Guide to the Human Genome
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Search of human proteins with 20357572

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20357572 apobec-1 complementation factor isoform 1 [Homo
sapiens]
         (586 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20357572 apobec-1 complementation factor isoform 1 [Homo sapi...  1181   0.0  
gi|20357575 apobec-1 complementation factor isoform 2 [Homo sapi...  1174   0.0  
gi|20357578 apobec-1 complementation factor isoform 3 [Homo sapi...  1121   0.0  
gi|148833513 RNA binding motif protein 47 isoform a [Homo sapiens]    525   e-149
gi|148833511 RNA binding motif protein 47 isoform b [Homo sapiens]    486   e-137
gi|21450675 RNA binding motif protein 46 [Homo sapiens]               464   e-131
gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4...   335   7e-92
gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2 [...   335   7e-92
gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting ...   334   1e-91
gi|228008396 synaptotagmin binding, cytoplasmic RNA interacting ...   334   1e-91
gi|228008293 synaptotagmin binding, cytoplasmic RNA interacting ...   334   1e-91
gi|228008291 synaptotagmin binding, cytoplasmic RNA interacting ...   334   1e-91
gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3...   330   3e-90
gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1...   330   3e-90
gi|228008398 synaptotagmin binding, cytoplasmic RNA interacting ...   285   1e-76
gi|228008295 synaptotagmin binding, cytoplasmic RNA interacting ...   285   1e-76
gi|34740339 dead end homolog 1 [Homo sapiens]                         183   4e-46
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s...    86   7e-17
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho...    73   6e-13
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo...    73   6e-13
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho...    73   6e-13
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]      70   5e-12
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]      69   9e-12
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]      67   3e-11
gi|55956788 nucleolin [Homo sapiens]                                   64   3e-10
gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo sa...    64   4e-10
gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo s...    60   4e-09
gi|51948366 ribonucleoprotein, PTB-binding 2 [Homo sapiens]            60   6e-09
gi|188219593 TIA1 protein isoform 1 [Homo sapiens]                     58   2e-08
gi|188219591 TIA1 protein isoform 2 [Homo sapiens]                     58   2e-08

>gi|20357572 apobec-1 complementation factor isoform 1 [Homo
           sapiens]
          Length = 586

 Score = 1181 bits (3056), Expect = 0.0
 Identities = 586/586 (100%), Positives = 586/586 (100%)

Query: 1   MESNHKSGDGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFI 60
           MESNHKSGDGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFI
Sbjct: 1   MESNHKSGDGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFI 60

Query: 61  GKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYE 120
           GKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYE
Sbjct: 61  GKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYE 120

Query: 121 IRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRG 180
           IRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRG
Sbjct: 121 IRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRG 180

Query: 181 FAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLML 240
           FAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLML
Sbjct: 181 FAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLML 240

Query: 241 STSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTL 300
           STSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTL
Sbjct: 241 STSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTL 300

Query: 301 AKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLH 360
           AKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLH
Sbjct: 301 AKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLH 360

Query: 361 FPATKGHLSNRAIIRAPSVRGAAGVRGLGGRGYLAYTGLGRGYQVKGDKREDKLYDILPG 420
           FPATKGHLSNRAIIRAPSVRGAAGVRGLGGRGYLAYTGLGRGYQVKGDKREDKLYDILPG
Sbjct: 361 FPATKGHLSNRAIIRAPSVRGAAGVRGLGGRGYLAYTGLGRGYQVKGDKREDKLYDILPG 420

Query: 421 MELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKITIPAL 480
           MELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKITIPAL
Sbjct: 421 MELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKITIPAL 480

Query: 481 ASQNPAIHPFTPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAATAFPGYAV 540
           ASQNPAIHPFTPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAATAFPGYAV
Sbjct: 481 ASQNPAIHPFTPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAATAFPGYAV 540

Query: 541 PNATAPVSAAQLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF 586
           PNATAPVSAAQLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF
Sbjct: 541 PNATAPVSAAQLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF 586


>gi|20357575 apobec-1 complementation factor isoform 2 [Homo
           sapiens]
          Length = 594

 Score = 1174 bits (3037), Expect = 0.0
 Identities = 586/594 (98%), Positives = 586/594 (98%), Gaps = 8/594 (1%)

Query: 1   MESNHKSGDGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFI 60
           MESNHKSGDGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFI
Sbjct: 1   MESNHKSGDGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFI 60

Query: 61  GKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYE 120
           GKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYE
Sbjct: 61  GKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYE 120

Query: 121 IRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRG 180
           IRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRG
Sbjct: 121 IRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRG 180

Query: 181 FAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLML 240
           FAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLML
Sbjct: 181 FAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLML 240

Query: 241 STSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTL 300
           STSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTL
Sbjct: 241 STSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTL 300

Query: 301 AKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLH 360
           AKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLH
Sbjct: 301 AKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLH 360

Query: 361 FPATKGHLSNRAIIRAPSVR--------GAAGVRGLGGRGYLAYTGLGRGYQVKGDKRED 412
           FPATKGHLSNRAIIRAPSVR        GAAGVRGLGGRGYLAYTGLGRGYQVKGDKRED
Sbjct: 361 FPATKGHLSNRAIIRAPSVREIYMNVPVGAAGVRGLGGRGYLAYTGLGRGYQVKGDKRED 420

Query: 413 KLYDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFL 472
           KLYDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFL
Sbjct: 421 KLYDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFL 480

Query: 473 YKITIPALASQNPAIHPFTPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAA 532
           YKITIPALASQNPAIHPFTPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAA
Sbjct: 481 YKITIPALASQNPAIHPFTPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAA 540

Query: 533 TAFPGYAVPNATAPVSAAQLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF 586
           TAFPGYAVPNATAPVSAAQLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF
Sbjct: 541 TAFPGYAVPNATAPVSAAQLKQAVTLGQDLAAYTTYEVYPTFAVTARGDGYGTF 594


>gi|20357578 apobec-1 complementation factor isoform 3 [Homo
           sapiens]
          Length = 594

 Score = 1121 bits (2900), Expect = 0.0
 Identities = 557/568 (98%), Positives = 563/568 (99%), Gaps = 2/568 (0%)

Query: 19  ALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEK 78
           AL++++ +T   L +ENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEK
Sbjct: 29  ALQSIILQT--LLEKENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEK 86

Query: 79  IGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRL 138
           IGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRL
Sbjct: 87  IGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRL 146

Query: 139 FVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRK 198
           FVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRK
Sbjct: 147 FVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRK 206

Query: 199 LLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGA 258
           LLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGA
Sbjct: 207 LLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGA 266

Query: 259 VERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGG 318
           VERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGG
Sbjct: 267 VERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGG 326

Query: 319 RGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRAPS 378
           RGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRAPS
Sbjct: 327 RGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRAPS 386

Query: 379 VRGAAGVRGLGGRGYLAYTGLGRGYQVKGDKREDKLYDILPGMELTPMNPVTLKPQGIKL 438
           VRGAAGVRGLGGRGYLAYTGLGRGYQVKGDKREDKLYDILPGMELTPMNPVTLKPQGIKL
Sbjct: 387 VRGAAGVRGLGGRGYLAYTGLGRGYQVKGDKREDKLYDILPGMELTPMNPVTLKPQGIKL 446

Query: 439 APQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKITIPALASQNPAIHPFTPPKLSAF 498
           APQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKITIPALASQNPAIHPFTPPKLSAF
Sbjct: 447 APQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYKITIPALASQNPAIHPFTPPKLSAF 506

Query: 499 VDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAATAFPGYAVPNATAPVSAAQLKQAVTL 558
           VDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAATAFPGYAVPNATAPVSAAQLKQAVTL
Sbjct: 507 VDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAAATAFPGYAVPNATAPVSAAQLKQAVTL 566

Query: 559 GQDLAAYTTYEVYPTFAVTARGDGYGTF 586
           GQDLAAYTTYEVYPTFAVTARGDGYGTF
Sbjct: 567 GQDLAAYTTYEVYPTFAVTARGDGYGTF 594


>gi|148833513 RNA binding motif protein 47 isoform a [Homo sapiens]
          Length = 593

 Score =  525 bits (1352), Expect = e-149
 Identities = 288/580 (49%), Positives = 362/580 (62%), Gaps = 71/580 (12%)

Query: 3   SNHKSGDGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFIGK 62
           S+ K  +G++G   EAAL AL++RTGYS+VQENGQRKYGGPPPGW+   P+RGCE+F+GK
Sbjct: 18  SSAKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPGWEGPHPQRGCEVFVGK 77

Query: 63  LPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIR 122
           +PRD++EDEL+P+ E +G+IYE+R+MMDF+G NRGYAFV + +K EAK A+++LNNYEIR
Sbjct: 78  IPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELNNYEIR 137

Query: 123 NGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFA 182
            GRLLGVC SVDNCRLF+GGIPK KKREEIL E+ KVTEGV+DVIVY SAADK KNRGFA
Sbjct: 138 PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFA 197

Query: 183 FVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLST 242
           FVEYESHRAAAMARRKL+PGRIQLWGH IAVDWAEPE++VDED M +VKILYVRNLM+ T
Sbjct: 198 FVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIET 257

Query: 243 SEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAK 302
           +E+ I+K F    PG VERVKKIRDYAFVHF++REDAV AM  LNG  L+GS +EVTLAK
Sbjct: 258 TEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAK 317

Query: 303 PVDKDSYVRY---TRGTGGRGTMLQGEYTYSLGQVYDP-TTTYLGAPVFYAPQTYAAI-- 356
           PVDK+ Y RY    RG G      Q  Y YS     DP T  Y G P       Y A+  
Sbjct: 318 PVDKEQYSRYQKAARGGGAAEAAQQPSYVYSC----DPYTLAYYGYP-------YNALIG 366

Query: 357 PSLHFPATKGHLSNRAIIRAPSVRGAAGVRGLGGRG-YLAYTGLGRG----YQVKGDKRE 411
           P+  +    G +  R        RGAAG R  G RG YL     GRG    Y     K++
Sbjct: 367 PNRDYFVKAGSIRGRG-------RGAAGNRAPGPRGSYLGGYSAGRGIYSRYHEGKGKQQ 419

Query: 412 DKLYDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLF 471
           +K Y+++P +E+  +NPV +KP                                      
Sbjct: 420 EKGYELVPNLEIPTVNPVAIKPG------------------------------------- 442

Query: 472 LYKITIPALASQNPAIHPFTPPKLSAFVDEAKTYAAEYTLQTLGIPTDGGDGTMATAAAA 531
              + IPA+ +Q         PK+   +++ K +  E+ +  + +  D      A AAAA
Sbjct: 443 --TVAIPAIGAQYSMFPAAPAPKM---IEDGKIHTVEHMISPIAVQPDPASAAAAAAAAA 497

Query: 532 ATAFPGYAVPNATAPVSAAQLKQAVTLGQDLAAYTTYEVY 571
           A A       +   P     +    T+  ++    T  +Y
Sbjct: 498 AAAAAVIPTVSTPPPFQGRPITPVYTVAPNVQRIPTAGIY 537


>gi|148833511 RNA binding motif protein 47 isoform b [Homo sapiens]
          Length = 524

 Score =  486 bits (1252), Expect = e-137
 Identities = 238/347 (68%), Positives = 280/347 (80%), Gaps = 8/347 (2%)

Query: 3   SNHKSGDGLSGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFIGK 62
           S+ K  +G++G   EAAL AL++RTGYS+VQENGQRKYGGPPPGW+   P+RGCE+F+GK
Sbjct: 18  SSAKVPEGVAGAPNEAALLALMERTGYSMVQENGQRKYGGPPPGWEGPHPQRGCEVFVGK 77

Query: 63  LPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIR 122
           +PRD++EDEL+P+ E +G+IYE+R+MMDF+G NRGYAFV + +K EAK A+++LNNYEIR
Sbjct: 78  IPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVRELNNYEIR 137

Query: 123 NGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFA 182
            GRLLGVC SVDNCRLF+GGIPK KKREEIL E+ KVTEGV+DVIVY SAADK KNRGFA
Sbjct: 138 PGRLLGVCCSVDNCRLFIGGIPKMKKREEILEEIAKVTEGVLDVIVYASAADKMKNRGFA 197

Query: 183 FVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLST 242
           FVEYESHRAAAMARRKL+PGRIQLWGH IAVDWAEPE++VDED M +VKILYVRNLM+ T
Sbjct: 198 FVEYESHRAAAMARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIET 257

Query: 243 SEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAK 302
           +E+ I+K F    PG VERVKKIRDYAFVHF++REDAV AM  LNG  L+GS +EVTLAK
Sbjct: 258 TEDTIKKSFGQFNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLAK 317

Query: 303 PVDKDSYVRY---TRGTGGRGTMLQGEYTYSLGQVYDP-TTTYLGAP 345
           PVDK+ Y RY    RG G      Q  Y YS     DP T  Y G P
Sbjct: 318 PVDKEQYSRYQKAARGGGAAEAAQQPSYVYSC----DPYTLAYYGYP 360


>gi|21450675 RNA binding motif protein 46 [Homo sapiens]
          Length = 533

 Score =  464 bits (1195), Expect = e-131
 Identities = 216/297 (72%), Positives = 258/297 (86%)

Query: 12  SGTQKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDE 71
           +G Q EAAL AL+++TGY++VQENGQRK+GGPPPGW+  PP RGCE+F+GK+PRD++EDE
Sbjct: 17  TGIQNEAALLALMEKTGYNMVQENGQRKFGGPPPGWEGPPPPRGCEVFVGKIPRDMYEDE 76

Query: 72  LIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCA 131
           L+P+ E+ GKIYE R+MM+F+G NRGYAFV ++ K EA+ AI+ LNNYEIR G+ +GVC 
Sbjct: 77  LVPVFERAGKIYEFRLMMEFSGENRGYAFVMYTTKEEAQLAIRILNNYEIRPGKFIGVCV 136

Query: 132 SVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRA 191
           S+DNCRLF+G IPK KK+EEIL EMKKVTEGVVDVIVYPSA DKTKNRGFAFVEYESHRA
Sbjct: 137 SLDNCRLFIGAIPKEKKKEEILDEMKKVTEGVVDVIVYPSATDKTKNRGFAFVEYESHRA 196

Query: 192 AAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEF 251
           AAMARRKL+PG  QLWGH I VDWA+PE EVDE+TM  VK+LYVRNLM+ST+EE I+ EF
Sbjct: 197 AAMARRKLIPGTFQLWGHTIQVDWADPEKEVDEETMQRVKVLYVRNLMISTTEETIKAEF 256

Query: 252 NNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDS 308
           N  KPGAVERVKK+RDYAFVHF NREDAV AM  +NGK +DG+ IEVTLAKPV+K++
Sbjct: 257 NKFKPGAVERVKKLRDYAFVHFFNREDAVAAMSVMNGKCIDGASIEVTLAKPVNKEN 313



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 39/97 (40%), Positives = 56/97 (57%), Gaps = 2/97 (2%)

Query: 415 YDILPGMELTPMNPVTLKPQGIKLAPQILEEICQKNNWGQPVYQLHSAIGQDQRQLFLYK 474
           Y   PG +LTP++  +LK      A   L+  C KNNW  P Y L+S   QD + L +YK
Sbjct: 370 YPFYPGTKLTPISMYSLKSNHFNSAVMHLDYYCNKNNWAPPEYYLYSTTSQDGKVLLVYK 429

Query: 475 ITIPALASQNPAIHPFTPPKLSAFVDEAKTYAAEYTL 511
           I IPA+A+ + +   F P KL   +++AK  AA++TL
Sbjct: 430 IVIPAIANGSQSY--FMPDKLCTTLEDAKELAAQFTL 464


>gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4
           [Homo sapiens]
          Length = 532

 Score =  335 bits (859), Expect = 7e-92
 Identities = 165/314 (52%), Positives = 222/314 (70%), Gaps = 5/314 (1%)

Query: 17  EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFIGKLPRDLFEDELIP 74
           EA ++AL++RTGY+L    GQRKYGGPPP   +    P  G E+F+GK+PRDL+EDEL+P
Sbjct: 23  EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVP 82

Query: 75  LCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASV 133
           L EK G I+++R+MMD  +G NRGYAF+TF  K  A+ A+K  ++YEIR G+ LGVC SV
Sbjct: 83  LFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISV 142

Query: 134 DNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAA 193
            N RLFVG IPK K +E IL E  KVTEG+VDVI+Y    DK KNRGF F+EYE H++AA
Sbjct: 143 ANNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAA 202

Query: 194 MARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNN 253
            ARR+L+ G++++WG+ + V+WA+P  E D + M+ VK+L+VRNL  + +EE++EK F+ 
Sbjct: 203 QARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSE 262

Query: 254 IKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYT 313
              G +ERVKK++DYAFVHF +R  AV+AM  +NGK ++G  IE+ LAKP DK    R  
Sbjct: 263 F--GKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQA 320

Query: 314 RGTGGRGTMLQGEY 327
                R T  +  Y
Sbjct: 321 ARQASRSTAYEDYY 334


>gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2
           [Homo sapiens]
          Length = 633

 Score =  335 bits (859), Expect = 7e-92
 Identities = 165/314 (52%), Positives = 222/314 (70%), Gaps = 5/314 (1%)

Query: 17  EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFIGKLPRDLFEDELIP 74
           EA ++AL++RTGY+L    GQRKYGGPPP   +    P  G E+F+GK+PRDL+EDEL+P
Sbjct: 124 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVP 183

Query: 75  LCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASV 133
           L EK G I+++R+MMD  +G NRGYAF+TF  K  A+ A+K  ++YEIR G+ LGVC SV
Sbjct: 184 LFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISV 243

Query: 134 DNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAA 193
            N RLFVG IPK K +E IL E  KVTEG+VDVI+Y    DK KNRGF F+EYE H++AA
Sbjct: 244 ANNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAA 303

Query: 194 MARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNN 253
            ARR+L+ G++++WG+ + V+WA+P  E D + M+ VK+L+VRNL  + +EE++EK F+ 
Sbjct: 304 QARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSE 363

Query: 254 IKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYT 313
              G +ERVKK++DYAFVHF +R  AV+AM  +NGK ++G  IE+ LAKP DK    R  
Sbjct: 364 F--GKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKERQA 421

Query: 314 RGTGGRGTMLQGEY 327
                R T  +  Y
Sbjct: 422 ARQASRSTAYEDYY 435


>gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 6 [Homo sapiens]
          Length = 562

 Score =  334 bits (857), Expect = 1e-91
 Identities = 183/409 (44%), Positives = 250/409 (61%), Gaps = 16/409 (3%)

Query: 6   KSGDGLSGTQK---EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFI 60
           K G  ++ + K   EA ++AL++RTGY+L    GQRKYGGPPP   +    P  G EIF+
Sbjct: 107 KQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFV 166

Query: 61  GKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNY 119
           GK+PRDLFEDEL+PL EK G I+++R+MMD   G NRGYAFVTF  K  A+ A+K  NN+
Sbjct: 167 GKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNH 226

Query: 120 EIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNR 179
           EIR+G+ +GVC SV N RLFVG IPK+K +E+IL E  KVTEG+ DVI+Y    DK KNR
Sbjct: 227 EIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNR 286

Query: 180 GFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLM 239
           GF F+EYE H+ AA ARR+L+ G++++WG+   V+WA+P  + D + M+ VK+L+VRNL 
Sbjct: 287 GFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLA 346

Query: 240 LSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVT 299
            + +EE++EK F+    G +ERVKK++DYAF+HF  R+ AV+AM+ +NGK L+G  IE+ 
Sbjct: 347 NTVTEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIV 404

Query: 300 LAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTT--------TYLGAPVFYAPQ 351
            AKP D+    R  +    +  M    Y Y    +  PT          Y   P +Y  +
Sbjct: 405 FAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYE 464

Query: 352 TYAAIPSLHFPATKGHLSNRAIIRAPSVRGAAGVRGLGGRGYLAYTGLG 400
            Y       +   +G   +          GA G  G G RG     G G
Sbjct: 465 DYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRG 513


>gi|228008396 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 2 [Homo sapiens]
          Length = 464

 Score =  334 bits (857), Expect = 1e-91
 Identities = 183/409 (44%), Positives = 250/409 (61%), Gaps = 16/409 (3%)

Query: 6   KSGDGLSGTQK---EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFI 60
           K G  ++ + K   EA ++AL++RTGY+L    GQRKYGGPPP   +    P  G EIF+
Sbjct: 9   KQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFV 68

Query: 61  GKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNY 119
           GK+PRDLFEDEL+PL EK G I+++R+MMD   G NRGYAFVTF  K  A+ A+K  NN+
Sbjct: 69  GKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNH 128

Query: 120 EIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNR 179
           EIR+G+ +GVC SV N RLFVG IPK+K +E+IL E  KVTEG+ DVI+Y    DK KNR
Sbjct: 129 EIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNR 188

Query: 180 GFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLM 239
           GF F+EYE H+ AA ARR+L+ G++++WG+   V+WA+P  + D + M+ VK+L+VRNL 
Sbjct: 189 GFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLA 248

Query: 240 LSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVT 299
            + +EE++EK F+    G +ERVKK++DYAF+HF  R+ AV+AM+ +NGK L+G  IE+ 
Sbjct: 249 NTVTEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIV 306

Query: 300 LAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTT--------TYLGAPVFYAPQ 351
            AKP D+    R  +    +  M    Y Y    +  PT          Y   P +Y  +
Sbjct: 307 FAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYE 366

Query: 352 TYAAIPSLHFPATKGHLSNRAIIRAPSVRGAAGVRGLGGRGYLAYTGLG 400
            Y       +   +G   +          GA G  G G RG     G G
Sbjct: 367 DYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRG 415


>gi|228008293 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 5 [Homo sapiens]
          Length = 561

 Score =  334 bits (857), Expect = 1e-91
 Identities = 183/409 (44%), Positives = 250/409 (61%), Gaps = 16/409 (3%)

Query: 6   KSGDGLSGTQK---EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFI 60
           K G  ++ + K   EA ++AL++RTGY+L    GQRKYGGPPP   +    P  G EIF+
Sbjct: 107 KQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFV 166

Query: 61  GKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNY 119
           GK+PRDLFEDEL+PL EK G I+++R+MMD   G NRGYAFVTF  K  A+ A+K  NN+
Sbjct: 167 GKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNH 226

Query: 120 EIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNR 179
           EIR+G+ +GVC SV N RLFVG IPK+K +E+IL E  KVTEG+ DVI+Y    DK KNR
Sbjct: 227 EIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNR 286

Query: 180 GFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLM 239
           GF F+EYE H+ AA ARR+L+ G++++WG+   V+WA+P  + D + M+ VK+L+VRNL 
Sbjct: 287 GFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLA 346

Query: 240 LSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVT 299
            + +EE++EK F+    G +ERVKK++DYAF+HF  R+ AV+AM+ +NGK L+G  IE+ 
Sbjct: 347 NTVTEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIV 404

Query: 300 LAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTT--------TYLGAPVFYAPQ 351
            AKP D+    R  +    +  M    Y Y    +  PT          Y   P +Y  +
Sbjct: 405 FAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYE 464

Query: 352 TYAAIPSLHFPATKGHLSNRAIIRAPSVRGAAGVRGLGGRGYLAYTGLG 400
            Y       +   +G   +          GA G  G G RG     G G
Sbjct: 465 DYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRG 513


>gi|228008291 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 1 [Homo sapiens]
          Length = 623

 Score =  334 bits (857), Expect = 1e-91
 Identities = 183/409 (44%), Positives = 250/409 (61%), Gaps = 16/409 (3%)

Query: 6   KSGDGLSGTQK---EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFI 60
           K G  ++ + K   EA ++AL++RTGY+L    GQRKYGGPPP   +    P  G EIF+
Sbjct: 107 KQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFV 166

Query: 61  GKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNY 119
           GK+PRDLFEDEL+PL EK G I+++R+MMD   G NRGYAFVTF  K  A+ A+K  NN+
Sbjct: 167 GKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNH 226

Query: 120 EIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNR 179
           EIR+G+ +GVC SV N RLFVG IPK+K +E+IL E  KVTEG+ DVI+Y    DK KNR
Sbjct: 227 EIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNR 286

Query: 180 GFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLM 239
           GF F+EYE H+ AA ARR+L+ G++++WG+   V+WA+P  + D + M+ VK+L+VRNL 
Sbjct: 287 GFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLA 346

Query: 240 LSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVT 299
            + +EE++EK F+    G +ERVKK++DYAF+HF  R+ AV+AM+ +NGK L+G  IE+ 
Sbjct: 347 NTVTEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIV 404

Query: 300 LAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTT--------TYLGAPVFYAPQ 351
            AKP D+    R  +    +  M    Y Y    +  PT          Y   P +Y  +
Sbjct: 405 FAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYE 464

Query: 352 TYAAIPSLHFPATKGHLSNRAIIRAPSVRGAAGVRGLGGRGYLAYTGLG 400
            Y       +   +G   +          GA G  G G RG     G G
Sbjct: 465 DYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRG 513


>gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3
           [Homo sapiens]
          Length = 535

 Score =  330 bits (845), Expect = 3e-90
 Identities = 165/317 (52%), Positives = 222/317 (70%), Gaps = 8/317 (2%)

Query: 17  EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFIGKLPRDLFEDELIP 74
           EA ++AL++RTGY+L    GQRKYGGPPP   +    P  G E+F+GK+PRDL+EDEL+P
Sbjct: 23  EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVP 82

Query: 75  LCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASV 133
           L EK G I+++R+MMD  +G NRGYAF+TF  K  A+ A+K  ++YEIR G+ LGVC SV
Sbjct: 83  LFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISV 142

Query: 134 DNCRLFVGGIPKTKKREEILSEMKKVT---EGVVDVIVYPSAADKTKNRGFAFVEYESHR 190
            N RLFVG IPK K +E IL E  KVT   EG+VDVI+Y    DK KNRGF F+EYE H+
Sbjct: 143 ANNRLFVGSIPKNKTKENILEEFSKVTGLTEGLVDVILYHQPDDKKKNRGFCFLEYEDHK 202

Query: 191 AAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKE 250
           +AA ARR+L+ G++++WG+ + V+WA+P  E D + M+ VK+L+VRNL  + +EE++EK 
Sbjct: 203 SAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKS 262

Query: 251 FNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYV 310
           F+    G +ERVKK++DYAFVHF +R  AV+AM  +NGK ++G  IE+ LAKP DK    
Sbjct: 263 FSEF--GKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKE 320

Query: 311 RYTRGTGGRGTMLQGEY 327
           R       R T  +  Y
Sbjct: 321 RQAARQASRSTAYEDYY 337


>gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1
           [Homo sapiens]
          Length = 636

 Score =  330 bits (845), Expect = 3e-90
 Identities = 165/317 (52%), Positives = 222/317 (70%), Gaps = 8/317 (2%)

Query: 17  EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFIGKLPRDLFEDELIP 74
           EA ++AL++RTGY+L    GQRKYGGPPP   +    P  G E+F+GK+PRDL+EDEL+P
Sbjct: 124 EAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGKIPRDLYEDELVP 183

Query: 75  LCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASV 133
           L EK G I+++R+MMD  +G NRGYAF+TF  K  A+ A+K  ++YEIR G+ LGVC SV
Sbjct: 184 LFEKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISV 243

Query: 134 DNCRLFVGGIPKTKKREEILSEMKKVT---EGVVDVIVYPSAADKTKNRGFAFVEYESHR 190
            N RLFVG IPK K +E IL E  KVT   EG+VDVI+Y    DK KNRGF F+EYE H+
Sbjct: 244 ANNRLFVGSIPKNKTKENILEEFSKVTGLTEGLVDVILYHQPDDKKKNRGFCFLEYEDHK 303

Query: 191 AAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKE 250
           +AA ARR+L+ G++++WG+ + V+WA+P  E D + M+ VK+L+VRNL  + +EE++EK 
Sbjct: 304 SAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKS 363

Query: 251 FNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYV 310
           F+    G +ERVKK++DYAFVHF +R  AV+AM  +NGK ++G  IE+ LAKP DK    
Sbjct: 364 FSEF--GKLERVKKLKDYAFVHFEDRGAAVKAMDEMNGKEIEGEEIEIVLAKPPDKKRKE 421

Query: 311 RYTRGTGGRGTMLQGEY 327
           R       R T  +  Y
Sbjct: 422 RQAARQASRSTAYEDYY 438


>gi|228008398 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 3 [Homo sapiens]
          Length = 527

 Score =  285 bits (728), Expect = 1e-76
 Identities = 170/409 (41%), Positives = 225/409 (55%), Gaps = 51/409 (12%)

Query: 6   KSGDGLSGTQK---EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFI 60
           K G  ++ + K   EA ++AL++RTGY+L    GQRKYGGPPP   +    P  G EIF+
Sbjct: 107 KQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFV 166

Query: 61  GKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNY 119
           GK+PRDLFEDEL+PL EK G I+++R+MMD   G NRGYAFVTF  K  A+ A+K  NN+
Sbjct: 167 GKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNH 226

Query: 120 EIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNR 179
           EIR+G+ +GVC SV N RLFVG IPK+K +E+IL E  KVTEG+ DVI+Y    DK KNR
Sbjct: 227 EIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNR 286

Query: 180 GFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLM 239
           GF F+EYE H+ AA                                    VK+L+VRNL 
Sbjct: 287 GFCFLEYEDHKTAA-----------------------------------QVKVLFVRNLA 311

Query: 240 LSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVT 299
            + +EE++EK F+    G +ERVKK++DYAF+HF  R+ AV+AM+ +NGK L+G  IE+ 
Sbjct: 312 NTVTEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIV 369

Query: 300 LAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTT--------TYLGAPVFYAPQ 351
            AKP D+    R  +    +  M    Y Y    +  PT          Y   P +Y  +
Sbjct: 370 FAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYE 429

Query: 352 TYAAIPSLHFPATKGHLSNRAIIRAPSVRGAAGVRGLGGRGYLAYTGLG 400
            Y       +   +G   +          GA G  G G RG     G G
Sbjct: 430 DYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRG 478


>gi|228008295 synaptotagmin binding, cytoplasmic RNA interacting
           protein isoform 4 [Homo sapiens]
          Length = 588

 Score =  285 bits (728), Expect = 1e-76
 Identities = 170/409 (41%), Positives = 225/409 (55%), Gaps = 51/409 (12%)

Query: 6   KSGDGLSGTQK---EAALRALVQRTGYSLVQENGQRKYGGPPPG--WDAAPPERGCEIFI 60
           K G  ++ + K   EA ++AL++RTGY+L    GQRKYGGPPP   +    P  G EIF+
Sbjct: 107 KQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFV 166

Query: 61  GKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQLNNY 119
           GK+PRDLFEDEL+PL EK G I+++R+MMD   G NRGYAFVTF  K  A+ A+K  NN+
Sbjct: 167 GKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNH 226

Query: 120 EIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNR 179
           EIR+G+ +GVC SV N RLFVG IPK+K +E+IL E  KVTEG+ DVI+Y    DK KNR
Sbjct: 227 EIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNR 286

Query: 180 GFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLM 239
           GF F+EYE H+ AA                                    VK+L+VRNL 
Sbjct: 287 GFCFLEYEDHKTAA-----------------------------------QVKVLFVRNLA 311

Query: 240 LSTSEEMIEKEFNNIKPGAVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVT 299
            + +EE++EK F+    G +ERVKK++DYAF+HF  R+ AV+AM+ +NGK L+G  IE+ 
Sbjct: 312 NTVTEEILEKAFSQF--GKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIV 369

Query: 300 LAKPVDKDSYVRYTRGTGGRGTMLQGEYTYSLGQVYDPTT--------TYLGAPVFYAPQ 351
            AKP D+    R  +    +  M    Y Y    +  PT          Y   P +Y  +
Sbjct: 370 FAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYE 429

Query: 352 TYAAIPSLHFPATKGHLSNRAIIRAPSVRGAAGVRGLGGRGYLAYTGLG 400
            Y       +   +G   +          GA G  G G RG     G G
Sbjct: 430 DYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRG 478


>gi|34740339 dead end homolog 1 [Homo sapiens]
          Length = 353

 Score =  183 bits (464), Expect = 4e-46
 Identities = 88/207 (42%), Positives = 136/207 (65%), Gaps = 2/207 (0%)

Query: 15  QKEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIP 74
           + +AAL A V+ TG  LVQ NGQRKYGGPPPGW  +PP  G E+FIG+LP+D++E +LIP
Sbjct: 17  ENKAALEAWVRETGIRLVQVNGQRKYGGPPPGWVGSPPPAGSEVFIGRLPQDVYEHQLIP 76

Query: 75  LCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVCASVD 134
           L +++G++YE R+MM F+G NRG+A+  +S++  A+ AI  L+N+ +R    L VC S +
Sbjct: 77  LFQRVGRLYEFRLMMTFSGLNRGFAYARYSSRRGAQAAIATLHNHPLRPSCPLLVCRSTE 136

Query: 135 NCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAM 194
            C L V G+P    R  +L  ++ +  G+ +  + PS          A +++ SHRAAAM
Sbjct: 137 KCELSVDGLPPNLTRSALLLALQPLGPGLQEARLLPSPGPAPGQ--IALLKFSSHRAAAM 194

Query: 195 ARRKLLPGRIQLWGHGIAVDWAEPEVE 221
           A++ L+ G+  L G  +AV+W +P+++
Sbjct: 195 AKKALVEGQSHLCGEQVAVEWLKPDLK 221


>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
           sapiens]
          Length = 370

 Score = 86.3 bits (212), Expect = 7e-17
 Identities = 80/284 (28%), Positives = 132/284 (46%), Gaps = 54/284 (19%)

Query: 58  IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 117
           +FI  L + +    L       GKI   ++M D  G+ +GYAFV F N+  A  AI+++N
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQGS-KGYAFVHFQNQSAADRAIEEMN 158

Query: 118 NYEIRNGRLLGVCASVDNCRLFVGGIPKTKKRE-EILSEMKKVT-------------EGV 163
                 G+LL        C++FVG     K RE E+ S+  + T             E +
Sbjct: 159 ------GKLL------KGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERL 206

Query: 164 VDVI--------VYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRI--QLWGHGIAV 213
            DV         V        K++GF FV ++SH AA  A  ++    I  QL   G A 
Sbjct: 207 KDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQ 266

Query: 214 DWAEPEVEVDE--DTMSSVKI-------LYVRNLMLSTSEEMIEKEFNNIKPGAVERVKK 264
              E + E+ +  + +   +I       LY++NL  +  +E +  EF++   G++ RVK 
Sbjct: 267 KKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLRNEFSSF--GSISRVKV 324

Query: 265 IRD------YAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAK 302
           +++      +  + FS+ EDA +AM  +NG++L   P+ + LA+
Sbjct: 325 MQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQ 368



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 69/288 (23%), Positives = 125/288 (43%), Gaps = 37/288 (12%)

Query: 48  DAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNK 106
           + A   R   +++G L  D+ ED L      +G +  +R+  D     + GYA+V F   
Sbjct: 2   NVAAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQL 61

Query: 107 VEAKNAIKQLNNYEIRNGRLLGVCASVDNCRL--------FVGGIPKT---KKREEILSE 155
            +A+ A+  + N++I  G+ + +  S  +  L        F+  + K+   K   E  S 
Sbjct: 62  ADAQKALDTM-NFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSA 120

Query: 156 MKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMA----RRKLLPGRIQLWGHGI 211
             K+    V        +D   ++G+AFV +++  AA  A      KLL G     G   
Sbjct: 121 FGKILSSKV-------MSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFK 173

Query: 212 AVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVK-------K 264
                E E+       ++V   Y++N      +E ++  F+  K G    VK       K
Sbjct: 174 NRKDREAELRSKASEFTNV---YIKNFGGDMDDERLKDVFS--KYGKTLSVKVMTDSSGK 228

Query: 265 IRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLA-KPVDKDSYVR 311
            + + FV F + E A +A++ +NG+ ++G  I V  A K V++ + ++
Sbjct: 229 SKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELK 276


>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
           sapiens]
          Length = 631

 Score = 73.2 bits (178), Expect = 6e-13
 Identities = 84/344 (24%), Positives = 150/344 (43%), Gaps = 62/344 (18%)

Query: 58  IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 117
           +FI  L + +    L       G I   +++ D NG+ +GYAFV F  +  A  AI+++N
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS-KGYAFVHFETQEAADKAIEKMN 159

Query: 118 NYEIRNGRLLGVCASVDNCRLFVGGIPKTKKRE-EILSEMKKVT--------EGVVDVIV 168
                 G LL      ++ ++FVG     K+RE E+ ++ K+ T        E V D  +
Sbjct: 160 ------GMLL------NDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESL 207

Query: 169 YP--SAADKT-----------KNRGFAFVEYESHRAAAMARRKL----LPGRIQLWGHGI 211
               S   KT           K++GF FV YE H  A  A  ++    + G+I   G   
Sbjct: 208 KELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQ 267

Query: 212 AVDWAEPEVEVDEDTMSSVKI-------LYVRNLMLSTSEEMIEKEFNNIKPGAVERVK- 263
                + E++   + +   +I       LY++NL  +  +E + KEF+    G++   K 
Sbjct: 268 KKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPF--GSITSAKV 325

Query: 264 -----KIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDK------DSYVRY 312
                + + + FV FS+ E+A +A+  +NG+++   P+ V LA+  ++      + Y++ 
Sbjct: 326 MLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQR 385

Query: 313 TRGTGG-RGTMLQGEYTYSLGQVYDPTTTYL-GAPVFYAPQTYA 354
             G        +  ++  + G  + P      G P +Y P   A
Sbjct: 386 VAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLA 429



 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 62/271 (22%), Positives = 120/271 (44%), Gaps = 23/271 (8%)

Query: 58  IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDF-NGNNRGYAFVTFSNKVEAKNAIKQL 116
           +++G L  D+ E  L       G +  +R+  D     + GYA+V F    +A+ A+  +
Sbjct: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 117 NNYEIRNGRLLGVCASVDNCRLFVGGIPKT--KKREEILSE--MKKVTEGVVDVIVYPSA 172
            N+++  G+ + +  S  +  L   G+     K  ++ +    +        +++     
Sbjct: 73  -NFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131

Query: 173 ADKTKNRGFAFVEYESHRAAAMARRK----LLPGRIQLWGHGIAVDWAEPEVEVDEDTMS 228
            D+  ++G+AFV +E+  AA  A  K    LL  R    G   +    E E+       +
Sbjct: 132 CDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFT 191

Query: 229 SVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD-------YAFVHFSNREDAVE 281
           +V   Y++N      +E +++ F+    G    VK +RD       + FV +   EDA +
Sbjct: 192 NV---YIKNFGEEVDDESLKELFSQF--GKTLSVKVMRDPNGKSKGFGFVSYEKHEDANK 246

Query: 282 AMKALNGKVLDGSPIEVTLA-KPVDKDSYVR 311
           A++ +NGK + G  I V  A K V++ + ++
Sbjct: 247 AVEEMNGKEISGKIIFVGRAQKKVERQAELK 277


>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
           sapiens]
          Length = 644

 Score = 73.2 bits (178), Expect = 6e-13
 Identities = 84/344 (24%), Positives = 150/344 (43%), Gaps = 62/344 (18%)

Query: 58  IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 117
           +FI  L + +    L       G I   +++ D NG+ +GYAFV F  +  A  AI+++N
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS-KGYAFVHFETQEAADKAIEKMN 159

Query: 118 NYEIRNGRLLGVCASVDNCRLFVGGIPKTKKRE-EILSEMKKVT--------EGVVDVIV 168
                 G LL      ++ ++FVG     K+RE E+ ++ K+ T        E V D  +
Sbjct: 160 ------GMLL------NDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESL 207

Query: 169 YP--SAADKT-----------KNRGFAFVEYESHRAAAMARRKL----LPGRIQLWGHGI 211
               S   KT           K++GF FV YE H  A  A  ++    + G+I   G   
Sbjct: 208 KELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQ 267

Query: 212 AVDWAEPEVEVDEDTMSSVKI-------LYVRNLMLSTSEEMIEKEFNNIKPGAVERVK- 263
                + E++   + +   +I       LY++NL  +  +E + KEF+    G++   K 
Sbjct: 268 KKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPF--GSITSAKV 325

Query: 264 -----KIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDK------DSYVRY 312
                + + + FV FS+ E+A +A+  +NG+++   P+ V LA+  ++      + Y++ 
Sbjct: 326 MLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQR 385

Query: 313 TRGTGG-RGTMLQGEYTYSLGQVYDPTTTYL-GAPVFYAPQTYA 354
             G        +  ++  + G  + P      G P +Y P   A
Sbjct: 386 VAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLA 429



 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 62/271 (22%), Positives = 120/271 (44%), Gaps = 23/271 (8%)

Query: 58  IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDF-NGNNRGYAFVTFSNKVEAKNAIKQL 116
           +++G L  D+ E  L       G +  +R+  D     + GYA+V F    +A+ A+  +
Sbjct: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 117 NNYEIRNGRLLGVCASVDNCRLFVGGIPKT--KKREEILSE--MKKVTEGVVDVIVYPSA 172
            N+++  G+ + +  S  +  L   G+     K  ++ +    +        +++     
Sbjct: 73  -NFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131

Query: 173 ADKTKNRGFAFVEYESHRAAAMARRK----LLPGRIQLWGHGIAVDWAEPEVEVDEDTMS 228
            D+  ++G+AFV +E+  AA  A  K    LL  R    G   +    E E+       +
Sbjct: 132 CDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFT 191

Query: 229 SVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD-------YAFVHFSNREDAVE 281
           +V   Y++N      +E +++ F+    G    VK +RD       + FV +   EDA +
Sbjct: 192 NV---YIKNFGEEVDDESLKELFSQF--GKTLSVKVMRDPNGKSKGFGFVSYEKHEDANK 246

Query: 282 AMKALNGKVLDGSPIEVTLA-KPVDKDSYVR 311
           A++ +NGK + G  I V  A K V++ + ++
Sbjct: 247 AVEEMNGKEISGKIIFVGRAQKKVERQAELK 277


>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
           sapiens]
          Length = 660

 Score = 73.2 bits (178), Expect = 6e-13
 Identities = 84/344 (24%), Positives = 150/344 (43%), Gaps = 62/344 (18%)

Query: 58  IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 117
           +FI  L + +    L       G I   +++ D NG+ +GYAFV F  +  A  AI+++N
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS-KGYAFVHFETQEAADKAIEKMN 159

Query: 118 NYEIRNGRLLGVCASVDNCRLFVGGIPKTKKRE-EILSEMKKVT--------EGVVDVIV 168
                 G LL      ++ ++FVG     K+RE E+ ++ K+ T        E V D  +
Sbjct: 160 ------GMLL------NDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESL 207

Query: 169 YP--SAADKT-----------KNRGFAFVEYESHRAAAMARRKL----LPGRIQLWGHGI 211
               S   KT           K++GF FV YE H  A  A  ++    + G+I   G   
Sbjct: 208 KELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQ 267

Query: 212 AVDWAEPEVEVDEDTMSSVKI-------LYVRNLMLSTSEEMIEKEFNNIKPGAVERVK- 263
                + E++   + +   +I       LY++NL  +  +E + KEF+    G++   K 
Sbjct: 268 KKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPF--GSITSAKV 325

Query: 264 -----KIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDK------DSYVRY 312
                + + + FV FS+ E+A +A+  +NG+++   P+ V LA+  ++      + Y++ 
Sbjct: 326 MLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQR 385

Query: 313 TRGTGG-RGTMLQGEYTYSLGQVYDPTTTYL-GAPVFYAPQTYA 354
             G        +  ++  + G  + P      G P +Y P   A
Sbjct: 386 VAGMRALPANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLA 429



 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 62/271 (22%), Positives = 120/271 (44%), Gaps = 23/271 (8%)

Query: 58  IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDF-NGNNRGYAFVTFSNKVEAKNAIKQL 116
           +++G L  D+ E  L       G +  +R+  D     + GYA+V F    +A+ A+  +
Sbjct: 13  LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72

Query: 117 NNYEIRNGRLLGVCASVDNCRLFVGGIPKT--KKREEILSE--MKKVTEGVVDVIVYPSA 172
            N+++  G+ + +  S  +  L   G+     K  ++ +    +        +++     
Sbjct: 73  -NFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVV 131

Query: 173 ADKTKNRGFAFVEYESHRAAAMARRK----LLPGRIQLWGHGIAVDWAEPEVEVDEDTMS 228
            D+  ++G+AFV +E+  AA  A  K    LL  R    G   +    E E+       +
Sbjct: 132 CDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFT 191

Query: 229 SVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD-------YAFVHFSNREDAVE 281
           +V   Y++N      +E +++ F+    G    VK +RD       + FV +   EDA +
Sbjct: 192 NV---YIKNFGEEVDDESLKELFSQF--GKTLSVKVMRDPNGKSKGFGFVSYEKHEDANK 246

Query: 282 AMKALNGKVLDGSPIEVTLA-KPVDKDSYVR 311
           A++ +NGK + G  I V  A K V++ + ++
Sbjct: 247 AVEEMNGKEISGKIIFVGRAQKKVERQAELK 277


>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
          Length = 631

 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 75/286 (26%), Positives = 119/286 (41%), Gaps = 58/286 (20%)

Query: 58  IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 117
           IF+  L + +    L       G I    ++ D NG+ +GY FV F     A+ AIK++N
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGS-KGYGFVHFETHEAAERAIKKMN 159

Query: 118 NYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSE---------MKKVTEGVVD--- 165
              + NGR           ++FVG     K+RE  L           +K   E + D   
Sbjct: 160 GM-LLNGR-----------KVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERL 207

Query: 166 ----------VIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDW 215
                     + V     +  K++GF FV +E H  A  A  ++     +L G  I V  
Sbjct: 208 KDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEM--NGKELNGKQIYVGR 265

Query: 216 AEPEVE-------------VDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERV 262
           A+ +VE              D  T   V  LYV+NL     +E + K F+    G +   
Sbjct: 266 AQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPF--GTITSA 323

Query: 263 K------KIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAK 302
           K      + + + FV FS+ E+A +A+  +NG+++   P+ V LA+
Sbjct: 324 KVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQ 369



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 67/280 (23%), Positives = 121/280 (43%), Gaps = 19/280 (6%)

Query: 49  AAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDF-NGNNRGYAFVTFSNKV 107
           + P      +++G L  D+ E  L       G I  +R+  D     +  YA+V F +  
Sbjct: 4   STPSYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTK 63

Query: 108 EAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVV--- 164
           +A++A+  +N +++  G+ + +  S  +  L   G+     +    S   K     V   
Sbjct: 64  DAEHALDTMN-FDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAF 122

Query: 165 -DVIVYPSAADKTKNRGFAFVEYESHRAAAMARRK----LLPGRIQLWGHGIAVDWAEPE 219
            +++      D+  ++G+ FV +E+H AA  A +K    LL GR    G   +    E E
Sbjct: 123 GNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAE 182

Query: 220 VEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVK-----KIRDYAFVHFS 274
           +        +V   Y++N      +E ++  F    P    +V      K + + FV F 
Sbjct: 183 LGARAKEFPNV---YIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFE 239

Query: 275 NREDAVEAMKALNGKVLDGSPIEVTLA-KPVDKDSYVRYT 313
             EDA +A+  +NGK L+G  I V  A K V++ + ++ T
Sbjct: 240 RHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRT 279



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 38/151 (25%), Positives = 72/151 (47%), Gaps = 24/151 (15%)

Query: 17  EAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCE------IFIGKLPRDLFED 70
           EAA RA+ +  G  L   NG++ + G          E G        ++I     D+ ++
Sbjct: 149 EAAERAIKKMNGMLL---NGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDE 205

Query: 71  ELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGVC 130
            L  L  K G    +++M D +G ++G+ FV+F    +A+ A+ ++N  E+ NG+     
Sbjct: 206 RLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKEL-NGK----- 259

Query: 131 ASVDNCRLFVGGIPKTKKREEILSEMKKVTE 161
                 +++VG   + +K+ E  +E+K+  E
Sbjct: 260 ------QIYVG---RAQKKVERQTELKRTFE 281


>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
          Length = 636

 Score = 69.3 bits (168), Expect = 9e-12
 Identities = 92/362 (25%), Positives = 147/362 (40%), Gaps = 77/362 (21%)

Query: 58  IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 117
           IFI  L + +    L       G I   +++ D NG+ +GY FV F  +  A+ AI+++N
Sbjct: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGS-KGYGFVHFETQEAAERAIEKMN 159

Query: 118 NYEIRNGRLLGVCASVDNCRLFVGGIPKTKKRE-EILSEMKKVT-------------EGV 163
                 G LL      ++ ++FVG     K+RE E+ +  K+ T             E +
Sbjct: 160 ------GMLL------NDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERL 207

Query: 164 VDVI--------VYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDW 215
            D+         V     +  K++GF FV +E H  A  A  ++     +L G  I V  
Sbjct: 208 KDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEM--NGKELNGKQIYVGR 265

Query: 216 AEPEVE-------------VDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERV 262
           A+ +VE              D  T      LYV+NL     +E + KEF+    G +   
Sbjct: 266 AQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPF--GTITSA 323

Query: 263 K------KIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGT 316
           K      + + + FV FS+ E+A +A+  +NG+++   P+ V LA+  ++          
Sbjct: 324 KVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEE---------- 373

Query: 317 GGRGTMLQGEYTYSLGQVYDPTTTYLGAPVFYAPQTYAAIPSLHFPATKGHLSNRAIIRA 376
             R   L  +Y   +  V       +     Y P    A PS +F A      NRA    
Sbjct: 374 --RQAHLTNQYMQRMASVRAVPNPVINP---YQP----APPSGYFMAAIPQTQNRAAYYP 424

Query: 377 PS 378
           PS
Sbjct: 425 PS 426



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 64/278 (23%), Positives = 119/278 (42%), Gaps = 19/278 (6%)

Query: 49  AAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDF-NGNNRGYAFVTFSNKV 107
           +AP      +++G L  D+ E  L       G I  +R+  D     + GYA+V F    
Sbjct: 4   SAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPA 63

Query: 108 EAKNAIKQLNNYEIRNGRLLGVCASVDNCRLFVGGIPKT--KKREEILSE--MKKVTEGV 163
           +A+ A+  +N +++  G+ + +  S  +  L   G+     K  ++ +    +       
Sbjct: 64  DAERALDTMN-FDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAF 122

Query: 164 VDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRK----LLPGRIQLWGHGIAVDWAEPE 219
            +++      D+  ++G+ FV +E+  AA  A  K    LL  R    G   +    E E
Sbjct: 123 GNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAE 182

Query: 220 VEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVK-----KIRDYAFVHFS 274
           +       ++V   Y++N      +E ++  F    P    +V      K + + FV F 
Sbjct: 183 LGARAKEFTNV---YIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFE 239

Query: 275 NREDAVEAMKALNGKVLDGSPIEVTLA-KPVDKDSYVR 311
             EDA +A+  +NGK L+G  I V  A K V++ + ++
Sbjct: 240 RHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELK 277



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 37/152 (24%), Positives = 72/152 (47%), Gaps = 24/152 (15%)

Query: 16  KEAALRALVQRTGYSLVQENGQRKYGGPPPGWDAAPPERGCE------IFIGKLPRDLFE 69
           +EAA RA+ +  G  L   N ++ + G          E G        ++I     D+ +
Sbjct: 148 QEAAERAIEKMNGMLL---NDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDD 204

Query: 70  DELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNGRLLGV 129
           + L  L  K G    +++M D +G ++G+ FV+F    +A+ A+ ++N  E+ NG+    
Sbjct: 205 ERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKEL-NGK---- 259

Query: 130 CASVDNCRLFVGGIPKTKKREEILSEMKKVTE 161
                  +++VG   + +K+ E  +E+K+  E
Sbjct: 260 -------QIYVG---RAQKKVERQTELKRKFE 281


>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
          Length = 382

 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 74/278 (26%), Positives = 124/278 (44%), Gaps = 41/278 (14%)

Query: 58  IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAI---- 113
           IFI  L + +    L  L    G I   +++ D NG+ +GYA+V F +   A  AI    
Sbjct: 108 IFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGS-KGYAYVHFDSLAAANRAIWHMN 166

Query: 114 -KQLNNYEIRNGRLLGVCASVDNCR---------LFVGGIPKTKKREEILSEMKKVTEGV 163
             +LNN ++  GR           R         +FV  I      E+ L E+       
Sbjct: 167 GVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEK-LKELFCEYGPT 225

Query: 164 VDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVE-- 221
             V V   A+ K+K  GF FV YE+H AA  A   L    I   G  + V  A+ ++E  
Sbjct: 226 ESVKVIRDASGKSK--GFGFVRYETHEAAQKAVLDLHGKSID--GKVLYVGRAQKKIERL 281

Query: 222 -----------VDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRD--- 267
                      + E +      +Y++NL  + ++E +++EF++   G++ R K + +   
Sbjct: 282 AELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSF--GSISRAKVMMEVGQ 339

Query: 268 ---YAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAK 302
              +  V FS+ E+A +A+  +NG+++   P+ VTL +
Sbjct: 340 GKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVTLGQ 377



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 6/80 (7%)

Query: 233 LYVRNLMLSTSEEMIEKEFNNIKPGAVERV------KKIRDYAFVHFSNREDAVEAMKAL 286
           LYV +L    +E+M+ K+F    P    R+      +    Y +V+F    DA  A+  +
Sbjct: 20  LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79

Query: 287 NGKVLDGSPIEVTLAKPVDK 306
           N  +++G P  +  ++P D+
Sbjct: 80  NFDLINGKPFRLMWSQPDDR 99



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 9/78 (11%)

Query: 51  PPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAK 110
           PP  G  I+I  L   + +++L       G I   ++MM+  G  +G+  V FS+  EA 
Sbjct: 299 PP--GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEV-GQGKGFGVVCFSSFEEAT 355

Query: 111 NAIKQLNNYEIRNGRLLG 128
            A+ ++      NGR++G
Sbjct: 356 KAVDEM------NGRIVG 367


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 66/292 (22%), Positives = 128/292 (43%), Gaps = 23/292 (7%)

Query: 44  PPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTF 103
           P G D+        +    LP  + +DEL  + E   +I     ++  +G ++G A++ F
Sbjct: 381 PKGKDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEI----RLVSKDGKSKGIAYIEF 436

Query: 104 SNKVEAKNAIKQLNNYEIRNGRLLGVCASVDNCRL--FVGGIPKTKKREE---ILSEMK- 157
             + +A+   ++    EI +GR + +  + +  +   + GG   T   E    +LS +  
Sbjct: 437 KTEADAEKTFEEKQGTEI-DGRSISLYYTGEKGQNQDYRGGKNSTWSGESKTLVLSNLSY 495

Query: 158 KVTEGVVDVIVYPSAADKT------KNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGI 211
             TE  +  +   +   K       K++G+AF+E+ S   A  A        I+  G  I
Sbjct: 496 SATEETLQEVFEKATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNKREIE--GRAI 553

Query: 212 AVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKI---RDY 268
            ++   P    +  +  S K L+V+ L   T+EE +++ F+      +   ++    + +
Sbjct: 554 RLELQGPRGSPNARSQPS-KTLFVKGLSEDTTEETLKESFDGSVRARIVTDRETGSSKGF 612

Query: 269 AFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDKDSYVRYTRGTGGRG 320
            FV F++ EDA  A +A+    +DG+ + +  AKP  +  +     G GG G
Sbjct: 613 GFVDFNSEEDAKAAKEAMEDGEIDGNKVTLDWAKPKGEGGFGGRGGGRGGFG 664


>gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo
           sapiens]
          Length = 485

 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 53/175 (30%), Positives = 86/175 (49%), Gaps = 15/175 (8%)

Query: 30  SLVQENGQRKYGGPPPGWDAAPPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMM 89
           S V  +G    GG P G          ++F+G++PR L E +L PL E+ G+IYE+ ++ 
Sbjct: 22  SPVGSSGPEPPGGQPDGMKDLD---AIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLK 78

Query: 90  D-FNGNNRGYAFVTFSNKVEAKNAIKQLNNYEIRNG--RLLGVCASVDNCR------LFV 140
           D + G ++G AF+T+  +  A  A   L+  +   G  R + V  +    R      LFV
Sbjct: 79  DPYTGMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFV 138

Query: 141 GGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMA 195
           G + K +  E++L   +    GV+D        D + ++G AFV++ SH  A  A
Sbjct: 139 GMLNKQQSEEDVLRLFQPF--GVIDECTVLRGPDGS-SKGCAFVKFSSHTEAQAA 190



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 3/87 (3%)

Query: 43  PPPGWDAAPPE--RGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGN-NRGYA 99
           PPP       E   GC +FI  LP++  + EL  +    G I   ++ MD   N ++ + 
Sbjct: 385 PPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQSKCFG 444

Query: 100 FVTFSNKVEAKNAIKQLNNYEIRNGRL 126
           FV+F N   A+ AI+ +N ++I   RL
Sbjct: 445 FVSFDNPASAQAAIQAMNGFQIGMKRL 471



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 22/71 (30%), Positives = 41/71 (57%)

Query: 54  RGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAI 113
           R  ++F+G L +   E++++ L +  G I E  ++   +G+++G AFV FS+  EA+ AI
Sbjct: 132 RDRKLFVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAI 191

Query: 114 KQLNNYEIRNG 124
             L+  +   G
Sbjct: 192 HALHGSQTMPG 202



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 69/290 (23%), Positives = 119/290 (41%), Gaps = 52/290 (17%)

Query: 133 VDNCRLFVGGIPK---TKKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESH 189
           +D  +LFVG IP+    K  + +  +  ++ E  V    Y        ++G AF+ Y + 
Sbjct: 42  LDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPYTGM-----HKGCAFLTYCAR 96

Query: 190 RAA-----AMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSE 244
            +A     A+  +K LPG  +     I V  A+ E     D     + L+V  L    SE
Sbjct: 97  DSAIKAQTALHEQKTLPGMAR----PIQVKPADSESRGGRD-----RKLFVGMLNKQQSE 147

Query: 245 EMIEKEFNNIKPGAVERVKKIRD-------YAFVHFSNREDAVEAMKALNG-KVLDGSPI 296
           E + + F     G ++    +R         AFV FS+  +A  A+ AL+G + + G+  
Sbjct: 148 EDVLRLFQPF--GVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHALHGSQTMPGASS 205

Query: 297 EVTLA-KPVDKDSYVRYTRGTGGRGTMLQGEYT--------YSLGQVYDPTT------TY 341
            + +     DK+  +R  +   G+  +L    T        Y+   +   TT      +Y
Sbjct: 206 SLVVKFADTDKERTLRRMQQMVGQLGILTPSLTLPFSPYSAYAQALMQQQTTVLSTSGSY 265

Query: 342 LGAPVFYAP---QTYAAIPSLHFPATKGHLSNRAIIRAPSVRGAAGVRGL 388
           L   V ++P   Q   A+     PAT   ++  + + +P + G   V GL
Sbjct: 266 LSPGVAFSPCHIQQIGAVSLNGLPATP--IAPASGLHSPPLLGTTAVPGL 313


>gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo
           sapiens]
          Length = 448

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 46/147 (31%), Positives = 76/147 (51%), Gaps = 11/147 (7%)

Query: 57  EIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMD-FNGNNRGYAFVTFSNKVEAKNAIKQ 115
           ++FIG++PR+L E +L PL E+ GKIYE+ ++ D F G ++G AF+T+  +  A  A   
Sbjct: 55  KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114

Query: 116 LNNYEIRNG--RLLGVCASVDNCR-----LFVGGIPKTKKREEILSEMKKVTEGVVDVIV 168
           L+  +   G  R + V  +    R     LFVG + K +  +++    +    G ++   
Sbjct: 115 LHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLNKQQSEDDVRRLFEAF--GNIEECT 172

Query: 169 YPSAADKTKNRGFAFVEYESHRAAAMA 195
                D   ++G AFV+Y SH  A  A
Sbjct: 173 ILRGPD-GNSKGCAFVKYSSHAEAQAA 198



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 23/68 (33%), Positives = 39/68 (57%)

Query: 57  EIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQL 116
           ++F+G L +   ED++  L E  G I E  ++   +GN++G AFV +S+  EA+ AI  L
Sbjct: 143 KLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINAL 202

Query: 117 NNYEIRNG 124
           +  +   G
Sbjct: 203 HGSQTMPG 210



 Score = 30.4 bits (67), Expect = 4.7
 Identities = 43/168 (25%), Positives = 72/168 (42%), Gaps = 28/168 (16%)

Query: 134 DNCRLFVGGIPKT---KKREEILSEMKKVTEGVVDVIVYPSAADKTKNRGFAFVEYESHR 190
           D  +LF+G IP+    K  + +  E  K+ E  V    +        ++G AF+ Y    
Sbjct: 52  DAIKLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGM-----HKGCAFLTYCERE 106

Query: 191 AA-----AMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVRNLMLSTSEE 245
           +A     A+  +K LPG        I V  A+ E   ++      + L+V  L    SE+
Sbjct: 107 SALKAQSALHEQKTLPGM----NRPIQVKPADSESRGED------RKLFVGMLNKQQSED 156

Query: 246 MIEK---EFNNIKPGAVERVK--KIRDYAFVHFSNREDAVEAMKALNG 288
            + +    F NI+   + R      +  AFV +S+  +A  A+ AL+G
Sbjct: 157 DVRRLFEAFGNIEECTILRGPDGNSKGCAFVKYSSHAEAQAAINALHG 204


>gi|51948366 ribonucleoprotein, PTB-binding 2 [Homo sapiens]
          Length = 678

 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 66/251 (26%), Positives = 108/251 (43%), Gaps = 15/251 (5%)

Query: 57  EIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQL 116
           +I +  LP+D    E+  L     K Y+++    +   N+  AFVT  N  +A+NAI+  
Sbjct: 70  KILVKNLPQDSNCQEVHDLL----KDYDLKYC--YVDRNKRTAFVTLLNGEQAQNAIQMF 123

Query: 117 NNYEIRNGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMKKVTEGVVDVIVYPSAADKT 176
           + Y  R G+ L V     +  L +  +P +   EE    ++         +VY      +
Sbjct: 124 HQYSFR-GKDLIVQLQPTDALLCITNVPISFTSEEFEELVRAYGNIERCFLVYSEVTGHS 182

Query: 177 KNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMSSVKILYVR 236
           K  G+ FVEY     AA AR +LL GR QL    +   W +  +   E   S    +   
Sbjct: 183 K--GYGFVEYMKKDFAAKARLELL-GR-QLGASALFAQWMDVNLLASELIHSKCLCIDKL 238

Query: 237 NLMLSTSEEMIEKEFNNIKPG----AVERVKKIRDYAFVHFSNREDAVEAMKALNGKVLD 292
                 SEE+++   +  KP     A +    +  +A V +S  E A E  +A +G  + 
Sbjct: 239 PSDYRDSEELLQIFSSVHKPVFCQLAQDEGSYVGGFAVVEYSTAEQAEEVQQAADGMTIK 298

Query: 293 GSPIEVTLAKP 303
           GS ++V+   P
Sbjct: 299 GSKVQVSFCAP 309


>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
          Length = 375

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 64/296 (21%), Positives = 121/296 (40%), Gaps = 38/296 (12%)

Query: 58  IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 117
           +++G L RD+ E  ++ L  +IG     +M+MD  GN+  Y FV F     A  A+  +N
Sbjct: 9   LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67

Query: 118 NYEIRNGRLLGVCASVDNCR---------LFVGGIPKTKKREEILSEMKKVTEGVVDVIV 168
             +I    +    A+  + +         +FVG +      E+I +            +V
Sbjct: 68  GRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVV 127

Query: 169 YPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAEPEVEVDEDTMS 228
              A  K+K  G+ FV + +   A  A +++  G   L G  I  +WA  +    + T  
Sbjct: 128 KDMATGKSK--GYGFVSFFNKWDAENAIQQM--GGQWLGGRQIRTNWATRKPPAPKSTYE 183

Query: 229 SVK-----------------ILYVRNLMLSTSEEMIEKEFNNIKPGAVERVKKIRDYAFV 271
           S                    +Y   +    +E+++ + F+        RV   + Y+FV
Sbjct: 184 SNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFV 243

Query: 272 HFSNREDAVEAMKALNGKVLDGSPIE-------VTLAKPVDKDSYVRYTRGTGGRG 320
            F++ E A  A+ ++NG  ++G  ++       + +  PV + + + Y +  G  G
Sbjct: 244 RFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQIGYPQPYGQWG 299


>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
          Length = 386

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 65/307 (21%), Positives = 122/307 (39%), Gaps = 49/307 (15%)

Query: 58  IFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLN 117
           +++G L RD+ E  ++ L  +IG     +M+MD  GN+  Y FV F     A  A+  +N
Sbjct: 9   LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDP-YCFVEFHEHRHAAAALAAMN 67

Query: 118 NYEIR--------------------NGRLLGVCASVDNCRLFVGGIPKTKKREEILSEMK 157
             +I                     +  ++    S D+  +FVG +      E+I +   
Sbjct: 68  GRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFA 127

Query: 158 KVTEGVVDVIVYPSAADKTKNRGFAFVEYESHRAAAMARRKLLPGRIQLWGHGIAVDWAE 217
                    +V   A  K+K  G+ FV + +   A  A +++  G   L G  I  +WA 
Sbjct: 128 PFGRISDARVVKDMATGKSK--GYGFVSFFNKWDAENAIQQM--GGQWLGGRQIRTNWAT 183

Query: 218 PEVEVDEDTMSSVK-----------------ILYVRNLMLSTSEEMIEKEFNNIKPGAVE 260
            +    + T  S                    +Y   +    +E+++ + F+        
Sbjct: 184 RKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEI 243

Query: 261 RVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIE-------VTLAKPVDKDSYVRYT 313
           RV   + Y+FV F++ E A  A+ ++NG  ++G  ++       + +  PV + + + Y 
Sbjct: 244 RVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQIGYP 303

Query: 314 RGTGGRG 320
           +  G  G
Sbjct: 304 QPYGQWG 310


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,568,318
Number of Sequences: 37866
Number of extensions: 1156035
Number of successful extensions: 4321
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 169
Number of HSP's successfully gapped in prelim test: 99
Number of HSP's that attempted gapping in prelim test: 3453
Number of HSP's gapped (non-prelim): 672
length of query: 586
length of database: 18,247,518
effective HSP length: 108
effective length of query: 478
effective length of database: 14,157,990
effective search space: 6767519220
effective search space used: 6767519220
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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