Search of human proteins with 20127448

Search of human proteins with 20127448

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20127448 DNA-directed DNA polymerase alpha 2 [Homo sapiens]
         (598 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20127448 DNA-directed DNA polymerase alpha 2 [Homo sapiens]       1192   0.0  
gi|32189369 DNA-directed DNA polymerase epsilon 2 [Homo sapiens]       43   0.001
gi|194239640 activating transcription factor 7 isoform 1 [Homo s...    35   0.26 
gi|27436951 lamin B2 [Homo sapiens]                                    35   0.26 
gi|5802980 activating transcription factor 7 isoform 2 [Homo sap...    33   0.57 
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   32   1.3  
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   32   1.3  
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   32   1.3  
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    32   1.3  
gi|209863002 MAP-kinase activating death domain-containing prote...    32   1.7  
gi|209862998 MAP-kinase activating death domain-containing prote...    32   1.7  
gi|209862987 MAP-kinase activating death domain-containing prote...    32   1.7  
gi|209862979 MAP-kinase activating death domain-containing prote...    32   1.7  
gi|209862971 MAP-kinase activating death domain-containing prote...    32   1.7  
gi|209571517 MAP-kinase activating death domain-containing prote...    32   1.7  
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s...    32   1.7  
gi|53828926 early B-cell factor 3 [Homo sapiens]                       32   2.2  
gi|216547832 lectin, galactoside-binding, soluble, 12 isoform 5 ...    32   2.2  
gi|216547811 lectin, galactoside-binding, soluble, 12 isoform 3 ...    32   2.2  
gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]               31   2.8  
gi|7662310 FERM, RhoGEF and pleckstrin domain protein 2 [Homo sa...    31   3.7  
gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi...    30   4.8  
gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi...    30   4.8  
gi|223555921 hepatocellular carcinoma related protein 1 isoform ...    30   6.3  
gi|223555919 hepatocellular carcinoma related protein 1 isoform ...    30   6.3  
gi|194239643 activating transcription factor 7 isoform 3 [Homo s...    30   6.3  
gi|157785645 SPEG complex locus [Homo sapiens]                         30   6.3  
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]      30   8.3  
gi|169194755 PREDICTED: hypothetical protein [Homo sapiens]            30   8.3  
gi|169205589 PREDICTED: chromosome 12 open reading frame 55 [Hom...    30   8.3  

>gi|20127448 DNA-directed DNA polymerase alpha 2 [Homo sapiens]
          Length = 598

 Score = 1192 bits (3083), Expect = 0.0
 Identities = 598/598 (100%), Positives = 598/598 (100%)

Query: 1   MSASAQQLAEELQIFGLDCEEALIEKLVELCVQYGQNEEGMVGELIAFCTSTHKVGLTSE 60
           MSASAQQLAEELQIFGLDCEEALIEKLVELCVQYGQNEEGMVGELIAFCTSTHKVGLTSE
Sbjct: 1   MSASAQQLAEELQIFGLDCEEALIEKLVELCVQYGQNEEGMVGELIAFCTSTHKVGLTSE 60

Query: 61  ILNSFEHEFLSKRLSKARHSTCKDSGHAGARDIVSIQELIEVEEEEEILLNSYTTPSKGS 120
           ILNSFEHEFLSKRLSKARHSTCKDSGHAGARDIVSIQELIEVEEEEEILLNSYTTPSKGS
Sbjct: 61  ILNSFEHEFLSKRLSKARHSTCKDSGHAGARDIVSIQELIEVEEEEEILLNSYTTPSKGS 120

Query: 121 QKRAISTPETPLTKRSVSTRSPHQLLSPSSFSPSATPSQKYNSRSNRGEVVTSFGLAQGV 180
           QKRAISTPETPLTKRSVSTRSPHQLLSPSSFSPSATPSQKYNSRSNRGEVVTSFGLAQGV
Sbjct: 121 QKRAISTPETPLTKRSVSTRSPHQLLSPSSFSPSATPSQKYNSRSNRGEVVTSFGLAQGV 180

Query: 181 SWSGRGGAGNISLKVLGCPEALTGSYKSMFQKLPDIREVLTCKIEELGSELKEHYKIEAF 240
           SWSGRGGAGNISLKVLGCPEALTGSYKSMFQKLPDIREVLTCKIEELGSELKEHYKIEAF
Sbjct: 181 SWSGRGGAGNISLKVLGCPEALTGSYKSMFQKLPDIREVLTCKIEELGSELKEHYKIEAF 240

Query: 241 TPLLAPAQEPVTLLGQIGCDSNGKLNNKSVILEGDREHSSGAQIPVDLSELKEYSLFPGQ 300
           TPLLAPAQEPVTLLGQIGCDSNGKLNNKSVILEGDREHSSGAQIPVDLSELKEYSLFPGQ
Sbjct: 241 TPLLAPAQEPVTLLGQIGCDSNGKLNNKSVILEGDREHSSGAQIPVDLSELKEYSLFPGQ 300

Query: 301 VVIMEGINTTGRKLVATKLYEGVPLPFYQPTEEDADFEQSMVLVACGPYTTSDSITYDPL 360
           VVIMEGINTTGRKLVATKLYEGVPLPFYQPTEEDADFEQSMVLVACGPYTTSDSITYDPL
Sbjct: 301 VVIMEGINTTGRKLVATKLYEGVPLPFYQPTEEDADFEQSMVLVACGPYTTSDSITYDPL 360

Query: 361 LDLIAVINHDRPDVCILFGPFLDAKHEQVENCLLTSPFEDIFKQCLRTIIEGTRSSGSHL 420
           LDLIAVINHDRPDVCILFGPFLDAKHEQVENCLLTSPFEDIFKQCLRTIIEGTRSSGSHL
Sbjct: 361 LDLIAVINHDRPDVCILFGPFLDAKHEQVENCLLTSPFEDIFKQCLRTIIEGTRSSGSHL 420

Query: 421 VFVPSLRDVHHEPVYPQPPFSYSDLSREDKKQVQFVSEPCSLSINGVIFGLTSTDLLFHL 480
           VFVPSLRDVHHEPVYPQPPFSYSDLSREDKKQVQFVSEPCSLSINGVIFGLTSTDLLFHL
Sbjct: 421 VFVPSLRDVHHEPVYPQPPFSYSDLSREDKKQVQFVSEPCSLSINGVIFGLTSTDLLFHL 480

Query: 481 GAEEISSSSGTSDRFSRILKHILTQRSYYPLYPPQEDMAIDYESFYVYAQLPVTPDVLII 540
           GAEEISSSSGTSDRFSRILKHILTQRSYYPLYPPQEDMAIDYESFYVYAQLPVTPDVLII
Sbjct: 481 GAEEISSSSGTSDRFSRILKHILTQRSYYPLYPPQEDMAIDYESFYVYAQLPVTPDVLII 540

Query: 541 PSELRYFVKDVLGCVCVNPGRLTKGQVGGTFARLYLRRPAADGAERQSPCIAVQVVRI 598
           PSELRYFVKDVLGCVCVNPGRLTKGQVGGTFARLYLRRPAADGAERQSPCIAVQVVRI
Sbjct: 541 PSELRYFVKDVLGCVCVNPGRLTKGQVGGTFARLYLRRPAADGAERQSPCIAVQVVRI 598


>gi|32189369 DNA-directed DNA polymerase epsilon 2 [Homo sapiens]
          Length = 527

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 42/173 (24%), Positives = 71/173 (41%), Gaps = 9/173 (5%)

Query: 418 SHLVFVPSLRDVHHEPVYPQPPFSYSDLSREDKKQVQF---VSEPCSLSINGVIFGLTST 474
           S  VFVP   D     + P+PP + S ++ E +++V F    + PC +        +   
Sbjct: 359 SRFVFVPGPEDPGFGSILPRPPLAES-ITNEFRQRVPFSVFTTNPCRIQYCTQEITVFRE 417

Query: 475 DLLFHLGAEEISSSSGTSDRFSRILKHILTQRSYYPLYPPQEDMAIDYESFYVYAQLPVT 534
           DL+  +    +   S      +  +K IL+Q    PL  P     + +   Y     PV 
Sbjct: 418 DLVNKMCRNCVRFPSSNLAIPNHFVKTILSQGHLTPL--PLYVCPVYWAYDYALRVYPV- 474

Query: 535 PDVLIIPSELRYFVKDVLGCVCVNPGRLTKGQVGGTFARLYLRRPAADGAERQ 587
           PD+L+I  +   F      C+C+NPG   +   G +F   Y      + ++ Q
Sbjct: 475 PDLLVIADKYDPFTTTNTECLCINPGSFPRS--GFSFKVFYPSNKTVEDSKLQ 525


>gi|194239640 activating transcription factor 7 isoform 1 [Homo
           sapiens]
          Length = 494

 Score = 34.7 bits (78), Expect = 0.26
 Identities = 30/116 (25%), Positives = 55/116 (47%), Gaps = 10/116 (8%)

Query: 48  FCTSTHKVGLTSEILNSFEHEFL-----SKRLSKARHSTCKDSGHAGARDI-VSIQELIE 101
           F  +  +VGL +E+ +SFEHEF       ++ +++R    K    AG  D+ +     I+
Sbjct: 57  FLKNCEEVGLFNELASSFEHEFKKAADEDEKKARSRTVAKKLVAAAGPLDMSLPSTPDIK 116

Query: 102 VEEEEEILLNSYTTPSKGSQKRAISTPETPLTKRSVSTRSPHQLLSPSSFSPSATP 157
           ++EEE + ++S    S  S   +    E  +T + V   +P    +P+   P + P
Sbjct: 117 IKEEEPVEVDSSPPDSPASSPCSPPLKEKEVTPKPVLISTP----TPTIVRPGSLP 168


>gi|27436951 lamin B2 [Homo sapiens]
          Length = 600

 Score = 34.7 bits (78), Expect = 0.26
 Identities = 30/103 (29%), Positives = 52/103 (50%), Gaps = 7/103 (6%)

Query: 91  RDIVSIQELIEVEEEEEILLNSYTTPSKGSQKRAISTPETPLTKRSVSTRSPHQLLSPSS 150
           + +   QEL++V+   ++ +N+Y    +G ++R   +P +P ++ +VS     +  S SS
Sbjct: 349 QQLAEYQELLDVKLALDMEINAYRKLLEGEEERLKLSP-SPSSRVTVS-----RATSSSS 402

Query: 151 FSPSATPSQKYNSRSNRGEVVTSFGLAQGVSWSGRGGAGNISL 193
            S SAT  +   S+  R EV    G    V  +G GG+G   L
Sbjct: 403 GSLSAT-GRLGRSKRKRLEVEEPLGSGPSVLGTGTGGSGGFHL 444


>gi|5802980 activating transcription factor 7 isoform 2 [Homo
           sapiens]
          Length = 483

 Score = 33.5 bits (75), Expect = 0.57
 Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 11/111 (9%)

Query: 48  FCTSTHKVGLTSEILNSFEHEFLSKRLSKARHSTCKDSGHAGARDI-VSIQELIEVEEEE 106
           F  +  +VGL +E+ +SFEHEF      KA     K +  AG  D+ +     I+++EEE
Sbjct: 57  FLKNCEEVGLFNELASSFEHEF-----KKAADEDEKKAA-AGPLDMSLPSTPDIKIKEEE 110

Query: 107 EILLNSYTTPSKGSQKRAISTPETPLTKRSVSTRSPHQLLSPSSFSPSATP 157
            + ++S    S  S   +    E  +T + V   +P    +P+   P + P
Sbjct: 111 PVEVDSSPPDSPASSPCSPPLKEKEVTPKPVLISTP----TPTIVRPGSLP 157


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 32.3 bits (72), Expect = 1.3
 Identities = 19/78 (24%), Positives = 31/78 (39%), Gaps = 1/78 (1%)

Query: 95   SIQELIEVEEEEEILLNSYTTPSKGSQKRAISTPETPLTKRSVSTRSPHQLLSPSSFSPS 154
            ++ EL       E +L + T P++    + +               +PH LL P  F P 
Sbjct: 924  TMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPE 983

Query: 155  ATPSQKYNSR-SNRGEVV 171
             TP   Y  R  N+G ++
Sbjct: 984  VTPDMDYLPRVPNQGIII 1001


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 32.3 bits (72), Expect = 1.3
 Identities = 19/78 (24%), Positives = 31/78 (39%), Gaps = 1/78 (1%)

Query: 95   SIQELIEVEEEEEILLNSYTTPSKGSQKRAISTPETPLTKRSVSTRSPHQLLSPSSFSPS 154
            ++ EL       E +L + T P++    + +               +PH LL P  F P 
Sbjct: 965  TMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPE 1024

Query: 155  ATPSQKYNSR-SNRGEVV 171
             TP   Y  R  N+G ++
Sbjct: 1025 VTPDMDYLPRVPNQGIII 1042


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 32.3 bits (72), Expect = 1.3
 Identities = 19/78 (24%), Positives = 31/78 (39%), Gaps = 1/78 (1%)

Query: 95   SIQELIEVEEEEEILLNSYTTPSKGSQKRAISTPETPLTKRSVSTRSPHQLLSPSSFSPS 154
            ++ EL       E +L + T P++    + +               +PH LL P  F P 
Sbjct: 1017 TMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPE 1076

Query: 155  ATPSQKYNSR-SNRGEVV 171
             TP   Y  R  N+G ++
Sbjct: 1077 VTPDMDYLPRVPNQGIII 1094


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 32.3 bits (72), Expect = 1.3
 Identities = 19/78 (24%), Positives = 31/78 (39%), Gaps = 1/78 (1%)

Query: 95   SIQELIEVEEEEEILLNSYTTPSKGSQKRAISTPETPLTKRSVSTRSPHQLLSPSSFSPS 154
            ++ EL       E +L + T P++    + +               +PH LL P  F P 
Sbjct: 1058 TMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPE 1117

Query: 155  ATPSQKYNSR-SNRGEVV 171
             TP   Y  R  N+G ++
Sbjct: 1118 VTPDMDYLPRVPNQGIII 1135


>gi|209863002 MAP-kinase activating death domain-containing protein
           isoform j [Homo sapiens]
          Length = 1541

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 29/111 (26%), Positives = 44/111 (39%), Gaps = 9/111 (8%)

Query: 79  HSTCKDSGHAGARDIVSIQELIEVEEEEEILLNSYTTPSKGSQKRAISTPETPLTKR--- 135
           +ST  ++   G   I+S    +         L++ T P+KG++++A   P     +R   
Sbjct: 789 NSTVSNTSTEGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALV 848

Query: 136 ----SVSTRSPHQLLSPSSFSPSATPSQKYNSRSNRGEVVTSFGLAQGVSW 182
               SV   SP     P   SP    S    ++    EVV S    QGV W
Sbjct: 849 DQKSSVIKHSPTVKREPP--SPQGRSSNSSENQQFLKEVVHSVLDGQGVGW 897


>gi|209862998 MAP-kinase activating death domain-containing protein
           isoform i [Homo sapiens]
          Length = 1544

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 29/111 (26%), Positives = 44/111 (39%), Gaps = 9/111 (8%)

Query: 79  HSTCKDSGHAGARDIVSIQELIEVEEEEEILLNSYTTPSKGSQKRAISTPETPLTKR--- 135
           +ST  ++   G   I+S    +         L++ T P+KG++++A   P     +R   
Sbjct: 789 NSTVSNTSTEGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALV 848

Query: 136 ----SVSTRSPHQLLSPSSFSPSATPSQKYNSRSNRGEVVTSFGLAQGVSW 182
               SV   SP     P   SP    S    ++    EVV S    QGV W
Sbjct: 849 DQKSSVIKHSPTVKREPP--SPQGRSSNSSENQQFLKEVVHSVLDGQGVGW 897


>gi|209862987 MAP-kinase activating death domain-containing protein
           isoform f [Homo sapiens]
          Length = 1479

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 29/111 (26%), Positives = 44/111 (39%), Gaps = 9/111 (8%)

Query: 79  HSTCKDSGHAGARDIVSIQELIEVEEEEEILLNSYTTPSKGSQKRAISTPETPLTKR--- 135
           +ST  ++   G   I+S    +         L++ T P+KG++++A   P     +R   
Sbjct: 789 NSTVSNTSTEGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALV 848

Query: 136 ----SVSTRSPHQLLSPSSFSPSATPSQKYNSRSNRGEVVTSFGLAQGVSW 182
               SV   SP     P   SP    S    ++    EVV S    QGV W
Sbjct: 849 DQKSSVIKHSPTVKREPP--SPQGRSSNSSENQQFLKEVVHSVLDGQGVGW 897


>gi|209862979 MAP-kinase activating death domain-containing protein
           isoform c [Homo sapiens]
          Length = 1545

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 29/111 (26%), Positives = 44/111 (39%), Gaps = 9/111 (8%)

Query: 79  HSTCKDSGHAGARDIVSIQELIEVEEEEEILLNSYTTPSKGSQKRAISTPETPLTKR--- 135
           +ST  ++   G   I+S    +         L++ T P+KG++++A   P     +R   
Sbjct: 789 NSTVSNTSTEGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALV 848

Query: 136 ----SVSTRSPHQLLSPSSFSPSATPSQKYNSRSNRGEVVTSFGLAQGVSW 182
               SV   SP     P   SP    S    ++    EVV S    QGV W
Sbjct: 849 DQKSSVIKHSPTVKREPP--SPQGRSSNSSENQQFLKEVVHSVLDGQGVGW 897


>gi|209862971 MAP-kinase activating death domain-containing protein
           isoform a [Homo sapiens]
          Length = 1588

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 29/111 (26%), Positives = 44/111 (39%), Gaps = 9/111 (8%)

Query: 79  HSTCKDSGHAGARDIVSIQELIEVEEEEEILLNSYTTPSKGSQKRAISTPETPLTKR--- 135
           +ST  ++   G   I+S    +         L++ T P+KG++++A   P     +R   
Sbjct: 832 NSTVSNTSTEGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALV 891

Query: 136 ----SVSTRSPHQLLSPSSFSPSATPSQKYNSRSNRGEVVTSFGLAQGVSW 182
               SV   SP     P   SP    S    ++    EVV S    QGV W
Sbjct: 892 DQKSSVIKHSPTVKREPP--SPQGRSSNSSENQQFLKEVVHSVLDGQGVGW 940


>gi|209571517 MAP-kinase activating death domain-containing protein
           isoform h [Homo sapiens]
          Length = 1587

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 29/111 (26%), Positives = 44/111 (39%), Gaps = 9/111 (8%)

Query: 79  HSTCKDSGHAGARDIVSIQELIEVEEEEEILLNSYTTPSKGSQKRAISTPETPLTKR--- 135
           +ST  ++   G   I+S    +         L++ T P+KG++++A   P     +R   
Sbjct: 832 NSTVSNTSTEGFGGIMSFASSLYRNHSTSFSLSNLTLPTKGAREKATPFPSLKGNRRALV 891

Query: 136 ----SVSTRSPHQLLSPSSFSPSATPSQKYNSRSNRGEVVTSFGLAQGVSW 182
               SV   SP     P   SP    S    ++    EVV S    QGV W
Sbjct: 892 DQKSSVIKHSPTVKREPP--SPQGRSSNSSENQQFLKEVVHSVLDGQGVGW 940


>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
           sapiens]
          Length = 4911

 Score = 32.0 bits (71), Expect = 1.7
 Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 18/96 (18%)

Query: 115 TPSKGSQKRAIS----TPETPLTKRSVSTRSPHQLLSPSSFSPSATPSQK-YNSRSNRGE 169
           TP  G  K AI+    +P  P +K+     S H  +SP S+SP  +  ++ +  R   G 
Sbjct: 820 TPKIGMGKPAITKRKFSPGRPRSKQGAW--STHNTVSPPSWSPDISEGREIFKPRQLPGS 877

Query: 170 VVTSFGLAQGVSW-----------SGRGGAGNISLK 194
            + S  + +G  +           SGRGG G   LK
Sbjct: 878 AIWSIKVGRGSGFPGKRRPRGAGLSGRGGRGRSKLK 913


>gi|53828926 early B-cell factor 3 [Homo sapiens]
          Length = 551

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 27/86 (31%), Positives = 34/86 (39%), Gaps = 13/86 (15%)

Query: 120 SQKRAISTPETPLTKRSVSTRSPHQLLSPSSFSPSATPSQKYNSRSNRGEVVTSFGLAQG 179
           S + A++  ET      V        +SP  + PS+TP Q     SN   V TS      
Sbjct: 432 SSQLAVNVSETSQANDQVGYSRNTSSVSPRGYVPSSTPQQ-----SNYNTVSTSM----- 481

Query: 180 VSWSGRGGAGNISLKVLGCPEALTGS 205
              +G G     SL V G P  L GS
Sbjct: 482 ---NGYGSGAMASLGVPGSPGFLNGS 504


>gi|216547832 lectin, galactoside-binding, soluble, 12 isoform 5
           [Homo sapiens]
          Length = 266

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 19/55 (34%), Positives = 30/55 (54%), Gaps = 3/55 (5%)

Query: 253 LLGQIGCDSNGKLNNKSVILEGDREHSSGAQIPVDLSELKEYSLFPGQVVIMEGI 307
           + G I  ++ G LN    + EG RE+ +G ++P   S      L PGQV+I+ G+
Sbjct: 110 IFGDILVEAVGFLNINPFV-EGSREYPAGHEVP--CSHALPQGLSPGQVIIVRGL 161


>gi|216547811 lectin, galactoside-binding, soluble, 12 isoform 3
           [Homo sapiens]
          Length = 327

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 19/55 (34%), Positives = 30/55 (54%), Gaps = 3/55 (5%)

Query: 253 LLGQIGCDSNGKLNNKSVILEGDREHSSGAQIPVDLSELKEYSLFPGQVVIMEGI 307
           + G I  ++ G LN    + EG RE+ +G ++P   S      L PGQV+I+ G+
Sbjct: 171 IFGDILVEAVGFLNINPFV-EGSREYPAGHEVP--CSHALPQGLSPGQVIIVRGL 222


>gi|4885661 viral oncogene yes-1 homolog 1 [Homo sapiens]
          Length = 543

 Score = 31.2 bits (69), Expect = 2.8
 Identities = 36/122 (29%), Positives = 55/122 (45%), Gaps = 8/122 (6%)

Query: 117 SKGSQKRAIS-TPETPLTKRSVSTRSPHQLLSPSSFSPSATPSQKYNSRSNRGEVVTSFG 175
           SK ++  AI   PE   T   VST   H    P++ SP  + S K  + +     +T FG
Sbjct: 6   SKENKSPAIKYRPEN--TPEPVSTSVSHYGAEPTTVSPCPSSSAKGTAVNFSSLSMTPFG 63

Query: 176 LAQGVSWSGRGGAGNISLKVLGCPEALTGSYKSMFQKLPDIREVLTCKIEELGSELKEHY 235
            + GV+  G G + + S+     P  LTG   ++F  L D     T   E+L  +  E +
Sbjct: 64  GSSGVTPFG-GASSSFSVVPSSYPAGLTGGV-TIFVALYDYEARTT---EDLSFKKGERF 118

Query: 236 KI 237
           +I
Sbjct: 119 QI 120


>gi|7662310 FERM, RhoGEF and pleckstrin domain protein 2 [Homo
           sapiens]
          Length = 1054

 Score = 30.8 bits (68), Expect = 3.7
 Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 2/85 (2%)

Query: 122 KRAISTPETPLTKRSVSTRSPHQLLSPSSFSPSATPSQKYNSRSNRGEVVT--SFGLAQG 179
           K++IS PE   T  S S+ +    LSPS+  PS  P  K +S S     V+      A+ 
Sbjct: 385 KQSISFPEGLRTPASPSSANAFYSLSPSTLVPSGLPEFKDSSSSLTDPQVSYVKSPAAER 444

Query: 180 VSWSGRGGAGNISLKVLGCPEALTG 204
            S +  GG    S + LG P    G
Sbjct: 445 RSGAVAGGPDTPSAQPLGPPALQPG 469


>gi|239751395 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 30.4 bits (67), Expect = 4.8
 Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 3/53 (5%)

Query: 115 TPSKGSQKRAISTPETPLTKRSVSTRSPHQLLSPSS---FSPSATPSQKYNSR 164
           TPS        STP    + R + TRS    L+PSS    +PS+TP+   +SR
Sbjct: 185 TPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSR 237


>gi|239745904 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 30.4 bits (67), Expect = 4.8
 Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 3/53 (5%)

Query: 115 TPSKGSQKRAISTPETPLTKRSVSTRSPHQLLSPSS---FSPSATPSQKYNSR 164
           TPS        STP    + R + TRS    L+PSS    +PS+TP+   +SR
Sbjct: 185 TPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSR 237


>gi|223555921 hepatocellular carcinoma related protein 1 isoform 2
           [Homo sapiens]
          Length = 372

 Score = 30.0 bits (66), Expect = 6.3
 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 3/68 (4%)

Query: 94  VSIQELIEVEEEEEILLNSYTTPSKGSQKRAISTPETPLTKRSVSTRSPHQLLSPSSFSP 153
           +S+ +L ++ E+EE+LL  + T     Q + I T +  L K        + LL PS  + 
Sbjct: 212 LSVSQLTDMNEQEEVLLEQFLTL---PQLKQIITDKDDLVKSIEELARKNLLLEPSLEAK 268

Query: 154 SATPSQKY 161
             T   KY
Sbjct: 269 RQTVLDKY 276


>gi|223555919 hepatocellular carcinoma related protein 1 isoform 1
           [Homo sapiens]
          Length = 397

 Score = 30.0 bits (66), Expect = 6.3
 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 3/68 (4%)

Query: 94  VSIQELIEVEEEEEILLNSYTTPSKGSQKRAISTPETPLTKRSVSTRSPHQLLSPSSFSP 153
           +S+ +L ++ E+EE+LL  + T     Q + I T +  L K        + LL PS  + 
Sbjct: 237 LSVSQLTDMNEQEEVLLEQFLTL---PQLKQIITDKDDLVKSIEELARKNLLLEPSLEAK 293

Query: 154 SATPSQKY 161
             T   KY
Sbjct: 294 RQTVLDKY 301


>gi|194239643 activating transcription factor 7 isoform 3 [Homo
           sapiens]
          Length = 462

 Score = 30.0 bits (66), Expect = 6.3
 Identities = 40/132 (30%), Positives = 59/132 (44%), Gaps = 17/132 (12%)

Query: 48  FCTSTHKVGLTSEILNSFEHEFLSKRLSKARHSTCKDSGHAGARDI-VSIQELIEVEEEE 106
           F  +  +VGL +E+ +SFEHEF      KA     K +  AG  D+ +     I+++EEE
Sbjct: 57  FLKNCEEVGLFNELASSFEHEF-----KKAADEDEKKAA-AGPLDMSLPSTPDIKIKEEE 110

Query: 107 EILLNSYTTPSKGSQKRAISTPETPLTKR--SVSTRSPHQLLSPSSFSPSATPSQKYNSR 164
            +      TP    +   ISTP TP   R  S+     +  L P+  SP++  +Q   S 
Sbjct: 111 PV---EEVTP----KPVLISTP-TPTIVRPGSLPLHLGYDPLHPTLPSPTSVITQAPPSN 162

Query: 165 SNRGEVVTSFGL 176
              G    S  L
Sbjct: 163 RQMGSPTGSLPL 174


>gi|157785645 SPEG complex locus [Homo sapiens]
          Length = 3267

 Score = 30.0 bits (66), Expect = 6.3
 Identities = 26/90 (28%), Positives = 34/90 (37%), Gaps = 1/90 (1%)

Query: 91  RDIVSIQELIEVEEEEEILLNSYTTPSKGSQKRAISTPETPLTKRSVSTRSPHQLLSPSS 150
           R   S +EL+   E     L    +P +  +    S P TP T R+VS  +  Q  SPSS
Sbjct: 502 RRSTSREELVRSHESLRATLQRAPSPREPGEPPLFSRPSTPKTSRAVSPAAA-QPPSPSS 560

Query: 151 FSPSATPSQKYNSRSNRGEVVTSFGLAQGV 180
                    +  SR   G      G  Q V
Sbjct: 561 AEKPGDEPGRPRSRGPAGRTEPGEGPQQEV 590


>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
          Length = 4753

 Score = 29.6 bits (65), Expect = 8.3
 Identities = 14/37 (37%), Positives = 18/37 (48%)

Query: 416 SGSHLVFVPSLRDVHHEPVYPQPPFSYSDLSREDKKQ 452
           S SH    P  R +HH P  P  PF  +  SR+  K+
Sbjct: 143 SASHADCCPQKRRLHHRPPCPACPFVQAQWSRQQVKE 179


>gi|169194755 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 243

 Score = 29.6 bits (65), Expect = 8.3
 Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 4/72 (5%)

Query: 103 EEEEEILLNSYTTPSKGSQKRAISTPETPLTKRSVSTRSPHQLLSPS--SFSPSATPSQK 160
           EE +E +      P++G+Q  A+ TP   L ++S     P   LSPS  SF+   T + +
Sbjct: 119 EERKEEIQACDPDPTRGAQTPALGTPGERLLRQSSVQHQP--ALSPSFCSFAAVLTETLR 176

Query: 161 YNSRSNRGEVVT 172
           Y+ + +  E  T
Sbjct: 177 YHCQGSFAESST 188


>gi|169205589 PREDICTED: chromosome 12 open reading frame 55 [Homo
            sapiens]
          Length = 1241

 Score = 29.6 bits (65), Expect = 8.3
 Identities = 26/118 (22%), Positives = 49/118 (41%), Gaps = 12/118 (10%)

Query: 128  PETPLTKRSVSTRSPHQLLSPSSFSPSATPSQKYNSRSNRGEVVTSFGLAQGVSWSGRGG 187
            PE   +K+S+ T+ P Q+L P   +      + +  +  +  V +             GG
Sbjct: 1091 PEEDSSKKSLKTKKPQQILLPEKINEQLALLETHLLKLTKQYVTSELS----------GG 1140

Query: 188  AGNISLKVLGCPEALTGSYKSM--FQKLPDIREVLTCKIEELGSELKEHYKIEAFTPL 243
               I L  +    ++ G+ K +  F++ P   E  T  + +  +E K H  +E  TP+
Sbjct: 1141 EDPIFLYPVVLNWSVKGAVKEVMKFKQKPRFLEFFTQVMLKCMNEEKFHLMVEVTTPV 1198


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,002,387
Number of Sequences: 37866
Number of extensions: 1146888
Number of successful extensions: 3414
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 3352
Number of HSP's gapped (non-prelim): 85
length of query: 598
length of database: 18,247,518
effective HSP length: 108
effective length of query: 490
effective length of database: 14,157,990
effective search space: 6937415100
effective search space used: 6937415100
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.