = 119/286 (41%), Gaps = 58/286 (20%)
Query: 58 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 117
IF+ L + + L G I ++ D NG+ +GY FV F A+ AIK++N
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGS-KGYGFVHFETHEAAERAIKKMN 159
Query: 118 NYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSE---------MKKVTEGVVD--- 165
+ NGR ++FVG K+RE L +K E + D
Sbjct: 160 GM-LLNGR-----------KVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERL 207
Query: 166 ----------VIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDW 215
+ V + K++GF FV +E H A A ++ +L G I V
Sbjct: 208 KDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEM--NGKELNGKQIYVGR 265
Query: 216 AEPEVE-------------VDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERV 262
A+ +VE D T V LYV+NL +E + K F+ G +
Sbjct: 266 AQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPF--GTITSA 323
Query: 263 K------KIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAK 302
K + + + FV FS+ E+A +A+ +NG+++ P+ V LA+
Sbjct: 324 KVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQ 369
Score = 68.2 bits (165), Expect = 2e-11
Identities = 67/280 (23%), Positives = 121/280 (43%), Gaps = 19/280 (6%)
Query: 49 AAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDF-NGNNRGYAFVTFSNKV 107
+ P +++G L D+ E L G I +R+ D + YA+V F +
Sbjct: 4 STPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTK 63
Query: 108 EAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVV--- 164
+A++A+ +N +++ G+ + + S + L G+ + S K V
Sbjct: 64 DAEHALDTMN-FDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAF 122
Query: 165 -DVIVYPSAADKTKNRGFAFVEYESHRAAAMARRK----LLPGRIQLWGHGIAVDWAEPE 219
+++ D+ ++G+ FV +E+H AA A +K LL GR G + E E
Sbjct: 123 GNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAE 182
Query: 220 VEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVK-----KIRDYAFVHFS 274
+ +V Y++N +E ++ F P +V K + + FV F
Sbjct: 183 LGARAKEFPNV---YIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFE 239
Query: 275 NREDAVEAMKALNGKVLDGSPIEVTLA-KPVDKDSYVRYT 313
EDA +A+ +NGK L+G I V A K V++ + ++ T
Sbjct: 240 RHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRT 279
Score = 47.8 bits (112), Expect = 3e-05
Identities = 38/151 (25%), Positives = 72/151 (47%), Gaps = 24/151 (15%)
Query: 17 EAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCE------IFIGKLPRDLFED 70
EAA RA+ + G L NG++ + G E G ++I D+ ++
Sbjct: 149 EAAERAIKKMNGMLL---NGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDE 205
Query: 71 ELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVC 130
L L K G +++M D +G ++G+ FV+F +A+ A+ ++N E+ NG+
Sbjct: 206 RLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKEL-NGK----- 259
Query: 131 ASVDNCRLFVGGIPKTKKREEILSEMKKVTE 161
+++VG + +K+ E +E+K+ E
Sbjct: 260 ------QIYVG---RAQKKVERQTELKRTFE 281
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 69.3 bits (168), Expect = 9e-12
Identities = 92/362 (25%), Positives = 147/362 (40%), Gaps = 77/362 (21%)
Query: 58 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 117
IFI L + + L G I +++ D NG+ +GY FV F + A+ AI+++N
Sbjct: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS-KGYGFVHFETQEAAERAIEKMN 159
Query: 118 NYEIRNGRLLGVCASVDNCRLFVGGIPKTKKRE-EILSEMKKVT-------------EGV 163
G LL ++ ++FVG K+RE E+ + K+ T E +
Sbjct: 160 ------GMLL------NDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERL 207
Query: 164 VDVI--------VYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDW 215
D+ V + K++GF FV +E H A A ++ +L G I V
Sbjct: 208 KDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEM--NGKELNGKQIYVGR 265
Query: 216 AEPEVE-------------VDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERV 262
A+ +VE D T LYV+NL +E + KEF+ G +
Sbjct: 266 AQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPF--GTITSA 323
Query: 263 K------KIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGT 316
K + + + FV FS+ E+A +A+ +NG+++ P+ V LA+ ++
Sbjct: 324 KVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEE---------- 373
Query: 317 GGRGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRA 376
R L +Y + V + Y P A PS +F A NRA
Sbjct: 374 --RQAHLTNQYMQRMASVRAVPNPVINP---YQP----APPSGYFMAAIPQTQNRAAYYP 424
Query: 377 PS 378
PS
Sbjct: 425 PS 426
Score = 62.0 bits (149), Expect = 1e-09
Identities = 64/278 (23%), Positives = 119/278 (42%), Gaps = 19/278 (6%)
Query: 49 AAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDF-NGNNRGYAFVTFSNKV 107
+AP +++G L D+ E L G I +R+ D + GYA+V F
Sbjct: 4 SAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPA 63
Query: 108 EAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKT--KKREEILSE--MKKVTEGV 163
+A+ A+ +N +++ G+ + + S + L G+ K ++ + +
Sbjct: 64 DAERALDTMN-FDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAF 122
Query: 164 VDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRK----LLPGRIQLWGHGIAVDWAEPE 219
+++ D+ ++G+ FV +E+ AA A K LL R G + E E
Sbjct: 123 GNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAE 182
Query: 220 VEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVK-----KIRDYAFVHFS 274
+ ++V Y++N +E ++ F P +V K + + FV F
Sbjct: 183 LGARAKEFTNV---YIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFE 239
Query: 275 NREDAVEAMKALNGKVLDGSPIEVTLA-KPVDKDSYVR 311
EDA +A+ +NGK L+G I V A K V++ + ++
Sbjct: 240 RHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELK 277
Score = 44.3 bits (103), Expect = 3e-04
Identities = 37/152 (24%), Positives = 72/152 (47%), Gaps = 24/152 (15%)
Query: 16 KEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCE------IFIGKLPRDLFE 69
+EAA RA+ + G L N ++ + G E G ++I D+ +
Sbjct: 148 QEAAERAIEKMNGMLL---NDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDD 204
Query: 70 DELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGV 129
+ L L K G +++M D +G ++G+ FV+F +A+ A+ ++N E+ NG+
Sbjct: 205 ERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKEL-NGK---- 259
Query: 130 CASVDNCRLFVGGIPKTKKREEILSEMKKVTE 161
+++VG + +K+ E +E+K+ E
Sbjct: 260 -------QIYVG---RAQKKVERQTELKRKFE 281
>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
Length = 382
Score = 67.4 bits (163), Expect = 4e-11
Identities = 74/278 (26%), Positives = 124/278 (44%), Gaps = 41/278 (14%)
Query: 58 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAI---- 113
IFI L + + L L G I +++ D NG+ +GYA+V F + A AI
Sbjct: 108 IFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGS-KGYAYVHFDSLAAANRAIWHMN 166
Query: 114 -KQLNNYEIRNGRLLGVCASVDNCR---------LFVGGIPKTKKREEILSEMKKVTEGV 163
+LNN ++ GR R +FV I E+ L E+
Sbjct: 167 GVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEK-LKELFCEYGPT 225
Query: 164 VDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVE-- 221
V V A+ K+K GF FV YE+H AA A L I G + V A+ ++E
Sbjct: 226 ESVKVIRDASGKSK--GFGFVRYETHEAAQKAVLDLHGKSID--GKVLYVGRAQKKIERL 281
Query: 222 -----------VDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD--- 267
+ E + +Y++NL + ++E +++EF++ G++ R K + +
Sbjct: 282 AELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSF--GSISRAKVMMEVGQ 339
Query: 268 ---YAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAK 302
+ V FS+ E+A +A+ +NG+++ P+ VTL +
Sbjct: 340 GKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVTLGQ 377
Score = 34.3 bits (77), Expect = 0.33
Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 6/80 (7%)
Query: 233 LYVRNLMLSTSEEMIEKEFNNIKPGAVERV------KKIRDYAFVHFSNREDAVEAMKAL 286
LYV +L +E+M+ K+F P R+ + Y +V+F DA A+ +
Sbjct: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
Query: 287 NGKVLDGSPIEVTLAKPVDK 306
N +++G P + ++P D+
Sbjct: 80 NFDLINGKPFRLMWSQPDDR 99
Score = 33.9 bits (76), Expect = 0.43
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 9/78 (11%)
Query: 51 PPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAK 110
PP G I+I L + +++L G I ++MM+ G +G+ V FS+ EA
Sbjct: 299 PP--GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEV-GQGKGFGVVCFSSFEEAT 355
Query: 111 NAIKQLNNYEIRNGRLLG 128
A+ ++ NGR++G
Sbjct: 356 KAVDEM------NGRIVG 367
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 64.3 bits (155), Expect = 3e-10
Identities = 66/292 (22%), Positives = 128/292 (43%), Gaps = 23/292 (7%)
Query: 44 PPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTF 103
P G D+ + LP + +DEL + E +I ++ +G ++G A++ F
Sbjct: 381 PKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEI----RLVSKDGKSKGIAYIEF 436
Query: 104 SNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRL--FVGGIPKTKKREE---ILSEMK- 157
+ +A+ ++ EI +GR + + + + + + GG T E +LS +
Sbjct: 437 KTEADAEKTFEEKQGTEI-DGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSY 495
Query: 158 KVTEGVVDVIVYPSAADKT------KNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGI 211
TE + + + K K++G+AF+E+ S A A I+ G I
Sbjct: 496 SATEETLQEVFEKATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIE--GRAI 553
Query: 212 AVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKI---RDY 268
++ P + + S K L+V+ L T+EE +++ F+ + ++ + +
Sbjct: 554 RLELQGPRGSPNARSQPS-KTLFVKGLSEDTTEETLKESFDGSVRARIVTDRETGSSKGF 612
Query: 269 AFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRG 320
FV F++ EDA A +A+ +DG+ + + AKP + + G GG G
Sbjct: 613 GFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGRGGFG 664
>gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo
sapiens]
Length = 485
Score = 63.9 bits (154), Expect = 4e-10
Identities = 53/175 (30%), Positives = 86/175 (49%), Gaps = 15/175 (8%)
Query: 30 SLVQENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMM 89
S V +G GG P G ++F+G++PR L E +L PL E+ G+IYE+ ++
Sbjct: 22 SPVGSSGPEPPGGQPDGMKDLD---AIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLK 78
Query: 90 D-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNG--RLLGVCASVDNCR------LFV 140
D + G ++G AF+T+ + A A L+ + G R + V + R LFV
Sbjct: 79 DPYTGMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFV 138
Query: 141 GGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMA 195
G + K + E++L + GV+D D + ++G AFV++ SH A A
Sbjct: 139 GMLNKQQSEEDVLRLFQPF--GVIDECTVLRGPDGS-SKGCAFVKFSSHTEAQAA 190
Score = 45.1 bits (105), Expect = 2e-04
Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 3/87 (3%)
Query: 43 PPPGWDAAPPE--RGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGN-NRGYA 99
PPP E GC +FI LP++ + EL + G I ++ MD N ++ +
Sbjct: 385 PPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFG 444
Query: 100 FVTFSNKVEAKNAIKQLNNYEIRNGRL 126
FV+F N A+ AI+ +N ++I RL
Sbjct: 445 FVSFDNPASAQAAIQAMNGFQIGMKRL 471
Score = 41.2 bits (95), Expect = 0.003
Identities = 22/71 (30%), Positives = 41/71 (57%)
Query: 54 RGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAI 113
R ++F+G L + E++++ L + G I E ++ +G+++G AFV FS+ EA+ AI
Sbjct: 132 RDRKLFVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAI 191
Query: 114 KQLNNYEIRNG 124
L+ + G
Sbjct: 192 HALHGSQTMPG 202
Score = 31.6 bits (70), Expect = 2.2
Identities = 57/229 (24%), Positives = 96/229 (41%), Gaps = 37/229 (16%)
Query: 133 VDNCRLFVGGIPK---TKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESH 189
+D +LFVG IP+ K + + + ++ E V Y ++G AF+ Y +
Sbjct: 42 LDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGM-----HKGCAFLTYCAR 96
Query: 190 RAA-----AMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSE 244
+A A+ +K LPG + I V A+ E D + L+V L SE
Sbjct: 97 DSAIKAQTALHEQKTLPGMAR----PIQVKPADSESRGGRD-----RKLFVGMLNKQQSE 147
Query: 245 EMIEKEFNNIKPGAVERVKKIRD-------YAFVHFSNREDAVEAMKALNG-KVLDGSPI 296
E + + F G ++ +R AFV FS+ +A A+ AL+G + + G+
Sbjct: 148 EDVLRLFQPF--GVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHALHGSQTMPGASS 205
Query: 297 EVTLA-KPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTTTYLGA 344
+ + DK+ +R + G+ G T SL + P + Y A
Sbjct: 206 SLVVKFADTDKERTLRRMQQMVGQ----LGILTPSLTLPFSPYSAYAQA 250
>gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo
sapiens]
Length = 448
Score = 60.5 bits (145), Expect = 4e-09
Identities = 46/147 (31%), Positives = 76/147 (51%), Gaps = 11/147 (7%)
Query: 57 EIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQ 115
++FIG++PR+L E +L PL E+ GKIYE+ ++ D F G ++G AF+T+ + A A
Sbjct: 55 KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114
Query: 116 LNNYEIRNG--RLLGVCASVDNCR-----LFVGGIPKTKKREEILSEMKKVTEGVVDVIV 168
L+ + G R + V + R LFVG + K + +++ + G ++
Sbjct: 115 LHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLNKQQSEDDVRRLFEAF--GNIEECT 172
Query: 169 YPSAADKTKNRGFAFVEYESHRAAAMA 195
D ++G AFV+Y SH A A
Sbjct: 173 ILRGPD-GNSKGCAFVKYSSHAEAQAA 198
Score = 43.9 bits (102), Expect = 4e-04
Identities = 23/68 (33%), Positives = 39/68 (57%)
Query: 57 EIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQL 116
++F+G L + ED++ L E G I E ++ +GN++G AFV +S+ EA+ AI L
Sbjct: 143 KLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINAL 202
Query: 117 NNYEIRNG 124
+ + G
Sbjct: 203 HGSQTMPG 210
Score = 30.4 bits (67), Expect = 4.8
Identities = 43/168 (25%), Positives = 72/168 (42%), Gaps = 28/168 (16%)
Query: 134 DNCRLFVGGIPKT---KKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHR 190
D +LF+G IP+ K + + E K+ E V + ++G AF+ Y
Sbjct: 52 DAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGM-----HKGCAFLTYCERE 106
Query: 191 AA-----AMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEE 245
+A A+ +K LPG I V A+ E ++ + L+V L SE+
Sbjct: 107 SALKAQSALHEQKTLPGM----NRPIQVKPADSESRGED------RKLFVGMLNKQQSED 156
Query: 246 MIEK---EFNNIKPGAVERVK--KIRDYAFVHFSNREDAVEAMKALNG 288
+ + F NI+ + R + AFV +S+ +A A+ AL+G
Sbjct: 157 DVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHG 204
>gi|51948366 ribonucleoprotein, PTB-binding 2 [Homo sapiens]
Length = 678
Score = 60.1 bits (144), Expect = 6e-09
Identities = 66/251 (26%), Positives = 108/251 (43%), Gaps = 15/251 (5%)
Query: 57 EIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQL 116
+I + LP+D E+ L K Y+++ + N+ AFVT N +A+NAI+
Sbjct: 70 KILVKNLPQDSNCQEVHDLL----KDYDLKYC--YVDRNKRTAFVTLLNGEQAQNAIQMF 123
Query: 117 NNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKT 176
+ Y R G+ L V + L + +P + EE ++ +VY +
Sbjct: 124 HQYSFR-GKDLIVQLQPTDALLCITNVPISFTSEEFEELVRAYGNIERCFLVYSEVTGHS 182
Query: 177 KNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVR 236
K G+ FVEY AA AR +LL GR QL + W + + E S +
Sbjct: 183 K--GYGFVEYMKKDFAAKARLELL-GR-QLGASALFAQWMDVNLLASELIHSKCLCIDKL 238
Query: 237 NLMLSTSEEMIEKEFNNIKPG----AVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLD 292
SEE+++ + KP A + + +A V +S E A E +A +G +
Sbjct: 239 PSDYRDSEELLQIFSSVHKPVFCQLAQDEGSYVGGFAVVEYSTAEQAEEVQQAADGMTIK 298
Query: 293 GSPIEVTLAKP 303
GS ++V+ P
Sbjct: 299 GSKVQVSFCAP 309
>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
Length = 375
Score = 58.2 bits (139), Expect = 2e-08
Identities = 64/296 (21%), Positives = 121/296 (40%), Gaps = 38/296 (12%)
Query: 58 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 117
+++G L RD+ E ++ L +IG +M+MD GN+ Y FV F A A+ +N
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
Query: 118 NYEIRNGRLLGVCASVDNCR---------LFVGGIPKTKKREEILSEMKKVTEGVVDVIV 168
+I + A+ + + +FVG + E+I + +V
Sbjct: 68 GRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVV 127
Query: 169 YPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMS 228
A K+K G+ FV + + A A +++ G L G I +WA + + T
Sbjct: 128 KDMATGKSK--GYGFVSFFNKWDAENAIQQM--GGQWLGGRQIRTNWATRKPPAPKSTYE 183
Query: 229 SVK-----------------ILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRDYAFV 271
S +Y + +E+++ + F+ RV + Y+FV
Sbjct: 184 SNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFV 243
Query: 272 HFSNREDAVEAMKALNGKVLDGSPIE-------VTLAKPVDKDSYVRYTRGTGGRG 320
F++ E A A+ ++NG ++G ++ + + PV + + + Y + G G
Sbjct: 244 RFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQIGYPQPYGQWG 299
>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
Length = 386
Score = 58.2 bits (139), Expect = 2e-08
Identities = 65/307 (21%), Positives = 122/307 (39%), Gaps = 49/307 (15%)
Query: 58 IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 117
+++G L RD+ E ++ L +IG +M+MD GN+ Y FV F A A+ +N
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67
Query: 118 NYEIR--------------------NGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMK 157
+I + ++ S D+ +FVG + E+I +
Sbjct: 68 GRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFA 127
Query: 158 KVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAE 217
+V A K+K G+ FV + + A A +++ G L G I +WA
Sbjct: 128 PFGRISDARVVKDMATGKSK--GYGFVSFFNKWDAENAIQQM--GGQWLGGRQIRTNWAT 183
Query: 218 PEVEVDEDTMSSVK-----------------ILYVRNLMLSTSEEMIEKEFNNIKPGAVE 260
+ + T S +Y + +E+++ + F+
Sbjct: 184 RKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEI 243
Query: 261 RVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIE-------VTLAKPVDKDSYVRYT 313
RV + Y+FV F++ E A A+ ++NG ++G ++ + + PV + + + Y
Sbjct: 244 RVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQIGYP 303
Query: 314 RGTGGRG 320
+ G G
Sbjct: 304 QPYGQWG 310
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,882,629
Number of Sequences: 37866
Number of extensions: 1173189
Number of successful extensions: 4216
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 168
Number of HSP's successfully gapped in prelim test: 98
Number of HSP's that attempted gapping in prelim test: 3342
Number of HSP's gapped (non-prelim): 672
length of query: 594
length of database: 18,247,518
effective HSP length: 108
effective length of query: 486
effective length of database: 14,157,990
effective search space: 6880783140
effective search space used: 6880783140
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.